Browse entries in the PDBbind-CN Database
HEADER TRANSPORT PROTEIN/DNA 15-JUL-04 1U1M TITLE CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTA 7GU TITLE 2 GG); A HUMAN TELOMERIC REPEAT CONTAINING 7-DEAZA-GUANINE COMPND MOL_ID: 1; COMPND 2 MOLECULE: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(7GU)P*GP*G)-3'; COMPND 3 CHAIN: B; COMPND 4 ENGINEERED: YES; COMPND 5 MOL_ID: 2; COMPND 6 MOLECULE: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; COMPND 7 CHAIN: A; COMPND 8 SYNONYM: HELIX-DESTABILIZING PROTEIN, SINGLE-STRAND COMPND 9 BINDING PROTEIN, HNRNP CORE PROTEIN A1; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 OTHER_DETAILS: OLIGONUCLEOTIDE D(TTAGGGTTA(7GU)GG) BASED SOURCE 4 ON HUMAN TELOMERIC REPEAT D(TTAGGG)N; SOURCE 5 MOL_ID: 2; SOURCE 6 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 7 ORGANISM_COMMON: HUMAN; SOURCE 8 ORGANISM_TAXID: 9606; SOURCE 9 GENE: HNRPA1; SOURCE 10 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21(DE3); SOURCE 11 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 12 EXPRESSION_SYSTEM_STRAIN: BL21DE3; SOURCE 13 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 14 EXPRESSION_SYSTEM_PLASMID: PYS45 KEYWDS PROTEIN-DNA COMPLEX, UP1, HUMAN TELOMERIC REPEAT, HTR, TR2- KEYWDS 2 G(10)7GU, RRM, RNA RECOGNITION MOTIF, 7GU, 7-DEAZA-GUANINE, KEYWDS 3 HNRNP A1, TRANSPORT PROTEIN/DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR J.C.MYERS,Y.SHAMOO REVDAT 2 24-FEB-09 1U1M 1 VERSN REVDAT 1 21-SEP-04 1U1M 0 JRNL AUTH J.C.MYERS,Y.SHAMOO JRNL TITL HUMAN UP1 AS A MODEL FOR UNDERSTANDING PURINE JRNL TITL 2 RECOGNITION IN THE FAMILY OF PROTEINS CONTAINING JRNL TITL 3 THE RNA RECOGNITION MOTIF (RRM). JRNL REF J.MOL.BIOL. V. 342 743 2004 JRNL REFN ISSN 0022-2836 JRNL PMID 15342234 JRNL DOI 10.1016/J.JMB.2004.07.029 REMARK 1 REMARK 2 REMARK 2 RESOLUTION. 2.00 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : CNS 1.0 REMARK 3 AUTHORS : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE- REMARK 3 : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES, PANNU, REMARK 3 : READ,RICE,SIMONSON,WARREN REMARK 3 REMARK 3 REFINEMENT TARGET : ENGH & HUBER REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.00 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 19.84 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 DATA CUTOFF HIGH (ABS(F)) : 496017.760 REMARK 3 DATA CUTOFF LOW (ABS(F)) : 0.0000 REMARK 3 COMPLETENESS (WORKING+TEST) (%) : 96.4 REMARK 3 NUMBER OF REFLECTIONS : 15551 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING SET) : 0.241 REMARK 3 FREE R VALUE : 0.273 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.900 REMARK 3 FREE R VALUE TEST SET COUNT : 766 REMARK 3 ESTIMATED ERROR OF FREE R VALUE : 0.010 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 10 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.00 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.07 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 89.40 REMARK 3 REFLECTIONS IN BIN (WORKING SET) : 1328 REMARK 3 BIN R VALUE (WORKING SET) : 0.3490 REMARK 3 BIN FREE R VALUE : 0.4230 REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : 4.90 REMARK 3 BIN FREE R VALUE TEST SET COUNT : 68 REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : 0.051 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1466 REMARK 3 NUCLEIC ACID ATOMS : 231 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 114 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 26.80 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 35.80 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 4.98000 REMARK 3 B22 (A**2) : 4.98000 REMARK 3 B33 (A**2) : -9.95000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM LUZZATI PLOT (A) : 0.30 REMARK 3 ESD FROM SIGMAA (A) : 0.32 REMARK 3 LOW RESOLUTION CUTOFF (A) : 20.00 REMARK 3 REMARK 3 CROSS-VALIDATED ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM C-V LUZZATI PLOT (A) : 0.36 REMARK 3 ESD FROM C-V SIGMAA (A) : 0.38 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES. REMARK 3 BOND LENGTHS (A) : 0.006 REMARK 3 BOND ANGLES (DEGREES) : 1.20 REMARK 3 DIHEDRAL ANGLES (DEGREES) : 22.90 REMARK 3 IMPROPER ANGLES (DEGREES) : 1.74 REMARK 3 REMARK 3 ISOTROPIC THERMAL MODEL : RESTRAINED REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. RMS SIGMA REMARK 3 MAIN-CHAIN BOND (A**2) : 4.980 ; 1.500 REMARK 3 MAIN-CHAIN ANGLE (A**2) : 7.760 ; 2.000 REMARK 3 SIDE-CHAIN BOND (A**2) : 8.330 ; 2.000 REMARK 3 SIDE-CHAIN ANGLE (A**2) : 11.920; 2.500 REMARK 3 REMARK 3 BULK SOLVENT MODELING. REMARK 3 METHOD USED : FLAT MODEL REMARK 3 KSOL : 0.36 REMARK 3 BSOL : 45.40 REMARK 3 REMARK 3 NCS MODEL : NULL REMARK 3 REMARK 3 NCS RESTRAINTS. RMS SIGMA/WEIGHT REMARK 3 GROUP 1 POSITIONAL (A) : NULL ; NULL REMARK 3 GROUP 1 B-FACTOR (A**2) : NULL ; NULL REMARK 3 REMARK 3 PARAMETER FILE 1 : PROTEIN_REP.PARAM REMARK 3 PARAMETER FILE 2 : 010404.PARAM REMARK 3 PARAMETER FILE 3 : WATER_REP.PARAM REMARK 3 PARAMETER FILE 4 : NULL REMARK 3 TOPOLOGY FILE 1 : PROTEIN.TOP REMARK 3 TOPOLOGY FILE 2 : 010404.TOP REMARK 3 TOPOLOGY FILE 3 : WATER.TOP REMARK 3 TOPOLOGY FILE 4 : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 1U1M COMPLIES WITH FORMAT V. 3.15, 01-DEC-08 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 11-AUG-04. REMARK 100 THE RCSB ID CODE IS RCSB023132. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 04-JAN-02 REMARK 200 TEMPERATURE (KELVIN) : 103.0 REMARK 200 PH : 8.1 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : N REMARK 200 RADIATION SOURCE : ROTATING ANODE REMARK 200 BEAMLINE : NULL REMARK 200 X-RAY GENERATOR MODEL : RIGAKU RUH3R REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.5418 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : OSMIC MIRRORS REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : RIGAKU JUPITER REMARK 200 INTENSITY-INTEGRATION SOFTWARE : CRYSTALCLEAR (MSC/RIGAKU) REMARK 200 DATA SCALING SOFTWARE : D*TREK REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 15551 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.000 REMARK 200 RESOLUTION RANGE LOW (A) : 20.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 0.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 96.4 REMARK 200 DATA REDUNDANCY : 3.080 REMARK 200 R MERGE (I) : 0.08100 REMARK 200 R SYM (I) : 0.08100 REMARK 200
FOR THE DATA SET : 7.9000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.00 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.07 REMARK 200 COMPLETENESS FOR SHELL (%) : 89.4 REMARK 200 DATA REDUNDANCY IN SHELL : 2.41 REMARK 200 R MERGE FOR SHELL (I) : 0.43500 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200
FOR SHELL : 1.600 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: CNS REMARK 200 STARTING MODEL: PDB ENTRY 2UP1 REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 44.51 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.26 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: AMMONIUM PHOSPHATE, GLYCEROL, TRIS, REMARK 280 SODIUM CHLORIDE, MES, EDTA, BETA-MERCAPTOETHANOL , PH 8.1, REMARK 280 VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 283.0K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 43 21 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y+1/2,X+1/2,Z+3/4 REMARK 290 4555 Y+1/2,-X+1/2,Z+1/4 REMARK 290 5555 -X+1/2,Y+1/2,-Z+3/4 REMARK 290 6555 X+1/2,-Y+1/2,-Z+1/4 REMARK 290 7555 Y,X,-Z REMARK 290 8555 -Y,-X,-Z+1/2 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 86.21350 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 25.42000 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 25.42000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 129.32025 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 25.42000 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 25.42000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 43.10675 REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 25.42000 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 25.42000 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 129.32025 REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 25.42000 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 25.42000 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 43.10675 REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 86.21350 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: B, A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 SER A 2 REMARK 465 LYS A 3 REMARK 465 SER A 4 REMARK 465 GLU A 5 REMARK 465 SER A 6 REMARK 465 PRO A 7 REMARK 465 SER A 191 REMARK 465 SER A 192 REMARK 465 GLN A 193 REMARK 465 ARG A 194 REMARK 465 GLY A 195 REMARK 465 ARG A 196 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASN A 50 -79.27 -82.17 REMARK 500 THR A 51 -18.77 -49.45 REMARK 500 LYS A 52 12.23 58.42 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 2UP1 RELATED DB: PDB REMARK 900 STRUCTURE OF UP1-TELOMERIC DNA COMPLEX REMARK 900 RELATED ID: 1PGZ RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTAG(6-MI) REMARK 900 G); A HUMAN TELOMERIC REPEAT CONTAINING 6-METHYL-8-(2-DEOXY REMARK 900 --RIBOFURANOSYL)ISOXANTHOPTERIDINE (6-MI) REMARK 900 RELATED ID: 1PO6 RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGG(6MI)TTAGGG) REMARK 900 ; A HUMAN TELOMERIC REPEAT CONTAINING 6-METHYL-8-(2-DEOXY-- REMARK 900 RIBOFURANOSYL)ISOXANTHOPTERIDINE (6-MI) REMARK 900 RELATED ID: 1U1K RELATED DB: PDB REMARK 900 RELATED ID: 1U1L RELATED DB: PDB REMARK 900 RELATED ID: 1U1N RELATED DB: PDB REMARK 900 RELATED ID: 1U1O RELATED DB: PDB REMARK 900 RELATED ID: 1U1P RELATED DB: PDB REMARK 900 RELATED ID: 1U1Q RELATED DB: PDB REMARK 900 RELATED ID: 1U1R RELATED DB: PDB DBREF 1U1M A 1 196 UNP P09651 ROA1_HUMAN 0 195 DBREF 1U1M B 202 212 PDB 1U1M 1U1M 202 212 SEQRES 1 B 11 DT DA DG DG DG DT DT DA 7GU DG DG SEQRES 1 A 196 MET SER LYS SER GLU SER PRO LYS GLU PRO GLU GLN LEU SEQRES 2 A 196 ARG LYS LEU PHE ILE GLY GLY LEU SER PHE GLU THR THR SEQRES 3 A 196 ASP GLU SER LEU ARG SER HIS PHE GLU GLN TRP GLY THR SEQRES 4 A 196 LEU THR ASP CYS VAL VAL MET ARG ASP PRO ASN THR LYS SEQRES 5 A 196 ARG SER ARG GLY PHE GLY PHE VAL THR TYR ALA THR VAL SEQRES 6 A 196 GLU GLU VAL ASP ALA ALA MET ASN ALA ARG PRO HIS LYS SEQRES 7 A 196 VAL ASP GLY ARG VAL VAL GLU PRO LYS ARG ALA VAL SER SEQRES 8 A 196 ARG GLU ASP SER GLN ARG PRO GLY ALA HIS LEU THR VAL SEQRES 9 A 196 LYS LYS ILE PHE VAL GLY GLY ILE LYS GLU ASP THR GLU SEQRES 10 A 196 GLU HIS HIS LEU ARG ASP TYR PHE GLU GLN TYR GLY LYS SEQRES 11 A 196 ILE GLU VAL ILE GLU ILE MET THR ASP ARG GLY SER GLY SEQRES 12 A 196 LYS LYS ARG GLY PHE ALA PHE VAL THR PHE ASP ASP HIS SEQRES 13 A 196 ASP SER VAL ASP LYS ILE VAL ILE GLN LYS TYR HIS THR SEQRES 14 A 196 VAL ASN GLY HIS ASN CYS GLU VAL ARG LYS ALA LEU SER SEQRES 15 A 196 LYS GLN GLU MET ALA SER ALA SER SER SER GLN ARG GLY SEQRES 16 A 196 ARG MODRES 1U1M 7GU B 210 DG HET 7GU B 210 22 HETNAM 7GU 7-DEAZA-2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE FORMUL 1 7GU C11 H15 N4 O7 P FORMUL 3 HOH *114(H2 O) HELIX 1 1 PRO A 10 ARG A 14 1 5 HELIX 2 2 THR A 26 GLU A 35 1 10 HELIX 3 3 GLN A 36 GLY A 38 5 3 HELIX 4 4 THR A 64 ALA A 74 1 11 HELIX 5 5 GLU A 93 ARG A 97 5 5 HELIX 6 6 GLU A 117 GLU A 126 1 10 HELIX 7 7 GLN A 127 GLY A 129 5 3 HELIX 8 8 ASP A 155 ILE A 164 1 10 HELIX 9 9 SER A 182 SER A 190 1 9 SHEET 1 A 5 LEU A 40 ARG A 47 0 SHEET 2 A 5 SER A 54 TYR A 62 -1 O THR A 61 N THR A 41 SHEET 3 A 5 LYS A 15 GLY A 19 -1 N ILE A 18 O GLY A 58 SHEET 4 A 5 ARG A 82 ARG A 88 -1 O LYS A 87 N PHE A 17 SHEET 5 A 5 HIS A 77 VAL A 79 -1 N VAL A 79 O ARG A 82 SHEET 1 B 4 ILE A 131 THR A 138 0 SHEET 2 B 4 LYS A 145 PHE A 153 -1 O THR A 152 N GLU A 132 SHEET 3 B 4 LYS A 106 GLY A 110 -1 N VAL A 109 O ALA A 149 SHEET 4 B 4 GLU A 176 LYS A 179 -1 O GLU A 176 N GLY A 110 SHEET 1 C 2 THR A 169 VAL A 170 0 SHEET 2 C 2 HIS A 173 ASN A 174 -1 O HIS A 173 N VAL A 170 LINK O3' DA B 209 P 7GU B 210 1555 1555 1.60 LINK O3' 7GU B 210 P DG B 211 1555 1555 1.61 CISPEP 1 ARG A 75 PRO A 76 0 -0.02 CRYST1 50.840 50.840 172.427 90.00 90.00 90.00 P 43 21 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.019670 0.000000 0.000000 0.00000 SCALE2 0.000000 0.019670 0.000000 0.00000 SCALE3 0.000000 0.000000 0.005800 0.00000 ATOM 1 O5' DT B 202 0.855 36.756-180.253 1.00 34.37 O ATOM 2 C5' DT B 202 0.842 36.063-178.980 1.00 32.54 C ATOM 3 C4' DT B 202 1.410 34.661-178.863 1.00 31.92 C ATOM 4 O4' DT B 202 0.705 33.743-179.733 1.00 32.23 O ATOM 5 C3' DT B 202 2.893 34.503-179.203 1.00 33.02 C ATOM 6 O3' DT B 202 3.520 33.549-178.337 1.00 33.89 O ATOM 7 C2' DT B 202 2.874 33.963-180.620 1.00 31.96 C ATOM 8 C1' DT B 202 1.608 33.126-180.645 1.00 32.48 C ATOM 9 N1 DT B 202 0.962 33.097-181.974 1.00 36.02 N ATOM 10 C2 DT B 202 0.965 31.915-182.688 1.00 37.28 C ATOM 11 O2 DT B 202 1.480 30.881-182.284 1.00 37.93 O ATOM 12 N3 DT B 202 0.335 31.987-183.907 1.00 37.36 N ATOM 13 C4 DT B 202 -0.285 33.089-184.470 1.00 39.60 C ATOM 14 O4 DT B 202 -0.817 32.993-185.577 1.00 41.13 O ATOM 15 C5 DT B 202 -0.249 34.295-183.664 1.00 38.93 C ATOM 16 C7 DT B 202 -0.898 35.544-184.181 1.00 39.09 C ATOM 17 C6 DT B 202 0.367 34.237-182.478 1.00 37.67 C ATOM 18 P DA B 203 5.106 33.629-178.075 1.00 34.30 P ATOM 19 OP1 DA B 203 5.433 35.034-177.738 1.00 32.83 O ATOM 20 OP2 DA B 203 5.816 32.957-179.189 1.00 34.25 O ATOM 21 O5' DA B 203 5.309 32.746-176.765 1.00 34.10 O ATOM 22 C5' DA B 203 4.634 33.070-175.545 1.00 33.17 C ATOM 23 C4' DA B 203 5.066 32.127-174.446 1.00 31.10 C ATOM 24 O4' DA B 203 4.644 30.787-174.773 1.00 30.30 O ATOM 25 C3' DA B 203 6.578 32.041-174.241 1.00 32.19 C ATOM 26 O3' DA B 203 6.855 31.652-172.900 1.00 31.32 O ATOM 27 C2' DA B 203 6.964 30.876-175.132 1.00 30.60 C ATOM 28 C1' DA B 203 5.782 29.948-174.915 1.00 29.39 C ATOM 29 N9 DA B 203 5.514 29.016-176.009 1.00 25.42 N ATOM 30 C8 DA B 203 5.475 29.267-177.357 1.00 24.94 C ATOM 31 N7 DA B 203 5.202 28.213-178.081 1.00 23.77 N ATOM 32 C5 DA B 203 5.050 27.198-177.147 1.00 24.11 C ATOM 33 C6 DA B 203 4.758 25.833-177.279 1.00 24.58 C ATOM 34 N6 DA B 203 4.549 25.234-178.457 1.00 24.93 N ATOM 35 N1 DA B 203 4.686 25.094-176.148 1.00 24.46 N ATOM 36 C2 DA B 203 4.899 25.701-174.972 1.00 24.76 C ATOM 37 N3 DA B 203 5.179 26.976-174.721 1.00 23.67 N ATOM 38 C4 DA B 203 5.241 27.679-175.866 1.00 22.96 C ATOM 39 P DG B 204 6.686 32.702-171.702 1.00 29.13 P ATOM 40 OP1 DG B 204 6.811 34.079-172.233 1.00 26.15 O ATOM 41 OP2 DG B 204 7.618 32.236-170.638 1.00 28.45 O ATOM 42 O5' DG B 204 5.188 32.484-171.199 1.00 26.86 O ATOM 43 C5' DG B 204 4.605 31.179-171.179 1.00 24.83 C ATOM 44 C4' DG B 204 3.653 31.039-170.012 1.00 24.03 C ATOM 45 O4' DG B 204 2.941 29.782-170.105 1.00 24.66 O ATOM 46 C3' DG B 204 4.313 31.026-168.635 1.00 25.81 C ATOM 47 O3' DG B 204 3.365 31.538-167.693 1.00 28.78 O ATOM 48 C2' DG B 204 4.520 29.543-168.379 1.00 26.79 C ATOM 49 C1' DG B 204 3.248 28.970-168.974 1.00 24.21 C ATOM 50 N9 DG B 204 3.285 27.574-169.410 1.00 23.15 N ATOM 51 C8 DG B 204 2.329 26.627-169.137 1.00 21.35 C ATOM 52 N7 DG B 204 2.585 25.467-169.673 1.00 22.45 N ATOM 53 C5 DG B 204 3.793 25.649-170.331 1.00 21.18 C ATOM 54 C6 DG B 204 4.570 24.736-171.082 1.00 22.73 C ATOM 55 O6 DG B 204 4.355 23.545-171.303 1.00 21.97 O ATOM 56 N1 DG B 204 5.709 25.329-171.590 1.00 22.27 N ATOM 57 C2 DG B 204 6.078 26.624-171.392 1.00 22.11 C ATOM 58 N2 DG B 204 7.238 26.980-171.981 1.00 21.00 N ATOM 59 N3 DG B 204 5.373 27.498-170.678 1.00 22.71 N ATOM 60 C4 DG B 204 4.246 26.943-170.180 1.00 22.33 C ATOM 61 P DG B 205 3.851 32.457-166.475 1.00 38.07 P ATOM 62 OP1 DG B 205 3.853 33.860-166.953 1.00 33.66 O ATOM 63 OP2 DG B 205 5.089 31.873-165.910 1.00 33.15 O ATOM 64 O5' DG B 205 2.687 32.274-165.406 1.00 37.58 O ATOM 65 C5' DG B 205 1.494 33.059-165.471 1.00 36.59 C ATOM 66 C4' DG B 205 0.457 32.522-164.508 1.00 36.03 C ATOM 67 O4' DG B 205 -0.136 31.309-165.030 1.00 35.17 O ATOM 68 C3' DG B 205 0.975 32.174-163.110 1.00 35.04 C ATOM 69 O3' DG B 205 -0.024 32.487-162.126 1.00 34.83 O ATOM 70 C2' DG B 205 1.174 30.669-163.187 1.00 34.83 C ATOM 71 C1' DG B 205 0.038 30.241-164.108 1.00 33.02 C ATOM 72 N9 DG B 205 0.269 29.023-164.885 1.00 28.89 N ATOM 73 C8 DG B 205 1.461 28.583-165.417 1.00 26.75 C ATOM 74 N7 DG B 205 1.339 27.477-166.096 1.00 27.42 N ATOM 75 C5 DG B 205 -0.010 27.160-166.003 1.00 26.66 C ATOM 76 C6 DG B 205 -0.739 26.065-166.542 1.00 26.92 C ATOM 77 O6 DG B 205 -0.326 25.130-167.237 1.00 24.31 O ATOM 78 N1 DG B 205 -2.085 26.125-166.195 1.00 27.00 N ATOM 79 C2 DG B 205 -2.661 27.114-165.435 1.00 28.17 C ATOM 80 N2 DG B 205 -3.978 27.002-165.223 1.00 26.27 N ATOM 81 N3 DG B 205 -1.995 28.136-164.927 1.00 27.47 N ATOM 82 C4 DG B 205 -0.682 28.097-165.249 1.00 28.54 C ATOM 83 P DG B 206 0.059 33.873-161.310 1.00 41.64 P ATOM 84 OP1 DG B 206 -1.111 33.939-160.397 1.00129.14 O ATOM 85 OP2 DG B 206 0.285 34.961-162.295 1.00127.15 O ATOM 86 O5' DG B 206 1.375 33.729-160.430 1.00 41.59 O ATOM 87 C5' DG B 206 1.457 32.743-159.412 1.00 44.84 C ATOM 88 C4' DG B 206 2.898 32.513-159.029 1.00 48.50 C ATOM 89 O4' DG B 206 3.452 33.724-158.464 1.00 51.68 O ATOM 90 C3' DG B 206 3.077 31.427-157.972 1.00 48.19 C ATOM 91 O3' DG B 206 4.196 30.615-158.298 1.00 45.81 O ATOM 92 C2' DG B 206 3.305 32.190-156.684 1.00 50.03 C ATOM 93 C1' DG B 206 3.950 33.479-157.154 1.00 53.17 C ATOM 94 N9 DG B 206 3.601 34.620-156.312 1.00142.49 N ATOM 95 C8 DG B 206 2.370 35.227-156.199 1.00142.79 C ATOM 96 N7 DG B 206 2.365 36.220-155.352 1.00144.22 N ATOM 97 C5 DG B 206 3.670 36.276-154.878 1.00144.61 C ATOM 98 C6 DG B 206 4.272 37.155-153.935 1.00145.31 C ATOM 99 O6 DG B 206 3.754 38.091-153.310 1.00146.07 O ATOM 100 N1 DG B 206 5.619 36.857-153.746 1.00145.67 N ATOM 101 C2 DG B 206 6.302 35.848-154.379 1.00145.51 C ATOM 102 N2 DG B 206 7.599 35.721-154.060 1.00144.96 N ATOM 103 N3 DG B 206 5.755 35.025-155.260 1.00145.68 N ATOM 104 C4 DG B 206 4.446 35.295-155.461 1.00143.98 C ATOM 105 P DT B 207 3.940 29.151-158.886 1.00 32.31 P ATOM 106 OP1 DT B 207 2.977 29.281-159.999 1.00 31.34 O ATOM 107 OP2 DT B 207 3.615 28.275-157.736 1.00 30.46 O ATOM 108 O5' DT B 207 5.349 28.727-159.485 1.00 32.17 O ATOM 109 C5' DT B 207 6.367 28.169-158.653 1.00 28.62 C ATOM 110 C4' DT B 207 7.372 27.429-159.503 1.00 27.96 C ATOM 111 O4' DT B 207 6.675 26.395-160.229 1.00 29.51 O ATOM 112 C3' DT B 207 8.063 28.284-160.566 1.00 28.92 C ATOM 113 O3' DT B 207 9.368 27.753-160.793 1.00 27.96 O ATOM 114 C2' DT B 207 7.211 28.051-161.799 1.00 26.28 C ATOM 115 C1' DT B 207 6.854 26.588-161.626 1.00 26.61 C ATOM 116 N1 DT B 207 5.635 26.120-162.308 1.00 25.93 N ATOM 117 C2 DT B 207 5.772 25.180-163.311 1.00 24.85 C ATOM 118 O2 DT B 207 6.854 24.784-163.718 1.00 26.23 O ATOM 119 N3 DT B 207 4.589 24.720-163.825 1.00 26.37 N ATOM 120 C4 DT B 207 3.317 25.107-163.460 1.00 24.61 C ATOM 121 O4 DT B 207 2.347 24.576-163.986 1.00 19.06 O ATOM 122 C5 DT B 207 3.248 26.137-162.442 1.00 25.24 C ATOM 123 C7 DT B 207 1.910 26.652-162.011 1.00 24.23 C ATOM 124 C6 DT B 207 4.396 26.584-161.927 1.00 24.26 C ATOM 125 P DT B 208 10.630 28.733-160.917 1.00 30.87 P ATOM 126 OP1 DT B 208 10.543 29.757-159.845 1.00 35.25 O ATOM 127 OP2 DT B 208 10.771 29.159-162.330 1.00 36.22 O ATOM 128 O5' DT B 208 11.847 27.768-160.580 1.00 29.12 O ATOM 129 C5' DT B 208 12.009 27.219-159.272 1.00 28.50 C ATOM 130 C4' DT B 208 13.257 26.370-159.224 1.00 27.88 C ATOM 131 O4' DT B 208 13.054 25.195-160.045 1.00 29.27 O ATOM 132 C3' DT B 208 14.502 27.057-159.778 1.00 27.79 C ATOM 133 O3' DT B 208 15.648 26.594-159.075 1.00 30.19 O ATOM 134 C2' DT B 208 14.553 26.580-161.216 1.00 28.32 C ATOM 135 C1' DT B 208 13.979 25.175-161.120 1.00 29.13 C ATOM 136 N1 DT B 208 13.264 24.733-162.340 1.00 33.34 N ATOM 137 C2 DT B 208 13.798 23.675-163.046 1.00 33.03 C ATOM 138 O2 DT B 208 14.792 23.057-162.682 1.00 35.15 O ATOM 139 N3 DT B 208 13.121 23.361-164.203 1.00 33.17 N ATOM 140 C4 DT B 208 11.985 23.973-164.701 1.00 31.86 C ATOM 141 O4 DT B 208 11.499 23.588-165.767 1.00 29.39 O ATOM 142 C5 DT B 208 11.460 25.051-163.892 1.00 32.80 C ATOM 143 C7 DT B 208 10.214 25.753-164.339 1.00 31.04 C ATOM 144 C6 DT B 208 12.117 25.373-162.768 1.00 32.91 C ATOM 145 P DA B 209 17.040 27.385-159.198 1.00 35.13 P ATOM 146 OP1 DA B 209 16.811 28.787-158.766 1.00 31.91 O ATOM 147 OP2 DA B 209 17.613 27.107-160.542 1.00 31.55 O ATOM 148 O5' DA B 209 17.969 26.664-158.122 1.00 34.60 O ATOM 149 C5' DA B 209 17.608 26.624-156.740 1.00 32.97 C ATOM 150 C4' DA B 209 18.715 25.980-155.937 1.00 32.99 C ATOM 151 O4' DA B 209 18.819 24.573-156.275 1.00 32.73 O ATOM 152 C3' DA B 209 20.103 26.569-156.199 1.00 33.14 C ATOM 153 O3' DA B 209 20.910 26.474-155.027 1.00 34.64 O ATOM 154 C2' DA B 209 20.685 25.615-157.221 1.00 34.60 C ATOM 155 C1' DA B 209 20.146 24.300-156.696 1.00 33.38 C ATOM 156 N9 DA B 209 20.115 23.207-157.662 1.00 31.51 N ATOM 157 C8 DA B 209 19.773 23.244-158.991 1.00 30.14 C ATOM 158 N7 DA B 209 19.884 22.088-159.598 1.00 29.26 N ATOM 159 C5 DA B 209 20.317 21.230-158.601 1.00 28.01 C ATOM 160 C6 DA B 209 20.618 19.863-158.602 1.00 27.65 C ATOM 161 N6 DA B 209 20.513 19.091-159.682 1.00 27.41 N ATOM 162 N1 DA B 209 21.030 19.307-157.439 1.00 25.38 N ATOM 163 C2 DA B 209 21.118 20.085-156.354 1.00 24.38 C ATOM 164 N3 DA B 209 20.856 21.383-156.226 1.00 29.49 N ATOM 165 C4 DA B 209 20.458 21.904-157.401 1.00 29.36 C HETATM 166 P 7GU B 210 20.696 27.499-153.812 1.00 36.23 P HETATM 167 OP1 7GU B 210 20.215 28.806-154.328 1.00 27.36 O HETATM 168 OP2 7GU B 210 21.963 27.427-153.061 1.00 31.91 O HETATM 169 O5' 7GU B 210 19.570 26.827-152.909 1.00 35.37 O HETATM 170 N9 7GU B 210 20.047 21.798-150.153 1.00 35.32 N HETATM 171 C4 7GU B 210 20.868 21.242-151.080 1.00 38.76 C HETATM 172 N3 7GU B 210 21.561 21.927-152.041 1.00 42.50 N HETATM 173 C2 7GU B 210 22.282 21.127-152.822 1.00 45.21 C HETATM 174 N2 7GU B 210 23.025 21.645-153.815 1.00 44.40 N HETATM 175 N1 7GU B 210 22.309 19.742-152.667 1.00 44.97 N HETATM 176 C6 7GU B 210 21.597 19.020-151.680 1.00 43.28 C HETATM 177 O6 7GU B 210 21.692 17.788-151.638 1.00 44.94 O HETATM 178 C5 7GU B 210 20.823 19.880-150.831 1.00 39.48 C HETATM 179 C7 7GU B 210 19.988 19.604-149.751 1.00 38.26 C HETATM 180 C8 7GU B 210 19.548 20.776-149.381 1.00 35.62 C HETATM 181 C2' 7GU B 210 20.743 24.297-149.636 1.00 39.46 C HETATM 182 C5' 7GU B 210 19.506 25.407-152.756 1.00 36.50 C HETATM 183 C4' 7GU B 210 19.230 25.031-151.315 1.00 36.73 C HETATM 184 O4' 7GU B 210 18.886 23.657-151.074 1.00 37.64 O HETATM 185 C1' 7GU B 210 19.747 23.217-150.039 1.00 40.04 C HETATM 186 C3' 7GU B 210 19.962 25.530-150.070 1.00 38.60 C HETATM 187 O3' 7GU B 210 19.095 26.127-149.114 1.00 38.78 O ATOM 188 P DG B 211 19.683 26.732-147.747 1.00 46.00 P ATOM 189 OP1 DG B 211 18.514 27.336-147.061 1.00 42.47 O ATOM 190 OP2 DG B 211 20.859 27.575-148.080 1.00 46.03 O ATOM 191 O5' DG B 211 20.169 25.463-146.913 1.00 46.38 O ATOM 192 C5' DG B 211 19.220 24.583-146.315 1.00 46.85 C ATOM 193 C4' DG B 211 19.910 23.414-145.650 1.00 49.14 C ATOM 194 O4' DG B 211 20.558 22.573-146.636 1.00 51.13 O ATOM 195 C3' DG B 211 20.984 23.739-144.604 1.00 51.09 C ATOM 196 O3' DG B 211 20.875 22.775-143.543 1.00 53.38 O ATOM 197 C2' DG B 211 22.274 23.491-145.363 1.00 50.29 C ATOM 198 C1' DG B 211 21.866 22.282-146.178 1.00 49.47 C ATOM 199 N9 DG B 211 22.702 21.962-147.328 1.00 47.29 N ATOM 200 C8 DG B 211 23.419 22.830-148.116 1.00 46.87 C ATOM 201 N7 DG B 211 24.091 22.228-149.057 1.00 46.39 N ATOM 202 C5 DG B 211 23.795 20.882-148.884 1.00 46.38 C ATOM 203 C6 DG B 211 24.235 19.746-149.605 1.00 45.64 C ATOM 204 O6 DG B 211 25.000 19.702-150.576 1.00 45.35 O ATOM 205 N1 DG B 211 23.692 18.570-149.089 1.00 45.46 N ATOM 206 C2 DG B 211 22.834 18.498-148.018 1.00 46.41 C ATOM 207 N2 DG B 211 22.419 17.271-147.666 1.00 46.99 N ATOM 208 N3 DG B 211 22.413 19.553-147.341 1.00 45.86 N ATOM 209 C4 DG B 211 22.933 20.704-147.824 1.00 46.93 C ATOM 210 P DG B 212 21.813 22.885-142.236 1.00 91.73 P ATOM 211 OP1 DG B 212 21.085 23.731-141.254 1.00 62.48 O ATOM 212 OP2 DG B 212 23.195 23.257-142.639 1.00 61.87 O ATOM 213 O5' DG B 212 21.828 21.388-141.684 1.00 92.58 O ATOM 214 C5' DG B 212 23.041 20.635-141.570 1.00 90.24 C ATOM 215 C4' DG B 212 23.000 19.439-142.496 1.00 89.31 C ATOM 216 O4' DG B 212 23.309 19.879-143.844 1.00 87.09 O ATOM 217 C3' DG B 212 24.019 18.345-142.180 1.00 88.33 C ATOM 218 O3' DG B 212 23.518 17.092-142.653 1.00 90.17 O ATOM 219 C2' DG B 212 25.196 18.704-143.065 1.00 87.02 C ATOM 220 C1' DG B 212 24.509 19.262-144.302 1.00 85.73 C ATOM 221 N9 DG B 212 25.307 20.268-145.001 1.00 52.56 N ATOM 222 C8 DG B 212 25.507 21.576-144.629 1.00 51.84 C ATOM 223 N7 DG B 212 26.316 22.221-145.429 1.00 52.07 N ATOM 224 C5 DG B 212 26.668 21.287-146.394 1.00 51.45 C ATOM 225 C6 DG B 212 27.542 21.403-147.520 1.00 50.57 C ATOM 226 O6 DG B 212 28.211 22.386-147.887 1.00 50.72 O ATOM 227 N1 DG B 212 27.600 20.212-148.244 1.00 49.75 N ATOM 228 C2 DG B 212 26.916 19.057-147.926 1.00 49.75 C ATOM 229 N2 DG B 212 27.088 18.016-148.757 1.00 46.46 N ATOM 230 N3 DG B 212 26.116 18.934-146.874 1.00 50.29 N ATOM 231 C4 DG B 212 26.039 20.079-146.157 1.00 51.65 C TER 232 DG B 212 ATOM 233 N LYS A 8 -2.026 7.108-165.755 1.00 67.23 N ATOM 234 CA LYS A 8 -2.386 8.247-166.643 1.00 66.14 C ATOM 235 C LYS A 8 -1.133 8.725-167.364 1.00 65.30 C ATOM 236 O LYS A 8 -0.013 8.437-166.941 1.00 67.08 O ATOM 237 CB LYS A 8 -2.973 9.391-165.815 1.00 36.78 C ATOM 238 CG LYS A 8 -3.840 10.353-166.611 1.00 40.41 C ATOM 239 CD LYS A 8 -4.278 11.554-165.781 1.00 38.42 C ATOM 240 CE LYS A 8 -5.275 11.174-164.699 1.00 40.18 C ATOM 241 NZ LYS A 8 -4.748 10.140-163.763 1.00 38.60 N ATOM 242 N GLU A 9 -1.324 9.456-168.456 1.00 36.15 N ATOM 243 CA GLU A 9 -0.202 9.973-169.238 1.00 34.05 C ATOM 244 C GLU A 9 0.305 11.261-168.615 1.00 31.71 C ATOM 245 O GLU A 9 -0.438 11.948-167.920 1.00 31.83 O ATOM 246 CB GLU A 9 -0.654 10.215-170.674 1.00 37.87 C ATOM 247 CG GLU A 9 -1.000 8.939-171.405 1.00 39.07 C ATOM 248 CD GLU A 9 -2.184 9.092-172.338 1.00 37.85 C ATOM 249 OE1 GLU A 9 -2.179 8.450-173.409 1.00 38.62 O ATOM 250 OE2 GLU A 9 -3.129 9.841-172.002 1.00 36.29 O ATOM 251 N PRO A 10 1.581 11.608-168.857 1.00 26.55 N ATOM 252 CA PRO A 10 2.172 12.833-168.299 1.00 26.19 C ATOM 253 C PRO A 10 1.436 14.086-168.741 1.00 23.95 C ATOM 254 O PRO A 10 1.045 14.210-169.904 1.00 22.08 O ATOM 255 CB PRO A 10 3.606 12.817-168.830 1.00 26.00 C ATOM 256 CG PRO A 10 3.881 11.371-169.078 1.00 26.74 C ATOM 257 CD PRO A 10 2.571 10.877-169.666 1.00 24.57 C ATOM 258 N GLU A 11 1.272 15.009-167.800 1.00 23.39 N ATOM 259 CA GLU A 11 0.606 16.273-168.041 1.00 22.38 C ATOM 260 C GLU A 11 1.191 16.979-169.264 1.00 21.83 C ATOM 261 O GLU A 11 0.453 17.461-170.118 1.00 21.93 O ATOM 262 CB GLU A 11 0.742 17.168-166.801 1.00 21.82 C ATOM 263 CG GLU A 11 0.004 18.501-166.874 1.00 21.25 C ATOM 264 CD GLU A 11 0.905 19.680-167.208 1.00 21.26 C ATOM 265 OE1 GLU A 11 2.147 19.523-167.154 1.00 18.19 O ATOM 266 OE2 GLU A 11 0.370 20.773-167.510 1.00 23.52 O ATOM 267 N GLN A 12 2.514 17.027-169.359 1.00 23.42 N ATOM 268 CA GLN A 12 3.151 17.702-170.484 1.00 22.99 C ATOM 269 C GLN A 12 2.704 17.164-171.840 1.00 23.09 C ATOM 270 O GLN A 12 2.565 17.930-172.798 1.00 23.27 O ATOM 271 CB GLN A 12 4.671 17.601-170.396 1.00 25.78 C ATOM 272 CG GLN A 12 5.382 18.510-171.402 1.00 22.73 C ATOM 273 CD GLN A 12 5.254 19.981-171.039 1.00 24.35 C ATOM 274 OE1 GLN A 12 4.985 20.828-171.891 1.00 27.20 O ATOM 275 NE2 GLN A 12 5.448 20.289-169.763 1.00 20.77 N ATOM 276 N LEU A 13 2.474 15.856-171.923 1.00 22.79 N ATOM 277 CA LEU A 13 2.054 15.228-173.174 1.00 24.64 C ATOM 278 C LEU A 13 0.550 15.301-173.396 1.00 25.56 C ATOM 279 O LEU A 13 0.053 14.888-174.448 1.00 22.93 O ATOM 280 CB LEU A 13 2.497 13.759-173.206 1.00 21.67 C ATOM 281 CG LEU A 13 3.999 13.465-173.291 1.00 25.41 C ATOM 282 CD1 LEU A 13 4.231 11.970-173.177 1.00 26.59 C ATOM 283 CD2 LEU A 13 4.561 14.001-174.614 1.00 26.41 C ATOM 284 N ARG A 14 -0.178 15.813-172.407 1.00 28.37 N ATOM 285 CA ARG A 14 -1.629 15.934-172.531 1.00 28.33 C ATOM 286 C ARG A 14 -2.034 17.382-172.787 1.00 28.84 C ATOM 287 O ARG A 14 -3.212 17.683-172.951 1.00 28.95 O ATOM 288 CB ARG A 14 -2.322 15.416-171.261 1.00 26.40 C ATOM 289 CG ARG A 14 -2.181 13.906-171.064 1.00 25.62 C ATOM 290 CD ARG A 14 -2.967 13.389-169.855 1.00 25.30 C ATOM 291 NE ARG A 14 -2.431 13.864-168.580 1.00 26.05 N ATOM 292 CZ ARG A 14 -2.937 14.871-167.873 1.00 27.90 C ATOM 293 NH1 ARG A 14 -4.009 15.533-168.300 1.00 26.29 N ATOM 294 NH2 ARG A 14 -2.368 15.213-166.727 1.00 26.00 N ATOM 295 N LYS A 15 -1.046 18.270-172.853 1.00 24.89 N ATOM 296 CA LYS A 15 -1.302 19.695-173.055 1.00 25.09 C ATOM 297 C LYS A 15 -0.877 20.284-174.407 1.00 25.48 C ATOM 298 O LYS A 15 0.160 19.926-174.967 1.00 24.57 O ATOM 299 CB LYS A 15 -0.633 20.478-171.918 1.00 28.86 C ATOM 300 CG LYS A 15 -0.579 21.982-172.112 1.00 27.31 C ATOM 301 CD LYS A 15 -0.106 22.691-170.833 1.00 26.34 C ATOM 302 CE LYS A 15 1.208 22.126-170.304 1.00 26.53 C ATOM 303 NZ LYS A 15 1.756 22.940-169.177 1.00 20.94 N ATOM 304 N LEU A 16 -1.699 21.202-174.908 1.00 21.90 N ATOM 305 CA LEU A 16 -1.456 21.908-176.164 1.00 24.87 C ATOM 306 C LEU A 16 -1.331 23.405-175.917 1.00 25.31 C ATOM 307 O LEU A 16 -2.045 23.979-175.095 1.00 25.06 O ATOM 308 CB LEU A 16 -2.616 21.711-177.145 1.00 17.04 C ATOM 309 CG LEU A 16 -2.877 20.379-177.853 1.00 16.70 C ATOM 310 CD1 LEU A 16 -4.141 20.515-178.702 1.00 18.33 C ATOM 311 CD2 LEU A 16 -1.686 19.987-178.713 1.00 17.58 C ATOM 312 N PHE A 17 -0.408 24.026-176.631 1.00 18.06 N ATOM 313 CA PHE A 17 -0.210 25.465-176.577 1.00 19.32 C ATOM 314 C PHE A 17 -1.184 25.989-177.638 1.00 18.98 C ATOM 315 O PHE A 17 -1.340 25.373-178.695 1.00 21.75 O ATOM 316 CB PHE A 17 1.234 25.806-176.983 1.00 23.65 C ATOM 317 CG PHE A 17 1.430 27.235-177.407 1.00 23.12 C ATOM 318 CD1 PHE A 17 1.772 28.214-176.476 1.00 24.18 C ATOM 319 CD2 PHE A 17 1.248 27.603-178.736 1.00 26.06 C ATOM 320 CE1 PHE A 17 1.931 29.552-176.865 1.00 24.63 C ATOM 321 CE2 PHE A 17 1.399 28.929-179.139 1.00 25.46 C ATOM 322 CZ PHE A 17 1.743 29.912-178.195 1.00 27.52 C ATOM 323 N ILE A 18 -1.863 27.098-177.359 1.00 21.20 N ATOM 324 CA ILE A 18 -2.791 27.665-178.333 1.00 21.40 C ATOM 325 C ILE A 18 -2.383 29.106-178.604 1.00 19.76 C ATOM 326 O ILE A 18 -2.638 29.996-177.786 1.00 21.68 O ATOM 327 CB ILE A 18 -4.253 27.656-177.819 1.00 16.47 C ATOM 328 CG1 ILE A 18 -4.634 26.264-177.296 1.00 19.19 C ATOM 329 CG2 ILE A 18 -5.204 28.084-178.961 1.00 19.73 C ATOM 330 CD1 ILE A 18 -4.744 25.177-178.359 1.00 17.31 C ATOM 331 N GLY A 19 -1.753 29.338-179.753 1.00 22.70 N ATOM 332 CA GLY A 19 -1.316 30.684-180.090 1.00 23.68 C ATOM 333 C GLY A 19 -2.285 31.469-180.953 1.00 25.06 C ATOM 334 O GLY A 19 -3.199 30.900-181.542 1.00 24.96 O ATOM 335 N GLY A 20 -2.084 32.786-181.016 1.00 22.95 N ATOM 336 CA GLY A 20 -2.939 33.651-181.818 1.00 23.62 C ATOM 337 C GLY A 20 -4.383 33.730-181.359 1.00 23.85 C ATOM 338 O GLY A 20 -5.308 33.882-182.171 1.00 23.68 O ATOM 339 N LEU A 21 -4.593 33.608-180.053 1.00 23.25 N ATOM 340 CA LEU A 21 -5.938 33.692-179.519 1.00 24.71 C ATOM 341 C LEU A 21 -6.449 35.117-179.698 1.00 25.05 C ATOM 342 O LEU A 21 -5.683 36.079-179.575 1.00 26.34 O ATOM 343 CB LEU A 21 -5.956 33.361-178.022 1.00 29.04 C ATOM 344 CG LEU A 21 -5.865 31.920-177.525 1.00 30.18 C ATOM 345 CD1 LEU A 21 -6.075 31.930-176.025 1.00 33.58 C ATOM 346 CD2 LEU A 21 -6.923 31.048-178.195 1.00 31.03 C ATOM 347 N SER A 22 -7.743 35.245-179.981 1.00 32.71 N ATOM 348 CA SER A 22 -8.361 36.557-180.132 1.00 36.12 C ATOM 349 C SER A 22 -8.335 37.281-178.790 1.00 36.54 C ATOM 350 O SER A 22 -8.246 36.653-177.730 1.00 35.70 O ATOM 351 CB SER A 22 -9.811 36.420-180.570 1.00 34.81 C ATOM 352 OG SER A 22 -10.538 37.560-180.154 1.00 36.20 O ATOM 353 N PHE A 23 -8.433 38.602-178.840 1.00 38.02 N ATOM 354 CA PHE A 23 -8.425 39.413-177.628 1.00 40.11 C ATOM 355 C PHE A 23 -9.629 39.109-176.734 1.00 39.22 C ATOM 356 O PHE A 23 -9.574 39.313-175.522 1.00 38.23 O ATOM 357 CB PHE A 23 -8.405 40.899-178.003 1.00 88.00 C ATOM 358 CG PHE A 23 -9.571 41.334-178.854 1.00 92.85 C ATOM 359 CD1 PHE A 23 -10.789 41.674-178.272 1.00 94.20 C ATOM 360 CD2 PHE A 23 -9.448 41.410-180.237 1.00 94.63 C ATOM 361 CE1 PHE A 23 -11.864 42.086-179.055 1.00 95.84 C ATOM 362 CE2 PHE A 23 -10.519 41.821-181.028 1.00 95.79 C ATOM 363 CZ PHE A 23 -11.728 42.159-180.434 1.00 95.20 C ATOM 364 N GLU A 24 -10.709 38.619-177.341 1.00 37.28 N ATOM 365 CA GLU A 24 -11.938 38.292-176.617 1.00 38.38 C ATOM 366 C GLU A 24 -11.921 36.949-175.907 1.00 37.19 C ATOM 367 O GLU A 24 -12.648 36.750-174.934 1.00 35.77 O ATOM 368 CB GLU A 24 -13.136 38.275-177.561 1.00 57.23 C ATOM 369 CG GLU A 24 -13.668 39.619-177.950 1.00 62.16 C ATOM 370 CD GLU A 24 -15.150 39.562-178.231 1.00 65.61 C ATOM 371 OE1 GLU A 24 -15.932 39.393-177.266 1.00 65.82 O ATOM 372 OE2 GLU A 24 -15.532 39.671-179.414 1.00 68.96 O ATOM 373 N THR A 25 -11.116 36.020-176.405 1.00 33.57 N ATOM 374 CA THR A 25 -11.069 34.693-175.819 1.00 31.33 C ATOM 375 C THR A 25 -10.711 34.673-174.341 1.00 29.60 C ATOM 376 O THR A 25 -9.769 35.332-173.903 1.00 29.67 O ATOM 377 CB THR A 25 -10.107 33.792-176.597 1.00 23.48 C ATOM 378 OG1 THR A 25 -10.487 33.801-177.979 1.00 22.92 O ATOM 379 CG2 THR A 25 -10.175 32.358-176.066 1.00 21.16 C ATOM 380 N THR A 26 -11.486 33.905-173.581 1.00 22.83 N ATOM 381 CA THR A 26 -11.282 33.769-172.143 1.00 24.18 C ATOM 382 C THR A 26 -11.171 32.301-171.803 1.00 23.65 C ATOM 383 O THR A 26 -11.430 31.446-172.651 1.00 23.65 O ATOM 384 CB THR A 26 -12.466 34.343-171.361 1.00 34.68 C ATOM 385 OG1 THR A 26 -13.671 33.704-171.800 1.00 40.86 O ATOM 386 CG2 THR A 26 -12.576 35.843-171.590 1.00 33.27 C ATOM 387 N ASP A 27 -10.783 32.005-170.568 1.00 32.94 N ATOM 388 CA ASP A 27 -10.662 30.616-170.140 1.00 34.35 C ATOM 389 C ASP A 27 -11.924 29.887-170.552 1.00 33.43 C ATOM 390 O ASP A 27 -11.880 28.751-171.026 1.00 30.66 O ATOM 391 CB ASP A 27 -10.527 30.525-168.622 1.00 33.76 C ATOM 392 CG ASP A 27 -9.240 31.119-168.113 1.00 33.89 C ATOM 393 OD1 ASP A 27 -8.509 31.759-168.904 1.00 33.39 O ATOM 394 OD2 ASP A 27 -8.963 30.949-166.910 1.00 35.86 O ATOM 395 N GLU A 28 -13.049 30.568-170.368 1.00 35.01 N ATOM 396 CA GLU A 28 -14.364 30.026-170.675 1.00 36.38 C ATOM 397 C GLU A 28 -14.604 29.742-172.150 1.00 35.21 C ATOM 398 O GLU A 28 -15.018 28.638-172.496 1.00 35.59 O ATOM 399 CB GLU A 28 -15.448 30.975-170.161 1.00 86.18 C ATOM 400 CG GLU A 28 -15.327 31.302-168.686 1.00 93.52 C ATOM 401 CD GLU A 28 -15.436 30.074-167.801 1.00 98.18 C ATOM 402 OE1 GLU A 28 -15.285 30.218-166.569 1.00101.45 O ATOM 403 OE2 GLU A 28 -15.677 28.968-168.331 1.00100.99 O ATOM 404 N SER A 29 -14.360 30.726-173.018 1.00 31.37 N ATOM 405 CA SER A 29 -14.583 30.528-174.453 1.00 30.24 C ATOM 406 C SER A 29 -13.606 29.513-175.044 1.00 30.66 C ATOM 407 O SER A 29 -13.939 28.804-175.997 1.00 32.08 O ATOM 408 CB SER A 29 -14.510 31.869-175.221 1.00 24.51 C ATOM 409 OG SER A 29 -13.262 32.521-175.056 1.00 25.24 O ATOM 410 N LEU A 30 -12.408 29.436-174.470 1.00 28.09 N ATOM 411 CA LEU A 30 -11.405 28.483-174.943 1.00 28.23 C ATOM 412 C LEU A 30 -11.908 27.088-174.583 1.00 29.14 C ATOM 413 O LEU A 30 -12.047 26.215-175.447 1.00 28.54 O ATOM 414 CB LEU A 30 -10.059 28.744-174.260 1.00 23.97 C ATOM 415 CG LEU A 30 -8.827 28.042-174.846 1.00 24.39 C ATOM 416 CD1 LEU A 30 -8.603 28.466-176.304 1.00 20.98 C ATOM 417 CD2 LEU A 30 -7.623 28.389-173.998 1.00 22.04 C ATOM 418 N ARG A 31 -12.193 26.889-173.300 1.00 32.60 N ATOM 419 CA ARG A 31 -12.701 25.609-172.817 1.00 33.03 C ATOM 420 C ARG A 31 -13.895 25.149-173.652 1.00 34.31 C ATOM 421 O ARG A 31 -13.921 24.027-174.155 1.00 34.51 O ATOM 422 CB ARG A 31 -13.111 25.726-171.341 1.00 32.74 C ATOM 423 CG ARG A 31 -13.900 24.529-170.807 1.00 34.89 C ATOM 424 CD ARG A 31 -14.171 24.642-169.300 1.00 35.48 C ATOM 425 NE ARG A 31 -12.986 24.367-168.480 1.00 37.35 N ATOM 426 CZ ARG A 31 -12.461 23.156-168.287 1.00 39.32 C ATOM 427 NH1 ARG A 31 -13.012 22.089-168.852 1.00 38.08 N ATOM 428 NH2 ARG A 31 -11.382 23.010-167.530 1.00 40.47 N ATOM 429 N SER A 32 -14.879 26.027-173.801 1.00 46.91 N ATOM 430 CA SER A 32 -16.082 25.718-174.567 1.00 47.81 C ATOM 431 C SER A 32 -15.809 25.140-175.966 1.00 46.74 C ATOM 432 O SER A 32 -16.525 24.253-176.427 1.00 47.65 O ATOM 433 CB SER A 32 -16.943 26.978-174.680 1.00 45.02 C ATOM 434 OG SER A 32 -18.062 26.753-175.515 1.00 47.41 O ATOM 435 N HIS A 33 -14.775 25.641-176.637 1.00 37.37 N ATOM 436 CA HIS A 33 -14.423 25.169-177.981 1.00 37.49 C ATOM 437 C HIS A 33 -13.717 23.807-177.973 1.00 37.46 C ATOM 438 O HIS A 33 -14.165 22.842-178.600 1.00 38.10 O ATOM 439 CB HIS A 33 -13.507 26.185-178.670 1.00 30.95 C ATOM 440 CG HIS A 33 -13.035 25.753-180.026 1.00 33.70 C ATOM 441 ND1 HIS A 33 -13.762 25.978-181.174 1.00 33.48 N ATOM 442 CD2 HIS A 33 -11.932 25.064-180.408 1.00 33.26 C ATOM 443 CE1 HIS A 33 -13.129 25.446-182.206 1.00 35.65 C ATOM 444 NE2 HIS A 33 -12.016 24.885-181.768 1.00 34.33 N ATOM 445 N PHE A 34 -12.605 23.738-177.255 1.00 32.95 N ATOM 446 CA PHE A 34 -11.822 22.519-177.202 1.00 33.01 C ATOM 447 C PHE A 34 -12.442 21.347-176.451 1.00 32.53 C ATOM 448 O PHE A 34 -12.007 20.203-176.616 1.00 33.21 O ATOM 449 CB PHE A 34 -10.418 22.862-176.692 1.00 27.02 C ATOM 450 CG PHE A 34 -9.586 23.595-177.721 1.00 29.15 C ATOM 451 CD1 PHE A 34 -9.107 22.920-178.846 1.00 28.37 C ATOM 452 CD2 PHE A 34 -9.366 24.968-177.617 1.00 28.38 C ATOM 453 CE1 PHE A 34 -8.423 23.607-179.862 1.00 29.21 C ATOM 454 CE2 PHE A 34 -8.687 25.670-178.619 1.00 29.56 C ATOM 455 CZ PHE A 34 -8.215 24.988-179.747 1.00 27.44 C ATOM 456 N GLU A 35 -13.471 21.609-175.651 1.00 36.84 N ATOM 457 CA GLU A 35 -14.129 20.515-174.942 1.00 37.55 C ATOM 458 C GLU A 35 -14.836 19.628-175.955 1.00 37.48 C ATOM 459 O GLU A 35 -15.233 18.513-175.636 1.00 36.44 O ATOM 460 CB GLU A 35 -15.154 21.034-173.931 1.00 43.89 C ATOM 461 CG GLU A 35 -14.548 21.633-172.673 1.00 47.83 C ATOM 462 CD GLU A 35 -15.566 21.788-171.546 1.00 48.73 C ATOM 463 OE1 GLU A 35 -16.693 22.257-171.826 1.00 51.27 O ATOM 464 OE2 GLU A 35 -15.232 21.447-170.385 1.00 47.99 O ATOM 465 N GLN A 36 -14.986 20.135-177.177 1.00 27.29 N ATOM 466 CA GLN A 36 -15.646 19.401-178.252 1.00 28.10 C ATOM 467 C GLN A 36 -14.868 18.165-178.670 1.00 29.13 C ATOM 468 O GLN A 36 -15.369 17.346-179.434 1.00 29.61 O ATOM 469 CB GLN A 36 -15.820 20.296-179.484 1.00 45.13 C ATOM 470 CG GLN A 36 -16.779 21.463-179.303 1.00 47.85 C ATOM 471 CD GLN A 36 -16.856 22.358-180.535 1.00 50.79 C ATOM 472 OE1 GLN A 36 -15.869 22.976-180.938 1.00 49.09 O ATOM 473 NE2 GLN A 36 -18.033 22.428-181.137 1.00 51.21 N ATOM 474 N TRP A 37 -13.642 18.031-178.177 1.00 40.40 N ATOM 475 CA TRP A 37 -12.807 16.893-178.537 1.00 40.25 C ATOM 476 C TRP A 37 -12.310 16.111-177.343 1.00 40.11 C ATOM 477 O TRP A 37 -11.374 15.331-177.463 1.00 39.44 O ATOM 478 CB TRP A 37 -11.618 17.367-179.379 1.00 26.34 C ATOM 479 CG TRP A 37 -12.047 17.869-180.707 1.00 28.01 C ATOM 480 CD1 TRP A 37 -12.400 17.118-181.792 1.00 28.69 C ATOM 481 CD2 TRP A 37 -12.281 19.233-181.068 1.00 27.99 C ATOM 482 NE1 TRP A 37 -12.847 17.929-182.804 1.00 30.99 N ATOM 483 CE2 TRP A 37 -12.787 19.233-182.386 1.00 29.15 C ATOM 484 CE3 TRP A 37 -12.118 20.457-180.402 1.00 26.40 C ATOM 485 CZ2 TRP A 37 -13.134 20.411-183.054 1.00 27.87 C ATOM 486 CZ3 TRP A 37 -12.460 21.627-181.063 1.00 24.74 C ATOM 487 CH2 TRP A 37 -12.964 21.595-182.378 1.00 26.56 C ATOM 488 N GLY A 38 -12.931 16.326-176.187 1.00 35.12 N ATOM 489 CA GLY A 38 -12.526 15.592-175.003 1.00 36.05 C ATOM 490 C GLY A 38 -12.674 16.311-173.677 1.00 35.28 C ATOM 491 O GLY A 38 -13.130 17.449-173.611 1.00 36.84 O ATOM 492 N THR A 39 -12.274 15.620-172.616 1.00 29.77 N ATOM 493 CA THR A 39 -12.332 16.137-171.261 1.00 30.79 C ATOM 494 C THR A 39 -11.112 17.010-170.992 1.00 30.98 C ATOM 495 O THR A 39 -9.974 16.539-171.087 1.00 31.36 O ATOM 496 CB THR A 39 -12.326 14.984-170.234 1.00 32.28 C ATOM 497 OG1 THR A 39 -13.479 14.157-170.435 1.00 33.57 O ATOM 498 CG2 THR A 39 -12.317 15.530-168.812 1.00 34.78 C ATOM 499 N LEU A 40 -11.348 18.277-170.660 1.00 33.32 N ATOM 500 CA LEU A 40 -10.254 19.192-170.365 1.00 32.64 C ATOM 501 C LEU A 40 -9.959 19.180-168.879 1.00 33.26 C ATOM 502 O LEU A 40 -10.847 19.404-168.053 1.00 33.56 O ATOM 503 CB LEU A 40 -10.598 20.617-170.800 1.00 37.60 C ATOM 504 CG LEU A 40 -10.660 20.895-172.301 1.00 36.13 C ATOM 505 CD1 LEU A 40 -10.958 22.362-172.518 1.00 38.22 C ATOM 506 CD2 LEU A 40 -9.341 20.526-172.957 1.00 37.22 C ATOM 507 N THR A 41 -8.704 18.920-168.538 1.00 40.38 N ATOM 508 CA THR A 41 -8.292 18.876-167.146 1.00 39.52 C ATOM 509 C THR A 41 -7.690 20.220-166.754 1.00 38.93 C ATOM 510 O THR A 41 -7.421 20.479-165.577 1.00 38.61 O ATOM 511 CB THR A 41 -7.250 17.764-166.919 1.00 34.30 C ATOM 512 OG1 THR A 41 -6.017 18.116-167.564 1.00 30.93 O ATOM 513 CG2 THR A 41 -7.757 16.450-167.501 1.00 34.73 C ATOM 514 N ASP A 42 -7.485 21.074-167.752 1.00 32.39 N ATOM 515 CA ASP A 42 -6.911 22.397-167.535 1.00 32.11 C ATOM 516 C ASP A 42 -7.205 23.230-168.780 1.00 32.97 C ATOM 517 O ASP A 42 -7.307 22.700-169.887 1.00 29.56 O ATOM 518 CB ASP A 42 -5.400 22.265-167.304 1.00 32.50 C ATOM 519 CG ASP A 42 -4.757 23.547-166.792 1.00 33.53 C ATOM 520 OD1 ASP A 42 -5.478 24.455-166.329 1.00 34.65 O ATOM 521 OD2 ASP A 42 -3.513 23.637-166.841 1.00 31.23 O ATOM 522 N CYS A 43 -7.368 24.533-168.595 1.00 31.59 N ATOM 523 CA CYS A 43 -7.653 25.425-169.709 1.00 32.85 C ATOM 524 C CYS A 43 -7.411 26.827-169.200 1.00 33.06 C ATOM 525 O CYS A 43 -7.988 27.243-168.199 1.00 33.03 O ATOM 526 CB CYS A 43 -9.105 25.256-170.160 1.00 27.53 C ATOM 527 SG CYS A 43 -9.559 26.185-171.634 1.00 29.86 S ATOM 528 N VAL A 44 -6.549 27.566-169.877 1.00 25.60 N ATOM 529 CA VAL A 44 -6.258 28.898-169.400 1.00 27.39 C ATOM 530 C VAL A 44 -5.665 29.819-170.457 1.00 28.08 C ATOM 531 O VAL A 44 -4.988 29.381-171.390 1.00 24.53 O ATOM 532 CB VAL A 44 -5.302 28.819-168.181 1.00 34.92 C ATOM 533 CG1 VAL A 44 -4.053 28.028-168.553 1.00 35.36 C ATOM 534 CG2 VAL A 44 -4.939 30.216-167.700 1.00 36.55 C ATOM 535 N VAL A 45 -5.954 31.104-170.286 1.00 20.39 N ATOM 536 CA VAL A 45 -5.480 32.166-171.159 1.00 21.80 C ATOM 537 C VAL A 45 -4.471 32.950-170.335 1.00 23.33 C ATOM 538 O VAL A 45 -4.794 33.440-169.250 1.00 23.15 O ATOM 539 CB VAL A 45 -6.636 33.111-171.575 1.00 26.01 C ATOM 540 CG1 VAL A 45 -6.098 34.262-172.412 1.00 25.30 C ATOM 541 CG2 VAL A 45 -7.669 32.353-172.363 1.00 25.37 C ATOM 542 N MET A 46 -3.244 33.044-170.836 1.00 34.65 N ATOM 543 CA MET A 46 -2.198 33.777-170.134 1.00 37.64 C ATOM 544 C MET A 46 -2.428 35.265-170.303 1.00 38.66 C ATOM 545 O MET A 46 -2.620 35.749-171.416 1.00 38.44 O ATOM 546 CB MET A 46 -0.817 33.391-170.671 1.00 40.11 C ATOM 547 CG MET A 46 -0.148 32.248-169.914 1.00 42.28 C ATOM 548 SD MET A 46 -1.211 30.815-169.600 1.00 42.93 S ATOM 549 CE MET A 46 -0.616 30.306-168.004 1.00 44.31 C ATOM 550 N ARG A 47 -2.423 35.983-169.185 1.00 52.20 N ATOM 551 CA ARG A 47 -2.642 37.422-169.191 1.00 54.57 C ATOM 552 C ARG A 47 -1.482 38.143-168.518 1.00 56.09 C ATOM 553 O ARG A 47 -0.661 37.525-167.839 1.00 56.85 O ATOM 554 CB ARG A 47 -3.950 37.763-168.463 1.00 44.09 C ATOM 555 CG ARG A 47 -5.208 37.189-169.114 1.00 45.22 C ATOM 556 CD ARG A 47 -6.473 37.831-168.550 1.00 44.56 C ATOM 557 NE ARG A 47 -7.644 37.579-169.388 1.00 45.97 N ATOM 558 CZ ARG A 47 -8.350 36.451-169.371 1.00 45.35 C ATOM 559 NH1 ARG A 47 -8.006 35.461-168.551 1.00 47.83 N ATOM 560 NH2 ARG A 47 -9.400 36.309-170.174 1.00 47.18 N ATOM 561 N ASP A 48 -1.416 39.455-168.720 1.00 61.09 N ATOM 562 CA ASP A 48 -0.370 40.264-168.111 1.00 63.28 C ATOM 563 C ASP A 48 -0.692 40.411-166.627 1.00 64.03 C ATOM 564 O ASP A 48 -1.832 40.684-166.257 1.00 63.64 O ATOM 565 CB ASP A 48 -0.317 41.646-168.761 1.00 90.59 C ATOM 566 CG ASP A 48 0.735 42.538-168.136 1.00 91.44 C ATOM 567 OD1 ASP A 48 1.931 42.195-168.228 1.00 92.62 O ATOM 568 OD2 ASP A 48 0.366 43.577-167.549 1.00 93.29 O ATOM 569 N PRO A 49 0.311 40.225-165.758 1.00 71.19 N ATOM 570 CA PRO A 49 0.113 40.340-164.311 1.00 71.47 C ATOM 571 C PRO A 49 -0.643 41.601-163.896 1.00 72.41 C ATOM 572 O PRO A 49 -1.611 41.534-163.135 1.00 72.98 O ATOM 573 CB PRO A 49 1.539 40.311-163.772 1.00 71.50 C ATOM 574 CG PRO A 49 2.221 39.387-164.727 1.00 71.51 C ATOM 575 CD PRO A 49 1.709 39.875-166.067 1.00 71.18 C ATOM 576 N ASN A 50 -0.203 42.748-164.405 1.00 89.85 N ATOM 577 CA ASN A 50 -0.835 44.019-164.076 1.00 89.90 C ATOM 578 C ASN A 50 -2.080 44.295-164.912 1.00 88.87 C ATOM 579 O ASN A 50 -3.203 44.103-164.447 1.00 89.40 O ATOM 580 CB ASN A 50 0.166 45.163-164.245 1.00101.65 C ATOM 581 CG ASN A 50 1.305 45.092-163.245 1.00103.22 C ATOM 582 OD1 ASN A 50 2.094 44.148-163.250 1.00102.64 O ATOM 583 ND2 ASN A 50 1.391 46.093-162.376 1.00103.52 N ATOM 584 N THR A 51 -1.876 44.745-166.146 1.00 56.32 N ATOM 585 CA THR A 51 -2.983 45.060-167.045 1.00 54.76 C ATOM 586 C THR A 51 -4.033 43.946-167.137 1.00 55.04 C ATOM 587 O THR A 51 -5.161 44.189-167.565 1.00 54.81 O ATOM 588 CB THR A 51 -2.471 45.376-168.480 1.00 61.26 C ATOM 589 OG1 THR A 51 -1.910 44.196-169.071 1.00 61.92 O ATOM 590 CG2 THR A 51 -1.406 46.465-168.438 1.00 61.58 C ATOM 591 N LYS A 52 -3.661 42.731-166.739 1.00 86.21 N ATOM 592 CA LYS A 52 -4.570 41.584-166.787 1.00 85.40 C ATOM 593 C LYS A 52 -5.080 41.323-168.203 1.00 83.97 C ATOM 594 O LYS A 52 -6.020 40.553-168.399 1.00 84.38 O ATOM 595 CB LYS A 52 -5.766 41.808-165.858 1.00 75.42 C ATOM 596 CG LYS A 52 -5.425 41.851-164.382 1.00 76.47 C ATOM 597 CD LYS A 52 -5.013 40.489-163.856 1.00 77.14 C ATOM 598 CE LYS A 52 -4.765 40.553-162.358 1.00 77.44 C ATOM 599 NZ LYS A 52 -4.382 39.237-161.793 1.00 78.19 N ATOM 600 N ARG A 53 -4.459 41.971-169.184 1.00 37.96 N ATOM 601 CA ARG A 53 -4.851 41.812-170.577 1.00 36.94 C ATOM 602 C ARG A 53 -4.327 40.481-171.114 1.00 34.77 C ATOM 603 O ARG A 53 -3.323 39.952-170.631 1.00 34.89 O ATOM 604 CB ARG A 53 -4.293 42.968-171.416 1.00125.80 C ATOM 605 CG ARG A 53 -5.289 43.572-172.403 1.00128.74 C ATOM 606 CD ARG A 53 -5.615 42.640-173.563 1.00129.60 C ATOM 607 NE ARG A 53 -4.522 42.555-174.528 1.00131.14 N ATOM 608 CZ ARG A 53 -4.583 41.877-175.671 1.00131.03 C ATOM 609 NH1 ARG A 53 -5.687 41.219-175.997 1.00131.21 N ATOM 610 NH2 ARG A 53 -3.541 41.858-176.490 1.00130.40 N ATOM 611 N SER A 54 -5.011 39.939-172.113 1.00 41.20 N ATOM 612 CA SER A 54 -4.596 38.677-172.702 1.00 38.74 C ATOM 613 C SER A 54 -3.269 38.832-173.424 1.00 37.99 C ATOM 614 O SER A 54 -3.006 39.857-174.045 1.00 38.16 O ATOM 615 CB SER A 54 -5.646 38.175-173.690 1.00 39.76 C ATOM 616 OG SER A 54 -5.240 36.943-174.267 1.00 37.43 O ATOM 617 N ARG A 55 -2.429 37.812-173.338 1.00 31.01 N ATOM 618 CA ARG A 55 -1.149 37.844-174.014 1.00 31.40 C ATOM 619 C ARG A 55 -1.298 37.184-175.381 1.00 30.66 C ATOM 620 O ARG A 55 -0.319 36.962-176.087 1.00 30.94 O ATOM 621 CB ARG A 55 -0.099 37.133-173.171 1.00 38.44 C ATOM 622 CG ARG A 55 0.228 37.872-171.886 1.00 38.70 C ATOM 623 CD ARG A 55 1.301 37.142-171.112 1.00 39.97 C ATOM 624 NE ARG A 55 2.463 36.879-171.953 1.00 38.43 N ATOM 625 CZ ARG A 55 3.492 36.127-171.584 1.00 39.82 C ATOM 626 NH1 ARG A 55 3.503 35.564-170.384 1.00 38.46 N ATOM 627 NH2 ARG A 55 4.504 35.931-172.423 1.00 40.31 N ATOM 628 N GLY A 56 -2.540 36.871-175.740 1.00 27.18 N ATOM 629 CA GLY A 56 -2.824 36.275-177.033 1.00 25.60 C ATOM 630 C GLY A 56 -2.441 34.821-177.185 1.00 25.28 C ATOM 631 O GLY A 56 -2.162 34.359-178.295 1.00 25.33 O ATOM 632 N PHE A 57 -2.419 34.085-176.080 1.00 30.27 N ATOM 633 CA PHE A 57 -2.075 32.678-176.157 1.00 29.62 C ATOM 634 C PHE A 57 -2.528 31.963-174.906 1.00 30.82 C ATOM 635 O PHE A 57 -2.758 32.586-173.875 1.00 31.31 O ATOM 636 CB PHE A 57 -0.565 32.512-176.388 1.00 29.13 C ATOM 637 CG PHE A 57 0.273 32.650-175.154 1.00 29.26 C ATOM 638 CD1 PHE A 57 0.520 31.550-174.339 1.00 28.52 C ATOM 639 CD2 PHE A 57 0.842 33.877-174.816 1.00 28.83 C ATOM 640 CE1 PHE A 57 1.323 31.668-173.208 1.00 26.58 C ATOM 641 CE2 PHE A 57 1.650 34.008-173.680 1.00 28.64 C ATOM 642 CZ PHE A 57 1.889 32.901-172.877 1.00 27.49 C ATOM 643 N GLY A 58 -2.673 30.650-174.994 1.00 27.55 N ATOM 644 CA GLY A 58 -3.124 29.910-173.836 1.00 26.93 C ATOM 645 C GLY A 58 -2.784 28.447-173.901 1.00 25.38 C ATOM 646 O GLY A 58 -1.980 28.024-174.724 1.00 24.49 O ATOM 647 N PHE A 59 -3.402 27.670-173.023 1.00 23.19 N ATOM 648 CA PHE A 59 -3.154 26.236-172.980 1.00 22.38 C ATOM 649 C PHE A 59 -4.433 25.481-172.639 1.00 21.75 C ATOM 650 O PHE A 59 -5.263 25.977-171.876 1.00 23.27 O ATOM 651 CB PHE A 59 -2.117 25.896-171.900 1.00 19.01 C ATOM 652 CG PHE A 59 -0.723 26.402-172.178 1.00 19.70 C ATOM 653 CD1 PHE A 59 -0.306 27.634-171.697 1.00 20.57 C ATOM 654 CD2 PHE A 59 0.191 25.610-172.868 1.00 18.96 C ATOM 655 CE1 PHE A 59 1.014 28.077-171.890 1.00 21.64 C ATOM 656 CE2 PHE A 59 1.504 26.035-173.068 1.00 19.28 C ATOM 657 CZ PHE A 59 1.920 27.279-172.573 1.00 18.31 C ATOM 658 N VAL A 60 -4.588 24.297-173.224 1.00 30.44 N ATOM 659 CA VAL A 60 -5.715 23.413-172.940 1.00 30.74 C ATOM 660 C VAL A 60 -5.062 22.046-172.726 1.00 31.51 C ATOM 661 O VAL A 60 -4.102 21.689-173.412 1.00 30.10 O ATOM 662 CB VAL A 60 -6.772 23.351-174.103 1.00 22.07 C ATOM 663 CG1 VAL A 60 -7.371 24.728-174.317 1.00 21.19 C ATOM 664 CG2 VAL A 60 -6.147 22.828-175.393 1.00 22.65 C ATOM 665 N THR A 61 -5.556 21.300-171.753 1.00 27.73 N ATOM 666 CA THR A 61 -4.988 20.001-171.441 1.00 26.68 C ATOM 667 C THR A 61 -6.110 18.985-171.333 1.00 28.08 C ATOM 668 O THR A 61 -7.082 19.213-170.613 1.00 29.48 O ATOM 669 CB THR A 61 -4.218 20.051-170.100 1.00 21.12 C ATOM 670 OG1 THR A 61 -3.187 21.042-170.180 1.00 19.95 O ATOM 671 CG2 THR A 61 -3.588 18.711-169.788 1.00 21.48 C ATOM 672 N TYR A 62 -5.971 17.872-172.048 1.00 25.36 N ATOM 673 CA TYR A 62 -6.982 16.825-172.037 1.00 25.92 C ATOM 674 C TYR A 62 -6.638 15.719-171.057 1.00 24.63 C ATOM 675 O TYR A 62 -5.521 15.653-170.553 1.00 23.93 O ATOM 676 CB TYR A 62 -7.146 16.224-173.438 1.00 25.52 C ATOM 677 CG TYR A 62 -7.741 17.173-174.459 1.00 26.89 C ATOM 678 CD1 TYR A 62 -6.928 17.984-175.252 1.00 26.48 C ATOM 679 CD2 TYR A 62 -9.124 17.252-174.636 1.00 28.46 C ATOM 680 CE1 TYR A 62 -7.480 18.849-176.199 1.00 28.16 C ATOM 681 CE2 TYR A 62 -9.685 18.112-175.580 1.00 26.06 C ATOM 682 CZ TYR A 62 -8.862 18.906-176.356 1.00 28.38 C ATOM 683 OH TYR A 62 -9.423 19.755-177.284 1.00 27.85 O ATOM 684 N ALA A 63 -7.605 14.846-170.789 1.00 42.73 N ATOM 685 CA ALA A 63 -7.388 13.739-169.868 1.00 41.59 C ATOM 686 C ALA A 63 -6.546 12.668-170.543 1.00 41.38 C ATOM 687 O ALA A 63 -5.967 11.812-169.878 1.00 40.94 O ATOM 688 CB ALA A 63 -8.726 13.147-169.417 1.00 25.32 C ATOM 689 N THR A 64 -6.464 12.721-171.865 1.00 33.76 N ATOM 690 CA THR A 64 -5.695 11.714-172.596 1.00 36.04 C ATOM 691 C THR A 64 -5.031 12.262-173.852 1.00 35.60 C ATOM 692 O THR A 64 -5.510 13.219-174.453 1.00 35.25 O ATOM 693 CB THR A 64 -6.587 10.559-173.056 1.00 28.23 C ATOM 694 OG1 THR A 64 -7.511 11.051-174.034 1.00 29.29 O ATOM 695 CG2 THR A 64 -7.355 9.973-171.894 1.00 30.34 C ATOM 696 N VAL A 65 -3.935 11.630-174.256 1.00 25.55 N ATOM 697 CA VAL A 65 -3.221 12.048-175.454 1.00 27.67 C ATOM 698 C VAL A 65 -4.083 11.750-176.666 1.00 27.84 C ATOM 699 O VAL A 65 -4.009 12.444-177.678 1.00 27.09 O ATOM 700 CB VAL A 65 -1.886 11.313-175.585 1.00 20.29 C ATOM 701 CG1 VAL A 65 -1.189 11.708-176.882 1.00 21.10 C ATOM 702 CG2 VAL A 65 -1.004 11.651-174.385 1.00 25.93 C ATOM 703 N GLU A 66 -4.916 10.722-176.557 1.00 28.99 N ATOM 704 CA GLU A 66 -5.802 10.356-177.659 1.00 31.69 C ATOM 705 C GLU A 66 -6.699 11.547-178.004 1.00 30.78 C ATOM 706 O GLU A 66 -6.951 11.828-179.174 1.00 28.69 O ATOM 707 CB GLU A 66 -6.664 9.156-177.273 1.00 62.14 C ATOM 708 CG GLU A 66 -7.463 8.592-178.428 1.00 67.01 C ATOM 709 CD GLU A 66 -8.438 7.523-177.990 1.00 70.48 C ATOM 710 OE1 GLU A 66 -8.000 6.524-177.382 1.00 72.27 O ATOM 711 OE2 GLU A 66 -9.648 7.682-178.257 1.00 71.37 O ATOM 712 N GLU A 67 -7.177 12.237-176.971 1.00 37.75 N ATOM 713 CA GLU A 67 -8.025 13.405-177.156 1.00 37.85 C ATOM 714 C GLU A 67 -7.199 14.546-177.747 1.00 38.62 C ATOM 715 O GLU A 67 -7.688 15.303-178.585 1.00 38.17 O ATOM 716 CB GLU A 67 -8.646 13.816-175.817 1.00 40.53 C ATOM 717 CG GLU A 67 -9.807 12.932-175.387 1.00 41.88 C ATOM 718 CD GLU A 67 -9.933 12.809-173.877 1.00 44.94 C ATOM 719 OE1 GLU A 67 -10.047 13.841-173.180 1.00 48.44 O ATOM 720 OE2 GLU A 67 -9.919 11.666-173.379 1.00 45.34 O ATOM 721 N VAL A 68 -5.948 14.678-177.312 1.00 26.34 N ATOM 722 CA VAL A 68 -5.081 15.721-177.860 1.00 25.13 C ATOM 723 C VAL A 68 -4.942 15.483-179.355 1.00 25.00 C ATOM 724 O VAL A 68 -5.066 16.411-180.163 1.00 24.78 O ATOM 725 CB VAL A 68 -3.651 15.683-177.272 1.00 21.30 C ATOM 726 CG1 VAL A 68 -2.805 16.755-177.932 1.00 21.01 C ATOM 727 CG2 VAL A 68 -3.684 15.886-175.765 1.00 18.76 C ATOM 728 N ASP A 69 -4.673 14.233-179.724 1.00 23.52 N ATOM 729 CA ASP A 69 -4.506 13.895-181.129 1.00 25.24 C ATOM 730 C ASP A 69 -5.770 14.193-181.917 1.00 25.62 C ATOM 731 O ASP A 69 -5.699 14.627-183.056 1.00 26.15 O ATOM 732 CB ASP A 69 -4.127 12.426-181.302 1.00 27.62 C ATOM 733 CG ASP A 69 -2.714 12.127-180.834 1.00 31.87 C ATOM 734 OD1 ASP A 69 -1.811 12.970-181.016 1.00 29.35 O ATOM 735 OD2 ASP A 69 -2.501 11.029-180.297 1.00 32.70 O ATOM 736 N ALA A 70 -6.923 13.958-181.303 1.00 25.01 N ATOM 737 CA ALA A 70 -8.194 14.216-181.961 1.00 26.31 C ATOM 738 C ALA A 70 -8.292 15.717-182.236 1.00 24.96 C ATOM 739 O ALA A 70 -8.638 16.140-183.339 1.00 24.95 O ATOM 740 CB ALA A 70 -9.345 13.756-181.071 1.00 26.36 C ATOM 741 N ALA A 71 -7.966 16.520-181.229 1.00 32.78 N ATOM 742 CA ALA A 71 -8.013 17.969-181.365 1.00 30.43 C ATOM 743 C ALA A 71 -7.099 18.432-182.498 1.00 29.09 C ATOM 744 O ALA A 71 -7.506 19.230-183.339 1.00 28.28 O ATOM 745 CB ALA A 71 -7.608 18.627-180.059 1.00 21.53 C ATOM 746 N MET A 72 -5.869 17.927-182.530 1.00 23.08 N ATOM 747 CA MET A 72 -4.940 18.312-183.585 1.00 24.00 C ATOM 748 C MET A 72 -5.461 17.873-184.945 1.00 26.24 C ATOM 749 O MET A 72 -5.317 18.599-185.929 1.00 26.05 O ATOM 750 CB MET A 72 -3.548 17.724-183.337 1.00 20.39 C ATOM 751 CG MET A 72 -2.773 18.406-182.196 1.00 19.92 C ATOM 752 SD MET A 72 -2.737 20.226-182.318 1.00 22.82 S ATOM 753 CE MET A 72 -1.527 20.480-183.633 1.00 21.37 C ATOM 754 N ASN A 73 -6.078 16.698-185.008 1.00 29.50 N ATOM 755 CA ASN A 73 -6.618 16.220-186.279 1.00 31.59 C ATOM 756 C ASN A 73 -7.811 17.075-186.730 1.00 33.73 C ATOM 757 O ASN A 73 -8.220 17.027-187.893 1.00 35.34 O ATOM 758 CB ASN A 73 -7.039 14.747-186.176 1.00 49.81 C ATOM 759 CG ASN A 73 -5.850 13.809-186.037 1.00 52.93 C ATOM 760 OD1 ASN A 73 -4.868 13.921-186.773 1.00 55.10 O ATOM 761 ND2 ASN A 73 -5.937 12.873-185.097 1.00 53.83 N ATOM 762 N ALA A 74 -8.342 17.874-185.805 1.00 29.59 N ATOM 763 CA ALA A 74 -9.490 18.724-186.095 1.00 29.62 C ATOM 764 C ALA A 74 -9.125 20.115-186.602 1.00 29.09 C ATOM 765 O ALA A 74 -9.987 20.976-186.718 1.00 28.99 O ATOM 766 CB ALA A 74 -10.384 18.831-184.854 1.00 35.30 C ATOM 767 N ARG A 75 -7.851 20.338-186.905 1.00 32.30 N ATOM 768 CA ARG A 75 -7.421 21.636-187.416 1.00 32.34 C ATOM 769 C ARG A 75 -8.029 21.837-188.801 1.00 33.25 C ATOM 770 O ARG A 75 -8.314 20.871-189.500 1.00 33.59 O ATOM 771 CB ARG A 75 -5.892 21.696-187.513 1.00 34.59 C ATOM 772 CG ARG A 75 -5.161 21.792-186.175 1.00 33.40 C ATOM 773 CD ARG A 75 -3.671 21.526-186.370 1.00 31.06 C ATOM 774 NE ARG A 75 -3.421 20.127-186.731 1.00 30.55 N ATOM 775 CZ ARG A 75 -2.316 19.677-187.325 1.00 29.18 C ATOM 776 NH1 ARG A 75 -1.335 20.511-187.645 1.00 28.26 N ATOM 777 NH2 ARG A 75 -2.187 18.382-187.593 1.00 28.67 N ATOM 778 N PRO A 76 -8.240 23.093-189.214 1.00 31.41 N ATOM 779 CA PRO A 76 -7.939 24.311-188.452 1.00 31.39 C ATOM 780 C PRO A 76 -8.996 24.635-187.392 1.00 30.65 C ATOM 781 O PRO A 76 -10.174 24.293-187.536 1.00 30.38 O ATOM 782 CB PRO A 76 -7.866 25.380-189.539 1.00 29.01 C ATOM 783 CG PRO A 76 -8.930 24.901-190.514 1.00 30.13 C ATOM 784 CD PRO A 76 -8.641 23.422-190.596 1.00 28.06 C ATOM 785 N HIS A 77 -8.556 25.306-186.336 1.00 31.20 N ATOM 786 CA HIS A 77 -9.424 25.696-185.237 1.00 30.49 C ATOM 787 C HIS A 77 -9.701 27.197-185.220 1.00 30.24 C ATOM 788 O HIS A 77 -8.780 28.010-185.220 1.00 30.46 O ATOM 789 CB HIS A 77 -8.783 25.289-183.904 1.00 27.00 C ATOM 790 CG HIS A 77 -8.858 23.821-183.618 1.00 25.30 C ATOM 791 ND1 HIS A 77 -9.996 23.215-183.132 1.00 23.08 N ATOM 792 CD2 HIS A 77 -7.937 22.837-183.747 1.00 24.32 C ATOM 793 CE1 HIS A 77 -9.773 21.922-182.970 1.00 23.91 C ATOM 794 NE2 HIS A 77 -8.531 21.667-183.336 1.00 23.38 N ATOM 795 N LYS A 78 -10.976 27.562-185.214 1.00 26.89 N ATOM 796 CA LYS A 78 -11.354 28.967-185.147 1.00 27.67 C ATOM 797 C LYS A 78 -12.031 29.145-183.794 1.00 28.24 C ATOM 798 O LYS A 78 -13.030 28.484-183.492 1.00 29.30 O ATOM 799 CB LYS A 78 -12.317 29.330-186.279 1.00 41.45 C ATOM 800 CG LYS A 78 -12.576 30.822-186.395 1.00 42.76 C ATOM 801 CD LYS A 78 -12.986 31.212-187.810 1.00 46.54 C ATOM 802 CE LYS A 78 -14.386 30.721-188.163 1.00 47.99 C ATOM 803 NZ LYS A 78 -15.446 31.484-187.435 1.00 49.47 N ATOM 804 N VAL A 79 -11.465 30.011-182.963 1.00 28.45 N ATOM 805 CA VAL A 79 -12.016 30.249-181.639 1.00 27.60 C ATOM 806 C VAL A 79 -12.341 31.718-181.526 1.00 27.86 C ATOM 807 O VAL A 79 -11.473 32.564-181.726 1.00 26.76 O ATOM 808 CB VAL A 79 -11.006 29.864-180.527 1.00 29.64 C ATOM 809 CG1 VAL A 79 -11.663 29.988-179.148 1.00 29.52 C ATOM 810 CG2 VAL A 79 -10.499 28.451-180.756 1.00 28.20 C ATOM 811 N ASP A 80 -13.596 32.015-181.214 1.00 30.04 N ATOM 812 CA ASP A 80 -14.051 33.392-181.089 1.00 29.37 C ATOM 813 C ASP A 80 -13.808 34.200-182.379 1.00 29.58 C ATOM 814 O ASP A 80 -13.406 35.372-182.329 1.00 29.14 O ATOM 815 CB ASP A 80 -13.369 34.075-179.887 1.00 33.94 C ATOM 816 CG ASP A 80 -13.795 33.476-178.552 1.00 36.85 C ATOM 817 OD1 ASP A 80 -15.007 33.236-178.382 1.00 35.27 O ATOM 818 OD2 ASP A 80 -12.930 33.255-177.671 1.00 34.76 O ATOM 819 N GLY A 81 -14.047 33.556-183.524 1.00 31.31 N ATOM 820 CA GLY A 81 -13.882 34.204-184.816 1.00 32.65 C ATOM 821 C GLY A 81 -12.467 34.412-185.340 1.00 32.23 C ATOM 822 O GLY A 81 -12.285 35.043-186.375 1.00 31.87 O ATOM 823 N ARG A 82 -11.473 33.882-184.636 1.00 32.30 N ATOM 824 CA ARG A 82 -10.069 34.016-185.016 1.00 34.09 C ATOM 825 C ARG A 82 -9.459 32.628-185.192 1.00 32.31 C ATOM 826 O ARG A 82 -9.662 31.749-184.352 1.00 32.42 O ATOM 827 CB ARG A 82 -9.323 34.775-183.912 1.00 29.51 C ATOM 828 CG ARG A 82 -7.801 34.898-184.059 1.00 34.09 C ATOM 829 CD ARG A 82 -7.407 35.842-185.175 1.00 34.52 C ATOM 830 NE ARG A 82 -6.055 36.386-185.017 1.00 37.40 N ATOM 831 CZ ARG A 82 -4.937 35.664-185.020 1.00 39.10 C ATOM 832 NH1 ARG A 82 -4.978 34.348-185.169 1.00 39.58 N ATOM 833 NH2 ARG A 82 -3.767 36.262-184.880 1.00 40.38 N ATOM 834 N VAL A 83 -8.727 32.418-186.282 1.00 25.35 N ATOM 835 CA VAL A 83 -8.096 31.122-186.491 1.00 24.78 C ATOM 836 C VAL A 83 -6.900 31.084-185.548 1.00 23.40 C ATOM 837 O VAL A 83 -6.011 31.944-185.622 1.00 24.16 O ATOM 838 CB VAL A 83 -7.596 30.931-187.940 1.00 36.80 C ATOM 839 CG1 VAL A 83 -6.962 29.559-188.086 1.00 38.77 C ATOM 840 CG2 VAL A 83 -8.756 31.059-188.916 1.00 36.27 C ATOM 841 N VAL A 84 -6.896 30.097-184.653 1.00 30.74 N ATOM 842 CA VAL A 84 -5.822 29.944-183.681 1.00 29.12 C ATOM 843 C VAL A 84 -4.803 28.912-184.168 1.00 29.61 C ATOM 844 O VAL A 84 -5.060 28.197-185.136 1.00 29.38 O ATOM 845 CB VAL A 84 -6.386 29.509-182.301 1.00 22.86 C ATOM 846 CG1 VAL A 84 -7.424 30.499-181.837 1.00 24.61 C ATOM 847 CG2 VAL A 84 -6.977 28.118-182.383 1.00 23.35 C ATOM 848 N GLU A 85 -3.648 28.850-183.506 1.00 18.47 N ATOM 849 CA GLU A 85 -2.613 27.890-183.879 1.00 22.16 C ATOM 850 C GLU A 85 -2.245 26.941-182.722 1.00 21.55 C ATOM 851 O GLU A 85 -1.418 27.261-181.865 1.00 23.68 O ATOM 852 CB GLU A 85 -1.377 28.632-184.386 1.00 28.48 C ATOM 853 CG GLU A 85 -0.310 27.724-184.943 1.00 32.96 C ATOM 854 CD GLU A 85 0.774 28.489-185.680 1.00 34.39 C ATOM 855 OE1 GLU A 85 1.044 29.645-185.304 1.00 35.73 O ATOM 856 OE2 GLU A 85 1.368 27.934-186.626 1.00 38.75 O ATOM 857 N PRO A 86 -2.857 25.748-182.697 1.00 26.06 N ATOM 858 CA PRO A 86 -2.598 24.754-181.649 1.00 26.29 C ATOM 859 C PRO A 86 -1.305 23.996-181.906 1.00 25.75 C ATOM 860 O PRO A 86 -1.042 23.573-183.033 1.00 24.42 O ATOM 861 CB PRO A 86 -3.812 23.821-181.727 1.00 22.42 C ATOM 862 CG PRO A 86 -4.719 24.424-182.799 1.00 24.32 C ATOM 863 CD PRO A 86 -3.818 25.223-183.676 1.00 21.95 C ATOM 864 N LYS A 87 -0.513 23.806-180.857 1.00 24.17 N ATOM 865 CA LYS A 87 0.754 23.096-180.982 1.00 23.70 C ATOM 866 C LYS A 87 1.025 22.244-179.750 1.00 23.29 C ATOM 867 O LYS A 87 0.576 22.563-178.654 1.00 19.72 O ATOM 868 CB LYS A 87 1.897 24.096-181.145 1.00 23.36 C ATOM 869 CG LYS A 87 1.645 25.167-182.185 1.00 27.07 C ATOM 870 CD LYS A 87 2.691 26.250-182.077 1.00 28.48 C ATOM 871 CE LYS A 87 2.334 27.451-182.918 1.00 30.90 C ATOM 872 NZ LYS A 87 3.325 28.543-182.735 1.00 31.00 N ATOM 873 N ARG A 88 1.771 21.160-179.929 1.00 18.33 N ATOM 874 CA ARG A 88 2.118 20.316-178.795 1.00 17.17 C ATOM 875 C ARG A 88 2.845 21.234-177.809 1.00 16.35 C ATOM 876 O ARG A 88 3.729 21.990-178.196 1.00 14.94 O ATOM 877 CB ARG A 88 3.045 19.185-179.246 1.00 22.15 C ATOM 878 CG ARG A 88 2.482 18.314-180.376 1.00 21.20 C ATOM 879 CD ARG A 88 1.348 17.399-179.926 1.00 22.10 C ATOM 880 NE ARG A 88 0.659 16.824-181.079 1.00 20.69 N ATOM 881 CZ ARG A 88 -0.178 15.789-181.031 1.00 20.08 C ATOM 882 NH1 ARG A 88 -0.439 15.185-179.878 1.00 19.18 N ATOM 883 NH2 ARG A 88 -0.783 15.376-182.142 1.00 21.88 N ATOM 884 N ALA A 89 2.460 21.191-176.543 1.00 21.18 N ATOM 885 CA ALA A 89 3.099 22.047-175.543 1.00 21.78 C ATOM 886 C ALA A 89 4.561 21.631-175.315 1.00 21.54 C ATOM 887 O ALA A 89 4.837 20.482-175.002 1.00 19.32 O ATOM 888 CB ALA A 89 2.320 21.970-174.237 1.00 20.61 C ATOM 889 N VAL A 90 5.494 22.560-175.473 1.00 19.57 N ATOM 890 CA VAL A 90 6.909 22.244-175.266 1.00 19.73 C ATOM 891 C VAL A 90 7.286 22.624-173.846 1.00 20.31 C ATOM 892 O VAL A 90 7.038 23.744-173.424 1.00 19.48 O ATOM 893 CB VAL A 90 7.804 23.013-176.258 1.00 21.74 C ATOM 894 CG1 VAL A 90 9.275 22.816-175.910 1.00 22.62 C ATOM 895 CG2 VAL A 90 7.534 22.520-177.669 1.00 20.75 C ATOM 896 N SER A 91 7.885 21.698-173.109 1.00 19.64 N ATOM 897 CA SER A 91 8.246 21.963-171.719 1.00 20.97 C ATOM 898 C SER A 91 9.066 23.230-171.559 1.00 22.17 C ATOM 899 O SER A 91 9.773 23.642-172.477 1.00 23.58 O ATOM 900 CB SER A 91 9.032 20.792-171.121 1.00 18.16 C ATOM 901 OG SER A 91 10.367 20.792-171.598 1.00 17.44 O ATOM 902 N ARG A 92 8.967 23.833-170.375 1.00 24.87 N ATOM 903 CA ARG A 92 9.704 25.052-170.057 1.00 24.82 C ATOM 904 C ARG A 92 11.198 24.807-170.263 1.00 26.16 C ATOM 905 O ARG A 92 11.910 25.677-170.745 1.00 26.02 O ATOM 906 CB ARG A 92 9.429 25.472-168.606 1.00 22.26 C ATOM 907 CG ARG A 92 7.998 25.941-168.345 1.00 21.06 C ATOM 908 CD ARG A 92 7.684 25.863-166.865 1.00 21.72 C ATOM 909 NE ARG A 92 6.458 26.540-166.455 1.00 21.37 N ATOM 910 CZ ARG A 92 5.224 26.120-166.713 1.00 21.48 C ATOM 911 NH1 ARG A 92 5.026 25.014-167.407 1.00 20.19 N ATOM 912 NH2 ARG A 92 4.184 26.785-166.220 1.00 21.55 N ATOM 913 N GLU A 93 11.663 23.616-169.902 1.00 21.62 N ATOM 914 CA GLU A 93 13.076 23.260-170.076 1.00 24.92 C ATOM 915 C GLU A 93 13.472 23.278-171.565 1.00 24.92 C ATOM 916 O GLU A 93 14.424 23.951-171.959 1.00 26.79 O ATOM 917 CB GLU A 93 13.355 21.864-169.512 1.00 36.46 C ATOM 918 CG GLU A 93 14.818 21.451-169.613 1.00 39.50 C ATOM 919 CD GLU A 93 15.039 19.957-169.433 1.00 42.37 C ATOM 920 OE1 GLU A 93 14.342 19.333-168.607 1.00 39.28 O ATOM 921 OE2 GLU A 93 15.930 19.404-170.111 1.00 43.18 O ATOM 922 N ASP A 94 12.753 22.525-172.390 1.00 23.72 N ATOM 923 CA ASP A 94 13.061 22.502-173.816 1.00 23.37 C ATOM 924 C ASP A 94 12.794 23.855-174.489 1.00 25.52 C ATOM 925 O ASP A 94 13.410 24.186-175.502 1.00 25.06 O ATOM 926 CB ASP A 94 12.257 21.409-174.518 1.00 27.57 C ATOM 927 CG ASP A 94 12.673 20.011-174.088 1.00 28.46 C ATOM 928 OD1 ASP A 94 13.842 19.824-173.669 1.00 28.92 O ATOM 929 OD2 ASP A 94 11.833 19.095-174.188 1.00 31.03 O ATOM 930 N SER A 95 11.888 24.642-173.920 1.00 22.98 N ATOM 931 CA SER A 95 11.572 25.944-174.499 1.00 24.33 C ATOM 932 C SER A 95 12.802 26.843-174.575 1.00 25.91 C ATOM 933 O SER A 95 12.800 27.850-175.292 1.00 26.45 O ATOM 934 CB SER A 95 10.471 26.634-173.693 1.00 19.27 C ATOM 935 OG SER A 95 9.210 26.052-173.992 1.00 19.32 O ATOM 936 N GLN A 96 13.852 26.466-173.842 1.00 34.04 N ATOM 937 CA GLN A 96 15.101 27.224-173.818 1.00 37.43 C ATOM 938 C GLN A 96 15.919 26.975-175.087 1.00 38.67 C ATOM 939 O GLN A 96 16.494 27.901-175.659 1.00 39.98 O ATOM 940 CB GLN A 96 15.943 26.836-172.596 1.00 43.61 C ATOM 941 CG GLN A 96 15.209 26.910-171.270 1.00 48.39 C ATOM 942 CD GLN A 96 14.501 28.233-171.084 1.00 49.66 C ATOM 943 OE1 GLN A 96 15.132 29.289-171.083 1.00 52.48 O ATOM 944 NE2 GLN A 96 13.180 28.186-170.934 1.00 51.57 N ATOM 945 N ARG A 97 15.968 25.720-175.523 1.00 33.14 N ATOM 946 CA ARG A 97 16.717 25.350-176.718 1.00 34.45 C ATOM 947 C ARG A 97 16.330 26.235-177.899 1.00 33.70 C ATOM 948 O ARG A 97 15.161 26.557-178.088 1.00 32.62 O ATOM 949 CB ARG A 97 16.459 23.882-177.064 1.00 78.82 C ATOM 950 CG ARG A 97 16.947 22.890-176.014 1.00 81.21 C ATOM 951 CD ARG A 97 18.465 22.670-176.063 1.00 85.21 C ATOM 952 NE ARG A 97 19.243 23.879-175.787 1.00 86.81 N ATOM 953 CZ ARG A 97 20.573 23.915-175.712 1.00 88.87 C ATOM 954 NH1 ARG A 97 21.285 22.809-175.891 1.00 89.45 N ATOM 955 NH2 ARG A 97 21.193 25.061-175.462 1.00 89.00 N ATOM 956 N PRO A 98 17.316 26.656-178.703 1.00 38.94 N ATOM 957 CA PRO A 98 17.018 27.506-179.859 1.00 38.48 C ATOM 958 C PRO A 98 16.097 26.850-180.893 1.00 37.92 C ATOM 959 O PRO A 98 16.239 25.667-181.218 1.00 38.45 O ATOM 960 CB PRO A 98 18.404 27.815-180.416 1.00 48.71 C ATOM 961 CG PRO A 98 19.234 27.875-179.179 1.00 49.45 C ATOM 962 CD PRO A 98 18.763 26.648-178.429 1.00 48.34 C ATOM 963 N GLY A 99 15.148 27.636-181.394 1.00 42.20 N ATOM 964 CA GLY A 99 14.211 27.148-182.390 1.00 40.30 C ATOM 965 C GLY A 99 13.143 26.204-181.865 1.00 38.70 C ATOM 966 O GLY A 99 12.303 25.737-182.628 1.00 39.01 O ATOM 967 N ALA A 100 13.161 25.938-180.563 1.00 22.95 N ATOM 968 CA ALA A 100 12.207 25.025-179.950 1.00 23.41 C ATOM 969 C ALA A 100 10.748 25.266-180.339 1.00 21.77 C ATOM 970 O ALA A 100 9.959 24.317-180.420 1.00 21.06 O ATOM 971 CB ALA A 100 12.350 25.078-178.438 1.00 27.16 C ATOM 972 N HIS A 101 10.386 26.521-180.593 1.00 23.31 N ATOM 973 CA HIS A 101 9.003 26.827-180.939 1.00 23.90 C ATOM 974 C HIS A 101 8.709 27.052-182.416 1.00 25.19 C ATOM 975 O HIS A 101 7.581 27.392-182.783 1.00 24.60 O ATOM 976 CB HIS A 101 8.534 28.017-180.107 1.00 23.62 C ATOM 977 CG HIS A 101 8.616 27.769-178.633 1.00 23.76 C ATOM 978 ND1 HIS A 101 8.956 28.750-177.726 1.00 23.28 N ATOM 979 CD2 HIS A 101 8.438 26.635-177.912 1.00 23.42 C ATOM 980 CE1 HIS A 101 8.990 28.230-176.512 1.00 21.69 C ATOM 981 NE2 HIS A 101 8.678 26.949-176.597 1.00 23.78 N ATOM 982 N LEU A 102 9.707 26.834-183.265 1.00 30.99 N ATOM 983 CA LEU A 102 9.527 27.008-184.706 1.00 32.35 C ATOM 984 C LEU A 102 8.563 26.002-185.316 1.00 32.18 C ATOM 985 O LEU A 102 8.468 24.852-184.878 1.00 32.05 O ATOM 986 CB LEU A 102 10.860 26.868-185.445 1.00 35.35 C ATOM 987 CG LEU A 102 11.984 27.853-185.142 1.00 38.20 C ATOM 988 CD1 LEU A 102 13.205 27.466-185.960 1.00 38.15 C ATOM 989 CD2 LEU A 102 11.536 29.272-185.464 1.00 39.89 C ATOM 990 N THR A 103 7.856 26.447-186.346 1.00 32.29 N ATOM 991 CA THR A 103 6.940 25.581-187.061 1.00 31.77 C ATOM 992 C THR A 103 7.793 25.026-188.196 1.00 32.08 C ATOM 993 O THR A 103 8.020 25.714-189.188 1.00 33.09 O ATOM 994 CB THR A 103 5.763 26.372-187.664 1.00 27.57 C ATOM 995 OG1 THR A 103 4.982 26.950-186.615 1.00 27.15 O ATOM 996 CG2 THR A 103 4.872 25.460-188.495 1.00 27.67 C ATOM 997 N VAL A 104 8.291 23.801-188.039 1.00 25.88 N ATOM 998 CA VAL A 104 9.118 23.175-189.076 1.00 25.27 C ATOM 999 C VAL A 104 8.626 21.764-189.429 1.00 24.93 C ATOM 1000 O VAL A 104 7.986 21.094-188.617 1.00 23.86 O ATOM 1001 CB VAL A 104 10.593 23.085-188.637 1.00 32.75 C ATOM 1002 CG1 VAL A 104 11.155 24.480-188.419 1.00 31.37 C ATOM 1003 CG2 VAL A 104 10.704 22.248-187.364 1.00 29.20 C ATOM 1004 N LYS A 105 8.927 21.323-190.646 1.00 26.93 N ATOM 1005 CA LYS A 105 8.506 20.003-191.109 1.00 25.41 C ATOM 1006 C LYS A 105 9.652 18.997-191.206 1.00 24.99 C ATOM 1007 O LYS A 105 9.431 17.830-191.542 1.00 23.00 O ATOM 1008 CB LYS A 105 7.837 20.109-192.485 1.00 37.70 C ATOM 1009 CG LYS A 105 6.537 20.892-192.532 1.00 40.27 C ATOM 1010 CD LYS A 105 5.989 20.890-193.950 1.00 41.04 C ATOM 1011 CE LYS A 105 4.690 21.656-194.053 1.00 43.87 C ATOM 1012 NZ LYS A 105 3.693 21.086-193.122 1.00 47.05 N ATOM 1013 N LYS A 106 10.867 19.437-190.904 1.00 23.23 N ATOM 1014 CA LYS A 106 12.023 18.553-191.001 1.00 22.97 C ATOM 1015 C LYS A 106 12.726 18.345-189.664 1.00 22.72 C ATOM 1016 O LYS A 106 12.874 19.281-188.877 1.00 21.66 O ATOM 1017 CB LYS A 106 13.022 19.120-192.020 1.00 29.99 C ATOM 1018 CG LYS A 106 14.252 18.259-192.278 1.00 30.30 C ATOM 1019 CD LYS A 106 15.388 19.080-192.903 1.00 28.26 C ATOM 1020 CE LYS A 106 14.993 19.652-194.248 1.00 29.04 C ATOM 1021 NZ LYS A 106 16.073 20.460-194.887 1.00 27.35 N ATOM 1022 N ILE A 107 13.158 17.110-189.419 1.00 22.71 N ATOM 1023 CA ILE A 107 13.870 16.784-188.191 1.00 22.94 C ATOM 1024 C ILE A 107 15.298 16.350-188.454 1.00 23.35 C ATOM 1025 O ILE A 107 15.603 15.743-189.479 1.00 23.58 O ATOM 1026 CB ILE A 107 13.209 15.637-187.409 1.00 16.85 C ATOM 1027 CG1 ILE A 107 12.908 14.470-188.349 1.00 16.79 C ATOM 1028 CG2 ILE A 107 11.982 16.137-186.684 1.00 18.21 C ATOM 1029 CD1 ILE A 107 12.633 13.164-187.625 1.00 19.12 C ATOM 1030 N PHE A 108 16.169 16.676-187.507 1.00 28.54 N ATOM 1031 CA PHE A 108 17.569 16.296-187.557 1.00 28.55 C ATOM 1032 C PHE A 108 17.654 15.031-186.700 1.00 27.95 C ATOM 1033 O PHE A 108 17.227 15.032-185.546 1.00 27.19 O ATOM 1034 CB PHE A 108 18.434 17.397-186.944 1.00 25.33 C ATOM 1035 CG PHE A 108 19.855 16.982-186.675 1.00 25.01 C ATOM 1036 CD1 PHE A 108 20.853 17.212-187.613 1.00 24.96 C ATOM 1037 CD2 PHE A 108 20.193 16.361-185.476 1.00 25.77 C ATOM 1038 CE1 PHE A 108 22.175 16.832-187.359 1.00 26.16 C ATOM 1039 CE2 PHE A 108 21.514 15.970-185.210 1.00 25.40 C ATOM 1040 CZ PHE A 108 22.505 16.207-186.148 1.00 26.29 C ATOM 1041 N VAL A 109 18.179 13.956-187.275 1.00 26.09 N ATOM 1042 CA VAL A 109 18.327 12.684-186.571 1.00 25.42 C ATOM 1043 C VAL A 109 19.826 12.421-186.443 1.00 26.14 C ATOM 1044 O VAL A 109 20.495 12.127-187.441 1.00 25.59 O ATOM 1045 CB VAL A 109 17.696 11.523-187.370 1.00 17.56 C ATOM 1046 CG1 VAL A 109 17.748 10.237-186.555 1.00 19.20 C ATOM 1047 CG2 VAL A 109 16.260 11.868-187.750 1.00 18.43 C ATOM 1048 N GLY A 110 20.353 12.535-185.223 1.00 22.15 N ATOM 1049 CA GLY A 110 21.772 12.331-185.018 1.00 22.99 C ATOM 1050 C GLY A 110 22.122 11.122-184.190 1.00 23.35 C ATOM 1051 O GLY A 110 21.383 10.743-183.278 1.00 24.36 O ATOM 1052 N GLY A 111 23.265 10.525-184.508 1.00 28.53 N ATOM 1053 CA GLY A 111 23.715 9.344-183.796 1.00 29.06 C ATOM 1054 C GLY A 111 23.314 8.040-184.468 1.00 30.62 C ATOM 1055 O GLY A 111 23.222 7.013-183.799 1.00 31.42 O ATOM 1056 N ILE A 112 23.082 8.059-185.780 1.00 22.43 N ATOM 1057 CA ILE A 112 22.695 6.835-186.480 1.00 23.87 C ATOM 1058 C ILE A 112 23.894 6.003-186.949 1.00 24.00 C ATOM 1059 O ILE A 112 24.888 6.550-187.438 1.00 22.45 O ATOM 1060 CB ILE A 112 21.761 7.139-187.702 1.00 22.54 C ATOM 1061 CG1 ILE A 112 22.441 8.092-188.689 1.00 23.39 C ATOM 1062 CG2 ILE A 112 20.450 7.726-187.213 1.00 24.23 C ATOM 1063 CD1 ILE A 112 21.600 8.412-189.911 1.00 23.65 C ATOM 1064 N LYS A 113 23.798 4.684-186.773 1.00 25.71 N ATOM 1065 CA LYS A 113 24.855 3.748-187.176 1.00 29.11 C ATOM 1066 C LYS A 113 25.205 3.946-188.637 1.00 29.97 C ATOM 1067 O LYS A 113 24.333 4.233-189.455 1.00 31.10 O ATOM 1068 CB LYS A 113 24.411 2.293-186.961 1.00 31.41 C ATOM 1069 CG LYS A 113 24.546 1.798-185.541 1.00 35.79 C ATOM 1070 CD LYS A 113 23.767 0.513-185.314 1.00 38.09 C ATOM 1071 CE LYS A 113 24.283 -0.635-186.165 1.00 40.43 C ATOM 1072 NZ LYS A 113 23.417 -1.843-186.007 1.00 42.07 N ATOM 1073 N GLU A 114 26.480 3.773-188.967 1.00 34.82 N ATOM 1074 CA GLU A 114 26.944 3.971-190.337 1.00 37.36 C ATOM 1075 C GLU A 114 26.195 3.118-191.351 1.00 35.93 C ATOM 1076 O GLU A 114 26.018 3.527-192.500 1.00 37.23 O ATOM 1077 CB GLU A 114 28.446 3.691-190.441 1.00 79.05 C ATOM 1078 CG GLU A 114 28.821 2.224-190.415 1.00 85.13 C ATOM 1079 CD GLU A 114 30.302 2.018-190.640 1.00 87.13 C ATOM 1080 OE1 GLU A 114 30.841 2.642-191.578 1.00 87.17 O ATOM 1081 OE2 GLU A 114 30.926 1.234-189.890 1.00 88.71 O ATOM 1082 N ASP A 115 25.741 1.943-190.925 1.00 41.61 N ATOM 1083 CA ASP A 115 25.017 1.048-191.817 1.00 41.48 C ATOM 1084 C ASP A 115 23.516 1.366-191.871 1.00 40.20 C ATOM 1085 O ASP A 115 22.711 0.547-192.332 1.00 38.32 O ATOM 1086 CB ASP A 115 25.223 -0.400-191.377 1.00 44.31 C ATOM 1087 CG ASP A 115 24.356 -0.777-190.202 1.00 45.42 C ATOM 1088 OD1 ASP A 115 24.296 -0.008-189.223 1.00 47.94 O ATOM 1089 OD2 ASP A 115 23.733 -1.853-190.253 1.00 44.73 O ATOM 1090 N THR A 116 23.135 2.552-191.404 1.00 34.53 N ATOM 1091 CA THR A 116 21.730 2.927-191.426 1.00 33.39 C ATOM 1092 C THR A 116 21.279 3.212-192.849 1.00 33.49 C ATOM 1093 O THR A 116 21.955 3.913-193.610 1.00 33.20 O ATOM 1094 CB THR A 116 21.446 4.169-190.560 1.00 29.58 C ATOM 1095 OG1 THR A 116 21.734 3.866-189.194 1.00 29.72 O ATOM 1096 CG2 THR A 116 19.985 4.576-190.668 1.00 29.87 C ATOM 1097 N GLU A 117 20.131 2.647-193.196 1.00 33.72 N ATOM 1098 CA GLU A 117 19.548 2.828-194.508 1.00 34.91 C ATOM 1099 C GLU A 117 18.163 3.446-194.326 1.00 34.13 C ATOM 1100 O GLU A 117 17.583 3.384-193.235 1.00 33.38 O ATOM 1101 CB GLU A 117 19.477 1.481-195.234 1.00 38.84 C ATOM 1102 CG GLU A 117 20.831 1.002-195.767 1.00 44.52 C ATOM 1103 CD GLU A 117 20.854 -0.487-196.096 1.00 48.66 C ATOM 1104 OE1 GLU A 117 19.888 -0.981-196.715 1.00 52.12 O ATOM 1105 OE2 GLU A 117 21.843 -1.166-195.743 1.00 49.84 O ATOM 1106 N GLU A 118 17.637 4.043-195.392 1.00 40.82 N ATOM 1107 CA GLU A 118 16.347 4.711-195.327 1.00 40.28 C ATOM 1108 C GLU A 118 15.199 3.876-194.793 1.00 39.20 C ATOM 1109 O GLU A 118 14.352 4.389-194.057 1.00 37.94 O ATOM 1110 CB GLU A 118 15.986 5.274-196.694 1.00 57.83 C ATOM 1111 CG GLU A 118 17.111 6.074-197.295 1.00 58.48 C ATOM 1112 CD GLU A 118 16.619 7.222-198.133 1.00 60.86 C ATOM 1113 OE1 GLU A 118 15.724 7.001-198.979 1.00 60.36 O ATOM 1114 OE2 GLU A 118 17.135 8.346-197.945 1.00 61.21 O ATOM 1115 N HIS A 119 15.150 2.596-195.143 1.00 24.31 N ATOM 1116 CA HIS A 119 14.051 1.785-194.637 1.00 25.61 C ATOM 1117 C HIS A 119 14.072 1.811-193.103 1.00 24.73 C ATOM 1118 O HIS A 119 13.023 1.736-192.462 1.00 24.00 O ATOM 1119 CB HIS A 119 14.128 0.339-195.153 1.00 39.37 C ATOM 1120 CG HIS A 119 15.316 -0.424-194.659 1.00 39.43 C ATOM 1121 ND1 HIS A 119 16.561 -0.325-195.245 1.00 42.58 N ATOM 1122 CD2 HIS A 119 15.453 -1.282-193.620 1.00 37.01 C ATOM 1123 CE1 HIS A 119 17.415 -1.089-194.586 1.00 37.68 C ATOM 1124 NE2 HIS A 119 16.768 -1.680-193.595 1.00 40.90 N ATOM 1125 N HIS A 120 15.262 1.939-192.521 1.00 26.71 N ATOM 1126 CA HIS A 120 15.386 1.975-191.062 1.00 28.55 C ATOM 1127 C HIS A 120 14.643 3.168-190.511 1.00 28.08 C ATOM 1128 O HIS A 120 13.906 3.059-189.533 1.00 27.34 O ATOM 1129 CB HIS A 120 16.846 2.093-190.625 1.00 27.88 C ATOM 1130 CG HIS A 120 17.680 0.889-190.931 1.00 29.85 C ATOM 1131 ND1 HIS A 120 17.357 -0.373-190.485 1.00 32.20 N ATOM 1132 CD2 HIS A 120 18.858 0.768-191.586 1.00 30.74 C ATOM 1133 CE1 HIS A 120 18.303 -1.220-190.848 1.00 29.16 C ATOM 1134 NE2 HIS A 120 19.225 -0.553-191.517 1.00 31.77 N ATOM 1135 N LEU A 121 14.862 4.319-191.138 1.00 26.93 N ATOM 1136 CA LEU A 121 14.222 5.553-190.714 1.00 27.39 C ATOM 1137 C LEU A 121 12.709 5.503-190.889 1.00 26.39 C ATOM 1138 O LEU A 121 11.959 5.990-190.035 1.00 28.67 O ATOM 1139 CB LEU A 121 14.826 6.727-191.482 1.00 29.34 C ATOM 1140 CG LEU A 121 16.274 6.974-191.046 1.00 32.18 C ATOM 1141 CD1 LEU A 121 16.988 7.913-192.004 1.00 32.71 C ATOM 1142 CD2 LEU A 121 16.266 7.539-189.639 1.00 32.49 C ATOM 1143 N ARG A 122 12.262 4.897-191.983 1.00 28.53 N ATOM 1144 CA ARG A 122 10.833 4.792-192.256 1.00 26.83 C ATOM 1145 C ARG A 122 10.139 3.931-191.231 1.00 27.59 C ATOM 1146 O ARG A 122 9.051 4.264-190.766 1.00 26.65 O ATOM 1147 CB ARG A 122 10.582 4.188-193.645 1.00 24.28 C ATOM 1148 CG ARG A 122 10.742 5.149-194.778 1.00 24.33 C ATOM 1149 CD ARG A 122 10.349 4.491-196.097 1.00 25.98 C ATOM 1150 NE ARG A 122 10.463 5.445-197.187 1.00 26.03 N ATOM 1151 CZ ARG A 122 9.617 6.444-197.394 1.00 28.10 C ATOM 1152 NH1 ARG A 122 8.582 6.624-196.589 1.00 26.41 N ATOM 1153 NH2 ARG A 122 9.815 7.274-198.403 1.00 28.95 N ATOM 1154 N ASP A 123 10.771 2.811-190.892 1.00 31.62 N ATOM 1155 CA ASP A 123 10.209 1.877-189.930 1.00 32.48 C ATOM 1156 C ASP A 123 9.912 2.504-188.578 1.00 32.99 C ATOM 1157 O ASP A 123 9.010 2.059-187.869 1.00 32.91 O ATOM 1158 CB ASP A 123 11.140 0.675-189.765 1.00 37.90 C ATOM 1159 CG ASP A 123 10.825 -0.441-190.747 1.00 40.35 C ATOM 1160 OD1 ASP A 123 10.141 -0.178-191.762 1.00 42.11 O ATOM 1161 OD2 ASP A 123 11.265 -1.582-190.507 1.00 41.82 O ATOM 1162 N TYR A 124 10.663 3.536-188.215 1.00 23.18 N ATOM 1163 CA TYR A 124 10.424 4.192-186.936 1.00 23.40 C ATOM 1164 C TYR A 124 9.570 5.441-187.073 1.00 24.42 C ATOM 1165 O TYR A 124 8.634 5.650-186.308 1.00 23.75 O ATOM 1166 CB TYR A 124 11.739 4.596-186.259 1.00 19.57 C ATOM 1167 CG TYR A 124 11.493 5.350-184.968 1.00 19.16 C ATOM 1168 CD1 TYR A 124 10.909 4.705-183.871 1.00 20.23 C ATOM 1169 CD2 TYR A 124 11.725 6.726-184.879 1.00 20.90 C ATOM 1170 CE1 TYR A 124 10.552 5.406-182.734 1.00 22.67 C ATOM 1171 CE2 TYR A 124 11.370 7.443-183.732 1.00 22.80 C ATOM 1172 CZ TYR A 124 10.777 6.769-182.665 1.00 22.56 C ATOM 1173 OH TYR A 124 10.376 7.446-181.539 1.00 24.20 O ATOM 1174 N PHE A 125 9.889 6.265-188.062 1.00 25.56 N ATOM 1175 CA PHE A 125 9.185 7.526-188.236 1.00 26.78 C ATOM 1176 C PHE A 125 7.833 7.567-188.933 1.00 25.94 C ATOM 1177 O PHE A 125 7.040 8.461-188.653 1.00 26.18 O ATOM 1178 CB PHE A 125 10.125 8.532-188.900 1.00 18.96 C ATOM 1179 CG PHE A 125 11.213 9.022-187.992 1.00 18.46 C ATOM 1180 CD1 PHE A 125 10.899 9.746-186.835 1.00 20.20 C ATOM 1181 CD2 PHE A 125 12.553 8.757-188.278 1.00 19.16 C ATOM 1182 CE1 PHE A 125 11.909 10.203-185.970 1.00 17.49 C ATOM 1183 CE2 PHE A 125 13.579 9.207-187.417 1.00 18.65 C ATOM 1184 CZ PHE A 125 13.257 9.930-186.265 1.00 20.07 C ATOM 1185 N GLU A 126 7.549 6.627-189.825 1.00 29.33 N ATOM 1186 CA GLU A 126 6.270 6.670-190.517 1.00 30.91 C ATOM 1187 C GLU A 126 5.067 6.702-189.581 1.00 31.69 C ATOM 1188 O GLU A 126 4.034 7.279-189.911 1.00 29.86 O ATOM 1189 CB GLU A 126 6.144 5.502-191.500 1.00 22.64 C ATOM 1190 CG GLU A 126 6.813 5.777-192.838 1.00 21.64 C ATOM 1191 CD GLU A 126 6.495 4.723-193.883 1.00 23.75 C ATOM 1192 OE1 GLU A 126 5.623 3.870-193.609 1.00 21.50 O ATOM 1193 OE2 GLU A 126 7.108 4.753-194.976 1.00 23.10 O ATOM 1194 N GLN A 127 5.204 6.096-188.408 1.00 25.67 N ATOM 1195 CA GLN A 127 4.110 6.068-187.440 1.00 29.16 C ATOM 1196 C GLN A 127 3.706 7.471-186.986 1.00 29.56 C ATOM 1197 O GLN A 127 2.632 7.650-186.410 1.00 29.54 O ATOM 1198 CB GLN A 127 4.519 5.247-186.217 1.00 35.84 C ATOM 1199 CG GLN A 127 5.747 5.805-185.509 1.00 43.47 C ATOM 1200 CD GLN A 127 6.136 5.009-184.281 1.00 47.12 C ATOM 1201 OE1 GLN A 127 5.382 4.940-183.305 1.00 47.74 O ATOM 1202 NE2 GLN A 127 7.320 4.399-184.321 1.00 49.61 N ATOM 1203 N TYR A 128 4.557 8.463-187.252 1.00 24.40 N ATOM 1204 CA TYR A 128 4.281 9.837-186.840 1.00 25.22 C ATOM 1205 C TYR A 128 3.643 10.709-187.901 1.00 26.04 C ATOM 1206 O TYR A 128 3.150 11.792-187.587 1.00 26.86 O ATOM 1207 CB TYR A 128 5.557 10.525-186.350 1.00 26.06 C ATOM 1208 CG TYR A 128 6.127 9.929-185.091 1.00 27.14 C ATOM 1209 CD1 TYR A 128 7.074 8.908-185.144 1.00 26.02 C ATOM 1210 CD2 TYR A 128 5.712 10.381-183.833 1.00 28.29 C ATOM 1211 CE1 TYR A 128 7.596 8.355-183.987 1.00 27.93 C ATOM 1212 CE2 TYR A 128 6.226 9.832-182.669 1.00 28.70 C ATOM 1213 CZ TYR A 128 7.166 8.823-182.750 1.00 28.10 C ATOM 1214 OH TYR A 128 7.681 8.283-181.596 1.00 28.72 O ATOM 1215 N GLY A 129 3.653 10.254-189.152 1.00 26.04 N ATOM 1216 CA GLY A 129 3.060 11.044-190.222 1.00 26.53 C ATOM 1217 C GLY A 129 3.668 10.766-191.590 1.00 26.57 C ATOM 1218 O GLY A 129 4.683 10.065-191.701 1.00 26.04 O ATOM 1219 N LYS A 130 3.052 11.314-192.634 1.00 23.22 N ATOM 1220 CA LYS A 130 3.532 11.123-193.999 1.00 22.52 C ATOM 1221 C LYS A 130 4.943 11.659-194.157 1.00 21.71 C ATOM 1222 O LYS A 130 5.193 12.823-193.879 1.00 20.14 O ATOM 1223 CB LYS A 130 2.609 11.839-194.997 1.00 43.42 C ATOM 1224 CG LYS A 130 3.117 11.862-196.445 1.00 45.80 C ATOM 1225 CD LYS A 130 3.271 10.453-197.014 1.00 45.01 C ATOM 1226 CE LYS A 130 3.755 10.461-198.468 1.00 48.61 C ATOM 1227 NZ LYS A 130 2.765 11.067-199.406 1.00 47.10 N ATOM 1228 N ILE A 131 5.866 10.814-194.597 1.00 31.87 N ATOM 1229 CA ILE A 131 7.239 11.260-194.802 1.00 29.95 C ATOM 1230 C ILE A 131 7.349 11.750-196.237 1.00 31.16 C ATOM 1231 O ILE A 131 6.893 11.080-197.171 1.00 29.48 O ATOM 1232 CB ILE A 131 8.264 10.118-194.571 1.00 22.14 C ATOM 1233 CG1 ILE A 131 8.211 9.651-193.109 1.00 22.05 C ATOM 1234 CG2 ILE A 131 9.661 10.598-194.933 1.00 19.83 C ATOM 1235 CD1 ILE A 131 9.157 8.511-192.768 1.00 22.08 C ATOM 1236 N GLU A 132 7.939 12.929-196.405 1.00 28.15 N ATOM 1237 CA GLU A 132 8.110 13.519-197.724 1.00 30.98 C ATOM 1238 C GLU A 132 9.514 13.288-198.265 1.00 30.97 C ATOM 1239 O GLU A 132 9.673 12.927-199.430 1.00 30.08 O ATOM 1240 CB GLU A 132 7.830 15.022-197.684 1.00 38.59 C ATOM 1241 CG GLU A 132 6.352 15.405-197.596 1.00 42.18 C ATOM 1242 CD GLU A 132 5.526 14.872-198.767 1.00 44.65 C ATOM 1243 OE1 GLU A 132 6.064 14.791-199.894 1.00 46.90 O ATOM 1244 OE2 GLU A 132 4.334 14.550-198.563 1.00 46.91 O ATOM 1245 N VAL A 133 10.526 13.482-197.420 1.00 31.73 N ATOM 1246 CA VAL A 133 11.916 13.309-197.841 1.00 32.55 C ATOM 1247 C VAL A 133 12.811 12.739-196.744 1.00 32.05 C ATOM 1248 O VAL A 133 12.691 13.106-195.580 1.00 31.52 O ATOM 1249 CB VAL A 133 12.540 14.652-198.279 1.00 32.23 C ATOM 1250 CG1 VAL A 133 13.888 14.402-198.932 1.00 35.40 C ATOM 1251 CG2 VAL A 133 11.596 15.394-199.216 1.00 35.31 C ATOM 1252 N ILE A 134 13.713 11.847-197.136 1.00 26.65 N ATOM 1253 CA ILE A 134 14.659 11.226-196.220 1.00 27.57 C ATOM 1254 C ILE A 134 16.051 11.441-196.805 1.00 29.58 C ATOM 1255 O ILE A 134 16.306 11.134-197.974 1.00 27.01 O ATOM 1256 CB ILE A 134 14.380 9.712-196.056 1.00 25.49 C ATOM 1257 CG1 ILE A 134 13.038 9.516-195.350 1.00 27.80 C ATOM 1258 CG2 ILE A 134 15.486 9.051-195.249 1.00 24.45 C ATOM 1259 CD1 ILE A 134 12.635 8.067-195.155 1.00 27.66 C ATOM 1260 N GLU A 135 16.951 11.982-195.996 1.00 24.83 N ATOM 1261 CA GLU A 135 18.303 12.256-196.463 1.00 28.08 C ATOM 1262 C GLU A 135 19.364 11.782-195.485 1.00 27.41 C ATOM 1263 O GLU A 135 19.572 12.415-194.447 1.00 24.33 O ATOM 1264 CB GLU A 135 18.499 13.758-196.663 1.00 45.25 C ATOM 1265 CG GLU A 135 17.523 14.426-197.602 1.00 51.71 C ATOM 1266 CD GLU A 135 17.574 15.944-197.491 1.00 55.63 C ATOM 1267 OE1 GLU A 135 17.144 16.487-196.447 1.00 56.32 O ATOM 1268 OE2 GLU A 135 18.055 16.594-198.444 1.00 56.60 O ATOM 1269 N ILE A 136 20.035 10.681-195.805 1.00 24.09 N ATOM 1270 CA ILE A 136 21.108 10.198-194.943 1.00 23.86 C ATOM 1271 C ILE A 136 22.379 10.914-195.396 1.00 23.04 C ATOM 1272 O ILE A 136 22.861 10.713-196.511 1.00 22.44 O ATOM 1273 CB ILE A 136 21.284 8.684-195.052 1.00 28.46 C ATOM 1274 CG1 ILE A 136 19.998 7.993-194.604 1.00 29.91 C ATOM 1275 CG2 ILE A 136 22.455 8.253-194.202 1.00 27.92 C ATOM 1276 CD1 ILE A 136 20.118 6.501-194.438 1.00 32.25 C ATOM 1277 N MET A 137 22.919 11.752-194.517 1.00 25.58 N ATOM 1278 CA MET A 137 24.086 12.557-194.843 1.00 29.09 C ATOM 1279 C MET A 137 25.434 11.871-194.937 1.00 30.14 C ATOM 1280 O MET A 137 25.786 10.994-194.146 1.00 29.46 O ATOM 1281 CB MET A 137 24.173 13.746-193.882 1.00 29.05 C ATOM 1282 CG MET A 137 22.876 14.549-193.806 1.00 28.79 C ATOM 1283 SD MET A 137 22.179 14.979-195.430 1.00 30.98 S ATOM 1284 CE MET A 137 23.232 16.298-195.881 1.00 30.15 C ATOM 1285 N THR A 138 26.187 12.301-195.939 1.00 34.69 N ATOM 1286 CA THR A 138 27.515 11.781-196.204 1.00 36.98 C ATOM 1287 C THR A 138 28.386 12.942-196.624 1.00 37.82 C ATOM 1288 O THR A 138 27.895 13.999-197.008 1.00 37.00 O ATOM 1289 CB THR A 138 27.507 10.787-197.363 1.00 27.85 C ATOM 1290 OG1 THR A 138 26.949 11.424-198.523 1.00 28.83 O ATOM 1291 CG2 THR A 138 26.697 9.564-197.005 1.00 26.77 C ATOM 1292 N ASP A 139 29.689 12.742-196.557 1.00 28.56 N ATOM 1293 CA ASP A 139 30.601 13.785-196.964 1.00 30.47 C ATOM 1294 C ASP A 139 30.616 13.814-198.489 1.00 31.54 C ATOM 1295 O ASP A 139 30.892 12.802-199.134 1.00 31.57 O ATOM 1296 CB ASP A 139 31.996 13.499-196.412 1.00 44.26 C ATOM 1297 CG ASP A 139 32.977 14.583-196.750 1.00 46.06 C ATOM 1298 OD1 ASP A 139 33.806 14.368-197.660 1.00 46.10 O ATOM 1299 OD2 ASP A 139 32.906 15.655-196.111 1.00 45.59 O ATOM 1300 N ARG A 140 30.284 14.964-199.059 1.00 78.06 N ATOM 1301 CA ARG A 140 30.275 15.107-200.506 1.00 79.28 C ATOM 1302 C ARG A 140 31.716 15.274-200.964 1.00 79.85 C ATOM 1303 O ARG A 140 32.144 16.371-201.314 1.00 81.19 O ATOM 1304 CB ARG A 140 29.452 16.329-200.918 1.00142.44 C ATOM 1305 CG ARG A 140 28.003 16.295-200.457 1.00144.15 C ATOM 1306 CD ARG A 140 27.245 17.530-200.930 1.00144.53 C ATOM 1307 NE ARG A 140 27.155 17.600-202.387 1.00146.78 N ATOM 1308 CZ ARG A 140 26.594 18.603-203.056 1.00147.51 C ATOM 1309 NH1 ARG A 140 26.072 19.631-202.401 1.00148.61 N ATOM 1310 NH2 ARG A 140 26.554 18.579-204.383 1.00149.69 N ATOM 1311 N GLY A 141 32.464 14.178-200.944 1.00 40.02 N ATOM 1312 CA GLY A 141 33.854 14.217-201.351 1.00 38.87 C ATOM 1313 C GLY A 141 34.463 12.856-201.122 1.00 37.75 C ATOM 1314 O GLY A 141 34.996 12.238-202.042 1.00 38.81 O ATOM 1315 N SER A 142 34.381 12.387-199.882 1.00 31.40 N ATOM 1316 CA SER A 142 34.904 11.080-199.519 1.00 28.96 C ATOM 1317 C SER A 142 33.772 10.062-199.591 1.00 27.99 C ATOM 1318 O SER A 142 34.001 8.858-199.740 1.00 27.15 O ATOM 1319 CB SER A 142 35.466 11.113-198.099 1.00 35.16 C ATOM 1320 OG SER A 142 34.445 11.389-197.150 1.00 31.91 O ATOM 1321 N GLY A 143 32.546 10.559-199.484 1.00 30.53 N ATOM 1322 CA GLY A 143 31.392 9.682-199.518 1.00 31.18 C ATOM 1323 C GLY A 143 31.216 8.973-198.187 1.00 31.27 C ATOM 1324 O GLY A 143 30.379 8.088-198.050 1.00 32.80 O ATOM 1325 N LYS A 144 32.015 9.357-197.200 1.00 36.47 N ATOM 1326 CA LYS A 144 31.931 8.751-195.875 1.00 35.79 C ATOM 1327 C LYS A 144 30.627 9.158-195.185 1.00 35.37 C ATOM 1328 O LYS A 144 30.210 10.312-195.268 1.00 33.23 O ATOM 1329 CB LYS A 144 33.116 9.205-195.020 1.00 85.32 C ATOM 1330 CG LYS A 144 34.480 8.877-195.607 1.00 87.46 C ATOM 1331 CD LYS A 144 34.850 7.416-195.411 1.00 89.98 C ATOM 1332 CE LYS A 144 35.113 7.109-193.945 1.00 90.20 C ATOM 1333 NZ LYS A 144 35.546 5.701-193.747 1.00 90.03 N ATOM 1334 N LYS A 145 29.982 8.209-194.514 1.00 31.37 N ATOM 1335 CA LYS A 145 28.744 8.498-193.784 1.00 31.66 C ATOM 1336 C LYS A 145 29.082 9.459-192.644 1.00 30.73 C ATOM 1337 O LYS A 145 30.103 9.300-191.992 1.00 30.21 O ATOM 1338 CB LYS A 145 28.161 7.210-193.196 1.00 63.22 C ATOM 1339 CG LYS A 145 27.479 6.294-194.198 1.00 64.54 C ATOM 1340 CD LYS A 145 26.178 6.899-194.701 1.00 66.80 C ATOM 1341 CE LYS A 145 25.262 5.835-195.294 1.00 68.63 C ATOM 1342 NZ LYS A 145 25.894 5.135-196.444 1.00 70.11 N ATOM 1343 N ARG A 146 28.235 10.452-192.397 1.00 33.94 N ATOM 1344 CA ARG A 146 28.509 11.403-191.323 1.00 32.30 C ATOM 1345 C ARG A 146 27.789 11.101-190.010 1.00 32.56 C ATOM 1346 O ARG A 146 27.988 11.803-189.014 1.00 29.21 O ATOM 1347 CB ARG A 146 28.185 12.824-191.777 1.00 27.64 C ATOM 1348 CG ARG A 146 29.027 13.283-192.967 1.00 27.99 C ATOM 1349 CD ARG A 146 28.845 14.757-193.215 1.00 28.36 C ATOM 1350 NE ARG A 146 29.202 15.523-192.027 1.00 28.15 N ATOM 1351 CZ ARG A 146 28.945 16.815-191.874 1.00 29.82 C ATOM 1352 NH1 ARG A 146 28.327 17.476-192.845 1.00 28.36 N ATOM 1353 NH2 ARG A 146 29.295 17.438-190.755 1.00 30.27 N ATOM 1354 N GLY A 147 26.961 10.060-190.008 1.00 25.82 N ATOM 1355 CA GLY A 147 26.253 9.683-188.798 1.00 26.12 C ATOM 1356 C GLY A 147 24.979 10.436-188.430 1.00 25.75 C ATOM 1357 O GLY A 147 24.594 10.452-187.261 1.00 24.45 O ATOM 1358 N PHE A 148 24.320 11.060-189.400 1.00 24.18 N ATOM 1359 CA PHE A 148 23.075 11.773-189.123 1.00 24.39 C ATOM 1360 C PHE A 148 22.230 11.923-190.376 1.00 24.91 C ATOM 1361 O PHE A 148 22.748 11.880-191.496 1.00 25.32 O ATOM 1362 CB PHE A 148 23.350 13.153-188.514 1.00 23.02 C ATOM 1363 CG PHE A 148 23.955 14.146-189.469 1.00 25.69 C ATOM 1364 CD1 PHE A 148 23.146 14.971-190.247 1.00 24.66 C ATOM 1365 CD2 PHE A 148 25.338 14.281-189.571 1.00 25.22 C ATOM 1366 CE1 PHE A 148 23.713 15.921-191.115 1.00 26.58 C ATOM 1367 CE2 PHE A 148 25.905 15.227-190.436 1.00 25.83 C ATOM 1368 CZ PHE A 148 25.089 16.045-191.206 1.00 26.00 C ATOM 1369 N ALA A 149 20.927 12.099-190.182 1.00 23.91 N ATOM 1370 CA ALA A 149 20.006 12.247-191.297 1.00 23.11 C ATOM 1371 C ALA A 149 18.994 13.360-191.076 1.00 23.79 C ATOM 1372 O ALA A 149 18.901 13.938-189.990 1.00 24.73 O ATOM 1373 CB ALA A 149 19.282 10.952-191.527 1.00 18.62 C ATOM 1374 N PHE A 150 18.246 13.653-192.132 1.00 23.62 N ATOM 1375 CA PHE A 150 17.199 14.656-192.107 1.00 24.88 C ATOM 1376 C PHE A 150 15.968 13.959-192.660 1.00 25.03 C ATOM 1377 O PHE A 150 16.045 13.267-193.679 1.00 21.68 O ATOM 1378 CB PHE A 150 17.549 15.840-193.007 1.00 24.06 C ATOM 1379 CG PHE A 150 18.530 16.792-192.399 1.00 25.90 C ATOM 1380 CD1 PHE A 150 18.186 17.546-191.272 1.00 26.46 C ATOM 1381 CD2 PHE A 150 19.803 16.948-192.951 1.00 28.30 C ATOM 1382 CE1 PHE A 150 19.087 18.441-190.703 1.00 26.27 C ATOM 1383 CE2 PHE A 150 20.714 17.843-192.387 1.00 28.98 C ATOM 1384 CZ PHE A 150 20.352 18.593-191.258 1.00 28.17 C ATOM 1385 N VAL A 151 14.842 14.119-191.976 1.00 23.39 N ATOM 1386 CA VAL A 151 13.591 13.511-192.409 1.00 24.67 C ATOM 1387 C VAL A 151 12.593 14.644-192.490 1.00 24.54 C ATOM 1388 O VAL A 151 12.449 15.416-191.538 1.00 24.38 O ATOM 1389 CB VAL A 151 13.105 12.462-191.390 1.00 18.52 C ATOM 1390 CG1 VAL A 151 11.769 11.871-191.828 1.00 18.77 C ATOM 1391 CG2 VAL A 151 14.148 11.384-191.241 1.00 19.16 C ATOM 1392 N THR A 152 11.926 14.768-193.630 1.00 21.52 N ATOM 1393 CA THR A 152 10.953 15.836-193.816 1.00 22.05 C ATOM 1394 C THR A 152 9.549 15.265-193.876 1.00 20.79 C ATOM 1395 O THR A 152 9.301 14.308-194.608 1.00 21.73 O ATOM 1396 CB THR A 152 11.237 16.625-195.119 1.00 23.57 C ATOM 1397 OG1 THR A 152 12.564 17.161-195.069 1.00 26.61 O ATOM 1398 CG2 THR A 152 10.260 17.773-195.281 1.00 25.24 C ATOM 1399 N PHE A 153 8.634 15.845-193.104 1.00 27.98 N ATOM 1400 CA PHE A 153 7.250 15.378-193.086 1.00 28.69 C ATOM 1401 C PHE A 153 6.319 16.352-193.785 1.00 30.74 C ATOM 1402 O PHE A 153 6.724 17.437-194.194 1.00 30.65 O ATOM 1403 CB PHE A 153 6.741 15.171-191.655 1.00 17.63 C ATOM 1404 CG PHE A 153 7.486 14.121-190.883 1.00 19.08 C ATOM 1405 CD1 PHE A 153 8.707 14.411-190.296 1.00 20.79 C ATOM 1406 CD2 PHE A 153 6.950 12.851-190.717 1.00 18.13 C ATOM 1407 CE1 PHE A 153 9.384 13.455-189.550 1.00 18.83 C ATOM 1408 CE2 PHE A 153 7.623 11.883-189.970 1.00 19.70 C ATOM 1409 CZ PHE A 153 8.840 12.186-189.387 1.00 19.71 C ATOM 1410 N ASP A 154 5.057 15.952-193.892 1.00 38.00 N ATOM 1411 CA ASP A 154 4.025 16.747-194.541 1.00 41.06 C ATOM 1412 C ASP A 154 3.373 17.714-193.560 1.00 42.02 C ATOM 1413 O ASP A 154 2.931 18.797-193.937 1.00 41.14 O ATOM 1414 CB ASP A 154 2.957 15.810-195.103 1.00 70.39 C ATOM 1415 CG ASP A 154 2.490 16.217-196.476 1.00 76.80 C ATOM 1416 OD1 ASP A 154 1.577 15.552-197.006 1.00 79.29 O ATOM 1417 OD2 ASP A 154 3.038 17.195-197.028 1.00 78.08 O ATOM 1418 N ASP A 155 3.333 17.315-192.296 1.00 23.78 N ATOM 1419 CA ASP A 155 2.699 18.093-191.233 1.00 23.76 C ATOM 1420 C ASP A 155 3.687 18.480-190.134 1.00 23.78 C ATOM 1421 O ASP A 155 4.408 17.629-189.627 1.00 23.37 O ATOM 1422 CB ASP A 155 1.600 17.233-190.616 1.00 33.60 C ATOM 1423 CG ASP A 155 0.614 18.026-189.793 1.00 34.41 C ATOM 1424 OD1 ASP A 155 0.975 19.092-189.240 1.00 32.70 O ATOM 1425 OD2 ASP A 155 -0.539 17.556-189.692 1.00 35.68 O ATOM 1426 N HIS A 156 3.696 19.748-189.733 1.00 24.65 N ATOM 1427 CA HIS A 156 4.602 20.191-188.674 1.00 23.60 C ATOM 1428 C HIS A 156 4.297 19.472-187.356 1.00 22.49 C ATOM 1429 O HIS A 156 5.172 19.336-186.497 1.00 21.88 O ATOM 1430 CB HIS A 156 4.474 21.704-188.457 1.00 31.60 C ATOM 1431 CG HIS A 156 3.200 22.111-187.779 1.00 32.43 C ATOM 1432 ND1 HIS A 156 2.976 21.907-186.434 1.00 33.75 N ATOM 1433 CD2 HIS A 156 2.066 22.668-188.269 1.00 32.77 C ATOM 1434 CE1 HIS A 156 1.759 22.319-186.124 1.00 34.27 C ATOM 1435 NE2 HIS A 156 1.185 22.784-187.219 1.00 35.25 N ATOM 1436 N ASP A 157 3.057 19.020-187.189 1.00 25.41 N ATOM 1437 CA ASP A 157 2.681 18.331-185.960 1.00 23.90 C ATOM 1438 C ASP A 157 3.394 16.979-185.816 1.00 22.79 C ATOM 1439 O ASP A 157 3.570 16.478-184.698 1.00 23.45 O ATOM 1440 CB ASP A 157 1.168 18.134-185.895 1.00 29.50 C ATOM 1441 CG ASP A 157 0.710 17.617-184.545 1.00 31.55 C ATOM 1442 OD1 ASP A 157 1.084 18.228-183.518 1.00 33.92 O ATOM 1443 OD2 ASP A 157 -0.024 16.609-184.508 1.00 27.46 O ATOM 1444 N SER A 158 3.793 16.384-186.942 1.00 22.75 N ATOM 1445 CA SER A 158 4.509 15.111-186.895 1.00 24.15 C ATOM 1446 C SER A 158 5.833 15.376-186.193 1.00 24.89 C ATOM 1447 O SER A 158 6.250 14.634-185.305 1.00 24.18 O ATOM 1448 CB SER A 158 4.756 14.587-188.310 1.00 23.99 C ATOM 1449 OG SER A 158 3.527 14.230-188.906 1.00 25.43 O ATOM 1450 N VAL A 159 6.484 16.454-186.602 1.00 20.79 N ATOM 1451 CA VAL A 159 7.748 16.861-186.010 1.00 21.92 C ATOM 1452 C VAL A 159 7.559 17.185-184.532 1.00 21.97 C ATOM 1453 O VAL A 159 8.369 16.785-183.687 1.00 21.48 O ATOM 1454 CB VAL A 159 8.315 18.102-186.728 1.00 26.28 C ATOM 1455 CG1 VAL A 159 9.572 18.601-186.014 1.00 27.87 C ATOM 1456 CG2 VAL A 159 8.634 17.746-188.181 1.00 29.21 C ATOM 1457 N ASP A 160 6.492 17.908-184.213 1.00 25.07 N ATOM 1458 CA ASP A 160 6.235 18.259-182.821 1.00 26.09 C ATOM 1459 C ASP A 160 5.971 17.008-181.962 1.00 26.33 C ATOM 1460 O ASP A 160 6.524 16.884-180.869 1.00 24.76 O ATOM 1461 CB ASP A 160 5.069 19.255-182.728 1.00 21.34 C ATOM 1462 CG ASP A 160 5.370 20.577-183.441 1.00 23.11 C ATOM 1463 OD1 ASP A 160 6.556 20.965-183.498 1.00 21.96 O ATOM 1464 OD2 ASP A 160 4.422 21.235-183.934 1.00 24.18 O ATOM 1465 N LYS A 161 5.156 16.079-182.464 1.00 29.08 N ATOM 1466 CA LYS A 161 4.851 14.839-181.734 1.00 30.14 C ATOM 1467 C LYS A 161 6.117 14.041-181.473 1.00 30.35 C ATOM 1468 O LYS A 161 6.213 13.298-180.493 1.00 26.57 O ATOM 1469 CB LYS A 161 3.911 13.930-182.530 1.00 34.08 C ATOM 1470 CG LYS A 161 2.466 14.365-182.615 1.00 36.66 C ATOM 1471 CD LYS A 161 1.613 13.275-183.264 1.00 38.86 C ATOM 1472 CE LYS A 161 2.096 12.954-184.674 1.00 40.23 C ATOM 1473 NZ LYS A 161 1.201 12.000-185.373 1.00 41.88 N ATOM 1474 N ILE A 162 7.079 14.182-182.376 1.00 23.95 N ATOM 1475 CA ILE A 162 8.329 13.462-182.258 1.00 23.36 C ATOM 1476 C ILE A 162 9.298 14.093-181.281 1.00 24.91 C ATOM 1477 O ILE A 162 9.729 13.441-180.337 1.00 25.16 O ATOM 1478 CB ILE A 162 9.028 13.333-183.629 1.00 15.09 C ATOM 1479 CG1 ILE A 162 8.196 12.428-184.546 1.00 16.06 C ATOM 1480 CG2 ILE A 162 10.433 12.796-183.436 1.00 12.53 C ATOM 1481 CD1 ILE A 162 8.732 12.307-185.949 1.00 17.73 C ATOM 1482 N VAL A 163 9.619 15.365-181.487 1.00 22.23 N ATOM 1483 CA VAL A 163 10.595 16.032-180.640 1.00 22.03 C ATOM 1484 C VAL A 163 10.236 16.186-179.173 1.00 23.99 C ATOM 1485 O VAL A 163 11.118 16.446-178.356 1.00 25.05 O ATOM 1486 CB VAL A 163 10.998 17.408-181.224 1.00 26.78 C ATOM 1487 CG1 VAL A 163 11.449 17.227-182.681 1.00 26.68 C ATOM 1488 CG2 VAL A 163 9.845 18.391-181.127 1.00 27.74 C ATOM 1489 N ILE A 164 8.965 16.022-178.819 1.00 21.34 N ATOM 1490 CA ILE A 164 8.588 16.128-177.416 1.00 23.47 C ATOM 1491 C ILE A 164 8.905 14.818-176.688 1.00 23.66 C ATOM 1492 O ILE A 164 8.968 14.791-175.460 1.00 23.60 O ATOM 1493 CB ILE A 164 7.089 16.471-177.229 1.00 19.59 C ATOM 1494 CG1 ILE A 164 6.211 15.481-177.995 1.00 18.58 C ATOM 1495 CG2 ILE A 164 6.830 17.897-177.656 1.00 20.98 C ATOM 1496 CD1 ILE A 164 4.714 15.758-177.852 1.00 22.70 C ATOM 1497 N GLN A 165 9.107 13.738-177.447 1.00 23.89 N ATOM 1498 CA GLN A 165 9.452 12.439-176.859 1.00 24.92 C ATOM 1499 C GLN A 165 10.951 12.467-176.577 1.00 24.01 C ATOM 1500 O GLN A 165 11.685 13.230-177.202 1.00 25.84 O ATOM 1501 CB GLN A 165 9.132 11.298-177.830 1.00 43.27 C ATOM 1502 CG GLN A 165 7.656 11.145-178.165 1.00 48.13 C ATOM 1503 CD GLN A 165 6.843 10.587-177.010 1.00 53.18 C ATOM 1504 OE1 GLN A 165 5.611 10.668-177.008 1.00 53.60 O ATOM 1505 NE2 GLN A 165 7.527 10.008-176.025 1.00 55.55 N ATOM 1506 N LYS A 166 11.409 11.637-175.646 1.00 25.42 N ATOM 1507 CA LYS A 166 12.824 11.615-175.294 1.00 24.34 C ATOM 1508 C LYS A 166 13.662 10.617-176.085 1.00 23.08 C ATOM 1509 O LYS A 166 14.780 10.929-176.475 1.00 23.11 O ATOM 1510 CB LYS A 166 12.971 11.322-173.803 1.00 30.88 C ATOM 1511 CG LYS A 166 14.383 11.385-173.266 1.00 30.25 C ATOM 1512 CD LYS A 166 14.359 11.304-171.750 1.00 32.43 C ATOM 1513 CE LYS A 166 15.745 11.462-171.151 1.00 32.91 C ATOM 1514 NZ LYS A 166 16.350 12.757-171.520 1.00 35.50 N ATOM 1515 N TYR A 167 13.124 9.424-176.325 1.00 17.34 N ATOM 1516 CA TYR A 167 13.869 8.382-177.028 1.00 18.41 C ATOM 1517 C TYR A 167 13.271 7.972-178.365 1.00 18.72 C ATOM 1518 O TYR A 167 12.050 7.957-178.539 1.00 19.45 O ATOM 1519 CB TYR A 167 14.002 7.146-176.127 1.00 20.66 C ATOM 1520 CG TYR A 167 14.677 7.447-174.807 1.00 20.03 C ATOM 1521 CD1 TYR A 167 15.990 7.914-174.768 1.00 20.49 C ATOM 1522 CD2 TYR A 167 13.997 7.300-173.603 1.00 20.34 C ATOM 1523 CE1 TYR A 167 16.605 8.228-173.575 1.00 22.18 C ATOM 1524 CE2 TYR A 167 14.607 7.612-172.392 1.00 21.41 C ATOM 1525 CZ TYR A 167 15.912 8.075-172.385 1.00 21.03 C ATOM 1526 OH TYR A 167 16.541 8.370-171.199 1.00 21.94 O ATOM 1527 N HIS A 168 14.153 7.629-179.298 1.00 21.37 N ATOM 1528 CA HIS A 168 13.764 7.209-180.638 1.00 23.59 C ATOM 1529 C HIS A 168 14.739 6.134-181.067 1.00 23.44 C ATOM 1530 O HIS A 168 15.955 6.353-181.093 1.00 24.45 O ATOM 1531 CB HIS A 168 13.839 8.390-181.607 1.00 26.30 C ATOM 1532 CG HIS A 168 13.024 9.566-181.172 1.00 26.84 C ATOM 1533 ND1 HIS A 168 11.646 9.564-181.195 1.00 27.00 N ATOM 1534 CD2 HIS A 168 13.389 10.760-180.655 1.00 27.01 C ATOM 1535 CE1 HIS A 168 11.197 10.707-180.710 1.00 26.39 C ATOM 1536 NE2 HIS A 168 12.235 11.450-180.375 1.00 28.59 N ATOM 1537 N THR A 169 14.198 4.978-181.420 1.00 27.01 N ATOM 1538 CA THR A 169 15.011 3.844-181.809 1.00 27.39 C ATOM 1539 C THR A 169 15.036 3.651-183.317 1.00 26.67 C ATOM 1540 O THR A 169 14.010 3.402-183.943 1.00 27.27 O ATOM 1541 CB THR A 169 14.480 2.568-181.126 1.00 21.61 C ATOM 1542 OG1 THR A 169 14.319 2.825-179.724 1.00 21.31 O ATOM 1543 CG2 THR A 169 15.448 1.399-181.313 1.00 21.76 C ATOM 1544 N VAL A 170 16.222 3.777-183.896 1.00 23.00 N ATOM 1545 CA VAL A 170 16.384 3.608-185.328 1.00 24.50 C ATOM 1546 C VAL A 170 17.533 2.646-185.565 1.00 23.87 C ATOM 1547 O VAL A 170 18.606 2.787-184.971 1.00 24.06 O ATOM 1548 CB VAL A 170 16.693 4.956-186.016 1.00 28.84 C ATOM 1549 CG1 VAL A 170 17.006 4.729-187.489 1.00 31.27 C ATOM 1550 CG2 VAL A 170 15.502 5.915-185.844 1.00 28.22 C ATOM 1551 N ASN A 171 17.302 1.665-186.428 1.00 27.23 N ATOM 1552 CA ASN A 171 18.320 0.673-186.752 1.00 26.18 C ATOM 1553 C ASN A 171 18.821 -0.020-185.469 1.00 29.18 C ATOM 1554 O ASN A 171 20.015 -0.261-185.291 1.00 28.64 O ATOM 1555 CB ASN A 171 19.471 1.348-187.515 1.00 26.50 C ATOM 1556 CG ASN A 171 20.453 0.346-188.117 1.00 26.35 C ATOM 1557 OD1 ASN A 171 20.164 -0.850-188.214 1.00 27.05 O ATOM 1558 ND2 ASN A 171 21.618 0.837-188.528 1.00 27.34 N ATOM 1559 N GLY A 172 17.886 -0.323-184.574 1.00 31.20 N ATOM 1560 CA GLY A 172 18.225 -1.002-183.335 1.00 34.31 C ATOM 1561 C GLY A 172 18.689 -0.171-182.148 1.00 33.42 C ATOM 1562 O GLY A 172 18.621 -0.646-181.019 1.00 35.28 O ATOM 1563 N HIS A 173 19.150 1.055-182.378 1.00 23.51 N ATOM 1564 CA HIS A 173 19.632 1.888-181.284 1.00 23.90 C ATOM 1565 C HIS A 173 19.047 3.291-181.222 1.00 24.27 C ATOM 1566 O HIS A 173 18.664 3.880-182.237 1.00 22.69 O ATOM 1567 CB HIS A 173 21.158 1.970-181.337 1.00 29.77 C ATOM 1568 CG HIS A 173 21.826 0.635-181.261 1.00 32.06 C ATOM 1569 ND1 HIS A 173 21.923 -0.084-180.089 1.00 33.03 N ATOM 1570 CD2 HIS A 173 22.360 -0.149-182.228 1.00 33.20 C ATOM 1571 CE1 HIS A 173 22.483 -1.253-180.338 1.00 34.89 C ATOM 1572 NE2 HIS A 173 22.758 -1.318-181.629 1.00 33.65 N ATOM 1573 N ASN A 174 18.995 3.825-180.008 1.00 21.95 N ATOM 1574 CA ASN A 174 18.463 5.160-179.778 1.00 21.74 C ATOM 1575 C ASN A 174 19.206 6.203-180.607 1.00 22.02 C ATOM 1576 O ASN A 174 20.373 6.028-180.952 1.00 21.34 O ATOM 1577 CB ASN A 174 18.571 5.501-178.285 1.00 28.08 C ATOM 1578 CG ASN A 174 17.989 6.860-177.953 1.00 27.36 C ATOM 1579 OD1 ASN A 174 18.719 7.812-177.674 1.00 28.52 O ATOM 1580 ND2 ASN A 174 16.670 6.961-177.995 1.00 22.47 N ATOM 1581 N CYS A 175 18.512 7.281-180.943 1.00 24.25 N ATOM 1582 CA CYS A 175 19.110 8.386-181.695 1.00 26.05 C ATOM 1583 C CYS A 175 18.491 9.696-181.199 1.00 24.85 C ATOM 1584 O CYS A 175 17.374 9.707-180.669 1.00 23.09 O ATOM 1585 CB CYS A 175 18.880 8.220-183.205 1.00 30.60 C ATOM 1586 SG CYS A 175 17.156 8.215-183.678 1.00 32.55 S ATOM 1587 N GLU A 176 19.216 10.797-181.359 1.00 22.32 N ATOM 1588 CA GLU A 176 18.714 12.090-180.906 1.00 25.34 C ATOM 1589 C GLU A 176 17.961 12.783-182.037 1.00 26.03 C ATOM 1590 O GLU A 176 18.468 12.894-183.156 1.00 26.70 O ATOM 1591 CB GLU A 176 19.876 12.963-180.446 1.00 28.70 C ATOM 1592 CG GLU A 176 19.440 14.134-179.602 1.00 29.02 C ATOM 1593 CD GLU A 176 20.596 15.007-179.151 1.00 30.65 C ATOM 1594 OE1 GLU A 176 21.666 14.466-178.817 1.00 29.52 O ATOM 1595 OE2 GLU A 176 20.425 16.240-179.116 1.00 29.94 O ATOM 1596 N VAL A 177 16.744 13.240-181.757 1.00 30.06 N ATOM 1597 CA VAL A 177 15.958 13.922-182.777 1.00 30.38 C ATOM 1598 C VAL A 177 15.603 15.350-182.364 1.00 31.67 C ATOM 1599 O VAL A 177 14.950 15.565-181.347 1.00 32.47 O ATOM 1600 CB VAL A 177 14.648 13.147-183.087 1.00 17.55 C ATOM 1601 CG1 VAL A 177 13.829 13.890-184.149 1.00 19.04 C ATOM 1602 CG2 VAL A 177 14.984 11.752-183.585 1.00 16.71 C ATOM 1603 N ARG A 178 16.042 16.326-183.152 1.00 25.48 N ATOM 1604 CA ARG A 178 15.728 17.724-182.868 1.00 28.35 C ATOM 1605 C ARG A 178 15.066 18.339-184.088 1.00 27.96 C ATOM 1606 O ARG A 178 15.023 17.730-185.155 1.00 27.23 O ATOM 1607 CB ARG A 178 16.997 18.516-182.538 1.00 49.47 C ATOM 1608 CG ARG A 178 17.571 18.234-181.160 1.00 52.72 C ATOM 1609 CD ARG A 178 18.936 17.574-181.243 1.00 57.07 C ATOM 1610 NE ARG A 178 19.918 18.414-181.928 1.00 57.83 N ATOM 1611 CZ ARG A 178 21.203 18.100-182.066 1.00 56.88 C ATOM 1612 NH1 ARG A 178 21.671 16.964-181.567 1.00 58.37 N ATOM 1613 NH2 ARG A 178 22.021 18.922-182.705 1.00 59.61 N ATOM 1614 N LYS A 179 14.525 19.537-183.935 1.00 25.46 N ATOM 1615 CA LYS A 179 13.925 20.205-185.076 1.00 25.58 C ATOM 1616 C LYS A 179 15.113 20.656-185.930 1.00 24.60 C ATOM 1617 O LYS A 179 16.160 21.051-185.397 1.00 23.17 O ATOM 1618 CB LYS A 179 13.102 21.410-184.618 1.00 24.74 C ATOM 1619 CG LYS A 179 11.801 21.028-183.925 1.00 26.11 C ATOM 1620 CD LYS A 179 10.989 22.237-183.499 1.00 26.23 C ATOM 1621 CE LYS A 179 9.550 21.824-183.217 1.00 25.67 C ATOM 1622 NZ LYS A 179 8.704 22.990-182.811 1.00 21.40 N ATOM 1623 N ALA A 180 14.972 20.583-187.247 1.00 28.25 N ATOM 1624 CA ALA A 180 16.065 20.993-188.115 1.00 29.41 C ATOM 1625 C ALA A 180 16.184 22.517-188.223 1.00 30.03 C ATOM 1626 O ALA A 180 15.212 23.201-188.520 1.00 31.23 O ATOM 1627 CB ALA A 180 15.887 20.378-189.504 1.00 13.21 C ATOM 1628 N LEU A 181 17.373 23.047-187.953 1.00 23.20 N ATOM 1629 CA LEU A 181 17.608 24.481-188.086 1.00 25.05 C ATOM 1630 C LEU A 181 18.316 24.658-189.430 1.00 25.62 C ATOM 1631 O LEU A 181 18.933 23.719-189.938 1.00 24.65 O ATOM 1632 CB LEU A 181 18.499 25.005-186.958 1.00 29.97 C ATOM 1633 CG LEU A 181 17.963 24.835-185.532 1.00 32.15 C ATOM 1634 CD1 LEU A 181 18.888 25.522-184.556 1.00 32.46 C ATOM 1635 CD2 LEU A 181 16.573 25.419-185.421 1.00 32.72 C ATOM 1636 N SER A 182 18.209 25.846-190.015 1.00 27.73 N ATOM 1637 CA SER A 182 18.842 26.111-191.295 1.00 29.47 C ATOM 1638 C SER A 182 20.322 26.314-191.078 1.00 29.83 C ATOM 1639 O SER A 182 20.790 26.418-189.940 1.00 31.78 O ATOM 1640 CB SER A 182 18.265 27.375-191.938 1.00 27.44 C ATOM 1641 OG SER A 182 18.672 28.530-191.219 1.00 24.36 O ATOM 1642 N LYS A 183 21.060 26.387-192.178 1.00 34.69 N ATOM 1643 CA LYS A 183 22.494 26.594-192.101 1.00 35.66 C ATOM 1644 C LYS A 183 22.763 27.861-191.290 1.00 34.54 C ATOM 1645 O LYS A 183 23.715 27.919-190.507 1.00 35.64 O ATOM 1646 CB LYS A 183 23.077 26.714-193.513 1.00 53.02 C ATOM 1647 CG LYS A 183 24.570 26.983-193.563 1.00 54.79 C ATOM 1648 CD LYS A 183 25.123 26.784-194.967 1.00 57.45 C ATOM 1649 CE LYS A 183 25.129 25.309-195.340 1.00 59.09 C ATOM 1650 NZ LYS A 183 25.659 25.068-196.712 1.00 59.54 N ATOM 1651 N GLN A 184 21.904 28.864-191.464 1.00 25.55 N ATOM 1652 CA GLN A 184 22.062 30.130-190.753 1.00 24.02 C ATOM 1653 C GLN A 184 21.565 30.074-189.323 1.00 23.41 C ATOM 1654 O GLN A 184 22.181 30.653-188.435 1.00 24.14 O ATOM 1655 CB GLN A 184 21.357 31.266-191.503 1.00 28.90 C ATOM 1656 CG GLN A 184 22.089 31.693-192.766 1.00 26.42 C ATOM 1657 CD GLN A 184 21.355 32.762-193.555 1.00 27.22 C ATOM 1658 OE1 GLN A 184 20.513 33.485-193.019 1.00 24.58 O ATOM 1659 NE2 GLN A 184 21.686 32.878-194.833 1.00 25.25 N ATOM 1660 N GLU A 185 20.451 29.386-189.089 1.00 30.58 N ATOM 1661 CA GLU A 185 19.935 29.289-187.731 1.00 33.03 C ATOM 1662 C GLU A 185 20.966 28.585-186.852 1.00 32.65 C ATOM 1663 O GLU A 185 21.183 28.971-185.702 1.00 30.24 O ATOM 1664 CB GLU A 185 18.611 28.533-187.718 1.00 24.05 C ATOM 1665 CG GLU A 185 17.484 29.299-188.372 1.00 26.45 C ATOM 1666 CD GLU A 185 16.227 28.469-188.506 1.00 29.60 C ATOM 1667 OE1 GLU A 185 16.325 27.342-189.042 1.00 26.21 O ATOM 1668 OE2 GLU A 185 15.147 28.943-188.085 1.00 31.47 O ATOM 1669 N MET A 186 21.609 27.557-187.398 1.00 39.55 N ATOM 1670 CA MET A 186 22.633 26.842-186.648 1.00 43.18 C ATOM 1671 C MET A 186 23.689 27.853-186.232 1.00 44.49 C ATOM 1672 O MET A 186 24.077 27.931-185.066 1.00 46.44 O ATOM 1673 CB MET A 186 23.265 25.751-187.512 1.00 43.58 C ATOM 1674 CG MET A 186 22.402 24.523-187.630 1.00 45.13 C ATOM 1675 SD MET A 186 21.950 23.929-185.988 1.00 47.94 S ATOM 1676 CE MET A 186 23.512 23.250-185.456 1.00 45.16 C ATOM 1677 N ALA A 187 24.140 28.640-187.200 1.00 43.94 N ATOM 1678 CA ALA A 187 25.135 29.659-186.944 1.00 44.18 C ATOM 1679 C ALA A 187 24.663 30.599-185.834 1.00 45.41 C ATOM 1680 O ALA A 187 25.370 30.807-184.850 1.00 45.83 O ATOM 1681 CB ALA A 187 25.405 30.439-188.214 1.00 51.32 C ATOM 1682 N SER A 188 23.466 31.158-185.983 1.00 51.60 N ATOM 1683 CA SER A 188 22.928 32.076-184.979 1.00 52.46 C ATOM 1684 C SER A 188 22.736 31.437-183.602 1.00 54.03 C ATOM 1685 O SER A 188 22.509 32.136-182.613 1.00 53.59 O ATOM 1686 CB SER A 188 21.594 32.663-185.450 1.00 55.73 C ATOM 1687 OG SER A 188 21.780 33.575-186.520 1.00 52.03 O ATOM 1688 N ALA A 189 22.822 30.114-183.535 1.00 47.79 N ATOM 1689 CA ALA A 189 22.650 29.417-182.267 1.00 50.02 C ATOM 1690 C ALA A 189 23.999 29.022-181.683 1.00 51.96 C ATOM 1691 O ALA A 189 24.090 28.625-180.520 1.00 52.00 O ATOM 1692 CB ALA A 189 21.785 28.187-182.459 1.00 34.15 C ATOM 1693 N SER A 190 25.045 29.135-182.496 1.00101.74 N ATOM 1694 CA SER A 190 26.397 28.796-182.064 1.00103.33 C ATOM 1695 C SER A 190 27.185 30.057-181.703 1.00104.44 C ATOM 1696 O SER A 190 28.176 30.358-182.403 1.00104.63 O ATOM 1697 CB SER A 190 27.126 28.022-183.168 1.00 58.03 C ATOM 1698 OG SER A 190 26.475 26.796-183.456 1.00 59.02 O TER 1699 SER A 190 HETATM 1700 O HOH B 3 2.206 24.188-166.445 1.00 25.52 O HETATM 1701 O HOH B 6 4.870 22.441-165.634 1.00 17.47 O HETATM 1702 O HOH B 18 10.540 21.961-167.758 1.00 28.66 O HETATM 1703 O HOH B 33 8.534 29.517-171.519 1.00 30.41 O HETATM 1704 O HOH B 37 -2.206 37.316-180.781 1.00 37.38 O HETATM 1705 O HOH B 39 17.709 28.872-162.655 1.00 40.34 O HETATM 1706 O HOH B 42 13.020 26.040-167.149 1.00 43.66 O HETATM 1707 O HOH B 50 5.840 25.011-181.352 1.00 46.06 O HETATM 1708 O HOH B 62 30.457 23.535-148.889 1.00 30.06 O HETATM 1709 O HOH B 68 10.676 33.562-169.873 1.00 46.44 O HETATM 1710 O HOH B 75 8.492 22.551-163.988 1.00 27.30 O HETATM 1711 O HOH B 80 -2.261 34.803-187.430 1.00 30.25 O HETATM 1712 O HOH B 84 4.216 30.569-162.057 1.00 36.81 O HETATM 1713 O HOH B 98 -4.395 29.392-163.546 1.00 43.37 O HETATM 1714 O HOH B 99 3.474 36.298-165.779 1.00 42.18 O HETATM 1715 O HOH B 102 17.297 29.921-147.256 1.00 51.76 O HETATM 1716 O HOH A 197 6.941 23.036-168.729 1.00 26.53 O HETATM 1717 O HOH A 198 0.705 15.543-177.071 1.00 24.49 O HETATM 1718 O HOH A 199 8.800 19.386-174.350 1.00 30.04 O HETATM 1719 O HOH A 200 5.193 22.193-180.708 1.00 22.59 O HETATM 1720 O HOH A 201 3.815 21.546-167.912 1.00 18.24 O HETATM 1721 O HOH A 202 3.726 17.981-175.123 1.00 22.52 O HETATM 1722 O HOH A 203 -3.861 19.379-166.367 1.00 27.32 O HETATM 1723 O HOH A 204 11.864 3.907-179.576 1.00 17.82 O HETATM 1724 O HOH A 205 9.540 11.024-173.416 1.00 28.38 O HETATM 1725 O HOH A 206 -2.398 21.310-167.620 1.00 23.70 O HETATM 1726 O HOH A 207 14.556 15.435-195.317 1.00 30.62 O HETATM 1727 O HOH A 208 -1.169 24.104-185.679 1.00 26.74 O HETATM 1728 O HOH A 209 14.086 20.441-181.136 1.00 27.19 O HETATM 1729 O HOH A 210 6.346 8.470-197.181 1.00 31.01 O HETATM 1730 O HOH A 211 17.107 10.510-177.595 1.00 26.64 O HETATM 1731 O HOH A 212 11.517 19.411-167.986 1.00 27.85 O HETATM 1732 O HOH A 213 3.390 14.470-191.839 1.00 30.29 O HETATM 1733 O HOH A 214 14.659 1.252-187.556 1.00 23.95 O HETATM 1734 O HOH A 215 -7.357 36.056-175.232 1.00 30.95 O HETATM 1735 O HOH A 216 -9.162 32.943-180.144 1.00 35.74 O HETATM 1736 O HOH A 217 2.064 20.769-182.904 1.00 31.41 O HETATM 1737 O HOH A 218 13.112 13.880-179.520 1.00 27.45 O HETATM 1738 O HOH A 219 7.201 21.926-185.973 1.00 30.14 O HETATM 1739 O HOH A 220 -4.235 8.202-174.977 1.00 34.86 O HETATM 1740 O HOH A 221 16.451 22.232-182.794 1.00 33.50 O HETATM 1741 O HOH A 222 21.487 8.221-178.215 1.00 30.87 O HETATM 1742 O HOH A 223 4.547 29.154-164.386 1.00 28.72 O HETATM 1743 O HOH A 224 19.288 3.864-197.713 1.00 31.87 O HETATM 1744 O HOH A 225 15.903 4.355-177.729 1.00 26.26 O HETATM 1745 O HOH A 226 10.170 5.871-179.098 1.00 35.27 O HETATM 1746 O HOH A 227 15.601 13.009-178.962 1.00 30.14 O HETATM 1747 O HOH A 228 24.898 9.192-192.040 1.00 32.08 O HETATM 1748 O HOH A 229 1.426 9.681-184.268 1.00 39.89 O HETATM 1749 O HOH A 230 17.849 13.820-173.642 1.00 44.21 O HETATM 1750 O HOH A 231 23.291 33.267-189.239 1.00 30.77 O HETATM 1751 O HOH A 232 -5.792 25.915-186.332 1.00 36.69 O HETATM 1752 O HOH A 233 7.410 29.078-165.811 1.00 38.61 O HETATM 1753 O HOH A 234 -0.642 8.991-179.188 1.00 41.80 O HETATM 1754 O HOH A 235 15.002 -0.124-184.727 1.00 30.55 O HETATM 1755 O HOH A 236 9.214 31.340-178.212 1.00 42.74 O HETATM 1756 O HOH A 237 3.367 25.445-184.876 1.00 35.12 O HETATM 1757 O HOH A 238 -12.358 22.793-185.453 1.00 39.11 O HETATM 1758 O HOH A 239 19.455 32.811-188.200 1.00 28.04 O HETATM 1759 O HOH A 240 -15.615 29.846-178.059 1.00 37.96 O HETATM 1760 O HOH A 241 -15.410 31.052-183.612 1.00 32.08 O HETATM 1761 O HOH A 242 -0.605 13.169-165.767 1.00 33.39 O HETATM 1762 O HOH A 243 35.161 13.475-204.667 1.00 46.90 O HETATM 1763 O HOH A 244 -10.050 38.295-172.795 1.00 32.35 O HETATM 1764 O HOH A 245 11.607 22.239-192.096 1.00 28.27 O HETATM 1765 O HOH A 246 -12.124 13.442-178.919 1.00 40.47 O HETATM 1766 O HOH A 247 21.495 4.824-183.186 1.00 36.01 O HETATM 1767 O HOH A 248 5.543 23.931-184.015 1.00 37.69 O HETATM 1768 O HOH A 249 24.671 13.714-198.377 1.00 41.04 O HETATM 1769 O HOH A 250 -0.572 14.724-186.341 1.00 46.35 O HETATM 1770 O HOH A 251 0.251 12.269-191.944 1.00 36.70 O HETATM 1771 O HOH A 252 10.774 8.794-174.856 1.00 43.10 O HETATM 1772 O HOH A 253 4.138 12.122-178.784 1.00 35.75 O HETATM 1773 O HOH A 254 19.809 9.101-198.318 1.00 41.95 O HETATM 1774 O HOH A 255 13.254 19.500-196.837 1.00 39.45 O HETATM 1775 O HOH A 256 15.101 31.279-186.661 1.00 48.60 O HETATM 1776 O HOH A 257 10.426 21.834-179.826 1.00 39.89 O HETATM 1777 O HOH A 258 -4.043 8.508-181.435 1.00 45.66 O HETATM 1778 O HOH A 259 14.227 26.039-190.493 1.00 36.78 O HETATM 1779 O HOH A 260 -3.132 14.260-183.890 1.00 40.94 O HETATM 1780 O HOH A 261 29.664 14.205-188.665 1.00 45.16 O HETATM 1781 O HOH A 262 -15.896 35.473-175.861 1.00 41.58 O HETATM 1782 O HOH A 263 25.134 6.115-198.989 1.00 47.52 O HETATM 1783 O HOH A 264 8.403 9.879-199.227 1.00 38.62 O HETATM 1784 O HOH A 265 -6.162 15.991-189.675 1.00 41.10 O HETATM 1785 O HOH A 266 -12.998 25.498-186.081 1.00 34.52 O HETATM 1786 O HOH A 267 35.104 17.992-195.636 1.00 50.68 O HETATM 1787 O HOH A 268 9.468 27.517-190.148 1.00 38.77 O HETATM 1788 O HOH A 269 11.319 18.403-170.938 1.00 31.65 O HETATM 1789 O HOH A 270 6.768 18.606-196.825 1.00 47.32 O HETATM 1790 O HOH A 271 -0.104 9.241-186.143 1.00 49.31 O HETATM 1791 O HOH A 272 24.087 25.841-173.814 1.00 47.52 O HETATM 1792 O HOH A 273 23.436 25.899-179.175 1.00 42.60 O HETATM 1793 O HOH A 274 3.007 36.783-175.920 1.00 36.85 O HETATM 1794 O HOH A 275 -15.737 27.768-181.099 1.00 36.29 O HETATM 1795 O HOH A 276 24.505 6.719-191.795 1.00 42.69 O HETATM 1796 O HOH A 277 -10.240 14.686-184.736 1.00 46.37 O HETATM 1797 O HOH A 278 0.613 12.754-199.517 1.00 44.57 O HETATM 1798 O HOH A 279 5.470 15.566-202.753 1.00 46.58 O HETATM 1799 O HOH A 280 24.122 15.399-178.073 1.00 39.03 O HETATM 1800 O HOH A 281 27.323 16.148-195.480 1.00 40.97 O HETATM 1801 O HOH A 282 2.048 22.116-191.347 1.00 33.01 O HETATM 1802 O HOH A 283 31.251 14.746-190.578 1.00 47.61 O HETATM 1803 O HOH A 284 -18.509 22.458-173.724 1.00 47.44 O HETATM 1804 O HOH A 285 4.750 29.714-180.791 1.00 46.24 O HETATM 1805 O HOH A 286 1.360 18.082-176.605 1.00 37.36 O HETATM 1806 O HOH A 287 22.377 18.517-178.009 1.00 41.69 O HETATM 1807 O HOH A 288 0.692 8.026-174.081 1.00 45.75 O HETATM 1808 O HOH A 289 6.768 3.557-188.440 1.00 33.73 O HETATM 1809 O HOH A 290 -10.458 9.733-179.948 1.00 46.97 O HETATM 1810 O HOH A 291 17.512 10.866-200.421 1.00 44.07 O HETATM 1811 O HOH A 292 -3.112 16.076-186.731 1.00 45.76 O HETATM 1812 O HOH A 293 18.835 30.330-184.413 1.00 43.50 O HETATM 1813 O HOH A 294 14.921 13.426-168.609 1.00 43.77 O CONECT 153 166 CONECT 166 153 167 168 169 CONECT 167 166 CONECT 168 166 CONECT 169 166 182 CONECT 170 171 180 185 CONECT 171 170 172 178 CONECT 172 171 173 CONECT 173 172 174 175 CONECT 174 173 CONECT 175 173 176 CONECT 176 175 177 178 CONECT 177 176 CONECT 178 171 176 179 CONECT 179 178 180 CONECT 180 170 179 CONECT 181 185 186 CONECT 182 169 183 CONECT 183 182 184 186 CONECT 184 183 185 CONECT 185 170 181 184 CONECT 186 181 183 187 CONECT 187 186 188 CONECT 188 187 MASTER 291 0 1 9 11 0 0 6 1811 2 24 17 END
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Entry Information
PDB ID
1u1m
Complex Type
Protein-Nucleic Acid
PDBbind Subset
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Protein Name
Heterogeneous nuclear ribonucleoprotein A1
Ligand Name
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EC.Number
E.C.-.-.-.-
Resolution
2(Å)
Affinity (Kd/Ki/IC50)
Kd=296nM
Release Year
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Protein/NA Sequence
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Primary Reference
Journal of molecular biology. (2004) 342, pp. 743-56
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PDBsum
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UniProtKB AC
UniProt accession number (AC):
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Entrez Gene ID
NCBI Entrez Gene ID:
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