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Related entries of code: 4ajw
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2wxfRCSB PDB    PDBbind940aa, >2WXF_1|Chain... at 100%
2wxgRCSB PDB    PDBbind940aa, >2WXG_1|Chain... at 100%
2wxhRCSB PDB    PDBbind940aa, >2WXH_1|Chain... at 100%
2wxiRCSB PDB    PDBbind940aa, >2WXI_1|Chain... at 100%
2wxjRCSB PDB    PDBbind940aa, >2WXJ_1|Chain... at 100%
2wxkRCSB PDB    PDBbind940aa, >2WXK_1|Chain... at 100%
2wxlRCSB PDB    PDBbind940aa, >2WXL_1|Chain... at 100%
2wxmRCSB PDB    PDBbind940aa, >2WXM_1|Chain... at 100%
2wxnRCSB PDB    PDBbind940aa, >2WXN_1|Chain... at 100%
2wxoRCSB PDB    PDBbind940aa, >2WXO_1|Chain... at 100%
2wxpRCSB PDB    PDBbind940aa, >2WXP_1|Chain... at 100%
2wxqRCSB PDB    PDBbind940aa, >2WXQ_1|Chain... at 100%
2x38RCSB PDB    PDBbind940aa, >2X38_1|Chain... at 100%
4v0iRCSB PDB    PDBbind940aa, >4V0I_1|Chains... at 100%
4xe0RCSB PDB    PDBbind939aa, >4XE0_1|Chain... at 100%
5dxuRCSB PDB    PDBbind1043aa, >5DXU_1|Chain... at 94%
5l72RCSB PDB    PDBbind940aa, >5L72_1|Chain... at 100%
5ncyRCSB PDB    PDBbind939aa, >5NCY_1|Chain... at 99%
5nczRCSB PDB    PDBbind936aa, >5NCZ_1|Chain... at 99%
5ngbRCSB PDB    PDBbind1079aa, >5NGB_1|Chain... *
5o83RCSB PDB    PDBbind941aa, >5O83_1|Chain... at 100%
5t27RCSB PDB    PDBbind939aa, >5T27_1|Chain... at 100%
5t28RCSB PDB    PDBbind939aa, >5T28_1|Chain... at 100%
5t2bRCSB PDB    PDBbind939aa, >5T2B_1|Chain... at 100%
5t2dRCSB PDB    PDBbind939aa, >5T2D_1|Chain... at 100%
5t2gRCSB PDB    PDBbind939aa, >5T2G_1|Chain... at 100%
5t2iRCSB PDB    PDBbind939aa, >5T2I_1|Chain... at 100%
5t2lRCSB PDB    PDBbind939aa, >5T2L_1|Chain... at 100%
5t2mRCSB PDB    PDBbind939aa, >5T2M_1|Chain... at 100%
5ubtRCSB PDB    PDBbind1013aa, >5UBT_1|Chain... at 94%
5vlrRCSB PDB    PDBbind1013aa, >5VLR_1|Chain... at 94%
6dgtRCSB PDB    PDBbind938aa, >6DGT_1|Chain... at 100%
6eyzRCSB PDB    PDBbind1051aa, >6EYZ_1|Chain... at 100%
6ez6RCSB PDB    PDBbind1051aa, >6EZ6_1|Chain... at 100%
6ftnRCSB PDB    PDBbind939aa, >6FTN_1|Chain... at 100%
6g6wRCSB PDB    PDBbind1072aa, >6G6W_1|Chain... at 94%
6q6yRCSB PDB    PDBbind940aa, >6Q6Y_1|Chain... at 100%
6q73RCSB PDB    PDBbind940aa, >6Q73_1|Chain... at 100%
6q74RCSB PDB    PDBbind940aa, >6Q74_1|Chain... at 100%
6pyuRCSB PDB    PDBbind1018aa, >6PYU_1|Chain... at 94%
6pyrRCSB PDB    PDBbind1018aa, >6PYR_1|Chain... at 94%
6ocoRCSB PDB    PDBbind1015aa, >6OCO_1|Chain... at 94%
6mumRCSB PDB    PDBbind940aa, >6MUM_1|Chains... at 100%
6mulRCSB PDB    PDBbind940aa, >6MUL_1|Chains... at 100%
6gy0RCSB PDB    PDBbind938aa, >6GY0_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4ajw
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namephosphoinositide-3 kinase (PI3K) delta
Ligand NameVWN
EC.Number E.C.2.7.1.153
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)IC50=1395nM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Med.Chem. Vol. 55: pp. 4788-4805
Ligand Properties
Formula C17H19N5O2
Molecular Weight 325.365
Exact Mass 325.154
No. of atoms 43
No. of bonds 46
Polar Surface Area 76.04
LOGP Value 0.38      (Computed with XLOGP3)
1.15      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 3
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O35904  
Entrez Gene IDNCBI Entrez Gene ID: 18707  
ASDInformation of known allosteric effects of PDB entries
 
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