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Browse entries in the PDBbind-CN Database

HEADER    METAL BINDING PROTEIN/DNA               08-MAY-12   4F2J              
TITLE     CRYSTAL STRUCTURE OF ZNF217 BOUND TO DNA, P6522 CRYSTAL FORM          
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: 5'-D(*TP*TP*TP*GP*CP*AP*GP*AP*AP*TP*CP*GP*AP*TP*TP*CP*TP*GP
COMPND   3 *CP*A)-3';                                                           
COMPND   4 CHAIN: A;                                                            
COMPND   5 ENGINEERED: YES;                                                     
COMPND   6 MOL_ID: 2;                                                           
COMPND   7 MOLECULE: ZINC FINGER PROTEIN 217;                                   
COMPND   8 CHAIN: C;                                                            
COMPND   9 FRAGMENT: ZINC FINGERS 6 AND 7 (UNP RESIDUES 469-523);               
COMPND  10 SYNONYM: TRANSCRIPTION FACTOR ZNF217;                                
COMPND  11 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 SYNTHETIC: YES;                                                      
SOURCE   3 MOL_ID: 2;                                                           
SOURCE   4 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   5 ORGANISM_COMMON: HUMAN;                                              
SOURCE   6 ORGANISM_TAXID: 9606;                                                
SOURCE   7 GENE: ZNF217, ZABC1;                                                 
SOURCE   8 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE   9 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE  10 EXPRESSION_SYSTEM_STRAIN: ROSETTA 2;                                 
SOURCE  11 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE  12 EXPRESSION_SYSTEM_PLASMID: PMAL                                      
KEYWDS    ZINC FINGER, TRANSCRIPTION FACTOR, DNA BINDING, NUCLEUS, METAL        
KEYWDS   2 BINDING PROTEIN-DNA COMPLEX                                          
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    M.S.VANDEVENNE,D.A.JACQUES,J.M.GUSS,J.P.MACKAY                        
REVDAT   2   04-SEP-13 4F2J    1       JRNL                                     
REVDAT   1   27-FEB-13 4F2J    0                                                
JRNL        AUTH   M.S.VANDEVENNE,D.A.JACQUES,C.ARTUZ,C.D.NGUYEN,A.H.KWAN,      
JRNL        AUTH 2 D.J.SEGAL,J.M.MATTHEWS,M.CROSSLEY,J.M.GUSS,J.P.MACKAY        
JRNL        TITL   NEW INSIGHTS INTO DNA RECOGNITION BY ZINC FINGERS REVEALED   
JRNL        TITL 2 BY STRUCTURAL ANALYSIS OF THE ONCOPROTEIN ZNF217             
JRNL        REF    J.BIOL.CHEM.                  V. 288 10616 2013              
JRNL        REFN                   ISSN 0021-9258                               
JRNL        PMID   23436653                                                     
JRNL        DOI    10.1074/JBC.M112.441451                                      
REMARK   2                                                                      
REMARK   2 RESOLUTION.    2.64 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.5.0109                                      
REMARK   3   AUTHORS     : MURSHUDOV,VAGIN,DODSON                               
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 2.64                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 48.31                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.000                          
REMARK   3   COMPLETENESS FOR RANGE        (%) : 99.0                           
REMARK   3   NUMBER OF REFLECTIONS             : 7467                           
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.253                           
REMARK   3   R VALUE            (WORKING SET) : 0.252                           
REMARK   3   FREE R VALUE                     : 0.264                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 4.600                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 344                             
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 2.64                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 2.71                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 508                          
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 99.07                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.4220                       
REMARK   3   BIN FREE R VALUE SET COUNT          : 22                           
REMARK   3   BIN FREE R VALUE                    : 0.4200                       
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 449                                     
REMARK   3   NUCLEIC ACID ATOMS       : 406                                     
REMARK   3   HETEROGEN ATOMS          : 2                                       
REMARK   3   SOLVENT ATOMS            : 0                                       
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 96.52                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : 5.31000                                              
REMARK   3    B22 (A**2) : 5.31000                                              
REMARK   3    B33 (A**2) : -7.97000                                             
REMARK   3    B12 (A**2) : 2.66000                                              
REMARK   3    B13 (A**2) : 0.00000                                              
REMARK   3    B23 (A**2) : 0.00000                                              
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): 0.327         
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.247         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): 0.285         
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 32.121        
REMARK   3                                                                      
REMARK   3 CORRELATION COEFFICIENTS.                                            
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.924                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.969                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):   917 ; 0.016 ; 0.021       
REMARK   3   BOND LENGTHS OTHERS               (A):   515 ; 0.002 ; 0.020       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  1319 ; 2.318 ; 2.489       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  1253 ; 1.125 ; 3.000       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):    51 ; 5.450 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):    27 ;29.747 ;21.111       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):    79 ;16.056 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):     5 ;14.995 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   137 ; 0.083 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):   723 ; 0.008 ; 0.020       
REMARK   3   GENERAL PLANES OTHERS             (A):   159 ; 0.001 ; 0.020       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):   258 ; 2.263 ; 2.000       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):   104 ; 0.569 ; 2.000       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):   411 ; 3.819 ; 3.000       
REMARK   3   MAIN-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):   659 ; 8.122 ; 4.000       
REMARK   3   SIDE-CHAIN BOND OTHER ATOMS    (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):   908 ;10.185 ; 6.000       
REMARK   3   SIDE-CHAIN ANGLE OTHER ATOMS   (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B REFINED ATOMS     (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   LONG RANGE B OTHER ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3 ANISOTROPIC THERMAL FACTOR RESTRAINTS.    COUNT   RMS   WEIGHT       
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : 2                                          
REMARK   3                                                                      
REMARK   3   TLS GROUP : 1                                                      
REMARK   3    NUMBER OF COMPONENTS GROUP : 1                                    
REMARK   3    COMPONENTS        C SSSEQI   TO  C SSSEQI                         
REMARK   3    RESIDUE RANGE :   A     0        A    19                          
REMARK   3    ORIGIN FOR THE GROUP (A):  31.2256  38.2133  38.2300              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.4927 T22:   0.3269                                     
REMARK   3      T33:   0.5350 T12:   0.2084                                     
REMARK   3      T13:   0.0015 T23:  -0.0822                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   8.1461 L22:   4.6998                                     
REMARK   3      L33:  14.5824 L12:   5.1317                                     
REMARK   3      L13:   9.1287 L23:   5.3321                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:   0.0514 S12:   0.1885 S13:  -0.3932                       
REMARK   3      S21:  -0.0394 S22:   0.0519 S23:   0.0358                       
REMARK   3      S31:   1.2167 S32:   0.1555 S33:  -0.1034                       
REMARK   3                                                                      
REMARK   3   TLS GROUP : 2                                                      
REMARK   3    NUMBER OF COMPONENTS GROUP : 2                                    
REMARK   3    COMPONENTS        C SSSEQI   TO  C SSSEQI                         
REMARK   3    RESIDUE RANGE :   C   471        C   522                          
REMARK   3    RESIDUE RANGE :   C   601        C   602                          
REMARK   3    ORIGIN FOR THE GROUP (A):  18.1557  42.2507  30.4185              
REMARK   3    T TENSOR                                                          
REMARK   3      T11:   0.4751 T22:   0.6739                                     
REMARK   3      T33:   0.5634 T12:  -0.1111                                     
REMARK   3      T13:  -0.1624 T23:  -0.1764                                     
REMARK   3    L TENSOR                                                          
REMARK   3      L11:   7.4251 L22:   9.3960                                     
REMARK   3      L33:  27.8988 L12:   0.0596                                     
REMARK   3      L13:  -2.5538 L23:   4.3468                                     
REMARK   3    S TENSOR                                                          
REMARK   3      S11:  -0.3465 S12:  -0.5084 S13:   0.0928                       
REMARK   3      S21:  -0.1847 S22:  -0.4259 S23:   0.7424                       
REMARK   3      S31:  -0.2368 S32:  -2.0778 S33:   0.7723                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : MASK                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.40                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING   
REMARK   3  POSITIONS U VALUES                                                  
REMARK   4                                                                      
REMARK   4 4F2J COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 18-MAY-12.                  
REMARK 100 THE RCSB ID CODE IS RCSB072373.                                      
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 06-SEP-11; 15-SEP-11               
REMARK 200  TEMPERATURE           (KELVIN) : 100; 100                           
REMARK 200  PH                             : 7.0; 7.0                           
REMARK 200  NUMBER OF CRYSTALS USED        : 2                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : N; N                               
REMARK 200  RADIATION SOURCE               : ROTATING ANODE; NULL               
REMARK 200  BEAMLINE                       : NULL; NULL                         
REMARK 200  X-RAY GENERATOR MODEL          : RIGAKU MICROMAX-007 HF; NULL       
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M; M                               
REMARK 200  WAVELENGTH OR RANGE        (A) : 1.5418; NULL                       
REMARK 200  MONOCHROMATOR                  : OSMIC VARIMAX; OSMIC VARIMAX       
REMARK 200  OPTICS                         : NULL; NULL                         
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : IMAGE PLATE; IMAGE PLATE           
REMARK 200  DETECTOR MANUFACTURER          : MAR SCANNER 345 MM PLATE; MAR      
REMARK 200                                   SCANNER 345 MM PLATE               
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : DENZO                              
REMARK 200  DATA SCALING SOFTWARE          : SCALEPACK                          
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 7517                               
REMARK 200  RESOLUTION RANGE HIGH      (A) : 2.640                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 99.000                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 0.000                              
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 98.5                               
REMARK 200  DATA REDUNDANCY                : 2.500                              
REMARK 200  R MERGE                    (I) : 0.09100                            
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 9.3000                             
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.64                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 2.68                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 95.0                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 1.80                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.18800                            
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : NULL                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH; SINGLE WAVELENGTH           
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: SIRAS                        
REMARK 200 SOFTWARE USED: SOLVE                                                 
REMARK 200 STARTING MODEL: NULL                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 71.87                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 4.37                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 20% PEG 3350, 0.2M SODIUM SULFATE, PH    
REMARK 280  7.0, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 293K. 20% PEG       
REMARK 280  3350, 0.2M SODIUM SULFATE, 10MM TRIMETHYLLEAD ACETATE, PH 7.0,      
REMARK 280  VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 293K                     
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 65 2 2                         
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -Y,X-Y,Z+2/3                                            
REMARK 290       3555   -X+Y,-X,Z+1/3                                           
REMARK 290       4555   -X,-Y,Z+1/2                                             
REMARK 290       5555   Y,-X+Y,Z+1/6                                            
REMARK 290       6555   X-Y,X,Z+5/6                                             
REMARK 290       7555   Y,X,-Z+2/3                                              
REMARK 290       8555   X-Y,-Y,-Z                                               
REMARK 290       9555   -X,-X+Y,-Z+1/3                                          
REMARK 290      10555   -Y,-X,-Z+1/6                                            
REMARK 290      11555   -X+Y,Y,-Z+1/2                                           
REMARK 290      12555   X,X-Y,-Z+5/6                                            
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -0.500000 -0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.866025 -0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000      161.69467            
REMARK 290   SMTRY1   3 -0.500000  0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   3 -0.866025 -0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   3  0.000000  0.000000  1.000000       80.84733            
REMARK 290   SMTRY1   4 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   4  0.000000  0.000000  1.000000      121.27100            
REMARK 290   SMTRY1   5  0.500000  0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   5 -0.866025  0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   5  0.000000  0.000000  1.000000       40.42367            
REMARK 290   SMTRY1   6  0.500000 -0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   6  0.866025  0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   6  0.000000  0.000000  1.000000      202.11833            
REMARK 290   SMTRY1   7 -0.500000  0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   7  0.866025  0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   7  0.000000  0.000000 -1.000000      161.69467            
REMARK 290   SMTRY1   8  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   8  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   8  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   9 -0.500000 -0.866025  0.000000        0.00000            
REMARK 290   SMTRY2   9 -0.866025  0.500000  0.000000        0.00000            
REMARK 290   SMTRY3   9  0.000000  0.000000 -1.000000       80.84733            
REMARK 290   SMTRY1  10  0.500000 -0.866025  0.000000        0.00000            
REMARK 290   SMTRY2  10 -0.866025 -0.500000  0.000000        0.00000            
REMARK 290   SMTRY3  10  0.000000  0.000000 -1.000000       40.42367            
REMARK 290   SMTRY1  11 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2  11  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3  11  0.000000  0.000000 -1.000000      121.27100            
REMARK 290   SMTRY1  12  0.500000  0.866025  0.000000        0.00000            
REMARK 290   SMTRY2  12  0.866025 -0.500000  0.000000        0.00000            
REMARK 290   SMTRY3  12  0.000000  0.000000 -1.000000      202.11833            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC                 
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 5120 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 13010 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -35.0 KCAL/MOL                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, A                                  
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT1   2 -0.500000 -0.866025  0.000000       85.39200            
REMARK 350   BIOMT2   2 -0.866025  0.500000  0.000000       49.30109            
REMARK 350   BIOMT3   2  0.000000  0.000000 -1.000000       80.84733            
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     GLY C   467                                                      
REMARK 465     SER C   468                                                      
REMARK 465     SER C   469                                                      
REMARK 465     SER C   470                                                      
REMARK 465     LYS C   523                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS                                             
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC             
REMARK 500 SYMMETRY ARE IN CLOSE CONTACT.  AN ATOM LOCATED WITHIN 0.15          
REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A           
REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375             
REMARK 500 INSTEAD OF REMARK 500.  ATOMS WITH NON-BLANK ALTERNATE               
REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS.            
REMARK 500                                                                      
REMARK 500 DISTANCE CUTOFF:                                                     
REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS              
REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS                  
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI  SSYMOP   DISTANCE          
REMARK 500   OP1   DG A    11     NH2  ARG C   520     9765     1.99            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500     DC A  10   O3'    DC A  10   C3'    -0.059                       
REMARK 500     DT A  13   C2     DT A  13   N3      0.061                       
REMARK 500     DC A  15   O3'    DC A  15   C3'    -0.048                       
REMARK 500     DT A  16   C1'    DT A  16   N1      0.088                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500     DT A   0   C3' -  O3' -  P   ANGL. DEV. =   7.8 DEGREES          
REMARK 500     DG A   3   O4' -  C4' -  C3' ANGL. DEV. =  -2.5 DEGREES          
REMARK 500     DG A   6   O4' -  C1' -  C2' ANGL. DEV. =  -6.1 DEGREES          
REMARK 500     DG A   6   O4' -  C1' -  N9  ANGL. DEV. =   4.5 DEGREES          
REMARK 500     DA A   5   C3' -  O3' -  P   ANGL. DEV. =  11.2 DEGREES          
REMARK 500     DA A   7   O4' -  C1' -  N9  ANGL. DEV. =  -7.6 DEGREES          
REMARK 500     DA A   8   O5' -  C5' -  C4' ANGL. DEV. =  -5.1 DEGREES          
REMARK 500     DA A   8   C1' -  O4' -  C4' ANGL. DEV. =  -7.0 DEGREES          
REMARK 500     DA A   8   O4' -  C1' -  N9  ANGL. DEV. =  -4.6 DEGREES          
REMARK 500     DA A  12   O4' -  C4' -  C3' ANGL. DEV. =  -2.6 DEGREES          
REMARK 500     DA A  12   O4' -  C1' -  C2' ANGL. DEV. =  -6.2 DEGREES          
REMARK 500     DA A  12   C6  -  N1  -  C2  ANGL. DEV. =  -4.0 DEGREES          
REMARK 500     DA A  12   C6  -  C5  -  N7  ANGL. DEV. =  -4.3 DEGREES          
REMARK 500     DA A  12   N1  -  C6  -  N6  ANGL. DEV. =   5.9 DEGREES          
REMARK 500     DA A  12   C5  -  C6  -  N6  ANGL. DEV. =  -7.3 DEGREES          
REMARK 500     DT A  13   O4' -  C4' -  C3' ANGL. DEV. = -10.9 DEGREES          
REMARK 500     DT A  13   O4' -  C1' -  C2' ANGL. DEV. =  -5.8 DEGREES          
REMARK 500     DT A  13   C2  -  N3  -  C4  ANGL. DEV. =  -4.4 DEGREES          
REMARK 500     DT A  13   N3  -  C4  -  O4  ANGL. DEV. =   6.0 DEGREES          
REMARK 500     DT A  13   C5  -  C4  -  O4  ANGL. DEV. =  -7.3 DEGREES          
REMARK 500     DT A  14   O5' -  P   -  OP1 ANGL. DEV. =   9.5 DEGREES          
REMARK 500     DT A  14   O5' -  P   -  OP2 ANGL. DEV. =  -7.0 DEGREES          
REMARK 500     DT A  14   C3' -  C2' -  C1' ANGL. DEV. =  -5.6 DEGREES          
REMARK 500     DT A  14   O3' -  P   -  OP2 ANGL. DEV. =   8.4 DEGREES          
REMARK 500     DC A  15   O4' -  C4' -  C3' ANGL. DEV. =  -6.0 DEGREES          
REMARK 500     DC A  15   C4' -  C3' -  C2' ANGL. DEV. =  -6.0 DEGREES          
REMARK 500     DT A  16   O4' -  C4' -  C3' ANGL. DEV. =  -3.8 DEGREES          
REMARK 500     DT A  16   N3  -  C4  -  O4  ANGL. DEV. =   4.0 DEGREES          
REMARK 500     DT A  16   C4  -  C5  -  C7  ANGL. DEV. =  -4.7 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ARG C 481      -16.51    -47.35                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 620                                                                      
REMARK 620 METAL COORDINATION                                                   
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):                             
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN C 602  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 HIS C 493   NE2                                                    
REMARK 620 2 HIS C 489   NE2 105.9                                              
REMARK 620 3 CYS C 473   SG   90.3 101.5                                        
REMARK 620 4 CYS C 476   SG  136.0 109.8 106.7                                  
REMARK 620 N                    1     2     3                                   
REMARK 620                                                                      
REMARK 620 COORDINATION ANGLES FOR:  M RES CSSEQI METAL                         
REMARK 620                              ZN C 601  ZN                            
REMARK 620 N RES CSSEQI ATOM                                                    
REMARK 620 1 CYS C 504   SG                                                     
REMARK 620 2 CYS C 501   SG  119.0                                              
REMARK 620 3 HIS C 517   NE2 111.6 108.2                                        
REMARK 620 4 HIS C 522   NE2 123.5 110.2  75.0                                  
REMARK 620 N                    1     2     3                                   
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN C 601                  
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN C 602                  
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 3UK3   RELATED DB: PDB                                   
REMARK 900 CRYSTAL STRUCTURE OF ZNF217 BOUND TO DNA                             
DBREF  4F2J C  469   523  UNP    O75362   ZN217_HUMAN    469    523             
DBREF  4F2J A    0    19  PDB    4F2J     4F2J             0     19             
SEQADV 4F2J GLY C  467  UNP  O75362              EXPRESSION TAG                 
SEQADV 4F2J SER C  468  UNP  O75362              EXPRESSION TAG                 
SEQRES   1 A   20   DT  DT  DT  DG  DC  DA  DG  DA  DA  DT  DC  DG  DA          
SEQRES   2 A   20   DT  DT  DC  DT  DG  DC  DA                                  
SEQRES   1 C   57  GLY SER SER SER ARG GLU CYS SER TYR CYS GLY LYS PHE          
SEQRES   2 C   57  PHE ARG SER ASN TYR TYR LEU ASN ILE HIS LEU ARG THR          
SEQRES   3 C   57  HIS THR GLY GLU LYS PRO TYR LYS CYS GLU PHE CYS GLU          
SEQRES   4 C   57  TYR ALA ALA ALA GLN LYS THR SER LEU ARG TYR HIS LEU          
SEQRES   5 C   57  GLU ARG HIS HIS LYS                                          
HET     ZN  C 601       1                                                       
HET     ZN  C 602       1                                                       
HETNAM      ZN ZINC ION                                                         
FORMUL   3   ZN    2(ZN 2+)                                                     
HELIX    1   1 SER C  482  GLY C  495  1                                  14    
HELIX    2   2 GLN C  510  HIS C  522  1                                  13    
SHEET    1   A 2 TYR C 499  LYS C 500  0                                        
SHEET    2   A 2 ALA C 507  ALA C 508 -1  O  ALA C 508   N  TYR C 499           
LINK         NE2 HIS C 493                ZN    ZN C 602     1555   1555  1.98  
LINK         NE2 HIS C 489                ZN    ZN C 602     1555   1555  2.00  
LINK         SG  CYS C 473                ZN    ZN C 602     1555   1555  2.02  
LINK         SG  CYS C 504                ZN    ZN C 601     1555   1555  2.03  
LINK         SG  CYS C 501                ZN    ZN C 601     1555   1555  2.05  
LINK         NE2 HIS C 517                ZN    ZN C 601     1555   1555  2.14  
LINK         SG  CYS C 476                ZN    ZN C 602     1555   1555  2.29  
LINK         NE2 HIS C 522                ZN    ZN C 601     1555   1555  2.34  
SITE     1 AC1  4 CYS C 501  CYS C 504  HIS C 517  HIS C 522                    
SITE     1 AC2  4 CYS C 473  CYS C 476  HIS C 489  HIS C 493                    
CRYST1   56.928   56.928  242.542  90.00  90.00 120.00 P 65 2 2     12          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.017566  0.010142  0.000000        0.00000                         
SCALE2      0.000000  0.020284  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.004123        0.00000                         
ATOM      1  O5'  DT A   0      15.218  25.547  11.837  1.00129.25           O  
ANISOU    1  O5'  DT A   0    21674  14073  13364  -4711  -2593  -2831       O  
ATOM      2  C5'  DT A   0      14.363  26.619  11.458  1.00130.79           C  
ANISOU    2  C5'  DT A   0    21521  14577  13598  -5109  -2755  -2411       C  
ATOM      3  C4'  DT A   0      14.021  27.526  12.638  1.00129.84           C  
ANISOU    3  C4'  DT A   0    20937  14486  13909  -4930  -2770  -2062       C  
ATOM      4  O4'  DT A   0      14.006  26.754  13.875  1.00129.49           O  
ANISOU    4  O4'  DT A   0    21000  14115  14084  -4729  -2653  -2102       O  
ATOM      5  C3'  DT A   0      14.957  28.706  12.924  1.00119.74           C  
ANISOU    5  C3'  DT A   0    19334  13455  12708  -4619  -2646  -1963       C  
ATOM      6  O3'  DT A   0      14.109  29.787  13.369  1.00114.47           O  
ANISOU    6  O3'  DT A   0    18251  12867  12374  -4656  -2935  -1636       O  
ATOM      7  C2'  DT A   0      15.902  28.056  13.933  1.00115.40           C  
ANISOU    7  C2'  DT A   0    18877  12694  12276  -4129  -2330  -2198       C  
ATOM      8  C1'  DT A   0      14.879  27.348  14.807  1.00112.01           C  
ANISOU    8  C1'  DT A   0    18530  11947  12083  -4264  -2439  -2075       C  
ATOM      9  N1   DT A   0      15.335  26.279  15.752  1.00112.55           N  
ANISOU    9  N1   DT A   0    18962  11586  12218  -4030  -2358  -2227       N  
ATOM     10  C2   DT A   0      14.355  25.698  16.547  1.00117.23           C  
ANISOU   10  C2   DT A   0    19662  11993  12887  -4401  -2496  -2032       C  
ATOM     11  O2   DT A   0      13.171  26.001  16.497  1.00125.79           O  
ANISOU   11  O2   DT A   0    20442  13362  13991  -4844  -2609  -1841       O  
ATOM     12  N3   DT A   0      14.797  24.731  17.413  1.00112.92           N  
ANISOU   12  N3   DT A   0    19594  10962  12349  -4294  -2558  -2092       N  
ATOM     13  C4   DT A   0      16.101  24.283  17.567  1.00112.62           C  
ANISOU   13  C4   DT A   0    19891  10565  12336  -3704  -2543  -2402       C  
ATOM     14  O4   DT A   0      16.416  23.414  18.378  1.00103.74           O  
ANISOU   14  O4   DT A   0    19271   8900  11247  -3612  -2758  -2432       O  
ATOM     15  C5   DT A   0      17.079  24.919  16.713  1.00112.49           C  
ANISOU   15  C5   DT A   0    19588  10899  12255  -3254  -2322  -2713       C  
ATOM     16  C7   DT A   0      18.516  24.485  16.819  1.00113.87           C  
ANISOU   16  C7   DT A   0    19936  10903  12425  -2567  -2285  -3210       C  
ATOM     17  C6   DT A   0      16.663  25.871  15.848  1.00108.86           C  
ANISOU   17  C6   DT A   0    18715  10949  11697  -3515  -2223  -2576       C  
ATOM     18  P    DT A   1      14.470  30.939  14.421  1.00120.10           P  
ANISOU   18  P    DT A   1    18547  13641  13443  -4259  -2941  -1473       P  
ATOM     19  OP1  DT A   1      13.734  32.161  14.040  1.00118.67           O  
ANISOU   19  OP1  DT A   1    18126  13537  13426  -4374  -3488  -1251       O  
ATOM     20  OP2  DT A   1      15.934  31.011  14.665  1.00110.08           O  
ANISOU   20  OP2  DT A   1    17363  12428  12034  -3970  -2591  -1576       O  
ATOM     21  O5'  DT A   1      13.720  30.360  15.708  1.00120.45           O  
ANISOU   21  O5'  DT A   1    18360  13605  13798  -4136  -2820  -1532       O  
ATOM     22  C5'  DT A   1      12.304  30.302  15.769  1.00113.33           C  
ANISOU   22  C5'  DT A   1    17178  12858  13023  -4413  -3085  -1529       C  
ATOM     23  C4'  DT A   1      11.906  30.137  17.221  1.00107.13           C  
ANISOU   23  C4'  DT A   1    16020  12231  12453  -4321  -2905  -1595       C  
ATOM     24  O4'  DT A   1      12.626  29.005  17.755  1.00103.25           O  
ANISOU   24  O4'  DT A   1    16004  11438  11789  -4350  -2570  -1608       O  
ATOM     25  C3'  DT A   1      12.201  31.299  18.183  1.00100.24           C  
ANISOU   25  C3'  DT A   1    14642  11523  11920  -3846  -2914  -1608       C  
ATOM     26  O3'  DT A   1      11.016  31.535  18.908  1.00102.00           O  
ANISOU   26  O3'  DT A   1    14232  12202  12322  -3929  -3046  -1799       O  
ATOM     27  C2'  DT A   1      13.291  30.800  19.115  1.00 90.55           C  
ANISOU   27  C2'  DT A   1    13658  10092  10654  -3634  -2490  -1576       C  
ATOM     28  C1'  DT A   1      13.025  29.299  19.073  1.00 98.40           C  
ANISOU   28  C1'  DT A   1    15133  10892  11363  -4073  -2367  -1593       C  
ATOM     29  N1   DT A   1      14.178  28.417  19.305  1.00 95.77           N  
ANISOU   29  N1   DT A   1    15383  10110  10896  -3893  -2162  -1615       N  
ATOM     30  C2   DT A   1      14.037  27.335  20.128  1.00102.54           C  
ANISOU   30  C2   DT A   1    16599  10730  11631  -4171  -2140  -1578       C  
ATOM     31  O2   DT A   1      13.001  27.067  20.697  1.00111.63           O  
ANISOU   31  O2   DT A   1    17574  12145  12696  -4690  -2196  -1498       O  
ATOM     32  N3   DT A   1      15.167  26.572  20.284  1.00104.46           N  
ANISOU   32  N3   DT A   1    17420  10455  11816  -3860  -2114  -1671       N  
ATOM     33  C4   DT A   1      16.407  26.758  19.698  1.00 99.90           C  
ANISOU   33  C4   DT A   1    16954   9745  11258  -3299  -2017  -1890       C  
ATOM     34  O4   DT A   1      17.357  25.986  19.905  1.00 86.73           O  
ANISOU   34  O4   DT A   1    15736   7659   9558  -2954  -2064  -2102       O  
ATOM     35  C5   DT A   1      16.478  27.911  18.820  1.00 96.70           C  
ANISOU   35  C5   DT A   1    16107   9761  10871  -3198  -1942  -1888       C  
ATOM     36  C7   DT A   1      17.759  28.254  18.102  1.00 98.44           C  
ANISOU   36  C7   DT A   1    16337  10106  10959  -2821  -1799  -2119       C  
ATOM     37  C6   DT A   1      15.375  28.666  18.664  1.00 92.54           C  
ANISOU   37  C6   DT A   1    15164   9560  10438  -3499  -2071  -1709       C  
ATOM     38  P    DT A   2      10.746  32.902  19.653  1.00112.51           P  
ANISOU   38  P    DT A   2    14849  13838  14061  -3426  -3307  -2005       P  
ATOM     39  OP1  DT A   2       9.332  33.296  19.449  1.00110.97           O  
ANISOU   39  OP1  DT A   2    14024  14119  14021  -3483  -3753  -2335       O  
ATOM     40  OP2  DT A   2      11.878  33.830  19.341  1.00102.91           O  
ANISOU   40  OP2  DT A   2    13915  12213  12972  -3014  -3449  -1802       O  
ATOM     41  O5'  DT A   2      10.810  32.367  21.151  1.00108.95           O  
ANISOU   41  O5'  DT A   2    14150  13699  13545  -3516  -2833  -2111       O  
ATOM     42  C5'  DT A   2       9.803  31.476  21.555  1.00108.85           C  
ANISOU   42  C5'  DT A   2    13913  14170  13274  -4115  -2694  -2252       C  
ATOM     43  C4'  DT A   2      10.224  30.745  22.808  1.00107.16           C  
ANISOU   43  C4'  DT A   2    13854  14027  12834  -4396  -2267  -2154       C  
ATOM     44  O4'  DT A   2      11.453  30.006  22.613  1.00 97.68           O  
ANISOU   44  O4'  DT A   2    13540  12061  11511  -4335  -2095  -1819       O  
ATOM     45  C3'  DT A   2      10.498  31.656  23.992  1.00106.58           C  
ANISOU   45  C3'  DT A   2    13203  14298  12993  -3958  -2147  -2355       C  
ATOM     46  O3'  DT A   2       9.561  31.330  24.993  1.00113.05           O  
ANISOU   46  O3'  DT A   2    13438  15965  13551  -4502  -1979  -2624       O  
ATOM     47  C2'  DT A   2      11.940  31.342  24.401  1.00 98.89           C  
ANISOU   47  C2'  DT A   2    12896  12678  11999  -3728  -1883  -2019       C  
ATOM     48  C1'  DT A   2      12.021  29.915  23.903  1.00 94.56           C  
ANISOU   48  C1'  DT A   2    13139  11699  11091  -4283  -1838  -1766       C  
ATOM     49  N1   DT A   2      13.353  29.353  23.722  1.00 82.37           N  
ANISOU   49  N1   DT A   2    12373   9404   9519  -4011  -1752  -1546       N  
ATOM     50  C2   DT A   2      13.759  28.240  24.449  1.00 94.43           C  
ANISOU   50  C2   DT A   2    14498  10579  10800  -4331  -1695  -1381       C  
ATOM     51  O2   DT A   2      13.092  27.672  25.292  1.00111.17           O  
ANISOU   51  O2   DT A   2    16615  12980  12644  -4986  -1687  -1307       O  
ATOM     52  N3   DT A   2      15.016  27.783  24.164  1.00 91.25           N  
ANISOU   52  N3   DT A   2    14732   9498  10442  -3896  -1716  -1334       N  
ATOM     53  C4   DT A   2      15.882  28.320  23.239  1.00 91.15           C  
ANISOU   53  C4   DT A   2    14727   9309  10597  -3303  -1682  -1448       C  
ATOM     54  O4   DT A   2      16.996  27.850  23.074  1.00 91.03           O  
ANISOU   54  O4   DT A   2    15158   8859  10568  -2928  -1681  -1532       O  
ATOM     55  C5   DT A   2      15.397  29.479  22.519  1.00 85.97           C  
ANISOU   55  C5   DT A   2    13510   9060  10097  -3186  -1719  -1501       C  
ATOM     56  C7   DT A   2      16.289  30.155  21.518  1.00 82.67           C  
ANISOU   56  C7   DT A   2    13128   8556   9725  -2784  -1729  -1546       C  
ATOM     57  C6   DT A   2      14.164  29.931  22.779  1.00 77.44           C  
ANISOU   57  C6   DT A   2    11883   8471   9070  -3484  -1809  -1546       C  
ATOM     58  P    DG A   3       9.372  32.360  26.191  1.00121.68           P  
ANISOU   58  P    DG A   3    13613  17780  14841  -4114  -1909  -3084       P  
ATOM     59  OP1  DG A   3       8.024  32.127  26.769  1.00126.23           O  
ANISOU   59  OP1  DG A   3    13329  19546  15086  -4746  -1834  -3571       O  
ATOM     60  OP2  DG A   3       9.804  33.695  25.698  1.00109.55           O  
ANISOU   60  OP2  DG A   3    11907  15855  13861  -3163  -2286  -3221       O  
ATOM     61  O5'  DG A   3      10.424  31.804  27.242  1.00113.58           O  
ANISOU   61  O5'  DG A   3    13127  16430  13597  -4299  -1518  -2719       O  
ATOM     62  C5'  DG A   3      10.191  30.487  27.712  1.00120.05           C  
ANISOU   62  C5'  DG A   3    14397  17362  13856  -5269  -1321  -2453       C  
ATOM     63  C4'  DG A   3      11.385  29.999  28.494  1.00117.66           C  
ANISOU   63  C4'  DG A   3    14816  16438  13450  -5267  -1149  -2049       C  
ATOM     64  O4'  DG A   3      12.552  29.859  27.664  1.00107.80           O  
ANISOU   64  O4'  DG A   3    14350  14136  12475  -4671  -1257  -1748       O  
ATOM     65  C3'  DG A   3      11.864  30.971  29.549  1.00114.27           C  
ANISOU   65  C3'  DG A   3    13853  16328  13235  -4760   -973  -2254       C  
ATOM     66  O3'  DG A   3      11.116  30.754  30.734  1.00128.09           O  
ANISOU   66  O3'  DG A   3    15077  19064  14525  -5523   -766  -2465       O  
ATOM     67  C2'  DG A   3      13.350  30.648  29.684  1.00103.74           C  
ANISOU   67  C2'  DG A   3    13385  14011  12019  -4377   -937  -1819       C  
ATOM     68  C1'  DG A   3      13.611  29.647  28.580  1.00100.10           C  
ANISOU   68  C1'  DG A   3    13788  12770  11474  -4524  -1129  -1526       C  
ATOM     69  N9   DG A   3      14.856  29.689  27.810  1.00 85.96           N  
ANISOU   69  N9   DG A   3    12553  10143   9967  -3817  -1201  -1384       N  
ATOM     70  C8   DG A   3      15.183  30.555  26.802  1.00 74.72           C  
ANISOU   70  C8   DG A   3    10934   8592   8866  -3203  -1266  -1493       C  
ATOM     71  N7   DG A   3      16.329  30.276  26.237  1.00 73.73           N  
ANISOU   71  N7   DG A   3    11354   7866   8795  -2817  -1278  -1388       N  
ATOM     72  C5   DG A   3      16.798  29.150  26.907  1.00 79.63           C  
ANISOU   72  C5   DG A   3    12714   8205   9336  -3040  -1295  -1244       C  
ATOM     73  C6   DG A   3      17.998  28.394  26.755  1.00 82.74           C  
ANISOU   73  C6   DG A   3    13787   7928   9724  -2689  -1396  -1227       C  
ATOM     74  O6   DG A   3      18.951  28.547  25.993  1.00 83.84           O  
ANISOU   74  O6   DG A   3    14034   7844   9977  -2144  -1379  -1382       O  
ATOM     75  N1   DG A   3      18.078  27.340  27.627  1.00 85.32           N  
ANISOU   75  N1   DG A   3    14705   7867   9844  -3051  -1595  -1065       N  
ATOM     76  C2   DG A   3      17.121  27.042  28.543  1.00 94.73           C  
ANISOU   76  C2   DG A   3    15854   9385  10756  -3846  -1620   -871       C  
ATOM     77  N2   DG A   3      17.400  25.975  29.294  1.00106.30           N  
ANISOU   77  N2   DG A   3    18100  10316  11974  -4237  -1942   -645       N  
ATOM     78  N3   DG A   3      15.988  27.721  28.705  1.00 96.44           N  
ANISOU   78  N3   DG A   3    15319  10424  10900  -4251  -1413   -944       N  
ATOM     79  C4   DG A   3      15.891  28.775  27.863  1.00 84.48           C  
ANISOU   79  C4   DG A   3    13204   9198   9698  -3723  -1283  -1166       C  
ATOM     80  P    DC A   4      11.442  31.604  32.052  1.00136.69           P  
ANISOU   80  P    DC A   4    15551  20709  15676  -5223   -541  -2751       P  
ATOM     81  OP1  DC A   4      10.175  31.690  32.815  1.00141.62           O  
ANISOU   81  OP1  DC A   4    15170  22790  15850  -5934   -372  -3311       O  
ATOM     82  OP2  DC A   4      12.218  32.826  31.696  1.00122.08           O  
ANISOU   82  OP2  DC A   4    13541  18347  14497  -4027   -674  -2885       O  
ATOM     83  O5'  DC A   4      12.440  30.613  32.802  1.00126.68           O  
ANISOU   83  O5'  DC A   4    15298  18763  14070  -5699   -456  -2127       O  
ATOM     84  C5'  DC A   4      12.151  29.231  32.836  1.00127.54           C  
ANISOU   84  C5'  DC A   4    16173  18681  13606  -6770   -569  -1710       C  
ATOM     85  C4'  DC A   4      13.232  28.522  33.611  1.00126.47           C  
ANISOU   85  C4'  DC A   4    17002  17758  13291  -6959   -669  -1191       C  
ATOM     86  O4'  DC A   4      14.368  28.332  32.741  1.00112.76           O  
ANISOU   86  O4'  DC A   4    16038  14772  12033  -6087   -889   -950       O  
ATOM     87  C3'  DC A   4      13.770  29.289  34.818  1.00129.65           C  
ANISOU   87  C3'  DC A   4    16967  18545  13749  -6669   -429  -1318       C  
ATOM     88  O3'  DC A   4      14.181  28.375  35.813  1.00143.41           O  
ANISOU   88  O3'  DC A   4    19499  20011  14981  -7479   -569   -851       O  
ATOM     89  C2'  DC A   4      14.959  30.038  34.236  1.00115.74           C  
ANISOU   89  C2'  DC A   4    15336  15931  12710  -5342   -461  -1319       C  
ATOM     90  C1'  DC A   4      15.500  28.950  33.320  1.00108.57           C  
ANISOU   90  C1'  DC A   4    15503  13922  11828  -5333   -789   -925       C  
ATOM     91  N1   DC A   4      16.379  29.435  32.232  1.00 95.91           N  
ANISOU   91  N1   DC A   4    14016  11640  10785  -4272   -840   -991       N  
ATOM     92  C2   DC A   4      17.616  28.812  31.997  1.00 93.39           C  
ANISOU   92  C2   DC A   4    14528  10358  10599  -3835  -1050   -769       C  
ATOM     93  O2   DC A   4      17.957  27.858  32.706  1.00 99.96           O  
ANISOU   93  O2   DC A   4    16076  10747  11156  -4252  -1296   -495       O  
ATOM     94  N3   DC A   4      18.411  29.282  31.001  1.00 83.95           N  
ANISOU   94  N3   DC A   4    13316   8791   9791  -2996  -1036   -903       N  
ATOM     95  C4   DC A   4      17.994  30.322  30.256  1.00 83.31           C  
ANISOU   95  C4   DC A   4    12583   9124   9948  -2681   -902  -1122       C  
ATOM     96  N4   DC A   4      18.778  30.761  29.263  1.00 74.59           N  
ANISOU   96  N4   DC A   4    11530   7720   9091  -2064   -919  -1196       N  
ATOM     97  C5   DC A   4      16.746  30.970  30.489  1.00 83.41           C  
ANISOU   97  C5   DC A   4    11845   9927   9918  -3011   -812  -1327       C  
ATOM     98  C6   DC A   4      15.980  30.499  31.476  1.00 88.50           C  
ANISOU   98  C6   DC A   4    12361  11077  10187  -3761   -745  -1314       C  
ATOM     99  P    DA A   5      14.500  28.846  37.304  1.00153.07           P  
ANISOU   99  P    DA A   5    20372  21834  15955  -7694   -340   -901       P  
ATOM    100  OP1  DA A   5      13.184  28.753  37.985  1.00157.79           O  
ANISOU  100  OP1  DA A   5    20238  23909  15807  -8937   -110  -1190       O  
ATOM    101  OP2  DA A   5      15.278  30.120  37.343  1.00135.98           O  
ANISOU  101  OP2  DA A   5    17637  19565  14465  -6399   -134  -1216       O  
ATOM    102  O5'  DA A   5      15.457  27.645  37.790  1.00152.84           O  
ANISOU  102  O5'  DA A   5    21772  20643  15656  -8141   -807   -184       O  
ATOM    103  C5'  DA A   5      16.443  27.034  36.933  1.00144.05           C  
ANISOU  103  C5'  DA A   5    21653  18090  14988  -7404  -1236    108       C  
ATOM    104  C4'  DA A   5      17.879  27.308  37.372  1.00135.14           C  
ANISOU  104  C4'  DA A   5    20869  16205  14274  -6485  -1337    223       C  
ATOM    105  O4'  DA A   5      18.610  27.923  36.274  1.00127.15           O  
ANISOU  105  O4'  DA A   5    19632  14709  13971  -5182  -1237    -42       O  
ATOM    106  C3'  DA A   5      18.061  28.222  38.586  1.00132.57           C  
ANISOU  106  C3'  DA A   5    19860  16636  13874  -6460   -971     88       C  
ATOM    107  O3'  DA A   5      18.999  27.577  39.482  1.00137.10           O  
ANISOU  107  O3'  DA A   5    21336  16482  14273  -6644  -1371    525       O  
ATOM    108  C2'  DA A   5      18.428  29.567  37.949  1.00123.24           C  
ANISOU  108  C2'  DA A   5    17804  15628  13395  -5189   -603   -366       C  
ATOM    109  C1'  DA A   5      19.174  29.162  36.677  1.00117.40           C  
ANISOU  109  C1'  DA A   5    17665  13843  13100  -4418   -877   -282       C  
ATOM    110  N9   DA A   5      19.132  30.118  35.551  1.00103.89           N  
ANISOU  110  N9   DA A   5    15321  12272  11882  -3596   -661   -629       N  
ATOM    111  C8   DA A   5      18.278  31.184  35.285  1.00101.45           C  
ANISOU  111  C8   DA A   5    14063  12764  11720  -3458   -400  -1014       C  
ATOM    112  N7   DA A   5      18.536  31.858  34.160  1.00 87.05           N  
ANISOU  112  N7   DA A   5    12038  10705  10332  -2722   -418  -1174       N  
ATOM    113  C5   DA A   5      19.640  31.185  33.664  1.00 79.61           C  
ANISOU  113  C5   DA A   5    11853   8906   9489  -2377   -590   -938       C  
ATOM    114  C6   DA A   5      20.401  31.389  32.512  1.00 75.23           C  
ANISOU  114  C6   DA A   5    11452   7910   9224  -1732   -651   -995       C  
ATOM    115  N6   DA A   5      20.142  32.348  31.617  1.00 56.86           N  
ANISOU  115  N6   DA A   5     8657   5822   7127  -1413   -605  -1173       N  
ATOM    116  N1   DA A   5      21.430  30.528  32.309  1.00 87.42           N  
ANISOU  116  N1   DA A   5    13670   8784  10763  -1473   -836   -903       N  
ATOM    117  C2   DA A   5      21.679  29.540  33.204  1.00 94.95           C  
ANISOU  117  C2   DA A   5    15226   9348  11502  -1790  -1069   -703       C  
ATOM    118  N3   DA A   5      21.032  29.233  34.337  1.00 91.78           N  
ANISOU  118  N3   DA A   5    14898   9196  10777  -2524  -1099   -498       N  
ATOM    119  C4   DA A   5      20.014  30.109  34.495  1.00 95.10           C  
ANISOU  119  C4   DA A   5    14515  10468  11151  -2810   -781   -653       C  
ATOM    120  P    DG A   6      20.458  28.029  39.982  1.00134.00           P  
ANISOU  120  P    DG A   6    21099  15485  14328  -5648  -1435    569       P  
ATOM    121  OP1  DG A   6      20.616  27.395  41.295  1.00134.77           O  
ANISOU  121  OP1  DG A   6    21853  15496  13857  -6571  -1774    998       O  
ATOM    122  OP2  DG A   6      20.717  29.488  39.851  1.00118.65           O  
ANISOU  122  OP2  DG A   6    18090  14110  12883  -4695   -888    128       O  
ATOM    123  O5'  DG A   6      21.390  27.185  38.993  1.00134.77           O  
ANISOU  123  O5'  DG A   6    22121  14251  14835  -4889  -1990    671       O  
ATOM    124  C5'  DG A   6      22.776  27.077  39.257  1.00129.45           C  
ANISOU  124  C5'  DG A   6    21899  12783  14502  -4063  -2312    716       C  
ATOM    125  C4'  DG A   6      23.607  27.839  38.236  1.00119.27           C  
ANISOU  125  C4'  DG A   6    20071  11391  13855  -2766  -2027    300       C  
ATOM    126  O4'  DG A   6      22.854  28.765  37.392  1.00118.26           O  
ANISOU  126  O4'  DG A   6    19055  11996  13883  -2628  -1477     11       O  
ATOM    127  C3'  DG A   6      24.685  28.724  38.832  1.00113.26           C  
ANISOU  127  C3'  DG A   6    18890  10753  13391  -2033  -1811    196       C  
ATOM    128  O3'  DG A   6      25.849  28.439  38.112  1.00117.28           O  
ANISOU  128  O3'  DG A   6    19667  10615  14281  -1085  -2081    -33       O  
ATOM    129  C2'  DG A   6      24.235  30.139  38.521  1.00106.84           C  
ANISOU  129  C2'  DG A   6    16997  10828  12770  -1788  -1153    -76       C  
ATOM    130  C1'  DG A   6      23.682  29.895  37.130  1.00105.39           C  
ANISOU  130  C1'  DG A   6    16798  10558  12685  -1709  -1149   -243       C  
ATOM    131  N9   DG A   6      22.941  31.022  36.556  1.00 91.44           N  
ANISOU  131  N9   DG A   6    14174   9500  11068  -1610   -727   -489       N  
ATOM    132  C8   DG A   6      21.829  31.604  37.099  1.00 91.65           C  
ANISOU  132  C8   DG A   6    13592  10323  10907  -2130   -477   -589       C  
ATOM    133  N7   DG A   6      21.345  32.595  36.393  1.00 88.82           N  
ANISOU  133  N7   DG A   6    12567  10378  10804  -1799   -291   -879       N  
ATOM    134  C5   DG A   6      22.184  32.684  35.302  1.00 83.80           C  
ANISOU  134  C5   DG A   6    12150   9222  10467  -1161   -379   -885       C  
ATOM    135  C6   DG A   6      22.135  33.585  34.204  1.00 86.82           C  
ANISOU  135  C6   DG A   6    12154   9706  11126   -731   -343  -1067       C  
ATOM    136  O6   DG A   6      21.334  34.509  33.951  1.00 69.70           O  
ANISOU  136  O6   DG A   6     9426   7971   9088   -702   -324  -1271       O  
ATOM    137  N1   DG A   6      23.173  33.334  33.322  1.00 86.59           N  
ANISOU  137  N1   DG A   6    12479   9222  11198   -308   -418  -1038       N  
ATOM    138  C2   DG A   6      24.103  32.344  33.480  1.00 83.91           C  
ANISOU  138  C2   DG A   6    12701   8395  10787   -155   -550   -972       C  
ATOM    139  N2   DG A   6      24.992  32.282  32.496  1.00 80.31           N  
ANISOU  139  N2   DG A   6    12348   7757  10410    291   -582  -1130       N  
ATOM    140  N3   DG A   6      24.166  31.496  34.500  1.00 90.95           N  
ANISOU  140  N3   DG A   6    14021   9026  11511   -433   -708   -809       N  
ATOM    141  C4   DG A   6      23.172  31.723  35.386  1.00 84.10           C  
ANISOU  141  C4   DG A   6    12889   8606  10460  -1013   -595   -712       C  
ATOM    142  P    DA A   7      27.295  28.653  38.744  1.00119.02           P  
ANISOU  142  P    DA A   7    19925  10548  14747   -334  -2246   -110       P  
ATOM    143  OP1  DA A   7      27.801  27.294  39.087  1.00118.02           O  
ANISOU  143  OP1  DA A   7    20864   9430  14550   -327  -3111      6       O  
ATOM    144  OP2  DA A   7      27.208  29.765  39.727  1.00103.90           O  
ANISOU  144  OP2  DA A   7    17378   9329  12771   -532  -1777     13       O  
ATOM    145  O5'  DA A   7      28.157  29.177  37.513  1.00103.83           O  
ANISOU  145  O5'  DA A   7    17489   8749  13213    654  -2005   -594       O  
ATOM    146  C5'  DA A   7      28.220  28.374  36.370  1.00103.53           C  
ANISOU  146  C5'  DA A   7    17787   8305  13245    945  -2289   -883       C  
ATOM    147  C4'  DA A   7      28.754  29.249  35.286  1.00 98.33           C  
ANISOU  147  C4'  DA A   7    16391   8190  12780   1535  -1829  -1276       C  
ATOM    148  O4'  DA A   7      27.832  30.331  35.016  1.00 97.21           O  
ANISOU  148  O4'  DA A   7    15647   8701  12588   1109  -1295  -1111       O  
ATOM    149  C3'  DA A   7      30.054  29.894  35.707  1.00 95.99           C  
ANISOU  149  C3'  DA A   7    15688   8135  12648   2160  -1714  -1463       C  
ATOM    150  O3'  DA A   7      30.951  29.614  34.645  1.00104.83           O  
ANISOU  150  O3'  DA A   7    16656   9318  13856   2826  -1792  -2029       O  
ATOM    151  C2'  DA A   7      29.750  31.387  35.932  1.00 83.88           C  
ANISOU  151  C2'  DA A   7    13434   7319  11118   1917  -1129  -1256       C  
ATOM    152  C1'  DA A   7      28.506  31.576  35.097  1.00 87.13           C  
ANISOU  152  C1'  DA A   7    13723   7938  11442   1448   -931  -1183       C  
ATOM    153  N9   DA A   7      27.454  32.408  35.629  1.00 83.19           N  
ANISOU  153  N9   DA A   7    12877   7835  10895    941   -670   -933       N  
ATOM    154  C8   DA A   7      26.643  32.162  36.692  1.00 86.35           C  
ANISOU  154  C8   DA A   7    13421   8265  11124    379   -713   -693       C  
ATOM    155  N7   DA A   7      25.756  33.113  36.878  1.00 89.63           N  
ANISOU  155  N7   DA A   7    13284   9238  11534    105   -437   -700       N  
ATOM    156  C5   DA A   7      25.993  34.029  35.854  1.00 80.13           C  
ANISOU  156  C5   DA A   7    11684   8217  10543    504   -303   -869       C  
ATOM    157  C6   DA A   7      25.391  35.264  35.456  1.00 78.48           C  
ANISOU  157  C6   DA A   7    10928   8417  10473    531   -188   -976       C  
ATOM    158  N6   DA A   7      24.361  35.854  36.063  1.00 69.52           N  
ANISOU  158  N6   DA A   7     9380   7694   9339    281   -134  -1072       N  
ATOM    159  N1   DA A   7      25.878  35.893  34.371  1.00 69.30           N  
ANISOU  159  N1   DA A   7     9657   7255   9420    811   -212  -1037       N  
ATOM    160  C2   DA A   7      26.901  35.299  33.742  1.00 81.89           C  
ANISOU  160  C2   DA A   7    11527   8640  10948   1049   -226  -1083       C  
ATOM    161  N3   DA A   7      27.551  34.146  34.005  1.00 73.75           N  
ANISOU  161  N3   DA A   7    10897   7280   9843   1201   -317  -1134       N  
ATOM    162  C4   DA A   7      27.033  33.572  35.081  1.00 75.31           C  
ANISOU  162  C4   DA A   7    11328   7304   9980    921   -402   -978       C  
ATOM    163  P    DA A   8      32.495  29.992  34.837  1.00105.93           P  
ANISOU  163  P    DA A   8    16351   9783  14114   3566  -1771  -2436       P  
ATOM    164  OP1  DA A   8      33.371  29.118  34.018  1.00 91.11           O  
ANISOU  164  OP1  DA A   8    14523   7801  12292   4294  -2131  -3178       O  
ATOM    165  OP2  DA A   8      32.625  30.185  36.291  1.00 92.10           O  
ANISOU  165  OP2  DA A   8    14775   7805  12414   3428  -1897  -2030       O  
ATOM    166  O5'  DA A   8      32.582  31.456  34.232  1.00102.18           O  
ANISOU  166  O5'  DA A   8    15065  10219  13540   3376  -1102  -2395       O  
ATOM    167  C5'  DA A   8      32.139  31.588  32.929  1.00101.33           C  
ANISOU  167  C5'  DA A   8    14780  10426  13293   3185   -891  -2558       C  
ATOM    168  C4'  DA A   8      31.958  33.040  32.752  1.00 97.28           C  
ANISOU  168  C4'  DA A   8    13751  10515  12695   2802   -459  -2268       C  
ATOM    169  O4'  DA A   8      30.978  33.521  33.700  1.00101.10           O  
ANISOU  169  O4'  DA A   8    14343  10783  13288   2395   -419  -1759       O  
ATOM    170  C3'  DA A   8      33.241  33.771  33.066  1.00 99.18           C  
ANISOU  170  C3'  DA A   8    13527  11268  12891   3082   -310  -2424       C  
ATOM    171  O3'  DA A   8      33.688  34.269  31.829  1.00105.14           O  
ANISOU  171  O3'  DA A   8    13873  12712  13362   2950    -85  -2699       O  
ATOM    172  C2'  DA A   8      32.801  34.808  34.116  1.00100.52           C  
ANISOU  172  C2'  DA A   8    13618  11402  13175   2769   -190  -1898       C  
ATOM    173  C1'  DA A   8      31.312  34.890  33.841  1.00 94.97           C  
ANISOU  173  C1'  DA A   8    13106  10477  12503   2303   -180  -1611       C  
ATOM    174  N9   DA A   8      30.416  35.349  34.871  1.00 80.39           N  
ANISOU  174  N9   DA A   8    11284   8485  10775   2022   -168  -1267       N  
ATOM    175  C8   DA A   8      30.219  34.727  36.062  1.00 88.72           C  
ANISOU  175  C8   DA A   8    12621   9219  11870   1981   -294  -1131       C  
ATOM    176  N7   DA A   8      29.324  35.308  36.826  1.00 75.84           N  
ANISOU  176  N7   DA A   8    10846   7714  10256   1639   -205   -927       N  
ATOM    177  C5   DA A   8      28.896  36.360  36.056  1.00 62.00           C  
ANISOU  177  C5   DA A   8     8734   6263   8562   1568   -100   -958       C  
ATOM    178  C6   DA A   8      27.930  37.336  36.335  1.00 59.93           C  
ANISOU  178  C6   DA A   8     8150   6232   8388   1371    -81   -931       C  
ATOM    179  N6   DA A   8      27.233  37.374  37.499  1.00 43.74           N  
ANISOU  179  N6   DA A   8     5976   4323   6320   1166    -37   -927       N  
ATOM    180  N1   DA A   8      27.734  38.277  35.394  1.00 57.10           N  
ANISOU  180  N1   DA A   8     7597   5993   8103   1381   -173   -965       N  
ATOM    181  C2   DA A   8      28.434  38.190  34.241  1.00 71.64           C  
ANISOU  181  C2   DA A   8     9552   7837   9833   1423   -187   -974       C  
ATOM    182  N3   DA A   8      29.376  37.319  33.869  1.00 73.55           N  
ANISOU  182  N3   DA A   8     9966   8048   9931   1584    -99  -1081       N  
ATOM    183  C4   DA A   8      29.562  36.415  34.849  1.00 69.91           C  
ANISOU  183  C4   DA A   8     9706   7354   9503   1728    -93  -1093       C  
ATOM    184  P    DT A   9      34.905  35.294  31.822  1.00108.46           P  
ANISOU  184  P    DT A   9    13723  13931  13555   2916    140  -2809       P  
ATOM    185  OP1  DT A   9      35.520  35.484  30.495  1.00 92.54           O  
ANISOU  185  OP1  DT A   9    11301  12769  11093   2702    331  -3228       O  
ATOM    186  OP2  DT A   9      35.765  34.900  32.967  1.00114.82           O  
ANISOU  186  OP2  DT A   9    14498  14567  14560   3469    -11  -2974       O  
ATOM    187  O5'  DT A   9      34.075  36.607  32.114  1.00 87.45           O  
ANISOU  187  O5'  DT A   9    11111  11170  10945   2341    210  -2147       O  
ATOM    188  C5'  DT A   9      33.310  37.144  31.079  1.00 85.66           C  
ANISOU  188  C5'  DT A   9    10933  11063  10550   1825    221  -1960       C  
ATOM    189  C4'  DT A   9      32.832  38.474  31.593  1.00 85.34           C  
ANISOU  189  C4'  DT A   9    10903  10899  10625   1489    122  -1466       C  
ATOM    190  O4'  DT A   9      32.221  38.264  32.897  1.00 77.58           O  
ANISOU  190  O4'  DT A   9    10068   9392  10017   1753     62  -1304       O  
ATOM    191  C3'  DT A   9      33.936  39.506  31.834  1.00 84.00           C  
ANISOU  191  C3'  DT A   9    10462  11210  10243   1317    158  -1380       C  
ATOM    192  O3'  DT A   9      33.737  40.599  30.979  1.00 92.85           O  
ANISOU  192  O3'  DT A   9    11641  12540  11096    687    -19  -1100       O  
ATOM    193  C2'  DT A   9      33.734  39.906  33.296  1.00 85.50           C  
ANISOU  193  C2'  DT A   9    10705  10983  10796   1568     83  -1143       C  
ATOM    194  C1'  DT A   9      32.289  39.522  33.523  1.00 74.77           C  
ANISOU  194  C1'  DT A   9     9594   9079   9737   1613    -21  -1036       C  
ATOM    195  N1   DT A   9      31.767  39.279  34.883  1.00 67.09           N  
ANISOU  195  N1   DT A   9     8688   7752   9053   1840    -25   -960       N  
ATOM    196  C2   DT A   9      30.660  40.002  35.265  1.00 72.55           C  
ANISOU  196  C2   DT A   9     9355   8279   9934   1702   -171   -827       C  
ATOM    197  O2   DT A   9      30.118  40.852  34.562  1.00 64.94           O  
ANISOU  197  O2   DT A   9     8375   7315   8985   1493   -395   -754       O  
ATOM    198  N3   DT A   9      30.209  39.696  36.518  1.00 65.57           N  
ANISOU  198  N3   DT A   9     8459   7264   9192   1807   -113   -832       N  
ATOM    199  C4   DT A   9      30.724  38.782  37.402  1.00 60.24           C  
ANISOU  199  C4   DT A   9     7920   6485   8483   1958     -5   -840       C  
ATOM    200  O4   DT A   9      30.223  38.580  38.507  1.00 56.78           O  
ANISOU  200  O4   DT A   9     7506   5993   8076   1875     16   -797       O  
ATOM    201  C5   DT A   9      31.868  38.081  36.953  1.00 65.42           C  
ANISOU  201  C5   DT A   9     8678   7151   9028   2194     20   -957       C  
ATOM    202  C7   DT A   9      32.460  37.065  37.877  1.00 64.62           C  
ANISOU  202  C7   DT A   9     8814   6802   8938   2442    -57   -998       C  
ATOM    203  C6   DT A   9      32.328  38.344  35.720  1.00 72.50           C  
ANISOU  203  C6   DT A   9     9457   8307   9781   2155     47  -1071       C  
ATOM    204  P    DC A  10      34.777  41.803  30.848  1.00 96.76           P  
ANISOU  204  P    DC A  10    11989  13590  11186    159   -100   -909       P  
ATOM    205  OP1  DC A  10      34.863  42.190  29.403  1.00 83.34           O  
ANISOU  205  OP1  DC A  10    10353  12389   8923   -610   -202   -839       O  
ATOM    206  OP2  DC A  10      35.976  41.396  31.641  1.00 82.82           O  
ANISOU  206  OP2  DC A  10     9857  12219   9393    564    177  -1213       O  
ATOM    207  O5'  DC A  10      33.985  42.933  31.624  1.00 88.82           O  
ANISOU  207  O5'  DC A  10    11273  11921  10555    118   -514   -468       O  
ATOM    208  C5'  DC A  10      32.581  42.845  31.785  1.00 85.77           C  
ANISOU  208  C5'  DC A  10    11098  10897  10592    345   -727   -400       C  
ATOM    209  C4'  DC A  10      32.143  44.163  32.384  1.00 90.75           C  
ANISOU  209  C4'  DC A  10    11898  11113  11468    286  -1217   -135       C  
ATOM    210  O4'  DC A  10      31.514  43.984  33.691  1.00 90.53           O  
ANISOU  210  O4'  DC A  10    11741  10748  11907    843  -1145   -277       O  
ATOM    211  C3'  DC A  10      33.294  45.098  32.688  1.00 89.76           C  
ANISOU  211  C3'  DC A  10    11775  11246  11082    -24  -1338     62       C  
ATOM    212  O3'  DC A  10      32.840  46.376  32.794  1.00 94.98           O  
ANISOU  212  O3'  DC A  10    12755  11447  11884   -219  -1994    318       O  
ATOM    213  C2'  DC A  10      33.704  44.671  34.081  1.00 88.52           C  
ANISOU  213  C2'  DC A  10    11351  11088  11195    543   -991   -112       C  
ATOM    214  C1'  DC A  10      32.326  44.511  34.727  1.00 80.81           C  
ANISOU  214  C1'  DC A  10    10408   9586  10710    971  -1109   -225       C  
ATOM    215  N1   DC A  10      32.319  43.576  35.905  1.00 71.82           N  
ANISOU  215  N1   DC A  10     9072   8440   9778   1437   -710   -421       N  
ATOM    216  C2   DC A  10      31.438  43.794  36.961  1.00 73.93           C  
ANISOU  216  C2   DC A  10     9258   8468  10365   1698   -794   -527       C  
ATOM    217  O2   DC A  10      30.670  44.762  36.921  1.00 75.98           O  
ANISOU  217  O2   DC A  10     9544   8513  10813   1696  -1216   -563       O  
ATOM    218  N3   DC A  10      31.459  42.945  38.020  1.00 69.98           N  
ANISOU  218  N3   DC A  10     8654   8008   9926   1927   -476   -633       N  
ATOM    219  C4   DC A  10      32.313  41.928  38.017  1.00 70.02           C  
ANISOU  219  C4   DC A  10     8707   8124   9775   2008   -206   -635       C  
ATOM    220  N4   DC A  10      32.299  41.107  39.056  1.00 67.63           N  
ANISOU  220  N4   DC A  10     8440   7741   9516   2166    -52   -677       N  
ATOM    221  C5   DC A  10      33.214  41.664  36.948  1.00 72.62           C  
ANISOU  221  C5   DC A  10     9045   8689   9859   1918   -138   -654       C  
ATOM    222  C6   DC A  10      33.188  42.510  35.926  1.00 68.00           C  
ANISOU  222  C6   DC A  10     8490   8220   9124   1578   -336   -545       C  
ATOM    223  P    DG A  11      33.972  47.489  32.717  1.00108.12           P  
ANISOU  223  P    DG A  11    14614  13344  13121   -860  -2311    649       P  
ATOM    224  OP1  DG A  11      33.695  48.040  31.379  1.00108.70           O  
ANISOU  224  OP1  DG A  11    15123  13357  12822  -1617  -2847    946       O  
ATOM    225  OP2  DG A  11      35.330  46.954  33.019  1.00 79.79           O  
ANISOU  225  OP2  DG A  11    10618  10516   9184   -914  -1701    517       O  
ATOM    226  O5'  DG A  11      33.567  48.599  33.826  1.00104.50           O  
ANISOU  226  O5'  DG A  11    14365  12217  13123   -524  -2888    715       O  
ATOM    227  C5'  DG A  11      32.197  49.061  33.994  1.00 98.07           C  
ANISOU  227  C5'  DG A  11    13734  10696  12832    -98  -3472    571       C  
ATOM    228  C4'  DG A  11      31.973  49.515  35.431  1.00 90.16           C  
ANISOU  228  C4'  DG A  11    12561   9411  12284    524  -3571    316       C  
ATOM    229  O4'  DG A  11      32.091  48.400  36.365  1.00 86.50           O  
ANISOU  229  O4'  DG A  11    11591   9336  11939    991  -2732     41       O  
ATOM    230  C3'  DG A  11      33.012  50.507  35.918  1.00 84.78           C  
ANISOU  230  C3'  DG A  11    12114   8685  11413    213  -3886    575       C  
ATOM    231  O3'  DG A  11      32.369  51.505  36.654  1.00 83.23           O  
ANISOU  231  O3'  DG A  11    12089   7876  11660    640  -4595    369       O  
ATOM    232  C2'  DG A  11      33.986  49.685  36.766  1.00 69.54           C  
ANISOU  232  C2'  DG A  11     9719   7354   9348    386  -3015    491       C  
ATOM    233  C1'  DG A  11      33.016  48.716  37.383  1.00 69.00           C  
ANISOU  233  C1'  DG A  11     9274   7263   9678   1061  -2574     85       C  
ATOM    234  N9   DG A  11      33.596  47.467  37.805  1.00 65.94           N  
ANISOU  234  N9   DG A  11     8541   7340   9174   1233  -1793    -10       N  
ATOM    235  C8   DG A  11      34.589  46.740  37.191  1.00 64.22           C  
ANISOU  235  C8   DG A  11     8218   7609   8572    973  -1382     75       C  
ATOM    236  N7   DG A  11      34.865  45.616  37.835  1.00 63.80           N  
ANISOU  236  N7   DG A  11     7907   7751   8582   1352   -874   -120       N  
ATOM    237  C5   DG A  11      34.010  45.631  38.931  1.00 49.24           C  
ANISOU  237  C5   DG A  11     6019   5591   7097   1725   -902   -255       C  
ATOM    238  C6   DG A  11      33.911  44.685  39.961  1.00 67.89           C  
ANISOU  238  C6   DG A  11     8240   7983   9573   2047   -555   -402       C  
ATOM    239  O6   DG A  11      34.585  43.629  40.074  1.00 56.47           O  
ANISOU  239  O6   DG A  11     6752   6694   8008   2168   -257   -437       O  
ATOM    240  N1   DG A  11      32.938  45.072  40.883  1.00 65.87           N  
ANISOU  240  N1   DG A  11     7905   7567   9557   2210   -669   -562       N  
ATOM    241  C2   DG A  11      32.178  46.219  40.806  1.00 73.86           C  
ANISOU  241  C2   DG A  11     8922   8378  10763   2240  -1117   -684       C  
ATOM    242  N2   DG A  11      31.307  46.406  41.808  1.00 73.38           N  
ANISOU  242  N2   DG A  11     8631   8360  10890   2469  -1142  -1014       N  
ATOM    243  N3   DG A  11      32.258  47.130  39.834  1.00 66.49           N  
ANISOU  243  N3   DG A  11     8218   7234   9810   2037  -1588   -537       N  
ATOM    244  C4   DG A  11      33.211  46.753  38.933  1.00 62.11           C  
ANISOU  244  C4   DG A  11     7784   6883   8931   1703  -1415   -266       C  
ATOM    245  P    DA A  12      33.281  52.712  37.140  1.00 89.01           P  
ANISOU  245  P    DA A  12    13217   8359  12244    309  -5162    642       P  
ATOM    246  OP1  DA A  12      32.615  54.007  36.942  1.00 74.86           O  
ANISOU  246  OP1  DA A  12    12032   5686  10726    355  -6429    627       O  
ATOM    247  OP2  DA A  12      34.634  52.456  36.625  1.00 86.10           O  
ANISOU  247  OP2  DA A  12    12872   8626  11217   -500  -4718   1087       O  
ATOM    248  O5'  DA A  12      33.454  52.382  38.673  1.00 84.88           O  
ANISOU  248  O5'  DA A  12    12172   8083  11995    958  -4570    271       O  
ATOM    249  C5'  DA A  12      32.402  52.162  39.603  1.00 78.65           C  
ANISOU  249  C5'  DA A  12    10977   7206  11701   1756  -4459   -317       C  
ATOM    250  C4'  DA A  12      33.006  51.476  40.809  1.00 70.96           C  
ANISOU  250  C4'  DA A  12     9549   6739  10672   1975  -3637   -429       C  
ATOM    251  O4'  DA A  12      33.699  50.231  40.454  1.00 54.02           O  
ANISOU  251  O4'  DA A  12     7196   5131   8198   1718  -2824   -191       O  
ATOM    252  C3'  DA A  12      34.099  52.256  41.497  1.00 64.57           C  
ANISOU  252  C3'  DA A  12     8919   5898   9715   1782  -3811   -217       C  
ATOM    253  O3'  DA A  12      33.533  52.891  42.637  1.00 66.84           O  
ANISOU  253  O3'  DA A  12     9076   5954  10366   2332  -4120   -690       O  
ATOM    254  C2'  DA A  12      35.149  51.182  41.844  1.00 64.89           C  
ANISOU  254  C2'  DA A  12     8625   6584   9445   1635  -2906    -30       C  
ATOM    255  C1'  DA A  12      34.374  49.877  41.585  1.00 52.05           C  
ANISOU  255  C1'  DA A  12     6689   5180   7908   1889  -2353   -239       C  
ATOM    256  N9   DA A  12      35.184  48.746  41.228  1.00 54.72           N  
ANISOU  256  N9   DA A  12     6867   5970   7953   1717  -1738    -70       N  
ATOM    257  C8   DA A  12      36.050  48.679  40.184  1.00 58.06           C  
ANISOU  257  C8   DA A  12     7383   6679   7998   1244  -1698    192       C  
ATOM    258  N7   DA A  12      36.716  47.548  40.085  1.00 63.15           N  
ANISOU  258  N7   DA A  12     7763   7772   8461   1313  -1149    129       N  
ATOM    259  C5   DA A  12      36.236  46.853  41.162  1.00 57.72           C  
ANISOU  259  C5   DA A  12     6926   6952   8053   1800   -886    -75       C  
ATOM    260  C6   DA A  12      36.599  45.579  41.590  1.00 45.62           C  
ANISOU  260  C6   DA A  12     5227   5605   6501   2072   -465   -195       C  
ATOM    261  N6   DA A  12      37.471  44.937  40.843  1.00 61.64           N  
ANISOU  261  N6   DA A  12     7138   7998   8284   2010   -278   -237       N  
ATOM    262  N1   DA A  12      36.019  45.069  42.700  1.00 47.22           N  
ANISOU  262  N1   DA A  12     5409   5637   6894   2344   -340   -304       N  
ATOM    263  C2   DA A  12      35.103  45.909  43.310  1.00 69.81           C  
ANISOU  263  C2   DA A  12     8268   8307   9947   2377   -552   -402       C  
ATOM    264  N3   DA A  12      34.681  47.167  43.004  1.00 52.86           N  
ANISOU  264  N3   DA A  12     6202   5965   7915   2301   -984   -430       N  
ATOM    265  C4   DA A  12      35.297  47.566  41.889  1.00 51.09           C  
ANISOU  265  C4   DA A  12     6143   5763   7506   1988  -1174   -200       C  
ATOM    266  P    DT A  13      34.346  54.092  43.288  1.00 79.64           P  
ANISOU  266  P    DT A  13    11043   7267  11950   2205  -4680   -564       P  
ATOM    267  OP1  DT A  13      33.452  55.276  43.489  1.00 67.75           O  
ANISOU  267  OP1  DT A  13     9800   5077  10866   2660  -5720  -1028       O  
ATOM    268  OP2  DT A  13      35.570  54.242  42.449  1.00 88.07           O  
ANISOU  268  OP2  DT A  13    12492   8448  12524   1379  -4714    115       O  
ATOM    269  O5'  DT A  13      34.867  53.363  44.635  1.00 70.03           O  
ANISOU  269  O5'  DT A  13     9313   6633  10663   2432  -3814   -707       O  
ATOM    270  C5'  DT A  13      33.943  52.683  45.522  1.00 73.40           C  
ANISOU  270  C5'  DT A  13     9211   7378  11298   2947  -3348  -1254       C  
ATOM    271  C4'  DT A  13      34.429  51.373  46.168  1.00 58.85           C  
ANISOU  271  C4'  DT A  13     7021   6117   9221   2868  -2420  -1120       C  
ATOM    272  O4'  DT A  13      35.261  50.570  45.323  1.00 38.66           O  
ANISOU  272  O4'  DT A  13     4565   3729   6395   2507  -2055   -643       O  
ATOM    273  C3'  DT A  13      35.437  51.422  47.271  1.00 63.31           C  
ANISOU  273  C3'  DT A  13     7530   6898   9625   2811  -2169   -991       C  
ATOM    274  O3'  DT A  13      34.863  51.862  48.478  1.00 69.05           O  
ANISOU  274  O3'  DT A  13     8026   7715  10493   3135  -2248  -1491       O  
ATOM    275  C2'  DT A  13      35.889  49.963  47.400  1.00 56.81           C  
ANISOU  275  C2'  DT A  13     6528   6474   8584   2698  -1455   -767       C  
ATOM    276  C1'  DT A  13      35.573  49.379  46.040  1.00 45.04           C  
ANISOU  276  C1'  DT A  13     5120   4920   7074   2572  -1406   -627       C  
ATOM    277  N1   DT A  13      36.680  48.650  45.332  1.00 34.28           N  
ANISOU  277  N1   DT A  13     3803   3770   5452   2333  -1121   -273       N  
ATOM    278  C2   DT A  13      37.041  47.330  45.593  1.00 62.36           C  
ANISOU  278  C2   DT A  13     7232   7557   8906   2432   -666   -246       C  
ATOM    279  O2   DT A  13      36.483  46.712  46.504  1.00 66.33           O  
ANISOU  279  O2   DT A  13     7664   8073   9465   2578   -474   -388       O  
ATOM    280  N3   DT A  13      38.090  46.788  44.780  1.00 40.22           N  
ANISOU  280  N3   DT A  13     4390   5006   5885   2316   -519    -96       N  
ATOM    281  C4   DT A  13      38.706  47.514  43.758  1.00 56.55           C  
ANISOU  281  C4   DT A  13     6500   7244   7741   1954   -711     57       C  
ATOM    282  O4   DT A  13      39.596  47.108  43.028  1.00 49.51           O  
ANISOU  282  O4   DT A  13     5457   6774   6579   1792   -556     74       O  
ATOM    283  C5   DT A  13      38.219  48.871  43.540  1.00 51.69           C  
ANISOU  283  C5   DT A  13     6141   6309   7191   1706  -1211    158       C  
ATOM    284  C7   DT A  13      38.819  49.764  42.491  1.00 44.21           C  
ANISOU  284  C7   DT A  13     5408   5471   5921   1098  -1573    432       C  
ATOM    285  C6   DT A  13      37.262  49.329  44.313  1.00 38.06           C  
ANISOU  285  C6   DT A  13     4474   4220   5768   1982  -1420    -32       C  
ATOM    286  P    DT A  14      35.952  52.097  49.636  1.00 78.27           P  
ANISOU  286  P    DT A  14     9204   9047  11486   3042  -2097  -1336       P  
ATOM    287  OP1  DT A  14      35.018  52.930  50.427  1.00 44.05           O  
ANISOU  287  OP1  DT A  14     4682   4684   7371   3429  -2457  -2016       O  
ATOM    288  OP2  DT A  14      37.340  52.526  49.251  1.00 64.98           O  
ANISOU  288  OP2  DT A  14     7840   7231   9620   2690  -2261   -795       O  
ATOM    289  O5'  DT A  14      36.276  50.616  50.089  1.00 37.65           O  
ANISOU  289  O5'  DT A  14     3857   4347   6101   2903  -1359  -1123       O  
ATOM    290  C5'  DT A  14      35.307  50.044  50.950  1.00 57.17           C  
ANISOU  290  C5'  DT A  14     6023   7172   8528   2985  -1056  -1521       C  
ATOM    291  C4'  DT A  14      35.629  48.608  51.256  1.00 51.74           C  
ANISOU  291  C4'  DT A  14     5352   6721   7585   2749   -558  -1211       C  
ATOM    292  O4'  DT A  14      36.329  48.059  50.099  1.00 40.15           O  
ANISOU  292  O4'  DT A  14     4094   5034   6128   2701   -530   -801       O  
ATOM    293  C3'  DT A  14      36.632  48.450  52.404  1.00 62.58           C  
ANISOU  293  C3'  DT A  14     6788   8237   8751   2636   -427   -997       C  
ATOM    294  O3'  DT A  14      36.664  47.099  52.982  1.00 39.24           O  
ANISOU  294  O3'  DT A  14     3920   5451   5540   2399   -126   -800       O  
ATOM    295  C2'  DT A  14      37.935  48.676  51.639  1.00 55.19           C  
ANISOU  295  C2'  DT A  14     6041   7071   7859   2660   -571   -594       C  
ATOM    296  C1'  DT A  14      37.617  47.769  50.469  1.00 33.96           C  
ANISOU  296  C1'  DT A  14     3404   4294   5203   2651   -445   -485       C  
ATOM    297  N1   DT A  14      38.500  47.948  49.356  1.00 47.16           N  
ANISOU  297  N1   DT A  14     5151   5901   6866   2611   -553   -248       N  
ATOM    298  C2   DT A  14      39.236  46.823  49.004  1.00 45.72           C  
ANISOU  298  C2   DT A  14     4967   5829   6574   2655   -357    -94       C  
ATOM    299  O2   DT A  14      39.153  45.723  49.540  1.00 69.67           O  
ANISOU  299  O2   DT A  14     8066   8841   9565   2739   -214    -85       O  
ATOM    300  N3   DT A  14      40.063  47.012  47.948  1.00 33.20           N  
ANISOU  300  N3   DT A  14     3323   4399   4893   2565   -408      9       N  
ATOM    301  C4   DT A  14      40.305  48.181  47.240  1.00 49.01           C  
ANISOU  301  C4   DT A  14     5366   6433   6823   2279   -657    106       C  
ATOM    302  O4   DT A  14      41.094  48.240  46.282  1.00 64.28           O  
ANISOU  302  O4   DT A  14     7215   8676   8532   2035   -660    201       O  
ATOM    303  C5   DT A  14      39.522  49.305  47.661  1.00 48.31           C  
ANISOU  303  C5   DT A  14     5438   6023   6896   2247   -981     34       C  
ATOM    304  C7   DT A  14      39.742  50.565  46.920  1.00 47.36           C  
ANISOU  304  C7   DT A  14     5546   5753   6697   1892  -1454    190       C  
ATOM    305  C6   DT A  14      38.660  49.160  48.709  1.00 51.79           C  
ANISOU  305  C6   DT A  14     5825   6353   7498   2490   -905   -208       C  
ATOM    306  P    DC A  15      37.074  46.801  54.490  1.00 71.64           P  
ANISOU  306  P    DC A  15     8076   9803   9343   2158    -25   -720       P  
ATOM    307  OP1  DC A  15      35.795  46.445  55.195  1.00 62.45           O  
ANISOU  307  OP1  DC A  15     6728   9096   7905   1805    175  -1058       O  
ATOM    308  OP2  DC A  15      37.799  48.068  54.870  1.00 46.98           O  
ANISOU  308  OP2  DC A  15     4873   6648   6328   2345   -221   -794       O  
ATOM    309  O5'  DC A  15      38.073  45.529  54.379  1.00 37.65           O  
ANISOU  309  O5'  DC A  15     4124   5236   4947   2120    -50   -230       O  
ATOM    310  C5'  DC A  15      38.553  45.281  53.110  1.00 35.88           C  
ANISOU  310  C5'  DC A  15     3946   4756   4931   2383   -116   -104       C  
ATOM    311  C4'  DC A  15      39.191  43.891  53.194  1.00 54.57           C  
ANISOU  311  C4'  DC A  15     6627   6902   7205   2412   -223    158       C  
ATOM    312  O4'  DC A  15      40.195  43.769  52.134  1.00 49.35           O  
ANISOU  312  O4'  DC A  15     5884   6154   6713   2777   -313    183       O  
ATOM    313  C3'  DC A  15      40.079  43.527  54.390  1.00 52.70           C  
ANISOU  313  C3'  DC A  15     6590   6630   6801   2361   -407    363       C  
ATOM    314  O3'  DC A  15      40.511  42.235  54.234  1.00 66.25           O  
ANISOU  314  O3'  DC A  15     8656   8003   8513   2489   -677    521       O  
ATOM    315  C2'  DC A  15      41.184  44.551  54.095  1.00 55.22           C  
ANISOU  315  C2'  DC A  15     6609   7101   7270   2652   -428    324       C  
ATOM    316  C1'  DC A  15      41.420  44.336  52.608  1.00 56.08           C  
ANISOU  316  C1'  DC A  15     6592   7168   7547   2908   -411    244       C  
ATOM    317  N1   DC A  15      41.853  45.492  51.697  1.00 43.51           N  
ANISOU  317  N1   DC A  15     4705   5807   6021   2924   -365    175       N  
ATOM    318  C2   DC A  15      42.767  45.159  50.707  1.00 44.91           C  
ANISOU  318  C2   DC A  15     4697   6181   6185   3102   -386    116       C  
ATOM    319  O2   DC A  15      43.268  43.977  50.715  1.00 76.97           O  
ANISOU  319  O2   DC A  15     8804  10176  10266   3409   -492     37       O  
ATOM    320  N3   DC A  15      43.168  46.155  49.852  1.00 46.12           N  
ANISOU  320  N3   DC A  15     4637   6626   6258   2902   -373    113       N  
ATOM    321  C4   DC A  15      42.652  47.398  49.967  1.00 60.35           C  
ANISOU  321  C4   DC A  15     6530   8324   8075   2623   -461    195       C  
ATOM    322  N4   DC A  15      43.039  48.342  49.116  1.00 70.00           N  
ANISOU  322  N4   DC A  15     7698   9732   9166   2306   -589    273       N  
ATOM    323  C5   DC A  15      41.670  47.735  50.919  1.00 43.67           C  
ANISOU  323  C5   DC A  15     4579   5934   6078   2622   -491    146       C  
ATOM    324  C6   DC A  15      41.302  46.748  51.766  1.00 57.05           C  
ANISOU  324  C6   DC A  15     6367   7541   7770   2737   -376    122       C  
ATOM    325  P    DT A  16      41.370  41.400  55.279  1.00 83.00           P  
ANISOU  325  P    DT A  16    11182   9858  10496   2493  -1107    761       P  
ATOM    326  OP1  DT A  16      40.401  40.462  55.891  1.00 80.71           O  
ANISOU  326  OP1  DT A  16    11414   9357   9897   1917  -1255    969       O  
ATOM    327  OP2  DT A  16      42.276  42.294  56.021  1.00 82.66           O  
ANISOU  327  OP2  DT A  16    10895  10076  10437   2583  -1098    776       O  
ATOM    328  O5'  DT A  16      42.320  40.593  54.315  1.00 64.79           O  
ANISOU  328  O5'  DT A  16     8898   7267   8453   3122  -1429    634       O  
ATOM    329  C5'  DT A  16      42.971  41.336  53.290  1.00 75.15           C  
ANISOU  329  C5'  DT A  16     9656   8944   9955   3501  -1198    373       C  
ATOM    330  C4'  DT A  16      44.072  40.406  52.766  1.00 84.19           C  
ANISOU  330  C4'  DT A  16    10766   9966  11257   4119  -1598    130       C  
ATOM    331  O4'  DT A  16      45.042  41.045  51.866  1.00 91.89           O  
ANISOU  331  O4'  DT A  16    11094  11530  12290   4432  -1409   -193       O  
ATOM    332  C3'  DT A  16      44.993  39.862  53.829  1.00 71.61           C  
ANISOU  332  C3'  DT A  16     9414   8137   9656   4356  -2128    201       C  
ATOM    333  O3'  DT A  16      45.546  38.607  53.339  1.00 90.06           O  
ANISOU  333  O3'  DT A  16    11937  10097  12184   4976  -2699   -100       O  
ATOM    334  C2'  DT A  16      45.930  41.081  53.976  1.00 60.13           C  
ANISOU  334  C2'  DT A  16     7354   7325   8167   4398  -1861    114       C  
ATOM    335  C1'  DT A  16      46.067  41.701  52.592  1.00 64.78           C  
ANISOU  335  C1'  DT A  16     7380   8444   8789   4474  -1465   -173       C  
ATOM    336  N1   DT A  16      45.888  43.258  52.425  1.00 68.73           N  
ANISOU  336  N1   DT A  16     7565   9392   9158   3998  -1026    -38       N  
ATOM    337  C2   DT A  16      46.548  43.857  51.374  1.00 72.63           C  
ANISOU  337  C2   DT A  16     7556  10480   9560   3978   -850   -251       C  
ATOM    338  O2   DT A  16      47.241  43.220  50.607  1.00 99.03           O  
ANISOU  338  O2   DT A  16    10577  14148  12903   4336   -926   -617       O  
ATOM    339  N3   DT A  16      46.407  45.216  51.214  1.00 58.72           N  
ANISOU  339  N3   DT A  16     5682   8967   7661   3491   -648    -74       N  
ATOM    340  C4   DT A  16      45.681  46.042  52.017  1.00 47.87           C  
ANISOU  340  C4   DT A  16     4586   7297   6305   3183   -620    180       C  
ATOM    341  O4   DT A  16      45.580  47.259  51.841  1.00 67.54           O  
ANISOU  341  O4   DT A  16     7048   9899   8713   2821   -596    284       O  
ATOM    342  C5   DT A  16      45.011  45.394  53.090  1.00 52.53           C  
ANISOU  342  C5   DT A  16     5537   7446   6976   3263   -694    281       C  
ATOM    343  C7   DT A  16      44.194  46.316  53.959  1.00 59.26           C  
ANISOU  343  C7   DT A  16     6554   8170   7794   2941   -626    389       C  
ATOM    344  C6   DT A  16      45.083  44.045  53.238  1.00 55.72           C  
ANISOU  344  C6   DT A  16     6138   7589   7445   3571   -881    232       C  
ATOM    345  P    DG A  17      46.940  38.132  53.881  1.00 97.09           P  
ANISOU  345  P    DG A  17    12759  10926  13205   5612  -3343   -347       P  
ATOM    346  OP1  DG A  17      47.190  36.701  53.578  1.00116.47           O  
ANISOU  346  OP1  DG A  17    15648  12727  15880   6241  -4147   -656       O  
ATOM    347  OP2  DG A  17      47.023  38.636  55.279  1.00 92.51           O  
ANISOU  347  OP2  DG A  17    12420  10296  12435   5163  -3398     97       O  
ATOM    348  O5'  DG A  17      47.947  39.008  52.978  1.00102.03           O  
ANISOU  348  O5'  DG A  17    12373  12534  13861   5956  -2905   -845       O  
ATOM    349  C5'  DG A  17      48.014  38.801  51.562  1.00100.94           C  
ANISOU  349  C5'  DG A  17    11791  12777  13786   6271  -2702  -1342       C  
ATOM    350  C4'  DG A  17      49.396  38.467  50.982  1.00104.79           C  
ANISOU  350  C4'  DG A  17    11551  13912  14353   7044  -2967  -2124       C  
ATOM    351  O4'  DG A  17      50.002  39.704  50.527  1.00107.44           O  
ANISOU  351  O4'  DG A  17    11073  15331  14418   6685  -2365  -2232       O  
ATOM    352  C3'  DG A  17      50.475  37.862  51.856  1.00 97.19           C  
ANISOU  352  C3'  DG A  17    10590  12779  13560   7708  -3720  -2408       C  
ATOM    353  O3'  DG A  17      51.420  37.170  50.998  1.00116.85           O  
ANISOU  353  O3'  DG A  17    12436  15772  16191   8607  -4067  -3376       O  
ATOM    354  C2'  DG A  17      51.041  39.102  52.561  1.00 92.73           C  
ANISOU  354  C2'  DG A  17     9614  12847  12771   7243  -3338  -2111       C  
ATOM    355  C1'  DG A  17      50.853  40.217  51.524  1.00101.25           C  
ANISOU  355  C1'  DG A  17    10094  14804  13573   6668  -2505  -2122       C  
ATOM    356  N9   DG A  17      50.250  41.474  51.999  1.00 91.26           N  
ANISOU  356  N9   DG A  17     9018  13546  12108   5821  -2016  -1458       N  
ATOM    357  C8   DG A  17      49.410  41.670  53.062  1.00 83.95           C  
ANISOU  357  C8   DG A  17     8765  11923  11209   5428  -2045   -862       C  
ATOM    358  N7   DG A  17      49.073  42.927  53.226  1.00 89.35           N  
ANISOU  358  N7   DG A  17     9384  12850  11716   4808  -1619   -526       N  
ATOM    359  C5   DG A  17      49.756  43.605  52.232  1.00 80.48           C  
ANISOU  359  C5   DG A  17     7609  12560  10410   4685  -1344   -802       C  
ATOM    360  C6   DG A  17      49.791  44.983  51.935  1.00 78.33           C  
ANISOU  360  C6   DG A  17     7128  12750   9885   4038  -1014   -590       C  
ATOM    361  O6   DG A  17      49.208  45.898  52.508  1.00 74.99           O  
ANISOU  361  O6   DG A  17     7029  12033   9429   3592   -923   -195       O  
ATOM    362  N1   DG A  17      50.582  45.278  50.844  1.00 76.13           N  
ANISOU  362  N1   DG A  17     6222  13371   9334   3886   -851   -926       N  
ATOM    363  C2   DG A  17      51.281  44.329  50.141  1.00 96.84           C  
ANISOU  363  C2   DG A  17     8330  16514  11950   4417   -936  -1543       C  
ATOM    364  N2   DG A  17      52.013  44.790  49.115  1.00104.88           N  
ANISOU  364  N2   DG A  17     8665  18621  12562   4062   -699  -1878       N  
ATOM    365  N3   DG A  17      51.279  43.020  50.419  1.00 99.49           N  
ANISOU  365  N3   DG A  17     8824  16367  12612   5208  -1301  -1855       N  
ATOM    366  C4   DG A  17      50.477  42.728  51.471  1.00 85.44           C  
ANISOU  366  C4   DG A  17     7800  13579  11084   5252  -1518  -1388       C  
ATOM    367  P    DC A  18      52.934  36.910  51.523  1.00133.94           P  
ANISOU  367  P    DC A  18    14017  18393  18482   9430  -4697  -4041       P  
ATOM    368  OP1  DC A  18      53.718  36.017  50.645  1.00126.18           O  
ANISOU  368  OP1  DC A  18    12405  17850  17687  10483  -5173  -5201       O  
ATOM    369  OP2  DC A  18      52.871  36.630  52.978  1.00110.57           O  
ANISOU  369  OP2  DC A  18    11902  14451  15660   9383  -5348  -3442       O  
ATOM    370  O5'  DC A  18      53.502  38.402  51.378  1.00136.52           O  
ANISOU  370  O5'  DC A  18    13440  20035  18398   8748  -3832  -3944       O  
ATOM    371  C5'  DC A  18      53.861  38.924  50.104  1.00138.35           C  
ANISOU  371  C5'  DC A  18    12727  21525  18313   8554  -3205  -4480       C  
ATOM    372  C4'  DC A  18      54.819  40.083  50.281  1.00134.87           C  
ANISOU  372  C4'  DC A  18    11478  22283  17484   8059  -2796  -4502       C  
ATOM    373  O4'  DC A  18      54.040  41.170  50.813  1.00127.58           O  
ANISOU  373  O4'  DC A  18    11128  20947  16402   7075  -2345  -3494       O  
ATOM    374  C3'  DC A  18      55.988  39.837  51.242  1.00137.15           C  
ANISOU  374  C3'  DC A  18    11419  22782  17910   8688  -3392  -4876       C  
ATOM    375  O3'  DC A  18      57.252  39.798  50.527  1.00148.62           O  
ANISOU  375  O3'  DC A  18    11577  25764  19126   9113  -3364  -5967       O  
ATOM    376  C2'  DC A  18      55.865  40.964  52.264  1.00125.89           C  
ANISOU  376  C2'  DC A  18    10345  21184  16302   7843  -3110  -3965       C  
ATOM    377  C1'  DC A  18      54.888  41.926  51.627  1.00120.76           C  
ANISOU  377  C1'  DC A  18     9941  20576  15365   6833  -2355  -3352       C  
ATOM    378  N1   DC A  18      53.995  42.606  52.578  1.00113.58           N  
ANISOU  378  N1   DC A  18     9877  18786  14493   6199  -2224  -2407       N  
ATOM    379  C2   DC A  18      53.703  43.951  52.362  1.00104.00           C  
ANISOU  379  C2   DC A  18     8630  17938  12946   5266  -1688  -1939       C  
ATOM    380  O2   DC A  18      54.204  44.524  51.385  1.00103.90           O  
ANISOU  380  O2   DC A  18     7970  18942  12565   4865  -1356  -2213       O  
ATOM    381  N3   DC A  18      52.877  44.581  53.238  1.00101.72           N  
ANISOU  381  N3   DC A  18     9038  16898  12713   4800  -1617  -1242       N  
ATOM    382  C4   DC A  18      52.356  43.911  54.275  1.00 99.00           C  
ANISOU  382  C4   DC A  18     9347  15629  12640   5095  -1957   -979       C  
ATOM    383  N4   DC A  18      51.546  44.570  55.111  1.00 92.02           N  
ANISOU  383  N4   DC A  18     9012  14225  11727   4591  -1827   -421       N  
ATOM    384  C5   DC A  18      52.641  42.532  54.503  1.00102.12           C  
ANISOU  384  C5   DC A  18     9888  15605  13309   5883  -2526  -1317       C  
ATOM    385  C6   DC A  18      53.452  41.926  53.636  1.00110.00           C  
ANISOU  385  C6   DC A  18    10243  17204  14349   6481  -2687  -2041       C  
ATOM    386  P    DA A  19      58.690  40.042  51.226  1.00160.23           P  
ANISOU  386  P    DA A  19    12197  28183  20499   9455  -3681  -6480       P  
ATOM    387  OP1  DA A  19      59.758  39.569  50.309  1.00166.94           O  
ANISOU  387  OP1  DA A  19    11713  30528  21188  10161  -3778  -7888       O  
ATOM    388  OP2  DA A  19      58.635  39.510  52.603  1.00160.94           O  
ANISOU  388  OP2  DA A  19    13148  26942  21058   9980  -4490  -6054       O  
ATOM    389  O5'  DA A  19      58.766  41.631  51.368  1.00144.07           O  
ANISOU  389  O5'  DA A  19     9966  26891  17882   8087  -2895  -5715       O  
ATOM    390  C5'  DA A  19      58.284  42.442  50.305  1.00144.52           C  
ANISOU  390  C5'  DA A  19     9864  27589  17456   7081  -2127  -5457       C  
ATOM    391  C4'  DA A  19      58.615  43.882  50.593  1.00139.25           C  
ANISOU  391  C4'  DA A  19     9048  27586  16273   5910  -1690  -4843       C  
ATOM    392  O4'  DA A  19      57.530  44.506  51.329  1.00130.46           O  
ANISOU  392  O4'  DA A  19     9086  25139  15345   5354  -1609  -3724       O  
ATOM    393  C3'  DA A  19      59.893  44.005  51.413  1.00138.92           C  
ANISOU  393  C3'  DA A  19     8329  28303  16149   6185  -2002  -5222       C  
ATOM    394  O3'  DA A  19      60.875  44.676  50.642  1.00154.63           O  
ANISOU  394  O3'  DA A  19     9165  32165  17422   5494  -1593  -5749       O  
ATOM    395  C2'  DA A  19      59.497  44.748  52.677  1.00128.95           C  
ANISOU  395  C2'  DA A  19     7963  26013  15018   5702  -2082  -4185       C  
ATOM    396  C1'  DA A  19      58.088  45.269  52.389  1.00127.13           C  
ANISOU  396  C1'  DA A  19     8697  24796  14812   5001  -1711  -3330       C  
ATOM    397  N9   DA A  19      57.199  45.172  53.548  1.00120.03           N  
ANISOU  397  N9   DA A  19     8871  22395  14342   5142  -1963  -2603       N  
ATOM    398  C8   DA A  19      56.922  44.044  54.280  1.00119.56           C  
ANISOU  398  C8   DA A  19     9322  21328  14776   6003  -2504  -2659       C  
ATOM    399  N7   DA A  19      56.096  44.251  55.277  1.00113.39           N  
ANISOU  399  N7   DA A  19     9443  19484  14154   5738  -2580  -1925       N  
ATOM    400  C5   DA A  19      55.815  45.609  55.190  1.00110.66           C  
ANISOU  400  C5   DA A  19     9150  19415  13480   4794  -2087  -1439       C  
ATOM    401  C6   DA A  19      54.987  46.456  55.953  1.00105.08           C  
ANISOU  401  C6   DA A  19     9138  18032  12754   4200  -1942   -745       C  
ATOM    402  N6   DA A  19      54.307  45.972  56.983  1.00103.78           N  
ANISOU  402  N6   DA A  19     9673  16924  12836   4401  -2187   -423       N  
ATOM    403  N1   DA A  19      54.891  47.770  55.631  1.00102.93           N  
ANISOU  403  N1   DA A  19     8830  18109  12168   3385  -1618   -452       N  
ATOM    404  C2   DA A  19      55.617  48.191  54.587  1.00106.96           C  
ANISOU  404  C2   DA A  19     8674  19653  12313   3020  -1422   -741       C  
ATOM    405  N3   DA A  19      56.428  47.489  53.787  1.00108.78           N  
ANISOU  405  N3   DA A  19     8122  20777  12431   3399  -1417  -1400       N  
ATOM    406  C4   DA A  19      56.486  46.193  54.139  1.00111.04           C  
ANISOU  406  C4   DA A  19     8422  20643  13127   4380  -1762  -1779       C  
TER     407       DA A  19                                                      
ATOM    408  N   ARG C 471      21.650  38.048  13.605  1.00 98.29           N  
ANISOU  408  N   ARG C 471    16893  11423   9031  -2677  -1232  -2044       N  
ATOM    409  CA  ARG C 471      22.397  37.608  14.824  1.00 97.59           C  
ANISOU  409  CA  ARG C 471    16428  11076   9575  -2564   -788  -1947       C  
ATOM    410  C   ARG C 471      23.585  38.512  15.250  1.00 96.05           C  
ANISOU  410  C   ARG C 471    16023  10869   9605  -2329   -477  -1581       C  
ATOM    411  O   ARG C 471      24.433  38.104  16.060  1.00 94.38           O  
ANISOU  411  O   ARG C 471    15484  10612   9764  -2157    -93  -1533       O  
ATOM    412  CB  ARG C 471      22.882  36.188  14.631  1.00100.09           C  
ANISOU  412  CB  ARG C 471    17145  11038   9848  -2629   -274  -2233       C  
ATOM    413  CG  ARG C 471      21.761  35.210  14.241  1.00115.91           C  
ANISOU  413  CG  ARG C 471    19498  12969  11573  -3138   -490  -2685       C  
ATOM    414  CD  ARG C 471      22.290  33.860  13.687  1.00131.47           C  
ANISOU  414  CD  ARG C 471    22305  14370  13276  -3204     73  -3028       C  
ATOM    415  NE  ARG C 471      23.231  33.232  14.618  1.00138.74           N  
ANISOU  415  NE  ARG C 471    23290  14824  14602  -2698    601  -2869       N  
ATOM    416  CZ  ARG C 471      24.549  33.468  14.684  1.00140.09           C  
ANISOU  416  CZ  ARG C 471    23275  15072  14882  -2022   1019  -2641       C  
ATOM    417  NH1 ARG C 471      25.161  34.315  13.859  1.00138.87           N  
ANISOU  417  NH1 ARG C 471    22945  15349  14472  -1933   1104  -2537       N  
ATOM    418  NH2 ARG C 471      25.279  32.840  15.598  1.00143.94           N  
ANISOU  418  NH2 ARG C 471    23748  15280  15663  -1439   1371  -2523       N  
ATOM    419  N   GLU C 472      23.613  39.754  14.760  1.00 96.11           N  
ANISOU  419  N   GLU C 472    16255  10938   9326  -2347   -668  -1336       N  
ATOM    420  CA  GLU C 472      24.697  40.693  15.075  1.00 94.02           C  
ANISOU  420  CA  GLU C 472    15909  10657   9157  -2425   -336  -1055       C  
ATOM    421  C   GLU C 472      24.169  42.027  15.657  1.00 92.06           C  
ANISOU  421  C   GLU C 472    15723  10264   8991  -2362   -775   -807       C  
ATOM    422  O   GLU C 472      23.328  42.724  15.051  1.00 94.78           O  
ANISOU  422  O   GLU C 472    16600  10486   8927  -2187  -1233   -699       O  
ATOM    423  CB  GLU C 472      25.502  40.970  13.801  1.00100.75           C  
ANISOU  423  CB  GLU C 472    17335  11534   9413  -2681     96   -990       C  
ATOM    424  CG  GLU C 472      26.999  41.231  14.011  1.00103.08           C  
ANISOU  424  CG  GLU C 472    17284  12099   9783  -2953    779   -929       C  
ATOM    425  CD  GLU C 472      27.728  41.860  12.790  1.00108.15           C  
ANISOU  425  CD  GLU C 472    18542  12820   9730  -3431   1259   -813       C  
ATOM    426  OE1 GLU C 472      27.234  41.799  11.632  1.00101.91           O  
ANISOU  426  OE1 GLU C 472    18524  11859   8337  -3430   1153   -803       O  
ATOM    427  OE2 GLU C 472      28.830  42.418  13.008  1.00111.36           O  
ANISOU  427  OE2 GLU C 472    18636  13548  10128  -3895   1774   -755       O  
ATOM    428  N   CYS C 473      24.668  42.395  16.827  1.00 85.30           N  
ANISOU  428  N   CYS C 473    14399   9427   8583  -2410   -658   -735       N  
ATOM    429  CA  CYS C 473      24.254  43.645  17.420  1.00 86.03           C  
ANISOU  429  CA  CYS C 473    14699   9271   8717  -2339   -991   -565       C  
ATOM    430  C   CYS C 473      24.743  44.704  16.490  1.00 91.55           C  
ANISOU  430  C   CYS C 473    16304   9621   8862  -2658   -815   -323       C  
ATOM    431  O   CYS C 473      25.961  44.880  16.305  1.00 90.92           O  
ANISOU  431  O   CYS C 473    16237   9630   8677  -3235   -243   -283       O  
ATOM    432  CB  CYS C 473      24.849  43.856  18.816  1.00 85.43           C  
ANISOU  432  CB  CYS C 473    14032   9304   9123  -2466   -843   -588       C  
ATOM    433  SG  CYS C 473      24.528  45.447  19.505  1.00 83.59           S  
ANISOU  433  SG  CYS C 473    14295   8619   8847  -2466  -1123   -458       S  
ATOM    434  N   SER C 474      23.781  45.384  15.876  1.00 94.51           N  
ANISOU  434  N   SER C 474    17438   9675   8796  -2271  -1296   -170       N  
ATOM    435  CA  SER C 474      24.090  46.458  14.962  1.00 98.64           C  
ANISOU  435  CA  SER C 474    19169   9670   8641  -2490  -1175    148       C  
ATOM    436  C   SER C 474      24.811  47.638  15.637  1.00 99.63           C  
ANISOU  436  C   SER C 474    19784   9270   8800  -2997   -875    307       C  
ATOM    437  O   SER C 474      25.114  48.615  14.946  1.00106.69           O  
ANISOU  437  O   SER C 474    21922   9547   9069  -3343   -682    599       O  
ATOM    438  CB  SER C 474      22.803  46.944  14.278  1.00103.41           C  
ANISOU  438  CB  SER C 474    20522  10073   8698  -1682  -1889    297       C  
ATOM    439  OG  SER C 474      21.842  47.408  15.214  1.00100.57           O  
ANISOU  439  OG  SER C 474    19909   9676   8627   -972  -2434    231       O  
ATOM    440  N   TYR C 475      25.063  47.584  16.954  1.00 90.65           N  
ANISOU  440  N   TYR C 475    17840   8320   8284  -3112   -829    114       N  
ATOM    441  CA  TYR C 475      25.718  48.723  17.641  1.00 98.57           C  
ANISOU  441  CA  TYR C 475    19343   8846   9261  -3725   -575    165       C  
ATOM    442  C   TYR C 475      27.140  48.454  18.063  1.00 99.14           C  
ANISOU  442  C   TYR C 475    18615   9501   9552  -4699     54    -24       C  
ATOM    443  O   TYR C 475      28.026  49.283  17.844  1.00106.70           O  
ANISOU  443  O   TYR C 475    20169  10229  10142  -5678    532     27       O  
ATOM    444  CB  TYR C 475      25.015  49.131  18.920  1.00 93.78           C  
ANISOU  444  CB  TYR C 475    18532   8054   9048  -3204  -1000     31       C  
ATOM    445  CG  TYR C 475      23.603  49.557  18.792  1.00 97.21           C  
ANISOU  445  CG  TYR C 475    19545   8104   9286  -2110  -1642    122       C  
ATOM    446  CD1 TYR C 475      23.268  50.885  18.642  1.00105.63           C  
ANISOU  446  CD1 TYR C 475    22069   8210   9854  -1811  -1802    329       C  
ATOM    447  CD2 TYR C 475      22.587  48.629  18.886  1.00101.77           C  
ANISOU  447  CD2 TYR C 475    19204   9331  10135  -1352  -2081    -42       C  
ATOM    448  CE1 TYR C 475      21.955  51.272  18.566  1.00115.20           C  
ANISOU  448  CE1 TYR C 475    23687   9241  10841   -535  -2442    375       C  
ATOM    449  CE2 TYR C 475      21.279  49.002  18.811  1.00103.76           C  
ANISOU  449  CE2 TYR C 475    19693   9556  10176   -318  -2688    -49       C  
ATOM    450  CZ  TYR C 475      20.967  50.315  18.660  1.00112.20           C  
ANISOU  450  CZ  TYR C 475    22073   9800  10758    208  -2897    157       C  
ATOM    451  OH  TYR C 475      19.649  50.644  18.583  1.00127.70           O  
ANISOU  451  OH  TYR C 475    24126  11930  12463   1483  -3547    112       O  
ATOM    452  N   CYS C 476      27.328  47.334  18.746  1.00 95.26           N  
ANISOU  452  N   CYS C 476    16799   9789   9605  -4428     39   -262       N  
ATOM    453  CA  CYS C 476      28.619  46.982  19.309  1.00 97.58           C  
ANISOU  453  CA  CYS C 476    16095  10875  10107  -5034    497   -483       C  
ATOM    454  C   CYS C 476      29.346  45.992  18.435  1.00101.98           C  
ANISOU  454  C   CYS C 476    16116  12096  10537  -5062    947   -556       C  
ATOM    455  O   CYS C 476      30.527  45.723  18.644  1.00104.23           O  
ANISOU  455  O   CYS C 476    15539  13219  10845  -5486   1396   -757       O  
ATOM    456  CB  CYS C 476      28.448  46.391  20.709  1.00 93.24           C  
ANISOU  456  CB  CYS C 476    14556  10748  10122  -4549    192   -665       C  
ATOM    457  SG  CYS C 476      27.680  44.801  20.782  1.00 82.53           S  
ANISOU  457  SG  CYS C 476    12587   9645   9125  -3551    -69   -693       S  
ATOM    458  N   GLY C 477      28.632  45.431  17.464  1.00103.94           N  
ANISOU  458  N   GLY C 477    16822  12072  10599  -4550    811   -451       N  
ATOM    459  CA  GLY C 477      29.226  44.496  16.533  1.00105.82           C  
ANISOU  459  CA  GLY C 477    16779  12804  10625  -4502   1258   -562       C  
ATOM    460  C   GLY C 477      29.433  43.090  17.050  1.00101.25           C  
ANISOU  460  C   GLY C 477    15233  12770  10469  -3833   1287   -795       C  
ATOM    461  O   GLY C 477      29.869  42.234  16.317  1.00104.76           O  
ANISOU  461  O   GLY C 477    15546  13531  10727  -3614   1655   -935       O  
ATOM    462  N   LYS C 478      29.127  42.811  18.299  1.00 97.82           N  
ANISOU  462  N   LYS C 478    14257  12382  10527  -3450    938   -835       N  
ATOM    463  CA  LYS C 478      29.310  41.446  18.772  1.00 96.70           C  
ANISOU  463  CA  LYS C 478    13498  12576  10670  -2757    990   -984       C  
ATOM    464  C   LYS C 478      28.283  40.557  18.078  1.00 92.29           C  
ANISOU  464  C   LYS C 478    13533  11497  10038  -2360    810  -1016       C  
ATOM    465  O   LYS C 478      27.283  41.039  17.531  1.00 90.78           O  
ANISOU  465  O   LYS C 478    13965  10857   9670  -2518    472   -931       O  
ATOM    466  CB  LYS C 478      29.230  41.357  20.314  1.00 95.27           C  
ANISOU  466  CB  LYS C 478    12729  12554  10916  -2482    678   -977       C  
ATOM    467  CG  LYS C 478      30.340  42.160  21.046  1.00102.39           C  
ANISOU  467  CG  LYS C 478    12932  14157  11815  -2958    826  -1053       C  
ATOM    468  CD  LYS C 478      30.491  41.833  22.545  1.00109.30           C  
ANISOU  468  CD  LYS C 478    13127  15418  12986  -2548    549  -1086       C  
ATOM    469  CE  LYS C 478      31.837  42.374  23.119  1.00120.07           C  
ANISOU  469  CE  LYS C 478    13552  17849  14219  -2999    728  -1285       C  
ATOM    470  NZ  LYS C 478      32.465  41.524  24.205  1.00120.74           N  
ANISOU  470  NZ  LYS C 478    12731  18758  14387  -2216    586  -1355       N  
ATOM    471  N   PHE C 479      28.578  39.263  18.088  1.00 91.27           N  
ANISOU  471  N   PHE C 479    13242  11471   9967  -1824   1040  -1172       N  
ATOM    472  CA  PHE C 479      27.771  38.237  17.453  1.00 89.17           C  
ANISOU  472  CA  PHE C 479    13591  10718   9570  -1591    982  -1311       C  
ATOM    473  C   PHE C 479      27.119  37.420  18.527  1.00 82.37           C  
ANISOU  473  C   PHE C 479    12686   9554   9056  -1273    737  -1314       C  
ATOM    474  O   PHE C 479      27.768  37.110  19.501  1.00 83.30           O  
ANISOU  474  O   PHE C 479    12357   9901   9393   -870    840  -1248       O  
ATOM    475  CB  PHE C 479      28.678  37.301  16.647  1.00 95.71           C  
ANISOU  475  CB  PHE C 479    14546  11719  10100  -1207   1558  -1530       C  
ATOM    476  CG  PHE C 479      28.844  37.707  15.229  1.00102.50           C  
ANISOU  476  CG  PHE C 479    15851  12658  10437  -1591   1816  -1605       C  
ATOM    477  CD1 PHE C 479      28.039  37.146  14.235  1.00114.43           C  
ANISOU  477  CD1 PHE C 479    18174  13714  11590  -1667   1722  -1781       C  
ATOM    478  CD2 PHE C 479      29.793  38.656  14.875  1.00107.52           C  
ANISOU  478  CD2 PHE C 479    16149  13859  10845  -1999   2173  -1524       C  
ATOM    479  CE1 PHE C 479      28.183  37.529  12.898  1.00117.11           C  
ANISOU  479  CE1 PHE C 479    19021  14152  11323  -1997   1941  -1830       C  
ATOM    480  CE2 PHE C 479      29.945  39.052  13.557  1.00109.89           C  
ANISOU  480  CE2 PHE C 479    17005  14198  10551  -2423   2476  -1545       C  
ATOM    481  CZ  PHE C 479      29.136  38.487  12.563  1.00119.11           C  
ANISOU  481  CZ  PHE C 479    19024  14897  11337  -2347   2338  -1675       C  
ATOM    482  N   PHE C 480      25.871  37.004  18.327  1.00 80.32           N  
ANISOU  482  N   PHE C 480    12894   8865   8759  -1480    442  -1414       N  
ATOM    483  CA  PHE C 480      25.091  36.339  19.391  1.00 76.76           C  
ANISOU  483  CA  PHE C 480    12445   8147   8574  -1446    255  -1417       C  
ATOM    484  C   PHE C 480      24.367  35.100  18.951  1.00 79.25           C  
ANISOU  484  C   PHE C 480    13457   7964   8690  -1632    350  -1678       C  
ATOM    485  O   PHE C 480      23.670  35.121  17.954  1.00 90.76           O  
ANISOU  485  O   PHE C 480    15226   9404   9856  -2040    189  -1896       O  
ATOM    486  CB  PHE C 480      24.090  37.348  19.922  1.00 76.63           C  
ANISOU  486  CB  PHE C 480    12080   8312   8724  -1761   -241  -1333       C  
ATOM    487  CG  PHE C 480      24.758  38.594  20.513  1.00 76.44           C  
ANISOU  487  CG  PHE C 480    11576   8602   8867  -1686   -318  -1119       C  
ATOM    488  CD1 PHE C 480      25.251  38.581  21.790  1.00 63.19           C  
ANISOU  488  CD1 PHE C 480     9462   7093   7453  -1473   -279  -1006       C  
ATOM    489  CD2 PHE C 480      24.955  39.718  19.754  1.00 84.04           C  
ANISOU  489  CD2 PHE C 480    12669   9642   9619  -1890   -390  -1047       C  
ATOM    490  CE1 PHE C 480      25.868  39.657  22.308  1.00 76.50           C  
ANISOU  490  CE1 PHE C 480    10764   9083   9220  -1562   -338   -909       C  
ATOM    491  CE2 PHE C 480      25.589  40.798  20.277  1.00 88.84           C  
ANISOU  491  CE2 PHE C 480    13033  10412  10309  -2018   -381   -911       C  
ATOM    492  CZ  PHE C 480      26.039  40.767  21.554  1.00 84.33           C  
ANISOU  492  CZ  PHE C 480    11941  10073  10029  -1900   -364   -882       C  
ATOM    493  N   ARG C 481      24.504  34.017  19.693  1.00 79.37           N  
ANISOU  493  N   ARG C 481    13828   7549   8779  -1378    599  -1669       N  
ATOM    494  CA  ARG C 481      24.012  32.692  19.243  1.00 82.57           C  
ANISOU  494  CA  ARG C 481    15217   7255   8900  -1628    845  -1957       C  
ATOM    495  C   ARG C 481      22.588  32.598  18.669  1.00 81.29           C  
ANISOU  495  C   ARG C 481    15254   7098   8535  -2593    551  -2292       C  
ATOM    496  O   ARG C 481      22.251  31.597  18.065  1.00 88.58           O  
ANISOU  496  O   ARG C 481    17031   7502   9126  -2986    765  -2631       O  
ATOM    497  CB  ARG C 481      24.105  31.677  20.387  1.00 84.95           C  
ANISOU  497  CB  ARG C 481    16052   6955   9270  -1340   1097  -1808       C  
ATOM    498  CG  ARG C 481      23.025  31.850  21.475  1.00 90.80           C  
ANISOU  498  CG  ARG C 481    16509   7789  10201  -1971    839  -1710       C  
ATOM    499  CD  ARG C 481      23.424  31.195  22.818  1.00 96.02           C  
ANISOU  499  CD  ARG C 481    17556   8025  10904  -1477   1061  -1380       C  
ATOM    500  NE  ARG C 481      22.368  31.231  23.839  1.00 81.13           N  
ANISOU  500  NE  ARG C 481    15535   6203   9088  -2184    948  -1318       N  
ATOM    501  CZ  ARG C 481      22.372  30.487  24.948  1.00 91.70           C  
ANISOU  501  CZ  ARG C 481    17525   7020  10298  -2072   1192  -1059       C  
ATOM    502  NH1 ARG C 481      23.369  29.633  25.215  1.00 94.76           N  
ANISOU  502  NH1 ARG C 481    18805   6729  10472  -1115   1490   -808       N  
ATOM    503  NH2 ARG C 481      21.360  30.582  25.801  1.00100.67           N  
ANISOU  503  NH2 ARG C 481    18465   8346  11439  -2852   1157  -1050       N  
ATOM    504  N   SER C 482      21.742  33.594  18.893  1.00 78.98           N  
ANISOU  504  N   SER C 482    14193   7433   8384  -2948     62  -2252       N  
ATOM    505  CA  SER C 482      20.385  33.563  18.372  1.00 81.08           C  
ANISOU  505  CA  SER C 482    14371   8037   8397  -3737   -298  -2619       C  
ATOM    506  C   SER C 482      19.800  34.946  18.225  1.00 82.59           C  
ANISOU  506  C   SER C 482    13729   9028   8624  -3624   -878  -2535       C  
ATOM    507  O   SER C 482      20.289  35.934  18.821  1.00 76.86           O  
ANISOU  507  O   SER C 482    12556   8456   8193  -3106   -971  -2186       O  
ATOM    508  CB  SER C 482      19.497  32.826  19.349  1.00 85.60           C  
ANISOU  508  CB  SER C 482    14980   8496   9047  -4387   -207  -2756       C  
ATOM    509  OG  SER C 482      19.412  33.545  20.600  1.00 83.54           O  
ANISOU  509  OG  SER C 482    13982   8589   9171  -4100   -342  -2441       O  
ATOM    510  N   ASN C 483      18.707  34.994  17.478  1.00 89.46           N  
ANISOU  510  N   ASN C 483    14440  10419   9131  -4101  -1288  -2893       N  
ATOM    511  CA  ASN C 483      17.889  36.193  17.384  1.00 93.90           C  
ANISOU  511  CA  ASN C 483    14260  11801   9617  -3853  -1917  -2870       C  
ATOM    512  C   ASN C 483      17.244  36.460  18.733  1.00 90.57           C  
ANISOU  512  C   ASN C 483    13094  11753   9565  -3870  -1999  -2832       C  
ATOM    513  O   ASN C 483      17.308  37.559  19.249  1.00 86.78           O  
ANISOU  513  O   ASN C 483    12208  11473   9290  -3266  -2220  -2568       O  
ATOM    514  CB  ASN C 483      16.814  36.026  16.296  1.00104.64           C  
ANISOU  514  CB  ASN C 483    15510  13854  10394  -4296  -2396  -3337       C  
ATOM    515  CG  ASN C 483      16.506  37.331  15.586  1.00115.64           C  
ANISOU  515  CG  ASN C 483    16655  15824  11458  -3595  -3030  -3177       C  
ATOM    516  OD1 ASN C 483      15.686  38.127  16.058  1.00118.31           O  
ANISOU  516  OD1 ASN C 483    16257  16858  11838  -3199  -3496  -3175       O  
ATOM    517  ND2 ASN C 483      17.169  37.561  14.440  1.00126.58           N  
ANISOU  517  ND2 ASN C 483    18761  16897  12437  -3363  -3016  -3036       N  
ATOM    518  N   TYR C 484      16.630  35.433  19.310  1.00 93.11           N  
ANISOU  518  N   TYR C 484    13363  12109   9905  -4638  -1753  -3120       N  
ATOM    519  CA  TYR C 484      16.022  35.551  20.626  1.00 90.75           C  
ANISOU  519  CA  TYR C 484    12414  12193   9874  -4783  -1701  -3109       C  
ATOM    520  C   TYR C 484      16.888  36.403  21.507  1.00 83.30           C  
ANISOU  520  C   TYR C 484    11386  10930   9334  -3956  -1627  -2621       C  
ATOM    521  O   TYR C 484      16.427  37.422  22.034  1.00 83.12           O  
ANISOU  521  O   TYR C 484    10700  11461   9422  -3520  -1939  -2579       O  
ATOM    522  CB  TYR C 484      15.837  34.169  21.265  1.00 96.66           C  
ANISOU  522  CB  TYR C 484    13658  12474  10593  -5721  -1145  -3270       C  
ATOM    523  CG  TYR C 484      15.133  34.147  22.611  1.00100.32           C  
ANISOU  523  CG  TYR C 484    13542  13375  11200  -6089   -979  -3289       C  
ATOM    524  CD1 TYR C 484      13.758  34.368  22.714  1.00112.27           C  
ANISOU  524  CD1 TYR C 484    14018  16125  12515  -6662  -1241  -3753       C  
ATOM    525  CD2 TYR C 484      15.843  33.863  23.779  1.00 92.05           C  
ANISOU  525  CD2 TYR C 484    12951  11628  10398  -5852   -546  -2874       C  
ATOM    526  CE1 TYR C 484      13.120  34.349  23.958  1.00119.78           C  
ANISOU  526  CE1 TYR C 484    14394  17581  13537  -7034   -990  -3805       C  
ATOM    527  CE2 TYR C 484      15.212  33.823  25.023  1.00 95.45           C  
ANISOU  527  CE2 TYR C 484    12958  12449  10860  -6228   -338  -2878       C  
ATOM    528  CZ  TYR C 484      13.863  34.079  25.112  1.00111.83           C  
ANISOU  528  CZ  TYR C 484    14006  15724  12762  -6845   -514  -3344       C  
ATOM    529  OH  TYR C 484      13.267  34.041  26.350  1.00113.80           O  
ANISOU  529  OH  TYR C 484    13812  16438  12989  -7240   -213  -3373       O  
ATOM    530  N   TYR C 485      18.143  35.991  21.680  1.00 78.10           N  
ANISOU  530  N   TYR C 485    11386   9448   8842  -3704  -1222  -2308       N  
ATOM    531  CA  TYR C 485      19.003  36.685  22.629  1.00 71.51           C  
ANISOU  531  CA  TYR C 485    10390   8449   8333  -3091  -1144  -1921       C  
ATOM    532  C   TYR C 485      19.358  38.055  22.090  1.00 72.90           C  
ANISOU  532  C   TYR C 485    10380   8807   8510  -2555  -1482  -1777       C  
ATOM    533  O   TYR C 485      19.332  39.041  22.819  1.00 76.02           O  
ANISOU  533  O   TYR C 485    10426   9390   9067  -2216  -1654  -1652       O  
ATOM    534  CB  TYR C 485      20.272  35.906  23.008  1.00 66.89           C  
ANISOU  534  CB  TYR C 485    10376   7192   7847  -2839   -684  -1660       C  
ATOM    535  CG  TYR C 485      21.084  36.675  24.047  1.00 75.16           C  
ANISOU  535  CG  TYR C 485    11065   8342   9150  -2309   -700  -1347       C  
ATOM    536  CD1 TYR C 485      20.750  36.649  25.393  1.00 72.39           C  
ANISOU  536  CD1 TYR C 485    10474   8124   8906  -2341   -668  -1258       C  
ATOM    537  CD2 TYR C 485      22.140  37.482  23.677  1.00 79.33           C  
ANISOU  537  CD2 TYR C 485    11485   8923   9734  -1911   -738  -1193       C  
ATOM    538  CE1 TYR C 485      21.459  37.378  26.325  1.00 65.44           C  
ANISOU  538  CE1 TYR C 485     9279   7410   8173  -1927   -734  -1047       C  
ATOM    539  CE2 TYR C 485      22.856  38.226  24.626  1.00 77.16           C  
ANISOU  539  CE2 TYR C 485    10844   8848   9624  -1625   -778  -1008       C  
ATOM    540  CZ  TYR C 485      22.508  38.184  25.955  1.00 75.79           C  
ANISOU  540  CZ  TYR C 485    10449   8800   9549  -1602   -814   -948       C  
ATOM    541  OH  TYR C 485      23.236  38.946  26.916  1.00 77.35           O  
ANISOU  541  OH  TYR C 485    10304   9255   9830  -1372   -895   -828       O  
ATOM    542  N   LEU C 486      19.670  38.149  20.808  1.00 76.90           N  
ANISOU  542  N   LEU C 486    11264   9196   8760  -2516  -1547  -1804       N  
ATOM    543  CA  LEU C 486      19.967  39.453  20.265  1.00 75.88           C  
ANISOU  543  CA  LEU C 486    11204   9114   8513  -2112  -1810  -1622       C  
ATOM    544  C   LEU C 486      18.860  40.418  20.679  1.00 78.76           C  
ANISOU  544  C   LEU C 486    11124   9950   8852  -1807  -2297  -1698       C  
ATOM    545  O   LEU C 486      19.138  41.527  21.148  1.00 80.17           O  
ANISOU  545  O   LEU C 486    11344   9994   9124  -1414  -2396  -1505       O  
ATOM    546  CB  LEU C 486      20.145  39.390  18.756  1.00 76.13           C  
ANISOU  546  CB  LEU C 486    11755   9062   8110  -2177  -1854  -1672       C  
ATOM    547  CG  LEU C 486      20.447  40.688  17.963  1.00 84.36           C  
ANISOU  547  CG  LEU C 486    13197  10018   8836  -1853  -2067  -1432       C  
ATOM    548  CD1 LEU C 486      21.423  41.637  18.677  1.00 78.52           C  
ANISOU  548  CD1 LEU C 486    12509   8979   8347  -1725  -1845  -1132       C  
ATOM    549  CD2 LEU C 486      20.921  40.401  16.491  1.00 77.96           C  
ANISOU  549  CD2 LEU C 486    13026   9069   7525  -2014  -1912  -1447       C  
ATOM    550  N   ASN C 487      17.619  39.970  20.559  1.00 83.38           N  
ANISOU  550  N   ASN C 487    11276  11133   9273  -2006  -2564  -2035       N  
ATOM    551  CA  ASN C 487      16.477  40.802  20.885  1.00 91.33           C  
ANISOU  551  CA  ASN C 487    11687  12836  10177  -1554  -3038  -2198       C  
ATOM    552  C   ASN C 487      16.693  41.398  22.247  1.00 84.82           C  
ANISOU  552  C   ASN C 487    10643  11875   9710  -1261  -2882  -2055       C  
ATOM    553  O   ASN C 487      16.627  42.615  22.446  1.00 90.48           O  
ANISOU  553  O   ASN C 487    11471  12527  10380   -585  -3133  -1946       O  
ATOM    554  CB  ASN C 487      15.167  39.986  20.852  1.00101.20           C  
ANISOU  554  CB  ASN C 487    12196  15017  11238  -2058  -3203  -2689       C  
ATOM    555  CG  ASN C 487      13.930  40.837  21.175  1.00112.76           C  
ANISOU  555  CG  ASN C 487    12795  17517  12533  -1429  -3703  -2944       C  
ATOM    556  OD1 ASN C 487      13.662  41.177  22.335  1.00108.65           O  
ANISOU  556  OD1 ASN C 487    11812  17213  12256  -1211  -3572  -2972       O  
ATOM    557  ND2 ASN C 487      13.178  41.185  20.137  1.00125.05           N  
ANISOU  557  ND2 ASN C 487    14129  19789  13594  -1027  -4292  -3152       N  
ATOM    558  N   ILE C 488      16.980  40.503  23.169  1.00 79.16           N  
ANISOU  558  N   ILE C 488     9782  11024   9270  -1766  -2451  -2057       N  
ATOM    559  CA  ILE C 488      17.307  40.839  24.557  1.00 77.07           C  
ANISOU  559  CA  ILE C 488     9357  10641   9284  -1613  -2245  -1926       C  
ATOM    560  C   ILE C 488      18.541  41.738  24.703  1.00 72.15           C  
ANISOU  560  C   ILE C 488     9212   9417   8783  -1275  -2189  -1612       C  
ATOM    561  O   ILE C 488      18.482  42.776  25.370  1.00 77.51           O  
ANISOU  561  O   ILE C 488     9864  10087   9497   -884  -2319  -1604       O  
ATOM    562  CB  ILE C 488      17.526  39.508  25.340  1.00 76.13           C  
ANISOU  562  CB  ILE C 488     9266  10367   9295  -2227  -1774  -1903       C  
ATOM    563  CG1 ILE C 488      16.177  38.950  25.861  1.00 84.93           C  
ANISOU  563  CG1 ILE C 488     9785  12199  10287  -2719  -1718  -2252       C  
ATOM    564  CG2 ILE C 488      18.490  39.677  26.413  1.00 68.32           C  
ANISOU  564  CG2 ILE C 488     8432   9024   8504  -2030  -1549  -1629       C  
ATOM    565  CD1 ILE C 488      16.146  37.391  26.089  1.00 72.17           C  
ANISOU  565  CD1 ILE C 488     8559  10275   8588  -3612  -1233  -2287       C  
ATOM    566  N   HIS C 489      19.651  41.328  24.088  1.00 65.80           N  
ANISOU  566  N   HIS C 489     8839   8172   7992  -1480  -1956  -1420       N  
ATOM    567  CA  HIS C 489      20.902  42.068  24.185  1.00 64.80           C  
ANISOU  567  CA  HIS C 489     9013   7685   7923  -1404  -1824  -1197       C  
ATOM    568  C   HIS C 489      20.781  43.503  23.730  1.00 65.82           C  
ANISOU  568  C   HIS C 489     9551   7602   7855  -1128  -2094  -1148       C  
ATOM    569  O   HIS C 489      21.501  44.373  24.190  1.00 70.17           O  
ANISOU  569  O   HIS C 489    10345   7886   8429  -1177  -2015  -1060       O  
ATOM    570  CB  HIS C 489      22.003  41.395  23.368  1.00 65.46           C  
ANISOU  570  CB  HIS C 489     9362   7559   7952  -1618  -1507  -1081       C  
ATOM    571  CG  HIS C 489      23.149  42.302  23.006  1.00 56.27           C  
ANISOU  571  CG  HIS C 489     8456   6228   6695  -1715  -1371   -935       C  
ATOM    572  ND1 HIS C 489      24.230  42.504  23.833  1.00 61.04           N  
ANISOU  572  ND1 HIS C 489     8795   6966   7433  -1834  -1165   -880       N  
ATOM    573  CD2 HIS C 489      23.398  43.019  21.877  1.00 64.81           C  
ANISOU  573  CD2 HIS C 489    10057   7090   7479  -1828  -1373   -852       C  
ATOM    574  CE1 HIS C 489      25.082  43.329  23.237  1.00 74.99           C  
ANISOU  574  CE1 HIS C 489    10826   8653   9013  -2149  -1012   -822       C  
ATOM    575  NE2 HIS C 489      24.615  43.631  22.035  1.00 62.60           N  
ANISOU  575  NE2 HIS C 489     9820   6793   7173  -2159  -1091   -770       N  
ATOM    576  N   LEU C 490      19.862  43.753  22.834  1.00 67.99           N  
ANISOU  576  N   LEU C 490     9988   7986   7858   -843  -2425  -1221       N  
ATOM    577  CA  LEU C 490      19.710  45.086  22.329  1.00 75.68           C  
ANISOU  577  CA  LEU C 490    11619   8614   8521   -409  -2699  -1109       C  
ATOM    578  C   LEU C 490      19.134  46.031  23.372  1.00 79.04           C  
ANISOU  578  C   LEU C 490    12007   9025   9001    110  -2891  -1221       C  
ATOM    579  O   LEU C 490      19.417  47.239  23.356  1.00 83.26           O  
ANISOU  579  O   LEU C 490    13351   8953   9332    356  -2947  -1103       O  
ATOM    580  CB  LEU C 490      18.844  45.058  21.085  1.00 82.41           C  
ANISOU  580  CB  LEU C 490    12655   9707   8951    -53  -3093  -1148       C  
ATOM    581  CG  LEU C 490      19.594  44.483  19.880  1.00 81.19           C  
ANISOU  581  CG  LEU C 490    12915   9353   8579   -526  -2868  -1014       C  
ATOM    582  CD1 LEU C 490      18.589  44.122  18.862  1.00 81.31           C  
ANISOU  582  CD1 LEU C 490    12860   9849   8183   -281  -3295  -1173       C  
ATOM    583  CD2 LEU C 490      20.641  45.474  19.322  1.00 79.07           C  
ANISOU  583  CD2 LEU C 490    13622   8382   8038   -681  -2641   -691       C  
ATOM    584  N   ARG C 491      18.373  45.483  24.304  1.00 76.02           N  
ANISOU  584  N   ARG C 491    10809   9241   8835    207  -2915  -1466       N  
ATOM    585  CA  ARG C 491      17.752  46.310  25.299  1.00 78.45           C  
ANISOU  585  CA  ARG C 491    11010   9655   9141    772  -3049  -1645       C  
ATOM    586  C   ARG C 491      18.786  47.184  25.963  1.00 79.30           C  
ANISOU  586  C   ARG C 491    11779   9045   9306    580  -2837  -1531       C  
ATOM    587  O   ARG C 491      18.527  48.345  26.319  1.00 88.48           O  
ANISOU  587  O   ARG C 491    13521   9814  10282   1119  -2975  -1615       O  
ATOM    588  CB  ARG C 491      17.047  45.445  26.316  1.00 78.12           C  
ANISOU  588  CB  ARG C 491     9990  10385   9306    610  -2915  -1904       C  
ATOM    589  CG  ARG C 491      15.904  44.661  25.725  1.00 82.69           C  
ANISOU  589  CG  ARG C 491     9854  11810   9752    606  -3107  -2140       C  
ATOM    590  CD  ARG C 491      15.274  43.763  26.744  1.00 85.66           C  
ANISOU  590  CD  ARG C 491     9385  12897  10264    159  -2832  -2390       C  
ATOM    591  NE  ARG C 491      14.371  42.808  26.105  1.00 98.99           N  
ANISOU  591  NE  ARG C 491    10448  15361  11801   -282  -2907  -2651       N  
ATOM    592  CZ  ARG C 491      13.939  41.668  26.653  1.00101.64           C  
ANISOU  592  CZ  ARG C 491    10277  16163  12178  -1114  -2553  -2834       C  
ATOM    593  NH1 ARG C 491      14.300  41.292  27.881  1.00 98.13           N  
ANISOU  593  NH1 ARG C 491     9887  15500  11900  -1469  -2113  -2723       N  
ATOM    594  NH2 ARG C 491      13.123  40.890  25.960  1.00106.21           N  
ANISOU  594  NH2 ARG C 491    10377  17434  12543  -1670  -2634  -3145       N  
ATOM    595  N   THR C 492      19.983  46.651  26.118  1.00 72.56           N  
ANISOU  595  N   THR C 492    10881   8043   8647   -175  -2503  -1383       N  
ATOM    596  CA  THR C 492      20.970  47.411  26.859  1.00 74.41           C  
ANISOU  596  CA  THR C 492    11514   7865   8891   -533  -2319  -1380       C  
ATOM    597  C   THR C 492      21.590  48.524  26.064  1.00 76.56           C  
ANISOU  597  C   THR C 492    12857   7370   8864   -738  -2288  -1241       C  
ATOM    598  O   THR C 492      22.387  49.242  26.619  1.00 81.15           O  
ANISOU  598  O   THR C 492    13852   7602   9379  -1221  -2118  -1307       O  
ATOM    599  CB  THR C 492      22.110  46.523  27.390  1.00 69.47           C  
ANISOU  599  CB  THR C 492    10341   7569   8487  -1178  -2017  -1315       C  
ATOM    600  OG1 THR C 492      22.910  46.061  26.316  1.00 72.38           O  
ANISOU  600  OG1 THR C 492    10788   7889   8823  -1548  -1838  -1132       O  
ATOM    601  CG2 THR C 492      21.522  45.303  28.060  1.00 85.69           C  
ANISOU  601  CG2 THR C 492    11639  10186  10734  -1034  -1983  -1361       C  
ATOM    602  N   HIS C 493      21.312  48.618  24.766  1.00 78.39           N  
ANISOU  602  N   HIS C 493    13579   7363   8841   -524  -2412  -1055       N  
ATOM    603  CA  HIS C 493      21.652  49.822  24.006  1.00 86.26           C  
ANISOU  603  CA  HIS C 493    15910   7470   9395   -597  -2391   -875       C  
ATOM    604  C   HIS C 493      20.437  50.708  23.932  1.00 90.26           C  
ANISOU  604  C   HIS C 493    17109   7602   9582    535  -2817   -913       C  
ATOM    605  O   HIS C 493      20.535  51.910  24.100  1.00 99.62           O  
ANISOU  605  O   HIS C 493    19501   7898  10450    696  -2803   -897       O  
ATOM    606  CB  HIS C 493      22.059  49.495  22.578  1.00 87.98           C  
ANISOU  606  CB  HIS C 493    16464   7611   9355   -914  -2280   -606       C  
ATOM    607  CG  HIS C 493      23.160  48.492  22.465  1.00 81.66           C  
ANISOU  607  CG  HIS C 493    14898   7320   8808  -1751  -1865   -601       C  
ATOM    608  ND1 HIS C 493      24.389  48.673  23.062  1.00 68.04           N  
ANISOU  608  ND1 HIS C 493    12998   5661   7193  -2589  -1476   -677       N  
ATOM    609  CD2 HIS C 493      23.240  47.331  21.766  1.00 74.54           C  
ANISOU  609  CD2 HIS C 493    13421   6914   7988  -1808  -1779   -568       C  
ATOM    610  CE1 HIS C 493      25.163  47.637  22.771  1.00 80.12           C  
ANISOU  610  CE1 HIS C 493    13759   7801   8880  -2949  -1189   -675       C  
ATOM    611  NE2 HIS C 493      24.488  46.806  21.995  1.00 71.46           N  
ANISOU  611  NE2 HIS C 493    12511   6864   7777  -2476  -1338   -605       N  
ATOM    612  N   THR C 494      19.299  50.086  23.657  1.00 89.42           N  
ANISOU  612  N   THR C 494    16251   8222   9502   1317  -3185  -1001       N  
ATOM    613  CA  THR C 494      18.054  50.784  23.414  1.00100.84           C  
ANISOU  613  CA  THR C 494    18069   9677  10570   2624  -3677  -1070       C  
ATOM    614  C   THR C 494      17.530  51.472  24.658  1.00104.93           C  
ANISOU  614  C   THR C 494    18587  10130  11151   3284  -3719  -1378       C  
ATOM    615  O   THR C 494      16.974  52.549  24.579  1.00115.68           O  
ANISOU  615  O   THR C 494    20933  10930  12090   4341  -3974  -1393       O  
ATOM    616  CB  THR C 494      16.955  49.820  22.869  1.00102.16           C  
ANISOU  616  CB  THR C 494    17073  11018  10726   3115  -4063  -1219       C  
ATOM    617  OG1 THR C 494      16.783  48.706  23.751  1.00102.56           O  
ANISOU  617  OG1 THR C 494    15749  11940  11279   2580  -3856  -1497       O  
ATOM    618  CG2 THR C 494      17.334  49.292  21.514  1.00 97.49           C  
ANISOU  618  CG2 THR C 494    16736  10404   9903   2662  -4091   -961       C  
ATOM    619  N   GLY C 495      17.714  50.851  25.809  1.00101.13           N  
ANISOU  619  N   GLY C 495    17117  10185  11121   2744  -3455  -1621       N  
ATOM    620  CA  GLY C 495      17.190  51.404  27.042  1.00105.43           C  
ANISOU  620  CA  GLY C 495    17568  10806  11684   3328  -3444  -1967       C  
ATOM    621  C   GLY C 495      15.977  50.650  27.552  1.00106.89           C  
ANISOU  621  C   GLY C 495    16302  12300  12012   3888  -3582  -2293       C  
ATOM    622  O   GLY C 495      15.636  50.766  28.731  1.00105.92           O  
ANISOU  622  O   GLY C 495    15763  12513  11968   4096  -3431  -2611       O  
ATOM    623  N   GLU C 496      15.319  49.869  26.694  1.00109.01           N  
ANISOU  623  N   GLU C 496    15786  13382  12251   4015  -3828  -2268       N  
ATOM    624  CA  GLU C 496      14.180  49.078  27.162  1.00113.76           C  
ANISOU  624  CA  GLU C 496    14917  15367  12940   4224  -3879  -2641       C  
ATOM    625  C   GLU C 496      14.572  48.267  28.418  1.00109.19           C  
ANISOU  625  C   GLU C 496    13678  15068  12743   3267  -3385  -2744       C  
ATOM    626  O   GLU C 496      15.611  47.578  28.449  1.00100.18           O  
ANISOU  626  O   GLU C 496    12684  13516  11863   2253  -3106  -2479       O  
ATOM    627  CB  GLU C 496      13.617  48.158  26.067  1.00115.68           C  
ANISOU  627  CB  GLU C 496    14412  16449  13094   4016  -4141  -2646       C  
ATOM    628  CG  GLU C 496      12.150  47.708  26.320  1.00125.04           C  
ANISOU  628  CG  GLU C 496    14124  19249  14138   4455  -4325  -3150       C  
ATOM    629  CD  GLU C 496      11.686  46.527  25.437  1.00128.28           C  
ANISOU  629  CD  GLU C 496    13670  20583  14486   3715  -4463  -3267       C  
ATOM    630  OE1 GLU C 496      12.512  45.941  24.678  1.00117.83           O  
ANISOU  630  OE1 GLU C 496    12911  18593  13266   2898  -4371  -2953       O  
ATOM    631  OE2 GLU C 496      10.479  46.185  25.514  1.00134.78           O  
ANISOU  631  OE2 GLU C 496    13218  22885  15109   3912  -4636  -3741       O  
ATOM    632  N   LYS C 497      13.756  48.428  29.464  1.00112.74           N  
ANISOU  632  N   LYS C 497    13480  16223  13133   3735  -3280  -3128       N  
ATOM    633  CA  LYS C 497      13.865  47.670  30.706  1.00107.22           C  
ANISOU  633  CA  LYS C 497    12147  15959  12631   2975  -2827  -3245       C  
ATOM    634  C   LYS C 497      12.444  47.285  31.067  1.00112.64           C  
ANISOU  634  C   LYS C 497    11564  18080  13154   3311  -2784  -3698       C  
ATOM    635  O   LYS C 497      11.714  48.076  31.656  1.00117.54           O  
ANISOU  635  O   LYS C 497    11970  19149  13542   4278  -2812  -4070       O  
ATOM    636  CB  LYS C 497      14.473  48.523  31.813  1.00106.95           C  
ANISOU  636  CB  LYS C 497    12825  15253  12556   3123  -2638  -3312       C  
ATOM    637  CG  LYS C 497      15.967  48.797  31.659  1.00101.68           C  
ANISOU  637  CG  LYS C 497    13177  13440  12018   2454  -2589  -2959       C  
ATOM    638  CD  LYS C 497      16.470  49.727  32.770  1.00 93.66           C  
ANISOU  638  CD  LYS C 497    12853  11877  10856   2518  -2449  -3156       C  
ATOM    639  CE  LYS C 497      17.834  50.315  32.467  1.00 86.49           C  
ANISOU  639  CE  LYS C 497    12990   9924   9948   1881  -2450  -2935       C  
ATOM    640  NZ  LYS C 497      18.352  51.105  33.616  1.00 91.04           N  
ANISOU  640  NZ  LYS C 497    14167  10093  10329   1686  -2312  -3215       N  
ATOM    641  N   PRO C 498      12.029  46.081  30.672  1.00112.67           N  
ANISOU  641  N   PRO C 498    10734  18854  13220   2494  -2689  -3726       N  
ATOM    642  CA  PRO C 498      10.646  45.658  30.821  1.00122.03           C  
ANISOU  642  CA  PRO C 498    10569  21614  14184   2553  -2641  -4223       C  
ATOM    643  C   PRO C 498      10.351  44.896  32.095  1.00122.41           C  
ANISOU  643  C   PRO C 498     9988  22302  14220   1694  -2019  -4407       C  
ATOM    644  O   PRO C 498       9.182  44.748  32.449  1.00134.77           O  
ANISOU  644  O   PRO C 498    10377  25298  15531   1760  -1864  -4905       O  
ATOM    645  CB  PRO C 498      10.445  44.736  29.623  1.00121.75           C  
ANISOU  645  CB  PRO C 498    10184  21934  14142   1845  -2843  -4176       C  
ATOM    646  CG  PRO C 498      11.753  44.101  29.445  1.00113.03           C  
ANISOU  646  CG  PRO C 498    10063  19543  13339    941  -2627  -3660       C  
ATOM    647  CD  PRO C 498      12.794  45.121  29.863  1.00108.16           C  
ANISOU  647  CD  PRO C 498    10497  17747  12853   1519  -2655  -3355       C  
ATOM    648  N   TYR C 499      11.381  44.397  32.764  1.00112.73           N  
ANISOU  648  N   TYR C 499     9496  20150  13186    900  -1659  -4021       N  
ATOM    649  CA  TYR C 499      11.176  43.689  34.014  1.00114.01           C  
ANISOU  649  CA  TYR C 499     9333  20767  13220    128  -1062  -4098       C  
ATOM    650  C   TYR C 499      11.117  44.692  35.166  1.00118.62           C  
ANISOU  650  C   TYR C 499    10023  21418  13628    923   -935  -4320       C  
ATOM    651  O   TYR C 499      12.134  45.316  35.537  1.00113.13           O  
ANISOU  651  O   TYR C 499    10279  19682  13023   1212  -1040  -4075       O  
ATOM    652  CB  TYR C 499      12.274  42.650  34.249  1.00107.86           C  
ANISOU  652  CB  TYR C 499     9357  19033  12592   -889   -780  -3570       C  
ATOM    653  CG  TYR C 499      12.195  41.475  33.320  1.00105.35           C  
ANISOU  653  CG  TYR C 499     9011  18677  12342  -1792   -728  -3447       C  
ATOM    654  CD1 TYR C 499      13.261  41.131  32.505  1.00 95.34           C  
ANISOU  654  CD1 TYR C 499     8548  16366  11309  -1927   -919  -3031       C  
ATOM    655  CD2 TYR C 499      11.028  40.713  33.244  1.00117.62           C  
ANISOU  655  CD2 TYR C 499     9712  21320  13660  -2579   -448  -3827       C  
ATOM    656  CE1 TYR C 499      13.166  40.037  31.624  1.00105.53           C  
ANISOU  656  CE1 TYR C 499     9945  17553  12600  -2722   -840  -2987       C  
ATOM    657  CE2 TYR C 499      10.920  39.634  32.375  1.00118.43           C  
ANISOU  657  CE2 TYR C 499     9917  21331  13752  -3545   -385  -3804       C  
ATOM    658  CZ  TYR C 499      11.988  39.292  31.573  1.00110.22           C  
ANISOU  658  CZ  TYR C 499     9834  19099  12946  -3564   -583  -3380       C  
ATOM    659  OH  TYR C 499      11.858  38.215  30.723  1.00116.23           O  
ANISOU  659  OH  TYR C 499    10821  19708  13634  -4494   -482  -3423       O  
ATOM    660  N   LYS C 500       9.918  44.812  35.734  1.00127.30           N  
ANISOU  660  N   LYS C 500    10096  23853  14421   1187   -674  -4850       N  
ATOM    661  CA  LYS C 500       9.594  45.821  36.727  1.00131.12           C  
ANISOU  661  CA  LYS C 500    10542  24635  14643   2150   -535  -5225       C  
ATOM    662  C   LYS C 500       9.609  45.202  38.119  1.00130.37           C  
ANISOU  662  C   LYS C 500    10377  24872  14284   1290    144  -5235       C  
ATOM    663  O   LYS C 500       9.148  44.075  38.304  1.00131.45           O  
ANISOU  663  O   LYS C 500     9932  25725  14288    146    595  -5222       O  
ATOM    664  CB  LYS C 500       8.208  46.384  36.433  1.00144.12           C  
ANISOU  664  CB  LYS C 500    10977  27761  16022   3218   -667  -5872       C  
ATOM    665  CG  LYS C 500       7.943  46.699  34.959  1.00148.58           C  
ANISOU  665  CG  LYS C 500    11382  28380  16693   3947  -1350  -5861       C  
ATOM    666  CD  LYS C 500       6.458  47.015  34.753  1.00171.65           C  
ANISOU  666  CD  LYS C 500    12754  33227  19239   4941  -1476  -6558       C  
ATOM    667  CE  LYS C 500       6.127  47.299  33.286  1.00175.78           C  
ANISOU  667  CE  LYS C 500    13073  33990  19726   5767  -2242  -6551       C  
ATOM    668  NZ  LYS C 500       4.666  47.317  33.050  1.00186.67           N  
ANISOU  668  NZ  LYS C 500    12604  37637  20685   6480  -2394  -7263       N  
ATOM    669  N   CYS C 501      10.142  45.943  39.093  1.00128.84           N  
ANISOU  669  N   CYS C 501    10906  24114  13933   1770    230  -5265       N  
ATOM    670  CA  CYS C 501      10.191  45.482  40.479  1.00128.63           C  
ANISOU  670  CA  CYS C 501    10953  24395  13524   1105    832  -5269       C  
ATOM    671  C   CYS C 501       8.876  45.798  41.123  1.00138.85           C  
ANISOU  671  C   CYS C 501    11168  27204  14385   1577   1283  -5954       C  
ATOM    672  O   CYS C 501       8.364  46.922  41.015  1.00141.99           O  
ANISOU  672  O   CYS C 501    11333  27917  14699   2949   1064  -6450       O  
ATOM    673  CB  CYS C 501      11.316  46.160  41.265  1.00125.33           C  
ANISOU  673  CB  CYS C 501    11707  22896  13017   1378    693  -5101       C  
ATOM    674  SG  CYS C 501      11.313  45.816  43.069  1.00130.81           S  
ANISOU  674  SG  CYS C 501    12578  24081  13041    837   1360  -5182       S  
ATOM    675  N   GLU C 502       8.333  44.809  41.817  1.00143.68           N  
ANISOU  675  N   GLU C 502    11197  28749  14648    467   1965  -5992       N  
ATOM    676  CA  GLU C 502       7.037  44.987  42.452  1.00158.82           C  
ANISOU  676  CA  GLU C 502    11868  32396  16081    706   2533  -6696       C  
ATOM    677  C   GLU C 502       7.097  45.911  43.676  1.00162.87           C  
ANISOU  677  C   GLU C 502    12804  32921  16157   1579   2796  -7045       C  
ATOM    678  O   GLU C 502       6.058  46.301  44.214  1.00172.35           O  
ANISOU  678  O   GLU C 502    13005  35555  16926   2152   3248  -7728       O  
ATOM    679  CB  GLU C 502       6.393  43.628  42.804  1.00165.97           C  
ANISOU  679  CB  GLU C 502    12076  34340  16646  -1010   3306  -6665       C  
ATOM    680  CG  GLU C 502       7.044  42.810  43.925  1.00163.29           C  
ANISOU  680  CG  GLU C 502    12812  33317  15912  -2187   3876  -6141       C  
ATOM    681  CD  GLU C 502       6.172  41.623  44.341  1.00171.18           C  
ANISOU  681  CD  GLU C 502    13180  35460  16401  -3852   4793  -6233       C  
ATOM    682  OE1 GLU C 502       5.844  40.791  43.473  1.00165.75           O  
ANISOU  682  OE1 GLU C 502    12102  34971  15907  -4851   4807  -6166       O  
ATOM    683  OE2 GLU C 502       5.803  41.522  45.532  1.00179.76           O  
ANISOU  683  OE2 GLU C 502    14228  37247  16825  -4267   5543  -6403       O  
ATOM    684  N   PHE C 503       8.308  46.281  44.087  1.00154.97           N  
ANISOU  684  N   PHE C 503    13223  30432  15225   1696   2506  -6648       N  
ATOM    685  CA  PHE C 503       8.508  46.990  45.340  1.00158.10           C  
ANISOU  685  CA  PHE C 503    14227  30728  15114   2189   2775  -6946       C  
ATOM    686  C   PHE C 503       9.017  48.415  45.125  1.00154.88           C  
ANISOU  686  C   PHE C 503    14720  29265  14861   3562   2196  -7203       C  
ATOM    687  O   PHE C 503       8.488  49.349  45.721  1.00162.62           O  
ANISOU  687  O   PHE C 503    15697  30643  15447   4636   2398  -7851       O  
ATOM    688  CB  PHE C 503       9.459  46.188  46.236  1.00153.80           C  
ANISOU  688  CB  PHE C 503    14622  29536  14279   1016   2992  -6357       C  
ATOM    689  CG  PHE C 503       8.892  44.848  46.702  1.00160.31           C  
ANISOU  689  CG  PHE C 503    14934  31267  14712   -342   3739  -6129       C  
ATOM    690  CD1 PHE C 503       7.805  44.796  47.576  1.00173.62           C  
ANISOU  690  CD1 PHE C 503    15801  34418  15748   -504   4561  -6666       C  
ATOM    691  CD2 PHE C 503       9.460  43.643  46.289  1.00154.36           C  
ANISOU  691  CD2 PHE C 503    14643  29849  14156  -1483   3689  -5395       C  
ATOM    692  CE1 PHE C 503       7.285  43.567  48.020  1.00177.01           C  
ANISOU  692  CE1 PHE C 503    15922  35616  15716  -1982   5354  -6451       C  
ATOM    693  CE2 PHE C 503       8.941  42.410  46.732  1.00158.72           C  
ANISOU  693  CE2 PHE C 503    15054  31005  14249  -2833   4445  -5168       C  
ATOM    694  CZ  PHE C 503       7.855  42.380  47.600  1.00169.20           C  
ANISOU  694  CZ  PHE C 503    15611  33765  14911  -3178   5293  -5685       C  
ATOM    695  N   CYS C 504      10.030  48.589  44.282  1.00142.44           N  
ANISOU  695  N   CYS C 504    14000  26329  13793   3498   1544  -6732       N  
ATOM    696  CA  CYS C 504      10.532  49.925  43.984  1.00141.64           C  
ANISOU  696  CA  CYS C 504    14942  25084  13791   4559   1052  -6947       C  
ATOM    697  C   CYS C 504      10.559  50.115  42.484  1.00138.04           C  
ANISOU  697  C   CYS C 504    14475  24103  13872   4987    490  -6708       C  
ATOM    698  O   CYS C 504      10.236  49.197  41.730  1.00134.71           O  
ANISOU  698  O   CYS C 504    13200  24243  13740   4433    455  -6416       O  
ATOM    699  CB  CYS C 504      11.921  50.088  44.556  1.00133.82           C  
ANISOU  699  CB  CYS C 504    15195  22924  12725   3880    850  -6649       C  
ATOM    700  SG  CYS C 504      12.947  48.794  43.969  1.00124.92           S  
ANISOU  700  SG  CYS C 504    14052  21370  12041   2528    604  -5766       S  
ATOM    701  N   GLU C 505      10.963  51.305  42.055  1.00139.75           N  
ANISOU  701  N   GLU C 505    15792  23168  14140   5891     74  -6837       N  
ATOM    702  CA  GLU C 505      10.944  51.657  40.636  1.00138.06           C  
ANISOU  702  CA  GLU C 505    15793  22379  14283   6479   -453  -6620       C  
ATOM    703  C   GLU C 505      12.193  51.206  39.885  1.00125.29           C  
ANISOU  703  C   GLU C 505    14801  19699  13105   5367   -790  -5942       C  
ATOM    704  O   GLU C 505      12.365  51.541  38.719  1.00121.26           O  
ANISOU  704  O   GLU C 505    14711  18534  12829   5705  -1200  -5712       O  
ATOM    705  CB  GLU C 505      10.746  53.167  40.460  1.00147.46           C  
ANISOU  705  CB  GLU C 505    18124  22692  15212   8033   -688  -7035       C  
ATOM    706  CG  GLU C 505       9.651  53.782  41.341  1.00160.47           C  
ANISOU  706  CG  GLU C 505    19386  25252  16332   9374   -317  -7803       C  
ATOM    707  CD  GLU C 505       8.268  53.134  41.184  1.00168.80           C  
ANISOU  707  CD  GLU C 505    18483  28341  17311   9899   -108  -8099       C  
ATOM    708  OE1 GLU C 505       8.076  52.270  40.300  1.00163.11           O  
ANISOU  708  OE1 GLU C 505    16795  28245  16934   9278   -313  -7738       O  
ATOM    709  OE2 GLU C 505       7.356  53.509  41.958  1.00181.41           O  
ANISOU  709  OE2 GLU C 505    19478  31003  18445  10906    291  -8768       O  
ATOM    710  N   TYR C 506      13.066  50.460  40.550  1.00118.80           N  
ANISOU  710  N   TYR C 506    14056  18766  12317   4138   -616  -5629       N  
ATOM    711  CA  TYR C 506      14.166  49.806  39.861  1.00110.29           C  
ANISOU  711  CA  TYR C 506    13235  17046  11625   3155   -868  -5018       C  
ATOM    712  C   TYR C 506      13.592  48.902  38.821  1.00106.37           C  
ANISOU  712  C   TYR C 506    11861  17112  11441   2998   -931  -4755       C  
ATOM    713  O   TYR C 506      12.599  48.224  39.077  1.00106.52           O  
ANISOU  713  O   TYR C 506    10872  18254  11348   2933   -623  -4925       O  
ATOM    714  CB  TYR C 506      14.988  48.935  40.810  1.00109.14           C  
ANISOU  714  CB  TYR C 506    13063  17045  11358   2104   -663  -4733       C  
ATOM    715  CG  TYR C 506      15.787  47.828  40.120  1.00101.55           C  
ANISOU  715  CG  TYR C 506    11947  15883  10754   1255   -798  -4111       C  
ATOM    716  CD1 TYR C 506      17.116  48.025  39.759  1.00 98.71           C  
ANISOU  716  CD1 TYR C 506    12206  14743  10556    843  -1107  -3834       C  
ATOM    717  CD2 TYR C 506      15.214  46.581  39.846  1.00 98.65           C  
ANISOU  717  CD2 TYR C 506    10842  16144  10497    832   -564  -3860       C  
ATOM    718  CE1 TYR C 506      17.856  47.012  39.134  1.00 90.16           C  
ANISOU  718  CE1 TYR C 506    10952  13556   9749    257  -1194  -3319       C  
ATOM    719  CE2 TYR C 506      15.946  45.565  39.218  1.00 90.14           C  
ANISOU  719  CE2 TYR C 506     9815  14747   9685    184   -652  -3334       C  
ATOM    720  CZ  TYR C 506      17.264  45.789  38.870  1.00 87.50           C  
ANISOU  720  CZ  TYR C 506    10046  13682   9518     15   -972  -3065       C  
ATOM    721  OH  TYR C 506      17.999  44.797  38.264  1.00 79.06           O  
ANISOU  721  OH  TYR C 506     8998  12379   8663   -439  -1026  -2599       O  
ATOM    722  N   ALA C 507      14.260  48.857  37.673  1.00102.75           N  
ANISOU  722  N   ALA C 507    11804  15921  11317   2776  -1283  -4372       N  
ATOM    723  CA  ALA C 507      13.788  48.093  36.520  1.00100.74           C  
ANISOU  723  CA  ALA C 507    10894  16069  11313   2635  -1418  -4160       C  
ATOM    724  C   ALA C 507      14.952  47.392  35.831  1.00 94.28           C  
ANISOU  724  C   ALA C 507    10451  14565  10805   1759  -1541  -3618       C  
ATOM    725  O   ALA C 507      16.129  47.798  35.989  1.00 93.87           O  
ANISOU  725  O   ALA C 507    11169  13706  10790   1467  -1631  -3438       O  
ATOM    726  CB  ALA C 507      13.086  49.011  35.547  1.00105.76           C  
ANISOU  726  CB  ALA C 507    11644  16647  11894   3773  -1791  -4370       C  
ATOM    727  N   ALA C 508      14.621  46.356  35.055  1.00 90.69           N  
ANISOU  727  N   ALA C 508     9428  14511  10520   1324  -1527  -3429       N  
ATOM    728  CA  ALA C 508      15.643  45.492  34.455  1.00 83.09           C  
ANISOU  728  CA  ALA C 508     8759  13013   9799    565  -1548  -2960       C  
ATOM    729  C   ALA C 508      15.361  44.991  33.025  1.00 81.62           C  
ANISOU  729  C   ALA C 508     8381  12861   9771    460  -1745  -2841       C  
ATOM    730  O   ALA C 508      14.263  44.575  32.650  1.00 86.80           O  
ANISOU  730  O   ALA C 508     8335  14295  10349    475  -1742  -3070       O  
ATOM    731  CB  ALA C 508      15.897  44.319  35.358  1.00 80.77           C  
ANISOU  731  CB  ALA C 508     8294  12965   9430   -171  -1168  -2764       C  
ATOM    732  N   ALA C 509      16.411  45.038  32.236  1.00 77.42           N  
ANISOU  732  N   ALA C 509     8445  11571   9401    278  -1901  -2523       N  
ATOM    733  CA  ALA C 509      16.419  44.456  30.925  1.00 72.87           C  
ANISOU  733  CA  ALA C 509     7860  10905   8922     59  -2032  -2367       C  
ATOM    734  C   ALA C 509      16.527  42.923  30.951  1.00 69.90           C  
ANISOU  734  C   ALA C 509     7260  10684   8615   -729  -1725  -2208       C  
ATOM    735  O   ALA C 509      16.233  42.317  29.966  1.00 75.37           O  
ANISOU  735  O   ALA C 509     7865  11458   9313   -979  -1784  -2212       O  
ATOM    736  CB  ALA C 509      17.572  45.045  30.112  1.00 66.90           C  
ANISOU  736  CB  ALA C 509     7865   9316   8237     78  -2194  -2101       C  
ATOM    737  N   GLN C 510      16.924  42.276  32.040  1.00 69.91           N  
ANISOU  737  N   GLN C 510     7312  10666   8586  -1098  -1402  -2071       N  
ATOM    738  CA  GLN C 510      17.104  40.802  32.019  1.00 70.12           C  
ANISOU  738  CA  GLN C 510     7492  10562   8589  -1749  -1083  -1856       C  
ATOM    739  C   GLN C 510      16.619  40.111  33.317  1.00 73.87           C  
ANISOU  739  C   GLN C 510     7869  11377   8820  -2155   -675  -1860       C  
ATOM    740  O   GLN C 510      16.712  40.674  34.394  1.00 78.16           O  
ANISOU  740  O   GLN C 510     8359  12102   9237  -1902   -635  -1895       O  
ATOM    741  CB  GLN C 510      18.586  40.462  31.724  1.00 66.41           C  
ANISOU  741  CB  GLN C 510     7590   9410   8231  -1705  -1094  -1480       C  
ATOM    742  CG  GLN C 510      19.019  40.695  30.251  1.00 63.87           C  
ANISOU  742  CG  GLN C 510     7451   8763   8054  -1598  -1309  -1448       C  
ATOM    743  CD  GLN C 510      20.187  39.793  29.779  1.00 69.27           C  
ANISOU  743  CD  GLN C 510     8563   8982   8775  -1683  -1143  -1162       C  
ATOM    744  OE1 GLN C 510      20.936  40.184  28.889  1.00 72.71           O  
ANISOU  744  OE1 GLN C 510     9139   9208   9280  -1547  -1250  -1104       O  
ATOM    745  NE2 GLN C 510      20.332  38.588  30.362  1.00 68.54           N  
ANISOU  745  NE2 GLN C 510     8757   8721   8563  -1854   -844   -988       N  
ATOM    746  N   LYS C 511      16.100  38.896  33.239  1.00 78.95           N  
ANISOU  746  N   LYS C 511     8613  12066   9317  -2872   -327  -1839       N  
ATOM    747  CA  LYS C 511      15.473  38.322  34.435  1.00 84.42           C  
ANISOU  747  CA  LYS C 511     9278  13126   9673  -3399    142  -1864       C  
ATOM    748  C   LYS C 511      16.515  38.231  35.523  1.00 79.66           C  
ANISOU  748  C   LYS C 511     9293  12063   8910  -3088    218  -1457       C  
ATOM    749  O   LYS C 511      16.284  38.694  36.623  1.00 82.60           O  
ANISOU  749  O   LYS C 511     9483  12850   9053  -2964    329  -1541       O  
ATOM    750  CB  LYS C 511      14.794  36.944  34.198  1.00 90.33           C  
ANISOU  750  CB  LYS C 511    10301  13833  10186  -4480    609  -1894       C  
ATOM    751  CG  LYS C 511      13.403  37.017  33.527  1.00101.74           C  
ANISOU  751  CG  LYS C 511    10788  16281  11588  -5040    610  -2471       C  
ATOM    752  CD  LYS C 511      12.455  35.816  33.894  1.00120.30           C  
ANISOU  752  CD  LYS C 511    13213  18978  13517  -6465   1270  -2655       C  
ATOM    753  CE  LYS C 511      11.257  35.638  32.864  1.00129.18           C  
ANISOU  753  CE  LYS C 511    13390  21122  14570  -7233   1186  -3282       C  
ATOM    754  NZ  LYS C 511      10.082  34.836  33.379  1.00131.37           N  
ANISOU  754  NZ  LYS C 511    13252  22287  14374  -8742   1848  -3679       N  
ATOM    755  N   THR C 512      17.675  37.672  35.224  1.00 75.82           N  
ANISOU  755  N   THR C 512     9483  10841   8485  -2869    132  -1059       N  
ATOM    756  CA  THR C 512      18.610  37.353  36.300  1.00 76.75           C  
ANISOU  756  CA  THR C 512    10159  10695   8307  -2545    185   -663       C  
ATOM    757  C   THR C 512      18.785  38.569  37.189  1.00 75.11           C  
ANISOU  757  C   THR C 512     9505  10992   8041  -2127    -59   -838       C  
ATOM    758  O   THR C 512      18.780  38.483  38.408  1.00 83.12           O  
ANISOU  758  O   THR C 512    10716  12220   8644  -2125     98   -734       O  
ATOM    759  CB  THR C 512      19.972  36.897  35.757  1.00 77.63           C  
ANISOU  759  CB  THR C 512    10754  10226   8517  -2030    -17   -315       C  
ATOM    760  OG1 THR C 512      19.823  35.595  35.162  1.00 81.16           O  
ANISOU  760  OG1 THR C 512    11935  10035   8867  -2370    310   -137       O  
ATOM    761  CG2 THR C 512      21.040  36.868  36.881  1.00 66.11           C  
ANISOU  761  CG2 THR C 512     9569   8836   6712  -1443   -163     13       C  
ATOM    762  N   SER C 513      18.897  39.733  36.595  1.00 71.60           N  
ANISOU  762  N   SER C 513     8593  10685   7926  -1807   -417  -1126       N  
ATOM    763  CA  SER C 513      19.120  40.929  37.402  1.00 71.70           C  
ANISOU  763  CA  SER C 513     8409  10995   7837  -1467   -628  -1351       C  
ATOM    764  C   SER C 513      17.966  41.167  38.371  1.00 72.65           C  
ANISOU  764  C   SER C 513     8268  11679   7656  -1588   -335  -1644       C  
ATOM    765  O   SER C 513      18.170  41.376  39.572  1.00 83.21           O  
ANISOU  765  O   SER C 513     9758  13244   8613  -1506   -266  -1650       O  
ATOM    766  CB  SER C 513      19.310  42.136  36.494  1.00 70.52           C  
ANISOU  766  CB  SER C 513     8079  10691   8023  -1182   -980  -1610       C  
ATOM    767  OG  SER C 513      18.053  42.538  35.991  1.00 85.60           O  
ANISOU  767  OG  SER C 513     9631  12859  10034  -1103   -944  -1937       O  
ATOM    768  N   LEU C 514      16.741  41.149  37.888  1.00 69.89           N  
ANISOU  768  N   LEU C 514     7446  11708   7399  -1774   -156  -1937       N  
ATOM    769  CA  LEU C 514      15.640  41.313  38.832  1.00 78.31           C  
ANISOU  769  CA  LEU C 514     8105  13531   8120  -1896    211  -2271       C  
ATOM    770  C   LEU C 514      15.710  40.228  39.899  1.00 82.16           C  
ANISOU  770  C   LEU C 514     9060  14035   8123  -2469    678  -1938       C  
ATOM    771  O   LEU C 514      15.490  40.507  41.073  1.00 88.28           O  
ANISOU  771  O   LEU C 514     9850  15223   8469  -2428    906  -2055       O  
ATOM    772  CB  LEU C 514      14.269  41.248  38.146  1.00 84.52           C  
ANISOU  772  CB  LEU C 514     8099  15025   8991  -2101    365  -2674       C  
ATOM    773  CG  LEU C 514      13.047  41.473  39.027  1.00 90.62           C  
ANISOU  773  CG  LEU C 514     8174  16874   9384  -2183    793  -3136       C  
ATOM    774  CD1 LEU C 514      13.147  42.863  39.643  1.00 88.01           C  
ANISOU  774  CD1 LEU C 514     7822  16643   8976  -1220    576  -3460       C  
ATOM    775  CD2 LEU C 514      11.723  41.299  38.251  1.00 98.30           C  
ANISOU  775  CD2 LEU C 514     8119  18836  10394  -2439    898  -3588       C  
ATOM    776  N   ARG C 515      15.995  38.988  39.503  1.00 83.54           N  
ANISOU  776  N   ARG C 515     9766  13695   8279  -2974    853  -1523       N  
ATOM    777  CA  ARG C 515      16.071  37.909  40.483  1.00 89.95           C  
ANISOU  777  CA  ARG C 515    11343  14313   8523  -3464   1320  -1121       C  
ATOM    778  C   ARG C 515      17.091  38.288  41.528  1.00 88.18           C  
ANISOU  778  C   ARG C 515    11544  13990   7971  -2853   1064   -869       C  
ATOM    779  O   ARG C 515      16.804  38.245  42.725  1.00 95.20           O  
ANISOU  779  O   ARG C 515    12647  15242   8284  -3003   1373   -845       O  
ATOM    780  CB  ARG C 515      16.400  36.547  39.862  1.00 93.23           C  
ANISOU  780  CB  ARG C 515    12605  13900   8916  -3905   1507   -681       C  
ATOM    781  CG  ARG C 515      17.010  35.515  40.861  1.00105.51           C  
ANISOU  781  CG  ARG C 515    15408  14862   9821  -3938   1792    -64       C  
ATOM    782  CD  ARG C 515      16.937  34.034  40.369  1.00118.84           C  
ANISOU  782  CD  ARG C 515    18224  15622  11306  -4572   2221    299       C  
ATOM    783  NE  ARG C 515      17.401  33.857  38.987  1.00118.74           N  
ANISOU  783  NE  ARG C 515    18177  15094  11844  -4320   1905    253       N  
ATOM    784  CZ  ARG C 515      18.675  33.940  38.579  1.00122.24           C  
ANISOU  784  CZ  ARG C 515    18819  15115  12511  -3321   1419    515       C  
ATOM    785  NH1 ARG C 515      19.666  34.192  39.441  1.00119.90           N  
ANISOU  785  NH1 ARG C 515    18700  14914  11942  -2455   1108    832       N  
ATOM    786  NH2 ARG C 515      18.966  33.787  37.283  1.00121.83           N  
ANISOU  786  NH2 ARG C 515    18696  14690  12904  -3209   1241    405       N  
ATOM    787  N   TYR C 516      18.270  38.699  41.100  1.00 81.32           N  
ANISOU  787  N   TYR C 516    10731  12772   7395  -2227    508   -737       N  
ATOM    788  CA  TYR C 516      19.235  39.208  42.083  1.00 84.89           C  
ANISOU  788  CA  TYR C 516    11364  13395   7496  -1723    178   -642       C  
ATOM    789  C   TYR C 516      18.637  40.303  42.959  1.00 86.25           C  
ANISOU  789  C   TYR C 516    11150  14185   7437  -1690    237  -1136       C  
ATOM    790  O   TYR C 516      18.600  40.149  44.191  1.00 94.78           O  
ANISOU  790  O   TYR C 516    12570  15573   7867  -1731    427  -1047       O  
ATOM    791  CB  TYR C 516      20.512  39.731  41.421  1.00 81.49           C  
ANISOU  791  CB  TYR C 516    10754  12778   7429  -1233   -407   -621       C  
ATOM    792  CG  TYR C 516      21.526  40.325  42.375  1.00 81.61           C  
ANISOU  792  CG  TYR C 516    10777  13181   7049   -876   -805   -654       C  
ATOM    793  CD1 TYR C 516      22.619  39.582  42.803  1.00 94.59           C  
ANISOU  793  CD1 TYR C 516    12765  14884   8289   -461  -1045   -208       C  
ATOM    794  CD2 TYR C 516      21.405  41.639  42.835  1.00 88.61           C  
ANISOU  794  CD2 TYR C 516    11360  14412   7898   -905   -970  -1177       C  
ATOM    795  CE1 TYR C 516      23.566  40.118  43.680  1.00100.52           C  
ANISOU  795  CE1 TYR C 516    13371  16232   8589   -173  -1491   -303       C  
ATOM    796  CE2 TYR C 516      22.339  42.187  43.725  1.00 92.91           C  
ANISOU  796  CE2 TYR C 516    11928  15374   7999   -757  -1349  -1299       C  
ATOM    797  CZ  TYR C 516      23.422  41.421  44.149  1.00100.22           C  
ANISOU  797  CZ  TYR C 516    13010  16559   8510   -437  -1637   -874       C  
ATOM    798  OH  TYR C 516      24.368  41.932  45.024  1.00102.56           O  
ANISOU  798  OH  TYR C 516    13182  17503   8283   -319  -2092  -1047       O  
ATOM    799  N   HIS C 517      18.192  41.404  42.349  1.00 81.15           N  
ANISOU  799  N   HIS C 517     9930  13672   7230  -1524     79  -1646       N  
ATOM    800  CA  HIS C 517      17.697  42.553  43.149  1.00 85.35           C  
ANISOU  800  CA  HIS C 517    10245  14669   7516  -1284    118  -2183       C  
ATOM    801  C   HIS C 517      16.681  42.065  44.163  1.00 91.10           C  
ANISOU  801  C   HIS C 517    10935  15999   7682  -1614    729  -2255       C  
ATOM    802  O   HIS C 517      16.829  42.302  45.354  1.00 99.84           O  
ANISOU  802  O   HIS C 517    12326  17408   8199  -1548    825  -2332       O  
ATOM    803  CB  HIS C 517      17.110  43.629  42.241  1.00 85.41           C  
ANISOU  803  CB  HIS C 517     9813  14637   8004   -925    -42  -2671       C  
ATOM    804  CG  HIS C 517      16.233  44.628  42.925  1.00 89.44           C  
ANISOU  804  CG  HIS C 517    10109  15629   8243   -532    147  -3270       C  
ATOM    805  ND1 HIS C 517      16.605  45.944  43.085  1.00 89.82           N  
ANISOU  805  ND1 HIS C 517    10486  15373   8269    -49   -153  -3670       N  
ATOM    806  CD2 HIS C 517      14.965  44.532  43.408  1.00 99.47           C  
ANISOU  806  CD2 HIS C 517    10876  17682   9234   -523    647  -3600       C  
ATOM    807  CE1 HIS C 517      15.619  46.607  43.673  1.00100.15           C  
ANISOU  807  CE1 HIS C 517    11604  17164   9285    403    135  -4207       C  
ATOM    808  NE2 HIS C 517      14.612  45.774  43.882  1.00 94.21           N  
ANISOU  808  NE2 HIS C 517    10228  17190   8378    154    624  -4186       N  
ATOM    809  N   LEU C 518      15.676  41.337  43.710  1.00 92.43           N  
ANISOU  809  N   LEU C 518    10771  16405   7944  -2091   1174  -2247       N  
ATOM    810  CA  LEU C 518      14.695  40.787  44.635  1.00104.87           C  
ANISOU  810  CA  LEU C 518    12281  18645   8922  -2653   1880  -2324       C  
ATOM    811  C   LEU C 518      15.356  40.114  45.832  1.00107.80           C  
ANISOU  811  C   LEU C 518    13584  18816   8559  -2850   2044  -1823       C  
ATOM    812  O   LEU C 518      14.991  40.374  46.972  1.00114.88           O  
ANISOU  812  O   LEU C 518    14558  20270   8822  -2897   2385  -2013       O  
ATOM    813  CB  LEU C 518      13.738  39.798  43.927  1.00110.55           C  
ANISOU  813  CB  LEU C 518    12665  19574   9766  -3491   2355  -2293       C  
ATOM    814  CG  LEU C 518      12.612  40.424  43.079  1.00113.10           C  
ANISOU  814  CG  LEU C 518    11798  20682  10493  -3359   2359  -2942       C  
ATOM    815  CD1 LEU C 518      11.747  39.357  42.422  1.00122.16           C  
ANISOU  815  CD1 LEU C 518    12591  22168  11657  -4412   2796  -2958       C  
ATOM    816  CD2 LEU C 518      11.746  41.391  43.923  1.00116.32           C  
ANISOU  816  CD2 LEU C 518    11494  22149  10553  -2902   2641  -3587       C  
ATOM    817  N   GLU C 519      16.339  39.264  45.583  1.00107.04           N  
ANISOU  817  N   GLU C 519    14233  17968   8469  -2844   1787  -1191       N  
ATOM    818  CA  GLU C 519      16.890  38.477  46.663  1.00115.29           C  
ANISOU  818  CA  GLU C 519    16277  18823   8705  -2902   1928   -633       C  
ATOM    819  C   GLU C 519      17.619  39.368  47.623  1.00116.88           C  
ANISOU  819  C   GLU C 519    16522  19384   8502  -2294   1491   -795       C  
ATOM    820  O   GLU C 519      17.339  39.373  48.831  1.00127.00           O  
ANISOU  820  O   GLU C 519    18160  21113   8981  -2424   1814   -809       O  
ATOM    821  CB  GLU C 519      17.839  37.392  46.158  1.00116.46           C  
ANISOU  821  CB  GLU C 519    17257  18096   8895  -2725   1687     61       C  
ATOM    822  CG  GLU C 519      18.206  36.343  47.232  1.00130.95           C  
ANISOU  822  CG  GLU C 519    20391  19618   9744  -2731   1935    747       C  
ATOM    823  CD  GLU C 519      16.984  35.736  47.964  1.00148.11           C  
ANISOU  823  CD  GLU C 519    23048  21984  11245  -3756   2883    789       C  
ATOM    824  OE1 GLU C 519      15.843  35.779  47.440  1.00153.81           O  
ANISOU  824  OE1 GLU C 519    23088  23033  12319  -4587   3401    348       O  
ATOM    825  OE2 GLU C 519      17.167  35.209  49.084  1.00159.14           O  
ANISOU  825  OE2 GLU C 519    25492  23304  11669  -3759   3120   1254       O  
ATOM    826  N   ARG C 520      18.547  40.137  47.082  1.00108.55           N  
ANISOU  826  N   ARG C 520    15130  18176   7938  -1744    791   -962       N  
ATOM    827  CA  ARG C 520      19.342  41.011  47.905  1.00106.57           C  
ANISOU  827  CA  ARG C 520    14916  18278   7300  -1339    317  -1202       C  
ATOM    828  C   ARG C 520      18.573  42.150  48.564  1.00107.19           C  
ANISOU  828  C   ARG C 520    14685  18875   7167  -1358    543  -1921       C  
ATOM    829  O   ARG C 520      18.894  42.472  49.673  1.00114.53           O  
ANISOU  829  O   ARG C 520    15945  20188   7381  -1254    448  -2043       O  
ATOM    830  CB  ARG C 520      20.488  41.586  47.102  1.00101.96           C  
ANISOU  830  CB  ARG C 520    14011  17464   7267   -997   -390  -1290       C  
ATOM    831  CG  ARG C 520      21.084  42.779  47.739  1.00108.29           C  
ANISOU  831  CG  ARG C 520    14701  18647   7798   -866   -816  -1802       C  
ATOM    832  CD  ARG C 520      21.654  42.408  49.044  1.00127.25           C  
ANISOU  832  CD  ARG C 520    17565  21555   9231   -726   -985  -1569       C  
ATOM    833  NE  ARG C 520      23.080  42.580  49.016  1.00131.95           N  
ANISOU  833  NE  ARG C 520    17981  22432   9720   -488  -1718  -1520       N  
ATOM    834  CZ  ARG C 520      23.716  43.596  49.580  1.00145.23           C  
ANISOU  834  CZ  ARG C 520    19513  24602  11066   -611  -2156  -2062       C  
ATOM    835  NH1 ARG C 520      23.077  44.560  50.252  1.00145.20           N  
ANISOU  835  NH1 ARG C 520    19696  24697  10777   -853  -1940  -2688       N  
ATOM    836  NH2 ARG C 520      25.020  43.628  49.482  1.00154.81           N  
ANISOU  836  NH2 ARG C 520    20379  26280  12164   -500  -2802  -2027       N  
ATOM    837  N   HIS C 521      17.585  42.779  47.933  1.00105.39           N  
ANISOU  837  N   HIS C 521    13868  18716   7459  -1373    810  -2427       N  
ATOM    838  CA  HIS C 521      16.904  43.909  48.622  1.00112.62           C  
ANISOU  838  CA  HIS C 521    14595  20113   8082  -1130   1022  -3159       C  
ATOM    839  C   HIS C 521      15.478  43.709  49.108  1.00120.98           C  
ANISOU  839  C   HIS C 521    15285  21891   8792  -1337   1829  -3446       C  
ATOM    840  O   HIS C 521      14.876  44.682  49.539  1.00126.09           O  
ANISOU  840  O   HIS C 521    15697  22961   9250   -939   2017  -4119       O  
ATOM    841  CB  HIS C 521      16.888  45.162  47.760  1.00107.99           C  
ANISOU  841  CB  HIS C 521    13711  19179   8142   -668    669  -3707       C  
ATOM    842  CG  HIS C 521      18.231  45.561  47.278  1.00103.84           C  
ANISOU  842  CG  HIS C 521    13471  18070   7914   -637    -21  -3579       C  
ATOM    843  ND1 HIS C 521      18.751  46.819  47.477  1.00109.54           N  
ANISOU  843  ND1 HIS C 521    14514  18551   8556   -471   -365  -4108       N  
ATOM    844  CD2 HIS C 521      19.170  44.861  46.608  1.00101.46           C  
ANISOU  844  CD2 HIS C 521    13178  17441   7932   -815   -378  -3033       C  
ATOM    845  CE1 HIS C 521      19.954  46.881  46.934  1.00110.92           C  
ANISOU  845  CE1 HIS C 521    14776  18375   8995   -694   -889  -3898       C  
ATOM    846  NE2 HIS C 521      20.232  45.704  46.399  1.00101.59           N  
ANISOU  846  NE2 HIS C 521    13336  17196   8067   -812   -913  -3250       N  
ATOM    847  N   HIS C 522      14.930  42.494  49.043  1.00126.05           N  
ANISOU  847  N   HIS C 522    15901  22697   9295  -1975   2348  -3007       N  
ATOM    848  CA  HIS C 522      13.507  42.279  49.378  1.00134.17           C  
ANISOU  848  CA  HIS C 522    16354  24619  10006  -2397   3198  -3359       C  
ATOM    849  C   HIS C 522      13.215  40.855  49.890  1.00140.42           C  
ANISOU  849  C   HIS C 522    17682  25496  10174  -3400   3867  -2768       C  
ATOM    850  O   HIS C 522      13.996  40.266  50.636  1.00142.86           O  
ANISOU  850  O   HIS C 522    19021  25392   9870  -3516   3789  -2186       O  
ATOM    851  CB  HIS C 522      12.599  42.573  48.155  1.00130.91           C  
ANISOU  851  CB  HIS C 522    14879  24506  10355  -2265   3231  -3784       C  
ATOM    852  CG  HIS C 522      12.795  43.928  47.514  1.00121.64           C  
ANISOU  852  CG  HIS C 522    13409  23064   9744  -1244   2622  -4287       C  
ATOM    853  ND1 HIS C 522      12.558  45.115  48.173  1.00121.67           N  
ANISOU  853  ND1 HIS C 522    13400  23380   9450   -493   2642  -4935       N  
ATOM    854  CD2 HIS C 522      13.140  44.272  46.246  1.00117.72           C  
ANISOU  854  CD2 HIS C 522    12765  21952  10013   -874   2046  -4241       C  
ATOM    855  CE1 HIS C 522      12.783  46.129  47.355  1.00118.62           C  
ANISOU  855  CE1 HIS C 522    13011  22450   9609    286   2097  -5228       C  
ATOM    856  NE2 HIS C 522      13.130  45.645  46.176  1.00112.92           N  
ANISOU  856  NE2 HIS C 522    12176  21202   9527     49   1733  -4797       N  
TER     857      HIS C 522                                                      
HETATM  858 ZN    ZN C 601      12.745  46.786  44.170  1.00129.07          ZN  
ANISOU  858 ZN    ZN C 601    13777  22740  12524   1147   1074  -5142      ZN  
HETATM  859 ZN    ZN C 602      25.492  45.259  21.272  1.00 86.96          ZN  
ANISOU  859 ZN    ZN C 602    13740   9475   9825  -2762   -882   -623      ZN  
CONECT  433  859                                                                
CONECT  457  859                                                                
CONECT  575  859                                                                
CONECT  611  859                                                                
CONECT  674  858                                                                
CONECT  700  858                                                                
CONECT  808  858                                                                
CONECT  856  858                                                                
CONECT  858  674  700  808  856                                                 
CONECT  859  433  457  575  611                                                 
MASTER      466    0    2    2    2    0    2    6  857    2   10    7          
END

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Related entries of code: 4f2j

Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code	Check Database	Protein Sequence Similarity
4is1	RCSB PDB PDBbind	20aa, >4IS1_2\|Chain... at 90%
Complexes with the same small molecule ligand
PDB Code	Check Database	Ligand Name
No complexes with the same small molecule ligand are found!

Entry Information

PDB ID	4f2j
Complex Type	Protein-Nucleic Acid
PDBbind Subset	general set
Protein Name	20-mer DNA
Ligand Name	Zinc finger protein 217
EC.Number	E.C.-.-.-.-
Resolution	2.64(Å)
Affinity (Kd/Ki/IC50)	Kd=25nM
Release Year	2013
Protein/NA Sequence	Check fasta file
Primary Reference	(2013) J.Biol.Chem. Vol. 288: pp. 10616-10627

Links to External Databases

RCSB PDB	The mother database
PDBsum	Enhanced annotations on PDB entries
Pubchem	Comprehensive collection of chemical and biological data
UniProtKB AC	UniProt accession number (AC): O75362
Entrez Gene ID	NCBI Entrez Gene ID: 7764
ASD	Information of known allosteric effects of PDB entries

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