Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 2zv9
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2zvaRCSB PDB    PDBbind279aa, >2ZVA_1|Chain... at 96%
3a4oRCSB PDB    PDBbind286aa, >3A4O_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
1qpeRCSB PDB    PDBbindPP2
4fewRCSB PDB    PDBbindPP2
Entry Information
PDB ID2zv9
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTyrosine-protein kinase Lyn
Ligand NamePP2
EC.Number E.C.2.7.10.2
Resolution 2.76(Å)
Affinity (Kd/Ki/IC50)IC50=9nM
Release Year2008
Protein/NA SequenceCheck fasta file
Primary Reference (2009) J.Biol.Chem. Vol. 284: pp. 284-291
Ligand Properties
Formula C15H16ClN5
Molecular Weight 301.774
Exact Mass 301.109
No. of atoms 37
No. of bonds 39
Polar Surface Area 69.62
LOGP Value 3.02      (Computed with XLOGP3)
4.07      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P25911  
Entrez Gene IDNCBI Entrez Gene ID: 17096  
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2025    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com