Browse entries in the PDBbind-CN Database
HEADER PROTEIN BINDING 24-JUL-08 3DXC TITLE CRYSTAL STRUCTURE OF THE INTRACELLULAR DOMAIN OF HUMAN APP IN COMPLEX TITLE 2 WITH FE65-PTB2 COMPND MOL_ID: 1; COMPND 2 MOLECULE: AMYLOID BETA A4 PROTEIN-BINDING FAMILY B MEMBER 1; COMPND 3 CHAIN: A, C; COMPND 4 FRAGMENT: PTB2 DOMAIN, UNP RESIDUES 534-667; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: AMYLOID BETA A4 PROTEIN; COMPND 8 CHAIN: B, D; COMPND 9 FRAGMENT: APP INTRACELLULAR DOMAIN, UNP RESIDUES 739-770; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: APBB1, FE65, RIR; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) RIL; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET21D; SOURCE 11 MOL_ID: 2; SOURCE 12 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 13 ORGANISM_COMMON: HUMAN; SOURCE 14 ORGANISM_TAXID: 9606; SOURCE 15 GENE: APP, A4, AD1; SOURCE 16 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 17 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 18 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) RIL; SOURCE 19 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 20 EXPRESSION_SYSTEM_PLASMID: PETTRX_1B KEYWDS ALZHEIMER'S DISEASE, APP, AICD, FE65, PTB DOMAIN, ALZHEIMER DISEASE, KEYWDS 2 AMYLOID, APOPTOSIS, CELL ADHESION, COATED PIT, DISEASE MUTATION, KEYWDS 3 ENDOCYTOSIS, GLYCOPROTEIN, HEPARIN-BINDING, IRON, MEMBRANE, METAL- KEYWDS 4 BINDING, NOTCH SIGNALING PATHWAY, PHOSPHOPROTEIN, PROTEASE KEYWDS 5 INHIBITOR, PROTEOGLYCAN, SERINE PROTEASE INHIBITOR, TRANSMEMBRANE, KEYWDS 6 PROTEIN BINDING EXPDTA X-RAY DIFFRACTION AUTHOR J.RADZIMANOWSKI,I.SINNING,K.WILD REVDAT 4 01-FEB-17 3DXC 1 JRNL VERSN REVDAT 3 24-FEB-09 3DXC 1 VERSN REVDAT 2 18-NOV-08 3DXC 1 JRNL REVDAT 1 16-SEP-08 3DXC 0 JRNL AUTH J.RADZIMANOWSKI,B.SIMON,M.SATTLER,K.BEYREUTHER,I.SINNING, JRNL AUTH 2 K.WILD JRNL TITL STRUCTURE OF THE INTRACELLULAR DOMAIN OF THE AMYLOID JRNL TITL 2 PRECURSOR PROTEIN IN COMPLEX WITH FE65-PTB2. JRNL REF EMBO REP. V. 9 1134 2008 JRNL REFN ISSN 1469-221X JRNL PMID 18833287 JRNL DOI 10.1038/EMBOR.2008.188 REMARK 1 REMARK 1 REFERENCE 1 REMARK 1 AUTH R.RADZIMANOWSKI,K.BEYREUTHER,I.SINNING,K.WILD REMARK 1 TITL OVERPRODUCTION, PURIFICATION, CRYSTALLIZATION AND REMARK 1 TITL 2 PRELIMINARY X-RAY ANALYSIS OF HUMAN FE65-PTB2 IN COMPLEX REMARK 1 TITL 3 WITH THE AMYLOID PRECURSOR PROTEIN INTRACELLULAR DOMAIN REMARK 1 REF ACTA CRYSTALLOGR.,SECT.F V. F64 409 2008 REMARK 1 REFN ISSN 1744-3091 REMARK 1 PMID 18453713 REMARK 2 REMARK 2 RESOLUTION. 2.10 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.3.0008 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.10 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 33.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 3 NUMBER OF REFLECTIONS : 30579 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.204 REMARK 3 R VALUE (WORKING SET) : 0.202 REMARK 3 FREE R VALUE : 0.238 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 6.100 REMARK 3 FREE R VALUE TEST SET COUNT : 1997 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.10 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.15 REMARK 3 REFLECTION IN BIN (WORKING SET) : 2234 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 100.00 REMARK 3 BIN R VALUE (WORKING SET) : 0.2700 REMARK 3 BIN FREE R VALUE SET COUNT : 142 REMARK 3 BIN FREE R VALUE : 0.3120 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2395 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 236 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 41.32 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -0.07000 REMARK 3 B22 (A**2) : -0.07000 REMARK 3 B33 (A**2) : 0.10000 REMARK 3 B12 (A**2) : -0.03000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.158 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.150 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.109 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 4.055 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.951 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.935 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 2477 ; 0.013 ; 0.022 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 3366 ; 1.312 ; 1.932 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 307 ; 6.377 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 115 ;34.832 ;23.739 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 390 ;14.210 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 14 ;14.396 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 371 ; 0.089 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1908 ; 0.005 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): 1144 ; 0.206 ; 0.200 REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): 1697 ; 0.297 ; 0.200 REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): 190 ; 0.182 ; 0.200 REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): 47 ; 0.219 ; 0.200 REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): 18 ; 0.191 ; 0.200 REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 1585 ; 1.003 ; 1.500 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 2490 ; 1.710 ; 2.000 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 1008 ; 2.188 ; 3.000 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): 876 ; 3.230 ; 4.500 REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS REMARK 4 REMARK 4 3DXC COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 25-JUL-08. REMARK 100 THE RCSB ID CODE IS RCSB048606. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 19-JUL-07 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 4.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ESRF REMARK 200 BEAMLINE : ID14-2 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.00 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 4 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : MOSFLM REMARK 200 DATA SCALING SOFTWARE : SCALA REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 32612 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.100 REMARK 200 RESOLUTION RANGE LOW (A) : 33.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 200 DATA REDUNDANCY : 11.100 REMARK 200 R MERGE (I) : 0.06000 REMARK 200 R SYM (I) : 0.06000 REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 28.8000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.10 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.21 REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : 11.20 REMARK 200 R MERGE FOR SHELL (I) : 0.46500 REMARK 200 R SYM FOR SHELL (I) : 0.46500 REMARK 200 <I/SIGMA(I)> FOR SHELL : 4.700 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 65.93 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.61 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 3.2 M NACL,0.1 M SODIUM ACETATE , PH REMARK 280 4.6, VAPOR DIFFUSION, TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 61 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+1/3 REMARK 290 3555 -X+Y,-X,Z+2/3 REMARK 290 4555 -X,-Y,Z+1/2 REMARK 290 5555 Y,-X+Y,Z+5/6 REMARK 290 6555 X-Y,X,Z+1/6 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 24.95000 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 49.90000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 37.42500 REMARK 290 SMTRY1 5 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 62.37500 REMARK 290 SMTRY1 6 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 12.47500 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1, 2 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 300 REMARK: THE ASYMMETRIC UNIT CONTAINS TWO COPIES OF A PROTEIN REMARK 300 PROTEIN COMPLEX (ONE BIOMOLECULE 1 BINDS ONE BIOMOLECULE 2). REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2100 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 8190 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -16.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 REMARK 350 BIOMOLECULE: 2 REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2120 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 7690 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -13.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, D REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ALA A 534 REMARK 465 PRO A 535 REMARK 465 LYS A 536 REMARK 465 GLN A 667 REMARK 465 HIS A 668 REMARK 465 HIS A 669 REMARK 465 HIS A 670 REMARK 465 HIS A 671 REMARK 465 HIS A 672 REMARK 465 HIS A 673 REMARK 465 GLY B 661 REMARK 465 ALA B 662 REMARK 465 MET B 663 REMARK 465 ASP B 664 REMARK 465 ALA B 665 REMARK 465 GLN B 694 REMARK 465 ASN B 695 REMARK 465 ALA C 534 REMARK 465 PRO C 535 REMARK 465 LYS C 536 REMARK 465 ASN C 537 REMARK 465 GLU C 538 REMARK 465 LEU C 539 REMARK 465 VAL C 540 REMARK 465 GLN C 541 REMARK 465 LYS C 542 REMARK 465 SER C 666 REMARK 465 GLN C 667 REMARK 465 HIS C 668 REMARK 465 HIS C 669 REMARK 465 HIS C 670 REMARK 465 HIS C 671 REMARK 465 HIS C 672 REMARK 465 HIS C 673 REMARK 465 GLY D 661 REMARK 465 ALA D 662 REMARK 465 MET D 663 REMARK 465 ASP D 664 REMARK 465 ALA D 665 REMARK 465 ALA D 666 REMARK 465 MET D 693 REMARK 465 GLN D 694 REMARK 465 ASN D 695 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 PHE D 690 2.22 -67.14 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CHIRAL CENTERS REMARK 500 REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16) REMARK 500 REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS REMARK 500 GLN A 595 24.3 L L OUTSIDE RANGE REMARK 500 GLN A 596 23.4 L L OUTSIDE RANGE REMARK 500 REMARK 500 REMARK: NULL REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 HOH D 147 DISTANCE = 5.10 ANGSTROMS REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 3DXD RELATED DB: PDB REMARK 900 RELATED ID: 3DXE RELATED DB: PDB DBREF 3DXC A 534 667 UNP O00213 APBB1_HUMAN 534 667 DBREF 3DXC B 664 695 UNP P05067 A4_HUMAN 739 770 DBREF 3DXC C 534 667 UNP O00213 APBB1_HUMAN 534 667 DBREF 3DXC D 664 695 UNP P05067 A4_HUMAN 739 770 SEQADV 3DXC HIS A 668 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS A 669 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS A 670 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS A 671 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS A 672 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS A 673 UNP O00213 EXPRESSION TAG SEQADV 3DXC GLY B 661 UNP P05067 EXPRESSION TAG SEQADV 3DXC ALA B 662 UNP P05067 EXPRESSION TAG SEQADV 3DXC MET B 663 UNP P05067 EXPRESSION TAG SEQADV 3DXC HIS C 668 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS C 669 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS C 670 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS C 671 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS C 672 UNP O00213 EXPRESSION TAG SEQADV 3DXC HIS C 673 UNP O00213 EXPRESSION TAG SEQADV 3DXC GLY D 661 UNP P05067 EXPRESSION TAG SEQADV 3DXC ALA D 662 UNP P05067 EXPRESSION TAG SEQADV 3DXC MET D 663 UNP P05067 EXPRESSION TAG SEQRES 1 A 140 ALA PRO LYS ASN GLU LEU VAL GLN LYS PHE GLN VAL TYR SEQRES 2 A 140 TYR LEU GLY ASN VAL PRO VAL ALA LYS PRO VAL GLY VAL SEQRES 3 A 140 ASP VAL ILE ASN GLY ALA LEU GLU SER VAL LEU SER SER SEQRES 4 A 140 SER SER ARG GLU GLN TRP THR PRO SER HIS VAL SER VAL SEQRES 5 A 140 ALA PRO ALA THR LEU THR ILE LEU HIS GLN GLN THR GLU SEQRES 6 A 140 ALA VAL LEU GLY GLU CYS ARG VAL ARG PHE LEU SER PHE SEQRES 7 A 140 LEU ALA VAL GLY ARG ASP VAL HIS THR PHE ALA PHE ILE SEQRES 8 A 140 MET ALA ALA GLY PRO ALA SER PHE CYS CYS HIS MET PHE SEQRES 9 A 140 TRP CYS GLU PRO ASN ALA ALA SER LEU SER GLU ALA VAL SEQRES 10 A 140 GLN ALA ALA CYS MET LEU ARG TYR GLN LYS CYS LEU ASP SEQRES 11 A 140 ALA ARG SER GLN HIS HIS HIS HIS HIS HIS SEQRES 1 B 35 GLY ALA MET ASP ALA ALA VAL THR PRO GLU GLU ARG HIS SEQRES 2 B 35 LEU SER LYS MET GLN GLN ASN GLY TYR GLU ASN PRO THR SEQRES 3 B 35 TYR LYS PHE PHE GLU GLN MET GLN ASN SEQRES 1 C 140 ALA PRO LYS ASN GLU LEU VAL GLN LYS PHE GLN VAL TYR SEQRES 2 C 140 TYR LEU GLY ASN VAL PRO VAL ALA LYS PRO VAL GLY VAL SEQRES 3 C 140 ASP VAL ILE ASN GLY ALA LEU GLU SER VAL LEU SER SER SEQRES 4 C 140 SER SER ARG GLU GLN TRP THR PRO SER HIS VAL SER VAL SEQRES 5 C 140 ALA PRO ALA THR LEU THR ILE LEU HIS GLN GLN THR GLU SEQRES 6 C 140 ALA VAL LEU GLY GLU CYS ARG VAL ARG PHE LEU SER PHE SEQRES 7 C 140 LEU ALA VAL GLY ARG ASP VAL HIS THR PHE ALA PHE ILE SEQRES 8 C 140 MET ALA ALA GLY PRO ALA SER PHE CYS CYS HIS MET PHE SEQRES 9 C 140 TRP CYS GLU PRO ASN ALA ALA SER LEU SER GLU ALA VAL SEQRES 10 C 140 GLN ALA ALA CYS MET LEU ARG TYR GLN LYS CYS LEU ASP SEQRES 11 C 140 ALA ARG SER GLN HIS HIS HIS HIS HIS HIS SEQRES 1 D 35 GLY ALA MET ASP ALA ALA VAL THR PRO GLU GLU ARG HIS SEQRES 2 D 35 LEU SER LYS MET GLN GLN ASN GLY TYR GLU ASN PRO THR SEQRES 3 D 35 TYR LYS PHE PHE GLU GLN MET GLN ASN FORMUL 5 HOH *236(H2 O) HELIX 1 1 GLY A 558 SER A 572 1 15 HELIX 2 2 SER A 573 TRP A 578 5 6 HELIX 3 3 ALA A 643 SER A 666 1 24 HELIX 4 4 THR B 668 ASN B 680 1 13 HELIX 5 5 ASN B 684 MET B 693 1 10 HELIX 6 6 GLY C 558 SER C 572 1 15 HELIX 7 7 SER C 574 TRP C 578 5 5 HELIX 8 8 ALA C 643 ALA C 664 1 22 HELIX 9 9 THR D 668 ASN D 680 1 13 HELIX 10 10 ASN D 684 PHE D 690 1 7 SHEET 1 A 8 VAL A 600 ARG A 605 0 SHEET 2 A 8 THR A 589 HIS A 594 -1 N ILE A 592 O LEU A 601 SHEET 3 A 8 THR A 579 VAL A 585 -1 N SER A 584 O THR A 591 SHEET 4 A 8 VAL A 540 VAL A 553 -1 N TYR A 547 O THR A 579 SHEET 5 A 8 SER A 631 TRP A 638 -1 O CYS A 634 N VAL A 551 SHEET 6 A 8 THR A 620 GLY A 628 -1 N MET A 625 O CYS A 633 SHEET 7 A 8 LEU A 609 VAL A 614 -1 N PHE A 611 O ILE A 624 SHEET 8 A 8 TYR B 682 GLU B 683 -1 O TYR B 682 N LEU A 612 SHEET 1 B 8 VAL C 600 ARG C 605 0 SHEET 2 B 8 THR C 589 HIS C 594 -1 N ILE C 592 O LEU C 601 SHEET 3 B 8 THR C 579 VAL C 585 -1 N SER C 584 O THR C 591 SHEET 4 B 8 GLN C 544 VAL C 553 -1 N TYR C 547 O THR C 579 SHEET 5 B 8 SER C 631 GLU C 640 -1 O CYS C 634 N VAL C 551 SHEET 6 B 8 THR C 620 GLY C 628 -1 N PHE C 623 O HIS C 635 SHEET 7 B 8 LEU C 609 VAL C 614 -1 N PHE C 611 O ILE C 624 SHEET 8 B 8 TYR D 682 GLU D 683 -1 O TYR D 682 N LEU C 612 CISPEP 1 GLU A 640 PRO A 641 0 5.97 CISPEP 2 GLU C 640 PRO C 641 0 0.85 CRYST1 114.320 114.320 74.850 90.00 90.00 120.00 P 61 12 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.008747 0.005050 0.000000 0.00000 SCALE2 0.000000 0.010101 0.000000 0.00000 SCALE3 0.000000 0.000000 0.013360 0.00000 ATOM 1 N ASN A 537 -32.304 41.221 14.150 1.00 78.74 N ATOM 2 CA ASN A 537 -31.307 41.137 15.255 1.00 78.67 C ATOM 3 C ASN A 537 -29.933 41.684 14.825 1.00 78.35 C ATOM 4 O ASN A 537 -29.760 42.900 14.724 1.00 78.34 O ATOM 5 CB ASN A 537 -31.217 39.693 15.780 1.00 78.93 C ATOM 6 CG ASN A 537 -30.612 39.603 17.188 1.00 79.49 C ATOM 7 OD1 ASN A 537 -30.370 40.619 17.855 1.00 78.67 O ATOM 8 ND2 ASN A 537 -30.378 38.370 17.646 1.00 79.49 N ATOM 9 N GLU A 538 -28.976 40.797 14.544 1.00 77.88 N ATOM 10 CA GLU A 538 -27.595 41.205 14.229 1.00 77.61 C ATOM 11 C GLU A 538 -27.475 42.094 12.987 1.00 76.92 C ATOM 12 O GLU A 538 -28.288 41.999 12.065 1.00 77.13 O ATOM 13 CB GLU A 538 -26.664 39.990 14.117 1.00 77.49 C ATOM 14 CG GLU A 538 -27.182 38.857 13.247 1.00 78.01 C ATOM 15 CD GLU A 538 -26.174 37.732 13.083 1.00 78.55 C ATOM 16 OE1 GLU A 538 -25.446 37.434 14.057 1.00 80.12 O ATOM 17 OE2 GLU A 538 -26.111 37.140 11.977 1.00 79.77 O ATOM 18 N LEU A 539 -26.462 42.958 12.981 1.00 76.04 N ATOM 19 CA LEU A 539 -26.189 43.845 11.844 1.00 75.21 C ATOM 20 C LEU A 539 -25.329 43.150 10.787 1.00 74.81 C ATOM 21 O LEU A 539 -25.489 43.390 9.586 1.00 74.83 O ATOM 22 CB LEU A 539 -25.511 45.140 12.309 1.00 74.91 C ATOM 23 CG LEU A 539 -26.314 46.051 13.242 1.00 74.03 C ATOM 24 CD1 LEU A 539 -25.386 46.896 14.098 1.00 73.66 C ATOM 25 CD2 LEU A 539 -27.305 46.922 12.469 1.00 73.24 C ATOM 26 N VAL A 540 -24.412 42.303 11.248 1.00 74.07 N ATOM 27 CA VAL A 540 -23.548 41.517 10.369 1.00 73.43 C ATOM 28 C VAL A 540 -23.363 40.115 10.960 1.00 73.06 C ATOM 29 O VAL A 540 -23.564 39.909 12.172 1.00 73.08 O ATOM 30 CB VAL A 540 -22.143 42.192 10.114 1.00 73.43 C ATOM 31 CG1 VAL A 540 -22.288 43.531 9.383 1.00 72.79 C ATOM 32 CG2 VAL A 540 -21.347 42.364 11.421 1.00 73.08 C ATOM 33 N GLN A 541 -22.978 39.168 10.101 1.00 72.21 N ATOM 34 CA GLN A 541 -22.697 37.792 10.519 1.00 71.60 C ATOM 35 C GLN A 541 -21.561 37.741 11.553 1.00 70.53 C ATOM 36 O GLN A 541 -20.613 38.542 11.504 1.00 70.61 O ATOM 37 CB GLN A 541 -22.368 36.904 9.313 1.00 71.71 C ATOM 38 CG GLN A 541 -23.447 36.870 8.212 1.00 72.07 C ATOM 39 CD GLN A 541 -23.066 35.991 7.010 1.00 72.65 C ATOM 40 OE1 GLN A 541 -23.864 35.821 6.080 1.00 73.58 O ATOM 41 NE2 GLN A 541 -21.846 35.433 7.025 1.00 72.47 N ATOM 42 N LYS A 542 -21.681 36.797 12.485 1.00 68.91 N ATOM 43 CA LYS A 542 -20.777 36.667 13.625 1.00 67.25 C ATOM 44 C LYS A 542 -19.301 36.508 13.223 1.00 66.00 C ATOM 45 O LYS A 542 -18.973 35.916 12.181 1.00 66.06 O ATOM 46 CB LYS A 542 -21.237 35.502 14.508 1.00 67.40 C ATOM 47 CG LYS A 542 -22.687 35.636 14.958 1.00 68.27 C ATOM 48 CD LYS A 542 -23.336 34.299 15.297 1.00 69.20 C ATOM 49 CE LYS A 542 -24.813 34.485 15.624 1.00 69.75 C ATOM 50 NZ LYS A 542 -25.297 33.470 16.595 1.00 69.61 N ATOM 51 N PHE A 543 -18.429 37.052 14.067 1.00 64.00 N ATOM 52 CA PHE A 543 -16.978 37.056 13.861 1.00 61.98 C ATOM 53 C PHE A 543 -16.333 35.892 14.574 1.00 61.45 C ATOM 54 O PHE A 543 -16.534 35.714 15.779 1.00 61.88 O ATOM 55 CB PHE A 543 -16.390 38.368 14.377 1.00 60.59 C ATOM 56 CG PHE A 543 -16.868 39.559 13.622 1.00 59.01 C ATOM 57 CD1 PHE A 543 -16.214 39.968 12.467 1.00 57.47 C ATOM 58 CD2 PHE A 543 -18.004 40.240 14.027 1.00 55.86 C ATOM 59 CE1 PHE A 543 -16.671 41.058 11.754 1.00 56.88 C ATOM 60 CE2 PHE A 543 -18.466 41.325 13.326 1.00 55.46 C ATOM 61 CZ PHE A 543 -17.797 41.742 12.186 1.00 56.88 C ATOM 62 N GLN A 544 -15.562 35.101 13.834 1.00 60.44 N ATOM 63 CA GLN A 544 -14.878 33.938 14.405 1.00 59.57 C ATOM 64 C GLN A 544 -13.502 34.352 14.907 1.00 58.01 C ATOM 65 O GLN A 544 -12.554 34.510 14.135 1.00 58.45 O ATOM 66 CB GLN A 544 -14.792 32.777 13.394 1.00 60.32 C ATOM 67 CG GLN A 544 -16.153 32.175 12.981 1.00 62.61 C ATOM 68 CD GLN A 544 -16.910 31.522 14.147 1.00 65.09 C ATOM 69 OE1 GLN A 544 -16.350 31.294 15.225 1.00 66.46 O ATOM 70 NE2 GLN A 544 -18.187 31.216 13.926 1.00 66.08 N ATOM 71 N VAL A 545 -13.413 34.556 16.218 1.00 55.84 N ATOM 72 CA VAL A 545 -12.211 35.100 16.851 1.00 52.69 C ATOM 73 C VAL A 545 -11.999 34.323 18.134 1.00 50.92 C ATOM 74 O VAL A 545 -12.797 33.433 18.464 1.00 51.24 O ATOM 75 CB VAL A 545 -12.345 36.640 17.133 1.00 52.82 C ATOM 76 CG1 VAL A 545 -12.541 37.416 15.841 1.00 51.59 C ATOM 77 CG2 VAL A 545 -13.480 36.953 18.113 1.00 52.34 C ATOM 78 N TYR A 546 -10.937 34.640 18.863 1.00 48.60 N ATOM 79 CA TYR A 546 -10.733 34.014 20.154 1.00 46.13 C ATOM 80 C TYR A 546 -11.086 34.982 21.275 1.00 43.74 C ATOM 81 O TYR A 546 -10.631 36.122 21.293 1.00 42.55 O ATOM 82 CB TYR A 546 -9.312 33.450 20.290 1.00 47.88 C ATOM 83 CG TYR A 546 -8.956 32.491 19.164 1.00 49.86 C ATOM 84 CD1 TYR A 546 -8.490 32.972 17.938 1.00 51.70 C ATOM 85 CD2 TYR A 546 -9.111 31.109 19.314 1.00 51.40 C ATOM 86 CE1 TYR A 546 -8.168 32.104 16.888 1.00 53.30 C ATOM 87 CE2 TYR A 546 -8.792 30.226 18.263 1.00 53.05 C ATOM 88 CZ TYR A 546 -8.319 30.738 17.054 1.00 52.64 C ATOM 89 OH TYR A 546 -8.008 29.899 15.993 1.00 53.81 O ATOM 90 N TYR A 547 -11.932 34.515 22.188 1.00 40.90 N ATOM 91 CA TYR A 547 -12.277 35.261 23.370 1.00 38.59 C ATOM 92 C TYR A 547 -11.238 34.940 24.424 1.00 37.32 C ATOM 93 O TYR A 547 -11.094 33.789 24.832 1.00 36.99 O ATOM 94 CB TYR A 547 -13.662 34.865 23.886 1.00 37.62 C ATOM 95 CG TYR A 547 -14.186 35.757 25.008 1.00 36.43 C ATOM 96 CD1 TYR A 547 -14.005 37.146 24.975 1.00 34.21 C ATOM 97 CD2 TYR A 547 -14.890 35.213 26.082 1.00 36.20 C ATOM 98 CE1 TYR A 547 -14.492 37.967 25.995 1.00 34.09 C ATOM 99 CE2 TYR A 547 -15.393 36.031 27.105 1.00 36.64 C ATOM 100 CZ TYR A 547 -15.193 37.403 27.051 1.00 35.79 C ATOM 101 OH TYR A 547 -15.694 38.206 28.053 1.00 35.32 O ATOM 102 N LEU A 548 -10.521 35.971 24.850 1.00 36.00 N ATOM 103 CA LEU A 548 -9.458 35.829 25.833 1.00 34.83 C ATOM 104 C LEU A 548 -10.004 36.002 27.247 1.00 34.38 C ATOM 105 O LEU A 548 -9.322 35.714 28.221 1.00 35.07 O ATOM 106 CB LEU A 548 -8.346 36.850 25.545 1.00 34.37 C ATOM 107 CG LEU A 548 -7.722 36.828 24.142 1.00 34.41 C ATOM 108 CD1 LEU A 548 -6.819 38.038 23.877 1.00 33.95 C ATOM 109 CD2 LEU A 548 -6.964 35.538 23.919 1.00 33.02 C ATOM 110 N GLY A 549 -11.229 36.502 27.360 1.00 33.75 N ATOM 111 CA GLY A 549 -11.873 36.654 28.655 1.00 32.42 C ATOM 112 C GLY A 549 -12.061 38.111 29.020 1.00 32.53 C ATOM 113 O GLY A 549 -11.938 39.012 28.174 1.00 31.90 O ATOM 114 N ASN A 550 -12.373 38.340 30.289 1.00 32.21 N ATOM 115 CA ASN A 550 -12.596 39.679 30.781 1.00 32.92 C ATOM 116 C ASN A 550 -11.985 39.851 32.163 1.00 33.22 C ATOM 117 O ASN A 550 -11.855 38.880 32.915 1.00 33.86 O ATOM 118 CB ASN A 550 -14.086 40.035 30.730 1.00 32.69 C ATOM 119 CG ASN A 550 -14.939 39.163 31.649 1.00 34.88 C ATOM 120 OD1 ASN A 550 -14.921 39.337 32.867 1.00 35.96 O ATOM 121 ND2 ASN A 550 -15.692 38.218 31.059 1.00 35.37 N ATOM 122 N VAL A 551 -11.568 41.076 32.462 1.00 33.02 N ATOM 123 CA VAL A 551 -10.913 41.418 33.721 1.00 33.38 C ATOM 124 C VAL A 551 -11.446 42.781 34.170 1.00 33.19 C ATOM 125 O VAL A 551 -11.835 43.604 33.327 1.00 31.95 O ATOM 126 CB VAL A 551 -9.348 41.449 33.619 1.00 33.75 C ATOM 127 CG1 VAL A 551 -8.761 40.060 33.230 1.00 35.89 C ATOM 128 CG2 VAL A 551 -8.845 42.541 32.657 1.00 33.38 C ATOM 129 N PRO A 552 -11.518 43.012 35.494 1.00 33.33 N ATOM 130 CA PRO A 552 -11.874 44.362 35.931 1.00 33.21 C ATOM 131 C PRO A 552 -10.760 45.365 35.583 1.00 32.60 C ATOM 132 O PRO A 552 -9.586 45.014 35.573 1.00 32.37 O ATOM 133 CB PRO A 552 -11.999 44.230 37.461 1.00 33.11 C ATOM 134 CG PRO A 552 -11.237 43.038 37.815 1.00 34.47 C ATOM 135 CD PRO A 552 -11.302 42.100 36.635 1.00 33.83 C ATOM 136 N VAL A 553 -11.137 46.600 35.300 1.00 32.41 N ATOM 137 CA VAL A 553 -10.144 47.666 35.065 1.00 31.24 C ATOM 138 C VAL A 553 -10.599 48.896 35.835 1.00 31.97 C ATOM 139 O VAL A 553 -11.770 48.986 36.227 1.00 30.80 O ATOM 140 CB VAL A 553 -9.955 47.980 33.552 1.00 31.18 C ATOM 141 CG1 VAL A 553 -9.215 46.807 32.821 1.00 27.32 C ATOM 142 CG2 VAL A 553 -11.296 48.315 32.889 1.00 29.33 C ATOM 143 N ALA A 554 -9.680 49.835 36.036 1.00 32.25 N ATOM 144 CA ALA A 554 -9.890 50.979 36.944 1.00 33.13 C ATOM 145 C ALA A 554 -10.619 52.150 36.343 1.00 33.54 C ATOM 146 O ALA A 554 -11.228 52.942 37.079 1.00 34.15 O ATOM 147 CB ALA A 554 -8.541 51.451 37.513 1.00 33.05 C ATOM 148 N LYS A 555 -10.579 52.262 35.014 1.00 33.28 N ATOM 149 CA LYS A 555 -11.049 53.457 34.325 1.00 33.90 C ATOM 150 C LYS A 555 -11.937 53.070 33.123 1.00 32.46 C ATOM 151 O LYS A 555 -11.773 51.994 32.555 1.00 31.18 O ATOM 152 CB LYS A 555 -9.833 54.299 33.837 1.00 33.74 C ATOM 153 CG LYS A 555 -8.883 54.783 34.945 1.00 37.51 C ATOM 154 CD LYS A 555 -7.751 55.740 34.419 1.00 38.10 C ATOM 155 CE LYS A 555 -6.576 55.012 33.738 1.00 45.23 C ATOM 156 NZ LYS A 555 -5.452 55.888 33.139 1.00 44.08 N ATOM 157 N PRO A 556 -12.884 53.952 32.738 1.00 31.86 N ATOM 158 CA PRO A 556 -13.762 53.663 31.600 1.00 31.40 C ATOM 159 C PRO A 556 -13.083 53.751 30.222 1.00 30.75 C ATOM 160 O PRO A 556 -13.616 53.212 29.254 1.00 29.53 O ATOM 161 CB PRO A 556 -14.836 54.757 31.702 1.00 31.37 C ATOM 162 CG PRO A 556 -14.129 55.902 32.345 1.00 31.96 C ATOM 163 CD PRO A 556 -13.195 55.264 33.351 1.00 31.73 C ATOM 164 N VAL A 557 -11.939 54.442 30.138 1.00 31.08 N ATOM 165 CA VAL A 557 -11.273 54.716 28.838 1.00 31.01 C ATOM 166 C VAL A 557 -9.732 54.624 28.913 1.00 30.42 C ATOM 167 O VAL A 557 -9.146 54.714 29.984 1.00 30.81 O ATOM 168 CB VAL A 557 -11.667 56.119 28.236 1.00 30.88 C ATOM 169 CG1 VAL A 557 -13.201 56.293 28.081 1.00 31.76 C ATOM 170 CG2 VAL A 557 -11.083 57.251 29.069 1.00 32.46 C ATOM 171 N GLY A 558 -9.101 54.428 27.768 1.00 30.36 N ATOM 172 CA GLY A 558 -7.640 54.630 27.623 1.00 30.44 C ATOM 173 C GLY A 558 -6.973 53.462 26.935 1.00 29.96 C ATOM 174 O GLY A 558 -7.217 52.319 27.319 1.00 29.15 O ATOM 175 N VAL A 559 -6.146 53.720 25.911 1.00 29.92 N ATOM 176 CA VAL A 559 -5.388 52.625 25.291 1.00 29.58 C ATOM 177 C VAL A 559 -4.396 51.980 26.283 1.00 28.48 C ATOM 178 O VAL A 559 -4.109 50.787 26.201 1.00 28.51 O ATOM 179 CB VAL A 559 -4.680 52.997 23.924 1.00 30.28 C ATOM 180 CG1 VAL A 559 -5.698 53.220 22.827 1.00 31.83 C ATOM 181 CG2 VAL A 559 -3.781 54.207 24.062 1.00 31.64 C ATOM 182 N ASP A 560 -3.877 52.768 27.210 1.00 28.47 N ATOM 183 CA ASP A 560 -3.025 52.220 28.270 1.00 29.12 C ATOM 184 C ASP A 560 -3.760 51.196 29.145 1.00 28.18 C ATOM 185 O ASP A 560 -3.168 50.211 29.559 1.00 27.06 O ATOM 186 CB ASP A 560 -2.499 53.329 29.173 1.00 29.35 C ATOM 187 CG ASP A 560 -3.608 54.097 29.861 1.00 34.74 C ATOM 188 OD1 ASP A 560 -4.601 54.440 29.187 1.00 40.72 O ATOM 189 OD2 ASP A 560 -3.483 54.379 31.079 1.00 37.91 O ATOM 190 N VAL A 561 -5.044 51.466 29.427 1.00 27.60 N ATOM 191 CA VAL A 561 -5.876 50.574 30.240 1.00 27.32 C ATOM 192 C VAL A 561 -6.063 49.250 29.527 1.00 26.46 C ATOM 193 O VAL A 561 -5.855 48.204 30.115 1.00 26.50 O ATOM 194 CB VAL A 561 -7.276 51.214 30.557 1.00 26.96 C ATOM 195 CG1 VAL A 561 -8.179 50.234 31.288 1.00 26.68 C ATOM 196 CG2 VAL A 561 -7.085 52.454 31.416 1.00 27.04 C ATOM 197 N ILE A 562 -6.438 49.295 28.253 1.00 26.19 N ATOM 198 CA ILE A 562 -6.693 48.069 27.523 1.00 25.75 C ATOM 199 C ILE A 562 -5.421 47.292 27.203 1.00 25.16 C ATOM 200 O ILE A 562 -5.442 46.073 27.213 1.00 24.80 O ATOM 201 CB ILE A 562 -7.548 48.268 26.219 1.00 26.96 C ATOM 202 CG1 ILE A 562 -6.791 49.068 25.143 1.00 28.22 C ATOM 203 CG2 ILE A 562 -8.974 48.868 26.533 1.00 24.67 C ATOM 204 CD1 ILE A 562 -6.240 48.172 23.990 1.00 31.13 C ATOM 205 N ASN A 563 -4.314 47.983 26.953 1.00 25.25 N ATOM 206 CA ASN A 563 -3.044 47.268 26.722 1.00 25.43 C ATOM 207 C ASN A 563 -2.486 46.643 27.982 1.00 25.57 C ATOM 208 O ASN A 563 -1.877 45.602 27.905 1.00 26.12 O ATOM 209 CB ASN A 563 -2.000 48.175 26.020 1.00 25.29 C ATOM 210 CG ASN A 563 -2.313 48.362 24.536 1.00 22.84 C ATOM 211 OD1 ASN A 563 -2.290 47.414 23.788 1.00 25.62 O ATOM 212 ND2 ASN A 563 -2.651 49.578 24.130 1.00 23.16 N ATOM 213 N GLY A 564 -2.725 47.271 29.141 1.00 26.44 N ATOM 214 CA GLY A 564 -2.379 46.663 30.422 1.00 27.37 C ATOM 215 C GLY A 564 -3.165 45.387 30.651 1.00 27.80 C ATOM 216 O GLY A 564 -2.587 44.371 31.041 1.00 27.67 O ATOM 217 N ALA A 565 -4.480 45.438 30.364 1.00 27.95 N ATOM 218 CA ALA A 565 -5.376 44.275 30.473 1.00 27.82 C ATOM 219 C ALA A 565 -4.954 43.132 29.533 1.00 28.35 C ATOM 220 O ALA A 565 -4.874 41.976 29.963 1.00 28.25 O ATOM 221 CB ALA A 565 -6.831 44.701 30.188 1.00 28.29 C ATOM 222 N LEU A 566 -4.657 43.461 28.265 1.00 27.76 N ATOM 223 CA LEU A 566 -4.190 42.477 27.269 1.00 28.20 C ATOM 224 C LEU A 566 -2.888 41.788 27.666 1.00 28.41 C ATOM 225 O LEU A 566 -2.798 40.568 27.646 1.00 28.71 O ATOM 226 CB LEU A 566 -3.997 43.143 25.896 1.00 28.35 C ATOM 227 CG LEU A 566 -5.290 43.543 25.175 1.00 28.00 C ATOM 228 CD1 LEU A 566 -5.041 44.502 24.049 1.00 24.74 C ATOM 229 CD2 LEU A 566 -5.978 42.280 24.698 1.00 27.34 C ATOM 230 N GLU A 567 -1.874 42.573 28.018 1.00 29.43 N ATOM 231 CA GLU A 567 -0.606 41.989 28.492 1.00 29.86 C ATOM 232 C GLU A 567 -0.820 41.037 29.687 1.00 30.47 C ATOM 233 O GLU A 567 -0.258 39.958 29.714 1.00 30.87 O ATOM 234 CB GLU A 567 0.414 43.083 28.810 1.00 29.89 C ATOM 235 CG GLU A 567 0.949 43.781 27.547 1.00 28.82 C ATOM 236 CD GLU A 567 1.792 44.987 27.815 1.00 28.15 C ATOM 237 OE1 GLU A 567 2.005 45.319 28.978 1.00 28.26 O ATOM 238 OE2 GLU A 567 2.275 45.627 26.855 1.00 27.67 O ATOM 239 N SER A 568 -1.645 41.432 30.651 1.00 30.88 N ATOM 240 CA SER A 568 -1.936 40.585 31.791 1.00 31.87 C ATOM 241 C SER A 568 -2.558 39.250 31.415 1.00 32.20 C ATOM 242 O SER A 568 -2.039 38.207 31.834 1.00 32.35 O ATOM 243 CB SER A 568 -2.808 41.318 32.807 1.00 32.24 C ATOM 244 OG SER A 568 -1.998 42.256 33.500 1.00 35.93 O ATOM 245 N VAL A 569 -3.643 39.269 30.627 1.00 32.19 N ATOM 246 CA VAL A 569 -4.297 38.029 30.204 1.00 32.56 C ATOM 247 C VAL A 569 -3.421 37.145 29.278 1.00 32.86 C ATOM 248 O VAL A 569 -3.410 35.910 29.398 1.00 33.47 O ATOM 249 CB VAL A 569 -5.734 38.270 29.605 1.00 32.72 C ATOM 250 CG1 VAL A 569 -5.689 38.814 28.183 1.00 31.15 C ATOM 251 CG2 VAL A 569 -6.506 36.990 29.626 1.00 33.77 C ATOM 252 N LEU A 570 -2.676 37.766 28.373 1.00 32.79 N ATOM 253 CA LEU A 570 -1.791 37.001 27.485 1.00 33.59 C ATOM 254 C LEU A 570 -0.667 36.311 28.252 1.00 34.19 C ATOM 255 O LEU A 570 -0.241 35.240 27.874 1.00 34.18 O ATOM 256 CB LEU A 570 -1.205 37.891 26.373 1.00 33.50 C ATOM 257 CG LEU A 570 -2.211 38.436 25.345 1.00 33.90 C ATOM 258 CD1 LEU A 570 -1.564 39.499 24.484 1.00 35.01 C ATOM 259 CD2 LEU A 570 -2.787 37.342 24.452 1.00 34.24 C ATOM 260 N SER A 571 -0.205 36.928 29.332 1.00 35.62 N ATOM 261 CA SER A 571 0.879 36.371 30.134 1.00 38.21 C ATOM 262 C SER A 571 0.440 35.198 30.988 1.00 40.06 C ATOM 263 O SER A 571 1.277 34.431 31.432 1.00 41.25 O ATOM 264 CB SER A 571 1.487 37.440 31.025 1.00 37.06 C ATOM 265 OG SER A 571 0.619 37.749 32.092 1.00 38.21 O ATOM 266 N SER A 572 -0.868 35.054 31.203 1.00 42.95 N ATOM 267 CA SER A 572 -1.418 34.044 32.117 1.00 45.41 C ATOM 268 C SER A 572 -2.251 32.975 31.407 1.00 47.05 C ATOM 269 O SER A 572 -3.034 32.269 32.034 1.00 47.61 O ATOM 270 CB SER A 572 -2.254 34.721 33.218 1.00 45.21 C ATOM 271 OG SER A 572 -3.389 35.413 32.684 1.00 46.75 O ATOM 272 N SER A 573 -2.078 32.860 30.097 1.00 48.97 N ATOM 273 CA SER A 573 -2.841 31.921 29.299 1.00 51.00 C ATOM 274 C SER A 573 -1.977 31.497 28.123 1.00 52.25 C ATOM 275 O SER A 573 -0.988 32.164 27.805 1.00 52.61 O ATOM 276 CB SER A 573 -4.154 32.557 28.810 1.00 51.15 C ATOM 277 OG SER A 573 -3.925 33.757 28.064 1.00 52.55 O ATOM 278 N SER A 574 -2.319 30.369 27.510 1.00 53.46 N ATOM 279 CA SER A 574 -1.657 29.924 26.286 1.00 54.91 C ATOM 280 C SER A 574 -2.707 29.767 25.202 1.00 55.46 C ATOM 281 O SER A 574 -3.889 29.620 25.500 1.00 55.83 O ATOM 282 CB SER A 574 -0.891 28.611 26.509 1.00 55.04 C ATOM 283 OG SER A 574 -1.733 27.599 27.046 1.00 56.12 O ATOM 284 N ARG A 575 -2.279 29.801 23.949 1.00 56.28 N ATOM 285 CA ARG A 575 -3.199 29.771 22.818 1.00 56.90 C ATOM 286 C ARG A 575 -4.207 28.623 22.825 1.00 58.09 C ATOM 287 O ARG A 575 -5.309 28.765 22.296 1.00 58.19 O ATOM 288 CB ARG A 575 -2.428 29.787 21.504 1.00 56.83 C ATOM 289 CG ARG A 575 -1.566 31.006 21.337 1.00 55.25 C ATOM 290 CD ARG A 575 -1.343 31.314 19.880 1.00 53.80 C ATOM 291 NE ARG A 575 -0.534 32.521 19.726 1.00 53.41 N ATOM 292 CZ ARG A 575 -0.489 33.266 18.626 1.00 53.10 C ATOM 293 NH1 ARG A 575 -1.221 32.932 17.562 1.00 53.47 N ATOM 294 NH2 ARG A 575 0.282 34.351 18.592 1.00 51.71 N ATOM 295 N GLU A 576 -3.831 27.499 23.426 1.00 59.31 N ATOM 296 CA GLU A 576 -4.710 26.322 23.530 1.00 60.92 C ATOM 297 C GLU A 576 -5.827 26.516 24.570 1.00 59.98 C ATOM 298 O GLU A 576 -6.886 25.887 24.490 1.00 60.20 O ATOM 299 CB GLU A 576 -3.887 25.072 23.849 1.00 61.17 C ATOM 300 CG GLU A 576 -2.631 24.931 22.978 1.00 63.14 C ATOM 301 CD GLU A 576 -1.833 23.672 23.290 1.00 64.38 C ATOM 302 OE1 GLU A 576 -1.436 23.478 24.478 1.00 68.27 O ATOM 303 OE2 GLU A 576 -1.596 22.881 22.335 1.00 68.85 O ATOM 304 N GLN A 577 -5.583 27.400 25.534 1.00 58.97 N ATOM 305 CA GLN A 577 -6.605 27.809 26.497 1.00 58.09 C ATOM 306 C GLN A 577 -7.650 28.749 25.896 1.00 56.05 C ATOM 307 O GLN A 577 -8.738 28.878 26.453 1.00 56.02 O ATOM 308 CB GLN A 577 -5.969 28.503 27.706 1.00 58.34 C ATOM 309 CG GLN A 577 -4.869 27.720 28.411 1.00 59.62 C ATOM 310 CD GLN A 577 -4.289 28.482 29.597 1.00 60.30 C ATOM 311 OE1 GLN A 577 -4.947 29.358 30.176 1.00 63.29 O ATOM 312 NE2 GLN A 577 -3.054 28.146 29.972 1.00 62.87 N ATOM 313 N TRP A 578 -7.325 29.402 24.777 1.00 53.90 N ATOM 314 CA TRP A 578 -8.209 30.417 24.195 1.00 52.07 C ATOM 315 C TRP A 578 -9.519 29.820 23.692 1.00 52.43 C ATOM 316 O TRP A 578 -9.542 28.717 23.120 1.00 52.95 O ATOM 317 CB TRP A 578 -7.540 31.205 23.058 1.00 50.13 C ATOM 318 CG TRP A 578 -6.295 31.982 23.438 1.00 48.27 C ATOM 319 CD1 TRP A 578 -5.798 32.200 24.703 1.00 45.19 C ATOM 320 CD2 TRP A 578 -5.416 32.682 22.538 1.00 46.37 C ATOM 321 NE1 TRP A 578 -4.652 32.966 24.633 1.00 45.04 N ATOM 322 CE2 TRP A 578 -4.393 33.273 23.323 1.00 44.69 C ATOM 323 CE3 TRP A 578 -5.383 32.852 21.147 1.00 45.53 C ATOM 324 CZ2 TRP A 578 -3.355 34.020 22.763 1.00 45.94 C ATOM 325 CZ3 TRP A 578 -4.341 33.604 20.589 1.00 45.72 C ATOM 326 CH2 TRP A 578 -3.347 34.180 21.401 1.00 45.66 C ATOM 327 N THR A 579 -10.602 30.569 23.893 1.00 52.10 N ATOM 328 CA THR A 579 -11.946 30.099 23.579 1.00 51.62 C ATOM 329 C THR A 579 -12.361 30.588 22.199 1.00 51.51 C ATOM 330 O THR A 579 -12.531 31.788 21.995 1.00 50.57 O ATOM 331 CB THR A 579 -12.947 30.545 24.654 1.00 51.82 C ATOM 332 OG1 THR A 579 -12.522 30.036 25.925 1.00 51.44 O ATOM 333 CG2 THR A 579 -14.360 30.041 24.345 1.00 51.88 C ATOM 334 N PRO A 580 -12.501 29.649 21.230 1.00 51.75 N ATOM 335 CA PRO A 580 -12.954 30.077 19.917 1.00 51.76 C ATOM 336 C PRO A 580 -14.396 30.531 20.055 1.00 52.01 C ATOM 337 O PRO A 580 -15.171 29.946 20.828 1.00 52.00 O ATOM 338 CB PRO A 580 -12.851 28.804 19.068 1.00 51.74 C ATOM 339 CG PRO A 580 -12.930 27.687 20.046 1.00 52.07 C ATOM 340 CD PRO A 580 -12.256 28.193 21.290 1.00 51.66 C ATOM 341 N SER A 581 -14.750 31.574 19.327 1.00 52.08 N ATOM 342 CA SER A 581 -16.014 32.223 19.569 1.00 52.60 C ATOM 343 C SER A 581 -16.356 33.121 18.402 1.00 53.11 C ATOM 344 O SER A 581 -15.506 33.404 17.549 1.00 53.60 O ATOM 345 CB SER A 581 -15.939 33.059 20.865 1.00 52.42 C ATOM 346 OG SER A 581 -15.080 34.177 20.706 1.00 51.23 O ATOM 347 N HIS A 582 -17.598 33.594 18.386 1.00 53.35 N ATOM 348 CA HIS A 582 -18.001 34.629 17.436 1.00 53.51 C ATOM 349 C HIS A 582 -18.709 35.785 18.149 1.00 52.31 C ATOM 350 O HIS A 582 -19.362 35.587 19.177 1.00 52.31 O ATOM 351 CB HIS A 582 -18.851 34.029 16.296 1.00 54.23 C ATOM 352 CG HIS A 582 -19.712 32.888 16.730 1.00 57.52 C ATOM 353 ND1 HIS A 582 -21.078 32.997 16.871 1.00 61.13 N ATOM 354 CD2 HIS A 582 -19.398 31.618 17.083 1.00 60.70 C ATOM 355 CE1 HIS A 582 -21.570 31.842 17.287 1.00 61.64 C ATOM 356 NE2 HIS A 582 -20.571 30.988 17.427 1.00 61.13 N ATOM 357 N VAL A 583 -18.541 36.990 17.616 1.00 51.10 N ATOM 358 CA VAL A 583 -19.176 38.155 18.192 1.00 49.97 C ATOM 359 C VAL A 583 -20.299 38.603 17.280 1.00 49.39 C ATOM 360 O VAL A 583 -20.072 39.015 16.134 1.00 49.15 O ATOM 361 CB VAL A 583 -18.191 39.331 18.433 1.00 49.97 C ATOM 362 CG1 VAL A 583 -18.935 40.581 18.924 1.00 48.62 C ATOM 363 CG2 VAL A 583 -17.096 38.929 19.416 1.00 49.14 C ATOM 364 N SER A 584 -21.512 38.527 17.806 1.00 48.05 N ATOM 365 CA SER A 584 -22.650 39.048 17.092 1.00 47.33 C ATOM 366 C SER A 584 -22.831 40.513 17.441 1.00 46.53 C ATOM 367 O SER A 584 -22.950 40.886 18.607 1.00 45.72 O ATOM 368 CB SER A 584 -23.909 38.250 17.414 1.00 47.45 C ATOM 369 OG SER A 584 -24.990 38.787 16.689 1.00 48.48 O ATOM 370 N VAL A 585 -22.831 41.342 16.408 1.00 46.16 N ATOM 371 CA VAL A 585 -22.943 42.768 16.569 1.00 45.65 C ATOM 372 C VAL A 585 -24.371 43.117 16.168 1.00 46.22 C ATOM 373 O VAL A 585 -24.739 42.993 15.001 1.00 46.27 O ATOM 374 CB VAL A 585 -21.881 43.523 15.698 1.00 45.79 C ATOM 375 CG1 VAL A 585 -22.038 45.040 15.813 1.00 44.34 C ATOM 376 CG2 VAL A 585 -20.455 43.099 16.075 1.00 44.74 C ATOM 377 N ALA A 586 -25.187 43.497 17.149 1.00 46.23 N ATOM 378 CA ALA A 586 -26.552 43.934 16.886 1.00 45.93 C ATOM 379 C ALA A 586 -26.650 45.427 17.191 1.00 45.43 C ATOM 380 O ALA A 586 -25.688 46.012 17.724 1.00 45.96 O ATOM 381 CB ALA A 586 -27.560 43.119 17.703 1.00 46.27 C ATOM 382 N PRO A 587 -27.760 46.071 16.788 1.00 44.77 N ATOM 383 CA PRO A 587 -27.968 47.505 17.081 1.00 44.26 C ATOM 384 C PRO A 587 -27.699 47.947 18.531 1.00 43.12 C ATOM 385 O PRO A 587 -27.115 49.017 18.757 1.00 42.57 O ATOM 386 CB PRO A 587 -29.458 47.748 16.750 1.00 43.98 C ATOM 387 CG PRO A 587 -30.011 46.429 16.222 1.00 45.44 C ATOM 388 CD PRO A 587 -28.834 45.523 15.931 1.00 45.15 C ATOM 389 N ALA A 588 -28.155 47.147 19.491 1.00 41.59 N ATOM 390 CA ALA A 588 -28.185 47.588 20.876 1.00 40.49 C ATOM 391 C ALA A 588 -27.238 46.790 21.760 1.00 39.35 C ATOM 392 O ALA A 588 -26.954 47.193 22.880 1.00 38.51 O ATOM 393 CB ALA A 588 -29.615 47.507 21.414 1.00 40.48 C ATOM 394 N THR A 589 -26.756 45.662 21.247 1.00 39.09 N ATOM 395 CA THR A 589 -25.957 44.729 22.043 1.00 39.56 C ATOM 396 C THR A 589 -24.827 44.109 21.234 1.00 39.15 C ATOM 397 O THR A 589 -24.919 44.005 20.005 1.00 39.39 O ATOM 398 CB THR A 589 -26.813 43.551 22.605 1.00 39.97 C ATOM 399 OG1 THR A 589 -27.358 42.792 21.513 1.00 42.07 O ATOM 400 CG2 THR A 589 -27.960 44.039 23.516 1.00 39.33 C ATOM 401 N LEU A 590 -23.764 43.706 21.935 1.00 38.62 N ATOM 402 CA LEU A 590 -22.786 42.756 21.411 1.00 38.04 C ATOM 403 C LEU A 590 -22.989 41.454 22.172 1.00 38.23 C ATOM 404 O LEU A 590 -23.087 41.456 23.410 1.00 37.61 O ATOM 405 CB LEU A 590 -21.332 43.234 21.608 1.00 37.39 C ATOM 406 CG LEU A 590 -20.940 44.697 21.366 1.00 38.35 C ATOM 407 CD1 LEU A 590 -19.423 44.854 21.480 1.00 36.81 C ATOM 408 CD2 LEU A 590 -21.443 45.250 20.022 1.00 38.12 C ATOM 409 N THR A 591 -23.047 40.352 21.438 1.00 38.38 N ATOM 410 CA THR A 591 -23.143 39.048 22.061 1.00 40.18 C ATOM 411 C THR A 591 -21.945 38.207 21.643 1.00 41.23 C ATOM 412 O THR A 591 -21.635 38.105 20.459 1.00 41.38 O ATOM 413 CB THR A 591 -24.488 38.336 21.722 1.00 40.11 C ATOM 414 OG1 THR A 591 -25.573 39.241 21.980 1.00 40.14 O ATOM 415 CG2 THR A 591 -24.676 37.090 22.578 1.00 39.56 C ATOM 416 N ILE A 592 -21.274 37.638 22.637 1.00 43.04 N ATOM 417 CA ILE A 592 -20.141 36.740 22.426 1.00 45.76 C ATOM 418 C ILE A 592 -20.580 35.293 22.621 1.00 47.83 C ATOM 419 O ILE A 592 -21.066 34.922 23.684 1.00 47.79 O ATOM 420 CB ILE A 592 -18.942 37.053 23.391 1.00 45.62 C ATOM 421 CG1 ILE A 592 -18.692 38.575 23.504 1.00 44.87 C ATOM 422 CG2 ILE A 592 -17.701 36.303 22.925 1.00 44.82 C ATOM 423 CD1 ILE A 592 -17.956 38.999 24.766 1.00 45.07 C ATOM 424 N LEU A 593 -20.383 34.476 21.589 1.00 51.53 N ATOM 425 CA LEU A 593 -20.856 33.073 21.593 1.00 54.86 C ATOM 426 C LEU A 593 -19.737 32.070 21.252 1.00 56.64 C ATOM 427 O LEU A 593 -18.905 32.358 20.400 1.00 56.92 O ATOM 428 CB LEU A 593 -22.008 32.929 20.586 1.00 55.11 C ATOM 429 CG LEU A 593 -23.020 34.092 20.503 1.00 55.64 C ATOM 430 CD1 LEU A 593 -23.151 34.666 19.089 1.00 55.17 C ATOM 431 CD2 LEU A 593 -24.370 33.687 21.085 1.00 55.36 C ATOM 432 N HIS A 594 -19.734 30.909 21.911 1.00 59.64 N ATOM 433 CA HIS A 594 -18.795 29.790 21.618 1.00 62.47 C ATOM 434 C HIS A 594 -18.836 29.363 20.132 1.00 64.05 C ATOM 435 O HIS A 594 -19.915 29.400 19.513 1.00 64.16 O ATOM 436 CB HIS A 594 -19.119 28.604 22.518 1.00 62.47 C ATOM 437 CG HIS A 594 -17.915 27.943 23.120 1.00 64.47 C ATOM 438 ND1 HIS A 594 -16.936 27.332 22.362 1.00 65.46 N ATOM 439 CD2 HIS A 594 -17.549 27.773 24.416 1.00 65.61 C ATOM 440 CE1 HIS A 594 -16.012 26.829 23.165 1.00 65.84 C ATOM 441 NE2 HIS A 594 -16.360 27.083 24.416 1.00 65.53 N ATOM 442 N GLN A 595 -17.682 28.949 19.571 1.00 65.90 N ATOM 443 CA GLN A 595 -17.480 28.935 18.094 1.00 67.31 C ATOM 444 C GLN A 595 -18.582 28.378 17.201 1.00 68.11 C ATOM 445 O GLN A 595 -18.932 29.000 16.182 1.00 68.67 O ATOM 446 CB GLN A 595 -16.137 28.362 17.621 1.00 67.47 C ATOM 447 CG GLN A 595 -16.125 28.307 16.074 1.00 68.47 C ATOM 448 CD GLN A 595 -14.849 27.812 15.443 1.00 70.15 C ATOM 449 OE1 GLN A 595 -14.213 26.874 15.931 1.00 70.63 O ATOM 450 NE2 GLN A 595 -14.478 28.428 14.317 1.00 70.54 N ATOM 451 N GLN A 596 -19.103 27.195 17.515 1.00 68.88 N ATOM 452 CA GLN A 596 -20.258 26.763 16.735 1.00 69.47 C ATOM 453 C GLN A 596 -21.431 26.096 17.458 1.00 69.38 C ATOM 454 O GLN A 596 -22.525 25.945 16.873 1.00 69.59 O ATOM 455 CB GLN A 596 -19.854 26.059 15.383 1.00 69.89 C ATOM 456 CG GLN A 596 -19.567 24.522 15.458 1.00 71.70 C ATOM 457 CD GLN A 596 -20.287 23.862 14.237 1.00 74.38 C ATOM 458 OE1 GLN A 596 -20.469 24.488 13.165 1.00 74.81 O ATOM 459 NE2 GLN A 596 -20.718 22.594 14.406 1.00 75.27 N ATOM 460 N THR A 597 -21.212 25.750 18.733 1.00 69.13 N ATOM 461 CA THR A 597 -22.318 25.479 19.666 1.00 68.61 C ATOM 462 C THR A 597 -23.185 26.746 19.824 1.00 68.03 C ATOM 463 O THR A 597 -24.392 26.667 20.093 1.00 68.22 O ATOM 464 CB THR A 597 -21.818 25.010 21.060 1.00 68.71 C ATOM 465 OG1 THR A 597 -21.072 26.063 21.694 1.00 69.68 O ATOM 466 CG2 THR A 597 -20.940 23.780 20.940 1.00 68.40 C ATOM 467 N GLU A 598 -22.549 27.905 19.632 1.00 67.01 N ATOM 468 CA GLU A 598 -23.190 29.228 19.702 1.00 66.05 C ATOM 469 C GLU A 598 -23.831 29.559 21.065 1.00 64.83 C ATOM 470 O GLU A 598 -24.714 30.423 21.144 1.00 64.99 O ATOM 471 CB GLU A 598 -24.168 29.448 18.535 1.00 66.46 C ATOM 472 CG GLU A 598 -23.566 29.178 17.144 1.00 68.68 C ATOM 473 CD GLU A 598 -23.984 30.211 16.085 1.00 71.36 C ATOM 474 OE1 GLU A 598 -25.018 30.885 16.283 1.00 72.82 O ATOM 475 OE2 GLU A 598 -23.274 30.355 15.056 1.00 71.83 O ATOM 476 N ALA A 599 -23.377 28.869 22.119 1.00 63.01 N ATOM 477 CA ALA A 599 -23.690 29.198 23.514 1.00 61.39 C ATOM 478 C ALA A 599 -23.169 30.601 23.885 1.00 60.46 C ATOM 479 O ALA A 599 -22.130 31.046 23.372 1.00 60.20 O ATOM 480 CB ALA A 599 -23.089 28.166 24.436 1.00 61.38 C ATOM 481 N VAL A 600 -23.882 31.284 24.785 1.00 58.75 N ATOM 482 CA VAL A 600 -23.605 32.702 25.090 1.00 56.46 C ATOM 483 C VAL A 600 -22.531 32.871 26.173 1.00 54.73 C ATOM 484 O VAL A 600 -22.720 32.456 27.319 1.00 55.01 O ATOM 485 CB VAL A 600 -24.906 33.470 25.476 1.00 56.52 C ATOM 486 CG1 VAL A 600 -24.599 34.905 25.936 1.00 55.85 C ATOM 487 CG2 VAL A 600 -25.880 33.475 24.307 1.00 56.52 C ATOM 488 N LEU A 601 -21.421 33.503 25.793 1.00 52.14 N ATOM 489 CA LEU A 601 -20.283 33.744 26.694 1.00 49.71 C ATOM 490 C LEU A 601 -20.306 35.139 27.326 1.00 47.55 C ATOM 491 O LEU A 601 -19.674 35.362 28.359 1.00 47.03 O ATOM 492 CB LEU A 601 -18.954 33.579 25.932 1.00 49.78 C ATOM 493 CG LEU A 601 -18.605 32.227 25.309 1.00 50.22 C ATOM 494 CD1 LEU A 601 -17.494 32.404 24.283 1.00 49.94 C ATOM 495 CD2 LEU A 601 -18.198 31.228 26.385 1.00 52.06 C ATOM 496 N GLY A 602 -20.988 36.074 26.664 1.00 44.71 N ATOM 497 CA GLY A 602 -21.212 37.410 27.204 1.00 42.39 C ATOM 498 C GLY A 602 -22.203 38.163 26.352 1.00 40.35 C ATOM 499 O GLY A 602 -22.343 37.888 25.159 1.00 40.34 O ATOM 500 N GLU A 603 -22.916 39.099 26.968 1.00 38.75 N ATOM 501 CA GLU A 603 -23.787 40.015 26.229 1.00 37.72 C ATOM 502 C GLU A 603 -23.605 41.407 26.825 1.00 36.10 C ATOM 503 O GLU A 603 -23.516 41.555 28.039 1.00 36.82 O ATOM 504 CB GLU A 603 -25.266 39.556 26.245 1.00 37.69 C ATOM 505 CG GLU A 603 -26.163 40.253 25.173 1.00 38.85 C ATOM 506 CD GLU A 603 -27.439 39.455 24.804 1.00 40.53 C ATOM 507 OE1 GLU A 603 -27.613 38.283 25.240 1.00 43.32 O ATOM 508 OE2 GLU A 603 -28.269 40.007 24.047 1.00 44.38 O ATOM 509 N CYS A 604 -23.540 42.419 25.971 1.00 33.65 N ATOM 510 CA CYS A 604 -23.101 43.745 26.382 1.00 31.95 C ATOM 511 C CYS A 604 -23.918 44.785 25.647 1.00 30.39 C ATOM 512 O CYS A 604 -23.944 44.785 24.429 1.00 29.50 O ATOM 513 CB CYS A 604 -21.603 43.944 26.032 1.00 31.89 C ATOM 514 SG CYS A 604 -20.431 42.852 26.867 1.00 32.03 S ATOM 515 N ARG A 605 -24.558 45.669 26.401 1.00 29.23 N ATOM 516 CA ARG A 605 -25.288 46.784 25.852 1.00 29.99 C ATOM 517 C ARG A 605 -24.325 47.864 25.376 1.00 29.69 C ATOM 518 O ARG A 605 -23.495 48.327 26.139 1.00 29.12 O ATOM 519 CB ARG A 605 -26.229 47.399 26.898 1.00 29.33 C ATOM 520 CG ARG A 605 -27.579 46.686 27.004 1.00 30.53 C ATOM 521 CD ARG A 605 -28.487 47.267 28.088 1.00 30.34 C ATOM 522 NE ARG A 605 -29.635 46.348 28.290 1.00 34.53 N ATOM 523 CZ ARG A 605 -30.792 46.429 27.629 1.00 37.09 C ATOM 524 NH1 ARG A 605 -31.010 47.398 26.724 1.00 35.96 N ATOM 525 NH2 ARG A 605 -31.741 45.538 27.864 1.00 35.84 N ATOM 526 N VAL A 606 -24.499 48.274 24.124 1.00 30.60 N ATOM 527 CA VAL A 606 -23.722 49.343 23.485 1.00 30.63 C ATOM 528 C VAL A 606 -23.720 50.628 24.336 1.00 31.49 C ATOM 529 O VAL A 606 -22.681 51.271 24.521 1.00 31.35 O ATOM 530 CB VAL A 606 -24.237 49.567 22.030 1.00 30.68 C ATOM 531 CG1 VAL A 606 -23.529 50.745 21.332 1.00 30.24 C ATOM 532 CG2 VAL A 606 -24.088 48.294 21.213 1.00 30.76 C ATOM 533 N ARG A 607 -24.860 50.990 24.921 1.00 31.22 N ATOM 534 CA ARG A 607 -24.886 52.178 25.779 1.00 31.97 C ATOM 535 C ARG A 607 -23.949 52.125 26.997 1.00 31.14 C ATOM 536 O ARG A 607 -23.594 53.180 27.541 1.00 31.98 O ATOM 537 CB ARG A 607 -26.331 52.478 26.238 1.00 33.01 C ATOM 538 CG ARG A 607 -26.827 51.535 27.323 1.00 35.91 C ATOM 539 CD ARG A 607 -28.316 51.741 27.530 1.00 43.97 C ATOM 540 NE ARG A 607 -28.609 52.904 28.359 1.00 48.01 N ATOM 541 CZ ARG A 607 -29.830 53.428 28.500 1.00 51.07 C ATOM 542 NH1 ARG A 607 -30.874 52.906 27.843 1.00 48.98 N ATOM 543 NH2 ARG A 607 -30.005 54.477 29.301 1.00 51.01 N ATOM 544 N PHE A 608 -23.552 50.920 27.447 1.00 30.09 N ATOM 545 CA PHE A 608 -22.649 50.831 28.582 1.00 28.86 C ATOM 546 C PHE A 608 -21.207 50.469 28.188 1.00 28.41 C ATOM 547 O PHE A 608 -20.355 50.252 29.049 1.00 27.33 O ATOM 548 CB PHE A 608 -23.189 49.894 29.671 1.00 29.49 C ATOM 549 CG PHE A 608 -24.473 50.383 30.298 1.00 30.60 C ATOM 550 CD1 PHE A 608 -24.525 51.619 30.932 1.00 31.13 C ATOM 551 CD2 PHE A 608 -25.630 49.600 30.243 1.00 32.92 C ATOM 552 CE1 PHE A 608 -25.722 52.101 31.504 1.00 33.70 C ATOM 553 CE2 PHE A 608 -26.841 50.055 30.815 1.00 32.75 C ATOM 554 CZ PHE A 608 -26.888 51.310 31.439 1.00 33.23 C ATOM 555 N LEU A 609 -20.959 50.406 26.884 1.00 27.47 N ATOM 556 CA LEU A 609 -19.605 50.245 26.372 1.00 28.08 C ATOM 557 C LEU A 609 -18.979 51.624 26.387 1.00 27.46 C ATOM 558 O LEU A 609 -19.428 52.516 25.691 1.00 28.23 O ATOM 559 CB LEU A 609 -19.637 49.618 24.969 1.00 27.97 C ATOM 560 CG LEU A 609 -18.297 49.131 24.356 1.00 27.52 C ATOM 561 CD1 LEU A 609 -18.573 48.167 23.226 1.00 28.80 C ATOM 562 CD2 LEU A 609 -17.487 50.310 23.861 1.00 26.25 C ATOM 563 N SER A 610 -17.985 51.831 27.236 1.00 27.62 N ATOM 564 CA SER A 610 -17.388 53.154 27.352 1.00 27.46 C ATOM 565 C SER A 610 -16.254 53.394 26.326 1.00 27.66 C ATOM 566 O SER A 610 -16.032 54.521 25.895 1.00 27.61 O ATOM 567 CB SER A 610 -16.876 53.380 28.765 1.00 26.84 C ATOM 568 OG SER A 610 -16.185 52.243 29.211 1.00 28.05 O ATOM 569 N PHE A 611 -15.543 52.338 25.942 1.00 28.24 N ATOM 570 CA PHE A 611 -14.300 52.507 25.139 1.00 28.18 C ATOM 571 C PHE A 611 -13.979 51.242 24.398 1.00 27.97 C ATOM 572 O PHE A 611 -14.269 50.145 24.871 1.00 28.38 O ATOM 573 CB PHE A 611 -13.131 52.865 26.077 1.00 28.20 C ATOM 574 CG PHE A 611 -11.818 53.151 25.384 1.00 28.78 C ATOM 575 CD1 PHE A 611 -11.586 54.394 24.785 1.00 28.21 C ATOM 576 CD2 PHE A 611 -10.807 52.199 25.372 1.00 28.02 C ATOM 577 CE1 PHE A 611 -10.364 54.676 24.173 1.00 30.35 C ATOM 578 CE2 PHE A 611 -9.573 52.465 24.761 1.00 28.45 C ATOM 579 CZ PHE A 611 -9.358 53.708 24.165 1.00 28.77 C ATOM 580 N LEU A 612 -13.373 51.383 23.229 1.00 27.84 N ATOM 581 CA LEU A 612 -12.849 50.235 22.514 1.00 27.70 C ATOM 582 C LEU A 612 -11.525 50.602 21.852 1.00 28.49 C ATOM 583 O LEU A 612 -11.230 51.802 21.618 1.00 27.56 O ATOM 584 CB LEU A 612 -13.848 49.726 21.474 1.00 28.51 C ATOM 585 CG LEU A 612 -14.239 50.736 20.384 1.00 30.11 C ATOM 586 CD1 LEU A 612 -13.434 50.459 19.087 1.00 33.46 C ATOM 587 CD2 LEU A 612 -15.691 50.673 20.102 1.00 32.82 C ATOM 588 N ALA A 613 -10.730 49.575 21.556 1.00 28.35 N ATOM 589 CA ALA A 613 -9.451 49.789 20.872 1.00 28.75 C ATOM 590 C ALA A 613 -8.882 48.541 20.302 1.00 28.56 C ATOM 591 O ALA A 613 -9.247 47.434 20.683 1.00 28.13 O ATOM 592 CB ALA A 613 -8.413 50.443 21.791 1.00 27.94 C ATOM 593 N VAL A 614 -7.953 48.731 19.374 1.00 28.96 N ATOM 594 CA VAL A 614 -7.135 47.640 18.915 1.00 29.19 C ATOM 595 C VAL A 614 -5.863 47.796 19.751 1.00 28.74 C ATOM 596 O VAL A 614 -5.455 48.920 20.025 1.00 28.56 O ATOM 597 CB VAL A 614 -6.881 47.722 17.372 1.00 29.99 C ATOM 598 CG1 VAL A 614 -5.784 46.759 16.951 1.00 28.41 C ATOM 599 CG2 VAL A 614 -8.186 47.375 16.603 1.00 29.96 C ATOM 600 N GLY A 615 -5.274 46.687 20.200 1.00 28.53 N ATOM 601 CA GLY A 615 -4.081 46.774 21.055 1.00 29.65 C ATOM 602 C GLY A 615 -2.835 47.036 20.204 1.00 30.44 C ATOM 603 O GLY A 615 -2.934 47.097 18.978 1.00 30.76 O ATOM 604 N ARG A 616 -1.673 47.186 20.840 1.00 30.40 N ATOM 605 CA ARG A 616 -0.433 47.456 20.110 1.00 30.95 C ATOM 606 C ARG A 616 -0.102 46.320 19.172 1.00 31.50 C ATOM 607 O ARG A 616 0.407 46.553 18.097 1.00 32.79 O ATOM 608 CB ARG A 616 0.732 47.749 21.058 1.00 30.88 C ATOM 609 CG ARG A 616 0.492 48.922 21.948 1.00 30.13 C ATOM 610 CD ARG A 616 0.195 50.209 21.179 1.00 29.33 C ATOM 611 NE ARG A 616 0.078 51.324 22.110 1.00 29.83 N ATOM 612 CZ ARG A 616 -0.232 52.567 21.770 1.00 33.27 C ATOM 613 NH1 ARG A 616 -0.489 52.864 20.505 1.00 33.66 N ATOM 614 NH2 ARG A 616 -0.320 53.511 22.701 1.00 33.73 N ATOM 615 N ASP A 617 -0.427 45.102 19.564 1.00 31.76 N ATOM 616 CA ASP A 617 -0.450 43.998 18.638 1.00 33.46 C ATOM 617 C ASP A 617 -1.798 43.994 17.889 1.00 33.59 C ATOM 618 O ASP A 617 -2.875 43.906 18.502 1.00 31.75 O ATOM 619 CB ASP A 617 -0.242 42.672 19.353 1.00 33.40 C ATOM 620 CG ASP A 617 -0.131 41.508 18.397 1.00 37.00 C ATOM 621 OD1 ASP A 617 -1.018 41.345 17.548 1.00 36.91 O ATOM 622 OD2 ASP A 617 0.848 40.722 18.503 1.00 41.81 O ATOM 623 N VAL A 618 -1.686 44.053 16.560 1.00 33.40 N ATOM 624 CA VAL A 618 -2.794 44.315 15.638 1.00 34.31 C ATOM 625 C VAL A 618 -3.874 43.229 15.673 1.00 33.73 C ATOM 626 O VAL A 618 -4.978 43.426 15.200 1.00 34.57 O ATOM 627 CB VAL A 618 -2.235 44.538 14.191 1.00 34.51 C ATOM 628 CG1 VAL A 618 -1.878 43.204 13.534 1.00 33.81 C ATOM 629 CG2 VAL A 618 -3.216 45.298 13.362 1.00 37.28 C ATOM 630 N HIS A 619 -3.547 42.081 16.236 1.00 33.90 N ATOM 631 CA HIS A 619 -4.514 40.999 16.418 1.00 34.73 C ATOM 632 C HIS A 619 -5.497 41.219 17.575 1.00 33.76 C ATOM 633 O HIS A 619 -6.546 40.576 17.648 1.00 33.94 O ATOM 634 CB HIS A 619 -3.775 39.711 16.723 1.00 35.52 C ATOM 635 CG HIS A 619 -2.843 39.265 15.640 1.00 37.50 C ATOM 636 ND1 HIS A 619 -1.558 39.747 15.521 1.00 38.98 N ATOM 637 CD2 HIS A 619 -3.003 38.360 14.649 1.00 38.81 C ATOM 638 CE1 HIS A 619 -0.972 39.171 14.489 1.00 40.16 C ATOM 639 NE2 HIS A 619 -1.824 38.319 13.948 1.00 41.17 N ATOM 640 N THR A 620 -5.143 42.096 18.494 1.00 33.08 N ATOM 641 CA THR A 620 -5.883 42.154 19.746 1.00 32.76 C ATOM 642 C THR A 620 -6.990 43.200 19.675 1.00 31.96 C ATOM 643 O THR A 620 -6.774 44.319 19.194 1.00 32.10 O ATOM 644 CB THR A 620 -4.977 42.468 20.964 1.00 31.93 C ATOM 645 OG1 THR A 620 -4.336 43.725 20.771 1.00 31.98 O ATOM 646 CG2 THR A 620 -3.938 41.362 21.214 1.00 32.36 C ATOM 647 N PHE A 621 -8.157 42.827 20.175 1.00 30.97 N ATOM 648 CA PHE A 621 -9.236 43.799 20.364 1.00 30.26 C ATOM 649 C PHE A 621 -9.739 43.810 21.830 1.00 28.60 C ATOM 650 O PHE A 621 -9.841 42.765 22.449 1.00 28.63 O ATOM 651 CB PHE A 621 -10.362 43.502 19.360 1.00 29.67 C ATOM 652 CG PHE A 621 -11.559 44.418 19.488 1.00 30.49 C ATOM 653 CD1 PHE A 621 -11.459 45.781 19.176 1.00 33.08 C ATOM 654 CD2 PHE A 621 -12.775 43.921 19.927 1.00 30.88 C ATOM 655 CE1 PHE A 621 -12.577 46.645 19.298 1.00 33.66 C ATOM 656 CE2 PHE A 621 -13.892 44.775 20.057 1.00 29.92 C ATOM 657 CZ PHE A 621 -13.786 46.132 19.735 1.00 29.48 C ATOM 658 N ALA A 622 -10.041 44.987 22.370 1.00 28.14 N ATOM 659 CA ALA A 622 -10.683 45.084 23.697 1.00 28.12 C ATOM 660 C ALA A 622 -11.729 46.173 23.748 1.00 27.39 C ATOM 661 O ALA A 622 -11.629 47.193 23.065 1.00 27.85 O ATOM 662 CB ALA A 622 -9.615 45.310 24.827 1.00 27.24 C ATOM 663 N PHE A 623 -12.747 45.963 24.563 1.00 27.00 N ATOM 664 CA PHE A 623 -13.650 47.056 24.890 1.00 26.45 C ATOM 665 C PHE A 623 -13.872 47.075 26.381 1.00 25.63 C ATOM 666 O PHE A 623 -13.797 46.040 27.043 1.00 25.65 O ATOM 667 CB PHE A 623 -14.979 47.002 24.090 1.00 26.06 C ATOM 668 CG PHE A 623 -15.796 45.751 24.312 1.00 28.41 C ATOM 669 CD1 PHE A 623 -16.728 45.677 25.353 1.00 27.12 C ATOM 670 CD2 PHE A 623 -15.669 44.664 23.444 1.00 27.63 C ATOM 671 CE1 PHE A 623 -17.510 44.508 25.543 1.00 30.38 C ATOM 672 CE2 PHE A 623 -16.430 43.519 23.620 1.00 28.49 C ATOM 673 CZ PHE A 623 -17.355 43.435 24.677 1.00 28.05 C ATOM 674 N ILE A 624 -14.121 48.258 26.908 1.00 25.38 N ATOM 675 CA ILE A 624 -14.407 48.410 28.322 1.00 25.47 C ATOM 676 C ILE A 624 -15.908 48.641 28.481 1.00 25.79 C ATOM 677 O ILE A 624 -16.502 49.448 27.786 1.00 25.32 O ATOM 678 CB ILE A 624 -13.603 49.570 28.948 1.00 25.41 C ATOM 679 CG1 ILE A 624 -12.094 49.316 28.763 1.00 24.63 C ATOM 680 CG2 ILE A 624 -13.961 49.793 30.456 1.00 23.35 C ATOM 681 CD1 ILE A 624 -11.197 50.544 29.213 1.00 25.99 C ATOM 682 N MET A 625 -16.498 47.891 29.394 1.00 26.45 N ATOM 683 CA MET A 625 -17.906 48.056 29.766 1.00 26.60 C ATOM 684 C MET A 625 -18.020 48.716 31.117 1.00 26.63 C ATOM 685 O MET A 625 -17.264 48.409 32.005 1.00 26.86 O ATOM 686 CB MET A 625 -18.554 46.678 29.842 1.00 27.03 C ATOM 687 CG MET A 625 -18.755 45.984 28.467 1.00 25.49 C ATOM 688 SD MET A 625 -19.878 46.848 27.351 1.00 30.31 S ATOM 689 CE MET A 625 -21.422 46.821 28.279 1.00 29.57 C ATOM 690 N ALA A 626 -18.958 49.636 31.285 1.00 27.70 N ATOM 691 CA ALA A 626 -19.329 50.039 32.628 1.00 29.34 C ATOM 692 C ALA A 626 -20.324 48.985 33.142 1.00 30.86 C ATOM 693 O ALA A 626 -21.538 49.091 32.886 1.00 31.60 O ATOM 694 CB ALA A 626 -19.952 51.407 32.607 1.00 28.58 C ATOM 695 N ALA A 627 -19.793 47.970 33.822 1.00 32.41 N ATOM 696 CA ALA A 627 -20.588 46.875 34.442 1.00 33.84 C ATOM 697 C ALA A 627 -21.588 47.387 35.480 1.00 34.95 C ATOM 698 O ALA A 627 -22.695 46.850 35.605 1.00 34.88 O ATOM 699 CB ALA A 627 -19.676 45.844 35.071 1.00 33.58 C ATOM 700 N GLY A 628 -21.166 48.417 36.213 1.00 36.05 N ATOM 701 CA GLY A 628 -22.013 49.200 37.103 1.00 37.83 C ATOM 702 C GLY A 628 -21.566 50.657 37.068 1.00 39.37 C ATOM 703 O GLY A 628 -20.645 50.996 36.325 1.00 39.01 O ATOM 704 N PRO A 629 -22.244 51.538 37.838 1.00 40.51 N ATOM 705 CA PRO A 629 -21.924 52.966 37.925 1.00 41.46 C ATOM 706 C PRO A 629 -20.446 53.242 38.193 1.00 41.92 C ATOM 707 O PRO A 629 -19.879 54.173 37.611 1.00 43.23 O ATOM 708 CB PRO A 629 -22.784 53.443 39.099 1.00 41.66 C ATOM 709 CG PRO A 629 -23.994 52.555 39.012 1.00 41.75 C ATOM 710 CD PRO A 629 -23.428 51.203 38.655 1.00 41.10 C ATOM 711 N ALA A 630 -19.806 52.433 39.031 1.00 41.70 N ATOM 712 CA ALA A 630 -18.383 52.680 39.321 1.00 40.74 C ATOM 713 C ALA A 630 -17.540 51.432 39.107 1.00 39.58 C ATOM 714 O ALA A 630 -16.569 51.205 39.826 1.00 39.24 O ATOM 715 CB ALA A 630 -18.222 53.200 40.754 1.00 41.41 C ATOM 716 N SER A 631 -17.926 50.626 38.124 1.00 37.79 N ATOM 717 CA SER A 631 -17.320 49.321 37.946 1.00 36.77 C ATOM 718 C SER A 631 -17.054 49.042 36.468 1.00 35.04 C ATOM 719 O SER A 631 -17.979 49.020 35.660 1.00 34.72 O ATOM 720 CB SER A 631 -18.253 48.259 38.547 1.00 37.01 C ATOM 721 OG SER A 631 -17.521 47.129 38.975 1.00 39.61 O ATOM 722 N PHE A 632 -15.789 48.822 36.118 1.00 33.25 N ATOM 723 CA PHE A 632 -15.419 48.627 34.714 1.00 31.45 C ATOM 724 C PHE A 632 -14.837 47.262 34.441 1.00 30.88 C ATOM 725 O PHE A 632 -14.049 46.742 35.217 1.00 30.19 O ATOM 726 CB PHE A 632 -14.500 49.761 34.215 1.00 31.01 C ATOM 727 CG PHE A 632 -15.077 51.118 34.465 1.00 30.52 C ATOM 728 CD1 PHE A 632 -16.112 51.598 33.673 1.00 29.73 C ATOM 729 CD2 PHE A 632 -14.648 51.884 35.552 1.00 31.32 C ATOM 730 CE1 PHE A 632 -16.685 52.842 33.927 1.00 31.92 C ATOM 731 CE2 PHE A 632 -15.212 53.119 35.825 1.00 31.57 C ATOM 732 CZ PHE A 632 -16.236 53.613 35.017 1.00 30.96 C ATOM 733 N CYS A 633 -15.238 46.701 33.312 1.00 30.46 N ATOM 734 CA CYS A 633 -14.811 45.377 32.919 1.00 30.74 C ATOM 735 C CYS A 633 -14.234 45.433 31.505 1.00 29.19 C ATOM 736 O CYS A 633 -14.858 45.971 30.618 1.00 30.33 O ATOM 737 CB CYS A 633 -16.050 44.440 32.959 1.00 29.64 C ATOM 738 SG CYS A 633 -15.745 42.754 32.507 1.00 33.94 S ATOM 739 N CYS A 634 -13.066 44.856 31.293 1.00 28.29 N ATOM 740 CA CYS A 634 -12.456 44.840 29.951 1.00 27.17 C ATOM 741 C CYS A 634 -12.563 43.467 29.262 1.00 26.48 C ATOM 742 O CYS A 634 -12.050 42.487 29.766 1.00 26.42 O ATOM 743 CB CYS A 634 -11.002 45.266 30.045 1.00 27.33 C ATOM 744 SG CYS A 634 -10.205 45.416 28.425 1.00 26.69 S ATOM 745 N HIS A 635 -13.249 43.412 28.119 1.00 25.87 N ATOM 746 CA HIS A 635 -13.421 42.176 27.351 1.00 26.81 C ATOM 747 C HIS A 635 -12.410 42.110 26.217 1.00 27.15 C ATOM 748 O HIS A 635 -12.272 43.070 25.483 1.00 26.58 O ATOM 749 CB HIS A 635 -14.836 42.117 26.771 1.00 27.11 C ATOM 750 CG HIS A 635 -15.907 42.021 27.823 1.00 26.94 C ATOM 751 ND1 HIS A 635 -16.504 40.829 28.173 1.00 28.99 N ATOM 752 CD2 HIS A 635 -16.475 42.969 28.601 1.00 27.56 C ATOM 753 CE1 HIS A 635 -17.395 41.047 29.123 1.00 29.70 C ATOM 754 NE2 HIS A 635 -17.409 42.342 29.392 1.00 29.08 N ATOM 755 N MET A 636 -11.724 40.980 26.066 1.00 28.35 N ATOM 756 CA MET A 636 -10.543 40.928 25.177 1.00 29.62 C ATOM 757 C MET A 636 -10.591 39.796 24.174 1.00 29.74 C ATOM 758 O MET A 636 -11.132 38.743 24.474 1.00 30.53 O ATOM 759 CB MET A 636 -9.278 40.841 26.024 1.00 29.24 C ATOM 760 CG MET A 636 -8.979 42.131 26.738 1.00 29.33 C ATOM 761 SD MET A 636 -7.884 41.963 28.164 1.00 31.19 S ATOM 762 CE MET A 636 -8.773 40.883 29.275 1.00 27.06 C ATOM 763 N PHE A 637 -10.038 40.031 22.983 1.00 30.44 N ATOM 764 CA PHE A 637 -10.127 39.078 21.870 1.00 31.47 C ATOM 765 C PHE A 637 -8.816 38.999 21.082 1.00 32.19 C ATOM 766 O PHE A 637 -8.081 39.976 20.993 1.00 31.58 O ATOM 767 CB PHE A 637 -11.257 39.486 20.883 1.00 31.61 C ATOM 768 CG PHE A 637 -12.611 39.667 21.536 1.00 31.86 C ATOM 769 CD1 PHE A 637 -12.939 40.871 22.144 1.00 28.50 C ATOM 770 CD2 PHE A 637 -13.552 38.624 21.535 1.00 32.20 C ATOM 771 CE1 PHE A 637 -14.179 41.047 22.774 1.00 30.24 C ATOM 772 CE2 PHE A 637 -14.801 38.786 22.163 1.00 31.33 C ATOM 773 CZ PHE A 637 -15.112 40.008 22.771 1.00 30.92 C ATOM 774 N TRP A 638 -8.546 37.826 20.512 1.00 33.61 N ATOM 775 CA TRP A 638 -7.476 37.668 19.529 1.00 34.73 C ATOM 776 C TRP A 638 -8.122 37.405 18.169 1.00 34.91 C ATOM 777 O TRP A 638 -8.939 36.495 18.014 1.00 35.93 O ATOM 778 CB TRP A 638 -6.547 36.512 19.908 1.00 34.99 C ATOM 779 CG TRP A 638 -5.352 36.403 18.991 1.00 35.06 C ATOM 780 CD1 TRP A 638 -5.290 35.734 17.805 1.00 35.04 C ATOM 781 CD2 TRP A 638 -4.061 36.995 19.186 1.00 36.08 C ATOM 782 NE1 TRP A 638 -4.037 35.868 17.241 1.00 35.85 N ATOM 783 CE2 TRP A 638 -3.263 36.642 18.065 1.00 36.07 C ATOM 784 CE3 TRP A 638 -3.504 37.806 20.184 1.00 36.27 C ATOM 785 CZ2 TRP A 638 -1.924 37.057 17.929 1.00 35.30 C ATOM 786 CZ3 TRP A 638 -2.172 38.219 20.044 1.00 35.11 C ATOM 787 CH2 TRP A 638 -1.406 37.847 18.915 1.00 35.16 C ATOM 788 N CYS A 639 -7.788 38.227 17.197 1.00 35.79 N ATOM 789 CA CYS A 639 -8.434 38.156 15.898 1.00 37.13 C ATOM 790 C CYS A 639 -7.431 37.866 14.780 1.00 37.98 C ATOM 791 O CYS A 639 -6.371 38.468 14.721 1.00 38.44 O ATOM 792 CB CYS A 639 -9.174 39.457 15.606 1.00 36.48 C ATOM 793 SG CYS A 639 -10.212 40.086 16.954 1.00 35.98 S ATOM 794 N GLU A 640 -7.808 36.962 13.885 1.00 39.92 N ATOM 795 CA GLU A 640 -6.999 36.611 12.712 1.00 40.98 C ATOM 796 C GLU A 640 -7.758 36.991 11.441 1.00 41.43 C ATOM 797 O GLU A 640 -8.938 36.663 11.319 1.00 41.74 O ATOM 798 CB GLU A 640 -6.716 35.111 12.694 1.00 41.22 C ATOM 799 CG GLU A 640 -5.869 34.600 13.851 1.00 42.98 C ATOM 800 CD GLU A 640 -4.404 34.954 13.714 1.00 45.42 C ATOM 801 OE1 GLU A 640 -4.006 35.480 12.645 1.00 46.78 O ATOM 802 OE2 GLU A 640 -3.647 34.698 14.680 1.00 46.31 O ATOM 803 N PRO A 641 -7.088 37.664 10.481 1.00 41.71 N ATOM 804 CA PRO A 641 -5.655 37.989 10.441 1.00 41.18 C ATOM 805 C PRO A 641 -5.280 39.164 11.333 1.00 40.56 C ATOM 806 O PRO A 641 -4.110 39.336 11.683 1.00 40.51 O ATOM 807 CB PRO A 641 -5.428 38.351 8.972 1.00 41.65 C ATOM 808 CG PRO A 641 -6.751 38.900 8.508 1.00 42.03 C ATOM 809 CD PRO A 641 -7.810 38.183 9.298 1.00 41.93 C ATOM 810 N ASN A 642 -6.280 39.979 11.664 1.00 39.76 N ATOM 811 CA ASN A 642 -6.141 41.096 12.585 1.00 38.25 C ATOM 812 C ASN A 642 -7.526 41.468 13.118 1.00 37.32 C ATOM 813 O ASN A 642 -8.536 40.835 12.752 1.00 37.12 O ATOM 814 CB ASN A 642 -5.452 42.299 11.926 1.00 38.08 C ATOM 815 CG ASN A 642 -6.189 42.794 10.687 1.00 40.53 C ATOM 816 OD1 ASN A 642 -7.410 43.000 10.708 1.00 42.71 O ATOM 817 ND2 ASN A 642 -5.451 42.970 9.593 1.00 40.99 N ATOM 818 N ALA A 643 -7.564 42.503 13.953 1.00 35.93 N ATOM 819 CA ALA A 643 -8.797 42.941 14.609 1.00 35.60 C ATOM 820 C ALA A 643 -9.565 44.016 13.813 1.00 34.98 C ATOM 821 O ALA A 643 -10.487 44.639 14.357 1.00 35.16 O ATOM 822 CB ALA A 643 -8.478 43.446 16.032 1.00 34.13 C ATOM 823 N ALA A 644 -9.175 44.271 12.555 1.00 34.10 N ATOM 824 CA ALA A 644 -9.760 45.404 11.851 1.00 33.92 C ATOM 825 C ALA A 644 -11.273 45.239 11.692 1.00 33.76 C ATOM 826 O ALA A 644 -12.022 46.111 12.114 1.00 33.79 O ATOM 827 CB ALA A 644 -9.054 45.731 10.493 1.00 34.19 C ATOM 828 N SER A 645 -11.730 44.117 11.169 1.00 34.34 N ATOM 829 CA SER A 645 -13.166 43.989 10.914 1.00 35.29 C ATOM 830 C SER A 645 -14.038 44.025 12.190 1.00 34.60 C ATOM 831 O SER A 645 -15.080 44.667 12.194 1.00 33.43 O ATOM 832 CB SER A 645 -13.484 42.808 10.007 1.00 35.52 C ATOM 833 OG SER A 645 -13.377 41.591 10.695 1.00 41.42 O ATOM 834 N LEU A 646 -13.574 43.401 13.277 1.00 33.91 N ATOM 835 CA LEU A 646 -14.325 43.394 14.535 1.00 32.90 C ATOM 836 C LEU A 646 -14.402 44.772 15.144 1.00 33.28 C ATOM 837 O LEU A 646 -15.490 45.222 15.520 1.00 33.40 O ATOM 838 CB LEU A 646 -13.746 42.387 15.549 1.00 33.22 C ATOM 839 CG LEU A 646 -14.422 42.257 16.933 1.00 32.99 C ATOM 840 CD1 LEU A 646 -15.929 41.935 16.865 1.00 31.59 C ATOM 841 CD2 LEU A 646 -13.684 41.222 17.792 1.00 31.74 C ATOM 842 N SER A 647 -13.266 45.462 15.236 1.00 33.10 N ATOM 843 CA SER A 647 -13.257 46.808 15.791 1.00 33.10 C ATOM 844 C SER A 647 -14.129 47.765 14.976 1.00 33.75 C ATOM 845 O SER A 647 -14.798 48.643 15.541 1.00 33.35 O ATOM 846 CB SER A 647 -11.834 47.366 15.929 1.00 33.02 C ATOM 847 OG SER A 647 -11.135 47.362 14.692 1.00 34.80 O ATOM 848 N GLU A 648 -14.101 47.601 13.656 1.00 33.41 N ATOM 849 CA GLU A 648 -14.932 48.397 12.747 1.00 34.85 C ATOM 850 C GLU A 648 -16.414 48.186 13.034 1.00 32.85 C ATOM 851 O GLU A 648 -17.151 49.154 13.189 1.00 32.60 O ATOM 852 CB GLU A 648 -14.621 48.040 11.287 1.00 34.26 C ATOM 853 CG GLU A 648 -13.392 48.741 10.742 1.00 38.34 C ATOM 854 CD GLU A 648 -12.795 48.072 9.492 1.00 39.86 C ATOM 855 OE1 GLU A 648 -13.321 47.035 9.004 1.00 47.20 O ATOM 856 OE2 GLU A 648 -11.773 48.588 9.001 1.00 46.10 O ATOM 857 N ALA A 649 -16.824 46.920 13.099 1.00 32.32 N ATOM 858 CA ALA A 649 -18.211 46.526 13.392 1.00 32.59 C ATOM 859 C ALA A 649 -18.665 47.084 14.731 1.00 32.28 C ATOM 860 O ALA A 649 -19.741 47.654 14.826 1.00 33.07 O ATOM 861 CB ALA A 649 -18.361 45.003 13.365 1.00 32.24 C ATOM 862 N VAL A 650 -17.826 46.965 15.761 1.00 31.91 N ATOM 863 CA VAL A 650 -18.202 47.466 17.084 1.00 31.38 C ATOM 864 C VAL A 650 -18.215 48.987 17.127 1.00 31.23 C ATOM 865 O VAL A 650 -19.132 49.592 17.693 1.00 30.13 O ATOM 866 CB VAL A 650 -17.323 46.882 18.209 1.00 31.79 C ATOM 867 CG1 VAL A 650 -17.674 47.532 19.573 1.00 30.57 C ATOM 868 CG2 VAL A 650 -17.472 45.362 18.234 1.00 30.81 C ATOM 869 N GLN A 651 -17.212 49.620 16.523 1.00 30.30 N ATOM 870 CA GLN A 651 -17.262 51.077 16.439 1.00 30.08 C ATOM 871 C GLN A 651 -18.518 51.566 15.685 1.00 29.39 C ATOM 872 O GLN A 651 -19.158 52.529 16.111 1.00 29.70 O ATOM 873 CB GLN A 651 -16.021 51.644 15.759 1.00 30.19 C ATOM 874 CG GLN A 651 -15.935 53.160 15.861 1.00 28.82 C ATOM 875 CD GLN A 651 -14.955 53.739 14.864 1.00 31.16 C ATOM 876 OE1 GLN A 651 -14.337 53.005 14.100 1.00 33.15 O ATOM 877 NE2 GLN A 651 -14.819 55.050 14.858 1.00 32.87 N ATOM 878 N ALA A 652 -18.843 50.919 14.565 1.00 29.24 N ATOM 879 CA ALA A 652 -20.030 51.298 13.776 1.00 28.09 C ATOM 880 C ALA A 652 -21.318 51.196 14.612 1.00 28.18 C ATOM 881 O ALA A 652 -22.132 52.100 14.593 1.00 27.86 O ATOM 882 CB ALA A 652 -20.139 50.448 12.520 1.00 27.66 C ATOM 883 N ALA A 653 -21.451 50.116 15.387 1.00 27.73 N ATOM 884 CA ALA A 653 -22.584 49.938 16.282 1.00 27.99 C ATOM 885 C ALA A 653 -22.732 51.089 17.274 1.00 28.08 C ATOM 886 O ALA A 653 -23.841 51.602 17.461 1.00 27.41 O ATOM 887 CB ALA A 653 -22.481 48.565 17.008 1.00 28.11 C ATOM 888 N CYS A 654 -21.620 51.510 17.903 1.00 27.68 N ATOM 889 CA CYS A 654 -21.627 52.664 18.817 1.00 28.26 C ATOM 890 C CYS A 654 -22.066 53.983 18.164 1.00 28.63 C ATOM 891 O CYS A 654 -22.780 54.771 18.779 1.00 28.06 O ATOM 892 CB CYS A 654 -20.240 52.879 19.469 1.00 28.71 C ATOM 893 SG CYS A 654 -19.659 51.477 20.517 1.00 29.78 S ATOM 894 N MET A 655 -21.580 54.238 16.947 1.00 29.18 N ATOM 895 CA MET A 655 -21.862 55.480 16.232 1.00 30.91 C ATOM 896 C MET A 655 -23.323 55.526 15.735 1.00 30.78 C ATOM 897 O MET A 655 -23.958 56.569 15.765 1.00 30.72 O ATOM 898 CB MET A 655 -20.887 55.641 15.044 1.00 30.48 C ATOM 899 CG MET A 655 -19.428 55.889 15.463 1.00 31.59 C ATOM 900 SD MET A 655 -18.277 56.236 14.097 1.00 34.16 S ATOM 901 CE MET A 655 -18.311 54.679 13.315 1.00 28.65 C ATOM 902 N LEU A 656 -23.831 54.386 15.279 1.00 32.18 N ATOM 903 CA LEU A 656 -25.254 54.236 14.920 1.00 33.98 C ATOM 904 C LEU A 656 -26.168 54.448 16.137 1.00 33.50 C ATOM 905 O LEU A 656 -27.165 55.177 16.082 1.00 32.69 O ATOM 906 CB LEU A 656 -25.496 52.832 14.393 1.00 34.15 C ATOM 907 CG LEU A 656 -25.589 52.432 12.939 1.00 39.72 C ATOM 908 CD1 LEU A 656 -26.066 50.980 12.932 1.00 42.40 C ATOM 909 CD2 LEU A 656 -26.576 53.299 12.153 1.00 42.32 C ATOM 910 N ARG A 657 -25.807 53.779 17.225 1.00 33.67 N ATOM 911 CA ARG A 657 -26.523 53.837 18.486 1.00 34.33 C ATOM 912 C ARG A 657 -26.649 55.243 19.055 1.00 34.69 C ATOM 913 O ARG A 657 -27.720 55.633 19.547 1.00 34.18 O ATOM 914 CB ARG A 657 -25.821 52.943 19.495 1.00 34.53 C ATOM 915 CG ARG A 657 -26.495 52.869 20.832 1.00 37.88 C ATOM 916 CD ARG A 657 -27.796 52.120 20.782 1.00 43.32 C ATOM 917 NE ARG A 657 -28.469 52.326 22.057 1.00 51.60 N ATOM 918 CZ ARG A 657 -29.726 51.984 22.322 1.00 54.68 C ATOM 919 NH1 ARG A 657 -30.488 51.392 21.390 1.00 54.53 N ATOM 920 NH2 ARG A 657 -30.216 52.245 23.529 1.00 54.75 N ATOM 921 N TYR A 658 -25.562 56.005 19.005 1.00 33.90 N ATOM 922 CA TYR A 658 -25.583 57.358 19.525 1.00 34.59 C ATOM 923 C TYR A 658 -26.546 58.271 18.749 1.00 35.31 C ATOM 924 O TYR A 658 -27.289 59.063 19.344 1.00 34.08 O ATOM 925 CB TYR A 658 -24.169 57.934 19.556 1.00 34.42 C ATOM 926 CG TYR A 658 -24.093 59.386 19.951 1.00 34.94 C ATOM 927 CD1 TYR A 658 -24.500 59.817 21.223 1.00 34.57 C ATOM 928 CD2 TYR A 658 -23.611 60.340 19.050 1.00 34.93 C ATOM 929 CE1 TYR A 658 -24.423 61.163 21.583 1.00 35.32 C ATOM 930 CE2 TYR A 658 -23.525 61.679 19.402 1.00 36.65 C ATOM 931 CZ TYR A 658 -23.935 62.084 20.664 1.00 35.71 C ATOM 932 OH TYR A 658 -23.832 63.415 20.987 1.00 37.00 O ATOM 933 N GLN A 659 -26.543 58.152 17.427 1.00 36.64 N ATOM 934 CA GLN A 659 -27.469 58.934 16.609 1.00 38.18 C ATOM 935 C GLN A 659 -28.936 58.521 16.876 1.00 39.29 C ATOM 936 O GLN A 659 -29.833 59.376 16.958 1.00 38.37 O ATOM 937 CB GLN A 659 -27.133 58.838 15.119 1.00 37.56 C ATOM 938 CG GLN A 659 -27.957 59.797 14.230 1.00 40.32 C ATOM 939 CD GLN A 659 -27.895 61.273 14.673 1.00 45.05 C ATOM 940 OE1 GLN A 659 -26.847 61.780 15.085 1.00 46.81 O ATOM 941 NE2 GLN A 659 -29.023 61.966 14.570 1.00 47.71 N ATOM 942 N LYS A 660 -29.168 57.220 17.011 1.00 40.98 N ATOM 943 CA LYS A 660 -30.510 56.723 17.352 1.00 43.19 C ATOM 944 C LYS A 660 -31.040 57.273 18.672 1.00 43.84 C ATOM 945 O LYS A 660 -32.203 57.671 18.750 1.00 44.21 O ATOM 946 CB LYS A 660 -30.583 55.206 17.294 1.00 42.96 C ATOM 947 CG LYS A 660 -30.997 54.731 15.909 1.00 46.37 C ATOM 948 CD LYS A 660 -30.893 53.224 15.763 1.00 50.01 C ATOM 949 CE LYS A 660 -30.466 52.815 14.343 1.00 51.48 C ATOM 950 NZ LYS A 660 -29.908 51.416 14.353 1.00 51.91 N ATOM 951 N CYS A 661 -30.175 57.339 19.677 1.00 45.01 N ATOM 952 CA CYS A 661 -30.516 57.920 20.974 1.00 46.89 C ATOM 953 C CYS A 661 -30.786 59.430 20.950 1.00 48.19 C ATOM 954 O CYS A 661 -31.763 59.889 21.553 1.00 48.16 O ATOM 955 CB CYS A 661 -29.472 57.533 22.030 1.00 46.61 C ATOM 956 SG CYS A 661 -29.435 55.702 22.312 1.00 48.96 S ATOM 957 N LEU A 662 -29.941 60.200 20.258 1.00 49.41 N ATOM 958 CA LEU A 662 -30.199 61.625 20.055 1.00 51.08 C ATOM 959 C LEU A 662 -31.549 61.844 19.380 1.00 52.54 C ATOM 960 O LEU A 662 -32.306 62.721 19.782 1.00 52.57 O ATOM 961 CB LEU A 662 -29.102 62.289 19.218 1.00 50.22 C ATOM 962 CG LEU A 662 -27.783 62.627 19.904 1.00 49.78 C ATOM 963 CD1 LEU A 662 -26.879 63.325 18.913 1.00 49.09 C ATOM 964 CD2 LEU A 662 -27.987 63.488 21.135 1.00 48.81 C ATOM 965 N ASP A 663 -31.821 61.040 18.352 1.00 54.79 N ATOM 966 CA ASP A 663 -33.063 61.094 17.584 1.00 57.33 C ATOM 967 C ASP A 663 -34.310 60.750 18.383 1.00 58.45 C ATOM 968 O ASP A 663 -35.327 61.430 18.256 1.00 58.71 O ATOM 969 CB ASP A 663 -32.984 60.179 16.366 1.00 57.71 C ATOM 970 CG ASP A 663 -32.964 60.947 15.064 1.00 60.51 C ATOM 971 OD1 ASP A 663 -32.375 62.058 15.039 1.00 61.61 O ATOM 972 OD2 ASP A 663 -33.551 60.434 14.071 1.00 63.95 O ATOM 973 N ALA A 664 -34.229 59.684 19.178 1.00 59.88 N ATOM 974 CA ALA A 664 -35.313 59.294 20.080 1.00 61.29 C ATOM 975 C ALA A 664 -35.678 60.442 21.027 1.00 62.49 C ATOM 976 O ALA A 664 -36.843 60.809 21.136 1.00 62.76 O ATOM 977 CB ALA A 664 -34.937 58.043 20.869 1.00 61.03 C ATOM 978 N ARG A 665 -34.673 61.030 21.668 1.00 63.62 N ATOM 979 CA ARG A 665 -34.889 62.055 22.686 1.00 65.35 C ATOM 980 C ARG A 665 -35.115 63.485 22.152 1.00 65.84 C ATOM 981 O ARG A 665 -35.423 64.392 22.925 1.00 66.29 O ATOM 982 CB ARG A 665 -33.759 61.996 23.728 1.00 65.20 C ATOM 983 CG ARG A 665 -33.562 60.563 24.272 1.00 66.62 C ATOM 984 CD ARG A 665 -32.638 60.440 25.483 1.00 66.98 C ATOM 985 NE ARG A 665 -32.783 59.115 26.099 1.00 71.00 N ATOM 986 CZ ARG A 665 -33.306 58.880 27.307 1.00 72.94 C ATOM 987 NH1 ARG A 665 -33.724 59.883 28.074 1.00 74.11 N ATOM 988 NH2 ARG A 665 -33.403 57.631 27.759 1.00 73.49 N ATOM 989 N SER A 666 -34.990 63.687 20.841 1.00 66.49 N ATOM 990 CA SER A 666 -35.189 65.014 20.255 1.00 66.99 C ATOM 991 C SER A 666 -36.668 65.308 19.978 1.00 67.28 C ATOM 992 O SER A 666 -37.398 64.459 19.462 1.00 67.48 O ATOM 993 CB SER A 666 -34.366 65.173 18.974 1.00 67.10 C ATOM 994 OG SER A 666 -34.904 64.392 17.921 1.00 67.35 O TER 995 SER A 666 ATOM 996 N ALA B 666 1.225 53.853 -0.387 1.00 65.58 N ATOM 997 CA ALA B 666 0.488 54.605 0.674 1.00 65.66 C ATOM 998 C ALA B 666 -0.340 53.659 1.554 1.00 65.56 C ATOM 999 O ALA B 666 -0.410 52.437 1.307 1.00 65.68 O ATOM 1000 CB ALA B 666 -0.406 55.697 0.053 1.00 65.60 C ATOM 1001 N VAL B 667 -0.972 54.238 2.572 1.00 64.89 N ATOM 1002 CA VAL B 667 -1.725 53.477 3.563 1.00 63.96 C ATOM 1003 C VAL B 667 -3.179 53.194 3.107 1.00 63.00 C ATOM 1004 O VAL B 667 -3.930 54.113 2.789 1.00 63.14 O ATOM 1005 CB VAL B 667 -1.604 54.151 4.974 1.00 64.24 C ATOM 1006 CG1 VAL B 667 -1.758 55.677 4.884 1.00 64.67 C ATOM 1007 CG2 VAL B 667 -2.569 53.556 5.985 1.00 64.32 C ATOM 1008 N THR B 668 -3.541 51.908 3.065 1.00 61.88 N ATOM 1009 CA THR B 668 -4.889 51.438 2.700 1.00 60.86 C ATOM 1010 C THR B 668 -5.945 51.834 3.747 1.00 59.92 C ATOM 1011 O THR B 668 -5.583 52.262 4.853 1.00 60.02 O ATOM 1012 CB THR B 668 -4.931 49.889 2.501 1.00 61.01 C ATOM 1013 OG1 THR B 668 -4.936 49.227 3.777 1.00 61.36 O ATOM 1014 CG2 THR B 668 -3.746 49.392 1.648 1.00 61.18 C ATOM 1015 N PRO B 669 -7.256 51.705 3.401 1.00 58.97 N ATOM 1016 CA PRO B 669 -8.344 52.027 4.350 1.00 57.72 C ATOM 1017 C PRO B 669 -8.281 51.216 5.654 1.00 56.21 C ATOM 1018 O PRO B 669 -8.362 51.798 6.741 1.00 55.60 O ATOM 1019 CB PRO B 669 -9.616 51.685 3.552 1.00 57.86 C ATOM 1020 CG PRO B 669 -9.204 51.812 2.108 1.00 58.36 C ATOM 1021 CD PRO B 669 -7.799 51.272 2.093 1.00 59.19 C ATOM 1022 N GLU B 670 -8.125 49.893 5.534 1.00 55.02 N ATOM 1023 CA GLU B 670 -7.951 49.007 6.693 1.00 53.93 C ATOM 1024 C GLU B 670 -6.837 49.526 7.613 1.00 53.40 C ATOM 1025 O GLU B 670 -7.028 49.613 8.824 1.00 52.89 O ATOM 1026 CB GLU B 670 -7.709 47.546 6.262 1.00 54.08 C ATOM 1027 CG GLU B 670 -7.288 46.609 7.409 1.00 53.68 C ATOM 1028 CD GLU B 670 -7.574 45.129 7.159 1.00 53.89 C ATOM 1029 OE1 GLU B 670 -8.733 44.777 6.871 1.00 54.58 O ATOM 1030 OE2 GLU B 670 -6.645 44.307 7.287 1.00 52.17 O ATOM 1031 N GLU B 671 -5.713 49.929 7.014 1.00 52.68 N ATOM 1032 CA GLU B 671 -4.513 50.407 7.738 1.00 52.20 C ATOM 1033 C GLU B 671 -4.664 51.722 8.509 1.00 51.04 C ATOM 1034 O GLU B 671 -4.245 51.816 9.662 1.00 50.35 O ATOM 1035 CB GLU B 671 -3.325 50.538 6.778 1.00 51.90 C ATOM 1036 CG GLU B 671 -2.801 49.221 6.247 1.00 53.53 C ATOM 1037 CD GLU B 671 -1.686 49.412 5.228 1.00 53.54 C ATOM 1038 OE1 GLU B 671 -1.687 50.433 4.505 1.00 53.49 O ATOM 1039 OE2 GLU B 671 -0.803 48.534 5.166 1.00 56.41 O ATOM 1040 N ARG B 672 -5.209 52.748 7.862 1.00 50.05 N ATOM 1041 CA ARG B 672 -5.407 54.035 8.523 1.00 50.17 C ATOM 1042 C ARG B 672 -6.383 53.924 9.722 1.00 48.46 C ATOM 1043 O ARG B 672 -6.176 54.569 10.758 1.00 48.13 O ATOM 1044 CB ARG B 672 -5.932 55.060 7.520 1.00 50.46 C ATOM 1045 CG ARG B 672 -5.790 56.524 7.932 1.00 52.34 C ATOM 1046 CD ARG B 672 -6.712 57.439 7.063 1.00 53.91 C ATOM 1047 NE ARG B 672 -7.026 56.863 5.742 1.00 60.70 N ATOM 1048 CZ ARG B 672 -8.134 56.171 5.468 1.00 63.00 C ATOM 1049 NH1 ARG B 672 -9.046 55.975 6.419 1.00 66.13 N ATOM 1050 NH2 ARG B 672 -8.334 55.670 4.254 1.00 63.23 N ATOM 1051 N AHIS B 673 -7.419 53.107 9.580 0.50 47.60 N ATOM 1052 N BHIS B 673 -7.443 53.131 9.538 0.50 47.42 N ATOM 1053 CA AHIS B 673 -8.372 52.916 10.664 0.50 46.83 C ATOM 1054 CA BHIS B 673 -8.412 52.807 10.591 0.50 46.50 C ATOM 1055 C AHIS B 673 -7.784 52.086 11.822 0.50 46.09 C ATOM 1056 C BHIS B 673 -7.719 52.143 11.785 0.50 45.90 C ATOM 1057 O AHIS B 673 -8.077 52.364 12.985 0.50 45.97 O ATOM 1058 O BHIS B 673 -7.880 52.584 12.925 0.50 45.75 O ATOM 1059 CB AHIS B 673 -9.673 52.309 10.144 0.50 46.74 C ATOM 1060 CB BHIS B 673 -9.532 51.893 10.050 0.50 46.23 C ATOM 1061 CG AHIS B 673 -10.869 52.652 10.977 0.50 47.01 C ATOM 1062 CG BHIS B 673 -10.141 50.994 11.090 0.50 45.56 C ATOM 1063 ND1AHIS B 673 -11.666 53.748 10.720 0.50 47.01 N ATOM 1064 ND1BHIS B 673 -11.134 51.413 11.950 0.50 44.95 N ATOM 1065 CD2AHIS B 673 -11.401 52.046 12.064 0.50 46.02 C ATOM 1066 CD2BHIS B 673 -9.883 49.705 11.415 0.50 45.21 C ATOM 1067 CE1AHIS B 673 -12.641 53.796 11.608 0.50 45.75 C ATOM 1068 CE1BHIS B 673 -11.460 50.421 12.759 0.50 44.55 C ATOM 1069 NE2AHIS B 673 -12.500 52.778 12.437 0.50 45.39 N ATOM 1070 NE2BHIS B 673 -10.707 49.377 12.463 0.50 44.10 N ATOM 1071 N LEU B 674 -6.957 51.085 11.506 1.00 45.34 N ATOM 1072 CA LEU B 674 -6.203 50.348 12.533 1.00 44.36 C ATOM 1073 C LEU B 674 -5.308 51.233 13.391 1.00 43.70 C ATOM 1074 O LEU B 674 -5.277 51.050 14.615 1.00 42.88 O ATOM 1075 CB LEU B 674 -5.363 49.217 11.926 1.00 44.47 C ATOM 1076 CG LEU B 674 -6.086 47.903 11.665 1.00 44.98 C ATOM 1077 CD1 LEU B 674 -5.247 46.985 10.756 1.00 46.09 C ATOM 1078 CD2 LEU B 674 -6.506 47.210 12.967 1.00 43.27 C ATOM 1079 N SER B 675 -4.599 52.190 12.766 1.00 42.73 N ATOM 1080 CA SER B 675 -3.688 53.088 13.510 1.00 42.48 C ATOM 1081 C SER B 675 -4.465 54.035 14.403 1.00 41.79 C ATOM 1082 O SER B 675 -4.031 54.341 15.518 1.00 41.72 O ATOM 1083 CB SER B 675 -2.776 53.908 12.575 1.00 42.69 C ATOM 1084 OG SER B 675 -2.086 53.063 11.680 1.00 44.63 O ATOM 1085 N LYS B 676 -5.589 54.528 13.892 1.00 40.60 N ATOM 1086 CA LYS B 676 -6.546 55.251 14.704 1.00 40.67 C ATOM 1087 C LYS B 676 -6.976 54.405 15.919 1.00 38.99 C ATOM 1088 O LYS B 676 -6.864 54.871 17.031 1.00 38.80 O ATOM 1089 CB LYS B 676 -7.776 55.651 13.895 1.00 40.82 C ATOM 1090 CG LYS B 676 -7.564 56.813 12.950 1.00 43.92 C ATOM 1091 CD LYS B 676 -8.591 56.754 11.818 1.00 48.32 C ATOM 1092 CE LYS B 676 -8.521 58.003 10.937 1.00 49.53 C ATOM 1093 NZ LYS B 676 -9.718 58.035 10.066 1.00 51.41 N ATOM 1094 N MET B 677 -7.457 53.186 15.684 1.00 38.65 N ATOM 1095 CA MET B 677 -7.936 52.289 16.751 1.00 38.76 C ATOM 1096 C MET B 677 -6.828 51.959 17.774 1.00 38.50 C ATOM 1097 O MET B 677 -7.104 51.852 18.975 1.00 38.07 O ATOM 1098 CB MET B 677 -8.474 50.974 16.180 1.00 39.11 C ATOM 1099 CG MET B 677 -9.877 51.008 15.578 1.00 41.20 C ATOM 1100 SD MET B 677 -11.199 51.559 16.698 1.00 46.43 S ATOM 1101 CE MET B 677 -11.046 53.329 16.520 1.00 38.54 C ATOM 1102 N GLN B 678 -5.592 51.806 17.286 1.00 37.59 N ATOM 1103 CA GLN B 678 -4.426 51.528 18.146 1.00 37.74 C ATOM 1104 C GLN B 678 -3.971 52.742 18.919 1.00 38.08 C ATOM 1105 O GLN B 678 -3.667 52.654 20.111 1.00 37.64 O ATOM 1106 CB GLN B 678 -3.272 50.955 17.343 1.00 36.77 C ATOM 1107 CG GLN B 678 -3.467 49.539 16.967 1.00 37.42 C ATOM 1108 CD GLN B 678 -2.370 49.023 16.043 1.00 39.76 C ATOM 1109 OE1 GLN B 678 -2.084 49.632 15.013 1.00 40.00 O ATOM 1110 NE2 GLN B 678 -1.777 47.886 16.395 1.00 36.02 N ATOM 1111 N GLN B 679 -3.951 53.892 18.261 1.00 39.31 N ATOM 1112 CA GLN B 679 -3.338 55.057 18.862 1.00 40.97 C ATOM 1113 C GLN B 679 -4.267 55.769 19.827 1.00 39.93 C ATOM 1114 O GLN B 679 -3.828 56.230 20.884 1.00 39.76 O ATOM 1115 CB GLN B 679 -2.799 56.019 17.784 1.00 41.08 C ATOM 1116 CG GLN B 679 -1.551 55.459 17.056 1.00 44.36 C ATOM 1117 CD GLN B 679 -0.947 56.441 16.060 1.00 45.39 C ATOM 1118 OE1 GLN B 679 -0.885 57.653 16.319 1.00 50.74 O ATOM 1119 NE2 GLN B 679 -0.506 55.923 14.906 1.00 50.17 N ATOM 1120 N ASN B 680 -5.542 55.868 19.456 1.00 39.25 N ATOM 1121 CA ASN B 680 -6.544 56.550 20.297 1.00 39.15 C ATOM 1122 C ASN B 680 -7.670 55.663 20.803 1.00 37.92 C ATOM 1123 O ASN B 680 -8.338 56.023 21.755 1.00 37.95 O ATOM 1124 CB ASN B 680 -7.197 57.726 19.555 1.00 39.27 C ATOM 1125 CG ASN B 680 -6.217 58.856 19.226 1.00 42.85 C ATOM 1126 OD1 ASN B 680 -6.120 59.269 18.061 1.00 44.52 O ATOM 1127 ND2 ASN B 680 -5.514 59.384 20.248 1.00 43.70 N ATOM 1128 N GLY B 681 -7.894 54.533 20.151 1.00 37.43 N ATOM 1129 CA GLY B 681 -9.135 53.797 20.289 1.00 36.89 C ATOM 1130 C GLY B 681 -10.340 54.683 20.012 1.00 37.23 C ATOM 1131 O GLY B 681 -10.218 55.770 19.410 1.00 36.49 O ATOM 1132 N TYR B 682 -11.503 54.239 20.485 1.00 36.25 N ATOM 1133 CA TYR B 682 -12.730 54.991 20.310 1.00 35.50 C ATOM 1134 C TYR B 682 -13.543 55.086 21.611 1.00 35.21 C ATOM 1135 O TYR B 682 -13.916 54.061 22.184 1.00 33.25 O ATOM 1136 CB TYR B 682 -13.554 54.329 19.212 1.00 36.20 C ATOM 1137 CG TYR B 682 -14.853 55.040 18.885 1.00 37.59 C ATOM 1138 CD1 TYR B 682 -14.844 56.251 18.182 1.00 35.51 C ATOM 1139 CD2 TYR B 682 -16.094 54.498 19.272 1.00 37.34 C ATOM 1140 CE1 TYR B 682 -16.029 56.908 17.881 1.00 37.96 C ATOM 1141 CE2 TYR B 682 -17.297 55.152 18.961 1.00 36.48 C ATOM 1142 CZ TYR B 682 -17.248 56.359 18.264 1.00 38.04 C ATOM 1143 OH TYR B 682 -18.407 57.048 17.941 1.00 39.89 O ATOM 1144 N GLU B 683 -13.808 56.319 22.050 1.00 34.48 N ATOM 1145 CA GLU B 683 -14.704 56.586 23.164 1.00 35.06 C ATOM 1146 C GLU B 683 -16.159 56.653 22.681 1.00 33.89 C ATOM 1147 O GLU B 683 -16.527 57.518 21.879 1.00 33.18 O ATOM 1148 CB GLU B 683 -14.350 57.890 23.869 1.00 34.54 C ATOM 1149 CG GLU B 683 -13.044 57.846 24.633 1.00 36.47 C ATOM 1150 CD GLU B 683 -12.694 59.170 25.309 1.00 37.55 C ATOM 1151 OE1 GLU B 683 -13.594 59.990 25.533 1.00 40.87 O ATOM 1152 OE2 GLU B 683 -11.506 59.382 25.633 1.00 42.22 O ATOM 1153 N ASN B 684 -16.981 55.743 23.195 1.00 32.67 N ATOM 1154 CA ASN B 684 -18.372 55.638 22.773 1.00 32.47 C ATOM 1155 C ASN B 684 -19.162 56.869 23.212 1.00 32.22 C ATOM 1156 O ASN B 684 -19.304 57.123 24.398 1.00 31.99 O ATOM 1157 CB ASN B 684 -18.979 54.350 23.335 1.00 32.18 C ATOM 1158 CG ASN B 684 -20.423 54.128 22.910 1.00 32.70 C ATOM 1159 OD1 ASN B 684 -20.984 54.842 22.059 1.00 31.61 O ATOM 1160 ND2 ASN B 684 -21.026 53.125 23.492 1.00 29.58 N ATOM 1161 N PRO B 685 -19.682 57.657 22.245 1.00 33.14 N ATOM 1162 CA PRO B 685 -20.442 58.820 22.712 1.00 33.75 C ATOM 1163 C PRO B 685 -21.816 58.432 23.286 1.00 35.06 C ATOM 1164 O PRO B 685 -22.395 59.222 24.021 1.00 35.32 O ATOM 1165 CB PRO B 685 -20.578 59.691 21.456 1.00 33.53 C ATOM 1166 CG PRO B 685 -20.448 58.728 20.320 1.00 33.68 C ATOM 1167 CD PRO B 685 -19.638 57.553 20.773 1.00 31.95 C ATOM 1168 N THR B 686 -22.326 57.240 22.972 1.00 36.55 N ATOM 1169 CA THR B 686 -23.607 56.792 23.568 1.00 38.52 C ATOM 1170 C THR B 686 -23.456 56.696 25.084 1.00 39.59 C ATOM 1171 O THR B 686 -24.328 57.136 25.826 1.00 40.45 O ATOM 1172 CB THR B 686 -24.110 55.431 23.039 1.00 38.41 C ATOM 1173 OG1 THR B 686 -23.908 55.333 21.627 1.00 37.73 O ATOM 1174 CG2 THR B 686 -25.610 55.251 23.367 1.00 39.57 C ATOM 1175 N TYR B 687 -22.334 56.146 25.539 1.00 41.10 N ATOM 1176 CA TYR B 687 -21.999 56.100 26.969 1.00 42.62 C ATOM 1177 C TYR B 687 -21.997 57.450 27.661 1.00 44.98 C ATOM 1178 O TYR B 687 -22.670 57.631 28.677 1.00 44.81 O ATOM 1179 CB TYR B 687 -20.670 55.372 27.208 1.00 41.94 C ATOM 1180 CG TYR B 687 -20.252 55.338 28.658 1.00 40.93 C ATOM 1181 CD1 TYR B 687 -20.912 54.511 29.587 1.00 40.28 C ATOM 1182 CD2 TYR B 687 -19.213 56.139 29.111 1.00 38.42 C ATOM 1183 CE1 TYR B 687 -20.530 54.497 30.936 1.00 39.81 C ATOM 1184 CE2 TYR B 687 -18.818 56.118 30.442 1.00 41.31 C ATOM 1185 CZ TYR B 687 -19.483 55.300 31.349 1.00 40.67 C ATOM 1186 OH TYR B 687 -19.080 55.309 32.664 1.00 42.63 O ATOM 1187 N LYS B 688 -21.225 58.389 27.122 1.00 47.87 N ATOM 1188 CA LYS B 688 -21.176 59.754 27.635 1.00 51.05 C ATOM 1189 C LYS B 688 -22.535 60.481 27.606 1.00 52.82 C ATOM 1190 O LYS B 688 -22.903 61.141 28.570 1.00 53.08 O ATOM 1191 CB LYS B 688 -20.130 60.562 26.876 1.00 51.25 C ATOM 1192 CG LYS B 688 -18.705 60.241 27.286 1.00 52.98 C ATOM 1193 CD LYS B 688 -17.713 61.142 26.571 1.00 56.42 C ATOM 1194 CE LYS B 688 -17.500 60.693 25.140 1.00 57.41 C ATOM 1195 NZ LYS B 688 -16.205 61.205 24.632 1.00 58.51 N ATOM 1196 N PHE B 689 -23.262 60.354 26.501 1.00 55.13 N ATOM 1197 CA PHE B 689 -24.617 60.887 26.372 1.00 57.54 C ATOM 1198 C PHE B 689 -25.511 60.521 27.580 1.00 58.93 C ATOM 1199 O PHE B 689 -26.025 61.409 28.270 1.00 59.07 O ATOM 1200 CB PHE B 689 -25.220 60.386 25.057 1.00 57.82 C ATOM 1201 CG PHE B 689 -26.669 60.727 24.866 1.00 59.24 C ATOM 1202 CD1 PHE B 689 -27.083 62.055 24.768 1.00 60.86 C ATOM 1203 CD2 PHE B 689 -27.616 59.713 24.737 1.00 60.39 C ATOM 1204 CE1 PHE B 689 -28.431 62.374 24.573 1.00 62.18 C ATOM 1205 CE2 PHE B 689 -28.959 60.013 24.540 1.00 61.96 C ATOM 1206 CZ PHE B 689 -29.371 61.351 24.455 1.00 61.27 C ATOM 1207 N PHE B 690 -25.667 59.223 27.842 1.00 60.60 N ATOM 1208 CA PHE B 690 -26.433 58.756 28.996 1.00 62.62 C ATOM 1209 C PHE B 690 -25.756 59.097 30.324 1.00 64.34 C ATOM 1210 O PHE B 690 -26.430 59.309 31.326 1.00 64.77 O ATOM 1211 CB PHE B 690 -26.725 57.255 28.900 1.00 62.08 C ATOM 1212 CG PHE B 690 -27.787 56.906 27.886 1.00 62.43 C ATOM 1213 CD1 PHE B 690 -29.097 57.388 28.027 1.00 61.07 C ATOM 1214 CD2 PHE B 690 -27.486 56.098 26.788 1.00 61.38 C ATOM 1215 CE1 PHE B 690 -30.077 57.073 27.095 1.00 60.52 C ATOM 1216 CE2 PHE B 690 -28.468 55.780 25.847 1.00 61.57 C ATOM 1217 CZ PHE B 690 -29.767 56.271 26.001 1.00 61.28 C ATOM 1218 N GLU B 691 -24.428 59.180 30.315 1.00 66.58 N ATOM 1219 CA GLU B 691 -23.649 59.495 31.514 1.00 68.67 C ATOM 1220 C GLU B 691 -23.897 60.918 32.004 1.00 70.28 C ATOM 1221 O GLU B 691 -24.091 61.135 33.203 1.00 70.70 O ATOM 1222 CB GLU B 691 -22.150 59.271 31.260 1.00 68.63 C ATOM 1223 CG GLU B 691 -21.258 59.362 32.491 1.00 68.58 C ATOM 1224 CD GLU B 691 -21.423 58.188 33.440 1.00 68.44 C ATOM 1225 OE1 GLU B 691 -21.998 57.158 33.030 1.00 67.71 O ATOM 1226 OE2 GLU B 691 -20.968 58.296 34.602 1.00 69.40 O ATOM 1227 N GLN B 692 -23.889 61.875 31.075 1.00 72.14 N ATOM 1228 CA GLN B 692 -24.149 63.286 31.384 1.00 73.95 C ATOM 1229 C GLN B 692 -25.551 63.537 31.967 1.00 74.82 C ATOM 1230 O GLN B 692 -25.779 64.551 32.638 1.00 74.93 O ATOM 1231 CB GLN B 692 -23.899 64.160 30.150 1.00 74.03 C ATOM 1232 CG GLN B 692 -22.432 64.537 29.972 1.00 75.57 C ATOM 1233 CD GLN B 692 -22.020 64.662 28.511 1.00 77.35 C ATOM 1234 OE1 GLN B 692 -22.829 65.015 27.645 1.00 77.72 O ATOM 1235 NE2 GLN B 692 -20.748 64.373 28.231 1.00 77.36 N ATOM 1236 N MET B 693 -26.474 62.609 31.708 1.00 75.75 N ATOM 1237 CA MET B 693 -27.773 62.578 32.380 1.00 76.94 C ATOM 1238 C MET B 693 -27.644 61.909 33.753 1.00 76.88 C ATOM 1239 O MET B 693 -27.585 62.577 34.788 1.00 77.12 O ATOM 1240 CB MET B 693 -28.791 61.807 31.538 1.00 76.76 C ATOM 1241 CG MET B 693 -29.344 62.566 30.345 1.00 77.33 C ATOM 1242 SD MET B 693 -30.058 61.464 29.091 1.00 78.84 S ATOM 1243 CE MET B 693 -31.129 60.396 30.074 1.00 78.90 C TER 1244 MET B 693 ATOM 1245 N PHE C 543 12.191 37.440 44.235 1.00 46.75 N ATOM 1246 CA PHE C 543 12.868 38.165 43.134 1.00 46.29 C ATOM 1247 C PHE C 543 13.396 37.226 42.034 1.00 45.18 C ATOM 1248 O PHE C 543 14.346 36.456 42.257 1.00 44.87 O ATOM 1249 CB PHE C 543 13.996 39.043 43.672 1.00 47.26 C ATOM 1250 CG PHE C 543 14.744 39.763 42.593 1.00 49.61 C ATOM 1251 CD1 PHE C 543 14.179 40.872 41.958 1.00 51.43 C ATOM 1252 CD2 PHE C 543 15.993 39.312 42.170 1.00 50.75 C ATOM 1253 CE1 PHE C 543 14.856 41.531 40.942 1.00 51.42 C ATOM 1254 CE2 PHE C 543 16.666 39.961 41.164 1.00 51.74 C ATOM 1255 CZ PHE C 543 16.086 41.079 40.543 1.00 51.03 C ATOM 1256 N GLN C 544 12.763 37.294 40.858 1.00 43.07 N ATOM 1257 CA GLN C 544 13.173 36.510 39.683 1.00 41.47 C ATOM 1258 C GLN C 544 12.857 37.216 38.345 1.00 39.58 C ATOM 1259 O GLN C 544 11.780 37.750 38.155 1.00 39.02 O ATOM 1260 CB GLN C 544 12.529 35.122 39.712 1.00 41.29 C ATOM 1261 CG GLN C 544 12.988 34.171 38.599 1.00 42.22 C ATOM 1262 CD GLN C 544 14.458 33.816 38.660 1.00 43.33 C ATOM 1263 OE1 GLN C 544 14.941 33.313 39.674 1.00 45.69 O ATOM 1264 NE2 GLN C 544 15.181 34.060 37.565 1.00 42.23 N ATOM 1265 N VAL C 545 13.816 37.184 37.434 1.00 38.55 N ATOM 1266 CA VAL C 545 13.656 37.703 36.072 1.00 37.25 C ATOM 1267 C VAL C 545 13.562 36.530 35.107 1.00 36.22 C ATOM 1268 O VAL C 545 14.238 35.527 35.291 1.00 36.46 O ATOM 1269 CB VAL C 545 14.853 38.605 35.725 1.00 37.01 C ATOM 1270 CG1 VAL C 545 14.871 39.022 34.249 1.00 36.34 C ATOM 1271 CG2 VAL C 545 14.863 39.801 36.658 1.00 36.82 C ATOM 1272 N TYR C 546 12.709 36.656 34.102 1.00 35.26 N ATOM 1273 CA TYR C 546 12.621 35.691 33.008 1.00 34.58 C ATOM 1274 C TYR C 546 12.862 36.422 31.713 1.00 33.76 C ATOM 1275 O TYR C 546 12.243 37.461 31.462 1.00 32.67 O ATOM 1276 CB TYR C 546 11.256 35.010 32.964 1.00 35.60 C ATOM 1277 CG TYR C 546 10.934 34.253 34.226 1.00 37.23 C ATOM 1278 CD1 TYR C 546 10.335 34.895 35.312 1.00 37.47 C ATOM 1279 CD2 TYR C 546 11.251 32.900 34.343 1.00 37.72 C ATOM 1280 CE1 TYR C 546 10.054 34.201 36.499 1.00 40.27 C ATOM 1281 CE2 TYR C 546 10.983 32.192 35.519 1.00 39.49 C ATOM 1282 CZ TYR C 546 10.385 32.843 36.587 1.00 39.62 C ATOM 1283 OH TYR C 546 10.106 32.140 37.729 1.00 39.72 O ATOM 1284 N TYR C 547 13.798 35.903 30.923 1.00 32.77 N ATOM 1285 CA TYR C 547 14.016 36.389 29.575 1.00 33.06 C ATOM 1286 C TYR C 547 12.910 35.867 28.671 1.00 33.20 C ATOM 1287 O TYR C 547 12.734 34.649 28.538 1.00 33.96 O ATOM 1288 CB TYR C 547 15.349 35.895 29.035 1.00 32.24 C ATOM 1289 CG TYR C 547 15.767 36.549 27.736 1.00 32.00 C ATOM 1290 CD1 TYR C 547 15.522 37.912 27.504 1.00 29.75 C ATOM 1291 CD2 TYR C 547 16.453 35.818 26.755 1.00 31.53 C ATOM 1292 CE1 TYR C 547 15.914 38.522 26.323 1.00 29.59 C ATOM 1293 CE2 TYR C 547 16.867 36.419 25.581 1.00 30.96 C ATOM 1294 CZ TYR C 547 16.587 37.766 25.364 1.00 32.17 C ATOM 1295 OH TYR C 547 17.014 38.353 24.199 1.00 32.42 O ATOM 1296 N LEU C 548 12.182 36.776 28.038 1.00 32.61 N ATOM 1297 CA LEU C 548 11.068 36.367 27.162 1.00 32.70 C ATOM 1298 C LEU C 548 11.532 36.206 25.724 1.00 32.59 C ATOM 1299 O LEU C 548 10.822 35.633 24.910 1.00 33.20 O ATOM 1300 CB LEU C 548 9.877 37.349 27.253 1.00 31.71 C ATOM 1301 CG LEU C 548 9.296 37.654 28.639 1.00 31.01 C ATOM 1302 CD1 LEU C 548 8.196 38.709 28.594 1.00 29.18 C ATOM 1303 CD2 LEU C 548 8.764 36.384 29.300 1.00 31.19 C ATOM 1304 N GLY C 549 12.736 36.705 25.424 1.00 32.91 N ATOM 1305 CA GLY C 549 13.279 36.678 24.084 1.00 32.68 C ATOM 1306 C GLY C 549 13.323 38.064 23.455 1.00 33.58 C ATOM 1307 O GLY C 549 13.218 39.097 24.142 1.00 32.78 O ATOM 1308 N ASN C 550 13.497 38.083 22.139 1.00 33.61 N ATOM 1309 CA ASN C 550 13.633 39.328 21.410 1.00 35.26 C ATOM 1310 C ASN C 550 12.884 39.256 20.086 1.00 35.48 C ATOM 1311 O ASN C 550 12.673 38.166 19.559 1.00 36.79 O ATOM 1312 CB ASN C 550 15.113 39.708 21.227 1.00 34.84 C ATOM 1313 CG ASN C 550 15.899 38.664 20.457 1.00 37.33 C ATOM 1314 OD1 ASN C 550 15.748 38.525 19.234 1.00 41.16 O ATOM 1315 ND2 ASN C 550 16.754 37.924 21.167 1.00 35.68 N ATOM 1316 N VAL C 551 12.438 40.407 19.585 1.00 35.10 N ATOM 1317 CA VAL C 551 11.737 40.491 18.310 1.00 34.58 C ATOM 1318 C VAL C 551 12.197 41.753 17.574 1.00 34.53 C ATOM 1319 O VAL C 551 12.614 42.722 18.214 1.00 33.71 O ATOM 1320 CB VAL C 551 10.177 40.546 18.469 1.00 34.76 C ATOM 1321 CG1 VAL C 551 9.618 39.253 19.090 1.00 36.20 C ATOM 1322 CG2 VAL C 551 9.719 41.785 19.242 1.00 32.49 C ATOM 1323 N PRO C 552 12.112 41.752 16.227 1.00 34.70 N ATOM 1324 CA PRO C 552 12.378 42.988 15.498 1.00 34.24 C ATOM 1325 C PRO C 552 11.284 43.999 15.770 1.00 34.04 C ATOM 1326 O PRO C 552 10.122 43.621 15.970 1.00 34.71 O ATOM 1327 CB PRO C 552 12.307 42.553 14.022 1.00 35.38 C ATOM 1328 CG PRO C 552 12.470 41.060 14.027 1.00 34.96 C ATOM 1329 CD PRO C 552 11.782 40.637 15.311 1.00 35.00 C ATOM 1330 N VAL C 553 11.649 45.270 15.812 1.00 32.53 N ATOM 1331 CA VAL C 553 10.667 46.323 15.896 1.00 31.69 C ATOM 1332 C VAL C 553 11.049 47.353 14.848 1.00 32.51 C ATOM 1333 O VAL C 553 12.180 47.362 14.397 1.00 31.67 O ATOM 1334 CB VAL C 553 10.568 46.946 17.317 1.00 31.80 C ATOM 1335 CG1 VAL C 553 9.872 45.952 18.288 1.00 29.45 C ATOM 1336 CG2 VAL C 553 11.946 47.403 17.836 1.00 29.49 C ATOM 1337 N ALA C 554 10.106 48.217 14.498 1.00 32.90 N ATOM 1338 CA ALA C 554 10.242 49.125 13.374 1.00 33.78 C ATOM 1339 C ALA C 554 10.922 50.446 13.702 1.00 34.06 C ATOM 1340 O ALA C 554 11.441 51.099 12.808 1.00 34.91 O ATOM 1341 CB ALA C 554 8.857 49.371 12.732 1.00 34.34 C ATOM 1342 N LYS C 555 10.926 50.824 14.980 1.00 33.89 N ATOM 1343 CA LYS C 555 11.385 52.131 15.426 1.00 33.64 C ATOM 1344 C LYS C 555 12.331 51.948 16.623 1.00 32.75 C ATOM 1345 O LYS C 555 12.241 50.940 17.320 1.00 32.51 O ATOM 1346 CB LYS C 555 10.184 52.973 15.863 1.00 33.89 C ATOM 1347 CG LYS C 555 9.352 53.517 14.719 1.00 38.21 C ATOM 1348 CD LYS C 555 8.033 54.080 15.233 1.00 43.18 C ATOM 1349 CE LYS C 555 7.096 54.435 14.079 1.00 48.06 C ATOM 1350 NZ LYS C 555 5.706 54.723 14.574 1.00 48.69 N ATOM 1351 N PRO C 556 13.231 52.915 16.865 1.00 32.27 N ATOM 1352 CA PRO C 556 14.128 52.791 18.016 1.00 31.84 C ATOM 1353 C PRO C 556 13.509 53.233 19.361 1.00 31.63 C ATOM 1354 O PRO C 556 14.090 52.944 20.399 1.00 30.69 O ATOM 1355 CB PRO C 556 15.281 53.729 17.662 1.00 30.76 C ATOM 1356 CG PRO C 556 14.650 54.782 16.800 1.00 32.98 C ATOM 1357 CD PRO C 556 13.502 54.139 16.077 1.00 32.57 C ATOM 1358 N VAL C 557 12.401 53.973 19.339 1.00 31.42 N ATOM 1359 CA VAL C 557 11.783 54.450 20.589 1.00 32.25 C ATOM 1360 C VAL C 557 10.265 54.280 20.581 1.00 32.08 C ATOM 1361 O VAL C 557 9.656 54.171 19.515 1.00 32.08 O ATOM 1362 CB VAL C 557 12.130 55.926 20.930 1.00 31.49 C ATOM 1363 CG1 VAL C 557 13.666 56.147 21.023 1.00 32.18 C ATOM 1364 CG2 VAL C 557 11.496 56.877 19.932 1.00 34.90 C ATOM 1365 N GLY C 558 9.669 54.280 21.772 1.00 31.27 N ATOM 1366 CA GLY C 558 8.216 54.295 21.895 1.00 30.84 C ATOM 1367 C GLY C 558 7.652 53.250 22.846 1.00 29.77 C ATOM 1368 O GLY C 558 7.883 52.061 22.689 1.00 28.58 O ATOM 1369 N VAL C 559 6.893 53.703 23.833 1.00 30.34 N ATOM 1370 CA VAL C 559 6.181 52.757 24.692 1.00 30.65 C ATOM 1371 C VAL C 559 5.170 51.945 23.879 1.00 30.57 C ATOM 1372 O VAL C 559 4.919 50.789 24.170 1.00 30.05 O ATOM 1373 CB VAL C 559 5.560 53.442 25.946 1.00 31.63 C ATOM 1374 CG1 VAL C 559 6.633 54.138 26.746 1.00 31.47 C ATOM 1375 CG2 VAL C 559 4.480 54.420 25.570 1.00 33.10 C ATOM 1376 N ASP C 560 4.626 52.539 22.819 1.00 30.56 N ATOM 1377 CA ASP C 560 3.743 51.805 21.906 1.00 30.56 C ATOM 1378 C ASP C 560 4.481 50.644 21.249 1.00 29.60 C ATOM 1379 O ASP C 560 3.935 49.549 21.058 1.00 29.39 O ATOM 1380 CB ASP C 560 3.187 52.758 20.823 1.00 31.38 C ATOM 1381 CG ASP C 560 4.290 53.404 19.964 1.00 35.41 C ATOM 1382 OD1 ASP C 560 5.252 53.996 20.522 1.00 38.02 O ATOM 1383 OD2 ASP C 560 4.193 53.314 18.715 1.00 41.95 O ATOM 1384 N VAL C 561 5.739 50.899 20.889 1.00 28.57 N ATOM 1385 CA VAL C 561 6.579 49.896 20.258 1.00 27.36 C ATOM 1386 C VAL C 561 6.870 48.722 21.219 1.00 26.38 C ATOM 1387 O VAL C 561 6.663 47.563 20.882 1.00 26.58 O ATOM 1388 CB VAL C 561 7.909 50.549 19.687 1.00 27.69 C ATOM 1389 CG1 VAL C 561 8.822 49.484 19.093 1.00 27.97 C ATOM 1390 CG2 VAL C 561 7.602 51.590 18.639 1.00 27.26 C ATOM 1391 N ILE C 562 7.339 49.019 22.421 1.00 25.91 N ATOM 1392 CA ILE C 562 7.659 47.937 23.359 1.00 25.84 C ATOM 1393 C ILE C 562 6.404 47.163 23.814 1.00 24.68 C ATOM 1394 O ILE C 562 6.466 45.971 24.027 1.00 24.47 O ATOM 1395 CB ILE C 562 8.521 48.421 24.572 1.00 26.04 C ATOM 1396 CG1 ILE C 562 7.767 49.426 25.451 1.00 27.98 C ATOM 1397 CG2 ILE C 562 9.844 49.007 24.078 1.00 23.96 C ATOM 1398 CD1 ILE C 562 7.105 48.802 26.701 1.00 29.91 C ATOM 1399 N ASN C 563 5.274 47.851 23.935 1.00 24.47 N ATOM 1400 CA ASN C 563 4.040 47.190 24.382 1.00 24.36 C ATOM 1401 C ASN C 563 3.498 46.308 23.281 1.00 24.26 C ATOM 1402 O ASN C 563 3.013 45.211 23.545 1.00 24.53 O ATOM 1403 CB ASN C 563 3.020 48.228 24.887 1.00 24.95 C ATOM 1404 CG ASN C 563 3.279 48.626 26.330 1.00 24.26 C ATOM 1405 OD1 ASN C 563 3.312 47.770 27.208 1.00 25.31 O ATOM 1406 ND2 ASN C 563 3.505 49.893 26.577 1.00 23.44 N ATOM 1407 N GLY C 564 3.670 46.748 22.028 1.00 24.08 N ATOM 1408 CA GLY C 564 3.382 45.906 20.881 1.00 24.45 C ATOM 1409 C GLY C 564 4.192 44.644 20.887 1.00 25.10 C ATOM 1410 O GLY C 564 3.662 43.548 20.684 1.00 26.04 O ATOM 1411 N ALA C 565 5.493 44.802 21.129 1.00 25.90 N ATOM 1412 CA ALA C 565 6.421 43.679 21.185 1.00 25.94 C ATOM 1413 C ALA C 565 6.084 42.730 22.336 1.00 26.07 C ATOM 1414 O ALA C 565 6.107 41.516 22.168 1.00 25.47 O ATOM 1415 CB ALA C 565 7.868 44.191 21.312 1.00 25.88 C ATOM 1416 N LEU C 566 5.777 43.296 23.502 1.00 26.21 N ATOM 1417 CA LEU C 566 5.397 42.485 24.670 1.00 26.85 C ATOM 1418 C LEU C 566 4.140 41.686 24.428 1.00 27.49 C ATOM 1419 O LEU C 566 4.105 40.486 24.684 1.00 28.35 O ATOM 1420 CB LEU C 566 5.216 43.367 25.903 1.00 26.39 C ATOM 1421 CG LEU C 566 6.514 43.861 26.528 1.00 26.02 C ATOM 1422 CD1 LEU C 566 6.227 45.037 27.463 1.00 23.81 C ATOM 1423 CD2 LEU C 566 7.252 42.729 27.252 1.00 25.60 C ATOM 1424 N GLU C 567 3.099 42.328 23.900 1.00 28.37 N ATOM 1425 CA GLU C 567 1.873 41.585 23.589 1.00 28.66 C ATOM 1426 C GLU C 567 2.145 40.428 22.630 1.00 29.32 C ATOM 1427 O GLU C 567 1.613 39.334 22.790 1.00 28.94 O ATOM 1428 CB GLU C 567 0.804 42.537 23.054 1.00 27.75 C ATOM 1429 CG GLU C 567 0.259 43.393 24.171 1.00 27.35 C ATOM 1430 CD GLU C 567 -0.627 44.535 23.725 1.00 29.73 C ATOM 1431 OE1 GLU C 567 -0.971 44.622 22.519 1.00 31.55 O ATOM 1432 OE2 GLU C 567 -0.984 45.349 24.605 1.00 29.00 O ATOM 1433 N SER C 568 2.981 40.673 21.623 1.00 30.53 N ATOM 1434 CA SER C 568 3.285 39.644 20.639 1.00 31.49 C ATOM 1435 C SER C 568 3.987 38.432 21.268 1.00 32.09 C ATOM 1436 O SER C 568 3.559 37.277 21.074 1.00 32.64 O ATOM 1437 CB SER C 568 4.114 40.251 19.511 1.00 32.42 C ATOM 1438 OG SER C 568 4.463 39.268 18.589 1.00 36.45 O ATOM 1439 N VAL C 569 5.020 38.686 22.070 1.00 32.07 N ATOM 1440 CA VAL C 569 5.750 37.581 22.697 1.00 32.36 C ATOM 1441 C VAL C 569 4.936 36.892 23.794 1.00 32.51 C ATOM 1442 O VAL C 569 4.982 35.665 23.911 1.00 32.78 O ATOM 1443 CB VAL C 569 7.174 38.001 23.211 1.00 32.37 C ATOM 1444 CG1 VAL C 569 7.107 38.712 24.566 1.00 30.50 C ATOM 1445 CG2 VAL C 569 8.082 36.783 23.270 1.00 33.63 C ATOM 1446 N LEU C 570 4.189 37.664 24.590 1.00 31.78 N ATOM 1447 CA LEU C 570 3.281 37.054 25.591 1.00 31.75 C ATOM 1448 C LEU C 570 2.233 36.138 24.943 1.00 33.20 C ATOM 1449 O LEU C 570 1.914 35.089 25.498 1.00 32.57 O ATOM 1450 CB LEU C 570 2.622 38.111 26.493 1.00 30.73 C ATOM 1451 CG LEU C 570 3.569 38.897 27.413 1.00 28.99 C ATOM 1452 CD1 LEU C 570 2.902 40.093 28.062 1.00 25.40 C ATOM 1453 CD2 LEU C 570 4.185 37.980 28.494 1.00 29.75 C ATOM 1454 N SER C 571 1.719 36.524 23.768 1.00 34.59 N ATOM 1455 CA SER C 571 0.726 35.710 23.039 1.00 37.54 C ATOM 1456 C SER C 571 1.233 34.361 22.524 1.00 39.10 C ATOM 1457 O SER C 571 0.472 33.408 22.439 1.00 39.99 O ATOM 1458 CB SER C 571 0.110 36.490 21.870 1.00 36.69 C ATOM 1459 OG SER C 571 0.997 36.588 20.751 1.00 38.35 O ATOM 1460 N SER C 572 2.512 34.277 22.194 1.00 41.56 N ATOM 1461 CA SER C 572 3.050 33.101 21.512 1.00 44.03 C ATOM 1462 C SER C 572 3.897 32.192 22.407 1.00 45.50 C ATOM 1463 O SER C 572 4.640 31.334 21.920 1.00 46.36 O ATOM 1464 CB SER C 572 3.850 33.533 20.282 1.00 43.78 C ATOM 1465 OG SER C 572 4.864 34.442 20.648 1.00 45.79 O ATOM 1466 N SER C 573 3.780 32.373 23.714 1.00 46.95 N ATOM 1467 CA SER C 573 4.464 31.506 24.669 1.00 48.42 C ATOM 1468 C SER C 573 3.599 31.265 25.906 1.00 48.96 C ATOM 1469 O SER C 573 2.579 31.935 26.094 1.00 49.21 O ATOM 1470 CB SER C 573 5.849 32.072 25.039 1.00 48.70 C ATOM 1471 OG SER C 573 5.818 33.470 25.311 1.00 50.22 O ATOM 1472 N SER C 574 3.991 30.280 26.715 1.00 49.79 N ATOM 1473 CA SER C 574 3.365 29.998 28.010 1.00 50.39 C ATOM 1474 C SER C 574 4.433 30.203 29.077 1.00 50.23 C ATOM 1475 O SER C 574 5.620 30.136 28.754 1.00 50.10 O ATOM 1476 CB SER C 574 2.873 28.557 28.052 1.00 50.83 C ATOM 1477 OG SER C 574 3.909 27.662 27.646 1.00 53.12 O ATOM 1478 N ARG C 575 4.035 30.432 30.331 1.00 49.67 N ATOM 1479 CA ARG C 575 5.007 30.745 31.386 1.00 49.90 C ATOM 1480 C ARG C 575 6.081 29.679 31.596 1.00 50.67 C ATOM 1481 O ARG C 575 7.183 29.987 32.044 1.00 50.43 O ATOM 1482 CB ARG C 575 4.332 31.037 32.722 1.00 49.60 C ATOM 1483 CG ARG C 575 3.439 32.224 32.710 1.00 48.97 C ATOM 1484 CD ARG C 575 3.333 32.837 34.071 1.00 48.08 C ATOM 1485 NE ARG C 575 2.434 33.982 34.005 1.00 48.78 N ATOM 1486 CZ ARG C 575 2.310 34.906 34.950 1.00 47.48 C ATOM 1487 NH1 ARG C 575 3.044 34.829 36.061 1.00 46.65 N ATOM 1488 NH2 ARG C 575 1.451 35.913 34.772 1.00 46.67 N ATOM 1489 N GLU C 576 5.744 28.431 31.270 1.00 51.40 N ATOM 1490 CA GLU C 576 6.631 27.275 31.426 1.00 51.94 C ATOM 1491 C GLU C 576 7.790 27.332 30.423 1.00 51.62 C ATOM 1492 O GLU C 576 8.824 26.690 30.615 1.00 51.29 O ATOM 1493 CB GLU C 576 5.826 25.979 31.240 1.00 52.69 C ATOM 1494 CG GLU C 576 4.568 25.879 32.138 1.00 56.25 C ATOM 1495 CD GLU C 576 3.343 26.652 31.591 1.00 60.72 C ATOM 1496 OE1 GLU C 576 2.896 26.362 30.452 1.00 62.87 O ATOM 1497 OE2 GLU C 576 2.815 27.538 32.309 1.00 61.52 O ATOM 1498 N GLN C 577 7.601 28.110 29.357 1.00 51.02 N ATOM 1499 CA GLN C 577 8.618 28.322 28.331 1.00 50.72 C ATOM 1500 C GLN C 577 9.620 29.417 28.694 1.00 48.83 C ATOM 1501 O GLN C 577 10.664 29.521 28.053 1.00 49.08 O ATOM 1502 CB GLN C 577 7.960 28.713 27.005 1.00 51.07 C ATOM 1503 CG GLN C 577 7.195 27.605 26.279 1.00 52.74 C ATOM 1504 CD GLN C 577 6.605 28.093 24.952 1.00 53.52 C ATOM 1505 OE1 GLN C 577 7.125 29.027 24.328 1.00 57.21 O ATOM 1506 NE2 GLN C 577 5.520 27.456 24.514 1.00 57.43 N ATOM 1507 N TRP C 578 9.289 30.251 29.686 1.00 46.58 N ATOM 1508 CA TRP C 578 10.106 31.431 30.009 1.00 43.75 C ATOM 1509 C TRP C 578 11.426 31.008 30.643 1.00 43.16 C ATOM 1510 O TRP C 578 11.437 30.179 31.547 1.00 43.86 O ATOM 1511 CB TRP C 578 9.379 32.401 30.948 1.00 41.69 C ATOM 1512 CG TRP C 578 8.085 32.998 30.438 1.00 39.48 C ATOM 1513 CD1 TRP C 578 7.560 32.901 29.180 1.00 38.59 C ATOM 1514 CD2 TRP C 578 7.174 33.808 31.186 1.00 37.79 C ATOM 1515 NE1 TRP C 578 6.371 33.587 29.102 1.00 38.05 N ATOM 1516 CE2 TRP C 578 6.109 34.152 30.321 1.00 39.25 C ATOM 1517 CE3 TRP C 578 7.149 34.271 32.509 1.00 35.32 C ATOM 1518 CZ2 TRP C 578 5.028 34.940 30.739 1.00 39.67 C ATOM 1519 CZ3 TRP C 578 6.078 35.034 32.925 1.00 37.86 C ATOM 1520 CH2 TRP C 578 5.034 35.374 32.040 1.00 38.23 C ATOM 1521 N THR C 579 12.515 31.609 30.165 1.00 41.96 N ATOM 1522 CA THR C 579 13.877 31.282 30.543 1.00 40.57 C ATOM 1523 C THR C 579 14.307 32.058 31.784 1.00 39.91 C ATOM 1524 O THR C 579 14.516 33.273 31.719 1.00 38.77 O ATOM 1525 CB THR C 579 14.832 31.620 29.372 1.00 40.47 C ATOM 1526 OG1 THR C 579 14.356 30.983 28.192 1.00 40.16 O ATOM 1527 CG2 THR C 579 16.239 31.147 29.643 1.00 40.39 C ATOM 1528 N PRO C 580 14.441 31.363 32.925 1.00 39.81 N ATOM 1529 CA PRO C 580 14.915 32.075 34.126 1.00 39.78 C ATOM 1530 C PRO C 580 16.328 32.618 33.909 1.00 39.52 C ATOM 1531 O PRO C 580 17.187 31.905 33.376 1.00 39.46 O ATOM 1532 CB PRO C 580 14.877 31.012 35.237 1.00 39.83 C ATOM 1533 CG PRO C 580 14.718 29.670 34.517 1.00 40.36 C ATOM 1534 CD PRO C 580 14.164 29.926 33.156 1.00 39.79 C ATOM 1535 N SER C 581 16.537 33.887 34.258 1.00 39.16 N ATOM 1536 CA SER C 581 17.833 34.514 34.110 1.00 38.83 C ATOM 1537 C SER C 581 18.088 35.710 35.031 1.00 38.12 C ATOM 1538 O SER C 581 17.247 36.083 35.841 1.00 38.08 O ATOM 1539 CB SER C 581 18.101 34.901 32.644 1.00 40.17 C ATOM 1540 OG SER C 581 17.022 35.571 32.043 1.00 40.96 O ATOM 1541 N HIS C 582 19.279 36.286 34.903 1.00 36.85 N ATOM 1542 CA HIS C 582 19.606 37.551 35.538 1.00 36.48 C ATOM 1543 C HIS C 582 20.437 38.344 34.550 1.00 35.76 C ATOM 1544 O HIS C 582 21.039 37.774 33.625 1.00 34.53 O ATOM 1545 CB HIS C 582 20.340 37.346 36.878 1.00 37.52 C ATOM 1546 CG HIS C 582 21.606 36.554 36.759 1.00 40.19 C ATOM 1547 ND1 HIS C 582 22.852 37.113 36.958 1.00 43.05 N ATOM 1548 CD2 HIS C 582 21.819 35.255 36.436 1.00 41.72 C ATOM 1549 CE1 HIS C 582 23.778 36.190 36.754 1.00 44.76 C ATOM 1550 NE2 HIS C 582 23.178 35.052 36.442 1.00 42.86 N ATOM 1551 N VAL C 583 20.429 39.660 34.732 1.00 34.74 N ATOM 1552 CA VAL C 583 21.119 40.559 33.863 1.00 34.43 C ATOM 1553 C VAL C 583 22.301 41.117 34.628 1.00 35.57 C ATOM 1554 O VAL C 583 22.157 41.635 35.723 1.00 36.23 O ATOM 1555 CB VAL C 583 20.184 41.693 33.301 1.00 33.95 C ATOM 1556 CG1 VAL C 583 20.910 42.540 32.288 1.00 33.34 C ATOM 1557 CG2 VAL C 583 18.921 41.107 32.666 1.00 31.50 C ATOM 1558 N SER C 584 23.483 40.951 34.052 1.00 36.16 N ATOM 1559 CA SER C 584 24.658 41.628 34.525 1.00 36.94 C ATOM 1560 C SER C 584 24.654 42.985 33.851 1.00 36.17 C ATOM 1561 O SER C 584 24.819 43.089 32.638 1.00 35.52 O ATOM 1562 CB SER C 584 25.914 40.849 34.131 1.00 37.67 C ATOM 1563 OG SER C 584 27.016 41.338 34.855 1.00 41.79 O ATOM 1564 N VAL C 585 24.437 44.023 34.650 1.00 36.28 N ATOM 1565 CA VAL C 585 24.296 45.377 34.140 1.00 35.91 C ATOM 1566 C VAL C 585 25.600 46.144 34.358 1.00 36.59 C ATOM 1567 O VAL C 585 26.106 46.205 35.458 1.00 36.91 O ATOM 1568 CB VAL C 585 23.114 46.129 34.844 1.00 35.76 C ATOM 1569 CG1 VAL C 585 23.008 47.559 34.346 1.00 34.46 C ATOM 1570 CG2 VAL C 585 21.792 45.395 34.656 1.00 34.20 C ATOM 1571 N ALA C 586 26.145 46.721 33.297 1.00 37.49 N ATOM 1572 CA ALA C 586 27.313 47.576 33.422 1.00 37.74 C ATOM 1573 C ALA C 586 27.133 48.769 32.489 1.00 37.81 C ATOM 1574 O ALA C 586 26.402 48.663 31.501 1.00 37.58 O ATOM 1575 CB ALA C 586 28.583 46.789 33.069 1.00 37.62 C ATOM 1576 N PRO C 587 27.786 49.914 32.796 1.00 37.76 N ATOM 1577 CA PRO C 587 27.736 51.045 31.865 1.00 37.13 C ATOM 1578 C PRO C 587 28.067 50.678 30.414 1.00 36.60 C ATOM 1579 O PRO C 587 27.408 51.176 29.517 1.00 36.55 O ATOM 1580 CB PRO C 587 28.740 52.036 32.451 1.00 37.44 C ATOM 1581 CG PRO C 587 28.739 51.744 33.906 1.00 38.36 C ATOM 1582 CD PRO C 587 28.535 50.248 34.026 1.00 38.19 C ATOM 1583 N ALA C 588 29.039 49.791 30.178 1.00 36.20 N ATOM 1584 CA ALA C 588 29.343 49.372 28.801 1.00 34.70 C ATOM 1585 C ALA C 588 28.321 48.409 28.202 1.00 33.81 C ATOM 1586 O ALA C 588 27.939 48.572 27.047 1.00 33.53 O ATOM 1587 CB ALA C 588 30.771 48.772 28.684 1.00 35.15 C ATOM 1588 N THR C 589 27.916 47.402 28.975 1.00 33.11 N ATOM 1589 CA THR C 589 27.145 46.285 28.437 1.00 34.03 C ATOM 1590 C THR C 589 26.091 45.735 29.372 1.00 32.69 C ATOM 1591 O THR C 589 26.227 45.777 30.584 1.00 32.10 O ATOM 1592 CB THR C 589 28.067 45.033 28.082 1.00 34.15 C ATOM 1593 OG1 THR C 589 28.670 44.559 29.291 1.00 36.03 O ATOM 1594 CG2 THR C 589 29.139 45.388 27.080 1.00 33.40 C ATOM 1595 N LEU C 590 25.053 45.170 28.775 1.00 32.43 N ATOM 1596 CA LEU C 590 24.135 44.325 29.513 1.00 32.06 C ATOM 1597 C LEU C 590 24.378 42.880 29.077 1.00 31.95 C ATOM 1598 O LEU C 590 24.449 42.598 27.885 1.00 32.93 O ATOM 1599 CB LEU C 590 22.685 44.725 29.198 1.00 32.10 C ATOM 1600 CG LEU C 590 22.317 46.210 29.272 1.00 32.16 C ATOM 1601 CD1 LEU C 590 20.869 46.382 28.861 1.00 31.77 C ATOM 1602 CD2 LEU C 590 22.571 46.779 30.695 1.00 32.46 C ATOM 1603 N THR C 591 24.493 41.963 30.021 1.00 31.51 N ATOM 1604 CA THR C 591 24.640 40.564 29.643 1.00 31.79 C ATOM 1605 C THR C 591 23.521 39.757 30.234 1.00 31.45 C ATOM 1606 O THR C 591 23.367 39.689 31.436 1.00 31.74 O ATOM 1607 CB THR C 591 26.002 39.965 30.087 1.00 31.68 C ATOM 1608 OG1 THR C 591 27.030 40.874 29.725 1.00 32.24 O ATOM 1609 CG2 THR C 591 26.247 38.643 29.389 1.00 31.20 C ATOM 1610 N ILE C 592 22.725 39.158 29.360 1.00 31.69 N ATOM 1611 CA ILE C 592 21.650 38.313 29.800 1.00 32.31 C ATOM 1612 C ILE C 592 22.245 36.900 29.995 1.00 33.41 C ATOM 1613 O ILE C 592 22.787 36.326 29.055 1.00 32.42 O ATOM 1614 CB ILE C 592 20.510 38.290 28.754 1.00 31.96 C ATOM 1615 CG1 ILE C 592 20.098 39.724 28.365 1.00 32.05 C ATOM 1616 CG2 ILE C 592 19.353 37.443 29.271 1.00 32.40 C ATOM 1617 CD1 ILE C 592 19.350 39.840 27.013 1.00 31.60 C ATOM 1618 N LEU C 593 22.100 36.356 31.199 1.00 34.87 N ATOM 1619 CA LEU C 593 22.717 35.091 31.586 1.00 36.99 C ATOM 1620 C LEU C 593 21.662 34.113 32.083 1.00 38.27 C ATOM 1621 O LEU C 593 20.822 34.472 32.923 1.00 37.76 O ATOM 1622 CB LEU C 593 23.749 35.323 32.712 1.00 37.21 C ATOM 1623 CG LEU C 593 24.948 36.235 32.410 1.00 38.26 C ATOM 1624 CD1 LEU C 593 25.518 36.861 33.690 1.00 40.03 C ATOM 1625 CD2 LEU C 593 26.011 35.507 31.616 1.00 38.46 C ATOM 1626 N HIS C 594 21.709 32.877 31.575 1.00 39.73 N ATOM 1627 CA HIS C 594 20.843 31.809 32.090 1.00 41.31 C ATOM 1628 C HIS C 594 21.045 31.647 33.597 1.00 42.80 C ATOM 1629 O HIS C 594 22.157 31.781 34.085 1.00 42.95 O ATOM 1630 CB HIS C 594 21.091 30.481 31.363 1.00 40.33 C ATOM 1631 CG HIS C 594 19.905 29.563 31.364 1.00 39.70 C ATOM 1632 ND1 HIS C 594 19.441 28.940 32.503 1.00 39.15 N ATOM 1633 CD2 HIS C 594 19.092 29.159 30.359 1.00 38.99 C ATOM 1634 CE1 HIS C 594 18.396 28.192 32.200 1.00 38.91 C ATOM 1635 NE2 HIS C 594 18.161 28.311 30.905 1.00 39.33 N ATOM 1636 N GLN C 595 19.961 31.365 34.312 1.00 44.96 N ATOM 1637 CA GLN C 595 19.942 31.297 35.773 1.00 47.49 C ATOM 1638 C GLN C 595 21.090 30.499 36.429 1.00 49.85 C ATOM 1639 O GLN C 595 21.891 31.068 37.206 1.00 51.05 O ATOM 1640 CB GLN C 595 18.569 30.791 36.269 1.00 46.93 C ATOM 1641 CG GLN C 595 18.552 30.308 37.728 1.00 47.28 C ATOM 1642 CD GLN C 595 17.152 29.992 38.257 1.00 47.58 C ATOM 1643 OE1 GLN C 595 16.532 28.970 37.904 1.00 46.34 O ATOM 1644 NE2 GLN C 595 16.655 30.868 39.121 1.00 47.14 N ATOM 1645 N GLN C 596 21.183 29.201 36.165 1.00 51.54 N ATOM 1646 CA GLN C 596 22.182 28.394 36.919 1.00 53.99 C ATOM 1647 C GLN C 596 23.509 28.264 36.165 1.00 53.15 C ATOM 1648 O GLN C 596 24.591 28.542 36.708 1.00 53.61 O ATOM 1649 CB GLN C 596 21.621 27.010 37.276 1.00 53.77 C ATOM 1650 CG GLN C 596 22.622 26.091 38.012 1.00 56.97 C ATOM 1651 CD GLN C 596 21.965 24.861 38.636 1.00 57.63 C ATOM 1652 OE1 GLN C 596 22.610 23.807 38.792 1.00 62.79 O ATOM 1653 NE2 GLN C 596 20.679 24.986 39.005 1.00 60.25 N ATOM 1654 N THR C 597 23.391 27.867 34.901 1.00 52.58 N ATOM 1655 CA THR C 597 24.518 27.600 34.018 1.00 51.65 C ATOM 1656 C THR C 597 25.358 28.836 33.684 1.00 50.95 C ATOM 1657 O THR C 597 26.501 28.707 33.225 1.00 51.03 O ATOM 1658 CB THR C 597 24.006 27.018 32.702 1.00 51.98 C ATOM 1659 OG1 THR C 597 23.227 28.013 32.024 1.00 51.99 O ATOM 1660 CG2 THR C 597 23.133 25.784 32.951 1.00 52.12 C ATOM 1661 N GLU C 598 24.788 30.027 33.898 1.00 49.43 N ATOM 1662 CA GLU C 598 25.404 31.307 33.496 1.00 47.45 C ATOM 1663 C GLU C 598 25.732 31.396 31.996 1.00 45.64 C ATOM 1664 O GLU C 598 26.610 32.158 31.592 1.00 45.10 O ATOM 1665 CB GLU C 598 26.638 31.644 34.347 1.00 48.14 C ATOM 1666 CG GLU C 598 26.425 31.497 35.870 1.00 50.52 C ATOM 1667 CD GLU C 598 25.513 32.566 36.479 1.00 52.02 C ATOM 1668 OE1 GLU C 598 25.640 33.750 36.105 1.00 52.54 O ATOM 1669 OE2 GLU C 598 24.683 32.215 37.351 1.00 53.27 O ATOM 1670 N ALA C 599 25.012 30.633 31.176 1.00 43.70 N ATOM 1671 CA ALA C 599 25.169 30.731 29.728 1.00 42.24 C ATOM 1672 C ALA C 599 24.730 32.115 29.213 1.00 41.14 C ATOM 1673 O ALA C 599 23.737 32.674 29.665 1.00 40.74 O ATOM 1674 CB ALA C 599 24.402 29.618 29.022 1.00 42.08 C ATOM 1675 N VAL C 600 25.492 32.663 28.278 1.00 39.83 N ATOM 1676 CA VAL C 600 25.215 33.980 27.756 1.00 38.91 C ATOM 1677 C VAL C 600 24.077 33.835 26.740 1.00 38.22 C ATOM 1678 O VAL C 600 24.196 33.121 25.741 1.00 37.67 O ATOM 1679 CB VAL C 600 26.493 34.621 27.182 1.00 38.81 C ATOM 1680 CG1 VAL C 600 26.223 35.994 26.555 1.00 38.85 C ATOM 1681 CG2 VAL C 600 27.561 34.725 28.283 1.00 39.49 C ATOM 1682 N LEU C 601 22.959 34.490 27.046 1.00 36.92 N ATOM 1683 CA LEU C 601 21.779 34.457 26.196 1.00 35.92 C ATOM 1684 C LEU C 601 21.756 35.675 25.290 1.00 35.10 C ATOM 1685 O LEU C 601 21.137 35.661 24.235 1.00 35.92 O ATOM 1686 CB LEU C 601 20.511 34.382 27.055 1.00 36.31 C ATOM 1687 CG LEU C 601 20.414 33.221 28.060 1.00 35.09 C ATOM 1688 CD1 LEU C 601 19.191 33.377 28.927 1.00 35.29 C ATOM 1689 CD2 LEU C 601 20.339 31.871 27.336 1.00 37.60 C ATOM 1690 N GLY C 602 22.449 36.723 25.697 1.00 33.96 N ATOM 1691 CA GLY C 602 22.630 37.887 24.847 1.00 33.96 C ATOM 1692 C GLY C 602 23.616 38.813 25.513 1.00 33.14 C ATOM 1693 O GLY C 602 23.800 38.750 26.715 1.00 33.14 O ATOM 1694 N GLU C 603 24.260 39.658 24.733 1.00 33.77 N ATOM 1695 CA GLU C 603 25.062 40.721 25.296 1.00 34.75 C ATOM 1696 C GLU C 603 24.828 41.926 24.439 1.00 34.12 C ATOM 1697 O GLU C 603 24.875 41.827 23.222 1.00 34.92 O ATOM 1698 CB GLU C 603 26.543 40.366 25.313 1.00 35.96 C ATOM 1699 CG GLU C 603 27.369 41.438 26.032 1.00 39.73 C ATOM 1700 CD GLU C 603 28.772 40.998 26.355 1.00 42.82 C ATOM 1701 OE1 GLU C 603 29.119 39.845 26.033 1.00 47.80 O ATOM 1702 OE2 GLU C 603 29.522 41.811 26.938 1.00 44.57 O ATOM 1703 N CYS C 604 24.537 43.058 25.077 1.00 33.04 N ATOM 1704 CA CYS C 604 24.102 44.256 24.367 1.00 32.17 C ATOM 1705 C CYS C 604 24.962 45.435 24.788 1.00 31.03 C ATOM 1706 O CYS C 604 25.149 45.636 25.957 1.00 31.37 O ATOM 1707 CB CYS C 604 22.623 44.531 24.693 1.00 32.27 C ATOM 1708 SG CYS C 604 21.513 43.133 24.319 1.00 33.34 S ATOM 1709 N ARG C 605 25.495 46.198 23.841 1.00 30.46 N ATOM 1710 CA ARG C 605 26.253 47.393 24.200 1.00 30.02 C ATOM 1711 C ARG C 605 25.290 48.546 24.570 1.00 29.83 C ATOM 1712 O ARG C 605 24.441 48.909 23.765 1.00 28.66 O ATOM 1713 CB ARG C 605 27.153 47.813 23.038 1.00 29.64 C ATOM 1714 CG ARG C 605 28.417 46.944 22.938 1.00 29.43 C ATOM 1715 CD ARG C 605 29.051 47.110 21.569 1.00 30.89 C ATOM 1716 NE ARG C 605 30.202 46.217 21.386 1.00 32.15 N ATOM 1717 CZ ARG C 605 31.442 46.466 21.806 1.00 30.99 C ATOM 1718 NH1 ARG C 605 31.748 47.604 22.456 1.00 29.10 N ATOM 1719 NH2 ARG C 605 32.389 45.571 21.556 1.00 30.11 N ATOM 1720 N VAL C 606 25.451 49.109 25.764 1.00 30.24 N ATOM 1721 CA VAL C 606 24.591 50.205 26.267 1.00 31.18 C ATOM 1722 C VAL C 606 24.549 51.387 25.302 1.00 31.85 C ATOM 1723 O VAL C 606 23.490 51.969 25.036 1.00 31.70 O ATOM 1724 CB VAL C 606 25.005 50.607 27.703 1.00 31.91 C ATOM 1725 CG1 VAL C 606 24.265 51.875 28.184 1.00 31.08 C ATOM 1726 CG2 VAL C 606 24.784 49.434 28.653 1.00 29.89 C ATOM 1727 N ARG C 607 25.685 51.694 24.690 1.00 31.63 N ATOM 1728 CA ARG C 607 25.723 52.731 23.667 1.00 32.14 C ATOM 1729 C ARG C 607 24.736 52.573 22.494 1.00 31.39 C ATOM 1730 O ARG C 607 24.348 53.582 21.873 1.00 31.47 O ATOM 1731 CB ARG C 607 27.164 52.876 23.162 1.00 33.18 C ATOM 1732 CG ARG C 607 27.352 53.784 21.974 1.00 37.70 C ATOM 1733 CD ARG C 607 28.594 53.361 21.213 1.00 45.40 C ATOM 1734 NE ARG C 607 28.674 54.015 19.909 1.00 52.84 N ATOM 1735 CZ ARG C 607 29.824 54.351 19.326 1.00 54.41 C ATOM 1736 NH1 ARG C 607 30.975 54.101 19.951 1.00 54.88 N ATOM 1737 NH2 ARG C 607 29.821 54.950 18.138 1.00 55.02 N ATOM 1738 N PHE C 608 24.356 51.338 22.151 1.00 30.27 N ATOM 1739 CA PHE C 608 23.374 51.122 21.057 1.00 29.59 C ATOM 1740 C PHE C 608 21.972 50.770 21.541 1.00 28.33 C ATOM 1741 O PHE C 608 21.122 50.389 20.766 1.00 27.90 O ATOM 1742 CB PHE C 608 23.889 50.073 20.062 1.00 30.49 C ATOM 1743 CG PHE C 608 25.148 50.511 19.376 1.00 32.47 C ATOM 1744 CD1 PHE C 608 25.088 51.392 18.309 1.00 31.38 C ATOM 1745 CD2 PHE C 608 26.398 50.097 19.855 1.00 35.76 C ATOM 1746 CE1 PHE C 608 26.260 51.846 17.685 1.00 35.86 C ATOM 1747 CE2 PHE C 608 27.580 50.529 19.233 1.00 36.83 C ATOM 1748 CZ PHE C 608 27.505 51.412 18.145 1.00 33.66 C ATOM 1749 N LEU C 609 21.752 50.889 22.841 1.00 27.82 N ATOM 1750 CA LEU C 609 20.394 50.794 23.393 1.00 27.12 C ATOM 1751 C LEU C 609 19.678 52.134 23.152 1.00 26.24 C ATOM 1752 O LEU C 609 20.107 53.157 23.661 1.00 27.41 O ATOM 1753 CB LEU C 609 20.501 50.429 24.878 1.00 25.76 C ATOM 1754 CG LEU C 609 19.215 50.024 25.623 1.00 26.91 C ATOM 1755 CD1 LEU C 609 19.595 49.156 26.779 1.00 23.38 C ATOM 1756 CD2 LEU C 609 18.475 51.311 26.095 1.00 24.23 C ATOM 1757 N SER C 610 18.619 52.155 22.359 1.00 25.61 N ATOM 1758 CA SER C 610 17.964 53.420 22.082 1.00 26.22 C ATOM 1759 C SER C 610 16.870 53.808 23.128 1.00 25.69 C ATOM 1760 O SER C 610 16.636 54.991 23.389 1.00 25.70 O ATOM 1761 CB SER C 610 17.373 53.410 20.676 1.00 24.95 C ATOM 1762 OG SER C 610 16.750 52.173 20.428 1.00 27.56 O ATOM 1763 N PHE C 611 16.230 52.806 23.722 1.00 26.03 N ATOM 1764 CA PHE C 611 15.005 53.042 24.507 1.00 25.14 C ATOM 1765 C PHE C 611 14.751 51.892 25.455 1.00 24.38 C ATOM 1766 O PHE C 611 15.038 50.757 25.130 1.00 24.17 O ATOM 1767 CB PHE C 611 13.810 53.217 23.543 1.00 24.56 C ATOM 1768 CG PHE C 611 12.516 53.642 24.220 1.00 25.82 C ATOM 1769 CD1 PHE C 611 12.322 54.973 24.634 1.00 22.58 C ATOM 1770 CD2 PHE C 611 11.483 52.724 24.399 1.00 25.05 C ATOM 1771 CE1 PHE C 611 11.126 55.363 25.247 1.00 25.72 C ATOM 1772 CE2 PHE C 611 10.253 53.124 25.021 1.00 26.04 C ATOM 1773 CZ PHE C 611 10.100 54.435 25.438 1.00 21.58 C ATOM 1774 N LEU C 612 14.177 52.195 26.623 1.00 23.41 N ATOM 1775 CA LEU C 612 13.710 51.163 27.533 1.00 22.92 C ATOM 1776 C LEU C 612 12.411 51.629 28.213 1.00 22.73 C ATOM 1777 O LEU C 612 12.159 52.840 28.324 1.00 22.73 O ATOM 1778 CB LEU C 612 14.793 50.848 28.581 1.00 21.84 C ATOM 1779 CG LEU C 612 15.265 52.030 29.423 1.00 25.05 C ATOM 1780 CD1 LEU C 612 14.444 52.056 30.715 1.00 28.37 C ATOM 1781 CD2 LEU C 612 16.725 51.875 29.750 1.00 26.65 C ATOM 1782 N ALA C 613 11.628 50.674 28.698 1.00 23.67 N ATOM 1783 CA ALA C 613 10.353 50.971 29.364 1.00 23.56 C ATOM 1784 C ALA C 613 9.865 49.762 30.150 1.00 24.11 C ATOM 1785 O ALA C 613 10.269 48.619 29.882 1.00 24.18 O ATOM 1786 CB ALA C 613 9.284 51.400 28.318 1.00 22.39 C ATOM 1787 N VAL C 614 8.998 50.040 31.129 1.00 24.04 N ATOM 1788 CA VAL C 614 8.177 49.042 31.771 1.00 23.69 C ATOM 1789 C VAL C 614 6.883 48.991 30.965 1.00 23.63 C ATOM 1790 O VAL C 614 6.368 50.029 30.566 1.00 24.99 O ATOM 1791 CB VAL C 614 7.922 49.413 33.252 1.00 23.93 C ATOM 1792 CG1 VAL C 614 6.899 48.441 33.927 1.00 21.15 C ATOM 1793 CG2 VAL C 614 9.257 49.428 34.027 1.00 22.70 C ATOM 1794 N GLY C 615 6.384 47.795 30.677 1.00 23.52 N ATOM 1795 CA GLY C 615 5.124 47.649 29.961 1.00 22.69 C ATOM 1796 C GLY C 615 3.915 48.137 30.770 1.00 23.28 C ATOM 1797 O GLY C 615 4.025 48.547 31.935 1.00 22.05 O ATOM 1798 N ARG C 616 2.741 48.068 30.164 1.00 23.48 N ATOM 1799 CA ARG C 616 1.525 48.458 30.886 1.00 25.24 C ATOM 1800 C ARG C 616 1.250 47.529 32.075 1.00 25.67 C ATOM 1801 O ARG C 616 0.769 47.973 33.110 1.00 26.40 O ATOM 1802 CB ARG C 616 0.340 48.518 29.927 1.00 25.07 C ATOM 1803 CG ARG C 616 0.528 49.576 28.844 1.00 24.86 C ATOM 1804 CD ARG C 616 0.755 50.955 29.432 1.00 25.86 C ATOM 1805 NE ARG C 616 0.897 51.933 28.350 1.00 29.27 N ATOM 1806 CZ ARG C 616 1.031 53.248 28.515 1.00 26.77 C ATOM 1807 NH1 ARG C 616 1.053 53.798 29.716 1.00 26.29 N ATOM 1808 NH2 ARG C 616 1.176 54.006 27.459 1.00 31.27 N ATOM 1809 N ASP C 617 1.561 46.250 31.896 1.00 26.07 N ATOM 1810 CA ASP C 617 1.757 45.328 33.005 1.00 27.41 C ATOM 1811 C ASP C 617 3.143 45.528 33.615 1.00 27.50 C ATOM 1812 O ASP C 617 4.191 45.333 32.969 1.00 27.36 O ATOM 1813 CB ASP C 617 1.574 43.894 32.568 1.00 26.74 C ATOM 1814 CG ASP C 617 1.569 42.914 33.750 1.00 29.82 C ATOM 1815 OD1 ASP C 617 2.555 42.839 34.509 1.00 30.28 O ATOM 1816 OD2 ASP C 617 0.572 42.189 33.899 1.00 31.69 O ATOM 1817 N VAL C 618 3.094 45.898 34.881 1.00 27.85 N ATOM 1818 CA VAL C 618 4.233 46.279 35.716 1.00 29.00 C ATOM 1819 C VAL C 618 5.331 45.195 35.896 1.00 28.29 C ATOM 1820 O VAL C 618 6.456 45.500 36.296 1.00 28.02 O ATOM 1821 CB VAL C 618 3.679 46.776 37.081 1.00 29.39 C ATOM 1822 CG1 VAL C 618 3.432 45.567 38.047 1.00 31.31 C ATOM 1823 CG2 VAL C 618 4.569 47.785 37.679 1.00 32.89 C ATOM 1824 N HIS C 619 5.016 43.951 35.575 1.00 28.23 N ATOM 1825 CA HIS C 619 6.026 42.893 35.597 1.00 29.46 C ATOM 1826 C HIS C 619 6.970 42.990 34.405 1.00 28.82 C ATOM 1827 O HIS C 619 8.070 42.447 34.443 1.00 28.54 O ATOM 1828 CB HIS C 619 5.373 41.524 35.601 1.00 28.85 C ATOM 1829 CG HIS C 619 4.542 41.258 36.815 1.00 31.33 C ATOM 1830 ND1 HIS C 619 3.195 41.550 36.870 1.00 31.25 N ATOM 1831 CD2 HIS C 619 4.866 40.748 38.028 1.00 31.63 C ATOM 1832 CE1 HIS C 619 2.720 41.222 38.058 1.00 32.10 C ATOM 1833 NE2 HIS C 619 3.711 40.729 38.777 1.00 33.21 N ATOM 1834 N THR C 620 6.534 43.684 33.352 1.00 28.06 N ATOM 1835 CA THR C 620 7.239 43.604 32.071 1.00 27.55 C ATOM 1836 C THR C 620 8.284 44.679 31.936 1.00 26.96 C ATOM 1837 O THR C 620 8.076 45.825 32.304 1.00 27.72 O ATOM 1838 CB THR C 620 6.277 43.621 30.823 1.00 27.20 C ATOM 1839 OG1 THR C 620 5.500 44.819 30.830 1.00 26.64 O ATOM 1840 CG2 THR C 620 5.360 42.400 30.788 1.00 26.82 C ATOM 1841 N PHE C 621 9.425 44.297 31.382 1.00 27.14 N ATOM 1842 CA PHE C 621 10.488 45.245 31.045 1.00 25.91 C ATOM 1843 C PHE C 621 10.952 44.965 29.614 1.00 24.97 C ATOM 1844 O PHE C 621 10.953 43.834 29.172 1.00 24.43 O ATOM 1845 CB PHE C 621 11.676 45.122 32.021 1.00 25.96 C ATOM 1846 CG PHE C 621 12.862 45.990 31.634 1.00 26.04 C ATOM 1847 CD1 PHE C 621 12.720 47.368 31.543 1.00 25.18 C ATOM 1848 CD2 PHE C 621 14.090 45.418 31.309 1.00 26.95 C ATOM 1849 CE1 PHE C 621 13.800 48.192 31.162 1.00 26.01 C ATOM 1850 CE2 PHE C 621 15.184 46.226 30.933 1.00 26.76 C ATOM 1851 CZ PHE C 621 15.037 47.617 30.860 1.00 24.28 C ATOM 1852 N ALA C 622 11.311 46.007 28.878 1.00 25.26 N ATOM 1853 CA ALA C 622 11.846 45.825 27.537 1.00 25.01 C ATOM 1854 C ALA C 622 12.789 46.955 27.204 1.00 25.13 C ATOM 1855 O ALA C 622 12.623 48.073 27.702 1.00 24.94 O ATOM 1856 CB ALA C 622 10.696 45.764 26.489 1.00 25.33 C ATOM 1857 N PHE C 623 13.799 46.643 26.380 1.00 24.62 N ATOM 1858 CA PHE C 623 14.649 47.644 25.786 1.00 25.10 C ATOM 1859 C PHE C 623 14.826 47.376 24.293 1.00 25.70 C ATOM 1860 O PHE C 623 14.797 46.235 23.828 1.00 25.57 O ATOM 1861 CB PHE C 623 16.003 47.833 26.528 1.00 24.31 C ATOM 1862 CG PHE C 623 16.909 46.594 26.518 1.00 26.14 C ATOM 1863 CD1 PHE C 623 17.823 46.372 25.456 1.00 25.22 C ATOM 1864 CD2 PHE C 623 16.882 45.686 27.586 1.00 24.78 C ATOM 1865 CE1 PHE C 623 18.679 45.229 25.449 1.00 26.29 C ATOM 1866 CE2 PHE C 623 17.733 44.546 27.589 1.00 25.97 C ATOM 1867 CZ PHE C 623 18.639 44.331 26.510 1.00 26.31 C ATOM 1868 N ILE C 624 14.986 48.460 23.555 1.00 26.45 N ATOM 1869 CA ILE C 624 15.193 48.387 22.129 1.00 27.11 C ATOM 1870 C ILE C 624 16.660 48.656 21.876 1.00 28.35 C ATOM 1871 O ILE C 624 17.258 49.537 22.491 1.00 28.27 O ATOM 1872 CB ILE C 624 14.363 49.433 21.398 1.00 26.92 C ATOM 1873 CG1 ILE C 624 12.841 49.183 21.694 1.00 26.36 C ATOM 1874 CG2 ILE C 624 14.715 49.396 19.887 1.00 26.92 C ATOM 1875 CD1 ILE C 624 11.917 50.302 21.183 1.00 26.72 C ATOM 1876 N MET C 625 17.230 47.841 20.996 1.00 29.97 N ATOM 1877 CA MET C 625 18.625 47.924 20.604 1.00 29.53 C ATOM 1878 C MET C 625 18.645 48.370 19.149 1.00 30.41 C ATOM 1879 O MET C 625 17.854 47.894 18.333 1.00 30.21 O ATOM 1880 CB MET C 625 19.269 46.543 20.692 1.00 29.59 C ATOM 1881 CG MET C 625 19.609 46.043 22.071 1.00 27.25 C ATOM 1882 SD MET C 625 20.624 47.163 23.025 1.00 29.71 S ATOM 1883 CE MET C 625 22.140 47.105 21.982 1.00 30.21 C ATOM 1884 N ALA C 626 19.526 49.311 18.821 1.00 31.62 N ATOM 1885 CA ALA C 626 19.806 49.595 17.416 1.00 32.10 C ATOM 1886 C ALA C 626 20.790 48.497 16.983 1.00 33.12 C ATOM 1887 O ALA C 626 21.981 48.579 17.256 1.00 31.76 O ATOM 1888 CB ALA C 626 20.424 50.976 17.271 1.00 31.36 C ATOM 1889 N ALA C 627 20.269 47.440 16.378 1.00 34.97 N ATOM 1890 CA ALA C 627 21.105 46.307 15.974 1.00 37.09 C ATOM 1891 C ALA C 627 21.910 46.722 14.748 1.00 38.33 C ATOM 1892 O ALA C 627 22.963 46.155 14.452 1.00 38.85 O ATOM 1893 CB ALA C 627 20.245 45.074 15.693 1.00 36.50 C ATOM 1894 N GLY C 628 21.399 47.741 14.058 1.00 39.23 N ATOM 1895 CA GLY C 628 22.090 48.413 12.967 1.00 40.19 C ATOM 1896 C GLY C 628 21.466 49.789 12.727 1.00 41.26 C ATOM 1897 O GLY C 628 20.460 50.138 13.350 1.00 41.21 O ATOM 1898 N PRO C 629 22.053 50.577 11.815 1.00 41.92 N ATOM 1899 CA PRO C 629 21.582 51.937 11.525 1.00 42.41 C ATOM 1900 C PRO C 629 20.060 52.036 11.360 1.00 42.72 C ATOM 1901 O PRO C 629 19.454 53.002 11.811 1.00 43.62 O ATOM 1902 CB PRO C 629 22.281 52.286 10.200 1.00 43.09 C ATOM 1903 CG PRO C 629 23.475 51.403 10.122 1.00 42.16 C ATOM 1904 CD PRO C 629 23.226 50.193 11.001 1.00 42.04 C ATOM 1905 N ALA C 630 19.450 51.040 10.736 1.00 42.39 N ATOM 1906 CA ALA C 630 18.032 51.088 10.444 1.00 42.16 C ATOM 1907 C ALA C 630 17.411 49.750 10.798 1.00 41.53 C ATOM 1908 O ALA C 630 16.504 49.277 10.123 1.00 41.90 O ATOM 1909 CB ALA C 630 17.806 51.403 8.944 1.00 43.45 C ATOM 1910 N SER C 631 17.941 49.120 11.838 1.00 40.12 N ATOM 1911 CA SER C 631 17.445 47.840 12.271 1.00 39.07 C ATOM 1912 C SER C 631 17.388 47.778 13.806 1.00 37.82 C ATOM 1913 O SER C 631 18.378 48.024 14.479 1.00 36.90 O ATOM 1914 CB SER C 631 18.330 46.731 11.721 1.00 39.11 C ATOM 1915 OG SER C 631 17.811 45.485 12.137 1.00 41.00 O ATOM 1916 N PHE C 632 16.211 47.440 14.333 1.00 36.61 N ATOM 1917 CA PHE C 632 15.913 47.548 15.763 1.00 35.18 C ATOM 1918 C PHE C 632 15.394 46.233 16.317 1.00 34.33 C ATOM 1919 O PHE C 632 14.584 45.575 15.682 1.00 34.58 O ATOM 1920 CB PHE C 632 14.933 48.706 15.988 1.00 34.12 C ATOM 1921 CG PHE C 632 15.421 49.996 15.404 1.00 35.22 C ATOM 1922 CD1 PHE C 632 16.488 50.680 15.991 1.00 34.42 C ATOM 1923 CD2 PHE C 632 14.878 50.487 14.223 1.00 34.73 C ATOM 1924 CE1 PHE C 632 16.973 51.843 15.431 1.00 34.75 C ATOM 1925 CE2 PHE C 632 15.351 51.633 13.656 1.00 33.10 C ATOM 1926 CZ PHE C 632 16.406 52.324 14.255 1.00 34.25 C ATOM 1927 N CYS C 633 15.883 45.868 17.501 1.00 33.33 N ATOM 1928 CA CYS C 633 15.533 44.627 18.169 1.00 31.54 C ATOM 1929 C CYS C 633 15.110 44.892 19.626 1.00 30.19 C ATOM 1930 O CYS C 633 15.844 45.549 20.384 1.00 29.59 O ATOM 1931 CB CYS C 633 16.731 43.699 18.138 1.00 31.40 C ATOM 1932 SG CYS C 633 16.479 42.116 18.869 1.00 34.76 S ATOM 1933 N CYS C 634 13.932 44.381 19.991 1.00 28.08 N ATOM 1934 CA CYS C 634 13.360 44.570 21.317 1.00 27.24 C ATOM 1935 C CYS C 634 13.529 43.308 22.182 1.00 25.86 C ATOM 1936 O CYS C 634 13.077 42.233 21.815 1.00 25.58 O ATOM 1937 CB CYS C 634 11.885 44.965 21.212 1.00 27.35 C ATOM 1938 SG CYS C 634 11.131 45.293 22.855 1.00 26.66 S ATOM 1939 N HIS C 635 14.240 43.465 23.291 1.00 25.40 N ATOM 1940 CA HIS C 635 14.527 42.409 24.265 1.00 25.28 C ATOM 1941 C HIS C 635 13.577 42.543 25.468 1.00 24.79 C ATOM 1942 O HIS C 635 13.426 43.634 26.044 1.00 25.20 O ATOM 1943 CB HIS C 635 15.990 42.541 24.766 1.00 25.24 C ATOM 1944 CG HIS C 635 17.022 42.228 23.724 1.00 27.59 C ATOM 1945 ND1 HIS C 635 17.658 41.003 23.651 1.00 29.18 N ATOM 1946 CD2 HIS C 635 17.529 42.976 22.718 1.00 27.90 C ATOM 1947 CE1 HIS C 635 18.502 41.008 22.634 1.00 28.87 C ATOM 1948 NE2 HIS C 635 18.450 42.197 22.057 1.00 28.96 N ATOM 1949 N MET C 636 12.997 41.437 25.891 1.00 25.72 N ATOM 1950 CA MET C 636 11.842 41.488 26.799 1.00 26.84 C ATOM 1951 C MET C 636 11.962 40.548 27.969 1.00 27.24 C ATOM 1952 O MET C 636 12.532 39.468 27.831 1.00 27.57 O ATOM 1953 CB MET C 636 10.565 41.198 26.011 1.00 25.37 C ATOM 1954 CG MET C 636 10.211 42.335 25.087 1.00 27.14 C ATOM 1955 SD MET C 636 9.050 41.855 23.815 1.00 29.14 S ATOM 1956 CE MET C 636 9.894 40.594 22.861 1.00 23.66 C ATOM 1957 N PHE C 637 11.406 40.974 29.106 1.00 27.46 N ATOM 1958 CA PHE C 637 11.570 40.322 30.410 1.00 28.17 C ATOM 1959 C PHE C 637 10.275 40.346 31.210 1.00 28.50 C ATOM 1960 O PHE C 637 9.473 41.255 31.096 1.00 28.56 O ATOM 1961 CB PHE C 637 12.669 41.035 31.236 1.00 27.46 C ATOM 1962 CG PHE C 637 14.016 41.107 30.526 1.00 28.36 C ATOM 1963 CD1 PHE C 637 14.301 42.160 29.646 1.00 26.65 C ATOM 1964 CD2 PHE C 637 14.990 40.116 30.740 1.00 27.68 C ATOM 1965 CE1 PHE C 637 15.526 42.229 28.966 1.00 27.06 C ATOM 1966 CE2 PHE C 637 16.227 40.171 30.084 1.00 26.04 C ATOM 1967 CZ PHE C 637 16.503 41.226 29.192 1.00 27.41 C ATOM 1968 N TRP C 638 10.090 39.323 32.015 1.00 29.68 N ATOM 1969 CA TRP C 638 9.049 39.279 33.006 1.00 30.45 C ATOM 1970 C TRP C 638 9.783 39.252 34.327 1.00 31.05 C ATOM 1971 O TRP C 638 10.635 38.397 34.544 1.00 30.90 O ATOM 1972 CB TRP C 638 8.205 38.027 32.854 1.00 30.73 C ATOM 1973 CG TRP C 638 7.049 37.993 33.826 1.00 31.92 C ATOM 1974 CD1 TRP C 638 7.055 37.493 35.103 1.00 31.56 C ATOM 1975 CD2 TRP C 638 5.723 38.487 33.591 1.00 32.48 C ATOM 1976 NE1 TRP C 638 5.813 37.638 35.672 1.00 32.19 N ATOM 1977 CE2 TRP C 638 4.968 38.230 34.762 1.00 33.10 C ATOM 1978 CE3 TRP C 638 5.097 39.107 32.500 1.00 32.53 C ATOM 1979 CZ2 TRP C 638 3.612 38.570 34.871 1.00 32.35 C ATOM 1980 CZ3 TRP C 638 3.745 39.452 32.603 1.00 32.55 C ATOM 1981 CH2 TRP C 638 3.017 39.183 33.786 1.00 32.80 C ATOM 1982 N CYS C 639 9.471 40.225 35.175 1.00 31.40 N ATOM 1983 CA CYS C 639 10.168 40.446 36.428 1.00 32.57 C ATOM 1984 C CYS C 639 9.198 40.273 37.582 1.00 33.90 C ATOM 1985 O CYS C 639 8.107 40.847 37.575 1.00 33.84 O ATOM 1986 CB CYS C 639 10.762 41.859 36.485 1.00 31.44 C ATOM 1987 SG CYS C 639 11.832 42.289 35.083 1.00 30.74 S ATOM 1988 N GLU C 640 9.622 39.481 38.568 1.00 35.37 N ATOM 1989 CA GLU C 640 8.914 39.327 39.825 1.00 36.01 C ATOM 1990 C GLU C 640 9.776 39.973 40.906 1.00 36.33 C ATOM 1991 O GLU C 640 10.992 39.787 40.898 1.00 37.38 O ATOM 1992 CB GLU C 640 8.703 37.848 40.120 1.00 36.55 C ATOM 1993 CG GLU C 640 7.788 37.140 39.137 1.00 37.22 C ATOM 1994 CD GLU C 640 6.306 37.469 39.336 1.00 39.17 C ATOM 1995 OE1 GLU C 640 5.940 38.153 40.328 1.00 38.36 O ATOM 1996 OE2 GLU C 640 5.492 37.013 38.500 1.00 39.79 O ATOM 1997 N PRO C 641 9.166 40.755 41.825 1.00 36.10 N ATOM 1998 CA PRO C 641 7.728 41.056 41.925 1.00 35.45 C ATOM 1999 C PRO C 641 7.235 42.082 40.895 1.00 34.94 C ATOM 2000 O PRO C 641 6.049 42.137 40.612 1.00 35.16 O ATOM 2001 CB PRO C 641 7.581 41.626 43.340 1.00 35.36 C ATOM 2002 CG PRO C 641 8.912 42.171 43.681 1.00 35.00 C ATOM 2003 CD PRO C 641 9.948 41.419 42.889 1.00 35.88 C ATOM 2004 N ASN C 642 8.149 42.879 40.352 1.00 34.49 N ATOM 2005 CA ASN C 642 7.843 43.817 39.277 1.00 33.99 C ATOM 2006 C ASN C 642 9.154 44.236 38.602 1.00 33.09 C ATOM 2007 O ASN C 642 10.247 43.841 39.057 1.00 32.82 O ATOM 2008 CB ASN C 642 7.059 45.043 39.800 1.00 33.30 C ATOM 2009 CG ASN C 642 7.839 45.849 40.838 1.00 34.91 C ATOM 2010 OD1 ASN C 642 8.971 46.269 40.603 1.00 32.61 O ATOM 2011 ND2 ASN C 642 7.228 46.062 42.009 1.00 37.22 N ATOM 2012 N ALA C 643 9.030 45.027 37.532 1.00 32.06 N ATOM 2013 CA ALA C 643 10.170 45.483 36.697 1.00 31.56 C ATOM 2014 C ALA C 643 10.938 46.715 37.216 1.00 31.11 C ATOM 2015 O ALA C 643 11.896 47.139 36.594 1.00 31.18 O ATOM 2016 CB ALA C 643 9.695 45.728 35.256 1.00 30.77 C ATOM 2017 N ALA C 644 10.538 47.292 38.353 1.00 31.12 N ATOM 2018 CA ALA C 644 11.175 48.516 38.828 1.00 30.73 C ATOM 2019 C ALA C 644 12.702 48.436 38.947 1.00 30.24 C ATOM 2020 O ALA C 644 13.431 49.240 38.345 1.00 29.79 O ATOM 2021 CB ALA C 644 10.551 48.983 40.167 1.00 32.03 C ATOM 2022 N SER C 645 13.201 47.462 39.696 1.00 29.26 N ATOM 2023 CA SER C 645 14.636 47.432 39.986 1.00 28.84 C ATOM 2024 C SER C 645 15.490 47.184 38.738 1.00 27.98 C ATOM 2025 O SER C 645 16.521 47.836 38.541 1.00 27.52 O ATOM 2026 CB SER C 645 14.957 46.432 41.115 1.00 29.51 C ATOM 2027 OG SER C 645 14.867 45.075 40.676 1.00 30.91 O ATOM 2028 N LEU C 646 15.042 46.283 37.875 1.00 27.75 N ATOM 2029 CA LEU C 646 15.774 46.003 36.644 1.00 28.03 C ATOM 2030 C LEU C 646 15.748 47.198 35.668 1.00 27.66 C ATOM 2031 O LEU C 646 16.778 47.600 35.144 1.00 27.48 O ATOM 2032 CB LEU C 646 15.254 44.721 35.982 1.00 27.65 C ATOM 2033 CG LEU C 646 15.965 44.423 34.643 1.00 29.12 C ATOM 2034 CD1 LEU C 646 17.535 44.383 34.816 1.00 27.94 C ATOM 2035 CD2 LEU C 646 15.412 43.131 33.973 1.00 29.13 C ATOM 2036 N SER C 647 14.572 47.798 35.470 1.00 28.32 N ATOM 2037 CA SER C 647 14.420 48.957 34.570 1.00 28.21 C ATOM 2038 C SER C 647 15.262 50.155 35.021 1.00 28.41 C ATOM 2039 O SER C 647 15.910 50.859 34.209 1.00 28.41 O ATOM 2040 CB SER C 647 12.929 49.316 34.436 1.00 28.64 C ATOM 2041 OG SER C 647 12.435 49.984 35.597 1.00 28.79 O ATOM 2042 N GLU C 648 15.289 50.373 36.328 1.00 29.20 N ATOM 2043 CA GLU C 648 16.113 51.433 36.927 1.00 29.75 C ATOM 2044 C GLU C 648 17.625 51.218 36.819 1.00 28.70 C ATOM 2045 O GLU C 648 18.358 52.153 36.529 1.00 27.95 O ATOM 2046 CB GLU C 648 15.677 51.668 38.376 1.00 31.13 C ATOM 2047 CG GLU C 648 14.315 52.386 38.413 1.00 37.38 C ATOM 2048 CD GLU C 648 13.822 52.675 39.818 1.00 46.87 C ATOM 2049 OE1 GLU C 648 14.497 53.448 40.558 1.00 50.85 O ATOM 2050 OE2 GLU C 648 12.739 52.134 40.176 1.00 49.35 O ATOM 2051 N ALA C 649 18.078 49.981 37.046 1.00 28.27 N ATOM 2052 CA ALA C 649 19.475 49.590 36.825 1.00 27.39 C ATOM 2053 C ALA C 649 19.896 49.825 35.382 1.00 26.63 C ATOM 2054 O ALA C 649 20.994 50.339 35.119 1.00 26.98 O ATOM 2055 CB ALA C 649 19.682 48.128 37.187 1.00 27.27 C ATOM 2056 N VAL C 650 19.045 49.437 34.439 1.00 26.39 N ATOM 2057 CA VAL C 650 19.382 49.648 33.026 1.00 26.06 C ATOM 2058 C VAL C 650 19.378 51.130 32.675 1.00 26.59 C ATOM 2059 O VAL C 650 20.259 51.613 31.952 1.00 25.99 O ATOM 2060 CB VAL C 650 18.493 48.836 32.042 1.00 26.05 C ATOM 2061 CG1 VAL C 650 18.837 49.224 30.605 1.00 26.02 C ATOM 2062 CG2 VAL C 650 18.693 47.337 32.245 1.00 25.83 C ATOM 2063 N GLN C 651 18.413 51.875 33.207 1.00 27.29 N ATOM 2064 CA GLN C 651 18.443 53.329 33.026 1.00 28.53 C ATOM 2065 C GLN C 651 19.745 53.893 33.601 1.00 27.45 C ATOM 2066 O GLN C 651 20.364 54.754 33.006 1.00 27.01 O ATOM 2067 CB GLN C 651 17.223 53.984 33.682 1.00 28.37 C ATOM 2068 CG GLN C 651 17.219 55.504 33.630 1.00 31.78 C ATOM 2069 CD GLN C 651 15.992 56.072 34.335 1.00 32.65 C ATOM 2070 OE1 GLN C 651 15.638 55.635 35.424 1.00 38.54 O ATOM 2071 NE2 GLN C 651 15.315 57.003 33.690 1.00 38.95 N ATOM 2072 N ALA C 652 20.148 53.397 34.762 1.00 28.22 N ATOM 2073 CA ALA C 652 21.392 53.830 35.409 1.00 28.72 C ATOM 2074 C ALA C 652 22.643 53.573 34.548 1.00 29.30 C ATOM 2075 O ALA C 652 23.505 54.453 34.396 1.00 29.53 O ATOM 2076 CB ALA C 652 21.520 53.157 36.790 1.00 28.60 C ATOM 2077 N ALA C 653 22.715 52.381 33.954 1.00 29.01 N ATOM 2078 CA ALA C 653 23.778 52.049 32.995 1.00 28.69 C ATOM 2079 C ALA C 653 23.852 53.054 31.867 1.00 28.48 C ATOM 2080 O ALA C 653 24.943 53.548 31.539 1.00 28.83 O ATOM 2081 CB ALA C 653 23.564 50.636 32.424 1.00 28.55 C ATOM 2082 N CYS C 654 22.699 53.367 31.266 1.00 28.25 N ATOM 2083 CA CYS C 654 22.613 54.405 30.230 1.00 27.70 C ATOM 2084 C CYS C 654 23.080 55.788 30.726 1.00 28.47 C ATOM 2085 O CYS C 654 23.751 56.517 29.993 1.00 28.93 O ATOM 2086 CB CYS C 654 21.178 54.560 29.739 1.00 27.38 C ATOM 2087 SG CYS C 654 20.475 53.176 28.939 1.00 27.01 S ATOM 2088 N MET C 655 22.724 56.159 31.952 1.00 28.35 N ATOM 2089 CA MET C 655 23.170 57.467 32.504 1.00 30.00 C ATOM 2090 C MET C 655 24.701 57.568 32.680 1.00 30.78 C ATOM 2091 O MET C 655 25.317 58.569 32.323 1.00 30.59 O ATOM 2092 CB MET C 655 22.480 57.749 33.849 1.00 29.44 C ATOM 2093 CG MET C 655 20.969 57.956 33.753 1.00 29.78 C ATOM 2094 SD MET C 655 20.047 57.623 35.278 1.00 30.59 S ATOM 2095 CE MET C 655 20.430 59.175 36.123 1.00 32.54 C ATOM 2096 N LEU C 656 25.300 56.518 33.240 1.00 32.25 N ATOM 2097 CA LEU C 656 26.751 56.469 33.426 1.00 33.78 C ATOM 2098 C LEU C 656 27.507 56.334 32.114 1.00 34.58 C ATOM 2099 O LEU C 656 28.567 56.937 31.938 1.00 35.22 O ATOM 2100 CB LEU C 656 27.097 55.322 34.365 1.00 33.37 C ATOM 2101 CG LEU C 656 26.607 55.549 35.785 1.00 33.14 C ATOM 2102 CD1 LEU C 656 26.551 54.241 36.489 1.00 31.34 C ATOM 2103 CD2 LEU C 656 27.496 56.565 36.551 1.00 32.80 C ATOM 2104 N ARG C 657 26.950 55.560 31.180 1.00 35.97 N ATOM 2105 CA ARG C 657 27.547 55.393 29.865 1.00 37.03 C ATOM 2106 C ARG C 657 27.545 56.707 29.077 1.00 37.92 C ATOM 2107 O ARG C 657 28.495 57.011 28.337 1.00 36.49 O ATOM 2108 CB ARG C 657 26.803 54.319 29.062 1.00 37.66 C ATOM 2109 CG ARG C 657 27.411 54.036 27.682 1.00 39.47 C ATOM 2110 CD ARG C 657 28.866 53.523 27.812 1.00 42.04 C ATOM 2111 NE ARG C 657 29.484 53.244 26.509 1.00 45.73 N ATOM 2112 CZ ARG C 657 30.059 54.153 25.704 1.00 47.11 C ATOM 2113 NH1 ARG C 657 30.110 55.449 26.029 1.00 46.58 N ATOM 2114 NH2 ARG C 657 30.582 53.761 24.544 1.00 46.53 N ATOM 2115 N TYR C 658 26.464 57.472 29.211 1.00 38.73 N ATOM 2116 CA TYR C 658 26.384 58.764 28.533 1.00 40.51 C ATOM 2117 C TYR C 658 27.460 59.741 29.046 1.00 41.45 C ATOM 2118 O TYR C 658 28.064 60.474 28.273 1.00 40.93 O ATOM 2119 CB TYR C 658 24.989 59.357 28.674 1.00 40.89 C ATOM 2120 CG TYR C 658 24.852 60.763 28.147 1.00 41.66 C ATOM 2121 CD1 TYR C 658 25.042 61.050 26.801 1.00 42.71 C ATOM 2122 CD2 TYR C 658 24.513 61.809 29.003 1.00 43.88 C ATOM 2123 CE1 TYR C 658 24.911 62.356 26.309 1.00 44.17 C ATOM 2124 CE2 TYR C 658 24.367 63.116 28.527 1.00 44.48 C ATOM 2125 CZ TYR C 658 24.570 63.380 27.183 1.00 44.18 C ATOM 2126 OH TYR C 658 24.413 64.670 26.719 1.00 44.59 O ATOM 2127 N GLN C 659 27.688 59.738 30.352 1.00 42.79 N ATOM 2128 CA GLN C 659 28.747 60.555 30.935 1.00 45.29 C ATOM 2129 C GLN C 659 30.152 60.212 30.386 1.00 46.58 C ATOM 2130 O GLN C 659 30.918 61.118 30.067 1.00 46.58 O ATOM 2131 CB GLN C 659 28.730 60.474 32.463 1.00 44.25 C ATOM 2132 CG GLN C 659 29.709 61.444 33.111 1.00 46.51 C ATOM 2133 CD GLN C 659 29.356 62.913 32.833 1.00 48.73 C ATOM 2134 OE1 GLN C 659 28.207 63.337 33.023 1.00 50.62 O ATOM 2135 NE2 GLN C 659 30.337 63.685 32.369 1.00 47.23 N ATOM 2136 N LYS C 660 30.483 58.922 30.290 1.00 48.79 N ATOM 2137 CA LYS C 660 31.744 58.485 29.662 1.00 51.30 C ATOM 2138 C LYS C 660 31.870 59.010 28.237 1.00 52.97 C ATOM 2139 O LYS C 660 32.928 59.477 27.815 1.00 53.30 O ATOM 2140 CB LYS C 660 31.848 56.967 29.620 1.00 51.42 C ATOM 2141 CG LYS C 660 31.929 56.271 30.951 1.00 52.75 C ATOM 2142 CD LYS C 660 32.563 54.891 30.734 1.00 58.01 C ATOM 2143 CE LYS C 660 31.895 53.800 31.577 1.00 60.37 C ATOM 2144 NZ LYS C 660 32.173 52.424 31.026 1.00 62.47 N ATOM 2145 N CYS C 661 30.777 58.919 27.495 1.00 55.25 N ATOM 2146 CA CYS C 661 30.701 59.477 26.168 1.00 56.88 C ATOM 2147 C CYS C 661 31.066 60.979 26.155 1.00 58.13 C ATOM 2148 O CYS C 661 31.831 61.421 25.295 1.00 58.55 O ATOM 2149 CB CYS C 661 29.317 59.211 25.587 1.00 56.71 C ATOM 2150 SG CYS C 661 29.014 60.085 24.096 1.00 58.59 S ATOM 2151 N LEU C 662 30.553 61.743 27.120 1.00 59.36 N ATOM 2152 CA LEU C 662 30.906 63.166 27.276 1.00 60.51 C ATOM 2153 C LEU C 662 32.343 63.368 27.759 1.00 61.75 C ATOM 2154 O LEU C 662 33.027 64.291 27.308 1.00 62.09 O ATOM 2155 CB LEU C 662 29.950 63.877 28.242 1.00 60.14 C ATOM 2156 CG LEU C 662 28.456 63.910 27.930 1.00 59.06 C ATOM 2157 CD1 LEU C 662 27.698 64.513 29.100 1.00 58.57 C ATOM 2158 CD2 LEU C 662 28.187 64.677 26.658 1.00 59.13 C ATOM 2159 N ASP C 663 32.794 62.514 28.677 1.00 63.13 N ATOM 2160 CA ASP C 663 34.146 62.614 29.235 1.00 64.81 C ATOM 2161 C ASP C 663 35.264 62.361 28.220 1.00 65.94 C ATOM 2162 O ASP C 663 36.336 62.966 28.308 1.00 66.09 O ATOM 2163 CB ASP C 663 34.305 61.709 30.458 1.00 64.78 C ATOM 2164 CG ASP C 663 33.907 62.408 31.749 1.00 65.70 C ATOM 2165 OD1 ASP C 663 32.702 62.587 31.995 1.00 65.82 O ATOM 2166 OD2 ASP C 663 34.803 62.802 32.520 1.00 68.47 O ATOM 2167 N ALA C 664 34.999 61.482 27.256 1.00 67.26 N ATOM 2168 CA ALA C 664 35.954 61.158 26.198 1.00 68.47 C ATOM 2169 C ALA C 664 36.005 62.208 25.078 1.00 69.40 C ATOM 2170 O ALA C 664 36.813 62.085 24.156 1.00 69.66 O ATOM 2171 CB ALA C 664 35.654 59.776 25.624 1.00 68.55 C ATOM 2172 N ARG C 665 35.154 63.233 25.162 1.00 70.36 N ATOM 2173 CA ARG C 665 35.100 64.298 24.148 1.00 71.39 C ATOM 2174 C ARG C 665 35.155 65.712 24.739 1.00 71.65 C ATOM 2175 O ARG C 665 35.806 65.953 25.765 1.00 72.04 O ATOM 2176 CB ARG C 665 33.856 64.135 23.267 1.00 71.61 C ATOM 2177 CG ARG C 665 34.011 63.033 22.232 1.00 73.17 C ATOM 2178 CD ARG C 665 32.677 62.458 21.769 1.00 75.68 C ATOM 2179 NE ARG C 665 32.900 61.359 20.828 1.00 77.90 N ATOM 2180 CZ ARG C 665 33.098 60.086 21.180 1.00 79.04 C ATOM 2181 NH1 ARG C 665 33.082 59.723 22.463 1.00 78.10 N ATOM 2182 NH2 ARG C 665 33.313 59.168 20.239 1.00 79.30 N TER 2183 ARG C 665 ATOM 2184 N VAL D 667 1.612 57.516 47.509 1.00 56.65 N ATOM 2185 CA VAL D 667 2.412 57.570 46.237 1.00 56.85 C ATOM 2186 C VAL D 667 3.900 57.266 46.502 1.00 55.91 C ATOM 2187 O VAL D 667 4.729 58.182 46.579 1.00 56.12 O ATOM 2188 CB VAL D 667 2.267 58.951 45.522 1.00 57.12 C ATOM 2189 CG1 VAL D 667 2.633 58.829 44.050 1.00 57.97 C ATOM 2190 CG2 VAL D 667 0.831 59.516 45.677 1.00 58.29 C ATOM 2191 N THR D 668 4.229 55.984 46.651 1.00 54.88 N ATOM 2192 CA THR D 668 5.604 55.576 46.996 1.00 53.98 C ATOM 2193 C THR D 668 6.625 55.968 45.916 1.00 52.98 C ATOM 2194 O THR D 668 6.245 56.172 44.754 1.00 52.65 O ATOM 2195 CB THR D 668 5.738 54.060 47.351 1.00 54.15 C ATOM 2196 OG1 THR D 668 5.815 53.266 46.156 1.00 54.43 O ATOM 2197 CG2 THR D 668 4.570 53.585 48.236 1.00 54.73 C ATOM 2198 N PRO D 669 7.914 56.127 46.312 1.00 51.91 N ATOM 2199 CA PRO D 669 8.975 56.426 45.345 1.00 51.06 C ATOM 2200 C PRO D 669 9.065 55.383 44.229 1.00 49.73 C ATOM 2201 O PRO D 669 9.201 55.758 43.068 1.00 48.57 O ATOM 2202 CB PRO D 669 10.249 56.426 46.210 1.00 51.07 C ATOM 2203 CG PRO D 669 9.766 56.802 47.548 1.00 51.35 C ATOM 2204 CD PRO D 669 8.451 56.092 47.686 1.00 51.87 C ATOM 2205 N GLU D 670 8.956 54.100 44.583 1.00 48.97 N ATOM 2206 CA GLU D 670 8.971 53.051 43.579 1.00 48.89 C ATOM 2207 C GLU D 670 7.818 53.231 42.582 1.00 48.57 C ATOM 2208 O GLU D 670 8.031 53.083 41.380 1.00 47.83 O ATOM 2209 CB GLU D 670 8.977 51.646 44.187 1.00 49.02 C ATOM 2210 CG GLU D 670 9.013 50.534 43.115 1.00 48.75 C ATOM 2211 CD GLU D 670 9.203 49.140 43.693 1.00 50.32 C ATOM 2212 OE1 GLU D 670 10.373 48.718 43.886 1.00 52.01 O ATOM 2213 OE2 GLU D 670 8.188 48.458 43.936 1.00 52.52 O ATOM 2214 N GLU D 671 6.620 53.565 43.087 1.00 47.93 N ATOM 2215 CA GLU D 671 5.423 53.831 42.245 1.00 46.98 C ATOM 2216 C GLU D 671 5.542 55.035 41.302 1.00 45.76 C ATOM 2217 O GLU D 671 5.137 54.963 40.148 1.00 45.08 O ATOM 2218 CB GLU D 671 4.174 53.989 43.124 1.00 47.02 C ATOM 2219 CG GLU D 671 3.712 52.683 43.750 1.00 48.10 C ATOM 2220 CD GLU D 671 2.744 52.866 44.929 1.00 48.74 C ATOM 2221 OE1 GLU D 671 2.344 54.023 45.248 1.00 48.83 O ATOM 2222 OE2 GLU D 671 2.393 51.822 45.527 1.00 50.45 O ATOM 2223 N ARG D 672 6.084 56.150 41.785 1.00 44.62 N ATOM 2224 CA ARG D 672 6.258 57.322 40.918 1.00 43.54 C ATOM 2225 C ARG D 672 7.233 57.057 39.740 1.00 42.11 C ATOM 2226 O ARG D 672 6.955 57.427 38.591 1.00 41.96 O ATOM 2227 CB ARG D 672 6.773 58.483 41.755 1.00 44.50 C ATOM 2228 CG ARG D 672 6.837 59.809 41.035 1.00 46.54 C ATOM 2229 CD ARG D 672 7.234 60.916 42.011 1.00 50.03 C ATOM 2230 NE ARG D 672 8.558 60.712 42.616 1.00 52.95 N ATOM 2231 CZ ARG D 672 8.772 60.341 43.883 1.00 54.10 C ATOM 2232 NH1 ARG D 672 7.757 60.107 44.716 1.00 54.10 N ATOM 2233 NH2 ARG D 672 10.019 60.207 44.320 1.00 54.67 N ATOM 2234 N AHIS D 673 8.372 56.430 40.020 0.50 41.25 N ATOM 2235 N BHIS D 673 8.370 56.443 40.075 0.50 41.24 N ATOM 2236 CA AHIS D 673 9.327 56.134 38.948 0.50 39.92 C ATOM 2237 CA BHIS D 673 9.388 56.031 39.107 0.50 39.95 C ATOM 2238 C AHIS D 673 8.850 54.980 38.056 0.50 38.79 C ATOM 2239 C BHIS D 673 8.797 55.038 38.106 0.50 38.75 C ATOM 2240 O AHIS D 673 9.129 54.990 36.859 0.50 38.58 O ATOM 2241 O BHIS D 673 8.921 55.232 36.895 0.50 38.48 O ATOM 2242 CB AHIS D 673 10.753 55.916 39.479 0.50 39.95 C ATOM 2243 CB BHIS D 673 10.626 55.454 39.826 0.50 39.84 C ATOM 2244 CG AHIS D 673 11.820 56.029 38.427 0.50 39.83 C ATOM 2245 CG BHIS D 673 11.529 56.509 40.391 0.50 40.24 C ATOM 2246 ND1AHIS D 673 13.116 55.614 38.641 0.50 40.09 N ATOM 2247 ND1BHIS D 673 12.497 57.140 39.636 0.50 38.97 N ATOM 2248 CD2AHIS D 673 11.780 56.489 37.151 0.50 38.66 C ATOM 2249 CD2BHIS D 673 11.587 57.072 41.624 0.50 38.99 C ATOM 2250 CE1AHIS D 673 13.828 55.814 37.546 0.50 37.43 C ATOM 2251 CE1BHIS D 673 13.113 58.044 40.381 0.50 39.41 C ATOM 2252 NE2AHIS D 673 13.043 56.348 36.630 0.50 37.49 N ATOM 2253 NE2BHIS D 673 12.579 58.023 41.590 0.50 39.09 N ATOM 2254 N LEU D 674 8.134 54.005 38.623 1.00 37.38 N ATOM 2255 CA LEU D 674 7.428 53.014 37.796 1.00 36.17 C ATOM 2256 C LEU D 674 6.445 53.644 36.815 1.00 34.58 C ATOM 2257 O LEU D 674 6.438 53.270 35.655 1.00 32.82 O ATOM 2258 CB LEU D 674 6.670 51.986 38.626 1.00 36.21 C ATOM 2259 CG LEU D 674 7.409 50.702 38.958 1.00 37.94 C ATOM 2260 CD1 LEU D 674 6.600 49.927 39.998 1.00 36.70 C ATOM 2261 CD2 LEU D 674 7.710 49.841 37.685 1.00 35.36 C ATOM 2262 N SER D 675 5.616 54.589 37.279 1.00 33.71 N ATOM 2263 CA SER D 675 4.646 55.275 36.402 1.00 33.76 C ATOM 2264 C SER D 675 5.279 55.974 35.209 1.00 32.59 C ATOM 2265 O SER D 675 4.829 55.822 34.084 1.00 31.93 O ATOM 2266 CB SER D 675 3.779 56.275 37.181 1.00 33.81 C ATOM 2267 OG SER D 675 2.710 55.592 37.786 1.00 38.78 O ATOM 2268 N LYS D 676 6.310 56.761 35.468 1.00 32.62 N ATOM 2269 CA LYS D 676 7.067 57.415 34.401 1.00 33.32 C ATOM 2270 C LYS D 676 7.666 56.396 33.426 1.00 32.31 C ATOM 2271 O LYS D 676 7.590 56.586 32.210 1.00 32.29 O ATOM 2272 CB LYS D 676 8.173 58.288 34.993 1.00 35.14 C ATOM 2273 CG LYS D 676 7.720 59.195 36.146 1.00 39.68 C ATOM 2274 CD LYS D 676 6.661 60.249 35.737 1.00 45.87 C ATOM 2275 CE LYS D 676 6.114 60.997 36.993 1.00 46.54 C ATOM 2276 NZ LYS D 676 7.217 61.641 37.838 1.00 50.63 N ATOM 2277 N MET D 677 8.231 55.306 33.956 1.00 30.72 N ATOM 2278 CA MET D 677 8.836 54.251 33.127 1.00 30.31 C ATOM 2279 C MET D 677 7.806 53.621 32.198 1.00 29.46 C ATOM 2280 O MET D 677 8.120 53.218 31.088 1.00 27.18 O ATOM 2281 CB MET D 677 9.483 53.177 34.011 1.00 30.68 C ATOM 2282 CG MET D 677 10.818 53.612 34.651 1.00 34.87 C ATOM 2283 SD MET D 677 12.196 53.820 33.469 1.00 42.75 S ATOM 2284 CE MET D 677 11.779 52.603 32.323 1.00 32.68 C ATOM 2285 N GLN D 678 6.557 53.551 32.670 1.00 29.09 N ATOM 2286 CA GLN D 678 5.461 52.997 31.888 1.00 29.44 C ATOM 2287 C GLN D 678 4.888 53.960 30.866 1.00 30.11 C ATOM 2288 O GLN D 678 4.553 53.561 29.742 1.00 29.56 O ATOM 2289 CB GLN D 678 4.328 52.556 32.816 1.00 29.32 C ATOM 2290 CG GLN D 678 4.612 51.286 33.572 1.00 29.22 C ATOM 2291 CD GLN D 678 3.438 50.914 34.443 1.00 29.64 C ATOM 2292 OE1 GLN D 678 3.012 51.708 35.267 1.00 30.97 O ATOM 2293 NE2 GLN D 678 2.876 49.732 34.224 1.00 29.32 N ATOM 2294 N GLN D 679 4.723 55.200 31.305 1.00 31.06 N ATOM 2295 CA GLN D 679 4.113 56.266 30.519 1.00 33.70 C ATOM 2296 C GLN D 679 5.034 56.835 29.455 1.00 32.60 C ATOM 2297 O GLN D 679 4.624 56.962 28.322 1.00 32.82 O ATOM 2298 CB GLN D 679 3.632 57.416 31.427 1.00 33.76 C ATOM 2299 CG GLN D 679 2.514 57.009 32.435 1.00 41.57 C ATOM 2300 CD GLN D 679 1.141 56.879 31.796 1.00 49.32 C ATOM 2301 OE1 GLN D 679 0.926 57.275 30.637 1.00 55.05 O ATOM 2302 NE2 GLN D 679 0.193 56.330 32.550 1.00 53.58 N ATOM 2303 N ASN D 680 6.258 57.181 29.837 1.00 32.58 N ATOM 2304 CA ASN D 680 7.235 57.812 28.928 1.00 33.32 C ATOM 2305 C ASN D 680 8.415 56.902 28.502 1.00 32.94 C ATOM 2306 O ASN D 680 9.043 57.106 27.456 1.00 32.57 O ATOM 2307 CB ASN D 680 7.775 59.081 29.581 1.00 33.59 C ATOM 2308 CG ASN D 680 6.644 60.109 29.916 1.00 37.62 C ATOM 2309 OD1 ASN D 680 6.495 60.536 31.067 1.00 42.73 O ATOM 2310 ND2 ASN D 680 5.854 60.472 28.918 1.00 39.39 N ATOM 2311 N GLY D 681 8.711 55.911 29.328 1.00 32.14 N ATOM 2312 CA GLY D 681 9.885 55.085 29.117 1.00 31.21 C ATOM 2313 C GLY D 681 11.105 55.971 29.290 1.00 30.78 C ATOM 2314 O GLY D 681 11.061 56.990 29.994 1.00 30.12 O ATOM 2315 N TYR D 682 12.196 55.590 28.642 1.00 29.42 N ATOM 2316 CA TYR D 682 13.442 56.347 28.753 1.00 28.90 C ATOM 2317 C TYR D 682 14.262 56.184 27.479 1.00 28.84 C ATOM 2318 O TYR D 682 14.559 55.068 27.077 1.00 27.61 O ATOM 2319 CB TYR D 682 14.229 55.872 29.972 1.00 29.00 C ATOM 2320 CG TYR D 682 15.587 56.502 30.157 1.00 29.71 C ATOM 2321 CD1 TYR D 682 15.731 57.709 30.821 1.00 28.38 C ATOM 2322 CD2 TYR D 682 16.745 55.854 29.693 1.00 29.08 C ATOM 2323 CE1 TYR D 682 17.001 58.272 31.016 1.00 31.00 C ATOM 2324 CE2 TYR D 682 17.995 56.407 29.862 1.00 27.88 C ATOM 2325 CZ TYR D 682 18.124 57.601 30.525 1.00 30.60 C ATOM 2326 OH TYR D 682 19.383 58.132 30.696 1.00 34.16 O ATOM 2327 N GLU D 683 14.596 57.315 26.862 1.00 28.75 N ATOM 2328 CA GLU D 683 15.427 57.380 25.668 1.00 30.75 C ATOM 2329 C GLU D 683 16.870 57.525 26.110 1.00 29.71 C ATOM 2330 O GLU D 683 17.211 58.424 26.872 1.00 28.86 O ATOM 2331 CB GLU D 683 15.034 58.582 24.788 1.00 30.64 C ATOM 2332 CG GLU D 683 13.603 58.468 24.245 1.00 33.78 C ATOM 2333 CD GLU D 683 13.250 59.559 23.219 1.00 34.78 C ATOM 2334 OE1 GLU D 683 14.102 60.417 22.912 1.00 42.09 O ATOM 2335 OE2 GLU D 683 12.116 59.539 22.711 1.00 41.63 O ATOM 2336 N ASN D 684 17.713 56.603 25.655 1.00 30.09 N ATOM 2337 CA ASN D 684 19.101 56.577 26.089 1.00 29.91 C ATOM 2338 C ASN D 684 19.811 57.776 25.452 1.00 30.63 C ATOM 2339 O ASN D 684 19.868 57.866 24.231 1.00 30.19 O ATOM 2340 CB ASN D 684 19.733 55.241 25.683 1.00 29.65 C ATOM 2341 CG ASN D 684 21.205 55.147 26.047 1.00 29.81 C ATOM 2342 OD1 ASN D 684 21.744 55.984 26.784 1.00 29.86 O ATOM 2343 ND2 ASN D 684 21.864 54.125 25.537 1.00 29.24 N ATOM 2344 N PRO D 685 20.340 58.703 26.282 1.00 31.73 N ATOM 2345 CA PRO D 685 21.023 59.881 25.759 1.00 33.35 C ATOM 2346 C PRO D 685 22.361 59.554 25.076 1.00 34.85 C ATOM 2347 O PRO D 685 22.843 60.370 24.311 1.00 34.33 O ATOM 2348 CB PRO D 685 21.261 60.735 27.015 1.00 32.76 C ATOM 2349 CG PRO D 685 21.343 59.765 28.102 1.00 32.16 C ATOM 2350 CD PRO D 685 20.383 58.672 27.756 1.00 31.70 C ATOM 2351 N THR D 686 22.950 58.387 25.373 1.00 37.30 N ATOM 2352 CA THR D 686 24.204 57.952 24.727 1.00 39.26 C ATOM 2353 C THR D 686 23.940 57.755 23.244 1.00 40.96 C ATOM 2354 O THR D 686 24.677 58.284 22.404 1.00 41.78 O ATOM 2355 CB THR D 686 24.750 56.631 25.286 1.00 38.95 C ATOM 2356 OG1 THR D 686 24.676 56.620 26.716 1.00 39.33 O ATOM 2357 CG2 THR D 686 26.204 56.410 24.849 1.00 39.37 C ATOM 2358 N TYR D 687 22.883 57.000 22.933 1.00 42.27 N ATOM 2359 CA TYR D 687 22.484 56.709 21.569 1.00 44.14 C ATOM 2360 C TYR D 687 22.087 57.972 20.825 1.00 46.77 C ATOM 2361 O TYR D 687 22.402 58.124 19.646 1.00 46.69 O ATOM 2362 CB TYR D 687 21.352 55.676 21.545 1.00 43.52 C ATOM 2363 CG TYR D 687 20.791 55.377 20.167 1.00 43.03 C ATOM 2364 CD1 TYR D 687 21.439 54.497 19.298 1.00 43.36 C ATOM 2365 CD2 TYR D 687 19.610 55.978 19.731 1.00 42.74 C ATOM 2366 CE1 TYR D 687 20.913 54.228 18.014 1.00 42.80 C ATOM 2367 CE2 TYR D 687 19.076 55.713 18.468 1.00 43.04 C ATOM 2368 CZ TYR D 687 19.737 54.833 17.616 1.00 43.71 C ATOM 2369 OH TYR D 687 19.208 54.557 16.370 1.00 44.87 O ATOM 2370 N LYS D 688 21.386 58.868 21.517 1.00 49.80 N ATOM 2371 CA LYS D 688 21.000 60.166 20.963 1.00 53.31 C ATOM 2372 C LYS D 688 22.242 61.020 20.670 1.00 55.20 C ATOM 2373 O LYS D 688 22.299 61.689 19.644 1.00 55.91 O ATOM 2374 CB LYS D 688 20.060 60.892 21.925 1.00 53.07 C ATOM 2375 CG LYS D 688 19.218 61.996 21.293 1.00 54.70 C ATOM 2376 CD LYS D 688 18.313 62.676 22.324 1.00 54.37 C ATOM 2377 CE LYS D 688 17.238 61.709 22.858 1.00 56.30 C ATOM 2378 NZ LYS D 688 16.477 62.255 24.035 1.00 55.56 N ATOM 2379 N PHE D 689 23.228 60.976 21.566 1.00 57.69 N ATOM 2380 CA PHE D 689 24.503 61.679 21.382 1.00 60.25 C ATOM 2381 C PHE D 689 25.244 61.169 20.149 1.00 61.73 C ATOM 2382 O PHE D 689 25.543 61.931 19.216 1.00 62.07 O ATOM 2383 CB PHE D 689 25.413 61.498 22.608 1.00 60.36 C ATOM 2384 CG PHE D 689 26.729 62.233 22.503 1.00 61.75 C ATOM 2385 CD1 PHE D 689 27.741 61.779 21.650 1.00 62.82 C ATOM 2386 CD2 PHE D 689 26.955 63.387 23.247 1.00 62.64 C ATOM 2387 CE1 PHE D 689 28.956 62.461 21.551 1.00 63.32 C ATOM 2388 CE2 PHE D 689 28.167 64.075 23.151 1.00 63.25 C ATOM 2389 CZ PHE D 689 29.168 63.609 22.307 1.00 62.73 C ATOM 2390 N PHE D 690 25.545 59.873 20.177 1.00 63.12 N ATOM 2391 CA PHE D 690 26.309 59.204 19.135 1.00 64.59 C ATOM 2392 C PHE D 690 25.563 59.139 17.820 1.00 65.59 C ATOM 2393 O PHE D 690 26.058 58.569 16.861 1.00 66.01 O ATOM 2394 CB PHE D 690 26.680 57.796 19.581 1.00 64.30 C ATOM 2395 CG PHE D 690 27.965 57.714 20.350 1.00 64.64 C ATOM 2396 CD1 PHE D 690 29.162 58.144 19.785 1.00 64.62 C ATOM 2397 CD2 PHE D 690 27.987 57.175 21.628 1.00 64.46 C ATOM 2398 CE1 PHE D 690 30.349 58.047 20.490 1.00 64.71 C ATOM 2399 CE2 PHE D 690 29.176 57.070 22.338 1.00 64.82 C ATOM 2400 CZ PHE D 690 30.359 57.509 21.770 1.00 64.46 C ATOM 2401 N GLU D 691 24.371 59.724 17.785 1.00 67.25 N ATOM 2402 CA GLU D 691 23.631 59.897 16.547 1.00 68.82 C ATOM 2403 C GLU D 691 24.143 61.128 15.787 1.00 69.84 C ATOM 2404 O GLU D 691 23.746 61.364 14.636 1.00 70.16 O ATOM 2405 CB GLU D 691 22.129 60.005 16.832 1.00 68.89 C ATOM 2406 CG GLU D 691 21.221 59.445 15.732 1.00 69.80 C ATOM 2407 CD GLU D 691 21.429 57.953 15.490 1.00 70.31 C ATOM 2408 OE1 GLU D 691 22.064 57.282 16.335 1.00 70.59 O ATOM 2409 OE2 GLU D 691 20.959 57.453 14.446 1.00 70.03 O ATOM 2410 N GLN D 692 25.013 61.907 16.445 1.00 70.96 N ATOM 2411 CA GLN D 692 25.720 63.047 15.824 1.00 71.73 C ATOM 2412 C GLN D 692 27.229 63.035 16.126 1.00 71.68 C ATOM 2413 O GLN D 692 27.993 62.231 15.577 1.00 71.56 O ATOM 2414 CB GLN D 692 25.120 64.382 16.281 1.00 72.10 C ATOM 2415 CG GLN D 692 23.727 64.682 15.734 1.00 73.96 C ATOM 2416 CD GLN D 692 22.624 64.007 16.533 1.00 75.94 C ATOM 2417 OE1 GLN D 692 22.574 64.114 17.763 1.00 76.90 O ATOM 2418 NE2 GLN D 692 21.728 63.311 15.834 1.00 76.76 N TER 2419 GLN D 692 HETATM 2420 O HOH A 1 -24.571 45.555 29.694 1.00 17.80 O HETATM 2421 O HOH A 4 0.495 51.151 25.146 1.00 25.24 O HETATM 2422 O HOH A 5 -29.810 50.017 25.670 1.00 26.51 O HETATM 2423 O HOH A 7 -6.772 49.305 34.953 1.00 20.89 O HETATM 2424 O HOH A 8 -19.487 43.577 31.179 1.00 23.82 O HETATM 2425 O HOH A 9 -20.720 49.694 40.498 1.00 23.24 O HETATM 2426 O HOH A 12 -11.410 41.133 13.113 1.00 27.35 O HETATM 2427 O HOH A 13 1.259 43.713 15.271 1.00 29.72 O HETATM 2428 O HOH A 15 -26.192 50.192 16.991 1.00 34.59 O HETATM 2429 O HOH A 16 0.870 33.501 26.883 1.00 35.22 O HETATM 2430 O HOH A 17 -13.295 56.444 12.265 1.00 28.25 O HETATM 2431 O HOH A 23 -10.706 57.839 32.574 1.00 38.63 O HETATM 2432 O HOH A 26 -23.779 45.297 33.988 1.00 27.22 O HETATM 2433 O HOH A 33 -17.142 56.917 26.388 1.00 38.40 O HETATM 2434 O HOH A 35 -2.272 42.867 9.467 1.00 39.18 O HETATM 2435 O HOH A 36 0.528 51.202 17.883 1.00 33.70 O HETATM 2436 O HOH A 37 -34.266 46.520 27.257 1.00 37.54 O HETATM 2437 O HOH A 38 -23.382 41.097 30.427 1.00 36.58 O HETATM 2438 O HOH A 45 -9.859 42.033 9.929 1.00 34.89 O HETATM 2439 O HOH A 51 -25.879 41.008 20.133 1.00 37.66 O HETATM 2440 O HOH A 53 -10.351 35.385 14.217 1.00 51.63 O HETATM 2441 O HOH A 59 -14.772 49.330 7.208 1.00 49.42 O HETATM 2442 O HOH A 64 -7.970 56.673 31.160 1.00 42.61 O HETATM 2443 O HOH A 72 -27.607 49.889 24.058 1.00 31.84 O HETATM 2444 O HOH A 74 -14.105 40.670 35.268 1.00 42.33 O HETATM 2445 O HOH A 75 1.736 39.066 16.840 1.00 48.90 O HETATM 2446 O HOH A 77 -5.461 56.926 25.737 1.00 43.04 O HETATM 2447 O HOH A 80 -23.112 59.139 15.701 1.00 30.70 O HETATM 2448 O HOH A 82 -2.674 50.009 32.532 1.00 49.57 O HETATM 2449 O HOH A 84 -15.445 42.627 36.176 1.00 48.88 O HETATM 2450 O HOH A 86 -16.960 35.702 32.450 1.00 48.94 O HETATM 2451 O HOH A 92 -12.652 35.549 31.755 1.00 35.79 O HETATM 2452 O HOH A 93 0.918 35.960 16.071 1.00 47.70 O HETATM 2453 O HOH A 95 -18.188 37.242 29.241 1.00 51.58 O HETATM 2454 O HOH A 100 -9.081 35.438 31.188 1.00 48.84 O HETATM 2455 O HOH A 105 -30.677 50.718 18.735 1.00 46.70 O HETATM 2456 O HOH A 108 -5.011 45.419 33.896 1.00 48.83 O HETATM 2457 O HOH A 114 -16.180 58.137 28.499 1.00 49.43 O HETATM 2458 O HOH A 116 -13.681 48.909 38.029 1.00 35.33 O HETATM 2459 O HOH A 118 -8.194 32.022 27.619 1.00 62.23 O HETATM 2460 O HOH A 120 3.559 47.804 17.894 1.00 45.20 O HETATM 2461 O HOH A 123 -34.232 57.050 16.774 1.00 56.68 O HETATM 2462 O HOH A 129 2.010 32.928 29.015 1.00 55.76 O HETATM 2463 O HOH A 130 1.530 49.217 16.798 1.00 61.00 O HETATM 2464 O HOH A 132 -23.007 43.768 30.618 1.00 63.62 O HETATM 2465 O HOH A 136 -5.556 47.791 32.751 1.00 39.10 O HETATM 2466 O HOH A 137 -5.536 56.622 30.019 1.00 64.21 O HETATM 2467 O HOH A 138 -10.223 33.162 13.009 1.00 56.60 O HETATM 2468 O HOH A 139 -27.311 37.155 27.224 1.00 42.87 O HETATM 2469 O HOH A 140 -14.272 37.015 34.462 1.00 54.61 O HETATM 2470 O HOH A 143 -18.086 39.766 33.695 1.00 57.64 O HETATM 2471 O HOH A 145 -25.677 41.285 30.169 1.00 39.24 O HETATM 2472 O HOH A 146 -1.958 45.361 33.735 1.00 50.89 O HETATM 2473 O HOH A 148 -28.539 51.347 16.744 1.00 48.11 O HETATM 2474 O HOH A 153 -25.935 37.278 29.300 1.00 53.26 O HETATM 2475 O HOH A 156 -18.832 42.224 34.758 1.00 53.87 O HETATM 2476 O HOH A 157 1.768 29.853 19.896 1.00 44.44 O HETATM 2477 O HOH A 158 -1.882 55.534 27.256 1.00 53.98 O HETATM 2478 O HOH A 162 -15.017 34.646 30.643 1.00 58.43 O HETATM 2479 O HOH A 166 -11.738 37.674 35.252 1.00 50.78 O HETATM 2480 O HOH A 167 -0.979 34.489 14.999 1.00 51.70 O HETATM 2481 O HOH A 169 -30.459 44.833 19.238 1.00 48.58 O HETATM 2482 O HOH A 171 -1.043 56.382 24.821 1.00 49.95 O HETATM 2483 O HOH A 173 -5.718 52.095 35.087 1.00 61.89 O HETATM 2484 O HOH A 175 -27.295 38.978 18.253 1.00 51.27 O HETATM 2485 O HOH A 176 -1.861 36.570 11.639 1.00 56.74 O HETATM 2486 O HOH A 178 -10.569 35.600 9.212 1.00 70.21 O HETATM 2487 O HOH A 181 -33.394 51.980 17.741 1.00 57.28 O HETATM 2488 O HOH A 184 -15.764 34.616 36.397 1.00 50.83 O HETATM 2489 O HOH A 188 -29.784 58.133 13.203 1.00 64.53 O HETATM 2490 O HOH A 189 -28.654 55.462 13.556 1.00 52.46 O HETATM 2491 O HOH A 193 -24.728 54.903 29.734 1.00 51.58 O HETATM 2492 O HOH A 195 -10.942 32.387 26.925 1.00 53.40 O HETATM 2493 O HOH A 196 -21.432 25.009 24.165 1.00 77.75 O HETATM 2494 O HOH A 201 -7.086 34.073 28.075 1.00 58.60 O HETATM 2495 O HOH A 202 -17.518 44.784 40.467 1.00 47.41 O HETATM 2496 O HOH A 207 -11.998 33.994 10.897 1.00 50.16 O HETATM 2497 O HOH A 208 2.374 45.735 16.566 1.00 59.34 O HETATM 2498 O HOH A 211 -26.365 29.727 25.473 1.00 56.64 O HETATM 2499 O HOH A 214 -5.349 38.524 33.738 1.00 41.69 O HETATM 2500 O HOH A 221 -2.834 37.814 35.046 1.00 62.61 O HETATM 2501 O HOH A 226 -15.177 44.985 37.225 1.00 58.77 O HETATM 2502 O HOH A 231 2.292 31.328 18.223 1.00 62.24 O HETATM 2503 O HOH A 233 -3.824 30.999 17.413 1.00 65.55 O HETATM 2504 O HOH A 234 -4.038 56.064 36.592 1.00 66.22 O HETATM 2505 O HOH B 32 -3.421 50.217 21.452 1.00 27.19 O HETATM 2506 O HOH B 56 -1.377 56.099 21.695 1.00 44.41 O HETATM 2507 O HOH B 63 -20.391 54.491 34.811 1.00 42.96 O HETATM 2508 O HOH B 65 -2.061 50.437 10.218 1.00 43.74 O HETATM 2509 O HOH B 71 -9.621 59.919 7.774 1.00 39.25 O HETATM 2510 O HOH B 76 0.753 47.323 14.955 1.00 39.38 O HETATM 2511 O HOH B 83 -1.217 54.888 9.327 1.00 48.67 O HETATM 2512 O HOH B 87 -17.364 57.330 33.489 1.00 43.97 O HETATM 2513 O HOH B 91 -16.681 60.719 22.145 1.00 55.04 O HETATM 2514 O HOH B 103 -15.800 57.228 35.406 1.00 44.43 O HETATM 2515 O HOH B 111 -9.256 57.611 25.873 1.00 41.92 O HETATM 2516 O HOH B 112 -10.943 53.128 6.968 1.00 49.12 O HETATM 2517 O HOH B 124 -7.653 58.493 27.773 1.00 46.90 O HETATM 2518 O HOH B 128 -0.837 49.893 12.634 1.00 51.97 O HETATM 2519 O HOH B 135 -15.870 59.450 20.011 1.00 37.71 O HETATM 2520 O HOH B 150 -12.754 52.328 4.810 1.00 38.36 O HETATM 2521 O HOH B 170 -9.887 42.876 7.565 1.00 47.92 O HETATM 2522 O HOH B 194 -8.229 47.954 2.846 1.00 46.36 O HETATM 2523 O HOH B 197 -4.242 46.827 4.538 1.00 57.48 O HETATM 2524 O HOH B 216 -8.819 58.655 16.068 1.00 52.33 O HETATM 2525 O HOH B 219 -11.447 55.599 8.324 1.00 63.80 O HETATM 2526 O HOH B 220 -17.690 59.402 31.251 1.00 69.91 O HETATM 2527 O HOH B 224 -21.299 62.438 23.586 1.00 46.62 O HETATM 2528 O HOH B 229 -7.285 56.614 24.012 1.00 59.92 O HETATM 2529 O HOH C 2 30.266 50.399 23.010 1.00 20.80 O HETATM 2530 O HOH C 3 0.202 45.856 36.311 1.00 21.67 O HETATM 2531 O HOH C 6 7.280 47.932 15.769 1.00 28.82 O HETATM 2532 O HOH C 10 0.469 52.804 32.287 1.00 28.79 O HETATM 2533 O HOH C 14 20.311 48.426 9.394 1.00 26.99 O HETATM 2534 O HOH C 18 6.324 46.845 18.353 1.00 30.95 O HETATM 2535 O HOH C 19 25.313 45.272 21.051 1.00 26.92 O HETATM 2536 O HOH C 20 12.907 44.293 38.662 1.00 31.22 O HETATM 2537 O HOH C 21 31.523 49.331 31.947 1.00 39.54 O HETATM 2538 O HOH C 22 6.398 56.918 23.839 1.00 33.47 O HETATM 2539 O HOH C 24 20.002 43.360 19.647 1.00 28.80 O HETATM 2540 O HOH C 27 18.699 33.739 38.073 1.00 32.76 O HETATM 2541 O HOH C 28 9.936 45.410 12.283 1.00 38.52 O HETATM 2542 O HOH C 29 11.372 45.743 41.419 1.00 33.29 O HETATM 2543 O HOH C 34 14.983 39.687 16.730 1.00 42.77 O HETATM 2544 O HOH C 39 29.079 44.161 19.778 1.00 37.21 O HETATM 2545 O HOH C 40 34.977 46.657 21.931 1.00 37.61 O HETATM 2546 O HOH C 41 26.557 62.059 34.660 1.00 38.45 O HETATM 2547 O HOH C 43 26.311 41.046 20.840 1.00 40.91 O HETATM 2548 O HOH C 44 18.521 40.460 36.928 1.00 41.09 O HETATM 2549 O HOH C 47 21.953 27.135 29.923 1.00 47.58 O HETATM 2550 O HOH C 48 27.370 43.195 31.328 1.00 37.83 O HETATM 2551 O HOH C 49 32.279 56.893 24.146 1.00 42.99 O HETATM 2552 O HOH C 50 24.275 47.080 17.784 1.00 36.62 O HETATM 2553 O HOH C 52 4.199 45.719 42.230 1.00 38.56 O HETATM 2554 O HOH C 54 0.728 30.460 30.456 1.00 40.60 O HETATM 2555 O HOH C 57 15.563 50.741 41.817 1.00 36.95 O HETATM 2556 O HOH C 58 28.428 50.607 25.395 1.00 33.09 O HETATM 2557 O HOH C 60 0.740 38.288 37.195 1.00 39.89 O HETATM 2558 O HOH C 61 24.122 43.707 37.755 1.00 43.87 O HETATM 2559 O HOH C 62 28.069 31.075 26.996 1.00 36.94 O HETATM 2560 O HOH C 66 3.945 39.313 41.144 1.00 41.86 O HETATM 2561 O HOH C 67 3.112 43.696 17.736 1.00 36.14 O HETATM 2562 O HOH C 68 32.384 63.401 34.507 1.00 52.25 O HETATM 2563 O HOH C 69 -0.499 50.296 33.408 1.00 38.88 O HETATM 2564 O HOH C 70 14.863 53.181 10.305 1.00 49.83 O HETATM 2565 O HOH C 78 17.686 27.170 35.560 1.00 50.11 O HETATM 2566 O HOH C 79 24.073 44.685 16.398 1.00 33.18 O HETATM 2567 O HOH C 81 6.051 50.271 15.197 1.00 45.86 O HETATM 2568 O HOH C 89 14.051 47.231 12.579 1.00 42.16 O HETATM 2569 O HOH C 94 26.801 54.945 15.388 1.00 52.44 O HETATM 2570 O HOH C 96 20.748 38.756 21.018 1.00 53.33 O HETATM 2571 O HOH C 97 6.003 44.400 17.586 1.00 42.45 O HETATM 2572 O HOH C 98 28.788 37.353 24.865 1.00 76.74 O HETATM 2573 O HOH C 99 32.820 56.055 17.884 1.00 50.09 O HETATM 2574 O HOH C 101 16.751 37.032 38.343 1.00 33.62 O HETATM 2575 O HOH C 102 17.146 32.803 24.968 1.00 42.19 O HETATM 2576 O HOH C 104 15.475 27.243 30.681 1.00 51.19 O HETATM 2577 O HOH C 106 10.448 34.431 22.497 1.00 46.70 O HETATM 2578 O HOH C 107 27.173 55.401 17.778 1.00 52.77 O HETATM 2579 O HOH C 109 19.461 37.721 23.039 1.00 54.68 O HETATM 2580 O HOH C 110 22.314 32.305 39.052 1.00 41.39 O HETATM 2581 O HOH C 113 13.768 35.212 21.018 1.00 43.34 O HETATM 2582 O HOH C 117 15.872 41.905 15.302 1.00 50.32 O HETATM 2583 O HOH C 119 6.575 41.778 17.200 1.00 54.91 O HETATM 2584 O HOH C 121 18.168 28.854 27.013 1.00 47.29 O HETATM 2585 O HOH C 122 -0.083 40.459 35.766 1.00 41.08 O HETATM 2586 O HOH C 125 11.251 52.533 37.974 1.00 59.25 O HETATM 2587 O HOH C 126 16.900 35.690 41.003 1.00 64.05 O HETATM 2588 O HOH C 131 12.901 53.718 43.388 1.00 51.13 O HETATM 2589 O HOH C 133 23.945 38.775 21.696 1.00 48.62 O HETATM 2590 O HOH C 141 0.387 48.914 35.919 1.00 46.92 O HETATM 2591 O HOH C 144 12.557 32.699 26.923 1.00 50.54 O HETATM 2592 O HOH C 149 10.443 31.788 20.745 1.00 54.45 O HETATM 2593 O HOH C 151 22.512 43.918 20.526 1.00 46.56 O HETATM 2594 O HOH C 152 26.838 41.329 37.517 1.00 54.07 O HETATM 2595 O HOH C 155 3.059 36.860 38.346 1.00 51.53 O HETATM 2596 O HOH C 160 10.798 36.021 20.213 1.00 54.72 O HETATM 2597 O HOH C 161 34.497 48.514 23.547 1.00 50.12 O HETATM 2598 O HOH C 164 4.403 58.132 25.630 1.00 51.31 O HETATM 2599 O HOH C 168 6.670 46.282 13.849 1.00 52.16 O HETATM 2600 O HOH C 172 16.797 34.961 22.367 1.00 58.21 O HETATM 2601 O HOH C 174 21.008 28.568 27.832 1.00 57.18 O HETATM 2602 O HOH C 179 25.937 64.613 32.117 1.00 53.00 O HETATM 2603 O HOH C 182 27.914 35.029 36.128 1.00 59.03 O HETATM 2604 O HOH C 183 30.626 33.415 28.338 1.00 49.83 O HETATM 2605 O HOH C 185 8.716 33.382 39.590 1.00 51.99 O HETATM 2606 O HOH C 186 12.873 49.996 10.530 1.00 48.64 O HETATM 2607 O HOH C 192 5.830 51.315 12.291 1.00 50.60 O HETATM 2608 O HOH C 198 31.898 52.284 27.966 1.00 47.58 O HETATM 2609 O HOH C 199 9.571 32.614 26.191 1.00 62.09 O HETATM 2610 O HOH C 200 6.535 37.193 19.005 1.00 51.04 O HETATM 2611 O HOH C 203 6.110 55.035 17.669 1.00 58.14 O HETATM 2612 O HOH C 205 25.366 54.935 19.234 1.00 51.93 O HETATM 2613 O HOH C 209 26.139 46.543 19.156 1.00 52.32 O HETATM 2614 O HOH C 210 20.173 36.023 40.056 1.00 55.89 O HETATM 2615 O HOH C 212 19.652 25.140 31.501 1.00 60.01 O HETATM 2616 O HOH C 213 3.962 50.792 17.502 1.00 53.63 O HETATM 2617 O HOH C 217 12.926 41.394 39.105 1.00 64.56 O HETATM 2618 O HOH C 223 24.093 41.060 20.845 1.00 44.12 O HETATM 2619 O HOH C 228 24.277 61.041 33.065 1.00 49.51 O HETATM 2620 O HOH C 230 29.035 33.706 31.278 1.00 56.59 O HETATM 2621 O HOH C 232 14.202 33.314 25.084 1.00 51.61 O HETATM 2622 O HOH C 235 3.409 42.273 41.491 1.00 61.48 O HETATM 2623 O HOH D 11 13.448 59.963 27.899 1.00 29.07 O HETATM 2624 O HOH D 25 4.296 51.119 29.075 1.00 28.49 O HETATM 2625 O HOH D 30 17.983 57.130 22.520 1.00 37.95 O HETATM 2626 O HOH D 31 12.600 58.695 45.335 1.00 34.99 O HETATM 2627 O HOH D 42 9.773 52.844 47.460 1.00 45.41 O HETATM 2628 O HOH D 46 16.718 60.815 28.040 1.00 35.11 O HETATM 2629 O HOH D 55 11.365 56.846 16.003 1.00 37.92 O HETATM 2630 O HOH D 73 2.165 56.654 27.527 1.00 45.30 O HETATM 2631 O HOH D 85 22.170 62.960 24.227 1.00 49.97 O HETATM 2632 O HOH D 88 3.333 50.777 40.912 1.00 65.31 O HETATM 2633 O HOH D 90 13.436 58.621 17.611 1.00 61.49 O HETATM 2634 O HOH D 115 16.034 57.670 18.344 1.00 56.32 O HETATM 2635 O HOH D 127 1.998 51.760 37.865 1.00 45.15 O HETATM 2636 O HOH D 134 11.911 59.572 30.231 1.00 57.27 O HETATM 2637 O HOH D 142 22.359 64.703 22.162 1.00 55.51 O HETATM 2638 O HOH D 147 14.549 55.493 12.670 1.00 50.86 O HETATM 2639 O HOH D 154 9.285 61.806 28.342 1.00 62.38 O HETATM 2640 O HOH D 159 24.300 54.877 16.784 1.00 49.85 O HETATM 2641 O HOH D 163 5.843 49.305 43.690 1.00 47.66 O HETATM 2642 O HOH D 165 -0.717 56.186 29.483 1.00 56.24 O HETATM 2643 O HOH D 177 9.820 58.016 22.872 1.00 54.71 O HETATM 2644 O HOH D 180 10.623 59.284 26.499 1.00 54.44 O HETATM 2645 O HOH D 187 16.968 58.720 20.825 1.00 57.21 O HETATM 2646 O HOH D 190 12.140 47.169 43.713 1.00 52.41 O HETATM 2647 O HOH D 191 17.848 61.855 26.064 1.00 62.01 O HETATM 2648 O HOH D 204 19.456 60.221 31.612 1.00 45.00 O HETATM 2649 O HOH D 206 10.141 60.249 39.123 1.00 45.58 O HETATM 2650 O HOH D 215 1.352 54.088 34.331 1.00 54.45 O HETATM 2651 O HOH D 218 29.448 62.339 18.257 1.00 69.13 O HETATM 2652 O HOH D 222 -1.513 57.237 48.526 1.00 60.26 O HETATM 2653 O HOH D 225 11.312 57.739 33.261 1.00 51.77 O HETATM 2654 O HOH D 227 12.810 50.737 43.587 1.00 58.75 O HETATM 2655 O HOH D 236 20.523 53.406 14.500 1.00 51.43 O MASTER 371 0 0 10 16 0 0 6 2631 4 0 28 END
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Related entries of code: 3dxc
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
1x11
RCSB PDB
PDBbind
13aa, >1X11_2|Chains... at 100%
2roz
RCSB PDB
PDBbind
32aa, >2ROZ_1|Chain... at 100%
3dxd
RCSB PDB
PDBbind
35aa, >3DXD_2|Chains... at 97%
3dxe
RCSB PDB
PDBbind
35aa, >3DXE_2|Chains... at 97%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
3dxc
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
Fe65-PTB2
Ligand Name
APP intracellular domain
EC.Number
E.C.-.-.-.-
Resolution
2.1(Å)
Affinity (Kd/Ki/IC50)
Kd=0.22uM
Release Year
2008
Protein/NA Sequence
Check fasta file
Primary Reference
(2008) Embo Rep. Vol. 9: pp. 1134-1140
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
O00213
P05067
Entrez Gene ID
NCBI Entrez Gene ID:
322
351
ASD
Information of known allosteric effects of PDB entries
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