Browse entries in the PDBbind-CN Database

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Related entries of code: 2xix
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1xwsRCSB PDB    PDBbind313aa, >1XWS_1|Chain... at 100%
1yhsRCSB PDB    PDBbind273aa, >1YHS_1|Chain... at 100%
1yi3RCSB PDB    PDBbind273aa, >1YI3_1|Chain... at 100%
2c3iRCSB PDB    PDBbind313aa, >2C3I_2|Chain... at 99%
2j2iRCSB PDB    PDBbind312aa, >2J2I_1|Chain... at 99%
2o3pRCSB PDB    PDBbind293aa, >2O3P_1|Chain... at 97%
2o63RCSB PDB    PDBbind293aa, >2O63_1|Chain... at 97%
2o64RCSB PDB    PDBbind293aa, >2O64_1|Chain... at 97%
2o65RCSB PDB    PDBbind293aa, >2O65_1|Chain... at 97%
2objRCSB PDB    PDBbind333aa, >2OBJ_1|Chain... at 96%
2xiyRCSB PDB    PDBbind301aa, >2XIY_1|Chain... at 99%
2xizRCSB PDB    PDBbind301aa, >2XIZ_1|Chain... at 99%
2xj0RCSB PDB    PDBbind301aa, >2XJ0_1|Chain... at 99%
2xj1RCSB PDB    PDBbind301aa, >2XJ1_1|Chain... at 99%
2xj2RCSB PDB    PDBbind301aa, >2XJ2_1|Chain... at 99%
3bgpRCSB PDB    PDBbind333aa, >3BGP_1|Chain... at 96%
3bgqRCSB PDB    PDBbind333aa, >3BGQ_1|Chain... at 96%
3bgzRCSB PDB    PDBbind333aa, >3BGZ_1|Chain... at 96%
3bwfRCSB PDB    PDBbind313aa, >3BWF_1|Chain... at 99%
3c4eRCSB PDB    PDBbind273aa, >3C4E_1|Chains... at 100%
3dcvRCSB PDB    PDBbind328aa, >3DCV_1|Chain... at 96%
3f2aRCSB PDB    PDBbind300aa, >3F2A_1|Chain... at 100%
3jxwRCSB PDB    PDBbind294aa, >3JXW_1|Chain... at 96%
3jy0RCSB PDB    PDBbind294aa, >3JY0_1|Chain... at 96%
3jyaRCSB PDB    PDBbind294aa, >3JYA_1|Chain... at 96%
3ma3RCSB PDB    PDBbind313aa, >3MA3_1|Chain... at 99%
3r00RCSB PDB    PDBbind299aa, >3R00_1|Chain... at 95%
3r01RCSB PDB    PDBbind299aa, >3R01_1|Chain... at 95%
3r02RCSB PDB    PDBbind299aa, >3R02_1|Chain... at 95%
3r04RCSB PDB    PDBbind299aa, >3R04_1|Chain... at 95%
3uixRCSB PDB    PDBbind298aa, >3UIX_1|Chain... at 95%
3umwRCSB PDB    PDBbind298aa, >3UMW_1|Chain... at 95%
3umxRCSB PDB    PDBbind298aa, >3UMX_1|Chain... at 95%
3vbqRCSB PDB    PDBbind299aa, >3VBQ_1|Chain... at 95%
3vbtRCSB PDB    PDBbind299aa, >3VBT_1|Chain... at 95%
3vbvRCSB PDB    PDBbind299aa, >3VBV_1|Chain... at 95%
3vbwRCSB PDB    PDBbind299aa, >3VBW_1|Chain... at 95%
3vbxRCSB PDB    PDBbind299aa, >3VBX_1|Chain... at 95%
3vbyRCSB PDB    PDBbind299aa, >3VBY_1|Chain... at 95%
3vc4RCSB PDB    PDBbind299aa, >3VC4_1|Chain... at 95%
4a7cRCSB PDB    PDBbind308aa, >4A7C_1|Chain... at 92%
4aluRCSB PDB    PDBbind328aa, >4ALU_1|Chain... at 95%
4alvRCSB PDB    PDBbind328aa, >4ALV_1|Chain... at 95%
4alwRCSB PDB    PDBbind328aa, >4ALW_1|Chain... at 95%
4bznRCSB PDB    PDBbind314aa, >4BZN_1|Chain... at 99%
4bzoRCSB PDB    PDBbind314aa, >4BZO_1|Chain... at 99%
4dtkRCSB PDB    PDBbind276aa, >4DTK_1|Chain... at 100%
4enxRCSB PDB    PDBbind298aa, >4ENX_1|Chain... at 95%
4enyRCSB PDB    PDBbind298aa, >4ENY_1|Chain... at 95%
4k0yRCSB PDB    PDBbind274aa, >4K0Y_1|Chain... at 100%
4k18RCSB PDB    PDBbind277aa, >4K18_1|Chain... at 100%
4k1bRCSB PDB    PDBbind273aa, >4K1B_1|Chain... at 100%
4lm5RCSB PDB    PDBbind298aa, >4LM5_1|Chain... at 95%
4lmuRCSB PDB    PDBbind298aa, >4LMU_1|Chain... at 95%
4mbiRCSB PDB    PDBbind293aa, >4MBI_1|Chain... at 97%
4mblRCSB PDB    PDBbind293aa, >4MBL_1|Chain... at 97%
4n6yRCSB PDB    PDBbind328aa, >4N6Y_1|Chain... at 96%
4n6zRCSB PDB    PDBbind328aa, >4N6Z_1|Chain... at 96%
4n70RCSB PDB    PDBbind328aa, >4N70_1|Chain... at 96%
4rpvRCSB PDB    PDBbind410aa, >4RPV_1|Chain... *
4ty1RCSB PDB    PDBbind286aa, >4TY1_1|Chain... at 95%
4wrsRCSB PDB    PDBbind286aa, >4WRS_1|Chain... at 95%
4wsyRCSB PDB    PDBbind286aa, >4WSY_1|Chain... at 95%
4wt6RCSB PDB    PDBbind286aa, >4WT6_1|Chain... at 95%
4xh6RCSB PDB    PDBbind294aa, >4XH6_1|Chain... at 96%
4xhkRCSB PDB    PDBbind315aa, >4XHK_1|Chain... at 99%
5dgzRCSB PDB    PDBbind299aa, >5DGZ_1|Chain... at 95%
5dhjRCSB PDB    PDBbind299aa, >5DHJ_1|Chain... at 95%
5diaRCSB PDB    PDBbind299aa, >5DIA_1|Chain... at 95%
5dwrRCSB PDB    PDBbind328aa, >5DWR_1|Chain... at 96%
5eolRCSB PDB    PDBbind286aa, >5EOL_1|Chain... at 95%
5iisRCSB PDB    PDBbind277aa, >5IIS_1|Chain... at 100%
5ipjRCSB PDB    PDBbind286aa, >5IPJ_1|Chain... at 95%
5kcxRCSB PDB    PDBbind291aa, >5KCX_1|Chain... at 97%
5kziRCSB PDB    PDBbind286aa, >5KZI_1|Chain... at 95%
5o11RCSB PDB    PDBbind298aa, >5O11_1|Chain... at 95%
5texRCSB PDB    PDBbind274aa, >5TEX_1|Chain... at 100%
5toeRCSB PDB    PDBbind273aa, >5TOE_1|Chain... at 100%
5turRCSB PDB    PDBbind404aa, >5TUR_1|Chain... at 100%
5v82RCSB PDB    PDBbind299aa, >5V82_1|Chain... at 95%
6aydRCSB PDB    PDBbind334aa, >6AYD_1|Chain... at 93%
6bskRCSB PDB    PDBbind276aa, >6BSK_1|Chain... at 100%
6mt0RCSB PDB    PDBbind286aa, >6MT0_1|Chain... at 95%
6no9RCSB PDB    PDBbind273aa, >6NO9_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID2xix
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamePROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1
Ligand NameXIX
EC.Number E.C.2.7.1.37
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)IC50>5000uM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference (2011) Acta Crystallogr.,Sect.D Vol. 67: pp. 156-166
Ligand Properties
Formula C2H5N5
Molecular Weight 99.095
Exact Mass 99.055
No. of atoms 12
No. of bonds 12
Polar Surface Area 93.61
LOGP Value -1.22      (Computed with XLOGP3)
0.13      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 0
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11309  
Entrez Gene IDNCBI Entrez Gene ID: 5292  
ASDInformation of known allosteric effects of PDB entries
 
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