Browse entries in the PDBbind-CN Database
HEADER CELL INVASION 07-JUL-11 3SRI TITLE CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM AMA1 IN COMPLEX WITH A 29AA TITLE 2 PFRON2 PEPTIDE COMPND MOL_ID: 1; COMPND 2 MOLECULE: APICAL MEMBRANE ANTIGEN 1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: AMA1; COMPND 5 SYNONYM: MEROZOITE SURFACE ANTIGEN; COMPND 6 ENGINEERED: YES; COMPND 7 MUTATION: YES; COMPND 8 MOL_ID: 2; COMPND 9 MOLECULE: RHOPTRY NECK PROTEIN 2; COMPND 10 CHAIN: B; COMPND 11 FRAGMENT: RON2; COMPND 12 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM; SOURCE 3 ORGANISM_TAXID: 5835; SOURCE 4 STRAIN: CAMP/MALAYSIA; SOURCE 5 GENE: AMA-1, PF83; SOURCE 6 EXPRESSION_SYSTEM: PICHIA PASTORIS; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 4922; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: PLASMODIUM FALCIPARUM; SOURCE 11 ORGANISM_TAXID: 36329 KEYWDS AMA1, PLASMODIUM FALCIPARUM, RON2, MALARIA, CELL INVASION EXPDTA X-RAY DIFFRACTION AUTHOR B.VULLIEZ-LE NORMAND,F.A.SAUL,G.A.BENTLEY REVDAT 1 11-JUL-12 3SRI 0 JRNL AUTH B.VULLIEZ-LE NORMAND,M.L.TONKIN,M.H.LAMARQUE,S.LANGER, JRNL AUTH 2 S.HOOS,M.ROQUES,F.A.SAUL,B.W.FABER,G.A.BENTLEY, JRNL AUTH 3 M.J.BOULANGER,M.LEBRUN JRNL TITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE MALARIA PARASITE JRNL TITL 2 MOVING JUNCTION COMPLEX. JRNL REF PLOS PATHOG. V. 8 02755 2012 JRNL REFN ISSN 1553-7366 JRNL PMID 22737069 JRNL DOI 10.1371/JOURNAL.PPAT.1002755 REMARK 2 REMARK 2 RESOLUTION. 1.60 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : BUSTER 2.9.3 REMARK 3 AUTHORS : BRICOGNE,BLANC,BRANDL,FLENSBURG,KELLER, REMARK 3 : PACIOREK,ROVERSI,SHARFF,SMART,VONRHEIN, REMARK 3 : WOMACK,MATTHEWS,TEN EYCK,TRONRUD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.60 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 35.04 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 94.9 REMARK 3 NUMBER OF REFLECTIONS : 48205 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.177 REMARK 3 R VALUE (WORKING SET) : 0.176 REMARK 3 FREE R VALUE : 0.195 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.110 REMARK 3 FREE R VALUE TEST SET COUNT : 2462 REMARK 3 ESTIMATED ERROR OF FREE R VALUE : NULL REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (ANGSTROMS) : 1.60 REMARK 3 BIN RESOLUTION RANGE LOW (ANGSTROMS) : 1.64 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 94.90 REMARK 3 REFLECTIONS IN BIN (WORKING + TEST SET) : 3484 REMARK 3 BIN R VALUE (WORKING + TEST SET) : 0.2304 REMARK 3 REFLECTIONS IN BIN (WORKING SET) : 3337 REMARK 3 BIN R VALUE (WORKING SET) : 0.2296 REMARK 3 BIN FREE R VALUE : 0.2469 REMARK 3 BIN FREE R VALUE TEST SET SIZE (%) : 4.22 REMARK 3 BIN FREE R VALUE TEST SET COUNT : 147 REMARK 3 ESTIMATED ERROR OF BIN FREE R VALUE : NULL REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2460 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 265 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 22.19 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 29.98 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -4.98190 REMARK 3 B22 (A**2) : -0.69060 REMARK 3 B33 (A**2) : 5.67250 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : -0.90630 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED COORDINATE ERROR. REMARK 3 ESD FROM LUZZATI PLOT (A) : 0.18 REMARK 3 DPI (BLOW EQ-10) BASED ON R VALUE (A) : NULL REMARK 3 DPI (BLOW EQ-9) BASED ON FREE R VALUE (A) : NULL REMARK 3 DPI (CRUICKSHANK) BASED ON R VALUE (A) : 0.08 REMARK 3 DPI (CRUICKSHANK) BASED ON FREE R VALUE (A) : NULL REMARK 3 REMARK 3 REFERENCES: BLOW, D. (2002) ACTA CRYST D58, 792-797 REMARK 3 CRUICKSHANK, D.W.J. (1999) ACTA CRYST D55, 583-601 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.952 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.948 REMARK 3 REMARK 3 NUMBER OF GEOMETRIC FUNCTION TERMS DEFINED : 15 REMARK 3 TERM COUNT WEIGHT FUNCTION. REMARK 3 BOND LENGTHS : NULL ; NULL ; NULL REMARK 3 BOND ANGLES : NULL ; NULL ; NULL REMARK 3 TORSION ANGLES : NULL ; NULL ; NULL REMARK 3 TRIGONAL CARBON PLANES : NULL ; NULL ; NULL REMARK 3 GENERAL PLANES : NULL ; NULL ; NULL REMARK 3 ISOTROPIC THERMAL FACTORS : NULL ; NULL ; NULL REMARK 3 BAD NON-BONDED CONTACTS : NULL ; NULL ; NULL REMARK 3 IMPROPER TORSIONS : NULL ; NULL ; NULL REMARK 3 PSEUDOROTATION ANGLES : NULL ; NULL ; NULL REMARK 3 CHIRAL IMPROPER TORSION : NULL ; NULL ; NULL REMARK 3 SUM OF OCCUPANCIES : NULL ; NULL ; NULL REMARK 3 UTILITY DISTANCES : NULL ; NULL ; NULL REMARK 3 UTILITY ANGLES : NULL ; NULL ; NULL REMARK 3 UTILITY TORSION : NULL ; NULL ; NULL REMARK 3 IDEAL-DIST CONTACT TERM : NULL ; NULL ; NULL REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES. REMARK 3 BOND LENGTHS (A) : NULL REMARK 3 BOND ANGLES (DEGREES) : NULL REMARK 3 PEPTIDE OMEGA TORSION ANGLES (DEGREES) : 3.69 REMARK 3 OTHER TORSION ANGLES (DEGREES) : 19.45 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 3SRI COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 19-JUL-11. REMARK 100 THE RCSB ID CODE IS RCSB066562. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 28-FEB-11 REMARK 200 TEMPERATURE (KELVIN) : 110 REMARK 200 PH : 8.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : ESRF REMARK 200 BEAMLINE : ID29 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.95367 REMARK 200 MONOCHROMATOR : SI 111 CHANNEL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : PSI PILATUS 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS REMARK 200 DATA SCALING SOFTWARE : SCALA REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 48207 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.600 REMARK 200 RESOLUTION RANGE LOW (A) : 46.970 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 94.9 REMARK 200 DATA REDUNDANCY : 3.200 REMARK 200 R MERGE (I) : 0.05600 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 12.7000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.60 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.69 REMARK 200 COMPLETENESS FOR SHELL (%) : 92.8 REMARK 200 DATA REDUNDANCY IN SHELL : 3.20 REMARK 200 R MERGE FOR SHELL (I) : 0.61800 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 1.700 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: AMORE REMARK 200 STARTING MODEL: PDB ENTRY 1Z40 REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 40.36 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.06 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 20% PEG 4000, 0.1M TRIS/HCL, 0.1M REMARK 280 SODIUM ACETATE, 20% ISOPROPANOL, PH 8.6, VAPOR DIFFUSION, HANGING REMARK 280 DROP, TEMPERATURE 290K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 21 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 19.06850 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2370 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 13990 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -15.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLU A 95 REMARK 465 PHE A 96 REMARK 465 ILE A 97 REMARK 465 GLU A 98 REMARK 465 ILE A 99 REMARK 465 VAL A 100 REMARK 465 GLU A 101 REMARK 465 ARG A 102 REMARK 465 SER A 103 REMARK 465 ASN A 104 REMARK 465 TYR A 105 REMARK 465 MET A 106 REMARK 465 GLY A 107 REMARK 465 ARG A 261 REMARK 465 TYR A 262 REMARK 465 CYS A 263 REMARK 465 ASN A 264 REMARK 465 LYS A 265 REMARK 465 ASP A 266 REMARK 465 GLU A 267 REMARK 465 SER A 268 REMARK 465 LYS A 269 REMARK 465 ARG A 270 REMARK 465 ASN A 271 REMARK 465 SER A 272 REMARK 465 LYS A 351 REMARK 465 GLN A 352 REMARK 465 TYR A 353 REMARK 465 GLU A 354 REMARK 465 GLN A 355 REMARK 465 HIS A 356 REMARK 465 LEU A 357 REMARK 465 THR A 358 REMARK 465 ASP A 359 REMARK 465 TYR A 360 REMARK 465 GLU A 361 REMARK 465 LYS A 362 REMARK 465 ILE A 363 REMARK 465 LYS A 364 REMARK 465 GLU A 365 REMARK 465 GLY A 366 REMARK 465 PHE A 367 REMARK 465 LYS A 368 REMARK 465 ASN A 369 REMARK 465 LYS A 370 REMARK 465 ASN A 371 REMARK 465 ALA A 372 REMARK 465 ASP A 373 REMARK 465 MET A 374 REMARK 465 ILE A 375 REMARK 465 LYS A 376 REMARK 465 SER A 377 REMARK 465 ALA A 378 REMARK 465 PHE A 379 REMARK 465 LEU A 380 REMARK 465 PRO A 381 REMARK 465 THR A 382 REMARK 465 GLY A 383 REMARK 465 ALA A 384 REMARK 465 PHE A 385 REMARK 465 LYS A 386 REMARK 465 ALA A 387 REMARK 465 MET A 443 REMARK 465 VAL A 444 REMARK 465 PRO A 445 REMARK 465 ARG A 446 REMARK 465 ALA A 447 REMARK 465 ALA A 448 REMARK 465 ALA A 449 REMARK 465 ALA A 450 REMARK 465 ALA A 451 REMARK 465 SER A 452 REMARK 465 PHE A 453 REMARK 465 LEU A 454 REMARK 465 GLU A 455 REMARK 465 GLN A 456 REMARK 465 LYS A 457 REMARK 465 LEU A 458 REMARK 465 ILE A 459 REMARK 465 SER A 460 REMARK 465 GLU A 461 REMARK 465 GLU A 462 REMARK 465 ASP A 463 REMARK 465 LEU A 464 REMARK 465 ASN A 465 REMARK 465 SER A 466 REMARK 465 ALA A 467 REMARK 465 VAL A 468 REMARK 465 ASP A 469 REMARK 465 HIS A 470 REMARK 465 HIS A 471 REMARK 465 HIS A 472 REMARK 465 HIS A 473 REMARK 465 HIS A 474 REMARK 465 HIS A 475 REMARK 465 SER B 2052 REMARK 465 VAL B 2053 REMARK 465 VAL B 2054 REMARK 465 ASN B 2055 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 LYS A 177 CG CD CE NZ REMARK 470 ASP A 317 CG OD1 OD2 REMARK 470 ARG A 389 CD NE CZ NH1 NH2 REMARK 470 LYS A 405 CD CE NZ REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 LEU A 131 55.34 -142.90 REMARK 500 GLU A 159 50.62 39.19 REMARK 500 ASN A 160 -19.95 84.87 REMARK 500 ASN A 173 57.76 -93.11 REMARK 500 ASN A 257 89.32 -151.49 REMARK 500 PHE A 274 73.81 56.95 REMARK 500 ARG A 304 -62.63 -144.95 REMARK 500 ASP A 317 63.64 38.08 REMARK 500 ASN A 439 50.14 -114.85 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CHIRAL CENTERS REMARK 500 REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16) REMARK 500 REMARK 500 M RES CSSEQI IMPROPER EXPECTED FOUND DETAILS REMARK 500 PHE A 165 24.6 L L OUTSIDE RANGE REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 1Z40 RELATED DB: PDB REMARK 900 PLASMODIUM FALCIPARUM AMA1 REMARK 900 RELATED ID: 3SRJ RELATED DB: PDB REMARK 900 RELATED ID: 3ZWZ RELATED DB: PDB DBREF 3SRI A 97 442 UNP P50489 AMA1_PLAFC 97 442 DBREF 3SRI B 2027 2055 UNP Q8IKV6 Q8IKV6_PLAF7 2027 2055 SEQADV 3SRI GLU A 95 UNP P50489 EXPRESSION TAG SEQADV 3SRI PHE A 96 UNP P50489 EXPRESSION TAG SEQADV 3SRI LYS A 162 UNP P50489 ASN 162 ENGINEERED MUTATION SEQADV 3SRI VAL A 288 UNP P50489 THR 288 ENGINEERED MUTATION SEQADV 3SRI ASP A 373 UNP P50489 SER 373 ENGINEERED MUTATION SEQADV 3SRI ASP A 422 UNP P50489 ASN 422 ENGINEERED MUTATION SEQADV 3SRI LYS A 423 UNP P50489 SER 423 ENGINEERED MUTATION SEQADV 3SRI MET A 443 UNP P50489 EXPRESSION TAG SEQADV 3SRI VAL A 444 UNP P50489 EXPRESSION TAG SEQADV 3SRI PRO A 445 UNP P50489 EXPRESSION TAG SEQADV 3SRI ARG A 446 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 447 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 448 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 449 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 450 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 451 UNP P50489 EXPRESSION TAG SEQADV 3SRI SER A 452 UNP P50489 EXPRESSION TAG SEQADV 3SRI PHE A 453 UNP P50489 EXPRESSION TAG SEQADV 3SRI LEU A 454 UNP P50489 EXPRESSION TAG SEQADV 3SRI GLU A 455 UNP P50489 EXPRESSION TAG SEQADV 3SRI GLN A 456 UNP P50489 EXPRESSION TAG SEQADV 3SRI LYS A 457 UNP P50489 EXPRESSION TAG SEQADV 3SRI LEU A 458 UNP P50489 EXPRESSION TAG SEQADV 3SRI ILE A 459 UNP P50489 EXPRESSION TAG SEQADV 3SRI SER A 460 UNP P50489 EXPRESSION TAG SEQADV 3SRI GLU A 461 UNP P50489 EXPRESSION TAG SEQADV 3SRI GLU A 462 UNP P50489 EXPRESSION TAG SEQADV 3SRI ASP A 463 UNP P50489 EXPRESSION TAG SEQADV 3SRI LEU A 464 UNP P50489 EXPRESSION TAG SEQADV 3SRI ASN A 465 UNP P50489 EXPRESSION TAG SEQADV 3SRI SER A 466 UNP P50489 EXPRESSION TAG SEQADV 3SRI ALA A 467 UNP P50489 EXPRESSION TAG SEQADV 3SRI VAL A 468 UNP P50489 EXPRESSION TAG SEQADV 3SRI ASP A 469 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 470 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 471 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 472 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 473 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 474 UNP P50489 EXPRESSION TAG SEQADV 3SRI HIS A 475 UNP P50489 EXPRESSION TAG SEQRES 1 A 381 GLU PHE ILE GLU ILE VAL GLU ARG SER ASN TYR MET GLY SEQRES 2 A 381 ASN PRO TRP THR GLU TYR MET ALA LYS TYR ASP ILE GLU SEQRES 3 A 381 GLU VAL HIS GLY SER GLY ILE ARG VAL ASP LEU GLY GLU SEQRES 4 A 381 ASP ALA GLU VAL ALA GLY THR GLN TYR ARG LEU PRO SER SEQRES 5 A 381 GLY LYS CYS PRO VAL PHE GLY LYS GLY ILE ILE ILE GLU SEQRES 6 A 381 ASN SER LYS THR THR PHE LEU LYS PRO VAL ALA THR GLY SEQRES 7 A 381 ASN GLN ASP LEU LYS ASP GLY GLY PHE ALA PHE PRO PRO SEQRES 8 A 381 THR GLU PRO LEU ILE SER PRO MET THR LEU ASN GLY MET SEQRES 9 A 381 ARG ASP PHE TYR LYS ASN ASN GLU TYR VAL LYS ASN LEU SEQRES 10 A 381 ASP GLU LEU THR LEU CYS SER ARG HIS ALA GLY ASN MET SEQRES 11 A 381 ASN PRO ASP LYS ASP GLU ASN SER ASN TYR LYS TYR PRO SEQRES 12 A 381 ALA VAL TYR ASP ASP LYS ASP LYS LYS CYS HIS ILE LEU SEQRES 13 A 381 TYR ILE ALA ALA GLN GLU ASN ASN GLY PRO ARG TYR CYS SEQRES 14 A 381 ASN LYS ASP GLU SER LYS ARG ASN SER MET PHE CYS PHE SEQRES 15 A 381 ARG PRO ALA LYS ASP LYS SER PHE GLN ASN TYR VAL TYR SEQRES 16 A 381 LEU SER LYS ASN VAL VAL ASP ASN TRP GLU LYS VAL CYS SEQRES 17 A 381 PRO ARG LYS ASN LEU GLU ASN ALA LYS PHE GLY LEU TRP SEQRES 18 A 381 VAL ASP GLY ASN CYS GLU ASP ILE PRO HIS VAL ASN GLU SEQRES 19 A 381 PHE SER ALA ASN ASP LEU PHE GLU CYS ASN LYS LEU VAL SEQRES 20 A 381 PHE GLU LEU SER ALA SER ASP GLN PRO LYS GLN TYR GLU SEQRES 21 A 381 GLN HIS LEU THR ASP TYR GLU LYS ILE LYS GLU GLY PHE SEQRES 22 A 381 LYS ASN LYS ASN ALA ASP MET ILE LYS SER ALA PHE LEU SEQRES 23 A 381 PRO THR GLY ALA PHE LYS ALA ASP ARG TYR LYS SER HIS SEQRES 24 A 381 GLY LYS GLY TYR ASN TRP GLY ASN TYR ASN ARG LYS THR SEQRES 25 A 381 HIS LYS CYS GLU ILE PHE ASN VAL LYS PRO THR CYS LEU SEQRES 26 A 381 ILE ASN ASP LYS SER TYR ILE ALA THR THR ALA LEU SER SEQRES 27 A 381 HIS PRO ILE GLU VAL GLU ASN ASN PHE PRO MET VAL PRO SEQRES 28 A 381 ARG ALA ALA ALA ALA ALA SER PHE LEU GLU GLN LYS LEU SEQRES 29 A 381 ILE SER GLU GLU ASP LEU ASN SER ALA VAL ASP HIS HIS SEQRES 30 A 381 HIS HIS HIS HIS SEQRES 1 B 29 LYS ASP ILE GLY ALA GLY PRO VAL ALA SER CYS PHE THR SEQRES 2 B 29 THR ARG MET SER PRO PRO GLN GLN ILE CYS LEU ASN SER SEQRES 3 B 29 VAL VAL ASN FORMUL 3 HOH *265(H2 O) HELIX 1 1 TRP A 110 ALA A 115 1 6 HELIX 2 2 ASP A 118 HIS A 123 1 6 HELIX 3 3 ASP A 175 GLY A 179 5 5 HELIX 4 4 LEU A 195 TYR A 202 1 8 HELIX 5 5 ASP A 212 ASN A 223 1 12 HELIX 6 6 LYS A 282 GLN A 285 5 4 HELIX 7 7 ASN A 297 CYS A 302 1 6 HELIX 8 8 ASP A 333 SER A 345 1 13 SHEET 1 A 2 GLU A 133 VAL A 137 0 SHEET 2 A 2 THR A 140 LEU A 144 -1 O TYR A 142 N ALA A 135 SHEET 1 B 5 VAL A 151 PHE A 152 0 SHEET 2 B 5 TYR A 287 LEU A 290 -1 O TYR A 289 N VAL A 151 SHEET 3 B 5 ALA A 238 ASP A 241 -1 N ALA A 238 O LEU A 290 SHEET 4 B 5 LYS A 246 ILE A 249 -1 O HIS A 248 N VAL A 239 SHEET 5 B 5 MET A 193 THR A 194 -1 N MET A 193 O CYS A 247 SHEET 1 C 2 LYS A 154 ILE A 158 0 SHEET 2 C 2 PHE A 276 LYS A 280 -1 O ARG A 277 N ILE A 157 SHEET 1 D 4 THR A 186 GLU A 187 0 SHEET 2 D 4 GLN B2047 LEU B2050 -1 O CYS B2049 N GLU A 187 SHEET 3 D 4 CYS B2037 THR B2040 -1 N PHE B2038 O ILE B2048 SHEET 4 D 4 MET A 224 ASN A 225 -1 N ASN A 225 O THR B2039 SHEET 1 E 6 ASN A 319 ASP A 322 0 SHEET 2 E 6 ASN A 306 VAL A 316 -1 N LEU A 314 O GLU A 321 SHEET 3 E 6 CYS A 418 THR A 429 -1 O ILE A 420 N LYS A 311 SHEET 4 E 6 TRP A 399 ASN A 403 -1 N TYR A 402 O ILE A 426 SHEET 5 E 6 LYS A 408 PHE A 412 -1 O LYS A 408 N ASN A 403 SHEET 6 E 6 ASN A 327 SER A 330 -1 N PHE A 329 O CYS A 409 SHEET 1 F 3 ASN A 319 ASP A 322 0 SHEET 2 F 3 ASN A 306 VAL A 316 -1 N LEU A 314 O GLU A 321 SHEET 3 F 3 VAL A 437 GLU A 438 1 O GLU A 438 N GLU A 308 SSBOND 1 CYS A 149 CYS A 302 1555 1555 2.08 SSBOND 2 CYS A 217 CYS A 247 1555 1555 2.07 SSBOND 3 CYS A 320 CYS A 418 1555 1555 2.03 SSBOND 4 CYS A 337 CYS A 409 1555 1555 2.07 SSBOND 5 CYS B 2037 CYS B 2049 1555 1555 2.04 CISPEP 1 GLU A 187 PRO A 188 0 -0.76 CISPEP 2 SER A 191 PRO A 192 0 -6.42 CISPEP 3 SER B 2043 PRO B 2044 0 1.12 CRYST1 70.724 38.137 72.078 90.00 97.72 90.00 P 1 21 1 2 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.014139 0.000000 0.001917 0.00000 SCALE2 0.000000 0.026221 0.000000 0.00000 SCALE3 0.000000 0.000000 0.014001 0.00000 ATOM 1 N ASN A 108 44.706 17.317 29.926 1.00 37.47 N ATOM 2 CA ASN A 108 44.570 15.904 29.576 1.00 36.43 C ATOM 3 C ASN A 108 45.223 15.618 28.210 1.00 37.20 C ATOM 4 O ASN A 108 44.738 16.108 27.181 1.00 38.06 O ATOM 5 CB ASN A 108 43.077 15.453 29.596 1.00 37.06 C ATOM 6 CG ASN A 108 42.850 13.943 29.528 1.00 43.43 C ATOM 7 OD1 ASN A 108 43.778 13.142 29.402 1.00 36.22 O ATOM 8 ND2 ASN A 108 41.602 13.510 29.642 1.00 29.43 N ATOM 9 N PRO A 109 46.321 14.830 28.177 1.00 31.64 N ATOM 10 CA PRO A 109 46.952 14.500 26.886 1.00 30.77 C ATOM 11 C PRO A 109 46.131 13.499 26.048 1.00 31.24 C ATOM 12 O PRO A 109 46.417 13.316 24.867 1.00 29.73 O ATOM 13 CB PRO A 109 48.282 13.877 27.315 1.00 32.74 C ATOM 14 CG PRO A 109 47.951 13.193 28.615 1.00 36.87 C ATOM 15 CD PRO A 109 47.014 14.156 29.296 1.00 32.63 C ATOM 16 N TRP A 110 45.117 12.860 26.666 1.00 27.64 N ATOM 17 CA TRP A 110 44.252 11.859 26.027 1.00 25.91 C ATOM 18 C TRP A 110 43.047 12.445 25.264 1.00 28.46 C ATOM 19 O TRP A 110 42.383 11.685 24.561 1.00 25.75 O ATOM 20 CB TRP A 110 43.737 10.860 27.086 1.00 24.05 C ATOM 21 CG TRP A 110 44.793 9.920 27.579 1.00 23.79 C ATOM 22 CD1 TRP A 110 45.530 10.028 28.727 1.00 26.12 C ATOM 23 CD2 TRP A 110 45.217 8.717 26.939 1.00 23.26 C ATOM 24 NE1 TRP A 110 46.360 8.938 28.856 1.00 24.94 N ATOM 25 CE2 TRP A 110 46.237 8.150 27.742 1.00 26.29 C ATOM 26 CE3 TRP A 110 44.870 8.081 25.735 1.00 24.49 C ATOM 27 CZ2 TRP A 110 46.903 6.973 27.384 1.00 25.57 C ATOM 28 CZ3 TRP A 110 45.518 6.905 25.391 1.00 25.70 C ATOM 29 CH2 TRP A 110 46.529 6.366 26.206 1.00 26.54 C ATOM 30 N THR A 111 42.739 13.751 25.419 1.00 25.80 N ATOM 31 CA THR A 111 41.555 14.395 24.806 1.00 26.08 C ATOM 32 C THR A 111 41.242 13.988 23.355 1.00 30.25 C ATOM 33 O THR A 111 40.154 13.468 23.065 1.00 27.17 O ATOM 34 CB THR A 111 41.599 15.921 25.003 1.00 36.56 C ATOM 35 OG1 THR A 111 41.786 16.176 26.386 1.00 36.54 O ATOM 36 CG2 THR A 111 40.326 16.621 24.508 1.00 34.23 C ATOM 37 N GLU A 112 42.193 14.243 22.456 1.00 28.73 N ATOM 38 CA GLU A 112 42.063 13.941 21.028 1.00 28.80 C ATOM 39 C GLU A 112 41.827 12.453 20.791 1.00 28.50 C ATOM 40 O GLU A 112 40.863 12.100 20.116 1.00 27.87 O ATOM 41 CB GLU A 112 43.303 14.435 20.244 1.00 31.13 C ATOM 42 CG GLU A 112 43.569 15.937 20.344 1.00 47.47 C ATOM 43 CD GLU A 112 43.962 16.513 21.697 1.00 71.48 C ATOM 44 OE1 GLU A 112 44.508 15.768 22.548 1.00 59.52 O ATOM 45 OE2 GLU A 112 43.694 17.718 21.912 1.00 66.16 O ATOM 46 N TYR A 113 42.671 11.585 21.377 1.00 23.06 N ATOM 47 CA TYR A 113 42.560 10.139 21.208 1.00 22.22 C ATOM 48 C TYR A 113 41.210 9.623 21.706 1.00 22.06 C ATOM 49 O TYR A 113 40.632 8.732 21.084 1.00 21.27 O ATOM 50 CB TYR A 113 43.683 9.401 21.957 1.00 23.15 C ATOM 51 CG TYR A 113 43.734 7.926 21.629 1.00 25.45 C ATOM 52 CD1 TYR A 113 44.466 7.460 20.541 1.00 27.53 C ATOM 53 CD2 TYR A 113 43.033 6.994 22.394 1.00 25.89 C ATOM 54 CE1 TYR A 113 44.499 6.105 20.219 1.00 29.29 C ATOM 55 CE2 TYR A 113 43.019 5.643 22.052 1.00 26.46 C ATOM 56 CZ TYR A 113 43.781 5.198 20.984 1.00 32.19 C ATOM 57 OH TYR A 113 43.795 3.864 20.661 1.00 31.11 O ATOM 58 N MET A 114 40.753 10.160 22.846 1.00 19.20 N ATOM 59 CA MET A 114 39.525 9.683 23.498 1.00 17.24 C ATOM 60 C MET A 114 38.230 10.204 22.920 1.00 18.11 C ATOM 61 O MET A 114 37.156 9.738 23.315 1.00 16.91 O ATOM 62 CB MET A 114 39.581 9.883 25.026 1.00 18.09 C ATOM 63 CG MET A 114 40.689 9.075 25.699 1.00 20.33 C ATOM 64 SD MET A 114 40.598 7.276 25.431 1.00 20.61 S ATOM 65 CE MET A 114 39.067 6.882 26.336 1.00 18.62 C ATOM 66 N ALA A 115 38.305 11.155 21.967 1.00 17.94 N ATOM 67 CA ALA A 115 37.085 11.747 21.410 1.00 19.14 C ATOM 68 C ALA A 115 36.177 10.690 20.791 1.00 17.51 C ATOM 69 O ALA A 115 34.960 10.780 20.952 1.00 18.45 O ATOM 70 CB ALA A 115 37.452 12.802 20.366 1.00 19.96 C ATOM 71 N LYS A 116 36.754 9.659 20.141 1.00 15.34 N ATOM 72 CA LYS A 116 35.885 8.661 19.495 1.00 15.58 C ATOM 73 C LYS A 116 35.106 7.787 20.491 1.00 17.89 C ATOM 74 O LYS A 116 34.157 7.133 20.087 1.00 16.29 O ATOM 75 CB LYS A 116 36.648 7.803 18.500 1.00 18.45 C ATOM 76 CG LYS A 116 37.661 6.867 19.094 1.00 18.60 C ATOM 77 CD LYS A 116 38.179 5.868 18.020 1.00 22.97 C ATOM 78 CE LYS A 116 38.666 6.472 16.701 1.00 31.39 C ATOM 79 NZ LYS A 116 39.721 7.499 16.907 1.00 32.76 N ATOM 80 N TYR A 117 35.495 7.833 21.788 1.00 16.17 N ATOM 81 CA TYR A 117 34.789 7.057 22.815 1.00 15.52 C ATOM 82 C TYR A 117 33.702 7.867 23.538 1.00 18.76 C ATOM 83 O TYR A 117 32.970 7.322 24.370 1.00 18.41 O ATOM 84 CB TYR A 117 35.787 6.369 23.758 1.00 16.42 C ATOM 85 CG TYR A 117 36.705 5.461 22.967 1.00 17.68 C ATOM 86 CD1 TYR A 117 38.018 5.832 22.692 1.00 19.54 C ATOM 87 CD2 TYR A 117 36.228 4.284 22.395 1.00 19.25 C ATOM 88 CE1 TYR A 117 38.848 5.027 21.905 1.00 17.95 C ATOM 89 CE2 TYR A 117 37.032 3.499 21.576 1.00 19.69 C ATOM 90 CZ TYR A 117 38.339 3.880 21.320 1.00 25.35 C ATOM 91 OH TYR A 117 39.133 3.099 20.514 1.00 23.20 O ATOM 92 N ASP A 118 33.555 9.153 23.176 1.00 15.79 N ATOM 93 CA ASP A 118 32.480 9.981 23.729 1.00 15.94 C ATOM 94 C ASP A 118 31.283 9.726 22.858 1.00 17.73 C ATOM 95 O ASP A 118 30.981 10.516 21.948 1.00 15.26 O ATOM 96 CB ASP A 118 32.862 11.481 23.756 1.00 16.72 C ATOM 97 CG ASP A 118 31.841 12.396 24.433 1.00 21.66 C ATOM 98 OD1 ASP A 118 32.152 13.585 24.625 1.00 22.00 O ATOM 99 OD2 ASP A 118 30.743 11.907 24.810 1.00 21.99 O ATOM 100 N ILE A 119 30.614 8.586 23.114 1.00 16.58 N ATOM 101 CA ILE A 119 29.488 8.113 22.322 1.00 16.89 C ATOM 102 C ILE A 119 28.293 9.087 22.238 1.00 19.61 C ATOM 103 O ILE A 119 27.676 9.195 21.181 1.00 18.99 O ATOM 104 CB ILE A 119 29.158 6.642 22.726 1.00 20.42 C ATOM 105 CG1 ILE A 119 30.270 5.717 22.116 1.00 21.89 C ATOM 106 CG2 ILE A 119 27.760 6.252 22.233 1.00 20.43 C ATOM 107 CD1 ILE A 119 30.453 4.347 22.816 1.00 34.18 C ATOM 108 N GLU A 120 28.006 9.863 23.322 1.00 17.98 N ATOM 109 CA GLU A 120 26.945 10.854 23.286 1.00 18.82 C ATOM 110 C GLU A 120 27.249 11.892 22.214 1.00 22.32 C ATOM 111 O GLU A 120 26.343 12.348 21.531 1.00 22.91 O ATOM 112 CB GLU A 120 26.862 11.584 24.627 1.00 21.07 C ATOM 113 CG GLU A 120 25.768 11.066 25.505 1.00 29.13 C ATOM 114 CD GLU A 120 25.657 11.914 26.751 1.00 36.09 C ATOM 115 OE1 GLU A 120 24.994 12.975 26.701 1.00 25.37 O ATOM 116 OE2 GLU A 120 26.313 11.558 27.752 1.00 27.63 O ATOM 117 N GLU A 121 28.515 12.297 22.108 1.00 17.65 N ATOM 118 CA GLU A 121 28.941 13.299 21.138 1.00 18.36 C ATOM 119 C GLU A 121 29.041 12.733 19.721 1.00 21.99 C ATOM 120 O GLU A 121 28.482 13.316 18.789 1.00 23.56 O ATOM 121 CB GLU A 121 30.289 13.903 21.561 1.00 19.83 C ATOM 122 CG GLU A 121 30.767 15.049 20.672 1.00 29.67 C ATOM 123 CD GLU A 121 29.812 16.226 20.528 1.00 52.09 C ATOM 124 OE1 GLU A 121 29.135 16.581 21.521 1.00 44.83 O ATOM 125 OE2 GLU A 121 29.749 16.799 19.417 1.00 50.80 O ATOM 126 N VAL A 122 29.838 11.658 19.542 1.00 17.21 N ATOM 127 CA VAL A 122 30.147 11.119 18.217 1.00 16.37 C ATOM 128 C VAL A 122 29.011 10.341 17.556 1.00 19.34 C ATOM 129 O VAL A 122 28.946 10.299 16.326 1.00 19.67 O ATOM 130 CB VAL A 122 31.524 10.387 18.123 1.00 21.14 C ATOM 131 CG1 VAL A 122 32.674 11.329 18.498 1.00 21.77 C ATOM 132 CG2 VAL A 122 31.563 9.110 18.959 1.00 20.08 C ATOM 133 N HIS A 123 28.204 9.636 18.347 1.00 15.07 N ATOM 134 CA HIS A 123 27.102 8.815 17.829 1.00 13.93 C ATOM 135 C HIS A 123 25.789 9.541 18.036 1.00 18.30 C ATOM 136 O HIS A 123 25.041 9.721 17.085 1.00 17.00 O ATOM 137 CB HIS A 123 27.058 7.429 18.474 1.00 13.07 C ATOM 138 CG HIS A 123 26.042 6.516 17.871 1.00 14.88 C ATOM 139 ND1 HIS A 123 26.149 6.081 16.552 1.00 15.10 N ATOM 140 CD2 HIS A 123 24.998 5.883 18.455 1.00 16.04 C ATOM 141 CE1 HIS A 123 25.148 5.239 16.371 1.00 15.50 C ATOM 142 NE2 HIS A 123 24.427 5.085 17.493 1.00 15.98 N ATOM 143 N GLY A 124 25.525 9.949 19.274 1.00 16.70 N ATOM 144 CA GLY A 124 24.376 10.786 19.611 1.00 16.40 C ATOM 145 C GLY A 124 22.979 10.202 19.553 1.00 19.97 C ATOM 146 O GLY A 124 22.000 10.957 19.562 1.00 20.22 O ATOM 147 N SER A 125 22.857 8.857 19.527 1.00 16.30 N ATOM 148 CA SER A 125 21.547 8.218 19.475 1.00 14.64 C ATOM 149 C SER A 125 21.681 6.828 20.123 1.00 16.82 C ATOM 150 O SER A 125 22.767 6.470 20.598 1.00 16.14 O ATOM 151 CB SER A 125 21.114 8.076 18.011 1.00 17.00 C ATOM 152 OG SER A 125 19.737 7.751 17.979 1.00 19.04 O ATOM 153 N GLY A 126 20.604 6.064 20.141 1.00 14.38 N ATOM 154 CA GLY A 126 20.664 4.710 20.661 1.00 14.17 C ATOM 155 C GLY A 126 21.574 3.809 19.816 1.00 17.20 C ATOM 156 O GLY A 126 21.899 4.123 18.663 1.00 17.96 O ATOM 157 N ILE A 127 22.059 2.737 20.425 1.00 15.32 N ATOM 158 CA ILE A 127 22.951 1.775 19.775 1.00 13.60 C ATOM 159 C ILE A 127 22.162 0.478 19.620 1.00 16.69 C ATOM 160 O ILE A 127 21.916 0.045 18.490 1.00 16.80 O ATOM 161 CB ILE A 127 24.287 1.606 20.556 1.00 15.59 C ATOM 162 CG1 ILE A 127 25.036 2.983 20.628 1.00 15.70 C ATOM 163 CG2 ILE A 127 25.140 0.469 19.916 1.00 15.74 C ATOM 164 CD1 ILE A 127 26.303 2.989 21.563 1.00 18.55 C ATOM 165 N ARG A 128 21.721 -0.121 20.748 1.00 15.30 N ATOM 166 CA ARG A 128 20.891 -1.343 20.685 1.00 15.42 C ATOM 167 C ARG A 128 19.676 -1.115 19.808 1.00 16.61 C ATOM 168 O ARG A 128 19.435 -1.876 18.864 1.00 17.97 O ATOM 169 CB ARG A 128 20.473 -1.799 22.090 1.00 15.90 C ATOM 170 CG ARG A 128 19.859 -3.199 22.069 1.00 20.72 C ATOM 171 CD ARG A 128 19.350 -3.567 23.454 1.00 31.77 C ATOM 172 NE ARG A 128 18.744 -4.898 23.472 1.00 45.85 N ATOM 173 CZ ARG A 128 17.471 -5.141 23.185 1.00 55.68 C ATOM 174 NH1 ARG A 128 16.654 -4.147 22.872 1.00 38.67 N ATOM 175 NH2 ARG A 128 17.005 -6.382 23.206 1.00 48.48 N ATOM 176 N VAL A 129 18.938 -0.038 20.107 1.00 16.32 N ATOM 177 CA VAL A 129 17.795 0.405 19.309 1.00 16.66 C ATOM 178 C VAL A 129 18.053 1.869 19.040 1.00 19.13 C ATOM 179 O VAL A 129 18.098 2.675 19.986 1.00 17.65 O ATOM 180 CB VAL A 129 16.408 0.163 19.988 1.00 20.68 C ATOM 181 CG1 VAL A 129 15.288 0.853 19.204 1.00 20.71 C ATOM 182 CG2 VAL A 129 16.125 -1.331 20.154 1.00 20.57 C ATOM 183 N ASP A 130 18.210 2.221 17.759 1.00 15.12 N ATOM 184 CA ASP A 130 18.453 3.591 17.330 1.00 14.97 C ATOM 185 C ASP A 130 17.176 4.117 16.671 1.00 19.57 C ATOM 186 O ASP A 130 16.797 3.684 15.570 1.00 18.76 O ATOM 187 CB ASP A 130 19.656 3.631 16.332 1.00 15.48 C ATOM 188 CG ASP A 130 19.919 4.999 15.699 1.00 20.98 C ATOM 189 OD1 ASP A 130 19.219 5.983 16.064 1.00 18.59 O ATOM 190 OD2 ASP A 130 20.752 5.072 14.790 1.00 20.76 O ATOM 191 N LEU A 131 16.506 5.045 17.370 1.00 17.36 N ATOM 192 CA LEU A 131 15.300 5.717 16.856 1.00 17.43 C ATOM 193 C LEU A 131 15.403 7.161 17.354 1.00 22.00 C ATOM 194 O LEU A 131 14.515 7.667 18.045 1.00 23.80 O ATOM 195 CB LEU A 131 14.015 5.003 17.354 1.00 17.13 C ATOM 196 CG LEU A 131 13.714 3.617 16.769 1.00 21.54 C ATOM 197 CD1 LEU A 131 12.578 2.931 17.528 1.00 22.40 C ATOM 198 CD2 LEU A 131 13.454 3.668 15.230 1.00 21.64 C ATOM 199 N GLY A 132 16.520 7.802 17.027 1.00 18.24 N ATOM 200 CA GLY A 132 16.855 9.108 17.579 1.00 18.54 C ATOM 201 C GLY A 132 16.258 10.332 16.928 1.00 22.64 C ATOM 202 O GLY A 132 16.462 11.443 17.419 1.00 22.44 O ATOM 203 N GLU A 133 15.565 10.150 15.798 1.00 21.10 N ATOM 204 CA GLU A 133 14.934 11.289 15.139 1.00 20.42 C ATOM 205 C GLU A 133 13.509 10.929 14.744 1.00 23.80 C ATOM 206 O GLU A 133 13.072 9.780 14.857 1.00 22.75 O ATOM 207 CB GLU A 133 15.743 11.708 13.905 1.00 21.63 C ATOM 208 CG GLU A 133 16.941 12.596 14.202 1.00 26.55 C ATOM 209 CD GLU A 133 17.701 13.024 12.959 1.00 32.40 C ATOM 210 OE1 GLU A 133 18.888 13.402 13.076 1.00 26.57 O ATOM 211 OE2 GLU A 133 17.095 13.016 11.864 1.00 27.50 O ATOM 212 N ASP A 134 12.773 11.943 14.317 1.00 22.93 N ATOM 213 CA ASP A 134 11.424 11.780 13.799 1.00 23.29 C ATOM 214 C ASP A 134 11.396 12.427 12.422 1.00 28.11 C ATOM 215 O ASP A 134 12.097 13.415 12.179 1.00 29.77 O ATOM 216 CB ASP A 134 10.382 12.408 14.743 1.00 25.01 C ATOM 217 CG ASP A 134 10.517 11.908 16.180 1.00 31.82 C ATOM 218 OD1 ASP A 134 10.099 10.763 16.453 1.00 30.82 O ATOM 219 OD2 ASP A 134 11.079 12.650 17.021 1.00 39.13 O ATOM 220 N ALA A 135 10.661 11.834 11.507 1.00 26.68 N ATOM 221 CA ALA A 135 10.521 12.375 10.154 1.00 27.70 C ATOM 222 C ALA A 135 9.076 12.206 9.723 1.00 34.33 C ATOM 223 O ALA A 135 8.391 11.303 10.189 1.00 34.63 O ATOM 224 CB ALA A 135 11.452 11.661 9.185 1.00 28.23 C ATOM 225 N GLU A 136 8.622 13.065 8.834 1.00 33.95 N ATOM 226 CA GLU A 136 7.242 13.026 8.375 1.00 35.07 C ATOM 227 C GLU A 136 7.130 12.525 6.935 1.00 38.14 C ATOM 228 O GLU A 136 7.916 12.932 6.075 1.00 38.42 O ATOM 229 CB GLU A 136 6.631 14.425 8.516 1.00 36.99 C ATOM 230 CG GLU A 136 5.136 14.434 8.781 1.00 54.84 C ATOM 231 CD GLU A 136 4.570 15.804 9.106 1.00 82.30 C ATOM 232 OE1 GLU A 136 4.143 16.010 10.265 1.00 75.67 O ATOM 233 OE2 GLU A 136 4.564 16.677 8.207 1.00 79.82 O ATOM 234 N VAL A 137 6.194 11.597 6.696 1.00 33.50 N ATOM 235 CA VAL A 137 5.848 11.105 5.361 1.00 33.15 C ATOM 236 C VAL A 137 4.345 11.365 5.238 1.00 39.86 C ATOM 237 O VAL A 137 3.566 10.824 6.026 1.00 38.62 O ATOM 238 CB VAL A 137 6.192 9.615 5.079 1.00 36.07 C ATOM 239 CG1 VAL A 137 5.724 9.190 3.682 1.00 35.81 C ATOM 240 CG2 VAL A 137 7.686 9.360 5.224 1.00 35.25 C ATOM 241 N ALA A 138 3.962 12.221 4.275 1.00 39.36 N ATOM 242 CA ALA A 138 2.577 12.580 3.951 1.00 40.33 C ATOM 243 C ALA A 138 1.680 12.883 5.173 1.00 46.37 C ATOM 244 O ALA A 138 0.651 12.229 5.382 1.00 47.11 O ATOM 245 CB ALA A 138 1.968 11.508 3.067 1.00 41.09 C ATOM 246 N GLY A 139 2.128 13.837 5.990 1.00 43.41 N ATOM 247 CA GLY A 139 1.418 14.298 7.182 1.00 43.44 C ATOM 248 C GLY A 139 1.535 13.472 8.454 1.00 48.07 C ATOM 249 O GLY A 139 1.153 13.962 9.524 1.00 48.12 O ATOM 250 N THR A 140 2.036 12.210 8.360 1.00 43.52 N ATOM 251 CA THR A 140 2.207 11.302 9.507 1.00 42.72 C ATOM 252 C THR A 140 3.680 11.274 9.983 1.00 43.80 C ATOM 253 O THR A 140 4.583 11.156 9.155 1.00 42.02 O ATOM 254 CB THR A 140 1.652 9.915 9.156 1.00 54.24 C ATOM 255 OG1 THR A 140 0.302 10.070 8.715 1.00 58.48 O ATOM 256 CG2 THR A 140 1.699 8.933 10.331 1.00 52.52 C ATOM 257 N GLN A 141 3.905 11.381 11.310 1.00 38.78 N ATOM 258 CA GLN A 141 5.245 11.373 11.926 1.00 37.36 C ATOM 259 C GLN A 141 5.711 9.946 12.211 1.00 35.97 C ATOM 260 O GLN A 141 4.928 9.131 12.700 1.00 33.16 O ATOM 261 CB GLN A 141 5.250 12.182 13.232 1.00 39.12 C ATOM 262 CG GLN A 141 5.305 13.690 13.026 1.00 66.40 C ATOM 263 CD GLN A 141 6.718 14.221 13.048 1.00 93.65 C ATOM 264 OE1 GLN A 141 7.455 14.068 14.030 1.00 90.25 O ATOM 265 NE2 GLN A 141 7.110 14.901 11.980 1.00 88.71 N ATOM 266 N TYR A 142 6.987 9.641 11.894 1.00 29.88 N ATOM 267 CA TYR A 142 7.558 8.314 12.145 1.00 28.06 C ATOM 268 C TYR A 142 8.884 8.478 12.838 1.00 27.62 C ATOM 269 O TYR A 142 9.561 9.476 12.618 1.00 28.86 O ATOM 270 CB TYR A 142 7.796 7.545 10.831 1.00 29.56 C ATOM 271 CG TYR A 142 6.549 7.348 10.004 1.00 31.90 C ATOM 272 CD1 TYR A 142 6.189 8.265 9.019 1.00 33.72 C ATOM 273 CD2 TYR A 142 5.730 6.243 10.200 1.00 33.44 C ATOM 274 CE1 TYR A 142 5.030 8.092 8.260 1.00 34.93 C ATOM 275 CE2 TYR A 142 4.574 6.054 9.444 1.00 35.25 C ATOM 276 CZ TYR A 142 4.228 6.982 8.475 1.00 44.05 C ATOM 277 OH TYR A 142 3.086 6.796 7.738 1.00 49.01 O ATOM 278 N ARG A 143 9.265 7.487 13.631 1.00 23.02 N ATOM 279 CA ARG A 143 10.560 7.475 14.312 1.00 21.97 C ATOM 280 C ARG A 143 11.548 6.828 13.361 1.00 24.57 C ATOM 281 O ARG A 143 11.181 5.911 12.607 1.00 23.88 O ATOM 282 CB ARG A 143 10.488 6.626 15.588 1.00 22.50 C ATOM 283 CG ARG A 143 9.447 7.096 16.617 1.00 22.47 C ATOM 284 CD ARG A 143 9.663 6.366 17.935 1.00 26.42 C ATOM 285 NE ARG A 143 10.902 6.812 18.572 1.00 24.01 N ATOM 286 CZ ARG A 143 11.483 6.226 19.612 1.00 29.18 C ATOM 287 NH1 ARG A 143 10.962 5.123 20.140 1.00 23.63 N ATOM 288 NH2 ARG A 143 12.613 6.712 20.106 1.00 24.28 N ATOM 289 N LEU A 144 12.811 7.255 13.423 1.00 20.75 N ATOM 290 CA LEU A 144 13.784 6.601 12.551 1.00 20.98 C ATOM 291 C LEU A 144 15.213 6.654 13.066 1.00 20.82 C ATOM 292 O LEU A 144 15.526 7.529 13.860 1.00 20.02 O ATOM 293 CB LEU A 144 13.660 7.105 11.090 1.00 22.05 C ATOM 294 CG LEU A 144 14.318 8.395 10.670 1.00 26.65 C ATOM 295 CD1 LEU A 144 14.167 8.573 9.173 1.00 25.43 C ATOM 296 CD2 LEU A 144 13.736 9.614 11.412 1.00 31.94 C ATOM 297 N PRO A 145 16.072 5.685 12.669 1.00 18.50 N ATOM 298 CA PRO A 145 17.483 5.720 13.094 1.00 16.85 C ATOM 299 C PRO A 145 18.223 6.993 12.698 1.00 20.11 C ATOM 300 O PRO A 145 18.047 7.549 11.597 1.00 17.72 O ATOM 301 CB PRO A 145 18.084 4.464 12.430 1.00 18.52 C ATOM 302 CG PRO A 145 16.890 3.547 12.218 1.00 22.10 C ATOM 303 CD PRO A 145 15.835 4.534 11.773 1.00 19.02 C ATOM 304 N SER A 146 19.094 7.448 13.612 1.00 18.04 N ATOM 305 CA SER A 146 19.812 8.693 13.416 1.00 16.92 C ATOM 306 C SER A 146 21.256 8.717 13.963 1.00 17.99 C ATOM 307 O SER A 146 21.874 9.779 13.957 1.00 16.97 O ATOM 308 CB SER A 146 19.015 9.822 14.055 1.00 19.26 C ATOM 309 OG SER A 146 18.869 9.589 15.453 1.00 20.41 O ATOM 310 N GLY A 147 21.781 7.567 14.404 1.00 16.26 N ATOM 311 CA GLY A 147 23.142 7.505 14.957 1.00 16.09 C ATOM 312 C GLY A 147 24.204 7.893 13.941 1.00 18.60 C ATOM 313 O GLY A 147 24.121 7.484 12.777 1.00 17.64 O ATOM 314 N LYS A 148 25.212 8.692 14.368 1.00 13.47 N ATOM 315 CA LYS A 148 26.284 9.144 13.471 1.00 14.28 C ATOM 316 C LYS A 148 27.396 8.110 13.189 1.00 17.37 C ATOM 317 O LYS A 148 28.178 8.290 12.260 1.00 15.66 O ATOM 318 CB LYS A 148 26.843 10.491 13.909 1.00 16.65 C ATOM 319 CG LYS A 148 25.851 11.662 13.707 1.00 22.34 C ATOM 320 CD LYS A 148 26.395 12.973 14.314 1.00 23.40 C ATOM 321 CE LYS A 148 26.520 12.892 15.816 1.00 23.02 C ATOM 322 NZ LYS A 148 27.032 14.170 16.393 1.00 30.77 N ATOM 323 N CYS A 149 27.483 7.048 14.004 1.00 13.40 N ATOM 324 CA CYS A 149 28.502 6.010 13.801 1.00 14.85 C ATOM 325 C CYS A 149 27.906 4.727 13.246 1.00 14.48 C ATOM 326 O CYS A 149 26.804 4.335 13.630 1.00 14.97 O ATOM 327 CB CYS A 149 29.230 5.722 15.112 1.00 16.00 C ATOM 328 SG CYS A 149 30.272 7.099 15.686 1.00 19.79 S ATOM 329 N PRO A 150 28.727 3.936 12.526 1.00 13.87 N ATOM 330 CA PRO A 150 28.274 2.598 12.132 1.00 13.61 C ATOM 331 C PRO A 150 28.278 1.679 13.358 1.00 17.22 C ATOM 332 O PRO A 150 29.111 1.847 14.239 1.00 15.51 O ATOM 333 CB PRO A 150 29.330 2.130 11.137 1.00 15.00 C ATOM 334 CG PRO A 150 30.534 2.954 11.388 1.00 20.85 C ATOM 335 CD PRO A 150 30.093 4.231 12.045 1.00 15.62 C ATOM 336 N VAL A 151 27.353 0.722 13.409 1.00 12.11 N ATOM 337 CA VAL A 151 27.316 -0.218 14.549 1.00 11.33 C ATOM 338 C VAL A 151 27.803 -1.573 13.994 1.00 15.43 C ATOM 339 O VAL A 151 27.075 -2.216 13.213 1.00 15.66 O ATOM 340 CB VAL A 151 25.874 -0.329 15.109 1.00 15.05 C ATOM 341 CG1 VAL A 151 25.883 -1.238 16.341 1.00 14.01 C ATOM 342 CG2 VAL A 151 25.325 1.050 15.483 1.00 15.49 C ATOM 343 N PHE A 152 29.044 -1.978 14.359 1.00 11.67 N ATOM 344 CA PHE A 152 29.635 -3.185 13.783 1.00 9.65 C ATOM 345 C PHE A 152 29.100 -4.456 14.423 1.00 15.90 C ATOM 346 O PHE A 152 29.243 -4.650 15.622 1.00 14.69 O ATOM 347 CB PHE A 152 31.169 -3.189 13.941 1.00 11.59 C ATOM 348 CG PHE A 152 31.771 -2.106 13.074 1.00 11.55 C ATOM 349 CD1 PHE A 152 32.061 -0.854 13.606 1.00 12.49 C ATOM 350 CD2 PHE A 152 32.043 -2.344 11.728 1.00 14.36 C ATOM 351 CE1 PHE A 152 32.601 0.163 12.792 1.00 14.84 C ATOM 352 CE2 PHE A 152 32.554 -1.326 10.912 1.00 15.36 C ATOM 353 CZ PHE A 152 32.860 -0.099 11.457 1.00 14.81 C ATOM 354 N GLY A 153 28.556 -5.341 13.599 1.00 15.59 N ATOM 355 CA GLY A 153 28.104 -6.639 14.079 1.00 13.89 C ATOM 356 C GLY A 153 26.644 -6.715 14.459 1.00 16.83 C ATOM 357 O GLY A 153 26.212 -7.756 14.958 1.00 16.15 O ATOM 358 N LYS A 154 25.904 -5.603 14.335 1.00 13.45 N ATOM 359 CA LYS A 154 24.487 -5.587 14.682 1.00 12.90 C ATOM 360 C LYS A 154 23.612 -6.167 13.594 1.00 18.77 C ATOM 361 O LYS A 154 23.630 -5.697 12.441 1.00 18.26 O ATOM 362 CB LYS A 154 24.025 -4.179 15.061 1.00 12.77 C ATOM 363 CG LYS A 154 22.499 -3.968 15.110 1.00 14.68 C ATOM 364 CD LYS A 154 22.137 -2.571 15.614 1.00 14.90 C ATOM 365 CE LYS A 154 20.637 -2.372 15.502 1.00 17.09 C ATOM 366 NZ LYS A 154 20.214 -1.135 16.191 1.00 16.92 N ATOM 367 N GLY A 155 22.752 -7.090 14.023 1.00 16.60 N ATOM 368 CA GLY A 155 21.665 -7.593 13.201 1.00 16.77 C ATOM 369 C GLY A 155 20.358 -7.669 13.981 1.00 20.27 C ATOM 370 O GLY A 155 20.297 -7.301 15.160 1.00 20.38 O ATOM 371 N ILE A 156 19.281 -8.093 13.310 1.00 19.68 N ATOM 372 CA ILE A 156 17.959 -8.281 13.929 1.00 19.42 C ATOM 373 C ILE A 156 17.635 -9.790 13.852 1.00 24.27 C ATOM 374 O ILE A 156 17.655 -10.377 12.757 1.00 22.61 O ATOM 375 CB ILE A 156 16.834 -7.432 13.237 1.00 22.09 C ATOM 376 CG1 ILE A 156 17.146 -5.901 13.166 1.00 22.28 C ATOM 377 CG2 ILE A 156 15.469 -7.670 13.898 1.00 23.30 C ATOM 378 CD1 ILE A 156 17.523 -5.177 14.466 1.00 24.58 C ATOM 379 N ILE A 157 17.378 -10.410 15.017 1.00 22.06 N ATOM 380 CA ILE A 157 16.970 -11.817 15.090 1.00 22.99 C ATOM 381 C ILE A 157 15.442 -11.803 15.057 1.00 26.93 C ATOM 382 O ILE A 157 14.836 -11.077 15.842 1.00 24.44 O ATOM 383 CB ILE A 157 17.508 -12.520 16.368 1.00 27.03 C ATOM 384 CG1 ILE A 157 19.054 -12.639 16.341 1.00 27.61 C ATOM 385 CG2 ILE A 157 16.817 -13.901 16.571 1.00 28.80 C ATOM 386 CD1 ILE A 157 19.745 -13.226 17.685 1.00 30.60 C ATOM 387 N ILE A 158 14.832 -12.551 14.117 1.00 27.34 N ATOM 388 CA ILE A 158 13.370 -12.616 13.967 1.00 29.40 C ATOM 389 C ILE A 158 12.913 -14.007 14.415 1.00 40.61 C ATOM 390 O ILE A 158 13.277 -14.989 13.767 1.00 40.72 O ATOM 391 CB ILE A 158 12.909 -12.353 12.493 1.00 32.68 C ATOM 392 CG1 ILE A 158 13.323 -10.956 11.981 1.00 32.82 C ATOM 393 CG2 ILE A 158 11.369 -12.576 12.333 1.00 34.12 C ATOM 394 CD1 ILE A 158 13.225 -10.843 10.459 1.00 35.88 C ATOM 395 N GLU A 159 12.084 -14.085 15.476 1.00 42.21 N ATOM 396 CA GLU A 159 11.486 -15.339 15.993 1.00 44.59 C ATOM 397 C GLU A 159 12.467 -16.535 15.958 1.00 55.14 C ATOM 398 O GLU A 159 12.129 -17.584 15.393 1.00 55.99 O ATOM 399 CB GLU A 159 10.203 -15.694 15.195 1.00 45.99 C ATOM 400 CG GLU A 159 9.178 -14.581 15.055 1.00 57.23 C ATOM 401 CD GLU A 159 7.793 -14.926 15.563 1.00 83.16 C ATOM 402 OE1 GLU A 159 7.463 -14.527 16.703 1.00 78.86 O ATOM 403 OE2 GLU A 159 7.037 -15.596 14.823 1.00 81.76 O ATOM 404 N ASN A 160 13.701 -16.346 16.509 1.00 54.33 N ATOM 405 CA ASN A 160 14.813 -17.324 16.577 1.00 54.58 C ATOM 406 C ASN A 160 15.706 -17.374 15.313 1.00 57.50 C ATOM 407 O ASN A 160 16.845 -17.853 15.393 1.00 57.23 O ATOM 408 CB ASN A 160 14.340 -18.746 16.974 1.00 59.95 C ATOM 409 CG ASN A 160 13.869 -18.925 18.403 1.00 94.42 C ATOM 410 OD1 ASN A 160 14.356 -19.800 19.129 1.00 90.52 O ATOM 411 ND2 ASN A 160 12.862 -18.164 18.822 1.00 88.39 N ATOM 412 N SER A 161 15.199 -16.883 14.162 1.00 52.25 N ATOM 413 CA SER A 161 15.917 -16.896 12.879 1.00 51.38 C ATOM 414 C SER A 161 16.981 -15.798 12.731 1.00 53.93 C ATOM 415 O SER A 161 16.721 -14.625 13.012 1.00 51.28 O ATOM 416 CB SER A 161 14.943 -16.847 11.705 1.00 53.70 C ATOM 417 OG SER A 161 15.636 -16.986 10.475 1.00 60.82 O ATOM 418 N LYS A 162 18.160 -16.198 12.220 1.00 51.34 N ATOM 419 CA LYS A 162 19.319 -15.326 12.001 1.00 51.64 C ATOM 420 C LYS A 162 19.545 -14.974 10.520 1.00 57.06 C ATOM 421 O LYS A 162 20.127 -13.927 10.219 1.00 57.33 O ATOM 422 CB LYS A 162 20.580 -15.955 12.617 1.00 53.89 C ATOM 423 CG LYS A 162 20.538 -16.039 14.143 1.00 62.34 C ATOM 424 CD LYS A 162 21.530 -17.061 14.666 1.00 69.53 C ATOM 425 CE LYS A 162 21.084 -17.692 15.961 1.00 76.19 C ATOM 426 NZ LYS A 162 21.790 -18.978 16.215 1.00 84.27 N ATOM 427 N THR A 163 19.068 -15.833 9.598 1.00 53.15 N ATOM 428 CA THR A 163 19.229 -15.632 8.152 1.00 52.04 C ATOM 429 C THR A 163 17.978 -15.019 7.501 1.00 51.77 C ATOM 430 O THR A 163 17.853 -15.042 6.275 1.00 52.79 O ATOM 431 CB THR A 163 19.669 -16.954 7.477 1.00 64.32 C ATOM 432 OG1 THR A 163 18.761 -17.995 7.848 1.00 68.37 O ATOM 433 CG2 THR A 163 21.098 -17.357 7.840 1.00 62.66 C ATOM 434 N THR A 164 17.079 -14.433 8.304 1.00 42.99 N ATOM 435 CA THR A 164 15.830 -13.889 7.778 1.00 40.42 C ATOM 436 C THR A 164 15.765 -12.365 7.602 1.00 34.76 C ATOM 437 O THR A 164 15.109 -11.905 6.668 1.00 32.58 O ATOM 438 CB THR A 164 14.617 -14.523 8.528 1.00 55.08 C ATOM 439 OG1 THR A 164 14.589 -15.921 8.246 1.00 60.18 O ATOM 440 CG2 THR A 164 13.261 -13.918 8.150 1.00 54.04 C ATOM 441 N PHE A 165 16.366 -11.569 8.509 1.00 25.77 N ATOM 442 CA PHE A 165 16.146 -10.133 8.403 1.00 21.86 C ATOM 443 C PHE A 165 16.609 -9.418 7.138 1.00 22.73 C ATOM 444 O PHE A 165 16.012 -8.395 6.788 1.00 23.24 O ATOM 445 CB PHE A 165 16.501 -9.399 9.699 1.00 22.49 C ATOM 446 CG PHE A 165 17.834 -8.698 9.708 1.00 22.56 C ATOM 447 CD1 PHE A 165 17.904 -7.310 9.653 1.00 24.56 C ATOM 448 CD2 PHE A 165 19.015 -9.419 9.824 1.00 24.75 C ATOM 449 CE1 PHE A 165 19.150 -6.646 9.695 1.00 25.73 C ATOM 450 CE2 PHE A 165 20.256 -8.753 9.883 1.00 27.18 C ATOM 451 CZ PHE A 165 20.307 -7.373 9.816 1.00 24.10 C ATOM 452 N LEU A 166 17.642 -9.954 6.451 1.00 20.68 N ATOM 453 CA LEU A 166 18.090 -9.323 5.199 1.00 21.12 C ATOM 454 C LEU A 166 17.266 -9.794 3.991 1.00 26.34 C ATOM 455 O LEU A 166 17.446 -9.282 2.886 1.00 25.96 O ATOM 456 CB LEU A 166 19.603 -9.469 4.954 1.00 20.90 C ATOM 457 CG LEU A 166 20.551 -8.762 5.942 1.00 24.08 C ATOM 458 CD1 LEU A 166 22.000 -8.917 5.478 1.00 22.98 C ATOM 459 CD2 LEU A 166 20.218 -7.271 6.050 1.00 25.28 C ATOM 460 N LYS A 167 16.329 -10.746 4.203 1.00 24.98 N ATOM 461 CA LYS A 167 15.432 -11.152 3.111 1.00 25.18 C ATOM 462 C LYS A 167 14.490 -9.973 2.815 1.00 26.74 C ATOM 463 O LYS A 167 14.149 -9.217 3.736 1.00 26.13 O ATOM 464 CB LYS A 167 14.584 -12.390 3.491 1.00 27.71 C ATOM 465 CG LYS A 167 15.375 -13.679 3.670 1.00 37.99 C ATOM 466 CD LYS A 167 14.424 -14.836 4.000 1.00 53.54 C ATOM 467 CE LYS A 167 15.096 -16.019 4.673 1.00 69.71 C ATOM 468 NZ LYS A 167 16.126 -16.670 3.814 1.00 79.25 N ATOM 469 N PRO A 168 14.024 -9.800 1.559 1.00 25.60 N ATOM 470 CA PRO A 168 13.063 -8.720 1.284 1.00 25.67 C ATOM 471 C PRO A 168 11.798 -8.825 2.146 1.00 29.82 C ATOM 472 O PRO A 168 11.426 -9.924 2.603 1.00 29.76 O ATOM 473 CB PRO A 168 12.731 -8.912 -0.202 1.00 28.04 C ATOM 474 CG PRO A 168 13.903 -9.648 -0.761 1.00 32.59 C ATOM 475 CD PRO A 168 14.306 -10.588 0.339 1.00 27.91 C ATOM 476 N VAL A 169 11.170 -7.673 2.398 1.00 27.08 N ATOM 477 CA VAL A 169 9.917 -7.529 3.166 1.00 28.34 C ATOM 478 C VAL A 169 8.782 -8.221 2.364 1.00 35.14 C ATOM 479 O VAL A 169 8.910 -8.393 1.144 1.00 32.89 O ATOM 480 CB VAL A 169 9.623 -6.020 3.463 1.00 33.14 C ATOM 481 CG1 VAL A 169 9.284 -5.232 2.190 1.00 32.67 C ATOM 482 CG2 VAL A 169 8.540 -5.841 4.523 1.00 33.72 C ATOM 483 N ALA A 170 7.696 -8.619 3.058 1.00 36.98 N ATOM 484 CA ALA A 170 6.504 -9.246 2.473 1.00 38.29 C ATOM 485 C ALA A 170 5.898 -8.337 1.405 1.00 45.13 C ATOM 486 O ALA A 170 5.713 -7.143 1.653 1.00 44.98 O ATOM 487 CB ALA A 170 5.482 -9.518 3.566 1.00 39.06 C ATOM 488 N THR A 171 5.625 -8.895 0.214 1.00 44.86 N ATOM 489 CA THR A 171 5.072 -8.139 -0.916 1.00 46.66 C ATOM 490 C THR A 171 3.589 -8.403 -1.190 1.00 54.72 C ATOM 491 O THR A 171 3.200 -9.543 -1.458 1.00 54.27 O ATOM 492 CB THR A 171 5.927 -8.308 -2.181 1.00 55.51 C ATOM 493 OG1 THR A 171 6.133 -9.697 -2.443 1.00 55.53 O ATOM 494 CG2 THR A 171 7.259 -7.608 -2.072 1.00 56.02 C ATOM 495 N GLY A 172 2.801 -7.327 -1.146 1.00 54.12 N ATOM 496 CA GLY A 172 1.366 -7.319 -1.416 1.00 55.19 C ATOM 497 C GLY A 172 0.532 -8.209 -0.522 1.00 61.09 C ATOM 498 O GLY A 172 0.309 -7.887 0.649 1.00 61.22 O ATOM 499 N ASN A 173 0.069 -9.343 -1.078 1.00 59.27 N ATOM 500 CA ASN A 173 -0.767 -10.309 -0.364 1.00 59.88 C ATOM 501 C ASN A 173 0.069 -11.411 0.280 1.00 65.72 C ATOM 502 O ASN A 173 -0.108 -12.603 0.011 1.00 65.88 O ATOM 503 CB ASN A 173 -1.894 -10.853 -1.259 1.00 58.11 C ATOM 504 CG ASN A 173 -3.264 -10.760 -0.630 1.00 63.76 C ATOM 505 OD1 ASN A 173 -4.038 -11.723 -0.643 1.00 57.92 O ATOM 506 ND2 ASN A 173 -3.596 -9.604 -0.064 1.00 46.18 N ATOM 507 N GLN A 174 0.995 -10.972 1.140 1.00 62.76 N ATOM 508 CA GLN A 174 1.929 -11.787 1.904 1.00 62.28 C ATOM 509 C GLN A 174 1.885 -11.306 3.352 1.00 65.87 C ATOM 510 O GLN A 174 1.717 -10.109 3.606 1.00 65.03 O ATOM 511 CB GLN A 174 3.345 -11.595 1.350 1.00 63.63 C ATOM 512 CG GLN A 174 3.930 -12.798 0.630 1.00 79.10 C ATOM 513 CD GLN A 174 5.279 -12.451 0.042 1.00 98.19 C ATOM 514 OE1 GLN A 174 6.291 -12.352 0.745 1.00 93.16 O ATOM 515 NE2 GLN A 174 5.317 -12.227 -1.262 1.00 91.13 N ATOM 516 N ASP A 175 2.027 -12.234 4.297 1.00 62.87 N ATOM 517 CA ASP A 175 2.049 -11.921 5.726 1.00 62.97 C ATOM 518 C ASP A 175 3.460 -11.450 6.105 1.00 65.16 C ATOM 519 O ASP A 175 4.429 -11.973 5.555 1.00 63.68 O ATOM 520 CB ASP A 175 1.638 -13.156 6.557 1.00 65.41 C ATOM 521 CG ASP A 175 2.401 -14.433 6.226 1.00 79.55 C ATOM 522 OD1 ASP A 175 3.103 -14.954 7.123 1.00 80.69 O ATOM 523 OD2 ASP A 175 2.287 -14.916 5.072 1.00 85.86 O ATOM 524 N LEU A 176 3.574 -10.473 7.036 1.00 61.33 N ATOM 525 CA LEU A 176 4.854 -9.916 7.505 1.00 60.95 C ATOM 526 C LEU A 176 5.880 -10.972 7.919 1.00 62.98 C ATOM 527 O LEU A 176 7.051 -10.851 7.561 1.00 62.49 O ATOM 528 CB LEU A 176 4.656 -8.892 8.637 1.00 61.23 C ATOM 529 CG LEU A 176 4.395 -7.434 8.228 1.00 66.30 C ATOM 530 CD1 LEU A 176 4.178 -6.570 9.454 1.00 66.76 C ATOM 531 CD2 LEU A 176 5.550 -6.852 7.407 1.00 68.46 C ATOM 532 N LYS A 177 5.428 -12.028 8.623 1.00 58.09 N ATOM 533 CA LYS A 177 6.261 -13.144 9.078 1.00 56.92 C ATOM 534 C LYS A 177 6.790 -14.018 7.926 1.00 59.02 C ATOM 535 O LYS A 177 7.678 -14.844 8.151 1.00 58.82 O ATOM 536 CB LYS A 177 5.501 -13.990 10.115 1.00 59.92 C ATOM 537 N ASP A 178 6.267 -13.826 6.693 1.00 54.37 N ATOM 538 CA ASP A 178 6.708 -14.573 5.508 1.00 53.88 C ATOM 539 C ASP A 178 7.938 -13.931 4.835 1.00 53.25 C ATOM 540 O ASP A 178 8.507 -14.517 3.907 1.00 53.32 O ATOM 541 CB ASP A 178 5.554 -14.725 4.495 1.00 56.57 C ATOM 542 CG ASP A 178 5.655 -15.962 3.622 1.00 75.43 C ATOM 543 OD1 ASP A 178 5.909 -15.809 2.403 1.00 77.39 O ATOM 544 OD2 ASP A 178 5.474 -17.084 4.155 1.00 82.65 O ATOM 545 N GLY A 179 8.327 -12.743 5.303 1.00 45.57 N ATOM 546 CA GLY A 179 9.468 -12.007 4.765 1.00 43.37 C ATOM 547 C GLY A 179 10.424 -11.470 5.816 1.00 41.63 C ATOM 548 O GLY A 179 10.288 -11.764 7.008 1.00 39.54 O ATOM 549 N GLY A 180 11.393 -10.680 5.361 1.00 33.94 N ATOM 550 CA GLY A 180 12.385 -10.057 6.230 1.00 31.60 C ATOM 551 C GLY A 180 12.141 -8.573 6.391 1.00 30.51 C ATOM 552 O GLY A 180 10.991 -8.131 6.378 1.00 28.71 O ATOM 553 N PHE A 181 13.232 -7.785 6.498 1.00 23.74 N ATOM 554 CA PHE A 181 13.154 -6.344 6.726 1.00 21.41 C ATOM 555 C PHE A 181 13.634 -5.508 5.540 1.00 21.97 C ATOM 556 O PHE A 181 13.461 -4.285 5.552 1.00 20.35 O ATOM 557 CB PHE A 181 14.032 -5.981 7.956 1.00 23.00 C ATOM 558 CG PHE A 181 13.430 -6.190 9.324 1.00 25.91 C ATOM 559 CD1 PHE A 181 12.618 -7.288 9.588 1.00 31.24 C ATOM 560 CD2 PHE A 181 13.701 -5.308 10.360 1.00 28.16 C ATOM 561 CE1 PHE A 181 12.057 -7.472 10.857 1.00 32.71 C ATOM 562 CE2 PHE A 181 13.162 -5.513 11.630 1.00 31.27 C ATOM 563 CZ PHE A 181 12.339 -6.587 11.864 1.00 30.26 C ATOM 564 N ALA A 182 14.282 -6.149 4.557 1.00 21.26 N ATOM 565 CA ALA A 182 14.941 -5.436 3.466 1.00 20.32 C ATOM 566 C ALA A 182 13.999 -4.969 2.360 1.00 24.50 C ATOM 567 O ALA A 182 12.868 -5.448 2.252 1.00 24.06 O ATOM 568 CB ALA A 182 16.046 -6.305 2.883 1.00 20.26 C ATOM 569 N PHE A 183 14.484 -4.038 1.531 1.00 20.29 N ATOM 570 CA PHE A 183 13.716 -3.542 0.389 1.00 19.58 C ATOM 571 C PHE A 183 13.372 -4.700 -0.542 1.00 26.81 C ATOM 572 O PHE A 183 14.222 -5.560 -0.816 1.00 23.85 O ATOM 573 CB PHE A 183 14.539 -2.492 -0.386 1.00 20.01 C ATOM 574 CG PHE A 183 14.104 -1.065 -0.221 1.00 21.11 C ATOM 575 CD1 PHE A 183 13.907 -0.521 1.045 1.00 21.32 C ATOM 576 CD2 PHE A 183 14.011 -0.218 -1.324 1.00 25.39 C ATOM 577 CE1 PHE A 183 13.557 0.822 1.201 1.00 23.84 C ATOM 578 CE2 PHE A 183 13.666 1.130 -1.165 1.00 28.49 C ATOM 579 CZ PHE A 183 13.409 1.632 0.097 1.00 25.59 C ATOM 580 N PRO A 184 12.106 -4.781 -0.992 1.00 27.88 N ATOM 581 CA PRO A 184 11.758 -5.832 -1.956 1.00 28.52 C ATOM 582 C PRO A 184 12.303 -5.468 -3.354 1.00 31.70 C ATOM 583 O PRO A 184 12.750 -4.322 -3.543 1.00 29.18 O ATOM 584 CB PRO A 184 10.225 -5.861 -1.891 1.00 30.64 C ATOM 585 CG PRO A 184 9.836 -4.475 -1.538 1.00 34.72 C ATOM 586 CD PRO A 184 10.985 -3.837 -0.784 1.00 30.35 C ATOM 587 N PRO A 185 12.294 -6.408 -4.342 1.00 30.16 N ATOM 588 CA PRO A 185 12.841 -6.084 -5.673 1.00 30.49 C ATOM 589 C PRO A 185 12.234 -4.844 -6.322 1.00 33.67 C ATOM 590 O PRO A 185 11.026 -4.609 -6.232 1.00 32.67 O ATOM 591 CB PRO A 185 12.594 -7.360 -6.488 1.00 32.38 C ATOM 592 CG PRO A 185 12.470 -8.446 -5.486 1.00 35.85 C ATOM 593 CD PRO A 185 11.836 -7.815 -4.278 1.00 31.55 C ATOM 594 N THR A 186 13.103 -4.012 -6.907 1.00 30.21 N ATOM 595 CA THR A 186 12.734 -2.745 -7.545 1.00 30.49 C ATOM 596 C THR A 186 13.222 -2.719 -8.979 1.00 35.27 C ATOM 597 O THR A 186 14.062 -3.542 -9.365 1.00 33.60 O ATOM 598 CB THR A 186 13.395 -1.553 -6.803 1.00 39.23 C ATOM 599 OG1 THR A 186 14.800 -1.797 -6.639 1.00 37.57 O ATOM 600 CG2 THR A 186 12.752 -1.263 -5.462 1.00 40.93 C ATOM 601 N GLU A 187 12.686 -1.756 -9.756 1.00 35.68 N ATOM 602 CA AGLU A 187 13.065 -1.529 -11.147 0.50 35.87 C ATOM 603 CA BGLU A 187 13.093 -1.524 -11.138 0.50 35.89 C ATOM 604 C GLU A 187 13.373 -0.030 -11.337 1.00 39.28 C ATOM 605 O GLU A 187 12.451 0.787 -11.248 1.00 39.99 O ATOM 606 CB AGLU A 187 11.972 -2.025 -12.112 0.50 37.53 C ATOM 607 CB BGLU A 187 12.089 -2.093 -12.164 0.50 37.59 C ATOM 608 CG AGLU A 187 12.520 -2.842 -13.269 0.50 48.70 C ATOM 609 CG BGLU A 187 12.563 -2.021 -13.615 0.50 49.13 C ATOM 610 CD AGLU A 187 12.173 -4.317 -13.228 0.50 70.51 C ATOM 611 CD BGLU A 187 13.941 -2.580 -13.932 0.50 71.75 C ATOM 612 OE1AGLU A 187 11.051 -4.677 -13.651 0.50 62.60 O ATOM 613 OE1BGLU A 187 14.727 -1.866 -14.595 0.50 65.43 O ATOM 614 OE2AGLU A 187 13.031 -5.116 -12.787 0.50 64.49 O ATOM 615 OE2BGLU A 187 14.237 -3.724 -13.518 0.50 68.97 O ATOM 616 N PRO A 188 14.655 0.384 -11.542 1.00 34.54 N ATOM 617 CA PRO A 188 15.913 -0.411 -11.607 1.00 34.60 C ATOM 618 C PRO A 188 16.231 -1.020 -10.226 1.00 35.56 C ATOM 619 O PRO A 188 15.787 -0.457 -9.214 1.00 34.73 O ATOM 620 CB PRO A 188 16.961 0.623 -12.036 1.00 36.54 C ATOM 621 CG PRO A 188 16.422 1.941 -11.555 1.00 41.36 C ATOM 622 CD PRO A 188 14.924 1.828 -11.702 1.00 36.96 C ATOM 623 N LEU A 189 16.889 -2.201 -10.187 1.00 30.29 N ATOM 624 CA LEU A 189 17.210 -2.898 -8.925 1.00 29.67 C ATOM 625 C LEU A 189 18.211 -2.131 -8.060 1.00 31.99 C ATOM 626 O LEU A 189 19.407 -2.114 -8.355 1.00 31.69 O ATOM 627 CB LEU A 189 17.658 -4.358 -9.143 1.00 29.77 C ATOM 628 CG LEU A 189 17.906 -5.199 -7.861 1.00 34.78 C ATOM 629 CD1 LEU A 189 16.591 -5.508 -7.106 1.00 34.46 C ATOM 630 CD2 LEU A 189 18.636 -6.501 -8.192 1.00 38.63 C ATOM 631 N ILE A 190 17.713 -1.503 -6.983 1.00 26.23 N ATOM 632 CA ILE A 190 18.591 -0.705 -6.130 1.00 25.22 C ATOM 633 C ILE A 190 18.940 -1.315 -4.774 1.00 25.07 C ATOM 634 O ILE A 190 19.707 -0.714 -4.010 1.00 24.51 O ATOM 635 CB ILE A 190 18.181 0.792 -6.076 1.00 29.01 C ATOM 636 CG1 ILE A 190 16.689 0.964 -5.789 1.00 30.04 C ATOM 637 CG2 ILE A 190 18.558 1.486 -7.397 1.00 30.26 C ATOM 638 CD1 ILE A 190 16.174 0.539 -4.390 1.00 32.97 C ATOM 639 N SER A 191 18.347 -2.483 -4.449 1.00 19.61 N ATOM 640 CA SER A 191 18.644 -3.206 -3.207 1.00 19.31 C ATOM 641 C SER A 191 18.343 -4.692 -3.349 1.00 24.66 C ATOM 642 O SER A 191 17.235 -5.042 -3.757 1.00 25.76 O ATOM 643 CB SER A 191 17.941 -2.610 -1.985 1.00 20.75 C ATOM 644 OG SER A 191 18.343 -3.250 -0.780 1.00 18.31 O ATOM 645 N PRO A 192 19.276 -5.577 -2.935 1.00 22.08 N ATOM 646 CA PRO A 192 20.642 -5.247 -2.468 1.00 21.60 C ATOM 647 C PRO A 192 21.463 -4.730 -3.653 1.00 24.71 C ATOM 648 O PRO A 192 21.077 -4.922 -4.820 1.00 25.07 O ATOM 649 CB PRO A 192 21.164 -6.583 -1.922 1.00 23.82 C ATOM 650 CG PRO A 192 20.399 -7.645 -2.665 1.00 28.81 C ATOM 651 CD PRO A 192 19.058 -7.041 -3.019 1.00 24.04 C ATOM 652 N MET A 193 22.543 -4.018 -3.362 1.00 18.42 N ATOM 653 CA MET A 193 23.431 -3.497 -4.397 1.00 17.72 C ATOM 654 C MET A 193 24.864 -3.657 -3.950 1.00 20.75 C ATOM 655 O MET A 193 25.215 -3.228 -2.844 1.00 20.98 O ATOM 656 CB MET A 193 23.126 -2.035 -4.721 1.00 20.08 C ATOM 657 CG MET A 193 23.732 -1.581 -6.044 1.00 24.93 C ATOM 658 SD MET A 193 23.161 0.070 -6.519 1.00 29.71 S ATOM 659 CE MET A 193 22.802 -0.188 -8.247 1.00 28.15 C ATOM 660 N THR A 194 25.706 -4.241 -4.806 1.00 16.66 N ATOM 661 CA THR A 194 27.113 -4.365 -4.433 1.00 16.46 C ATOM 662 C THR A 194 27.789 -2.980 -4.385 1.00 18.74 C ATOM 663 O THR A 194 27.264 -1.993 -4.942 1.00 18.17 O ATOM 664 CB THR A 194 27.859 -5.233 -5.446 1.00 20.99 C ATOM 665 OG1 THR A 194 27.886 -4.525 -6.680 1.00 21.12 O ATOM 666 CG2 THR A 194 27.259 -6.630 -5.593 1.00 22.78 C ATOM 667 N LEU A 195 28.970 -2.921 -3.734 1.00 16.08 N ATOM 668 CA LEU A 195 29.740 -1.685 -3.659 1.00 15.43 C ATOM 669 C LEU A 195 30.036 -1.185 -5.073 1.00 16.80 C ATOM 670 O LEU A 195 29.810 -0.018 -5.364 1.00 14.82 O ATOM 671 CB LEU A 195 31.048 -1.900 -2.899 1.00 15.78 C ATOM 672 CG LEU A 195 31.970 -0.704 -2.842 1.00 18.78 C ATOM 673 CD1 LEU A 195 31.263 0.528 -2.205 1.00 18.04 C ATOM 674 CD2 LEU A 195 33.283 -1.066 -2.106 1.00 19.67 C ATOM 675 N ASN A 196 30.526 -2.087 -5.958 1.00 16.34 N ATOM 676 CA ASN A 196 30.821 -1.680 -7.315 1.00 16.03 C ATOM 677 C ASN A 196 29.587 -1.214 -8.068 1.00 18.52 C ATOM 678 O ASN A 196 29.686 -0.276 -8.848 1.00 18.65 O ATOM 679 CB ASN A 196 31.583 -2.780 -8.038 1.00 18.53 C ATOM 680 CG ASN A 196 33.032 -2.861 -7.570 1.00 29.23 C ATOM 681 OD1 ASN A 196 33.546 -1.983 -6.867 1.00 25.71 O ATOM 682 ND2 ASN A 196 33.713 -3.931 -7.909 1.00 23.59 N ATOM 683 N GLY A 197 28.445 -1.833 -7.771 1.00 15.76 N ATOM 684 CA GLY A 197 27.137 -1.462 -8.323 1.00 16.46 C ATOM 685 C GLY A 197 26.743 -0.048 -7.925 1.00 19.18 C ATOM 686 O GLY A 197 26.330 0.763 -8.780 1.00 18.41 O ATOM 687 N MET A 198 26.930 0.289 -6.636 1.00 15.05 N ATOM 688 CA MET A 198 26.635 1.648 -6.162 1.00 14.47 C ATOM 689 C MET A 198 27.583 2.674 -6.764 1.00 18.30 C ATOM 690 O MET A 198 27.141 3.749 -7.141 1.00 17.38 O ATOM 691 CB MET A 198 26.722 1.727 -4.623 1.00 15.68 C ATOM 692 CG MET A 198 25.721 0.854 -3.918 1.00 17.08 C ATOM 693 SD MET A 198 25.605 1.248 -2.135 1.00 18.70 S ATOM 694 CE MET A 198 27.256 0.663 -1.529 1.00 15.86 C ATOM 695 N ARG A 199 28.889 2.357 -6.821 1.00 15.56 N ATOM 696 CA ARG A 199 29.850 3.286 -7.416 1.00 15.78 C ATOM 697 C ARG A 199 29.485 3.555 -8.874 1.00 18.39 C ATOM 698 O ARG A 199 29.627 4.690 -9.322 1.00 18.81 O ATOM 699 CB ARG A 199 31.279 2.770 -7.310 1.00 16.70 C ATOM 700 CG ARG A 199 31.747 2.786 -5.868 1.00 16.76 C ATOM 701 CD ARG A 199 33.254 2.785 -5.729 1.00 20.65 C ATOM 702 NE ARG A 199 33.693 2.483 -4.365 1.00 22.30 N ATOM 703 CZ ARG A 199 33.610 3.309 -3.315 1.00 29.39 C ATOM 704 NH1 ARG A 199 33.064 4.519 -3.448 1.00 17.93 N ATOM 705 NH2 ARG A 199 34.030 2.912 -2.114 1.00 21.54 N ATOM 706 N ASP A 200 28.993 2.527 -9.594 1.00 16.19 N ATOM 707 CA ASP A 200 28.586 2.724 -11.006 1.00 16.88 C ATOM 708 C ASP A 200 27.296 3.557 -11.086 1.00 19.93 C ATOM 709 O ASP A 200 27.182 4.464 -11.926 1.00 18.14 O ATOM 710 CB ASP A 200 28.389 1.369 -11.692 1.00 18.47 C ATOM 711 CG ASP A 200 27.950 1.486 -13.144 1.00 32.23 C ATOM 712 OD1 ASP A 200 28.755 1.990 -13.974 1.00 31.02 O ATOM 713 OD2 ASP A 200 26.774 1.182 -13.429 1.00 37.02 O ATOM 714 N PHE A 201 26.322 3.252 -10.210 1.00 17.56 N ATOM 715 CA PHE A 201 25.014 3.942 -10.176 1.00 17.83 C ATOM 716 C PHE A 201 25.227 5.463 -9.968 1.00 21.81 C ATOM 717 O PHE A 201 24.494 6.271 -10.543 1.00 22.30 O ATOM 718 CB PHE A 201 24.143 3.360 -9.043 1.00 19.25 C ATOM 719 CG PHE A 201 22.725 3.873 -8.991 1.00 21.07 C ATOM 720 CD1 PHE A 201 21.732 3.310 -9.790 1.00 25.70 C ATOM 721 CD2 PHE A 201 22.373 4.904 -8.133 1.00 23.86 C ATOM 722 CE1 PHE A 201 20.420 3.822 -9.776 1.00 27.11 C ATOM 723 CE2 PHE A 201 21.053 5.390 -8.089 1.00 27.21 C ATOM 724 CZ PHE A 201 20.085 4.843 -8.907 1.00 26.35 C ATOM 725 N TYR A 202 26.243 5.837 -9.152 1.00 16.42 N ATOM 726 CA TYR A 202 26.554 7.234 -8.830 1.00 17.01 C ATOM 727 C TYR A 202 27.796 7.785 -9.548 1.00 20.50 C ATOM 728 O TYR A 202 28.319 8.820 -9.116 1.00 18.84 O ATOM 729 CB TYR A 202 26.709 7.385 -7.301 1.00 18.92 C ATOM 730 CG TYR A 202 25.432 7.069 -6.559 1.00 18.80 C ATOM 731 CD1 TYR A 202 24.316 7.894 -6.668 1.00 20.39 C ATOM 732 CD2 TYR A 202 25.339 5.947 -5.736 1.00 18.36 C ATOM 733 CE1 TYR A 202 23.118 7.584 -6.016 1.00 21.06 C ATOM 734 CE2 TYR A 202 24.160 5.647 -5.050 1.00 18.56 C ATOM 735 CZ TYR A 202 23.047 6.459 -5.206 1.00 21.42 C ATOM 736 OH TYR A 202 21.866 6.135 -4.585 1.00 18.34 O ATOM 737 N LYS A 203 28.215 7.142 -10.681 1.00 18.14 N ATOM 738 CA LYS A 203 29.451 7.542 -11.386 1.00 17.17 C ATOM 739 C LYS A 203 29.488 9.001 -11.835 1.00 20.00 C ATOM 740 O LYS A 203 30.582 9.546 -11.962 1.00 20.28 O ATOM 741 CB LYS A 203 29.772 6.603 -12.543 1.00 18.86 C ATOM 742 CG LYS A 203 28.793 6.703 -13.708 1.00 19.04 C ATOM 743 CD LYS A 203 29.110 5.664 -14.817 1.00 19.75 C ATOM 744 CE LYS A 203 27.994 5.642 -15.832 1.00 31.58 C ATOM 745 NZ LYS A 203 28.362 4.897 -17.072 1.00 41.05 N ATOM 746 N ASN A 204 28.319 9.629 -12.039 1.00 17.57 N ATOM 747 CA ASN A 204 28.314 11.043 -12.440 1.00 18.60 C ATOM 748 C ASN A 204 28.264 12.015 -11.269 1.00 21.93 C ATOM 749 O ASN A 204 28.354 13.225 -11.474 1.00 21.83 O ATOM 750 CB ASN A 204 27.175 11.335 -13.429 1.00 17.60 C ATOM 751 CG ASN A 204 27.301 10.535 -14.707 1.00 21.03 C ATOM 752 OD1 ASN A 204 26.318 9.974 -15.215 1.00 24.06 O ATOM 753 ND2 ASN A 204 28.517 10.414 -15.209 1.00 12.67 N ATOM 754 N ASN A 205 28.072 11.493 -10.037 1.00 18.09 N ATOM 755 CA ASN A 205 27.935 12.351 -8.874 1.00 17.59 C ATOM 756 C ASN A 205 29.244 12.310 -8.111 1.00 19.53 C ATOM 757 O ASN A 205 29.510 11.354 -7.372 1.00 18.15 O ATOM 758 CB ASN A 205 26.788 11.856 -8.001 1.00 18.37 C ATOM 759 CG ASN A 205 26.522 12.784 -6.830 1.00 31.19 C ATOM 760 OD1 ASN A 205 27.378 13.600 -6.405 1.00 27.13 O ATOM 761 ND2 ASN A 205 25.305 12.717 -6.325 1.00 28.85 N ATOM 762 N GLU A 206 30.069 13.337 -8.307 1.00 17.18 N ATOM 763 CA GLU A 206 31.398 13.417 -7.705 1.00 16.52 C ATOM 764 C GLU A 206 31.386 13.504 -6.178 1.00 21.12 C ATOM 765 O GLU A 206 32.420 13.257 -5.567 1.00 22.33 O ATOM 766 CB GLU A 206 32.239 14.566 -8.312 1.00 18.03 C ATOM 767 CG GLU A 206 31.716 15.971 -7.989 1.00 23.41 C ATOM 768 CD GLU A 206 30.758 16.564 -9.011 1.00 34.92 C ATOM 769 OE1 GLU A 206 30.959 17.745 -9.380 1.00 24.85 O ATOM 770 OE2 GLU A 206 29.822 15.858 -9.454 1.00 23.51 O ATOM 771 N TYR A 207 30.246 13.904 -5.589 1.00 17.46 N ATOM 772 CA TYR A 207 30.138 14.081 -4.144 1.00 18.20 C ATOM 773 C TYR A 207 29.796 12.764 -3.445 1.00 23.39 C ATOM 774 O TYR A 207 29.834 12.712 -2.225 1.00 23.83 O ATOM 775 CB TYR A 207 29.066 15.142 -3.825 1.00 21.23 C ATOM 776 CG TYR A 207 29.372 16.472 -4.465 1.00 25.17 C ATOM 777 CD1 TYR A 207 30.449 17.244 -4.032 1.00 27.20 C ATOM 778 CD2 TYR A 207 28.667 16.905 -5.587 1.00 26.46 C ATOM 779 CE1 TYR A 207 30.791 18.435 -4.672 1.00 28.74 C ATOM 780 CE2 TYR A 207 28.998 18.098 -6.230 1.00 27.90 C ATOM 781 CZ TYR A 207 30.055 18.864 -5.762 1.00 35.82 C ATOM 782 OH TYR A 207 30.388 20.048 -6.380 1.00 40.18 O ATOM 783 N VAL A 208 29.449 11.714 -4.212 1.00 17.89 N ATOM 784 CA VAL A 208 28.978 10.446 -3.678 1.00 18.77 C ATOM 785 C VAL A 208 29.802 9.231 -4.139 1.00 19.58 C ATOM 786 O VAL A 208 30.031 8.292 -3.371 1.00 18.15 O ATOM 787 CB VAL A 208 27.476 10.332 -4.124 1.00 24.59 C ATOM 788 CG1 VAL A 208 26.940 8.916 -4.022 1.00 24.48 C ATOM 789 CG2 VAL A 208 26.599 11.308 -3.334 1.00 25.59 C ATOM 790 N LYS A 209 30.227 9.241 -5.394 1.00 16.66 N ATOM 791 CA LYS A 209 30.853 8.053 -6.003 1.00 14.79 C ATOM 792 C LYS A 209 32.116 7.517 -5.327 1.00 18.22 C ATOM 793 O LYS A 209 32.422 6.334 -5.499 1.00 18.45 O ATOM 794 CB LYS A 209 31.114 8.300 -7.500 1.00 15.54 C ATOM 795 CG LYS A 209 32.211 9.335 -7.751 1.00 19.11 C ATOM 796 CD LYS A 209 32.553 9.510 -9.257 1.00 24.29 C ATOM 797 CE LYS A 209 33.802 10.345 -9.385 1.00 29.20 C ATOM 798 NZ LYS A 209 34.269 10.466 -10.805 1.00 21.61 N ATOM 799 N ASN A 210 32.865 8.382 -4.621 1.00 17.96 N ATOM 800 CA ASN A 210 34.104 7.982 -3.957 1.00 17.77 C ATOM 801 C ASN A 210 34.004 7.890 -2.441 1.00 20.64 C ATOM 802 O ASN A 210 35.020 7.788 -1.766 1.00 19.07 O ATOM 803 CB ASN A 210 35.270 8.908 -4.348 1.00 17.43 C ATOM 804 CG ASN A 210 35.821 8.557 -5.703 1.00 24.17 C ATOM 805 OD1 ASN A 210 36.003 7.388 -6.033 1.00 25.91 O ATOM 806 ND2 ASN A 210 35.992 9.567 -6.548 1.00 20.15 N ATOM 807 N LEU A 211 32.787 7.940 -1.902 1.00 16.24 N ATOM 808 CA LEU A 211 32.589 7.784 -0.456 1.00 16.48 C ATOM 809 C LEU A 211 33.041 6.383 -0.062 1.00 17.64 C ATOM 810 O LEU A 211 32.974 5.449 -0.871 1.00 17.91 O ATOM 811 CB LEU A 211 31.107 7.960 -0.102 1.00 16.26 C ATOM 812 CG LEU A 211 30.583 9.400 -0.196 1.00 20.48 C ATOM 813 CD1 LEU A 211 29.106 9.428 0.033 1.00 20.36 C ATOM 814 CD2 LEU A 211 31.281 10.332 0.803 1.00 22.82 C ATOM 815 N ASP A 212 33.486 6.221 1.199 1.00 16.70 N ATOM 816 CA ASP A 212 33.850 4.883 1.678 1.00 16.99 C ATOM 817 C ASP A 212 32.569 4.048 1.640 1.00 17.67 C ATOM 818 O ASP A 212 31.470 4.618 1.692 1.00 17.09 O ATOM 819 CB ASP A 212 34.442 4.935 3.087 1.00 18.50 C ATOM 820 CG ASP A 212 33.405 5.301 4.102 1.00 19.42 C ATOM 821 OD1 ASP A 212 33.285 6.507 4.420 1.00 23.78 O ATOM 822 OD2 ASP A 212 32.636 4.392 4.521 1.00 20.17 O ATOM 823 N GLU A 213 32.714 2.723 1.602 1.00 15.40 N ATOM 824 CA GLU A 213 31.574 1.816 1.428 1.00 15.67 C ATOM 825 C GLU A 213 30.437 1.994 2.430 1.00 17.16 C ATOM 826 O GLU A 213 29.260 1.875 2.039 1.00 16.37 O ATOM 827 CB GLU A 213 32.004 0.355 1.307 1.00 17.12 C ATOM 828 CG GLU A 213 32.709 -0.240 2.508 1.00 21.77 C ATOM 829 CD GLU A 213 33.791 -1.185 2.015 1.00 43.75 C ATOM 830 OE1 GLU A 213 33.451 -2.292 1.531 1.00 33.21 O ATOM 831 OE2 GLU A 213 34.964 -0.751 1.977 1.00 34.66 O ATOM 832 N LEU A 214 30.772 2.255 3.729 1.00 13.58 N ATOM 833 CA LEU A 214 29.711 2.426 4.720 1.00 14.12 C ATOM 834 C LEU A 214 28.936 3.723 4.511 1.00 14.84 C ATOM 835 O LEU A 214 27.689 3.713 4.462 1.00 14.94 O ATOM 836 CB LEU A 214 30.217 2.316 6.167 1.00 13.36 C ATOM 837 CG LEU A 214 30.958 1.013 6.508 1.00 16.66 C ATOM 838 CD1 LEU A 214 31.312 0.984 8.012 1.00 15.55 C ATOM 839 CD2 LEU A 214 30.172 -0.219 6.086 1.00 15.20 C ATOM 840 N THR A 215 29.649 4.831 4.283 1.00 13.29 N ATOM 841 CA THR A 215 28.957 6.104 4.058 1.00 13.59 C ATOM 842 C THR A 215 28.134 6.000 2.746 1.00 15.65 C ATOM 843 O THR A 215 26.987 6.442 2.687 1.00 15.23 O ATOM 844 CB THR A 215 29.944 7.279 4.037 1.00 19.03 C ATOM 845 OG1 THR A 215 30.787 7.205 5.206 1.00 17.74 O ATOM 846 CG2 THR A 215 29.208 8.641 3.984 1.00 17.22 C ATOM 847 N LEU A 216 28.723 5.376 1.711 1.00 14.62 N ATOM 848 CA LEU A 216 28.023 5.225 0.439 1.00 14.42 C ATOM 849 C LEU A 216 26.721 4.454 0.622 1.00 16.62 C ATOM 850 O LEU A 216 25.670 4.903 0.142 1.00 15.80 O ATOM 851 CB LEU A 216 28.933 4.568 -0.592 1.00 13.67 C ATOM 852 CG LEU A 216 28.357 4.450 -2.005 1.00 17.78 C ATOM 853 CD1 LEU A 216 27.839 5.773 -2.522 1.00 17.65 C ATOM 854 CD2 LEU A 216 29.420 3.866 -2.928 1.00 20.08 C ATOM 855 N CYS A 217 26.766 3.343 1.400 1.00 12.75 N ATOM 856 CA CYS A 217 25.552 2.555 1.639 1.00 14.56 C ATOM 857 C CYS A 217 24.477 3.393 2.357 1.00 16.93 C ATOM 858 O CYS A 217 23.296 3.345 1.975 1.00 17.43 O ATOM 859 CB CYS A 217 25.912 1.298 2.415 1.00 15.74 C ATOM 860 SG CYS A 217 24.512 0.208 2.765 1.00 19.55 S ATOM 861 N SER A 218 24.893 4.201 3.353 1.00 14.62 N ATOM 862 CA SER A 218 23.987 5.096 4.092 1.00 14.58 C ATOM 863 C SER A 218 23.371 6.123 3.122 1.00 17.03 C ATOM 864 O SER A 218 22.159 6.364 3.169 1.00 18.66 O ATOM 865 CB SER A 218 24.746 5.842 5.186 1.00 15.68 C ATOM 866 OG SER A 218 23.888 6.791 5.791 1.00 17.09 O ATOM 867 N ARG A 219 24.217 6.735 2.268 1.00 14.93 N ATOM 868 CA AARG A 219 23.739 7.741 1.312 0.50 14.31 C ATOM 869 CA BARG A 219 23.759 7.739 1.292 0.50 14.20 C ATOM 870 C ARG A 219 22.808 7.143 0.250 1.00 16.26 C ATOM 871 O ARG A 219 21.786 7.760 -0.098 1.00 16.84 O ATOM 872 CB AARG A 219 24.901 8.531 0.703 0.50 15.28 C ATOM 873 CB BARG A 219 24.947 8.424 0.613 0.50 14.77 C ATOM 874 CG AARG A 219 25.722 9.320 1.738 0.50 17.41 C ATOM 875 CG BARG A 219 25.817 9.225 1.575 0.50 18.90 C ATOM 876 CD AARG A 219 24.924 10.220 2.687 0.50 14.66 C ATOM 877 CD BARG A 219 25.141 10.412 2.251 0.50 20.98 C ATOM 878 NE AARG A 219 25.836 10.900 3.603 0.50 21.84 N ATOM 879 NE BARG A 219 26.129 11.119 3.062 0.50 22.79 N ATOM 880 CZ AARG A 219 26.122 10.495 4.840 0.50 29.10 C ATOM 881 CZ BARG A 219 26.913 12.088 2.608 0.50 35.84 C ATOM 882 NH1AARG A 219 25.467 9.461 5.381 0.50 7.20 N ATOM 883 NH1BARG A 219 26.774 12.536 1.365 0.50 21.89 N ATOM 884 NH2AARG A 219 26.994 11.177 5.581 0.50 17.34 N ATOM 885 NH2BARG A 219 27.819 12.639 3.399 0.50 30.86 N ATOM 886 N HIS A 220 23.111 5.936 -0.204 1.00 14.55 N ATOM 887 CA HIS A 220 22.297 5.202 -1.172 1.00 15.06 C ATOM 888 C HIS A 220 20.903 4.908 -0.557 1.00 20.67 C ATOM 889 O HIS A 220 19.880 5.246 -1.165 1.00 19.13 O ATOM 890 CB HIS A 220 23.006 3.931 -1.621 1.00 15.58 C ATOM 891 CG HIS A 220 22.206 3.128 -2.586 1.00 18.26 C ATOM 892 ND1 HIS A 220 21.863 3.639 -3.831 1.00 20.13 N ATOM 893 CD2 HIS A 220 21.741 1.862 -2.488 1.00 19.64 C ATOM 894 CE1 HIS A 220 21.249 2.655 -4.463 1.00 19.99 C ATOM 895 NE2 HIS A 220 21.117 1.578 -3.681 1.00 20.03 N ATOM 896 N ALA A 221 20.863 4.353 0.682 1.00 16.47 N ATOM 897 CA ALA A 221 19.580 4.108 1.343 1.00 17.16 C ATOM 898 C ALA A 221 18.807 5.451 1.558 1.00 20.39 C ATOM 899 O ALA A 221 17.586 5.508 1.347 1.00 20.65 O ATOM 900 CB ALA A 221 19.823 3.415 2.677 1.00 17.51 C ATOM 901 N GLY A 222 19.538 6.514 1.910 1.00 17.18 N ATOM 902 CA GLY A 222 18.973 7.833 2.165 1.00 16.94 C ATOM 903 C GLY A 222 18.499 8.561 0.914 1.00 21.95 C ATOM 904 O GLY A 222 17.849 9.601 1.020 1.00 22.07 O ATOM 905 N ASN A 223 18.842 8.038 -0.273 1.00 19.20 N ATOM 906 CA ASN A 223 18.476 8.659 -1.554 1.00 20.24 C ATOM 907 C ASN A 223 17.010 8.358 -1.924 1.00 25.04 C ATOM 908 O ASN A 223 16.424 9.085 -2.720 1.00 25.46 O ATOM 909 CB ASN A 223 19.405 8.115 -2.653 1.00 20.76 C ATOM 910 CG ASN A 223 19.384 8.921 -3.943 1.00 32.56 C ATOM 911 OD1 ASN A 223 19.024 10.102 -3.952 1.00 25.62 O ATOM 912 ND2 ASN A 223 19.800 8.305 -5.044 1.00 22.54 N ATOM 913 N MET A 224 16.435 7.287 -1.347 1.00 21.07 N ATOM 914 CA MET A 224 15.115 6.752 -1.703 1.00 20.63 C ATOM 915 C MET A 224 13.986 7.382 -0.923 1.00 25.45 C ATOM 916 O MET A 224 13.673 6.922 0.168 1.00 23.10 O ATOM 917 CB MET A 224 15.113 5.213 -1.600 1.00 21.82 C ATOM 918 CG MET A 224 16.352 4.562 -2.216 1.00 24.57 C ATOM 919 SD MET A 224 16.578 5.116 -3.939 1.00 28.34 S ATOM 920 CE MET A 224 18.133 4.270 -4.346 1.00 25.15 C ATOM 921 N ASN A 225 13.371 8.452 -1.485 1.00 25.25 N ATOM 922 CA ASN A 225 12.281 9.158 -0.803 1.00 26.14 C ATOM 923 C ASN A 225 10.925 8.429 -0.989 1.00 31.21 C ATOM 924 O ASN A 225 10.445 8.319 -2.127 1.00 30.14 O ATOM 925 CB ASN A 225 12.228 10.625 -1.254 1.00 29.81 C ATOM 926 CG ASN A 225 11.289 11.531 -0.492 1.00 40.31 C ATOM 927 OD1 ASN A 225 10.481 11.106 0.334 1.00 32.59 O ATOM 928 ND2 ASN A 225 11.395 12.817 -0.749 1.00 34.21 N ATOM 929 N PRO A 226 10.303 7.912 0.107 1.00 28.74 N ATOM 930 CA PRO A 226 9.019 7.205 -0.043 1.00 28.99 C ATOM 931 C PRO A 226 7.818 8.145 -0.242 1.00 36.28 C ATOM 932 O PRO A 226 6.728 7.678 -0.574 1.00 36.51 O ATOM 933 CB PRO A 226 8.897 6.451 1.281 1.00 30.30 C ATOM 934 CG PRO A 226 9.539 7.372 2.276 1.00 33.32 C ATOM 935 CD PRO A 226 10.722 7.952 1.531 1.00 29.25 C ATOM 936 N ASP A 227 8.009 9.447 0.021 1.00 35.03 N ATOM 937 CA ASP A 227 6.972 10.481 -0.053 1.00 36.26 C ATOM 938 C ASP A 227 6.958 11.170 -1.411 1.00 43.49 C ATOM 939 O ASP A 227 8.016 11.386 -2.010 1.00 42.64 O ATOM 940 CB ASP A 227 7.225 11.535 1.037 1.00 37.59 C ATOM 941 CG ASP A 227 6.037 12.394 1.455 1.00 46.46 C ATOM 942 OD1 ASP A 227 6.176 13.160 2.434 1.00 44.44 O ATOM 943 OD2 ASP A 227 4.975 12.308 0.797 1.00 54.50 O ATOM 944 N LYS A 228 5.755 11.584 -1.855 1.00 42.86 N ATOM 945 CA LYS A 228 5.543 12.326 -3.102 1.00 43.94 C ATOM 946 C LYS A 228 6.116 13.754 -2.984 1.00 49.70 C ATOM 947 O LYS A 228 6.346 14.407 -4.002 1.00 50.52 O ATOM 948 CB LYS A 228 4.045 12.338 -3.475 1.00 46.91 C ATOM 949 CG LYS A 228 3.570 11.132 -4.307 1.00 64.07 C ATOM 950 CD LYS A 228 3.427 9.813 -3.519 1.00 75.63 C ATOM 951 CE LYS A 228 4.564 8.853 -3.800 1.00 86.58 C ATOM 952 NZ LYS A 228 4.535 7.671 -2.899 1.00 95.94 N ATOM 953 N ASP A 229 6.385 14.211 -1.742 1.00 47.15 N ATOM 954 CA ASP A 229 6.969 15.519 -1.428 1.00 47.67 C ATOM 955 C ASP A 229 8.496 15.386 -1.357 1.00 53.66 C ATOM 956 O ASP A 229 9.009 14.582 -0.573 1.00 53.38 O ATOM 957 CB ASP A 229 6.381 16.067 -0.104 1.00 49.46 C ATOM 958 CG ASP A 229 7.069 17.272 0.528 1.00 59.00 C ATOM 959 OD1 ASP A 229 7.004 17.407 1.767 1.00 59.25 O ATOM 960 OD2 ASP A 229 7.636 18.101 -0.219 1.00 67.42 O ATOM 961 N GLU A 230 9.212 16.189 -2.172 1.00 51.74 N ATOM 962 CA GLU A 230 10.678 16.203 -2.263 1.00 51.87 C ATOM 963 C GLU A 230 11.378 16.616 -0.958 1.00 54.74 C ATOM 964 O GLU A 230 12.549 16.275 -0.766 1.00 54.89 O ATOM 965 CB GLU A 230 11.151 17.057 -3.465 1.00 53.43 C ATOM 966 CG GLU A 230 11.628 18.467 -3.129 1.00 66.71 C ATOM 967 CD GLU A 230 11.124 19.576 -4.031 1.00 95.06 C ATOM 968 OE1 GLU A 230 11.453 19.562 -5.240 1.00 92.94 O ATOM 969 OE2 GLU A 230 10.431 20.485 -3.518 1.00 92.20 O ATOM 970 N ASN A 231 10.671 17.352 -0.078 1.00 49.37 N ATOM 971 CA ASN A 231 11.233 17.837 1.181 1.00 48.31 C ATOM 972 C ASN A 231 11.080 16.917 2.400 1.00 47.96 C ATOM 973 O ASN A 231 11.505 17.298 3.499 1.00 47.51 O ATOM 974 CB ASN A 231 10.817 19.283 1.461 1.00 52.66 C ATOM 975 CG ASN A 231 11.609 20.275 0.649 1.00 80.19 C ATOM 976 OD1 ASN A 231 11.234 20.640 -0.473 1.00 75.62 O ATOM 977 ND2 ASN A 231 12.746 20.705 1.183 1.00 71.20 N ATOM 978 N SER A 232 10.526 15.695 2.204 1.00 41.57 N ATOM 979 CA SER A 232 10.397 14.695 3.275 1.00 40.06 C ATOM 980 C SER A 232 11.797 14.277 3.742 1.00 40.73 C ATOM 981 O SER A 232 12.680 14.028 2.914 1.00 40.23 O ATOM 982 CB SER A 232 9.637 13.468 2.786 1.00 42.96 C ATOM 983 OG SER A 232 9.634 12.426 3.751 1.00 49.01 O ATOM 984 N ASN A 233 11.998 14.251 5.063 1.00 34.99 N ATOM 985 CA ASN A 233 13.273 13.898 5.685 1.00 33.14 C ATOM 986 C ASN A 233 13.334 12.413 6.059 1.00 32.06 C ATOM 987 O ASN A 233 14.275 12.000 6.752 1.00 30.70 O ATOM 988 CB ASN A 233 13.533 14.785 6.912 1.00 38.14 C ATOM 989 CG ASN A 233 13.709 16.257 6.603 1.00 69.08 C ATOM 990 OD1 ASN A 233 12.907 17.099 7.021 1.00 68.98 O ATOM 991 ND2 ASN A 233 14.781 16.609 5.900 1.00 59.11 N ATOM 992 N TYR A 234 12.346 11.595 5.597 1.00 25.05 N ATOM 993 CA TYR A 234 12.379 10.176 5.897 1.00 23.26 C ATOM 994 C TYR A 234 13.457 9.490 5.073 1.00 24.77 C ATOM 995 O TYR A 234 13.378 9.443 3.842 1.00 22.92 O ATOM 996 CB TYR A 234 11.023 9.480 5.699 1.00 23.03 C ATOM 997 CG TYR A 234 10.978 8.120 6.368 1.00 23.34 C ATOM 998 CD1 TYR A 234 10.468 7.971 7.659 1.00 24.72 C ATOM 999 CD2 TYR A 234 11.529 6.999 5.752 1.00 23.26 C ATOM 1000 CE1 TYR A 234 10.465 6.730 8.297 1.00 24.33 C ATOM 1001 CE2 TYR A 234 11.524 5.753 6.375 1.00 23.98 C ATOM 1002 CZ TYR A 234 11.005 5.625 7.655 1.00 28.51 C ATOM 1003 OH TYR A 234 11.035 4.403 8.276 1.00 25.99 O ATOM 1004 N LYS A 235 14.463 8.937 5.781 1.00 21.08 N ATOM 1005 CA LYS A 235 15.580 8.255 5.149 1.00 19.26 C ATOM 1006 C LYS A 235 15.785 6.902 5.782 1.00 20.82 C ATOM 1007 O LYS A 235 16.090 6.781 6.998 1.00 18.32 O ATOM 1008 CB LYS A 235 16.840 9.119 5.221 1.00 20.27 C ATOM 1009 CG LYS A 235 16.763 10.391 4.365 1.00 21.09 C ATOM 1010 CD LYS A 235 18.088 11.128 4.388 1.00 25.28 C ATOM 1011 CE LYS A 235 18.037 12.386 3.553 1.00 28.91 C ATOM 1012 NZ LYS A 235 19.337 13.103 3.613 1.00 30.04 N ATOM 1013 N TYR A 236 15.541 5.864 4.964 1.00 18.50 N ATOM 1014 CA TYR A 236 15.663 4.479 5.391 1.00 18.84 C ATOM 1015 C TYR A 236 17.083 4.143 5.912 1.00 20.26 C ATOM 1016 O TYR A 236 18.071 4.628 5.356 1.00 18.17 O ATOM 1017 CB TYR A 236 15.344 3.529 4.226 1.00 20.55 C ATOM 1018 CG TYR A 236 13.889 3.553 3.811 1.00 22.32 C ATOM 1019 CD1 TYR A 236 13.467 4.305 2.716 1.00 24.53 C ATOM 1020 CD2 TYR A 236 12.939 2.798 4.494 1.00 22.84 C ATOM 1021 CE1 TYR A 236 12.119 4.344 2.344 1.00 25.82 C ATOM 1022 CE2 TYR A 236 11.595 2.820 4.126 1.00 23.83 C ATOM 1023 CZ TYR A 236 11.190 3.588 3.047 1.00 31.04 C ATOM 1024 OH TYR A 236 9.848 3.610 2.711 1.00 27.99 O ATOM 1025 N PRO A 237 17.189 3.266 6.936 1.00 17.03 N ATOM 1026 CA PRO A 237 18.523 2.840 7.382 1.00 15.54 C ATOM 1027 C PRO A 237 18.959 1.688 6.465 1.00 19.76 C ATOM 1028 O PRO A 237 18.223 1.286 5.546 1.00 19.04 O ATOM 1029 CB PRO A 237 18.281 2.369 8.817 1.00 17.78 C ATOM 1030 CG PRO A 237 16.876 1.807 8.775 1.00 22.00 C ATOM 1031 CD PRO A 237 16.117 2.618 7.724 1.00 19.13 C ATOM 1032 N ALA A 238 20.152 1.163 6.695 1.00 15.28 N ATOM 1033 CA ALA A 238 20.665 0.089 5.851 1.00 15.14 C ATOM 1034 C ALA A 238 21.602 -0.805 6.631 1.00 16.93 C ATOM 1035 O ALA A 238 22.086 -0.442 7.713 1.00 14.78 O ATOM 1036 CB ALA A 238 21.422 0.684 4.653 1.00 16.41 C ATOM 1037 N VAL A 239 21.874 -1.955 6.052 1.00 15.58 N ATOM 1038 CA VAL A 239 22.883 -2.883 6.539 1.00 15.64 C ATOM 1039 C VAL A 239 23.861 -3.147 5.413 1.00 19.04 C ATOM 1040 O VAL A 239 23.458 -3.514 4.298 1.00 17.35 O ATOM 1041 CB VAL A 239 22.285 -4.202 7.098 1.00 19.26 C ATOM 1042 CG1 VAL A 239 23.377 -5.249 7.347 1.00 19.52 C ATOM 1043 CG2 VAL A 239 21.486 -3.930 8.377 1.00 19.25 C ATOM 1044 N TYR A 240 25.145 -2.973 5.702 1.00 15.27 N ATOM 1045 CA TYR A 240 26.216 -3.292 4.768 1.00 15.87 C ATOM 1046 C TYR A 240 26.768 -4.646 5.183 1.00 19.07 C ATOM 1047 O TYR A 240 27.094 -4.852 6.351 1.00 16.64 O ATOM 1048 CB TYR A 240 27.332 -2.233 4.775 1.00 17.38 C ATOM 1049 CG TYR A 240 28.339 -2.464 3.664 1.00 18.71 C ATOM 1050 CD1 TYR A 240 28.027 -2.158 2.340 1.00 19.64 C ATOM 1051 CD2 TYR A 240 29.602 -2.988 3.935 1.00 18.30 C ATOM 1052 CE1 TYR A 240 28.933 -2.389 1.310 1.00 18.10 C ATOM 1053 CE2 TYR A 240 30.518 -3.237 2.905 1.00 17.98 C ATOM 1054 CZ TYR A 240 30.195 -2.883 1.602 1.00 19.25 C ATOM 1055 OH TYR A 240 31.083 -3.035 0.569 1.00 21.27 O ATOM 1056 N ASP A 241 26.851 -5.586 4.238 1.00 16.15 N ATOM 1057 CA ASP A 241 27.424 -6.890 4.518 1.00 16.34 C ATOM 1058 C ASP A 241 28.860 -6.908 3.957 1.00 19.70 C ATOM 1059 O ASP A 241 29.047 -6.948 2.741 1.00 18.47 O ATOM 1060 CB ASP A 241 26.566 -8.023 3.903 1.00 17.34 C ATOM 1061 CG ASP A 241 27.074 -9.444 4.155 1.00 25.87 C ATOM 1062 OD1 ASP A 241 28.106 -9.603 4.864 1.00 22.29 O ATOM 1063 OD2 ASP A 241 26.399 -10.407 3.704 1.00 29.71 O ATOM 1064 N ASP A 242 29.862 -6.911 4.848 1.00 16.89 N ATOM 1065 CA ASP A 242 31.286 -6.929 4.484 1.00 18.61 C ATOM 1066 C ASP A 242 31.761 -8.206 3.756 1.00 23.70 C ATOM 1067 O ASP A 242 32.748 -8.154 3.009 1.00 24.90 O ATOM 1068 CB ASP A 242 32.173 -6.638 5.714 1.00 21.30 C ATOM 1069 CG ASP A 242 32.815 -5.253 5.732 1.00 40.46 C ATOM 1070 OD1 ASP A 242 32.944 -4.635 4.645 1.00 43.33 O ATOM 1071 OD2 ASP A 242 33.282 -4.830 6.809 1.00 48.14 O ATOM 1072 N LYS A 243 31.071 -9.335 3.961 1.00 21.08 N ATOM 1073 CA LYS A 243 31.433 -10.615 3.327 1.00 21.97 C ATOM 1074 C LYS A 243 31.195 -10.567 1.823 1.00 25.95 C ATOM 1075 O LYS A 243 32.029 -11.049 1.044 1.00 27.32 O ATOM 1076 CB LYS A 243 30.601 -11.769 3.928 1.00 25.51 C ATOM 1077 CG LYS A 243 30.963 -13.146 3.349 1.00 36.29 C ATOM 1078 CD LYS A 243 30.891 -14.256 4.392 1.00 47.98 C ATOM 1079 CE LYS A 243 31.339 -15.591 3.833 1.00 59.03 C ATOM 1080 NZ LYS A 243 32.801 -15.630 3.530 1.00 65.13 N ATOM 1081 N ASP A 244 30.023 -10.048 1.432 1.00 20.47 N ATOM 1082 CA ASP A 244 29.543 -9.998 0.049 1.00 20.86 C ATOM 1083 C ASP A 244 29.711 -8.615 -0.583 1.00 21.66 C ATOM 1084 O ASP A 244 29.416 -8.471 -1.772 1.00 20.39 O ATOM 1085 CB ASP A 244 28.034 -10.333 0.064 1.00 25.02 C ATOM 1086 CG ASP A 244 27.722 -11.719 -0.434 1.00 48.50 C ATOM 1087 OD1 ASP A 244 27.232 -11.839 -1.577 1.00 54.24 O ATOM 1088 OD2 ASP A 244 27.973 -12.691 0.317 1.00 53.61 O ATOM 1089 N LYS A 245 30.104 -7.585 0.227 1.00 17.84 N ATOM 1090 CA LYS A 245 30.236 -6.174 -0.182 1.00 17.06 C ATOM 1091 C LYS A 245 28.895 -5.683 -0.770 1.00 20.35 C ATOM 1092 O LYS A 245 28.849 -5.116 -1.864 1.00 22.70 O ATOM 1093 CB LYS A 245 31.428 -5.949 -1.147 1.00 20.78 C ATOM 1094 CG LYS A 245 32.796 -6.109 -0.473 1.00 30.39 C ATOM 1095 CD LYS A 245 33.914 -5.586 -1.364 1.00 43.22 C ATOM 1096 CE LYS A 245 34.787 -4.539 -0.706 1.00 42.55 C ATOM 1097 NZ LYS A 245 35.657 -3.836 -1.701 1.00 42.18 N ATOM 1098 N LYS A 246 27.803 -5.978 -0.067 1.00 15.91 N ATOM 1099 CA LYS A 246 26.441 -5.621 -0.480 1.00 16.17 C ATOM 1100 C LYS A 246 25.747 -4.709 0.514 1.00 18.18 C ATOM 1101 O LYS A 246 25.786 -4.945 1.729 1.00 17.36 O ATOM 1102 CB LYS A 246 25.580 -6.862 -0.724 1.00 19.63 C ATOM 1103 CG LYS A 246 25.940 -7.580 -2.015 1.00 29.59 C ATOM 1104 CD LYS A 246 25.030 -8.773 -2.203 1.00 34.98 C ATOM 1105 CE LYS A 246 25.407 -9.599 -3.404 1.00 44.59 C ATOM 1106 NZ LYS A 246 24.690 -10.899 -3.378 1.00 49.28 N ATOM 1107 N CYS A 247 25.157 -3.635 -0.020 1.00 15.24 N ATOM 1108 CA CYS A 247 24.361 -2.701 0.752 1.00 16.03 C ATOM 1109 C CYS A 247 22.909 -3.209 0.683 1.00 19.58 C ATOM 1110 O CYS A 247 22.385 -3.385 -0.421 1.00 19.56 O ATOM 1111 CB CYS A 247 24.463 -1.309 0.135 1.00 16.86 C ATOM 1112 SG CYS A 247 23.486 -0.043 0.987 1.00 20.30 S ATOM 1113 N HIS A 248 22.280 -3.453 1.830 1.00 15.49 N ATOM 1114 CA HIS A 248 20.856 -3.810 1.919 1.00 15.48 C ATOM 1115 C HIS A 248 20.096 -2.647 2.529 1.00 20.06 C ATOM 1116 O HIS A 248 20.335 -2.296 3.699 1.00 18.21 O ATOM 1117 CB HIS A 248 20.640 -5.071 2.780 1.00 15.74 C ATOM 1118 CG HIS A 248 21.405 -6.267 2.304 1.00 18.62 C ATOM 1119 ND1 HIS A 248 20.794 -7.268 1.553 1.00 19.76 N ATOM 1120 CD2 HIS A 248 22.709 -6.589 2.485 1.00 18.75 C ATOM 1121 CE1 HIS A 248 21.739 -8.158 1.312 1.00 18.86 C ATOM 1122 NE2 HIS A 248 22.913 -7.790 1.829 1.00 19.23 N ATOM 1123 N ILE A 249 19.158 -2.056 1.763 1.00 17.13 N ATOM 1124 CA ILE A 249 18.345 -0.956 2.304 1.00 16.76 C ATOM 1125 C ILE A 249 17.253 -1.634 3.133 1.00 20.56 C ATOM 1126 O ILE A 249 16.675 -2.635 2.693 1.00 20.85 O ATOM 1127 CB ILE A 249 17.737 -0.035 1.218 1.00 19.35 C ATOM 1128 CG1 ILE A 249 18.813 0.418 0.178 1.00 19.27 C ATOM 1129 CG2 ILE A 249 17.044 1.175 1.875 1.00 18.80 C ATOM 1130 CD1 ILE A 249 18.234 1.248 -1.045 1.00 19.91 C ATOM 1131 N LEU A 250 16.997 -1.115 4.335 1.00 16.89 N ATOM 1132 CA LEU A 250 15.977 -1.710 5.190 1.00 17.50 C ATOM 1133 C LEU A 250 14.676 -0.948 5.026 1.00 22.02 C ATOM 1134 O LEU A 250 14.612 0.250 5.326 1.00 23.79 O ATOM 1135 CB LEU A 250 16.402 -1.720 6.662 1.00 17.25 C ATOM 1136 CG LEU A 250 17.686 -2.484 7.002 1.00 19.70 C ATOM 1137 CD1 LEU A 250 18.048 -2.307 8.476 1.00 19.96 C ATOM 1138 CD2 LEU A 250 17.585 -3.975 6.635 1.00 20.98 C ATOM 1139 N TYR A 251 13.645 -1.658 4.549 1.00 21.03 N ATOM 1140 CA TYR A 251 12.286 -1.134 4.366 1.00 22.52 C ATOM 1141 C TYR A 251 11.647 -0.943 5.748 1.00 25.46 C ATOM 1142 O TYR A 251 10.939 0.039 5.963 1.00 25.35 O ATOM 1143 CB TYR A 251 11.453 -2.128 3.543 1.00 25.80 C ATOM 1144 CG TYR A 251 10.097 -1.599 3.137 1.00 30.07 C ATOM 1145 CD1 TYR A 251 9.913 -0.961 1.915 1.00 32.65 C ATOM 1146 CD2 TYR A 251 8.982 -1.791 3.947 1.00 32.27 C ATOM 1147 CE1 TYR A 251 8.651 -0.517 1.512 1.00 36.30 C ATOM 1148 CE2 TYR A 251 7.720 -1.335 3.564 1.00 33.97 C ATOM 1149 CZ TYR A 251 7.560 -0.695 2.349 1.00 43.92 C ATOM 1150 OH TYR A 251 6.314 -0.240 1.986 1.00 49.28 O ATOM 1151 N ILE A 252 11.940 -1.871 6.675 1.00 21.17 N ATOM 1152 CA ILE A 252 11.492 -1.848 8.074 1.00 20.64 C ATOM 1153 C ILE A 252 12.605 -1.242 8.939 1.00 23.22 C ATOM 1154 O ILE A 252 13.685 -1.824 9.028 1.00 21.65 O ATOM 1155 CB ILE A 252 11.090 -3.275 8.546 1.00 23.63 C ATOM 1156 CG1 ILE A 252 9.899 -3.837 7.713 1.00 24.00 C ATOM 1157 CG2 ILE A 252 10.775 -3.280 10.065 1.00 24.87 C ATOM 1158 CD1 ILE A 252 9.513 -5.309 8.078 1.00 32.00 C ATOM 1159 N ALA A 253 12.341 -0.079 9.550 1.00 21.42 N ATOM 1160 CA ALA A 253 13.299 0.637 10.396 1.00 22.01 C ATOM 1161 C ALA A 253 13.190 0.220 11.878 1.00 24.81 C ATOM 1162 O ALA A 253 14.026 0.618 12.699 1.00 23.16 O ATOM 1163 CB ALA A 253 13.111 2.142 10.251 1.00 22.85 C ATOM 1164 N ALA A 254 12.159 -0.574 12.214 1.00 23.31 N ATOM 1165 CA ALA A 254 11.949 -1.049 13.581 1.00 23.06 C ATOM 1166 C ALA A 254 13.051 -2.032 13.904 1.00 24.83 C ATOM 1167 O ALA A 254 13.530 -2.734 13.005 1.00 24.76 O ATOM 1168 CB ALA A 254 10.580 -1.731 13.706 1.00 23.66 C ATOM 1169 N GLN A 255 13.478 -2.081 15.173 1.00 20.22 N ATOM 1170 CA GLN A 255 14.550 -2.987 15.574 1.00 19.93 C ATOM 1171 C GLN A 255 14.154 -3.953 16.681 1.00 21.48 C ATOM 1172 O GLN A 255 14.812 -4.978 16.839 1.00 21.23 O ATOM 1173 CB GLN A 255 15.830 -2.203 15.944 1.00 20.75 C ATOM 1174 CG GLN A 255 16.356 -1.377 14.774 1.00 18.25 C ATOM 1175 CD GLN A 255 16.766 0.012 15.201 1.00 20.06 C ATOM 1176 OE1 GLN A 255 17.768 0.192 15.891 1.00 18.86 O ATOM 1177 NE2 GLN A 255 16.019 1.035 14.792 1.00 20.65 N ATOM 1178 N GLU A 256 13.111 -3.616 17.469 1.00 21.67 N ATOM 1179 CA GLU A 256 12.668 -4.508 18.543 1.00 22.30 C ATOM 1180 C GLU A 256 11.140 -4.492 18.658 1.00 27.87 C ATOM 1181 O GLU A 256 10.523 -3.434 18.637 1.00 27.12 O ATOM 1182 CB GLU A 256 13.300 -4.129 19.895 1.00 23.86 C ATOM 1183 CG GLU A 256 12.995 -5.154 20.988 1.00 31.36 C ATOM 1184 CD GLU A 256 13.774 -5.046 22.279 1.00 56.03 C ATOM 1185 OE1 GLU A 256 13.847 -3.933 22.848 1.00 57.68 O ATOM 1186 OE2 GLU A 256 14.289 -6.089 22.741 1.00 59.32 O ATOM 1187 N ASN A 257 10.570 -5.674 18.837 1.00 28.42 N ATOM 1188 CA ASN A 257 9.150 -5.891 19.105 1.00 31.38 C ATOM 1189 C ASN A 257 9.170 -7.190 19.913 1.00 41.98 C ATOM 1190 O ASN A 257 9.166 -8.290 19.351 1.00 39.07 O ATOM 1191 CB ASN A 257 8.348 -5.989 17.814 1.00 32.92 C ATOM 1192 CG ASN A 257 6.850 -6.050 18.003 1.00 54.56 C ATOM 1193 OD1 ASN A 257 6.244 -5.226 18.698 1.00 44.33 O ATOM 1194 ND2 ASN A 257 6.217 -7.001 17.334 1.00 45.16 N ATOM 1195 N ASN A 258 9.289 -7.023 21.249 1.00 47.31 N ATOM 1196 CA AASN A 258 9.389 -8.120 22.215 0.50 49.17 C ATOM 1197 CA BASN A 258 9.392 -8.117 22.217 0.50 49.17 C ATOM 1198 C ASN A 258 8.387 -7.952 23.369 1.00 56.84 C ATOM 1199 O ASN A 258 7.698 -6.927 23.455 1.00 57.33 O ATOM 1200 CB AASN A 258 10.837 -8.225 22.738 0.50 51.37 C ATOM 1201 CB BASN A 258 10.840 -8.209 22.747 0.50 51.34 C ATOM 1202 CG AASN A 258 11.567 -9.502 22.363 0.50 80.40 C ATOM 1203 CG BASN A 258 11.593 -9.467 22.356 0.50 80.35 C ATOM 1204 OD1AASN A 258 12.157 -10.176 23.216 0.50 76.55 O ATOM 1205 OD1BASN A 258 12.208 -10.133 23.197 0.50 76.43 O ATOM 1206 ND2AASN A 258 11.580 -9.852 21.081 0.50 72.35 N ATOM 1207 ND2BASN A 258 11.600 -9.809 21.071 0.50 72.34 N ATOM 1208 N GLY A 259 8.301 -8.964 24.230 1.00 58.15 N ATOM 1209 CA GLY A 259 7.392 -8.967 25.372 1.00 59.81 C ATOM 1210 C GLY A 259 6.328 -10.045 25.275 1.00 67.55 C ATOM 1211 O GLY A 259 5.957 -10.443 24.162 1.00 67.35 O ATOM 1212 N PRO A 260 5.812 -10.553 26.422 1.00 66.23 N ATOM 1213 CA PRO A 260 4.786 -11.610 26.349 1.00 70.86 C ATOM 1214 C PRO A 260 3.393 -11.072 26.038 1.00105.08 C ATOM 1215 O PRO A 260 2.754 -11.536 25.098 1.00 71.68 O ATOM 1216 CB PRO A 260 4.864 -12.280 27.721 1.00 72.05 C ATOM 1217 CG PRO A 260 5.377 -11.218 28.640 1.00 75.19 C ATOM 1218 CD PRO A 260 6.134 -10.200 27.822 1.00 69.57 C ATOM 1219 N MET A 273 1.795 -11.926 14.668 1.00 68.93 N ATOM 1220 CA MET A 273 2.835 -11.984 15.696 1.00 68.47 C ATOM 1221 C MET A 273 4.025 -11.051 15.357 1.00 68.04 C ATOM 1222 O MET A 273 3.983 -9.871 15.722 1.00 68.42 O ATOM 1223 CB MET A 273 3.266 -13.447 15.956 1.00 71.38 C ATOM 1224 CG MET A 273 4.179 -13.627 17.169 1.00 75.94 C ATOM 1225 SD MET A 273 3.798 -15.071 18.204 1.00 81.18 S ATOM 1226 CE MET A 273 4.175 -16.432 17.059 1.00 77.89 C ATOM 1227 N PHE A 274 5.053 -11.573 14.641 1.00 59.77 N ATOM 1228 CA PHE A 274 6.287 -10.886 14.231 1.00 56.92 C ATOM 1229 C PHE A 274 7.076 -10.304 15.414 1.00 54.00 C ATOM 1230 O PHE A 274 7.055 -9.094 15.657 1.00 53.07 O ATOM 1231 CB PHE A 274 6.034 -9.857 13.109 1.00 58.70 C ATOM 1232 CG PHE A 274 7.153 -9.656 12.107 1.00 60.28 C ATOM 1233 CD1 PHE A 274 7.524 -8.379 11.703 1.00 63.35 C ATOM 1234 CD2 PHE A 274 7.788 -10.746 11.516 1.00 62.23 C ATOM 1235 CE1 PHE A 274 8.527 -8.193 10.744 1.00 64.22 C ATOM 1236 CE2 PHE A 274 8.793 -10.560 10.561 1.00 65.21 C ATOM 1237 CZ PHE A 274 9.154 -9.285 10.181 1.00 63.36 C ATOM 1238 N CYS A 275 7.729 -11.191 16.175 1.00 46.49 N ATOM 1239 CA CYS A 275 8.560 -10.826 17.319 1.00 45.03 C ATOM 1240 C CYS A 275 10.026 -10.795 16.863 1.00 37.63 C ATOM 1241 O CYS A 275 10.475 -11.687 16.142 1.00 35.77 O ATOM 1242 CB CYS A 275 8.343 -11.777 18.496 1.00 47.46 C ATOM 1243 SG CYS A 275 6.816 -11.465 19.443 1.00 52.74 S ATOM 1244 N PHE A 276 10.752 -9.745 17.240 1.00 27.74 N ATOM 1245 CA PHE A 276 12.148 -9.608 16.807 1.00 24.33 C ATOM 1246 C PHE A 276 12.956 -8.758 17.786 1.00 25.75 C ATOM 1247 O PHE A 276 12.384 -7.962 18.527 1.00 25.83 O ATOM 1248 CB PHE A 276 12.218 -9.035 15.376 1.00 24.67 C ATOM 1249 CG PHE A 276 11.432 -7.764 15.139 1.00 26.08 C ATOM 1250 CD1 PHE A 276 11.999 -6.517 15.391 1.00 26.91 C ATOM 1251 CD2 PHE A 276 10.128 -7.812 14.653 1.00 28.97 C ATOM 1252 CE1 PHE A 276 11.280 -5.341 15.161 1.00 28.21 C ATOM 1253 CE2 PHE A 276 9.402 -6.635 14.434 1.00 31.85 C ATOM 1254 CZ PHE A 276 9.987 -5.404 14.676 1.00 29.66 C ATOM 1255 N ARG A 277 14.282 -8.933 17.790 1.00 22.24 N ATOM 1256 CA ARG A 277 15.155 -8.172 18.689 1.00 21.57 C ATOM 1257 C ARG A 277 16.510 -7.924 18.038 1.00 22.58 C ATOM 1258 O ARG A 277 16.970 -8.758 17.253 1.00 20.93 O ATOM 1259 CB ARG A 277 15.344 -8.918 20.041 1.00 22.02 C ATOM 1260 CG ARG A 277 16.068 -10.259 19.900 1.00 26.07 C ATOM 1261 CD ARG A 277 16.002 -11.133 21.145 1.00 37.08 C ATOM 1262 NE ARG A 277 16.437 -12.504 20.841 1.00 38.92 N ATOM 1263 CZ ARG A 277 17.701 -12.920 20.865 1.00 53.80 C ATOM 1264 NH1 ARG A 277 18.680 -12.082 21.195 1.00 41.24 N ATOM 1265 NH2 ARG A 277 17.998 -14.175 20.554 1.00 42.94 N ATOM 1266 N PRO A 278 17.174 -6.811 18.398 1.00 19.41 N ATOM 1267 CA PRO A 278 18.527 -6.576 17.876 1.00 19.59 C ATOM 1268 C PRO A 278 19.530 -7.437 18.640 1.00 23.68 C ATOM 1269 O PRO A 278 19.310 -7.759 19.822 1.00 24.43 O ATOM 1270 CB PRO A 278 18.760 -5.073 18.134 1.00 20.54 C ATOM 1271 CG PRO A 278 17.882 -4.730 19.273 1.00 25.20 C ATOM 1272 CD PRO A 278 16.739 -5.728 19.306 1.00 20.66 C ATOM 1273 N ALA A 279 20.633 -7.832 17.982 1.00 20.23 N ATOM 1274 CA ALA A 279 21.677 -8.603 18.639 1.00 20.90 C ATOM 1275 C ALA A 279 22.962 -8.559 17.859 1.00 22.07 C ATOM 1276 O ALA A 279 22.977 -8.202 16.679 1.00 20.24 O ATOM 1277 CB ALA A 279 21.237 -10.061 18.784 1.00 22.82 C ATOM 1278 N LYS A 280 24.025 -8.926 18.531 1.00 19.51 N ATOM 1279 CA LYS A 280 25.328 -9.203 17.933 1.00 19.44 C ATOM 1280 C LYS A 280 25.490 -10.709 18.066 1.00 28.93 C ATOM 1281 O LYS A 280 25.520 -11.275 19.156 1.00 32.21 O ATOM 1282 CB LYS A 280 26.447 -8.452 18.610 1.00 19.92 C ATOM 1283 CG LYS A 280 26.331 -6.961 18.379 1.00 25.75 C ATOM 1284 CD LYS A 280 27.680 -6.395 18.483 1.00 19.80 C ATOM 1285 CE LYS A 280 27.670 -4.898 18.442 1.00 17.48 C ATOM 1286 NZ LYS A 280 29.065 -4.427 18.491 1.00 13.74 N ATOM 1287 N ASP A 281 25.443 -11.366 16.950 1.00 29.57 N ATOM 1288 CA ASP A 281 25.480 -12.818 16.870 1.00 28.58 C ATOM 1289 C ASP A 281 26.640 -13.122 15.951 1.00 27.87 C ATOM 1290 O ASP A 281 27.011 -12.260 15.144 1.00 25.37 O ATOM 1291 CB ASP A 281 24.153 -13.292 16.246 1.00 30.57 C ATOM 1292 CG ASP A 281 23.960 -14.796 16.215 1.00 41.74 C ATOM 1293 OD1 ASP A 281 24.508 -15.451 15.290 1.00 39.38 O ATOM 1294 OD2 ASP A 281 23.242 -15.320 17.099 1.00 48.67 O ATOM 1295 N LYS A 282 27.245 -14.311 16.085 1.00 24.05 N ATOM 1296 CA LYS A 282 28.321 -14.743 15.201 1.00 24.16 C ATOM 1297 C LYS A 282 27.871 -14.659 13.748 1.00 24.49 C ATOM 1298 O LYS A 282 28.677 -14.301 12.895 1.00 26.02 O ATOM 1299 CB LYS A 282 28.765 -16.184 15.511 1.00 28.76 C ATOM 1300 CG LYS A 282 30.220 -16.305 15.974 1.00 47.25 C ATOM 1301 CD LYS A 282 30.425 -15.961 17.461 1.00 61.67 C ATOM 1302 CE LYS A 282 30.488 -17.178 18.351 1.00 70.67 C ATOM 1303 NZ LYS A 282 29.760 -16.962 19.629 1.00 78.07 N ATOM 1304 N SER A 283 26.564 -14.910 13.473 1.00 20.44 N ATOM 1305 CA SER A 283 26.088 -14.878 12.090 1.00 20.82 C ATOM 1306 C SER A 283 26.049 -13.429 11.551 1.00 22.52 C ATOM 1307 O SER A 283 26.005 -13.246 10.336 1.00 21.61 O ATOM 1308 CB SER A 283 24.722 -15.549 11.956 1.00 24.54 C ATOM 1309 OG SER A 283 23.677 -14.679 12.356 1.00 34.97 O ATOM 1310 N PHE A 284 26.067 -12.415 12.470 1.00 17.19 N ATOM 1311 CA PHE A 284 26.027 -11.010 12.061 1.00 16.14 C ATOM 1312 C PHE A 284 27.386 -10.288 12.084 1.00 17.69 C ATOM 1313 O PHE A 284 27.419 -9.052 11.875 1.00 16.30 O ATOM 1314 CB PHE A 284 25.079 -10.221 12.985 1.00 17.19 C ATOM 1315 CG PHE A 284 23.643 -10.681 13.093 1.00 18.91 C ATOM 1316 CD1 PHE A 284 22.896 -10.414 14.237 1.00 20.96 C ATOM 1317 CD2 PHE A 284 23.040 -11.398 12.057 1.00 18.98 C ATOM 1318 CE1 PHE A 284 21.553 -10.814 14.322 1.00 22.10 C ATOM 1319 CE2 PHE A 284 21.695 -11.784 12.139 1.00 22.57 C ATOM 1320 CZ PHE A 284 20.965 -11.495 13.274 1.00 21.17 C ATOM 1321 N GLN A 285 28.465 -11.015 12.378 1.00 14.94 N ATOM 1322 CA GLN A 285 29.797 -10.450 12.588 1.00 15.27 C ATOM 1323 C GLN A 285 30.313 -9.574 11.455 1.00 17.62 C ATOM 1324 O GLN A 285 31.081 -8.681 11.734 1.00 16.84 O ATOM 1325 CB GLN A 285 30.836 -11.474 13.042 1.00 18.14 C ATOM 1326 CG GLN A 285 31.194 -12.496 11.951 1.00 20.92 C ATOM 1327 CD GLN A 285 32.119 -13.555 12.484 1.00 31.72 C ATOM 1328 OE1 GLN A 285 33.304 -13.580 12.160 1.00 33.28 O ATOM 1329 NE2 GLN A 285 31.624 -14.391 13.385 1.00 32.07 N ATOM 1330 N ASN A 286 29.903 -9.843 10.207 1.00 13.28 N ATOM 1331 CA ASN A 286 30.316 -9.027 9.051 1.00 14.06 C ATOM 1332 C ASN A 286 29.286 -7.951 8.657 1.00 18.61 C ATOM 1333 O ASN A 286 29.535 -7.197 7.688 1.00 17.39 O ATOM 1334 CB ASN A 286 30.627 -9.942 7.862 1.00 15.86 C ATOM 1335 CG ASN A 286 31.694 -10.947 8.190 1.00 20.24 C ATOM 1336 OD1 ASN A 286 32.755 -10.608 8.703 1.00 19.10 O ATOM 1337 ND2 ASN A 286 31.437 -12.205 7.882 1.00 24.70 N ATOM 1338 N TYR A 287 28.157 -7.862 9.382 1.00 14.77 N ATOM 1339 CA TYR A 287 27.123 -6.866 9.087 1.00 14.53 C ATOM 1340 C TYR A 287 27.482 -5.562 9.778 1.00 16.06 C ATOM 1341 O TYR A 287 28.088 -5.582 10.860 1.00 15.22 O ATOM 1342 CB TYR A 287 25.742 -7.309 9.616 1.00 15.98 C ATOM 1343 CG TYR A 287 25.124 -8.498 8.918 1.00 19.10 C ATOM 1344 CD1 TYR A 287 25.723 -9.066 7.795 1.00 22.70 C ATOM 1345 CD2 TYR A 287 23.927 -9.053 9.374 1.00 21.66 C ATOM 1346 CE1 TYR A 287 25.158 -10.175 7.157 1.00 24.24 C ATOM 1347 CE2 TYR A 287 23.332 -10.127 8.714 1.00 22.95 C ATOM 1348 CZ TYR A 287 23.975 -10.714 7.638 1.00 28.86 C ATOM 1349 OH TYR A 287 23.388 -11.784 7.002 1.00 29.40 O ATOM 1350 N VAL A 288 27.062 -4.435 9.183 1.00 13.27 N ATOM 1351 CA VAL A 288 27.236 -3.119 9.785 1.00 13.14 C ATOM 1352 C VAL A 288 25.897 -2.426 9.672 1.00 16.84 C ATOM 1353 O VAL A 288 25.410 -2.218 8.558 1.00 15.23 O ATOM 1354 CB VAL A 288 28.355 -2.281 9.115 1.00 14.76 C ATOM 1355 CG1 VAL A 288 28.671 -1.069 9.985 1.00 15.10 C ATOM 1356 CG2 VAL A 288 29.619 -3.105 8.897 1.00 16.14 C ATOM 1357 N TYR A 289 25.337 -2.000 10.810 1.00 14.24 N ATOM 1358 CA TYR A 289 24.029 -1.337 10.826 1.00 13.90 C ATOM 1359 C TYR A 289 24.269 0.151 10.655 1.00 16.88 C ATOM 1360 O TYR A 289 25.010 0.768 11.438 1.00 15.38 O ATOM 1361 CB TYR A 289 23.276 -1.643 12.137 1.00 15.57 C ATOM 1362 CG TYR A 289 21.813 -1.240 12.079 1.00 18.99 C ATOM 1363 CD1 TYR A 289 20.839 -2.138 11.656 1.00 20.84 C ATOM 1364 CD2 TYR A 289 21.399 0.016 12.506 1.00 21.38 C ATOM 1365 CE1 TYR A 289 19.485 -1.781 11.619 1.00 21.56 C ATOM 1366 CE2 TYR A 289 20.054 0.399 12.433 1.00 21.79 C ATOM 1367 CZ TYR A 289 19.099 -0.508 12.000 1.00 28.82 C ATOM 1368 OH TYR A 289 17.761 -0.155 11.966 1.00 32.36 O ATOM 1369 N LEU A 290 23.582 0.745 9.659 1.00 14.40 N ATOM 1370 CA LEU A 290 23.804 2.130 9.272 1.00 13.81 C ATOM 1371 C LEU A 290 22.573 3.008 9.272 1.00 17.32 C ATOM 1372 O LEU A 290 21.658 2.743 8.506 1.00 15.89 O ATOM 1373 CB LEU A 290 24.419 2.157 7.842 1.00 13.20 C ATOM 1374 CG LEU A 290 25.679 1.273 7.616 1.00 15.82 C ATOM 1375 CD1 LEU A 290 25.948 1.120 6.132 1.00 15.78 C ATOM 1376 CD2 LEU A 290 26.918 1.901 8.287 1.00 14.52 C ATOM 1377 N SER A 291 22.572 4.100 10.079 1.00 13.83 N ATOM 1378 CA SER A 291 21.451 5.027 10.004 1.00 14.20 C ATOM 1379 C SER A 291 21.716 5.970 8.814 1.00 18.44 C ATOM 1380 O SER A 291 22.839 6.035 8.295 1.00 18.60 O ATOM 1381 CB SER A 291 21.346 5.868 11.275 1.00 15.82 C ATOM 1382 OG SER A 291 22.118 7.057 11.166 1.00 15.89 O ATOM 1383 N LYS A 292 20.735 6.814 8.509 1.00 15.80 N ATOM 1384 CA LYS A 292 20.842 7.881 7.488 1.00 15.64 C ATOM 1385 C LYS A 292 21.923 8.941 7.797 1.00 17.61 C ATOM 1386 O LYS A 292 22.267 9.730 6.909 1.00 17.57 O ATOM 1387 CB LYS A 292 19.479 8.595 7.420 1.00 18.26 C ATOM 1388 CG LYS A 292 19.136 9.375 8.690 1.00 21.05 C ATOM 1389 CD LYS A 292 17.712 9.879 8.695 1.00 29.04 C ATOM 1390 CE LYS A 292 17.549 10.873 9.811 1.00 27.67 C ATOM 1391 NZ LYS A 292 18.266 12.152 9.531 1.00 24.34 N ATOM 1392 N ASN A 293 22.359 9.048 9.085 1.00 15.01 N ATOM 1393 CA ASN A 293 23.294 10.086 9.532 1.00 14.16 C ATOM 1394 C ASN A 293 24.740 9.630 9.646 1.00 15.85 C ATOM 1395 O ASN A 293 25.555 10.417 10.125 1.00 15.45 O ATOM 1396 CB ASN A 293 22.852 10.632 10.890 1.00 14.91 C ATOM 1397 CG ASN A 293 21.635 11.508 10.835 1.00 24.31 C ATOM 1398 OD1 ASN A 293 21.292 12.083 9.791 1.00 20.60 O ATOM 1399 ND2 ASN A 293 20.992 11.663 11.982 1.00 20.77 N ATOM 1400 N VAL A 294 25.073 8.391 9.214 1.00 15.03 N ATOM 1401 CA VAL A 294 26.480 7.938 9.347 1.00 13.53 C ATOM 1402 C VAL A 294 27.434 8.976 8.734 1.00 17.64 C ATOM 1403 O VAL A 294 27.265 9.399 7.581 1.00 16.03 O ATOM 1404 CB VAL A 294 26.700 6.521 8.742 1.00 15.34 C ATOM 1405 CG1 VAL A 294 28.190 6.207 8.582 1.00 14.97 C ATOM 1406 CG2 VAL A 294 26.039 5.466 9.635 1.00 15.75 C ATOM 1407 N VAL A 295 28.420 9.402 9.529 1.00 14.41 N ATOM 1408 CA VAL A 295 29.343 10.455 9.079 1.00 14.38 C ATOM 1409 C VAL A 295 30.377 9.956 8.104 1.00 18.51 C ATOM 1410 O VAL A 295 30.840 8.816 8.196 1.00 17.77 O ATOM 1411 CB VAL A 295 29.979 11.214 10.267 1.00 17.21 C ATOM 1412 CG1 VAL A 295 28.922 12.004 11.023 1.00 17.37 C ATOM 1413 CG2 VAL A 295 30.738 10.244 11.171 1.00 17.13 C ATOM 1414 N ASP A 296 30.754 10.820 7.132 1.00 15.94 N ATOM 1415 CA ASP A 296 31.715 10.379 6.123 1.00 16.03 C ATOM 1416 C ASP A 296 33.140 10.125 6.623 1.00 18.65 C ATOM 1417 O ASP A 296 33.947 9.564 5.893 1.00 21.43 O ATOM 1418 CB ASP A 296 31.702 11.333 4.916 1.00 18.38 C ATOM 1419 CG ASP A 296 32.161 12.761 5.154 1.00 31.67 C ATOM 1420 OD1 ASP A 296 31.804 13.639 4.336 1.00 35.95 O ATOM 1421 OD2 ASP A 296 32.985 12.985 6.079 1.00 31.00 O ATOM 1422 N ASN A 297 33.458 10.550 7.837 1.00 15.27 N ATOM 1423 CA ASN A 297 34.786 10.344 8.404 1.00 15.34 C ATOM 1424 C ASN A 297 34.690 9.432 9.623 1.00 18.85 C ATOM 1425 O ASN A 297 35.477 9.582 10.563 1.00 18.38 O ATOM 1426 CB ASN A 297 35.443 11.694 8.775 1.00 18.82 C ATOM 1427 CG ASN A 297 34.755 12.496 9.861 1.00 23.17 C ATOM 1428 OD1 ASN A 297 35.385 13.318 10.560 1.00 27.49 O ATOM 1429 ND2 ASN A 297 33.453 12.311 10.035 1.00 17.25 N ATOM 1430 N TRP A 298 33.735 8.466 9.601 1.00 16.17 N ATOM 1431 CA TRP A 298 33.604 7.509 10.715 1.00 16.14 C ATOM 1432 C TRP A 298 34.919 6.751 11.035 1.00 20.70 C ATOM 1433 O TRP A 298 35.140 6.366 12.194 1.00 20.84 O ATOM 1434 CB TRP A 298 32.416 6.529 10.499 1.00 15.43 C ATOM 1435 CG TRP A 298 32.616 5.656 9.298 1.00 16.99 C ATOM 1436 CD1 TRP A 298 32.198 5.927 8.028 1.00 19.57 C ATOM 1437 CD2 TRP A 298 33.423 4.468 9.208 1.00 17.36 C ATOM 1438 NE1 TRP A 298 32.671 4.973 7.158 1.00 18.82 N ATOM 1439 CE2 TRP A 298 33.409 4.057 7.852 1.00 20.24 C ATOM 1440 CE3 TRP A 298 34.130 3.684 10.145 1.00 19.67 C ATOM 1441 CZ2 TRP A 298 34.118 2.938 7.395 1.00 20.20 C ATOM 1442 CZ3 TRP A 298 34.804 2.552 9.690 1.00 20.77 C ATOM 1443 CH2 TRP A 298 34.783 2.185 8.338 1.00 21.26 C ATOM 1444 N GLU A 299 35.762 6.509 10.018 1.00 18.88 N ATOM 1445 CA GLU A 299 37.024 5.789 10.182 1.00 21.72 C ATOM 1446 C GLU A 299 37.904 6.503 11.193 1.00 25.00 C ATOM 1447 O GLU A 299 38.565 5.849 11.999 1.00 25.77 O ATOM 1448 CB GLU A 299 37.754 5.666 8.841 1.00 23.63 C ATOM 1449 CG GLU A 299 37.261 4.516 7.989 1.00 38.46 C ATOM 1450 CD GLU A 299 37.594 4.572 6.510 1.00 67.06 C ATOM 1451 OE1 GLU A 299 38.794 4.448 6.168 1.00 74.31 O ATOM 1452 OE2 GLU A 299 36.652 4.695 5.692 1.00 46.70 O ATOM 1453 N LYS A 300 37.836 7.855 11.206 1.00 19.83 N ATOM 1454 CA LYS A 300 38.636 8.685 12.111 1.00 21.48 C ATOM 1455 C LYS A 300 37.936 9.001 13.430 1.00 23.43 C ATOM 1456 O LYS A 300 38.599 9.053 14.467 1.00 25.22 O ATOM 1457 CB LYS A 300 39.077 9.987 11.365 1.00 24.21 C ATOM 1458 CG LYS A 300 39.664 11.116 12.223 1.00 44.15 C ATOM 1459 CD LYS A 300 41.176 11.006 12.355 1.00 59.62 C ATOM 1460 CE LYS A 300 41.720 11.943 13.405 1.00 70.47 C ATOM 1461 NZ LYS A 300 43.202 11.873 13.481 1.00 79.92 N ATOM 1462 N VAL A 301 36.603 9.183 13.418 1.00 17.53 N ATOM 1463 CA VAL A 301 35.904 9.664 14.615 1.00 18.32 C ATOM 1464 C VAL A 301 35.064 8.643 15.398 1.00 21.26 C ATOM 1465 O VAL A 301 34.510 9.010 16.434 1.00 21.49 O ATOM 1466 CB VAL A 301 35.084 10.951 14.325 1.00 22.44 C ATOM 1467 CG1 VAL A 301 35.970 12.079 13.786 1.00 22.75 C ATOM 1468 CG2 VAL A 301 33.898 10.670 13.387 1.00 21.03 C ATOM 1469 N CYS A 302 34.844 7.446 14.838 1.00 17.03 N ATOM 1470 CA CYS A 302 33.977 6.443 15.482 1.00 16.08 C ATOM 1471 C CYS A 302 34.814 5.231 15.915 1.00 15.72 C ATOM 1472 O CYS A 302 35.791 4.887 15.258 1.00 15.22 O ATOM 1473 CB CYS A 302 32.845 6.006 14.541 1.00 17.13 C ATOM 1474 SG CYS A 302 31.644 7.312 14.134 1.00 20.07 S ATOM 1475 N PRO A 303 34.354 4.492 16.938 1.00 15.13 N ATOM 1476 CA PRO A 303 35.062 3.261 17.321 1.00 14.77 C ATOM 1477 C PRO A 303 34.898 2.162 16.268 1.00 18.63 C ATOM 1478 O PRO A 303 33.894 2.111 15.542 1.00 20.79 O ATOM 1479 CB PRO A 303 34.318 2.794 18.588 1.00 17.00 C ATOM 1480 CG PRO A 303 33.591 3.984 19.094 1.00 20.39 C ATOM 1481 CD PRO A 303 33.218 4.774 17.842 1.00 16.31 C ATOM 1482 N ARG A 304 35.875 1.277 16.189 1.00 14.74 N ATOM 1483 CA ARG A 304 35.722 0.072 15.369 1.00 13.12 C ATOM 1484 C ARG A 304 36.451 -1.063 16.074 1.00 17.08 C ATOM 1485 O ARG A 304 35.839 -2.051 16.461 1.00 16.68 O ATOM 1486 CB ARG A 304 36.181 0.228 13.897 1.00 14.81 C ATOM 1487 CG ARG A 304 36.091 -1.114 13.152 1.00 17.32 C ATOM 1488 CD ARG A 304 36.742 -1.094 11.785 1.00 19.95 C ATOM 1489 NE ARG A 304 36.551 -2.423 11.224 1.00 21.61 N ATOM 1490 CZ ARG A 304 35.828 -2.707 10.158 1.00 30.77 C ATOM 1491 NH1 ARG A 304 35.459 -1.738 9.319 1.00 20.22 N ATOM 1492 NH2 ARG A 304 35.597 -3.971 9.832 1.00 23.19 N ATOM 1493 N LYS A 305 37.755 -0.927 16.230 1.00 14.68 N ATOM 1494 CA LYS A 305 38.561 -1.991 16.832 1.00 15.95 C ATOM 1495 C LYS A 305 38.554 -1.959 18.349 1.00 18.67 C ATOM 1496 O LYS A 305 38.420 -0.899 18.975 1.00 17.98 O ATOM 1497 CB LYS A 305 39.995 -1.926 16.290 1.00 20.64 C ATOM 1498 CG LYS A 305 40.054 -2.423 14.825 1.00 21.02 C ATOM 1499 CD LYS A 305 41.406 -2.352 14.252 1.00 31.10 C ATOM 1500 CE LYS A 305 41.336 -2.351 12.746 1.00 31.93 C ATOM 1501 NZ LYS A 305 40.866 -3.651 12.225 1.00 28.93 N ATOM 1502 N ASN A 306 38.625 -3.138 18.938 1.00 15.39 N ATOM 1503 CA ASN A 306 38.802 -3.274 20.381 1.00 14.04 C ATOM 1504 C ASN A 306 40.281 -2.978 20.693 1.00 18.85 C ATOM 1505 O ASN A 306 41.167 -3.279 19.900 1.00 19.65 O ATOM 1506 CB ASN A 306 38.419 -4.668 20.791 1.00 16.34 C ATOM 1507 CG ASN A 306 36.962 -4.896 20.488 1.00 25.39 C ATOM 1508 OD1 ASN A 306 36.109 -4.213 21.034 1.00 20.81 O ATOM 1509 ND2 ASN A 306 36.675 -5.673 19.457 1.00 14.84 N ATOM 1510 N LEU A 307 40.550 -2.379 21.847 1.00 15.55 N ATOM 1511 CA LEU A 307 41.926 -1.984 22.165 1.00 15.59 C ATOM 1512 C LEU A 307 42.589 -3.023 23.075 1.00 18.28 C ATOM 1513 O LEU A 307 42.214 -3.138 24.227 1.00 17.25 O ATOM 1514 CB LEU A 307 41.932 -0.585 22.812 1.00 15.76 C ATOM 1515 CG LEU A 307 41.128 0.510 22.070 1.00 20.74 C ATOM 1516 CD1 LEU A 307 41.163 1.809 22.842 1.00 21.69 C ATOM 1517 CD2 LEU A 307 41.601 0.698 20.621 1.00 23.06 C ATOM 1518 N GLU A 308 43.494 -3.837 22.518 1.00 16.79 N ATOM 1519 CA GLU A 308 44.200 -4.877 23.287 1.00 16.99 C ATOM 1520 C GLU A 308 45.213 -4.239 24.248 1.00 20.22 C ATOM 1521 O GLU A 308 45.830 -3.210 23.938 1.00 19.59 O ATOM 1522 CB GLU A 308 44.937 -5.832 22.334 1.00 19.07 C ATOM 1523 CG GLU A 308 45.269 -7.172 22.950 1.00 27.14 C ATOM 1524 CD GLU A 308 45.735 -8.200 21.933 1.00 34.70 C ATOM 1525 OE1 GLU A 308 45.491 -9.405 22.157 1.00 41.30 O ATOM 1526 OE2 GLU A 308 46.278 -7.798 20.879 1.00 32.18 O ATOM 1527 N ASN A 309 45.388 -4.854 25.428 1.00 16.40 N ATOM 1528 CA ASN A 309 46.338 -4.390 26.438 1.00 16.60 C ATOM 1529 C ASN A 309 45.997 -3.024 26.990 1.00 20.74 C ATOM 1530 O ASN A 309 46.864 -2.280 27.438 1.00 22.45 O ATOM 1531 CB ASN A 309 47.800 -4.474 25.955 1.00 18.75 C ATOM 1532 CG ASN A 309 48.187 -5.854 25.475 1.00 25.83 C ATOM 1533 OD1 ASN A 309 48.079 -6.829 26.208 1.00 25.73 O ATOM 1534 ND2 ASN A 309 48.617 -5.972 24.239 1.00 26.51 N ATOM 1535 N ALA A 310 44.709 -2.679 26.932 1.00 17.97 N ATOM 1536 CA ALA A 310 44.240 -1.392 27.392 1.00 18.51 C ATOM 1537 C ALA A 310 42.929 -1.550 28.128 1.00 19.38 C ATOM 1538 O ALA A 310 42.071 -2.365 27.760 1.00 17.36 O ATOM 1539 CB ALA A 310 44.027 -0.478 26.191 1.00 19.44 C ATOM 1540 N LYS A 311 42.758 -0.699 29.138 1.00 16.95 N ATOM 1541 CA LYS A 311 41.496 -0.603 29.817 1.00 17.29 C ATOM 1542 C LYS A 311 41.134 0.867 29.932 1.00 17.82 C ATOM 1543 O LYS A 311 41.993 1.736 30.134 1.00 20.66 O ATOM 1544 CB LYS A 311 41.440 -1.370 31.162 1.00 22.90 C ATOM 1545 CG LYS A 311 42.043 -0.702 32.369 1.00 28.29 C ATOM 1546 CD LYS A 311 42.030 -1.589 33.651 1.00 26.47 C ATOM 1547 CE LYS A 311 40.691 -1.764 34.330 1.00 45.43 C ATOM 1548 NZ LYS A 311 40.848 -2.205 35.749 1.00 57.97 N ATOM 1549 N PHE A 312 39.851 1.144 29.752 1.00 13.93 N ATOM 1550 CA PHE A 312 39.357 2.496 29.889 1.00 13.70 C ATOM 1551 C PHE A 312 39.437 2.968 31.332 1.00 18.13 C ATOM 1552 O PHE A 312 39.177 2.196 32.259 1.00 17.29 O ATOM 1553 CB PHE A 312 37.887 2.546 29.511 1.00 14.74 C ATOM 1554 CG PHE A 312 37.569 2.336 28.062 1.00 15.49 C ATOM 1555 CD1 PHE A 312 36.636 1.374 27.674 1.00 17.38 C ATOM 1556 CD2 PHE A 312 38.141 3.147 27.082 1.00 15.85 C ATOM 1557 CE1 PHE A 312 36.253 1.259 26.340 1.00 16.35 C ATOM 1558 CE2 PHE A 312 37.788 3.001 25.745 1.00 17.67 C ATOM 1559 CZ PHE A 312 36.830 2.073 25.383 1.00 16.53 C ATOM 1560 N GLY A 313 39.762 4.244 31.491 1.00 16.15 N ATOM 1561 CA GLY A 313 39.811 4.911 32.790 1.00 16.06 C ATOM 1562 C GLY A 313 39.292 6.333 32.717 1.00 19.30 C ATOM 1563 O GLY A 313 38.807 6.777 31.670 1.00 16.86 O ATOM 1564 N LEU A 314 39.425 7.062 33.852 1.00 17.90 N ATOM 1565 CA LEU A 314 39.043 8.457 33.998 1.00 18.96 C ATOM 1566 C LEU A 314 40.282 9.270 34.405 1.00 24.95 C ATOM 1567 O LEU A 314 40.995 8.880 35.333 1.00 23.55 O ATOM 1568 CB LEU A 314 37.926 8.608 35.042 1.00 18.78 C ATOM 1569 CG LEU A 314 36.576 7.964 34.671 1.00 22.07 C ATOM 1570 CD1 LEU A 314 35.621 8.007 35.805 1.00 20.72 C ATOM 1571 CD2 LEU A 314 35.944 8.620 33.444 1.00 22.44 C ATOM 1572 N TRP A 315 40.570 10.342 33.655 1.00 24.13 N ATOM 1573 CA TRP A 315 41.729 11.199 33.925 1.00 25.69 C ATOM 1574 C TRP A 315 41.446 12.096 35.132 1.00 30.43 C ATOM 1575 O TRP A 315 40.448 12.819 35.151 1.00 30.30 O ATOM 1576 CB TRP A 315 42.099 12.021 32.695 1.00 26.39 C ATOM 1577 CG TRP A 315 43.425 12.729 32.813 1.00 29.19 C ATOM 1578 CD1 TRP A 315 43.617 14.062 33.036 1.00 32.63 C ATOM 1579 CD2 TRP A 315 44.731 12.169 32.574 1.00 29.44 C ATOM 1580 NE1 TRP A 315 44.962 14.363 32.986 1.00 32.75 N ATOM 1581 CE2 TRP A 315 45.668 13.224 32.701 1.00 34.08 C ATOM 1582 CE3 TRP A 315 45.204 10.875 32.316 1.00 31.09 C ATOM 1583 CZ2 TRP A 315 47.047 13.023 32.569 1.00 33.43 C ATOM 1584 CZ3 TRP A 315 46.569 10.677 32.162 1.00 32.96 C ATOM 1585 CH2 TRP A 315 47.477 11.743 32.287 1.00 34.18 C ATOM 1586 N VAL A 316 42.290 11.978 36.170 1.00 29.33 N ATOM 1587 CA VAL A 316 42.149 12.731 37.417 1.00 30.52 C ATOM 1588 C VAL A 316 43.537 13.205 37.851 1.00 35.26 C ATOM 1589 O VAL A 316 44.421 12.372 38.053 1.00 33.01 O ATOM 1590 CB VAL A 316 41.474 11.900 38.554 1.00 35.42 C ATOM 1591 CG1 VAL A 316 41.381 12.714 39.838 1.00 36.16 C ATOM 1592 CG2 VAL A 316 40.094 11.378 38.153 1.00 35.16 C ATOM 1593 N ASP A 317 43.717 14.537 37.990 1.00 36.47 N ATOM 1594 CA ASP A 317 44.954 15.173 38.461 1.00 37.60 C ATOM 1595 C ASP A 317 46.240 14.494 37.953 1.00 41.36 C ATOM 1596 O ASP A 317 46.990 13.896 38.734 1.00 42.81 O ATOM 1597 CB ASP A 317 44.934 15.275 39.995 1.00 40.40 C ATOM 1598 N GLY A 318 46.417 14.530 36.636 1.00 36.23 N ATOM 1599 CA GLY A 318 47.577 13.983 35.942 1.00 35.70 C ATOM 1600 C GLY A 318 47.766 12.481 35.927 1.00 37.00 C ATOM 1601 O GLY A 318 48.872 12.030 35.611 1.00 37.74 O ATOM 1602 N ASN A 319 46.700 11.677 36.239 1.00 30.29 N ATOM 1603 CA AASN A 319 46.794 10.213 36.230 0.50 28.70 C ATOM 1604 CA BASN A 319 46.804 10.216 36.214 0.50 28.55 C ATOM 1605 C ASN A 319 45.523 9.554 35.713 1.00 28.85 C ATOM 1606 O ASN A 319 44.436 10.088 35.912 1.00 26.34 O ATOM 1607 CB AASN A 319 47.126 9.667 37.625 0.50 31.94 C ATOM 1608 CB BASN A 319 47.198 9.658 37.589 0.50 30.77 C ATOM 1609 CG AASN A 319 48.599 9.655 37.967 0.50 57.10 C ATOM 1610 CG BASN A 319 47.654 8.216 37.574 0.50 49.40 C ATOM 1611 OD1AASN A 319 49.439 9.120 37.233 0.50 52.00 O ATOM 1612 OD1BASN A 319 48.512 7.809 36.782 0.50 44.52 O ATOM 1613 ND2AASN A 319 48.936 10.191 39.130 0.50 51.38 N ATOM 1614 ND2BASN A 319 47.085 7.409 38.455 0.50 41.95 N ATOM 1615 N CYS A 320 45.661 8.393 35.061 1.00 24.27 N ATOM 1616 CA CYS A 320 44.498 7.666 34.571 1.00 23.85 C ATOM 1617 C CYS A 320 44.046 6.732 35.682 1.00 26.35 C ATOM 1618 O CYS A 320 44.726 5.750 35.995 1.00 28.53 O ATOM 1619 CB CYS A 320 44.794 6.906 33.279 1.00 23.94 C ATOM 1620 SG CYS A 320 43.296 6.300 32.445 1.00 27.02 S ATOM 1621 N GLU A 321 42.915 7.058 36.284 1.00 21.39 N ATOM 1622 CA GLU A 321 42.319 6.275 37.367 1.00 20.28 C ATOM 1623 C GLU A 321 41.317 5.242 36.835 1.00 22.30 C ATOM 1624 O GLU A 321 40.686 5.464 35.791 1.00 19.85 O ATOM 1625 CB GLU A 321 41.609 7.211 38.362 1.00 21.68 C ATOM 1626 CG GLU A 321 42.544 8.211 39.044 1.00 33.72 C ATOM 1627 CD GLU A 321 43.700 7.673 39.878 1.00 50.84 C ATOM 1628 OE1 GLU A 321 43.627 6.518 40.360 1.00 42.90 O ATOM 1629 OE2 GLU A 321 44.681 8.429 40.064 1.00 41.76 O ATOM 1630 N ASP A 322 41.131 4.137 37.581 1.00 19.49 N ATOM 1631 CA ASP A 322 40.144 3.140 37.168 1.00 18.91 C ATOM 1632 C ASP A 322 38.747 3.743 37.194 1.00 19.93 C ATOM 1633 O ASP A 322 38.456 4.616 38.014 1.00 19.92 O ATOM 1634 CB ASP A 322 40.151 1.940 38.140 1.00 21.46 C ATOM 1635 CG ASP A 322 41.176 0.855 37.829 1.00 36.40 C ATOM 1636 OD1 ASP A 322 41.458 0.625 36.631 1.00 38.31 O ATOM 1637 OD2 ASP A 322 41.622 0.170 38.775 1.00 42.05 O ATOM 1638 N ILE A 323 37.847 3.225 36.352 1.00 15.97 N ATOM 1639 CA ILE A 323 36.437 3.592 36.455 1.00 15.93 C ATOM 1640 C ILE A 323 36.012 3.220 37.898 1.00 18.00 C ATOM 1641 O ILE A 323 36.214 2.079 38.344 1.00 18.57 O ATOM 1642 CB ILE A 323 35.586 2.813 35.441 1.00 18.52 C ATOM 1643 CG1 ILE A 323 36.146 2.921 33.993 1.00 18.80 C ATOM 1644 CG2 ILE A 323 34.088 3.208 35.603 1.00 16.70 C ATOM 1645 CD1 ILE A 323 36.120 4.404 33.359 1.00 24.27 C ATOM 1646 N PRO A 324 35.476 4.164 38.694 1.00 17.36 N ATOM 1647 CA PRO A 324 35.223 3.833 40.115 1.00 17.10 C ATOM 1648 C PRO A 324 34.182 2.756 40.394 1.00 18.57 C ATOM 1649 O PRO A 324 34.334 1.985 41.350 1.00 20.40 O ATOM 1650 CB PRO A 324 34.887 5.182 40.772 1.00 18.37 C ATOM 1651 CG PRO A 324 34.649 6.130 39.675 1.00 20.92 C ATOM 1652 CD PRO A 324 35.231 5.586 38.393 1.00 19.28 C ATOM 1653 N HIS A 325 33.124 2.711 39.588 1.00 16.19 N ATOM 1654 CA HIS A 325 32.068 1.729 39.733 1.00 14.69 C ATOM 1655 C HIS A 325 31.769 1.060 38.394 1.00 18.25 C ATOM 1656 O HIS A 325 31.419 1.740 37.421 1.00 16.16 O ATOM 1657 CB HIS A 325 30.807 2.393 40.291 1.00 15.02 C ATOM 1658 CG HIS A 325 29.609 1.517 40.274 1.00 18.22 C ATOM 1659 ND1 HIS A 325 29.546 0.382 41.062 1.00 20.73 N ATOM 1660 CD2 HIS A 325 28.453 1.642 39.583 1.00 21.08 C ATOM 1661 CE1 HIS A 325 28.353 -0.143 40.827 1.00 21.02 C ATOM 1662 NE2 HIS A 325 27.664 0.572 39.937 1.00 21.51 N ATOM 1663 N VAL A 326 31.869 -0.272 38.370 1.00 15.41 N ATOM 1664 CA VAL A 326 31.555 -1.039 37.160 1.00 15.37 C ATOM 1665 C VAL A 326 30.562 -2.165 37.536 1.00 19.10 C ATOM 1666 O VAL A 326 30.460 -2.553 38.707 1.00 17.45 O ATOM 1667 CB VAL A 326 32.821 -1.579 36.449 1.00 17.46 C ATOM 1668 CG1 VAL A 326 33.756 -0.455 36.005 1.00 16.91 C ATOM 1669 CG2 VAL A 326 33.562 -2.605 37.314 1.00 17.34 C ATOM 1670 N ASN A 327 29.883 -2.711 36.531 1.00 15.48 N ATOM 1671 CA ASN A 327 28.888 -3.775 36.665 1.00 14.12 C ATOM 1672 C ASN A 327 29.510 -4.999 36.009 1.00 17.04 C ATOM 1673 O ASN A 327 29.745 -5.002 34.804 1.00 16.79 O ATOM 1674 CB ASN A 327 27.586 -3.399 36.000 1.00 14.54 C ATOM 1675 CG ASN A 327 26.982 -2.164 36.613 1.00 22.35 C ATOM 1676 OD1 ASN A 327 26.377 -2.231 37.664 1.00 20.67 O ATOM 1677 ND2 ASN A 327 27.297 -0.998 36.049 1.00 18.10 N ATOM 1678 N GLU A 328 29.863 -5.978 36.834 1.00 13.72 N ATOM 1679 CA GLU A 328 30.602 -7.145 36.341 1.00 14.70 C ATOM 1680 C GLU A 328 29.688 -8.232 35.834 1.00 19.99 C ATOM 1681 O GLU A 328 28.859 -8.767 36.574 1.00 17.86 O ATOM 1682 CB GLU A 328 31.574 -7.686 37.411 1.00 16.40 C ATOM 1683 CG GLU A 328 32.639 -6.685 37.842 1.00 20.44 C ATOM 1684 CD GLU A 328 33.716 -7.214 38.770 1.00 33.14 C ATOM 1685 OE1 GLU A 328 34.694 -6.475 39.017 1.00 29.24 O ATOM 1686 OE2 GLU A 328 33.572 -8.352 39.271 1.00 20.68 O ATOM 1687 N PHE A 329 29.895 -8.593 34.571 1.00 17.03 N ATOM 1688 CA PHE A 329 29.183 -9.678 33.904 1.00 15.57 C ATOM 1689 C PHE A 329 30.286 -10.663 33.494 1.00 19.88 C ATOM 1690 O PHE A 329 31.321 -10.248 33.008 1.00 22.32 O ATOM 1691 CB PHE A 329 28.464 -9.161 32.642 1.00 15.66 C ATOM 1692 CG PHE A 329 27.220 -8.372 32.975 1.00 16.57 C ATOM 1693 CD1 PHE A 329 27.311 -7.073 33.462 1.00 19.02 C ATOM 1694 CD2 PHE A 329 25.956 -8.941 32.837 1.00 18.21 C ATOM 1695 CE1 PHE A 329 26.162 -6.353 33.795 1.00 20.71 C ATOM 1696 CE2 PHE A 329 24.807 -8.217 33.167 1.00 22.00 C ATOM 1697 CZ PHE A 329 24.917 -6.949 33.693 1.00 20.19 C ATOM 1698 N SER A 330 30.057 -11.937 33.658 1.00 15.99 N ATOM 1699 CA SER A 330 31.055 -12.941 33.233 1.00 14.33 C ATOM 1700 C SER A 330 30.955 -13.120 31.693 1.00 16.42 C ATOM 1701 O SER A 330 29.881 -12.977 31.112 1.00 15.98 O ATOM 1702 CB SER A 330 30.794 -14.259 33.947 1.00 18.28 C ATOM 1703 OG SER A 330 29.419 -14.600 33.855 1.00 16.72 O ATOM 1704 N ALA A 331 32.085 -13.379 31.057 1.00 14.39 N ATOM 1705 CA ALA A 331 32.117 -13.531 29.613 1.00 15.78 C ATOM 1706 C ALA A 331 33.226 -14.466 29.246 1.00 15.91 C ATOM 1707 O ALA A 331 34.365 -14.271 29.664 1.00 16.04 O ATOM 1708 CB ALA A 331 32.352 -12.171 28.965 1.00 16.34 C ATOM 1709 N ASN A 332 32.904 -15.428 28.370 1.00 18.74 N ATOM 1710 CA ASN A 332 33.803 -16.473 27.913 1.00 18.94 C ATOM 1711 C ASN A 332 34.934 -15.937 27.066 1.00 22.43 C ATOM 1712 O ASN A 332 36.051 -16.457 27.115 1.00 22.27 O ATOM 1713 CB ASN A 332 33.009 -17.537 27.159 1.00 22.49 C ATOM 1714 CG ASN A 332 33.818 -18.773 26.842 1.00 48.32 C ATOM 1715 OD1 ASN A 332 34.474 -19.357 27.715 1.00 42.92 O ATOM 1716 ND2 ASN A 332 33.827 -19.165 25.573 1.00 43.03 N ATOM 1717 N ASP A 333 34.642 -14.901 26.272 1.00 17.69 N ATOM 1718 CA ASP A 333 35.636 -14.307 25.390 1.00 17.27 C ATOM 1719 C ASP A 333 35.239 -12.869 25.069 1.00 19.54 C ATOM 1720 O ASP A 333 34.163 -12.420 25.491 1.00 17.45 O ATOM 1721 CB ASP A 333 35.752 -15.157 24.082 1.00 17.90 C ATOM 1722 CG ASP A 333 34.467 -15.375 23.280 1.00 24.62 C ATOM 1723 OD1 ASP A 333 33.508 -14.594 23.447 1.00 20.90 O ATOM 1724 OD2 ASP A 333 34.440 -16.306 22.435 1.00 33.67 O ATOM 1725 N LEU A 334 36.069 -12.169 24.268 1.00 16.29 N ATOM 1726 CA LEU A 334 35.778 -10.781 23.895 1.00 16.01 C ATOM 1727 C LEU A 334 34.429 -10.660 23.157 1.00 18.73 C ATOM 1728 O LEU A 334 33.671 -9.718 23.414 1.00 18.00 O ATOM 1729 CB LEU A 334 36.920 -10.189 23.062 1.00 15.63 C ATOM 1730 CG LEU A 334 36.719 -8.790 22.502 1.00 18.76 C ATOM 1731 CD1 LEU A 334 36.603 -7.740 23.628 1.00 18.29 C ATOM 1732 CD2 LEU A 334 37.843 -8.422 21.544 1.00 16.87 C ATOM 1733 N PHE A 335 34.123 -11.606 22.211 1.00 15.60 N ATOM 1734 CA PHE A 335 32.823 -11.548 21.517 1.00 15.73 C ATOM 1735 C PHE A 335 31.665 -11.487 22.520 1.00 17.79 C ATOM 1736 O PHE A 335 30.762 -10.659 22.388 1.00 16.84 O ATOM 1737 CB PHE A 335 32.631 -12.766 20.595 1.00 17.43 C ATOM 1738 CG PHE A 335 31.708 -12.543 19.412 1.00 20.23 C ATOM 1739 CD1 PHE A 335 32.176 -12.676 18.110 1.00 25.21 C ATOM 1740 CD2 PHE A 335 30.371 -12.218 19.597 1.00 22.86 C ATOM 1741 CE1 PHE A 335 31.325 -12.472 17.010 1.00 26.18 C ATOM 1742 CE2 PHE A 335 29.525 -11.989 18.501 1.00 25.61 C ATOM 1743 CZ PHE A 335 30.006 -12.131 17.214 1.00 25.00 C ATOM 1744 N GLU A 336 31.704 -12.356 23.557 1.00 14.61 N ATOM 1745 CA GLU A 336 30.618 -12.391 24.530 1.00 15.13 C ATOM 1746 C GLU A 336 30.542 -11.114 25.338 1.00 14.98 C ATOM 1747 O GLU A 336 29.449 -10.618 25.580 1.00 16.91 O ATOM 1748 CB GLU A 336 30.743 -13.628 25.434 1.00 17.60 C ATOM 1749 CG GLU A 336 30.429 -14.933 24.709 1.00 26.86 C ATOM 1750 CD GLU A 336 29.176 -14.992 23.855 1.00 57.22 C ATOM 1751 OE1 GLU A 336 29.300 -15.309 22.649 1.00 62.04 O ATOM 1752 OE2 GLU A 336 28.073 -14.724 24.386 1.00 46.34 O ATOM 1753 N CYS A 337 31.688 -10.521 25.632 1.00 13.79 N ATOM 1754 CA CYS A 337 31.706 -9.221 26.327 1.00 15.14 C ATOM 1755 C CYS A 337 31.098 -8.128 25.437 1.00 16.57 C ATOM 1756 O CYS A 337 30.244 -7.366 25.905 1.00 15.70 O ATOM 1757 CB CYS A 337 33.116 -8.853 26.764 1.00 18.31 C ATOM 1758 SG CYS A 337 33.220 -7.242 27.617 1.00 23.87 S ATOM 1759 N ASN A 338 31.524 -8.064 24.147 1.00 12.84 N ATOM 1760 CA ASN A 338 30.996 -7.058 23.230 1.00 13.12 C ATOM 1761 C ASN A 338 29.465 -7.219 23.077 1.00 15.46 C ATOM 1762 O ASN A 338 28.731 -6.226 23.088 1.00 16.64 O ATOM 1763 CB ASN A 338 31.718 -7.138 21.879 1.00 12.87 C ATOM 1764 CG ASN A 338 31.242 -6.049 20.929 1.00 20.39 C ATOM 1765 OD1 ASN A 338 30.320 -6.252 20.133 1.00 16.88 O ATOM 1766 ND2 ASN A 338 31.769 -4.841 21.093 1.00 16.41 N ATOM 1767 N LYS A 339 28.983 -8.485 23.039 1.00 14.18 N ATOM 1768 CA LYS A 339 27.564 -8.780 22.908 1.00 15.51 C ATOM 1769 C LYS A 339 26.778 -8.230 24.146 1.00 18.53 C ATOM 1770 O LYS A 339 25.682 -7.675 24.000 1.00 16.51 O ATOM 1771 CB LYS A 339 27.393 -10.302 22.786 1.00 19.47 C ATOM 1772 CG LYS A 339 25.991 -10.781 22.460 1.00 35.00 C ATOM 1773 CD LYS A 339 25.868 -12.325 22.512 1.00 47.34 C ATOM 1774 CE LYS A 339 26.886 -13.084 21.673 1.00 57.90 C ATOM 1775 NZ LYS A 339 26.297 -13.640 20.429 1.00 66.15 N ATOM 1776 N LEU A 340 27.332 -8.437 25.350 1.00 18.05 N ATOM 1777 CA LEU A 340 26.724 -7.982 26.605 1.00 17.67 C ATOM 1778 C LEU A 340 26.670 -6.469 26.658 1.00 17.43 C ATOM 1779 O LEU A 340 25.610 -5.914 26.957 1.00 15.89 O ATOM 1780 CB LEU A 340 27.470 -8.548 27.833 1.00 17.50 C ATOM 1781 CG LEU A 340 27.310 -10.059 28.068 1.00 21.78 C ATOM 1782 CD1 LEU A 340 28.385 -10.590 29.039 1.00 20.37 C ATOM 1783 CD2 LEU A 340 25.852 -10.418 28.512 1.00 26.25 C ATOM 1784 N VAL A 341 27.800 -5.793 26.300 1.00 13.43 N ATOM 1785 CA VAL A 341 27.828 -4.322 26.276 1.00 12.66 C ATOM 1786 C VAL A 341 26.726 -3.835 25.300 1.00 13.96 C ATOM 1787 O VAL A 341 25.958 -2.919 25.612 1.00 15.27 O ATOM 1788 CB VAL A 341 29.220 -3.753 25.931 1.00 16.69 C ATOM 1789 CG1 VAL A 341 29.165 -2.224 25.788 1.00 17.47 C ATOM 1790 CG2 VAL A 341 30.265 -4.177 26.981 1.00 16.78 C ATOM 1791 N PHE A 342 26.654 -4.447 24.108 1.00 12.98 N ATOM 1792 CA PHE A 342 25.620 -4.098 23.137 1.00 13.23 C ATOM 1793 C PHE A 342 24.213 -4.241 23.741 1.00 16.18 C ATOM 1794 O PHE A 342 23.406 -3.321 23.632 1.00 13.93 O ATOM 1795 CB PHE A 342 25.766 -4.952 21.853 1.00 14.56 C ATOM 1796 CG PHE A 342 24.672 -4.649 20.855 1.00 13.24 C ATOM 1797 CD1 PHE A 342 24.729 -3.503 20.055 1.00 13.51 C ATOM 1798 CD2 PHE A 342 23.546 -5.466 20.761 1.00 14.36 C ATOM 1799 CE1 PHE A 342 23.707 -3.211 19.139 1.00 15.21 C ATOM 1800 CE2 PHE A 342 22.549 -5.203 19.806 1.00 16.12 C ATOM 1801 CZ PHE A 342 22.636 -4.077 18.998 1.00 15.94 C ATOM 1802 N GLU A 343 23.953 -5.368 24.420 1.00 14.34 N ATOM 1803 CA AGLU A 343 22.646 -5.631 25.054 0.50 15.17 C ATOM 1804 CA BGLU A 343 22.646 -5.633 25.049 0.50 15.31 C ATOM 1805 C GLU A 343 22.242 -4.551 26.061 1.00 18.18 C ATOM 1806 O GLU A 343 21.064 -4.191 26.150 1.00 18.72 O ATOM 1807 CB AGLU A 343 22.647 -7.002 25.746 0.50 17.20 C ATOM 1808 CB BGLU A 343 22.651 -7.013 25.719 0.50 17.46 C ATOM 1809 CG AGLU A 343 22.572 -8.177 24.782 0.50 30.74 C ATOM 1810 CG BGLU A 343 22.494 -8.154 24.726 0.50 32.76 C ATOM 1811 CD AGLU A 343 21.230 -8.501 24.147 0.50 52.04 C ATOM 1812 CD BGLU A 343 22.786 -9.551 25.243 0.50 60.10 C ATOM 1813 OE1AGLU A 343 20.243 -7.762 24.372 0.50 39.63 O ATOM 1814 OE1BGLU A 343 23.248 -10.388 24.435 0.50 60.50 O ATOM 1815 OE2AGLU A 343 21.171 -9.522 23.425 0.50 49.33 O ATOM 1816 OE2BGLU A 343 22.526 -9.821 26.439 0.50 55.85 O ATOM 1817 N LEU A 344 23.205 -4.044 26.812 1.00 15.09 N ATOM 1818 CA LEU A 344 22.961 -3.030 27.857 1.00 16.24 C ATOM 1819 C LEU A 344 23.087 -1.607 27.387 1.00 16.06 C ATOM 1820 O LEU A 344 22.807 -0.672 28.163 1.00 17.16 O ATOM 1821 CB LEU A 344 23.988 -3.249 28.977 1.00 16.85 C ATOM 1822 CG LEU A 344 23.924 -4.651 29.629 1.00 22.61 C ATOM 1823 CD1 LEU A 344 24.876 -4.717 30.788 1.00 24.27 C ATOM 1824 CD2 LEU A 344 22.527 -4.928 30.155 1.00 25.53 C ATOM 1825 N SER A 345 23.521 -1.418 26.137 1.00 13.36 N ATOM 1826 CA SER A 345 23.828 -0.074 25.610 1.00 13.03 C ATOM 1827 C SER A 345 22.623 0.866 25.418 1.00 15.07 C ATOM 1828 O SER A 345 21.464 0.451 25.538 1.00 16.82 O ATOM 1829 CB SER A 345 24.616 -0.186 24.307 1.00 15.47 C ATOM 1830 OG SER A 345 23.797 -0.646 23.241 1.00 15.85 O ATOM 1831 N ALA A 346 22.914 2.141 25.041 1.00 14.73 N ATOM 1832 CA ALA A 346 21.911 3.171 24.784 1.00 14.71 C ATOM 1833 C ALA A 346 20.814 2.618 23.903 1.00 16.38 C ATOM 1834 O ALA A 346 21.107 1.948 22.905 1.00 16.40 O ATOM 1835 CB ALA A 346 22.558 4.365 24.098 1.00 14.92 C ATOM 1836 N SER A 347 19.544 2.827 24.319 1.00 15.38 N ATOM 1837 CA SER A 347 18.407 2.269 23.597 1.00 16.24 C ATOM 1838 C SER A 347 17.277 3.260 23.570 1.00 21.04 C ATOM 1839 O SER A 347 16.951 3.878 24.599 1.00 21.95 O ATOM 1840 CB SER A 347 17.959 0.951 24.226 1.00 21.77 C ATOM 1841 OG SER A 347 16.741 0.546 23.622 1.00 27.04 O ATOM 1842 N ASP A 348 16.724 3.459 22.382 1.00 18.12 N ATOM 1843 CA ASP A 348 15.649 4.412 22.146 1.00 18.17 C ATOM 1844 C ASP A 348 14.304 3.717 22.127 1.00 24.37 C ATOM 1845 O ASP A 348 13.312 4.327 21.727 1.00 23.96 O ATOM 1846 CB ASP A 348 15.907 5.150 20.812 1.00 19.63 C ATOM 1847 CG ASP A 348 17.227 5.909 20.770 1.00 18.31 C ATOM 1848 OD1 ASP A 348 17.740 6.270 21.847 1.00 20.62 O ATOM 1849 OD2 ASP A 348 17.692 6.224 19.654 1.00 17.56 O ATOM 1850 N GLN A 349 14.273 2.448 22.550 1.00 24.70 N ATOM 1851 CA GLN A 349 13.069 1.624 22.566 1.00 27.29 C ATOM 1852 C GLN A 349 12.169 2.062 23.710 1.00 35.12 C ATOM 1853 O GLN A 349 12.670 2.179 24.831 1.00 35.10 O ATOM 1854 CB GLN A 349 13.437 0.130 22.728 1.00 29.28 C ATOM 1855 CG GLN A 349 12.269 -0.871 22.559 1.00 36.14 C ATOM 1856 CD GLN A 349 11.690 -0.980 21.155 1.00 41.98 C ATOM 1857 OE1 GLN A 349 12.141 -0.357 20.193 1.00 34.25 O ATOM 1858 NE2 GLN A 349 10.645 -1.767 21.016 1.00 30.92 N ATOM 1859 N PRO A 350 10.837 2.226 23.476 1.00 34.36 N ATOM 1860 CA PRO A 350 9.938 2.606 24.587 1.00 39.32 C ATOM 1861 C PRO A 350 9.737 1.516 25.640 1.00 71.31 C ATOM 1862 O PRO A 350 10.322 0.437 25.552 1.00 44.71 O ATOM 1863 CB PRO A 350 8.621 2.970 23.881 1.00 40.58 C ATOM 1864 CG PRO A 350 8.659 2.286 22.582 1.00 43.28 C ATOM 1865 CD PRO A 350 10.105 2.122 22.193 1.00 37.72 C ATOM 1866 N ASP A 388 10.167 11.701 22.301 1.00 54.28 N ATOM 1867 CA ASP A 388 11.299 12.394 22.918 1.00 53.78 C ATOM 1868 C ASP A 388 11.682 11.815 24.281 1.00 55.47 C ATOM 1869 O ASP A 388 12.867 11.819 24.632 1.00 54.36 O ATOM 1870 CB ASP A 388 11.047 13.909 22.999 1.00 56.00 C ATOM 1871 CG ASP A 388 11.824 14.720 21.974 1.00 70.85 C ATOM 1872 OD1 ASP A 388 11.806 14.345 20.775 1.00 71.51 O ATOM 1873 OD2 ASP A 388 12.428 15.745 22.363 1.00 78.61 O ATOM 1874 N ARG A 389 10.685 11.307 25.043 1.00 50.18 N ATOM 1875 CA ARG A 389 10.912 10.678 26.349 1.00 49.11 C ATOM 1876 C ARG A 389 11.701 9.364 26.212 1.00 49.90 C ATOM 1877 O ARG A 389 12.450 9.005 27.124 1.00 50.68 O ATOM 1878 CB ARG A 389 9.585 10.448 27.112 1.00 51.54 C ATOM 1879 CG ARG A 389 8.522 9.640 26.362 1.00 64.55 C ATOM 1880 N TYR A 390 11.546 8.673 25.060 1.00 42.46 N ATOM 1881 CA TYR A 390 12.195 7.393 24.763 1.00 40.62 C ATOM 1882 C TYR A 390 13.623 7.549 24.222 1.00 38.77 C ATOM 1883 O TYR A 390 14.390 6.584 24.286 1.00 39.52 O ATOM 1884 CB TYR A 390 11.343 6.561 23.780 1.00 42.59 C ATOM 1885 CG TYR A 390 9.874 6.448 24.140 1.00 47.18 C ATOM 1886 CD1 TYR A 390 8.883 6.710 23.197 1.00 49.74 C ATOM 1887 CD2 TYR A 390 9.474 6.091 25.429 1.00 48.65 C ATOM 1888 CE1 TYR A 390 7.530 6.609 23.522 1.00 51.89 C ATOM 1889 CE2 TYR A 390 8.124 5.991 25.766 1.00 49.98 C ATOM 1890 CZ TYR A 390 7.155 6.244 24.807 1.00 59.65 C ATOM 1891 OH TYR A 390 5.823 6.135 25.132 1.00 62.93 O ATOM 1892 N LYS A 391 13.985 8.746 23.717 1.00 28.76 N ATOM 1893 CA LYS A 391 15.312 9.019 23.140 1.00 26.69 C ATOM 1894 C LYS A 391 16.491 9.017 24.147 1.00 28.53 C ATOM 1895 O LYS A 391 16.526 9.824 25.088 1.00 29.02 O ATOM 1896 CB LYS A 391 15.298 10.321 22.336 1.00 27.34 C ATOM 1897 CG LYS A 391 14.472 10.261 21.050 1.00 26.73 C ATOM 1898 CD LYS A 391 14.546 11.618 20.338 1.00 32.78 C ATOM 1899 CE LYS A 391 13.680 11.705 19.093 1.00 43.97 C ATOM 1900 NZ LYS A 391 12.226 11.608 19.386 1.00 45.57 N ATOM 1901 N SER A 392 17.500 8.176 23.896 1.00 21.59 N ATOM 1902 CA SER A 392 18.666 8.095 24.770 1.00 19.38 C ATOM 1903 C SER A 392 19.653 9.203 24.520 1.00 21.22 C ATOM 1904 O SER A 392 20.493 9.499 25.391 1.00 21.66 O ATOM 1905 CB SER A 392 19.383 6.750 24.579 1.00 21.78 C ATOM 1906 OG SER A 392 20.005 6.658 23.302 1.00 21.46 O ATOM 1907 N HIS A 393 19.679 9.713 23.258 1.00 18.00 N ATOM 1908 CA HIS A 393 20.697 10.650 22.794 1.00 18.98 C ATOM 1909 C HIS A 393 22.116 10.055 22.999 1.00 20.49 C ATOM 1910 O HIS A 393 23.100 10.798 23.114 1.00 20.67 O ATOM 1911 CB HIS A 393 20.542 12.057 23.425 1.00 21.65 C ATOM 1912 CG HIS A 393 19.210 12.682 23.118 1.00 27.27 C ATOM 1913 ND1 HIS A 393 18.872 13.077 21.826 1.00 30.28 N ATOM 1914 CD2 HIS A 393 18.162 12.927 23.938 1.00 29.84 C ATOM 1915 CE1 HIS A 393 17.635 13.542 21.907 1.00 29.84 C ATOM 1916 NE2 HIS A 393 17.166 13.469 23.156 1.00 29.99 N ATOM 1917 N GLY A 394 22.195 8.708 23.024 1.00 17.81 N ATOM 1918 CA GLY A 394 23.475 8.035 23.188 1.00 17.02 C ATOM 1919 C GLY A 394 23.888 7.725 24.618 1.00 18.81 C ATOM 1920 O GLY A 394 25.001 7.240 24.825 1.00 16.82 O ATOM 1921 N LYS A 395 23.051 8.074 25.621 1.00 16.23 N ATOM 1922 CA LYS A 395 23.361 7.780 27.022 1.00 15.97 C ATOM 1923 C LYS A 395 23.064 6.315 27.330 1.00 18.65 C ATOM 1924 O LYS A 395 21.975 5.812 27.018 1.00 18.12 O ATOM 1925 CB LYS A 395 22.531 8.668 27.961 1.00 19.05 C ATOM 1926 CG LYS A 395 22.825 10.152 27.832 1.00 21.89 C ATOM 1927 CD LYS A 395 21.844 10.936 28.732 1.00 27.04 C ATOM 1928 CE LYS A 395 21.817 12.413 28.419 1.00 37.77 C ATOM 1929 NZ LYS A 395 23.020 13.106 28.942 1.00 38.41 N ATOM 1930 N GLY A 396 24.025 5.650 27.958 1.00 14.54 N ATOM 1931 CA GLY A 396 23.835 4.276 28.388 1.00 14.75 C ATOM 1932 C GLY A 396 25.115 3.524 28.704 1.00 16.65 C ATOM 1933 O GLY A 396 26.213 4.107 28.790 1.00 15.90 O ATOM 1934 N TYR A 397 24.957 2.203 28.935 1.00 14.09 N ATOM 1935 CA TYR A 397 26.069 1.318 29.258 1.00 13.20 C ATOM 1936 C TYR A 397 26.757 0.955 27.961 1.00 16.48 C ATOM 1937 O TYR A 397 26.554 -0.149 27.431 1.00 15.13 O ATOM 1938 CB TYR A 397 25.578 0.065 30.010 1.00 13.81 C ATOM 1939 CG TYR A 397 25.126 0.420 31.404 1.00 15.52 C ATOM 1940 CD1 TYR A 397 23.796 0.732 31.663 1.00 18.59 C ATOM 1941 CD2 TYR A 397 26.034 0.465 32.462 1.00 15.61 C ATOM 1942 CE1 TYR A 397 23.379 1.111 32.944 1.00 20.68 C ATOM 1943 CE2 TYR A 397 25.629 0.846 33.752 1.00 15.78 C ATOM 1944 CZ TYR A 397 24.294 1.146 33.983 1.00 20.12 C ATOM 1945 OH TYR A 397 23.861 1.483 35.242 1.00 20.19 O ATOM 1946 N ASN A 398 27.528 1.923 27.422 1.00 13.71 N ATOM 1947 CA ASN A 398 28.117 1.751 26.094 1.00 13.32 C ATOM 1948 C ASN A 398 29.533 1.231 26.048 1.00 14.20 C ATOM 1949 O ASN A 398 30.046 0.961 24.948 1.00 13.90 O ATOM 1950 CB ASN A 398 28.072 3.099 25.360 1.00 11.96 C ATOM 1951 CG ASN A 398 26.679 3.691 25.319 1.00 16.01 C ATOM 1952 OD1 ASN A 398 25.697 2.991 25.075 1.00 16.21 O ATOM 1953 ND2 ASN A 398 26.606 5.039 25.410 1.00 15.31 N ATOM 1954 N TRP A 399 30.142 1.041 27.206 1.00 12.29 N ATOM 1955 CA TRP A 399 31.546 0.663 27.283 1.00 11.64 C ATOM 1956 C TRP A 399 31.756 -0.544 28.193 1.00 13.69 C ATOM 1957 O TRP A 399 31.053 -0.698 29.187 1.00 13.24 O ATOM 1958 CB TRP A 399 32.358 1.850 27.868 1.00 12.84 C ATOM 1959 CG TRP A 399 32.168 3.138 27.118 1.00 13.16 C ATOM 1960 CD1 TRP A 399 32.960 3.649 26.128 1.00 15.51 C ATOM 1961 CD2 TRP A 399 31.160 4.131 27.380 1.00 12.76 C ATOM 1962 NE1 TRP A 399 32.495 4.893 25.743 1.00 14.20 N ATOM 1963 CE2 TRP A 399 31.388 5.209 26.484 1.00 14.58 C ATOM 1964 CE3 TRP A 399 30.084 4.218 28.281 1.00 14.22 C ATOM 1965 CZ2 TRP A 399 30.559 6.344 26.451 1.00 14.81 C ATOM 1966 CZ3 TRP A 399 29.285 5.352 28.276 1.00 15.34 C ATOM 1967 CH2 TRP A 399 29.507 6.391 27.349 1.00 15.17 C ATOM 1968 N GLY A 400 32.808 -1.307 27.899 1.00 12.24 N ATOM 1969 CA GLY A 400 33.206 -2.433 28.744 1.00 12.48 C ATOM 1970 C GLY A 400 34.714 -2.575 28.725 1.00 16.95 C ATOM 1971 O GLY A 400 35.354 -2.320 27.695 1.00 16.55 O ATOM 1972 N ASN A 401 35.266 -2.994 29.852 1.00 13.01 N ATOM 1973 CA ASN A 401 36.669 -3.368 30.009 1.00 13.23 C ATOM 1974 C ASN A 401 36.628 -4.880 30.156 1.00 17.41 C ATOM 1975 O ASN A 401 36.082 -5.382 31.153 1.00 15.01 O ATOM 1976 CB ASN A 401 37.293 -2.736 31.257 1.00 15.11 C ATOM 1977 CG ASN A 401 37.699 -1.304 31.014 1.00 19.71 C ATOM 1978 OD1 ASN A 401 38.074 -0.950 29.892 1.00 17.94 O ATOM 1979 ND2 ASN A 401 37.602 -0.455 32.050 1.00 17.75 N ATOM 1980 N TYR A 402 37.147 -5.605 29.163 1.00 14.40 N ATOM 1981 CA TYR A 402 37.153 -7.063 29.258 1.00 13.76 C ATOM 1982 C TYR A 402 38.429 -7.570 29.900 1.00 17.20 C ATOM 1983 O TYR A 402 39.529 -7.374 29.367 1.00 15.87 O ATOM 1984 CB TYR A 402 36.951 -7.717 27.874 1.00 14.49 C ATOM 1985 CG TYR A 402 36.964 -9.223 27.925 1.00 16.18 C ATOM 1986 CD1 TYR A 402 36.048 -9.918 28.710 1.00 18.23 C ATOM 1987 CD2 TYR A 402 37.883 -9.962 27.178 1.00 17.85 C ATOM 1988 CE1 TYR A 402 36.076 -11.305 28.798 1.00 21.54 C ATOM 1989 CE2 TYR A 402 37.883 -11.362 27.216 1.00 19.56 C ATOM 1990 CZ TYR A 402 36.996 -12.024 28.058 1.00 25.29 C ATOM 1991 OH TYR A 402 36.964 -13.399 28.176 1.00 26.27 O ATOM 1992 N ASN A 403 38.291 -8.271 31.046 1.00 15.75 N ATOM 1993 CA ASN A 403 39.490 -8.842 31.645 1.00 14.90 C ATOM 1994 C ASN A 403 39.580 -10.275 31.088 1.00 18.24 C ATOM 1995 O ASN A 403 38.738 -11.123 31.413 1.00 18.57 O ATOM 1996 CB ASN A 403 39.412 -8.852 33.184 1.00 18.05 C ATOM 1997 CG ASN A 403 40.711 -9.319 33.815 1.00 21.53 C ATOM 1998 OD1 ASN A 403 41.332 -10.267 33.347 1.00 18.95 O ATOM 1999 ND2 ASN A 403 41.091 -8.718 34.934 1.00 19.04 N ATOM 2000 N ARG A 404 40.551 -10.517 30.198 1.00 16.32 N ATOM 2001 CA ARG A 404 40.694 -11.815 29.535 1.00 18.34 C ATOM 2002 C ARG A 404 41.241 -12.909 30.473 1.00 22.58 C ATOM 2003 O ARG A 404 41.120 -14.082 30.147 1.00 23.02 O ATOM 2004 CB ARG A 404 41.530 -11.680 28.253 1.00 20.12 C ATOM 2005 CG ARG A 404 43.025 -11.597 28.536 1.00 22.45 C ATOM 2006 CD ARG A 404 43.749 -11.260 27.263 1.00 39.45 C ATOM 2007 NE ARG A 404 44.188 -9.875 27.291 1.00 44.45 N ATOM 2008 CZ ARG A 404 44.716 -9.232 26.256 1.00 52.51 C ATOM 2009 NH1 ARG A 404 44.850 -9.847 25.075 1.00 31.15 N ATOM 2010 NH2 ARG A 404 45.108 -7.965 26.386 1.00 21.66 N ATOM 2011 N LYS A 405 41.817 -12.523 31.632 1.00 19.83 N ATOM 2012 CA LYS A 405 42.340 -13.495 32.602 1.00 19.68 C ATOM 2013 C LYS A 405 41.232 -13.987 33.533 1.00 22.66 C ATOM 2014 O LYS A 405 41.127 -15.190 33.783 1.00 23.10 O ATOM 2015 CB LYS A 405 43.492 -12.897 33.440 1.00 22.56 C ATOM 2016 CG LYS A 405 44.809 -12.799 32.686 1.00 40.64 C ATOM 2017 N THR A 406 40.414 -13.056 34.067 1.00 18.71 N ATOM 2018 CA THR A 406 39.327 -13.413 34.984 1.00 17.86 C ATOM 2019 C THR A 406 38.001 -13.638 34.222 1.00 15.91 C ATOM 2020 O THR A 406 37.013 -14.058 34.818 1.00 15.60 O ATOM 2021 CB THR A 406 39.151 -12.314 36.052 1.00 18.85 C ATOM 2022 OG1 THR A 406 38.787 -11.106 35.378 1.00 19.34 O ATOM 2023 CG2 THR A 406 40.408 -12.113 36.905 1.00 21.93 C ATOM 2024 N HIS A 407 37.969 -13.376 32.887 1.00 13.57 N ATOM 2025 CA HIS A 407 36.761 -13.626 32.060 1.00 14.94 C ATOM 2026 C HIS A 407 35.577 -12.811 32.571 1.00 17.45 C ATOM 2027 O HIS A 407 34.479 -13.341 32.778 1.00 16.11 O ATOM 2028 CB HIS A 407 36.384 -15.129 32.018 1.00 17.38 C ATOM 2029 CG HIS A 407 37.436 -15.961 31.365 1.00 23.00 C ATOM 2030 ND1 HIS A 407 37.467 -16.120 29.991 1.00 27.07 N ATOM 2031 CD2 HIS A 407 38.529 -16.546 31.900 1.00 26.62 C ATOM 2032 CE1 HIS A 407 38.562 -16.818 29.735 1.00 26.61 C ATOM 2033 NE2 HIS A 407 39.244 -17.081 30.839 1.00 27.00 N ATOM 2034 N LYS A 408 35.841 -11.523 32.816 1.00 16.62 N ATOM 2035 CA LYS A 408 34.874 -10.553 33.347 1.00 16.04 C ATOM 2036 C LYS A 408 34.717 -9.401 32.367 1.00 18.63 C ATOM 2037 O LYS A 408 35.709 -8.830 31.927 1.00 20.78 O ATOM 2038 CB LYS A 408 35.359 -9.987 34.696 1.00 17.10 C ATOM 2039 CG LYS A 408 35.416 -10.997 35.851 1.00 20.81 C ATOM 2040 CD LYS A 408 35.601 -10.246 37.138 1.00 22.84 C ATOM 2041 CE LYS A 408 35.577 -11.128 38.344 1.00 25.75 C ATOM 2042 NZ LYS A 408 35.643 -10.324 39.604 1.00 26.79 N ATOM 2043 N CYS A 409 33.481 -9.017 32.116 1.00 16.13 N ATOM 2044 CA CYS A 409 33.119 -7.866 31.280 1.00 17.33 C ATOM 2045 C CYS A 409 32.680 -6.740 32.275 1.00 20.81 C ATOM 2046 O CYS A 409 31.616 -6.844 32.902 1.00 21.35 O ATOM 2047 CB CYS A 409 32.001 -8.281 30.318 1.00 20.82 C ATOM 2048 SG CYS A 409 31.685 -7.089 28.997 1.00 26.58 S ATOM 2049 N GLU A 410 33.567 -5.726 32.517 1.00 14.08 N ATOM 2050 CA GLU A 410 33.305 -4.655 33.496 1.00 12.76 C ATOM 2051 C GLU A 410 32.607 -3.545 32.743 1.00 15.96 C ATOM 2052 O GLU A 410 33.254 -2.821 31.988 1.00 15.87 O ATOM 2053 CB GLU A 410 34.633 -4.194 34.115 1.00 14.35 C ATOM 2054 CG GLU A 410 35.311 -5.332 34.894 1.00 20.94 C ATOM 2055 CD GLU A 410 36.766 -5.108 35.267 1.00 35.23 C ATOM 2056 OE1 GLU A 410 37.454 -6.107 35.577 1.00 35.24 O ATOM 2057 OE2 GLU A 410 37.218 -3.940 35.264 1.00 28.22 O ATOM 2058 N ILE A 411 31.284 -3.499 32.836 1.00 13.17 N ATOM 2059 CA ILE A 411 30.431 -2.622 32.019 1.00 10.78 C ATOM 2060 C ILE A 411 30.080 -1.359 32.768 1.00 13.86 C ATOM 2061 O ILE A 411 29.741 -1.419 33.947 1.00 15.02 O ATOM 2062 CB ILE A 411 29.175 -3.389 31.538 1.00 13.31 C ATOM 2063 CG1 ILE A 411 29.609 -4.689 30.771 1.00 13.80 C ATOM 2064 CG2 ILE A 411 28.294 -2.518 30.630 1.00 15.17 C ATOM 2065 CD1 ILE A 411 28.493 -5.502 30.172 1.00 18.35 C ATOM 2066 N PHE A 412 30.160 -0.201 32.058 1.00 12.24 N ATOM 2067 CA PHE A 412 29.902 1.080 32.743 1.00 11.29 C ATOM 2068 C PHE A 412 29.222 2.085 31.808 1.00 16.71 C ATOM 2069 O PHE A 412 29.166 1.865 30.592 1.00 13.99 O ATOM 2070 CB PHE A 412 31.216 1.605 33.374 1.00 12.68 C ATOM 2071 CG PHE A 412 32.338 1.856 32.394 1.00 12.74 C ATOM 2072 CD1 PHE A 412 32.530 3.117 31.849 1.00 13.77 C ATOM 2073 CD2 PHE A 412 33.178 0.815 31.980 1.00 15.02 C ATOM 2074 CE1 PHE A 412 33.574 3.361 30.955 1.00 14.13 C ATOM 2075 CE2 PHE A 412 34.225 1.052 31.079 1.00 16.62 C ATOM 2076 CZ PHE A 412 34.392 2.322 30.531 1.00 14.76 C ATOM 2077 N ASN A 413 28.647 3.155 32.394 1.00 13.56 N ATOM 2078 CA ASN A 413 27.822 4.085 31.638 1.00 13.57 C ATOM 2079 C ASN A 413 28.286 5.557 31.668 1.00 15.40 C ATOM 2080 O ASN A 413 27.512 6.429 31.357 1.00 15.41 O ATOM 2081 CB ASN A 413 26.347 3.944 32.051 1.00 14.67 C ATOM 2082 CG ASN A 413 26.135 4.353 33.507 1.00 17.19 C ATOM 2083 OD1 ASN A 413 27.088 4.487 34.275 1.00 15.29 O ATOM 2084 ND2 ASN A 413 24.889 4.484 33.896 1.00 14.76 N ATOM 2085 N VAL A 414 29.542 5.785 31.986 1.00 13.27 N ATOM 2086 CA VAL A 414 30.140 7.117 31.936 1.00 14.48 C ATOM 2087 C VAL A 414 31.237 7.105 30.903 1.00 16.76 C ATOM 2088 O VAL A 414 31.953 6.099 30.752 1.00 16.00 O ATOM 2089 CB VAL A 414 30.624 7.602 33.325 1.00 17.04 C ATOM 2090 CG1 VAL A 414 29.424 7.693 34.280 1.00 18.56 C ATOM 2091 CG2 VAL A 414 31.717 6.669 33.895 1.00 15.59 C ATOM 2092 N LYS A 415 31.383 8.221 30.148 1.00 15.62 N ATOM 2093 CA LYS A 415 32.405 8.157 29.113 1.00 15.31 C ATOM 2094 C LYS A 415 33.820 8.061 29.677 1.00 16.47 C ATOM 2095 O LYS A 415 34.143 8.746 30.651 1.00 16.23 O ATOM 2096 CB LYS A 415 32.317 9.333 28.110 1.00 16.69 C ATOM 2097 CG LYS A 415 32.680 10.664 28.725 1.00 19.43 C ATOM 2098 CD LYS A 415 32.963 11.694 27.652 1.00 22.54 C ATOM 2099 CE LYS A 415 33.392 12.990 28.297 1.00 22.72 C ATOM 2100 NZ LYS A 415 33.701 14.027 27.266 1.00 30.10 N ATOM 2101 N PRO A 416 34.660 7.225 29.065 1.00 14.46 N ATOM 2102 CA PRO A 416 36.058 7.124 29.521 1.00 13.90 C ATOM 2103 C PRO A 416 36.877 8.294 28.963 1.00 17.58 C ATOM 2104 O PRO A 416 36.577 8.808 27.877 1.00 16.79 O ATOM 2105 CB PRO A 416 36.505 5.772 28.952 1.00 15.09 C ATOM 2106 CG PRO A 416 35.738 5.654 27.691 1.00 17.52 C ATOM 2107 CD PRO A 416 34.399 6.305 27.931 1.00 13.85 C ATOM 2108 N THR A 417 37.884 8.743 29.732 1.00 16.33 N ATOM 2109 CA THR A 417 38.686 9.921 29.362 1.00 16.52 C ATOM 2110 C THR A 417 40.169 9.643 29.248 1.00 21.83 C ATOM 2111 O THR A 417 40.936 10.562 28.965 1.00 22.75 O ATOM 2112 CB THR A 417 38.358 11.123 30.298 1.00 21.73 C ATOM 2113 OG1 THR A 417 38.651 10.751 31.643 1.00 20.43 O ATOM 2114 CG2 THR A 417 36.895 11.585 30.171 1.00 20.45 C ATOM 2115 N CYS A 418 40.574 8.378 29.389 1.00 19.06 N ATOM 2116 CA CYS A 418 41.964 7.957 29.209 1.00 19.68 C ATOM 2117 C CYS A 418 42.023 6.436 29.099 1.00 21.71 C ATOM 2118 O CYS A 418 41.002 5.747 29.283 1.00 18.93 O ATOM 2119 CB CYS A 418 42.852 8.471 30.346 1.00 21.04 C ATOM 2120 SG CYS A 418 42.285 7.996 31.992 1.00 25.45 S ATOM 2121 N LEU A 419 43.221 5.931 28.817 1.00 17.83 N ATOM 2122 CA LEU A 419 43.480 4.490 28.791 1.00 18.45 C ATOM 2123 C LEU A 419 44.582 4.159 29.774 1.00 22.83 C ATOM 2124 O LEU A 419 45.526 4.943 29.947 1.00 22.62 O ATOM 2125 CB LEU A 419 43.962 4.019 27.415 1.00 18.48 C ATOM 2126 CG LEU A 419 43.077 4.226 26.208 1.00 22.90 C ATOM 2127 CD1 LEU A 419 43.759 3.611 24.996 1.00 23.49 C ATOM 2128 CD2 LEU A 419 41.701 3.522 26.405 1.00 20.42 C ATOM 2129 N ILE A 420 44.488 2.963 30.354 1.00 18.55 N ATOM 2130 CA ILE A 420 45.496 2.377 31.234 1.00 18.79 C ATOM 2131 C ILE A 420 46.090 1.205 30.469 1.00 22.06 C ATOM 2132 O ILE A 420 45.331 0.394 29.942 1.00 21.65 O ATOM 2133 CB ILE A 420 44.874 1.892 32.569 1.00 21.88 C ATOM 2134 CG1 ILE A 420 44.322 3.079 33.389 1.00 23.12 C ATOM 2135 CG2 ILE A 420 45.920 1.133 33.389 1.00 24.31 C ATOM 2136 CD1 ILE A 420 43.138 2.708 34.335 1.00 30.06 C ATOM 2137 N ASN A 421 47.435 1.100 30.421 1.00 19.75 N ATOM 2138 CA ASN A 421 48.103 -0.006 29.744 1.00 20.44 C ATOM 2139 C ASN A 421 48.094 -1.196 30.703 1.00 26.44 C ATOM 2140 O ASN A 421 48.754 -1.160 31.742 1.00 27.98 O ATOM 2141 CB ASN A 421 49.543 0.373 29.328 1.00 24.10 C ATOM 2142 CG ASN A 421 50.205 -0.587 28.362 1.00 43.77 C ATOM 2143 OD1 ASN A 421 49.573 -1.456 27.737 1.00 37.62 O ATOM 2144 ND2 ASN A 421 51.507 -0.437 28.198 1.00 34.25 N ATOM 2145 N ASP A 422 47.246 -2.185 30.423 1.00 21.97 N ATOM 2146 CA ASP A 422 47.106 -3.356 31.285 1.00 20.23 C ATOM 2147 C ASP A 422 46.953 -4.560 30.383 1.00 23.08 C ATOM 2148 O ASP A 422 45.944 -4.690 29.690 1.00 20.55 O ATOM 2149 CB ASP A 422 45.905 -3.217 32.246 1.00 21.42 C ATOM 2150 CG ASP A 422 45.865 -4.295 33.334 1.00 27.37 C ATOM 2151 OD1 ASP A 422 46.221 -5.458 33.038 1.00 27.07 O ATOM 2152 OD2 ASP A 422 45.489 -3.972 34.482 1.00 29.17 O ATOM 2153 N LYS A 423 47.947 -5.463 30.427 1.00 20.93 N ATOM 2154 CA LYS A 423 47.986 -6.656 29.576 1.00 20.83 C ATOM 2155 C LYS A 423 46.834 -7.651 29.753 1.00 22.57 C ATOM 2156 O LYS A 423 46.607 -8.491 28.874 1.00 22.96 O ATOM 2157 CB LYS A 423 49.355 -7.348 29.662 1.00 25.19 C ATOM 2158 CG LYS A 423 50.457 -6.542 28.967 1.00 39.32 C ATOM 2159 CD LYS A 423 51.806 -7.255 28.999 1.00 52.27 C ATOM 2160 CE LYS A 423 52.867 -6.532 28.201 1.00 69.82 C ATOM 2161 NZ LYS A 423 52.753 -6.803 26.741 1.00 80.36 N ATOM 2162 N SER A 424 46.111 -7.564 30.890 1.00 19.99 N ATOM 2163 CA SER A 424 44.982 -8.451 31.121 1.00 18.88 C ATOM 2164 C SER A 424 43.704 -7.937 30.470 1.00 19.28 C ATOM 2165 O SER A 424 42.702 -8.634 30.514 1.00 18.86 O ATOM 2166 CB SER A 424 44.733 -8.606 32.621 1.00 23.81 C ATOM 2167 OG SER A 424 45.867 -9.168 33.263 1.00 30.57 O ATOM 2168 N TYR A 425 43.712 -6.713 29.899 1.00 16.43 N ATOM 2169 CA TYR A 425 42.477 -6.115 29.425 1.00 14.83 C ATOM 2170 C TYR A 425 42.371 -5.827 27.945 1.00 15.60 C ATOM 2171 O TYR A 425 43.374 -5.667 27.235 1.00 15.13 O ATOM 2172 CB TYR A 425 42.254 -4.796 30.175 1.00 16.14 C ATOM 2173 CG TYR A 425 41.691 -5.007 31.559 1.00 15.90 C ATOM 2174 CD1 TYR A 425 42.529 -5.151 32.657 1.00 17.87 C ATOM 2175 CD2 TYR A 425 40.312 -5.075 31.770 1.00 16.21 C ATOM 2176 CE1 TYR A 425 42.011 -5.382 33.936 1.00 18.28 C ATOM 2177 CE2 TYR A 425 39.785 -5.297 33.037 1.00 17.40 C ATOM 2178 CZ TYR A 425 40.634 -5.456 34.118 1.00 25.64 C ATOM 2179 OH TYR A 425 40.085 -5.678 35.361 1.00 25.12 O ATOM 2180 N ILE A 426 41.129 -5.783 27.481 1.00 13.44 N ATOM 2181 CA ILE A 426 40.755 -5.349 26.130 1.00 13.17 C ATOM 2182 C ILE A 426 39.597 -4.343 26.333 1.00 17.13 C ATOM 2183 O ILE A 426 38.599 -4.687 26.961 1.00 16.62 O ATOM 2184 CB ILE A 426 40.345 -6.524 25.180 1.00 16.45 C ATOM 2185 CG1 ILE A 426 41.454 -7.603 25.129 1.00 18.58 C ATOM 2186 CG2 ILE A 426 40.032 -5.968 23.780 1.00 15.71 C ATOM 2187 CD1 ILE A 426 41.101 -8.834 24.295 1.00 19.38 C ATOM 2188 N ALA A 427 39.703 -3.144 25.759 1.00 13.35 N ATOM 2189 CA ALA A 427 38.664 -2.121 25.898 1.00 15.16 C ATOM 2190 C ALA A 427 37.700 -2.189 24.702 1.00 17.19 C ATOM 2191 O ALA A 427 38.145 -2.051 23.552 1.00 16.14 O ATOM 2192 CB ALA A 427 39.303 -0.748 25.973 1.00 16.29 C ATOM 2193 N THR A 428 36.384 -2.390 24.972 1.00 14.37 N ATOM 2194 CA THR A 428 35.362 -2.506 23.933 1.00 14.01 C ATOM 2195 C THR A 428 34.232 -1.490 24.110 1.00 14.56 C ATOM 2196 O THR A 428 34.061 -0.904 25.194 1.00 13.38 O ATOM 2197 CB THR A 428 34.786 -3.953 23.898 1.00 16.20 C ATOM 2198 OG1 THR A 428 34.094 -4.164 22.652 1.00 17.43 O ATOM 2199 CG2 THR A 428 33.880 -4.254 25.101 1.00 14.24 C ATOM 2200 N THR A 429 33.457 -1.278 23.039 1.00 13.65 N ATOM 2201 CA THR A 429 32.268 -0.433 23.133 1.00 13.16 C ATOM 2202 C THR A 429 31.138 -1.130 22.394 1.00 13.27 C ATOM 2203 O THR A 429 31.386 -1.977 21.521 1.00 12.00 O ATOM 2204 CB THR A 429 32.456 0.982 22.526 1.00 16.04 C ATOM 2205 OG1 THR A 429 32.280 0.874 21.094 1.00 15.24 O ATOM 2206 CG2 THR A 429 33.793 1.653 22.935 1.00 14.54 C ATOM 2207 N ALA A 430 29.904 -0.715 22.659 1.00 12.34 N ATOM 2208 CA ALA A 430 28.739 -1.329 22.004 1.00 12.54 C ATOM 2209 C ALA A 430 28.806 -1.121 20.483 1.00 13.89 C ATOM 2210 O ALA A 430 28.320 -1.958 19.735 1.00 14.36 O ATOM 2211 CB ALA A 430 27.458 -0.734 22.562 1.00 12.86 C ATOM 2212 N LEU A 431 29.516 -0.058 20.029 1.00 11.47 N ATOM 2213 CA LEU A 431 29.646 0.188 18.573 1.00 12.76 C ATOM 2214 C LEU A 431 30.706 -0.699 17.896 1.00 17.39 C ATOM 2215 O LEU A 431 30.649 -0.955 16.676 1.00 15.34 O ATOM 2216 CB LEU A 431 30.042 1.644 18.347 1.00 13.39 C ATOM 2217 CG LEU A 431 29.006 2.742 18.715 1.00 16.43 C ATOM 2218 CD1 LEU A 431 29.642 4.124 18.584 1.00 16.62 C ATOM 2219 CD2 LEU A 431 27.778 2.682 17.817 1.00 19.44 C ATOM 2220 N SER A 432 31.740 -1.038 18.663 1.00 13.63 N ATOM 2221 CA SER A 432 32.906 -1.759 18.190 1.00 13.55 C ATOM 2222 C SER A 432 32.623 -3.111 17.569 1.00 14.97 C ATOM 2223 O SER A 432 31.645 -3.789 17.911 1.00 13.94 O ATOM 2224 CB SER A 432 33.946 -1.883 19.312 1.00 15.07 C ATOM 2225 OG SER A 432 34.204 -0.632 19.951 1.00 15.34 O ATOM 2226 N HIS A 433 33.483 -3.500 16.640 1.00 13.30 N ATOM 2227 CA HIS A 433 33.396 -4.821 16.026 1.00 12.36 C ATOM 2228 C HIS A 433 33.566 -5.888 17.160 1.00 15.74 C ATOM 2229 O HIS A 433 34.336 -5.661 18.094 1.00 15.14 O ATOM 2230 CB HIS A 433 34.542 -4.981 15.007 1.00 12.91 C ATOM 2231 CG HIS A 433 34.396 -6.198 14.133 1.00 15.87 C ATOM 2232 ND1 HIS A 433 34.907 -7.438 14.521 1.00 17.45 N ATOM 2233 CD2 HIS A 433 33.747 -6.340 12.950 1.00 18.40 C ATOM 2234 CE1 HIS A 433 34.533 -8.293 13.577 1.00 17.52 C ATOM 2235 NE2 HIS A 433 33.845 -7.683 12.598 1.00 18.33 N ATOM 2236 N PRO A 434 32.865 -7.031 17.112 1.00 14.68 N ATOM 2237 CA PRO A 434 32.979 -7.996 18.238 1.00 14.70 C ATOM 2238 C PRO A 434 34.258 -8.855 18.286 1.00 18.02 C ATOM 2239 O PRO A 434 34.458 -9.610 19.263 1.00 17.37 O ATOM 2240 CB PRO A 434 31.704 -8.846 18.093 1.00 16.98 C ATOM 2241 CG PRO A 434 31.440 -8.833 16.615 1.00 19.04 C ATOM 2242 CD PRO A 434 31.790 -7.425 16.175 1.00 16.61 C ATOM 2243 N ILE A 435 35.132 -8.755 17.252 1.00 14.81 N ATOM 2244 CA ILE A 435 36.346 -9.568 17.175 1.00 15.61 C ATOM 2245 C ILE A 435 37.624 -8.792 17.005 1.00 17.06 C ATOM 2246 O ILE A 435 38.595 -9.100 17.687 1.00 17.76 O ATOM 2247 CB ILE A 435 36.208 -10.626 16.033 1.00 18.41 C ATOM 2248 CG1 ILE A 435 34.991 -11.539 16.257 1.00 20.89 C ATOM 2249 CG2 ILE A 435 37.516 -11.452 15.877 1.00 20.92 C ATOM 2250 CD1 ILE A 435 34.609 -12.414 15.037 1.00 24.37 C ATOM 2251 N GLU A 436 37.652 -7.863 16.027 1.00 14.28 N ATOM 2252 CA GLU A 436 38.866 -7.131 15.642 1.00 13.88 C ATOM 2253 C GLU A 436 39.521 -6.433 16.784 1.00 16.40 C ATOM 2254 O GLU A 436 38.838 -5.780 17.578 1.00 16.50 O ATOM 2255 CB GLU A 436 38.576 -6.104 14.558 1.00 15.98 C ATOM 2256 CG GLU A 436 38.210 -6.700 13.213 1.00 16.81 C ATOM 2257 CD GLU A 436 37.800 -5.626 12.229 1.00 25.51 C ATOM 2258 OE1 GLU A 436 37.104 -5.973 11.254 1.00 21.31 O ATOM 2259 OE2 GLU A 436 38.084 -4.431 12.476 1.00 25.96 O ATOM 2260 N VAL A 437 40.830 -6.610 16.892 1.00 15.78 N ATOM 2261 CA VAL A 437 41.648 -5.934 17.904 1.00 16.30 C ATOM 2262 C VAL A 437 42.769 -5.128 17.249 1.00 21.72 C ATOM 2263 O VAL A 437 43.268 -5.482 16.168 1.00 19.84 O ATOM 2264 CB VAL A 437 42.198 -6.866 19.014 1.00 19.28 C ATOM 2265 CG1 VAL A 437 41.052 -7.586 19.750 1.00 18.00 C ATOM 2266 CG2 VAL A 437 43.197 -7.877 18.441 1.00 19.51 C ATOM 2267 N GLU A 438 43.180 -4.073 17.953 1.00 21.42 N ATOM 2268 CA GLU A 438 44.278 -3.160 17.652 1.00 23.17 C ATOM 2269 C GLU A 438 45.207 -3.287 18.860 1.00 30.26 C ATOM 2270 O GLU A 438 44.751 -3.145 20.004 1.00 26.78 O ATOM 2271 CB GLU A 438 43.728 -1.719 17.574 1.00 25.26 C ATOM 2272 CG GLU A 438 44.725 -0.664 17.136 1.00 39.96 C ATOM 2273 CD GLU A 438 44.043 0.537 16.510 1.00 64.98 C ATOM 2274 OE1 GLU A 438 43.736 1.496 17.254 1.00 61.09 O ATOM 2275 OE2 GLU A 438 43.754 0.493 15.290 1.00 54.26 O ATOM 2276 N ASN A 439 46.489 -3.583 18.619 1.00 31.53 N ATOM 2277 CA ASN A 439 47.464 -3.722 19.700 1.00 34.19 C ATOM 2278 C ASN A 439 48.554 -2.631 19.636 1.00 43.59 C ATOM 2279 O ASN A 439 49.748 -2.911 19.711 1.00 45.61 O ATOM 2280 CB ASN A 439 48.022 -5.152 19.723 1.00 36.51 C ATOM 2281 CG ASN A 439 48.914 -5.473 20.892 1.00 60.34 C ATOM 2282 OD1 ASN A 439 48.983 -4.735 21.881 1.00 51.00 O ATOM 2283 ND2 ASN A 439 49.651 -6.570 20.777 1.00 55.39 N ATOM 2284 N ASN A 440 48.129 -1.374 19.521 1.00 42.86 N ATOM 2285 CA ASN A 440 49.055 -0.247 19.454 1.00 43.35 C ATOM 2286 C ASN A 440 48.710 0.750 20.535 1.00 45.89 C ATOM 2287 O ASN A 440 47.978 1.716 20.282 1.00 45.17 O ATOM 2288 CB ASN A 440 49.073 0.400 18.046 1.00 48.03 C ATOM 2289 CG ASN A 440 49.751 -0.417 16.963 1.00 84.05 C ATOM 2290 OD1 ASN A 440 49.289 -0.462 15.818 1.00 81.74 O ATOM 2291 ND2 ASN A 440 50.885 -1.044 17.271 1.00 77.69 N ATOM 2292 N PHE A 441 49.205 0.488 21.767 1.00 41.24 N ATOM 2293 CA PHE A 441 48.944 1.375 22.894 1.00 39.23 C ATOM 2294 C PHE A 441 49.567 2.744 22.596 1.00 45.80 C ATOM 2295 O PHE A 441 50.771 2.814 22.340 1.00 45.48 O ATOM 2296 CB PHE A 441 49.426 0.778 24.240 1.00 38.78 C ATOM 2297 CG PHE A 441 48.796 1.494 25.416 1.00 37.54 C ATOM 2298 CD1 PHE A 441 49.391 2.630 25.962 1.00 37.62 C ATOM 2299 CD2 PHE A 441 47.564 1.086 25.922 1.00 36.90 C ATOM 2300 CE1 PHE A 441 48.776 3.333 27.001 1.00 37.43 C ATOM 2301 CE2 PHE A 441 46.945 1.797 26.956 1.00 38.28 C ATOM 2302 CZ PHE A 441 47.557 2.913 27.491 1.00 36.08 C ATOM 2303 N PRO A 442 48.747 3.820 22.530 1.00 44.89 N ATOM 2304 CA PRO A 442 49.298 5.145 22.180 1.00 51.03 C ATOM 2305 C PRO A 442 50.194 5.788 23.238 1.00 90.71 C ATOM 2306 O PRO A 442 50.069 5.504 24.425 1.00 63.48 O ATOM 2307 CB PRO A 442 48.052 5.984 21.883 1.00 52.05 C ATOM 2308 CG PRO A 442 46.971 5.334 22.662 1.00 54.29 C ATOM 2309 CD PRO A 442 47.283 3.877 22.747 1.00 48.20 C TER 2310 PRO A 442 ATOM 2311 N ALYS B2027 3.904 2.916 15.870 0.50 50.25 N ATOM 2312 N BLYS B2027 3.898 2.642 15.982 0.50 50.24 N ATOM 2313 CA ALYS B2027 4.714 4.095 15.576 0.50 50.01 C ATOM 2314 CA BLYS B2027 4.717 3.778 15.567 0.50 49.97 C ATOM 2315 C ALYS B2027 5.804 4.353 16.619 0.50 52.99 C ATOM 2316 C BLYS B2027 5.860 4.048 16.558 0.50 53.10 C ATOM 2317 O ALYS B2027 6.834 4.946 16.286 0.50 51.88 O ATOM 2318 O BLYS B2027 6.972 4.369 16.132 0.50 52.23 O ATOM 2319 CB ALYS B2027 3.829 5.342 15.398 0.50 52.77 C ATOM 2320 CB BLYS B2027 3.847 5.030 15.364 0.50 52.59 C ATOM 2321 CG ALYS B2027 3.753 5.849 13.956 0.50 66.90 C ATOM 2322 CG BLYS B2027 4.556 6.167 14.622 0.50 64.49 C ATOM 2323 CD ALYS B2027 2.528 5.320 13.208 0.50 75.71 C ATOM 2324 CD BLYS B2027 4.508 7.485 15.395 0.50 71.88 C ATOM 2325 CE ALYS B2027 2.846 4.134 12.328 0.50 86.24 C ATOM 2326 CE BLYS B2027 5.549 7.613 16.483 0.50 80.36 C ATOM 2327 NZ ALYS B2027 1.612 3.489 11.809 0.50 95.31 N ATOM 2328 NZ BLYS B2027 4.922 7.622 17.828 0.50 90.02 N ATOM 2329 N ASP B2028 5.584 3.915 17.874 1.00 48.99 N ATOM 2330 CA ASP B2028 6.560 4.119 18.951 1.00 48.10 C ATOM 2331 C ASP B2028 7.777 3.174 18.865 1.00 48.79 C ATOM 2332 O ASP B2028 8.818 3.477 19.452 1.00 48.35 O ATOM 2333 CB ASP B2028 5.885 4.094 20.342 1.00 50.43 C ATOM 2334 CG ASP B2028 5.121 2.828 20.706 1.00 64.71 C ATOM 2335 OD1 ASP B2028 4.783 2.664 21.903 1.00 66.52 O ATOM 2336 OD2 ASP B2028 4.826 2.018 19.789 1.00 69.55 O ATOM 2337 N ILE B2029 7.662 2.066 18.097 1.00 42.56 N ATOM 2338 CA ILE B2029 8.764 1.119 17.897 1.00 40.97 C ATOM 2339 C ILE B2029 9.476 1.268 16.524 1.00 43.07 C ATOM 2340 O ILE B2029 10.391 0.507 16.214 1.00 41.62 O ATOM 2341 CB ILE B2029 8.403 -0.353 18.273 1.00 43.82 C ATOM 2342 CG1 ILE B2029 7.435 -0.999 17.255 1.00 44.06 C ATOM 2343 CG2 ILE B2029 7.870 -0.444 19.711 1.00 43.69 C ATOM 2344 CD1 ILE B2029 8.004 -2.217 16.582 1.00 47.75 C ATOM 2345 N GLY B2030 9.063 2.246 15.729 1.00 38.97 N ATOM 2346 CA GLY B2030 9.676 2.471 14.424 1.00 38.43 C ATOM 2347 C GLY B2030 8.872 1.990 13.232 1.00 42.90 C ATOM 2348 O GLY B2030 9.416 1.935 12.121 1.00 40.90 O ATOM 2349 N ALA B2031 7.557 1.654 13.437 1.00 40.27 N ATOM 2350 CA ALA B2031 6.646 1.257 12.343 1.00 40.50 C ATOM 2351 C ALA B2031 6.742 2.356 11.287 1.00 42.66 C ATOM 2352 O ALA B2031 6.731 3.540 11.634 1.00 40.95 O ATOM 2353 CB ALA B2031 5.215 1.138 12.856 1.00 41.14 C ATOM 2354 N GLY B2032 6.968 1.956 10.041 1.00 40.44 N ATOM 2355 CA GLY B2032 7.220 2.888 8.949 1.00 40.73 C ATOM 2356 C GLY B2032 6.112 3.099 7.936 1.00 46.55 C ATOM 2357 O GLY B2032 5.051 2.470 8.028 1.00 45.56 O ATOM 2358 N PRO B2033 6.351 3.995 6.942 1.00 44.01 N ATOM 2359 CA PRO B2033 5.309 4.267 5.939 1.00 44.34 C ATOM 2360 C PRO B2033 5.129 3.144 4.925 1.00 49.11 C ATOM 2361 O PRO B2033 6.046 2.362 4.696 1.00 47.71 O ATOM 2362 CB PRO B2033 5.802 5.550 5.258 1.00 45.97 C ATOM 2363 CG PRO B2033 7.292 5.486 5.376 1.00 50.01 C ATOM 2364 CD PRO B2033 7.559 4.821 6.704 1.00 45.62 C ATOM 2365 N VAL B2034 3.934 3.062 4.336 1.00 47.77 N ATOM 2366 CA VAL B2034 3.636 2.098 3.284 1.00 48.50 C ATOM 2367 C VAL B2034 4.014 2.800 1.968 1.00 52.60 C ATOM 2368 O VAL B2034 3.451 3.851 1.639 1.00 52.61 O ATOM 2369 CB VAL B2034 2.184 1.520 3.339 1.00 53.12 C ATOM 2370 CG1 VAL B2034 1.135 2.597 3.625 1.00 53.19 C ATOM 2371 CG2 VAL B2034 1.838 0.719 2.086 1.00 53.00 C ATOM 2372 N ALA B2035 5.051 2.284 1.294 1.00 48.39 N ATOM 2373 CA ALA B2035 5.560 2.878 0.062 1.00 48.17 C ATOM 2374 C ALA B2035 5.710 1.854 -1.048 1.00 52.29 C ATOM 2375 O ALA B2035 6.194 0.744 -0.810 1.00 51.82 O ATOM 2376 CB ALA B2035 6.886 3.567 0.323 1.00 48.88 C ATOM 2377 N SER B2036 5.286 2.236 -2.262 1.00 48.85 N ATOM 2378 CA SER B2036 5.351 1.398 -3.460 1.00 48.98 C ATOM 2379 C SER B2036 6.349 1.968 -4.479 1.00 50.88 C ATOM 2380 O SER B2036 6.979 1.202 -5.199 1.00 49.99 O ATOM 2381 CB SER B2036 3.968 1.265 -4.092 1.00 54.10 C ATOM 2382 OG SER B2036 3.954 0.223 -5.055 1.00 66.66 O ATOM 2383 N CYS B2037 6.471 3.307 -4.546 1.00 46.68 N ATOM 2384 CA CYS B2037 7.396 4.003 -5.447 1.00 46.24 C ATOM 2385 C CYS B2037 8.230 5.021 -4.686 1.00 45.50 C ATOM 2386 O CYS B2037 7.748 5.633 -3.732 1.00 45.50 O ATOM 2387 CB CYS B2037 6.662 4.640 -6.624 1.00 47.51 C ATOM 2388 SG CYS B2037 5.933 3.442 -7.775 1.00 52.07 S ATOM 2389 N PHE B2038 9.488 5.191 -5.111 1.00 37.18 N ATOM 2390 CA PHE B2038 10.443 6.103 -4.485 1.00 34.26 C ATOM 2391 C PHE B2038 10.994 7.048 -5.519 1.00 36.95 C ATOM 2392 O PHE B2038 11.195 6.652 -6.664 1.00 36.84 O ATOM 2393 CB PHE B2038 11.602 5.304 -3.840 1.00 34.57 C ATOM 2394 CG PHE B2038 11.143 4.182 -2.943 1.00 34.90 C ATOM 2395 CD1 PHE B2038 11.000 2.889 -3.436 1.00 37.47 C ATOM 2396 CD2 PHE B2038 10.841 4.417 -1.605 1.00 35.51 C ATOM 2397 CE1 PHE B2038 10.528 1.856 -2.614 1.00 38.32 C ATOM 2398 CE2 PHE B2038 10.386 3.381 -0.779 1.00 37.60 C ATOM 2399 CZ PHE B2038 10.229 2.108 -1.287 1.00 35.81 C ATOM 2400 N THR B2039 11.224 8.301 -5.119 1.00 32.54 N ATOM 2401 CA THR B2039 11.812 9.344 -5.949 1.00 32.21 C ATOM 2402 C THR B2039 13.206 9.636 -5.375 1.00 34.60 C ATOM 2403 O THR B2039 13.333 9.932 -4.179 1.00 34.17 O ATOM 2404 CB THR B2039 10.895 10.573 -5.983 1.00 45.04 C ATOM 2405 OG1 THR B2039 9.603 10.156 -6.434 1.00 50.48 O ATOM 2406 CG2 THR B2039 11.429 11.685 -6.890 1.00 44.23 C ATOM 2407 N THR B2040 14.249 9.504 -6.207 1.00 29.76 N ATOM 2408 CA THR B2040 15.618 9.779 -5.762 1.00 27.98 C ATOM 2409 C THR B2040 15.776 11.235 -5.415 1.00 31.87 C ATOM 2410 O THR B2040 15.271 12.113 -6.129 1.00 32.90 O ATOM 2411 CB THR B2040 16.663 9.307 -6.782 1.00 30.89 C ATOM 2412 OG1 THR B2040 16.502 10.019 -8.009 1.00 30.84 O ATOM 2413 CG2 THR B2040 16.619 7.810 -7.015 1.00 26.15 C ATOM 2414 N ARG B2041 16.474 11.502 -4.319 1.00 26.67 N ATOM 2415 CA ARG B2041 16.719 12.853 -3.832 1.00 26.73 C ATOM 2416 C ARG B2041 17.855 13.523 -4.602 1.00 35.52 C ATOM 2417 O ARG B2041 17.781 14.722 -4.885 1.00 36.24 O ATOM 2418 CB ARG B2041 17.035 12.838 -2.334 1.00 25.77 C ATOM 2419 CG ARG B2041 15.849 12.411 -1.465 1.00 30.72 C ATOM 2420 CD ARG B2041 16.219 12.412 0.009 1.00 29.22 C ATOM 2421 NE ARG B2041 15.029 12.452 0.855 1.00 24.90 N ATOM 2422 CZ ARG B2041 14.470 11.396 1.439 1.00 33.31 C ATOM 2423 NH1 ARG B2041 15.002 10.186 1.294 1.00 21.21 N ATOM 2424 NH2 ARG B2041 13.378 11.541 2.177 1.00 27.24 N ATOM 2425 N MET B2042 18.915 12.768 -4.919 1.00 34.69 N ATOM 2426 CA MET B2042 20.061 13.335 -5.646 1.00 36.16 C ATOM 2427 C MET B2042 19.815 13.357 -7.143 1.00 44.30 C ATOM 2428 O MET B2042 19.194 12.439 -7.682 1.00 42.62 O ATOM 2429 CB MET B2042 21.368 12.617 -5.292 1.00 38.18 C ATOM 2430 CG MET B2042 21.678 12.690 -3.811 1.00 41.40 C ATOM 2431 SD MET B2042 23.170 11.810 -3.295 1.00 45.33 S ATOM 2432 CE MET B2042 22.676 10.135 -3.553 1.00 41.63 C ATOM 2433 N SER B2043 20.278 14.433 -7.805 1.00 46.44 N ATOM 2434 CA SER B2043 20.117 14.643 -9.248 1.00 48.30 C ATOM 2435 C SER B2043 20.904 13.603 -10.066 1.00 54.89 C ATOM 2436 O SER B2043 22.016 13.249 -9.665 1.00 53.82 O ATOM 2437 CB SER B2043 20.525 16.062 -9.638 1.00 53.87 C ATOM 2438 OG SER B2043 21.870 16.327 -9.273 1.00 67.70 O ATOM 2439 N PRO B2044 20.347 13.077 -11.187 1.00 54.10 N ATOM 2440 CA PRO B2044 19.028 13.396 -11.776 1.00 54.19 C ATOM 2441 C PRO B2044 17.869 12.715 -11.043 1.00 57.54 C ATOM 2442 O PRO B2044 18.002 11.541 -10.687 1.00 57.37 O ATOM 2443 CB PRO B2044 19.180 12.932 -13.231 1.00 56.03 C ATOM 2444 CG PRO B2044 20.143 11.772 -13.156 1.00 60.69 C ATOM 2445 CD PRO B2044 21.072 12.069 -11.992 1.00 56.18 C ATOM 2446 N PRO B2045 16.742 13.417 -10.772 1.00 53.51 N ATOM 2447 CA PRO B2045 15.623 12.745 -10.090 1.00 52.48 C ATOM 2448 C PRO B2045 15.003 11.670 -10.980 1.00 52.77 C ATOM 2449 O PRO B2045 14.854 11.870 -12.190 1.00 51.87 O ATOM 2450 CB PRO B2045 14.651 13.884 -9.769 1.00 54.56 C ATOM 2451 CG PRO B2045 14.940 14.927 -10.780 1.00 59.67 C ATOM 2452 CD PRO B2045 16.405 14.813 -11.121 1.00 55.53 C ATOM 2453 N GLN B2046 14.736 10.499 -10.390 1.00 46.17 N ATOM 2454 CA GLN B2046 14.142 9.366 -11.088 1.00 44.75 C ATOM 2455 C GLN B2046 13.184 8.623 -10.172 1.00 46.99 C ATOM 2456 O GLN B2046 13.311 8.696 -8.942 1.00 45.96 O ATOM 2457 CB GLN B2046 15.210 8.442 -11.719 1.00 45.83 C ATOM 2458 CG GLN B2046 15.958 7.537 -10.747 1.00 56.13 C ATOM 2459 CD GLN B2046 16.936 6.623 -11.442 1.00 66.60 C ATOM 2460 OE1 GLN B2046 16.561 5.672 -12.133 1.00 59.00 O ATOM 2461 NE2 GLN B2046 18.215 6.858 -11.225 1.00 56.93 N ATOM 2462 N GLN B2047 12.207 7.938 -10.774 1.00 42.58 N ATOM 2463 CA GLN B2047 11.198 7.184 -10.051 1.00 42.16 C ATOM 2464 C GLN B2047 11.579 5.713 -10.044 1.00 45.23 C ATOM 2465 O GLN B2047 11.804 5.116 -11.099 1.00 45.13 O ATOM 2466 CB GLN B2047 9.812 7.404 -10.684 1.00 44.07 C ATOM 2467 CG GLN B2047 8.637 7.158 -9.728 1.00 62.97 C ATOM 2468 CD GLN B2047 7.287 7.215 -10.413 1.00 85.72 C ATOM 2469 OE1 GLN B2047 6.455 6.313 -10.270 1.00 79.75 O ATOM 2470 NE2 GLN B2047 7.023 8.283 -11.158 1.00 82.62 N ATOM 2471 N ILE B2048 11.707 5.140 -8.842 1.00 40.08 N ATOM 2472 CA ILE B2048 12.054 3.735 -8.666 1.00 38.83 C ATOM 2473 C ILE B2048 10.859 3.081 -7.993 1.00 43.36 C ATOM 2474 O ILE B2048 10.463 3.505 -6.908 1.00 41.84 O ATOM 2475 CB ILE B2048 13.406 3.565 -7.896 1.00 41.42 C ATOM 2476 CG1 ILE B2048 14.585 4.122 -8.737 1.00 41.31 C ATOM 2477 CG2 ILE B2048 13.647 2.100 -7.519 1.00 41.23 C ATOM 2478 CD1 ILE B2048 15.936 4.301 -7.980 1.00 47.15 C ATOM 2479 N CYS B2049 10.254 2.097 -8.658 1.00 42.57 N ATOM 2480 CA CYS B2049 9.064 1.406 -8.154 1.00 44.64 C ATOM 2481 C CYS B2049 9.338 -0.054 -7.819 1.00 47.20 C ATOM 2482 O CYS B2049 10.193 -0.684 -8.446 1.00 44.29 O ATOM 2483 CB CYS B2049 7.897 1.546 -9.133 1.00 46.70 C ATOM 2484 SG CYS B2049 7.268 3.238 -9.309 1.00 51.66 S ATOM 2485 N LEU B2050 8.573 -0.602 -6.852 1.00 45.87 N ATOM 2486 CA LEU B2050 8.672 -2.006 -6.443 1.00 46.71 C ATOM 2487 C LEU B2050 8.199 -2.953 -7.564 1.00 52.33 C ATOM 2488 O LEU B2050 7.439 -2.531 -8.442 1.00 53.21 O ATOM 2489 CB LEU B2050 7.915 -2.275 -5.118 1.00 46.89 C ATOM 2490 CG LEU B2050 8.290 -1.412 -3.885 1.00 51.82 C ATOM 2491 CD1 LEU B2050 7.433 -1.759 -2.685 1.00 52.28 C ATOM 2492 CD2 LEU B2050 9.753 -1.535 -3.524 1.00 54.05 C ATOM 2493 N ASN B2051 8.680 -4.224 -7.532 1.00 48.68 N ATOM 2494 CA ASN B2051 8.441 -5.363 -8.446 1.00 72.76 C ATOM 2495 C ASN B2051 9.519 -5.548 -9.519 1.00 91.44 C ATOM 2496 O ASN B2051 10.319 -4.650 -9.769 1.00 56.49 O ATOM 2497 CB ASN B2051 7.020 -5.414 -9.053 1.00 72.86 C ATOM 2498 CG ASN B2051 5.878 -5.298 -8.064 1.00 92.87 C ATOM 2499 OD1 ASN B2051 5.888 -5.876 -6.967 1.00 85.96 O ATOM 2500 ND2 ASN B2051 4.855 -4.547 -8.446 1.00 84.66 N TER 2501 ASN B2051 HETATM 2502 O HOH A 1 18.596 11.254 19.256 1.00 22.56 O HETATM 2503 O HOH A 2 24.404 3.479 12.457 1.00 17.52 O HETATM 2504 O HOH A 3 29.508 10.350 30.464 1.00 18.92 O HETATM 2505 O HOH A 4 27.182 3.696 36.835 1.00 16.46 O HETATM 2506 O HOH A 5 38.028 1.755 18.271 1.00 19.15 O HETATM 2507 O HOH A 6 21.995 0.957 15.877 1.00 21.64 O HETATM 2508 O HOH A 7 22.922 11.191 16.179 1.00 19.63 O HETATM 2509 O HOH A 8 39.745 -16.876 35.582 1.00 40.15 O HETATM 2510 O HOH A 9 31.437 3.103 15.230 1.00 17.39 O HETATM 2511 O HOH A 10 29.498 9.552 25.841 1.00 15.64 O HETATM 2512 O HOH A 11 38.780 -8.895 37.102 1.00 38.03 O HETATM 2513 O HOH A 12 34.954 -11.554 42.238 1.00 19.56 O HETATM 2514 O HOH A 13 39.119 1.181 34.784 1.00 19.43 O HETATM 2515 O HOH A 14 19.894 -1.547 26.410 1.00 24.89 O HETATM 2516 O HOH A 15 27.433 15.279 24.213 1.00 45.36 O HETATM 2517 O HOH A 16 39.358 9.773 18.680 1.00 22.56 O HETATM 2518 O HOH A 17 37.708 0.509 9.041 1.00 24.63 O HETATM 2519 O HOH A 18 30.998 -5.921 11.158 1.00 17.17 O HETATM 2520 O HOH A 19 44.095 -9.237 36.168 1.00 44.76 O HETATM 2521 O HOH A 20 31.426 -4.686 -5.151 1.00 21.93 O HETATM 2522 O HOH A 21 32.761 -1.568 40.751 1.00 20.78 O HETATM 2523 O HOH A 22 35.256 -17.708 34.306 1.00 19.05 O HETATM 2524 O HOH A 23 27.980 -11.695 9.122 1.00 19.28 O HETATM 2525 O HOH A 24 38.247 3.942 14.495 1.00 44.23 O HETATM 2526 O HOH A 25 18.176 -7.833 0.811 1.00 20.15 O HETATM 2527 O HOH A 27 36.611 -0.489 21.250 1.00 22.05 O HETATM 2528 O HOH A 28 31.916 0.344 -10.184 1.00 27.46 O HETATM 2529 O HOH A 29 21.969 9.150 4.292 1.00 18.91 O HETATM 2530 O HOH A 30 37.274 -0.184 37.317 1.00 29.41 O HETATM 2531 O HOH A 31 39.254 1.437 15.441 1.00 29.73 O HETATM 2532 O HOH A 32 15.203 -3.251 -4.210 1.00 26.33 O HETATM 2533 O HOH A 33 38.719 -13.255 23.467 1.00 24.58 O HETATM 2534 O HOH A 34 41.209 4.131 19.385 1.00 27.13 O HETATM 2535 O HOH A 35 39.703 -14.410 26.056 1.00 47.68 O HETATM 2536 O HOH A 36 19.400 3.202 27.257 1.00 27.12 O HETATM 2537 O HOH A 37 28.012 -9.740 15.527 1.00 18.16 O HETATM 2538 O HOH A 38 25.738 13.915 19.291 1.00 32.92 O HETATM 2539 O HOH A 39 44.525 11.058 40.356 1.00 45.07 O HETATM 2540 O HOH A 40 24.018 12.127 6.126 1.00 34.87 O HETATM 2541 O HOH A 41 29.029 2.050 35.675 1.00 15.87 O HETATM 2542 O HOH A 42 16.985 -5.547 -0.408 1.00 20.79 O HETATM 2543 O HOH A 43 24.829 -9.821 1.735 1.00 22.36 O HETATM 2544 O HOH A 44 29.411 13.388 7.234 1.00 29.85 O HETATM 2545 O HOH A 45 33.786 13.326 20.819 1.00 24.12 O HETATM 2546 O HOH A 46 35.598 10.149 25.685 1.00 21.10 O HETATM 2547 O HOH A 47 35.936 -19.411 32.271 1.00 26.07 O HETATM 2548 O HOH A 48 41.342 6.883 19.094 1.00 30.69 O HETATM 2549 O HOH A 49 20.231 11.451 16.970 1.00 20.14 O HETATM 2550 O HOH A 50 48.051 -7.121 34.232 1.00 59.80 O HETATM 2551 O HOH A 51 21.780 1.789 28.425 1.00 22.69 O HETATM 2552 O HOH A 52 29.669 8.642 -16.926 1.00 24.55 O HETATM 2553 O HOH A 53 33.987 8.558 2.809 1.00 36.17 O HETATM 2554 O HOH A 54 44.831 -5.863 36.434 1.00 45.24 O HETATM 2555 O HOH A 55 30.335 12.719 14.479 1.00 40.60 O HETATM 2556 O HOH A 56 11.993 9.224 17.557 1.00 25.85 O HETATM 2557 O HOH A 57 34.217 14.869 18.806 1.00 36.54 O HETATM 2558 O HOH A 58 15.586 -2.249 11.095 1.00 21.44 O HETATM 2559 O HOH A 59 35.343 7.075 7.057 1.00 22.77 O HETATM 2560 O HOH A 60 17.881 6.150 9.190 1.00 18.82 O HETATM 2561 O HOH A 61 39.725 12.503 27.367 1.00 42.52 O HETATM 2562 O HOH A 62 38.742 -11.227 19.393 1.00 19.68 O HETATM 2563 O HOH A 63 21.422 -4.248 -7.517 1.00 47.03 O HETATM 2564 O HOH A 64 50.088 -5.208 32.523 1.00 30.34 O HETATM 2565 O HOH A 65 15.223 -6.707 -3.172 1.00 30.35 O HETATM 2566 O HOH A 66 27.286 -15.693 18.723 1.00 37.57 O HETATM 2567 O HOH A 67 18.061 -9.755 -0.965 1.00 31.29 O HETATM 2568 O HOH A 68 36.097 12.777 26.140 1.00 30.85 O HETATM 2569 O HOH A 69 28.265 -11.967 6.454 1.00 23.73 O HETATM 2570 O HOH A 70 47.878 5.649 31.152 1.00 30.33 O HETATM 2571 O HOH A 71 24.558 -12.034 -0.196 1.00 54.39 O HETATM 2572 O HOH A 72 19.992 13.674 15.477 1.00 28.18 O HETATM 2573 O HOH A 73 25.423 13.181 10.141 1.00 26.63 O HETATM 2574 O HOH A 74 38.273 12.706 33.386 1.00 35.63 O HETATM 2575 O HOH A 75 21.597 -12.671 21.476 1.00 45.32 O HETATM 2576 O HOH A 76 23.662 -8.858 21.652 1.00 32.85 O HETATM 2577 O HOH A 77 9.972 4.439 10.768 1.00 24.60 O HETATM 2578 O HOH A 78 32.623 -13.387 -1.030 1.00 45.09 O HETATM 2579 O HOH A 79 13.714 4.408 25.874 1.00 47.04 O HETATM 2580 O HOH A 80 23.855 14.316 12.287 1.00 37.56 O HETATM 2581 O HOH A 81 46.396 4.725 39.389 1.00 63.54 O HETATM 2582 O HOH A 82 36.135 -7.449 41.201 1.00 31.66 O HETATM 2583 O HOH A 83 29.293 13.336 26.508 1.00 47.99 O HETATM 2584 O HOH A 84 34.076 14.793 23.122 1.00 30.34 O HETATM 2585 O HOH A 85 23.270 -13.837 19.821 1.00 46.93 O HETATM 2586 O HOH A 86 37.504 0.668 40.875 1.00 47.73 O HETATM 2587 O HOH A 87 15.444 7.007 2.184 1.00 20.31 O HETATM 2588 O HOH A 88 24.857 0.076 -10.992 1.00 35.36 O HETATM 2589 O HOH A 89 32.087 5.449 -10.074 1.00 22.63 O HETATM 2590 O HOH A 90 31.192 -0.852 42.822 1.00 44.78 O HETATM 2591 O HOH A 91 16.128 14.091 17.642 1.00 42.32 O HETATM 2592 O HOH A 92 33.939 -21.806 28.813 1.00 41.97 O HETATM 2593 O HOH A 93 37.639 13.715 24.106 1.00 37.04 O HETATM 2594 O HOH A 94 27.676 -8.378 39.003 1.00 18.39 O HETATM 2595 O HOH A 476 21.492 10.411 0.154 1.00 24.08 O HETATM 2596 O HOH A 477 22.756 3.267 14.757 1.00 22.68 O HETATM 2597 O HOH A 478 18.390 8.988 20.774 1.00 17.90 O HETATM 2598 O HOH A 479 45.183 12.361 22.553 1.00 29.31 O HETATM 2599 O HOH A 480 17.327 -12.452 11.122 1.00 32.00 O HETATM 2600 O HOH A 481 27.824 9.509 28.116 1.00 21.99 O HETATM 2601 O HOH A 482 32.767 -4.304 40.541 1.00 41.38 O HETATM 2602 O HOH A 483 26.802 -4.018 39.793 1.00 35.22 O HETATM 2603 O HOH A 484 24.608 -4.765 -7.524 1.00 25.81 O HETATM 2604 O HOH A 485 39.003 4.925 40.635 1.00 26.33 O HETATM 2605 O HOH A 486 42.890 3.890 39.838 1.00 36.39 O HETATM 2606 O HOH A 487 32.309 1.156 43.416 1.00 39.50 O HETATM 2607 O HOH A 488 19.232 -9.522 21.839 1.00 45.29 O HETATM 2608 O HOH A 489 38.812 2.592 42.165 1.00 60.87 O HETATM 2609 O HOH A 490 36.895 -1.339 34.655 1.00 23.63 O HETATM 2610 O HOH A 491 22.108 13.770 19.973 1.00 39.91 O HETATM 2611 O HOH A 492 19.362 15.503 11.432 1.00 43.00 O HETATM 2612 O HOH A 493 25.486 -14.642 8.148 1.00 41.16 O HETATM 2613 O HOH A 494 25.341 4.579 -13.970 1.00 37.25 O HETATM 2614 O HOH A 495 49.084 3.070 31.561 1.00 31.05 O HETATM 2615 O HOH A 496 32.052 13.999 11.718 1.00 39.33 O HETATM 2616 O HOH A 497 30.652 15.701 25.117 1.00 54.10 O HETATM 2617 O HOH A 498 8.277 -9.001 5.977 1.00 35.03 O HETATM 2618 O HOH A 499 14.560 13.444 10.647 1.00 41.19 O HETATM 2619 O HOH A 500 36.043 -11.849 19.815 1.00 23.34 O HETATM 2620 O HOH A 501 32.734 -5.612 9.152 1.00 31.26 O HETATM 2621 O HOH A 502 29.096 -14.660 9.691 1.00 42.27 O HETATM 2622 O HOH A 503 35.494 -14.482 18.586 1.00 32.85 O HETATM 2623 O HOH A 504 19.750 5.588 28.393 1.00 37.16 O HETATM 2624 O HOH A 505 16.617 13.084 7.415 1.00 38.80 O HETATM 2625 O HOH A 506 34.177 15.154 7.223 1.00 33.01 O HETATM 2626 O HOH A 507 34.582 15.376 12.531 1.00 43.33 O HETATM 2627 O HOH A 508 26.865 -14.153 5.845 1.00 41.06 O HETATM 2628 O HOH A 509 22.529 -11.641 2.094 1.00 65.36 O HETATM 2629 O HOH A 510 29.015 -6.080 39.624 1.00 21.56 O HETATM 2630 O HOH A 511 21.347 11.271 2.716 1.00 24.21 O HETATM 2631 O HOH A 512 33.873 -8.158 9.717 1.00 29.09 O HETATM 2632 O HOH A 513 31.183 -6.100 41.694 1.00 29.87 O HETATM 2633 O HOH A 514 25.577 8.914 -11.703 1.00 25.08 O HETATM 2634 O HOH A 515 35.058 13.871 16.627 1.00 34.41 O HETATM 2635 O HOH A 516 36.045 11.361 17.515 1.00 23.41 O HETATM 2636 O HOH A 517 13.975 14.665 14.718 1.00 41.82 O HETATM 2637 O HOH A 518 2.552 8.454 5.644 1.00 46.53 O HETATM 2638 O HOH A 519 19.761 -12.289 6.829 1.00 38.53 O HETATM 2639 O HOH A 520 8.757 -5.993 -5.043 1.00 45.69 O HETATM 2640 O HOH A 521 28.977 -5.883 -8.886 1.00 28.47 O HETATM 2641 O HOH A 522 33.835 5.610 -7.990 1.00 26.43 O HETATM 2642 O HOH A 523 33.347 6.086 -12.409 1.00 28.59 O HETATM 2643 O HOH A 524 33.160 8.908 -12.742 1.00 21.69 O HETATM 2644 O HOH A 525 31.324 2.358 -13.595 1.00 32.60 O HETATM 2645 O HOH A 526 32.647 4.227 -16.863 1.00 50.67 O HETATM 2646 O HOH A 527 30.859 5.479 -18.353 1.00 32.15 O HETATM 2647 O HOH A 528 27.992 7.558 -18.843 1.00 30.11 O HETATM 2648 O HOH A 529 25.737 8.402 -17.540 1.00 27.74 O HETATM 2649 O HOH A 530 28.698 2.171 -16.503 1.00 42.56 O HETATM 2650 O HOH A 531 37.435 -14.932 14.256 1.00 29.69 O HETATM 2651 O HOH A 532 32.505 11.009 -3.652 1.00 21.93 O HETATM 2652 O HOH A 533 19.787 6.617 4.803 1.00 31.56 O HETATM 2653 O HOH A 534 20.442 9.588 -7.664 1.00 31.23 O HETATM 2654 O HOH A 535 22.376 8.561 -9.605 1.00 45.54 O HETATM 2655 O HOH A 536 22.473 5.975 -12.469 1.00 40.99 O HETATM 2656 O HOH A 537 34.500 -9.292 0.264 1.00 42.77 O HETATM 2657 O HOH A 538 10.301 1.642 7.966 1.00 36.67 O HETATM 2658 O HOH A 539 22.916 13.576 14.906 1.00 41.95 O HETATM 2659 O HOH A 540 40.320 1.063 12.919 1.00 42.32 O HETATM 2660 O HOH A 541 38.226 2.125 11.425 1.00 31.93 O HETATM 2661 O HOH A 542 44.076 -4.190 13.925 1.00 30.90 O HETATM 2662 O HOH A 543 49.003 -9.398 25.843 1.00 51.08 O HETATM 2663 O HOH A 544 40.293 -11.371 21.872 1.00 26.67 O HETATM 2664 O HOH A 545 15.200 11.874 26.148 1.00 43.08 O HETATM 2665 O HOH A 546 23.420 13.252 24.633 1.00 33.62 O HETATM 2666 O HOH A 547 25.927 15.024 28.281 1.00 48.74 O HETATM 2667 O HOH A 548 20.650 14.618 25.952 1.00 49.85 O HETATM 2668 O HOH A 549 51.124 -2.966 25.549 1.00 37.54 O HETATM 2669 O HOH A 550 34.696 -12.604 9.206 1.00 44.03 O HETATM 2670 O HOH A 551 34.208 -10.373 11.241 1.00 33.70 O HETATM 2671 O HOH A 552 15.925 -1.899 24.230 1.00 40.21 O HETATM 2672 O HOH A 553 7.452 10.346 15.770 1.00 61.13 O HETATM 2673 O HOH A 554 33.999 -4.335 -4.331 1.00 27.15 O HETATM 2674 O HOH A 555 35.501 0.465 -4.451 1.00 41.16 O HETATM 2675 O HOH A 556 36.136 1.052 -1.514 1.00 37.60 O HETATM 2676 O HOH A 557 36.055 4.755 -5.097 1.00 35.40 O HETATM 2677 O HOH A 558 34.993 12.396 -6.319 1.00 41.02 O HETATM 2678 O HOH A 559 27.196 16.296 -9.221 1.00 44.55 O HETATM 2679 O HOH A 560 24.544 14.728 -4.405 1.00 43.48 O HETATM 2680 O HOH A 561 35.530 1.959 1.484 1.00 36.87 O HETATM 2681 O HOH A 562 28.619 13.752 -0.199 1.00 32.35 O HETATM 2682 O HOH A 563 24.464 12.550 -0.507 1.00 37.28 O HETATM 2683 O HOH A 564 8.188 9.147 -3.887 1.00 45.39 O HETATM 2684 O HOH A 565 14.377 15.210 0.911 1.00 42.37 O HETATM 2685 O HOH A 566 27.240 -12.863 2.897 1.00 51.78 O HETATM 2686 O HOH A 567 35.817 12.290 4.900 1.00 32.10 O HETATM 2687 O HOH A 568 38.027 8.989 7.679 1.00 41.89 O HETATM 2688 O HOH A 569 29.175 -3.678 40.868 1.00 41.54 O HETATM 2689 O HOH A 570 30.085 -15.802 27.638 1.00 24.81 O HETATM 2690 O HOH A 571 20.876 -1.466 30.262 1.00 35.10 O HETATM 2691 O HOH A 572 20.840 2.875 30.751 1.00 41.78 O HETATM 2692 O HOH A 573 17.629 1.267 28.276 1.00 46.39 O HETATM 2693 O HOH A 574 43.779 -12.171 23.993 1.00 43.12 O HETATM 2694 O HOH A 575 42.963 -10.808 21.474 1.00 39.78 O HETATM 2695 O HOH A 576 37.130 -20.146 30.018 1.00 47.64 O HETATM 2696 O HOH A 577 23.670 10.815 -14.041 1.00 39.22 O HETATM 2697 O HOH A 578 16.224 16.573 -1.056 1.00 58.85 O HETATM 2698 O HOH A 579 4.560 15.894 5.467 1.00 52.52 O HETATM 2699 O HOH A 580 6.915 15.465 4.004 1.00 53.99 O HETATM 2700 O HOH A 581 2.946 14.162 0.979 1.00 53.71 O HETATM 2701 O HOH A 582 1.723 11.978 13.452 1.00 58.29 O HETATM 2702 O HOH A 583 16.055 -9.221 -3.550 1.00 47.49 O HETATM 2703 O HOH A 584 35.507 -2.188 -5.006 1.00 47.46 O HETATM 2704 O HOH A 585 29.052 19.253 -10.464 1.00 44.76 O HETATM 2705 O HOH A 586 28.927 20.938 -8.408 1.00 56.40 O HETATM 2706 O HOH A 587 33.023 20.335 -6.349 1.00 52.10 O HETATM 2707 O HOH A 588 34.305 11.281 2.526 1.00 35.11 O HETATM 2708 O HOH A 589 20.996 4.812 5.778 1.00 34.04 O HETATM 2709 O HOH A 590 33.495 -2.081 7.162 1.00 36.01 O HETATM 2710 O HOH A 591 35.583 -0.408 4.985 1.00 55.58 O HETATM 2711 O HOH A 592 36.377 5.534 -1.084 1.00 36.11 O HETATM 2712 O HOH A 593 33.979 11.632 -1.605 1.00 40.45 O HETATM 2713 O HOH A 594 29.977 13.811 2.453 1.00 42.25 O HETATM 2714 O HOH A 595 34.423 -5.806 2.739 1.00 40.61 O HETATM 2715 O HOH A 596 24.690 -18.058 14.804 1.00 38.27 O HETATM 2716 O HOH A 597 24.795 -16.617 18.847 1.00 69.73 O HETATM 2717 O HOH A 598 46.698 -8.511 18.411 1.00 36.64 O HETATM 2718 O HOH A 599 39.927 -0.210 40.970 1.00 46.27 O HETATM 2719 O HOH A 600 26.122 -6.886 37.066 1.00 36.70 O HETATM 2720 O HOH A 601 18.661 11.157 27.497 1.00 63.27 O HETATM 2721 O HOH A 602 42.607 -16.335 29.778 1.00 42.45 O HETATM 2722 O HOH A 603 22.747 4.896 31.866 1.00 27.93 O HETATM 2723 O HOH A 604 22.443 7.719 31.485 1.00 30.53 O HETATM 2724 O HOH A 605 37.226 -6.980 38.123 1.00 50.49 O HETATM 2725 O HOH A 606 37.786 14.228 27.902 1.00 65.57 O HETATM 2726 O HOH A 607 36.257 15.362 29.816 1.00 39.41 O HETATM 2727 O HOH A 608 39.144 14.607 31.573 1.00 50.80 O HETATM 2728 O HOH A 609 43.943 -2.857 36.444 1.00 52.93 O HETATM 2729 O HOH A 610 44.612 -1.516 13.732 1.00 51.33 O HETATM 2730 O HOH A 611 45.246 3.296 18.530 1.00 60.63 O HETATM 2731 O HOH A 612 41.029 2.380 17.266 1.00 55.63 O HETATM 2732 O HOH A 613 47.478 -4.115 16.116 1.00 43.25 O HETATM 2733 O HOH A 614 46.043 -6.128 15.431 1.00 61.80 O HETATM 2734 O HOH A 615 49.444 -2.494 23.046 1.00 67.23 O HETATM 2735 O HOH A 616 21.978 15.971 11.188 1.00 51.70 O HETATM 2736 O HOH A 617 27.517 -16.601 8.841 1.00 48.25 O HETATM 2737 O HOH A 618 23.989 -12.122 4.270 1.00 48.19 O HETATM 2738 O HOH A 619 33.211 -15.889 0.451 1.00 86.15 O HETATM 2739 O HOH A 620 38.149 13.559 9.983 1.00 36.77 O HETATM 2740 O HOH A 621 39.454 12.626 8.013 1.00 39.52 O HETATM 2741 O HOH A 622 15.308 2.434 26.700 1.00 48.45 O HETATM 2742 O HOH A 623 38.606 -15.061 21.339 1.00 42.52 O HETATM 2743 O HOH A 624 36.674 -16.894 21.006 1.00 47.19 O HETATM 2744 O HOH A 625 0.137 9.582 5.794 1.00 56.53 O HETATM 2745 O HOH A 626 24.977 -4.882 38.140 1.00 57.34 O HETATM 2746 O HOH A 627 32.373 2.803 -11.210 1.00 42.04 O HETATM 2747 O HOH A 628 16.281 5.963 26.790 1.00 45.69 O HETATM 2748 O HOH A 629 14.821 7.995 27.837 1.00 69.48 O HETATM 2749 O HOH A 630 28.920 -3.772 -10.812 1.00 42.19 O HETATM 2750 O HOH A 631 26.388 18.522 -11.254 1.00 51.05 O HETATM 2751 O HOH A 632 45.628 -1.100 21.993 1.00 43.87 O HETATM 2752 O HOH A 633 20.144 6.780 30.672 1.00 51.34 O HETATM 2753 O HOH A 634 38.586 11.443 16.543 1.00 44.04 O HETATM 2754 O HOH B 26 12.184 -0.742 17.398 1.00 25.52 O HETATM 2755 O HOH B 124 7.671 5.199 13.803 1.00 37.32 O HETATM 2756 O HOH B 155 23.144 11.212 -8.136 1.00 36.09 O HETATM 2757 O HOH B 158 12.831 12.881 -3.551 1.00 38.93 O HETATM 2758 O HOH B 161 9.599 0.125 10.231 1.00 37.85 O HETATM 2759 O HOH B 188 13.841 14.491 -5.499 1.00 43.09 O HETATM 2760 O HOH B 201 18.861 9.098 -9.836 1.00 43.81 O HETATM 2761 O HOH B 202 24.474 11.706 -10.868 1.00 52.91 O HETATM 2762 O HOH B 204 19.632 5.371 -13.054 1.00 56.80 O HETATM 2763 O HOH B 205 8.543 1.841 4.349 1.00 52.99 O HETATM 2764 O HOH B 206 4.118 4.635 -3.020 1.00 57.59 O HETATM 2765 O HOH B 208 17.134 15.474 -7.828 1.00 60.30 O HETATM 2766 O HOH B 209 24.845 13.827 -12.295 1.00 46.09 O CONECT 328 1474 CONECT 860 1112 CONECT 1112 860 CONECT 1474 328 CONECT 1620 2120 CONECT 1758 2048 CONECT 2048 1758 CONECT 2120 1620 CONECT 2388 2484 CONECT 2484 2388 MASTER 375 0 0 8 22 0 0 6 2725 2 10 33 END
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Related entries of code: 3sri
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Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
3sri
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
Plasmodium falciparum Apical membrane antigen 1, AMA1 CAMP
Ligand Name
29aa PfRON2-sp2 peptide
EC.Number
E.C.-.-.-.-
Resolution
1.6(Å)
Affinity (Kd/Ki/IC50)
Kd=165nM
Release Year
2012
Protein/NA Sequence
Check fasta file
Primary Reference
(2012) Plos Pathog. Vol. 8: pp. e1002755-e1002755
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P50489
Q8IKV6
Entrez Gene ID
NCBI Entrez Gene ID:
812077
ASD
Information of known allosteric effects of PDB entries
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