Browse entries in the PDBbind-CN Database
HEADER IMMUNE SYSTEM/DNA 15-MAY-01 1J75 TITLE CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN ZALPHA OF DLM-1 BOUND TO TITLE 2 Z-DNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: 5'-D(*TP*CP*GP*CP*GP*CP*G)-3'; COMPND 3 CHAIN: B; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: TUMOR STROMA AND ACTIVATED MACROPHAGE PROTEIN DLM-1; COMPND 7 CHAIN: A; COMPND 8 FRAGMENT: N-TERMINAL WINGED-HELIX DOMAIN ZALPHA; COMPND 9 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 MOL_ID: 2; SOURCE 4 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 5 ORGANISM_COMMON: HOUSE MOUSE; SOURCE 6 ORGANISM_TAXID: 10090; SOURCE 7 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 8 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 9 EXPRESSION_SYSTEM_STRAIN: NOVABLUE (DE3); SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PET28A KEYWDS PROTEIN-Z-DNA COMPLEX, IMMUNE SYSTEM-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR T.SCHWARTZ,J.BEHLKE,K.LOWENHAUPT,U.HEINEMANN,A.RICH REVDAT 3 16-NOV-11 1J75 1 VERSN HETATM REVDAT 2 24-FEB-09 1J75 1 VERSN REVDAT 1 01-SEP-01 1J75 0 JRNL AUTH T.SCHWARTZ,J.BEHLKE,K.LOWENHAUPT,U.HEINEMANN,A.RICH JRNL TITL STRUCTURE OF THE DLM-1-Z-DNA COMPLEX REVEALS A CONSERVED JRNL TITL 2 FAMILY OF Z-DNA-BINDING PROTEINS. JRNL REF NAT.STRUCT.BIOL. V. 8 761 2001 JRNL REFN ISSN 1072-8368 JRNL PMID 11524677 JRNL DOI 10.1038/NSB0901-761 REMARK 2 REMARK 2 RESOLUTION. 1.85 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : CNS 1.0 REMARK 3 AUTHORS : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- REMARK 3 : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES,PANNU, REMARK 3 : READ,RICE,SIMONSON,WARREN REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.85 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 32.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 DATA CUTOFF HIGH (ABS(F)) : NULL REMARK 3 DATA CUTOFF LOW (ABS(F)) : NULL REMARK 3 COMPLETENESS (WORKING+TEST) (%) : 99.5 REMARK 3 NUMBER OF REFLECTIONS : 7778 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM R VALUE (WORKING + REMARK 3 TEST SET) : 0.22152 REMARK 3 R VALUE (WORKING SET) : 0.218 REMARK 3 FREE R VALUE : 0.240 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 10.600 REMARK 3 FREE R VALUE TEST SET COUNT : 826 REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : NULL REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 1.85 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 1.88 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 99.50 REMARK 3 REFLECTIONS IN BIN (WORKING SET) : NULL REMARK 3 BIN R VALUE (WORKING SET) : 0.2790 REMARK 3 BIN FREE R VALUE : 0.3130 REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : NULL REMARK 3 BIN FREE R VALUE TEST SET COUNT : 53 REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 444 REMARK 3 NUCLEIC ACID ATOMS : 140 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 102 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 37.60 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 21.30 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 0.08000 REMARK 3 B22 (A**2) : 0.08000 REMARK 3 B33 (A**2) : -0.12000 REMARK 3 B12 (A**2) : 0.04000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM LUZZATI PLOT (A) : NULL REMARK 3 ESD FROM SIGMAA (A) : NULL REMARK 3 LOW RESOLUTION CUTOFF (A) : NULL REMARK 3 REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : NULL REMARK 3 ESD FROM C-V SIGMAA (A) : NULL REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES. REMARK 3 BOND LENGTHS (A) : 0.019 REMARK 3 BOND ANGLES (DEGREES) : 1.59 REMARK 3 DIHEDRAL ANGLES (DEGREES) : NULL REMARK 3 IMPROPER ANGLES (DEGREES) : NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL MODEL : NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA REMARK 3 MAIN-CHAIN BOND (A**2) : 1.610 ; NULL REMARK 3 MAIN-CHAIN ANGLE (A**2) : 2.600 ; 5.549 REMARK 3 SIDE-CHAIN BOND (A**2) : NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE (A**2) : NULL ; NULL REMARK 3 REMARK 3 BULK SOLVENT MODELING. REMARK 3 METHOD USED : BABINET MODEL WITH MASK PARAMETERS FOR MASK REMARK 3 CALCULATION VDW PROBE RADIUS : 1.40 ION PROBE REMARK 3 RADIUS : 0.80 SHRINKAGE RADIUS : 0.80 REMARK 3 KSOL : NULL REMARK 3 BSOL : NULL REMARK 3 REMARK 3 NCS MODEL : NULL REMARK 3 REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL REMARK 3 REMARK 3 PARAMETER FILE 1 : NULL REMARK 3 TOPOLOGY FILE 1 : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: CNS 1.0 AND REFMAC5 USED IN REFINEMENT REMARK 4 REMARK 4 1J75 COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 17-MAY-01. REMARK 100 THE RCSB ID CODE IS RCSB013443. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 16-AUG-00 REMARK 200 TEMPERATURE (KELVIN) : 100.0 REMARK 200 PH : 6.00 REMARK 200 NUMBER OF CRYSTALS USED : 2 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : EMBL/DESY, HAMBURG REMARK 200 BEAMLINE : X11 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9102 REMARK 200 MONOCHROMATOR : MIRRORS REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : MARRESEARCH REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO REMARK 200 DATA SCALING SOFTWARE : SCALEPACK REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 7802 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.850 REMARK 200 RESOLUTION RANGE LOW (A) : 32.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 0.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.8 REMARK 200 DATA REDUNDANCY : 23.400 REMARK 200 R MERGE (I) : 0.06600 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 6.7000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.85 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.88 REMARK 200 COMPLETENESS FOR SHELL (%) : 99.5 REMARK 200 DATA REDUNDANCY IN SHELL : 7.90 REMARK 200 R MERGE FOR SHELL (I) : 0.61300 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.900 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: EPMR REMARK 200 STARTING MODEL: PDB ENTRY 1QBJ REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 52.20 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.59 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 15% PEG 4000, 0.1M AMMONIUM HYDROGEN REMARK 280 PHOSPHATE, 15% ETHYLENE GLYCOL, 0.1M MES PH 6.0, PH 6.00, VAPOR REMARK 280 DIFFUSION, HANGING DROP, TEMPERATURE 297K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 65 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+2/3 REMARK 290 3555 -X+Y,-X,Z+1/3 REMARK 290 4555 -X,-Y,Z+1/2 REMARK 290 5555 Y,-X+Y,Z+1/6 REMARK 290 6555 X-Y,X,Z+5/6 REMARK 290 7555 Y,X,-Z+2/3 REMARK 290 8555 X-Y,-Y,-Z REMARK 290 9555 -X,-X+Y,-Z+1/3 REMARK 290 10555 -Y,-X,-Z+1/6 REMARK 290 11555 -X+Y,Y,-Z+1/2 REMARK 290 12555 X,X-Y,-Z+5/6 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 48.15867 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 24.07933 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 36.11900 REMARK 290 SMTRY1 5 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 12.03967 REMARK 290 SMTRY1 6 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 60.19833 REMARK 290 SMTRY1 7 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 7 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 48.15867 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 9 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 9 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 9 0.000000 0.000000 -1.000000 24.07933 REMARK 290 SMTRY1 10 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 10 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 10 0.000000 0.000000 -1.000000 12.03967 REMARK 290 SMTRY1 11 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 11 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 11 0.000000 0.000000 -1.000000 36.11900 REMARK 290 SMTRY1 12 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 12 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 12 0.000000 0.000000 -1.000000 60.19833 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: B, A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 BIOMT1 2 -1.000000 0.000000 0.000000 -63.61100 REMARK 350 BIOMT2 2 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 2 0.000000 0.000000 -1.000000 36.11900 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 HOH B 391 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 335 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 338 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 399 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 339 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 104 REMARK 465 SER A 105 REMARK 465 HIS A 106 REMARK 465 MET A 107 REMARK 465 LEU A 108 REMARK 465 SER A 109 REMARK 465 THR A 110 REMARK 465 GLY A 111 REMARK 465 ASP A 112 REMARK 465 GLY A 170 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 LYS A 142 CD CE NZ REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O HOH A 350 O HOH B 333 2.14 REMARK 500 OD1 ASN A 113 O HOH A 378 2.15 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DT B 200 O4' - C1' - N1 ANGL. DEV. = 2.4 DEGREES REMARK 500 DC B 203 O4' - C1' - N1 ANGL. DEV. = 2.3 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 HOH A 358 DISTANCE = 5.54 ANGSTROMS REMARK 525 HOH A 359 DISTANCE = 6.53 ANGSTROMS REMARK 525 HOH A 360 DISTANCE = 6.92 ANGSTROMS REMARK 525 HOH A 363 DISTANCE = 5.38 ANGSTROMS REMARK 525 HOH A 366 DISTANCE = 6.08 ANGSTROMS REMARK 525 HOH A 379 DISTANCE = 6.24 ANGSTROMS REMARK 525 HOH B 362 DISTANCE = 9.09 ANGSTROMS REMARK 525 HOH B 391 DISTANCE = 6.84 ANGSTROMS DBREF 1J75 A 108 170 UNP Q9QY24 ZBP1_MOUSE 8 70 DBREF 1J75 B 200 206 PDB 1J75 1J75 200 206 SEQADV 1J75 GLY A 104 UNP Q9QY24 CLONING ARTIFACT SEQADV 1J75 SER A 105 UNP Q9QY24 CLONING ARTIFACT SEQADV 1J75 HIS A 106 UNP Q9QY24 CLONING ARTIFACT SEQADV 1J75 MET A 107 UNP Q9QY24 CLONING ARTIFACT SEQRES 1 B 7 DT DC DG DC DG DC DG SEQRES 1 A 67 GLY SER HIS MET LEU SER THR GLY ASP ASN LEU GLU GLN SEQRES 2 A 67 LYS ILE LEU GLN VAL LEU SER ASP ASP GLY GLY PRO VAL SEQRES 3 A 67 LYS ILE GLY GLN LEU VAL LYS LYS CYS GLN VAL PRO LYS SEQRES 4 A 67 LYS THR LEU ASN GLN VAL LEU TYR ARG LEU LYS LYS GLU SEQRES 5 A 67 ASP ARG VAL SER SER PRO GLU PRO ALA THR TRP SER ILE SEQRES 6 A 67 GLY GLY FORMUL 3 HOH *102(H2 O) HELIX 1 1 ASN A 113 GLY A 126 1 14 HELIX 2 2 ILE A 131 GLN A 139 1 9 HELIX 3 3 PRO A 141 GLU A 155 1 15 SHEET 1 A 3 VAL A 129 LYS A 130 0 SHEET 2 A 3 THR A 165 ILE A 168 -1 N TRP A 166 O VAL A 129 SHEET 3 A 3 VAL A 158 GLU A 162 -1 O SER A 159 N SER A 167 CRYST1 63.611 63.611 72.238 90.00 90.00 120.00 P 65 2 2 12 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.015721 0.009076 0.000000 0.00000 SCALE2 0.000000 0.018153 0.000000 0.00000 SCALE3 0.000000 0.000000 0.013843 0.00000 ATOM 1 O5' DT B 200 -21.640 -23.611 27.469 1.00 85.12 O ATOM 2 C5' DT B 200 -22.733 -24.372 28.004 1.00 86.21 C ATOM 3 C4' DT B 200 -23.353 -25.324 26.988 1.00 85.74 C ATOM 4 O4' DT B 200 -22.613 -26.573 26.929 1.00 89.02 O ATOM 5 C3' DT B 200 -24.779 -25.732 27.330 1.00 82.47 C ATOM 6 O3' DT B 200 -25.554 -26.092 26.187 1.00 69.70 O ATOM 7 C2' DT B 200 -24.607 -26.982 28.168 1.00 86.89 C ATOM 8 C1' DT B 200 -23.289 -27.566 27.683 1.00 89.87 C ATOM 9 N1 DT B 200 -22.479 -27.970 28.865 1.00 94.52 N ATOM 10 C2 DT B 200 -22.284 -29.307 29.146 1.00 96.61 C ATOM 11 O2 DT B 200 -22.720 -30.221 28.464 1.00 99.33 O ATOM 12 N3 DT B 200 -21.536 -29.526 30.273 1.00 97.08 N ATOM 13 C4 DT B 200 -20.995 -28.579 31.138 1.00 97.83 C ATOM 14 O4 DT B 200 -20.337 -28.888 32.137 1.00 97.90 O ATOM 15 C5 DT B 200 -21.242 -27.202 30.785 1.00 97.92 C ATOM 16 C7 DT B 200 -20.636 -26.086 31.597 1.00 98.00 C ATOM 17 C6 DT B 200 -21.967 -26.968 29.682 1.00 96.36 C ATOM 18 P DC B 201 -27.091 -25.697 26.178 1.00 49.15 P ATOM 19 OP1 DC B 201 -27.538 -25.565 27.564 1.00 82.38 O ATOM 20 OP2 DC B 201 -27.784 -26.633 25.259 1.00 82.94 O ATOM 21 O5' DC B 201 -27.065 -24.214 25.579 1.00 42.48 O ATOM 22 C5' DC B 201 -26.567 -23.994 24.266 1.00 65.22 C ATOM 23 C4' DC B 201 -26.174 -22.542 24.118 1.00 53.54 C ATOM 24 O4' DC B 201 -27.366 -21.744 24.368 1.00 45.33 O ATOM 25 C3' DC B 201 -25.144 -22.086 25.138 1.00 48.05 C ATOM 26 O3' DC B 201 -24.362 -21.019 24.714 1.00 53.26 O ATOM 27 C2' DC B 201 -26.040 -21.620 26.266 1.00 44.72 C ATOM 28 C1' DC B 201 -27.127 -20.909 25.456 1.00 43.42 C ATOM 29 N1 DC B 201 -28.441 -20.745 26.134 1.00 16.50 N ATOM 30 C2 DC B 201 -28.768 -19.535 26.729 1.00 35.69 C ATOM 31 O2 DC B 201 -27.935 -18.613 26.730 1.00 40.87 O ATOM 32 N3 DC B 201 -29.984 -19.398 27.321 1.00 39.55 N ATOM 33 C4 DC B 201 -30.822 -20.412 27.314 1.00 38.37 C ATOM 34 N4 DC B 201 -32.029 -20.272 27.908 1.00 46.27 N ATOM 35 C5 DC B 201 -30.491 -21.678 26.680 1.00 40.81 C ATOM 36 C6 DC B 201 -29.301 -21.791 26.126 1.00 44.42 C ATOM 37 P DG B 202 -22.902 -21.214 24.096 1.00 22.72 P ATOM 38 OP1 DG B 202 -22.168 -22.287 24.783 1.00 48.56 O ATOM 39 OP2 DG B 202 -22.357 -19.835 24.039 1.00 46.57 O ATOM 40 O5' DG B 202 -23.240 -21.770 22.683 1.00 26.47 O ATOM 41 C5' DG B 202 -23.954 -20.910 21.803 1.00 46.75 C ATOM 42 C4' DG B 202 -24.152 -21.658 20.525 1.00 53.99 C ATOM 43 O4' DG B 202 -24.919 -22.877 20.761 1.00 49.66 O ATOM 44 C3' DG B 202 -24.890 -20.835 19.501 1.00 53.40 C ATOM 45 O3' DG B 202 -24.041 -20.343 18.507 1.00 48.80 O ATOM 46 C2' DG B 202 -25.934 -21.786 18.929 1.00 55.05 C ATOM 47 C1' DG B 202 -25.990 -22.991 19.839 1.00 46.69 C ATOM 48 N9 DG B 202 -27.238 -23.070 20.582 1.00 23.42 N ATOM 49 C8 DG B 202 -28.001 -24.189 20.819 1.00 54.30 C ATOM 50 N7 DG B 202 -29.048 -23.955 21.553 1.00 46.13 N ATOM 51 C5 DG B 202 -28.988 -22.617 21.810 1.00 43.85 C ATOM 52 C6 DG B 202 -29.868 -21.813 22.561 1.00 43.33 C ATOM 53 O6 DG B 202 -30.920 -22.140 23.154 1.00 43.41 O ATOM 54 N1 DG B 202 -29.434 -20.503 22.596 1.00 37.56 N ATOM 55 C2 DG B 202 -28.303 -20.017 21.998 1.00 40.80 C ATOM 56 N2 DG B 202 -28.058 -18.736 22.164 1.00 36.74 N ATOM 57 N3 DG B 202 -27.465 -20.768 21.304 1.00 41.01 N ATOM 58 C4 DG B 202 -27.884 -22.050 21.250 1.00 42.50 C ATOM 59 P DC B 203 -24.046 -18.832 18.073 1.00 16.97 P ATOM 60 OP1 DC B 203 -22.982 -18.724 17.010 1.00 43.14 O ATOM 61 OP2 DC B 203 -23.973 -18.032 19.274 1.00 41.21 O ATOM 62 O5' DC B 203 -25.459 -18.627 17.377 1.00 17.55 O ATOM 63 C5' DC B 203 -25.634 -17.715 16.281 1.00 46.36 C ATOM 64 C4' DC B 203 -26.890 -16.877 16.483 1.00 42.77 C ATOM 65 O4' DC B 203 -28.014 -17.763 16.637 1.00 43.17 O ATOM 66 C3' DC B 203 -26.827 -15.988 17.703 1.00 42.82 C ATOM 67 O3' DC B 203 -27.408 -14.698 17.442 1.00 40.33 O ATOM 68 C2' DC B 203 -27.690 -16.735 18.730 1.00 46.41 C ATOM 69 C1' DC B 203 -28.741 -17.341 17.784 1.00 47.27 C ATOM 70 N1 DC B 203 -29.494 -18.465 18.363 1.00 16.82 N ATOM 71 C2 DC B 203 -30.520 -18.164 19.251 1.00 42.45 C ATOM 72 O2 DC B 203 -30.762 -16.961 19.525 1.00 38.67 O ATOM 73 N3 DC B 203 -31.206 -19.186 19.785 1.00 41.80 N ATOM 74 C4 DC B 203 -30.906 -20.442 19.460 1.00 44.03 C ATOM 75 N4 DC B 203 -31.640 -21.433 20.010 1.00 46.28 N ATOM 76 C5 DC B 203 -29.856 -20.744 18.558 1.00 45.34 C ATOM 77 C6 DC B 203 -29.167 -19.739 18.049 1.00 36.59 C ATOM 78 P DG B 204 -26.584 -13.387 17.176 1.00 20.65 P ATOM 79 OP1 DG B 204 -25.309 -13.396 17.952 1.00 52.85 O ATOM 80 OP2 DG B 204 -27.451 -12.213 17.271 1.00 40.79 O ATOM 81 O5' DG B 204 -26.183 -13.603 15.655 1.00 17.41 O ATOM 82 C5' DG B 204 -27.182 -13.711 14.699 1.00 51.66 C ATOM 83 C4' DG B 204 -26.603 -13.939 13.343 1.00 43.63 C ATOM 84 O4' DG B 204 -25.971 -15.213 13.374 1.00 39.99 O ATOM 85 C3' DG B 204 -27.666 -13.977 12.253 1.00 40.21 C ATOM 86 O3' DG B 204 -27.599 -12.785 11.545 1.00 43.84 O ATOM 87 C2' DG B 204 -27.289 -15.181 11.388 1.00 38.05 C ATOM 88 C1' DG B 204 -26.307 -15.978 12.241 1.00 38.28 C ATOM 89 N9 DG B 204 -26.819 -17.238 12.702 1.00 13.28 N ATOM 90 C8 DG B 204 -26.257 -18.463 12.573 1.00 37.31 C ATOM 91 N7 DG B 204 -27.004 -19.443 13.089 1.00 41.86 N ATOM 92 C5 DG B 204 -28.115 -18.806 13.603 1.00 41.47 C ATOM 93 C6 DG B 204 -29.248 -19.321 14.277 1.00 45.57 C ATOM 94 O6 DG B 204 -29.511 -20.486 14.572 1.00 46.88 O ATOM 95 N1 DG B 204 -30.172 -18.319 14.609 1.00 43.78 N ATOM 96 C2 DG B 204 -29.997 -17.007 14.320 1.00 42.96 C ATOM 97 N2 DG B 204 -30.966 -16.185 14.721 1.00 41.02 N ATOM 98 N3 DG B 204 -28.911 -16.511 13.698 1.00 42.57 N ATOM 99 C4 DG B 204 -28.052 -17.461 13.363 1.00 41.37 C ATOM 100 P DC B 205 -28.954 -12.009 11.168 1.00 20.05 P ATOM 101 OP1 DC B 205 -28.562 -10.902 10.311 1.00 49.84 O ATOM 102 OP2 DC B 205 -29.673 -11.755 12.418 1.00 47.23 O ATOM 103 O5' DC B 205 -29.732 -13.188 10.392 1.00 19.50 O ATOM 104 C5' DC B 205 -30.679 -12.903 9.382 1.00 48.97 C ATOM 105 C4' DC B 205 -32.083 -13.352 9.765 1.00 44.47 C ATOM 106 O4' DC B 205 -32.150 -14.790 9.687 1.00 40.59 O ATOM 107 C3' DC B 205 -32.528 -12.984 11.205 1.00 45.58 C ATOM 108 O3' DC B 205 -33.893 -12.732 11.310 1.00 50.50 O ATOM 109 C2' DC B 205 -32.203 -14.245 11.958 1.00 49.68 C ATOM 110 C1' DC B 205 -32.598 -15.281 10.925 1.00 46.38 C ATOM 111 N1 DC B 205 -32.045 -16.642 11.092 1.00 16.01 N ATOM 112 C2 DC B 205 -32.876 -17.569 11.727 1.00 38.11 C ATOM 113 O2 DC B 205 -33.990 -17.179 12.056 1.00 39.83 O ATOM 114 N3 DC B 205 -32.438 -18.856 11.887 1.00 38.45 N ATOM 115 C4 DC B 205 -31.205 -19.162 11.442 1.00 40.09 C ATOM 116 N4 DC B 205 -30.747 -20.395 11.612 1.00 42.08 N ATOM 117 C5 DC B 205 -30.338 -18.203 10.839 1.00 38.34 C ATOM 118 C6 DC B 205 -30.782 -16.960 10.675 1.00 41.05 C ATOM 119 P DG B 206 -34.525 -11.287 11.113 1.00 28.71 P ATOM 120 OP1 DG B 206 -33.708 -10.247 11.755 1.00 51.45 O ATOM 121 OP2 DG B 206 -35.987 -11.415 11.394 1.00 50.20 O ATOM 122 O5' DG B 206 -34.343 -11.030 9.563 1.00 29.27 O ATOM 123 C5' DG B 206 -35.284 -11.593 8.643 1.00 51.24 C ATOM 124 C4' DG B 206 -34.856 -11.184 7.271 1.00 63.18 C ATOM 125 O4' DG B 206 -33.513 -11.673 7.042 1.00 62.32 O ATOM 126 C3' DG B 206 -35.738 -11.683 6.160 1.00 72.87 C ATOM 127 O3' DG B 206 -36.086 -10.652 5.248 1.00 71.58 O ATOM 128 C2' DG B 206 -34.884 -12.751 5.506 1.00 76.73 C ATOM 129 C1' DG B 206 -33.453 -12.320 5.814 1.00 63.26 C ATOM 130 N9 DG B 206 -32.536 -13.414 5.982 1.00 23.68 N ATOM 131 C8 DG B 206 -31.207 -13.522 5.632 1.00 54.91 C ATOM 132 N7 DG B 206 -30.685 -14.678 5.947 1.00 46.06 N ATOM 133 C5 DG B 206 -31.741 -15.346 6.554 1.00 45.22 C ATOM 134 C6 DG B 206 -31.813 -16.640 7.103 1.00 46.86 C ATOM 135 O6 DG B 206 -30.920 -17.494 7.196 1.00 40.50 O ATOM 136 N1 DG B 206 -33.100 -16.903 7.594 1.00 48.04 N ATOM 137 C2 DG B 206 -34.154 -16.032 7.549 1.00 49.10 C ATOM 138 N2 DG B 206 -35.358 -16.413 8.094 1.00 46.80 N ATOM 139 N3 DG B 206 -34.082 -14.837 7.035 1.00 44.53 N ATOM 140 C4 DG B 206 -32.869 -14.583 6.571 1.00 48.18 C TER 141 DG B 206 ATOM 142 N ASN A 113 -13.113 -2.335 7.485 1.00 65.31 N ATOM 143 CA ASN A 113 -13.618 -3.698 7.174 1.00 62.38 C ATOM 144 C ASN A 113 -13.524 -4.624 8.391 1.00 58.62 C ATOM 145 O ASN A 113 -12.438 -4.906 8.936 1.00 57.60 O ATOM 146 CB ASN A 113 -12.897 -4.316 6.000 1.00 63.50 C ATOM 147 CG ASN A 113 -13.641 -5.491 5.438 1.00 64.94 C ATOM 148 OD1 ASN A 113 -14.700 -5.331 4.800 1.00 70.17 O ATOM 149 ND2 ASN A 113 -13.130 -6.685 5.689 1.00 61.06 N ATOM 150 N LEU A 114 -14.686 -4.966 8.892 1.00 54.76 N ATOM 151 CA LEU A 114 -14.838 -5.912 9.950 1.00 51.62 C ATOM 152 C LEU A 114 -14.275 -7.288 9.581 1.00 48.39 C ATOM 153 O LEU A 114 -13.629 -7.951 10.395 1.00 43.32 O ATOM 154 CB LEU A 114 -16.317 -6.017 10.279 1.00 51.08 C ATOM 155 CG LEU A 114 -16.662 -6.895 11.477 1.00 47.55 C ATOM 156 CD1 LEU A 114 -15.868 -6.496 12.698 1.00 47.13 C ATOM 157 CD2 LEU A 114 -18.177 -6.755 11.725 1.00 47.25 C ATOM 158 N GLU A 115 -14.534 -7.696 8.352 1.00 45.93 N ATOM 159 CA GLU A 115 -14.060 -8.981 7.865 1.00 45.80 C ATOM 160 C GLU A 115 -12.526 -9.142 8.038 1.00 44.79 C ATOM 161 O GLU A 115 -12.054 -10.174 8.550 1.00 39.90 O ATOM 162 CB GLU A 115 -14.539 -9.177 6.437 1.00 47.28 C ATOM 163 CG GLU A 115 -14.370 -10.568 5.858 1.00 51.77 C ATOM 164 CD GLU A 115 -14.569 -10.598 4.355 1.00 56.52 C ATOM 165 OE1 GLU A 115 -15.669 -10.265 3.913 1.00 58.13 O ATOM 166 OE2 GLU A 115 -13.598 -10.945 3.630 1.00 65.85 O ATOM 167 N GLN A 116 -11.753 -8.136 7.644 1.00 46.49 N ATOM 168 CA GLN A 116 -10.298 -8.217 7.763 1.00 49.25 C ATOM 169 C GLN A 116 -9.882 -8.224 9.210 1.00 46.47 C ATOM 170 O GLN A 116 -8.961 -8.928 9.578 1.00 45.96 O ATOM 171 CB GLN A 116 -9.574 -7.118 6.990 1.00 52.88 C ATOM 172 CG GLN A 116 -9.577 -7.341 5.470 1.00 56.82 C ATOM 173 CD GLN A 116 -8.958 -8.691 5.067 1.00 65.28 C ATOM 174 OE1 GLN A 116 -7.907 -9.098 5.601 1.00 65.72 O ATOM 175 NE2 GLN A 116 -9.622 -9.393 4.133 1.00 67.07 N ATOM 176 N LYS A 117 -10.576 -7.436 10.034 1.00 44.36 N ATOM 177 CA LYS A 117 -10.240 -7.371 11.447 1.00 44.08 C ATOM 178 C LYS A 117 -10.483 -8.725 12.136 1.00 40.42 C ATOM 179 O LYS A 117 -9.736 -9.151 12.980 1.00 37.92 O ATOM 180 CB LYS A 117 -11.051 -6.282 12.123 1.00 45.72 C ATOM 181 CG LYS A 117 -10.573 -6.013 13.534 1.00 51.81 C ATOM 182 CD LYS A 117 -9.082 -5.661 13.571 1.00 57.83 C ATOM 183 CE LYS A 117 -8.388 -6.116 14.847 1.00 63.65 C ATOM 184 NZ LYS A 117 -8.663 -5.207 16.017 1.00 69.15 N ATOM 185 N ILE A 118 -11.578 -9.365 11.759 1.00 36.12 N ATOM 186 CA ILE A 118 -11.899 -10.686 12.330 1.00 34.29 C ATOM 187 C ILE A 118 -10.823 -11.683 11.937 1.00 34.24 C ATOM 188 O ILE A 118 -10.304 -12.438 12.775 1.00 32.91 O ATOM 189 CB ILE A 118 -13.226 -11.147 11.792 1.00 34.32 C ATOM 190 CG1 ILE A 118 -14.342 -10.362 12.459 1.00 33.01 C ATOM 191 CG2 ILE A 118 -13.426 -12.618 12.044 1.00 30.28 C ATOM 192 CD1 ILE A 118 -15.699 -10.631 11.832 1.00 31.55 C ATOM 193 N LEU A 119 -10.469 -11.669 10.680 1.00 35.94 N ATOM 194 CA LEU A 119 -9.476 -12.605 10.181 1.00 38.32 C ATOM 195 C LEU A 119 -8.123 -12.403 10.866 1.00 38.25 C ATOM 196 O LEU A 119 -7.444 -13.379 11.189 1.00 38.15 O ATOM 197 CB LEU A 119 -9.325 -12.474 8.695 1.00 40.38 C ATOM 198 CG LEU A 119 -10.489 -12.993 7.884 1.00 41.50 C ATOM 199 CD1 LEU A 119 -10.261 -12.767 6.426 1.00 46.99 C ATOM 200 CD2 LEU A 119 -10.766 -14.493 8.147 1.00 43.88 C ATOM 201 N GLN A 120 -7.764 -11.157 11.094 1.00 40.20 N ATOM 202 CA GLN A 120 -6.508 -10.820 11.748 1.00 42.28 C ATOM 203 C GLN A 120 -6.492 -11.347 13.166 1.00 39.65 C ATOM 204 O GLN A 120 -5.541 -11.936 13.591 1.00 40.43 O ATOM 205 CB GLN A 120 -6.304 -9.307 11.774 1.00 43.41 C ATOM 206 CG GLN A 120 -5.135 -8.781 12.625 1.00 49.63 C ATOM 207 CD GLN A 120 -5.580 -8.085 13.926 1.00 51.07 C ATOM 208 OE1 GLN A 120 -6.198 -7.057 13.874 1.00 56.72 O ATOM 209 NE2 GLN A 120 -5.232 -8.668 15.097 1.00 50.75 N ATOM 210 N VAL A 121 -7.563 -11.058 13.903 1.00 38.23 N ATOM 211 CA VAL A 121 -7.708 -11.520 15.252 1.00 35.74 C ATOM 212 C VAL A 121 -7.541 -13.043 15.345 1.00 35.01 C ATOM 213 O VAL A 121 -6.740 -13.540 16.142 1.00 34.34 O ATOM 214 CB VAL A 121 -9.059 -11.055 15.902 1.00 35.20 C ATOM 215 CG1 VAL A 121 -9.217 -11.630 17.280 1.00 34.92 C ATOM 216 CG2 VAL A 121 -9.119 -9.558 16.007 1.00 38.98 C ATOM 217 N LEU A 122 -8.260 -13.766 14.519 1.00 33.29 N ATOM 218 CA LEU A 122 -8.226 -15.216 14.490 1.00 33.10 C ATOM 219 C LEU A 122 -6.867 -15.800 14.109 1.00 37.03 C ATOM 220 O LEU A 122 -6.401 -16.789 14.695 1.00 36.49 O ATOM 221 CB LEU A 122 -9.313 -15.765 13.562 1.00 34.68 C ATOM 222 CG LEU A 122 -10.777 -15.542 13.926 1.00 33.91 C ATOM 223 CD1 LEU A 122 -11.653 -16.081 12.844 1.00 31.80 C ATOM 224 CD2 LEU A 122 -11.204 -16.195 15.258 1.00 34.40 C ATOM 225 N SER A 123 -6.234 -15.166 13.136 1.00 37.39 N ATOM 226 CA SER A 123 -4.919 -15.597 12.639 1.00 37.90 C ATOM 227 C SER A 123 -3.838 -15.365 13.681 1.00 38.74 C ATOM 228 O SER A 123 -3.064 -16.249 13.984 1.00 41.69 O ATOM 229 CB SER A 123 -4.623 -14.782 11.388 1.00 40.41 C ATOM 230 OG SER A 123 -5.436 -15.178 10.315 1.00 40.01 O ATOM 231 N ASP A 124 -3.825 -14.171 14.271 1.00 38.89 N ATOM 232 CA ASP A 124 -2.901 -13.841 15.338 1.00 41.63 C ATOM 233 C ASP A 124 -3.055 -14.801 16.517 1.00 41.65 C ATOM 234 O ASP A 124 -2.054 -15.298 17.092 1.00 38.61 O ATOM 235 CB ASP A 124 -3.097 -12.408 15.808 1.00 41.86 C ATOM 236 CG ASP A 124 -2.546 -11.394 14.847 1.00 45.53 C ATOM 237 OD1 ASP A 124 -1.952 -11.813 13.834 1.00 49.64 O ATOM 238 OD2 ASP A 124 -2.661 -10.180 15.004 1.00 46.47 O ATOM 239 N ASP A 125 -4.286 -15.041 16.925 1.00 38.80 N ATOM 240 CA ASP A 125 -4.521 -15.976 18.025 1.00 38.30 C ATOM 241 C ASP A 125 -4.003 -17.338 17.666 1.00 42.73 C ATOM 242 O ASP A 125 -3.231 -17.974 18.438 1.00 43.30 O ATOM 243 CB ASP A 125 -6.015 -16.092 18.342 1.00 37.54 C ATOM 244 CG ASP A 125 -6.277 -16.919 19.598 1.00 35.31 C ATOM 245 OD1 ASP A 125 -6.117 -18.122 19.548 1.00 34.95 O ATOM 246 OD2 ASP A 125 -6.655 -16.383 20.675 1.00 38.09 O ATOM 247 N GLY A 126 -4.428 -17.849 16.513 1.00 43.16 N ATOM 248 CA GLY A 126 -3.947 -19.176 16.077 1.00 45.01 C ATOM 249 C GLY A 126 -4.807 -20.352 16.544 1.00 44.44 C ATOM 250 O GLY A 126 -4.746 -21.462 15.967 1.00 46.06 O ATOM 251 N GLY A 127 -5.608 -20.139 17.585 1.00 39.33 N ATOM 252 CA GLY A 127 -6.449 -21.188 18.096 1.00 37.55 C ATOM 253 C GLY A 127 -7.921 -20.769 18.172 1.00 38.06 C ATOM 254 O GLY A 127 -8.316 -19.768 17.616 1.00 33.69 O ATOM 255 N PRO A 128 -8.718 -21.578 18.840 1.00 40.57 N ATOM 256 CA PRO A 128 -10.153 -21.351 18.968 1.00 38.99 C ATOM 257 C PRO A 128 -10.393 -20.107 19.817 1.00 37.94 C ATOM 258 O PRO A 128 -9.816 -19.973 20.900 1.00 35.54 O ATOM 259 CB PRO A 128 -10.662 -22.612 19.643 1.00 41.59 C ATOM 260 CG PRO A 128 -9.527 -23.642 19.489 1.00 42.42 C ATOM 261 CD PRO A 128 -8.290 -22.884 19.441 1.00 42.23 C ATOM 262 N VAL A 129 -11.191 -19.190 19.254 1.00 32.88 N ATOM 263 CA VAL A 129 -11.476 -17.921 19.904 1.00 32.28 C ATOM 264 C VAL A 129 -12.957 -17.800 20.164 1.00 32.54 C ATOM 265 O VAL A 129 -13.787 -18.067 19.283 1.00 31.38 O ATOM 266 CB VAL A 129 -10.986 -16.760 19.016 1.00 30.27 C ATOM 267 CG1 VAL A 129 -11.253 -15.373 19.692 1.00 29.47 C ATOM 268 CG2 VAL A 129 -9.506 -16.903 18.669 1.00 34.09 C ATOM 269 N LYS A 130 -13.311 -17.426 21.386 1.00 31.77 N ATOM 270 CA LYS A 130 -14.707 -17.258 21.769 1.00 34.15 C ATOM 271 C LYS A 130 -15.313 -15.971 21.211 1.00 32.77 C ATOM 272 O LYS A 130 -14.594 -14.965 21.083 1.00 32.56 O ATOM 273 CB LYS A 130 -14.803 -17.223 23.269 1.00 35.87 C ATOM 274 CG LYS A 130 -14.492 -18.585 23.966 1.00 42.87 C ATOM 275 CD LYS A 130 -15.555 -19.571 23.585 1.00 50.72 C ATOM 276 CE LYS A 130 -15.775 -20.638 24.609 1.00 55.73 C ATOM 277 NZ LYS A 130 -14.911 -21.828 24.388 1.00 56.95 N ATOM 278 N ILE A 131 -16.599 -15.982 20.914 1.00 33.39 N ATOM 279 CA ILE A 131 -17.286 -14.797 20.365 1.00 31.29 C ATOM 280 C ILE A 131 -17.073 -13.627 21.262 1.00 31.32 C ATOM 281 O ILE A 131 -16.813 -12.516 20.785 1.00 33.07 O ATOM 282 CB ILE A 131 -18.779 -15.063 20.067 1.00 32.59 C ATOM 283 CG1 ILE A 131 -19.429 -13.852 19.383 1.00 33.56 C ATOM 284 CG2 ILE A 131 -19.556 -15.486 21.330 1.00 33.70 C ATOM 285 CD1 ILE A 131 -18.906 -13.546 18.018 1.00 35.09 C ATOM 286 N GLY A 132 -17.115 -13.847 22.571 1.00 30.91 N ATOM 287 CA GLY A 132 -16.937 -12.814 23.549 1.00 35.50 C ATOM 288 C GLY A 132 -15.554 -12.148 23.419 1.00 36.25 C ATOM 289 O GLY A 132 -15.406 -10.913 23.561 1.00 34.98 O ATOM 290 N GLN A 133 -14.564 -12.964 23.146 1.00 32.97 N ATOM 291 CA GLN A 133 -13.201 -12.425 22.969 1.00 34.43 C ATOM 292 C GLN A 133 -13.107 -11.615 21.700 1.00 33.24 C ATOM 293 O GLN A 133 -12.338 -10.627 21.654 1.00 33.45 O ATOM 294 CB GLN A 133 -12.206 -13.581 22.979 1.00 35.70 C ATOM 295 CG GLN A 133 -12.253 -14.401 24.262 1.00 35.05 C ATOM 296 CD GLN A 133 -11.272 -15.583 24.230 1.00 37.86 C ATOM 297 OE1 GLN A 133 -11.255 -16.326 23.273 1.00 31.93 O ATOM 298 NE2 GLN A 133 -10.477 -15.756 25.321 1.00 33.24 N ATOM 299 N LEU A 134 -13.832 -11.990 20.661 1.00 32.48 N ATOM 300 CA LEU A 134 -13.863 -11.200 19.419 1.00 32.79 C ATOM 301 C LEU A 134 -14.536 -9.827 19.619 1.00 33.04 C ATOM 302 O LEU A 134 -14.135 -8.852 19.014 1.00 32.79 O ATOM 303 CB LEU A 134 -14.531 -11.978 18.273 1.00 33.37 C ATOM 304 CG LEU A 134 -13.752 -13.188 17.752 1.00 33.01 C ATOM 305 CD1 LEU A 134 -14.651 -14.015 16.927 1.00 35.00 C ATOM 306 CD2 LEU A 134 -12.596 -12.781 16.900 1.00 34.94 C ATOM 307 N VAL A 135 -15.584 -9.775 20.440 1.00 35.82 N ATOM 308 CA VAL A 135 -16.199 -8.480 20.787 1.00 37.33 C ATOM 309 C VAL A 135 -15.182 -7.495 21.335 1.00 38.90 C ATOM 310 O VAL A 135 -15.110 -6.346 20.891 1.00 39.61 O ATOM 311 CB VAL A 135 -17.278 -8.629 21.877 1.00 40.16 C ATOM 312 CG1 VAL A 135 -17.841 -7.288 22.271 1.00 41.50 C ATOM 313 CG2 VAL A 135 -18.374 -9.568 21.417 1.00 37.57 C ATOM 314 N LYS A 136 -14.367 -7.934 22.310 1.00 37.35 N ATOM 315 CA LYS A 136 -13.367 -7.024 22.876 1.00 41.54 C ATOM 316 C LYS A 136 -12.369 -6.549 21.864 1.00 43.62 C ATOM 317 O LYS A 136 -11.943 -5.379 21.853 1.00 46.20 O ATOM 318 CB LYS A 136 -12.588 -7.697 24.037 1.00 41.55 C ATOM 319 CG LYS A 136 -13.451 -7.944 25.253 1.00 45.08 C ATOM 320 CD LYS A 136 -12.608 -8.388 26.464 1.00 49.71 C ATOM 321 CE LYS A 136 -13.416 -8.538 27.711 1.00 54.14 C ATOM 322 NZ LYS A 136 -14.477 -9.555 27.561 1.00 59.92 N ATOM 323 N LYS A 137 -11.949 -7.502 21.014 1.00 41.59 N ATOM 324 CA LYS A 137 -10.919 -7.271 20.043 1.00 43.02 C ATOM 325 C LYS A 137 -11.407 -6.460 18.845 1.00 44.31 C ATOM 326 O LYS A 137 -10.667 -5.628 18.329 1.00 45.42 O ATOM 327 CB LYS A 137 -10.370 -8.642 19.587 1.00 42.81 C ATOM 328 CG LYS A 137 -9.338 -9.253 20.523 1.00 46.34 C ATOM 329 CD LYS A 137 -7.961 -8.618 20.354 1.00 52.36 C ATOM 330 CE LYS A 137 -6.926 -9.230 21.275 1.00 58.67 C ATOM 331 NZ LYS A 137 -5.518 -8.822 20.869 1.00 59.98 N ATOM 332 N CYS A 138 -12.660 -6.694 18.417 1.00 43.25 N ATOM 333 CA CYS A 138 -13.233 -6.021 17.268 1.00 42.79 C ATOM 334 C CYS A 138 -14.133 -4.842 17.609 1.00 43.94 C ATOM 335 O CYS A 138 -14.467 -4.020 16.738 1.00 46.78 O ATOM 336 CB CYS A 138 -14.028 -7.013 16.415 1.00 40.74 C ATOM 337 SG CYS A 138 -13.023 -8.401 15.839 1.00 37.83 S ATOM 338 N GLN A 139 -14.558 -4.752 18.845 1.00 47.47 N ATOM 339 CA GLN A 139 -15.328 -3.576 19.313 1.00 49.50 C ATOM 340 C GLN A 139 -16.636 -3.346 18.567 1.00 48.95 C ATOM 341 O GLN A 139 -17.013 -2.196 18.240 1.00 51.05 O ATOM 342 CB GLN A 139 -14.411 -2.343 19.310 1.00 50.94 C ATOM 343 CG GLN A 139 -13.281 -2.523 20.327 1.00 54.68 C ATOM 344 CD GLN A 139 -12.205 -1.461 20.257 1.00 62.77 C ATOM 345 OE1 GLN A 139 -11.163 -1.586 20.936 1.00 64.09 O ATOM 346 NE2 GLN A 139 -12.441 -0.417 19.454 1.00 66.17 N ATOM 347 N VAL A 140 -17.350 -4.442 18.324 1.00 45.61 N ATOM 348 CA VAL A 140 -18.637 -4.461 17.719 1.00 47.65 C ATOM 349 C VAL A 140 -19.379 -5.562 18.434 1.00 46.62 C ATOM 350 O VAL A 140 -18.781 -6.484 19.014 1.00 43.79 O ATOM 351 CB VAL A 140 -18.606 -4.737 16.180 1.00 47.09 C ATOM 352 CG1 VAL A 140 -17.734 -3.695 15.491 1.00 48.77 C ATOM 353 CG2 VAL A 140 -18.119 -6.131 15.951 1.00 47.98 C ATOM 354 N PRO A 141 -20.681 -5.460 18.381 1.00 47.88 N ATOM 355 CA PRO A 141 -21.605 -6.405 19.007 1.00 48.21 C ATOM 356 C PRO A 141 -21.555 -7.780 18.433 1.00 43.79 C ATOM 357 O PRO A 141 -21.181 -7.993 17.283 1.00 46.85 O ATOM 358 CB PRO A 141 -22.970 -5.779 18.656 1.00 49.62 C ATOM 359 CG PRO A 141 -22.651 -4.403 18.471 1.00 51.87 C ATOM 360 CD PRO A 141 -21.415 -4.358 17.744 1.00 49.98 C ATOM 361 N LYS A 142 -21.959 -8.724 19.248 1.00 43.03 N ATOM 362 CA LYS A 142 -21.920 -10.152 18.885 1.00 42.67 C ATOM 363 C LYS A 142 -22.718 -10.450 17.613 1.00 42.30 C ATOM 364 O LYS A 142 -22.265 -11.190 16.734 1.00 37.11 O ATOM 365 CB LYS A 142 -22.488 -10.933 20.040 1.00 43.64 C ATOM 366 CG LYS A 142 -22.488 -12.422 19.870 1.00 46.82 C ATOM 367 N LYS A 143 -23.949 -9.914 17.548 1.00 42.18 N ATOM 368 CA LYS A 143 -24.788 -10.128 16.364 1.00 42.83 C ATOM 369 C LYS A 143 -24.034 -9.721 15.100 1.00 41.60 C ATOM 370 O LYS A 143 -24.021 -10.440 14.100 1.00 40.86 O ATOM 371 CB LYS A 143 -26.095 -9.313 16.514 1.00 44.57 C ATOM 372 CG LYS A 143 -27.166 -9.579 15.413 1.00 50.88 C ATOM 373 CD LYS A 143 -28.330 -8.458 15.457 1.00 55.24 C ATOM 374 CE LYS A 143 -29.702 -8.850 14.848 1.00 64.27 C ATOM 375 NZ LYS A 143 -30.863 -9.047 15.903 1.00 59.68 N ATOM 376 N THR A 144 -23.437 -8.547 15.122 1.00 41.73 N ATOM 377 CA THR A 144 -22.687 -8.062 13.970 1.00 43.42 C ATOM 378 C THR A 144 -21.543 -8.975 13.589 1.00 39.36 C ATOM 379 O THR A 144 -21.283 -9.202 12.430 1.00 37.97 O ATOM 380 CB THR A 144 -22.123 -6.686 14.286 1.00 45.00 C ATOM 381 OG1 THR A 144 -23.224 -5.800 14.576 1.00 49.48 O ATOM 382 CG2 THR A 144 -21.462 -6.072 13.071 1.00 45.73 C ATOM 383 N LEU A 145 -20.847 -9.504 14.591 1.00 38.12 N ATOM 384 CA LEU A 145 -19.763 -10.434 14.337 1.00 37.20 C ATOM 385 C LEU A 145 -20.274 -11.700 13.718 1.00 36.06 C ATOM 386 O LEU A 145 -19.706 -12.207 12.758 1.00 36.40 O ATOM 387 CB LEU A 145 -19.040 -10.791 15.632 1.00 36.63 C ATOM 388 CG LEU A 145 -18.108 -9.672 16.139 1.00 37.05 C ATOM 389 CD1 LEU A 145 -17.556 -10.082 17.524 1.00 36.18 C ATOM 390 CD2 LEU A 145 -17.021 -9.329 15.181 1.00 39.41 C ATOM 391 N ASN A 146 -21.348 -12.226 14.279 1.00 34.45 N ATOM 392 CA ASN A 146 -21.875 -13.499 13.794 1.00 35.16 C ATOM 393 C ASN A 146 -22.378 -13.421 12.363 1.00 34.63 C ATOM 394 O ASN A 146 -22.186 -14.342 11.603 1.00 33.85 O ATOM 395 CB ASN A 146 -22.944 -14.059 14.741 1.00 35.36 C ATOM 396 CG ASN A 146 -22.333 -14.743 15.943 1.00 36.77 C ATOM 397 OD1 ASN A 146 -21.281 -15.336 15.849 1.00 38.10 O ATOM 398 ND2 ASN A 146 -23.032 -14.651 17.098 1.00 35.96 N ATOM 399 N GLN A 147 -22.956 -12.282 11.989 1.00 36.56 N ATOM 400 CA GLN A 147 -23.392 -12.155 10.587 1.00 38.87 C ATOM 401 C GLN A 147 -22.185 -12.405 9.646 1.00 37.94 C ATOM 402 O GLN A 147 -22.281 -13.099 8.652 1.00 38.57 O ATOM 403 CB GLN A 147 -24.002 -10.790 10.312 1.00 41.44 C ATOM 404 CG GLN A 147 -25.198 -10.406 11.199 1.00 43.96 C ATOM 405 CD GLN A 147 -25.620 -8.954 10.995 1.00 47.54 C ATOM 406 OE1 GLN A 147 -24.786 -8.037 11.043 1.00 51.16 O ATOM 407 NE2 GLN A 147 -26.916 -8.731 10.799 1.00 47.42 N ATOM 408 N VAL A 148 -21.047 -11.811 9.967 1.00 38.74 N ATOM 409 CA VAL A 148 -19.823 -11.966 9.173 1.00 39.07 C ATOM 410 C VAL A 148 -19.211 -13.355 9.342 1.00 38.30 C ATOM 411 O VAL A 148 -18.893 -14.037 8.364 1.00 37.65 O ATOM 412 CB VAL A 148 -18.759 -10.912 9.554 1.00 39.76 C ATOM 413 CG1 VAL A 148 -17.469 -11.090 8.664 1.00 40.33 C ATOM 414 CG2 VAL A 148 -19.289 -9.533 9.424 1.00 41.43 C ATOM 415 N LEU A 149 -19.081 -13.807 10.599 1.00 35.46 N ATOM 416 CA LEU A 149 -18.522 -15.134 10.881 1.00 34.28 C ATOM 417 C LEU A 149 -19.211 -16.250 10.164 1.00 35.24 C ATOM 418 O LEU A 149 -18.563 -17.105 9.555 1.00 36.10 O ATOM 419 CB LEU A 149 -18.593 -15.435 12.368 1.00 33.19 C ATOM 420 CG LEU A 149 -17.534 -14.703 13.205 1.00 33.62 C ATOM 421 CD1 LEU A 149 -17.847 -14.787 14.662 1.00 33.96 C ATOM 422 CD2 LEU A 149 -16.121 -15.274 12.905 1.00 34.24 C ATOM 423 N TYR A 150 -20.555 -16.259 10.200 1.00 36.66 N ATOM 424 CA TYR A 150 -21.279 -17.332 9.554 1.00 37.01 C ATOM 425 C TYR A 150 -21.143 -17.241 8.028 1.00 40.67 C ATOM 426 O TYR A 150 -21.157 -18.253 7.320 1.00 41.17 O ATOM 427 CB TYR A 150 -22.734 -17.395 9.991 1.00 38.30 C ATOM 428 CG TYR A 150 -22.860 -18.085 11.343 1.00 35.27 C ATOM 429 CD1 TYR A 150 -22.840 -19.462 11.422 1.00 37.83 C ATOM 430 CD2 TYR A 150 -22.896 -17.355 12.507 1.00 34.08 C ATOM 431 CE1 TYR A 150 -22.888 -20.118 12.647 1.00 39.78 C ATOM 432 CE2 TYR A 150 -22.978 -18.013 13.756 1.00 35.29 C ATOM 433 CZ TYR A 150 -22.970 -19.381 13.809 1.00 35.56 C ATOM 434 OH TYR A 150 -23.036 -20.021 15.014 1.00 41.58 O ATOM 435 N ARG A 151 -21.003 -16.034 7.541 1.00 42.13 N ATOM 436 CA ARG A 151 -20.790 -15.885 6.119 1.00 45.55 C ATOM 437 C ARG A 151 -19.413 -16.463 5.766 1.00 44.32 C ATOM 438 O ARG A 151 -19.290 -17.325 4.902 1.00 44.17 O ATOM 439 CB ARG A 151 -20.871 -14.439 5.695 1.00 45.79 C ATOM 440 CG ARG A 151 -20.960 -14.397 4.212 1.00 51.78 C ATOM 441 CD ARG A 151 -20.868 -13.058 3.552 1.00 57.30 C ATOM 442 NE ARG A 151 -20.226 -11.963 4.245 1.00 58.77 N ATOM 443 CZ ARG A 151 -18.929 -11.666 4.188 1.00 64.63 C ATOM 444 NH1 ARG A 151 -18.484 -10.582 4.819 1.00 65.91 N ATOM 445 NH2 ARG A 151 -18.065 -12.434 3.530 1.00 66.45 N ATOM 446 N LEU A 152 -18.396 -16.031 6.509 1.00 44.21 N ATOM 447 CA LEU A 152 -17.042 -16.534 6.293 1.00 44.59 C ATOM 448 C LEU A 152 -17.026 -18.054 6.365 1.00 46.04 C ATOM 449 O LEU A 152 -16.346 -18.712 5.561 1.00 47.11 O ATOM 450 CB LEU A 152 -16.021 -15.920 7.261 1.00 44.19 C ATOM 451 CG LEU A 152 -15.768 -14.429 7.107 1.00 44.45 C ATOM 452 CD1 LEU A 152 -14.843 -13.936 8.272 1.00 46.49 C ATOM 453 CD2 LEU A 152 -15.141 -14.135 5.771 1.00 46.91 C ATOM 454 N LYS A 153 -17.800 -18.622 7.278 1.00 44.73 N ATOM 455 CA LYS A 153 -17.841 -20.055 7.455 1.00 47.99 C ATOM 456 C LYS A 153 -18.425 -20.762 6.223 1.00 50.89 C ATOM 457 O LYS A 153 -17.943 -21.808 5.812 1.00 53.11 O ATOM 458 CB LYS A 153 -18.606 -20.476 8.709 1.00 47.14 C ATOM 459 CG LYS A 153 -19.086 -21.903 8.663 1.00 51.50 C ATOM 460 CD LYS A 153 -19.545 -22.441 9.988 1.00 54.02 C ATOM 461 CE LYS A 153 -20.339 -23.730 9.791 1.00 58.95 C ATOM 462 NZ LYS A 153 -19.849 -24.598 8.627 1.00 60.56 N ATOM 463 N LYS A 154 -19.446 -20.168 5.648 1.00 53.48 N ATOM 464 CA LYS A 154 -20.105 -20.732 4.492 1.00 57.00 C ATOM 465 C LYS A 154 -19.159 -20.638 3.292 1.00 59.38 C ATOM 466 O LYS A 154 -19.326 -21.343 2.293 1.00 60.75 O ATOM 467 CB LYS A 154 -21.359 -19.954 4.192 1.00 58.67 C ATOM 468 CG LYS A 154 -22.289 -20.622 3.212 1.00 64.72 C ATOM 469 CD LYS A 154 -23.452 -19.718 2.915 1.00 71.26 C ATOM 470 CE LYS A 154 -23.593 -19.490 1.436 1.00 77.48 C ATOM 471 NZ LYS A 154 -23.783 -20.769 0.659 1.00 81.54 N ATOM 472 N GLU A 155 -18.190 -19.746 3.406 1.00 60.68 N ATOM 473 CA GLU A 155 -17.166 -19.557 2.401 1.00 62.93 C ATOM 474 C GLU A 155 -15.941 -20.412 2.702 1.00 63.86 C ATOM 475 O GLU A 155 -14.914 -20.232 2.070 1.00 64.40 O ATOM 476 CB GLU A 155 -16.761 -18.073 2.325 1.00 62.39 C ATOM 477 CG GLU A 155 -17.826 -17.107 1.834 1.00 63.94 C ATOM 478 CD GLU A 155 -17.387 -15.647 1.897 1.00 63.48 C ATOM 479 OE1 GLU A 155 -16.190 -15.396 2.073 1.00 69.42 O ATOM 480 OE2 GLU A 155 -18.230 -14.733 1.764 1.00 65.21 O ATOM 481 N ASP A 156 -16.037 -21.332 3.662 1.00 64.23 N ATOM 482 CA ASP A 156 -14.900 -22.189 4.047 1.00 64.96 C ATOM 483 C ASP A 156 -13.659 -21.370 4.479 1.00 62.79 C ATOM 484 O ASP A 156 -12.531 -21.835 4.366 1.00 63.16 O ATOM 485 CB ASP A 156 -14.515 -23.154 2.908 1.00 67.28 C ATOM 486 CG ASP A 156 -15.394 -24.396 2.850 1.00 72.45 C ATOM 487 OD1 ASP A 156 -16.167 -24.673 3.803 1.00 74.24 O ATOM 488 OD2 ASP A 156 -15.379 -25.174 1.871 1.00 80.77 O ATOM 489 N ARG A 157 -13.879 -20.177 5.008 1.00 59.60 N ATOM 490 CA ARG A 157 -12.783 -19.281 5.415 1.00 56.63 C ATOM 491 C ARG A 157 -12.521 -19.176 6.914 1.00 52.87 C ATOM 492 O ARG A 157 -11.539 -18.542 7.307 1.00 49.38 O ATOM 493 CB ARG A 157 -13.073 -17.907 4.880 1.00 56.77 C ATOM 494 CG ARG A 157 -13.346 -17.944 3.416 1.00 61.53 C ATOM 495 CD ARG A 157 -12.358 -17.187 2.602 1.00 68.76 C ATOM 496 NE ARG A 157 -12.675 -15.764 2.670 1.00 70.92 N ATOM 497 CZ ARG A 157 -11.838 -14.845 3.112 1.00 72.06 C ATOM 498 NH1 ARG A 157 -10.591 -15.195 3.535 1.00 68.78 N ATOM 499 NH2 ARG A 157 -12.230 -13.575 3.103 1.00 69.26 N ATOM 500 N VAL A 158 -13.445 -19.733 7.726 1.00 48.91 N ATOM 501 CA VAL A 158 -13.255 -19.905 9.132 1.00 46.42 C ATOM 502 C VAL A 158 -13.994 -21.168 9.454 1.00 48.54 C ATOM 503 O VAL A 158 -14.708 -21.696 8.614 1.00 47.80 O ATOM 504 CB VAL A 158 -13.811 -18.706 9.940 1.00 44.16 C ATOM 505 CG1 VAL A 158 -12.962 -17.475 9.630 1.00 39.24 C ATOM 506 CG2 VAL A 158 -15.216 -18.475 9.592 1.00 41.53 C ATOM 507 N SER A 159 -13.830 -21.676 10.665 1.00 48.20 N ATOM 508 CA SER A 159 -14.518 -22.872 11.110 1.00 50.63 C ATOM 509 C SER A 159 -14.968 -22.612 12.502 1.00 48.50 C ATOM 510 O SER A 159 -14.472 -21.680 13.147 1.00 46.04 O ATOM 511 CB SER A 159 -13.570 -24.086 11.113 1.00 53.05 C ATOM 512 OG SER A 159 -12.543 -23.845 12.040 1.00 59.07 O ATOM 513 N SER A 160 -15.904 -23.423 12.963 1.00 49.73 N ATOM 514 CA SER A 160 -16.421 -23.330 14.294 1.00 49.79 C ATOM 515 C SER A 160 -16.289 -24.706 14.872 1.00 51.80 C ATOM 516 O SER A 160 -17.229 -25.519 14.750 1.00 52.87 O ATOM 517 CB SER A 160 -17.889 -22.920 14.250 1.00 50.47 C ATOM 518 OG SER A 160 -18.322 -22.453 15.496 1.00 50.43 O ATOM 519 N PRO A 161 -15.149 -24.997 15.492 1.00 51.53 N ATOM 520 CA PRO A 161 -14.920 -26.324 16.062 1.00 54.58 C ATOM 521 C PRO A 161 -15.796 -26.581 17.262 1.00 54.51 C ATOM 522 O PRO A 161 -15.957 -27.708 17.644 1.00 55.91 O ATOM 523 CB PRO A 161 -13.443 -26.270 16.486 1.00 52.82 C ATOM 524 CG PRO A 161 -13.249 -24.852 16.793 1.00 52.43 C ATOM 525 CD PRO A 161 -13.983 -24.141 15.677 1.00 50.72 C ATOM 526 N GLU A 162 -16.296 -25.510 17.851 1.00 54.11 N ATOM 527 CA GLU A 162 -17.224 -25.558 18.964 1.00 56.02 C ATOM 528 C GLU A 162 -18.222 -24.447 18.808 1.00 54.01 C ATOM 529 O GLU A 162 -17.985 -23.487 18.130 1.00 50.50 O ATOM 530 CB GLU A 162 -16.511 -25.230 20.244 1.00 56.20 C ATOM 531 CG GLU A 162 -16.024 -26.371 21.053 1.00 63.46 C ATOM 532 CD GLU A 162 -15.394 -25.875 22.328 1.00 66.89 C ATOM 533 OE1 GLU A 162 -16.081 -25.140 23.054 1.00 70.67 O ATOM 534 OE2 GLU A 162 -14.215 -26.197 22.579 1.00 71.28 O ATOM 535 N PRO A 163 -19.328 -24.550 19.520 1.00 55.47 N ATOM 536 CA PRO A 163 -20.366 -23.526 19.424 1.00 52.54 C ATOM 537 C PRO A 163 -19.868 -22.173 19.946 1.00 46.57 C ATOM 538 O PRO A 163 -19.242 -22.081 20.995 1.00 43.91 O ATOM 539 CB PRO A 163 -21.460 -24.086 20.306 1.00 56.45 C ATOM 540 CG PRO A 163 -20.728 -24.924 21.268 1.00 58.31 C ATOM 541 CD PRO A 163 -19.686 -25.614 20.467 1.00 57.62 C ATOM 542 N ALA A 164 -20.153 -21.140 19.160 1.00 42.20 N ATOM 543 CA ALA A 164 -19.756 -19.762 19.456 1.00 38.85 C ATOM 544 C ALA A 164 -18.252 -19.668 19.636 1.00 36.77 C ATOM 545 O ALA A 164 -17.768 -18.795 20.349 1.00 35.64 O ATOM 546 CB ALA A 164 -20.469 -19.212 20.634 1.00 39.96 C ATOM 547 N THR A 165 -17.534 -20.580 19.014 1.00 35.99 N ATOM 548 CA THR A 165 -16.061 -20.562 19.054 1.00 35.35 C ATOM 549 C THR A 165 -15.541 -20.627 17.648 1.00 35.43 C ATOM 550 O THR A 165 -16.078 -21.379 16.822 1.00 34.55 O ATOM 551 CB THR A 165 -15.549 -21.763 19.845 1.00 38.24 C ATOM 552 OG1 THR A 165 -16.178 -21.750 21.142 1.00 38.53 O ATOM 553 CG2 THR A 165 -14.089 -21.601 20.141 1.00 37.58 C ATOM 554 N TRP A 166 -14.498 -19.813 17.327 1.00 32.62 N ATOM 555 CA TRP A 166 -14.096 -19.659 15.947 1.00 33.06 C ATOM 556 C TRP A 166 -12.596 -19.743 15.765 1.00 33.77 C ATOM 557 O TRP A 166 -11.833 -19.374 16.652 1.00 33.69 O ATOM 558 CB TRP A 166 -14.604 -18.303 15.432 1.00 33.42 C ATOM 559 CG TRP A 166 -16.121 -18.207 15.512 1.00 31.99 C ATOM 560 CD1 TRP A 166 -16.861 -17.794 16.573 1.00 34.63 C ATOM 561 CD2 TRP A 166 -17.045 -18.656 14.536 1.00 35.87 C ATOM 562 NE1 TRP A 166 -18.199 -17.912 16.299 1.00 33.57 N ATOM 563 CE2 TRP A 166 -18.345 -18.436 15.057 1.00 36.86 C ATOM 564 CE3 TRP A 166 -16.932 -19.146 13.224 1.00 35.36 C ATOM 565 CZ2 TRP A 166 -19.524 -18.708 14.306 1.00 39.91 C ATOM 566 CZ3 TRP A 166 -18.089 -19.428 12.529 1.00 38.42 C ATOM 567 CH2 TRP A 166 -19.354 -19.237 13.079 1.00 39.92 C ATOM 568 N SER A 167 -12.186 -20.280 14.620 1.00 34.52 N ATOM 569 CA SER A 167 -10.764 -20.346 14.321 1.00 38.65 C ATOM 570 C SER A 167 -10.535 -20.187 12.814 1.00 40.16 C ATOM 571 O SER A 167 -11.462 -20.261 12.037 1.00 42.23 O ATOM 572 CB SER A 167 -10.164 -21.691 14.798 1.00 40.13 C ATOM 573 OG SER A 167 -10.725 -22.739 14.071 1.00 43.98 O ATOM 574 N ILE A 168 -9.289 -20.092 12.416 1.00 45.41 N ATOM 575 CA ILE A 168 -8.982 -19.888 11.017 1.00 47.33 C ATOM 576 C ILE A 168 -9.115 -21.216 10.257 1.00 48.77 C ATOM 577 O ILE A 168 -8.676 -22.275 10.718 1.00 48.27 O ATOM 578 CB ILE A 168 -7.553 -19.351 10.812 1.00 48.75 C ATOM 579 CG1 ILE A 168 -7.453 -17.830 10.884 1.00 51.99 C ATOM 580 CG2 ILE A 168 -7.091 -19.750 9.409 1.00 52.58 C ATOM 581 CD1 ILE A 168 -8.017 -17.060 9.643 1.00 48.55 C ATOM 582 N GLY A 169 -9.691 -21.120 9.071 1.00 49.93 N ATOM 583 CA GLY A 169 -9.919 -22.254 8.219 1.00 53.51 C ATOM 584 C GLY A 169 -11.303 -22.839 8.397 1.00 55.16 C ATOM 585 O GLY A 169 -11.595 -23.367 9.489 1.00 57.12 O TER 586 GLY A 169 HETATM 587 O HOH B 304 -28.323 -21.168 10.200 1.00 45.10 O HETATM 588 O HOH B 305 -25.595 -17.419 25.965 1.00 45.56 O HETATM 589 O HOH B 306 -26.754 -14.952 21.861 1.00 42.75 O HETATM 590 O HOH B 307 -25.517 -17.503 21.475 1.00 35.24 O HETATM 591 O HOH B 321 -28.020 -15.107 5.706 1.00 50.22 O HETATM 592 O HOH B 329 -22.866 -15.467 20.028 1.00 48.22 O HETATM 593 O HOH B 332 -30.821 -13.133 14.629 1.00 39.92 O HETATM 594 O HOH B 333 -26.281 -19.648 9.126 1.00 58.77 O HETATM 595 O HOH B 340 -29.968 -25.498 27.654 1.00 57.72 O HETATM 596 O HOH B 342 -37.173 -13.803 11.111 1.00 54.26 O HETATM 597 O HOH B 343 -37.789 -14.385 8.192 1.00 48.92 O HETATM 598 O HOH B 344 -23.970 -17.686 23.687 1.00 41.73 O HETATM 599 O HOH B 345 -18.976 -19.049 23.750 1.00 57.95 O HETATM 600 O HOH B 349 -31.457 -9.719 12.536 1.00 55.23 O HETATM 601 O HOH B 354 -26.730 -10.313 7.912 1.00 55.62 O HETATM 602 O HOH B 355 -24.244 -25.220 21.962 1.00 59.73 O HETATM 603 O HOH B 361 -31.309 -26.130 21.077 1.00 70.18 O HETATM 604 O HOH B 362 -34.515 -29.328 16.531 1.00 84.01 O HETATM 605 O HOH B 373 -29.786 -11.866 16.941 1.00 53.57 O HETATM 606 O HOH B 388 -39.795 -10.827 10.290 1.00 79.48 O HETATM 607 O HOH B 389 -37.986 -8.957 10.267 1.00 79.03 O HETATM 608 O HOH B 390 -26.890 -11.943 20.843 1.00 64.53 O HETATM 609 O HOH B 391 -31.803 -29.146 18.057 0.50 67.88 O HETATM 610 O HOH B 395 -34.490 -7.873 12.872 1.00 59.61 O HETATM 611 O HOH A 301 -7.853 -18.830 15.346 1.00 43.75 O HETATM 612 O HOH A 302 -4.370 -15.000 22.085 1.00 47.48 O HETATM 613 O HOH A 303 -20.583 -17.121 17.591 1.00 34.30 O HETATM 614 O HOH A 308 -5.995 -12.219 18.441 1.00 35.47 O HETATM 615 O HOH A 309 -7.631 -13.604 20.633 1.00 39.23 O HETATM 616 O HOH A 310 -7.157 -19.896 21.455 1.00 36.99 O HETATM 617 O HOH A 311 -10.254 -10.608 23.564 1.00 39.06 O HETATM 618 O HOH A 312 -22.557 -2.795 14.855 1.00 51.97 O HETATM 619 O HOH A 313 -22.369 -7.837 10.222 1.00 46.73 O HETATM 620 O HOH A 314 -7.410 -23.598 16.186 1.00 51.95 O HETATM 621 O HOH A 315 -3.725 -13.319 19.987 1.00 37.53 O HETATM 622 O HOH A 316 -5.113 -9.908 18.698 1.00 67.03 O HETATM 623 O HOH A 317 -24.334 -14.034 4.196 1.00 55.50 O HETATM 624 O HOH A 318 -8.920 -4.024 22.589 1.00 55.29 O HETATM 625 O HOH A 319 -8.816 -8.221 24.217 1.00 48.77 O HETATM 626 O HOH A 320 -26.786 -13.627 7.579 1.00 48.30 O HETATM 627 O HOH A 322 -8.456 -12.661 22.692 1.00 46.99 O HETATM 628 O HOH A 323 -1.321 -11.994 19.710 1.00 54.17 O HETATM 629 O HOH A 324 -16.181 -15.417 26.246 1.00 39.81 O HETATM 630 O HOH A 325 -22.038 -11.261 6.008 1.00 51.89 O HETATM 631 O HOH A 326 -17.996 -15.782 24.502 1.00 40.16 O HETATM 632 O HOH A 327 -14.106 -12.126 26.760 1.00 51.12 O HETATM 633 O HOH A 328 -22.544 -7.979 22.069 1.00 46.28 O HETATM 634 O HOH A 330 -9.253 -16.970 5.514 1.00 45.96 O HETATM 635 O HOH A 331 -20.943 -21.635 16.140 1.00 49.38 O HETATM 636 O HOH A 334 -17.176 -9.526 25.613 1.00 45.59 O HETATM 637 O HOH A 335 -15.337 -8.868 30.102 0.50 53.92 O HETATM 638 O HOH A 336 -15.725 -23.626 7.192 1.00 56.83 O HETATM 639 O HOH A 337 -18.319 -28.428 23.556 1.00 63.04 O HETATM 640 O HOH A 338 0.028 -13.524 18.046 0.50 81.10 O HETATM 641 O HOH A 339 -11.191 -19.365 23.998 0.50 50.92 O HETATM 642 O HOH A 341 -11.583 -26.980 3.183 1.00 60.25 O HETATM 643 O HOH A 346 -10.250 -25.529 14.521 1.00 76.79 O HETATM 644 O HOH A 347 -24.485 -16.710 5.995 1.00 58.51 O HETATM 645 O HOH A 348 -24.644 -14.849 8.059 1.00 52.53 O HETATM 646 O HOH A 350 -26.313 -17.513 8.993 1.00 51.18 O HETATM 647 O HOH A 351 -4.168 -6.414 18.363 1.00 69.76 O HETATM 648 O HOH A 352 -8.981 -25.628 8.031 1.00 59.67 O HETATM 649 O HOH A 353 -25.140 -19.463 5.659 1.00 74.29 O HETATM 650 O HOH A 356 -22.212 -10.514 1.666 1.00 70.40 O HETATM 651 O HOH A 357 -19.914 -10.691 0.653 1.00 70.82 O HETATM 652 O HOH A 358 -19.341 -3.114 11.679 1.00 67.41 O HETATM 653 O HOH A 359 -19.478 -0.662 7.791 1.00 65.84 O HETATM 654 O HOH A 360 -20.941 -1.297 9.848 1.00 69.39 O HETATM 655 O HOH A 363 -18.622 -17.806 27.343 1.00 54.02 O HETATM 656 O HOH A 364 -16.589 -1.903 2.379 1.00 74.42 O HETATM 657 O HOH A 365 -15.506 -1.137 5.278 1.00 69.82 O HETATM 658 O HOH A 366 -14.573 3.558 7.123 1.00 79.89 O HETATM 659 O HOH A 367 -16.587 -3.402 7.909 1.00 55.00 O HETATM 660 O HOH A 368 -19.618 -25.775 16.175 1.00 68.65 O HETATM 661 O HOH A 369 -10.759 0.843 7.650 1.00 72.33 O HETATM 662 O HOH A 370 -1.105 -8.699 14.011 1.00 72.91 O HETATM 663 O HOH A 371 -22.469 -20.586 7.858 1.00 58.53 O HETATM 664 O HOH A 372 -6.774 -8.526 7.676 1.00 56.83 O HETATM 665 O HOH A 374 -25.209 -5.350 12.720 1.00 58.69 O HETATM 666 O HOH A 375 -23.272 -2.333 11.460 1.00 69.81 O HETATM 667 O HOH A 376 -28.163 -5.832 10.724 1.00 69.27 O HETATM 668 O HOH A 377 -21.829 -8.483 7.292 1.00 70.40 O HETATM 669 O HOH A 378 -14.651 -5.996 2.751 1.00 56.17 O HETATM 670 O HOH A 379 -11.919 3.757 6.842 1.00 70.89 O HETATM 671 O HOH A 380 -13.097 -3.006 14.467 1.00 69.59 O HETATM 672 O HOH A 381 -21.925 -22.866 -0.719 1.00 72.59 O HETATM 673 O HOH A 382 -16.410 -6.209 6.673 1.00 59.27 O HETATM 674 O HOH A 383 -12.970 -2.800 11.234 1.00 69.31 O HETATM 675 O HOH A 384 -10.224 -0.843 12.008 1.00 67.76 O HETATM 676 O HOH A 385 -10.591 1.967 12.463 1.00 85.66 O HETATM 677 O HOH A 386 -8.069 0.871 11.998 1.00 85.02 O HETATM 678 O HOH A 387 -4.928 -24.653 17.384 1.00 65.42 O HETATM 679 O HOH A 392 -16.850 -30.206 17.114 1.00 92.31 O HETATM 680 O HOH A 393 -14.227 -26.084 8.668 1.00 59.74 O HETATM 681 O HOH A 394 -9.945 -25.196 10.635 1.00 67.87 O HETATM 682 O HOH A 396 -16.610 -25.565 11.723 1.00 76.30 O HETATM 683 O HOH A 397 -19.163 -22.985 23.962 1.00 75.91 O HETATM 684 O HOH A 398 -2.181 -8.951 18.355 1.00 65.42 O HETATM 685 O HOH A 399 -22.154 -23.899 6.029 0.50 75.78 O HETATM 686 O HOH A 400 -26.150 -4.262 16.553 1.00 79.39 O HETATM 687 O HOH A 401 -19.648 -8.405 5.673 1.00 59.15 O HETATM 688 O HOH A 402 -19.149 -30.460 18.984 1.00 69.43 O MASTER 334 0 0 3 3 0 0 6 686 2 0 7 END
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Related entries of code: 1j75
Entries with 90% protein sequence similarity cutoff in PDBbind
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Complexes with the same small molecule ligand
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Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
1j75
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Tumor Stroma and Activated Macrophage Protein DLM-1
Ligand Name
Z-DNA
EC.Number
E.C.-.-.-.-
Resolution
1.85(Å)
Affinity (Kd/Ki/IC50)
Kd=35nM
Release Year
2001
Protein/NA Sequence
Check fasta file
Primary Reference
Nature structural biology. (2001) 8, pp. 761-5
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q9QY24
Entrez Gene ID
NCBI Entrez Gene ID:
58203
ASD
Information of known allosteric effects of PDB entries
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