Browse entries in the PDBbind-CN Database

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Related entries of code: 4bzs
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2c6nRCSB PDB    PDBbind612aa, >2C6N_1|Chains... at 98%
2xydRCSB PDB    PDBbind610aa, >2XYD_1|Chains... at 99%
3nxqRCSB PDB    PDBbind629aa, >3NXQ_1|Chains... *
4bxkRCSB PDB    PDBbind629aa, >4BXK_1|Chains... at 100%
4ca6RCSB PDB    PDBbind610aa, >4CA6_1|Chains... at 99%
6en5RCSB PDB    PDBbind629aa, >6EN5_1|Chains... at 100%
6en6RCSB PDB    PDBbind629aa, >6EN6_1|Chains... at 100%
6f9rRCSB PDB    PDBbind629aa, >6F9R_1|Chains... at 99%
6f9vRCSB PDB    PDBbind629aa, >6F9V_1|Chains... at 99%
6h5xRCSB PDB    PDBbind629aa, >6H5X_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2xhmRCSB PDB    PDBbindK26
4bzrRCSB PDB    PDBbindK26
5l44RCSB PDB    PDBbindK26
Entry Information
PDB ID4bzs
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHuman angiotenisn converting enzyme N-domain
Ligand NameK26
EC.Number E.C.3.2.1
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)Ki=75nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) Acs Med.Chem.Lett. Vol. 5: pp. 346-351
Ligand Properties
Formula C25H35N3O8P
Molecular Weight 536.534
Exact Mass 536.216
No. of atoms 72
No. of bonds 73
Polar Surface Area 202.04
LOGP Value 1.37      (Computed with XLOGP3)
2.27      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 5
No. of Hydrogen Bond Acceptors: 8
No. of Rotatable Bonds: 16
No. of Nitrogen and Oxygen Atoms: 11
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P12821  
Entrez Gene IDNCBI Entrez Gene ID: 1636  
ASDInformation of known allosteric effects of PDB entries
 
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