Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 12-FEB-09 3G8U TITLE DNA BINDING DOMAIN:GILZ 16BP COMPLEX-5 COMPND MOL_ID: 1; COMPND 2 MOLECULE: GLUCOCORTICOID RECEPTOR; COMPND 3 CHAIN: A, B; COMPND 4 FRAGMENT: UNP RESIDUES 440-525; COMPND 5 SYNONYM: GR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 1; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)- COMPND 9 3'); COMPND 10 CHAIN: D; COMPND 11 ENGINEERED: YES; COMPND 12 OTHER_DETAILS: GLUCOCORTICOID RECEPTOR BINDING SITE GILZ BOTTOM COMPND 13 STRAND; COMPND 14 MOL_ID: 3; COMPND 15 MOLECULE: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)- COMPND 16 3'); COMPND 17 CHAIN: C; COMPND 18 ENGINEERED: YES; COMPND 19 OTHER_DETAILS: GLUCOCORTICOID RECEPTOR BINDING SITE GILZ TOP STRAND SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: RATTUS NORVEGICUS; SOURCE 3 ORGANISM_COMMON: BROWN RAT,RAT,RATS; SOURCE 4 ORGANISM_TAXID: 10116; SOURCE 5 GENE: GRL, NR3C1; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) GOLD; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET28A; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 MOL_ID: 3; SOURCE 14 SYNTHETIC: YES KEYWDS GLUCOCORTICOID, DNA-BINDING, ALLOSTERY, LEVER ARM, TRANSCRIPTION, KEYWDS 2 HORMONE, ALTERNATIVE INITIATION, CHROMATIN REGULATOR, CYTOPLASM, KEYWDS 3 LIPID-BINDING, METAL-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, KEYWDS 4 RECEPTOR, STEROID-BINDING, TRANSCRIPTION REGULATION, UBL KEYWDS 5 CONJUGATION, ZINC, ZINC-FINGER, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR M.A.PUFALL,K.R.YAMAMOTO,S.H.MEIJSING REVDAT 3 01-NOV-17 3G8U 1 REMARK REVDAT 2 02-JUN-09 3G8U 1 JRNL REVDAT 1 21-APR-09 3G8U 0 JRNL AUTH S.H.MEIJSING,M.A.PUFALL,A.Y.SO,D.L.BATES,L.CHEN,K.R.YAMAMOTO JRNL TITL DNA BINDING SITE SEQUENCE DIRECTS GLUCOCORTICOID RECEPTOR JRNL TITL 2 STRUCTURE AND ACTIVITY. JRNL REF SCIENCE V. 324 407 2009 JRNL REFN ISSN 0036-8075 JRNL PMID 19372434 JRNL DOI 10.1126/SCIENCE.1164265 REMARK 2 REMARK 2 RESOLUTION. 1.90 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (PHENIX.REFINE) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.90 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 29.20 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 0.080 REMARK 3 COMPLETENESS FOR RANGE (%) : 86.8 REMARK 3 NUMBER OF REFLECTIONS : 25403 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.212 REMARK 3 R VALUE (WORKING SET) : 0.210 REMARK 3 FREE R VALUE : 0.236 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 7.380 REMARK 3 FREE R VALUE TEST SET COUNT : 1874 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 29.2027 - 4.0938 0.99 2798 228 0.1975 0.2268 REMARK 3 2 4.0938 - 3.2508 0.99 2695 221 0.1935 0.2038 REMARK 3 3 3.2508 - 2.8403 0.99 2707 211 0.2260 0.2653 REMARK 3 4 2.8403 - 2.5807 0.98 2637 206 0.2084 0.2382 REMARK 3 5 2.5807 - 2.3959 0.96 2613 210 0.2155 0.2334 REMARK 3 6 2.3959 - 2.2547 0.94 2535 203 0.2049 0.2263 REMARK 3 7 2.2547 - 2.1418 0.90 2430 191 0.2326 0.2741 REMARK 3 8 2.1418 - 2.0486 0.85 2267 174 0.2435 0.2444 REMARK 3 9 2.0486 - 1.9697 0.65 1733 151 0.2673 0.3367 REMARK 3 10 1.9697 - 1.9000 0.41 1114 79 0.2960 0.3183 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : 0.39 REMARK 3 B_SOL : 82.46 REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 1.300 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : NULL REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 38.60 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 82.98 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.013 NULL REMARK 3 ANGLE : 1.462 NULL REMARK 3 CHIRALITY : NULL NULL REMARK 3 PLANARITY : NULL NULL REMARK 3 DIHEDRAL : NULL NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 4 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN A REMARK 3 ORIGIN FOR THE GROUP (A): 19.6338 -13.7244 -0.9354 REMARK 3 T TENSOR REMARK 3 T11: 0.1956 T22: 0.2157 REMARK 3 T33: 0.5278 T12: 0.0513 REMARK 3 T13: 0.0044 T23: -0.1084 REMARK 3 L TENSOR REMARK 3 L11: 5.6675 L22: 1.1550 REMARK 3 L33: 2.3677 L12: -1.5847 REMARK 3 L13: 1.3303 L23: -1.2397 REMARK 3 S TENSOR REMARK 3 S11: 0.3281 S12: 0.1859 S13: -1.3562 REMARK 3 S21: -0.0081 S22: -0.1922 S23: 0.5705 REMARK 3 S31: -0.0414 S32: -0.2550 S33: -0.1032 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN B REMARK 3 ORIGIN FOR THE GROUP (A): 35.3555 -19.1384 20.7698 REMARK 3 T TENSOR REMARK 3 T11: 0.6319 T22: 0.5117 REMARK 3 T33: 0.3661 T12: -0.1689 REMARK 3 T13: -0.0952 T23: 0.1316 REMARK 3 L TENSOR REMARK 3 L11: 2.8597 L22: 2.1498 REMARK 3 L33: 1.0906 L12: -1.4126 REMARK 3 L13: -0.3567 L23: -2.5133 REMARK 3 S TENSOR REMARK 3 S11: -0.2355 S12: -0.8087 S13: -0.1526 REMARK 3 S21: 0.8381 S22: -0.2177 S23: -0.3691 REMARK 3 S31: -0.8896 S32: 0.4795 S33: 0.3354 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN C REMARK 3 ORIGIN FOR THE GROUP (A): 14.3411 -13.1466 18.1510 REMARK 3 T TENSOR REMARK 3 T11: 0.7697 T22: 0.9178 REMARK 3 T33: 0.4780 T12: 0.3793 REMARK 3 T13: -0.0907 T23: -0.1037 REMARK 3 L TENSOR REMARK 3 L11: 3.8981 L22: 1.6773 REMARK 3 L33: 5.2838 L12: -1.9531 REMARK 3 L13: 1.5322 L23: -4.4848 REMARK 3 S TENSOR REMARK 3 S11: -0.6227 S12: -1.0359 S13: -0.7131 REMARK 3 S21: 0.8724 S22: 1.1242 S23: 0.3797 REMARK 3 S31: -1.7037 S32: -1.3475 S33: -0.3896 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN D REMARK 3 ORIGIN FOR THE GROUP (A): 16.1462 -16.0270 21.7271 REMARK 3 T TENSOR REMARK 3 T11: 0.4668 T22: 1.0535 REMARK 3 T33: 0.5080 T12: 0.0994 REMARK 3 T13: -0.0601 T23: 0.2640 REMARK 3 L TENSOR REMARK 3 L11: -0.9527 L22: 3.0650 REMARK 3 L33: 2.1346 L12: -2.2023 REMARK 3 L13: 0.4159 L23: -1.5622 REMARK 3 S TENSOR REMARK 3 S11: -0.4999 S12: -1.0233 S13: -0.5336 REMARK 3 S21: 0.5605 S22: 0.5713 S23: 0.6152 REMARK 3 S31: -0.7423 S32: -0.6084 S33: -0.0718 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 3G8U COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 17-FEB-09. REMARK 100 THE DEPOSITION ID IS D_1000051568. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 16-SEP-06 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 5.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ALS REMARK 200 BEAMLINE : 8.3.1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.115878 REMARK 200 MONOCHROMATOR : DOUBLE FLAT CRYSTAL, SI(111) REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 210 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 27207 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.900 REMARK 200 RESOLUTION RANGE LOW (A) : 30.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 0.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 93.4 REMARK 200 DATA REDUNDANCY : 6.400 REMARK 200 R MERGE (I) : 0.07500 REMARK 200 R SYM (I) : 0.06800 REMARK 200
FOR THE DATA SET : 13.4000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.90 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.97 REMARK 200 COMPLETENESS FOR SHELL (%) : 56.7 REMARK 200 DATA REDUNDANCY IN SHELL : 2.80 REMARK 200 R MERGE FOR SHELL (I) : 0.62000 REMARK 200 R SYM FOR SHELL (I) : 0.62400 REMARK 200
FOR SHELL : 1.400 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX REMARK 200 STARTING MODEL: 1GLU REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 60.57 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.12 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 50MM MES, PH 5.6, 200MM KCL, 10MM REMARK 280 MGCL2, 5% PEG 8000, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE REMARK 280 298K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,Y+1/2,Z REMARK 290 4555 -X+1/2,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 58.47050 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 19.30250 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 58.47050 REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 19.30250 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5100 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 12390 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -25.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, D, C REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 436 REMARK 465 ILE A 516 REMARK 465 LYS A 517 REMARK 465 GLY A 518 REMARK 465 ILE A 519 REMARK 465 GLN A 520 REMARK 465 GLN A 521 REMARK 465 ALA A 522 REMARK 465 THR A 523 REMARK 465 ALA A 524 REMARK 465 GLY A 525 REMARK 465 GLY B 436 REMARK 465 SER B 437 REMARK 465 HIS B 438 REMARK 465 LYS B 511 REMARK 465 THR B 512 REMARK 465 LYS B 513 REMARK 465 LYS B 514 REMARK 465 LYS B 515 REMARK 465 ILE B 516 REMARK 465 LYS B 517 REMARK 465 GLY B 518 REMARK 465 ILE B 519 REMARK 465 GLN B 520 REMARK 465 GLN B 521 REMARK 465 ALA B 522 REMARK 465 THR B 523 REMARK 465 ALA B 524 REMARK 465 GLY B 525 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 LYS A 513 CG CD CE NZ REMARK 470 LYS A 514 CG CD CE NZ REMARK 470 LYS A 515 CG CD CE NZ REMARK 470 ARG B 510 CG CD NE CZ NH1 NH2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O HOH D 18 O HOH D 51 2.03 REMARK 500 O HOH A 40 O HOH D 41 2.17 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 CYS A 495 CB CYS A 495 SG 0.108 REMARK 500 DT D 11 C5' DT D 11 C4' 0.046 REMARK 500 DT D 11 C1' DT D 11 N1 0.082 REMARK 500 DG D 12 P DG D 12 O5' 0.070 REMARK 500 DG D 12 C5' DG D 12 C4' 0.082 REMARK 500 DT D 13 O3' DT D 13 C3' -0.039 REMARK 500 DT D 14 O3' DT D 14 C3' -0.036 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 ARG A 496 NE - CZ - NH1 ANGL. DEV. = -3.1 DEGREES REMARK 500 DT D 1 O4' - C1' - N1 ANGL. DEV. = 3.4 DEGREES REMARK 500 DC D 6 O4' - C1' - N1 ANGL. DEV. = 1.9 DEGREES REMARK 500 DC D 7 O4' - C1' - N1 ANGL. DEV. = 2.7 DEGREES REMARK 500 DT D 11 C5' - C4' - C3' ANGL. DEV. = 7.8 DEGREES REMARK 500 DT D 11 N3 - C4 - O4 ANGL. DEV. = 3.8 DEGREES REMARK 500 DG D 12 O4' - C4' - C3' ANGL. DEV. = -3.0 DEGREES REMARK 500 DG D 12 C3' - C2' - C1' ANGL. DEV. = -5.9 DEGREES REMARK 500 DG D 12 O4' - C1' - N9 ANGL. DEV. = 4.7 DEGREES REMARK 500 DT D 13 O4' - C1' - N1 ANGL. DEV. = 3.9 DEGREES REMARK 500 DT D 14 O4' - C1' - N1 ANGL. DEV. = -8.6 DEGREES REMARK 500 DT D 14 N3 - C4 - O4 ANGL. DEV. = 3.9 DEGREES REMARK 500 DT D 16 O5' - C5' - C4' ANGL. DEV. = -8.6 DEGREES REMARK 500 DT D 16 O4' - C4' - C3' ANGL. DEV. = -3.3 DEGREES REMARK 500 DT D 16 C5' - C4' - C3' ANGL. DEV. = 7.5 DEGREES REMARK 500 DT D 16 C1' - O4' - C4' ANGL. DEV. = -7.4 DEGREES REMARK 500 DT D 16 C4' - C3' - C2' ANGL. DEV. = -4.3 DEGREES REMARK 500 DT D 16 O4' - C1' - N1 ANGL. DEV. = 4.6 DEGREES REMARK 500 DA C 1 C1' - O4' - C4' ANGL. DEV. = -7.8 DEGREES REMARK 500 DA C 1 O4' - C1' - C2' ANGL. DEV. = 4.3 DEGREES REMARK 500 DA C 1 O4' - C1' - N9 ANGL. DEV. = 3.4 DEGREES REMARK 500 DA C 1 C2 - N3 - C4 ANGL. DEV. = -5.2 DEGREES REMARK 500 DA C 1 C5 - C6 - N1 ANGL. DEV. = -4.6 DEGREES REMARK 500 DA C 2 O5' - P - OP2 ANGL. DEV. = -6.4 DEGREES REMARK 500 DA C 2 O5' - C5' - C4' ANGL. DEV. = -5.0 DEGREES REMARK 500 DG C 3 C3' - C2' - C1' ANGL. DEV. = -7.9 DEGREES REMARK 500 DG C 3 O4' - C1' - N9 ANGL. DEV. = 5.8 DEGREES REMARK 500 DA C 5 C3' - C2' - C1' ANGL. DEV. = -6.8 DEGREES REMARK 500 DA C 5 O4' - C1' - N9 ANGL. DEV. = 5.8 DEGREES REMARK 500 DT C 8 O4' - C1' - N1 ANGL. DEV. = 3.6 DEGREES REMARK 500 DT C 9 C3' - O3' - P ANGL. DEV. = 9.8 DEGREES REMARK 500 DG C 11 O4' - C1' - C2' ANGL. DEV. = 3.4 DEGREES REMARK 500 DG C 12 O3' - P - OP1 ANGL. DEV. = 8.5 DEGREES REMARK 500 DG C 12 O4' - C1' - N9 ANGL. DEV. = 3.2 DEGREES REMARK 500 DC C 16 C3' - C2' - C1' ANGL. DEV. = -5.2 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 HIS A 438 -2.06 -146.19 REMARK 500 ASN A 473 49.26 -96.17 REMARK 500 ASN A 480 34.67 34.54 REMARK 500 ASP A 481 33.76 -143.91 REMARK 500 ASP A 485 -163.94 -113.64 REMARK 500 VAL B 442 -66.99 -96.50 REMARK 500 SER B 444 24.46 45.09 REMARK 500 ASP B 445 -148.60 -64.05 REMARK 500 GLN B 471 -23.07 74.20 REMARK 500 HIS B 472 152.80 -38.94 REMARK 500 ASP B 481 48.98 -151.75 REMARK 500 ASN B 506 136.78 -170.75 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 526 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 440 SG REMARK 620 2 CYS A 443 SG 111.7 REMARK 620 3 CYS A 457 SG 114.6 108.8 REMARK 620 4 CYS A 460 SG 105.8 110.2 105.6 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 527 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 476 SG REMARK 620 2 CYS A 482 SG 101.8 REMARK 620 3 CYS A 492 SG 113.1 116.4 REMARK 620 4 CYS A 495 SG 105.1 111.0 108.7 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN B 526 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS B 440 SG REMARK 620 2 CYS B 443 SG 129.4 REMARK 620 3 CYS B 457 SG 114.9 98.8 REMARK 620 4 CYS B 460 SG 108.0 111.8 84.9 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN B 527 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS B 476 SG REMARK 620 2 CYS B 482 SG 106.0 REMARK 620 3 CYS B 492 SG 113.8 112.3 REMARK 620 4 CYS B 495 SG 107.2 109.9 107.5 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 526 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 527 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN B 526 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN B 527 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 3FYL RELATED DB: PDB REMARK 900 SAME PROTEIN, DIFFERENT DNA REMARK 900 RELATED ID: 3G6P RELATED DB: PDB REMARK 900 SAME COMPLEX, DIFFERENT CRYSTAL CONDITION REMARK 900 RELATED ID: 3G6Q RELATED DB: PDB REMARK 900 SAME DNA BINDING SITE, INSERTION MUTATION GR GAMMA REMARK 900 RELATED ID: 3G6R RELATED DB: PDB REMARK 900 RELATED ID: 3G6U RELATED DB: PDB REMARK 900 RELATED ID: 3G8X RELATED DB: PDB REMARK 900 RELATED ID: 3G97 RELATED DB: PDB REMARK 900 RELATED ID: 3G99 RELATED DB: PDB REMARK 900 RELATED ID: 3G9I RELATED DB: PDB REMARK 900 RELATED ID: 3G9J RELATED DB: PDB REMARK 900 RELATED ID: 3G9M RELATED DB: PDB REMARK 900 RELATED ID: 3G9O RELATED DB: PDB REMARK 900 RELATED ID: 3G9P RELATED DB: PDB DBREF 3G8U A 440 525 UNP P06536 GCR_RAT 440 525 DBREF 3G8U B 440 525 UNP P06536 GCR_RAT 440 525 DBREF 3G8U C 1 16 PDB 3G8U 3G8U 1 16 DBREF 3G8U D 1 16 PDB 3G8U 3G8U 1 16 SEQADV 3G8U GLY A 436 UNP P06536 EXPRESSION TAG SEQADV 3G8U SER A 437 UNP P06536 EXPRESSION TAG SEQADV 3G8U HIS A 438 UNP P06536 EXPRESSION TAG SEQADV 3G8U MET A 439 UNP P06536 EXPRESSION TAG SEQADV 3G8U GLY B 436 UNP P06536 EXPRESSION TAG SEQADV 3G8U SER B 437 UNP P06536 EXPRESSION TAG SEQADV 3G8U HIS B 438 UNP P06536 EXPRESSION TAG SEQADV 3G8U MET B 439 UNP P06536 EXPRESSION TAG SEQRES 1 A 90 GLY SER HIS MET CYS LEU VAL CYS SER ASP GLU ALA SER SEQRES 2 A 90 GLY CYS HIS TYR GLY VAL LEU THR CYS GLY SER CYS LYS SEQRES 3 A 90 VAL PHE PHE LYS ARG ALA VAL GLU GLY GLN HIS ASN TYR SEQRES 4 A 90 LEU CYS ALA GLY ARG ASN ASP CYS ILE ILE ASP LYS ILE SEQRES 5 A 90 ARG ARG LYS ASN CYS PRO ALA CYS ARG TYR ARG LYS CYS SEQRES 6 A 90 LEU GLN ALA GLY MET ASN LEU GLU ALA ARG LYS THR LYS SEQRES 7 A 90 LYS LYS ILE LYS GLY ILE GLN GLN ALA THR ALA GLY SEQRES 1 B 90 GLY SER HIS MET CYS LEU VAL CYS SER ASP GLU ALA SER SEQRES 2 B 90 GLY CYS HIS TYR GLY VAL LEU THR CYS GLY SER CYS LYS SEQRES 3 B 90 VAL PHE PHE LYS ARG ALA VAL GLU GLY GLN HIS ASN TYR SEQRES 4 B 90 LEU CYS ALA GLY ARG ASN ASP CYS ILE ILE ASP LYS ILE SEQRES 5 B 90 ARG ARG LYS ASN CYS PRO ALA CYS ARG TYR ARG LYS CYS SEQRES 6 B 90 LEU GLN ALA GLY MET ASN LEU GLU ALA ARG LYS THR LYS SEQRES 7 B 90 LYS LYS ILE LYS GLY ILE GLN GLN ALA THR ALA GLY SEQRES 1 D 16 DT DG DG DA DA DC DC DC DA DA DT DG DT SEQRES 2 D 16 DT DC DT SEQRES 1 C 16 DA DA DG DA DA DC DA DT DT DG DG DG DT SEQRES 2 C 16 DT DC DC HET ZN A 526 1 HET ZN A 527 1 HET ZN B 526 1 HET ZN B 527 1 HETNAM ZN ZINC ION FORMUL 5 ZN 4(ZN 2+) FORMUL 9 HOH *84(H2 O) HELIX 1 1 CYS A 457 GLY A 470 1 14 HELIX 2 2 ILE A 487 ASN A 491 5 5 HELIX 3 3 CYS A 492 GLY A 504 1 13 HELIX 4 4 GLU A 508 LYS A 514 1 7 HELIX 5 5 CYS B 457 GLN B 471 1 15 HELIX 6 6 ARG B 488 ASN B 491 5 4 HELIX 7 7 CYS B 492 ALA B 503 1 12 SHEET 1 A 2 CYS A 450 HIS A 451 0 SHEET 2 A 2 VAL A 454 LEU A 455 -1 O VAL A 454 N HIS A 451 SHEET 1 B 2 GLY B 449 HIS B 451 0 SHEET 2 B 2 VAL B 454 THR B 456 -1 O VAL B 454 N HIS B 451 LINK SG CYS A 440 ZN ZN A 526 1555 1555 2.41 LINK SG CYS A 443 ZN ZN A 526 1555 1555 2.24 LINK SG CYS A 457 ZN ZN A 526 1555 1555 2.33 LINK SG CYS A 460 ZN ZN A 526 1555 1555 2.33 LINK SG CYS A 476 ZN ZN A 527 1555 1555 2.40 LINK SG CYS A 482 ZN ZN A 527 1555 1555 2.21 LINK SG CYS A 492 ZN ZN A 527 1555 1555 2.29 LINK SG CYS A 495 ZN ZN A 527 1555 1555 2.34 LINK SG CYS B 440 ZN ZN B 526 1555 1555 2.19 LINK SG CYS B 443 ZN ZN B 526 1555 1555 2.39 LINK SG CYS B 457 ZN ZN B 526 1555 1555 2.52 LINK SG CYS B 460 ZN ZN B 526 1555 1555 2.46 LINK SG CYS B 476 ZN ZN B 527 1555 1555 2.23 LINK SG CYS B 482 ZN ZN B 527 1555 1555 2.24 LINK SG CYS B 492 ZN ZN B 527 1555 1555 2.35 LINK SG CYS B 495 ZN ZN B 527 1555 1555 2.39 SITE 1 AC1 4 CYS A 440 CYS A 443 CYS A 457 CYS A 460 SITE 1 AC2 4 CYS A 476 CYS A 482 CYS A 492 CYS A 495 SITE 1 AC3 4 CYS B 440 CYS B 443 CYS B 457 CYS B 460 SITE 1 AC4 4 CYS B 476 CYS B 482 CYS B 492 CYS B 495 CRYST1 116.941 38.605 98.518 90.00 123.51 90.00 C 1 2 1 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.008551 0.000000 0.005662 0.00000 SCALE2 0.000000 0.025903 0.000000 0.00000 SCALE3 0.000000 0.000000 0.012174 0.00000 ATOM 1 N SER A 437 13.063 -24.715 -12.671 1.00170.19 N ANISOU 1 N SER A 437 17564 18972 28128 1512 -3680 -6426 N ATOM 2 CA SER A 437 13.745 -25.661 -11.799 1.00170.48 C ANISOU 2 CA SER A 437 17576 18495 28702 1357 -3707 -6232 C ATOM 3 C SER A 437 12.953 -25.834 -10.513 1.00169.58 C ANISOU 3 C SER A 437 17330 18026 29077 980 -3584 -5625 C ATOM 4 O SER A 437 11.732 -25.716 -10.515 1.00168.97 O ANISOU 4 O SER A 437 17076 17942 29184 845 -3653 -5547 O ATOM 5 CB SER A 437 15.158 -25.173 -11.487 1.00166.84 C ANISOU 5 CB SER A 437 17396 18251 27743 1473 -3414 -6027 C ATOM 6 OG SER A 437 15.859 -24.861 -12.677 1.00166.74 O ANISOU 6 OG SER A 437 17489 18672 27192 1835 -3481 -6509 O ATOM 7 N HIS A 438 13.643 -26.117 -9.414 1.00172.59 N ANISOU 7 N HIS A 438 17776 18149 29653 820 -3401 -5175 N ATOM 8 CA HIS A 438 12.964 -26.256 -8.132 1.00162.24 C ANISOU 8 CA HIS A 438 16322 16575 28745 488 -3253 -4542 C ATOM 9 C HIS A 438 13.788 -25.777 -6.927 1.00114.01 C ANISOU 9 C HIS A 438 10417 10548 22355 388 -2863 -3952 C ATOM 10 O HIS A 438 13.296 -25.784 -5.795 1.00 79.23 O ANISOU 10 O HIS A 438 5906 6021 18176 147 -2694 -3387 O ATOM 11 CB HIS A 438 12.530 -27.707 -7.925 1.00186.08 C ANISOU 11 CB HIS A 438 19006 18961 32736 304 -3608 -4596 C ATOM 12 CG HIS A 438 11.581 -27.884 -6.786 1.00197.41 C ANISOU 12 CG HIS A 438 20207 20177 34622 -28 -3505 -3958 C ATOM 13 ND1 HIS A 438 10.526 -27.026 -6.562 1.00199.03 N ANISOU 13 ND1 HIS A 438 20373 20703 34545 -114 -3322 -3672 N ATOM 14 CD2 HIS A 438 11.523 -28.816 -5.806 1.00203.82 C ANISOU 14 CD2 HIS A 438 20788 20514 36138 -278 -3553 -3521 C ATOM 15 CE1 HIS A 438 9.860 -27.420 -5.492 1.00203.30 C ANISOU 15 CE1 HIS A 438 20666 21007 35572 -393 -3256 -3092 C ATOM 16 NE2 HIS A 438 10.444 -28.504 -5.014 1.00207.12 N ANISOU 16 NE2 HIS A 438 21022 21011 36664 -505 -3393 -2972 N ATOM 17 N MET A 439 15.018 -25.337 -7.165 1.00 93.63 N ANISOU 17 N MET A 439 8107 8208 19261 580 -2722 -4071 N ATOM 18 CA MET A 439 15.897 -24.949 -6.056 1.00 97.59 C ANISOU 18 CA MET A 439 8793 8770 19515 490 -2394 -3559 C ATOM 19 C MET A 439 16.177 -23.462 -6.040 1.00 78.66 C ANISOU 19 C MET A 439 6693 6901 16293 586 -2071 -3404 C ATOM 20 O MET A 439 16.285 -22.834 -7.099 1.00 72.05 O ANISOU 20 O MET A 439 5975 6401 15001 804 -2107 -3774 O ATOM 21 CB MET A 439 17.229 -25.698 -6.134 1.00 98.65 C ANISOU 21 CB MET A 439 8988 8706 19790 597 -2481 -3723 C ATOM 22 CG MET A 439 17.059 -27.208 -6.284 1.00119.86 C ANISOU 22 CG MET A 439 11391 10822 23329 545 -2848 -3959 C ATOM 23 SD MET A 439 16.455 -28.032 -4.795 1.00158.85 S ANISOU 23 SD MET A 439 16052 15267 29038 171 -2814 -3283 S ATOM 24 CE MET A 439 17.961 -28.807 -4.213 1.00114.47 C ANISOU 24 CE MET A 439 10493 9374 23626 201 -2781 -3133 C ATOM 25 N CYS A 440 16.306 -22.910 -4.834 1.00 66.46 N ANISOU 25 N CYS A 440 5255 5431 14568 431 -1768 -2852 N ATOM 26 CA CYS A 440 16.604 -21.501 -4.644 1.00 64.27 C ANISOU 26 CA CYS A 440 5262 5586 13572 496 -1472 -2666 C ATOM 27 C CYS A 440 17.935 -21.121 -5.301 1.00 64.00 C ANISOU 27 C CYS A 440 5459 5773 13086 696 -1443 -2905 C ATOM 28 O CYS A 440 18.930 -21.793 -5.117 1.00 62.57 O ANISOU 28 O CYS A 440 5286 5422 13067 707 -1485 -2914 O ATOM 29 CB CYS A 440 16.648 -21.189 -3.142 1.00 55.54 C ANISOU 29 CB CYS A 440 4207 4470 12424 307 -1197 -2070 C ATOM 30 SG CYS A 440 17.210 -19.504 -2.739 1.00 55.97 S ANISOU 30 SG CYS A 440 4633 4977 11654 377 -861 -1844 S ATOM 31 N LEU A 441 17.961 -20.036 -6.058 1.00 54.74 N ANISOU 31 N LEU A 441 4455 4994 11350 858 -1367 -3064 N ATOM 32 CA LEU A 441 19.145 -19.668 -6.816 1.00 58.49 C ANISOU 32 CA LEU A 441 5098 5728 11399 1062 -1356 -3278 C ATOM 33 C LEU A 441 20.172 -18.971 -5.942 1.00 66.34 C ANISOU 33 C LEU A 441 6324 6835 12048 988 -1096 -2885 C ATOM 34 O LEU A 441 21.235 -18.614 -6.423 1.00 64.11 O ANISOU 34 O LEU A 441 6173 6772 11412 1125 -1062 -2968 O ATOM 35 CB LEU A 441 18.772 -18.684 -7.925 1.00 62.36 C ANISOU 35 CB LEU A 441 5657 6629 11408 1256 -1359 -3515 C ATOM 36 CG LEU A 441 18.591 -19.351 -9.289 1.00 81.89 C ANISOU 36 CG LEU A 441 7960 9166 13989 1480 -1653 -4080 C ATOM 37 CD1 LEU A 441 18.351 -20.841 -9.162 1.00 86.91 C ANISOU 37 CD1 LEU A 441 8365 9343 15313 1411 -1912 -4293 C ATOM 38 CD2 LEU A 441 17.417 -18.688 -9.976 1.00 80.33 C ANISOU 38 CD2 LEU A 441 7702 9213 13606 1550 -1690 -4215 C ATOM 39 N VAL A 442 19.812 -18.728 -4.689 1.00 61.91 N ANISOU 39 N VAL A 442 5795 6162 11564 782 -921 -2457 N ATOM 40 CA VAL A 442 20.709 -18.085 -3.741 1.00 55.16 C ANISOU 40 CA VAL A 442 5149 5403 10406 698 -694 -2090 C ATOM 41 C VAL A 442 21.330 -19.144 -2.866 1.00 66.86 C ANISOU 41 C VAL A 442 6534 6590 12281 574 -708 -1891 C ATOM 42 O VAL A 442 22.559 -19.256 -2.828 1.00 58.39 O ANISOU 42 O VAL A 442 5557 5551 11080 614 -682 -1870 O ATOM 43 CB VAL A 442 19.999 -17.067 -2.862 1.00 49.64 C ANISOU 43 CB VAL A 442 4561 4826 9475 592 -487 -1757 C ATOM 44 CG1 VAL A 442 20.988 -16.567 -1.697 1.00 47.00 C ANISOU 44 CG1 VAL A 442 4422 4546 8891 489 -285 -1384 C ATOM 45 CG2 VAL A 442 19.497 -15.907 -3.713 1.00 54.44 C ANISOU 45 CG2 VAL A 442 5286 5727 9671 727 -460 -1919 C ATOM 46 N CYS A 443 20.502 -19.972 -2.224 1.00 64.24 N ANISOU 46 N CYS A 443 5983 5972 12453 429 -761 -1736 N ATOM 47 CA CYS A 443 21.029 -20.928 -1.229 1.00 68.14 C ANISOU 47 CA CYS A 443 6363 6190 13336 292 -748 -1441 C ATOM 48 C CYS A 443 20.957 -22.452 -1.521 1.00 78.68 C ANISOU 48 C CYS A 443 7426 7108 15361 276 -1006 -1617 C ATOM 49 O CYS A 443 21.446 -23.237 -0.718 1.00 79.42 O ANISOU 49 O CYS A 443 7418 6966 15791 171 -995 -1347 O ATOM 50 CB CYS A 443 20.342 -20.667 0.104 1.00 48.87 C ANISOU 50 CB CYS A 443 3872 3765 10932 113 -558 -953 C ATOM 51 SG CYS A 443 18.749 -21.381 0.248 1.00 56.73 S ANISOU 51 SG CYS A 443 4534 4530 12491 -4 -675 -869 S ATOM 52 N SER A 444 20.352 -22.857 -2.635 1.00 70.61 N ANISOU 52 N SER A 444 6280 5989 14559 384 -1247 -2062 N ATOM 53 CA SER A 444 20.124 -24.277 -2.966 1.00 65.48 C ANISOU 53 CA SER A 444 5360 4898 14621 372 -1544 -2287 C ATOM 54 C SER A 444 19.106 -25.060 -2.144 1.00 78.88 C ANISOU 54 C SER A 444 6768 6241 16964 139 -1607 -1957 C ATOM 55 O SER A 444 19.018 -26.279 -2.281 1.00 90.76 O ANISOU 55 O SER A 444 8038 7316 19130 99 -1860 -2079 O ATOM 56 CB SER A 444 21.448 -25.066 -2.945 1.00 55.39 C ANISOU 56 CB SER A 444 4100 3438 13507 451 -1612 -2357 C ATOM 57 OG SER A 444 22.326 -24.447 -3.861 1.00 78.47 O ANISOU 57 OG SER A 444 7235 6701 15879 688 -1592 -2691 O ATOM 58 N ASP A 445 18.349 -24.398 -1.289 1.00 77.79 N ANISOU 58 N ASP A 445 6623 6274 16661 -6 -1390 -1532 N ATOM 59 CA ASP A 445 17.323 -25.080 -0.533 1.00 79.64 C ANISOU 59 CA ASP A 445 6546 6244 17471 -216 -1435 -1170 C ATOM 60 C ASP A 445 16.122 -25.223 -1.489 1.00 90.03 C ANISOU 60 C ASP A 445 7692 7482 19034 -195 -1673 -1532 C ATOM 61 O ASP A 445 16.229 -24.919 -2.681 1.00 79.91 O ANISOU 61 O ASP A 445 6532 6333 17498 -6 -1808 -2062 O ATOM 62 CB ASP A 445 16.971 -24.268 0.724 1.00 79.14 C ANISOU 62 CB ASP A 445 6530 6473 17066 -332 -1105 -596 C ATOM 63 CG ASP A 445 16.173 -25.064 1.763 1.00 85.60 C ANISOU 63 CG ASP A 445 6994 7065 18464 -549 -1099 -69 C ATOM 64 OD1 ASP A 445 15.994 -26.296 1.599 1.00 95.02 O ANISOU 64 OD1 ASP A 445 7904 7813 20386 -644 -1354 -97 O ATOM 65 OD2 ASP A 445 15.715 -24.442 2.752 1.00 82.04 O ANISOU 65 OD2 ASP A 445 6535 6896 17742 -614 -845 383 O ATOM 66 N GLU A 446 14.997 -25.708 -0.983 1.00 94.43 N ANISOU 66 N GLU A 446 7944 7847 20087 -382 -1733 -1234 N ATOM 67 CA GLU A 446 13.824 -25.929 -1.825 1.00100.98 C ANISOU 67 CA GLU A 446 8572 8578 21219 -391 -1983 -1545 C ATOM 68 C GLU A 446 13.118 -24.608 -2.037 1.00 86.74 C ANISOU 68 C GLU A 446 6924 7251 18780 -309 -1787 -1556 C ATOM 69 O GLU A 446 12.580 -24.027 -1.091 1.00 87.99 O ANISOU 69 O GLU A 446 7062 7623 18746 -402 -1532 -1075 O ATOM 70 CB GLU A 446 12.879 -26.922 -1.159 1.00108.81 C ANISOU 70 CB GLU A 446 9148 9194 23002 -642 -2118 -1156 C ATOM 71 CG GLU A 446 11.707 -27.351 -2.010 1.00128.44 C ANISOU 71 CG GLU A 446 11374 11494 25935 -685 -2439 -1477 C ATOM 72 CD GLU A 446 10.505 -27.701 -1.163 1.00142.58 C ANISOU 72 CD GLU A 446 12790 13172 28213 -938 -2419 -914 C ATOM 73 OE1 GLU A 446 10.348 -27.082 -0.090 1.00136.35 O ANISOU 73 OE1 GLU A 446 12026 12688 27093 -999 -2076 -348 O ATOM 74 OE2 GLU A 446 9.720 -28.587 -1.562 1.00159.24 O ANISOU 74 OE2 GLU A 446 14568 14905 31030 -1067 -2754 -1034 O ATOM 75 N ALA A 447 13.134 -24.127 -3.274 1.00 78.92 N ANISOU 75 N ALA A 447 6083 6450 17454 -111 -1905 -2099 N ATOM 76 CA ALA A 447 12.476 -22.864 -3.617 1.00 82.41 C ANISOU 76 CA ALA A 447 6670 7332 17310 -9 -1744 -2143 C ATOM 77 C ALA A 447 10.961 -22.960 -3.467 1.00 95.36 C ANISOU 77 C ALA A 447 8021 8945 19265 -141 -1806 -1969 C ATOM 78 O ALA A 447 10.383 -24.016 -3.713 1.00 96.76 O ANISOU 78 O ALA A 447 7888 8769 20107 -257 -2096 -2075 O ATOM 79 CB ALA A 447 12.834 -22.473 -5.037 1.00 80.01 C ANISOU 79 CB ALA A 447 6529 7232 16638 237 -1888 -2744 C ATOM 80 N SER A 448 10.331 -21.854 -3.064 1.00 96.63 N ANISOU 80 N SER A 448 8276 9474 18963 -117 -1546 -1704 N ATOM 81 CA SER A 448 8.877 -21.791 -2.875 1.00 96.85 C ANISOU 81 CA SER A 448 8037 9562 19198 -216 -1558 -1493 C ATOM 82 C SER A 448 8.197 -20.898 -3.909 1.00 93.45 C ANISOU 82 C SER A 448 7691 9456 18359 -45 -1590 -1839 C ATOM 83 O SER A 448 7.069 -20.464 -3.708 1.00 98.56 O ANISOU 83 O SER A 448 8200 10282 18965 -74 -1512 -1634 O ATOM 84 CB SER A 448 8.533 -21.284 -1.461 1.00 88.85 C ANISOU 84 CB SER A 448 7006 8740 18013 -306 -1224 -854 C ATOM 85 OG SER A 448 8.802 -19.892 -1.286 1.00 76.83 O ANISOU 85 OG SER A 448 5827 7629 15737 -139 -936 -815 O ATOM 86 N GLY A 449 8.892 -20.617 -5.004 1.00 88.12 N ANISOU 86 N GLY A 449 7227 8888 17368 147 -1695 -2336 N ATOM 87 CA GLY A 449 8.380 -19.746 -6.040 1.00 79.96 C ANISOU 87 CA GLY A 449 6279 8198 15906 334 -1721 -2653 C ATOM 88 C GLY A 449 9.315 -18.595 -6.368 1.00 74.37 C ANISOU 88 C GLY A 449 5949 7825 14482 539 -1517 -2751 C ATOM 89 O GLY A 449 10.481 -18.515 -5.910 1.00 69.58 O ANISOU 89 O GLY A 449 5555 7179 13704 545 -1386 -2644 O ATOM 90 N ACYS A 450 8.800 -17.648 -7.134 0.61 58.83 N ANISOU 90 N ACYS A 450 4059 6201 12094 703 -1483 -2913 N ATOM 91 N BCYS A 450 8.838 -17.706 -7.222 0.39 61.24 N ANISOU 91 N BCYS A 450 4358 6499 12412 710 -1506 -2952 N ATOM 92 CA ACYS A 450 9.612 -16.542 -7.641 0.61 63.44 C ANISOU 92 CA ACYS A 450 4959 7107 12038 905 -1332 -3018 C ATOM 93 CA BCYS A 450 9.622 -16.535 -7.562 0.39 62.24 C ANISOU 93 CA BCYS A 450 4812 6947 11889 896 -1319 -2991 C ATOM 94 C ACYS A 450 9.387 -15.267 -6.826 0.61 58.26 C ANISOU 94 C ACYS A 450 4507 6668 10961 915 -1007 -2617 C ATOM 95 C BCYS A 450 9.340 -15.454 -6.549 0.39 58.74 C ANISOU 95 C BCYS A 450 4534 6659 11125 865 -999 -2544 C ATOM 96 O ACYS A 450 8.300 -14.701 -6.882 0.61 64.99 O ANISOU 96 O ACYS A 450 5281 7690 11720 951 -954 -2530 O ATOM 97 O BCYS A 450 8.193 -15.233 -6.177 0.39 60.09 O ANISOU 97 O BCYS A 450 4563 6890 11379 818 -939 -2348 O ATOM 98 CB ACYS A 450 9.256 -16.316 -9.111 0.61 69.63 C ANISOU 98 CB ACYS A 450 5683 8152 12623 1109 -1524 -3465 C ATOM 99 CB BCYS A 450 9.311 -16.055 -8.975 0.39 66.57 C ANISOU 99 CB BCYS A 450 5350 7807 12135 1115 -1455 -3388 C ATOM 100 SG ACYS A 450 10.140 -15.016 -9.960 0.61 90.14 S ANISOU 100 SG ACYS A 450 8585 11185 14480 1372 -1383 -3580 S ATOM 101 SG BCYS A 450 9.958 -17.174 -10.228 0.39 67.43 S ANISOU 101 SG BCYS A 450 5331 7826 12462 1239 -1819 -3989 S ATOM 102 N HIS A 451 10.399 -14.815 -6.065 1.00 49.32 N ANISOU 102 N HIS A 451 3629 5528 9582 895 -804 -2386 N ATOM 103 CA HIS A 451 10.248 -13.622 -5.227 1.00 47.51 C ANISOU 103 CA HIS A 451 3605 5472 8974 917 -524 -2047 C ATOM 104 C HIS A 451 11.240 -12.551 -5.645 1.00 46.75 C ANISOU 104 C HIS A 451 3825 5573 8363 1060 -422 -2112 C ATOM 105 O HIS A 451 12.393 -12.866 -5.944 1.00 48.46 O ANISOU 105 O HIS A 451 4135 5735 8542 1070 -482 -2241 O ATOM 106 CB HIS A 451 10.452 -13.983 -3.753 1.00 53.18 C ANISOU 106 CB HIS A 451 4317 6016 9873 750 -374 -1659 C ATOM 107 CG HIS A 451 9.768 -15.259 -3.366 1.00 60.28 C ANISOU 107 CG HIS A 451 4872 6668 11364 580 -505 -1557 C ATOM 108 ND1 HIS A 451 8.406 -15.337 -3.160 1.00 55.88 N ANISOU 108 ND1 HIS A 451 4067 6158 11006 537 -508 -1406 N ATOM 109 CD2 HIS A 451 10.246 -16.513 -3.196 1.00 50.60 C ANISOU 109 CD2 HIS A 451 3485 5133 10606 443 -655 -1574 C ATOM 110 CE1 HIS A 451 8.078 -16.585 -2.868 1.00 55.35 C ANISOU 110 CE1 HIS A 451 3692 5815 11522 362 -659 -1313 C ATOM 111 NE2 HIS A 451 9.180 -17.314 -2.859 1.00 63.95 N ANISOU 111 NE2 HIS A 451 4835 6669 12796 302 -751 -1410 N ATOM 112 N TYR A 452 10.771 -11.300 -5.707 1.00 43.40 N ANISOU 112 N TYR A 452 3544 5377 7570 1176 -283 -2017 N ATOM 113 CA TYR A 452 11.636 -10.197 -6.088 1.00 54.44 C ANISOU 113 CA TYR A 452 5221 6942 8522 1298 -195 -2026 C ATOM 114 C TYR A 452 12.385 -10.558 -7.344 1.00 50.77 C ANISOU 114 C TYR A 452 4723 6569 7998 1394 -367 -2338 C ATOM 115 O TYR A 452 13.528 -10.161 -7.521 1.00 47.57 O ANISOU 115 O TYR A 452 4498 6224 7352 1433 -329 -2323 O ATOM 116 CB TYR A 452 12.609 -9.840 -4.911 1.00 41.18 C ANISOU 116 CB TYR A 452 3779 5151 6717 1202 -29 -1760 C ATOM 117 CG TYR A 452 11.795 -9.536 -3.668 1.00 43.19 C ANISOU 117 CG TYR A 452 4034 5374 7002 1149 133 -1478 C ATOM 118 CD1 TYR A 452 10.841 -8.538 -3.695 1.00 44.92 C ANISOU 118 CD1 TYR A 452 4297 5756 7015 1274 224 -1418 C ATOM 119 CD2 TYR A 452 11.925 -10.287 -2.512 1.00 46.40 C ANISOU 119 CD2 TYR A 452 4364 5620 7644 1000 191 -1269 C ATOM 120 CE1 TYR A 452 10.031 -8.270 -2.600 1.00 50.65 C ANISOU 120 CE1 TYR A 452 4997 6505 7742 1270 372 -1180 C ATOM 121 CE2 TYR A 452 11.181 -10.001 -1.402 1.00 37.42 C ANISOU 121 CE2 TYR A 452 3200 4529 6487 988 345 -1003 C ATOM 122 CZ TYR A 452 10.193 -9.018 -1.467 1.00 46.36 C ANISOU 122 CZ TYR A 452 4371 5843 7401 1131 432 -974 C ATOM 123 OH TYR A 452 9.407 -8.753 -0.389 1.00 40.76 O ANISOU 123 OH TYR A 452 3613 5223 6651 1158 585 -725 O ATOM 124 N GLY A 453 11.734 -11.310 -8.219 1.00 53.10 N ANISOU 124 N GLY A 453 4771 6897 8508 1444 -566 -2623 N ATOM 125 CA GLY A 453 12.241 -11.559 -9.553 1.00 51.85 C ANISOU 125 CA GLY A 453 4552 6920 8230 1603 -741 -2970 C ATOM 126 C GLY A 453 13.065 -12.815 -9.681 1.00 56.92 C ANISOU 126 C GLY A 453 5102 7369 9157 1558 -907 -3190 C ATOM 127 O GLY A 453 13.554 -13.132 -10.760 1.00 65.56 O ANISOU 127 O GLY A 453 6132 8626 10151 1718 -1064 -3512 O ATOM 128 N VAL A 454 13.227 -13.564 -8.598 1.00 57.09 N ANISOU 128 N VAL A 454 5099 7058 9534 1362 -878 -3020 N ATOM 129 CA VAL A 454 14.108 -14.719 -8.647 1.00 56.83 C ANISOU 129 CA VAL A 454 4997 6810 9785 1326 -1023 -3196 C ATOM 130 C VAL A 454 13.546 -15.951 -7.968 1.00 55.19 C ANISOU 130 C VAL A 454 4565 6223 10184 1139 -1142 -3163 C ATOM 131 O VAL A 454 12.967 -15.880 -6.894 1.00 59.84 O ANISOU 131 O VAL A 454 5126 6678 10931 976 -1008 -2817 O ATOM 132 CB VAL A 454 15.455 -14.374 -7.934 1.00 47.44 C ANISOU 132 CB VAL A 454 4049 5591 8385 1274 -848 -2945 C ATOM 133 CG1 VAL A 454 16.427 -15.562 -8.014 1.00 49.09 C ANISOU 133 CG1 VAL A 454 4185 5594 8875 1263 -992 -3122 C ATOM 134 CG2 VAL A 454 16.070 -13.147 -8.581 1.00 54.28 C ANISOU 134 CG2 VAL A 454 5116 6806 8700 1435 -743 -2925 C ATOM 135 N LEU A 455 13.772 -17.091 -8.583 1.00 54.44 N ANISOU 135 N LEU A 455 4297 5955 10432 1175 -1400 -3512 N ATOM 136 CA LEU A 455 13.337 -18.345 -8.025 1.00 59.38 C ANISOU 136 CA LEU A 455 4686 6168 11707 993 -1556 -3487 C ATOM 137 C LEU A 455 14.117 -18.494 -6.736 1.00 68.19 C ANISOU 137 C LEU A 455 5915 7086 12909 831 -1365 -3076 C ATOM 138 O LEU A 455 15.348 -18.664 -6.785 1.00 56.04 O ANISOU 138 O LEU A 455 4509 5531 11253 890 -1351 -3136 O ATOM 139 CB LEU A 455 13.665 -19.454 -9.015 1.00 79.04 C ANISOU 139 CB LEU A 455 7016 8510 14505 1108 -1888 -4000 C ATOM 140 CG LEU A 455 12.822 -20.719 -8.960 1.00100.77 C ANISOU 140 CG LEU A 455 9450 10857 17983 968 -2172 -4142 C ATOM 141 CD1 LEU A 455 13.339 -21.754 -9.963 1.00104.97 C ANISOU 141 CD1 LEU A 455 9868 11239 18776 1129 -2516 -4715 C ATOM 142 CD2 LEU A 455 12.845 -21.274 -7.568 1.00106.46 C ANISOU 142 CD2 LEU A 455 10102 11211 19137 704 -2062 -3666 C ATOM 143 N THR A 456 13.436 -18.381 -5.589 1.00 60.29 N ANISOU 143 N THR A 456 4857 5987 12063 648 -1208 -2648 N ATOM 144 CA THR A 456 14.110 -18.491 -4.281 1.00 64.16 C ANISOU 144 CA THR A 456 5433 6343 12602 503 -1016 -2227 C ATOM 145 C THR A 456 13.249 -19.208 -3.264 1.00 68.97 C ANISOU 145 C THR A 456 5782 6710 13712 295 -1009 -1872 C ATOM 146 O THR A 456 12.023 -19.371 -3.457 1.00 66.13 O ANISOU 146 O THR A 456 5201 6330 13596 251 -1102 -1884 O ATOM 147 CB THR A 456 14.399 -17.116 -3.661 1.00 58.56 C ANISOU 147 CB THR A 456 5011 5928 11310 538 -718 -1944 C ATOM 148 OG1 THR A 456 13.164 -16.407 -3.486 1.00 55.83 O ANISOU 148 OG1 THR A 456 4619 5748 10844 543 -622 -1808 O ATOM 149 CG2 THR A 456 15.306 -16.307 -4.547 1.00 50.46 C ANISOU 149 CG2 THR A 456 4233 5150 9791 718 -700 -2185 C ATOM 150 N CYS A 457 13.876 -19.633 -2.168 1.00 58.73 N ANISOU 150 N CYS A 457 4487 5258 12570 168 -895 -1521 N ATOM 151 CA CYS A 457 13.118 -20.142 -1.024 1.00 54.26 C ANISOU 151 CA CYS A 457 3674 4554 12387 -19 -823 -1060 C ATOM 152 C CYS A 457 12.574 -18.980 -0.198 1.00 52.97 C ANISOU 152 C CYS A 457 3632 4731 11765 2 -533 -718 C ATOM 153 O CYS A 457 12.921 -17.785 -0.443 1.00 48.38 O ANISOU 153 O CYS A 457 3354 4432 10597 145 -393 -834 O ATOM 154 CB CYS A 457 13.957 -21.057 -0.148 1.00 71.19 C ANISOU 154 CB CYS A 457 5741 6438 14870 -148 -811 -780 C ATOM 155 SG CYS A 457 15.274 -20.153 0.688 1.00 60.93 S ANISOU 155 SG CYS A 457 4801 5394 12955 -94 -519 -551 S ATOM 156 N GLY A 458 11.711 -19.332 0.764 1.00 65.82 N ANISOU 156 N GLY A 458 5004 6332 13672 -128 -454 -295 N ATOM 157 CA GLY A 458 11.015 -18.368 1.608 1.00 65.42 C ANISOU 157 CA GLY A 458 5001 6614 13243 -85 -195 35 C ATOM 158 C GLY A 458 11.992 -17.659 2.558 1.00 64.85 C ANISOU 158 C GLY A 458 5211 6730 12697 -37 47 249 C ATOM 159 O GLY A 458 11.818 -16.480 2.887 1.00 51.68 O ANISOU 159 O GLY A 458 3756 5364 10517 85 235 299 O ATOM 160 N SER A 459 13.004 -18.371 3.034 1.00 54.61 N ANISOU 160 N SER A 459 3911 5253 11584 -128 32 376 N ATOM 161 CA SER A 459 13.999 -17.708 3.909 1.00 55.43 C ANISOU 161 CA SER A 459 4281 5545 11234 -88 236 554 C ATOM 162 C SER A 459 14.827 -16.639 3.176 1.00 54.55 C ANISOU 162 C SER A 459 4558 5563 10604 51 251 194 C ATOM 163 O SER A 459 15.063 -15.564 3.703 1.00 44.52 O ANISOU 163 O SER A 459 3530 4534 8850 131 421 272 O ATOM 164 CB SER A 459 14.906 -18.714 4.598 1.00 56.34 C ANISOU 164 CB SER A 459 4288 5462 11658 -213 220 801 C ATOM 165 OG SER A 459 15.771 -19.393 3.699 1.00 73.68 O ANISOU 165 OG SER A 459 6521 7375 14101 -226 18 476 O ATOM 166 N CYS A 460 15.246 -16.922 1.954 1.00 42.71 N ANISOU 166 N CYS A 460 3102 3913 9213 89 62 -197 N ATOM 167 CA CYS A 460 15.972 -15.925 1.178 1.00 39.59 C ANISOU 167 CA CYS A 460 3023 3672 8347 223 71 -490 C ATOM 168 C CYS A 460 15.082 -14.770 0.761 1.00 48.84 C ANISOU 168 C CYS A 460 4302 5075 9179 346 135 -596 C ATOM 169 O CYS A 460 15.551 -13.647 0.657 1.00 45.43 O ANISOU 169 O CYS A 460 4148 4819 8295 440 227 -654 O ATOM 170 CB CYS A 460 16.642 -16.567 -0.027 1.00 43.43 C ANISOU 170 CB CYS A 460 3491 4002 9009 268 -142 -865 C ATOM 171 SG CYS A 460 18.055 -17.707 0.480 1.00 52.98 S ANISOU 171 SG CYS A 460 4659 4963 10507 168 -192 -751 S ATOM 172 N LYS A 461 13.782 -15.027 0.580 1.00 48.10 N ANISOU 172 N LYS A 461 3977 4976 9322 341 87 -588 N ATOM 173 CA LYS A 461 12.826 -13.957 0.239 1.00 43.42 C ANISOU 173 CA LYS A 461 3456 4614 8428 469 156 -655 C ATOM 174 C LYS A 461 12.807 -12.884 1.320 1.00 47.97 C ANISOU 174 C LYS A 461 4232 5400 8594 526 391 -395 C ATOM 175 O LYS A 461 12.971 -11.698 1.040 1.00 42.79 O ANISOU 175 O LYS A 461 3835 4898 7524 654 457 -509 O ATOM 176 CB LYS A 461 11.400 -14.536 0.138 1.00 43.56 C ANISOU 176 CB LYS A 461 3140 4597 8813 426 81 -596 C ATOM 177 CG LYS A 461 10.242 -13.456 0.132 1.00 45.90 C ANISOU 177 CG LYS A 461 3466 5163 8811 558 202 -548 C ATOM 178 CD LYS A 461 8.906 -14.177 0.002 1.00 60.09 C ANISOU 178 CD LYS A 461 4888 6918 11024 490 104 -472 C ATOM 179 CE LYS A 461 8.427 -14.634 1.365 1.00 80.54 C ANISOU 179 CE LYS A 461 7261 9527 13811 385 243 -3 C ATOM 180 NZ LYS A 461 6.934 -14.654 1.462 1.00 79.76 N ANISOU 180 NZ LYS A 461 6870 9566 13868 394 260 171 N ATOM 181 N VAL A 462 12.571 -13.287 2.569 1.00 45.36 N ANISOU 181 N VAL A 462 3764 5087 8382 446 509 -41 N ATOM 182 CA VAL A 462 12.419 -12.287 3.627 1.00 37.86 C ANISOU 182 CA VAL A 462 2977 4381 7029 540 720 172 C ATOM 183 C VAL A 462 13.864 -11.757 4.069 1.00 31.54 C ANISOU 183 C VAL A 462 2494 3585 5903 539 775 157 C ATOM 184 O VAL A 462 14.005 -10.585 4.452 1.00 41.35 O ANISOU 184 O VAL A 462 3992 4989 6729 654 879 140 O ATOM 185 CB VAL A 462 11.661 -12.863 4.823 1.00 51.29 C ANISOU 185 CB VAL A 462 4395 6179 8912 489 837 577 C ATOM 186 CG1 VAL A 462 12.484 -14.002 5.514 1.00 51.94 C ANISOU 186 CG1 VAL A 462 4334 6102 9300 320 817 818 C ATOM 187 CG2 VAL A 462 11.329 -11.779 5.787 1.00 57.92 C ANISOU 187 CG2 VAL A 462 5384 7324 9297 647 1039 728 C ATOM 188 N PHE A 463 14.876 -12.596 3.954 1.00 36.41 N ANISOU 188 N PHE A 463 3084 4018 6731 418 686 144 N ATOM 189 CA PHE A 463 16.264 -12.073 4.171 1.00 31.25 C ANISOU 189 CA PHE A 463 2719 3376 5779 412 712 103 C ATOM 190 C PHE A 463 16.559 -10.873 3.250 1.00 39.14 C ANISOU 190 C PHE A 463 4000 4439 6434 526 676 -175 C ATOM 191 O PHE A 463 16.999 -9.803 3.691 1.00 38.71 O ANISOU 191 O PHE A 463 4202 4489 6016 583 751 -157 O ATOM 192 CB PHE A 463 17.295 -13.172 3.950 1.00 33.98 C ANISOU 192 CB PHE A 463 2979 3515 6417 289 603 91 C ATOM 193 CG PHE A 463 18.739 -12.616 3.956 1.00 38.45 C ANISOU 193 CG PHE A 463 3825 4106 6679 285 608 28 C ATOM 194 CD1 PHE A 463 19.357 -12.226 2.788 1.00 40.08 C ANISOU 194 CD1 PHE A 463 4177 4291 6762 340 505 -249 C ATOM 195 CD2 PHE A 463 19.375 -12.372 5.164 1.00 35.09 C ANISOU 195 CD2 PHE A 463 3502 3777 6054 242 720 265 C ATOM 196 CE1 PHE A 463 20.694 -11.692 2.828 1.00 39.15 C ANISOU 196 CE1 PHE A 463 4286 4213 6375 322 509 -255 C ATOM 197 CE2 PHE A 463 20.736 -11.833 5.192 1.00 35.84 C ANISOU 197 CE2 PHE A 463 3843 3895 5881 220 707 219 C ATOM 198 CZ PHE A 463 21.341 -11.504 4.025 1.00 39.55 C ANISOU 198 CZ PHE A 463 4436 4317 6276 253 603 -25 C ATOM 199 N PHE A 464 16.298 -11.051 1.959 1.00 36.68 N ANISOU 199 N PHE A 464 3622 4065 6249 565 546 -426 N ATOM 200 CA PHE A 464 16.537 -9.990 1.000 1.00 35.21 C ANISOU 200 CA PHE A 464 3648 3964 5765 679 508 -641 C ATOM 201 C PHE A 464 15.743 -8.728 1.291 1.00 43.58 C ANISOU 201 C PHE A 464 4852 5172 6533 803 614 -605 C ATOM 202 O PHE A 464 16.252 -7.613 1.237 1.00 36.09 O ANISOU 202 O PHE A 464 4158 4275 5278 865 639 -639 O ATOM 203 CB PHE A 464 16.190 -10.448 -0.408 1.00 39.33 C ANISOU 203 CB PHE A 464 4022 4463 6460 732 355 -909 C ATOM 204 CG PHE A 464 16.459 -9.396 -1.435 1.00 45.79 C ANISOU 204 CG PHE A 464 5018 5414 6966 859 322 -1081 C ATOM 205 CD1 PHE A 464 17.760 -9.031 -1.733 1.00 37.59 C ANISOU 205 CD1 PHE A 464 4155 4396 5733 853 299 -1104 C ATOM 206 CD2 PHE A 464 15.434 -8.739 -2.069 1.00 41.03 C ANISOU 206 CD2 PHE A 464 4392 4935 6263 984 318 -1175 C ATOM 207 CE1 PHE A 464 18.022 -8.063 -2.681 1.00 41.63 C ANISOU 207 CE1 PHE A 464 4794 5046 5977 965 269 -1199 C ATOM 208 CE2 PHE A 464 15.705 -7.730 -3.017 1.00 47.03 C ANISOU 208 CE2 PHE A 464 5298 5832 6740 1106 292 -1282 C ATOM 209 CZ PHE A 464 16.994 -7.403 -3.306 1.00 43.77 C ANISOU 209 CZ PHE A 464 5040 5434 6156 1091 268 -1279 C ATOM 210 N LYS A 465 14.499 -8.910 1.682 1.00 36.26 N ANISOU 210 N LYS A 465 3750 4307 5721 839 674 -512 N ATOM 211 CA LYS A 465 13.596 -7.775 1.884 1.00 38.87 C ANISOU 211 CA LYS A 465 4183 4789 5796 995 770 -498 C ATOM 212 C LYS A 465 14.092 -6.977 3.057 1.00 46.09 C ANISOU 212 C LYS A 465 5329 5765 6419 1030 885 -368 C ATOM 213 O LYS A 465 14.149 -5.731 3.051 1.00 43.29 O ANISOU 213 O LYS A 465 5219 5456 5773 1151 911 -443 O ATOM 214 CB LYS A 465 12.175 -8.339 2.170 1.00 38.39 C ANISOU 214 CB LYS A 465 3826 4807 5954 1016 814 -377 C ATOM 215 CG LYS A 465 11.114 -7.250 2.584 1.00 47.48 C ANISOU 215 CG LYS A 465 5044 6154 6843 1206 941 -323 C ATOM 216 CD LYS A 465 11.103 -6.098 1.534 1.00 45.64 C ANISOU 216 CD LYS A 465 5024 5938 6380 1344 889 -548 C ATOM 217 CE LYS A 465 9.831 -5.214 1.598 1.00 74.72 C ANISOU 217 CE LYS A 465 8699 9789 9904 1546 977 -532 C ATOM 218 NZ LYS A 465 8.988 -5.539 2.739 1.00 67.50 N ANISOU 218 NZ LYS A 465 7607 9019 9023 1583 1108 -309 N ATOM 219 N ARG A 466 14.523 -7.713 4.070 1.00 37.46 N ANISOU 219 N ARG A 466 4153 4663 5417 924 937 -176 N ATOM 220 CA ARG A 466 15.057 -7.090 5.280 1.00 44.15 C ANISOU 220 CA ARG A 466 5191 5602 5981 957 1031 -61 C ATOM 221 C ARG A 466 16.395 -6.395 4.983 1.00 41.39 C ANISOU 221 C ARG A 466 5137 5150 5442 913 953 -190 C ATOM 222 O ARG A 466 16.642 -5.291 5.430 1.00 46.30 O ANISOU 222 O ARG A 466 6002 5810 5779 998 972 -236 O ATOM 223 CB ARG A 466 15.290 -8.163 6.317 1.00 50.86 C ANISOU 223 CB ARG A 466 5844 6487 6993 843 1093 200 C ATOM 224 CG ARG A 466 14.008 -8.526 7.022 1.00 60.71 C ANISOU 224 CG ARG A 466 6828 7915 8323 915 1209 416 C ATOM 225 CD ARG A 466 14.135 -9.811 7.790 1.00 60.98 C ANISOU 225 CD ARG A 466 6577 7954 8637 776 1246 723 C ATOM 226 NE ARG A 466 12.863 -10.115 8.455 1.00 63.13 N ANISOU 226 NE ARG A 466 6561 8438 8987 849 1362 985 N ATOM 227 CZ ARG A 466 12.518 -11.320 8.897 1.00 63.32 C ANISOU 227 CZ ARG A 466 6227 8458 9374 728 1381 1303 C ATOM 228 NH1 ARG A 466 13.329 -12.362 8.730 1.00 48.45 N ANISOU 228 NH1 ARG A 466 4242 6336 7830 537 1284 1368 N ATOM 229 NH2 ARG A 466 11.352 -11.480 9.478 1.00 64.70 N ANISOU 229 NH2 ARG A 466 6131 8861 9591 804 1492 1569 N ATOM 230 N ALA A 467 17.240 -7.063 4.217 1.00 35.40 N ANISOU 230 N ALA A 467 4334 4259 4858 787 852 -248 N ATOM 231 CA ALA A 467 18.570 -6.488 3.917 1.00 36.58 C ANISOU 231 CA ALA A 467 4717 4338 4842 733 778 -319 C ATOM 232 C ALA A 467 18.450 -5.238 3.029 1.00 48.98 C ANISOU 232 C ALA A 467 6476 5905 6228 841 725 -475 C ATOM 233 O ALA A 467 19.136 -4.250 3.233 1.00 50.47 O ANISOU 233 O ALA A 467 6902 6063 6211 845 697 -485 O ATOM 234 CB ALA A 467 19.409 -7.518 3.239 1.00 32.38 C ANISOU 234 CB ALA A 467 4063 3709 4531 614 690 -345 C ATOM 235 N VAL A 468 17.524 -5.273 2.086 1.00 50.93 N ANISOU 235 N VAL A 468 6602 6183 6567 930 704 -581 N ATOM 236 CA VAL A 468 17.368 -4.204 1.126 1.00 52.87 C ANISOU 236 CA VAL A 468 6976 6444 6668 1039 653 -694 C ATOM 237 C VAL A 468 16.682 -2.970 1.706 1.00 58.36 C ANISOU 237 C VAL A 468 7846 7163 7164 1180 716 -687 C ATOM 238 O VAL A 468 17.017 -1.849 1.334 1.00 61.65 O ANISOU 238 O VAL A 468 8459 7528 7435 1235 665 -724 O ATOM 239 CB VAL A 468 16.631 -4.724 -0.128 1.00 50.71 C ANISOU 239 CB VAL A 468 6488 6231 6548 1098 597 -819 C ATOM 240 CG1 VAL A 468 15.127 -4.522 0.005 1.00 48.47 C ANISOU 240 CG1 VAL A 468 6101 6028 6287 1224 664 -827 C ATOM 241 CG2 VAL A 468 17.121 -4.044 -1.332 1.00 51.57 C ANISOU 241 CG2 VAL A 468 6678 6380 6535 1154 513 -901 C ATOM 242 N GLU A 469 15.763 -3.167 2.656 1.00 49.15 N ANISOU 242 N GLU A 469 6600 6078 5999 1247 820 -626 N ATOM 243 CA GLU A 469 14.978 -2.094 3.218 1.00 62.33 C ANISOU 243 CA GLU A 469 8403 7803 7478 1429 885 -647 C ATOM 244 C GLU A 469 15.661 -1.447 4.416 1.00 63.22 C ANISOU 244 C GLU A 469 8746 7887 7388 1438 897 -627 C ATOM 245 O GLU A 469 15.424 -0.293 4.728 1.00 78.46 O ANISOU 245 O GLU A 469 10876 9792 9142 1587 889 -709 O ATOM 246 CB GLU A 469 13.589 -2.624 3.603 1.00 68.57 C ANISOU 246 CB GLU A 469 8956 8752 8346 1529 994 -580 C ATOM 247 CG GLU A 469 12.481 -1.619 3.394 1.00 87.45 C ANISOU 247 CG GLU A 469 11400 11219 10608 1754 1035 -650 C ATOM 248 CD GLU A 469 12.085 -1.458 1.946 1.00 97.80 C ANISOU 248 CD GLU A 469 12640 12507 12013 1785 960 -743 C ATOM 249 OE1 GLU A 469 12.563 -0.493 1.307 1.00100.19 O ANISOU 249 OE1 GLU A 469 13141 12713 12213 1828 886 -819 O ATOM 250 OE2 GLU A 469 11.287 -2.289 1.454 1.00101.91 O ANISOU 250 OE2 GLU A 469 12891 13115 12715 1767 965 -728 O ATOM 251 N GLY A 470 16.516 -2.169 5.109 1.00 52.68 N ANISOU 251 N GLY A 470 7383 6554 6078 1291 902 -533 N ATOM 252 CA GLY A 470 17.292 -1.525 6.142 1.00 64.51 C ANISOU 252 CA GLY A 470 9104 8035 7372 1290 880 -541 C ATOM 253 C GLY A 470 18.707 -1.217 5.642 1.00 72.98 C ANISOU 253 C GLY A 470 10340 8935 8454 1127 745 -565 C ATOM 254 O GLY A 470 18.940 -0.945 4.455 1.00 65.83 O ANISOU 254 O GLY A 470 9453 7931 7629 1094 667 -605 O ATOM 255 N GLN A 471 19.661 -1.263 6.559 1.00 82.87 N ANISOU 255 N GLN A 471 11690 10188 9610 1033 718 -517 N ATOM 256 CA GLN A 471 21.060 -1.275 6.187 1.00 84.17 C ANISOU 256 CA GLN A 471 11938 10232 9811 847 605 -480 C ATOM 257 C GLN A 471 21.457 -2.724 5.938 1.00 81.01 C ANISOU 257 C GLN A 471 11300 9881 9597 707 647 -354 C ATOM 258 O GLN A 471 20.867 -3.658 6.518 1.00 74.19 O ANISOU 258 O GLN A 471 10245 9131 8814 723 752 -264 O ATOM 259 CB GLN A 471 21.943 -0.710 7.301 1.00 95.85 C ANISOU 259 CB GLN A 471 13613 11695 11112 800 538 -490 C ATOM 260 CG GLN A 471 22.004 0.803 7.363 1.00106.09 C ANISOU 260 CG GLN A 471 15181 12841 12288 887 414 -640 C ATOM 261 CD GLN A 471 21.330 1.356 8.596 1.00114.09 C ANISOU 261 CD GLN A 471 16301 13954 13093 1081 448 -767 C ATOM 262 OE1 GLN A 471 21.869 2.242 9.268 1.00113.62 O ANISOU 262 OE1 GLN A 471 16458 13809 12903 1100 322 -888 O ATOM 263 NE2 GLN A 471 20.148 0.829 8.912 1.00118.28 N ANISOU 263 NE2 GLN A 471 16665 14683 13592 1238 608 -743 N ATOM 264 N HIS A 472 22.447 -2.899 5.063 1.00 64.46 N ANISOU 264 N HIS A 472 9203 7704 7584 583 560 -334 N ATOM 265 CA HIS A 472 23.095 -4.189 4.864 1.00 59.26 C ANISOU 265 CA HIS A 472 8357 7065 7093 458 568 -240 C ATOM 266 C HIS A 472 24.632 -3.973 5.007 1.00 60.13 C ANISOU 266 C HIS A 472 8587 7135 7126 312 479 -164 C ATOM 267 O HIS A 472 25.382 -4.212 4.060 1.00 47.28 O ANISOU 267 O HIS A 472 6909 5488 5567 251 417 -149 O ATOM 268 CB HIS A 472 22.740 -4.781 3.494 1.00 49.68 C ANISOU 268 CB HIS A 472 6971 5843 6062 489 545 -316 C ATOM 269 CG HIS A 472 22.694 -3.762 2.391 1.00 60.41 C ANISOU 269 CG HIS A 472 8435 7184 7333 561 474 -405 C ATOM 270 ND1 HIS A 472 21.516 -3.200 1.946 1.00 62.03 N ANISOU 270 ND1 HIS A 472 8639 7409 7519 705 497 -498 N ATOM 271 CD2 HIS A 472 23.680 -3.202 1.644 1.00 60.19 C ANISOU 271 CD2 HIS A 472 8492 7142 7235 513 382 -377 C ATOM 272 CE1 HIS A 472 21.780 -2.335 0.977 1.00 69.41 C ANISOU 272 CE1 HIS A 472 9658 8335 8380 744 423 -520 C ATOM 273 NE2 HIS A 472 23.089 -2.298 0.792 1.00 59.19 N ANISOU 273 NE2 HIS A 472 8414 7023 7054 626 352 -435 N ATOM 274 N AASN A 473 24.973 -3.701 6.256 0.60 62.20 N ANISOU 274 N AASN A 473 8958 7429 7248 278 487 -109 N ATOM 275 N BASN A 473 25.093 -3.413 6.141 0.40 62.86 N ANISOU 275 N BASN A 473 9090 7489 7304 275 460 -126 N ATOM 276 CA AASN A 473 26.253 -3.233 6.747 0.60 63.96 C ANISOU 276 CA AASN A 473 9328 7624 7350 153 392 -50 C ATOM 277 CA BASN A 473 26.542 -3.127 6.360 0.40 59.16 C ANISOU 277 CA BASN A 473 8732 6985 6761 124 357 -46 C ATOM 278 C AASN A 473 27.049 -4.415 7.231 0.60 61.57 C ANISOU 278 C AASN A 473 8875 7397 7124 35 430 107 C ATOM 279 C BASN A 473 27.196 -4.300 7.069 0.40 60.32 C ANISOU 279 C BASN A 473 8735 7222 6963 23 409 101 C ATOM 280 O AASN A 473 27.541 -4.422 8.362 0.60 67.13 O ANISOU 280 O AASN A 473 9625 8177 7703 -15 430 183 O ATOM 281 O BASN A 473 27.715 -4.173 8.177 0.40 65.34 O ANISOU 281 O BASN A 473 9442 7921 7464 -30 396 164 O ATOM 282 CB AASN A 473 25.938 -2.406 7.971 0.60 51.74 C ANISOU 282 CB AASN A 473 7950 6110 5596 227 384 -119 C ATOM 283 CB BASN A 473 26.779 -1.849 7.197 0.40 44.06 C ANISOU 283 CB BASN A 473 7069 5018 4652 130 264 -114 C ATOM 284 CG AASN A 473 24.812 -3.033 8.795 0.60 48.12 C ANISOU 284 CG AASN A 473 7355 5813 5117 356 535 -96 C ATOM 285 CG BASN A 473 28.273 -1.430 7.263 0.40 49.24 C ANISOU 285 CG BASN A 473 7831 5613 5267 -48 119 -29 C ATOM 286 OD1AASN A 473 23.635 -2.908 8.456 0.60 60.32 O ANISOU 286 OD1AASN A 473 8851 7369 6699 495 601 -170 O ATOM 287 OD1BASN A 473 29.042 -1.608 6.310 0.40 38.53 O ANISOU 287 OD1BASN A 473 6406 4230 4004 -145 71 68 O ATOM 288 ND2AASN A 473 25.168 -3.702 9.890 0.60 55.19 N ANISOU 288 ND2AASN A 473 8165 6859 5947 315 591 36 N ATOM 289 ND2BASN A 473 28.671 -0.850 8.397 0.40 49.68 N ANISOU 289 ND2BASN A 473 8038 5669 5169 -78 41 -70 N ATOM 290 N TYR A 474 27.134 -5.448 6.418 1.00 50.47 N ANISOU 290 N TYR A 474 7274 5980 5922 11 458 146 N ATOM 291 CA TYR A 474 27.609 -6.704 6.951 1.00 53.90 C ANISOU 291 CA TYR A 474 7532 6463 6486 -66 510 297 C ATOM 292 C TYR A 474 29.080 -6.834 6.633 1.00 42.97 C ANISOU 292 C TYR A 474 6165 5071 5090 -188 428 379 C ATOM 293 O TYR A 474 29.533 -6.340 5.562 1.00 40.95 O ANISOU 293 O TYR A 474 5962 4782 4816 -192 348 318 O ATOM 294 CB TYR A 474 26.868 -7.828 6.241 1.00 50.50 C ANISOU 294 CB TYR A 474 6866 5987 6336 -13 558 267 C ATOM 295 CG TYR A 474 25.326 -7.794 6.337 1.00 46.65 C ANISOU 295 CG TYR A 474 6308 5511 5906 105 633 201 C ATOM 296 CD1 TYR A 474 24.679 -7.806 7.551 1.00 54.05 C ANISOU 296 CD1 TYR A 474 7218 6552 6769 143 728 310 C ATOM 297 CD2 TYR A 474 24.548 -7.837 5.190 1.00 44.80 C ANISOU 297 CD2 TYR A 474 6001 5223 5798 188 608 46 C ATOM 298 CE1 TYR A 474 23.284 -7.826 7.617 1.00 60.69 C ANISOU 298 CE1 TYR A 474 7958 7434 7666 256 803 284 C ATOM 299 CE2 TYR A 474 23.130 -7.862 5.255 1.00 41.48 C ANISOU 299 CE2 TYR A 474 5487 4825 5447 288 672 4 C ATOM 300 CZ TYR A 474 22.528 -7.850 6.458 1.00 55.97 C ANISOU 300 CZ TYR A 474 7294 6755 7215 318 771 133 C ATOM 301 OH TYR A 474 21.143 -7.867 6.499 1.00 56.55 O ANISOU 301 OH TYR A 474 7252 6882 7352 424 839 119 O ATOM 302 N LEU A 475 29.786 -7.622 7.436 1.00 41.33 N ANISOU 302 N LEU A 475 5867 4920 4916 -272 456 544 N ATOM 303 CA LEU A 475 31.194 -7.924 7.159 1.00 50.35 C ANISOU 303 CA LEU A 475 6984 6079 6068 -378 391 648 C ATOM 304 C LEU A 475 31.426 -9.410 6.972 1.00 47.11 C ANISOU 304 C LEU A 475 6336 5648 5917 -378 437 736 C ATOM 305 O LEU A 475 31.023 -10.209 7.765 1.00 49.74 O ANISOU 305 O LEU A 475 6539 5988 6372 -377 514 847 O ATOM 306 CB LEU A 475 32.074 -7.485 8.358 1.00 52.85 C ANISOU 306 CB LEU A 475 7413 6487 6183 -488 355 780 C ATOM 307 CG LEU A 475 31.840 -6.074 8.844 1.00 61.08 C ANISOU 307 CG LEU A 475 8693 7524 6992 -483 284 672 C ATOM 308 CD1 LEU A 475 32.404 -5.857 10.254 1.00 66.87 C ANISOU 308 CD1 LEU A 475 9497 8381 7530 -549 256 759 C ATOM 309 CD2 LEU A 475 32.476 -5.180 7.886 1.00 55.67 C ANISOU 309 CD2 LEU A 475 8123 6755 6275 -539 160 627 C ATOM 310 N CYS A 476 32.141 -9.782 5.939 1.00 37.85 N ANISOU 310 N CYS A 476 5091 4460 4830 -369 383 702 N ATOM 311 CA CYS A 476 32.512 -11.178 5.783 1.00 38.70 C ANISOU 311 CA CYS A 476 4984 4524 5196 -353 401 762 C ATOM 312 C CYS A 476 33.766 -11.480 6.643 1.00 52.01 C ANISOU 312 C CYS A 476 6654 6291 6817 -465 402 994 C ATOM 313 O CYS A 476 34.663 -10.692 6.679 1.00 42.13 O ANISOU 313 O CYS A 476 5527 5132 5347 -540 346 1051 O ATOM 314 CB CYS A 476 32.812 -11.353 4.304 1.00 35.80 C ANISOU 314 CB CYS A 476 4555 4159 4889 -256 333 597 C ATOM 315 SG CYS A 476 33.345 -12.990 3.889 1.00 38.64 S ANISOU 315 SG CYS A 476 4667 4446 5569 -188 314 587 S ATOM 316 N ALA A 477 33.789 -12.602 7.339 1.00 39.95 N ANISOU 316 N ALA A 477 4957 4726 5496 -480 457 1146 N ATOM 317 CA ALA A 477 34.935 -13.087 8.110 1.00 45.95 C ANISOU 317 CA ALA A 477 5655 5568 6235 -566 465 1384 C ATOM 318 C ALA A 477 35.867 -13.929 7.237 1.00 45.92 C ANISOU 318 C ALA A 477 5518 5525 6403 -517 418 1374 C ATOM 319 O ALA A 477 36.891 -14.429 7.687 1.00 47.66 O ANISOU 319 O ALA A 477 5663 5809 6636 -566 420 1566 O ATOM 320 CB ALA A 477 34.381 -13.926 9.267 1.00 43.56 C ANISOU 320 CB ALA A 477 5200 5253 6098 -582 556 1588 C ATOM 321 N GLY A 478 35.525 -14.093 5.962 1.00 44.45 N ANISOU 321 N GLY A 478 5292 5261 6334 -397 372 1138 N ATOM 322 CA GLY A 478 36.349 -14.878 5.056 1.00 44.92 C ANISOU 322 CA GLY A 478 5220 5318 6529 -298 320 1074 C ATOM 323 C GLY A 478 36.927 -14.048 3.946 1.00 52.07 C ANISOU 323 C GLY A 478 6211 6385 7188 -240 260 957 C ATOM 324 O GLY A 478 37.561 -13.029 4.231 1.00 53.41 O ANISOU 324 O GLY A 478 6518 6696 7080 -351 248 1093 O ATOM 325 N AARG A 479 36.765 -14.389 2.668 0.54 45.47 N ANISOU 325 N AARG A 479 5287 5559 6431 -66 209 721 N ATOM 326 N BARG A 479 36.661 -14.526 2.716 0.46 44.18 N ANISOU 326 N BARG A 479 5109 5367 6311 -62 211 712 N ATOM 327 CA AARG A 479 37.334 -13.475 1.671 0.54 45.26 C ANISOU 327 CA AARG A 479 5321 5755 6121 -12 167 682 C ATOM 328 CA BARG A 479 37.194 -14.013 1.465 0.46 43.78 C ANISOU 328 CA BARG A 479 5060 5520 6055 57 159 600 C ATOM 329 C AARG A 479 36.279 -13.032 0.645 0.54 43.40 C ANISOU 329 C AARG A 479 5108 5527 5856 114 138 423 C ATOM 330 C BARG A 479 36.027 -13.595 0.556 0.46 46.70 C ANISOU 330 C BARG A 479 5458 5874 6413 168 131 337 C ATOM 331 O AARG A 479 36.571 -12.860 -0.522 0.54 42.31 O ANISOU 331 O AARG A 479 4910 5572 5593 261 95 311 O ATOM 332 O BARG A 479 35.997 -13.942 -0.642 0.46 35.82 O ANISOU 332 O BARG A 479 3970 4593 5048 366 76 114 O ATOM 333 CB AARG A 479 38.554 -14.078 0.978 0.54 36.93 C ANISOU 333 CB AARG A 479 4122 4868 5043 113 134 705 C ATOM 334 CB BARG A 479 38.060 -15.097 0.789 0.46 47.21 C ANISOU 334 CB BARG A 479 5308 6018 6612 229 118 528 C ATOM 335 CG AARG A 479 39.507 -14.859 1.864 0.54 34.49 C ANISOU 335 CG AARG A 479 3735 4529 4842 42 159 923 C ATOM 336 CG BARG A 479 38.413 -14.877 -0.704 0.46 57.95 C ANISOU 336 CG BARG A 479 6598 7631 7790 443 63 346 C ATOM 337 CD AARG A 479 40.717 -15.245 0.955 0.54 45.74 C ANISOU 337 CD AARG A 479 5019 6185 6176 207 125 927 C ATOM 338 CD BARG A 479 39.727 -15.618 -1.127 0.46 63.77 C ANISOU 338 CD BARG A 479 7177 8544 8507 591 41 390 C ATOM 339 NE AARG A 479 41.541 -16.342 1.443 0.54 60.11 N ANISOU 339 NE AARG A 479 6703 7959 8177 241 136 1045 N ATOM 340 NE BARG A 479 39.756 -16.006 -2.546 0.46 59.14 N ANISOU 340 NE BARG A 479 6452 8148 7872 893 -24 94 N ATOM 341 CZ AARG A 479 42.200 -17.201 0.656 0.54 59.97 C ANISOU 341 CZ AARG A 479 6517 8032 8234 470 101 929 C ATOM 342 CZ BARG A 479 40.783 -16.612 -3.145 0.46 58.42 C ANISOU 342 CZ BARG A 479 6207 8268 7722 1098 -49 64 C ATOM 343 NH1AARG A 479 42.970 -18.145 1.189 0.54 46.98 N ANISOU 343 NH1AARG A 479 4756 6330 6765 495 112 1066 N ATOM 344 NH1BARG A 479 40.710 -16.926 -4.435 0.46 53.50 N ANISOU 344 NH1BARG A 479 5455 7854 7018 1405 -115 -242 N ATOM 345 NH2AARG A 479 42.086 -17.127 -0.671 0.54 58.27 N ANISOU 345 NH2AARG A 479 6241 7988 7911 700 52 670 N ATOM 346 NH2BARG A 479 41.887 -16.895 -2.463 0.46 56.95 N ANISOU 346 NH2BARG A 479 5986 8117 7536 1018 -11 335 N ATOM 347 N ASN A 480 35.058 -12.875 1.133 1.00 46.15 N ANISOU 347 N ASN A 480 5522 5707 6306 64 168 352 N ATOM 348 CA ASN A 480 33.852 -12.469 0.359 1.00 51.84 C ANISOU 348 CA ASN A 480 6263 6408 7026 165 149 122 C ATOM 349 C ASN A 480 33.458 -13.532 -0.645 1.00 54.63 C ANISOU 349 C ASN A 480 6429 6725 7603 361 84 -161 C ATOM 350 O ASN A 480 32.944 -13.257 -1.737 1.00 56.33 O ANISOU 350 O ASN A 480 6614 7047 7741 507 36 -375 O ATOM 351 CB ASN A 480 34.080 -11.103 -0.301 1.00 45.52 C ANISOU 351 CB ASN A 480 5587 5799 5910 168 129 162 C ATOM 352 CG ASN A 480 34.220 -9.974 0.730 1.00 55.04 C ANISOU 352 CG ASN A 480 6995 6968 6949 -25 155 375 C ATOM 353 OD1 ASN A 480 35.253 -9.314 0.822 1.00 65.57 O ANISOU 353 OD1 ASN A 480 8393 8412 8108 -118 126 563 O ATOM 354 ND2 ASN A 480 33.180 -9.747 1.499 1.00 58.35 N ANISOU 354 ND2 ASN A 480 7504 7241 7426 -75 198 339 N ATOM 355 N ASP A 481 33.658 -14.789 -0.282 1.00 43.37 N ANISOU 355 N ASP A 481 4864 5139 6477 377 66 -176 N ATOM 356 CA ASP A 481 33.212 -15.842 -1.183 1.00 39.21 C ANISOU 356 CA ASP A 481 4159 4519 6221 565 -33 -491 C ATOM 357 C ASP A 481 32.668 -17.076 -0.471 1.00 49.17 C ANISOU 357 C ASP A 481 5284 5454 7946 514 -57 -492 C ATOM 358 O ASP A 481 32.783 -18.222 -0.946 1.00 54.54 O ANISOU 358 O ASP A 481 5796 5994 8934 646 -161 -690 O ATOM 359 CB ASP A 481 34.344 -16.224 -2.106 1.00 50.08 C ANISOU 359 CB ASP A 481 5441 6093 7492 750 -94 -597 C ATOM 360 CG ASP A 481 35.396 -17.053 -1.412 1.00 64.33 C ANISOU 360 CG ASP A 481 7177 7817 9449 708 -78 -415 C ATOM 361 OD1 ASP A 481 35.685 -16.809 -0.196 1.00 51.51 O ANISOU 361 OD1 ASP A 481 5636 6125 7808 498 8 -97 O ATOM 362 OD2 ASP A 481 35.916 -17.956 -2.108 1.00 67.15 O ANISOU 362 OD2 ASP A 481 7388 8193 9934 909 -161 -610 O ATOM 363 N CYS A 482 32.035 -16.825 0.663 1.00 48.55 N ANISOU 363 N CYS A 482 5263 5258 7928 335 30 -270 N ATOM 364 CA CYS A 482 31.492 -17.882 1.476 1.00 44.47 C ANISOU 364 CA CYS A 482 4595 4464 7839 258 28 -165 C ATOM 365 C CYS A 482 30.546 -18.764 0.714 1.00 52.90 C ANISOU 365 C CYS A 482 5487 5317 9295 368 -103 -466 C ATOM 366 O CYS A 482 29.769 -18.308 -0.121 1.00 46.01 O ANISOU 366 O CYS A 482 4639 4513 8330 453 -152 -716 O ATOM 367 CB CYS A 482 30.820 -17.291 2.706 1.00 48.37 C ANISOU 367 CB CYS A 482 5169 4961 8248 88 152 111 C ATOM 368 SG CYS A 482 32.075 -16.326 3.766 1.00 39.04 S ANISOU 368 SG CYS A 482 4188 4017 6629 -50 267 449 S ATOM 369 N ILE A 483 30.597 -20.046 1.011 1.00 46.56 N ANISOU 369 N ILE A 483 4494 4240 8957 363 -174 -438 N ATOM 370 CA ILE A 483 29.576 -20.964 0.509 1.00 50.75 C ANISOU 370 CA ILE A 483 4832 4489 9961 420 -325 -686 C ATOM 371 C ILE A 483 28.246 -20.790 1.237 1.00 56.24 C ANISOU 371 C ILE A 483 5476 5081 10810 267 -264 -506 C ATOM 372 O ILE A 483 28.226 -20.834 2.453 1.00 55.71 O ANISOU 372 O ILE A 483 5385 4986 10794 115 -142 -121 O ATOM 373 CB ILE A 483 29.992 -22.384 0.774 1.00 52.97 C ANISOU 373 CB ILE A 483 4910 4450 10766 431 -428 -647 C ATOM 374 CG1 ILE A 483 31.237 -22.732 0.002 1.00 53.28 C ANISOU 374 CG1 ILE A 483 4961 4575 10710 625 -507 -862 C ATOM 375 CG2 ILE A 483 28.821 -23.334 0.431 1.00 67.70 C ANISOU 375 CG2 ILE A 483 6556 5959 13206 440 -606 -855 C ATOM 376 CD1 ILE A 483 31.967 -23.923 0.597 1.00 59.35 C ANISOU 376 CD1 ILE A 483 5576 5075 11898 614 -549 -688 C ATOM 377 N ILE A 484 27.128 -20.621 0.509 1.00 66.44 N ANISOU 377 N ILE A 484 6727 6349 12169 322 -347 -770 N ATOM 378 CA ILE A 484 25.831 -20.345 1.147 1.00 51.82 C ANISOU 378 CA ILE A 484 4821 4457 10413 196 -277 -591 C ATOM 379 C ILE A 484 24.820 -21.499 0.902 1.00 71.53 C ANISOU 379 C ILE A 484 7037 6610 13533 175 -452 -712 C ATOM 380 O ILE A 484 24.152 -21.500 -0.122 1.00 63.04 O ANISOU 380 O ILE A 484 5917 5516 12521 277 -593 -1073 O ATOM 381 CB ILE A 484 25.187 -19.038 0.616 1.00 47.16 C ANISOU 381 CB ILE A 484 4404 4136 9378 254 -217 -737 C ATOM 382 CG1 ILE A 484 26.039 -17.752 0.845 1.00 43.28 C ANISOU 382 CG1 ILE A 484 4188 3951 8305 255 -69 -611 C ATOM 383 CG2 ILE A 484 23.750 -18.864 1.183 1.00 50.21 C ANISOU 383 CG2 ILE A 484 4697 4479 9900 159 -161 -585 C ATOM 384 CD1 ILE A 484 26.431 -17.344 2.358 1.00 43.53 C ANISOU 384 CD1 ILE A 484 4316 4056 8168 100 107 -182 C ATOM 385 N ASP A 485 24.726 -22.496 1.793 1.00 58.75 N ANISOU 385 N ASP A 485 5211 4718 12394 46 -464 -410 N ATOM 386 CA ASP A 485 23.794 -23.599 1.606 1.00 64.97 C ANISOU 386 CA ASP A 485 5708 5138 13837 -2 -653 -481 C ATOM 387 C ASP A 485 22.765 -23.507 2.688 1.00 59.02 C ANISOU 387 C ASP A 485 4816 4391 13219 -177 -524 -43 C ATOM 388 O ASP A 485 22.652 -22.497 3.373 1.00 54.75 O ANISOU 388 O ASP A 485 4428 4166 12211 -213 -308 198 O ATOM 389 CB ASP A 485 24.482 -24.956 1.678 1.00 78.92 C ANISOU 389 CB ASP A 485 7293 6535 16158 -1 -807 -469 C ATOM 390 CG ASP A 485 25.234 -25.176 2.999 1.00 70.46 C ANISOU 390 CG ASP A 485 6197 5476 15097 -123 -633 61 C ATOM 391 OD1 ASP A 485 24.889 -24.529 4.019 1.00 67.20 O ANISOU 391 OD1 ASP A 485 5820 5290 14421 -244 -422 463 O ATOM 392 OD2 ASP A 485 26.176 -25.987 2.987 1.00 69.95 O ANISOU 392 OD2 ASP A 485 6075 5219 15284 -76 -714 54 O ATOM 393 N LYS A 486 22.037 -24.580 2.888 1.00 63.81 N ANISOU 393 N LYS A 486 5114 4652 14479 -279 -662 81 N ATOM 394 CA LYS A 486 20.809 -24.485 3.663 1.00 64.19 C ANISOU 394 CA LYS A 486 4976 4738 14673 -420 -569 449 C ATOM 395 C LYS A 486 21.132 -24.097 5.106 1.00 61.09 C ANISOU 395 C LYS A 486 4614 4598 13999 -508 -299 1008 C ATOM 396 O LYS A 486 20.420 -23.307 5.723 1.00 79.74 O ANISOU 396 O LYS A 486 7004 7252 16041 -534 -122 1237 O ATOM 397 CB LYS A 486 20.062 -25.823 3.612 1.00 70.56 C ANISOU 397 CB LYS A 486 5403 5088 16320 -535 -797 524 C ATOM 398 CG LYS A 486 18.781 -25.806 4.434 1.00 80.63 C ANISOU 398 CG LYS A 486 6428 6422 17787 -687 -702 973 C ATOM 399 CD LYS A 486 17.779 -26.865 3.958 1.00102.99 C ANISOU 399 CD LYS A 486 8903 8823 21403 -790 -985 895 C ATOM 400 CE LYS A 486 16.385 -26.663 4.586 1.00115.51 C ANISOU 400 CE LYS A 486 10243 10550 23097 -919 -888 1301 C ATOM 401 NZ LYS A 486 15.384 -27.691 4.151 1.00121.40 N ANISOU 401 NZ LYS A 486 10611 10867 24650 -1050 -1182 1264 N ATOM 402 N ILE A 487 22.211 -24.661 5.641 1.00 65.36 N ANISOU 402 N ILE A 487 5140 5047 14648 -533 -274 1214 N ATOM 403 CA ILE A 487 22.626 -24.385 7.006 1.00 73.51 C ANISOU 403 CA ILE A 487 6181 6335 15414 -603 -39 1731 C ATOM 404 C ILE A 487 23.670 -23.218 7.058 1.00 71.89 C ANISOU 404 C ILE A 487 6353 6493 14467 -510 109 1600 C ATOM 405 O ILE A 487 23.560 -22.278 7.863 1.00 71.88 O ANISOU 405 O ILE A 487 6482 6847 13982 -515 305 1814 O ATOM 406 CB ILE A 487 23.146 -25.706 7.654 1.00 96.49 C ANISOU 406 CB ILE A 487 8814 8943 18904 -697 -98 2102 C ATOM 407 CG1 ILE A 487 23.285 -25.559 9.168 1.00 98.91 C ANISOU 407 CG1 ILE A 487 9030 9543 19008 -777 140 2721 C ATOM 408 CG2 ILE A 487 24.443 -26.157 7.008 1.00101.21 C ANISOU 408 CG2 ILE A 487 9535 9350 19568 -606 -223 1806 C ATOM 409 CD1 ILE A 487 24.192 -24.414 9.609 1.00 86.77 C ANISOU 409 CD1 ILE A 487 7829 8440 16699 -704 331 2705 C ATOM 410 N ARG A 488 24.646 -23.224 6.167 1.00 58.06 N ANISOU 410 N ARG A 488 4773 4669 12619 -412 4 1233 N ATOM 411 CA ARG A 488 25.634 -22.122 6.161 1.00 51.76 C ANISOU 411 CA ARG A 488 4301 4197 11167 -345 122 1137 C ATOM 412 C ARG A 488 25.110 -20.731 5.753 1.00 57.64 C ANISOU 412 C ARG A 488 5291 5225 11384 -282 194 916 C ATOM 413 O ARG A 488 25.724 -19.706 6.103 1.00 51.26 O ANISOU 413 O ARG A 488 4725 4695 10055 -267 314 960 O ATOM 414 CB ARG A 488 26.810 -22.483 5.300 1.00 47.64 C ANISOU 414 CB ARG A 488 3865 3569 10669 -245 -1 845 C ATOM 415 CG ARG A 488 27.676 -23.601 5.995 1.00 52.13 C ANISOU 415 CG ARG A 488 4258 3944 11606 -298 -15 1150 C ATOM 416 CD ARG A 488 28.831 -23.873 5.190 1.00 60.28 C ANISOU 416 CD ARG A 488 5377 4922 12605 -172 -118 870 C ATOM 417 NE ARG A 488 28.454 -24.705 4.092 1.00 68.54 N ANISOU 417 NE ARG A 488 6289 5648 14105 -67 -344 477 N ATOM 418 CZ ARG A 488 29.295 -25.556 3.526 1.00 81.86 C ANISOU 418 CZ ARG A 488 7913 7135 16056 55 -489 275 C ATOM 419 NH1 ARG A 488 30.547 -25.636 3.997 1.00 67.20 N ANISOU 419 NH1 ARG A 488 6112 5385 14034 69 -404 482 N ATOM 420 NH2 ARG A 488 28.883 -26.337 2.515 1.00 81.27 N ANISOU 420 NH2 ARG A 488 7709 6758 16412 173 -727 -138 N ATOM 421 N ARG A 489 23.996 -20.667 5.019 1.00 47.96 N ANISOU 421 N ARG A 489 3999 3921 10303 -245 108 680 N ATOM 422 CA ARG A 489 23.501 -19.361 4.584 1.00 38.34 C ANISOU 422 CA ARG A 489 3001 2956 8608 -170 171 480 C ATOM 423 C ARG A 489 23.341 -18.441 5.789 1.00 46.51 C ANISOU 423 C ARG A 489 4155 4275 9242 -213 378 799 C ATOM 424 O ARG A 489 23.367 -17.216 5.642 1.00 50.02 O ANISOU 424 O ARG A 489 4849 4942 9216 -150 446 674 O ATOM 425 CB ARG A 489 22.098 -19.511 3.866 1.00 47.00 C ANISOU 425 CB ARG A 489 3947 3947 9964 -142 68 277 C ATOM 426 CG ARG A 489 21.107 -20.230 4.680 1.00 53.28 C ANISOU 426 CG ARG A 489 4451 4619 11174 -256 91 609 C ATOM 427 CD ARG A 489 19.828 -20.475 3.899 1.00 61.86 C ANISOU 427 CD ARG A 489 5363 5576 12563 -242 -46 397 C ATOM 428 NE ARG A 489 18.779 -20.877 4.800 1.00 64.50 N ANISOU 428 NE ARG A 489 5426 5888 13194 -354 20 793 N ATOM 429 CZ ARG A 489 17.759 -21.649 4.462 1.00 67.08 C ANISOU 429 CZ ARG A 489 5459 5984 14044 -418 -131 779 C ATOM 430 NH1 ARG A 489 17.612 -22.114 3.202 1.00 56.84 N ANISOU 430 NH1 ARG A 489 4115 4448 13032 -371 -378 327 N ATOM 431 NH2 ARG A 489 16.895 -21.961 5.407 1.00 61.28 N ANISOU 431 NH2 ARG A 489 4460 5283 13543 -525 -42 1229 N ATOM 432 N LYS A 490 23.253 -19.021 6.996 1.00 44.72 N ANISOU 432 N LYS A 490 3746 4051 9193 -306 471 1216 N ATOM 433 CA LYS A 490 23.152 -18.213 8.233 1.00 42.50 C ANISOU 433 CA LYS A 490 3557 4089 8502 -314 662 1513 C ATOM 434 C LYS A 490 24.487 -17.564 8.689 1.00 61.70 C ANISOU 434 C LYS A 490 6240 6705 10500 -312 723 1543 C ATOM 435 O LYS A 490 24.529 -16.595 9.468 1.00 63.54 O ANISOU 435 O LYS A 490 6638 7213 10291 -285 839 1637 O ATOM 436 CB LYS A 490 22.683 -19.152 9.339 1.00 68.83 C ANISOU 436 CB LYS A 490 6566 7409 12176 -399 734 1981 C ATOM 437 CG LYS A 490 21.756 -18.532 10.344 1.00 78.26 C ANISOU 437 CG LYS A 490 7712 8923 13100 -364 903 2247 C ATOM 438 CD LYS A 490 20.836 -19.584 10.958 1.00 80.92 C ANISOU 438 CD LYS A 490 7634 9192 13919 -440 929 2664 C ATOM 439 CE LYS A 490 20.460 -19.209 12.391 1.00 89.18 C ANISOU 439 CE LYS A 490 8585 10657 14644 -396 1138 3094 C ATOM 440 NZ LYS A 490 19.377 -20.090 12.988 1.00 94.68 N ANISOU 440 NZ LYS A 490 8840 11363 15769 -455 1185 3557 N ATOM 441 N ASN A 491 25.595 -18.132 8.246 1.00 45.36 N ANISOU 441 N ASN A 491 4182 4483 8569 -335 633 1467 N ATOM 442 CA ASN A 491 26.914 -17.671 8.702 1.00 44.18 C ANISOU 442 CA ASN A 491 4220 4497 8071 -354 677 1543 C ATOM 443 C ASN A 491 27.273 -16.321 8.206 1.00 47.38 C ANISOU 443 C ASN A 491 4939 5065 8000 -302 672 1283 C ATOM 444 O ASN A 491 27.933 -15.566 8.917 1.00 50.83 O ANISOU 444 O ASN A 491 5545 5703 8065 -328 732 1387 O ATOM 445 CB ASN A 491 28.023 -18.570 8.215 1.00 50.09 C ANISOU 445 CB ASN A 491 4900 5058 9073 -367 577 1503 C ATOM 446 CG ASN A 491 27.988 -19.941 8.833 1.00 58.13 C ANISOU 446 CG ASN A 491 5613 5888 10587 -431 571 1816 C ATOM 447 OD1 ASN A 491 28.955 -20.675 8.724 1.00 54.55 O ANISOU 447 OD1 ASN A 491 5096 5306 10325 -436 513 1859 O ATOM 448 ND2 ASN A 491 26.874 -20.313 9.449 1.00 53.39 N ANISOU 448 ND2 ASN A 491 4801 5263 10222 -473 625 2054 N ATOM 449 N CYS A 492 26.931 -16.009 6.958 1.00 42.74 N ANISOU 449 N CYS A 492 4424 4391 7426 -228 582 949 N ATOM 450 CA CYS A 492 27.501 -14.817 6.377 1.00 32.97 C ANISOU 450 CA CYS A 492 3457 3286 5785 -186 559 748 C ATOM 451 C CYS A 492 26.540 -14.033 5.581 1.00 40.67 C ANISOU 451 C CYS A 492 4519 4283 6649 -101 537 505 C ATOM 452 O CYS A 492 26.423 -14.216 4.358 1.00 41.63 O ANISOU 452 O CYS A 492 4606 4326 6885 -26 439 252 O ATOM 453 CB CYS A 492 28.770 -15.137 5.535 1.00 34.51 C ANISOU 453 CB CYS A 492 3677 3436 5998 -169 464 627 C ATOM 454 SG CYS A 492 29.634 -13.631 4.937 1.00 37.68 S ANISOU 454 SG CYS A 492 4373 4033 5909 -149 438 496 S ATOM 455 N PRO A 493 25.823 -13.128 6.268 1.00 44.38 N ANISOU 455 N PRO A 493 5098 4886 6876 -87 626 572 N ATOM 456 CA PRO A 493 24.890 -12.267 5.570 1.00 38.36 C ANISOU 456 CA PRO A 493 4432 4157 5986 7 614 362 C ATOM 457 C PRO A 493 25.559 -11.360 4.551 1.00 42.81 C ANISOU 457 C PRO A 493 5195 4759 6310 51 538 158 C ATOM 458 O PRO A 493 24.907 -11.077 3.536 1.00 34.75 O ANISOU 458 O PRO A 493 4170 3730 5306 141 490 -44 O ATOM 459 CB PRO A 493 24.218 -11.450 6.681 1.00 38.11 C ANISOU 459 CB PRO A 493 4494 4279 5706 32 727 492 C ATOM 460 CG PRO A 493 24.870 -11.822 7.914 1.00 47.88 C ANISOU 460 CG PRO A 493 5695 5599 6897 -45 790 753 C ATOM 461 CD PRO A 493 25.812 -12.941 7.721 1.00 50.24 C ANISOU 461 CD PRO A 493 5854 5773 7461 -131 737 840 C ATOM 462 N ALA A 494 26.847 -10.992 4.685 1.00 37.39 N ANISOU 462 N ALA A 494 4645 4127 5435 -9 514 222 N ATOM 463 CA ALA A 494 27.405 -10.211 3.596 1.00 31.09 C ANISOU 463 CA ALA A 494 3977 3377 4458 35 437 73 C ATOM 464 C ALA A 494 27.391 -11.007 2.306 1.00 31.46 C ANISOU 464 C ALA A 494 3861 3386 4708 123 358 -113 C ATOM 465 O ALA A 494 27.100 -10.474 1.222 1.00 37.34 O ANISOU 465 O ALA A 494 4634 4196 5357 222 308 -284 O ATOM 466 CB ALA A 494 28.951 -9.810 3.933 1.00 37.45 C ANISOU 466 CB ALA A 494 4911 4253 5065 -65 408 215 C ATOM 467 N CYS A 495 27.897 -12.222 2.357 1.00 31.96 N ANISOU 467 N CYS A 495 3759 3365 5019 101 330 -83 N ATOM 468 CA CYS A 495 28.012 -13.042 1.143 1.00 30.87 C ANISOU 468 CA CYS A 495 3465 3192 5072 213 227 -308 C ATOM 469 C CYS A 495 26.546 -13.479 0.713 1.00 44.14 C ANISOU 469 C CYS A 495 5001 4767 7004 283 189 -493 C ATOM 470 O CYS A 495 26.221 -13.672 -0.455 1.00 37.78 O ANISOU 470 O CYS A 495 4113 3988 6254 410 93 -754 O ATOM 471 CB CYS A 495 28.840 -14.266 1.439 1.00 37.18 C ANISOU 471 CB CYS A 495 4121 3883 6124 182 197 -232 C ATOM 472 SG CYS A 495 30.711 -13.820 1.342 1.00 38.80 S ANISOU 472 SG CYS A 495 4447 4275 6021 158 195 -98 S ATOM 473 N ARG A 496 25.664 -13.707 1.657 1.00 30.32 N ANISOU 473 N ARG A 496 3188 2919 5413 207 257 -349 N ATOM 474 CA ARG A 496 24.273 -14.092 1.275 1.00 30.84 C ANISOU 474 CA ARG A 496 3094 2895 5728 256 215 -488 C ATOM 475 C ARG A 496 23.610 -12.965 0.472 1.00 30.20 C ANISOU 475 C ARG A 496 3134 2967 5373 361 213 -661 C ATOM 476 O ARG A 496 23.013 -13.162 -0.610 1.00 38.85 O ANISOU 476 O ARG A 496 4127 4071 6563 467 114 -913 O ATOM 477 CB ARG A 496 23.448 -14.379 2.515 1.00 35.36 C ANISOU 477 CB ARG A 496 3568 3400 6466 159 313 -231 C ATOM 478 CG ARG A 496 22.048 -15.127 2.110 1.00 38.44 C ANISOU 478 CG ARG A 496 3707 3652 7248 180 237 -338 C ATOM 479 CD ARG A 496 21.153 -15.323 3.327 1.00 41.60 C ANISOU 479 CD ARG A 496 3976 4047 7785 97 350 -27 C ATOM 480 NE ARG A 496 19.978 -16.201 3.079 1.00 42.35 N ANISOU 480 NE ARG A 496 3782 3981 8327 74 265 -49 N ATOM 481 CZ ARG A 496 19.176 -16.616 4.056 1.00 52.63 C ANISOU 481 CZ ARG A 496 4885 5270 9841 -5 345 266 C ATOM 482 NH1 ARG A 496 19.468 -16.214 5.301 1.00 42.41 N ANISOU 482 NH1 ARG A 496 3667 4147 8301 -38 515 585 N ATOM 483 NH2 ARG A 496 18.088 -17.408 3.802 1.00 43.78 N ANISOU 483 NH2 ARG A 496 3474 3991 9167 -46 249 271 N ATOM 484 N TYR A 497 23.777 -11.759 0.945 1.00 32.81 N ANISOU 484 N TYR A 497 3681 3422 5362 343 305 -538 N ATOM 485 CA TYR A 497 23.181 -10.607 0.269 1.00 29.64 C ANISOU 485 CA TYR A 497 3402 3145 4716 443 307 -656 C ATOM 486 C TYR A 497 23.874 -10.378 -1.063 1.00 45.29 C ANISOU 486 C TYR A 497 5403 5243 6564 540 214 -828 C ATOM 487 O TYR A 497 23.238 -10.089 -2.046 1.00 35.86 O ANISOU 487 O TYR A 497 4164 4139 5323 659 164 -1002 O ATOM 488 CB TYR A 497 23.253 -9.382 1.177 1.00 38.06 C ANISOU 488 CB TYR A 497 4699 4272 5490 404 405 -489 C ATOM 489 CG TYR A 497 22.715 -8.156 0.494 1.00 45.02 C ANISOU 489 CG TYR A 497 5710 5245 6150 510 398 -588 C ATOM 490 CD1 TYR A 497 21.330 -8.034 0.234 1.00 35.48 C ANISOU 490 CD1 TYR A 497 4421 4056 5006 604 417 -680 C ATOM 491 CD2 TYR A 497 23.557 -7.135 0.077 1.00 41.75 C ANISOU 491 CD2 TYR A 497 5476 4899 5491 516 365 -563 C ATOM 492 CE1 TYR A 497 20.827 -6.919 -0.362 1.00 33.88 C ANISOU 492 CE1 TYR A 497 4327 3934 4612 711 415 -748 C ATOM 493 CE2 TYR A 497 23.037 -5.972 -0.571 1.00 45.31 C ANISOU 493 CE2 TYR A 497 6030 5414 5771 617 352 -617 C ATOM 494 CZ TYR A 497 21.645 -5.881 -0.767 1.00 51.57 C ANISOU 494 CZ TYR A 497 6751 6222 6621 722 383 -715 C ATOM 495 OH TYR A 497 21.065 -4.796 -1.393 1.00 44.42 O ANISOU 495 OH TYR A 497 5928 5380 5570 836 375 -755 O ATOM 496 N ARG A 498 25.191 -10.551 -1.162 1.00 35.74 N ANISOU 496 N ARG A 498 4229 4070 5281 509 187 -773 N ATOM 497 CA ARG A 498 25.781 -10.496 -2.501 1.00 28.11 C ANISOU 497 CA ARG A 498 3217 3268 4194 639 100 -932 C ATOM 498 C ARG A 498 25.248 -11.547 -3.456 1.00 37.91 C ANISOU 498 C ARG A 498 4236 4499 5667 772 -11 -1223 C ATOM 499 O ARG A 498 25.096 -11.277 -4.617 1.00 38.76 O ANISOU 499 O ARG A 498 4296 4793 5640 925 -77 -1403 O ATOM 500 CB ARG A 498 27.370 -10.650 -2.388 1.00 36.10 C ANISOU 500 CB ARG A 498 4267 4342 5106 588 93 -798 C ATOM 501 CG ARG A 498 28.014 -11.133 -3.728 1.00 51.80 C ANISOU 501 CG ARG A 498 6116 6517 7049 761 -4 -987 C ATOM 502 CD ARG A 498 29.607 -11.395 -3.550 1.00 61.60 C ANISOU 502 CD ARG A 498 7364 7835 8207 721 -2 -828 C ATOM 503 NE ARG A 498 29.897 -12.491 -2.618 1.00 65.37 N ANISOU 503 NE ARG A 498 7779 8096 8964 625 8 -773 N ATOM 504 CZ ARG A 498 29.747 -13.789 -2.906 1.00 71.82 C ANISOU 504 CZ ARG A 498 8413 8789 10086 715 -71 -975 C ATOM 505 NH1 ARG A 498 29.317 -14.176 -4.104 1.00 69.74 N ANISOU 505 NH1 ARG A 498 8018 8611 9867 912 -177 -1294 N ATOM 506 NH2 ARG A 498 30.029 -14.712 -1.996 1.00 72.66 N ANISOU 506 NH2 ARG A 498 8458 8683 10468 615 -58 -863 N ATOM 507 N LYS A 499 25.043 -12.789 -3.041 1.00 37.88 N ANISOU 507 N LYS A 499 4080 4290 6023 726 -55 -1279 N ATOM 508 CA LYS A 499 24.452 -13.764 -3.950 1.00 40.36 C ANISOU 508 CA LYS A 499 4182 4551 6602 850 -201 -1596 C ATOM 509 C LYS A 499 22.984 -13.402 -4.361 1.00 35.68 C ANISOU 509 C LYS A 499 3533 3986 6039 902 -225 -1730 C ATOM 510 O LYS A 499 22.550 -13.736 -5.489 1.00 44.05 O ANISOU 510 O LYS A 499 4456 5134 7147 1055 -359 -2038 O ATOM 511 CB LYS A 499 24.374 -15.096 -3.260 1.00 44.53 C ANISOU 511 CB LYS A 499 4552 4783 7584 756 -251 -1575 C ATOM 512 CG LYS A 499 25.712 -15.783 -3.164 1.00 52.01 C ANISOU 512 CG LYS A 499 5481 5689 8590 763 -280 -1543 C ATOM 513 CD LYS A 499 25.513 -17.253 -2.981 1.00 59.05 C ANISOU 513 CD LYS A 499 6159 6275 10003 743 -402 -1645 C ATOM 514 CE LYS A 499 24.625 -17.770 -4.131 1.00 66.19 C ANISOU 514 CE LYS A 499 6896 7143 11112 894 -591 -2056 C ATOM 515 NZ LYS A 499 24.983 -19.155 -4.460 1.00 61.92 N ANISOU 515 NZ LYS A 499 6169 6364 10993 971 -775 -2291 N ATOM 516 N CYS A 500 22.213 -12.762 -3.457 1.00 46.43 N ANISOU 516 N CYS A 500 4981 5294 7365 793 -104 -1516 N ATOM 517 CA CYS A 500 20.842 -12.313 -3.829 1.00 41.74 C ANISOU 517 CA CYS A 500 4336 4759 6763 854 -110 -1611 C ATOM 518 C CYS A 500 20.979 -11.328 -4.957 1.00 50.32 C ANISOU 518 C CYS A 500 5510 6116 7494 1011 -130 -1732 C ATOM 519 O CYS A 500 20.307 -11.448 -5.972 1.00 42.02 O ANISOU 519 O CYS A 500 4329 5178 6458 1144 -231 -1973 O ATOM 520 CB CYS A 500 20.171 -11.547 -2.708 1.00 41.72 C ANISOU 520 CB CYS A 500 4449 4729 6675 761 43 -1350 C ATOM 521 SG CYS A 500 19.666 -12.578 -1.376 1.00 43.53 S ANISOU 521 SG CYS A 500 4521 4727 7293 602 90 -1142 S ATOM 522 N LEU A 501 21.845 -10.323 -4.774 1.00 39.52 N ANISOU 522 N LEU A 501 4346 4861 5810 993 -42 -1545 N ATOM 523 CA LEU A 501 22.080 -9.351 -5.864 1.00 45.25 C ANISOU 523 CA LEU A 501 5128 5854 6210 1135 -60 -1588 C ATOM 524 C LEU A 501 22.578 -10.021 -7.114 1.00 49.34 C ANISOU 524 C LEU A 501 5481 6559 6705 1299 -189 -1838 C ATOM 525 O LEU A 501 22.154 -9.685 -8.205 1.00 52.59 O ANISOU 525 O LEU A 501 5812 7207 6962 1466 -247 -1988 O ATOM 526 CB LEU A 501 23.086 -8.247 -5.438 1.00 48.08 C ANISOU 526 CB LEU A 501 5708 6263 6299 1061 25 -1315 C ATOM 527 CG LEU A 501 22.627 -7.292 -4.335 1.00 49.30 C ANISOU 527 CG LEU A 501 6057 6283 6393 953 132 -1112 C ATOM 528 CD1 LEU A 501 23.747 -6.377 -4.025 1.00 47.34 C ANISOU 528 CD1 LEU A 501 5995 6054 5937 875 159 -897 C ATOM 529 CD2 LEU A 501 21.337 -6.431 -4.676 1.00 38.10 C ANISOU 529 CD2 LEU A 501 4658 4922 4894 1056 157 -1153 C ATOM 530 N GLN A 502 23.481 -10.984 -6.986 1.00 43.84 N ANISOU 530 N GLN A 502 4722 5786 6150 1278 -239 -1892 N ATOM 531 CA GLN A 502 24.033 -11.613 -8.185 1.00 50.27 C ANISOU 531 CA GLN A 502 5379 6812 6908 1478 -367 -2159 C ATOM 532 C GLN A 502 23.010 -12.437 -8.902 1.00 48.54 C ANISOU 532 C GLN A 502 4959 6574 6911 1604 -519 -2527 C ATOM 533 O GLN A 502 23.089 -12.637 -10.106 1.00 54.09 O ANISOU 533 O GLN A 502 5531 7544 7478 1827 -635 -2800 O ATOM 534 CB GLN A 502 25.217 -12.572 -7.832 1.00 58.37 C ANISOU 534 CB GLN A 502 6371 7728 8078 1446 -397 -2157 C ATOM 535 CG GLN A 502 26.421 -11.937 -7.206 1.00 72.87 C ANISOU 535 CG GLN A 502 8370 9610 9708 1330 -281 -1821 C ATOM 536 CD GLN A 502 27.591 -12.942 -7.034 1.00 78.53 C ANISOU 536 CD GLN A 502 9017 10270 10550 1342 -321 -1843 C ATOM 537 OE1 GLN A 502 28.737 -12.625 -7.335 1.00 83.72 O ANISOU 537 OE1 GLN A 502 9699 11148 10963 1394 -295 -1717 O ATOM 538 NE2 GLN A 502 27.289 -14.150 -6.553 1.00 61.60 N ANISOU 538 NE2 GLN A 502 6770 7830 8806 1296 -387 -1978 N ATOM 539 N ALA A 503 22.032 -12.962 -8.165 1.00 56.03 N ANISOU 539 N ALA A 503 5857 7220 8211 1468 -532 -2539 N ATOM 540 CA ALA A 503 20.979 -13.753 -8.791 1.00 52.01 C ANISOU 540 CA ALA A 503 5137 6652 7971 1554 -702 -2877 C ATOM 541 C ALA A 503 19.918 -12.848 -9.437 1.00 54.00 C ANISOU 541 C ALA A 503 5378 7133 8005 1648 -690 -2923 C ATOM 542 O ALA A 503 19.043 -13.307 -10.195 1.00 52.95 O ANISOU 542 O ALA A 503 5064 7051 8002 1756 -845 -3227 O ATOM 543 CB ALA A 503 20.327 -14.676 -7.768 1.00 54.86 C ANISOU 543 CB ALA A 503 5406 6611 8827 1360 -728 -2815 C ATOM 544 N GLY A 504 19.985 -11.561 -9.163 1.00 44.08 N ANISOU 544 N GLY A 504 4306 6011 6431 1614 -525 -2633 N ATOM 545 CA GLY A 504 19.070 -10.624 -9.813 1.00 49.23 C ANISOU 545 CA GLY A 504 4952 6894 6861 1724 -506 -2645 C ATOM 546 C GLY A 504 17.936 -10.119 -8.943 1.00 55.64 C ANISOU 546 C GLY A 504 5825 7539 7778 1598 -401 -2460 C ATOM 547 O GLY A 504 17.082 -9.347 -9.413 1.00 53.10 O ANISOU 547 O GLY A 504 5493 7386 7299 1691 -381 -2458 O ATOM 548 N MET A 505 17.892 -10.499 -7.662 1.00 40.87 N ANISOU 548 N MET A 505 4007 5372 6149 1406 -324 -2282 N ATOM 549 CA MET A 505 16.798 -9.946 -6.821 1.00 38.68 C ANISOU 549 CA MET A 505 3776 5004 5917 1327 -208 -2092 C ATOM 550 C MET A 505 16.675 -8.414 -6.855 1.00 53.46 C ANISOU 550 C MET A 505 5847 7039 7427 1397 -84 -1914 C ATOM 551 O MET A 505 17.684 -7.686 -6.798 1.00 46.15 O ANISOU 551 O MET A 505 5104 6167 6265 1392 -26 -1772 O ATOM 552 CB MET A 505 16.949 -10.466 -5.376 1.00 41.33 C ANISOU 552 CB MET A 505 4144 5072 6486 1135 -120 -1872 C ATOM 553 CG MET A 505 16.968 -12.005 -5.362 1.00 45.46 C ANISOU 553 CG MET A 505 4440 5390 7441 1063 -260 -2019 C ATOM 554 SD MET A 505 16.866 -12.743 -3.715 1.00 46.72 S ANISOU 554 SD MET A 505 4547 5266 7938 846 -164 -1709 S ATOM 555 CE MET A 505 15.147 -12.479 -3.223 1.00 40.85 C ANISOU 555 CE MET A 505 3672 4541 7309 823 -96 -1576 C ATOM 556 N ASN A 506 15.432 -7.915 -6.902 1.00 45.72 N ANISOU 556 N ASN A 506 4823 6116 6433 1456 -51 -1904 N ATOM 557 CA ASN A 506 15.149 -6.477 -6.844 1.00 42.02 C ANISOU 557 CA ASN A 506 4533 5750 5682 1533 60 -1736 C ATOM 558 C ASN A 506 13.689 -6.235 -6.367 1.00 43.91 C ANISOU 558 C ASN A 506 4708 5969 6007 1559 125 -1685 C ATOM 559 O ASN A 506 12.798 -6.976 -6.714 1.00 46.75 O ANISOU 559 O ASN A 506 4840 6353 6569 1574 45 -1828 O ATOM 560 CB ASN A 506 15.363 -5.851 -8.226 1.00 48.55 C ANISOU 560 CB ASN A 506 5337 6853 6257 1705 -7 -1823 C ATOM 561 CG ASN A 506 14.422 -6.415 -9.287 1.00 55.00 C ANISOU 561 CG ASN A 506 5897 7853 7148 1834 -134 -2083 C ATOM 562 OD1 ASN A 506 14.615 -7.505 -9.803 1.00 62.18 O ANISOU 562 OD1 ASN A 506 6633 8781 8211 1844 -271 -2324 O ATOM 563 ND2 ASN A 506 13.421 -5.643 -9.636 1.00 50.44 N ANISOU 563 ND2 ASN A 506 5294 7412 6458 1946 -102 -2047 N ATOM 564 N LEU A 507 13.502 -5.249 -5.534 1.00 40.45 N ANISOU 564 N LEU A 507 4461 5480 5429 1564 258 -1489 N ATOM 565 CA LEU A 507 12.253 -5.058 -4.826 1.00 52.19 C ANISOU 565 CA LEU A 507 5897 6952 6980 1594 347 -1406 C ATOM 566 C LEU A 507 11.128 -4.819 -5.824 1.00 74.14 C ANISOU 566 C LEU A 507 8515 9918 9738 1743 295 -1518 C ATOM 567 O LEU A 507 10.018 -5.320 -5.650 1.00 78.12 O ANISOU 567 O LEU A 507 8820 10443 10419 1743 293 -1535 O ATOM 568 CB LEU A 507 12.375 -3.873 -3.890 1.00 64.76 C ANISOU 568 CB LEU A 507 7753 8487 8366 1631 480 -1227 C ATOM 569 CG LEU A 507 11.985 -4.182 -2.457 1.00 78.58 C ANISOU 569 CG LEU A 507 9500 10151 10204 1566 591 -1090 C ATOM 570 CD1 LEU A 507 12.499 -5.563 -2.071 1.00 77.41 C ANISOU 570 CD1 LEU A 507 9202 9899 10312 1388 548 -1081 C ATOM 571 CD2 LEU A 507 12.512 -3.099 -1.520 1.00 78.69 C ANISOU 571 CD2 LEU A 507 9809 10097 9993 1597 680 -975 C ATOM 572 N GLU A 508 11.441 -4.095 -6.891 1.00 65.18 N ANISOU 572 N GLU A 508 7436 8938 8390 1865 247 -1573 N ATOM 573 CA GLU A 508 10.431 -3.626 -7.810 1.00 69.61 C ANISOU 573 CA GLU A 508 7873 9711 8866 2031 215 -1637 C ATOM 574 C GLU A 508 10.264 -4.555 -8.978 1.00 67.68 C ANISOU 574 C GLU A 508 7369 9633 8715 2067 48 -1889 C ATOM 575 O GLU A 508 9.840 -4.128 -10.046 1.00 72.52 O ANISOU 575 O GLU A 508 7886 10492 9176 2225 -10 -1965 O ATOM 576 CB GLU A 508 10.804 -2.236 -8.292 1.00 77.92 C ANISOU 576 CB GLU A 508 9113 10857 9638 2161 258 -1510 C ATOM 577 CG GLU A 508 10.675 -1.197 -7.181 1.00 98.56 C ANISOU 577 CG GLU A 508 11972 13297 12179 2171 393 -1315 C ATOM 578 CD GLU A 508 9.305 -1.215 -6.505 1.00110.45 C ANISOU 578 CD GLU A 508 13392 14805 13770 2232 476 -1293 C ATOM 579 OE1 GLU A 508 8.277 -1.170 -7.223 1.00118.60 O ANISOU 579 OE1 GLU A 508 14242 16017 14802 2354 449 -1349 O ATOM 580 OE2 GLU A 508 9.256 -1.264 -5.254 1.00108.34 O ANISOU 580 OE2 GLU A 508 13221 14391 13551 2170 570 -1208 O ATOM 581 N ALA A 509 10.577 -5.833 -8.788 1.00 53.28 N ANISOU 581 N ALA A 509 5418 7680 7147 1936 -45 -2029 N ATOM 582 CA ALA A 509 10.503 -6.757 -9.907 1.00 60.09 C ANISOU 582 CA ALA A 509 6041 8677 8113 1988 -241 -2330 C ATOM 583 C ALA A 509 9.052 -6.857 -10.395 1.00 67.59 C ANISOU 583 C ALA A 509 6759 9767 9154 2069 -312 -2437 C ATOM 584 O ALA A 509 8.824 -6.917 -11.587 1.00 66.95 O ANISOU 584 O ALA A 509 6530 9939 8969 2211 -445 -2651 O ATOM 585 CB ALA A 509 11.013 -8.119 -9.527 1.00 61.16 C ANISOU 585 CB ALA A 509 6079 8587 8573 1835 -342 -2461 C ATOM 586 N ARG A 510 8.098 -6.901 -9.469 1.00 66.00 N ANISOU 586 N ARG A 510 6508 9434 9134 1986 -226 -2282 N ATOM 587 CA ARG A 510 6.653 -6.997 -9.819 1.00 87.78 C ANISOU 587 CA ARG A 510 9025 12326 12003 2046 -285 -2338 C ATOM 588 C ARG A 510 6.258 -5.852 -10.751 1.00 95.99 C ANISOU 588 C ARG A 510 10099 13674 12697 2267 -257 -2334 C ATOM 589 O ARG A 510 5.825 -6.061 -11.889 1.00 96.40 O ANISOU 589 O ARG A 510 9954 13963 12709 2379 -411 -2553 O ATOM 590 CB ARG A 510 5.787 -6.913 -8.550 1.00 92.24 C ANISOU 590 CB ARG A 510 9568 12759 12722 1959 -134 -2073 C ATOM 591 CG ARG A 510 4.669 -7.940 -8.442 1.00106.81 C ANISOU 591 CG ARG A 510 11075 14557 14952 1856 -250 -2118 C ATOM 592 CD ARG A 510 3.620 -7.529 -7.380 1.00110.86 C ANISOU 592 CD ARG A 510 11540 15086 15496 1854 -70 -1808 C ATOM 593 NE ARG A 510 2.899 -8.682 -6.826 1.00110.74 N ANISOU 593 NE ARG A 510 11215 14938 15922 1676 -145 -1726 N ATOM 594 CZ ARG A 510 2.116 -8.645 -5.744 1.00 98.66 C ANISOU 594 CZ ARG A 510 9583 13416 14486 1638 5 -1416 C ATOM 595 NH1 ARG A 510 1.940 -7.505 -5.084 1.00 98.94 N ANISOU 595 NH1 ARG A 510 9824 13583 14186 1789 235 -1211 N ATOM 596 NH2 ARG A 510 1.511 -9.755 -5.312 1.00 79.47 N ANISOU 596 NH2 ARG A 510 6832 10867 12497 1459 -83 -1303 N ATOM 597 N LYS A 511 6.412 -4.636 -10.232 1.00 98.54 N ANISOU 597 N LYS A 511 10669 13988 12784 2334 -69 -2081 N ATOM 598 CA LYS A 511 6.170 -3.407 -10.976 1.00104.12 C ANISOU 598 CA LYS A 511 11446 14932 13182 2539 -21 -2000 C ATOM 599 C LYS A 511 6.961 -3.351 -12.285 1.00 98.25 C ANISOU 599 C LYS A 511 10668 14428 12234 2646 -141 -2146 C ATOM 600 O LYS A 511 6.557 -2.695 -13.244 1.00100.57 O ANISOU 600 O LYS A 511 10883 15012 12318 2830 -166 -2140 O ATOM 601 CB LYS A 511 6.545 -2.214 -10.092 1.00113.20 C ANISOU 601 CB LYS A 511 12906 15931 14174 2563 166 -1729 C ATOM 602 CG LYS A 511 6.905 -0.952 -10.849 1.00120.59 C ANISOU 602 CG LYS A 511 13976 17018 14825 2731 194 -1611 C ATOM 603 CD LYS A 511 7.402 0.110 -9.897 1.00124.00 C ANISOU 603 CD LYS A 511 14721 17218 15175 2722 331 -1386 C ATOM 604 CE LYS A 511 6.833 1.472 -10.248 1.00128.05 C ANISOU 604 CE LYS A 511 15310 17820 15525 2925 392 -1222 C ATOM 605 NZ LYS A 511 6.561 2.267 -9.019 1.00127.48 N ANISOU 605 NZ LYS A 511 15464 17506 15466 2953 522 -1087 N ATOM 606 N THR A 512 8.093 -4.046 -12.325 1.00 85.40 N ANISOU 606 N THR A 512 9081 12712 10655 2550 -210 -2260 N ATOM 607 CA THR A 512 8.959 -4.008 -13.494 1.00 79.85 C ANISOU 607 CA THR A 512 8339 12274 9727 2671 -308 -2377 C ATOM 608 C THR A 512 8.647 -5.106 -14.516 1.00 81.84 C ANISOU 608 C THR A 512 8298 12740 10057 2744 -529 -2754 C ATOM 609 O THR A 512 8.926 -4.933 -15.703 1.00 85.71 O ANISOU 609 O THR A 512 8683 13593 10292 2931 -617 -2870 O ATOM 610 CB THR A 512 10.456 -4.095 -13.078 1.00 90.22 C ANISOU 610 CB THR A 512 9848 13426 11006 2565 -267 -2295 C ATOM 611 OG1 THR A 512 10.923 -2.789 -12.704 1.00 95.36 O ANISOU 611 OG1 THR A 512 10744 14022 11467 2578 -118 -1973 O ATOM 612 CG2 THR A 512 11.312 -4.635 -14.211 1.00 78.51 C ANISOU 612 CG2 THR A 512 8237 12213 9379 2673 -408 -2508 C ATOM 613 N LYS A 513 8.084 -6.231 -14.082 1.00 87.89 N ANISOU 613 N LYS A 513 8915 13299 11179 2609 -634 -2945 N ATOM 614 CA LYS A 513 7.700 -7.270 -15.036 1.00102.77 C ANISOU 614 CA LYS A 513 10515 15344 13190 2678 -884 -3345 C ATOM 615 C LYS A 513 6.641 -6.668 -15.956 1.00111.47 C ANISOU 615 C LYS A 513 11449 16815 14090 2868 -929 -3384 C ATOM 616 O LYS A 513 6.567 -7.017 -17.131 1.00119.89 O ANISOU 616 O LYS A 513 12318 18208 15028 3035 -1115 -3685 O ATOM 617 CB LYS A 513 7.162 -8.502 -14.331 1.00102.37 C ANISOU 617 CB LYS A 513 10318 14951 13628 2473 -999 -3483 C ATOM 618 N LYS A 514 5.845 -5.748 -15.408 1.00 99.65 N ANISOU 618 N LYS A 514 10029 15287 12546 2865 -758 -3084 N ATOM 619 CA LYS A 514 4.837 -5.013 -16.178 1.00110.32 C ANISOU 619 CA LYS A 514 11242 16981 13692 3053 -762 -3046 C ATOM 620 C LYS A 514 5.488 -3.871 -16.963 1.00117.59 C ANISOU 620 C LYS A 514 12276 18218 14186 3258 -676 -2874 C ATOM 621 O LYS A 514 5.919 -2.865 -16.384 1.00104.73 O ANISOU 621 O LYS A 514 10894 16455 12443 3244 -485 -2542 O ATOM 622 CB LYS A 514 3.737 -4.473 -15.253 1.00103.53 C ANISOU 622 CB LYS A 514 10415 15965 12958 2994 -607 -2782 C ATOM 623 N LYS A 515 5.528 -4.038 -18.285 1.00135.39 N ANISOU 623 N LYS A 515 14325 20900 16216 3455 -833 -3097 N ATOM 624 CA LYS A 515 6.259 -3.149 -19.185 1.00138.77 C ANISOU 624 CA LYS A 515 14788 21701 16237 3661 -781 -2936 C ATOM 625 C LYS A 515 7.712 -3.579 -19.242 1.00133.68 C ANISOU 625 C LYS A 515 14244 21019 15529 3626 -805 -3005 C ATOM 626 O LYS A 515 8.007 -4.744 -19.500 1.00134.19 O ANISOU 626 O LYS A 515 14186 21086 15715 3608 -980 -3377 O ATOM 627 CB LYS A 515 6.150 -1.697 -18.748 1.00139.76 C ANISOU 627 CB LYS A 515 15116 21751 16236 3689 -559 -2474 C TER 628 LYS A 515 ATOM 629 N MET B 439 42.833 -8.308 26.540 1.00187.88 N ANISOU 629 N MET B 439 27519 23150 20716 -4263 -4764 427 N ATOM 630 CA MET B 439 42.319 -8.595 25.207 1.00176.00 C ANISOU 630 CA MET B 439 25745 21574 19553 -4085 -4369 512 C ATOM 631 C MET B 439 42.047 -10.088 25.059 1.00155.69 C ANISOU 631 C MET B 439 22836 19284 17034 -3856 -4025 752 C ATOM 632 O MET B 439 42.911 -10.914 25.346 1.00148.61 O ANISOU 632 O MET B 439 21650 18621 16194 -3958 -4132 1055 O ATOM 633 CB MET B 439 43.317 -8.128 24.147 1.00184.23 C ANISOU 633 CB MET B 439 26483 22481 21036 -4325 -4533 735 C ATOM 634 CG MET B 439 42.670 -7.638 22.865 1.00184.62 C ANISOU 634 CG MET B 439 26476 22317 21353 -4185 -4244 647 C ATOM 635 SD MET B 439 43.803 -6.709 21.819 1.00196.38 S ANISOU 635 SD MET B 439 27710 23597 23308 -4464 -4500 859 S ATOM 636 CE MET B 439 45.193 -7.834 21.742 1.00211.37 C ANISOU 636 CE MET B 439 29106 25782 25424 -4610 -4635 1381 C ATOM 637 N CYS B 440 40.838 -10.429 24.616 1.00149.11 N ANISOU 637 N CYS B 440 22036 18420 16198 -3550 -3614 627 N ATOM 638 CA CYS B 440 40.451 -11.825 24.416 1.00127.85 C ANISOU 638 CA CYS B 440 19037 15948 13591 -3319 -3275 824 C ATOM 639 C CYS B 440 41.448 -12.536 23.498 1.00109.36 C ANISOU 639 C CYS B 440 16211 13705 11637 -3428 -3260 1182 C ATOM 640 O CYS B 440 41.697 -12.105 22.378 1.00127.18 O ANISOU 640 O CYS B 440 18329 15811 14182 -3485 -3232 1226 O ATOM 641 CB CYS B 440 39.025 -11.911 23.845 1.00124.11 C ANISOU 641 CB CYS B 440 18654 15365 13135 -3012 -2872 640 C ATOM 642 SG CYS B 440 38.257 -13.591 23.774 1.00 86.59 S ANISOU 642 SG CYS B 440 13599 10838 8463 -2694 -2456 817 S ATOM 643 N LEU B 441 42.036 -13.619 23.993 1.00 70.53 N ANISOU 643 N LEU B 441 11033 9046 6718 -3440 -3267 1459 N ATOM 644 CA LEU B 441 42.867 -14.496 23.177 1.00 80.73 C ANISOU 644 CA LEU B 441 11865 10450 8359 -3478 -3174 1823 C ATOM 645 C LEU B 441 42.071 -15.103 22.010 1.00 89.26 C ANISOU 645 C LEU B 441 12771 11467 9677 -3218 -2766 1802 C ATOM 646 O LEU B 441 42.673 -15.599 21.069 1.00 91.35 O ANISOU 646 O LEU B 441 12710 11755 10244 -3224 -2671 2045 O ATOM 647 CB LEU B 441 43.424 -15.628 24.029 1.00 96.82 C ANISOU 647 CB LEU B 441 13680 12785 10323 -3488 -3189 2107 C ATOM 648 CG LEU B 441 44.622 -15.251 24.906 1.00115.78 C ANISOU 648 CG LEU B 441 16092 15301 12600 -3797 -3621 2276 C ATOM 649 CD1 LEU B 441 45.928 -15.638 24.230 1.00123.24 C ANISOU 649 CD1 LEU B 441 16620 16315 13891 -3978 -3704 2705 C ATOM 650 CD2 LEU B 441 44.589 -13.764 25.233 1.00118.19 C ANISOU 650 CD2 LEU B 441 16804 15385 12718 -3979 -3958 1970 C ATOM 651 N VAL B 442 40.737 -15.084 22.088 1.00 84.11 N ANISOU 651 N VAL B 442 12336 10741 8883 -2985 -2530 1530 N ATOM 652 CA VAL B 442 39.891 -15.660 21.024 1.00 80.55 C ANISOU 652 CA VAL B 442 11736 10227 8644 -2746 -2169 1491 C ATOM 653 C VAL B 442 39.402 -14.618 20.029 1.00 83.46 C ANISOU 653 C VAL B 442 12247 10359 9106 -2730 -2124 1280 C ATOM 654 O VAL B 442 39.766 -14.648 18.854 1.00 82.42 O ANISOU 654 O VAL B 442 11895 10175 9247 -2732 -2051 1386 O ATOM 655 CB VAL B 442 38.633 -16.361 21.579 1.00 71.86 C ANISOU 655 CB VAL B 442 10725 9183 7394 -2478 -1906 1371 C ATOM 656 CG1 VAL B 442 37.834 -17.003 20.430 1.00 71.78 C ANISOU 656 CG1 VAL B 442 10534 9101 7638 -2264 -1577 1347 C ATOM 657 CG2 VAL B 442 39.013 -17.415 22.586 1.00 72.54 C ANISOU 657 CG2 VAL B 442 10651 9516 7395 -2457 -1914 1589 C ATOM 658 N CYS B 443 38.549 -13.710 20.487 1.00 85.97 N ANISOU 658 N CYS B 443 12933 10540 9192 -2689 -2142 993 N ATOM 659 CA CYS B 443 37.973 -12.724 19.589 1.00 79.74 C ANISOU 659 CA CYS B 443 12278 9532 8487 -2654 -2061 799 C ATOM 660 C CYS B 443 38.648 -11.366 19.719 1.00 96.71 C ANISOU 660 C CYS B 443 14621 11522 10601 -2899 -2373 718 C ATOM 661 O CYS B 443 38.208 -10.395 19.110 1.00 93.31 O ANISOU 661 O CYS B 443 14329 10897 10227 -2888 -2328 554 O ATOM 662 CB CYS B 443 36.463 -12.604 19.818 1.00 81.41 C ANISOU 662 CB CYS B 443 12746 9666 8521 -2416 -1814 558 C ATOM 663 SG CYS B 443 35.958 -11.427 21.094 1.00 81.55 S ANISOU 663 SG CYS B 443 13292 9559 8136 -2446 -1971 282 S ATOM 664 N SER B 444 39.727 -11.321 20.504 1.00106.69 N ANISOU 664 N SER B 444 15874 12869 11793 -3125 -2693 850 N ATOM 665 CA SER B 444 40.496 -10.095 20.773 1.00112.58 C ANISOU 665 CA SER B 444 16795 13460 12521 -3399 -3059 793 C ATOM 666 C SER B 444 39.646 -8.862 21.093 1.00113.86 C ANISOU 666 C SER B 444 17400 13384 12479 -3375 -3082 435 C ATOM 667 O SER B 444 40.093 -7.735 20.907 1.00127.60 O ANISOU 667 O SER B 444 19254 14922 14306 -3565 -3308 362 O ATOM 668 CB SER B 444 41.473 -9.792 19.632 1.00116.49 C ANISOU 668 CB SER B 444 16973 13888 13398 -3544 -3149 1030 C ATOM 669 OG SER B 444 42.496 -10.771 19.571 1.00114.55 O ANISOU 669 OG SER B 444 16368 13850 13306 -3618 -3208 1389 O ATOM 670 N ASP B 445 38.429 -9.082 21.583 1.00108.33 N ANISOU 670 N ASP B 445 16940 12698 11525 -3133 -2841 235 N ATOM 671 CA ASP B 445 37.671 -8.042 22.263 1.00105.47 C ANISOU 671 CA ASP B 445 17055 12146 10873 -3093 -2878 -85 C ATOM 672 C ASP B 445 38.510 -7.745 23.496 1.00132.55 C ANISOU 672 C ASP B 445 20695 15616 14051 -3311 -3283 -120 C ATOM 673 O ASP B 445 39.731 -7.881 23.450 1.00144.39 O ANISOU 673 O ASP B 445 21961 17190 15711 -3558 -3564 90 O ATOM 674 CB ASP B 445 36.293 -8.575 22.659 1.00 84.79 C ANISOU 674 CB ASP B 445 14598 9591 8029 -2766 -2533 -200 C ATOM 675 CG ASP B 445 35.239 -7.486 22.747 1.00 88.60 C ANISOU 675 CG ASP B 445 15490 9833 8341 -2642 -2403 -488 C ATOM 676 OD1 ASP B 445 35.599 -6.306 22.548 1.00 93.76 O ANISOU 676 OD1 ASP B 445 16316 10262 9045 -2820 -2591 -623 O ATOM 677 OD2 ASP B 445 34.046 -7.815 22.994 1.00 82.78 O ANISOU 677 OD2 ASP B 445 14885 9123 7445 -2361 -2102 -554 O ATOM 678 N GLU B 446 37.902 -7.361 24.609 1.00139.83 N ANISOU 678 N GLU B 446 22053 16502 14575 -3218 -3325 -365 N ATOM 679 CA GLU B 446 38.674 -7.380 25.850 1.00153.27 C ANISOU 679 CA GLU B 446 23919 18324 15994 -3385 -3694 -371 C ATOM 680 C GLU B 446 38.016 -8.124 26.990 1.00148.58 C ANISOU 680 C GLU B 446 23499 17949 15007 -3137 -3562 -407 C ATOM 681 O GLU B 446 36.795 -8.135 27.157 1.00134.66 O ANISOU 681 O GLU B 446 21953 16146 13068 -2838 -3249 -551 O ATOM 682 CB GLU B 446 39.159 -5.997 26.290 1.00173.55 C ANISOU 682 CB GLU B 446 26862 20634 18444 -3637 -4088 -612 C ATOM 683 CG GLU B 446 40.684 -5.917 26.276 1.00193.70 C ANISOU 683 CG GLU B 446 29171 23227 21200 -4013 -4530 -399 C ATOM 684 CD GLU B 446 41.264 -5.188 27.470 1.00216.74 C ANISOU 684 CD GLU B 446 32472 26079 23801 -4238 -5006 -590 C ATOM 685 OE1 GLU B 446 42.060 -5.802 28.216 1.00226.13 O ANISOU 685 OE1 GLU B 446 33545 27514 24860 -4372 -5261 -416 O ATOM 686 OE2 GLU B 446 40.926 -4.005 27.666 1.00224.02 O ANISOU 686 OE2 GLU B 446 33812 26703 24602 -4282 -5127 -912 O ATOM 687 N ALA B 447 38.885 -8.732 27.783 1.00165.20 N ANISOU 687 N ALA B 447 25486 20296 16988 -3265 -3811 -239 N ATOM 688 CA ALA B 447 38.513 -9.798 28.688 1.00167.35 C ANISOU 688 CA ALA B 447 25720 20865 17000 -3036 -3660 -129 C ATOM 689 C ALA B 447 37.846 -9.330 29.970 1.00156.51 C ANISOU 689 C ALA B 447 24868 19494 15104 -2858 -3709 -395 C ATOM 690 O ALA B 447 38.004 -8.193 30.412 1.00159.58 O ANISOU 690 O ALA B 447 25676 19685 15273 -2993 -3990 -669 O ATOM 691 CB ALA B 447 39.737 -10.611 29.024 1.00177.11 C ANISOU 691 CB ALA B 447 26607 22376 18312 -3242 -3897 183 C ATOM 692 N SER B 448 37.089 -10.249 30.551 1.00139.85 N ANISOU 692 N SER B 448 22720 17606 12810 -2536 -3422 -299 N ATOM 693 CA SER B 448 36.509 -10.071 31.867 1.00129.50 C ANISOU 693 CA SER B 448 21839 16385 10979 -2305 -3434 -466 C ATOM 694 C SER B 448 37.419 -10.759 32.883 1.00136.50 C ANISOU 694 C SER B 448 22597 17612 11653 -2401 -3698 -280 C ATOM 695 O SER B 448 37.408 -10.432 34.069 1.00145.98 O ANISOU 695 O SER B 448 24175 18907 12382 -2328 -3887 -431 O ATOM 696 CB SER B 448 35.092 -10.654 31.908 1.00114.12 C ANISOU 696 CB SER B 448 19903 14484 8975 -1863 -2943 -423 C ATOM 697 OG SER B 448 35.000 -11.905 31.231 1.00 98.66 O ANISOU 697 OG SER B 448 17405 12687 7395 -1781 -2668 -107 O ATOM 698 N GLY B 449 38.219 -11.707 32.398 1.00131.34 N ANISOU 698 N GLY B 449 21413 17148 11344 -2557 -3706 56 N ATOM 699 CA GLY B 449 39.197 -12.396 33.221 1.00125.79 C ANISOU 699 CA GLY B 449 20506 16777 10511 -2687 -3950 293 C ATOM 700 C GLY B 449 39.645 -13.690 32.570 1.00120.36 C ANISOU 700 C GLY B 449 19197 16289 10243 -2710 -3750 701 C ATOM 701 O GLY B 449 39.592 -13.840 31.343 1.00112.59 O ANISOU 701 O GLY B 449 17946 15147 9685 -2755 -3566 778 O ATOM 702 N CYS B 450 40.066 -14.642 33.395 1.00101.41 N ANISOU 702 N CYS B 450 16573 14244 7716 -2659 -3769 966 N ATOM 703 CA CYS B 450 40.503 -15.943 32.904 1.00103.35 C ANISOU 703 CA CYS B 450 16235 14692 8340 -2659 -3562 1369 C ATOM 704 C CYS B 450 39.358 -16.959 33.024 1.00101.50 C ANISOU 704 C CYS B 450 15849 14574 8142 -2242 -3087 1473 C ATOM 705 O CYS B 450 38.851 -17.181 34.117 1.00 98.67 O ANISOU 705 O CYS B 450 15656 14409 7425 -1996 -3025 1462 O ATOM 706 CB CYS B 450 41.716 -16.389 33.720 1.00114.21 C ANISOU 706 CB CYS B 450 17409 16390 9594 -2872 -3866 1644 C ATOM 707 SG CYS B 450 42.803 -17.606 32.971 1.00134.44 S ANISOU 707 SG CYS B 450 19280 19133 12667 -3049 -3772 2155 S ATOM 708 N HIS B 451 38.937 -17.551 31.904 1.00108.06 N ANISOU 708 N HIS B 451 16372 15280 9405 -2153 -2762 1575 N ATOM 709 CA HIS B 451 37.851 -18.536 31.901 1.00 97.92 C ANISOU 709 CA HIS B 451 14906 14065 8235 -1784 -2329 1688 C ATOM 710 C HIS B 451 38.220 -19.859 31.237 1.00 88.14 C ANISOU 710 C HIS B 451 13102 12938 7450 -1784 -2106 2034 C ATOM 711 O HIS B 451 38.799 -19.880 30.153 1.00 76.02 O ANISOU 711 O HIS B 451 11357 11270 6256 -1985 -2133 2089 O ATOM 712 CB HIS B 451 36.629 -17.972 31.178 1.00 94.14 C ANISOU 712 CB HIS B 451 14660 13279 7831 -1606 -2098 1426 C ATOM 713 CG HIS B 451 36.141 -16.679 31.744 1.00 94.53 C ANISOU 713 CG HIS B 451 15276 13176 7464 -1566 -2251 1084 C ATOM 714 ND1 HIS B 451 35.468 -16.599 32.946 1.00100.98 N ANISOU 714 ND1 HIS B 451 16391 14123 7855 -1288 -2196 1020 N ATOM 715 CD2 HIS B 451 36.229 -15.413 31.275 1.00 91.96 C ANISOU 715 CD2 HIS B 451 15278 12573 7090 -1753 -2443 794 C ATOM 716 CE1 HIS B 451 35.165 -15.337 33.193 1.00103.57 C ANISOU 716 CE1 HIS B 451 17233 14248 7871 -1306 -2348 688 C ATOM 717 NE2 HIS B 451 35.610 -14.599 32.191 1.00102.32 N ANISOU 717 NE2 HIS B 451 17095 13834 7950 -1594 -2500 544 N ATOM 718 N TYR B 452 37.853 -20.958 31.887 1.00 87.55 N ANISOU 718 N TYR B 452 12787 13100 7380 -1533 -1871 2271 N ATOM 719 CA TYR B 452 38.093 -22.299 31.362 1.00 86.30 C ANISOU 719 CA TYR B 452 12100 13039 7652 -1491 -1624 2599 C ATOM 720 C TYR B 452 39.510 -22.477 30.836 1.00 96.45 C ANISOU 720 C TYR B 452 13107 14379 9159 -1825 -1818 2802 C ATOM 721 O TYR B 452 39.710 -23.119 29.811 1.00 92.39 O ANISOU 721 O TYR B 452 12276 13770 9058 -1857 -1646 2937 O ATOM 722 CB TYR B 452 37.084 -22.627 30.250 1.00 78.80 C ANISOU 722 CB TYR B 452 11051 11829 7062 -1319 -1302 2510 C ATOM 723 CG TYR B 452 35.635 -22.511 30.692 1.00 71.51 C ANISOU 723 CG TYR B 452 10355 10838 5978 -978 -1082 2370 C ATOM 724 CD1 TYR B 452 35.138 -23.273 31.744 1.00 74.06 C ANISOU 724 CD1 TYR B 452 10567 11393 6181 -692 -908 2571 C ATOM 725 CD2 TYR B 452 34.765 -21.634 30.057 1.00 71.07 C ANISOU 725 CD2 TYR B 452 10606 10495 5901 -926 -1033 2073 C ATOM 726 CE1 TYR B 452 33.813 -23.156 32.148 1.00 80.68 C ANISOU 726 CE1 TYR B 452 11601 12168 6885 -357 -695 2491 C ATOM 727 CE2 TYR B 452 33.439 -21.516 30.457 1.00 60.18 C ANISOU 727 CE2 TYR B 452 9428 9052 4386 -607 -818 1989 C ATOM 728 CZ TYR B 452 32.967 -22.281 31.471 1.00 73.25 C ANISOU 728 CZ TYR B 452 10969 10926 5936 -322 -649 2204 C ATOM 729 OH TYR B 452 31.651 -22.135 31.834 1.00 80.53 O ANISOU 729 OH TYR B 452 12082 11776 6740 11 -427 2158 O ATOM 730 N GLY B 453 40.483 -21.903 31.543 1.00100.62 N ANISOU 730 N GLY B 453 13765 15058 9409 -2064 -2181 2832 N ATOM 731 CA GLY B 453 41.892 -22.122 31.252 1.00108.49 C ANISOU 731 CA GLY B 453 14470 16158 10592 -2375 -2380 3108 C ATOM 732 C GLY B 453 42.576 -21.030 30.446 1.00115.19 C ANISOU 732 C GLY B 453 15479 16769 11519 -2689 -2675 2959 C ATOM 733 O GLY B 453 43.788 -21.083 30.238 1.00123.45 O ANISOU 733 O GLY B 453 16303 17892 12709 -2957 -2876 3209 O ATOM 734 N VAL B 454 41.811 -20.034 30.006 1.00108.38 N ANISOU 734 N VAL B 454 14983 15621 10576 -2649 -2694 2585 N ATOM 735 CA VAL B 454 42.309 -19.035 29.061 1.00100.91 C ANISOU 735 CA VAL B 454 14147 14413 9781 -2901 -2903 2450 C ATOM 736 C VAL B 454 41.748 -17.651 29.360 1.00 93.58 C ANISOU 736 C VAL B 454 13745 13274 8539 -2928 -3104 2038 C ATOM 737 O VAL B 454 40.665 -17.526 29.906 1.00 84.40 O ANISOU 737 O VAL B 454 12855 12092 7122 -2677 -2955 1823 O ATOM 738 CB VAL B 454 41.909 -19.417 27.608 1.00 83.25 C ANISOU 738 CB VAL B 454 11691 11972 7967 -2796 -2589 2459 C ATOM 739 CG1 VAL B 454 42.260 -18.300 26.628 1.00 77.79 C ANISOU 739 CG1 VAL B 454 11134 11009 7412 -3000 -2770 2304 C ATOM 740 CG2 VAL B 454 42.566 -20.723 27.205 1.00 87.35 C ANISOU 740 CG2 VAL B 454 11714 12655 8819 -2784 -2401 2855 C ATOM 741 N LEU B 455 42.485 -16.614 28.989 1.00 99.23 N ANISOU 741 N LEU B 455 14592 13819 9292 -3222 -3432 1950 N ATOM 742 CA LEU B 455 42.009 -15.241 29.117 1.00110.38 C ANISOU 742 CA LEU B 455 16492 14977 10472 -3269 -3617 1556 C ATOM 743 C LEU B 455 41.045 -14.887 27.980 1.00100.33 C ANISOU 743 C LEU B 455 15286 13422 9413 -3110 -3326 1352 C ATOM 744 O LEU B 455 41.452 -14.799 26.824 1.00 96.04 O ANISOU 744 O LEU B 455 14519 12746 9227 -3221 -3292 1447 O ATOM 745 CB LEU B 455 43.207 -14.291 29.097 1.00129.83 C ANISOU 745 CB LEU B 455 19023 17345 12962 -3660 -4088 1571 C ATOM 746 CG LEU B 455 42.921 -12.799 28.946 1.00140.38 C ANISOU 746 CG LEU B 455 20798 18352 14189 -3770 -4299 1193 C ATOM 747 CD1 LEU B 455 41.853 -12.360 29.916 1.00138.08 C ANISOU 747 CD1 LEU B 455 20995 18030 13439 -3545 -4250 843 C ATOM 748 CD2 LEU B 455 44.200 -12.007 29.157 1.00153.66 C ANISOU 748 CD2 LEU B 455 22510 19976 15896 -4173 -4814 1259 C ATOM 749 N THR B 456 39.777 -14.659 28.311 1.00 91.76 N ANISOU 749 N THR B 456 14508 12254 8101 -2840 -3117 1093 N ATOM 750 CA THR B 456 38.753 -14.455 27.290 1.00 95.98 C ANISOU 750 CA THR B 456 15077 12560 8831 -2661 -2807 936 C ATOM 751 C THR B 456 37.725 -13.411 27.704 1.00 99.95 C ANISOU 751 C THR B 456 16083 12869 9025 -2522 -2781 581 C ATOM 752 O THR B 456 37.568 -13.119 28.899 1.00 97.33 O ANISOU 752 O THR B 456 16072 12616 8291 -2462 -2914 461 O ATOM 753 CB THR B 456 37.999 -15.763 27.011 1.00 83.74 C ANISOU 753 CB THR B 456 13223 11134 7458 -2374 -2401 1105 C ATOM 754 OG1 THR B 456 37.002 -15.960 28.018 1.00 89.63 O ANISOU 754 OG1 THR B 456 14195 11968 7892 -2096 -2249 1016 O ATOM 755 CG2 THR B 456 38.951 -16.945 27.029 1.00 84.99 C ANISOU 755 CG2 THR B 456 12933 11538 7821 -2456 -2407 1468 C ATOM 756 N CYS B 457 37.044 -12.849 26.707 1.00106.02 N ANISOU 756 N CYS B 457 16919 13389 9974 -2460 -2602 426 N ATOM 757 CA CYS B 457 35.902 -11.969 26.919 1.00101.98 C ANISOU 757 CA CYS B 457 16837 12681 9232 -2279 -2476 132 C ATOM 758 C CYS B 457 34.767 -12.795 27.493 1.00 92.05 C ANISOU 758 C CYS B 457 15594 11557 7823 -1917 -2147 183 C ATOM 759 O CYS B 457 34.795 -14.023 27.439 1.00 94.91 O ANISOU 759 O CYS B 457 15591 12117 8353 -1817 -1987 430 O ATOM 760 CB CYS B 457 35.459 -11.308 25.600 1.00103.81 C ANISOU 760 CB CYS B 457 17047 12649 9746 -2293 -2326 19 C ATOM 761 SG CYS B 457 34.526 -12.372 24.406 1.00 79.12 S ANISOU 761 SG CYS B 457 13532 9548 6982 -2043 -1872 171 S ATOM 762 N GLY B 458 33.762 -12.121 28.040 1.00 83.84 N ANISOU 762 N GLY B 458 14970 10400 6486 -1709 -2036 -30 N ATOM 763 CA GLY B 458 32.592 -12.799 28.571 1.00 73.83 C ANISOU 763 CA GLY B 458 13729 9235 5087 -1335 -1706 45 C ATOM 764 C GLY B 458 31.784 -13.485 27.469 1.00 76.93 C ANISOU 764 C GLY B 458 13793 9570 5867 -1185 -1358 171 C ATOM 765 O GLY B 458 31.230 -14.562 27.690 1.00 80.82 O ANISOU 765 O GLY B 458 14055 10213 6439 -957 -1127 369 O ATOM 766 N SER B 459 31.692 -12.886 26.289 1.00 80.24 N ANISOU 766 N SER B 459 14179 9774 6534 -1302 -1322 66 N ATOM 767 CA SER B 459 30.862 -13.504 25.245 1.00 74.81 C ANISOU 767 CA SER B 459 13209 9034 6181 -1152 -1009 163 C ATOM 768 C SER B 459 31.480 -14.845 24.818 1.00 76.25 C ANISOU 768 C SER B 459 12899 9397 6677 -1207 -987 413 C ATOM 769 O SER B 459 30.770 -15.840 24.637 1.00 78.12 O ANISOU 769 O SER B 459 12897 9695 7090 -1005 -738 559 O ATOM 770 CB SER B 459 30.608 -12.556 24.060 1.00 70.80 C ANISOU 770 CB SER B 459 12768 8282 5851 -1246 -966 4 C ATOM 771 OG SER B 459 31.753 -12.396 23.227 1.00 78.65 O ANISOU 771 OG SER B 459 13547 9255 7081 -1530 -1172 28 O ATOM 772 N CYS B 460 32.802 -14.879 24.717 1.00 75.98 N ANISOU 772 N CYS B 460 12717 9440 6713 -1475 -1248 480 N ATOM 773 CA CYS B 460 33.516 -16.114 24.411 1.00 80.11 C ANISOU 773 CA CYS B 460 12797 10137 7505 -1530 -1232 736 C ATOM 774 C CYS B 460 33.463 -17.158 25.509 1.00 78.65 C ANISOU 774 C CYS B 460 12490 10191 7203 -1379 -1167 930 C ATOM 775 O CYS B 460 33.522 -18.361 25.232 1.00 68.35 O ANISOU 775 O CYS B 460 10813 8998 6160 -1306 -1015 1143 O ATOM 776 CB CYS B 460 34.960 -15.804 24.096 1.00 85.24 C ANISOU 776 CB CYS B 460 13332 10809 8244 -1846 -1526 799 C ATOM 777 SG CYS B 460 35.049 -15.085 22.487 1.00 80.03 S ANISOU 777 SG CYS B 460 12605 9919 7883 -1962 -1504 698 S ATOM 778 N LYS B 461 33.363 -16.706 26.753 1.00 80.33 N ANISOU 778 N LYS B 461 13014 10483 7023 -1319 -1280 859 N ATOM 779 CA LYS B 461 33.149 -17.620 27.859 1.00 83.15 C ANISOU 779 CA LYS B 461 13279 11082 7232 -1116 -1184 1047 C ATOM 780 C LYS B 461 31.887 -18.451 27.634 1.00 77.29 C ANISOU 780 C LYS B 461 12367 10316 6684 -799 -815 1152 C ATOM 781 O LYS B 461 31.935 -19.692 27.620 1.00 69.13 O ANISOU 781 O LYS B 461 10949 9423 5894 -711 -671 1398 O ATOM 782 CB LYS B 461 33.062 -16.847 29.190 1.00 89.68 C ANISOU 782 CB LYS B 461 14546 11977 7553 -1049 -1345 910 C ATOM 783 CG LYS B 461 32.140 -17.468 30.235 1.00 88.36 C ANISOU 783 CG LYS B 461 14420 11974 7179 -681 -1117 1034 C ATOM 784 CD LYS B 461 32.356 -16.840 31.628 1.00 91.41 C ANISOU 784 CD LYS B 461 15210 12495 7027 -630 -1325 929 C ATOM 785 CE LYS B 461 31.197 -17.131 32.587 1.00 96.85 C ANISOU 785 CE LYS B 461 16054 13287 7458 -195 -1058 1007 C ATOM 786 NZ LYS B 461 29.945 -16.440 32.163 1.00108.61 N ANISOU 786 NZ LYS B 461 17822 14508 8936 6 -828 842 N ATOM 787 N VAL B 462 30.757 -17.762 27.474 1.00 76.13 N ANISOU 787 N VAL B 462 12499 9983 6444 -629 -664 983 N ATOM 788 CA VAL B 462 29.460 -18.425 27.362 1.00 72.87 C ANISOU 788 CA VAL B 462 11961 9534 6193 -320 -333 1098 C ATOM 789 C VAL B 462 29.360 -19.246 26.060 1.00 61.92 C ANISOU 789 C VAL B 462 10169 8061 5296 -371 -198 1186 C ATOM 790 O VAL B 462 28.774 -20.342 26.049 1.00 59.61 O ANISOU 790 O VAL B 462 9583 7820 5245 -183 11 1384 O ATOM 791 CB VAL B 462 28.323 -17.394 27.381 1.00 76.89 C ANISOU 791 CB VAL B 462 12865 9846 6503 -150 -207 914 C ATOM 792 CG1 VAL B 462 28.309 -16.670 28.693 1.00 76.15 C ANISOU 792 CG1 VAL B 462 13195 9825 5911 -43 -307 823 C ATOM 793 CG2 VAL B 462 28.483 -16.397 26.194 1.00 71.93 C ANISOU 793 CG2 VAL B 462 12354 8981 5994 -376 -293 682 C ATOM 794 N PHE B 463 29.935 -18.717 24.983 1.00 65.64 N ANISOU 794 N PHE B 463 10626 8401 5914 -613 -322 1045 N ATOM 795 CA PHE B 463 29.914 -19.417 23.699 1.00 65.78 C ANISOU 795 CA PHE B 463 10302 8340 6351 -657 -215 1097 C ATOM 796 C PHE B 463 30.547 -20.779 23.862 1.00 67.84 C ANISOU 796 C PHE B 463 10169 8773 6832 -661 -189 1344 C ATOM 797 O PHE B 463 30.003 -21.783 23.417 1.00 55.40 O ANISOU 797 O PHE B 463 8314 7173 5562 -529 0 1459 O ATOM 798 CB PHE B 463 30.675 -18.650 22.622 1.00 61.23 C ANISOU 798 CB PHE B 463 9756 7646 5864 -910 -375 948 C ATOM 799 CG PHE B 463 30.856 -19.435 21.340 1.00 64.93 C ANISOU 799 CG PHE B 463 9876 8071 6724 -947 -288 1012 C ATOM 800 CD1 PHE B 463 32.048 -20.091 21.067 1.00 60.72 C ANISOU 800 CD1 PHE B 463 9071 7644 6354 -1097 -389 1158 C ATOM 801 CD2 PHE B 463 29.811 -19.536 20.412 1.00 57.31 C ANISOU 801 CD2 PHE B 463 8859 6960 5954 -818 -101 937 C ATOM 802 CE1 PHE B 463 32.207 -20.830 19.895 1.00 60.74 C ANISOU 802 CE1 PHE B 463 8786 7600 6692 -1098 -294 1208 C ATOM 803 CE2 PHE B 463 29.972 -20.260 19.226 1.00 54.10 C ANISOU 803 CE2 PHE B 463 8163 6513 5878 -839 -37 968 C ATOM 804 CZ PHE B 463 31.174 -20.905 18.963 1.00 55.31 C ANISOU 804 CZ PHE B 463 8076 6763 6175 -969 -128 1093 C ATOM 805 N PHE B 464 31.708 -20.809 24.510 1.00 61.47 N ANISOU 805 N PHE B 464 9338 8136 5882 -820 -386 1433 N ATOM 806 CA PHE B 464 32.437 -22.063 24.708 1.00 53.41 C ANISOU 806 CA PHE B 464 7934 7296 5062 -840 -359 1698 C ATOM 807 C PHE B 464 31.654 -23.049 25.530 1.00 54.09 C ANISOU 807 C PHE B 464 7863 7497 5192 -568 -146 1889 C ATOM 808 O PHE B 464 31.485 -24.216 25.147 1.00 58.70 O ANISOU 808 O PHE B 464 8093 8084 6124 -479 26 2056 O ATOM 809 CB PHE B 464 33.788 -21.800 25.390 1.00 65.25 C ANISOU 809 CB PHE B 464 9460 8978 6355 -1062 -624 1784 C ATOM 810 CG PHE B 464 34.654 -23.026 25.501 1.00 69.63 C ANISOU 810 CG PHE B 464 9607 9719 7131 -1107 -591 2084 C ATOM 811 CD1 PHE B 464 35.214 -23.602 24.375 1.00 65.25 C ANISOU 811 CD1 PHE B 464 8765 9095 6932 -1207 -538 2167 C ATOM 812 CD2 PHE B 464 34.909 -23.603 26.740 1.00 77.64 C ANISOU 812 CD2 PHE B 464 10526 10987 7988 -1031 -596 2296 C ATOM 813 CE1 PHE B 464 36.021 -24.732 24.484 1.00 77.72 C ANISOU 813 CE1 PHE B 464 9976 10834 8719 -1237 -481 2460 C ATOM 814 CE2 PHE B 464 35.712 -24.723 26.841 1.00 75.01 C ANISOU 814 CE2 PHE B 464 9800 10829 7872 -1073 -543 2597 C ATOM 815 CZ PHE B 464 36.264 -25.288 25.713 1.00 70.55 C ANISOU 815 CZ PHE B 464 8958 10172 7675 -1178 -479 2680 C ATOM 816 N LYS B 465 31.186 -22.608 26.691 1.00 60.82 N ANISOU 816 N LYS B 465 8972 8442 5695 -419 -154 1878 N ATOM 817 CA LYS B 465 30.403 -23.494 27.525 1.00 65.46 C ANISOU 817 CA LYS B 465 9404 9151 6316 -122 62 2096 C ATOM 818 C LYS B 465 29.290 -24.098 26.659 1.00 66.19 C ANISOU 818 C LYS B 465 9303 9050 6797 41 308 2120 C ATOM 819 O LYS B 465 29.074 -25.307 26.647 1.00 64.04 O ANISOU 819 O LYS B 465 8664 8820 6848 163 472 2343 O ATOM 820 CB LYS B 465 29.819 -22.735 28.715 1.00 71.32 C ANISOU 820 CB LYS B 465 10526 9969 6604 70 51 2038 C ATOM 821 CG LYS B 465 28.856 -23.560 29.542 1.00 75.61 C ANISOU 821 CG LYS B 465 10920 10624 7185 432 306 2288 C ATOM 822 CD LYS B 465 29.477 -24.878 29.925 1.00 85.11 C ANISOU 822 CD LYS B 465 11673 12049 8616 450 364 2599 C ATOM 823 CE LYS B 465 29.044 -25.304 31.327 1.00 93.75 C ANISOU 823 CE LYS B 465 12741 13387 9491 771 492 2845 C ATOM 824 NZ LYS B 465 29.788 -26.512 31.805 1.00 95.12 N ANISOU 824 NZ LYS B 465 12475 13815 9851 773 535 3165 N ATOM 825 N ARG B 466 28.588 -23.242 25.932 1.00 67.33 N ANISOU 825 N ARG B 466 9687 8975 6919 34 324 1896 N ATOM 826 CA ARG B 466 27.474 -23.703 25.108 1.00 74.11 C ANISOU 826 CA ARG B 466 10391 9649 8118 175 526 1909 C ATOM 827 C ARG B 466 27.943 -24.647 23.994 1.00 65.46 C ANISOU 827 C ARG B 466 8929 8488 7456 44 540 1945 C ATOM 828 O ARG B 466 27.303 -25.661 23.737 1.00 65.31 O ANISOU 828 O ARG B 466 8626 8408 7780 184 702 2084 O ATOM 829 CB ARG B 466 26.690 -22.506 24.537 1.00 69.01 C ANISOU 829 CB ARG B 466 10082 8802 7336 178 535 1671 C ATOM 830 CG ARG B 466 25.737 -21.898 25.575 1.00 68.60 C ANISOU 830 CG ARG B 466 10336 8765 6963 430 642 1701 C ATOM 831 CD ARG B 466 25.432 -20.408 25.300 1.00 67.40 C ANISOU 831 CD ARG B 466 10618 8458 6533 369 585 1438 C ATOM 832 NE ARG B 466 24.422 -19.923 26.256 1.00 75.66 N ANISOU 832 NE ARG B 466 11951 9502 7294 656 734 1494 N ATOM 833 CZ ARG B 466 24.016 -18.655 26.380 1.00 73.84 C ANISOU 833 CZ ARG B 466 12146 9152 6758 686 734 1310 C ATOM 834 NH1 ARG B 466 24.528 -17.702 25.628 1.00 64.60 N ANISOU 834 NH1 ARG B 466 11153 7854 5539 435 582 1055 N ATOM 835 NH2 ARG B 466 23.094 -18.343 27.283 1.00 81.70 N ANISOU 835 NH2 ARG B 466 13387 10155 7502 989 902 1402 N ATOM 836 N ALA B 467 29.075 -24.340 23.361 1.00 61.42 N ANISOU 836 N ALA B 467 8420 7982 6935 -211 369 1838 N ATOM 837 CA ALA B 467 29.566 -25.162 22.262 1.00 55.86 C ANISOU 837 CA ALA B 467 7413 7211 6602 -312 390 1862 C ATOM 838 C ALA B 467 29.871 -26.588 22.755 1.00 66.39 C ANISOU 838 C ALA B 467 8371 8670 8184 -227 500 2140 C ATOM 839 O ALA B 467 29.459 -27.577 22.149 1.00 68.60 O ANISOU 839 O ALA B 467 8384 8844 8838 -145 636 2202 O ATOM 840 CB ALA B 467 30.789 -24.548 21.667 1.00 53.81 C ANISOU 840 CB ALA B 467 7222 6965 6257 -567 199 1762 C ATOM 841 N VAL B 468 30.594 -26.678 23.858 1.00 62.40 N ANISOU 841 N VAL B 468 7847 8389 7473 -250 435 2306 N ATOM 842 CA VAL B 468 31.044 -27.965 24.387 1.00 73.89 C ANISOU 842 CA VAL B 468 8932 9998 9144 -186 539 2600 C ATOM 843 C VAL B 468 29.900 -28.838 24.901 1.00 82.05 C ANISOU 843 C VAL B 468 9771 11013 10390 96 763 2773 C ATOM 844 O VAL B 468 29.869 -30.045 24.672 1.00 87.07 O ANISOU 844 O VAL B 468 10049 11618 11415 165 904 2945 O ATOM 845 CB VAL B 468 32.034 -27.729 25.525 1.00 69.99 C ANISOU 845 CB VAL B 468 8486 9778 8327 -272 401 2744 C ATOM 846 CG1 VAL B 468 32.060 -28.912 26.485 1.00 73.51 C ANISOU 846 CG1 VAL B 468 8599 10425 8905 -103 557 3078 C ATOM 847 CG2 VAL B 468 33.414 -27.445 24.948 1.00 62.76 C ANISOU 847 CG2 VAL B 468 7553 8897 7397 -558 215 2721 C ATOM 848 N GLU B 469 28.973 -28.208 25.609 1.00 83.96 N ANISOU 848 N GLU B 469 10252 11266 10383 269 797 2742 N ATOM 849 CA GLU B 469 27.848 -28.892 26.221 1.00 95.55 C ANISOU 849 CA GLU B 469 11557 12731 12016 566 1007 2950 C ATOM 850 C GLU B 469 26.875 -29.402 25.171 1.00103.23 C ANISOU 850 C GLU B 469 12371 13432 13419 629 1125 2899 C ATOM 851 O GLU B 469 26.606 -30.598 25.074 1.00111.72 O ANISOU 851 O GLU B 469 13080 14459 14910 731 1262 3093 O ATOM 852 CB GLU B 469 27.101 -27.908 27.113 1.00102.23 C ANISOU 852 CB GLU B 469 12763 13633 12448 740 1012 2909 C ATOM 853 CG GLU B 469 26.601 -28.502 28.397 1.00115.83 C ANISOU 853 CG GLU B 469 14343 15542 14125 1044 1175 3223 C ATOM 854 CD GLU B 469 27.577 -28.296 29.533 1.00124.36 C ANISOU 854 CD GLU B 469 15513 16932 14808 1015 1059 3310 C ATOM 855 OE1 GLU B 469 27.245 -27.504 30.442 1.00126.10 O ANISOU 855 OE1 GLU B 469 16063 17258 14592 1166 1035 3277 O ATOM 856 OE2 GLU B 469 28.674 -28.904 29.508 1.00125.05 O ANISOU 856 OE2 GLU B 469 15354 17153 15006 844 990 3410 O ATOM 857 N GLY B 470 26.346 -28.463 24.394 1.00 94.34 N ANISOU 857 N GLY B 470 11525 12128 12192 566 1064 2639 N ATOM 858 CA GLY B 470 25.312 -28.736 23.416 1.00 88.55 C ANISOU 858 CA GLY B 470 10702 11147 11797 623 1146 2568 C ATOM 859 C GLY B 470 25.744 -29.565 22.220 1.00 89.57 C ANISOU 859 C GLY B 470 10575 11138 12318 480 1121 2491 C ATOM 860 O GLY B 470 24.913 -29.931 21.396 1.00 91.73 O ANISOU 860 O GLY B 470 10747 11207 12899 522 1168 2433 O ATOM 861 N GLN B 471 27.032 -29.845 22.092 1.00106.99 N ANISOU 861 N GLN B 471 12690 13451 14512 315 1042 2492 N ATOM 862 CA GLN B 471 27.473 -30.850 21.137 1.00117.99 C ANISOU 862 CA GLN B 471 13808 14729 16293 237 1065 2481 C ATOM 863 C GLN B 471 27.424 -30.421 19.670 1.00117.72 C ANISOU 863 C GLN B 471 13902 14505 16319 111 978 2189 C ATOM 864 O GLN B 471 28.119 -31.019 18.846 1.00113.72 O ANISOU 864 O GLN B 471 13252 13941 16016 22 964 2143 O ATOM 865 CB GLN B 471 26.583 -32.088 21.257 1.00124.11 C ANISOU 865 CB GLN B 471 14255 15387 17516 421 1224 2669 C ATOM 866 CG GLN B 471 25.621 -32.249 20.069 1.00122.49 C ANISOU 866 CG GLN B 471 14037 14903 17601 433 1218 2486 C ATOM 867 CD GLN B 471 24.307 -32.906 20.442 1.00120.10 C ANISOU 867 CD GLN B 471 13536 14478 17619 640 1338 2672 C ATOM 868 OE1 GLN B 471 24.247 -33.761 21.329 1.00117.37 O ANISOU 868 OE1 GLN B 471 12920 14206 17469 779 1459 2961 O ATOM 869 NE2 GLN B 471 23.238 -32.505 19.758 1.00117.85 N ANISOU 869 NE2 GLN B 471 13363 14009 17407 666 1308 2535 N ATOM 870 N HIS B 472 26.593 -29.433 19.329 1.00122.31 N ANISOU 870 N HIS B 472 14745 14995 16734 125 938 2011 N ATOM 871 CA HIS B 472 26.276 -29.180 17.916 1.00117.83 C ANISOU 871 CA HIS B 472 14246 14245 16281 55 885 1765 C ATOM 872 C HIS B 472 27.489 -29.350 16.993 1.00114.80 C ANISOU 872 C HIS B 472 13814 13868 15936 -100 807 1659 C ATOM 873 O HIS B 472 28.646 -29.205 17.419 1.00115.67 O ANISOU 873 O HIS B 472 13930 14135 15882 -200 756 1743 O ATOM 874 CB HIS B 472 25.604 -27.813 17.636 1.00109.17 C ANISOU 874 CB HIS B 472 13472 13100 14906 39 836 1583 C ATOM 875 CG HIS B 472 25.596 -26.849 18.782 1.00112.75 C ANISOU 875 CG HIS B 472 14175 13689 14977 67 826 1639 C ATOM 876 ND1 HIS B 472 26.578 -26.806 19.748 1.00116.81 N ANISOU 876 ND1 HIS B 472 14709 14391 15282 16 775 1753 N ATOM 877 CD2 HIS B 472 24.740 -25.841 19.074 1.00112.47 C ANISOU 877 CD2 HIS B 472 14404 13619 14712 141 853 1583 C ATOM 878 CE1 HIS B 472 26.304 -25.839 20.608 1.00113.54 C ANISOU 878 CE1 HIS B 472 14574 14048 14518 63 758 1743 C ATOM 879 NE2 HIS B 472 25.196 -25.236 20.219 1.00110.32 N ANISOU 879 NE2 HIS B 472 14324 13501 14092 146 817 1642 N ATOM 880 N ASN B 473 27.209 -29.695 15.736 1.00105.76 N ANISOU 880 N ASN B 473 12613 12557 15014 -105 798 1494 N ATOM 881 CA ASN B 473 28.241 -29.749 14.715 1.00 97.62 C ANISOU 881 CA ASN B 473 11575 11522 13996 -208 740 1380 C ATOM 882 C ASN B 473 28.188 -28.539 13.798 1.00 90.13 C ANISOU 882 C ASN B 473 10873 10549 12822 -280 646 1152 C ATOM 883 O ASN B 473 27.164 -28.242 13.184 1.00 91.79 O ANISOU 883 O ASN B 473 11161 10642 13072 -230 644 1004 O ATOM 884 CB ASN B 473 28.148 -31.046 13.930 1.00102.31 C ANISOU 884 CB ASN B 473 11939 11961 14975 -145 798 1354 C ATOM 885 CG ASN B 473 29.115 -32.099 14.450 1.00103.72 C ANISOU 885 CG ASN B 473 11879 12211 15321 -143 878 1574 C ATOM 886 OD1 ASN B 473 30.335 -31.923 14.395 1.00 98.05 O ANISOU 886 OD1 ASN B 473 11173 11615 14468 -231 856 1639 O ATOM 887 ND2 ASN B 473 28.575 -33.197 14.961 1.00104.34 N ANISOU 887 ND2 ASN B 473 11719 12211 15716 -40 979 1719 N ATOM 888 N TYR B 474 29.301 -27.817 13.758 1.00 78.13 N ANISOU 888 N TYR B 474 9461 9150 11075 -399 568 1156 N ATOM 889 CA TYR B 474 29.363 -26.513 13.100 1.00 61.08 C ANISOU 889 CA TYR B 474 7530 6993 8684 -472 481 988 C ATOM 890 C TYR B 474 30.118 -26.680 11.812 1.00 46.91 C ANISOU 890 C TYR B 474 5676 5174 6974 -491 459 906 C ATOM 891 O TYR B 474 31.108 -27.452 11.784 1.00 62.26 O ANISOU 891 O TYR B 474 7461 7165 9030 -505 481 1038 O ATOM 892 CB TYR B 474 30.166 -25.554 13.980 1.00 52.43 C ANISOU 892 CB TYR B 474 6587 6039 7296 -597 387 1072 C ATOM 893 CG TYR B 474 29.461 -25.020 15.217 1.00 51.08 C ANISOU 893 CG TYR B 474 6573 5905 6930 -568 392 1111 C ATOM 894 CD1 TYR B 474 28.182 -24.492 15.147 1.00 55.96 C ANISOU 894 CD1 TYR B 474 7336 6424 7501 -478 446 999 C ATOM 895 CD2 TYR B 474 30.120 -24.984 16.436 1.00 59.13 C ANISOU 895 CD2 TYR B 474 7609 7069 7787 -623 341 1271 C ATOM 896 CE1 TYR B 474 27.547 -23.965 16.279 1.00 62.05 C ANISOU 896 CE1 TYR B 474 8279 7227 8070 -417 473 1050 C ATOM 897 CE2 TYR B 474 29.509 -24.473 17.575 1.00 68.80 C ANISOU 897 CE2 TYR B 474 9010 8339 8792 -566 347 1298 C ATOM 898 CZ TYR B 474 28.231 -23.963 17.504 1.00 74.92 C ANISOU 898 CZ TYR B 474 9943 9003 9520 -453 422 1190 C ATOM 899 OH TYR B 474 27.645 -23.447 18.656 1.00 69.63 O ANISOU 899 OH TYR B 474 9470 8378 8611 -364 450 1235 O ATOM 900 N LEU B 475 29.726 -25.950 10.765 1.00 54.56 N ANISOU 900 N LEU B 475 6766 6086 7877 -478 429 717 N ATOM 901 CA LEU B 475 30.464 -26.024 9.491 1.00 53.56 C ANISOU 901 CA LEU B 475 6598 5959 7794 -460 416 647 C ATOM 902 C LEU B 475 30.944 -24.646 9.044 1.00 48.96 C ANISOU 902 C LEU B 475 6170 5445 6989 -535 341 602 C ATOM 903 O LEU B 475 30.166 -23.715 8.962 1.00 45.73 O ANISOU 903 O LEU B 475 5910 5008 6456 -544 325 486 O ATOM 904 CB LEU B 475 29.613 -26.703 8.372 1.00 54.92 C ANISOU 904 CB LEU B 475 6715 5998 8152 -333 456 463 C ATOM 905 CG LEU B 475 30.333 -26.954 6.993 1.00 56.13 C ANISOU 905 CG LEU B 475 6833 6151 8342 -259 459 379 C ATOM 906 CD1 LEU B 475 31.660 -27.778 7.090 1.00 61.83 C ANISOU 906 CD1 LEU B 475 7416 6920 9158 -251 505 561 C ATOM 907 CD2 LEU B 475 29.419 -27.587 5.888 1.00 58.47 C ANISOU 907 CD2 LEU B 475 7111 6317 8787 -133 464 157 C ATOM 908 N CYS B 476 32.238 -24.514 8.721 1.00 40.75 N ANISOU 908 N CYS B 476 5078 4487 5920 -582 305 719 N ATOM 909 CA CYS B 476 32.764 -23.244 8.240 1.00 27.95 C ANISOU 909 CA CYS B 476 3562 2917 4139 -646 230 710 C ATOM 910 C CYS B 476 32.268 -23.139 6.834 1.00 33.32 C ANISOU 910 C CYS B 476 4250 3554 4856 -514 279 537 C ATOM 911 O CYS B 476 32.234 -24.151 6.083 1.00 38.77 O ANISOU 911 O CYS B 476 4836 4206 5690 -386 344 486 O ATOM 912 CB CYS B 476 34.363 -23.242 8.293 1.00 37.04 C ANISOU 912 CB CYS B 476 4610 4170 5295 -725 176 951 C ATOM 913 SG CYS B 476 35.120 -21.728 7.720 1.00 40.71 S ANISOU 913 SG CYS B 476 5152 4683 5632 -806 71 999 S ATOM 914 N ALA B 477 31.945 -21.924 6.421 1.00 30.59 N ANISOU 914 N ALA B 477 4027 3218 4380 -535 249 448 N ATOM 915 CA ALA B 477 31.597 -21.644 5.051 1.00 35.41 C ANISOU 915 CA ALA B 477 4635 3829 4989 -408 290 312 C ATOM 916 C ALA B 477 32.762 -21.064 4.256 1.00 41.90 C ANISOU 916 C ALA B 477 5403 4740 5777 -382 271 429 C ATOM 917 O ALA B 477 32.580 -20.730 3.101 1.00 38.66 O ANISOU 917 O ALA B 477 4984 4360 5343 -257 310 343 O ATOM 918 CB ALA B 477 30.412 -20.580 4.999 1.00 40.44 C ANISOU 918 CB ALA B 477 5418 4430 5517 -425 299 167 C ATOM 919 N GLY B 478 33.952 -20.959 4.810 1.00 41.55 N ANISOU 919 N GLY B 478 5304 4746 5736 -484 212 646 N ATOM 920 CA GLY B 478 35.075 -20.371 4.040 1.00 40.48 C ANISOU 920 CA GLY B 478 5090 4690 5602 -450 194 812 C ATOM 921 C GLY B 478 36.154 -21.419 3.865 1.00 47.20 C ANISOU 921 C GLY B 478 5787 5583 6562 -378 236 1010 C ATOM 922 O GLY B 478 36.027 -22.376 3.072 1.00 42.44 O ANISOU 922 O GLY B 478 5131 4968 6027 -194 338 938 O ATOM 923 N ARG B 479 37.213 -21.268 4.641 1.00 44.39 N ANISOU 923 N ARG B 479 5369 5272 6227 -525 155 1265 N ATOM 924 CA ARG B 479 38.405 -22.102 4.446 1.00 46.77 C ANISOU 924 CA ARG B 479 5504 5628 6637 -460 206 1530 C ATOM 925 C ARG B 479 38.993 -22.589 5.755 1.00 52.00 C ANISOU 925 C ARG B 479 6105 6316 7336 -638 141 1728 C ATOM 926 O ARG B 479 40.159 -22.992 5.776 1.00 42.55 O ANISOU 926 O ARG B 479 4759 5183 6223 -642 155 2026 O ATOM 927 CB ARG B 479 39.458 -21.337 3.620 1.00 43.06 C ANISOU 927 CB ARG B 479 4942 5231 6185 -402 190 1763 C ATOM 928 CG ARG B 479 39.059 -21.094 2.173 1.00 43.43 C ANISOU 928 CG ARG B 479 5005 5294 6202 -159 293 1623 C ATOM 929 CD ARG B 479 40.004 -19.998 1.552 1.00 40.29 C ANISOU 929 CD ARG B 479 4511 4972 5827 -130 254 1880 C ATOM 930 NE ARG B 479 39.690 -19.757 0.154 1.00 41.70 N ANISOU 930 NE ARG B 479 4683 5200 5963 133 367 1782 N ATOM 931 CZ ARG B 479 38.602 -19.142 -0.306 1.00 45.15 C ANISOU 931 CZ ARG B 479 5222 5626 6308 177 379 1510 C ATOM 932 NH1 ARG B 479 37.708 -18.642 0.535 1.00 47.29 N ANISOU 932 NH1 ARG B 479 5621 5819 6526 -26 294 1316 N ATOM 933 NH2 ARG B 479 38.422 -19.027 -1.617 1.00 42.80 N ANISOU 933 NH2 ARG B 479 4896 5406 5962 439 486 1452 N ATOM 934 N ASN B 480 38.171 -22.636 6.813 1.00 42.16 N ANISOU 934 N ASN B 480 4958 5030 6028 -758 91 1583 N ATOM 935 CA ASN B 480 38.590 -23.046 8.164 1.00 48.07 C ANISOU 935 CA ASN B 480 5661 5827 6776 -919 25 1751 C ATOM 936 C ASN B 480 39.670 -22.097 8.674 1.00 48.31 C ANISOU 936 C ASN B 480 5680 5931 6746 -1116 -154 1986 C ATOM 937 O ASN B 480 40.569 -22.509 9.367 1.00 49.65 O ANISOU 937 O ASN B 480 5730 6180 6954 -1221 -204 2247 O ATOM 938 CB ASN B 480 39.128 -24.511 8.233 1.00 37.22 C ANISOU 938 CB ASN B 480 4098 4481 5562 -832 156 1930 C ATOM 939 CG ASN B 480 38.042 -25.543 8.386 1.00 43.81 C ANISOU 939 CG ASN B 480 4936 5232 6479 -723 275 1731 C ATOM 940 OD1 ASN B 480 38.226 -26.708 7.999 1.00 45.92 O ANISOU 940 OD1 ASN B 480 5076 5465 6905 -592 413 1783 O ATOM 941 ND2 ASN B 480 36.941 -25.161 9.043 1.00 38.27 N ANISOU 941 ND2 ASN B 480 4369 4486 5685 -779 226 1534 N ATOM 942 N ASP B 481 39.581 -20.836 8.299 1.00 41.34 N ANISOU 942 N ASP B 481 4907 5014 5787 -1169 -251 1905 N ATOM 943 CA ASP B 481 40.470 -19.823 8.866 1.00 47.09 C ANISOU 943 CA ASP B 481 5649 5772 6472 -1384 -460 2090 C ATOM 944 C ASP B 481 39.833 -18.439 8.880 1.00 49.28 C ANISOU 944 C ASP B 481 6128 5962 6633 -1465 -564 1877 C ATOM 945 O ASP B 481 40.453 -17.454 8.451 1.00 45.75 O ANISOU 945 O ASP B 481 5657 5497 6230 -1532 -669 1988 O ATOM 946 CB ASP B 481 41.751 -19.790 8.042 1.00 53.52 C ANISOU 946 CB ASP B 481 6261 6642 7433 -1342 -460 2414 C ATOM 947 CG ASP B 481 41.555 -19.200 6.686 1.00 79.71 C ANISOU 947 CG ASP B 481 9572 9924 10791 -1168 -373 2338 C ATOM 948 OD1 ASP B 481 40.378 -18.974 6.320 1.00 81.38 O ANISOU 948 OD1 ASP B 481 9925 10074 10923 -1074 -297 2021 O ATOM 949 OD2 ASP B 481 42.580 -18.944 5.992 1.00 92.62 O ANISOU 949 OD2 ASP B 481 11047 11603 12541 -1118 -380 2624 O ATOM 950 N CYS B 482 38.602 -18.345 9.376 1.00 48.16 N ANISOU 950 N CYS B 482 6175 5759 6363 -1452 -526 1597 N ATOM 951 CA CYS B 482 37.900 -17.088 9.360 1.00 44.43 C ANISOU 951 CA CYS B 482 5905 5193 5783 -1501 -581 1393 C ATOM 952 C CYS B 482 38.545 -16.112 10.316 1.00 47.12 C ANISOU 952 C CYS B 482 6359 5509 6037 -1742 -819 1470 C ATOM 953 O CYS B 482 39.201 -16.523 11.275 1.00 52.71 O ANISOU 953 O CYS B 482 7035 6284 6709 -1874 -941 1620 O ATOM 954 CB CYS B 482 36.426 -17.311 9.777 1.00 52.55 C ANISOU 954 CB CYS B 482 7107 6165 6697 -1417 -468 1123 C ATOM 955 SG CYS B 482 35.471 -18.266 8.502 1.00 45.77 S ANISOU 955 SG CYS B 482 6141 5296 5952 -1149 -228 979 S ATOM 956 N ILE B 483 38.364 -14.817 10.058 1.00 44.31 N ANISOU 956 N ILE B 483 6130 5054 5651 -1804 -891 1370 N ATOM 957 CA ILE B 483 38.747 -13.750 11.019 1.00 46.21 C ANISOU 957 CA ILE B 483 6548 5220 5791 -2038 -1134 1361 C ATOM 958 C ILE B 483 37.790 -13.784 12.187 1.00 49.93 C ANISOU 958 C ILE B 483 7284 5656 6029 -2058 -1133 1138 C ATOM 959 O ILE B 483 36.600 -13.758 11.997 1.00 53.54 O ANISOU 959 O ILE B 483 7864 6063 6418 -1916 -961 931 O ATOM 960 CB ILE B 483 38.594 -12.376 10.359 1.00 53.64 C ANISOU 960 CB ILE B 483 7565 6034 6782 -2062 -1163 1278 C ATOM 961 CG1 ILE B 483 39.677 -12.182 9.295 1.00 60.94 C ANISOU 961 CG1 ILE B 483 8216 6995 7943 -2045 -1191 1554 C ATOM 962 CG2 ILE B 483 38.670 -11.250 11.394 1.00 61.42 C ANISOU 962 CG2 ILE B 483 8808 6891 7639 -2284 -1392 1175 C ATOM 963 CD1 ILE B 483 39.209 -11.376 8.059 1.00 62.79 C ANISOU 963 CD1 ILE B 483 8409 7174 8274 -1899 -1048 1485 C ATOM 964 N ILE B 484 38.280 -13.886 13.408 1.00 50.84 N ANISOU 964 N ILE B 484 7484 5815 6020 -2217 -1317 1199 N ATOM 965 CA ILE B 484 37.372 -13.859 14.554 1.00 49.63 C ANISOU 965 CA ILE B 484 7600 5639 5617 -2201 -1309 1001 C ATOM 966 C ILE B 484 37.604 -12.575 15.359 1.00 73.39 C ANISOU 966 C ILE B 484 10889 8534 8460 -2396 -1555 893 C ATOM 967 O ILE B 484 38.587 -12.485 16.077 1.00 72.38 O ANISOU 967 O ILE B 484 10754 8455 8291 -2589 -1805 1024 O ATOM 968 CB ILE B 484 37.537 -15.107 15.444 1.00 69.47 C ANISOU 968 CB ILE B 484 10017 8309 8069 -2177 -1294 1125 C ATOM 969 CG1 ILE B 484 37.269 -16.377 14.625 1.00 76.43 C ANISOU 969 CG1 ILE B 484 10636 9262 9141 -1983 -1050 1207 C ATOM 970 CG2 ILE B 484 36.592 -15.031 16.645 1.00 66.86 C ANISOU 970 CG2 ILE B 484 9964 7969 7470 -2124 -1275 947 C ATOM 971 CD1 ILE B 484 35.816 -16.538 14.117 1.00 58.06 C ANISOU 971 CD1 ILE B 484 8389 6857 6814 -1770 -811 990 C ATOM 972 N ASP B 485 36.733 -11.572 15.213 1.00 62.88 N ANISOU 972 N ASP B 485 9801 7047 7046 -2351 -1492 664 N ATOM 973 CA ASP B 485 36.882 -10.341 15.997 1.00 76.32 C ANISOU 973 CA ASP B 485 11808 8605 8584 -2523 -1716 526 C ATOM 974 C ASP B 485 35.549 -9.941 16.614 1.00 77.35 C ANISOU 974 C ASP B 485 12284 8640 8464 -2386 -1570 265 C ATOM 975 O ASP B 485 34.560 -10.629 16.436 1.00 71.48 O ANISOU 975 O ASP B 485 11510 7951 7699 -2174 -1313 225 O ATOM 976 CB ASP B 485 37.464 -9.207 15.143 1.00 80.21 C ANISOU 976 CB ASP B 485 12243 8953 9279 -2647 -1827 560 C ATOM 977 CG ASP B 485 36.466 -8.657 14.115 1.00 84.69 C ANISOU 977 CG ASP B 485 12833 9416 9930 -2475 -1567 426 C ATOM 978 OD1 ASP B 485 35.252 -8.829 14.299 1.00 82.72 O ANISOU 978 OD1 ASP B 485 12747 9153 9529 -2305 -1353 256 O ATOM 979 OD2 ASP B 485 36.894 -8.036 13.122 1.00 85.17 O ANISOU 979 OD2 ASP B 485 12731 9417 10214 -2504 -1574 515 O ATOM 980 N LYS B 486 35.527 -8.837 17.348 1.00 93.63 N ANISOU 980 N LYS B 486 14678 10552 10346 -2501 -1738 99 N ATOM 981 CA LYS B 486 34.353 -8.450 18.123 1.00101.37 C ANISOU 981 CA LYS B 486 16028 11444 11044 -2360 -1609 -126 C ATOM 982 C LYS B 486 33.089 -8.525 17.300 1.00 94.42 C ANISOU 982 C LYS B 486 15114 10522 10237 -2125 -1259 -187 C ATOM 983 O LYS B 486 32.040 -8.962 17.763 1.00 85.76 O ANISOU 983 O LYS B 486 14143 9459 8985 -1928 -1060 -244 O ATOM 984 CB LYS B 486 34.523 -7.029 18.657 1.00117.41 C ANISOU 984 CB LYS B 486 18418 13258 12936 -2513 -1815 -315 C ATOM 985 CG LYS B 486 33.218 -6.239 18.781 1.00119.40 C ANISOU 985 CG LYS B 486 19009 13337 13021 -2339 -1588 -538 C ATOM 986 CD LYS B 486 32.311 -6.774 19.878 1.00116.20 C ANISOU 986 CD LYS B 486 18852 13009 12289 -2134 -1452 -613 C ATOM 987 CE LYS B 486 31.420 -5.670 20.446 1.00114.56 C ANISOU 987 CE LYS B 486 19110 12588 11829 -2035 -1361 -846 C ATOM 988 NZ LYS B 486 30.694 -6.104 21.681 1.00113.13 N ANISOU 988 NZ LYS B 486 19209 12488 11289 -1828 -1269 -898 N ATOM 989 N ILE B 487 33.190 -8.087 16.063 1.00106.29 N ANISOU 989 N ILE B 487 16435 11962 11988 -2139 -1188 -152 N ATOM 990 CA ILE B 487 32.017 -7.975 15.230 1.00108.65 C ANISOU 990 CA ILE B 487 16712 12218 12354 -1941 -883 -213 C ATOM 991 C ILE B 487 31.784 -9.248 14.401 1.00 94.27 C ANISOU 991 C ILE B 487 14551 10564 10704 -1796 -710 -81 C ATOM 992 O ILE B 487 30.638 -9.661 14.203 1.00 83.73 O ANISOU 992 O ILE B 487 13223 9244 9346 -1606 -474 -121 O ATOM 993 CB ILE B 487 32.140 -6.734 14.334 1.00114.60 C ANISOU 993 CB ILE B 487 17462 12815 13265 -2009 -878 -254 C ATOM 994 CG1 ILE B 487 30.778 -6.067 14.169 1.00106.80 C ANISOU 994 CG1 ILE B 487 16684 11706 12190 -1844 -612 -394 C ATOM 995 CG2 ILE B 487 32.800 -7.085 13.022 1.00119.09 C ANISOU 995 CG2 ILE B 487 17636 13484 14127 -2015 -862 -79 C ATOM 996 CD1 ILE B 487 30.364 -5.262 15.401 1.00109.10 C ANISOU 996 CD1 ILE B 487 17421 11834 12199 -1862 -660 -570 C ATOM 997 N ARG B 488 32.860 -9.904 13.973 1.00 78.95 N ANISOU 997 N ARG B 488 12324 8741 8934 -1882 -831 86 N ATOM 998 CA ARG B 488 32.742 -11.055 13.072 1.00 68.52 C ANISOU 998 CA ARG B 488 10693 7552 7789 -1745 -677 195 C ATOM 999 C ARG B 488 32.646 -12.406 13.781 1.00 70.58 C ANISOU 999 C ARG B 488 10876 7942 8000 -1677 -648 267 C ATOM 1000 O ARG B 488 32.403 -13.420 13.129 1.00 57.89 O ANISOU 1000 O ARG B 488 9045 6415 6536 -1551 -510 328 O ATOM 1001 CB ARG B 488 33.921 -11.047 12.111 1.00 63.87 C ANISOU 1001 CB ARG B 488 9829 7014 7424 -1828 -777 361 C ATOM 1002 CG ARG B 488 33.806 -9.900 11.108 1.00 64.28 C ANISOU 1002 CG ARG B 488 9871 6965 7587 -1820 -725 320 C ATOM 1003 CD ARG B 488 34.794 -10.039 10.003 1.00 68.27 C ANISOU 1003 CD ARG B 488 10069 7547 8324 -1821 -759 515 C ATOM 1004 NE ARG B 488 36.028 -9.405 10.383 1.00 74.94 N ANISOU 1004 NE ARG B 488 10896 8343 9234 -2035 -1018 651 N ATOM 1005 CZ ARG B 488 36.502 -8.285 9.858 1.00 84.14 C ANISOU 1005 CZ ARG B 488 12022 9410 10540 -2114 -1097 710 C ATOM 1006 NH1 ARG B 488 35.866 -7.673 8.864 1.00 71.17 N ANISOU 1006 NH1 ARG B 488 10335 7728 8978 -1980 -913 651 N ATOM 1007 NH2 ARG B 488 37.650 -7.794 10.314 1.00 89.55 N ANISOU 1007 NH2 ARG B 488 12682 10039 11304 -2331 -1370 854 N ATOM 1008 N ARG B 489 32.848 -12.397 15.104 1.00 59.93 N ANISOU 1008 N ARG B 489 9712 6609 6451 -1755 -781 258 N ATOM 1009 CA ARG B 489 32.683 -13.553 16.008 1.00 68.83 C ANISOU 1009 CA ARG B 489 10793 7862 7497 -1678 -747 336 C ATOM 1010 C ARG B 489 31.515 -14.437 15.695 1.00 59.73 C ANISOU 1010 C ARG B 489 9543 6729 6422 -1455 -491 324 C ATOM 1011 O ARG B 489 31.618 -15.660 15.619 1.00 65.91 O ANISOU 1011 O ARG B 489 10091 7615 7338 -1387 -428 445 O ATOM 1012 CB ARG B 489 32.383 -13.024 17.430 1.00 75.96 C ANISOU 1012 CB ARG B 489 12037 8736 8091 -1695 -835 239 C ATOM 1013 CG ARG B 489 33.502 -13.032 18.393 1.00 88.14 C ANISOU 1013 CG ARG B 489 13618 10365 9506 -1876 -1101 320 C ATOM 1014 CD ARG B 489 33.301 -11.972 19.497 1.00 94.11 C ANISOU 1014 CD ARG B 489 14792 11026 9941 -1928 -1240 147 C ATOM 1015 NE ARG B 489 31.900 -11.700 19.863 1.00 94.01 N ANISOU 1015 NE ARG B 489 15041 10928 9751 -1706 -1017 2 N ATOM 1016 CZ ARG B 489 31.555 -10.709 20.691 1.00 91.03 C ANISOU 1016 CZ ARG B 489 15067 10434 9088 -1700 -1081 -171 C ATOM 1017 NH1 ARG B 489 32.497 -9.925 21.195 1.00 67.94 N ANISOU 1017 NH1 ARG B 489 12320 7456 6040 -1922 -1384 -245 N ATOM 1018 NH2 ARG B 489 30.286 -10.483 21.021 1.00 88.77 N ANISOU 1018 NH2 ARG B 489 15014 10073 8641 -1472 -851 -261 N ATOM 1019 N LYS B 490 30.370 -13.793 15.587 1.00 72.15 N ANISOU 1019 N LYS B 490 11309 8191 7916 -1342 -347 189 N ATOM 1020 CA LYS B 490 29.082 -14.454 15.431 1.00 71.44 C ANISOU 1020 CA LYS B 490 11170 8093 7881 -1133 -117 185 C ATOM 1021 C LYS B 490 28.906 -15.163 14.065 1.00 63.32 C ANISOU 1021 C LYS B 490 9849 7086 7126 -1065 -10 214 C ATOM 1022 O LYS B 490 28.065 -16.043 13.916 1.00 68.40 O ANISOU 1022 O LYS B 490 10372 7738 7877 -920 131 244 O ATOM 1023 CB LYS B 490 28.024 -13.367 15.599 1.00 84.13 C ANISOU 1023 CB LYS B 490 13070 9567 9330 -1052 0 60 C ATOM 1024 CG LYS B 490 26.582 -13.838 15.684 1.00 89.93 C ANISOU 1024 CG LYS B 490 13812 10276 10082 -833 232 88 C ATOM 1025 CD LYS B 490 25.799 -12.838 16.522 1.00 88.92 C ANISOU 1025 CD LYS B 490 14049 10042 9695 -750 315 18 C ATOM 1026 CE LYS B 490 24.469 -12.475 15.887 1.00 87.75 C ANISOU 1026 CE LYS B 490 13932 9800 9609 -600 549 12 C ATOM 1027 NZ LYS B 490 23.986 -11.153 16.418 1.00 91.09 N ANISOU 1027 NZ LYS B 490 14730 10088 9792 -564 621 -80 N ATOM 1028 N ASN B 491 29.700 -14.768 13.075 1.00 53.80 N ANISOU 1028 N ASN B 491 8529 5882 6031 -1161 -85 210 N ATOM 1029 CA ASN B 491 29.636 -15.344 11.729 1.00 51.66 C ANISOU 1029 CA ASN B 491 8011 5641 5976 -1082 1 220 C ATOM 1030 C ASN B 491 30.075 -16.793 11.645 1.00 54.67 C ANISOU 1030 C ASN B 491 8147 6113 6513 -1040 3 330 C ATOM 1031 O ASN B 491 29.455 -17.572 10.937 1.00 53.50 O ANISOU 1031 O ASN B 491 7858 5960 6511 -915 116 303 O ATOM 1032 CB ASN B 491 30.537 -14.576 10.776 1.00 54.15 C ANISOU 1032 CB ASN B 491 8255 5959 6359 -1170 -80 233 C ATOM 1033 CG ASN B 491 29.959 -13.248 10.388 1.00 62.90 C ANISOU 1033 CG ASN B 491 9526 6970 7402 -1170 -25 125 C ATOM 1034 OD1 ASN B 491 29.076 -12.715 11.065 1.00 67.54 O ANISOU 1034 OD1 ASN B 491 10339 7475 7846 -1142 42 42 O ATOM 1035 ND2 ASN B 491 30.427 -12.716 9.275 1.00 53.82 N ANISOU 1035 ND2 ASN B 491 8255 5834 6362 -1177 -29 146 N ATOM 1036 N CYS B 492 31.150 -17.183 12.324 1.00 47.87 N ANISOU 1036 N CYS B 492 7225 5328 5636 -1146 -123 458 N ATOM 1037 CA CYS B 492 31.595 -18.580 12.140 1.00 40.05 C ANISOU 1037 CA CYS B 492 5981 4415 4822 -1095 -89 580 C ATOM 1038 C CYS B 492 31.868 -19.302 13.417 1.00 47.49 C ANISOU 1038 C CYS B 492 6898 5432 5713 -1124 -126 707 C ATOM 1039 O CYS B 492 33.021 -19.330 13.877 1.00 45.43 O ANISOU 1039 O CYS B 492 6585 5257 5421 -1254 -258 847 O ATOM 1040 CB CYS B 492 32.909 -18.634 11.300 1.00 39.61 C ANISOU 1040 CB CYS B 492 5752 4417 4882 -1163 -166 695 C ATOM 1041 SG CYS B 492 33.186 -20.345 10.729 1.00 41.98 S ANISOU 1041 SG CYS B 492 5764 4767 5418 -1037 -56 799 S ATOM 1042 N PRO B 493 30.844 -19.916 14.000 1.00 42.49 N ANISOU 1042 N PRO B 493 6277 4781 5087 -999 -12 692 N ATOM 1043 CA PRO B 493 31.055 -20.594 15.260 1.00 41.61 C ANISOU 1043 CA PRO B 493 6127 4762 4921 -997 -29 834 C ATOM 1044 C PRO B 493 31.994 -21.785 15.075 1.00 60.13 C ANISOU 1044 C PRO B 493 8185 7195 7468 -1016 -26 1008 C ATOM 1045 O PRO B 493 32.613 -22.198 16.048 1.00 47.61 O ANISOU 1045 O PRO B 493 6538 5724 5826 -1069 -80 1168 O ATOM 1046 CB PRO B 493 29.636 -21.073 15.657 1.00 45.02 C ANISOU 1046 CB PRO B 493 6578 5136 5390 -814 132 810 C ATOM 1047 CG PRO B 493 28.841 -21.038 14.312 1.00 47.05 C ANISOU 1047 CG PRO B 493 6789 5275 5815 -736 226 673 C ATOM 1048 CD PRO B 493 29.401 -19.863 13.628 1.00 50.26 C ANISOU 1048 CD PRO B 493 7324 5662 6110 -852 133 570 C ATOM 1049 N ALA B 494 32.102 -22.362 13.880 1.00 44.81 N ANISOU 1049 N ALA B 494 6071 5207 5746 -962 44 986 N ATOM 1050 CA ALA B 494 33.134 -23.415 13.729 1.00 45.01 C ANISOU 1050 CA ALA B 494 5847 5309 5946 -979 55 1170 C ATOM 1051 C ALA B 494 34.505 -22.839 14.007 1.00 49.18 C ANISOU 1051 C ALA B 494 6383 5941 6363 -1153 -102 1318 C ATOM 1052 O ALA B 494 35.311 -23.433 14.747 1.00 46.45 O ANISOU 1052 O ALA B 494 5904 5712 6032 -1216 -136 1530 O ATOM 1053 CB ALA B 494 33.129 -23.968 12.331 1.00 41.82 C ANISOU 1053 CB ALA B 494 5309 4830 5750 -883 142 1103 C ATOM 1054 N CYS B 495 34.815 -21.716 13.368 1.00 42.96 N ANISOU 1054 N CYS B 495 5717 5115 5492 -1233 -198 1237 N ATOM 1055 CA CYS B 495 36.184 -21.171 13.482 1.00 49.23 C ANISOU 1055 CA CYS B 495 6481 5987 6239 -1406 -366 1410 C ATOM 1056 C CYS B 495 36.403 -20.594 14.866 1.00 58.46 C ANISOU 1056 C CYS B 495 7807 7220 7187 -1555 -533 1449 C ATOM 1057 O CYS B 495 37.503 -20.679 15.420 1.00 53.68 O ANISOU 1057 O CYS B 495 7114 6723 6559 -1697 -669 1659 O ATOM 1058 CB CYS B 495 36.469 -20.129 12.420 1.00 43.02 C ANISOU 1058 CB CYS B 495 5752 5133 5461 -1439 -423 1343 C ATOM 1059 SG CYS B 495 36.970 -20.856 10.825 1.00 48.42 S ANISOU 1059 SG CYS B 495 6198 5818 6382 -1288 -285 1426 S ATOM 1060 N ARG B 496 35.353 -20.005 15.428 1.00 50.33 N ANISOU 1060 N ARG B 496 7016 6125 5982 -1515 -523 1256 N ATOM 1061 CA ARG B 496 35.421 -19.487 16.786 1.00 53.33 C ANISOU 1061 CA ARG B 496 7592 6562 6110 -1614 -667 1256 C ATOM 1062 C ARG B 496 35.705 -20.603 17.763 1.00 57.01 C ANISOU 1062 C ARG B 496 7898 7183 6579 -1586 -639 1451 C ATOM 1063 O ARG B 496 36.530 -20.469 18.658 1.00 59.50 O ANISOU 1063 O ARG B 496 8230 7619 6758 -1726 -810 1584 O ATOM 1064 CB ARG B 496 34.124 -18.767 17.152 1.00 52.05 C ANISOU 1064 CB ARG B 496 7717 6293 5765 -1515 -603 1028 C ATOM 1065 CG ARG B 496 34.201 -17.979 18.467 1.00 59.28 C ANISOU 1065 CG ARG B 496 8914 7240 6370 -1604 -769 979 C ATOM 1066 CD ARG B 496 32.836 -17.326 18.759 1.00 58.48 C ANISOU 1066 CD ARG B 496 9102 7021 6098 -1458 -651 775 C ATOM 1067 NE ARG B 496 32.933 -16.293 19.784 1.00 69.12 N ANISOU 1067 NE ARG B 496 10786 8347 7128 -1542 -818 671 N ATOM 1068 CZ ARG B 496 31.890 -15.679 20.338 1.00 70.31 C ANISOU 1068 CZ ARG B 496 11239 8413 7063 -1411 -732 522 C ATOM 1069 NH1 ARG B 496 30.661 -15.998 19.983 1.00 62.91 N ANISOU 1069 NH1 ARG B 496 10281 7413 6210 -1200 -482 493 N ATOM 1070 NH2 ARG B 496 32.074 -14.742 21.268 1.00 70.46 N ANISOU 1070 NH2 ARG B 496 11590 8403 6780 -1487 -900 411 N ATOM 1071 N TYR B 497 35.014 -21.722 17.594 1.00 52.72 N ANISOU 1071 N TYR B 497 7187 6639 6207 -1407 -429 1480 N ATOM 1072 CA TYR B 497 35.112 -22.797 18.539 1.00 44.58 C ANISOU 1072 CA TYR B 497 5988 5746 5205 -1347 -364 1671 C ATOM 1073 C TYR B 497 36.448 -23.460 18.392 1.00 62.29 C ANISOU 1073 C TYR B 497 7968 8106 7593 -1456 -410 1927 C ATOM 1074 O TYR B 497 37.060 -23.830 19.373 1.00 63.94 O ANISOU 1074 O TYR B 497 8090 8479 7723 -1519 -475 2125 O ATOM 1075 CB TYR B 497 33.997 -23.818 18.305 1.00 47.99 C ANISOU 1075 CB TYR B 497 6283 6109 5842 -1127 -129 1644 C ATOM 1076 CG TYR B 497 34.051 -25.031 19.208 1.00 64.82 C ANISOU 1076 CG TYR B 497 8187 8372 8070 -1039 -26 1869 C ATOM 1077 CD1 TYR B 497 33.996 -24.911 20.590 1.00 75.13 C ANISOU 1077 CD1 TYR B 497 9580 9824 9142 -1024 -78 1962 C ATOM 1078 CD2 TYR B 497 34.126 -26.302 18.671 1.00 82.75 C ANISOU 1078 CD2 TYR B 497 10159 10616 10666 -952 131 1987 C ATOM 1079 CE1 TYR B 497 34.031 -26.030 21.408 1.00 78.39 C ANISOU 1079 CE1 TYR B 497 9752 10376 9655 -922 35 2196 C ATOM 1080 CE2 TYR B 497 34.159 -27.416 19.473 1.00 95.01 C ANISOU 1080 CE2 TYR B 497 11477 12278 12344 -864 244 2210 C ATOM 1081 CZ TYR B 497 34.112 -27.281 20.838 1.00 91.09 C ANISOU 1081 CZ TYR B 497 11038 11948 11625 -847 202 2328 C ATOM 1082 OH TYR B 497 34.141 -28.421 21.609 1.00 96.01 O ANISOU 1082 OH TYR B 497 11390 12695 12393 -739 335 2578 O ATOM 1083 N ARG B 498 36.909 -23.605 17.159 1.00 51.92 N ANISOU 1083 N ARG B 498 6526 6719 6481 -1463 -368 1942 N ATOM 1084 CA ARG B 498 38.236 -24.170 16.931 1.00 56.45 C ANISOU 1084 CA ARG B 498 6856 7393 7197 -1552 -394 2220 C ATOM 1085 C ARG B 498 39.332 -23.391 17.655 1.00 70.80 C ANISOU 1085 C ARG B 498 8733 9332 8834 -1782 -649 2376 C ATOM 1086 O ARG B 498 40.196 -23.980 18.293 1.00 70.05 O ANISOU 1086 O ARG B 498 8456 9396 8762 -1860 -687 2652 O ATOM 1087 CB ARG B 498 38.544 -24.199 15.446 1.00 57.36 C ANISOU 1087 CB ARG B 498 6885 7403 7504 -1501 -321 2196 C ATOM 1088 CG ARG B 498 40.001 -24.567 15.130 1.00 61.32 C ANISOU 1088 CG ARG B 498 7163 7999 8135 -1586 -351 2515 C ATOM 1089 CD ARG B 498 40.216 -24.576 13.637 1.00 66.88 C ANISOU 1089 CD ARG B 498 7809 8602 9001 -1481 -256 2484 C ATOM 1090 NE ARG B 498 39.791 -23.300 13.078 1.00 66.15 N ANISOU 1090 NE ARG B 498 7929 8412 8793 -1511 -359 2257 N ATOM 1091 CZ ARG B 498 40.513 -22.179 13.137 1.00 83.35 C ANISOU 1091 CZ ARG B 498 10182 10608 10880 -1680 -561 2334 C ATOM 1092 NH1 ARG B 498 41.708 -22.166 13.724 1.00 92.53 N ANISOU 1092 NH1 ARG B 498 11225 11886 12045 -1847 -705 2636 N ATOM 1093 NH2 ARG B 498 40.045 -21.060 12.610 1.00 75.85 N ANISOU 1093 NH2 ARG B 498 9411 9555 9853 -1690 -626 2125 N ATOM 1094 N LYS B 499 39.338 -22.072 17.544 1.00 55.20 N ANISOU 1094 N LYS B 499 6996 7278 6699 -1900 -832 2218 N ATOM 1095 CA LYS B 499 40.383 -21.328 18.226 1.00 69.60 C ANISOU 1095 CA LYS B 499 8877 9191 8376 -2138 -1111 2358 C ATOM 1096 C LYS B 499 40.166 -21.139 19.735 1.00 78.70 C ANISOU 1096 C LYS B 499 10200 10458 9244 -2199 -1247 2325 C ATOM 1097 O LYS B 499 41.084 -20.708 20.433 1.00 77.69 O ANISOU 1097 O LYS B 499 10098 10434 8989 -2404 -1498 2464 O ATOM 1098 CB LYS B 499 40.630 -19.997 17.550 1.00 74.17 C ANISOU 1098 CB LYS B 499 9618 9631 8931 -2260 -1278 2236 C ATOM 1099 CG LYS B 499 39.477 -19.057 17.520 1.00 70.28 C ANISOU 1099 CG LYS B 499 9436 8986 8279 -2199 -1269 1890 C ATOM 1100 CD LYS B 499 39.881 -17.794 16.747 1.00 84.29 C ANISOU 1100 CD LYS B 499 11307 10626 10092 -2322 -1419 1825 C ATOM 1101 CE LYS B 499 40.403 -18.106 15.333 1.00 93.44 C ANISOU 1101 CE LYS B 499 12213 11761 11530 -2250 -1299 1973 C ATOM 1102 NZ LYS B 499 41.091 -16.934 14.697 1.00 97.05 N ANISOU 1102 NZ LYS B 499 12690 12127 12059 -2385 -1471 2019 N ATOM 1103 N CYS B 500 38.977 -21.453 20.245 1.00 73.89 N ANISOU 1103 N CYS B 500 9705 9837 8531 -2017 -1093 2160 N ATOM 1104 CA CYS B 500 38.814 -21.585 21.684 1.00 76.18 C ANISOU 1104 CA CYS B 500 10094 10283 8570 -2008 -1163 2197 C ATOM 1105 C CYS B 500 39.667 -22.773 22.093 1.00 85.17 C ANISOU 1105 C CYS B 500 10888 11631 9842 -2029 -1113 2546 C ATOM 1106 O CYS B 500 40.521 -22.673 22.972 1.00 87.69 O ANISOU 1106 O CYS B 500 11186 12124 10007 -2186 -1313 2722 O ATOM 1107 CB CYS B 500 37.350 -21.847 22.075 1.00 76.25 C ANISOU 1107 CB CYS B 500 10232 10243 8496 -1759 -955 2023 C ATOM 1108 SG CYS B 500 36.260 -20.380 22.159 1.00 67.77 S ANISOU 1108 SG CYS B 500 9625 8976 7147 -1717 -1015 1651 S ATOM 1109 N LEU B 501 39.423 -23.906 21.441 1.00 72.80 N ANISOU 1109 N LEU B 501 9053 10041 8567 -1871 -848 2647 N ATOM 1110 CA LEU B 501 40.157 -25.127 21.724 1.00 81.14 C ANISOU 1110 CA LEU B 501 9761 11268 9799 -1860 -743 2987 C ATOM 1111 C LEU B 501 41.664 -24.902 21.649 1.00 89.01 C ANISOU 1111 C LEU B 501 10626 12373 10820 -2096 -939 3256 C ATOM 1112 O LEU B 501 42.413 -25.370 22.496 1.00 95.95 O ANISOU 1112 O LEU B 501 11337 13467 11652 -2181 -1001 3538 O ATOM 1113 CB LEU B 501 39.741 -26.222 20.744 1.00 74.12 C ANISOU 1113 CB LEU B 501 8639 10265 9257 -1673 -448 3009 C ATOM 1114 CG LEU B 501 38.588 -27.096 21.214 1.00 75.19 C ANISOU 1114 CG LEU B 501 8706 10393 9471 -1444 -226 2962 C ATOM 1115 CD1 LEU B 501 37.648 -26.283 22.045 1.00 85.56 C ANISOU 1115 CD1 LEU B 501 10321 11705 10482 -1394 -310 2752 C ATOM 1116 CD2 LEU B 501 37.841 -27.713 20.039 1.00 64.53 C ANISOU 1116 CD2 LEU B 501 7269 8830 8418 -1279 -10 2822 C ATOM 1117 N GLN B 502 42.099 -24.173 20.638 1.00 75.00 N ANISOU 1117 N GLN B 502 8912 10458 9125 -2196 -1035 3196 N ATOM 1118 CA GLN B 502 43.513 -24.014 20.373 1.00 94.12 C ANISOU 1118 CA GLN B 502 11167 12954 11641 -2393 -1191 3499 C ATOM 1119 C GLN B 502 44.155 -22.923 21.224 1.00 99.19 C ANISOU 1119 C GLN B 502 11986 13672 12028 -2654 -1562 3520 C ATOM 1120 O GLN B 502 45.371 -22.777 21.229 1.00102.24 O ANISOU 1120 O GLN B 502 12220 14145 12481 -2850 -1739 3817 O ATOM 1121 CB GLN B 502 43.726 -23.702 18.890 1.00 96.08 C ANISOU 1121 CB GLN B 502 11383 13023 12101 -2359 -1126 3461 C ATOM 1122 CG GLN B 502 43.382 -24.862 18.004 1.00 85.58 C ANISOU 1122 CG GLN B 502 9853 11631 11031 -2127 -796 3491 C ATOM 1123 CD GLN B 502 43.382 -24.518 16.528 1.00 72.07 C ANISOU 1123 CD GLN B 502 8160 9749 9473 -2042 -720 3390 C ATOM 1124 OE1 GLN B 502 43.472 -23.344 16.117 1.00 72.64 O ANISOU 1124 OE1 GLN B 502 8398 9733 9469 -2137 -891 3270 O ATOM 1125 NE2 GLN B 502 43.275 -25.552 15.712 1.00 66.09 N ANISOU 1125 NE2 GLN B 502 7232 8942 8938 -1847 -458 3439 N ATOM 1126 N ALA B 503 43.347 -22.128 21.906 1.00 84.30 N ANISOU 1126 N ALA B 503 10430 11739 9861 -2657 -1687 3210 N ATOM 1127 CA ALA B 503 43.902 -21.163 22.834 1.00 89.61 C ANISOU 1127 CA ALA B 503 11303 12479 10267 -2895 -2052 3196 C ATOM 1128 C ALA B 503 43.981 -21.829 24.206 1.00 93.20 C ANISOU 1128 C ALA B 503 11699 13195 10517 -2881 -2081 3345 C ATOM 1129 O ALA B 503 44.477 -21.237 25.159 1.00 82.77 O ANISOU 1129 O ALA B 503 10524 11986 8939 -3066 -2388 3363 O ATOM 1130 CB ALA B 503 43.071 -19.904 22.883 1.00 83.75 C ANISOU 1130 CB ALA B 503 10972 11543 9306 -2901 -2179 2790 C ATOM 1131 N GLY B 504 43.483 -23.062 24.285 1.00100.60 N ANISOU 1131 N GLY B 504 12419 14228 11578 -2656 -1763 3453 N ATOM 1132 CA GLY B 504 43.635 -23.886 25.464 1.00 98.51 C ANISOU 1132 CA GLY B 504 12000 14236 11192 -2611 -1728 3675 C ATOM 1133 C GLY B 504 42.368 -24.059 26.277 1.00 90.17 C ANISOU 1133 C GLY B 504 11125 13215 9922 -2370 -1587 3462 C ATOM 1134 O GLY B 504 42.392 -24.692 27.340 1.00 73.82 O ANISOU 1134 O GLY B 504 8941 11388 7718 -2295 -1550 3639 O ATOM 1135 N MET B 505 41.251 -23.514 25.805 1.00 73.39 N ANISOU 1135 N MET B 505 9262 10862 7763 -2231 -1494 3116 N ATOM 1136 CA MET B 505 40.032 -23.563 26.603 1.00 68.36 C ANISOU 1136 CA MET B 505 8818 10248 6908 -1992 -1368 2941 C ATOM 1137 C MET B 505 39.622 -25.007 26.850 1.00 72.55 C ANISOU 1137 C MET B 505 9009 10909 7650 -1759 -1050 3172 C ATOM 1138 O MET B 505 39.812 -25.882 26.012 1.00 78.69 O ANISOU 1138 O MET B 505 9479 11629 8792 -1723 -853 3322 O ATOM 1139 CB MET B 505 38.898 -22.763 25.957 1.00 75.77 C ANISOU 1139 CB MET B 505 10063 10910 7817 -1881 -1296 2575 C ATOM 1140 CG MET B 505 39.158 -21.251 25.957 1.00 81.18 C ANISOU 1140 CG MET B 505 11127 11466 8251 -2083 -1604 2328 C ATOM 1141 SD MET B 505 37.728 -20.260 25.416 1.00 78.86 S ANISOU 1141 SD MET B 505 11216 10876 7872 -1926 -1492 1920 S ATOM 1142 CE MET B 505 36.695 -20.366 26.892 1.00 63.72 C ANISOU 1142 CE MET B 505 9537 9092 5582 -1663 -1402 1855 C ATOM 1143 N ASN B 506 39.061 -25.242 28.020 1.00 79.52 N ANISOU 1143 N ASN B 506 9951 11961 8300 -1587 -999 3204 N ATOM 1144 CA ASN B 506 38.795 -26.585 28.487 1.00 86.63 C ANISOU 1144 CA ASN B 506 10502 13030 9384 -1375 -728 3480 C ATOM 1145 C ASN B 506 37.952 -26.434 29.734 1.00 81.73 C ANISOU 1145 C ASN B 506 10075 12552 8426 -1152 -701 3430 C ATOM 1146 O ASN B 506 38.244 -25.574 30.573 1.00 80.43 O ANISOU 1146 O ASN B 506 10205 12509 7846 -1241 -959 3336 O ATOM 1147 CB ASN B 506 40.117 -27.306 28.800 1.00105.06 C ANISOU 1147 CB ASN B 506 12486 15615 11819 -1535 -782 3863 C ATOM 1148 CG ASN B 506 39.913 -28.742 29.245 1.00113.80 C ANISOU 1148 CG ASN B 506 13187 16891 13162 -1319 -478 4180 C ATOM 1149 OD1 ASN B 506 39.244 -29.004 30.242 1.00112.61 O ANISOU 1149 OD1 ASN B 506 13048 16894 12846 -1105 -385 4229 O ATOM 1150 ND2 ASN B 506 40.488 -29.680 28.505 1.00117.89 N ANISOU 1150 ND2 ASN B 506 13341 17374 14079 -1358 -308 4411 N ATOM 1151 N LEU B 507 36.915 -27.256 29.866 1.00 79.45 N ANISOU 1151 N LEU B 507 9628 12244 8314 -854 -397 3501 N ATOM 1152 CA LEU B 507 35.983 -27.126 30.987 1.00 92.27 C ANISOU 1152 CA LEU B 507 11431 13988 9640 -581 -325 3481 C ATOM 1153 C LEU B 507 36.584 -27.574 32.327 1.00110.60 C ANISOU 1153 C LEU B 507 13609 16694 11719 -531 -379 3769 C ATOM 1154 O LEU B 507 36.287 -26.988 33.374 1.00 98.32 O ANISOU 1154 O LEU B 507 12345 15289 9725 -412 -485 3695 O ATOM 1155 CB LEU B 507 34.689 -27.894 30.712 1.00 83.01 C ANISOU 1155 CB LEU B 507 10091 12673 8776 -271 14 3523 C ATOM 1156 CG LEU B 507 33.822 -27.298 29.603 1.00 83.01 C ANISOU 1156 CG LEU B 507 10308 12321 8911 -264 59 3214 C ATOM 1157 CD1 LEU B 507 32.426 -27.902 29.639 1.00 87.87 C ANISOU 1157 CD1 LEU B 507 10816 12831 9740 63 350 3273 C ATOM 1158 CD2 LEU B 507 33.745 -25.771 29.715 1.00 74.65 C ANISOU 1158 CD2 LEU B 507 9765 11174 7426 -372 -180 2889 C ATOM 1159 N GLU B 508 37.403 -28.619 32.301 1.00142.64 N ANISOU 1159 N GLU B 508 17224 20918 16053 -603 -293 4105 N ATOM 1160 CA GLU B 508 38.102 -29.052 33.505 1.00164.24 C ANISOU 1160 CA GLU B 508 19782 24046 18575 -588 -353 4413 C ATOM 1161 C GLU B 508 39.438 -28.325 33.609 1.00167.65 C ANISOU 1161 C GLU B 508 20341 24594 18762 -953 -729 4403 C ATOM 1162 O GLU B 508 40.478 -28.837 33.196 1.00171.02 O ANISOU 1162 O GLU B 508 20456 25087 19436 -1161 -752 4647 O ATOM 1163 CB GLU B 508 38.298 -30.569 33.500 1.00176.25 C ANISOU 1163 CB GLU B 508 20736 25700 20529 -469 -48 4823 C ATOM 1164 CG GLU B 508 39.232 -31.081 32.417 1.00185.16 C ANISOU 1164 CG GLU B 508 21577 26710 22065 -712 -22 4949 C ATOM 1165 CD GLU B 508 38.832 -32.445 31.900 1.00190.46 C ANISOU 1165 CD GLU B 508 21810 27279 23277 -529 352 5164 C ATOM 1166 OE1 GLU B 508 37.686 -32.586 31.421 1.00190.29 O ANISOU 1166 OE1 GLU B 508 21842 27006 23451 -334 527 4987 O ATOM 1167 OE2 GLU B 508 39.667 -33.373 31.959 1.00192.79 O ANISOU 1167 OE2 GLU B 508 21705 27733 23812 -586 467 5517 O ATOM 1168 N ALA B 509 39.397 -27.112 34.147 1.00162.69 N ANISOU 1168 N ALA B 509 20180 23973 17663 -1028 -1026 4128 N ATOM 1169 CA ALA B 509 40.602 -26.325 34.341 1.00166.07 C ANISOU 1169 CA ALA B 509 20760 24495 17843 -1381 -1432 4101 C ATOM 1170 C ALA B 509 41.010 -26.376 35.813 1.00178.38 C ANISOU 1170 C ALA B 509 22346 26457 18973 -1338 -1597 4272 C ATOM 1171 O ALA B 509 41.721 -25.500 36.304 1.00179.11 O ANISOU 1171 O ALA B 509 22708 26637 18707 -1573 -1988 4163 O ATOM 1172 CB ALA B 509 40.370 -24.893 33.891 1.00159.94 C ANISOU 1172 CB ALA B 509 20489 23423 16855 -1530 -1688 3663 C ATOM 1173 N ARG B 510 40.559 -27.421 36.504 1.00187.66 N ANISOU 1173 N ARG B 510 23226 27876 20199 -1032 -1302 4551 N ATOM 1174 CA ARG B 510 40.816 -27.582 37.930 1.00196.15 C ANISOU 1174 CA ARG B 510 24292 29371 20862 -916 -1401 4742 C ATOM 1175 C ARG B 510 42.255 -28.010 38.186 1.00204.33 C ANISOU 1175 C ARG B 510 24993 30701 21944 -1207 -1585 5100 C ATOM 1176 O ARG B 510 43.149 -27.715 37.396 1.00206.91 O ANISOU 1176 O ARG B 510 25269 30884 22463 -1555 -1776 5104 O ATOM 1177 CB ARG B 510 39.860 -28.619 38.523 1.00193.81 C ANISOU 1177 CB ARG B 510 23728 29243 20668 -471 -990 4978 C TER 1178 ARG B 510 ATOM 1179 O5' DT D 1 38.659 -15.913 36.708 1.00122.06 O ANISOU 1179 O5' DT D 1 15990 19145 11240 776 -4375 1647 O ATOM 1180 C5' DT D 1 38.884 -17.211 37.268 1.00119.86 C ANISOU 1180 C5' DT D 1 15540 19073 10929 918 -4117 1751 C ATOM 1181 C4' DT D 1 37.580 -17.834 37.732 1.00114.76 C ANISOU 1181 C4' DT D 1 14964 18571 10070 1318 -3672 1801 C ATOM 1182 O4' DT D 1 36.863 -16.870 38.543 1.00113.28 O ANISOU 1182 O4' DT D 1 15250 18231 9560 1698 -3834 1675 O ATOM 1183 C3' DT D 1 36.609 -18.241 36.616 1.00108.43 C ANISOU 1183 C3' DT D 1 13863 17883 9453 1181 -3252 1923 C ATOM 1184 O3' DT D 1 36.552 -19.675 36.518 1.00113.84 O ANISOU 1184 O3' DT D 1 14232 18793 10228 1175 -2854 2086 O ATOM 1185 C2' DT D 1 35.272 -17.633 37.039 1.00 98.24 C ANISOU 1185 C2' DT D 1 12866 16547 7915 1556 -3134 1874 C ATOM 1186 C1' DT D 1 35.524 -17.279 38.511 1.00106.85 C ANISOU 1186 C1' DT D 1 14396 17544 8657 1961 -3383 1767 C ATOM 1187 N1 DT D 1 34.614 -16.212 38.992 1.00103.08 N ANISOU 1187 N1 DT D 1 14352 16926 7888 2310 -3479 1680 N ATOM 1188 C2 DT D 1 33.599 -16.577 39.852 1.00109.93 C ANISOU 1188 C2 DT D 1 15393 17877 8497 2811 -3162 1755 C ATOM 1189 O2 DT D 1 33.461 -17.720 40.256 1.00119.24 O ANISOU 1189 O2 DT D 1 16391 19229 9686 2962 -2827 1872 O ATOM 1190 N3 DT D 1 32.770 -15.559 40.244 1.00104.95 N ANISOU 1190 N3 DT D 1 15174 17118 7584 3147 -3243 1702 N ATOM 1191 C4 DT D 1 32.872 -14.239 39.835 1.00114.58 C ANISOU 1191 C4 DT D 1 16651 18138 8745 3007 -3618 1563 C ATOM 1192 O4 DT D 1 32.091 -13.373 40.212 1.00119.17 O ANISOU 1192 O4 DT D 1 17626 18618 9034 3342 -3665 1528 O ATOM 1193 C5 DT D 1 33.950 -13.924 38.924 1.00113.71 C ANISOU 1193 C5 DT D 1 16330 17943 8933 2455 -3938 1476 C ATOM 1194 C7 DT D 1 34.108 -12.508 38.433 1.00113.70 C ANISOU 1194 C7 DT D 1 16594 17716 8892 2271 -4339 1326 C ATOM 1195 C6 DT D 1 34.770 -14.917 38.550 1.00105.57 C ANISOU 1195 C6 DT D 1 14882 17037 8194 2140 -3850 1549 C ATOM 1196 P DG D 2 36.033 -20.391 35.170 1.00116.76 P ANISOU 1196 P DG D 2 14208 19272 10884 897 -2490 2249 P ATOM 1197 OP1 DG D 2 36.896 -21.577 34.946 1.00124.74 O ANISOU 1197 OP1 DG D 2 14934 20432 12028 710 -2356 2385 O ATOM 1198 OP2 DG D 2 35.906 -19.365 34.128 1.00 95.08 O ANISOU 1198 OP2 DG D 2 11461 16359 8305 640 -2663 2186 O ATOM 1199 O5' DG D 2 34.586 -20.905 35.614 1.00102.31 O ANISOU 1199 O5' DG D 2 12409 17560 8905 1257 -2087 2326 O ATOM 1200 C5' DG D 2 34.472 -21.674 36.816 1.00100.74 C ANISOU 1200 C5' DG D 2 12309 17486 8482 1617 -1909 2363 C ATOM 1201 C4' DG D 2 33.003 -21.881 37.104 1.00100.76 C ANISOU 1201 C4' DG D 2 12339 17559 8387 1943 -1551 2454 C ATOM 1202 O4' DG D 2 32.457 -20.639 37.613 1.00 92.09 O ANISOU 1202 O4' DG D 2 11604 16312 7075 2217 -1742 2334 O ATOM 1203 C3' DG D 2 32.188 -22.254 35.863 1.00 97.80 C ANISOU 1203 C3' DG D 2 11639 17236 8284 1696 -1287 2591 C ATOM 1204 O3' DG D 2 31.273 -23.334 36.163 1.00105.23 O ANISOU 1204 O3' DG D 2 12419 18340 9222 1901 -857 2771 O ATOM 1205 C2' DG D 2 31.514 -20.928 35.499 1.00 96.56 C ANISOU 1205 C2' DG D 2 11662 16925 8103 1726 -1454 2487 C ATOM 1206 C1' DG D 2 31.333 -20.256 36.854 1.00 99.50 C ANISOU 1206 C1' DG D 2 12448 17239 8119 2184 -1578 2390 C ATOM 1207 N9 DG D 2 31.343 -18.793 36.842 1.00104.33 N ANISOU 1207 N9 DG D 2 13388 17658 8596 2217 -1931 2221 N ATOM 1208 C8 DG D 2 32.240 -17.966 36.212 1.00104.66 C ANISOU 1208 C8 DG D 2 13482 17544 8741 1876 -2319 2078 C ATOM 1209 N7 DG D 2 31.997 -16.700 36.413 1.00107.82 N ANISOU 1209 N7 DG D 2 14236 17780 8950 2010 -2581 1942 N ATOM 1210 C5 DG D 2 30.873 -16.674 37.232 1.00102.82 C ANISOU 1210 C5 DG D 2 13808 17203 8056 2491 -2348 2007 C ATOM 1211 C6 DG D 2 30.142 -15.589 37.788 1.00102.59 C ANISOU 1211 C6 DG D 2 14207 17062 7710 2860 -2453 1940 C ATOM 1212 O6 DG D 2 30.311 -14.368 37.684 1.00106.02 O ANISOU 1212 O6 DG D 2 14962 17316 8005 2831 -2800 1786 O ATOM 1213 N1 DG D 2 29.077 -16.026 38.554 1.00104.19 N ANISOU 1213 N1 DG D 2 14472 17382 7732 3328 -2091 2093 N ATOM 1214 C2 DG D 2 28.761 -17.338 38.772 1.00106.14 C ANISOU 1214 C2 DG D 2 14403 17821 8103 3412 -1687 2276 C ATOM 1215 N2 DG D 2 27.697 -17.560 39.553 1.00116.48 N ANISOU 1215 N2 DG D 2 15819 19213 9226 3899 -1360 2431 N ATOM 1216 N3 DG D 2 29.426 -18.362 38.265 1.00102.21 N ANISOU 1216 N3 DG D 2 13526 17425 7884 3059 -1600 2323 N ATOM 1217 C4 DG D 2 30.467 -17.958 37.504 1.00103.33 C ANISOU 1217 C4 DG D 2 13606 17463 8192 2618 -1941 2185 C ATOM 1218 P DG D 3 30.437 -24.136 35.039 1.00106.64 P ANISOU 1218 P DG D 3 12233 18594 9690 1670 -547 2961 P ATOM 1219 OP1 DG D 3 30.194 -25.518 35.507 1.00110.04 O ANISOU 1219 OP1 DG D 3 12503 19201 10108 1796 -195 3135 O ATOM 1220 OP2 DG D 3 31.057 -23.900 33.719 1.00103.41 O ANISOU 1220 OP2 DG D 3 11680 18087 9524 1225 -739 2927 O ATOM 1221 O5' DG D 3 29.041 -23.383 35.092 1.00 99.56 O ANISOU 1221 O5' DG D 3 11417 17653 8760 1911 -444 2982 O ATOM 1222 C5' DG D 3 28.236 -23.579 36.237 1.00109.25 C ANISOU 1222 C5' DG D 3 12763 18965 9784 2371 -201 3070 C ATOM 1223 C4' DG D 3 27.181 -22.495 36.285 1.00118.17 C ANISOU 1223 C4' DG D 3 14052 20019 10830 2601 -215 3052 C ATOM 1224 O4' DG D 3 27.826 -21.207 36.188 1.00114.67 O ANISOU 1224 O4' DG D 3 13904 19408 10256 2531 -623 2824 O ATOM 1225 C3' DG D 3 26.179 -22.502 35.135 1.00123.46 C ANISOU 1225 C3' DG D 3 14441 20689 11781 2391 -76 3163 C ATOM 1226 O3' DG D 3 24.921 -22.904 35.658 1.00134.22 O ANISOU 1226 O3' DG D 3 15704 22161 13133 2722 280 3374 O ATOM 1227 C2' DG D 3 26.167 -21.048 34.658 1.00117.18 C ANISOU 1227 C2' DG D 3 13871 19733 10920 2330 -384 2974 C ATOM 1228 C1' DG D 3 26.800 -20.331 35.846 1.00114.12 C ANISOU 1228 C1' DG D 3 13906 19283 10173 2638 -607 2826 C ATOM 1229 N9 DG D 3 27.364 -19.038 35.495 1.00104.96 N ANISOU 1229 N9 DG D 3 13012 17944 8924 2498 -1009 2602 N ATOM 1230 C8 DG D 3 28.456 -18.804 34.702 1.00 96.33 C ANISOU 1230 C8 DG D 3 11866 16748 7987 2076 -1300 2466 C ATOM 1231 N7 DG D 3 28.709 -17.533 34.553 1.00 96.51 N ANISOU 1231 N7 DG D 3 12170 16606 7892 2039 -1627 2285 N ATOM 1232 C5 DG D 3 27.724 -16.885 35.293 1.00 99.10 C ANISOU 1232 C5 DG D 3 12781 16931 7939 2475 -1554 2296 C ATOM 1233 C6 DG D 3 27.486 -15.499 35.503 1.00101.29 C ANISOU 1233 C6 DG D 3 13470 17064 7954 2656 -1806 2150 C ATOM 1234 O6 DG D 3 28.116 -14.518 35.068 1.00 93.76 O ANISOU 1234 O6 DG D 3 12709 15941 6974 2439 -2167 1963 O ATOM 1235 N1 DG D 3 26.377 -15.285 36.313 1.00106.80 N ANISOU 1235 N1 DG D 3 14371 17822 8386 3155 -1593 2257 N ATOM 1236 C2 DG D 3 25.606 -16.280 36.858 1.00111.09 C ANISOU 1236 C2 DG D 3 14718 18540 8953 3435 -1182 2485 C ATOM 1237 N2 DG D 3 24.584 -15.865 37.623 1.00118.86 N ANISOU 1237 N2 DG D 3 15945 19552 9662 3940 -1007 2594 N ATOM 1238 N3 DG D 3 25.817 -17.579 36.668 1.00101.99 N ANISOU 1238 N3 DG D 3 13172 17517 8062 3247 -951 2614 N ATOM 1239 C4 DG D 3 26.886 -17.803 35.873 1.00 99.19 C ANISOU 1239 C4 DG D 3 12643 17110 7935 2770 -1162 2503 C ATOM 1240 P DA D 4 23.680 -23.248 34.710 1.00138.72 P ANISOU 1240 P DA D 4 15920 22768 14019 2578 505 3567 P ATOM 1241 OP1 DA D 4 23.186 -24.585 35.117 1.00142.02 O ANISOU 1241 OP1 DA D 4 16076 23333 14551 2677 871 3821 O ATOM 1242 OP2 DA D 4 24.044 -22.960 33.309 1.00128.52 O ANISOU 1242 OP2 DA D 4 14515 21357 12961 2118 273 3452 O ATOM 1243 O5' DA D 4 22.612 -22.164 35.179 1.00138.58 O ANISOU 1243 O5' DA D 4 16098 22733 13823 2973 553 3590 O ATOM 1244 C5' DA D 4 22.366 -22.083 36.567 1.00142.35 C ANISOU 1244 C5' DA D 4 16818 23271 13999 3488 711 3663 C ATOM 1245 C4' DA D 4 21.521 -20.866 36.836 1.00142.39 C ANISOU 1245 C4' DA D 4 17076 23229 13798 3829 684 3657 C ATOM 1246 O4' DA D 4 22.304 -19.686 36.553 1.00131.49 O ANISOU 1246 O4' DA D 4 16031 21689 12240 3697 264 3366 O ATOM 1247 C3' DA D 4 20.286 -20.809 35.957 1.00145.88 C ANISOU 1247 C3' DA D 4 17205 23714 14510 3730 852 3819 C ATOM 1248 O3' DA D 4 19.183 -20.516 36.786 1.00153.13 O ANISOU 1248 O3' DA D 4 18210 24710 15264 4245 1121 4028 O ATOM 1249 C2' DA D 4 20.591 -19.703 34.944 1.00139.96 C ANISOU 1249 C2' DA D 4 16590 22818 13769 3435 497 3568 C ATOM 1250 C1' DA D 4 21.641 -18.845 35.643 1.00129.70 C ANISOU 1250 C1' DA D 4 15773 21406 12102 3570 180 3321 C ATOM 1251 N9 DA D 4 22.695 -18.297 34.791 1.00114.23 N ANISOU 1251 N9 DA D 4 13901 19298 10203 3143 -204 3053 N ATOM 1252 C8 DA D 4 23.576 -19.003 34.025 1.00105.52 C ANISOU 1252 C8 DA D 4 12556 18171 9364 2691 -298 2999 C ATOM 1253 N7 DA D 4 24.433 -18.249 33.375 1.00 97.90 N ANISOU 1253 N7 DA D 4 11735 17057 8407 2399 -640 2773 N ATOM 1254 C5 DA D 4 24.100 -16.957 33.742 1.00 96.03 C ANISOU 1254 C5 DA D 4 11871 16735 7881 2658 -802 2652 C ATOM 1255 C6 DA D 4 24.632 -15.693 33.391 1.00 95.30 C ANISOU 1255 C6 DA D 4 12091 16468 7652 2538 -1167 2409 C ATOM 1256 N6 DA D 4 25.666 -15.503 32.555 1.00 89.36 N ANISOU 1256 N6 DA D 4 11292 15589 7071 2111 -1433 2250 N ATOM 1257 N1 DA D 4 24.049 -14.606 33.944 1.00 96.59 N ANISOU 1257 N1 DA D 4 12633 16584 7481 2895 -1242 2352 N ATOM 1258 C2 DA D 4 23.020 -14.775 34.781 1.00 92.09 C ANISOU 1258 C2 DA D 4 12117 16138 6737 3358 -955 2543 C ATOM 1259 N3 DA D 4 22.437 -15.903 35.177 1.00 97.01 N ANISOU 1259 N3 DA D 4 12441 16927 7492 3514 -586 2792 N ATOM 1260 C4 DA D 4 23.030 -16.971 34.617 1.00102.32 C ANISOU 1260 C4 DA D 4 12746 17639 8490 3131 -536 2824 C ATOM 1261 P DA D 5 17.711 -20.625 36.193 1.00173.69 P ANISOU 1261 P DA D 5 20446 27402 18146 4266 1386 4291 P ATOM 1262 OP1 DA D 5 16.797 -20.986 37.297 1.00180.36 O ANISOU 1262 OP1 DA D 5 21259 28374 18895 4795 1786 4609 O ATOM 1263 OP2 DA D 5 17.769 -21.443 34.964 1.00170.54 O ANISOU 1263 OP2 DA D 5 19619 26994 18183 3722 1352 4308 O ATOM 1264 O5' DA D 5 17.446 -19.116 35.754 1.00151.88 O ANISOU 1264 O5' DA D 5 17977 24542 15189 4324 1137 4108 O ATOM 1265 C5' DA D 5 17.902 -18.082 36.603 1.00150.40 C ANISOU 1265 C5' DA D 5 18333 24272 14539 4674 952 3942 C ATOM 1266 C4' DA D 5 17.727 -16.757 35.906 1.00144.50 C ANISOU 1266 C4' DA D 5 17816 23422 13665 4598 687 3744 C ATOM 1267 O4' DA D 5 18.912 -16.435 35.144 1.00133.13 O ANISOU 1267 O4' DA D 5 16474 21832 12276 4132 296 3423 O ATOM 1268 C3' DA D 5 16.574 -16.783 34.920 1.00150.25 C ANISOU 1268 C3' DA D 5 18166 24218 14704 4455 846 3890 C ATOM 1269 O3' DA D 5 15.647 -15.786 35.322 1.00158.98 O ANISOU 1269 O3' DA D 5 19526 25359 15522 4903 932 3976 O ATOM 1270 C2' DA D 5 17.217 -16.530 33.550 1.00140.88 C ANISOU 1270 C2' DA D 5 16894 22894 13740 3885 526 3614 C ATOM 1271 C1' DA D 5 18.551 -15.884 33.898 1.00129.97 C ANISOU 1271 C1' DA D 5 15951 21371 12060 3827 174 3315 C ATOM 1272 N9 DA D 5 19.653 -16.165 32.975 1.00116.22 N ANISOU 1272 N9 DA D 5 14092 19514 10554 3290 -81 3108 N ATOM 1273 C8 DA D 5 20.035 -17.388 32.495 1.00115.64 C ANISOU 1273 C8 DA D 5 13639 19474 10826 2953 7 3192 C ATOM 1274 N7 DA D 5 21.071 -17.344 31.680 1.00105.56 N ANISOU 1274 N7 DA D 5 12361 18067 9679 2533 -256 2991 N ATOM 1275 C5 DA D 5 21.403 -16.006 31.629 1.00 94.74 C ANISOU 1275 C5 DA D 5 11375 16567 8054 2576 -541 2752 C ATOM 1276 C6 DA D 5 22.417 -15.308 30.948 1.00 90.27 C ANISOU 1276 C6 DA D 5 10983 15825 7491 2256 -884 2492 C ATOM 1277 N6 DA D 5 23.314 -15.903 30.147 1.00 86.35 N ANISOU 1277 N6 DA D 5 10281 15258 7271 1836 -982 2442 N ATOM 1278 N1 DA D 5 22.467 -13.961 31.095 1.00 90.78 N ANISOU 1278 N1 DA D 5 11453 15780 7260 2392 -1118 2301 N ATOM 1279 C2 DA D 5 21.563 -13.369 31.886 1.00 92.55 C ANISOU 1279 C2 DA D 5 11918 16073 7176 2844 -1011 2371 C ATOM 1280 N3 DA D 5 20.573 -13.929 32.586 1.00100.41 N ANISOU 1280 N3 DA D 5 12781 17237 8133 3204 -676 2629 N ATOM 1281 C4 DA D 5 20.541 -15.263 32.417 1.00103.07 C ANISOU 1281 C4 DA D 5 12687 17677 8799 3035 -450 2811 C ATOM 1282 P DC D 6 14.538 -15.258 34.304 1.00180.20 P ANISOU 1282 P DC D 6 22001 28079 18389 4813 979 4029 P ATOM 1283 OP1 DC D 6 13.644 -14.338 35.038 1.00182.36 O ANISOU 1283 OP1 DC D 6 22584 28420 18284 5389 1124 4172 O ATOM 1284 OP2 DC D 6 13.980 -16.417 33.573 1.00182.83 O ANISOU 1284 OP2 DC D 6 21728 28492 19249 4500 1179 4239 O ATOM 1285 O5' DC D 6 15.433 -14.415 33.290 1.00152.13 O ANISOU 1285 O5' DC D 6 18672 24335 14797 4386 544 3620 O ATOM 1286 C5' DC D 6 14.852 -13.373 32.550 1.00149.22 C ANISOU 1286 C5' DC D 6 18425 23922 14352 4378 435 3501 C ATOM 1287 C4' DC D 6 15.824 -12.217 32.491 1.00138.70 C ANISOU 1287 C4' DC D 6 17617 22412 12672 4306 47 3140 C ATOM 1288 O4' DC D 6 17.176 -12.712 32.315 1.00132.91 O ANISOU 1288 O4' DC D 6 16861 21563 12075 3914 -180 2957 O ATOM 1289 C3' DC D 6 15.516 -11.269 31.348 1.00129.55 C ANISOU 1289 C3' DC D 6 16534 21159 11531 4107 -126 2929 C ATOM 1290 O3' DC D 6 15.257 -9.987 31.870 1.00129.95 O ANISOU 1290 O3' DC D 6 17106 21185 11084 4492 -224 2841 O ATOM 1291 C2' DC D 6 16.749 -11.251 30.451 1.00124.75 C ANISOU 1291 C2' DC D 6 15935 20359 11104 3573 -451 2623 C ATOM 1292 C1' DC D 6 17.774 -12.118 31.172 1.00126.20 C ANISOU 1292 C1' DC D 6 16075 20546 11331 3494 -479 2664 C ATOM 1293 N1 DC D 6 18.372 -13.175 30.294 1.00116.76 N ANISOU 1293 N1 DC D 6 14466 19307 10592 3001 -494 2654 N ATOM 1294 C2 DC D 6 19.417 -12.813 29.434 1.00106.81 C ANISOU 1294 C2 DC D 6 13299 17860 9423 2594 -798 2384 C ATOM 1295 O2 DC D 6 19.795 -11.628 29.433 1.00 99.03 O ANISOU 1295 O2 DC D 6 12715 16754 8158 2632 -1050 2157 O ATOM 1296 N3 DC D 6 19.974 -13.772 28.639 1.00104.99 N ANISOU 1296 N3 DC D 6 12733 17582 9577 2188 -801 2401 N ATOM 1297 C4 DC D 6 19.518 -15.032 28.695 1.00107.64 C ANISOU 1297 C4 DC D 6 12676 18043 10180 2166 -540 2654 C ATOM 1298 N4 DC D 6 20.094 -15.942 27.905 1.00102.47 N ANISOU 1298 N4 DC D 6 11752 17324 9858 1784 -563 2670 N ATOM 1299 C5 DC D 6 18.456 -15.417 29.569 1.00113.50 C ANISOU 1299 C5 DC D 6 13299 18973 10855 2548 -239 2922 C ATOM 1300 C6 DC D 6 17.919 -14.465 30.344 1.00119.27 C ANISOU 1300 C6 DC D 6 14346 19754 11218 2965 -215 2920 C ATOM 1301 P DC D 7 14.264 -9.041 31.050 1.00131.47 P ANISOU 1301 P DC D 7 17358 21388 11206 4557 -210 2779 P ATOM 1302 OP1 DC D 7 14.039 -7.830 31.863 1.00132.48 O ANISOU 1302 OP1 DC D 7 18084 21511 10743 5040 -280 2740 O ATOM 1303 OP2 DC D 7 13.126 -9.881 30.620 1.00138.60 O ANISOU 1303 OP2 DC D 7 17703 22450 12510 4548 115 3069 O ATOM 1304 O5' DC D 7 15.092 -8.622 29.750 1.00117.18 O ANISOU 1304 O5' DC D 7 15580 19368 9575 4014 -542 2408 O ATOM 1305 C5' DC D 7 16.380 -8.032 29.893 1.00113.72 C ANISOU 1305 C5' DC D 7 15538 18746 8922 3848 -890 2126 C ATOM 1306 C4' DC D 7 17.031 -7.907 28.529 1.00108.40 C ANISOU 1306 C4' DC D 7 14747 17891 8548 3318 -1108 1857 C ATOM 1307 O4' DC D 7 17.668 -9.164 28.168 1.00107.04 O ANISOU 1307 O4' DC D 7 14143 17706 8823 2949 -1068 1931 O ATOM 1308 C3' DC D 7 16.038 -7.589 27.414 1.00105.22 C ANISOU 1308 C3' DC D 7 14181 17490 8306 3253 -1012 1818 C ATOM 1309 O3' DC D 7 16.648 -6.740 26.444 1.00103.67 O ANISOU 1309 O3' DC D 7 14217 17080 8092 2960 -1285 1483 O ATOM 1310 C2' DC D 7 15.768 -8.969 26.822 1.00106.89 C ANISOU 1310 C2' DC D 7 13794 17758 9059 2991 -818 2011 C ATOM 1311 C1' DC D 7 17.178 -9.546 26.888 1.00107.83 C ANISOU 1311 C1' DC D 7 13886 17765 9318 2665 -991 1923 C ATOM 1312 N1 DC D 7 17.268 -11.038 26.699 1.00106.53 N ANISOU 1312 N1 DC D 7 13227 17661 9590 2442 -826 2134 N ATOM 1313 C2 DC D 7 18.362 -11.548 25.997 1.00 98.73 C ANISOU 1313 C2 DC D 7 12123 16522 8867 2017 -983 2018 C ATOM 1314 O2 DC D 7 19.208 -10.744 25.572 1.00 93.94 O ANISOU 1314 O2 DC D 7 11795 15741 8156 1840 -1241 1757 O ATOM 1315 N3 DC D 7 18.460 -12.890 25.807 1.00 95.12 N ANISOU 1315 N3 DC D 7 11266 16110 8764 1825 -844 2209 N ATOM 1316 C4 DC D 7 17.529 -13.709 26.293 1.00105.35 C ANISOU 1316 C4 DC D 7 12269 17585 10173 2017 -571 2498 C ATOM 1317 N4 DC D 7 17.687 -15.021 26.078 1.00105.99 N ANISOU 1317 N4 DC D 7 11991 17692 10588 1805 -460 2674 N ATOM 1318 C5 DC D 7 16.400 -13.209 27.014 1.00108.09 C ANISOU 1318 C5 DC D 7 12690 18089 10291 2444 -394 2637 C ATOM 1319 C6 DC D 7 16.311 -11.882 27.190 1.00110.18 C ANISOU 1319 C6 DC D 7 13367 18314 10183 2654 -525 2451 C ATOM 1320 P DC D 8 15.799 -5.615 25.695 1.00121.89 P ANISOU 1320 P DC D 8 16749 19347 10215 3074 -1303 1315 P ATOM 1321 OP1 DC D 8 16.092 -4.342 26.384 1.00114.55 O ANISOU 1321 OP1 DC D 8 16431 18365 8728 3332 -1502 1152 O ATOM 1322 OP2 DC D 8 14.406 -6.104 25.536 1.00119.48 O ANISOU 1322 OP2 DC D 8 16086 19227 10083 3274 -998 1565 O ATOM 1323 O5' DC D 8 16.437 -5.558 24.219 1.00112.57 O ANISOU 1323 O5' DC D 8 15470 17927 9374 2585 -1479 1045 O ATOM 1324 C5' DC D 8 17.864 -5.648 24.119 1.00112.11 C ANISOU 1324 C5' DC D 8 15492 17695 9410 2255 -1714 898 C ATOM 1325 C4' DC D 8 18.321 -6.509 22.944 1.00 99.16 C ANISOU 1325 C4' DC D 8 13473 15916 8287 1827 -1710 875 C ATOM 1326 O4' DC D 8 18.201 -7.920 23.266 1.00100.89 O ANISOU 1326 O4' DC D 8 13248 16272 8812 1784 -1518 1162 O ATOM 1327 C3' DC D 8 17.550 -6.301 21.664 1.00 95.42 C ANISOU 1327 C3' DC D 8 12901 15344 8010 1743 -1652 765 C ATOM 1328 O3' DC D 8 18.455 -6.091 20.607 1.00 88.88 O ANISOU 1328 O3' DC D 8 12142 14254 7376 1398 -1825 542 O ATOM 1329 C2' DC D 8 16.785 -7.606 21.484 1.00 96.53 C ANISOU 1329 C2' DC D 8 12535 15607 8535 1723 -1419 1046 C ATOM 1330 C1' DC D 8 17.772 -8.571 22.105 1.00 96.37 C ANISOU 1330 C1' DC D 8 12345 15622 8650 1568 -1429 1194 C ATOM 1331 N1 DC D 8 17.169 -9.846 22.515 1.00 98.18 N ANISOU 1331 N1 DC D 8 12151 16030 9121 1630 -1197 1517 N ATOM 1332 C2 DC D 8 17.848 -11.031 22.222 1.00 93.97 C ANISOU 1332 C2 DC D 8 11327 15446 8932 1341 -1184 1629 C ATOM 1333 O2 DC D 8 18.932 -10.970 21.640 1.00 95.31 O ANISOU 1333 O2 DC D 8 11590 15430 9194 1062 -1355 1472 O ATOM 1334 N3 DC D 8 17.314 -12.217 22.582 1.00 93.78 N ANISOU 1334 N3 DC D 8 10931 15574 9127 1382 -979 1924 N ATOM 1335 C4 DC D 8 16.149 -12.233 23.212 1.00101.57 C ANISOU 1335 C4 DC D 8 11807 16757 10029 1696 -781 2117 C ATOM 1336 N4 DC D 8 15.669 -13.432 23.544 1.00106.82 N ANISOU 1336 N4 DC D 8 12090 17555 10940 1711 -579 2419 N ATOM 1337 C5 DC D 8 15.437 -11.033 23.523 1.00103.71 C ANISOU 1337 C5 DC D 8 12358 17092 9955 2013 -775 2028 C ATOM 1338 C6 DC D 8 15.972 -9.863 23.157 1.00 99.31 C ANISOU 1338 C6 DC D 8 12200 16383 9150 1971 -991 1718 C ATOM 1339 P DA D 9 17.970 -5.078 19.456 1.00109.55 P ANISOU 1339 P DA D 9 14991 16693 9939 1388 -1883 266 P ATOM 1340 OP1 DA D 9 18.161 -3.695 19.958 1.00107.24 O ANISOU 1340 OP1 DA D 9 15207 16381 9160 1560 -2041 59 O ATOM 1341 OP2 DA D 9 16.654 -5.506 18.911 1.00 98.16 O ANISOU 1341 OP2 DA D 9 13279 15328 8688 1506 -1693 374 O ATOM 1342 O5' DA D 9 19.068 -5.379 18.341 1.00 97.14 O ANISOU 1342 O5' DA D 9 13350 14837 8722 989 -2004 137 O ATOM 1343 C5' DA D 9 20.232 -6.128 18.718 1.00 89.45 C ANISOU 1343 C5' DA D 9 12223 13848 7914 771 -2066 261 C ATOM 1344 C4' DA D 9 20.422 -7.250 17.714 1.00 90.68 C ANISOU 1344 C4' DA D 9 12037 13874 8542 522 -1986 367 C ATOM 1345 O4' DA D 9 19.857 -8.476 18.242 1.00100.67 O ANISOU 1345 O4' DA D 9 12933 15346 9972 591 -1811 662 O ATOM 1346 C3' DA D 9 19.751 -7.005 16.360 1.00 91.77 C ANISOU 1346 C3' DA D 9 12201 13811 8855 494 -1957 217 C ATOM 1347 O3' DA D 9 20.780 -6.814 15.403 1.00 94.39 O ANISOU 1347 O3' DA D 9 12652 13854 9360 245 -2068 70 O ATOM 1348 C2' DA D 9 18.881 -8.235 16.058 1.00 87.85 C ANISOU 1348 C2' DA D 9 11313 13385 8682 502 -1797 452 C ATOM 1349 C1' DA D 9 19.140 -9.177 17.231 1.00 92.03 C ANISOU 1349 C1' DA D 9 11594 14158 9214 520 -1713 732 C ATOM 1350 N9 DA D 9 17.962 -9.714 17.892 1.00 90.10 N ANISOU 1350 N9 DA D 9 11104 14161 8968 738 -1540 959 N ATOM 1351 C8 DA D 9 16.907 -9.020 18.417 1.00 92.85 C ANISOU 1351 C8 DA D 9 11545 14678 9054 1042 -1463 954 C ATOM 1352 N7 DA D 9 16.010 -9.801 18.987 1.00 99.96 N ANISOU 1352 N7 DA D 9 12133 15791 10054 1192 -1281 1235 N ATOM 1353 C5 DA D 9 16.512 -11.083 18.827 1.00 95.13 C ANISOU 1353 C5 DA D 9 11225 15143 9777 960 -1251 1415 C ATOM 1354 C6 DA D 9 16.039 -12.356 19.191 1.00 90.25 C ANISOU 1354 C6 DA D 9 10216 14667 9409 956 -1092 1731 C ATOM 1355 N6 DA D 9 14.907 -12.588 19.848 1.00 80.68 N ANISOU 1355 N6 DA D 9 8795 13677 8184 1200 -911 1958 N ATOM 1356 N1 DA D 9 16.795 -13.417 18.870 1.00 94.76 N ANISOU 1356 N1 DA D 9 10618 15144 10245 696 -1115 1830 N ATOM 1357 C2 DA D 9 17.945 -13.216 18.225 1.00 88.99 C ANISOU 1357 C2 DA D 9 10076 14197 9538 471 -1272 1646 C ATOM 1358 N3 DA D 9 18.495 -12.073 17.833 1.00 84.59 N ANISOU 1358 N3 DA D 9 9855 13488 8798 446 -1419 1363 N ATOM 1359 C4 DA D 9 17.723 -11.038 18.164 1.00 91.15 C ANISOU 1359 C4 DA D 9 10863 14410 9358 691 -1408 1249 C ATOM 1360 P DA D 10 20.728 -7.554 13.988 1.00102.71 P ANISOU 1360 P DA D 10 13550 14650 10826 88 -2018 89 P ATOM 1361 OP1 DA D 10 21.759 -6.894 13.139 1.00 95.08 O ANISOU 1361 OP1 DA D 10 12834 13384 9909 -78 -2128 -110 O ATOM 1362 OP2 DA D 10 19.329 -7.592 13.501 1.00 88.35 O ANISOU 1362 OP2 DA D 10 11665 12844 9061 255 -1934 67 O ATOM 1363 O5' DA D 10 21.204 -9.049 14.376 1.00 93.82 O ANISOU 1363 O5' DA D 10 12061 13630 9956 -50 -1945 409 O ATOM 1364 C5' DA D 10 21.434 -9.898 13.264 1.00 83.91 C ANISOU 1364 C5' DA D 10 10685 12142 9055 -206 -1921 488 C ATOM 1365 C4' DA D 10 20.608 -11.158 13.201 1.00 74.62 C ANISOU 1365 C4' DA D 10 9190 11048 8114 -187 -1816 733 C ATOM 1366 O4' DA D 10 19.515 -11.154 14.140 1.00 72.63 O ANISOU 1366 O4' DA D 10 8794 11089 7714 10 -1731 825 O ATOM 1367 C3' DA D 10 19.983 -11.381 11.832 1.00 81.07 C ANISOU 1367 C3' DA D 10 10036 11577 9188 -197 -1835 673 C ATOM 1368 O3' DA D 10 20.623 -12.514 11.243 1.00 77.84 O ANISOU 1368 O3' DA D 10 9514 11002 9058 -362 -1832 858 O ATOM 1369 C2' DA D 10 18.480 -11.598 12.102 1.00 68.75 C ANISOU 1369 C2' DA D 10 8282 10188 7650 -31 -1772 757 C ATOM 1370 C1' DA D 10 18.535 -12.014 13.577 1.00 71.02 C ANISOU 1370 C1' DA D 10 8358 10842 7786 21 -1674 972 C ATOM 1371 N9 DA D 10 17.282 -11.910 14.340 1.00 76.47 N ANISOU 1371 N9 DA D 10 8890 11798 8366 240 -1574 1070 N ATOM 1372 C8 DA D 10 16.642 -10.755 14.684 1.00 80.57 C ANISOU 1372 C8 DA D 10 9592 12427 8594 458 -1565 907 C ATOM 1373 N7 DA D 10 15.537 -10.951 15.381 1.00 84.99 N ANISOU 1373 N7 DA D 10 9940 13236 9115 656 -1440 1090 N ATOM 1374 C5 DA D 10 15.429 -12.323 15.512 1.00 82.25 C ANISOU 1374 C5 DA D 10 9239 12944 9070 544 -1367 1383 C ATOM 1375 C6 DA D 10 14.482 -13.162 16.142 1.00 79.23 C ANISOU 1375 C6 DA D 10 8495 12783 8827 645 -1219 1694 C ATOM 1376 N6 DA D 10 13.409 -12.725 16.794 1.00 85.42 N ANISOU 1376 N6 DA D 10 9196 13794 9465 914 -1097 1785 N ATOM 1377 N1 DA D 10 14.672 -14.495 16.087 1.00 85.30 N ANISOU 1377 N1 DA D 10 8988 13531 9891 470 -1188 1933 N ATOM 1378 C2 DA D 10 15.752 -14.956 15.448 1.00 84.85 C ANISOU 1378 C2 DA D 10 9027 13255 9956 231 -1294 1873 C ATOM 1379 N3 DA D 10 16.704 -14.260 14.829 1.00 78.34 N ANISOU 1379 N3 DA D 10 8517 12219 9030 135 -1419 1613 N ATOM 1380 C4 DA D 10 16.504 -12.933 14.887 1.00 81.19 C ANISOU 1380 C4 DA D 10 9135 12593 9121 288 -1454 1368 C ATOM 1381 P DT D 11 20.469 -12.740 9.690 1.00 83.76 P ANISOU 1381 P DT D 11 10408 11348 10070 -391 -1892 788 P ATOM 1382 OP1 DT D 11 21.750 -13.378 9.228 1.00 80.02 O ANISOU 1382 OP1 DT D 11 9979 10690 9736 -545 -1892 917 O ATOM 1383 OP2 DT D 11 20.110 -11.407 9.158 1.00 78.13 O ANISOU 1383 OP2 DT D 11 9982 10489 9214 -275 -1943 464 O ATOM 1384 O5' DT D 11 19.254 -13.785 9.610 1.00 62.17 O ANISOU 1384 O5' DT D 11 7408 8664 7549 -352 -1879 991 O ATOM 1385 C5' DT D 11 19.530 -15.073 10.329 1.00 64.49 C ANISOU 1385 C5' DT D 11 7414 9154 7937 -454 -1810 1315 C ATOM 1386 C4' DT D 11 18.419 -16.164 10.370 1.00 67.66 C ANISOU 1386 C4' DT D 11 7528 9619 8560 -447 -1800 1554 C ATOM 1387 O4' DT D 11 17.466 -15.679 11.350 1.00 78.86 O ANISOU 1387 O4' DT D 11 8775 11357 9829 -301 -1720 1554 O ATOM 1388 C3' DT D 11 17.617 -16.619 9.119 1.00 64.11 C ANISOU 1388 C3' DT D 11 7123 8837 8400 -447 -1927 1562 C ATOM 1389 O3' DT D 11 17.968 -18.002 8.856 1.00 55.42 O ANISOU 1389 O3' DT D 11 5926 7626 7503 -580 -1953 1832 O ATOM 1390 C2' DT D 11 16.145 -16.568 9.549 1.00 63.51 C ANISOU 1390 C2' DT D 11 6794 8956 8381 -337 -1912 1622 C ATOM 1391 C1' DT D 11 16.161 -16.165 11.041 1.00 70.47 C ANISOU 1391 C1' DT D 11 7510 10273 8991 -252 -1748 1674 C ATOM 1392 N1 DT D 11 15.102 -15.189 11.667 1.00 72.30 N ANISOU 1392 N1 DT D 11 7682 10747 9041 -39 -1680 1580 N ATOM 1393 C2 DT D 11 14.027 -15.732 12.346 1.00 82.23 C ANISOU 1393 C2 DT D 11 8594 12247 10403 42 -1587 1831 C ATOM 1394 O2 DT D 11 13.817 -16.944 12.413 1.00 75.97 O ANISOU 1394 O2 DT D 11 7538 11465 9862 -68 -1575 2106 O ATOM 1395 N3 DT D 11 13.165 -14.800 12.895 1.00 99.35 N ANISOU 1395 N3 DT D 11 10745 14631 12374 267 -1507 1763 N ATOM 1396 C4 DT D 11 13.275 -13.410 12.855 1.00102.96 C ANISOU 1396 C4 DT D 11 11518 15086 12515 411 -1523 1460 C ATOM 1397 O4 DT D 11 12.451 -12.641 13.363 1.00106.56 O ANISOU 1397 O4 DT D 11 11970 15744 12773 636 -1444 1431 O ATOM 1398 C5 DT D 11 14.438 -12.908 12.163 1.00 88.67 C ANISOU 1398 C5 DT D 11 10060 13016 10615 291 -1633 1195 C ATOM 1399 C7 DT D 11 14.639 -11.417 12.064 1.00 76.49 C ANISOU 1399 C7 DT D 11 8885 11438 8739 418 -1666 861 C ATOM 1400 C6 DT D 11 15.282 -13.811 11.629 1.00 76.74 C ANISOU 1400 C6 DT D 11 8537 11299 9320 80 -1695 1279 C ATOM 1401 P DG D 12 17.560 -18.746 7.523 1.00 58.29 P ANISOU 1401 P DG D 12 6415 7571 8160 -611 -2123 1896 P ATOM 1402 OP1 DG D 12 18.366 -19.967 7.600 1.00 58.31 O ANISOU 1402 OP1 DG D 12 6379 7552 8223 -738 -2099 2164 O ATOM 1403 OP2 DG D 12 17.598 -17.813 6.417 1.00 54.81 O ANISOU 1403 OP2 DG D 12 6319 6788 7717 -517 -2221 1606 O ATOM 1404 O5' DG D 12 16.004 -19.318 7.659 1.00 58.34 O ANISOU 1404 O5' DG D 12 6116 7656 8394 -594 -2196 2056 O ATOM 1405 C5' DG D 12 15.753 -20.242 8.803 1.00 53.72 C ANISOU 1405 C5' DG D 12 5155 7420 7836 -665 -2078 2360 C ATOM 1406 C4' DG D 12 14.183 -20.515 8.840 1.00 64.01 C ANISOU 1406 C4' DG D 12 6164 8776 9382 -628 -2148 2489 C ATOM 1407 O4' DG D 12 13.494 -19.498 9.607 1.00 59.33 O ANISOU 1407 O4' DG D 12 5427 8487 8630 -471 -2024 2381 O ATOM 1408 C3' DG D 12 13.342 -20.568 7.584 1.00 68.60 C ANISOU 1408 C3' DG D 12 6859 8972 10235 -618 -2393 2423 C ATOM 1409 O3' DG D 12 12.234 -21.509 7.806 1.00 70.05 O ANISOU 1409 O3' DG D 12 6682 9221 10713 -686 -2463 2718 O ATOM 1410 C2' DG D 12 12.757 -19.150 7.393 1.00 67.13 C ANISOU 1410 C2' DG D 12 6776 8804 9925 -444 -2391 2115 C ATOM 1411 C1' DG D 12 12.485 -18.870 8.888 1.00 59.82 C ANISOU 1411 C1' DG D 12 5530 8389 8810 -374 -2152 2231 C ATOM 1412 N9 DG D 12 12.236 -17.493 9.334 1.00 72.25 N ANISOU 1412 N9 DG D 12 7181 10167 10103 -187 -2043 1994 N ATOM 1413 C8 DG D 12 12.882 -16.336 8.982 1.00 76.32 C ANISOU 1413 C8 DG D 12 8058 10578 10361 -109 -2046 1659 C ATOM 1414 N7 DG D 12 12.395 -15.260 9.538 1.00 73.44 N ANISOU 1414 N7 DG D 12 7705 10444 9755 68 -1951 1518 N ATOM 1415 C5 DG D 12 11.338 -15.716 10.305 1.00 85.36 C ANISOU 1415 C5 DG D 12 8824 12235 11376 133 -1862 1790 C ATOM 1416 C6 DG D 12 10.420 -15.006 11.125 1.00 80.88 C ANISOU 1416 C6 DG D 12 8104 11991 10638 351 -1723 1823 C ATOM 1417 O6 DG D 12 10.359 -13.787 11.354 1.00 82.80 O ANISOU 1417 O6 DG D 12 8563 12341 10558 533 -1665 1596 O ATOM 1418 N1 DG D 12 9.507 -15.868 11.736 1.00 74.95 N ANISOU 1418 N1 DG D 12 6914 11448 10116 362 -1639 2185 N ATOM 1419 C2 DG D 12 9.466 -17.234 11.566 1.00 80.34 C ANISOU 1419 C2 DG D 12 7345 12031 11148 164 -1704 2462 C ATOM 1420 N2 DG D 12 8.484 -17.908 12.212 1.00 88.08 N ANISOU 1420 N2 DG D 12 7891 13232 12341 197 -1606 2810 N ATOM 1421 N3 DG D 12 10.307 -17.901 10.787 1.00 79.81 N ANISOU 1421 N3 DG D 12 7453 11656 11214 -40 -1854 2418 N ATOM 1422 C4 DG D 12 11.223 -17.089 10.189 1.00 87.11 C ANISOU 1422 C4 DG D 12 8795 12380 11922 -34 -1917 2084 C ATOM 1423 P DT D 13 11.701 -22.290 6.532 1.00 82.23 P ANISOU 1423 P DT D 13 8346 10297 12603 -769 -2780 2795 P ATOM 1424 OP1 DT D 13 12.359 -23.617 6.617 1.00 90.40 O ANISOU 1424 OP1 DT D 13 9382 11267 13699 -929 -2798 3067 O ATOM 1425 OP2 DT D 13 11.815 -21.477 5.303 1.00 66.19 O ANISOU 1425 OP2 DT D 13 6727 7869 10553 -664 -2947 2472 O ATOM 1426 O5' DT D 13 10.141 -22.435 6.980 1.00 88.50 O ANISOU 1426 O5' DT D 13 8681 11284 13660 -759 -2813 2986 O ATOM 1427 C5' DT D 13 9.977 -22.726 8.419 1.00 83.67 C ANISOU 1427 C5' DT D 13 7662 11158 12972 -765 -2543 3231 C ATOM 1428 C4' DT D 13 8.662 -22.291 9.060 1.00 83.07 C ANISOU 1428 C4' DT D 13 7187 11370 13004 -649 -2450 3339 C ATOM 1429 O4' DT D 13 8.628 -20.913 9.559 1.00 81.62 O ANISOU 1429 O4' DT D 13 7071 11438 12502 -432 -2264 3097 O ATOM 1430 C3' DT D 13 7.467 -22.487 8.137 1.00 82.40 C ANISOU 1430 C3' DT D 13 6993 11006 13309 -684 -2738 3395 C ATOM 1431 O3' DT D 13 6.514 -23.057 8.956 1.00 86.21 O ANISOU 1431 O3' DT D 13 6974 11765 14017 -710 -2640 3750 O ATOM 1432 C2' DT D 13 7.109 -21.066 7.741 1.00 73.12 C ANISOU 1432 C2' DT D 13 5999 9814 11971 -482 -2743 3055 C ATOM 1433 C1' DT D 13 7.533 -20.249 8.971 1.00 76.36 C ANISOU 1433 C1' DT D 13 6359 10674 11979 -323 -2395 2991 C ATOM 1434 N1 DT D 13 7.875 -18.849 8.559 1.00 81.35 N ANISOU 1434 N1 DT D 13 7371 11241 12297 -156 -2382 2578 N ATOM 1435 C2 DT D 13 7.289 -17.742 9.174 1.00 84.44 C ANISOU 1435 C2 DT D 13 7692 11933 12459 69 -2212 2480 C ATOM 1436 O2 DT D 13 6.495 -17.770 10.095 1.00 86.53 O ANISOU 1436 O2 DT D 13 7596 12539 12744 174 -2043 2721 O ATOM 1437 N3 DT D 13 7.691 -16.537 8.668 1.00 83.29 N ANISOU 1437 N3 DT D 13 7950 11668 12027 192 -2234 2088 N ATOM 1438 C4 DT D 13 8.571 -16.330 7.625 1.00 79.23 C ANISOU 1438 C4 DT D 13 7866 10770 11468 123 -2388 1803 C ATOM 1439 O4 DT D 13 8.851 -15.207 7.244 1.00 80.01 O ANISOU 1439 O4 DT D 13 8302 10786 11314 246 -2383 1466 O ATOM 1440 C5 DT D 13 9.129 -17.515 7.019 1.00 79.58 C ANISOU 1440 C5 DT D 13 7957 10512 11767 -85 -2545 1942 C ATOM 1441 C7 DT D 13 10.081 -17.387 5.868 1.00 72.94 C ANISOU 1441 C7 DT D 13 7587 9233 10893 -127 -2693 1689 C ATOM 1442 C6 DT D 13 8.752 -18.708 7.498 1.00 75.55 C ANISOU 1442 C6 DT D 13 7078 10114 11512 -216 -2546 2314 C ATOM 1443 P DT D 14 5.207 -23.713 8.417 1.00 95.21 P ANISOU 1443 P DT D 14 7802 12718 15654 -815 -2906 3997 P ATOM 1444 OP1 DT D 14 5.063 -24.862 9.334 1.00102.07 O ANISOU 1444 OP1 DT D 14 8283 13813 16686 -947 -2768 4412 O ATOM 1445 OP2 DT D 14 5.210 -23.916 6.944 1.00 86.60 O ANISOU 1445 OP2 DT D 14 7057 11082 14763 -907 -3309 3832 O ATOM 1446 O5' DT D 14 4.146 -22.578 8.820 1.00 88.81 O ANISOU 1446 O5' DT D 14 6742 12192 14810 -584 -2765 3946 O ATOM 1447 C5' DT D 14 4.221 -22.205 10.195 1.00 83.28 C ANISOU 1447 C5' DT D 14 5821 11981 13839 -424 -2371 4062 C ATOM 1448 C4' DT D 14 3.149 -21.191 10.486 1.00 81.88 C ANISOU 1448 C4' DT D 14 5435 12041 13633 -183 -2257 4051 C ATOM 1449 O4' DT D 14 3.614 -19.903 10.052 1.00 83.34 O ANISOU 1449 O4' DT D 14 6058 12160 13446 -17 -2258 3610 O ATOM 1450 C3' DT D 14 1.786 -21.384 9.792 1.00 91.75 C ANISOU 1450 C3' DT D 14 6383 13128 15350 -225 -2508 4211 C ATOM 1451 O3' DT D 14 0.826 -21.111 10.749 1.00 87.80 O ANISOU 1451 O3' DT D 14 5439 13030 14890 -41 -2249 4494 O ATOM 1452 C2' DT D 14 1.692 -20.294 8.727 1.00 90.44 C ANISOU 1452 C2' DT D 14 6597 12708 15059 -108 -2706 3786 C ATOM 1453 C1' DT D 14 2.584 -19.230 9.374 1.00 83.08 C ANISOU 1453 C1' DT D 14 5984 12027 13554 95 -2410 3504 C ATOM 1454 N1 DT D 14 3.383 -18.449 8.442 1.00 80.99 N ANISOU 1454 N1 DT D 14 6277 11462 13035 123 -2551 3038 N ATOM 1455 C2 DT D 14 3.443 -17.080 8.567 1.00 79.28 C ANISOU 1455 C2 DT D 14 6310 11390 12422 364 -2411 2731 C ATOM 1456 O2 DT D 14 2.817 -16.455 9.424 1.00 79.08 O ANISOU 1456 O2 DT D 14 6082 11740 12225 580 -2179 2834 O ATOM 1457 N3 DT D 14 4.239 -16.494 7.608 1.00 71.12 N ANISOU 1457 N3 DT D 14 5793 10022 11206 357 -2558 2317 N ATOM 1458 C4 DT D 14 4.953 -17.124 6.579 1.00 79.07 C ANISOU 1458 C4 DT D 14 7087 10579 12378 169 -2805 2204 C ATOM 1459 O4 DT D 14 5.677 -16.520 5.772 1.00 71.54 O ANISOU 1459 O4 DT D 14 6601 9339 11241 204 -2890 1847 O ATOM 1460 C5 DT D 14 4.815 -18.563 6.541 1.00 79.75 C ANISOU 1460 C5 DT D 14 6902 10548 12853 -57 -2943 2555 C ATOM 1461 C7 DT D 14 5.499 -19.396 5.504 1.00 70.11 C ANISOU 1461 C7 DT D 14 5981 8847 11811 -238 -3213 2510 C ATOM 1462 C6 DT D 14 4.052 -19.141 7.465 1.00 84.75 C ANISOU 1462 C6 DT D 14 7025 11504 13670 -81 -2816 2940 C ATOM 1463 P DC D 15 -0.747 -21.341 10.561 1.00 99.48 P ANISOU 1463 P DC D 15 6399 14531 16866 -39 -2372 4823 P ATOM 1464 OP1 DC D 15 -1.053 -21.558 11.983 1.00 82.79 O ANISOU 1464 OP1 DC D 15 3875 12880 14702 102 -1968 5210 O ATOM 1465 OP2 DC D 15 -1.063 -22.295 9.466 1.00 91.88 O ANISOU 1465 OP2 DC D 15 5392 13122 16398 -334 -2814 4902 O ATOM 1466 O5' DC D 15 -1.427 -19.971 10.110 1.00 84.36 O ANISOU 1466 O5' DC D 15 4606 12653 14793 221 -2397 4555 O ATOM 1467 C5' DC D 15 -1.240 -18.842 10.929 1.00 81.21 C ANISOU 1467 C5' DC D 15 4350 12617 13889 538 -2048 4417 C ATOM 1468 C4' DC D 15 -1.616 -17.653 10.070 1.00 86.19 C ANISOU 1468 C4' DC D 15 5271 13116 14363 705 -2194 4042 C ATOM 1469 O4' DC D 15 -0.554 -17.339 9.131 1.00 86.07 O ANISOU 1469 O4' DC D 15 5841 12731 14132 605 -2403 3567 O ATOM 1470 C3' DC D 15 -2.855 -17.868 9.221 1.00 91.86 C ANISOU 1470 C3' DC D 15 5688 13638 15577 642 -2491 4171 C ATOM 1471 O3' DC D 15 -3.781 -16.831 9.513 1.00 94.36 O ANISOU 1471 O3' DC D 15 5868 14245 15738 957 -2318 4187 O ATOM 1472 C2' DC D 15 -2.319 -17.784 7.791 1.00 90.42 C ANISOU 1472 C2' DC D 15 5999 12927 15430 492 -2885 3736 C ATOM 1473 C1' DC D 15 -1.118 -16.867 7.942 1.00 86.79 C ANISOU 1473 C1' DC D 15 6093 12513 14370 627 -2699 3317 C ATOM 1474 N1 DC D 15 -0.092 -17.002 6.867 1.00 89.53 N ANISOU 1474 N1 DC D 15 6962 12387 14669 464 -2962 2950 N ATOM 1475 C2 DC D 15 0.547 -15.866 6.332 1.00 83.90 C ANISOU 1475 C2 DC D 15 6792 11541 13544 614 -2953 2464 C ATOM 1476 O2 DC D 15 0.227 -14.759 6.781 1.00 81.02 O ANISOU 1476 O2 DC D 15 6477 11464 12842 870 -2743 2337 O ATOM 1477 N3 DC D 15 1.501 -16.007 5.356 1.00 68.67 N ANISOU 1477 N3 DC D 15 5334 9172 11585 491 -3162 2166 N ATOM 1478 C4 DC D 15 1.786 -17.239 4.920 1.00 77.62 C ANISOU 1478 C4 DC D 15 6423 10008 13062 242 -3385 2346 C ATOM 1479 N4 DC D 15 2.695 -17.392 3.954 1.00 75.29 N ANISOU 1479 N4 DC D 15 6605 9274 12730 161 -3576 2089 N ATOM 1480 C5 DC D 15 1.131 -18.395 5.449 1.00 83.70 C ANISOU 1480 C5 DC D 15 6665 10906 14230 76 -3419 2822 C ATOM 1481 C6 DC D 15 0.221 -18.239 6.409 1.00 90.60 C ANISOU 1481 C6 DC D 15 7058 12211 15154 185 -3201 3109 C ATOM 1482 P DT D 16 -5.343 -17.079 9.803 1.00115.53 P ANISOU 1482 P DT D 16 7881 17146 18867 1040 -2286 4672 P ATOM 1483 OP1 DT D 16 -5.832 -15.778 10.322 1.00 98.17 O ANISOU 1483 OP1 DT D 16 5743 15312 16245 1447 -1989 4601 O ATOM 1484 OP2 DT D 16 -5.431 -18.242 10.722 1.00121.24 O ANISOU 1484 OP2 DT D 16 8125 18050 19889 899 -2120 5185 O ATOM 1485 O5' DT D 16 -5.993 -17.496 8.377 1.00 92.65 O ANISOU 1485 O5' DT D 16 4926 13775 16500 813 -2807 4591 O ATOM 1486 C5' DT D 16 -5.389 -18.550 7.589 1.00 83.55 C ANISOU 1486 C5' DT D 16 3933 12160 15653 457 -3172 4527 C ATOM 1487 C4' DT D 16 -5.371 -19.672 8.588 1.00 94.96 C ANISOU 1487 C4' DT D 16 4924 13822 17334 301 -2985 5026 C ATOM 1488 O4' DT D 16 -6.699 -19.796 9.148 1.00124.20 O ANISOU 1488 O4' DT D 16 7973 17822 21397 396 -2863 5507 O ATOM 1489 C3' DT D 16 -5.073 -21.110 8.216 1.00110.50 C ANISOU 1489 C3' DT D 16 6801 15455 19728 -77 -3279 5225 C ATOM 1490 O3' DT D 16 -3.683 -21.311 7.977 1.00111.89 O ANISOU 1490 O3' DT D 16 7512 15418 19584 -188 -3309 4914 O ATOM 1491 C2' DT D 16 -5.463 -21.760 9.557 1.00118.50 C ANISOU 1491 C2' DT D 16 7238 16894 20891 -66 -2919 5772 C ATOM 1492 C1' DT D 16 -6.532 -20.806 10.121 1.00129.08 C ANISOU 1492 C1' DT D 16 8236 18635 22173 271 -2645 5937 C ATOM 1493 N1 DT D 16 -7.826 -21.492 10.485 1.00137.26 N ANISOU 1493 N1 DT D 16 8531 19818 23803 209 -2643 6530 N ATOM 1494 C2 DT D 16 -8.434 -21.184 11.688 1.00144.17 C ANISOU 1494 C2 DT D 16 8987 21194 24598 497 -2177 6914 C ATOM 1495 O2 DT D 16 -8.010 -20.349 12.470 1.00149.96 O ANISOU 1495 O2 DT D 16 9950 22250 24779 816 -1785 6785 O ATOM 1496 N3 DT D 16 -9.573 -21.893 11.948 1.00144.86 N ANISOU 1496 N3 DT D 16 8382 21376 25282 411 -2190 7480 N ATOM 1497 C4 DT D 16 -10.144 -22.862 11.146 1.00146.10 C ANISOU 1497 C4 DT D 16 8236 21175 26100 46 -2651 7685 C ATOM 1498 O4 DT D 16 -11.183 -23.437 11.468 1.00154.24 O ANISOU 1498 O4 DT D 16 8612 22324 27670 -19 -2636 8224 O ATOM 1499 C5 DT D 16 -9.443 -23.137 9.910 1.00136.82 C ANISOU 1499 C5 DT D 16 7577 19467 24940 -234 -3151 7242 C ATOM 1500 C7 DT D 16 -9.954 -24.160 8.945 1.00140.27 C ANISOU 1500 C7 DT D 16 7821 19439 26034 -618 -3718 7405 C ATOM 1501 C6 DT D 16 -8.339 -22.449 9.640 1.00127.78 C ANISOU 1501 C6 DT D 16 7102 18235 23215 -128 -3107 6700 C TER 1502 DT D 16 ATOM 1503 O5' DA C 1 5.176 -16.305 -6.399 1.00 78.27 O ANISOU 1503 O5' DA C 1 6148 13468 10121 -1302 -3125 -1897 O ATOM 1504 C5' DA C 1 5.648 -15.283 -5.503 1.00 77.79 C ANISOU 1504 C5' DA C 1 6283 13402 9873 -880 -2732 -1832 C ATOM 1505 C4' DA C 1 5.497 -13.925 -6.207 1.00 77.18 C ANISOU 1505 C4' DA C 1 6206 13655 9466 -622 -2468 -1824 C ATOM 1506 O4' DA C 1 4.263 -13.861 -6.914 1.00 84.88 O ANISOU 1506 O4' DA C 1 6815 15061 10373 -766 -2516 -1462 O ATOM 1507 C3' DA C 1 5.516 -12.686 -5.309 1.00 75.12 C ANISOU 1507 C3' DA C 1 6116 13472 8956 -166 -2067 -1594 C ATOM 1508 O3' DA C 1 6.110 -11.555 -5.982 1.00 73.90 O ANISOU 1508 O3' DA C 1 6144 13358 8578 40 -1906 -1854 O ATOM 1509 C2' DA C 1 4.060 -12.373 -5.010 1.00 72.20 C ANISOU 1509 C2' DA C 1 5424 13547 8463 -47 -1897 -939 C ATOM 1510 C1' DA C 1 3.367 -13.360 -5.918 1.00 81.61 C ANISOU 1510 C1' DA C 1 6257 14904 9847 -508 -2239 -856 C ATOM 1511 N9 DA C 1 2.796 -14.428 -5.126 1.00 92.49 N ANISOU 1511 N9 DA C 1 7428 16235 11479 -719 -2425 -489 N ATOM 1512 C8 DA C 1 2.857 -15.777 -5.309 1.00100.82 C ANISOU 1512 C8 DA C 1 8397 17039 12872 -1168 -2846 -616 C ATOM 1513 N7 DA C 1 2.166 -16.465 -4.428 1.00105.15 N ANISOU 1513 N7 DA C 1 8701 17638 13613 -1274 -2933 -104 N ATOM 1514 C5 DA C 1 1.584 -15.499 -3.637 1.00 97.95 C ANISOU 1514 C5 DA C 1 7700 17084 12433 -827 -2520 398 C ATOM 1515 C6 DA C 1 0.715 -15.583 -2.546 1.00 91.94 C ANISOU 1515 C6 DA C 1 6665 16604 11665 -642 -2375 1109 C ATOM 1516 N6 DA C 1 0.227 -16.696 -1.958 1.00 84.97 N ANISOU 1516 N6 DA C 1 5482 15705 11098 -921 -2633 1526 N ATOM 1517 N1 DA C 1 0.406 -14.401 -2.035 1.00 96.14 N ANISOU 1517 N1 DA C 1 7269 17438 11824 -95 -1930 1392 N ATOM 1518 C2 DA C 1 0.869 -13.267 -2.560 1.00 82.60 C ANISOU 1518 C2 DA C 1 5853 15711 9818 182 -1688 1027 C ATOM 1519 N3 DA C 1 1.643 -13.032 -3.582 1.00 85.80 N ANISOU 1519 N3 DA C 1 6474 15902 10224 21 -1792 425 N ATOM 1520 C4 DA C 1 1.974 -14.233 -4.060 1.00 97.06 C ANISOU 1520 C4 DA C 1 7829 17063 11988 -478 -2209 136 C ATOM 1521 P DA C 2 7.115 -10.719 -5.082 1.00 83.90 P ANISOU 1521 P DA C 2 7838 14320 9722 366 -1708 -2014 P ATOM 1522 OP1 DA C 2 7.772 -9.734 -5.988 1.00 76.54 O ANISOU 1522 OP1 DA C 2 7031 13415 8635 466 -1647 -2275 O ATOM 1523 OP2 DA C 2 7.806 -11.696 -4.202 1.00 69.90 O ANISOU 1523 OP2 DA C 2 6208 12181 8171 240 -1858 -2171 O ATOM 1524 O5' DA C 2 6.227 -9.969 -3.987 1.00 67.45 O ANISOU 1524 O5' DA C 2 5801 12404 7425 752 -1400 -1518 O ATOM 1525 C5' DA C 2 5.258 -9.030 -4.301 1.00 67.50 C ANISOU 1525 C5' DA C 2 5676 12788 7183 1000 -1159 -1161 C ATOM 1526 C4' DA C 2 4.854 -8.445 -2.967 1.00 65.69 C ANISOU 1526 C4' DA C 2 5662 12558 6738 1452 -888 -815 C ATOM 1527 O4' DA C 2 3.907 -9.288 -2.238 1.00 60.29 O ANISOU 1527 O4' DA C 2 4676 12096 6137 1434 -890 -344 O ATOM 1528 C3' DA C 2 5.976 -8.154 -2.027 1.00 64.21 C ANISOU 1528 C3' DA C 2 5964 11916 6517 1621 -885 -1124 C ATOM 1529 O3' DA C 2 5.621 -6.880 -1.507 1.00 62.55 O ANISOU 1529 O3' DA C 2 6052 11758 5955 2128 -594 -916 O ATOM 1530 C2' DA C 2 5.917 -9.292 -0.980 1.00 60.85 C ANISOU 1530 C2' DA C 2 5446 11396 6279 1526 -984 -990 C ATOM 1531 C1' DA C 2 4.396 -9.591 -0.976 1.00 58.18 C ANISOU 1531 C1' DA C 2 4653 11552 5900 1584 -879 -376 C ATOM 1532 N9 DA C 2 4.051 -10.992 -0.735 1.00 78.03 N ANISOU 1532 N9 DA C 2 6805 14108 8733 1235 -1107 -187 N ATOM 1533 C8 DA C 2 4.681 -12.153 -1.136 1.00 76.10 C ANISOU 1533 C8 DA C 2 6471 13592 8852 751 -1447 -527 C ATOM 1534 N7 DA C 2 4.033 -13.238 -0.722 1.00 79.31 N ANISOU 1534 N7 DA C 2 6536 14100 9498 536 -1604 -166 N ATOM 1535 C5 DA C 2 2.948 -12.761 0.000 1.00 77.93 C ANISOU 1535 C5 DA C 2 6181 14333 9095 910 -1339 473 C ATOM 1536 C6 DA C 2 1.871 -13.362 0.698 1.00 80.96 C ANISOU 1536 C6 DA C 2 6151 15058 9551 942 -1332 1166 C ATOM 1537 N6 DA C 2 1.687 -14.675 0.837 1.00 78.54 N ANISOU 1537 N6 DA C 2 5528 14681 9634 520 -1647 1335 N ATOM 1538 N1 DA C 2 0.981 -12.540 1.287 1.00 70.10 N ANISOU 1538 N1 DA C 2 4702 14111 7820 1463 -985 1727 N ATOM 1539 C2 DA C 2 1.104 -11.223 1.192 1.00 85.82 C ANISOU 1539 C2 DA C 2 7043 16142 9421 1913 -678 1587 C ATOM 1540 N3 DA C 2 2.059 -10.552 0.556 1.00 87.60 N ANISOU 1540 N3 DA C 2 7673 16028 9582 1880 -686 958 N ATOM 1541 C4 DA C 2 2.944 -11.382 -0.016 1.00 83.03 C ANISOU 1541 C4 DA C 2 7111 15084 9350 1367 -1020 447 C ATOM 1542 P DG C 3 6.483 -6.218 -0.355 1.00 64.36 P ANISOU 1542 P DG C 3 6878 11563 6012 2445 -544 -1116 P ATOM 1543 OP1 DG C 3 6.203 -4.770 -0.495 1.00 67.94 O ANISOU 1543 OP1 DG C 3 7638 12041 6134 2861 -323 -1024 O ATOM 1544 OP2 DG C 3 7.866 -6.771 -0.348 1.00 66.91 O ANISOU 1544 OP2 DG C 3 7360 11480 6582 2091 -818 -1587 O ATOM 1545 O5' DG C 3 5.900 -6.513 1.076 1.00 58.44 O ANISOU 1545 O5' DG C 3 6197 10889 5120 2795 -397 -767 O ATOM 1546 C5' DG C 3 4.494 -6.280 1.319 1.00 69.98 C ANISOU 1546 C5' DG C 3 7422 12821 6346 3174 -124 -183 C ATOM 1547 C4' DG C 3 4.279 -6.673 2.768 1.00 77.81 C ANISOU 1547 C4' DG C 3 8510 13828 7227 3494 -35 74 C ATOM 1548 O4' DG C 3 3.788 -8.035 2.771 1.00 85.11 O ANISOU 1548 O4' DG C 3 8865 14998 8475 3135 -174 357 O ATOM 1549 C3' DG C 3 5.553 -6.717 3.593 1.00 88.42 C ANISOU 1549 C3' DG C 3 10327 14662 8607 3465 -188 -376 C ATOM 1550 O3' DG C 3 5.251 -6.728 4.962 1.00 89.13 O ANISOU 1550 O3' DG C 3 10591 14815 8458 3925 -37 -111 O ATOM 1551 C2' DG C 3 6.026 -8.117 3.273 1.00 90.36 C ANISOU 1551 C2' DG C 3 10184 14830 9320 2863 -467 -536 C ATOM 1552 C1' DG C 3 4.676 -8.767 3.554 1.00 92.83 C ANISOU 1552 C1' DG C 3 9983 15640 9649 2970 -347 96 C ATOM 1553 N9 DG C 3 4.670 -10.191 3.280 1.00 95.30 N ANISOU 1553 N9 DG C 3 9831 15975 10404 2435 -606 133 N ATOM 1554 C8 DG C 3 5.572 -10.890 2.510 1.00 82.90 C ANISOU 1554 C8 DG C 3 8226 14092 9181 1898 -900 -342 C ATOM 1555 N7 DG C 3 5.339 -12.168 2.492 1.00 75.17 N ANISOU 1555 N7 DG C 3 6860 13151 8551 1529 -1108 -199 N ATOM 1556 C5 DG C 3 4.221 -12.320 3.313 1.00 88.13 C ANISOU 1556 C5 DG C 3 8215 15179 10092 1808 -950 451 C ATOM 1557 C6 DG C 3 3.506 -13.481 3.696 1.00 76.50 C ANISOU 1557 C6 DG C 3 6254 13913 8900 1596 -1087 931 C ATOM 1558 O6 DG C 3 3.731 -14.638 3.364 1.00 72.06 O ANISOU 1558 O6 DG C 3 5464 13168 8749 1094 -1399 819 O ATOM 1559 N1 DG C 3 2.456 -13.215 4.555 1.00 79.03 N ANISOU 1559 N1 DG C 3 6360 14687 8979 2049 -839 1617 N ATOM 1560 C2 DG C 3 2.117 -11.960 4.983 1.00101.67 C ANISOU 1560 C2 DG C 3 9513 17767 11352 2685 -481 1780 C ATOM 1561 N2 DG C 3 1.065 -11.885 5.799 1.00104.89 N ANISOU 1561 N2 DG C 3 9654 18664 11536 3135 -255 2504 N ATOM 1562 N3 DG C 3 2.773 -10.856 4.646 1.00111.70 N ANISOU 1562 N3 DG C 3 11301 18781 12357 2887 -366 1293 N ATOM 1563 C4 DG C 3 3.808 -11.112 3.814 1.00100.24 C ANISOU 1563 C4 DG C 3 10003 16909 11174 2401 -621 663 C ATOM 1564 P DA C 4 5.363 -5.417 5.867 1.00 92.64 P ANISOU 1564 P DA C 4 11740 15068 8391 4600 153 -167 P ATOM 1565 OP1 DA C 4 4.559 -4.313 5.217 1.00 89.15 O ANISOU 1565 OP1 DA C 4 11387 14834 7651 4960 388 40 O ATOM 1566 OP2 DA C 4 6.790 -5.325 6.261 1.00 86.54 O ANISOU 1566 OP2 DA C 4 11443 13739 7698 4384 -95 -715 O ATOM 1567 O5' DA C 4 4.541 -5.844 7.170 1.00 84.74 O ANISOU 1567 O5' DA C 4 10610 14422 7165 5101 359 347 O ATOM 1568 C5' DA C 4 3.106 -5.699 7.066 1.00 96.44 C ANISOU 1568 C5' DA C 4 11722 16491 8431 5496 651 998 C ATOM 1569 C4' DA C 4 2.365 -6.469 8.150 1.00107.86 C ANISOU 1569 C4' DA C 4 12815 18363 9805 5809 782 1576 C ATOM 1570 O4' DA C 4 2.360 -7.886 7.835 1.00110.46 O ANISOU 1570 O4' DA C 4 12492 18806 10673 5153 546 1704 O ATOM 1571 C3' DA C 4 2.927 -6.341 9.559 1.00105.38 C ANISOU 1571 C3' DA C 4 12985 17831 9223 6244 810 1430 C ATOM 1572 O3' DA C 4 1.839 -6.165 10.479 1.00116.22 O ANISOU 1572 O3' DA C 4 14262 19732 10166 7008 1134 2087 O ATOM 1573 C2' DA C 4 3.696 -7.649 9.768 1.00109.11 C ANISOU 1573 C2' DA C 4 13137 18117 10202 5621 519 1238 C ATOM 1574 C1' DA C 4 2.999 -8.639 8.838 1.00106.08 C ANISOU 1574 C1' DA C 4 11975 18071 10262 5086 421 1597 C ATOM 1575 N9 DA C 4 3.889 -9.553 8.134 1.00100.82 N ANISOU 1575 N9 DA C 4 11122 17047 10137 4295 77 1154 N ATOM 1576 C8 DA C 4 5.027 -9.230 7.450 1.00 94.07 C ANISOU 1576 C8 DA C 4 10634 15696 9411 3932 -114 486 C ATOM 1577 N7 DA C 4 5.625 -10.260 6.903 1.00 84.72 N ANISOU 1577 N7 DA C 4 9176 14315 8698 3301 -389 237 N ATOM 1578 C5 DA C 4 4.824 -11.334 7.240 1.00 91.45 C ANISOU 1578 C5 DA C 4 9465 15504 9779 3198 -412 752 C ATOM 1579 C6 DA C 4 4.903 -12.712 6.967 1.00 84.20 C ANISOU 1579 C6 DA C 4 8091 14539 9363 2637 -675 798 C ATOM 1580 N6 DA C 4 5.871 -13.265 6.261 1.00 78.04 N ANISOU 1580 N6 DA C 4 7373 13363 8917 2114 -939 277 N ATOM 1581 N1 DA C 4 3.941 -13.515 7.451 1.00 85.98 N ANISOU 1581 N1 DA C 4 7795 15143 9730 2654 -670 1436 N ATOM 1582 C2 DA C 4 2.977 -12.963 8.177 1.00100.70 C ANISOU 1582 C2 DA C 4 9573 17465 11222 3243 -381 2015 C ATOM 1583 N3 DA C 4 2.789 -11.687 8.497 1.00109.49 N ANISOU 1583 N3 DA C 4 11104 18688 11808 3864 -84 2024 N ATOM 1584 C4 DA C 4 3.754 -10.914 7.999 1.00101.50 C ANISOU 1584 C4 DA C 4 10639 17230 10697 3790 -130 1351 C ATOM 1585 P DA C 5 2.047 -6.232 12.065 1.00120.21 P ANISOU 1585 P DA C 5 15084 20254 10336 7589 1222 2167 P ATOM 1586 OP1 DA C 5 1.372 -5.047 12.630 1.00123.19 O ANISOU 1586 OP1 DA C 5 15965 20826 10015 8556 1560 2404 O ATOM 1587 OP2 DA C 5 3.483 -6.500 12.356 1.00103.19 O ANISOU 1587 OP2 DA C 5 13302 17486 8420 7140 909 1478 O ATOM 1588 O5' DA C 5 1.252 -7.563 12.472 1.00136.74 O ANISOU 1588 O5' DA C 5 16301 22941 12714 7471 1253 2894 O ATOM 1589 C5' DA C 5 1.545 -8.774 11.777 1.00130.43 C ANISOU 1589 C5' DA C 5 14914 22053 12590 6581 951 2832 C ATOM 1590 C4' DA C 5 1.778 -9.955 12.698 1.00126.87 C ANISOU 1590 C4' DA C 5 14095 21689 12421 6422 831 3040 C ATOM 1591 O4' DA C 5 2.582 -10.912 11.961 1.00120.14 O ANISOU 1591 O4' DA C 5 13005 20439 12202 5520 472 2623 O ATOM 1592 C3' DA C 5 2.590 -9.679 13.953 1.00131.28 C ANISOU 1592 C3' DA C 5 15206 21998 12677 6841 866 2724 C ATOM 1593 O3' DA C 5 2.550 -10.843 14.774 1.00145.68 O ANISOU 1593 O3' DA C 5 16521 24057 14772 6736 805 3100 O ATOM 1594 C2' DA C 5 3.960 -9.598 13.305 1.00122.55 C ANISOU 1594 C2' DA C 5 14516 20184 11865 6202 567 1869 C ATOM 1595 C1' DA C 5 3.853 -10.932 12.565 1.00117.66 C ANISOU 1595 C1' DA C 5 13161 19634 11910 5431 342 2036 C ATOM 1596 N9 DA C 5 4.946 -11.232 11.643 1.00 98.94 N ANISOU 1596 N9 DA C 5 10914 16723 9954 4701 42 1379 N ATOM 1597 C8 DA C 5 5.884 -10.366 11.176 1.00 88.89 C ANISOU 1597 C8 DA C 5 10238 14981 8554 4606 -41 739 C ATOM 1598 N7 DA C 5 6.782 -10.924 10.384 1.00 90.95 N ANISOU 1598 N7 DA C 5 10434 14878 9244 3942 -309 297 N ATOM 1599 C5 DA C 5 6.391 -12.242 10.336 1.00 87.71 C ANISOU 1599 C5 DA C 5 9397 14664 9265 3584 -414 627 C ATOM 1600 C6 DA C 5 6.928 -13.343 9.672 1.00 82.10 C ANISOU 1600 C6 DA C 5 8386 13725 9084 2919 -687 411 C ATOM 1601 N6 DA C 5 8.027 -13.262 8.906 1.00 70.21 N ANISOU 1601 N6 DA C 5 7153 11791 7733 2529 -870 -187 N ATOM 1602 N1 DA C 5 6.294 -14.528 9.837 1.00 86.59 N ANISOU 1602 N1 DA C 5 8370 14524 10005 2698 -774 864 N ATOM 1603 C2 DA C 5 5.208 -14.592 10.609 1.00 82.64 C ANISOU 1603 C2 DA C 5 7549 14508 9344 3105 -592 1540 C ATOM 1604 N3 DA C 5 4.627 -13.617 11.290 1.00 92.65 N ANISOU 1604 N3 DA C 5 9026 16088 10090 3790 -296 1826 N ATOM 1605 C4 DA C 5 5.271 -12.457 11.110 1.00 93.40 C ANISOU 1605 C4 DA C 5 9764 15888 9835 4006 -221 1308 C ATOM 1606 P DC C 6 2.154 -10.891 16.337 1.00141.69 P ANISOU 1606 P DC C 6 15992 23997 13845 7535 1044 3605 P ATOM 1607 OP1 DC C 6 0.706 -10.550 16.393 1.00133.78 O ANISOU 1607 OP1 DC C 6 14644 23700 12488 8162 1355 4430 O ATOM 1608 OP2 DC C 6 3.155 -10.144 17.138 1.00132.58 O ANISOU 1608 OP2 DC C 6 15667 22420 12288 7894 1043 2989 O ATOM 1609 O5' DC C 6 2.409 -12.444 16.675 1.00128.51 O ANISOU 1609 O5' DC C 6 13636 22391 12800 6959 826 3852 O ATOM 1610 C5' DC C 6 1.642 -13.424 15.980 1.00133.95 C ANISOU 1610 C5' DC C 6 13520 23368 14007 6439 696 4395 C ATOM 1611 C4' DC C 6 2.384 -14.719 15.696 1.00128.59 C ANISOU 1611 C4' DC C 6 12495 22318 14044 5580 343 4155 C ATOM 1612 O4' DC C 6 3.260 -14.574 14.555 1.00117.06 O ANISOU 1612 O4' DC C 6 11390 20246 12841 4958 113 3372 O ATOM 1613 C3' DC C 6 3.224 -15.230 16.855 1.00135.64 C ANISOU 1613 C3' DC C 6 13474 23073 14990 5666 318 4012 C ATOM 1614 O3' DC C 6 2.593 -16.383 17.372 1.00138.30 O ANISOU 1614 O3' DC C 6 13036 23827 15685 5566 269 4764 O ATOM 1615 C2' DC C 6 4.585 -15.597 16.265 1.00128.29 C ANISOU 1615 C2' DC C 6 12847 21429 14467 4949 29 3187 C ATOM 1616 C1' DC C 6 4.506 -15.192 14.798 1.00116.86 C ANISOU 1616 C1' DC C 6 11531 19734 13135 4538 -92 2844 C ATOM 1617 N1 DC C 6 5.557 -14.228 14.431 1.00104.17 N ANISOU 1617 N1 DC C 6 10673 17619 11287 4518 -119 2045 N ATOM 1618 C2 DC C 6 6.633 -14.698 13.722 1.00 98.58 C ANISOU 1618 C2 DC C 6 10075 16397 10986 3859 -384 1463 C ATOM 1619 O2 DC C 6 6.639 -15.900 13.458 1.00100.65 O ANISOU 1619 O2 DC C 6 9854 16620 11768 3361 -574 1604 O ATOM 1620 N3 DC C 6 7.614 -13.835 13.365 1.00 99.68 N ANISOU 1620 N3 DC C 6 10839 16107 10930 3809 -435 810 N ATOM 1621 C4 DC C 6 7.498 -12.546 13.698 1.00 93.62 C ANISOU 1621 C4 DC C 6 10604 15363 9604 4367 -258 713 C ATOM 1622 N4 DC C 6 8.473 -11.708 13.331 1.00 90.36 N ANISOU 1622 N4 DC C 6 10788 14503 9041 4262 -361 114 N ATOM 1623 C5 DC C 6 6.388 -12.043 14.430 1.00 94.78 C ANISOU 1623 C5 DC C 6 10712 15994 9307 5083 22 1253 C ATOM 1624 C6 DC C 6 5.446 -12.917 14.772 1.00104.26 C ANISOU 1624 C6 DC C 6 11249 17675 10688 5148 97 1927 C ATOM 1625 P DA C 7 3.142 -17.062 18.699 1.00128.39 P ANISOU 1625 P DA C 7 11641 22640 14500 5739 291 4897 P ATOM 1626 OP1 DA C 7 2.140 -18.046 19.141 1.00138.52 O ANISOU 1626 OP1 DA C 7 12050 24502 16080 5757 282 5876 O ATOM 1627 OP2 DA C 7 3.599 -15.978 19.594 1.00139.69 O ANISOU 1627 OP2 DA C 7 13767 24066 15242 6476 535 4562 O ATOM 1628 O5' DA C 7 4.425 -17.884 18.218 1.00116.33 O ANISOU 1628 O5' DA C 7 10215 20419 13564 4899 -34 4212 O ATOM 1629 C5' DA C 7 4.280 -18.923 17.254 1.00101.21 C ANISOU 1629 C5' DA C 7 7833 18303 12318 4123 -339 4290 C ATOM 1630 C4' DA C 7 5.632 -19.559 16.959 1.00 91.73 C ANISOU 1630 C4' DA C 7 6864 16451 11537 3514 -578 3590 C ATOM 1631 O4' DA C 7 6.428 -18.591 16.233 1.00 81.98 O ANISOU 1631 O4' DA C 7 6326 14786 10038 3450 -581 2796 O ATOM 1632 C3' DA C 7 6.416 -19.979 18.188 1.00 91.15 C ANISOU 1632 C3' DA C 7 6810 16354 11471 3685 -508 3567 C ATOM 1633 O3' DA C 7 6.854 -21.341 18.104 1.00 95.73 O ANISOU 1633 O3' DA C 7 6988 16670 12714 3087 -752 3609 O ATOM 1634 C2' DA C 7 7.638 -19.060 18.233 1.00 96.95 C ANISOU 1634 C2' DA C 7 8333 16668 11835 3788 -455 2753 C ATOM 1635 C1' DA C 7 7.747 -18.577 16.794 1.00 90.19 C ANISOU 1635 C1' DA C 7 7772 15460 11037 3409 -594 2268 C ATOM 1636 N9 DA C 7 8.190 -17.198 16.732 1.00 97.00 N ANISOU 1636 N9 DA C 7 9343 16166 11345 3755 -475 1777 N ATOM 1637 C8 DA C 7 7.603 -16.136 17.360 1.00102.60 C ANISOU 1637 C8 DA C 7 10338 17199 11444 4470 -228 1972 C ATOM 1638 N7 DA C 7 8.177 -14.988 17.117 1.00100.44 N ANISOU 1638 N7 DA C 7 10755 16625 10781 4623 -213 1428 N ATOM 1639 C5 DA C 7 9.215 -15.332 16.265 1.00 95.44 C ANISOU 1639 C5 DA C 7 10238 15490 10535 3956 -454 883 C ATOM 1640 C6 DA C 7 10.196 -14.547 15.649 1.00 82.07 C ANISOU 1640 C6 DA C 7 9124 13340 8720 3752 -574 240 C ATOM 1641 N6 DA C 7 10.229 -13.220 15.853 1.00 68.34 N ANISOU 1641 N6 DA C 7 7991 11535 6440 4196 -485 31 N ATOM 1642 N1 DA C 7 11.091 -15.166 14.841 1.00 89.78 N ANISOU 1642 N1 DA C 7 10030 13948 10132 3119 -792 -130 N ATOM 1643 C2 DA C 7 10.990 -16.502 14.686 1.00 90.53 C ANISOU 1643 C2 DA C 7 9569 14080 10748 2729 -890 88 C ATOM 1644 N3 DA C 7 10.098 -17.352 15.228 1.00 72.68 N ANISOU 1644 N3 DA C 7 6753 12176 8686 2826 -828 673 N ATOM 1645 C4 DA C 7 9.241 -16.687 16.012 1.00 89.56 C ANISOU 1645 C4 DA C 7 8921 14725 10384 3447 -603 1069 C ATOM 1646 P DT C 8 7.794 -21.892 19.252 1.00105.56 P ANISOU 1646 P DT C 8 8219 17842 14047 3157 -697 3549 P ATOM 1647 OP1 DT C 8 7.687 -23.370 19.327 1.00105.46 O ANISOU 1647 OP1 DT C 8 7575 17774 14722 2690 -905 3958 O ATOM 1648 OP2 DT C 8 7.570 -21.022 20.426 1.00111.13 O ANISOU 1648 OP2 DT C 8 9112 19000 14114 3947 -391 3771 O ATOM 1649 O5' DT C 8 9.297 -21.615 18.763 1.00107.83 O ANISOU 1649 O5' DT C 8 9144 17498 14329 2820 -791 2629 O ATOM 1650 C5' DT C 8 9.872 -22.343 17.665 1.00 93.63 C ANISOU 1650 C5' DT C 8 7346 15190 13038 2142 -1058 2232 C ATOM 1651 C4' DT C 8 11.278 -21.829 17.395 1.00 93.15 C ANISOU 1651 C4' DT C 8 7900 14684 12808 2005 -1073 1469 C ATOM 1652 O4' DT C 8 11.211 -20.385 17.200 1.00 99.20 O ANISOU 1652 O4' DT C 8 9195 15504 12994 2363 -950 1182 O ATOM 1653 C3' DT C 8 12.256 -22.087 18.541 1.00 89.24 C ANISOU 1653 C3' DT C 8 7478 14167 12262 2125 -977 1413 C ATOM 1654 O3' DT C 8 13.494 -22.673 18.109 1.00 88.93 O ANISOU 1654 O3' DT C 8 7585 13668 12535 1663 -1116 963 O ATOM 1655 C2' DT C 8 12.469 -20.685 19.112 1.00 94.09 C ANISOU 1655 C2' DT C 8 8650 14913 12187 2639 -804 1188 C ATOM 1656 C1' DT C 8 12.366 -19.870 17.835 1.00 91.63 C ANISOU 1656 C1' DT C 8 8704 14366 11745 2490 -893 786 C ATOM 1657 N1 DT C 8 12.283 -18.392 18.030 1.00 92.68 N ANISOU 1657 N1 DT C 8 9404 14572 11238 2960 -772 580 N ATOM 1658 C2 DT C 8 13.126 -17.624 17.271 1.00 91.18 C ANISOU 1658 C2 DT C 8 9742 13996 10907 2753 -882 0 C ATOM 1659 O2 DT C 8 13.913 -18.092 16.456 1.00 83.55 O ANISOU 1659 O2 DT C 8 8773 12693 10280 2252 -1046 -324 O ATOM 1660 N3 DT C 8 13.014 -16.282 17.492 1.00 94.95 N ANISOU 1660 N3 DT C 8 10758 14499 10821 3182 -802 -162 N ATOM 1661 C4 DT C 8 12.165 -15.648 18.365 1.00 96.65 C ANISOU 1661 C4 DT C 8 11077 15076 10570 3833 -607 159 C ATOM 1662 O4 DT C 8 12.127 -14.429 18.479 1.00 87.72 O ANISOU 1662 O4 DT C 8 10511 13887 8932 4213 -561 -46 O ATOM 1663 C5 DT C 8 11.311 -16.506 19.128 1.00107.86 C ANISOU 1663 C5 DT C 8 11901 16952 12128 4068 -467 782 C ATOM 1664 C7 DT C 8 10.358 -15.877 20.101 1.00112.24 C ANISOU 1664 C7 DT C 8 12517 17987 12144 4858 -226 1207 C ATOM 1665 C6 DT C 8 11.408 -17.829 18.933 1.00105.88 C ANISOU 1665 C6 DT C 8 11077 16679 12472 3599 -566 978 C ATOM 1666 P DT C 9 14.372 -23.593 19.069 1.00111.84 P ANISOU 1666 P DT C 9 10282 16525 15688 1572 -1078 1070 P ATOM 1667 OP1 DT C 9 13.714 -24.915 19.234 1.00103.14 O ANISOU 1667 OP1 DT C 9 8533 15510 15145 1380 -1159 1599 O ATOM 1668 OP2 DT C 9 14.759 -22.810 20.269 1.00109.40 O ANISOU 1668 OP2 DT C 9 10234 16468 14864 2025 -889 1077 O ATOM 1669 O5' DT C 9 15.667 -23.719 18.136 1.00 99.30 O ANISOU 1669 O5' DT C 9 9054 14424 14251 1134 -1217 454 O ATOM 1670 C5' DT C 9 15.696 -22.815 17.026 1.00 90.54 C ANISOU 1670 C5' DT C 9 8354 13134 12911 1063 -1298 31 C ATOM 1671 C4' DT C 9 16.928 -21.908 17.046 1.00 88.57 C ANISOU 1671 C4' DT C 9 8654 12709 12291 1082 -1280 -437 C ATOM 1672 O4' DT C 9 16.520 -20.512 17.162 1.00 96.34 O ANISOU 1672 O4' DT C 9 10027 13839 12737 1439 -1215 -530 O ATOM 1673 C3' DT C 9 17.954 -22.154 18.151 1.00 86.10 C ANISOU 1673 C3' DT C 9 8376 12420 11917 1124 -1201 -407 C ATOM 1674 O3' DT C 9 19.089 -22.959 17.644 1.00 86.73 O ANISOU 1674 O3' DT C 9 8431 12188 12334 726 -1286 -627 O ATOM 1675 C2' DT C 9 18.329 -20.755 18.665 1.00 85.11 C ANISOU 1675 C2' DT C 9 8789 12363 11187 1418 -1162 -619 C ATOM 1676 C1' DT C 9 17.547 -19.773 17.800 1.00 92.40 C ANISOU 1676 C1' DT C 9 9967 13268 11872 1543 -1201 -772 C ATOM 1677 N1 DT C 9 16.903 -18.638 18.517 1.00 86.76 N ANISOU 1677 N1 DT C 9 9559 12790 10617 2056 -1098 -683 N ATOM 1678 C2 DT C 9 17.229 -17.360 18.146 1.00 83.52 C ANISOU 1678 C2 DT C 9 9726 12203 9805 2137 -1175 -1038 C ATOM 1679 O2 DT C 9 18.020 -17.100 17.272 1.00 88.99 O ANISOU 1679 O2 DT C 9 10641 12600 10571 1800 -1320 -1380 O ATOM 1680 N3 DT C 9 16.594 -16.376 18.839 1.00 79.59 N ANISOU 1680 N3 DT C 9 9548 11893 8800 2662 -1080 -954 N ATOM 1681 C4 DT C 9 15.660 -16.535 19.832 1.00 85.26 C ANISOU 1681 C4 DT C 9 10040 13010 9344 3148 -895 -531 C ATOM 1682 O4 DT C 9 15.129 -15.577 20.386 1.00 81.83 O ANISOU 1682 O4 DT C 9 9967 12732 8394 3679 -806 -489 O ATOM 1683 C5 DT C 9 15.355 -17.898 20.175 1.00 96.06 C ANISOU 1683 C5 DT C 9 10730 14601 11166 3020 -820 -120 C ATOM 1684 C7 DT C 9 14.352 -18.173 21.257 1.00111.84 C ANISOU 1684 C7 DT C 9 12374 17101 13019 3539 -621 440 C ATOM 1685 C6 DT C 9 15.981 -18.879 19.513 1.00 86.61 C ANISOU 1685 C6 DT C 9 9246 13162 10499 2467 -935 -224 C ATOM 1686 P DG C 10 20.677 -22.614 17.632 1.00 94.53 P ANISOU 1686 P DG C 10 9783 12987 13148 559 -1317 -958 P ATOM 1687 OP1 DG C 10 21.289 -23.828 17.038 1.00 74.88 O ANISOU 1687 OP1 DG C 10 7063 10262 11127 238 -1363 -997 O ATOM 1688 OP2 DG C 10 21.157 -22.100 18.936 1.00 84.12 O ANISOU 1688 OP2 DG C 10 8619 11868 11474 780 -1229 -853 O ATOM 1689 O5' DG C 10 20.779 -21.408 16.580 1.00 70.87 O ANISOU 1689 O5' DG C 10 7241 9843 9842 526 -1434 -1341 O ATOM 1690 C5' DG C 10 21.980 -20.783 16.426 1.00 63.75 C ANISOU 1690 C5' DG C 10 6695 8810 8716 397 -1509 -1591 C ATOM 1691 C4' DG C 10 22.169 -19.526 17.243 1.00 72.69 C ANISOU 1691 C4' DG C 10 8248 10034 9336 621 -1530 -1640 C ATOM 1692 O4' DG C 10 21.050 -19.122 18.044 1.00 81.21 O ANISOU 1692 O4' DG C 10 9330 11343 10182 1018 -1428 -1449 O ATOM 1693 C3' DG C 10 23.313 -19.650 18.227 1.00 73.20 C ANISOU 1693 C3' DG C 10 8383 10139 9292 546 -1531 -1568 C ATOM 1694 O3' DG C 10 24.380 -19.049 17.537 1.00 82.96 O ANISOU 1694 O3' DG C 10 9928 11185 10409 289 -1695 -1800 O ATOM 1695 C2' DG C 10 22.880 -18.880 19.484 1.00 73.12 C ANISOU 1695 C2' DG C 10 8613 10323 8846 919 -1495 -1466 C ATOM 1696 C1' DG C 10 21.567 -18.225 19.013 1.00 79.41 C ANISOU 1696 C1' DG C 10 9514 11158 9498 1202 -1467 -1504 C ATOM 1697 N9 DG C 10 20.507 -18.060 20.010 1.00 84.13 N ANISOU 1697 N9 DG C 10 10052 12051 9861 1679 -1322 -1248 N ATOM 1698 C8 DG C 10 19.838 -19.073 20.660 1.00 96.81 C ANISOU 1698 C8 DG C 10 11132 13936 11714 1833 -1153 -857 C ATOM 1699 N7 DG C 10 18.915 -18.666 21.493 1.00 96.10 N ANISOU 1699 N7 DG C 10 11063 14149 11303 2331 -1031 -624 N ATOM 1700 C5 DG C 10 18.977 -17.284 21.398 1.00 84.69 C ANISOU 1700 C5 DG C 10 10257 12572 9349 2534 -1125 -926 C ATOM 1701 C6 DG C 10 18.212 -16.292 22.063 1.00 84.94 C ANISOU 1701 C6 DG C 10 10653 12788 8833 3117 -1055 -876 C ATOM 1702 O6 DG C 10 17.313 -16.432 22.898 1.00 91.42 O ANISOU 1702 O6 DG C 10 11267 13991 9477 3609 -872 -519 O ATOM 1703 N1 DG C 10 18.572 -15.005 21.689 1.00 80.11 N ANISOU 1703 N1 DG C 10 10723 11879 7835 3142 -1223 -1264 N ATOM 1704 C2 DG C 10 19.548 -14.714 20.765 1.00 78.16 C ANISOU 1704 C2 DG C 10 10709 11251 7737 2640 -1439 -1605 C ATOM 1705 N2 DG C 10 19.757 -13.402 20.544 1.00 83.33 N ANISOU 1705 N2 DG C 10 12020 11648 7992 2728 -1612 -1905 N ATOM 1706 N3 DG C 10 20.270 -15.634 20.127 1.00 72.56 N ANISOU 1706 N3 DG C 10 9627 10429 7513 2125 -1484 -1623 N ATOM 1707 C4 DG C 10 19.940 -16.896 20.489 1.00 75.81 C ANISOU 1707 C4 DG C 10 9435 11079 8290 2110 -1319 -1300 C ATOM 1708 P DG C 11 25.812 -18.945 18.195 1.00 72.48 P ANISOU 1708 P DG C 11 8745 9861 8932 94 -1777 -1750 P ATOM 1709 OP1 DG C 11 26.724 -18.637 17.066 1.00 90.11 O ANISOU 1709 OP1 DG C 11 11114 11928 11197 -199 -1927 -1906 O ATOM 1710 OP2 DG C 11 26.047 -20.134 19.053 1.00 80.27 O ANISOU 1710 OP2 DG C 11 9326 11007 10166 91 -1609 -1480 O ATOM 1711 O5' DG C 11 25.773 -17.653 19.126 1.00 74.80 O ANISOU 1711 O5' DG C 11 9542 10181 8699 293 -1910 -1813 O ATOM 1712 C5' DG C 11 25.566 -16.451 18.387 1.00 78.30 C ANISOU 1712 C5' DG C 11 10411 10441 8900 307 -2084 -2053 C ATOM 1713 C4' DG C 11 25.029 -15.310 19.225 1.00 76.98 C ANISOU 1713 C4' DG C 11 10736 10266 8247 645 -2168 -2132 C ATOM 1714 O4' DG C 11 23.896 -15.804 19.970 1.00 75.74 O ANISOU 1714 O4' DG C 11 10334 10354 8089 1050 -1931 -1958 O ATOM 1715 C3' DG C 11 25.992 -14.798 20.266 1.00 77.90 C ANISOU 1715 C3' DG C 11 11215 10356 8029 568 -2361 -2121 C ATOM 1716 O3' DG C 11 26.723 -13.682 19.750 1.00 80.08 O ANISOU 1716 O3' DG C 11 11974 10360 8094 320 -2682 -2298 O ATOM 1717 C2' DG C 11 25.175 -14.463 21.530 1.00 76.13 C ANISOU 1717 C2' DG C 11 11211 10291 7426 1068 -2279 -2080 C ATOM 1718 C1' DG C 11 23.816 -15.056 21.188 1.00 82.42 C ANISOU 1718 C1' DG C 11 11597 11269 8449 1378 -1990 -1962 C ATOM 1719 N9 DG C 11 23.074 -15.885 22.145 1.00 84.13 N ANISOU 1719 N9 DG C 11 11413 11831 8723 1722 -1736 -1670 N ATOM 1720 C8 DG C 11 23.074 -17.258 22.277 1.00 91.01 C ANISOU 1720 C8 DG C 11 11640 12893 10046 1595 -1548 -1396 C ATOM 1721 N7 DG C 11 22.242 -17.719 23.178 1.00 87.38 N ANISOU 1721 N7 DG C 11 10890 12758 9552 1982 -1350 -1105 N ATOM 1722 C5 DG C 11 21.620 -16.570 23.637 1.00 89.34 C ANISOU 1722 C5 DG C 11 11636 13051 9256 2443 -1386 -1207 C ATOM 1723 C6 DG C 11 20.622 -16.433 24.621 1.00101.86 C ANISOU 1723 C6 DG C 11 13191 14989 10522 3051 -1215 -966 C ATOM 1724 O6 DG C 11 20.091 -17.344 25.283 1.00107.16 O ANISOU 1724 O6 DG C 11 13317 16026 11373 3261 -1005 -571 O ATOM 1725 N1 DG C 11 20.271 -15.087 24.795 1.00102.42 N ANISOU 1725 N1 DG C 11 13946 14960 10010 3448 -1314 -1196 N ATOM 1726 C2 DG C 11 20.834 -14.031 24.102 1.00 91.58 C ANISOU 1726 C2 DG C 11 13184 13166 8447 3219 -1574 -1597 C ATOM 1727 N2 DG C 11 20.379 -12.810 24.403 1.00 88.92 N ANISOU 1727 N2 DG C 11 13500 12737 7548 3676 -1653 -1775 N ATOM 1728 N3 DG C 11 21.768 -14.152 23.167 1.00 79.39 N ANISOU 1728 N3 DG C 11 11614 11319 7232 2615 -1747 -1781 N ATOM 1729 C4 DG C 11 22.108 -15.445 23.005 1.00 81.41 C ANISOU 1729 C4 DG C 11 11230 11700 8002 2283 -1626 -1572 C ATOM 1730 P DG C 12 27.884 -13.213 20.685 1.00 90.93 P ANISOU 1730 P DG C 12 13702 11677 9172 106 -2962 -2253 P ATOM 1731 OP1 DG C 12 29.077 -12.564 20.082 1.00 95.76 O ANISOU 1731 OP1 DG C 12 14547 12080 9758 -363 -3306 -2259 O ATOM 1732 OP2 DG C 12 28.162 -14.400 21.504 1.00 95.34 O ANISOU 1732 OP2 DG C 12 13797 12522 9905 104 -2745 -2011 O ATOM 1733 O5' DG C 12 27.080 -12.132 21.535 1.00 97.73 O ANISOU 1733 O5' DG C 12 15181 12437 9515 562 -3066 -2433 O ATOM 1734 C5' DG C 12 27.869 -11.047 22.048 1.00 82.76 C ANISOU 1734 C5' DG C 12 13935 10289 7220 403 -3480 -2548 C ATOM 1735 C4' DG C 12 27.160 -10.197 23.090 1.00 84.23 C ANISOU 1735 C4' DG C 12 14741 10401 6862 920 -3561 -2721 C ATOM 1736 O4' DG C 12 25.921 -10.819 23.555 1.00 88.90 O ANISOU 1736 O4' DG C 12 15017 11317 7446 1488 -3150 -2635 O ATOM 1737 C3' DG C 12 28.075 -10.081 24.285 1.00 86.64 C ANISOU 1737 C3' DG C 12 15335 10722 6862 783 -3818 -2675 C ATOM 1738 O3' DG C 12 27.960 -8.805 24.936 1.00 93.17 O ANISOU 1738 O3' DG C 12 17037 11245 7118 1030 -4166 -2931 O ATOM 1739 C2' DG C 12 27.606 -11.297 25.086 1.00 82.55 C ANISOU 1739 C2' DG C 12 14233 10665 6466 1092 -3404 -2453 C ATOM 1740 C1' DG C 12 26.099 -11.172 24.915 1.00 72.47 C ANISOU 1740 C1' DG C 12 12947 9474 5113 1697 -3112 -2523 C ATOM 1741 N9 DG C 12 25.364 -12.395 25.254 1.00 82.19 N ANISOU 1741 N9 DG C 12 13475 11141 6613 1980 -2678 -2247 N ATOM 1742 C8 DG C 12 25.711 -13.676 24.912 1.00 85.12 C ANISOU 1742 C8 DG C 12 13108 11708 7524 1650 -2470 -2002 C ATOM 1743 N7 DG C 12 24.875 -14.583 25.349 1.00 90.57 N ANISOU 1743 N7 DG C 12 13280 12750 8383 1985 -2132 -1753 N ATOM 1744 C5 DG C 12 23.903 -13.865 26.034 1.00 87.53 C ANISOU 1744 C5 DG C 12 13273 12469 7515 2608 -2085 -1803 C ATOM 1745 C6 DG C 12 22.751 -14.319 26.729 1.00 86.38 C ANISOU 1745 C6 DG C 12 12804 12732 7285 3196 -1775 -1533 C ATOM 1746 O6 DG C 12 22.340 -15.478 26.882 1.00 91.26 O ANISOU 1746 O6 DG C 12 12710 13676 8289 3232 -1503 -1185 O ATOM 1747 N1 DG C 12 22.028 -13.271 27.279 1.00 85.24 N ANISOU 1747 N1 DG C 12 13251 12602 6536 3808 -1809 -1660 N ATOM 1748 C2 DG C 12 22.391 -11.951 27.170 1.00 92.92 C ANISOU 1748 C2 DG C 12 15073 13170 7063 3818 -2134 -2044 C ATOM 1749 N2 DG C 12 21.582 -11.070 27.777 1.00103.03 N ANISOU 1749 N2 DG C 12 16901 14495 7750 4513 -2116 -2134 N ATOM 1750 N3 DG C 12 23.468 -11.513 26.527 1.00 90.93 N ANISOU 1750 N3 DG C 12 15122 12502 6926 3214 -2464 -2289 N ATOM 1751 C4 DG C 12 24.187 -12.518 25.979 1.00 86.64 C ANISOU 1751 C4 DG C 12 13965 12004 6949 2634 -2410 -2133 C ATOM 1752 P DT C 13 29.142 -8.378 25.890 1.00125.57 P ANISOU 1752 P DT C 13 21603 15216 10893 700 -4624 -2933 P ATOM 1753 OP1 DT C 13 30.045 -7.433 25.190 1.00126.88 O ANISOU 1753 OP1 DT C 13 22196 14943 11072 141 -5135 -2997 O ATOM 1754 OP2 DT C 13 29.695 -9.621 26.486 1.00128.70 O ANISOU 1754 OP2 DT C 13 21341 16046 11514 529 -4393 -2630 O ATOM 1755 O5' DT C 13 28.256 -7.592 26.970 1.00120.44 O ANISOU 1755 O5' DT C 13 21685 14483 9594 1421 -4677 -3197 O ATOM 1756 C5' DT C 13 26.936 -7.264 26.525 1.00117.63 C ANISOU 1756 C5' DT C 13 21425 14102 9167 1998 -4400 -3331 C ATOM 1757 C4' DT C 13 25.968 -7.088 27.677 1.00115.07 C ANISOU 1757 C4' DT C 13 21440 13981 8302 2827 -4217 -3414 C ATOM 1758 O4' DT C 13 25.241 -8.328 27.903 1.00112.86 O ANISOU 1758 O4' DT C 13 20322 14273 8289 3146 -3671 -3109 O ATOM 1759 C3' DT C 13 26.619 -6.721 29.001 1.00122.90 C ANISOU 1759 C3' DT C 13 23008 14922 8767 2897 -4559 -3525 C ATOM 1760 O3' DT C 13 25.707 -5.930 29.722 1.00124.33 O ANISOU 1760 O3' DT C 13 23894 15036 8310 3707 -4556 -3752 O ATOM 1761 C2' DT C 13 26.777 -8.087 29.657 1.00122.72 C ANISOU 1761 C2' DT C 13 22158 15485 8985 2884 -4201 -3184 C ATOM 1762 C1' DT C 13 25.440 -8.704 29.258 1.00115.33 C ANISOU 1762 C1' DT C 13 20643 14897 8279 3410 -3644 -3013 C ATOM 1763 N1 DT C 13 25.402 -10.184 29.323 1.00107.98 N ANISOU 1763 N1 DT C 13 18702 14471 7853 3288 -3230 -2624 N ATOM 1764 C2 DT C 13 24.255 -10.795 29.783 1.00117.15 C ANISOU 1764 C2 DT C 13 19428 16096 8988 3926 -2792 -2386 C ATOM 1765 O2 DT C 13 23.265 -10.178 30.150 1.00124.68 O ANISOU 1765 O2 DT C 13 20770 17115 9488 4629 -2695 -2460 O ATOM 1766 N3 DT C 13 24.310 -12.163 29.797 1.00112.82 N ANISOU 1766 N3 DT C 13 17964 15941 8963 3727 -2474 -2017 N ATOM 1767 C4 DT C 13 25.366 -12.953 29.396 1.00105.16 C ANISOU 1767 C4 DT C 13 16521 14938 8496 3023 -2520 -1893 C ATOM 1768 O4 DT C 13 25.291 -14.176 29.448 1.00100.99 O ANISOU 1768 O4 DT C 13 15215 14742 8414 2935 -2218 -1564 O ATOM 1769 C5 DT C 13 26.537 -12.240 28.927 1.00100.43 C ANISOU 1769 C5 DT C 13 16406 13899 7853 2428 -2954 -2134 C ATOM 1770 C7 DT C 13 27.762 -12.976 28.470 1.00 93.59 C ANISOU 1770 C7 DT C 13 15085 13019 7457 1701 -3020 -1965 C ATOM 1771 C6 DT C 13 26.502 -10.904 28.917 1.00 98.37 C ANISOU 1771 C6 DT C 13 17009 13252 7116 2561 -3301 -2471 C ATOM 1772 P DT C 14 26.070 -5.189 31.081 1.00144.30 P ANISOU 1772 P DT C 14 27333 17403 10092 4020 -4962 -4003 P ATOM 1773 OP1 DT C 14 25.596 -3.806 30.841 1.00142.03 O ANISOU 1773 OP1 DT C 14 28047 16557 9363 4379 -5256 -4375 O ATOM 1774 OP2 DT C 14 27.460 -5.441 31.565 1.00133.69 O ANISOU 1774 OP2 DT C 14 25963 16022 8810 3315 -5351 -3934 O ATOM 1775 O5' DT C 14 25.089 -5.956 32.086 1.00128.11 O ANISOU 1775 O5' DT C 14 24873 16022 7782 4870 -4431 -3794 O ATOM 1776 C5' DT C 14 23.734 -6.210 31.706 1.00118.05 C ANISOU 1776 C5' DT C 14 23212 15055 6585 5508 -3910 -3633 C ATOM 1777 C4' DT C 14 22.972 -6.607 32.970 1.00123.32 C ANISOU 1777 C4' DT C 14 23771 16304 6782 6385 -3578 -3454 C ATOM 1778 O4' DT C 14 22.900 -8.052 33.082 1.00120.16 O ANISOU 1778 O4' DT C 14 22237 16513 6906 6232 -3151 -2987 O ATOM 1779 C3' DT C 14 23.546 -6.167 34.310 1.00130.95 C ANISOU 1779 C3' DT C 14 25441 17241 7071 6638 -3921 -3666 C ATOM 1780 O3' DT C 14 22.458 -6.132 35.218 1.00137.10 O ANISOU 1780 O3' DT C 14 26337 18478 7276 7715 -3588 -3564 O ATOM 1781 C2' DT C 14 24.495 -7.312 34.663 1.00124.19 C ANISOU 1781 C2' DT C 14 23801 16737 6650 6007 -3880 -3374 C ATOM 1782 C1' DT C 14 23.667 -8.502 34.177 1.00119.47 C ANISOU 1782 C1' DT C 14 22071 16679 6641 6135 -3262 -2911 C ATOM 1783 N1 DT C 14 24.469 -9.638 33.670 1.00115.78 N ANISOU 1783 N1 DT C 14 20705 16349 6937 5305 -3165 -2628 N ATOM 1784 C2 DT C 14 23.923 -10.901 33.694 1.00111.24 C ANISOU 1784 C2 DT C 14 19117 16330 6818 5430 -2669 -2173 C ATOM 1785 O2 DT C 14 22.805 -11.128 34.129 1.00107.46 O ANISOU 1785 O2 DT C 14 18397 16279 6155 6169 -2315 -1944 O ATOM 1786 N3 DT C 14 24.747 -11.881 33.195 1.00111.44 N ANISOU 1786 N3 DT C 14 18433 16393 7515 4667 -2622 -1962 N ATOM 1787 C4 DT C 14 26.030 -11.721 32.690 1.00110.54 C ANISOU 1787 C4 DT C 14 18482 15891 7627 3849 -2982 -2114 C ATOM 1788 O4 DT C 14 26.694 -12.670 32.267 1.00106.86 O ANISOU 1788 O4 DT C 14 17343 15525 7734 3275 -2875 -1876 O ATOM 1789 C5 DT C 14 26.529 -10.361 32.696 1.00110.91 C ANISOU 1789 C5 DT C 14 19551 15409 7182 3738 -3504 -2536 C ATOM 1790 C7 DT C 14 27.899 -10.029 32.181 1.00107.48 C ANISOU 1790 C7 DT C 14 19346 14560 6930 2868 -3962 -2644 C ATOM 1791 C6 DT C 14 25.735 -9.400 33.180 1.00113.00 C ANISOU 1791 C6 DT C 14 20557 15564 6812 4448 -3584 -2791 C ATOM 1792 P DC C 15 22.499 -5.522 36.678 1.00151.65 P ANISOU 1792 P DC C 15 29040 20394 8188 8444 -3817 -3801 P ATOM 1793 OP1 DC C 15 21.263 -4.719 36.784 1.00149.91 O ANISOU 1793 OP1 DC C 15 29415 20175 7371 9496 -3626 -3911 O ATOM 1794 OP2 DC C 15 23.828 -4.943 37.018 1.00154.30 O ANISOU 1794 OP2 DC C 15 30107 20198 8320 7795 -4488 -4174 O ATOM 1795 O5' DC C 15 22.342 -6.833 37.583 1.00146.20 O ANISOU 1795 O5' DC C 15 27360 20572 7617 8705 -3371 -3301 O ATOM 1796 C5' DC C 15 21.360 -7.785 37.201 1.00135.93 C ANISOU 1796 C5' DC C 15 25020 19845 6781 8978 -2766 -2786 C ATOM 1797 C4' DC C 15 21.650 -9.123 37.850 1.00133.77 C ANISOU 1797 C4' DC C 15 23736 20226 6863 8810 -2484 -2317 C ATOM 1798 O4' DC C 15 22.715 -9.780 37.138 1.00127.08 O ANISOU 1798 O4' DC C 15 22366 19145 6775 7700 -2626 -2274 O ATOM 1799 C3' DC C 15 22.103 -9.069 39.298 1.00145.35 C ANISOU 1799 C3' DC C 15 25542 21995 7691 9202 -2635 -2374 C ATOM 1800 O3' DC C 15 21.113 -9.748 40.032 1.00149.64 O ANISOU 1800 O3' DC C 15 25440 23340 8076 10051 -2128 -1880 O ATOM 1801 C2' DC C 15 23.441 -9.814 39.319 1.00141.51 C ANISOU 1801 C2' DC C 15 24580 21468 7720 8200 -2830 -2297 C ATOM 1802 C1' DC C 15 23.385 -10.623 38.032 1.00133.92 C ANISOU 1802 C1' DC C 15 22736 20437 7710 7521 -2578 -2026 C ATOM 1803 N1 DC C 15 24.701 -10.884 37.402 1.00135.67 N ANISOU 1803 N1 DC C 15 22808 20270 8468 6420 -2879 -2117 N ATOM 1804 C2 DC C 15 25.051 -12.181 36.993 1.00131.42 C ANISOU 1804 C2 DC C 15 21210 20007 8715 5854 -2594 -1706 C ATOM 1805 O2 DC C 15 24.253 -13.108 37.174 1.00133.92 O ANISOU 1805 O2 DC C 15 20724 20856 9306 6228 -2129 -1275 O ATOM 1806 N3 DC C 15 26.258 -12.389 36.408 1.00123.31 N ANISOU 1806 N3 DC C 15 20070 18660 8123 4924 -2848 -1759 N ATOM 1807 C4 DC C 15 27.086 -11.357 36.233 1.00123.10 C ANISOU 1807 C4 DC C 15 20890 18084 7800 4518 -3384 -2156 C ATOM 1808 N4 DC C 15 28.270 -11.586 35.664 1.00117.26 N ANISOU 1808 N4 DC C 15 19969 17104 7481 3627 -3618 -2115 N ATOM 1809 C5 DC C 15 26.744 -10.033 36.640 1.00133.14 C ANISOU 1809 C5 DC C 15 23251 19020 8317 5022 -3723 -2584 C ATOM 1810 C6 DC C 15 25.554 -9.838 37.216 1.00136.79 C ANISOU 1810 C6 DC C 15 23867 19782 8323 5989 -3446 -2574 C ATOM 1811 P DC C 16 20.976 -9.627 41.615 1.00169.21 P ANISOU 1811 P DC C 16 28230 26361 9700 10960 -2100 -1832 P ATOM 1812 OP1 DC C 16 19.560 -9.290 41.894 1.00169.34 O ANISOU 1812 OP1 DC C 16 28353 26796 9194 12151 -1732 -1618 O ATOM 1813 OP2 DC C 16 22.057 -8.779 42.183 1.00169.33 O ANISOU 1813 OP2 DC C 16 29295 25882 9159 10703 -2703 -2403 O ATOM 1814 O5' DC C 16 21.290 -11.138 42.049 1.00167.85 O ANISOU 1814 O5' DC C 16 26773 26871 10130 10613 -1767 -1230 O ATOM 1815 C5' DC C 16 21.034 -12.211 41.131 1.00155.97 C ANISOU 1815 C5' DC C 16 24165 25510 9587 10070 -1426 -774 C ATOM 1816 C4' DC C 16 21.698 -13.500 41.590 1.00151.53 C ANISOU 1816 C4' DC C 16 22623 25395 9556 9584 -1263 -343 C ATOM 1817 O4' DC C 16 22.944 -13.733 40.874 1.00146.89 O ANISOU 1817 O4' DC C 16 21985 24283 9545 8445 -1551 -561 O ATOM 1818 C3' DC C 16 22.091 -13.537 43.063 1.00146.79 C ANISOU 1818 C3' DC C 16 22165 25282 8329 10050 -1316 -291 C ATOM 1819 O3' DC C 16 22.134 -14.889 43.480 1.00146.21 O ANISOU 1819 O3' DC C 16 20918 25848 8788 9921 -953 335 O ATOM 1820 C2' DC C 16 23.496 -12.962 42.991 1.00143.06 C ANISOU 1820 C2' DC C 16 22426 24183 7745 9246 -1871 -831 C ATOM 1821 C1' DC C 16 23.990 -13.814 41.834 1.00141.61 C ANISOU 1821 C1' DC C 16 21469 23746 8588 8232 -1780 -636 C ATOM 1822 N1 DC C 16 25.215 -13.346 41.153 1.00135.23 N ANISOU 1822 N1 DC C 16 21169 22240 7974 7270 -2255 -1051 N ATOM 1823 C2 DC C 16 26.031 -14.306 40.557 1.00128.53 C ANISOU 1823 C2 DC C 16 19561 21350 7925 6381 -2182 -802 C ATOM 1824 O2 DC C 16 25.695 -15.497 40.654 1.00123.13 O ANISOU 1824 O2 DC C 16 17869 21164 7753 6429 -1747 -288 O ATOM 1825 N3 DC C 16 27.152 -13.890 39.907 1.00124.59 N ANISOU 1825 N3 DC C 16 19463 20277 7596 5528 -2600 -1098 N ATOM 1826 C4 DC C 16 27.449 -12.587 39.844 1.00121.28 C ANISOU 1826 C4 DC C 16 20136 19315 6631 5494 -3104 -1612 C ATOM 1827 N4 DC C 16 28.562 -12.222 39.197 1.00111.92 N ANISOU 1827 N4 DC C 16 19256 17612 5656 4624 -3526 -1807 N ATOM 1828 C5 DC C 16 26.615 -11.598 40.449 1.00128.22 C ANISOU 1828 C5 DC C 16 21849 20160 6710 6380 -3205 -1916 C ATOM 1829 C6 DC C 16 25.516 -12.017 41.086 1.00131.75 C ANISOU 1829 C6 DC C 16 21898 21209 6951 7274 -2754 -1625 C TER 1830 DC C 16 HETATM 1831 ZN ZN A 526 17.323 -19.761 -0.343 1.00 57.47 ZN ANISOU 1831 ZN ZN A 526 4762 5038 12036 99 -567 -1017 ZN HETATM 1832 ZN ZN A 527 31.341 -14.257 3.548 1.00 38.20 ZN ANISOU 1832 ZN ZN A 527 4378 4122 6014 -69 313 355 ZN HETATM 1833 ZN ZN B 526 36.369 -13.033 22.816 1.00 88.83 ZN ANISOU 1833 ZN ZN B 526 14101 10853 8796 -2383 -2041 511 ZN HETATM 1834 ZN ZN B 527 35.130 -20.281 9.415 1.00 43.41 ZN ANISOU 1834 ZN ZN B 527 5721 5034 5738 -1074 -124 1025 ZN HETATM 1835 O HOH A 2 35.009 -16.914 2.371 1.00 39.31 O HETATM 1836 O HOH A 3 32.600 -17.263 7.068 1.00 46.22 O HETATM 1837 O HOH A 5 21.679 -14.911 6.724 1.00 50.85 O HETATM 1838 O HOH A 7 31.495 -19.350 7.873 1.00 41.47 O HETATM 1839 O HOH A 8 15.841 -13.389 7.649 1.00 54.56 O HETATM 1840 O HOH A 9 30.813 -10.757 0.685 1.00 56.86 O HETATM 1841 O HOH A 11 8.885 -11.596 -8.262 1.00 60.55 O HETATM 1842 O HOH A 16 20.535 -9.116 8.357 1.00 63.20 O HETATM 1843 O HOH A 17 28.579 -11.239 7.198 1.00 52.70 O HETATM 1844 O HOH A 18 27.066 -8.177 0.489 1.00 44.47 O HETATM 1845 O HOH A 22 8.835 -10.338 2.129 1.00 69.41 O HETATM 1846 O HOH A 25 32.938 -7.511 4.055 1.00 68.41 O HETATM 1847 O HOH A 26 15.399 -15.493 6.490 1.00 52.78 O HETATM 1848 O HOH A 27 32.381 -20.426 -3.121 1.00 64.50 O HETATM 1849 O HOH A 28 7.708 -19.141 2.063 1.00 66.14 O HETATM 1850 O HOH A 29 14.692 -17.349 -11.219 1.00 62.99 O HETATM 1851 O HOH A 30 28.701 -17.206 -2.229 1.00 74.17 O HETATM 1852 O HOH A 32 18.541 -9.221 6.337 1.00 49.27 O HETATM 1853 O HOH A 34 8.051 -6.760 -6.586 1.00 58.44 O HETATM 1854 O HOH A 38 25.134 -20.671 -1.987 1.00 70.34 O HETATM 1855 O HOH A 39 28.960 -27.880 0.191 1.00 55.09 O HETATM 1856 O HOH A 40 10.674 -22.189 0.606 1.00 59.96 O HETATM 1857 O HOH A 43 36.879 -9.640 3.510 1.00 66.41 O HETATM 1858 O HOH A 44 7.108 -16.682 3.318 1.00 69.61 O HETATM 1859 O HOH A 45 35.610 -8.541 5.166 1.00 70.96 O HETATM 1860 O HOH A 46 27.589 -19.648 -2.611 1.00 59.13 O HETATM 1861 O HOH A 47 36.886 -8.187 -1.086 1.00 58.78 O HETATM 1862 O HOH A 49 34.683 -19.590 -4.284 1.00 72.03 O HETATM 1863 O HOH A 54 10.884 -8.233 -12.642 1.00 69.37 O HETATM 1864 O HOH A 56 25.917 -19.117 12.253 1.00 75.07 O HETATM 1865 O HOH A 60 21.358 -23.023 -6.115 1.00 76.70 O HETATM 1866 O HOH A 61 18.611 -2.963 8.735 1.00 72.88 O HETATM 1867 O HOH A 62 13.135 -8.900 -12.167 1.00 51.34 O HETATM 1868 O HOH A 63 15.320 -4.305 7.585 1.00 75.02 O HETATM 1869 O HOH A 65 23.519 -15.906 -7.045 1.00 65.74 O HETATM 1870 O HOH A 66 21.509 -23.481 -8.558 1.00 77.21 O HETATM 1871 O HOH A 67 36.951 -15.996 -4.272 1.00 68.89 O HETATM 1872 O HOH A 68 26.833 -6.534 2.631 1.00 52.91 O HETATM 1873 O HOH A 75 31.511 -12.327 -6.768 1.00 79.82 O HETATM 1874 O HOH A 78 6.992 -2.968 1.769 1.00 74.70 O HETATM 1875 O HOH A 79 28.456 -5.132 3.455 1.00 72.51 O HETATM 1876 O HOH A 80 27.559 -22.684 11.356 1.00 60.36 O HETATM 1877 O HOH A 81 33.106 -14.037 -5.118 1.00 75.26 O HETATM 1878 O HOH A 82 25.966 -23.432 0.052 1.00 63.21 O HETATM 1879 O HOH A 83 29.552 -21.705 -3.052 1.00 66.98 O HETATM 1880 O HOH B 1 31.559 -14.371 7.439 1.00 45.00 O HETATM 1881 O HOH B 4 30.198 -22.157 11.533 1.00 46.60 O HETATM 1882 O HOH B 10 37.392 -18.166 3.203 1.00 38.94 O HETATM 1883 O HOH B 12 40.721 -18.506 12.166 1.00 52.53 O HETATM 1884 O HOH B 13 42.834 -22.938 5.178 1.00 47.99 O HETATM 1885 O HOH B 15 37.725 -19.237 6.318 1.00 42.22 O HETATM 1886 O HOH B 19 43.702 -20.403 3.629 1.00 63.14 O HETATM 1887 O HOH B 20 35.060 -25.963 15.121 1.00 56.38 O HETATM 1888 O HOH B 21 37.128 -23.904 11.532 1.00 54.71 O HETATM 1889 O HOH B 23 34.342 -26.536 9.329 1.00 53.13 O HETATM 1890 O HOH B 31 29.718 -17.278 17.308 1.00 67.91 O HETATM 1891 O HOH B 33 41.957 -14.942 12.974 1.00 63.58 O HETATM 1892 O HOH B 37 42.785 -22.058 10.709 1.00 57.29 O HETATM 1893 O HOH B 42 41.043 -14.199 16.891 1.00 70.98 O HETATM 1894 O HOH B 48 41.731 -17.577 3.964 1.00 71.73 O HETATM 1895 O HOH B 50 43.516 -13.785 16.822 1.00 78.48 O HETATM 1896 O HOH B 52 25.476 -28.137 15.109 1.00 71.81 O HETATM 1897 O HOH B 58 26.509 -13.806 11.599 1.00 67.56 O HETATM 1898 O HOH B 59 44.684 -22.021 6.901 1.00 53.62 O HETATM 1899 O HOH B 64 35.011 -27.726 11.496 1.00 71.82 O HETATM 1900 O HOH B 72 26.392 -17.773 23.367 1.00 70.01 O HETATM 1901 O HOH B 73 24.962 -11.391 12.186 1.00 80.45 O HETATM 1902 O HOH B 74 44.699 -16.290 13.561 1.00 75.74 O HETATM 1903 O HOH B 76 39.477 -17.148 4.939 1.00 64.27 O HETATM 1904 O HOH B 77 37.141 -31.888 28.968 1.00 86.98 O HETATM 1905 O HOH D 17 5.003 -18.068 12.416 1.00 70.10 O HETATM 1906 O HOH D 18 18.021 -9.987 8.510 1.00 50.16 O HETATM 1907 O HOH D 35 10.248 -19.649 13.573 1.00 67.60 O HETATM 1908 O HOH D 36 9.027 -20.683 4.704 1.00 71.72 O HETATM 1909 O HOH D 41 9.755 -21.515 2.457 1.00 62.80 O HETATM 1910 O HOH D 51 17.923 -12.012 8.534 1.00 65.90 O HETATM 1911 O HOH D 53 17.056 -7.679 13.190 1.00 79.05 O HETATM 1912 O HOH D 55 12.885 -21.266 3.123 1.00 67.26 O HETATM 1913 O HOH D 57 17.214 -8.030 9.870 1.00 66.24 O HETATM 1914 O HOH D 69 23.555 -14.163 10.964 1.00 61.67 O HETATM 1915 O HOH D 71 3.603 -22.093 5.764 1.00 78.24 O HETATM 1916 O HOH D 84 19.051 -21.970 9.517 1.00 71.67 O HETATM 1917 O HOH C 24 25.723 -17.710 14.539 1.00 74.36 O HETATM 1918 O HOH C 70 28.079 -15.856 23.414 1.00 70.28 O CONECT 30 1831 CONECT 51 1831 CONECT 155 1831 CONECT 171 1831 CONECT 315 1832 CONECT 368 1832 CONECT 454 1832 CONECT 472 1832 CONECT 642 1833 CONECT 663 1833 CONECT 761 1833 CONECT 777 1833 CONECT 913 1834 CONECT 955 1834 CONECT 1041 1834 CONECT 1059 1834 CONECT 1831 30 51 155 171 CONECT 1832 315 368 454 472 CONECT 1833 642 663 761 777 CONECT 1834 913 955 1041 1059 MASTER 501 0 4 7 4 0 4 6 1889 4 20 18 END
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Entry Information
PDB ID
3g8u
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Glucocorticoid receptor DNA binding domain
Ligand Name
16-mer
EC.Number
E.C.-.-.-.-
Resolution
1.9(Å)
Affinity (Kd/Ki/IC50)
Kd=0.89uM
Release Year
2009
Protein/NA Sequence
Check fasta file
Primary Reference
(2009) Science Vol. 324: pp. 407-410
Links to External Databases
RCSB PDB
The mother database
PDBsum
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Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P06536
Entrez Gene ID
NCBI Entrez Gene ID:
24413
ASD
Information of known allosteric effects of PDB entries
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