Browse entries in the PDBbind-CN Database
HEADER DNA BINDING PROTEIN/DNA 15-MAY-12 4F6N TITLE CRYSTAL STRUCTURE OF KAISO ZINC FINGER DNA BINDING PROTEIN IN COMPLEX TITLE 2 WITH METHYLATED CPG SITE DNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTIONAL REGULATOR KAISO; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: ZINC FINGER DNA BINDING DOMAIN; COMPND 5 SYNONYM: ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 33; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM) COMPND 9 P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'); COMPND 10 CHAIN: D; COMPND 11 ENGINEERED: YES; COMPND 12 OTHER_DETAILS: MEECAD DNA STRAND 1; COMPND 13 MOL_ID: 3; COMPND 14 MOLECULE: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM) COMPND 15 P*GP*GP*TP*GP*AP*CP*AP*C)-3'); COMPND 16 CHAIN: E; COMPND 17 ENGINEERED: YES; COMPND 18 OTHER_DETAILS: MEECAD DNA STRAND 2 SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: ZBTB33, KAISO, ZNF348; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3)[DNAY]; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET21D; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 14 ORGANISM_TAXID: 9606; SOURCE 15 OTHER_DETAILS: THIS SEQUENCE OCCURS IN HUMANS; SOURCE 16 MOL_ID: 3; SOURCE 17 SYNTHETIC: YES; SOURCE 18 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 19 ORGANISM_TAXID: 9606; SOURCE 20 OTHER_DETAILS: THIS SEQUENCE OCCURS IN HUMANS KEYWDS ZINC FINGER, PROTEIN-DNA COMPLEX, DOUBLE HELIX, DNA BINDING, DNA, DNA KEYWDS 2 BINDING PROTEIN-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR B.A.BUCK-KOEHNTOP,R.L.STANFIELD,D.C.EKIERT,M.A.MARTINEZ-YAMOUT, AUTHOR 2 H.J.DYSON,I.A.WILSON,P.E.WRIGHT REVDAT 3 03-OCT-12 4F6N 1 JRNL REVDAT 2 26-SEP-12 4F6N 1 JRNL REVDAT 1 05-SEP-12 4F6N 0 JRNL AUTH B.A.BUCK-KOEHNTOP,R.L.STANFIELD,D.C.EKIERT, JRNL AUTH 2 M.A.MARTINEZ-YAMOUT,H.J.DYSON,I.A.WILSON,P.E.WRIGHT JRNL TITL MOLECULAR BASIS FOR RECOGNITION OF METHYLATED AND SPECIFIC JRNL TITL 2 DNA SEQUENCES BY THE ZINC FINGER PROTEIN KAISO. JRNL REF PROC.NATL.ACAD.SCI.USA V. 109 15229 2012 JRNL REFN ISSN 0027-8424 JRNL PMID 22949637 JRNL DOI 10.1073/PNAS.1213726109 REMARK 2 REMARK 2 RESOLUTION. 2.80 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.5.0109 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.80 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 65.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 99.3 REMARK 3 NUMBER OF REFLECTIONS : 11779 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.230 REMARK 3 R VALUE (WORKING SET) : 0.228 REMARK 3 FREE R VALUE : 0.261 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.700 REMARK 3 FREE R VALUE TEST SET COUNT : 558 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.80 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.87 REMARK 3 REFLECTION IN BIN (WORKING SET) : 763 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 94.83 REMARK 3 BIN R VALUE (WORKING SET) : 0.3890 REMARK 3 BIN FREE R VALUE SET COUNT : 44 REMARK 3 BIN FREE R VALUE : 0.4580 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1020 REMARK 3 NUCLEIC ACID ATOMS : 761 REMARK 3 HETEROGEN ATOMS : 15 REMARK 3 SOLVENT ATOMS : 15 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 72.00 REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.440 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.300 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.228 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): NULL REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.926 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.902 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1965 ; 0.011 ; 0.021 REMARK 3 BOND LENGTHS OTHERS (A): NULL ; NULL ; NULL REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 2755 ; 1.579 ; 2.435 REMARK 3 BOND ANGLES OTHERS (DEGREES): NULL ; NULL ; NULL REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 119 ; 6.364 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 55 ;30.590 ;21.273 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 185 ;18.155 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 11 ;18.264 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): NULL ; NULL ; NULL REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1201 ; 0.004 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 2 REMARK 3 REMARK 3 TLS GROUP : 1 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : A 481 A 600 REMARK 3 ORIGIN FOR THE GROUP (A): -14.6827 -27.2737 24.1289 REMARK 3 T TENSOR REMARK 3 T11: 0.1805 T22: 0.1884 REMARK 3 T33: 0.2151 T12: 0.0506 REMARK 3 T13: 0.0302 T23: 0.0050 REMARK 3 L TENSOR REMARK 3 L11: 2.1190 L22: 8.7494 REMARK 3 L33: 1.8565 L12: 0.3415 REMARK 3 L13: 0.6568 L23: 0.6478 REMARK 3 S TENSOR REMARK 3 S11: -0.0354 S12: -0.0430 S13: 0.3029 REMARK 3 S21: 0.5372 S22: 0.1238 S23: -0.2909 REMARK 3 S31: -0.4351 S32: 0.0419 S33: -0.0885 REMARK 3 REMARK 3 TLS GROUP : 2 REMARK 3 NUMBER OF COMPONENTS GROUP : 2 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : D 1 D 19 REMARK 3 RESIDUE RANGE : E 21 E 38 REMARK 3 ORIGIN FOR THE GROUP (A): -16.8148 -23.0558 29.4536 REMARK 3 T TENSOR REMARK 3 T11: 0.4464 T22: 0.3147 REMARK 3 T33: 0.2965 T12: 0.0321 REMARK 3 T13: 0.0665 T23: -0.0183 REMARK 3 L TENSOR REMARK 3 L11: 4.2832 L22: 5.1503 REMARK 3 L33: 7.5288 L12: 0.4622 REMARK 3 L13: -1.4029 L23: 0.1268 REMARK 3 S TENSOR REMARK 3 S11: 0.1324 S12: -0.8271 S13: 0.2844 REMARK 3 S21: 0.8652 S22: 0.0594 S23: -0.1733 REMARK 3 S31: -1.0375 S32: 0.3513 S33: -0.1918 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : BABINET MODEL WITH MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.40 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 4F6N COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 24-MAY-12. REMARK 100 THE RCSB ID CODE IS RCSB072521. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 25-MAY-10 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 6.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRL REMARK 200 BEAMLINE : BL9-2 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9795 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : MARMOSAIC 325 MM CCD REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 11780 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.800 REMARK 200 RESOLUTION RANGE LOW (A) : 65.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.3 REMARK 200 DATA REDUNDANCY : 7.360 REMARK 200 R MERGE (I) : 0.08700 REMARK 200 R SYM (I) : 0.08700 REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 23.0000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.80 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.85 REMARK 200 COMPLETENESS FOR SHELL (%) : 92.4 REMARK 200 DATA REDUNDANCY IN SHELL : 7.20 REMARK 200 R MERGE FOR SHELL (I) : 0.58100 REMARK 200 R SYM FOR SHELL (I) : 0.58100 REMARK 200 <I/SIGMA(I)> FOR SHELL : 3.300 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: KAISO FROM COMPLEX WITH KAISO BINDING SITE PROTEIN REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 70.58 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 4.18 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 1M NACL, 0.1M SODIUM CACODYLATE, 10% REMARK 280 GLYCEROL, 30% PEG 600, PH 6.5, VAPOR DIFFUSION, SITTING DROP, REMARK 280 TEMPERATURE 277K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: F 2 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z REMARK 290 3555 -X,Y,-Z REMARK 290 4555 X,-Y,-Z REMARK 290 5555 X,Y+1/2,Z+1/2 REMARK 290 6555 -X,-Y+1/2,Z+1/2 REMARK 290 7555 -X,Y+1/2,-Z+1/2 REMARK 290 8555 X,-Y+1/2,-Z+1/2 REMARK 290 9555 X+1/2,Y,Z+1/2 REMARK 290 10555 -X+1/2,-Y,Z+1/2 REMARK 290 11555 -X+1/2,Y,-Z+1/2 REMARK 290 12555 X+1/2,-Y,-Z+1/2 REMARK 290 13555 X+1/2,Y+1/2,Z REMARK 290 14555 -X+1/2,-Y+1/2,Z REMARK 290 15555 -X+1/2,Y+1/2,-Z REMARK 290 16555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 91.70100 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 115.06900 REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 91.70100 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 115.06900 REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 91.70100 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 115.06900 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 91.70100 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 115.06900 REMARK 290 SMTRY1 9 1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 9 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 9 0.000000 0.000000 1.000000 115.06900 REMARK 290 SMTRY1 10 -1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 10 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 10 0.000000 0.000000 1.000000 115.06900 REMARK 290 SMTRY1 11 -1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 11 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 11 0.000000 0.000000 -1.000000 115.06900 REMARK 290 SMTRY1 12 1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 12 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 12 0.000000 0.000000 -1.000000 115.06900 REMARK 290 SMTRY1 13 1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 13 0.000000 1.000000 0.000000 91.70100 REMARK 290 SMTRY3 13 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 14 -1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 14 0.000000 -1.000000 0.000000 91.70100 REMARK 290 SMTRY3 14 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 15 -1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 15 0.000000 1.000000 0.000000 91.70100 REMARK 290 SMTRY3 15 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 16 1.000000 0.000000 0.000000 22.02450 REMARK 290 SMTRY2 16 0.000000 -1.000000 0.000000 91.70100 REMARK 290 SMTRY3 16 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 7950 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11780 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: 5.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, D, E REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 HOH A 802 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ALA A 472 REMARK 465 ASN A 473 REMARK 465 LYS A 474 REMARK 465 ARG A 475 REMARK 465 MET A 476 REMARK 465 LYS A 477 REMARK 465 VAL A 478 REMARK 465 LYS A 479 REMARK 465 HIS A 480 REMARK 465 SER A 601 REMARK 465 ASP A 602 REMARK 465 ARG A 603 REMARK 465 SER A 604 REMARK 465 DC E 20 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 DG D 19 C2 DG D 19 N3 0.171 REMARK 500 DG D 19 C2 DG D 19 N2 0.157 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DA D 6 O4' - C1' - N9 ANGL. DEV. = -4.6 DEGREES REMARK 500 DC D 7 O4' - C1' - N1 ANGL. DEV. = -5.0 DEGREES REMARK 500 DT D 12 C3' - C2' - C1' ANGL. DEV. = -4.8 DEGREES REMARK 500 DT D 12 O4' - C1' - N1 ANGL. DEV. = 2.6 DEGREES REMARK 500 DC D 13 O4' - C1' - N1 ANGL. DEV. = 3.3 DEGREES REMARK 500 DA D 17 O4' - C1' - N9 ANGL. DEV. = 1.8 DEGREES REMARK 500 DC D 18 O4' - C1' - N1 ANGL. DEV. = 2.5 DEGREES REMARK 500 DG D 19 N1 - C2 - N3 ANGL. DEV. = -7.5 DEGREES REMARK 500 DG D 19 N1 - C2 - N2 ANGL. DEV. = -14.0 DEGREES REMARK 500 DG D 19 N3 - C2 - N2 ANGL. DEV. = 21.6 DEGREES REMARK 500 DG E 21 O4' - C1' - N9 ANGL. DEV. = 4.5 DEGREES REMARK 500 DT E 22 O4' - C1' - N1 ANGL. DEV. = 1.8 DEGREES REMARK 500 DT E 24 O4' - C1' - N1 ANGL. DEV. = 2.5 DEGREES REMARK 500 DA E 25 O4' - C1' - N9 ANGL. DEV. = 2.6 DEGREES REMARK 500 DG E 29 O4' - C1' - N9 ANGL. DEV. = -4.9 DEGREES REMARK 500 DG E 31 O4' - C1' - N9 ANGL. DEV. = -5.2 DEGREES REMARK 500 DG E 32 O4' - C1' - N9 ANGL. DEV. = 3.5 DEGREES REMARK 500 DA E 35 O4' - C1' - N9 ANGL. DEV. = -5.5 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASP A 489 73.97 25.43 REMARK 500 ILE A 515 -37.51 -39.19 REMARK 500 SER A 574 49.22 38.66 REMARK 500 ASP A 580 -38.48 57.50 REMARK 500 ALA A 598 -7.86 -58.05 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 703 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS A 568 NE2 REMARK 620 2 HIS A 573 NE2 109.4 REMARK 620 3 CYS A 555 SG 109.6 109.6 REMARK 620 4 CYS A 552 SG 109.6 109.2 109.5 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 701 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS A 512 NE2 REMARK 620 2 HIS A 516 NE2 109.3 REMARK 620 3 CYS A 499 SG 109.3 109.6 REMARK 620 4 CYS A 496 SG 109.5 109.6 109.6 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 702 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS A 540 NE2 REMARK 620 2 HIS A 544 NE2 109.2 REMARK 620 3 CYS A 527 SG 109.5 109.5 REMARK 620 4 CYS A 524 SG 109.4 109.5 109.7 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 701 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 702 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 703 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GOL A 704 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GOL D 101 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 4F6M RELATED DB: PDB DBREF 4F6N A 472 604 UNP Q86T24 KAISO_HUMAN 472 604 DBREF 4F6N D 1 19 PDB 4F6N 4F6N 1 19 DBREF 4F6N E 20 38 PDB 4F6N 4F6N 20 38 SEQRES 1 A 133 ALA ASN LYS ARG MET LYS VAL LYS HIS ASP ASP HIS TYR SEQRES 2 A 133 GLU LEU ILE VAL ASP GLY ARG VAL TYR TYR ILE CYS ILE SEQRES 3 A 133 VAL CYS LYS ARG SER TYR VAL CYS LEU THR SER LEU ARG SEQRES 4 A 133 ARG HIS PHE ASN ILE HIS SER TRP GLU LYS LYS TYR PRO SEQRES 5 A 133 CYS ARG TYR CYS GLU LYS VAL PHE PRO LEU ALA GLU TYR SEQRES 6 A 133 ARG THR LYS HIS GLU ILE HIS HIS THR GLY GLU ARG ARG SEQRES 7 A 133 TYR GLN CYS LEU ALA CYS GLY LYS SER PHE ILE ASN TYR SEQRES 8 A 133 GLN PHE MET SER SER HIS ILE LYS SER VAL HIS SER GLN SEQRES 9 A 133 ASP PRO SER GLY ASP SER LYS LEU TYR ARG LEU HIS PRO SEQRES 10 A 133 CYS ARG SER LEU GLN ILE ARG GLN TYR ALA TYR LEU SER SEQRES 11 A 133 ASP ARG SER SEQRES 1 D 19 DG DT DG DT DC DA DC 5CM DG 5CM DG DT DC SEQRES 2 D 19 DT DA DT DA DC DG SEQRES 1 E 19 DC DG DT DA DT DA DG DA 5CM DG 5CM DG DG SEQRES 2 E 19 DT DG DA DC DA DC MODRES 4F6N 5CM D 8 DC MODRES 4F6N 5CM D 10 DC MODRES 4F6N 5CM E 28 DC MODRES 4F6N 5CM E 30 DC HET 5CM D 8 20 HET 5CM D 10 20 HET 5CM E 28 20 HET 5CM E 30 20 HET ZN A 701 1 HET ZN A 702 1 HET ZN A 703 1 HET GOL A 704 6 HET GOL D 101 6 HETNAM 5CM 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE HETNAM ZN ZINC ION HETNAM GOL GLYCEROL HETSYN GOL GLYCERIN; PROPANE-1,2,3-TRIOL FORMUL 2 5CM 4(C10 H16 N3 O7 P) FORMUL 4 ZN 3(ZN 2+) FORMUL 7 GOL 2(C3 H8 O3) FORMUL 9 HOH *15(H2 O) HELIX 1 1 CYS A 505 TRP A 518 1 14 HELIX 2 2 LEU A 533 GLY A 546 1 14 HELIX 3 3 ASN A 561 SER A 574 1 14 SHEET 1 A 3 HIS A 483 VAL A 488 0 SHEET 2 A 3 ARG A 491 CYS A 496 -1 O ILE A 495 N TYR A 484 SHEET 3 A 3 SER A 502 TYR A 503 -1 O TYR A 503 N TYR A 494 SHEET 1 B 2 TYR A 522 PRO A 523 0 SHEET 2 B 2 VAL A 530 PHE A 531 -1 O PHE A 531 N TYR A 522 SHEET 1 C 3 SER A 558 PHE A 559 0 SHEET 2 C 3 TYR A 550 CYS A 552 -1 N TYR A 550 O PHE A 559 SHEET 3 C 3 TYR A 584 LEU A 586 -1 O ARG A 585 N GLN A 551 LINK O3' DC D 7 P 5CM D 8 1555 1555 1.58 LINK O3' 5CM D 8 P DG D 9 1555 1555 1.58 LINK O3' DG D 9 P 5CM D 10 1555 1555 1.58 LINK O3' 5CM D 10 P DG D 11 1555 1555 1.61 LINK O3' DA E 27 P 5CM E 28 1555 1555 1.59 LINK O3' 5CM E 28 P DG E 29 1555 1555 1.58 LINK O3' DG E 29 P 5CM E 30 1555 1555 1.59 LINK O3' 5CM E 30 P DG E 31 1555 1555 1.58 LINK NE2 HIS A 568 ZN ZN A 703 1555 1555 2.04 LINK NE2 HIS A 512 ZN ZN A 701 1555 1555 2.06 LINK NE2 HIS A 540 ZN ZN A 702 1555 1555 2.07 LINK NE2 HIS A 516 ZN ZN A 701 1555 1555 2.07 LINK NE2 HIS A 544 ZN ZN A 702 1555 1555 2.07 LINK NE2 HIS A 573 ZN ZN A 703 1555 1555 2.07 LINK SG CYS A 555 ZN ZN A 703 1555 1555 2.27 LINK SG CYS A 527 ZN ZN A 702 1555 1555 2.28 LINK SG CYS A 552 ZN ZN A 703 1555 1555 2.29 LINK SG CYS A 524 ZN ZN A 702 1555 1555 2.29 LINK SG CYS A 499 ZN ZN A 701 1555 1555 2.29 LINK SG CYS A 496 ZN ZN A 701 1555 1555 2.29 SITE 1 AC1 4 CYS A 496 CYS A 499 HIS A 512 HIS A 516 SITE 1 AC2 4 CYS A 524 CYS A 527 HIS A 540 HIS A 544 SITE 1 AC3 4 CYS A 552 CYS A 555 HIS A 568 HIS A 573 SITE 1 AC4 3 TYR A 536 LYS A 539 DA D 6 SITE 1 AC5 6 DG D 3 DT D 4 DC D 5 HOH D 201 SITE 2 AC5 6 DC E 36 DA E 37 CRYST1 44.049 183.402 230.138 90.00 90.00 90.00 F 2 2 2 16 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.022702 0.000000 0.000000 0.00000 SCALE2 0.000000 0.005453 0.000000 0.00000 SCALE3 0.000000 0.000000 0.004345 0.00000 ATOM 1 N ASP A 481 -4.723 -6.476 27.874 1.00 88.62 N ANISOU 1 N ASP A 481 12358 6768 14546 -1255 -1999 -918 N ATOM 2 CA ASP A 481 -5.665 -6.113 28.980 1.00 88.71 C ANISOU 2 CA ASP A 481 12860 6702 14142 -1011 -2172 -1095 C ATOM 3 C ASP A 481 -6.568 -4.909 28.636 1.00 89.14 C ANISOU 3 C ASP A 481 13178 6587 14105 -922 -1993 -1036 C ATOM 4 O ASP A 481 -6.317 -3.779 29.087 1.00 92.14 O ANISOU 4 O ASP A 481 13759 6608 14643 -986 -2217 -1152 O ATOM 5 CB ASP A 481 -4.890 -5.859 30.284 1.00 92.16 C ANISOU 5 CB ASP A 481 13484 6855 14679 -1066 -2703 -1357 C ATOM 6 CG ASP A 481 -5.712 -6.182 31.527 1.00 92.09 C ANISOU 6 CG ASP A 481 13972 6887 14132 -808 -2842 -1550 C ATOM 7 OD1 ASP A 481 -6.216 -7.330 31.627 1.00 89.31 O ANISOU 7 OD1 ASP A 481 13616 6853 13465 -663 -2687 -1513 O ATOM 8 OD2 ASP A 481 -5.844 -5.290 32.401 1.00 94.51 O ANISOU 8 OD2 ASP A 481 14693 6888 14330 -758 -3086 -1743 O ATOM 9 N ASP A 482 -7.599 -5.167 27.820 1.00 86.08 N ANISOU 9 N ASP A 482 12781 6431 13495 -776 -1625 -859 N ATOM 10 CA ASP A 482 -8.679 -4.198 27.540 1.00 86.17 C ANISOU 10 CA ASP A 482 13043 6303 13394 -622 -1476 -807 C ATOM 11 C ASP A 482 -9.929 -4.801 26.861 1.00 82.73 C ANISOU 11 C ASP A 482 12583 6159 12690 -407 -1156 -653 C ATOM 12 O ASP A 482 -9.863 -5.822 26.163 1.00 80.05 O ANISOU 12 O ASP A 482 12000 6119 12298 -443 -987 -508 O ATOM 13 CB ASP A 482 -8.175 -2.947 26.787 1.00 88.84 C ANISOU 13 CB ASP A 482 13357 6314 14083 -831 -1483 -680 C ATOM 14 CG ASP A 482 -8.045 -1.719 27.696 1.00 92.78 C ANISOU 14 CG ASP A 482 14158 6401 14694 -829 -1773 -888 C ATOM 15 OD1 ASP A 482 -8.439 -1.800 28.882 1.00 93.63 O ANISOU 15 OD1 ASP A 482 14541 6476 14557 -645 -1938 -1133 O ATOM 16 OD2 ASP A 482 -7.554 -0.665 27.226 1.00 95.37 O ANISOU 16 OD2 ASP A 482 14482 6416 15338 -1018 -1822 -807 O ATOM 17 N HIS A 483 -11.059 -4.139 27.113 1.00 82.88 N ANISOU 17 N HIS A 483 12854 6055 12580 -179 -1097 -708 N ATOM 18 CA HIS A 483 -12.393 -4.472 26.610 1.00 80.35 C ANISOU 18 CA HIS A 483 12525 5912 12093 57 -857 -602 C ATOM 19 C HIS A 483 -13.257 -3.288 27.055 1.00 82.37 C ANISOU 19 C HIS A 483 13058 5855 12385 250 -880 -722 C ATOM 20 O HIS A 483 -12.757 -2.378 27.725 1.00 84.98 O ANISOU 20 O HIS A 483 13593 5879 12815 186 -1067 -880 O ATOM 21 CB HIS A 483 -12.912 -5.744 27.270 1.00 77.95 C ANISOU 21 CB HIS A 483 12187 5922 11510 222 -754 -704 C ATOM 22 CG HIS A 483 -13.275 -5.559 28.710 1.00 80.03 C ANISOU 22 CG HIS A 483 12761 6060 11588 385 -813 -985 C ATOM 23 ND1 HIS A 483 -12.328 -5.397 29.701 1.00 82.49 N ANISOU 23 ND1 HIS A 483 13259 6215 11867 268 -1078 -1177 N ATOM 24 CD2 HIS A 483 -14.480 -5.478 29.325 1.00 80.70 C ANISOU 24 CD2 HIS A 483 13030 6116 11515 651 -631 -1117 C ATOM 25 CE1 HIS A 483 -12.934 -5.239 30.865 1.00 84.02 C ANISOU 25 CE1 HIS A 483 13808 6297 11818 454 -1055 -1411 C ATOM 26 NE2 HIS A 483 -14.240 -5.286 30.664 1.00 83.00 N ANISOU 26 NE2 HIS A 483 13669 6247 11620 687 -743 -1382 N ATOM 27 N TYR A 484 -14.540 -3.285 26.700 1.00 81.22 N ANISOU 27 N TYR A 484 12906 5754 12198 489 -710 -662 N ATOM 28 CA TYR A 484 -15.454 -2.266 27.229 1.00 83.35 C ANISOU 28 CA TYR A 484 13403 5725 12541 717 -696 -816 C ATOM 29 C TYR A 484 -16.846 -2.823 27.527 1.00 82.27 C ANISOU 29 C TYR A 484 13216 5733 12310 1025 -459 -892 C ATOM 30 O TYR A 484 -17.287 -3.786 26.893 1.00 79.57 O ANISOU 30 O TYR A 484 12636 5682 11917 1062 -342 -738 O ATOM 31 CB TYR A 484 -15.501 -1.009 26.339 1.00 85.49 C ANISOU 31 CB TYR A 484 13732 5669 13081 666 -804 -655 C ATOM 32 CG TYR A 484 -16.150 -1.175 24.980 1.00 84.48 C ANISOU 32 CG TYR A 484 13443 5628 13026 708 -744 -362 C ATOM 33 CD1 TYR A 484 -15.411 -1.596 23.872 1.00 83.31 C ANISOU 33 CD1 TYR A 484 13169 5627 12856 459 -747 -98 C ATOM 34 CD2 TYR A 484 -17.498 -0.879 24.793 1.00 85.64 C ANISOU 34 CD2 TYR A 484 13585 5672 13283 996 -696 -358 C ATOM 35 CE1 TYR A 484 -16.009 -1.742 22.615 1.00 82.69 C ANISOU 35 CE1 TYR A 484 13039 5599 12781 494 -725 168 C ATOM 36 CE2 TYR A 484 -18.104 -1.019 23.543 1.00 85.24 C ANISOU 36 CE2 TYR A 484 13425 5660 13302 1038 -730 -91 C ATOM 37 CZ TYR A 484 -17.355 -1.453 22.463 1.00 83.75 C ANISOU 37 CZ TYR A 484 13190 5622 13009 784 -757 173 C ATOM 38 OH TYR A 484 -17.962 -1.589 21.235 1.00 84.05 O ANISOU 38 OH TYR A 484 13212 5670 13055 824 -822 432 O ATOM 39 N GLU A 485 -17.521 -2.215 28.504 1.00 84.46 N ANISOU 39 N GLU A 485 13719 5786 12587 1237 -374 -1143 N ATOM 40 CA GLU A 485 -18.818 -2.702 28.988 1.00 84.16 C ANISOU 40 CA GLU A 485 13633 5838 12506 1525 -78 -1267 C ATOM 41 C GLU A 485 -20.010 -2.041 28.294 1.00 85.39 C ANISOU 41 C GLU A 485 13641 5804 12998 1750 -15 -1189 C ATOM 42 O GLU A 485 -19.886 -0.967 27.705 1.00 87.17 O ANISOU 42 O GLU A 485 13927 5745 13450 1720 -209 -1098 O ATOM 43 CB GLU A 485 -18.919 -2.551 30.509 1.00 86.55 C ANISOU 43 CB GLU A 485 14290 6005 12591 1636 59 -1607 C ATOM 44 CG GLU A 485 -18.125 -3.600 31.284 1.00 85.25 C ANISOU 44 CG GLU A 485 14254 6083 12054 1491 31 -1684 C ATOM 45 CD GLU A 485 -17.985 -3.298 32.777 1.00 89.04 C ANISOU 45 CD GLU A 485 15226 6357 12249 1550 65 -2013 C ATOM 46 OE1 GLU A 485 -18.470 -2.244 33.252 1.00 92.36 O ANISOU 46 OE1 GLU A 485 15896 6441 12755 1702 144 -2208 O ATOM 47 OE2 GLU A 485 -17.373 -4.132 33.481 1.00 88.66 O ANISOU 47 OE2 GLU A 485 15349 6462 11874 1445 -5 -2080 O ATOM 48 N LEU A 486 -21.164 -2.697 28.379 1.00 84.65 N ANISOU 48 N LEU A 486 13348 5846 12970 1973 242 -1223 N ATOM 49 CA LEU A 486 -22.371 -2.279 27.675 1.00 85.86 C ANISOU 49 CA LEU A 486 13274 5839 13510 2203 264 -1142 C ATOM 50 C LEU A 486 -23.582 -2.790 28.455 1.00 86.81 C ANISOU 50 C LEU A 486 13262 5998 13726 2472 651 -1349 C ATOM 51 O LEU A 486 -23.705 -3.992 28.700 1.00 84.71 O ANISOU 51 O LEU A 486 12868 6049 13270 2446 842 -1343 O ATOM 52 CB LEU A 486 -22.352 -2.856 26.253 1.00 83.32 C ANISOU 52 CB LEU A 486 12689 5720 13249 2095 65 -804 C ATOM 53 CG LEU A 486 -23.250 -2.320 25.134 1.00 85.16 C ANISOU 53 CG LEU A 486 12751 5748 13858 2243 -127 -616 C ATOM 54 CD1 LEU A 486 -22.868 -2.965 23.809 1.00 82.69 C ANISOU 54 CD1 LEU A 486 12337 5653 13429 2056 -342 -290 C ATOM 55 CD2 LEU A 486 -24.726 -2.538 25.415 1.00 87.03 C ANISOU 55 CD2 LEU A 486 12714 5921 14433 2565 70 -746 C ATOM 56 N ILE A 487 -24.474 -1.886 28.845 1.00 90.22 N ANISOU 56 N ILE A 487 13715 6086 14478 2726 791 -1534 N ATOM 57 CA ILE A 487 -25.582 -2.245 29.727 1.00 92.13 C ANISOU 57 CA ILE A 487 13858 6303 14844 2976 1252 -1778 C ATOM 58 C ILE A 487 -26.956 -1.975 29.099 1.00 94.49 C ANISOU 58 C ILE A 487 13739 6412 15749 3253 1298 -1741 C ATOM 59 O ILE A 487 -27.313 -0.819 28.843 1.00 97.65 O ANISOU 59 O ILE A 487 14149 6438 16514 3401 1149 -1780 O ATOM 60 CB ILE A 487 -25.462 -1.520 31.097 1.00 95.55 C ANISOU 60 CB ILE A 487 14729 6471 15104 3060 1511 -2133 C ATOM 61 CG1 ILE A 487 -24.122 -1.851 31.764 1.00 93.50 C ANISOU 61 CG1 ILE A 487 14884 6373 14270 2792 1391 -2178 C ATOM 62 CG2 ILE A 487 -26.635 -1.880 32.015 1.00 98.40 C ANISOU 62 CG2 ILE A 487 15020 6779 15589 3313 2089 -2394 C ATOM 63 CD1 ILE A 487 -23.821 -1.047 33.019 1.00 97.00 C ANISOU 63 CD1 ILE A 487 15856 6516 14485 2834 1509 -2512 C ATOM 64 N VAL A 488 -27.718 -3.047 28.863 1.00 93.25 N ANISOU 64 N VAL A 488 13208 6488 15735 3321 1475 -1671 N ATOM 65 CA VAL A 488 -29.092 -2.948 28.343 1.00 95.88 C ANISOU 65 CA VAL A 488 13076 6640 16714 3588 1514 -1657 C ATOM 66 C VAL A 488 -30.113 -3.497 29.347 1.00 98.45 C ANISOU 66 C VAL A 488 13208 6961 17237 3785 2124 -1921 C ATOM 67 O VAL A 488 -30.103 -4.688 29.657 1.00 96.37 O ANISOU 67 O VAL A 488 12874 7020 16723 3685 2370 -1901 O ATOM 68 CB VAL A 488 -29.267 -3.688 26.991 1.00 93.14 C ANISOU 68 CB VAL A 488 12386 6500 16503 3510 1134 -1325 C ATOM 69 CG1 VAL A 488 -30.666 -3.447 26.432 1.00 96.76 C ANISOU 69 CG1 VAL A 488 12374 6694 17696 3795 1055 -1317 C ATOM 70 CG2 VAL A 488 -28.215 -3.246 25.986 1.00 90.64 C ANISOU 70 CG2 VAL A 488 12311 6199 15928 3284 619 -1053 C ATOM 71 N ASP A 489 -31.002 -2.623 29.818 1.00103.42 N ANISOU 71 N ASP A 489 13748 7204 18344 4062 2382 -2163 N ATOM 72 CA ASP A 489 -31.958 -2.924 30.895 1.00107.09 C ANISOU 72 CA ASP A 489 14089 7578 19022 4258 3074 -2466 C ATOM 73 C ASP A 489 -31.497 -4.037 31.841 1.00104.95 C ANISOU 73 C ASP A 489 14104 7647 18125 4078 3493 -2540 C ATOM 74 O ASP A 489 -32.001 -5.164 31.788 1.00103.79 O ANISOU 74 O ASP A 489 13642 7734 18059 4054 3719 -2468 O ATOM 75 CB ASP A 489 -33.363 -3.214 30.340 1.00109.76 C ANISOU 75 CB ASP A 489 13738 7792 20172 4493 3164 -2440 C ATOM 76 CG ASP A 489 -34.479 -2.853 31.337 1.00115.90 C ANISOU 76 CG ASP A 489 14348 8245 21442 4781 3857 -2806 C ATOM 77 OD1 ASP A 489 -34.662 -3.575 32.344 1.00116.59 O ANISOU 77 OD1 ASP A 489 14553 8467 21279 4751 4497 -2984 O ATOM 78 OD2 ASP A 489 -35.181 -1.843 31.108 1.00120.30 O ANISOU 78 OD2 ASP A 489 14667 8388 22652 5041 3780 -2917 O ATOM 79 N GLY A 490 -30.532 -3.709 32.698 1.00104.69 N ANISOU 79 N GLY A 490 14684 7612 17482 3947 3553 -2680 N ATOM 80 CA GLY A 490 -30.016 -4.652 33.682 1.00103.43 C ANISOU 80 CA GLY A 490 14909 7711 16680 3780 3885 -2762 C ATOM 81 C GLY A 490 -28.822 -5.445 33.178 1.00 97.95 C ANISOU 81 C GLY A 490 14331 7400 15485 3474 3424 -2488 C ATOM 82 O GLY A 490 -27.724 -5.324 33.726 1.00 96.98 O ANISOU 82 O GLY A 490 14714 7322 14813 3300 3267 -2537 O ATOM 83 N ARG A 491 -29.032 -6.253 32.136 1.00 94.67 N ANISOU 83 N ARG A 491 13447 7237 15288 3414 3194 -2215 N ATOM 84 CA ARG A 491 -27.975 -7.109 31.579 1.00 89.67 C ANISOU 84 CA ARG A 491 12864 6968 14238 3138 2810 -1960 C ATOM 85 C ARG A 491 -26.690 -6.342 31.242 1.00 87.59 C ANISOU 85 C ARG A 491 12919 6661 13701 2960 2319 -1875 C ATOM 86 O ARG A 491 -26.720 -5.343 30.520 1.00 88.50 O ANISOU 86 O ARG A 491 12950 6555 14123 3016 2022 -1805 O ATOM 87 CB ARG A 491 -28.472 -7.865 30.335 1.00 87.56 C ANISOU 87 CB ARG A 491 12054 6898 14315 3129 2584 -1690 C ATOM 88 CG ARG A 491 -29.419 -9.055 30.604 1.00 89.07 C ANISOU 88 CG ARG A 491 11918 7249 14673 3194 2996 -1709 C ATOM 89 CD ARG A 491 -30.341 -9.320 29.401 1.00 90.42 C ANISOU 89 CD ARG A 491 11496 7416 15445 3298 2768 -1526 C ATOM 90 NE ARG A 491 -30.921 -8.075 28.874 1.00 94.47 N ANISOU 90 NE ARG A 491 11839 7566 16491 3500 2557 -1555 N ATOM 91 CZ ARG A 491 -32.001 -7.471 29.369 1.00100.16 C ANISOU 91 CZ ARG A 491 12353 7963 17742 3761 2908 -1776 C ATOM 92 NH1 ARG A 491 -32.647 -7.995 30.407 1.00103.05 N ANISOU 92 NH1 ARG A 491 12664 8326 18165 3841 3551 -1989 N ATOM 93 NH2 ARG A 491 -32.444 -6.340 28.823 1.00103.23 N ANISOU 93 NH2 ARG A 491 12594 8006 18622 3944 2637 -1785 N ATOM 94 N VAL A 492 -25.571 -6.818 31.783 1.00 85.09 N ANISOU 94 N VAL A 492 12964 6529 12839 2743 2231 -1882 N ATOM 95 CA VAL A 492 -24.242 -6.291 31.463 1.00 82.88 C ANISOU 95 CA VAL A 492 12922 6237 12332 2530 1772 -1789 C ATOM 96 C VAL A 492 -23.609 -7.156 30.380 1.00 78.22 C ANISOU 96 C VAL A 492 12066 5973 11681 2327 1462 -1487 C ATOM 97 O VAL A 492 -23.668 -8.380 30.451 1.00 76.03 O ANISOU 97 O VAL A 492 11666 5982 11238 2271 1588 -1422 O ATOM 98 CB VAL A 492 -23.322 -6.275 32.713 1.00 83.79 C ANISOU 98 CB VAL A 492 13584 6314 11940 2411 1795 -1992 C ATOM 99 CG1 VAL A 492 -21.905 -5.860 32.344 1.00 81.97 C ANISOU 99 CG1 VAL A 492 13505 6079 11563 2165 1302 -1887 C ATOM 100 CG2 VAL A 492 -23.890 -5.353 33.783 1.00 88.44 C ANISOU 100 CG2 VAL A 492 14527 6547 12530 2606 2108 -2313 C ATOM 101 N TYR A 493 -23.023 -6.517 29.373 1.00 76.99 N ANISOU 101 N TYR A 493 11845 5750 11658 2215 1085 -1306 N ATOM 102 CA TYR A 493 -22.280 -7.226 28.330 1.00 73.19 C ANISOU 102 CA TYR A 493 11184 5540 11085 2002 820 -1037 C ATOM 103 C TYR A 493 -20.853 -6.709 28.265 1.00 72.58 C ANISOU 103 C TYR A 493 11339 5407 10831 1759 533 -999 C ATOM 104 O TYR A 493 -20.593 -5.545 28.549 1.00 74.94 O ANISOU 104 O TYR A 493 11860 5406 11208 1765 431 -1101 O ATOM 105 CB TYR A 493 -22.950 -7.066 26.965 1.00 72.77 C ANISOU 105 CB TYR A 493 10822 5456 11371 2070 658 -809 C ATOM 106 CG TYR A 493 -24.341 -7.642 26.894 1.00 73.44 C ANISOU 106 CG TYR A 493 10590 5584 11730 2293 872 -827 C ATOM 107 CD1 TYR A 493 -25.451 -6.872 27.237 1.00 76.93 C ANISOU 107 CD1 TYR A 493 10951 5728 12552 2554 1035 -981 C ATOM 108 CD2 TYR A 493 -24.553 -8.954 26.478 1.00 70.68 C ANISOU 108 CD2 TYR A 493 9995 5546 11316 2244 912 -702 C ATOM 109 CE1 TYR A 493 -26.735 -7.395 27.175 1.00 77.96 C ANISOU 109 CE1 TYR A 493 10722 5866 13034 2754 1240 -1009 C ATOM 110 CE2 TYR A 493 -25.836 -9.488 26.413 1.00 71.59 C ANISOU 110 CE2 TYR A 493 9781 5673 11748 2434 1093 -722 C ATOM 111 CZ TYR A 493 -26.919 -8.701 26.765 1.00 75.46 C ANISOU 111 CZ TYR A 493 10157 5859 12656 2685 1259 -875 C ATOM 112 OH TYR A 493 -28.190 -9.216 26.706 1.00 77.34 O ANISOU 112 OH TYR A 493 10007 6077 13302 2868 1447 -906 O ATOM 113 N TYR A 494 -19.931 -7.586 27.896 1.00 69.76 N ANISOU 113 N TYR A 494 10907 5319 10279 1544 410 -863 N ATOM 114 CA TYR A 494 -18.535 -7.214 27.751 1.00 69.62 C ANISOU 114 CA TYR A 494 11017 5254 10182 1294 155 -817 C ATOM 115 C TYR A 494 -18.152 -7.306 26.277 1.00 68.28 C ANISOU 115 C TYR A 494 10633 5177 10133 1141 12 -532 C ATOM 116 O TYR A 494 -18.331 -8.356 25.651 1.00 65.97 O ANISOU 116 O TYR A 494 10127 5158 9781 1121 68 -393 O ATOM 117 CB TYR A 494 -17.649 -8.104 28.630 1.00 68.23 C ANISOU 117 CB TYR A 494 10953 5256 9716 1163 127 -924 C ATOM 118 CG TYR A 494 -18.132 -8.165 30.056 1.00 69.86 C ANISOU 118 CG TYR A 494 11453 5379 9713 1315 304 -1187 C ATOM 119 CD1 TYR A 494 -19.078 -9.116 30.453 1.00 69.21 C ANISOU 119 CD1 TYR A 494 11307 5475 9515 1467 604 -1226 C ATOM 120 CD2 TYR A 494 -17.667 -7.258 31.012 1.00 72.65 C ANISOU 120 CD2 TYR A 494 12184 5446 9976 1301 189 -1401 C ATOM 121 CE1 TYR A 494 -19.546 -9.170 31.768 1.00 71.29 C ANISOU 121 CE1 TYR A 494 11900 5636 9550 1596 842 -1464 C ATOM 122 CE2 TYR A 494 -18.129 -7.299 32.332 1.00 74.86 C ANISOU 122 CE2 TYR A 494 12829 5620 9997 1441 383 -1654 C ATOM 123 CZ TYR A 494 -19.067 -8.260 32.700 1.00 74.45 C ANISOU 123 CZ TYR A 494 12729 5752 9806 1585 737 -1679 C ATOM 124 OH TYR A 494 -19.529 -8.313 33.995 1.00 77.21 O ANISOU 124 OH TYR A 494 13490 5980 9868 1708 999 -1922 O ATOM 125 N ILE A 495 -17.653 -6.198 25.728 1.00 70.17 N ANISOU 125 N ILE A 495 10969 5166 10526 1031 -156 -448 N ATOM 126 CA ILE A 495 -17.300 -6.124 24.314 1.00 69.91 C ANISOU 126 CA ILE A 495 10833 5156 10573 875 -253 -172 C ATOM 127 C ILE A 495 -15.785 -6.102 24.125 1.00 69.97 C ANISOU 127 C ILE A 495 10857 5176 10554 567 -341 -116 C ATOM 128 O ILE A 495 -15.068 -5.379 24.829 1.00 71.79 O ANISOU 128 O ILE A 495 11230 5198 10847 472 -447 -253 O ATOM 129 CB ILE A 495 -17.933 -4.892 23.625 1.00 72.54 C ANISOU 129 CB ILE A 495 11271 5160 11130 967 -361 -63 C ATOM 130 CG1 ILE A 495 -19.367 -4.643 24.123 1.00 73.99 C ANISOU 130 CG1 ILE A 495 11423 5225 11465 1295 -284 -200 C ATOM 131 CG2 ILE A 495 -17.882 -5.032 22.100 1.00 72.30 C ANISOU 131 CG2 ILE A 495 11196 5173 11100 851 -439 244 C ATOM 132 CD1 ILE A 495 -20.381 -5.718 23.747 1.00 72.24 C ANISOU 132 CD1 ILE A 495 10949 5249 11249 1453 -183 -135 C ATOM 133 N CYS A 496 -15.317 -6.904 23.170 1.00 68.41 N ANISOU 133 N CYS A 496 10502 5201 10291 413 -293 71 N ATOM 134 CA CYS A 496 -13.898 -7.031 22.856 1.00 69.01 C ANISOU 134 CA CYS A 496 10511 5303 10408 118 -308 132 C ATOM 135 C CYS A 496 -13.384 -5.781 22.128 1.00 71.72 C ANISOU 135 C CYS A 496 10991 5327 10932 -59 -364 274 C ATOM 136 O CYS A 496 -13.953 -5.394 21.105 1.00 72.40 O ANISOU 136 O CYS A 496 11175 5322 11012 -30 -346 474 O ATOM 137 CB CYS A 496 -13.693 -8.279 21.999 1.00 66.53 C ANISOU 137 CB CYS A 496 10006 5304 9970 37 -177 278 C ATOM 138 SG CYS A 496 -12.101 -8.388 21.188 1.00 69.68 S ANISOU 138 SG CYS A 496 10287 5700 10487 -321 -89 403 S ATOM 139 N ILE A 497 -12.319 -5.149 22.640 1.00 73.74 N ANISOU 139 N ILE A 497 11273 5386 11360 -248 -456 178 N ATOM 140 CA ILE A 497 -11.805 -3.909 22.015 1.00 76.78 C ANISOU 140 CA ILE A 497 11792 5428 11952 -438 -493 310 C ATOM 141 C ILE A 497 -11.372 -4.078 20.563 1.00 77.02 C ANISOU 141 C ILE A 497 11795 5497 11972 -651 -309 595 C ATOM 142 O ILE A 497 -11.396 -3.109 19.803 1.00 79.65 O ANISOU 142 O ILE A 497 12326 5555 12380 -746 -304 773 O ATOM 143 CB ILE A 497 -10.633 -3.196 22.783 1.00 79.28 C ANISOU 143 CB ILE A 497 12105 5490 12526 -644 -642 157 C ATOM 144 CG1 ILE A 497 -9.591 -4.186 23.316 1.00 78.40 C ANISOU 144 CG1 ILE A 497 11737 5585 12468 -783 -664 32 C ATOM 145 CG2 ILE A 497 -11.164 -2.229 23.859 1.00 81.22 C ANISOU 145 CG2 ILE A 497 12590 5462 12808 -466 -845 -60 C ATOM 146 CD1 ILE A 497 -8.172 -3.598 23.374 1.00 81.47 C ANISOU 146 CD1 ILE A 497 12004 5720 13232 -1100 -756 6 C ATOM 147 N VAL A 498 -10.977 -5.292 20.184 1.00 74.76 N ANISOU 147 N VAL A 498 11303 5525 11577 -725 -148 637 N ATOM 148 CA VAL A 498 -10.467 -5.546 18.836 1.00 75.33 C ANISOU 148 CA VAL A 498 11381 5635 11605 -941 88 878 C ATOM 149 C VAL A 498 -11.589 -5.815 17.830 1.00 74.60 C ANISOU 149 C VAL A 498 11485 5630 11230 -787 119 1073 C ATOM 150 O VAL A 498 -11.764 -5.058 16.887 1.00 76.90 O ANISOU 150 O VAL A 498 12048 5692 11477 -864 138 1287 O ATOM 151 CB VAL A 498 -9.389 -6.673 18.810 1.00 74.17 C ANISOU 151 CB VAL A 498 10922 5735 11526 -1115 269 821 C ATOM 152 CG1 VAL A 498 -9.032 -7.060 17.379 1.00 74.91 C ANISOU 152 CG1 VAL A 498 11067 5887 11507 -1300 585 1052 C ATOM 153 CG2 VAL A 498 -8.136 -6.243 19.560 1.00 75.92 C ANISOU 153 CG2 VAL A 498 10948 5777 12119 -1324 199 671 C ATOM 154 N CYS A 499 -12.348 -6.887 18.033 1.00 71.89 N ANISOU 154 N CYS A 499 11022 5587 10705 -574 94 1005 N ATOM 155 CA CYS A 499 -13.306 -7.337 17.024 1.00 71.53 C ANISOU 155 CA CYS A 499 11118 5638 10423 -452 91 1180 C ATOM 156 C CYS A 499 -14.766 -7.070 17.407 1.00 70.93 C ANISOU 156 C CYS A 499 11095 5505 10351 -130 -138 1131 C ATOM 157 O CYS A 499 -15.679 -7.305 16.612 1.00 71.01 O ANISOU 157 O CYS A 499 11215 5531 10237 -5 -231 1269 O ATOM 158 CB CYS A 499 -13.100 -8.825 16.745 1.00 69.11 C ANISOU 158 CB CYS A 499 10620 5691 9947 -472 246 1164 C ATOM 159 SG CYS A 499 -13.631 -9.863 18.099 1.00 67.48 S ANISOU 159 SG CYS A 499 10117 5776 9748 -233 160 905 S ATOM 160 N LYS A 500 -14.972 -6.617 18.641 1.00 70.65 N ANISOU 160 N LYS A 500 10978 5388 10477 3 -227 917 N ATOM 161 CA LYS A 500 -16.276 -6.147 19.129 1.00 70.92 C ANISOU 161 CA LYS A 500 11047 5293 10606 302 -381 833 C ATOM 162 C LYS A 500 -17.385 -7.201 19.279 1.00 68.54 C ANISOU 162 C LYS A 500 10564 5242 10237 543 -376 775 C ATOM 163 O LYS A 500 -18.567 -6.864 19.250 1.00 69.55 O ANISOU 163 O LYS A 500 10695 5239 10493 778 -495 773 O ATOM 164 CB LYS A 500 -16.761 -4.917 18.325 1.00 74.16 C ANISOU 164 CB LYS A 500 11724 5335 11117 331 -549 1015 C ATOM 165 CG LYS A 500 -15.838 -3.695 18.434 1.00 76.96 C ANISOU 165 CG LYS A 500 12259 5374 11610 128 -563 1033 C ATOM 166 CD LYS A 500 -16.471 -2.420 17.890 1.00 80.46 C ANISOU 166 CD LYS A 500 12975 5411 12184 209 -765 1177 C ATOM 167 CE LYS A 500 -15.514 -1.242 18.016 1.00 83.05 C ANISOU 167 CE LYS A 500 13477 5413 12665 -16 -768 1196 C ATOM 168 NZ LYS A 500 -16.086 -0.008 17.409 1.00 86.68 N ANISOU 168 NZ LYS A 500 14239 5450 13244 48 -977 1365 N ATOM 169 N ARG A 501 -17.011 -8.465 19.456 1.00 65.73 N ANISOU 169 N ARG A 501 10024 5217 9732 486 -244 723 N ATOM 170 CA ARG A 501 -17.981 -9.499 19.833 1.00 63.76 C ANISOU 170 CA ARG A 501 9581 5197 9449 695 -211 635 C ATOM 171 C ARG A 501 -18.457 -9.251 21.263 1.00 64.11 C ANISOU 171 C ARG A 501 9574 5185 9601 875 -158 387 C ATOM 172 O ARG A 501 -17.721 -8.670 22.067 1.00 65.04 O ANISOU 172 O ARG A 501 9792 5189 9733 794 -147 255 O ATOM 173 CB ARG A 501 -17.357 -10.881 19.755 1.00 61.07 C ANISOU 173 CB ARG A 501 9084 5193 8926 575 -84 630 C ATOM 174 CG ARG A 501 -17.099 -11.382 18.360 1.00 60.94 C ANISOU 174 CG ARG A 501 9126 5266 8764 440 -79 843 C ATOM 175 CD ARG A 501 -16.229 -12.620 18.403 1.00 59.22 C ANISOU 175 CD ARG A 501 8749 5338 8413 301 76 801 C ATOM 176 NE ARG A 501 -16.054 -13.181 17.073 1.00 60.16 N ANISOU 176 NE ARG A 501 8954 5541 8363 189 123 978 N ATOM 177 CZ ARG A 501 -16.777 -14.185 16.583 1.00 59.88 C ANISOU 177 CZ ARG A 501 8863 5678 8210 289 82 1019 C ATOM 178 NH1 ARG A 501 -17.732 -14.764 17.312 1.00 58.28 N ANISOU 178 NH1 ARG A 501 8470 5589 8084 494 19 907 N ATOM 179 NH2 ARG A 501 -16.538 -14.616 15.356 1.00 60.61 N ANISOU 179 NH2 ARG A 501 9110 5809 8108 173 122 1167 N ATOM 180 N SER A 502 -19.677 -9.683 21.582 1.00 63.77 N ANISOU 180 N SER A 502 9392 5198 9642 1111 -116 315 N ATOM 181 CA SER A 502 -20.235 -9.470 22.924 1.00 64.45 C ANISOU 181 CA SER A 502 9467 5209 9811 1292 19 73 C ATOM 182 C SER A 502 -20.167 -10.740 23.766 1.00 62.21 C ANISOU 182 C SER A 502 9074 5214 9349 1296 203 -52 C ATOM 183 O SER A 502 -20.207 -11.851 23.237 1.00 60.12 O ANISOU 183 O SER A 502 8649 5196 8995 1251 218 49 O ATOM 184 CB SER A 502 -21.677 -8.970 22.845 1.00 66.49 C ANISOU 184 CB SER A 502 9631 5269 10364 1561 6 48 C ATOM 185 OG SER A 502 -22.575 -10.062 22.770 1.00 65.61 O ANISOU 185 OG SER A 502 9265 5353 10308 1682 100 53 O ATOM 186 N TYR A 503 -20.067 -10.570 25.079 1.00 62.94 N ANISOU 186 N TYR A 503 9298 5248 9370 1348 330 -271 N ATOM 187 CA TYR A 503 -19.935 -11.700 25.992 1.00 61.51 C ANISOU 187 CA TYR A 503 9108 5291 8974 1340 488 -386 C ATOM 188 C TYR A 503 -20.693 -11.428 27.281 1.00 63.75 C ANISOU 188 C TYR A 503 9539 5436 9246 1525 719 -617 C ATOM 189 O TYR A 503 -20.603 -10.332 27.838 1.00 66.12 O ANISOU 189 O TYR A 503 10063 5475 9584 1570 704 -752 O ATOM 190 CB TYR A 503 -18.455 -11.990 26.285 1.00 60.24 C ANISOU 190 CB TYR A 503 9061 5220 8607 1112 358 -404 C ATOM 191 CG TYR A 503 -17.668 -12.444 25.069 1.00 58.28 C ANISOU 191 CG TYR A 503 8650 5126 8369 922 233 -199 C ATOM 192 CD1 TYR A 503 -16.975 -11.527 24.270 1.00 58.91 C ANISOU 192 CD1 TYR A 503 8778 5045 8560 777 99 -88 C ATOM 193 CD2 TYR A 503 -17.622 -13.796 24.710 1.00 55.83 C ANISOU 193 CD2 TYR A 503 8158 5099 7954 883 285 -122 C ATOM 194 CE1 TYR A 503 -16.259 -11.947 23.142 1.00 57.24 C ANISOU 194 CE1 TYR A 503 8456 4954 8338 595 67 92 C ATOM 195 CE2 TYR A 503 -16.908 -14.227 23.590 1.00 53.84 C ANISOU 195 CE2 TYR A 503 7787 4971 7699 717 222 42 C ATOM 196 CZ TYR A 503 -16.229 -13.299 22.815 1.00 55.17 C ANISOU 196 CZ TYR A 503 8023 4978 7960 572 137 145 C ATOM 197 OH TYR A 503 -15.538 -13.739 21.713 1.00 54.11 O ANISOU 197 OH TYR A 503 7808 4949 7801 403 152 296 O ATOM 198 N VAL A 504 -21.439 -12.429 27.744 1.00 63.36 N ANISOU 198 N VAL A 504 9384 5543 9146 1624 957 -665 N ATOM 199 CA VAL A 504 -22.211 -12.330 28.990 1.00 65.94 C ANISOU 199 CA VAL A 504 9874 5748 9434 1788 1282 -884 C ATOM 200 C VAL A 504 -21.291 -12.488 30.201 1.00 66.47 C ANISOU 200 C VAL A 504 10339 5809 9107 1683 1283 -1040 C ATOM 201 O VAL A 504 -21.648 -12.108 31.307 1.00 69.25 O ANISOU 201 O VAL A 504 10989 5987 9335 1786 1508 -1247 O ATOM 202 CB VAL A 504 -23.360 -13.396 29.049 1.00 65.82 C ANISOU 202 CB VAL A 504 9596 5879 9533 1908 1580 -867 C ATOM 203 CG1 VAL A 504 -24.300 -13.154 30.233 1.00 69.15 C ANISOU 203 CG1 VAL A 504 10162 6121 9990 2088 2012 -1094 C ATOM 204 CG2 VAL A 504 -24.162 -13.414 27.744 1.00 65.51 C ANISOU 204 CG2 VAL A 504 9149 5854 9887 1987 1457 -693 C ATOM 205 N CYS A 505 -20.101 -13.040 29.978 1.00 64.43 N ANISOU 205 N CYS A 505 10101 5714 8665 1480 1019 -948 N ATOM 206 CA CYS A 505 -19.182 -13.383 31.060 1.00 65.13 C ANISOU 206 CA CYS A 505 10537 5802 8409 1373 923 -1073 C ATOM 207 C CYS A 505 -17.761 -12.922 30.753 1.00 64.45 C ANISOU 207 C CYS A 505 10492 5662 8336 1173 530 -1036 C ATOM 208 O CYS A 505 -17.189 -13.297 29.724 1.00 62.21 O ANISOU 208 O CYS A 505 9917 5534 8185 1044 377 -860 O ATOM 209 CB CYS A 505 -19.190 -14.898 31.287 1.00 63.42 C ANISOU 209 CB CYS A 505 10255 5846 7994 1332 1011 -1011 C ATOM 210 SG CYS A 505 -20.840 -15.617 31.546 1.00 65.48 S ANISOU 210 SG CYS A 505 10382 6180 8317 1526 1504 -1025 S ATOM 211 N LEU A 506 -17.184 -12.130 31.654 1.00 66.81 N ANISOU 211 N LEU A 506 11157 5721 8508 1140 381 -1212 N ATOM 212 CA LEU A 506 -15.831 -11.624 31.460 1.00 66.93 C ANISOU 212 CA LEU A 506 11189 5633 8610 941 1 -1200 C ATOM 213 C LEU A 506 -14.851 -12.765 31.198 1.00 64.84 C ANISOU 213 C LEU A 506 10731 5594 8312 774 -194 -1095 C ATOM 214 O LEU A 506 -13.986 -12.655 30.330 1.00 63.83 O ANISOU 214 O LEU A 506 10340 5497 8415 611 -371 -975 O ATOM 215 CB LEU A 506 -15.389 -10.775 32.648 1.00 70.32 C ANISOU 215 CB LEU A 506 12086 5756 8877 935 -173 -1436 C ATOM 216 CG LEU A 506 -14.118 -9.944 32.451 1.00 71.60 C ANISOU 216 CG LEU A 506 12245 5720 9240 738 -570 -1448 C ATOM 217 CD1 LEU A 506 -14.109 -9.222 31.107 1.00 70.55 C ANISOU 217 CD1 LEU A 506 11766 5565 9476 675 -546 -1264 C ATOM 218 CD2 LEU A 506 -13.956 -8.952 33.594 1.00 75.62 C ANISOU 218 CD2 LEU A 506 13252 5878 9603 772 -725 -1701 C ATOM 219 N THR A 507 -15.013 -13.857 31.944 1.00 64.54 N ANISOU 219 N THR A 507 10831 5692 8001 816 -131 -1140 N ATOM 220 CA THR A 507 -14.303 -15.113 31.707 1.00 62.57 C ANISOU 220 CA THR A 507 10379 5666 7727 703 -273 -1039 C ATOM 221 C THR A 507 -14.208 -15.473 30.225 1.00 59.83 C ANISOU 221 C THR A 507 9550 5528 7656 632 -213 -829 C ATOM 222 O THR A 507 -13.123 -15.778 29.716 1.00 59.25 O ANISOU 222 O THR A 507 9262 5508 7743 471 -416 -764 O ATOM 223 CB THR A 507 -15.023 -16.259 32.424 1.00 62.17 C ANISOU 223 CB THR A 507 10491 5758 7373 809 -65 -1059 C ATOM 224 OG1 THR A 507 -14.620 -16.285 33.791 1.00 65.53 O ANISOU 224 OG1 THR A 507 11416 6008 7475 802 -239 -1229 O ATOM 225 CG2 THR A 507 -14.690 -17.604 31.798 1.00 59.90 C ANISOU 225 CG2 THR A 507 9878 5741 7139 736 -106 -907 C ATOM 226 N SER A 508 -15.349 -15.443 29.539 1.00 58.56 N ANISOU 226 N SER A 508 9231 5457 7561 755 66 -734 N ATOM 227 CA SER A 508 -15.399 -15.857 28.153 1.00 56.12 C ANISOU 227 CA SER A 508 8559 5331 7435 704 118 -539 C ATOM 228 C SER A 508 -14.663 -14.876 27.258 1.00 56.75 C ANISOU 228 C SER A 508 8538 5281 7742 567 -12 -459 C ATOM 229 O SER A 508 -14.058 -15.277 26.262 1.00 55.69 O ANISOU 229 O SER A 508 8174 5265 7720 437 -36 -326 O ATOM 230 CB SER A 508 -16.839 -16.033 27.695 1.00 55.29 C ANISOU 230 CB SER A 508 8335 5304 7369 875 373 -467 C ATOM 231 OG SER A 508 -17.417 -17.144 28.348 1.00 54.46 O ANISOU 231 OG SER A 508 8253 5343 7096 958 530 -506 O ATOM 232 N LEU A 509 -14.707 -13.596 27.618 1.00 58.76 N ANISOU 232 N LEU A 509 8990 5274 8062 589 -69 -545 N ATOM 233 CA LEU A 509 -13.977 -12.587 26.869 1.00 59.73 C ANISOU 233 CA LEU A 509 9059 5228 8408 439 -188 -469 C ATOM 234 C LEU A 509 -12.474 -12.819 26.971 1.00 60.19 C ANISOU 234 C LEU A 509 9026 5271 8573 217 -395 -495 C ATOM 235 O LEU A 509 -11.791 -12.902 25.953 1.00 59.76 O ANISOU 235 O LEU A 509 8746 5264 8696 56 -373 -359 O ATOM 236 CB LEU A 509 -14.338 -11.176 27.331 1.00 62.22 C ANISOU 236 CB LEU A 509 9620 5234 8787 514 -227 -574 C ATOM 237 CG LEU A 509 -13.743 -10.070 26.463 1.00 62.82 C ANISOU 237 CG LEU A 509 9657 5105 9107 361 -322 -464 C ATOM 238 CD1 LEU A 509 -14.751 -8.960 26.267 1.00 64.41 C ANISOU 238 CD1 LEU A 509 9994 5087 9390 517 -259 -453 C ATOM 239 CD2 LEU A 509 -12.458 -9.560 27.074 1.00 64.11 C ANISOU 239 CD2 LEU A 509 9904 5075 9381 175 -562 -582 C ATOM 240 N ARG A 510 -11.972 -12.921 28.197 1.00 61.58 N ANISOU 240 N ARG A 510 9388 5354 8654 210 -594 -675 N ATOM 241 CA ARG A 510 -10.563 -13.213 28.436 1.00 62.60 C ANISOU 241 CA ARG A 510 9403 5435 8946 19 -864 -726 C ATOM 242 C ARG A 510 -10.129 -14.417 27.597 1.00 60.28 C ANISOU 242 C ARG A 510 8758 5405 8741 -61 -772 -594 C ATOM 243 O ARG A 510 -9.123 -14.353 26.884 1.00 60.69 O ANISOU 243 O ARG A 510 8545 5424 9089 -247 -803 -530 O ATOM 244 CB ARG A 510 -10.313 -13.481 29.923 1.00 64.35 C ANISOU 244 CB ARG A 510 9937 5554 8960 68 -1127 -928 C ATOM 245 CG ARG A 510 -10.775 -12.369 30.878 1.00 68.06 C ANISOU 245 CG ARG A 510 10839 5748 9275 164 -1197 -1099 C ATOM 246 CD ARG A 510 -9.659 -11.396 31.248 1.00 72.24 C ANISOU 246 CD ARG A 510 11448 5958 10041 -1 -1566 -1214 C ATOM 247 NE ARG A 510 -9.697 -10.133 30.503 1.00 73.76 N ANISOU 247 NE ARG A 510 11561 5972 10495 -65 -1483 -1151 N ATOM 248 CZ ARG A 510 -9.968 -8.944 31.049 1.00 77.12 C ANISOU 248 CZ ARG A 510 12305 6104 10892 -14 -1561 -1284 C ATOM 249 NH1 ARG A 510 -10.241 -8.843 32.348 1.00 79.26 N ANISOU 249 NH1 ARG A 510 13027 6232 10857 104 -1695 -1502 N ATOM 250 NH2 ARG A 510 -9.969 -7.845 30.300 1.00 77.79 N ANISOU 250 NH2 ARG A 510 12304 6015 11237 -83 -1498 -1201 N ATOM 251 N ARG A 511 -10.915 -15.493 27.655 1.00 58.07 N ANISOU 251 N ARG A 511 8473 5364 8226 77 -622 -558 N ATOM 252 CA ARG A 511 -10.598 -16.721 26.934 1.00 56.05 C ANISOU 252 CA ARG A 511 7923 5351 8022 26 -538 -455 C ATOM 253 C ARG A 511 -10.496 -16.458 25.438 1.00 55.74 C ANISOU 253 C ARG A 511 7655 5364 8159 -73 -333 -285 C ATOM 254 O ARG A 511 -9.551 -16.909 24.786 1.00 56.06 O ANISOU 254 O ARG A 511 7443 5456 8401 -222 -309 -239 O ATOM 255 CB ARG A 511 -11.624 -17.812 27.228 1.00 53.90 C ANISOU 255 CB ARG A 511 7712 5295 7471 194 -399 -438 C ATOM 256 CG ARG A 511 -11.402 -19.119 26.455 1.00 51.00 C ANISOU 256 CG ARG A 511 7064 5171 7145 158 -312 -338 C ATOM 257 CD ARG A 511 -12.376 -20.218 26.874 1.00 48.00 C ANISOU 257 CD ARG A 511 6753 4968 6517 307 -204 -330 C ATOM 258 NE ARG A 511 -13.774 -19.809 26.751 1.00 47.26 N ANISOU 258 NE ARG A 511 6761 4885 6309 454 12 -290 N ATOM 259 CZ ARG A 511 -14.813 -20.537 27.150 1.00 46.62 C ANISOU 259 CZ ARG A 511 6736 4910 6067 586 162 -289 C ATOM 260 NH1 ARG A 511 -14.631 -21.737 27.693 1.00 46.95 N ANISOU 260 NH1 ARG A 511 6792 5063 5983 586 122 -309 N ATOM 261 NH2 ARG A 511 -16.041 -20.064 27.005 1.00 46.75 N ANISOU 261 NH2 ARG A 511 6780 4895 6088 717 352 -267 N ATOM 262 N HIS A 512 -11.460 -15.714 24.908 1.00 55.80 N ANISOU 262 N HIS A 512 7777 5329 8096 10 -184 -199 N ATOM 263 CA HIS A 512 -11.457 -15.333 23.509 1.00 55.96 C ANISOU 263 CA HIS A 512 7703 5346 8214 -81 -22 -24 C ATOM 264 C HIS A 512 -10.341 -14.346 23.174 1.00 58.47 C ANISOU 264 C HIS A 512 7982 5436 8797 -296 -63 -7 C ATOM 265 O HIS A 512 -9.686 -14.478 22.146 1.00 58.80 O ANISOU 265 O HIS A 512 7874 5500 8967 -458 89 106 O ATOM 266 CB HIS A 512 -12.812 -14.747 23.123 1.00 55.76 C ANISOU 266 CB HIS A 512 7833 5280 8073 82 63 59 C ATOM 267 CG HIS A 512 -12.738 -13.712 22.045 1.00 58.02 C ANISOU 267 CG HIS A 512 8189 5394 8463 -17 114 210 C ATOM 268 ND1 HIS A 512 -12.789 -14.024 20.702 1.00 57.76 N ANISOU 268 ND1 HIS A 512 8121 5444 8382 -88 245 391 N ATOM 269 CD2 HIS A 512 -12.618 -12.367 22.114 1.00 60.97 C ANISOU 269 CD2 HIS A 512 8715 5491 8961 -62 45 211 C ATOM 270 CE1 HIS A 512 -12.705 -12.913 19.993 1.00 59.81 C ANISOU 270 CE1 HIS A 512 8532 5481 8712 -178 259 512 C ATOM 271 NE2 HIS A 512 -12.597 -11.896 20.826 1.00 64.33 N ANISOU 271 NE2 HIS A 512 9196 5834 9411 -165 138 408 N ATOM 272 N PHE A 513 -10.128 -13.355 24.034 1.00 60.60 N ANISOU 272 N PHE A 513 8402 5468 9156 -306 -244 -124 N ATOM 273 CA PHE A 513 -9.236 -12.246 23.693 1.00 63.65 C ANISOU 273 CA PHE A 513 8769 5591 9826 -511 -281 -97 C ATOM 274 C PHE A 513 -7.858 -12.731 23.258 1.00 64.81 C ANISOU 274 C PHE A 513 8605 5751 10270 -742 -241 -84 C ATOM 275 O PHE A 513 -7.125 -12.022 22.558 1.00 67.13 O ANISOU 275 O PHE A 513 8814 5868 10826 -949 -132 -1 O ATOM 276 CB PHE A 513 -9.112 -11.240 24.847 1.00 65.81 C ANISOU 276 CB PHE A 513 9250 5592 10165 -489 -541 -267 C ATOM 277 CG PHE A 513 -8.454 -9.936 24.456 1.00 68.52 C ANISOU 277 CG PHE A 513 9612 5624 10799 -680 -575 -223 C ATOM 278 CD1 PHE A 513 -9.160 -8.965 23.750 1.00 69.15 C ANISOU 278 CD1 PHE A 513 9868 5567 10840 -648 -449 -87 C ATOM 279 CD2 PHE A 513 -7.133 -9.679 24.806 1.00 71.03 C ANISOU 279 CD2 PHE A 513 9766 5756 11465 -895 -758 -316 C ATOM 280 CE1 PHE A 513 -8.557 -7.761 23.394 1.00 72.27 C ANISOU 280 CE1 PHE A 513 10309 5650 11499 -836 -475 -32 C ATOM 281 CE2 PHE A 513 -6.520 -8.480 24.456 1.00 73.96 C ANISOU 281 CE2 PHE A 513 10139 5818 12146 -1092 -774 -272 C ATOM 282 CZ PHE A 513 -7.235 -7.519 23.748 1.00 74.68 C ANISOU 282 CZ PHE A 513 10441 5780 12154 -1068 -617 -124 C ATOM 283 N ASN A 514 -7.517 -13.947 23.661 1.00 63.69 N ANISOU 283 N ASN A 514 8287 5798 10115 -708 -307 -164 N ATOM 284 CA ASN A 514 -6.224 -14.504 23.326 1.00 65.19 C ANISOU 284 CA ASN A 514 8130 5988 10651 -898 -275 -183 C ATOM 285 C ASN A 514 -6.009 -14.674 21.822 1.00 65.18 C ANISOU 285 C ASN A 514 7988 6064 10714 -1030 124 -7 C ATOM 286 O ASN A 514 -4.908 -14.424 21.324 1.00 67.63 O ANISOU 286 O ASN A 514 8064 6233 11401 -1253 258 7 O ATOM 287 CB ASN A 514 -6.001 -15.819 24.062 1.00 64.12 C ANISOU 287 CB ASN A 514 7862 6023 10477 -804 -454 -300 C ATOM 288 CG ASN A 514 -4.533 -16.114 24.282 1.00 67.40 C ANISOU 288 CG ASN A 514 7925 6310 11374 -976 -619 -404 C ATOM 289 OD1 ASN A 514 -3.698 -15.865 23.409 1.00 70.46 O ANISOU 289 OD1 ASN A 514 8040 6607 12124 -1173 -397 -347 O ATOM 290 ND2 ASN A 514 -4.205 -16.643 25.456 1.00 68.31 N ANISOU 290 ND2 ASN A 514 8052 6386 11516 -907 -1011 -559 N ATOM 291 N ILE A 515 -7.057 -15.078 21.103 1.00 62.96 N ANISOU 291 N ILE A 515 7867 5977 10078 -901 316 121 N ATOM 292 CA ILE A 515 -7.027 -15.123 19.632 1.00 63.49 C ANISOU 292 CA ILE A 515 7951 6082 10089 -1014 674 300 C ATOM 293 C ILE A 515 -6.276 -13.911 19.055 1.00 66.93 C ANISOU 293 C ILE A 515 8412 6233 10785 -1253 826 385 C ATOM 294 O ILE A 515 -5.543 -14.041 18.074 1.00 68.75 O ANISOU 294 O ILE A 515 8536 6430 11156 -1445 1155 469 O ATOM 295 CB ILE A 515 -8.453 -15.192 19.007 1.00 61.58 C ANISOU 295 CB ILE A 515 8000 5966 9432 -838 732 440 C ATOM 296 CG1 ILE A 515 -9.359 -16.194 19.752 1.00 58.32 C ANISOU 296 CG1 ILE A 515 7574 5784 8799 -597 569 352 C ATOM 297 CG2 ILE A 515 -8.379 -15.499 17.501 1.00 62.39 C ANISOU 297 CG2 ILE A 515 8181 6120 9404 -947 1058 609 C ATOM 298 CD1 ILE A 515 -9.362 -17.612 19.219 1.00 55.81 C ANISOU 298 CD1 ILE A 515 7118 5717 8371 -567 704 366 C ATOM 299 N HIS A 516 -6.452 -12.750 19.687 1.00 68.23 N ANISOU 299 N HIS A 516 8731 6174 11020 -1247 612 355 N ATOM 300 CA HIS A 516 -5.734 -11.525 19.317 1.00 71.94 C ANISOU 300 CA HIS A 516 9226 6329 11779 -1480 704 423 C ATOM 301 C HIS A 516 -4.396 -11.379 20.067 1.00 74.32 C ANISOU 301 C HIS A 516 9189 6454 12596 -1658 555 256 C ATOM 302 O HIS A 516 -3.344 -11.149 19.462 1.00 77.15 O ANISOU 302 O HIS A 516 9325 6657 13330 -1914 798 298 O ATOM 303 CB HIS A 516 -6.600 -10.285 19.599 1.00 72.50 C ANISOU 303 CB HIS A 516 9638 6202 11706 -1382 521 467 C ATOM 304 CG HIS A 516 -8.028 -10.414 19.165 1.00 71.16 C ANISOU 304 CG HIS A 516 9752 6171 11114 -1153 532 582 C ATOM 305 ND1 HIS A 516 -8.390 -10.811 17.896 1.00 71.61 N ANISOU 305 ND1 HIS A 516 9931 6335 10941 -1174 782 773 N ATOM 306 CD2 HIS A 516 -9.186 -10.169 19.826 1.00 70.15 C ANISOU 306 CD2 HIS A 516 9808 6058 10789 -901 318 524 C ATOM 307 CE1 HIS A 516 -9.708 -10.820 17.797 1.00 70.21 C ANISOU 307 CE1 HIS A 516 9971 6230 10477 -943 661 832 C ATOM 308 NE2 HIS A 516 -10.213 -10.426 18.951 1.00 70.93 N ANISOU 308 NE2 HIS A 516 10073 6266 10610 -775 409 682 N ATOM 309 N SER A 517 -4.463 -11.505 21.390 1.00 73.53 N ANISOU 309 N SER A 517 9070 6351 12517 -1522 151 64 N ATOM 310 CA SER A 517 -3.338 -11.287 22.295 1.00 76.03 C ANISOU 310 CA SER A 517 9139 6455 13296 -1652 -150 -117 C ATOM 311 C SER A 517 -2.140 -12.218 22.041 1.00 77.36 C ANISOU 311 C SER A 517 8833 6670 13891 -1802 -44 -174 C ATOM 312 O SER A 517 -1.026 -11.750 21.819 1.00 80.67 O ANISOU 312 O SER A 517 8958 6846 14846 -2047 22 -196 O ATOM 313 CB SER A 517 -3.839 -11.428 23.741 1.00 74.83 C ANISOU 313 CB SER A 517 9188 6320 12926 -1437 -606 -303 C ATOM 314 OG SER A 517 -2.789 -11.352 24.684 1.00 77.33 O ANISOU 314 OG SER A 517 9317 6425 13638 -1539 -994 -490 O ATOM 315 N TRP A 518 -2.392 -13.530 22.060 1.00 75.01 N ANISOU 315 N TRP A 518 8445 6663 13393 -1652 -14 -202 N ATOM 316 CA TRP A 518 -1.347 -14.578 22.073 1.00 76.17 C ANISOU 316 CA TRP A 518 8142 6858 13942 -1725 -11 -303 C ATOM 317 C TRP A 518 -0.427 -14.470 23.296 1.00 78.81 C ANISOU 317 C TRP A 518 8259 6959 14725 -1771 -536 -510 C ATOM 318 O TRP A 518 0.715 -14.927 23.261 1.00 81.36 O ANISOU 318 O TRP A 518 8125 7178 15611 -1901 -568 -600 O ATOM 319 CB TRP A 518 -0.532 -14.620 20.764 1.00 78.49 C ANISOU 319 CB TRP A 518 8135 7101 14588 -1958 521 -203 C ATOM 320 CG TRP A 518 -1.247 -15.261 19.598 1.00 76.14 C ANISOU 320 CG TRP A 518 8014 7066 13849 -1891 979 -44 C ATOM 321 CD1 TRP A 518 -1.789 -14.621 18.516 1.00 76.67 C ANISOU 321 CD1 TRP A 518 8395 7117 13619 -1962 1352 155 C ATOM 322 CD2 TRP A 518 -1.490 -16.659 19.396 1.00 73.17 C ANISOU 322 CD2 TRP A 518 7552 6974 13277 -1744 1067 -72 C ATOM 323 NE1 TRP A 518 -2.359 -15.533 17.658 1.00 74.47 N ANISOU 323 NE1 TRP A 518 8247 7092 12957 -1867 1640 245 N ATOM 324 CE2 TRP A 518 -2.190 -16.790 18.172 1.00 72.12 C ANISOU 324 CE2 TRP A 518 7694 6986 12724 -1734 1487 103 C ATOM 325 CE3 TRP A 518 -1.189 -17.811 20.130 1.00 71.78 C ANISOU 325 CE3 TRP A 518 7122 6918 13235 -1620 799 -225 C ATOM 326 CZ2 TRP A 518 -2.589 -18.028 17.662 1.00 69.96 C ANISOU 326 CZ2 TRP A 518 7431 6975 12175 -1610 1654 114 C ATOM 327 CZ3 TRP A 518 -1.587 -19.042 19.624 1.00 69.95 C ANISOU 327 CZ3 TRP A 518 6887 6951 12741 -1495 990 -204 C ATOM 328 CH2 TRP A 518 -2.281 -19.140 18.398 1.00 68.89 C ANISOU 328 CH2 TRP A 518 7014 6960 12202 -1493 1418 -42 C ATOM 329 N GLU A 519 -0.931 -13.861 24.369 1.00 78.70 N ANISOU 329 N GLU A 519 8587 6839 14477 -1660 -956 -594 N ATOM 330 CA GLU A 519 -0.189 -13.757 25.628 1.00 81.37 C ANISOU 330 CA GLU A 519 8854 6936 15125 -1679 -1545 -799 C ATOM 331 C GLU A 519 0.074 -15.147 26.200 1.00 80.29 C ANISOU 331 C GLU A 519 8564 6950 14994 -1552 -1804 -899 C ATOM 332 O GLU A 519 1.149 -15.403 26.738 1.00 83.38 O ANISOU 332 O GLU A 519 8641 7139 15901 -1637 -2185 -1039 O ATOM 333 CB GLU A 519 -0.925 -12.856 26.635 1.00 81.48 C ANISOU 333 CB GLU A 519 9382 6813 14764 -1563 -1887 -874 C ATOM 334 CG GLU A 519 -0.766 -13.240 28.114 1.00 83.17 C ANISOU 334 CG GLU A 519 9801 6924 14876 -1442 -2504 -1076 C ATOM 335 CD GLU A 519 -0.860 -12.047 29.061 1.00 87.04 C ANISOU 335 CD GLU A 519 10680 7099 15290 -1449 -2891 -1207 C ATOM 336 OE1 GLU A 519 -1.706 -11.144 28.837 1.00 86.23 O ANISOU 336 OE1 GLU A 519 10887 6982 14893 -1401 -2661 -1141 O ATOM 337 OE2 GLU A 519 -0.077 -12.015 30.040 1.00 90.43 O ANISOU 337 OE2 GLU A 519 11120 7270 15970 -1496 -3459 -1386 O ATOM 338 N LYS A 520 -0.903 -16.041 26.072 1.00 76.26 N ANISOU 338 N LYS A 520 8261 6763 13949 -1351 -1622 -826 N ATOM 339 CA LYS A 520 -0.698 -17.444 26.429 1.00 75.23 C ANISOU 339 CA LYS A 520 7981 6788 13815 -1238 -1791 -887 C ATOM 340 C LYS A 520 -0.591 -18.330 25.191 1.00 73.44 C ANISOU 340 C LYS A 520 7422 6791 13689 -1265 -1291 -781 C ATOM 341 O LYS A 520 -1.218 -18.058 24.159 1.00 71.68 O ANISOU 341 O LYS A 520 7298 6713 13223 -1284 -812 -631 O ATOM 342 CB LYS A 520 -1.792 -17.947 27.375 1.00 72.68 C ANISOU 342 CB LYS A 520 8145 6623 12848 -999 -2006 -909 C ATOM 343 CG LYS A 520 -1.565 -17.532 28.819 1.00 76.16 C ANISOU 343 CG LYS A 520 8896 6805 13236 -964 -2606 -1072 C ATOM 344 CD LYS A 520 -2.849 -17.534 29.639 1.00 75.48 C ANISOU 344 CD LYS A 520 9409 6825 12445 -758 -2641 -1077 C ATOM 345 CE LYS A 520 -2.606 -16.903 31.012 1.00 79.74 C ANISOU 345 CE LYS A 520 10353 7055 12888 -746 -3193 -1251 C ATOM 346 NZ LYS A 520 -3.877 -16.636 31.746 1.00 78.95 N ANISOU 346 NZ LYS A 520 10863 7010 12124 -567 -3108 -1271 N ATOM 347 N LYS A 521 0.232 -19.371 25.305 1.00 74.16 N ANISOU 347 N LYS A 521 7143 6881 14152 -1267 -1433 -869 N ATOM 348 CA LYS A 521 0.406 -20.367 24.255 1.00 72.74 C ANISOU 348 CA LYS A 521 6655 6897 14083 -1271 -995 -812 C ATOM 349 C LYS A 521 -0.004 -21.751 24.763 1.00 70.37 C ANISOU 349 C LYS A 521 6438 6798 13502 -1065 -1201 -845 C ATOM 350 O LYS A 521 0.239 -22.101 25.922 1.00 71.47 O ANISOU 350 O LYS A 521 6649 6824 13682 -984 -1745 -954 O ATOM 351 CB LYS A 521 1.860 -20.400 23.784 1.00 76.76 C ANISOU 351 CB LYS A 521 6561 7189 15417 -1469 -888 -899 C ATOM 352 CG LYS A 521 2.365 -19.094 23.200 1.00 79.41 C ANISOU 352 CG LYS A 521 6771 7298 16101 -1710 -618 -856 C ATOM 353 CD LYS A 521 1.961 -18.935 21.744 1.00 77.68 C ANISOU 353 CD LYS A 521 6630 7237 15649 -1794 112 -685 C ATOM 354 CE LYS A 521 2.273 -17.526 21.242 1.00 80.25 C ANISOU 354 CE LYS A 521 6974 7323 16194 -2029 361 -605 C ATOM 355 NZ LYS A 521 3.720 -17.271 21.042 1.00 84.43 N ANISOU 355 NZ LYS A 521 6926 7549 17605 -2275 471 -704 N ATOM 356 N TYR A 522 -0.633 -22.532 23.892 1.00 67.43 N ANISOU 356 N TYR A 522 6096 6698 12828 -988 -785 -746 N ATOM 357 CA TYR A 522 -1.001 -23.906 24.211 1.00 65.03 C ANISOU 357 CA TYR A 522 5832 6577 12300 -813 -915 -764 C ATOM 358 C TYR A 522 -0.446 -24.812 23.124 1.00 65.41 C ANISOU 358 C TYR A 522 5487 6713 12651 -854 -523 -772 C ATOM 359 O TYR A 522 -1.144 -25.118 22.156 1.00 63.12 O ANISOU 359 O TYR A 522 5324 6636 12023 -823 -91 -667 O ATOM 360 CB TYR A 522 -2.522 -24.044 24.334 1.00 61.16 C ANISOU 360 CB TYR A 522 5825 6325 11088 -651 -828 -651 C ATOM 361 CG TYR A 522 -3.123 -23.129 25.377 1.00 60.85 C ANISOU 361 CG TYR A 522 6192 6186 10742 -601 -1126 -662 C ATOM 362 CD1 TYR A 522 -3.157 -23.502 26.720 1.00 61.30 C ANISOU 362 CD1 TYR A 522 6478 6160 10655 -499 -1604 -750 C ATOM 363 CD2 TYR A 522 -3.642 -21.884 25.027 1.00 60.20 C ANISOU 363 CD2 TYR A 522 6307 6063 10503 -655 -929 -589 C ATOM 364 CE1 TYR A 522 -3.700 -22.667 27.684 1.00 61.14 C ANISOU 364 CE1 TYR A 522 6884 6026 10321 -452 -1832 -781 C ATOM 365 CE2 TYR A 522 -4.181 -21.039 25.987 1.00 60.24 C ANISOU 365 CE2 TYR A 522 6686 5953 10250 -598 -1176 -625 C ATOM 366 CZ TYR A 522 -4.209 -21.442 27.310 1.00 61.02 C ANISOU 366 CZ TYR A 522 7017 5978 10189 -497 -1604 -729 C ATOM 367 OH TYR A 522 -4.738 -20.618 28.269 1.00 62.29 O ANISOU 367 OH TYR A 522 7602 6008 10060 -439 -1806 -785 O ATOM 368 N PRO A 523 0.833 -25.215 23.264 1.00 68.70 N ANISOU 368 N PRO A 523 5426 6938 13741 -923 -679 -908 N ATOM 369 CA PRO A 523 1.466 -26.101 22.290 1.00 69.86 C ANISOU 369 CA PRO A 523 5163 7126 14253 -954 -284 -954 C ATOM 370 C PRO A 523 0.965 -27.535 22.420 1.00 67.48 C ANISOU 370 C PRO A 523 4946 7022 13672 -760 -376 -960 C ATOM 371 O PRO A 523 0.727 -28.004 23.531 1.00 66.72 O ANISOU 371 O PRO A 523 5020 6910 13422 -630 -896 -987 O ATOM 372 CB PRO A 523 2.949 -26.036 22.670 1.00 74.63 C ANISOU 372 CB PRO A 523 5208 7411 15738 -1063 -542 -1120 C ATOM 373 CG PRO A 523 2.950 -25.743 24.126 1.00 75.03 C ANISOU 373 CG PRO A 523 5453 7304 15752 -997 -1287 -1174 C ATOM 374 CD PRO A 523 1.750 -24.863 24.367 1.00 71.95 C ANISOU 374 CD PRO A 523 5656 7048 14635 -968 -1266 -1043 C ATOM 375 N CYS A 524 0.806 -28.216 21.289 1.00 66.70 N ANISOU 375 N CYS A 524 4771 7085 13487 -750 130 -932 N ATOM 376 CA CYS A 524 0.505 -29.639 21.276 1.00 65.18 C ANISOU 376 CA CYS A 524 4579 7040 13148 -587 81 -960 C ATOM 377 C CYS A 524 1.708 -30.395 21.810 1.00 68.57 C ANISOU 377 C CYS A 524 4525 7254 14274 -557 -246 -1130 C ATOM 378 O CYS A 524 2.843 -30.106 21.446 1.00 72.51 O ANISOU 378 O CYS A 524 4554 7547 15448 -683 -84 -1240 O ATOM 379 CB CYS A 524 0.187 -30.101 19.857 1.00 64.26 C ANISOU 379 CB CYS A 524 4493 7095 12829 -604 705 -918 C ATOM 380 SG CYS A 524 -0.099 -31.850 19.701 1.00 63.58 S ANISOU 380 SG CYS A 524 4377 7155 12627 -421 686 -973 S ATOM 381 N ARG A 525 1.458 -31.359 22.681 1.00 67.80 N ANISOU 381 N ARG A 525 4538 7177 14045 -394 -710 -1149 N ATOM 382 CA ARG A 525 2.531 -32.170 23.240 1.00 71.44 C ANISOU 382 CA ARG A 525 4579 7410 15154 -336 -1114 -1301 C ATOM 383 C ARG A 525 2.921 -33.327 22.300 1.00 72.21 C ANISOU 383 C ARG A 525 4331 7553 15552 -280 -726 -1390 C ATOM 384 O ARG A 525 3.764 -34.147 22.656 1.00 75.14 O ANISOU 384 O ARG A 525 4325 7734 16491 -204 -1026 -1523 O ATOM 385 CB ARG A 525 2.166 -32.685 24.653 1.00 70.85 C ANISOU 385 CB ARG A 525 4836 7281 14805 -192 -1831 -1277 C ATOM 386 CG ARG A 525 2.130 -31.620 25.790 1.00 72.67 C ANISOU 386 CG ARG A 525 5358 7353 14900 -242 -2333 -1257 C ATOM 387 CD ARG A 525 0.904 -30.669 25.670 1.00 71.41 C ANISOU 387 CD ARG A 525 5708 7409 14015 -276 -2042 -1110 C ATOM 388 NE ARG A 525 0.406 -30.105 26.937 1.00 71.97 N ANISOU 388 NE ARG A 525 6272 7399 13676 -240 -2519 -1076 N ATOM 389 CZ ARG A 525 -0.805 -30.344 27.455 1.00 69.22 C ANISOU 389 CZ ARG A 525 6457 7219 12624 -133 -2540 -968 C ATOM 390 NH1 ARG A 525 -1.664 -31.143 26.829 1.00 65.67 N ANISOU 390 NH1 ARG A 525 6092 7028 11831 -54 -2169 -877 N ATOM 391 NH2 ARG A 525 -1.165 -29.780 28.607 1.00 69.39 N ANISOU 391 NH2 ARG A 525 6938 7129 12299 -110 -2920 -962 N ATOM 392 N TYR A 526 2.332 -33.374 21.101 1.00 70.14 N ANISOU 392 N TYR A 526 4214 7511 14927 -313 -83 -1326 N ATOM 393 CA TYR A 526 2.614 -34.439 20.123 1.00 70.99 C ANISOU 393 CA TYR A 526 4084 7663 15226 -262 347 -1421 C ATOM 394 C TYR A 526 3.164 -33.965 18.775 1.00 73.62 C ANISOU 394 C TYR A 526 4193 7966 15815 -421 1097 -1476 C ATOM 395 O TYR A 526 3.823 -34.730 18.070 1.00 76.18 O ANISOU 395 O TYR A 526 4182 8217 16546 -402 1457 -1620 O ATOM 396 CB TYR A 526 1.382 -35.305 19.884 1.00 66.85 C ANISOU 396 CB TYR A 526 3999 7403 13996 -129 406 -1319 C ATOM 397 CG TYR A 526 0.848 -35.947 21.133 1.00 64.76 C ANISOU 397 CG TYR A 526 3967 7154 13485 19 -232 -1264 C ATOM 398 CD1 TYR A 526 1.474 -37.050 21.695 1.00 66.86 C ANISOU 398 CD1 TYR A 526 3974 7261 14167 140 -610 -1372 C ATOM 399 CD2 TYR A 526 -0.286 -35.447 21.755 1.00 61.85 C ANISOU 399 CD2 TYR A 526 4096 6930 12475 37 -438 -1102 C ATOM 400 CE1 TYR A 526 0.983 -37.640 22.846 1.00 65.60 C ANISOU 400 CE1 TYR A 526 4104 7087 13733 260 -1184 -1301 C ATOM 401 CE2 TYR A 526 -0.788 -36.025 22.900 1.00 60.48 C ANISOU 401 CE2 TYR A 526 4188 6751 12042 155 -946 -1046 C ATOM 402 CZ TYR A 526 -0.151 -37.117 23.439 1.00 62.78 C ANISOU 402 CZ TYR A 526 4273 6883 12696 257 -1318 -1135 C ATOM 403 OH TYR A 526 -0.659 -37.690 24.575 1.00 62.78 O ANISOU 403 OH TYR A 526 4613 6853 12389 359 -1809 -1059 O ATOM 404 N CYS A 527 2.865 -32.724 18.409 1.00 73.27 N ANISOU 404 N CYS A 527 4373 7960 15506 -575 1356 -1362 N ATOM 405 CA CYS A 527 3.495 -32.081 17.261 1.00 76.68 C ANISOU 405 CA CYS A 527 4626 8301 16208 -765 2045 -1394 C ATOM 406 C CYS A 527 3.830 -30.637 17.615 1.00 78.08 C ANISOU 406 C CYS A 527 4755 8326 16586 -942 1957 -1334 C ATOM 407 O CYS A 527 3.340 -30.100 18.599 1.00 75.98 O ANISOU 407 O CYS A 527 4717 8077 16076 -905 1423 -1252 O ATOM 408 CB CYS A 527 2.613 -32.175 16.006 1.00 74.73 C ANISOU 408 CB CYS A 527 4851 8272 15270 -784 2618 -1288 C ATOM 409 SG CYS A 527 0.958 -31.439 16.138 1.00 70.77 S ANISOU 409 SG CYS A 527 5073 8019 13796 -751 2405 -1034 S ATOM 410 N GLU A 528 4.696 -30.016 16.835 1.00 82.38 N ANISOU 410 N GLU A 528 5006 8694 17600 -1142 2498 -1385 N ATOM 411 CA GLU A 528 5.050 -28.629 17.079 1.00 84.47 C ANISOU 411 CA GLU A 528 5213 8785 18096 -1334 2459 -1327 C ATOM 412 C GLU A 528 3.982 -27.746 16.453 1.00 81.53 C ANISOU 412 C GLU A 528 5471 8585 16921 -1408 2742 -1110 C ATOM 413 O GLU A 528 4.144 -27.257 15.337 1.00 84.05 O ANISOU 413 O GLU A 528 5890 8864 17181 -1577 3395 -1053 O ATOM 414 CB GLU A 528 6.438 -28.320 16.516 1.00 90.53 C ANISOU 414 CB GLU A 528 5375 9256 19765 -1539 2947 -1465 C ATOM 415 CG GLU A 528 7.561 -28.652 17.477 1.00 95.03 C ANISOU 415 CG GLU A 528 5266 9549 21292 -1504 2430 -1663 C ATOM 416 CD GLU A 528 8.876 -28.924 16.763 1.00102.99 C ANISOU 416 CD GLU A 528 5581 10296 23255 -1630 3007 -1853 C ATOM 417 OE1 GLU A 528 8.923 -29.882 15.958 1.00104.36 O ANISOU 417 OE1 GLU A 528 5705 10555 23391 -1554 3507 -1934 O ATOM 418 OE2 GLU A 528 9.866 -28.190 17.008 1.00107.80 O ANISOU 418 OE2 GLU A 528 5684 10594 24684 -1807 2973 -1934 O ATOM 419 N LYS A 529 2.890 -27.550 17.181 1.00 76.74 N ANISOU 419 N LYS A 529 5302 8146 15710 -1279 2251 -990 N ATOM 420 CA LYS A 529 1.704 -26.911 16.632 1.00 73.29 C ANISOU 420 CA LYS A 529 5464 7885 14500 -1289 2433 -792 C ATOM 421 C LYS A 529 0.938 -26.295 17.788 1.00 70.02 C ANISOU 421 C LYS A 529 5321 7508 13774 -1200 1830 -715 C ATOM 422 O LYS A 529 0.574 -26.987 18.731 1.00 67.67 O ANISOU 422 O LYS A 529 5054 7295 13361 -1025 1350 -758 O ATOM 423 CB LYS A 529 0.871 -27.962 15.911 1.00 70.70 C ANISOU 423 CB LYS A 529 5435 7799 13626 -1149 2645 -755 C ATOM 424 CG LYS A 529 -0.322 -27.459 15.133 1.00 68.45 C ANISOU 424 CG LYS A 529 5744 7668 12595 -1154 2850 -563 C ATOM 425 CD LYS A 529 -0.583 -28.435 13.993 1.00 68.84 C ANISOU 425 CD LYS A 529 5971 7841 12345 -1111 3270 -578 C ATOM 426 CE LYS A 529 -2.018 -28.404 13.498 1.00 65.80 C ANISOU 426 CE LYS A 529 6170 7643 11188 -1021 3214 -412 C ATOM 427 NZ LYS A 529 -2.279 -29.586 12.613 1.00 65.31 N ANISOU 427 NZ LYS A 529 6257 7693 10864 -943 3470 -465 N ATOM 428 N VAL A 530 0.714 -24.987 17.717 1.00 70.09 N ANISOU 428 N VAL A 530 5549 7430 13651 -1324 1880 -604 N ATOM 429 CA VAL A 530 0.318 -24.211 18.895 1.00 68.42 C ANISOU 429 CA VAL A 530 5505 7159 13331 -1276 1337 -582 C ATOM 430 C VAL A 530 -1.095 -23.659 18.797 1.00 64.90 C ANISOU 430 C VAL A 530 5616 6874 12170 -1189 1314 -416 C ATOM 431 O VAL A 530 -1.534 -23.224 17.731 1.00 64.98 O ANISOU 431 O VAL A 530 5875 6928 11886 -1262 1719 -284 O ATOM 432 CB VAL A 530 1.287 -23.042 19.158 1.00 72.11 C ANISOU 432 CB VAL A 530 5720 7324 14354 -1482 1288 -626 C ATOM 433 CG1 VAL A 530 1.145 -22.565 20.595 1.00 71.40 C ANISOU 433 CG1 VAL A 530 5729 7131 14269 -1407 617 -681 C ATOM 434 CG2 VAL A 530 2.735 -23.456 18.868 1.00 76.26 C ANISOU 434 CG2 VAL A 530 5629 7652 15696 -1617 1495 -777 C ATOM 435 N PHE A 531 -1.797 -23.666 19.924 1.00 62.22 N ANISOU 435 N PHE A 531 5482 6593 11567 -1034 835 -425 N ATOM 436 CA PHE A 531 -3.189 -23.233 19.960 1.00 58.94 C ANISOU 436 CA PHE A 531 5532 6313 10548 -921 792 -295 C ATOM 437 C PHE A 531 -3.391 -22.038 20.894 1.00 58.93 C ANISOU 437 C PHE A 531 5714 6155 10523 -931 474 -299 C ATOM 438 O PHE A 531 -2.658 -21.886 21.875 1.00 60.53 O ANISOU 438 O PHE A 531 5754 6191 11054 -959 118 -422 O ATOM 439 CB PHE A 531 -4.098 -24.404 20.346 1.00 55.74 C ANISOU 439 CB PHE A 531 5270 6136 9773 -711 628 -296 C ATOM 440 CG PHE A 531 -4.069 -25.537 19.358 1.00 55.42 C ANISOU 440 CG PHE A 531 5122 6246 9688 -690 937 -289 C ATOM 441 CD1 PHE A 531 -3.126 -26.557 19.470 1.00 56.52 C ANISOU 441 CD1 PHE A 531 4901 6360 10213 -689 909 -419 C ATOM 442 CD2 PHE A 531 -4.980 -25.584 18.305 1.00 54.19 C ANISOU 442 CD2 PHE A 531 5241 6228 9120 -664 1226 -163 C ATOM 443 CE1 PHE A 531 -3.099 -27.604 18.552 1.00 56.00 C ANISOU 443 CE1 PHE A 531 4758 6415 10105 -661 1212 -433 C ATOM 444 CE2 PHE A 531 -4.961 -26.633 17.378 1.00 53.35 C ANISOU 444 CE2 PHE A 531 5094 6239 8938 -645 1495 -173 C ATOM 445 CZ PHE A 531 -4.024 -27.636 17.501 1.00 54.53 C ANISOU 445 CZ PHE A 531 4893 6372 9455 -643 1513 -313 C ATOM 446 N PRO A 532 -4.379 -21.181 20.582 1.00 57.30 N ANISOU 446 N PRO A 532 5858 5972 9943 -903 574 -172 N ATOM 447 CA PRO A 532 -4.643 -20.005 21.401 1.00 57.52 C ANISOU 447 CA PRO A 532 6090 5834 9932 -900 314 -186 C ATOM 448 C PRO A 532 -5.608 -20.262 22.568 1.00 55.02 C ANISOU 448 C PRO A 532 6036 5604 9266 -690 -11 -236 C ATOM 449 O PRO A 532 -5.733 -19.409 23.445 1.00 55.77 O ANISOU 449 O PRO A 532 6312 5543 9337 -672 -257 -293 O ATOM 450 CB PRO A 532 -5.253 -19.030 20.400 1.00 57.56 C ANISOU 450 CB PRO A 532 6337 5802 9730 -959 606 -22 C ATOM 451 CG PRO A 532 -5.958 -19.904 19.417 1.00 55.74 C ANISOU 451 CG PRO A 532 6197 5800 9183 -879 869 80 C ATOM 452 CD PRO A 532 -5.269 -21.238 19.405 1.00 55.87 C ANISOU 452 CD PRO A 532 5909 5934 9384 -874 910 -18 C ATOM 453 N LEU A 533 -6.270 -21.421 22.567 1.00 52.29 N ANISOU 453 N LEU A 533 5727 5483 8660 -544 16 -219 N ATOM 454 CA LEU A 533 -7.245 -21.792 23.599 1.00 50.34 C ANISOU 454 CA LEU A 533 5733 5321 8075 -358 -195 -252 C ATOM 455 C LEU A 533 -6.961 -23.189 24.108 1.00 49.75 C ANISOU 455 C LEU A 533 5534 5353 8016 -290 -350 -320 C ATOM 456 O LEU A 533 -6.829 -24.119 23.317 1.00 48.98 O ANISOU 456 O LEU A 533 5245 5395 7968 -295 -168 -284 O ATOM 457 CB LEU A 533 -8.681 -21.751 23.049 1.00 47.90 C ANISOU 457 CB LEU A 533 5637 5161 7401 -234 16 -130 C ATOM 458 CG LEU A 533 -9.550 -20.515 23.279 1.00 47.74 C ANISOU 458 CG LEU A 533 5885 5030 7225 -174 14 -96 C ATOM 459 CD1 LEU A 533 -9.008 -19.322 22.539 1.00 49.23 C ANISOU 459 CD1 LEU A 533 6056 5044 7607 -328 114 -37 C ATOM 460 CD2 LEU A 533 -10.984 -20.762 22.876 1.00 45.42 C ANISOU 460 CD2 LEU A 533 5725 4878 6656 -21 157 -1 C ATOM 461 N ALA A 534 -6.893 -23.347 25.427 1.00 50.56 N ANISOU 461 N ALA A 534 5794 5368 8048 -223 -693 -418 N ATOM 462 CA ALA A 534 -6.668 -24.665 26.019 1.00 50.30 C ANISOU 462 CA ALA A 534 5715 5400 7998 -151 -892 -467 C ATOM 463 C ALA A 534 -7.526 -25.737 25.341 1.00 47.93 C ANISOU 463 C ALA A 534 5388 5349 7475 -58 -629 -373 C ATOM 464 O ALA A 534 -7.002 -26.735 24.845 1.00 48.10 O ANISOU 464 O ALA A 534 5157 5444 7676 -74 -588 -381 O ATOM 465 CB ALA A 534 -6.915 -24.639 27.514 1.00 50.88 C ANISOU 465 CB ALA A 534 6147 5356 7827 -67 -1239 -545 C ATOM 466 N GLU A 535 -8.834 -25.513 25.287 1.00 46.56 N ANISOU 466 N GLU A 535 5452 5279 6958 39 -453 -294 N ATOM 467 CA GLU A 535 -9.767 -26.518 24.771 1.00 44.52 C ANISOU 467 CA GLU A 535 5186 5226 6504 131 -262 -212 C ATOM 468 C GLU A 535 -9.536 -26.855 23.296 1.00 44.01 C ANISOU 468 C GLU A 535 4883 5268 6570 67 -17 -150 C ATOM 469 O GLU A 535 -9.820 -27.986 22.858 1.00 43.08 O ANISOU 469 O GLU A 535 4685 5289 6394 114 62 -124 O ATOM 470 CB GLU A 535 -11.211 -26.079 24.983 1.00 43.50 C ANISOU 470 CB GLU A 535 5302 5141 6084 241 -128 -152 C ATOM 471 CG GLU A 535 -11.652 -24.961 24.066 1.00 43.83 C ANISOU 471 CG GLU A 535 5352 5157 6145 217 51 -80 C ATOM 472 CD GLU A 535 -13.135 -24.695 24.155 1.00 43.92 C ANISOU 472 CD GLU A 535 5522 5203 5962 348 173 -25 C ATOM 473 OE1 GLU A 535 -13.606 -24.222 25.222 1.00 44.82 O ANISOU 473 OE1 GLU A 535 5842 5222 5964 421 134 -87 O ATOM 474 OE2 GLU A 535 -13.824 -24.958 23.145 1.00 43.08 O ANISOU 474 OE2 GLU A 535 5338 5196 5834 378 306 69 O ATOM 475 N TYR A 536 -9.030 -25.886 22.535 1.00 44.83 N ANISOU 475 N TYR A 536 4915 5286 6830 -47 115 -128 N ATOM 476 CA TYR A 536 -8.699 -26.139 21.142 1.00 44.78 C ANISOU 476 CA TYR A 536 4760 5342 6911 -129 387 -76 C ATOM 477 C TYR A 536 -7.569 -27.171 21.049 1.00 45.66 C ANISOU 477 C TYR A 536 4579 5458 7313 -178 377 -171 C ATOM 478 O TYR A 536 -7.621 -28.085 20.221 1.00 45.21 O ANISOU 478 O TYR A 536 4441 5514 7222 -165 557 -158 O ATOM 479 CB TYR A 536 -8.368 -24.843 20.393 1.00 46.19 C ANISOU 479 CB TYR A 536 4977 5393 7181 -261 560 -19 C ATOM 480 CG TYR A 536 -9.575 -23.947 20.115 1.00 45.68 C ANISOU 480 CG TYR A 536 5191 5321 6842 -198 602 95 C ATOM 481 CD1 TYR A 536 -10.888 -24.398 20.337 1.00 43.78 C ANISOU 481 CD1 TYR A 536 5090 5201 6341 -35 543 137 C ATOM 482 CD2 TYR A 536 -9.407 -22.660 19.604 1.00 46.54 C ANISOU 482 CD2 TYR A 536 5405 5277 7002 -302 700 163 C ATOM 483 CE1 TYR A 536 -11.982 -23.590 20.081 1.00 42.16 C ANISOU 483 CE1 TYR A 536 5082 4958 5980 37 557 227 C ATOM 484 CE2 TYR A 536 -10.496 -21.849 19.342 1.00 45.71 C ANISOU 484 CE2 TYR A 536 5543 5133 6692 -228 696 265 C ATOM 485 CZ TYR A 536 -11.778 -22.320 19.581 1.00 44.60 C ANISOU 485 CZ TYR A 536 5499 5108 6339 -51 614 289 C ATOM 486 OH TYR A 536 -12.869 -21.511 19.317 1.00 45.98 O ANISOU 486 OH TYR A 536 5862 5211 6395 36 588 378 O ATOM 487 N ARG A 537 -6.576 -27.036 21.923 1.00 47.19 N ANISOU 487 N ARG A 537 4619 5504 7807 -225 136 -277 N ATOM 488 CA ARG A 537 -5.510 -28.021 22.038 1.00 48.50 C ANISOU 488 CA ARG A 537 4474 5629 8325 -244 39 -384 C ATOM 489 C ARG A 537 -6.029 -29.385 22.515 1.00 46.99 C ANISOU 489 C ARG A 537 4343 5563 7950 -101 -116 -390 C ATOM 490 O ARG A 537 -5.635 -30.430 21.976 1.00 47.15 O ANISOU 490 O ARG A 537 4156 5636 8123 -86 -16 -431 O ATOM 491 CB ARG A 537 -4.405 -27.518 22.968 1.00 50.97 C ANISOU 491 CB ARG A 537 4625 5710 9030 -315 -292 -495 C ATOM 492 CG ARG A 537 -3.493 -28.613 23.471 1.00 52.42 C ANISOU 492 CG ARG A 537 4535 5817 9564 -281 -562 -610 C ATOM 493 CD ARG A 537 -2.280 -28.057 24.141 1.00 56.21 C ANISOU 493 CD ARG A 537 4785 6028 10545 -375 -893 -727 C ATOM 494 NE ARG A 537 -2.510 -27.733 25.542 1.00 57.11 N ANISOU 494 NE ARG A 537 5216 6024 10460 -314 -1386 -754 N ATOM 495 CZ ARG A 537 -1.583 -27.219 26.345 1.00 60.30 C ANISOU 495 CZ ARG A 537 5526 6161 11226 -379 -1810 -861 C ATOM 496 NH1 ARG A 537 -0.364 -26.971 25.890 1.00 63.69 N ANISOU 496 NH1 ARG A 537 5478 6414 12309 -512 -1790 -949 N ATOM 497 NH2 ARG A 537 -1.875 -26.952 27.607 1.00 61.08 N ANISOU 497 NH2 ARG A 537 6019 6145 11044 -318 -2251 -887 N ATOM 498 N THR A 538 -6.905 -29.388 23.514 1.00 45.78 N ANISOU 498 N THR A 538 4483 5436 7477 -1 -328 -355 N ATOM 499 CA THR A 538 -7.390 -30.658 24.048 1.00 44.90 C ANISOU 499 CA THR A 538 4457 5410 7193 114 -465 -347 C ATOM 500 C THR A 538 -8.002 -31.542 22.955 1.00 43.52 C ANISOU 500 C THR A 538 4215 5415 6903 152 -183 -289 C ATOM 501 O THR A 538 -7.580 -32.685 22.783 1.00 43.59 O ANISOU 501 O THR A 538 4059 5446 7057 180 -218 -335 O ATOM 502 CB THR A 538 -8.336 -30.473 25.248 1.00 44.15 C ANISOU 502 CB THR A 538 4735 5302 6740 199 -633 -310 C ATOM 503 OG1 THR A 538 -7.628 -29.809 26.294 1.00 45.63 O ANISOU 503 OG1 THR A 538 5027 5288 7023 164 -954 -390 O ATOM 504 CG2 THR A 538 -8.814 -31.806 25.774 1.00 43.08 C ANISOU 504 CG2 THR A 538 4704 5229 6435 291 -732 -283 C ATOM 505 N LYS A 539 -8.955 -31.013 22.192 1.00 42.83 N ANISOU 505 N LYS A 539 4260 5429 6583 154 62 -198 N ATOM 506 CA LYS A 539 -9.595 -31.838 21.152 1.00 42.32 C ANISOU 506 CA LYS A 539 4184 5508 6387 190 264 -148 C ATOM 507 C LYS A 539 -8.618 -32.234 20.069 1.00 43.54 C ANISOU 507 C LYS A 539 4118 5653 6773 114 462 -211 C ATOM 508 O LYS A 539 -8.684 -33.344 19.536 1.00 43.74 O ANISOU 508 O LYS A 539 4080 5751 6789 153 534 -236 O ATOM 509 CB LYS A 539 -10.872 -31.221 20.561 1.00 41.25 C ANISOU 509 CB LYS A 539 4248 5445 5979 219 405 -37 C ATOM 510 CG LYS A 539 -10.730 -29.830 20.015 1.00 43.74 C ANISOU 510 CG LYS A 539 4633 5684 6303 139 528 4 C ATOM 511 CD LYS A 539 -12.025 -29.338 19.392 1.00 44.80 C ANISOU 511 CD LYS A 539 4960 5860 6203 190 601 116 C ATOM 512 CE LYS A 539 -12.179 -29.831 17.941 1.00 47.54 C ANISOU 512 CE LYS A 539 5345 6266 6451 160 761 160 C ATOM 513 NZ LYS A 539 -13.012 -28.890 17.090 1.00 49.34 N ANISOU 513 NZ LYS A 539 5792 6447 6509 159 803 276 N ATOM 514 N HIS A 540 -7.692 -31.343 19.767 1.00 45.13 N ANISOU 514 N HIS A 540 4202 5744 7201 0 572 -248 N ATOM 515 CA HIS A 540 -6.609 -31.707 18.886 1.00 47.27 C ANISOU 515 CA HIS A 540 4228 5966 7768 -84 813 -333 C ATOM 516 C HIS A 540 -5.823 -32.889 19.452 1.00 47.99 C ANISOU 516 C HIS A 540 4050 6011 8173 -26 627 -456 C ATOM 517 O HIS A 540 -5.438 -33.793 18.704 1.00 48.98 O ANISOU 517 O HIS A 540 4029 6158 8424 -17 820 -527 O ATOM 518 CB HIS A 540 -5.677 -30.524 18.676 1.00 49.71 C ANISOU 518 CB HIS A 540 4412 6122 8354 -233 953 -355 C ATOM 519 CG HIS A 540 -4.463 -30.851 17.873 1.00 53.65 C ANISOU 519 CG HIS A 540 4608 6530 9245 -333 1258 -461 C ATOM 520 ND1 HIS A 540 -4.491 -30.957 16.500 1.00 56.10 N ANISOU 520 ND1 HIS A 540 5019 6880 9418 -398 1700 -439 N ATOM 521 CD2 HIS A 540 -3.182 -31.089 18.245 1.00 56.92 C ANISOU 521 CD2 HIS A 540 4624 6792 10212 -379 1198 -601 C ATOM 522 CE1 HIS A 540 -3.278 -31.244 16.059 1.00 59.44 C ANISOU 522 CE1 HIS A 540 5117 7184 10282 -484 1971 -566 C ATOM 523 NE2 HIS A 540 -2.463 -31.315 17.097 1.00 61.81 N ANISOU 523 NE2 HIS A 540 5069 7363 11051 -473 1666 -667 N ATOM 524 N GLU A 541 -5.586 -32.882 20.765 1.00 47.83 N ANISOU 524 N GLU A 541 4000 5903 8269 17 240 -486 N ATOM 525 CA GLU A 541 -4.718 -33.883 21.381 1.00 48.91 C ANISOU 525 CA GLU A 541 3890 5935 8757 68 -23 -598 C ATOM 526 C GLU A 541 -5.380 -35.243 21.542 1.00 47.35 C ANISOU 526 C GLU A 541 3797 5841 8355 192 -123 -575 C ATOM 527 O GLU A 541 -4.730 -36.270 21.344 1.00 48.38 O ANISOU 527 O GLU A 541 3693 5920 8770 232 -147 -669 O ATOM 528 CB GLU A 541 -4.162 -33.391 22.711 1.00 50.24 C ANISOU 528 CB GLU A 541 4053 5927 9110 62 -464 -638 C ATOM 529 CG GLU A 541 -2.978 -32.460 22.568 1.00 53.20 C ANISOU 529 CG GLU A 541 4132 6117 9965 -67 -442 -725 C ATOM 530 CD GLU A 541 -2.256 -32.216 23.877 1.00 56.19 C ANISOU 530 CD GLU A 541 4464 6270 10614 -65 -981 -799 C ATOM 531 OE1 GLU A 541 -2.840 -32.499 24.944 1.00 55.54 O ANISOU 531 OE1 GLU A 541 4712 6187 10203 27 -1337 -756 O ATOM 532 OE2 GLU A 541 -1.097 -31.742 23.846 1.00 59.50 O ANISOU 532 OE2 GLU A 541 4535 6489 11584 -163 -1055 -903 O ATOM 533 N ILE A 542 -6.666 -35.253 21.901 1.00 45.20 N ANISOU 533 N ILE A 542 3852 5690 7633 251 -170 -458 N ATOM 534 CA ILE A 542 -7.441 -36.497 21.964 1.00 43.85 C ANISOU 534 CA ILE A 542 3789 5611 7261 345 -216 -417 C ATOM 535 C ILE A 542 -7.466 -37.107 20.573 1.00 43.91 C ANISOU 535 C ILE A 542 3682 5707 7296 339 102 -453 C ATOM 536 O ILE A 542 -7.481 -38.326 20.409 1.00 43.91 O ANISOU 536 O ILE A 542 3620 5718 7344 402 69 -492 O ATOM 537 CB ILE A 542 -8.878 -36.262 22.474 1.00 41.82 C ANISOU 537 CB ILE A 542 3861 5451 6578 388 -235 -287 C ATOM 538 CG1 ILE A 542 -8.904 -36.285 24.002 1.00 42.69 C ANISOU 538 CG1 ILE A 542 4163 5454 6603 425 -561 -268 C ATOM 539 CG2 ILE A 542 -9.844 -37.321 21.942 1.00 39.79 C ANISOU 539 CG2 ILE A 542 3665 5312 6141 444 -127 -235 C ATOM 540 CD1 ILE A 542 -10.012 -35.387 24.609 1.00 42.63 C ANISOU 540 CD1 ILE A 542 4461 5480 6257 435 -506 -179 C ATOM 541 N HIS A 543 -7.439 -36.241 19.570 1.00 44.40 N ANISOU 541 N HIS A 543 3755 5804 7311 257 405 -442 N ATOM 542 CA HIS A 543 -7.398 -36.702 18.207 1.00 45.14 C ANISOU 542 CA HIS A 543 3828 5949 7374 236 727 -484 C ATOM 543 C HIS A 543 -6.144 -37.520 17.884 1.00 47.18 C ANISOU 543 C HIS A 543 3770 6105 8050 236 829 -647 C ATOM 544 O HIS A 543 -6.268 -38.578 17.278 1.00 47.47 O ANISOU 544 O HIS A 543 3807 6174 8056 290 930 -705 O ATOM 545 CB HIS A 543 -7.591 -35.557 17.225 1.00 45.92 C ANISOU 545 CB HIS A 543 4082 6069 7298 137 1022 -422 C ATOM 546 CG HIS A 543 -7.928 -36.027 15.854 1.00 47.80 C ANISOU 546 CG HIS A 543 4476 6361 7324 125 1303 -431 C ATOM 547 ND1 HIS A 543 -9.220 -36.321 15.475 1.00 47.41 N ANISOU 547 ND1 HIS A 543 4693 6410 6911 182 1226 -339 N ATOM 548 CD2 HIS A 543 -7.139 -36.322 14.790 1.00 51.68 C ANISOU 548 CD2 HIS A 543 4912 6799 7926 65 1652 -536 C ATOM 549 CE1 HIS A 543 -9.216 -36.761 14.225 1.00 50.21 C ANISOU 549 CE1 HIS A 543 5191 6765 7120 157 1463 -383 C ATOM 550 NE2 HIS A 543 -7.966 -36.768 13.785 1.00 52.63 N ANISOU 550 NE2 HIS A 543 5331 6985 7680 87 1757 -504 N ATOM 551 N HIS A 544 -4.962 -37.040 18.288 1.00 48.98 N ANISOU 551 N HIS A 544 3718 6188 8705 180 791 -732 N ATOM 552 CA HIS A 544 -3.695 -37.797 18.172 1.00 51.58 C ANISOU 552 CA HIS A 544 3657 6371 9570 196 837 -906 C ATOM 553 C HIS A 544 -3.801 -39.168 18.827 1.00 50.64 C ANISOU 553 C HIS A 544 3489 6230 9521 334 506 -943 C ATOM 554 O HIS A 544 -3.274 -40.155 18.344 1.00 52.24 O ANISOU 554 O HIS A 544 3492 6372 9985 388 621 -1071 O ATOM 555 CB HIS A 544 -2.568 -37.078 18.913 1.00 54.17 C ANISOU 555 CB HIS A 544 3675 6512 10394 134 651 -973 C ATOM 556 CG HIS A 544 -1.817 -36.073 18.098 1.00 57.85 C ANISOU 556 CG HIS A 544 3972 6899 11110 -19 1065 -1018 C ATOM 557 ND1 HIS A 544 -0.930 -36.432 17.106 1.00 62.30 N ANISOU 557 ND1 HIS A 544 4252 7374 12043 -68 1509 -1160 N ATOM 558 CD2 HIS A 544 -1.767 -34.721 18.175 1.00 58.68 C ANISOU 558 CD2 HIS A 544 4145 6968 11184 -142 1119 -946 C ATOM 559 CE1 HIS A 544 -0.392 -35.343 16.586 1.00 64.83 C ANISOU 559 CE1 HIS A 544 4489 7613 12532 -228 1849 -1159 C ATOM 560 NE2 HIS A 544 -0.877 -34.292 17.222 1.00 64.22 N ANISOU 560 NE2 HIS A 544 4615 7562 12223 -276 1595 -1026 N ATOM 561 N THR A 545 -4.485 -39.192 19.956 1.00 48.55 N ANISOU 561 N THR A 545 3435 5992 9019 388 109 -832 N ATOM 562 CA THR A 545 -4.521 -40.318 20.876 1.00 48.17 C ANISOU 562 CA THR A 545 3395 5873 9034 498 -283 -834 C ATOM 563 C THR A 545 -5.459 -41.439 20.410 1.00 46.49 C ANISOU 563 C THR A 545 3357 5776 8530 568 -195 -794 C ATOM 564 O THR A 545 -5.195 -42.623 20.634 1.00 47.23 O ANISOU 564 O THR A 545 3356 5783 8806 653 -372 -851 O ATOM 565 CB THR A 545 -4.894 -39.776 22.287 1.00 47.43 C ANISOU 565 CB THR A 545 3545 5736 8741 502 -688 -723 C ATOM 566 OG1 THR A 545 -3.793 -39.955 23.184 1.00 49.85 O ANISOU 566 OG1 THR A 545 3655 5814 9470 529 -1096 -807 O ATOM 567 CG2 THR A 545 -6.118 -40.415 22.837 1.00 44.11 C ANISOU 567 CG2 THR A 545 3469 5408 7884 563 -812 -591 C ATOM 568 N GLY A 546 -6.553 -41.056 19.764 1.00 44.23 N ANISOU 568 N GLY A 546 3322 5660 7824 532 41 -697 N ATOM 569 CA GLY A 546 -7.509 -42.015 19.235 1.00 42.90 C ANISOU 569 CA GLY A 546 3315 5586 7399 581 109 -662 C ATOM 570 C GLY A 546 -8.490 -42.551 20.250 1.00 41.24 C ANISOU 570 C GLY A 546 3314 5397 6960 630 -175 -532 C ATOM 571 O GLY A 546 -9.304 -43.405 19.925 1.00 40.47 O ANISOU 571 O GLY A 546 3323 5349 6704 662 -157 -498 O ATOM 572 N GLU A 547 -8.404 -42.061 21.480 1.00 41.41 N ANISOU 572 N GLU A 547 3415 5355 6964 627 -426 -465 N ATOM 573 CA GLU A 547 -9.301 -42.474 22.547 1.00 40.63 C ANISOU 573 CA GLU A 547 3572 5247 6618 656 -635 -337 C ATOM 574 C GLU A 547 -10.718 -42.159 22.116 1.00 38.92 C ANISOU 574 C GLU A 547 3532 5181 6074 632 -421 -230 C ATOM 575 O GLU A 547 -10.955 -41.109 21.511 1.00 38.20 O ANISOU 575 O GLU A 547 3448 5174 5893 589 -230 -220 O ATOM 576 CB GLU A 547 -8.971 -41.736 23.843 1.00 41.31 C ANISOU 576 CB GLU A 547 3799 5230 6668 642 -887 -296 C ATOM 577 CG GLU A 547 -9.908 -42.056 24.972 1.00 41.42 C ANISOU 577 CG GLU A 547 4153 5215 6369 656 -1022 -162 C ATOM 578 CD GLU A 547 -9.497 -41.492 26.327 1.00 44.28 C ANISOU 578 CD GLU A 547 4750 5427 6646 649 -1314 -139 C ATOM 579 OE1 GLU A 547 -8.546 -40.689 26.447 1.00 44.89 O ANISOU 579 OE1 GLU A 547 4712 5425 6918 628 -1449 -223 O ATOM 580 OE2 GLU A 547 -10.163 -41.871 27.307 1.00 46.07 O ANISOU 580 OE2 GLU A 547 5314 5594 6597 656 -1406 -34 O ATOM 581 N ARG A 548 -11.638 -43.081 22.406 1.00 38.47 N ANISOU 581 N ARG A 548 3602 5131 5885 656 -469 -149 N ATOM 582 CA ARG A 548 -13.055 -42.906 22.101 1.00 37.53 C ANISOU 582 CA ARG A 548 3598 5114 5546 637 -311 -50 C ATOM 583 C ARG A 548 -13.906 -42.834 23.376 1.00 37.69 C ANISOU 583 C ARG A 548 3839 5094 5389 630 -357 76 C ATOM 584 O ARG A 548 -14.405 -43.862 23.884 1.00 38.37 O ANISOU 584 O ARG A 548 4015 5119 5447 633 -419 141 O ATOM 585 CB ARG A 548 -13.551 -44.047 21.228 1.00 37.54 C ANISOU 585 CB ARG A 548 3541 5136 5586 652 -274 -71 C ATOM 586 CG ARG A 548 -12.893 -44.138 19.893 1.00 38.58 C ANISOU 586 CG ARG A 548 3541 5297 5820 656 -159 -202 C ATOM 587 CD ARG A 548 -13.576 -45.216 19.107 1.00 40.33 C ANISOU 587 CD ARG A 548 3780 5521 6023 669 -154 -220 C ATOM 588 NE ARG A 548 -13.254 -45.121 17.690 1.00 43.06 N ANISOU 588 NE ARG A 548 4114 5898 6347 662 7 -335 N ATOM 589 CZ ARG A 548 -12.587 -46.046 17.008 1.00 45.28 C ANISOU 589 CZ ARG A 548 4334 6118 6751 694 47 -476 C ATOM 590 NH1 ARG A 548 -12.166 -47.158 17.602 1.00 45.69 N ANISOU 590 NH1 ARG A 548 4291 6070 7000 745 -104 -516 N ATOM 591 NH2 ARG A 548 -12.336 -45.852 15.722 1.00 46.62 N ANISOU 591 NH2 ARG A 548 4573 6305 6837 677 248 -580 N ATOM 592 N ARG A 549 -14.084 -41.617 23.879 1.00 37.32 N ANISOU 592 N ARG A 549 3899 5061 5219 614 -295 107 N ATOM 593 CA ARG A 549 -14.683 -41.405 25.195 1.00 37.79 C ANISOU 593 CA ARG A 549 4220 5050 5088 608 -298 197 C ATOM 594 C ARG A 549 -16.203 -41.403 25.187 1.00 37.38 C ANISOU 594 C ARG A 549 4214 5043 4947 598 -70 290 C ATOM 595 O ARG A 549 -16.826 -41.591 26.241 1.00 38.59 O ANISOU 595 O ARG A 549 4584 5117 4961 585 3 368 O ATOM 596 CB ARG A 549 -14.194 -40.094 25.796 1.00 38.13 C ANISOU 596 CB ARG A 549 4383 5057 5050 600 -332 166 C ATOM 597 CG ARG A 549 -12.719 -40.027 25.996 1.00 39.03 C ANISOU 597 CG ARG A 549 4434 5080 5316 600 -592 74 C ATOM 598 CD ARG A 549 -12.337 -38.664 26.441 1.00 40.07 C ANISOU 598 CD ARG A 549 4660 5168 5396 579 -625 38 C ATOM 599 NE ARG A 549 -12.887 -38.362 27.767 1.00 41.51 N ANISOU 599 NE ARG A 549 5222 5254 5294 583 -655 95 N ATOM 600 CZ ARG A 549 -13.280 -37.151 28.153 1.00 39.78 C ANISOU 600 CZ ARG A 549 5166 5024 4926 577 -540 90 C ATOM 601 NH1 ARG A 549 -13.196 -36.130 27.314 1.00 37.55 N ANISOU 601 NH1 ARG A 549 4686 4817 4762 563 -420 49 N ATOM 602 NH2 ARG A 549 -13.761 -36.967 29.371 1.00 40.64 N ANISOU 602 NH2 ARG A 549 5665 5024 4753 582 -528 125 N ATOM 603 N TYR A 550 -16.801 -41.190 24.018 1.00 35.97 N ANISOU 603 N TYR A 550 3847 4962 4859 602 43 279 N ATOM 604 CA TYR A 550 -18.255 -41.083 23.937 1.00 35.89 C ANISOU 604 CA TYR A 550 3808 4966 4864 601 219 353 C ATOM 605 C TYR A 550 -18.831 -42.416 23.526 1.00 36.00 C ANISOU 605 C TYR A 550 3721 4963 4995 583 189 385 C ATOM 606 O TYR A 550 -18.473 -42.938 22.475 1.00 36.24 O ANISOU 606 O TYR A 550 3629 5032 5108 588 82 325 O ATOM 607 CB TYR A 550 -18.646 -39.977 22.951 1.00 35.28 C ANISOU 607 CB TYR A 550 3615 4957 4831 620 283 332 C ATOM 608 CG TYR A 550 -18.256 -38.609 23.449 1.00 35.60 C ANISOU 608 CG TYR A 550 3765 4987 4775 632 333 312 C ATOM 609 CD1 TYR A 550 -16.921 -38.170 23.403 1.00 35.74 C ANISOU 609 CD1 TYR A 550 3810 5008 4763 616 223 243 C ATOM 610 CD2 TYR A 550 -19.202 -37.767 24.008 1.00 36.24 C ANISOU 610 CD2 TYR A 550 3905 5027 4837 658 495 350 C ATOM 611 CE1 TYR A 550 -16.566 -36.918 23.893 1.00 35.81 C ANISOU 611 CE1 TYR A 550 3923 4980 4705 616 241 220 C ATOM 612 CE2 TYR A 550 -18.860 -36.522 24.494 1.00 36.85 C ANISOU 612 CE2 TYR A 550 4107 5071 4823 673 532 318 C ATOM 613 CZ TYR A 550 -17.550 -36.108 24.438 1.00 36.82 C ANISOU 613 CZ TYR A 550 4150 5071 4770 646 388 257 C ATOM 614 OH TYR A 550 -17.233 -34.875 24.928 1.00 38.49 O ANISOU 614 OH TYR A 550 4486 5226 4913 651 401 222 O ATOM 615 N GLN A 551 -19.699 -42.989 24.349 1.00 36.75 N ANISOU 615 N GLN A 551 3888 4978 5098 553 303 471 N ATOM 616 CA GLN A 551 -20.308 -44.266 23.989 1.00 37.03 C ANISOU 616 CA GLN A 551 3816 4970 5285 519 271 508 C ATOM 617 C GLN A 551 -21.827 -44.210 23.877 1.00 38.11 C ANISOU 617 C GLN A 551 3804 5069 5607 493 449 571 C ATOM 618 O GLN A 551 -22.508 -43.804 24.820 1.00 39.38 O ANISOU 618 O GLN A 551 4044 5168 5752 475 688 634 O ATOM 619 CB GLN A 551 -19.903 -45.350 24.979 1.00 37.99 C ANISOU 619 CB GLN A 551 4127 4977 5329 484 215 564 C ATOM 620 CG GLN A 551 -20.201 -46.753 24.496 1.00 37.90 C ANISOU 620 CG GLN A 551 4010 4907 5485 451 120 580 C ATOM 621 CD GLN A 551 -19.847 -47.819 25.513 1.00 38.80 C ANISOU 621 CD GLN A 551 4347 4873 5521 414 51 658 C ATOM 622 OE1 GLN A 551 -19.678 -48.984 25.162 1.00 38.21 O ANISOU 622 OE1 GLN A 551 4221 4732 5567 403 -98 651 O ATOM 623 NE2 GLN A 551 -19.731 -47.426 26.780 1.00 39.36 N ANISOU 623 NE2 GLN A 551 4712 4869 5373 394 143 732 N ATOM 624 N CYS A 552 -22.348 -44.628 22.728 1.00 37.95 N ANISOU 624 N CYS A 552 3575 5062 5780 492 330 543 N ATOM 625 CA CYS A 552 -23.778 -44.792 22.557 1.00 39.92 C ANISOU 625 CA CYS A 552 3622 5234 6309 461 420 594 C ATOM 626 C CYS A 552 -24.252 -45.922 23.456 1.00 41.67 C ANISOU 626 C CYS A 552 3877 5331 6623 379 558 682 C ATOM 627 O CYS A 552 -23.715 -47.022 23.398 1.00 41.52 O ANISOU 627 O CYS A 552 3931 5278 6565 349 414 681 O ATOM 628 CB CYS A 552 -24.114 -45.094 21.094 1.00 39.98 C ANISOU 628 CB CYS A 552 3459 5250 6482 473 165 535 C ATOM 629 SG CYS A 552 -25.728 -45.858 20.833 1.00 43.24 S ANISOU 629 SG CYS A 552 3585 5507 7338 411 140 585 S ATOM 630 N LEU A 553 -25.250 -45.651 24.291 1.00 43.78 N ANISOU 630 N LEU A 553 4104 5508 7024 340 864 757 N ATOM 631 CA LEU A 553 -25.748 -46.661 25.223 1.00 46.14 C ANISOU 631 CA LEU A 553 4479 5660 7393 238 1076 860 C ATOM 632 C LEU A 553 -26.736 -47.635 24.585 1.00 47.85 C ANISOU 632 C LEU A 553 4393 5768 8020 165 1012 884 C ATOM 633 O LEU A 553 -26.963 -48.715 25.118 1.00 49.58 O ANISOU 633 O LEU A 553 4674 5858 8307 66 1106 967 O ATOM 634 CB LEU A 553 -26.363 -46.013 26.465 1.00 48.23 C ANISOU 634 CB LEU A 553 4877 5841 7607 210 1516 923 C ATOM 635 CG LEU A 553 -25.411 -45.457 27.527 1.00 47.79 C ANISOU 635 CG LEU A 553 5259 5807 7092 237 1598 928 C ATOM 636 CD1 LEU A 553 -26.157 -44.589 28.516 1.00 49.77 C ANISOU 636 CD1 LEU A 553 5628 5974 7308 231 2049 949 C ATOM 637 CD2 LEU A 553 -24.713 -46.584 28.253 1.00 48.61 C ANISOU 637 CD2 LEU A 553 5698 5820 6952 170 1510 1009 C ATOM 638 N ALA A 554 -27.317 -47.259 23.448 1.00 47.92 N ANISOU 638 N ALA A 554 4102 5803 8304 208 820 815 N ATOM 639 CA ALA A 554 -28.238 -48.141 22.725 1.00 49.62 C ANISOU 639 CA ALA A 554 4023 5891 8939 143 661 817 C ATOM 640 C ALA A 554 -27.539 -49.351 22.109 1.00 48.87 C ANISOU 640 C ALA A 554 4032 5793 8742 119 345 780 C ATOM 641 O ALA A 554 -28.104 -50.443 22.068 1.00 50.56 O ANISOU 641 O ALA A 554 4128 5860 9225 25 302 817 O ATOM 642 CB ALA A 554 -28.985 -47.370 21.653 1.00 50.13 C ANISOU 642 CB ALA A 554 3799 5952 9294 208 450 749 C ATOM 643 N CYS A 555 -26.315 -49.172 21.628 1.00 46.64 N ANISOU 643 N CYS A 555 3958 5651 8111 200 142 697 N ATOM 644 CA CYS A 555 -25.649 -50.286 20.958 1.00 46.45 C ANISOU 644 CA CYS A 555 4015 5606 8027 196 -135 629 C ATOM 645 C CYS A 555 -24.173 -50.531 21.331 1.00 44.79 C ANISOU 645 C CYS A 555 4073 5471 7475 245 -168 596 C ATOM 646 O CYS A 555 -23.585 -51.510 20.883 1.00 44.66 O ANISOU 646 O CYS A 555 4113 5411 7445 252 -361 531 O ATOM 647 CB CYS A 555 -25.826 -50.165 19.446 1.00 46.29 C ANISOU 647 CB CYS A 555 3897 5608 8082 242 -452 510 C ATOM 648 SG CYS A 555 -24.910 -48.819 18.736 1.00 45.10 S ANISOU 648 SG CYS A 555 3897 5646 7593 355 -508 418 S ATOM 649 N GLY A 556 -23.592 -49.649 22.143 1.00 43.85 N ANISOU 649 N GLY A 556 4103 5436 7121 283 -3 627 N ATOM 650 CA GLY A 556 -22.238 -49.843 22.681 1.00 43.03 C ANISOU 650 CA GLY A 556 4226 5358 6765 325 -65 605 C ATOM 651 C GLY A 556 -21.127 -49.219 21.848 1.00 41.44 C ANISOU 651 C GLY A 556 4033 5290 6422 416 -206 467 C ATOM 652 O GLY A 556 -19.981 -49.082 22.299 1.00 40.91 O ANISOU 652 O GLY A 556 4093 5243 6207 459 -251 435 O ATOM 653 N LYS A 557 -21.475 -48.854 20.624 1.00 41.01 N ANISOU 653 N LYS A 557 3854 5298 6431 439 -282 388 N ATOM 654 CA LYS A 557 -20.549 -48.274 19.674 1.00 40.20 C ANISOU 654 CA LYS A 557 3784 5299 6192 503 -355 262 C ATOM 655 C LYS A 557 -19.904 -47.015 20.269 1.00 39.07 C ANISOU 655 C LYS A 557 3710 5247 5888 533 -230 277 C ATOM 656 O LYS A 557 -20.593 -46.208 20.869 1.00 39.27 O ANISOU 656 O LYS A 557 3731 5284 5907 520 -100 360 O ATOM 657 CB LYS A 557 -21.335 -47.963 18.399 1.00 40.73 C ANISOU 657 CB LYS A 557 3785 5379 6313 503 -452 217 C ATOM 658 CG LYS A 557 -20.535 -48.081 17.128 1.00 42.13 C ANISOU 658 CG LYS A 557 4061 5588 6359 541 -553 71 C ATOM 659 CD LYS A 557 -21.408 -48.473 15.940 1.00 45.07 C ANISOU 659 CD LYS A 557 4449 5886 6791 524 -753 24 C ATOM 660 CE LYS A 557 -21.431 -49.986 15.747 1.00 47.17 C ANISOU 660 CE LYS A 557 4712 6034 7178 504 -889 -40 C ATOM 661 NZ LYS A 557 -22.316 -50.320 14.589 1.00 49.60 N ANISOU 661 NZ LYS A 557 5064 6242 7541 483 -1139 -96 N ATOM 662 N SER A 558 -18.585 -46.857 20.129 1.00 38.65 N ANISOU 662 N SER A 558 3707 5234 5746 573 -262 186 N ATOM 663 CA SER A 558 -17.873 -45.697 20.713 1.00 37.82 C ANISOU 663 CA SER A 558 3658 5185 5528 591 -184 190 C ATOM 664 C SER A 558 -17.368 -44.699 19.680 1.00 37.23 C ANISOU 664 C SER A 558 3561 5197 5389 607 -135 107 C ATOM 665 O SER A 558 -17.254 -45.021 18.488 1.00 37.59 O ANISOU 665 O SER A 558 3593 5253 5435 612 -158 24 O ATOM 666 CB SER A 558 -16.713 -46.146 21.588 1.00 38.20 C ANISOU 666 CB SER A 558 3765 5166 5584 610 -278 166 C ATOM 667 OG SER A 558 -17.192 -46.822 22.733 1.00 39.65 O ANISOU 667 OG SER A 558 4067 5248 5750 583 -306 277 O ATOM 668 N PHE A 559 -17.061 -43.493 20.158 1.00 36.67 N ANISOU 668 N PHE A 559 3529 5163 5241 608 -59 130 N ATOM 669 CA PHE A 559 -16.812 -42.322 19.312 1.00 36.42 C ANISOU 669 CA PHE A 559 3507 5193 5137 604 19 94 C ATOM 670 C PHE A 559 -15.803 -41.375 19.936 1.00 36.51 C ANISOU 670 C PHE A 559 3536 5206 5130 598 59 71 C ATOM 671 O PHE A 559 -15.668 -41.336 21.167 1.00 36.92 O ANISOU 671 O PHE A 559 3639 5213 5175 603 12 109 O ATOM 672 CB PHE A 559 -18.128 -41.602 19.058 1.00 36.03 C ANISOU 672 CB PHE A 559 3474 5157 5061 605 46 178 C ATOM 673 CG PHE A 559 -19.101 -42.437 18.300 1.00 36.70 C ANISOU 673 CG PHE A 559 3518 5211 5216 604 -51 187 C ATOM 674 CD1 PHE A 559 -19.009 -42.546 16.918 1.00 36.50 C ANISOU 674 CD1 PHE A 559 3561 5187 5121 600 -121 123 C ATOM 675 CD2 PHE A 559 -20.066 -43.183 18.969 1.00 37.19 C ANISOU 675 CD2 PHE A 559 3502 5216 5414 595 -71 255 C ATOM 676 CE1 PHE A 559 -19.891 -43.351 16.207 1.00 37.23 C ANISOU 676 CE1 PHE A 559 3648 5221 5278 596 -276 117 C ATOM 677 CE2 PHE A 559 -20.949 -43.990 18.266 1.00 37.84 C ANISOU 677 CE2 PHE A 559 3516 5241 5619 582 -197 255 C ATOM 678 CZ PHE A 559 -20.859 -44.073 16.878 1.00 37.91 C ANISOU 678 CZ PHE A 559 3598 5249 5558 587 -333 181 C ATOM 679 N ILE A 560 -15.097 -40.613 19.099 1.00 36.50 N ANISOU 679 N ILE A 560 3524 5231 5113 576 142 11 N ATOM 680 CA ILE A 560 -14.038 -39.745 19.600 1.00 36.80 C ANISOU 680 CA ILE A 560 3536 5243 5201 554 165 -25 C ATOM 681 C ILE A 560 -14.555 -38.443 20.197 1.00 36.62 C ANISOU 681 C ILE A 560 3608 5222 5085 548 193 50 C ATOM 682 O ILE A 560 -13.812 -37.781 20.932 1.00 37.21 O ANISOU 682 O ILE A 560 3692 5248 5199 531 156 26 O ATOM 683 CB ILE A 560 -12.952 -39.420 18.540 1.00 37.71 C ANISOU 683 CB ILE A 560 3583 5354 5390 511 303 -124 C ATOM 684 CG1 ILE A 560 -13.577 -38.885 17.257 1.00 38.45 C ANISOU 684 CG1 ILE A 560 3808 5488 5314 484 430 -92 C ATOM 685 CG2 ILE A 560 -12.067 -40.632 18.258 1.00 38.79 C ANISOU 685 CG2 ILE A 560 3586 5450 5704 530 296 -242 C ATOM 686 CD1 ILE A 560 -12.560 -38.276 16.303 1.00 40.90 C ANISOU 686 CD1 ILE A 560 4130 5772 5640 416 642 -161 C ATOM 687 N ASN A 561 -15.801 -38.068 19.884 1.00 36.01 N ANISOU 687 N ASN A 561 3590 5171 4919 566 234 128 N ATOM 688 CA ASN A 561 -16.364 -36.800 20.358 1.00 36.01 C ANISOU 688 CA ASN A 561 3667 5150 4866 578 281 184 C ATOM 689 C ASN A 561 -17.901 -36.703 20.354 1.00 36.21 C ANISOU 689 C ASN A 561 3693 5168 4899 623 303 263 C ATOM 690 O ASN A 561 -18.584 -37.610 19.865 1.00 36.34 O ANISOU 690 O ASN A 561 3645 5194 4968 633 257 281 O ATOM 691 CB ASN A 561 -15.773 -35.643 19.572 1.00 36.45 C ANISOU 691 CB ASN A 561 3755 5197 4897 536 343 169 C ATOM 692 CG ASN A 561 -16.164 -35.664 18.106 1.00 37.57 C ANISOU 692 CG ASN A 561 3942 5358 4976 523 367 190 C ATOM 693 OD1 ASN A 561 -17.197 -36.227 17.709 1.00 37.85 O ANISOU 693 OD1 ASN A 561 3980 5401 5001 561 294 228 O ATOM 694 ND2 ASN A 561 -15.342 -35.024 17.289 1.00 38.75 N ANISOU 694 ND2 ASN A 561 4152 5488 5083 460 464 166 N ATOM 695 N TYR A 562 -18.437 -35.594 20.881 1.00 36.36 N ANISOU 695 N TYR A 562 3762 5143 4911 652 368 296 N ATOM 696 CA TYR A 562 -19.894 -35.417 20.988 1.00 36.60 C ANISOU 696 CA TYR A 562 3734 5131 5043 707 416 353 C ATOM 697 C TYR A 562 -20.534 -35.423 19.620 1.00 36.82 C ANISOU 697 C TYR A 562 3697 5153 5140 719 300 384 C ATOM 698 O TYR A 562 -21.568 -36.065 19.412 1.00 37.55 O ANISOU 698 O TYR A 562 3672 5215 5379 744 248 414 O ATOM 699 CB TYR A 562 -20.267 -34.115 21.704 1.00 37.18 C ANISOU 699 CB TYR A 562 3874 5133 5121 750 523 358 C ATOM 700 CG TYR A 562 -21.753 -33.924 21.931 1.00 38.14 C ANISOU 700 CG TYR A 562 3883 5178 5429 819 620 395 C ATOM 701 CD1 TYR A 562 -22.333 -34.230 23.165 1.00 38.72 C ANISOU 701 CD1 TYR A 562 3976 5201 5536 837 822 392 C ATOM 702 CD2 TYR A 562 -22.587 -33.437 20.917 1.00 38.15 C ANISOU 702 CD2 TYR A 562 3770 5130 5597 866 513 432 C ATOM 703 CE1 TYR A 562 -23.705 -34.063 23.380 1.00 39.31 C ANISOU 703 CE1 TYR A 562 3893 5182 5861 897 977 411 C ATOM 704 CE2 TYR A 562 -23.946 -33.264 21.126 1.00 38.99 C ANISOU 704 CE2 TYR A 562 3702 5133 5978 938 582 451 C ATOM 705 CZ TYR A 562 -24.501 -33.577 22.362 1.00 40.21 C ANISOU 705 CZ TYR A 562 3815 5244 6219 952 846 434 C ATOM 706 OH TYR A 562 -25.857 -33.407 22.573 1.00 42.50 O ANISOU 706 OH TYR A 562 3881 5409 6856 1019 978 440 O ATOM 707 N GLN A 563 -19.913 -34.706 18.694 1.00 36.69 N ANISOU 707 N GLN A 563 3780 5140 5022 693 250 380 N ATOM 708 CA GLN A 563 -20.469 -34.516 17.355 1.00 37.42 C ANISOU 708 CA GLN A 563 3923 5189 5104 701 105 419 C ATOM 709 C GLN A 563 -20.760 -35.837 16.647 1.00 37.52 C ANISOU 709 C GLN A 563 3906 5222 5129 688 -17 400 C ATOM 710 O GLN A 563 -21.842 -36.007 16.113 1.00 38.54 O ANISOU 710 O GLN A 563 3989 5280 5375 724 -187 436 O ATOM 711 CB GLN A 563 -19.540 -33.647 16.513 1.00 37.60 C ANISOU 711 CB GLN A 563 4134 5199 4951 645 129 421 C ATOM 712 CG GLN A 563 -20.023 -33.411 15.115 1.00 39.28 C ANISOU 712 CG GLN A 563 4517 5338 5069 642 -33 473 C ATOM 713 CD GLN A 563 -18.970 -32.769 14.229 1.00 41.12 C ANISOU 713 CD GLN A 563 4993 5550 5081 554 67 477 C ATOM 714 OE1 GLN A 563 -18.110 -32.012 14.702 1.00 41.57 O ANISOU 714 OE1 GLN A 563 5046 5613 5136 508 231 466 O ATOM 715 NE2 GLN A 563 -19.031 -33.064 12.933 1.00 41.83 N ANISOU 715 NE2 GLN A 563 5319 5592 4983 520 -23 492 N ATOM 716 N PHE A 564 -19.809 -36.770 16.660 1.00 36.92 N ANISOU 716 N PHE A 564 3842 5215 4970 641 43 334 N ATOM 717 CA PHE A 564 -19.981 -38.021 15.928 1.00 37.45 C ANISOU 717 CA PHE A 564 3913 5283 5032 629 -70 295 C ATOM 718 C PHE A 564 -20.939 -38.946 16.645 1.00 37.50 C ANISOU 718 C PHE A 564 3739 5267 5244 654 -125 319 C ATOM 719 O PHE A 564 -21.703 -39.671 15.995 1.00 38.42 O ANISOU 719 O PHE A 564 3824 5329 5445 657 -294 319 O ATOM 720 CB PHE A 564 -18.645 -38.718 15.662 1.00 37.16 C ANISOU 720 CB PHE A 564 3931 5299 4891 584 31 199 C ATOM 721 CG PHE A 564 -17.720 -37.943 14.750 1.00 38.56 C ANISOU 721 CG PHE A 564 4285 5471 4894 536 145 169 C ATOM 722 CD1 PHE A 564 -18.223 -37.078 13.782 1.00 39.90 C ANISOU 722 CD1 PHE A 564 4659 5579 4924 527 74 230 C ATOM 723 CD2 PHE A 564 -16.335 -38.095 14.849 1.00 39.90 C ANISOU 723 CD2 PHE A 564 4421 5669 5069 493 325 81 C ATOM 724 CE1 PHE A 564 -17.367 -36.364 12.944 1.00 41.43 C ANISOU 724 CE1 PHE A 564 5066 5744 4930 460 226 219 C ATOM 725 CE2 PHE A 564 -15.466 -37.384 14.006 1.00 40.64 C ANISOU 725 CE2 PHE A 564 4659 5737 5045 427 502 52 C ATOM 726 CZ PHE A 564 -15.987 -36.523 13.052 1.00 41.64 C ANISOU 726 CZ PHE A 564 5037 5806 4977 403 475 128 C ATOM 727 N MET A 565 -20.882 -38.910 17.982 1.00 36.84 N ANISOU 727 N MET A 565 3566 5200 5230 662 18 338 N ATOM 728 CA MET A 565 -21.826 -39.607 18.864 1.00 36.90 C ANISOU 728 CA MET A 565 3432 5162 5425 669 59 381 C ATOM 729 C MET A 565 -23.259 -39.173 18.569 1.00 38.27 C ANISOU 729 C MET A 565 3465 5246 5830 707 -6 433 C ATOM 730 O MET A 565 -24.148 -40.010 18.438 1.00 39.48 O ANISOU 730 O MET A 565 3469 5332 6199 696 -87 450 O ATOM 731 CB MET A 565 -21.477 -39.318 20.328 1.00 36.51 C ANISOU 731 CB MET A 565 3429 5119 5325 669 251 397 C ATOM 732 CG MET A 565 -22.390 -39.949 21.385 1.00 37.17 C ANISOU 732 CG MET A 565 3440 5133 5548 659 390 451 C ATOM 733 SD MET A 565 -23.923 -39.018 21.644 1.00 40.67 S ANISOU 733 SD MET A 565 3723 5481 6250 708 542 496 S ATOM 734 CE MET A 565 -23.299 -37.388 22.052 1.00 39.10 C ANISOU 734 CE MET A 565 3689 5302 5863 757 634 466 C ATOM 735 N SER A 566 -23.480 -37.867 18.476 1.00 38.36 N ANISOU 735 N SER A 566 3500 5230 5845 752 12 453 N ATOM 736 CA SER A 566 -24.813 -37.326 18.248 1.00 40.06 C ANISOU 736 CA SER A 566 3549 5326 6348 809 -70 493 C ATOM 737 C SER A 566 -25.366 -37.647 16.853 1.00 41.40 C ANISOU 737 C SER A 566 3711 5419 6600 814 -413 499 C ATOM 738 O SER A 566 -26.550 -37.983 16.715 1.00 43.04 O ANISOU 738 O SER A 566 3697 5506 7151 836 -549 517 O ATOM 739 CB SER A 566 -24.810 -35.827 18.484 1.00 40.31 C ANISOU 739 CB SER A 566 3634 5322 6358 867 10 507 C ATOM 740 OG SER A 566 -25.989 -35.254 17.972 1.00 42.91 O ANISOU 740 OG SER A 566 3809 5509 6984 938 -153 538 O ATOM 741 N SER A 567 -24.514 -37.556 15.828 1.00 40.84 N ANISOU 741 N SER A 567 3897 5394 6227 786 -548 476 N ATOM 742 CA SER A 567 -24.895 -37.927 14.457 1.00 42.26 C ANISOU 742 CA SER A 567 4200 5486 6371 779 -886 469 C ATOM 743 C SER A 567 -25.315 -39.392 14.373 1.00 42.75 C ANISOU 743 C SER A 567 4137 5522 6584 745 -999 430 C ATOM 744 O SER A 567 -26.264 -39.743 13.659 1.00 44.74 O ANISOU 744 O SER A 567 4331 5636 7032 756 -1318 434 O ATOM 745 CB SER A 567 -23.750 -37.670 13.477 1.00 41.80 C ANISOU 745 CB SER A 567 4503 5479 5900 736 -893 439 C ATOM 746 OG SER A 567 -23.654 -36.297 13.170 1.00 42.17 O ANISOU 746 OG SER A 567 4703 5478 5840 758 -905 497 O ATOM 747 N HIS A 568 -24.601 -40.232 15.117 1.00 41.07 N ANISOU 747 N HIS A 568 3889 5416 6301 702 -774 393 N ATOM 748 CA HIS A 568 -24.881 -41.647 15.154 1.00 41.50 C ANISOU 748 CA HIS A 568 3840 5437 6491 662 -849 361 C ATOM 749 C HIS A 568 -26.254 -41.900 15.767 1.00 42.95 C ANISOU 749 C HIS A 568 3698 5502 7118 665 -870 416 C ATOM 750 O HIS A 568 -27.148 -42.445 15.106 1.00 45.01 O ANISOU 750 O HIS A 568 3849 5630 7624 655 -1154 408 O ATOM 751 CB HIS A 568 -23.800 -42.385 15.923 1.00 39.63 C ANISOU 751 CB HIS A 568 3643 5308 6105 627 -617 324 C ATOM 752 CG HIS A 568 -24.211 -43.752 16.358 1.00 41.31 C ANISOU 752 CG HIS A 568 3714 5465 6516 586 -636 323 C ATOM 753 ND1 HIS A 568 -24.295 -44.819 15.489 1.00 43.00 N ANISOU 753 ND1 HIS A 568 3979 5613 6746 560 -860 258 N ATOM 754 CD2 HIS A 568 -24.584 -44.223 17.571 1.00 42.19 C ANISOU 754 CD2 HIS A 568 3670 5550 6809 556 -452 383 C ATOM 755 CE1 HIS A 568 -24.699 -45.889 16.151 1.00 43.79 C ANISOU 755 CE1 HIS A 568 3926 5650 7062 515 -827 282 C ATOM 756 NE2 HIS A 568 -24.867 -45.555 17.416 1.00 44.49 N ANISOU 756 NE2 HIS A 568 3900 5762 7241 507 -567 366 N ATOM 757 N ILE A 569 -26.424 -41.485 17.017 1.00 42.19 N ANISOU 757 N ILE A 569 3458 5431 7140 675 -563 464 N ATOM 758 CA ILE A 569 -27.675 -41.693 17.723 1.00 43.85 C ANISOU 758 CA ILE A 569 3352 5518 7791 667 -457 510 C ATOM 759 C ILE A 569 -28.869 -41.141 16.935 1.00 46.16 C ANISOU 759 C ILE A 569 3437 5647 8454 719 -744 519 C ATOM 760 O ILE A 569 -29.893 -41.801 16.831 1.00 48.31 O ANISOU 760 O ILE A 569 3435 5770 9149 691 -870 525 O ATOM 761 CB ILE A 569 -27.615 -41.120 19.159 1.00 43.50 C ANISOU 761 CB ILE A 569 3282 5509 7737 677 -33 547 C ATOM 762 CG1 ILE A 569 -26.460 -41.775 19.926 1.00 41.70 C ANISOU 762 CG1 ILE A 569 3281 5396 7168 625 146 543 C ATOM 763 CG2 ILE A 569 -28.947 -41.303 19.883 1.00 45.59 C ANISOU 763 CG2 ILE A 569 3220 5620 8480 662 174 586 C ATOM 764 CD1 ILE A 569 -26.474 -41.545 21.435 1.00 42.14 C ANISOU 764 CD1 ILE A 569 3391 5442 7180 611 530 584 C ATOM 765 N LYS A 570 -28.725 -39.951 16.360 1.00 46.08 N ANISOU 765 N LYS A 570 3558 5637 8314 792 -880 521 N ATOM 766 CA LYS A 570 -29.818 -39.340 15.595 1.00 48.65 C ANISOU 766 CA LYS A 570 3719 5772 8992 859 -1224 536 C ATOM 767 C LYS A 570 -30.152 -40.110 14.329 1.00 50.34 C ANISOU 767 C LYS A 570 4008 5873 9246 830 -1716 508 C ATOM 768 O LYS A 570 -31.311 -40.382 14.062 1.00 53.42 O ANISOU 768 O LYS A 570 4105 6065 10128 841 -1987 510 O ATOM 769 CB LYS A 570 -29.504 -37.894 15.232 1.00 48.26 C ANISOU 769 CB LYS A 570 3866 5727 8746 939 -1286 558 C ATOM 770 CG LYS A 570 -29.816 -36.907 16.317 1.00 48.22 C ANISOU 770 CG LYS A 570 3676 5706 8940 1005 -942 573 C ATOM 771 CD LYS A 570 -29.342 -35.543 15.906 1.00 48.43 C ANISOU 771 CD LYS A 570 3946 5734 8723 1069 -1022 595 C ATOM 772 CE LYS A 570 -29.852 -34.476 16.844 1.00 50.20 C ANISOU 772 CE LYS A 570 3974 5883 9218 1158 -751 592 C ATOM 773 NZ LYS A 570 -29.080 -33.220 16.663 1.00 49.59 N ANISOU 773 NZ LYS A 570 4190 5841 8812 1194 -745 610 N ATOM 774 N SER A 571 -29.141 -40.467 13.551 1.00 49.04 N ANISOU 774 N SER A 571 4236 5809 8589 792 -1830 471 N ATOM 775 CA SER A 571 -29.394 -41.105 12.272 1.00 50.96 C ANISOU 775 CA SER A 571 4663 5925 8775 770 -2304 429 C ATOM 776 C SER A 571 -29.663 -42.610 12.381 1.00 51.37 C ANISOU 776 C SER A 571 4562 5936 9021 694 -2359 378 C ATOM 777 O SER A 571 -30.404 -43.150 11.570 1.00 54.32 O ANISOU 777 O SER A 571 4913 6123 9603 680 -2800 346 O ATOM 778 CB SER A 571 -28.262 -40.815 11.281 1.00 50.11 C ANISOU 778 CB SER A 571 5087 5901 8054 760 -2371 397 C ATOM 779 OG SER A 571 -27.167 -41.686 11.495 1.00 48.11 O ANISOU 779 OG SER A 571 4974 5809 7496 700 -2094 330 O ATOM 780 N VAL A 572 -29.072 -43.286 13.363 1.00 48.93 N ANISOU 780 N VAL A 572 4172 5770 8649 644 -1958 373 N ATOM 781 CA VAL A 572 -29.269 -44.728 13.501 1.00 49.25 C ANISOU 781 CA VAL A 572 4094 5755 8863 566 -1998 337 C ATOM 782 C VAL A 572 -30.382 -45.061 14.477 1.00 50.87 C ANISOU 782 C VAL A 572 3833 5843 9651 526 -1843 397 C ATOM 783 O VAL A 572 -31.141 -45.988 14.238 1.00 53.16 O ANISOU 783 O VAL A 572 3928 5969 10302 466 -2065 379 O ATOM 784 CB VAL A 572 -27.995 -45.464 13.960 1.00 46.83 C ANISOU 784 CB VAL A 572 3987 5619 8186 528 -1702 299 C ATOM 785 CG1 VAL A 572 -28.261 -46.957 14.104 1.00 47.12 C ANISOU 785 CG1 VAL A 572 3909 5564 8432 450 -1769 270 C ATOM 786 CG2 VAL A 572 -26.835 -45.211 13.001 1.00 45.65 C ANISOU 786 CG2 VAL A 572 4262 5568 7515 555 -1770 220 C ATOM 787 N HIS A 573 -30.481 -44.314 15.573 1.00 50.17 N ANISOU 787 N HIS A 573 3581 5819 9662 552 -1441 461 N ATOM 788 CA HIS A 573 -31.474 -44.607 16.606 1.00 52.08 C ANISOU 788 CA HIS A 573 3418 5943 10425 504 -1160 516 C ATOM 789 C HIS A 573 -32.659 -43.625 16.631 1.00 54.88 C ANISOU 789 C HIS A 573 3417 6135 11298 573 -1203 534 C ATOM 790 O HIS A 573 -33.550 -43.741 17.473 1.00 57.00 O ANISOU 790 O HIS A 573 3314 6281 12062 538 -906 567 O ATOM 791 CB HIS A 573 -30.791 -44.701 17.973 1.00 50.16 C ANISOU 791 CB HIS A 573 3279 5842 9936 469 -622 563 C ATOM 792 CG HIS A 573 -29.706 -45.737 18.035 1.00 49.23 C ANISOU 792 CG HIS A 573 3445 5836 9425 411 -609 546 C ATOM 793 ND1 HIS A 573 -29.961 -47.086 17.905 1.00 51.42 N ANISOU 793 ND1 HIS A 573 3647 6009 9882 320 -727 542 N ATOM 794 CD2 HIS A 573 -28.369 -45.628 18.215 1.00 47.29 C ANISOU 794 CD2 HIS A 573 3527 5766 8674 435 -507 524 C ATOM 795 CE1 HIS A 573 -28.830 -47.762 17.994 1.00 49.75 C ANISOU 795 CE1 HIS A 573 3717 5905 9282 304 -700 516 C ATOM 796 NE2 HIS A 573 -27.846 -46.902 18.174 1.00 49.51 N ANISOU 796 NE2 HIS A 573 3916 6043 8852 374 -572 502 N ATOM 797 N SER A 574 -32.682 -42.687 15.685 1.00 55.20 N ANISOU 797 N SER A 574 3577 6144 11250 668 -1568 513 N ATOM 798 CA SER A 574 -33.667 -41.599 15.648 1.00 58.04 C ANISOU 798 CA SER A 574 3639 6339 12074 765 -1659 525 C ATOM 799 C SER A 574 -34.003 -41.038 17.024 1.00 58.43 C ANISOU 799 C SER A 574 3431 6400 12370 787 -1064 552 C ATOM 800 O SER A 574 -35.180 -40.895 17.368 1.00 61.87 O ANISOU 800 O SER A 574 3403 6630 13474 806 -977 548 O ATOM 801 CB SER A 574 -34.967 -41.994 14.937 1.00 62.10 C ANISOU 801 CB SER A 574 3773 6559 13262 761 -2139 504 C ATOM 802 OG SER A 574 -34.794 -43.134 14.131 1.00 62.81 O ANISOU 802 OG SER A 574 4029 6615 13219 678 -2520 468 O ATOM 803 N GLN A 575 -32.977 -40.722 17.805 1.00 55.30 N ANISOU 803 N GLN A 575 3338 6217 11455 783 -658 566 N ATOM 804 CA GLN A 575 -33.183 -40.049 19.067 1.00 55.88 C ANISOU 804 CA GLN A 575 3298 6296 11637 815 -114 576 C ATOM 805 C GLN A 575 -32.239 -38.880 19.210 1.00 53.95 C ANISOU 805 C GLN A 575 3398 6204 10898 895 -19 568 C ATOM 806 O GLN A 575 -31.195 -38.809 18.549 1.00 51.37 O ANISOU 806 O GLN A 575 3424 6022 10073 890 -253 567 O ATOM 807 CB GLN A 575 -32.975 -40.996 20.235 1.00 55.32 C ANISOU 807 CB GLN A 575 3267 6281 11472 699 363 608 C ATOM 808 CG GLN A 575 -33.835 -42.224 20.214 1.00 57.81 C ANISOU 808 CG GLN A 575 3261 6438 12268 591 338 628 C ATOM 809 CD GLN A 575 -33.794 -42.971 21.520 1.00 57.89 C ANISOU 809 CD GLN A 575 3320 6450 12226 476 894 681 C ATOM 810 OE1 GLN A 575 -33.226 -44.057 21.609 1.00 55.66 O ANISOU 810 OE1 GLN A 575 3235 6229 11684 377 862 716 O ATOM 811 NE2 GLN A 575 -34.406 -42.391 22.550 1.00 60.63 N ANISOU 811 NE2 GLN A 575 3518 6704 12813 491 1417 685 N ATOM 812 N ASP A 576 -32.615 -37.975 20.105 1.00 55.70 N ANISOU 812 N ASP A 576 3510 6371 11284 961 360 554 N ATOM 813 CA ASP A 576 -31.875 -36.759 20.377 1.00 54.47 C ANISOU 813 CA ASP A 576 3634 6310 10751 1038 476 537 C ATOM 814 C ASP A 576 -31.202 -36.897 21.739 1.00 53.51 C ANISOU 814 C ASP A 576 3756 6304 10271 983 983 533 C ATOM 815 O ASP A 576 -31.895 -36.977 22.764 1.00 55.79 O ANISOU 815 O ASP A 576 3889 6489 10817 973 1424 521 O ATOM 816 CB ASP A 576 -32.858 -35.591 20.399 1.00 57.30 C ANISOU 816 CB ASP A 576 3708 6475 11588 1170 504 504 C ATOM 817 CG ASP A 576 -32.182 -34.243 20.271 1.00 56.41 C ANISOU 817 CG ASP A 576 3875 6414 11145 1261 446 491 C ATOM 818 OD1 ASP A 576 -30.931 -34.174 20.223 1.00 53.25 O ANISOU 818 OD1 ASP A 576 3872 6203 10159 1211 422 506 O ATOM 819 OD2 ASP A 576 -32.923 -33.236 20.214 1.00 59.39 O ANISOU 819 OD2 ASP A 576 4047 6617 11903 1383 420 462 O ATOM 820 N PRO A 577 -29.854 -36.917 21.763 1.00 50.73 N ANISOU 820 N PRO A 577 3799 6138 9338 946 925 538 N ATOM 821 CA PRO A 577 -29.067 -37.013 22.993 1.00 50.07 C ANISOU 821 CA PRO A 577 4013 6142 8869 899 1281 534 C ATOM 822 C PRO A 577 -29.315 -35.853 23.966 1.00 52.18 C ANISOU 822 C PRO A 577 4348 6334 9143 973 1641 487 C ATOM 823 O PRO A 577 -29.399 -36.087 25.171 1.00 53.77 O ANISOU 823 O PRO A 577 4686 6497 9248 934 2047 482 O ATOM 824 CB PRO A 577 -27.637 -36.979 22.487 1.00 46.83 C ANISOU 824 CB PRO A 577 3915 5901 7978 875 1019 529 C ATOM 825 CG PRO A 577 -27.724 -37.446 21.098 1.00 46.20 C ANISOU 825 CG PRO A 577 3722 5833 7998 866 618 542 C ATOM 826 CD PRO A 577 -28.980 -36.855 20.585 1.00 48.54 C ANISOU 826 CD PRO A 577 3718 5969 8755 944 505 543 C ATOM 827 N SER A 578 -29.461 -34.632 23.453 1.00 53.02 N ANISOU 827 N SER A 578 4397 6393 9354 1078 1499 453 N ATOM 828 CA SER A 578 -29.743 -33.456 24.291 1.00 55.49 C ANISOU 828 CA SER A 578 4765 6606 9713 1166 1820 388 C ATOM 829 C SER A 578 -31.121 -33.531 24.946 1.00 60.05 C ANISOU 829 C SER A 578 5016 6991 10810 1204 2221 354 C ATOM 830 O SER A 578 -31.343 -33.001 26.053 1.00 62.16 O ANISOU 830 O SER A 578 5403 7170 11044 1238 2679 290 O ATOM 831 CB SER A 578 -29.678 -32.192 23.454 1.00 55.08 C ANISOU 831 CB SER A 578 4690 6511 9726 1271 1527 371 C ATOM 832 OG SER A 578 -30.549 -32.315 22.352 1.00 56.46 O ANISOU 832 OG SER A 578 4526 6584 10341 1316 1198 404 O ATOM 833 N GLY A 579 -32.050 -34.172 24.236 1.00 62.16 N ANISOU 833 N GLY A 579 4872 7167 11577 1196 2051 387 N ATOM 834 CA GLY A 579 -33.397 -34.397 24.739 1.00 66.67 C ANISOU 834 CA GLY A 579 5035 7531 12765 1211 2421 356 C ATOM 835 C GLY A 579 -33.414 -35.296 25.963 1.00 68.05 C ANISOU 835 C GLY A 579 5368 7707 12781 1088 2959 375 C ATOM 836 O GLY A 579 -32.936 -36.450 25.926 1.00 66.74 O ANISOU 836 O GLY A 579 5342 7647 12369 961 2856 450 O ATOM 837 N ASP A 580 -33.864 -34.699 27.065 1.00 70.86 N ANISOU 837 N ASP A 580 5780 7934 13208 1129 3532 302 N ATOM 838 CA ASP A 580 -34.554 -35.375 28.176 1.00 74.44 C ANISOU 838 CA ASP A 580 6207 8251 13826 1035 4180 304 C ATOM 839 C ASP A 580 -33.918 -36.533 28.944 1.00 73.41 C ANISOU 839 C ASP A 580 6501 8209 13184 865 4377 395 C ATOM 840 O ASP A 580 -34.128 -36.644 30.159 1.00 76.42 O ANISOU 840 O ASP A 580 7151 8483 13401 806 4982 383 O ATOM 841 CB ASP A 580 -35.975 -35.763 27.759 1.00 78.33 C ANISOU 841 CB ASP A 580 6022 8530 15208 1036 4276 296 C ATOM 842 CG ASP A 580 -37.014 -34.999 28.530 1.00 83.88 C ANISOU 842 CG ASP A 580 6471 8988 16410 1123 4906 181 C ATOM 843 OD1 ASP A 580 -36.703 -33.860 28.948 1.00 84.49 O ANISOU 843 OD1 ASP A 580 6809 9062 16231 1243 5055 88 O ATOM 844 OD2 ASP A 580 -38.135 -35.523 28.723 1.00 88.85 O ANISOU 844 OD2 ASP A 580 6633 9410 17715 1070 5269 172 O ATOM 845 N SER A 581 -33.203 -37.420 28.258 1.00 69.69 N ANISOU 845 N SER A 581 6106 7896 12478 786 3894 484 N ATOM 846 CA SER A 581 -32.594 -38.564 28.931 1.00 68.75 C ANISOU 846 CA SER A 581 6370 7831 11921 636 4013 577 C ATOM 847 C SER A 581 -31.209 -38.878 28.382 1.00 63.88 C ANISOU 847 C SER A 581 6062 7432 10778 623 3459 615 C ATOM 848 O SER A 581 -30.768 -38.266 27.393 1.00 61.47 O ANISOU 848 O SER A 581 5655 7238 10461 712 3012 576 O ATOM 849 CB SER A 581 -33.516 -39.795 28.899 1.00 71.45 C ANISOU 849 CB SER A 581 6373 8039 12736 506 4193 654 C ATOM 850 OG SER A 581 -33.592 -40.358 27.602 1.00 69.78 O ANISOU 850 OG SER A 581 5800 7884 12829 502 3626 680 O ATOM 851 N LYS A 582 -30.524 -39.811 29.043 1.00 62.60 N ANISOU 851 N LYS A 582 6287 7302 10196 512 3510 690 N ATOM 852 CA LYS A 582 -29.128 -40.067 28.738 1.00 58.53 C ANISOU 852 CA LYS A 582 6083 6958 9197 508 3054 707 C ATOM 853 C LYS A 582 -28.959 -41.258 27.812 1.00 56.12 C ANISOU 853 C LYS A 582 5575 6713 9034 445 2674 764 C ATOM 854 O LYS A 582 -29.180 -42.419 28.194 1.00 57.03 O ANISOU 854 O LYS A 582 5733 6749 9188 332 2795 847 O ATOM 855 CB LYS A 582 -28.267 -40.175 30.010 1.00 59.35 C ANISOU 855 CB LYS A 582 6793 7042 8717 459 3221 732 C ATOM 856 CG LYS A 582 -27.446 -38.886 30.325 1.00 58.99 C ANISOU 856 CG LYS A 582 7051 7054 8309 554 3132 640 C ATOM 857 CD LYS A 582 -26.065 -38.865 29.636 1.00 55.76 C ANISOU 857 CD LYS A 582 6728 6811 7646 579 2578 623 C ATOM 858 CE LYS A 582 -25.180 -37.685 30.123 1.00 55.98 C ANISOU 858 CE LYS A 582 7093 6856 7322 641 2496 539 C ATOM 859 NZ LYS A 582 -23.754 -37.733 29.597 1.00 52.35 N ANISOU 859 NZ LYS A 582 6713 6520 6656 643 2009 521 N ATOM 860 N LEU A 583 -28.567 -40.932 26.583 1.00 52.64 N ANISOU 860 N LEU A 583 4951 6395 8656 515 2227 717 N ATOM 861 CA LEU A 583 -28.447 -41.908 25.523 1.00 50.42 C ANISOU 861 CA LEU A 583 4483 6160 8514 477 1845 737 C ATOM 862 C LEU A 583 -27.007 -42.311 25.337 1.00 47.20 C ANISOU 862 C LEU A 583 4375 5888 7670 470 1548 728 C ATOM 863 O LEU A 583 -26.727 -43.310 24.676 1.00 46.38 O ANISOU 863 O LEU A 583 4212 5808 7600 430 1288 738 O ATOM 864 CB LEU A 583 -29.032 -41.358 24.227 1.00 50.09 C ANISOU 864 CB LEU A 583 4086 6120 8826 553 1550 688 C ATOM 865 CG LEU A 583 -30.542 -41.096 24.298 1.00 53.25 C ANISOU 865 CG LEU A 583 4080 6340 9812 566 1772 687 C ATOM 866 CD1 LEU A 583 -30.994 -40.183 23.170 1.00 53.07 C ANISOU 866 CD1 LEU A 583 3797 6293 10073 676 1438 635 C ATOM 867 CD2 LEU A 583 -31.347 -42.392 24.312 1.00 54.59 C ANISOU 867 CD2 LEU A 583 4000 6378 10365 451 1833 742 C ATOM 868 N TYR A 584 -26.097 -41.547 25.937 1.00 45.70 N ANISOU 868 N TYR A 584 4494 5761 7108 510 1585 698 N ATOM 869 CA TYR A 584 -24.668 -41.866 25.877 1.00 43.31 C ANISOU 869 CA TYR A 584 4440 5555 6460 507 1314 678 C ATOM 870 C TYR A 584 -23.935 -41.774 27.210 1.00 43.83 C ANISOU 870 C TYR A 584 4920 5575 6159 486 1436 697 C ATOM 871 O TYR A 584 -24.433 -41.196 28.172 1.00 45.89 O ANISOU 871 O TYR A 584 5349 5749 6337 486 1754 708 O ATOM 872 CB TYR A 584 -23.971 -40.994 24.845 1.00 40.93 C ANISOU 872 CB TYR A 584 4072 5376 6106 578 1051 600 C ATOM 873 CG TYR A 584 -23.802 -39.554 25.253 1.00 40.73 C ANISOU 873 CG TYR A 584 4163 5358 5955 637 1164 559 C ATOM 874 CD1 TYR A 584 -24.880 -38.667 25.221 1.00 40.69 C ANISOU 874 CD1 TYR A 584 3993 5291 6177 689 1350 552 C ATOM 875 CD2 TYR A 584 -22.550 -39.065 25.639 1.00 39.29 C ANISOU 875 CD2 TYR A 584 4231 5221 5476 646 1057 516 C ATOM 876 CE1 TYR A 584 -24.727 -37.338 25.583 1.00 40.70 C ANISOU 876 CE1 TYR A 584 4112 5278 6075 751 1447 503 C ATOM 877 CE2 TYR A 584 -22.380 -37.730 26.000 1.00 39.27 C ANISOU 877 CE2 TYR A 584 4346 5204 5370 693 1135 470 C ATOM 878 CZ TYR A 584 -23.476 -36.873 25.972 1.00 40.37 C ANISOU 878 CZ TYR A 584 4352 5285 5701 747 1340 464 C ATOM 879 OH TYR A 584 -23.315 -35.556 26.333 1.00 40.22 O ANISOU 879 OH TYR A 584 4462 5231 5590 800 1415 410 O ATOM 880 N ARG A 585 -22.749 -42.362 27.253 1.00 42.52 N ANISOU 880 N ARG A 585 4929 5441 5784 473 1167 690 N ATOM 881 CA ARG A 585 -21.859 -42.241 28.400 1.00 43.16 C ANISOU 881 CA ARG A 585 5422 5459 5519 464 1133 696 C ATOM 882 C ARG A 585 -20.599 -41.509 27.941 1.00 40.85 C ANISOU 882 C ARG A 585 5128 5260 5134 521 837 601 C ATOM 883 O ARG A 585 -20.100 -41.755 26.848 1.00 39.02 O ANISOU 883 O ARG A 585 4658 5122 5046 540 624 554 O ATOM 884 CB ARG A 585 -21.520 -43.629 28.943 1.00 44.23 C ANISOU 884 CB ARG A 585 5755 5492 5558 400 1028 777 C ATOM 885 CG ARG A 585 -20.851 -43.650 30.307 1.00 47.59 C ANISOU 885 CG ARG A 585 6691 5782 5610 377 988 815 C ATOM 886 CD ARG A 585 -21.012 -45.022 30.990 1.00 51.78 C ANISOU 886 CD ARG A 585 7468 6154 6054 294 1005 942 C ATOM 887 NE ARG A 585 -20.755 -46.127 30.051 1.00 52.41 N ANISOU 887 NE ARG A 585 7248 6274 6391 291 753 943 N ATOM 888 CZ ARG A 585 -20.681 -47.421 30.387 1.00 54.59 C ANISOU 888 CZ ARG A 585 7673 6414 6657 232 656 1038 C ATOM 889 NH1 ARG A 585 -20.831 -47.800 31.655 1.00 58.34 N ANISOU 889 NH1 ARG A 585 8626 6697 6846 159 785 1161 N ATOM 890 NH2 ARG A 585 -20.444 -48.343 29.455 1.00 52.56 N ANISOU 890 NH2 ARG A 585 7129 6189 6652 245 429 1010 N ATOM 891 N LEU A 586 -20.108 -40.584 28.754 1.00 41.32 N ANISOU 891 N LEU A 586 5461 5274 4966 541 845 564 N ATOM 892 CA LEU A 586 -18.811 -39.960 28.499 1.00 40.00 C ANISOU 892 CA LEU A 586 5304 5150 4743 571 554 477 C ATOM 893 C LEU A 586 -17.823 -40.512 29.510 1.00 41.49 C ANISOU 893 C LEU A 586 5830 5212 4723 550 308 487 C ATOM 894 O LEU A 586 -17.880 -40.179 30.701 1.00 43.90 O ANISOU 894 O LEU A 586 6537 5389 4755 536 368 506 O ATOM 895 CB LEU A 586 -18.877 -38.434 28.598 1.00 39.74 C ANISOU 895 CB LEU A 586 5316 5128 4655 608 656 414 C ATOM 896 CG LEU A 586 -17.559 -37.641 28.561 1.00 39.19 C ANISOU 896 CG LEU A 586 5297 5056 4538 617 386 327 C ATOM 897 CD1 LEU A 586 -16.738 -37.944 27.319 1.00 37.08 C ANISOU 897 CD1 LEU A 586 4707 4893 4491 613 189 286 C ATOM 898 CD2 LEU A 586 -17.813 -36.142 28.649 1.00 38.59 C ANISOU 898 CD2 LEU A 586 5271 4968 4425 648 517 274 C ATOM 899 N HIS A 587 -16.938 -41.380 29.038 1.00 40.52 N ANISOU 899 N HIS A 587 5569 5098 4729 551 21 469 N ATOM 900 CA HIS A 587 -15.945 -41.981 29.893 1.00 41.94 C ANISOU 900 CA HIS A 587 6017 5126 4790 546 -299 476 C ATOM 901 C HIS A 587 -14.968 -40.916 30.356 1.00 42.75 C ANISOU 901 C HIS A 587 6260 5169 4813 565 -520 388 C ATOM 902 O HIS A 587 -14.768 -39.916 29.663 1.00 41.25 O ANISOU 902 O HIS A 587 5837 5083 4753 580 -466 309 O ATOM 903 CB HIS A 587 -15.196 -43.068 29.137 1.00 41.12 C ANISOU 903 CB HIS A 587 5647 5036 4940 564 -547 446 C ATOM 904 CG HIS A 587 -16.054 -44.214 28.708 1.00 40.35 C ANISOU 904 CG HIS A 587 5437 4962 4933 540 -401 523 C ATOM 905 ND1 HIS A 587 -16.575 -45.129 29.596 1.00 41.74 N ANISOU 905 ND1 HIS A 587 5906 4996 4957 494 -361 645 N ATOM 906 CD2 HIS A 587 -16.462 -44.605 27.480 1.00 38.92 C ANISOU 906 CD2 HIS A 587 4908 4903 4977 547 -304 493 C ATOM 907 CE1 HIS A 587 -17.273 -46.031 28.935 1.00 41.47 C ANISOU 907 CE1 HIS A 587 5662 4998 5097 470 -243 686 C ATOM 908 NE2 HIS A 587 -17.220 -45.737 27.647 1.00 39.84 N ANISOU 908 NE2 HIS A 587 5074 4951 5115 506 -229 588 N ATOM 909 N PRO A 588 -14.359 -41.117 31.536 1.00 45.42 N ANISOU 909 N PRO A 588 7010 5312 4937 556 -796 405 N ATOM 910 CA PRO A 588 -13.249 -40.255 31.933 1.00 46.87 C ANISOU 910 CA PRO A 588 7288 5398 5121 570 -1126 306 C ATOM 911 C PRO A 588 -12.196 -40.266 30.835 1.00 45.97 C ANISOU 911 C PRO A 588 6669 5362 5434 593 -1329 204 C ATOM 912 O PRO A 588 -12.160 -41.200 30.040 1.00 45.34 O ANISOU 912 O PRO A 588 6296 5356 5574 608 -1304 213 O ATOM 913 CB PRO A 588 -12.699 -40.947 33.178 1.00 49.81 C ANISOU 913 CB PRO A 588 8143 5518 5265 563 -1505 356 C ATOM 914 CG PRO A 588 -13.850 -41.683 33.738 1.00 50.51 C ANISOU 914 CG PRO A 588 8562 5571 5058 526 -1194 496 C ATOM 915 CD PRO A 588 -14.681 -42.117 32.568 1.00 47.64 C ANISOU 915 CD PRO A 588 7724 5423 4956 524 -836 524 C ATOM 916 N CYS A 589 -11.355 -39.241 30.775 1.00 46.76 N ANISOU 916 N CYS A 589 6673 5430 5665 589 -1496 100 N ATOM 917 CA CYS A 589 -10.282 -39.200 29.794 1.00 46.36 C ANISOU 917 CA CYS A 589 6150 5418 6048 594 -1632 -4 C ATOM 918 C CYS A 589 -9.060 -39.917 30.344 1.00 48.59 C ANISOU 918 C CYS A 589 6431 5485 6545 618 -2131 -53 C ATOM 919 O CYS A 589 -8.464 -39.456 31.312 1.00 50.98 O ANISOU 919 O CYS A 589 6999 5593 6778 610 -2487 -85 O ATOM 920 CB CYS A 589 -9.935 -37.755 29.458 1.00 46.30 C ANISOU 920 CB CYS A 589 6010 5442 6138 560 -1561 -86 C ATOM 921 SG CYS A 589 -8.576 -37.609 28.291 1.00 48.44 S ANISOU 921 SG CYS A 589 5719 5725 6961 536 -1638 -215 S ATOM 922 N ARG A 590 -8.688 -41.039 29.726 1.00 48.12 N ANISOU 922 N ARG A 590 6082 5435 6765 653 -2188 -69 N ATOM 923 CA ARG A 590 -7.594 -41.869 30.233 1.00 50.56 C ANISOU 923 CA ARG A 590 6362 5511 7337 698 -2684 -112 C ATOM 924 C ARG A 590 -6.310 -41.824 29.426 1.00 51.47 C ANISOU 924 C ARG A 590 5932 5580 8045 717 -2813 -270 C ATOM 925 O ARG A 590 -5.272 -42.237 29.907 1.00 54.39 O ANISOU 925 O ARG A 590 6221 5715 8731 757 -3277 -334 O ATOM 926 CB ARG A 590 -8.039 -43.325 30.341 1.00 50.59 C ANISOU 926 CB ARG A 590 6482 5479 7261 736 -2715 -18 C ATOM 927 CG ARG A 590 -8.256 -44.054 29.010 1.00 48.12 C ANISOU 927 CG ARG A 590 5748 5339 7198 759 -2401 -56 C ATOM 928 CD ARG A 590 -8.823 -45.439 29.282 1.00 47.71 C ANISOU 928 CD ARG A 590 5885 5221 7021 784 -2450 52 C ATOM 929 NE ARG A 590 -9.239 -46.157 28.084 1.00 45.11 N ANISOU 929 NE ARG A 590 5245 5044 6851 799 -2152 21 N ATOM 930 CZ ARG A 590 -9.853 -47.336 28.113 1.00 44.89 C ANISOU 930 CZ ARG A 590 5328 4980 6749 806 -2132 107 C ATOM 931 NH1 ARG A 590 -10.122 -47.913 29.276 1.00 45.94 N ANISOU 931 NH1 ARG A 590 5880 4933 6642 792 -2352 245 N ATOM 932 NH2 ARG A 590 -10.191 -47.946 26.984 1.00 42.97 N ANISOU 932 NH2 ARG A 590 4815 4855 6658 819 -1897 56 N ATOM 933 N SER A 591 -6.383 -41.349 28.191 1.00 49.79 N ANISOU 933 N SER A 591 5352 5565 8001 687 -2398 -332 N ATOM 934 CA SER A 591 -5.275 -41.495 27.264 1.00 50.92 C ANISOU 934 CA SER A 591 4972 5672 8703 698 -2372 -481 C ATOM 935 C SER A 591 -4.265 -40.362 27.340 1.00 53.32 C ANISOU 935 C SER A 591 5060 5862 9338 642 -2506 -588 C ATOM 936 O SER A 591 -3.208 -40.434 26.727 1.00 54.94 O ANISOU 936 O SER A 591 4808 5981 10087 640 -2502 -724 O ATOM 937 CB SER A 591 -5.809 -41.600 25.856 1.00 48.32 C ANISOU 937 CB SER A 591 4424 5576 8359 681 -1846 -497 C ATOM 938 OG SER A 591 -6.315 -40.348 25.449 1.00 46.41 O ANISOU 938 OG SER A 591 4242 5483 7910 607 -1541 -466 O ATOM 939 N LEU A 592 -4.614 -39.306 28.069 1.00 54.09 N ANISOU 939 N LEU A 592 5476 5945 9130 591 -2589 -536 N ATOM 940 CA LEU A 592 -3.696 -38.201 28.359 1.00 56.95 C ANISOU 940 CA LEU A 592 5705 6153 9781 529 -2807 -630 C ATOM 941 C LEU A 592 -4.068 -37.512 29.676 1.00 58.69 C ANISOU 941 C LEU A 592 6459 6255 9585 514 -3122 -572 C ATOM 942 O LEU A 592 -5.074 -37.841 30.301 1.00 57.92 O ANISOU 942 O LEU A 592 6827 6213 8968 546 -3082 -456 O ATOM 943 CB LEU A 592 -3.642 -37.200 27.199 1.00 55.28 C ANISOU 943 CB LEU A 592 5188 6093 9722 441 -2330 -675 C ATOM 944 CG LEU A 592 -4.941 -36.552 26.740 1.00 52.24 C ANISOU 944 CG LEU A 592 5057 5952 8839 412 -1884 -565 C ATOM 945 CD1 LEU A 592 -5.317 -35.429 27.671 1.00 53.25 C ANISOU 945 CD1 LEU A 592 5553 6017 8664 379 -2030 -528 C ATOM 946 CD2 LEU A 592 -4.803 -36.025 25.334 1.00 51.05 C ANISOU 946 CD2 LEU A 592 4587 5932 8876 343 -1419 -599 C ATOM 947 N GLN A 593 -3.256 -36.549 30.092 1.00 62.12 N ANISOU 947 N GLN A 593 6839 6508 10258 458 -3413 -661 N ATOM 948 CA GLN A 593 -3.459 -35.882 31.372 1.00 64.58 C ANISOU 948 CA GLN A 593 7692 6656 10190 445 -3768 -639 C ATOM 949 C GLN A 593 -4.225 -34.561 31.254 1.00 63.39 C ANISOU 949 C GLN A 593 7740 6640 9706 384 -3404 -615 C ATOM 950 O GLN A 593 -3.616 -33.519 31.011 1.00 64.68 O ANISOU 950 O GLN A 593 7685 6728 10160 308 -3432 -700 O ATOM 951 CB GLN A 593 -2.108 -35.652 32.044 1.00 68.74 C ANISOU 951 CB GLN A 593 8098 6840 11182 427 -4427 -763 C ATOM 952 CG GLN A 593 -2.216 -35.293 33.503 1.00 71.77 C ANISOU 952 CG GLN A 593 9148 6986 11135 433 -4936 -747 C ATOM 953 CD GLN A 593 -0.858 -35.153 34.156 1.00 77.17 C ANISOU 953 CD GLN A 593 9709 7290 12321 419 -5692 -874 C ATOM 954 OE1 GLN A 593 -0.052 -36.087 34.142 1.00 79.02 O ANISOU 954 OE1 GLN A 593 9644 7360 13020 475 -6066 -914 O ATOM 955 NE2 GLN A 593 -0.593 -33.981 34.732 1.00 78.82 N ANISOU 955 NE2 GLN A 593 10136 7330 12481 350 -5952 -949 N ATOM 956 N ILE A 594 -5.552 -34.605 31.404 1.00 61.73 N ANISOU 956 N ILE A 594 7911 6604 8941 416 -3057 -503 N ATOM 957 CA ILE A 594 -6.347 -33.373 31.617 1.00 61.47 C ANISOU 957 CA ILE A 594 8173 6628 8555 387 -2802 -488 C ATOM 958 C ILE A 594 -7.114 -33.410 32.939 1.00 63.17 C ANISOU 958 C ILE A 594 9073 6738 8190 426 -2912 -438 C ATOM 959 O ILE A 594 -7.071 -34.408 33.657 1.00 64.91 O ANISOU 959 O ILE A 594 9571 6849 8242 465 -3174 -391 O ATOM 960 CB ILE A 594 -7.352 -33.056 30.472 1.00 57.86 C ANISOU 960 CB ILE A 594 7514 6456 8012 384 -2189 -419 C ATOM 961 CG1 ILE A 594 -8.232 -34.267 30.159 1.00 56.14 C ANISOU 961 CG1 ILE A 594 7311 6408 7610 444 -1941 -315 C ATOM 962 CG2 ILE A 594 -6.630 -32.494 29.241 1.00 57.57 C ANISOU 962 CG2 ILE A 594 6957 6479 8439 313 -2023 -476 C ATOM 963 CD1 ILE A 594 -9.667 -33.882 29.736 1.00 54.26 C ANISOU 963 CD1 ILE A 594 7176 6366 7075 465 -1455 -230 C ATOM 964 N ARG A 595 -7.807 -32.315 33.257 1.00 63.45 N ANISOU 964 N ARG A 595 9404 6783 7920 415 -2693 -450 N ATOM 965 CA ARG A 595 -8.723 -32.270 34.403 1.00 65.11 C ANISOU 965 CA ARG A 595 10279 6912 7547 452 -2619 -411 C ATOM 966 C ARG A 595 -9.780 -33.383 34.316 1.00 63.89 C ANISOU 966 C ARG A 595 10211 6916 7148 497 -2261 -278 C ATOM 967 O ARG A 595 -10.293 -33.684 33.224 1.00 60.71 O ANISOU 967 O ARG A 595 9384 6747 6936 507 -1893 -222 O ATOM 968 CB ARG A 595 -9.414 -30.911 34.463 1.00 64.73 C ANISOU 968 CB ARG A 595 10401 6886 7308 449 -2305 -458 C ATOM 969 CG ARG A 595 -10.340 -30.728 35.657 1.00 66.51 C ANISOU 969 CG ARG A 595 11322 6998 6951 487 -2152 -453 C ATOM 970 CD ARG A 595 -11.230 -29.517 35.462 1.00 65.12 C ANISOU 970 CD ARG A 595 11183 6886 6672 512 -1713 -494 C ATOM 971 NE ARG A 595 -10.464 -28.275 35.431 1.00 65.51 N ANISOU 971 NE ARG A 595 11177 6800 6913 469 -1970 -617 N ATOM 972 CZ ARG A 595 -10.896 -27.148 34.878 1.00 64.66 C ANISOU 972 CZ ARG A 595 10900 6750 6916 476 -1680 -653 C ATOM 973 NH1 ARG A 595 -12.088 -27.107 34.293 1.00 62.57 N ANISOU 973 NH1 ARG A 595 10485 6676 6613 536 -1156 -581 N ATOM 974 NH2 ARG A 595 -10.132 -26.061 34.900 1.00 65.88 N ANISOU 974 NH2 ARG A 595 11025 6749 7258 422 -1945 -760 N ATOM 975 N GLN A 596 -10.100 -33.983 35.466 1.00 66.71 N ANISOU 975 N GLN A 596 11149 7118 7078 513 -2380 -227 N ATOM 976 CA GLN A 596 -11.044 -35.107 35.522 1.00 66.42 C ANISOU 976 CA GLN A 596 11234 7179 6824 533 -2067 -92 C ATOM 977 C GLN A 596 -12.248 -34.806 36.414 1.00 68.09 C ANISOU 977 C GLN A 596 12020 7339 6511 538 -1663 -53 C ATOM 978 O GLN A 596 -12.101 -34.601 37.634 1.00 71.64 O ANISOU 978 O GLN A 596 13126 7547 6549 527 -1871 -81 O ATOM 979 CB GLN A 596 -10.336 -36.379 35.995 1.00 68.34 C ANISOU 979 CB GLN A 596 11624 7264 7080 535 -2524 -35 C ATOM 980 CG GLN A 596 -11.184 -37.643 35.898 1.00 68.16 C ANISOU 980 CG GLN A 596 11640 7332 6927 541 -2231 110 C ATOM 981 CD GLN A 596 -10.325 -38.889 35.746 1.00 69.94 C ANISOU 981 CD GLN A 596 11684 7470 7420 559 -2664 146 C ATOM 982 OE1 GLN A 596 -9.670 -39.080 34.707 1.00 68.09 O ANISOU 982 OE1 GLN A 596 10839 7348 7684 579 -2753 87 O ATOM 983 NE2 GLN A 596 -10.317 -39.744 36.778 1.00 71.83 N ANISOU 983 NE2 GLN A 596 12477 7485 7329 552 -2920 242 N ATOM 984 N TYR A 597 -13.436 -34.802 35.808 1.00 65.94 N ANISOU 984 N TYR A 597 11515 7269 6269 555 -1089 4 N ATOM 985 CA TYR A 597 -14.647 -34.399 36.532 1.00 67.64 C ANISOU 985 CA TYR A 597 12159 7436 6104 565 -603 17 C ATOM 986 C TYR A 597 -15.235 -35.492 37.407 1.00 70.14 C ANISOU 986 C TYR A 597 12954 7640 6057 535 -441 135 C ATOM 987 O TYR A 597 -15.536 -36.590 36.929 1.00 68.75 O ANISOU 987 O TYR A 597 12516 7566 6040 519 -345 248 O ATOM 988 CB TYR A 597 -15.698 -33.807 35.585 1.00 64.98 C ANISOU 988 CB TYR A 597 11365 7310 6016 602 -85 13 C ATOM 989 CG TYR A 597 -15.366 -32.386 35.198 1.00 63.79 C ANISOU 989 CG TYR A 597 11047 7170 6021 627 -146 -108 C ATOM 990 CD1 TYR A 597 -15.289 -31.377 36.169 1.00 66.60 C ANISOU 990 CD1 TYR A 597 11899 7329 6075 638 -176 -218 C ATOM 991 CD2 TYR A 597 -15.095 -32.050 33.877 1.00 59.76 C ANISOU 991 CD2 TYR A 597 9935 6837 5934 632 -182 -114 C ATOM 992 CE1 TYR A 597 -14.967 -30.063 35.822 1.00 65.82 C ANISOU 992 CE1 TYR A 597 11654 7215 6141 654 -250 -328 C ATOM 993 CE2 TYR A 597 -14.772 -30.744 33.521 1.00 59.28 C ANISOU 993 CE2 TYR A 597 9750 6759 6015 639 -234 -207 C ATOM 994 CZ TYR A 597 -14.710 -29.760 34.492 1.00 62.37 C ANISOU 994 CZ TYR A 597 10592 6956 6148 650 -276 -312 C ATOM 995 OH TYR A 597 -14.395 -28.469 34.135 1.00 62.50 O ANISOU 995 OH TYR A 597 10485 6935 6328 650 -337 -401 O ATOM 996 N ALA A 598 -15.388 -35.165 38.691 1.00 74.23 N ANISOU 996 N ALA A 598 14213 7924 6068 520 -404 107 N ATOM 997 CA ALA A 598 -15.899 -36.076 39.725 1.00 77.80 C ANISOU 997 CA ALA A 598 15301 8200 6060 470 -229 221 C ATOM 998 C ALA A 598 -17.306 -36.645 39.445 1.00 77.18 C ANISOU 998 C ALA A 598 15027 8247 6051 450 478 328 C ATOM 999 O ALA A 598 -17.784 -37.527 40.183 1.00 80.18 O ANISOU 999 O ALA A 598 15864 8489 6113 387 691 448 O ATOM 1000 CB ALA A 598 -15.864 -35.378 41.101 1.00 82.46 C ANISOU 1000 CB ALA A 598 16781 8502 6048 458 -245 141 C ATOM 1001 N TYR A 599 -17.961 -36.132 38.400 1.00 73.76 N ANISOU 1001 N TYR A 599 13937 8043 6044 495 818 288 N ATOM 1002 CA TYR A 599 -19.294 -36.592 38.011 1.00 73.03 C ANISOU 1002 CA TYR A 599 13543 8058 6148 481 1426 369 C ATOM 1003 C TYR A 599 -19.235 -37.559 36.828 1.00 69.40 C ANISOU 1003 C TYR A 599 12435 7796 6138 472 1274 460 C ATOM 1004 O TYR A 599 -20.129 -38.390 36.655 1.00 69.75 O ANISOU 1004 O TYR A 599 12321 7871 6310 430 1619 563 O ATOM 1005 CB TYR A 599 -20.232 -35.408 37.709 1.00 72.67 C ANISOU 1005 CB TYR A 599 13246 8078 6286 547 1908 263 C ATOM 1006 CG TYR A 599 -19.959 -34.654 36.419 1.00 68.84 C ANISOU 1006 CG TYR A 599 12095 7798 6262 615 1706 192 C ATOM 1007 CD1 TYR A 599 -19.372 -33.381 36.441 1.00 68.94 C ANISOU 1007 CD1 TYR A 599 12177 7777 6239 665 1502 58 C ATOM 1008 CD2 TYR A 599 -20.310 -35.201 35.165 1.00 66.26 C ANISOU 1008 CD2 TYR A 599 11111 7675 6392 621 1722 261 C ATOM 1009 CE1 TYR A 599 -19.126 -32.661 35.233 1.00 65.54 C ANISOU 1009 CE1 TYR A 599 11176 7511 6214 711 1347 12 C ATOM 1010 CE2 TYR A 599 -20.067 -34.495 33.951 1.00 62.68 C ANISOU 1010 CE2 TYR A 599 10129 7384 6302 674 1549 208 C ATOM 1011 CZ TYR A 599 -19.475 -33.230 34.002 1.00 62.77 C ANISOU 1011 CZ TYR A 599 10229 7357 6263 714 1380 92 C ATOM 1012 OH TYR A 599 -19.239 -32.538 32.832 1.00 60.51 O ANISOU 1012 OH TYR A 599 9483 7203 6304 748 1240 60 O ATOM 1013 N LEU A 600 -18.174 -37.443 36.029 1.00 66.23 N ANISOU 1013 N LEU A 600 11674 7506 5985 504 775 411 N ATOM 1014 CA LEU A 600 -17.997 -38.209 34.798 1.00 62.44 C ANISOU 1014 CA LEU A 600 10591 7210 5923 508 623 458 C ATOM 1015 C LEU A 600 -17.990 -39.731 34.996 1.00 63.12 C ANISOU 1015 C LEU A 600 10777 7234 5972 453 533 589 C ATOM 1016 O LEU A 600 -17.248 -40.261 35.822 1.00 65.01 O ANISOU 1016 O LEU A 600 11458 7297 5947 427 198 627 O ATOM 1017 CB LEU A 600 -16.704 -37.767 34.122 1.00 60.27 C ANISOU 1017 CB LEU A 600 10034 7003 5862 540 138 366 C ATOM 1018 CG LEU A 600 -16.777 -37.540 32.617 1.00 56.66 C ANISOU 1018 CG LEU A 600 8925 6769 5833 570 187 334 C ATOM 1019 CD1 LEU A 600 -18.187 -37.127 32.170 1.00 55.96 C ANISOU 1019 CD1 LEU A 600 8625 6777 5859 591 673 356 C ATOM 1020 CD2 LEU A 600 -15.754 -36.484 32.232 1.00 55.38 C ANISOU 1020 CD2 LEU A 600 8620 6626 5797 589 -91 221 C TER 1021 LEU A 600 ATOM 1022 O5' DG D 1 -30.196 -20.920 -2.346 1.00 96.14 O ANISOU 1022 O5' DG D 1 13754 15361 7415 2705 -2995 3212 O ATOM 1023 C5' DG D 1 -30.612 -21.131 -1.012 1.00 92.12 C ANISOU 1023 C5' DG D 1 12715 14791 7494 2805 -2893 3053 C ATOM 1024 C4' DG D 1 -30.332 -22.573 -0.652 1.00 88.02 C ANISOU 1024 C4' DG D 1 11878 14386 7178 2216 -2762 2554 C ATOM 1025 O4' DG D 1 -28.915 -22.761 -0.422 1.00 83.25 O ANISOU 1025 O4' DG D 1 11683 13254 6693 1877 -2272 2371 O ATOM 1026 C3' DG D 1 -30.962 -23.068 0.635 1.00 85.47 C ANISOU 1026 C3' DG D 1 10932 14149 7394 2233 -2723 2361 C ATOM 1027 O3' DG D 1 -31.045 -24.477 0.533 1.00 84.64 O ANISOU 1027 O3' DG D 1 10543 14318 7300 1695 -2774 1960 O ATOM 1028 C2' DG D 1 -29.957 -22.611 1.695 1.00 79.68 C ANISOU 1028 C2' DG D 1 10456 12765 7054 2270 -2228 2340 C ATOM 1029 C1' DG D 1 -28.634 -22.840 0.970 1.00 77.52 C ANISOU 1029 C1' DG D 1 10730 12196 6526 1883 -1968 2229 C ATOM 1030 N9 DG D 1 -27.564 -21.871 1.210 1.00 75.21 N ANISOU 1030 N9 DG D 1 10941 11332 6304 1984 -1600 2393 N ATOM 1031 C8 DG D 1 -27.644 -20.497 1.256 1.00 77.23 C ANISOU 1031 C8 DG D 1 11512 11308 6524 2427 -1577 2767 C ATOM 1032 N7 DG D 1 -26.490 -19.917 1.464 1.00 74.78 N ANISOU 1032 N7 DG D 1 11647 10478 6289 2311 -1192 2799 N ATOM 1033 C5 DG D 1 -25.585 -20.970 1.551 1.00 70.77 C ANISOU 1033 C5 DG D 1 11070 9947 5874 1803 -958 2438 C ATOM 1034 C6 DG D 1 -24.179 -20.983 1.761 1.00 67.30 C ANISOU 1034 C6 DG D 1 10901 9117 5551 1475 -536 2296 C ATOM 1035 O6 DG D 1 -23.414 -20.030 1.923 1.00 67.43 O ANISOU 1035 O6 DG D 1 11295 8715 5610 1498 -271 2447 O ATOM 1036 N1 DG D 1 -23.652 -22.270 1.777 1.00 64.75 N ANISOU 1036 N1 DG D 1 10364 8927 5311 1074 -420 1932 N ATOM 1037 C2 DG D 1 -24.387 -23.419 1.607 1.00 65.08 C ANISOU 1037 C2 DG D 1 10039 9369 5320 953 -662 1715 C ATOM 1038 N2 DG D 1 -23.722 -24.581 1.648 1.00 62.73 N ANISOU 1038 N2 DG D 1 9642 9073 5122 582 -477 1374 N ATOM 1039 N3 DG D 1 -25.699 -23.424 1.409 1.00 68.38 N ANISOU 1039 N3 DG D 1 10197 10163 5623 1179 -1059 1823 N ATOM 1040 C4 DG D 1 -26.234 -22.175 1.395 1.00 70.90 C ANISOU 1040 C4 DG D 1 10657 10416 5867 1620 -1195 2191 C ATOM 1041 P DT D 2 -31.815 -25.352 1.614 1.00 82.67 P ANISOU 1041 P DT D 2 9627 14283 7502 1540 -2784 1708 P ATOM 1042 OP1 DT D 2 -32.434 -26.482 0.895 1.00 85.85 O ANISOU 1042 OP1 DT D 2 9750 15197 7672 1102 -3096 1442 O ATOM 1043 OP2 DT D 2 -32.637 -24.450 2.436 1.00 84.04 O ANISOU 1043 OP2 DT D 2 9460 14518 7953 2086 -2844 1973 O ATOM 1044 O5' DT D 2 -30.639 -25.898 2.541 1.00 76.67 O ANISOU 1044 O5' DT D 2 9063 12962 7107 1237 -2274 1453 O ATOM 1045 C5' DT D 2 -29.647 -26.761 1.997 1.00 76.18 C ANISOU 1045 C5' DT D 2 9338 12715 6894 771 -2084 1179 C ATOM 1046 C4' DT D 2 -28.593 -27.143 3.028 1.00 71.58 C ANISOU 1046 C4' DT D 2 8861 11629 6708 613 -1629 1005 C ATOM 1047 O4' DT D 2 -27.633 -26.071 3.222 1.00 69.86 O ANISOU 1047 O4' DT D 2 9040 10981 6521 854 -1368 1212 O ATOM 1048 C3' DT D 2 -29.080 -27.472 4.434 1.00 69.59 C ANISOU 1048 C3' DT D 2 8173 11341 6928 654 -1531 935 C ATOM 1049 O3' DT D 2 -28.245 -28.499 4.907 1.00 67.55 O ANISOU 1049 O3' DT D 2 7991 10797 6877 299 -1238 658 O ATOM 1050 C2' DT D 2 -28.854 -26.174 5.206 1.00 67.19 C ANISOU 1050 C2' DT D 2 7983 10743 6805 1102 -1377 1207 C ATOM 1051 C1' DT D 2 -27.515 -25.771 4.603 1.00 65.45 C ANISOU 1051 C1' DT D 2 8318 10153 6396 1020 -1155 1237 C ATOM 1052 N1 DT D 2 -27.078 -24.335 4.723 1.00 64.97 N ANISOU 1052 N1 DT D 2 8600 9773 6314 1374 -1035 1527 N ATOM 1053 C2 DT D 2 -25.721 -24.085 4.826 1.00 61.95 C ANISOU 1053 C2 DT D 2 8593 8971 5976 1223 -701 1487 C ATOM 1054 O2 DT D 2 -24.881 -24.968 4.844 1.00 59.56 O ANISOU 1054 O2 DT D 2 8318 8573 5741 882 -507 1243 O ATOM 1055 N3 DT D 2 -25.374 -22.758 4.917 1.00 62.35 N ANISOU 1055 N3 DT D 2 8981 8710 6000 1488 -589 1741 N ATOM 1056 C4 DT D 2 -26.239 -21.673 4.908 1.00 65.49 C ANISOU 1056 C4 DT D 2 9421 9127 6334 1940 -765 2039 C ATOM 1057 O4 DT D 2 -25.825 -20.519 4.996 1.00 66.37 O ANISOU 1057 O4 DT D 2 9916 8870 6433 2141 -617 2246 O ATOM 1058 C5 DT D 2 -27.647 -21.994 4.792 1.00 68.18 C ANISOU 1058 C5 DT D 2 9324 9944 6639 2154 -1121 2084 C ATOM 1059 C7 DT D 2 -28.678 -20.899 4.774 1.00 72.14 C ANISOU 1059 C7 DT D 2 9785 10534 7092 2721 -1333 2413 C ATOM 1060 C6 DT D 2 -27.994 -23.291 4.701 1.00 67.82 C ANISOU 1060 C6 DT D 2 8906 10249 6613 1834 -1243 1824 C ATOM 1061 P DG D 3 -28.837 -29.952 5.218 1.00 69.66 P ANISOU 1061 P DG D 3 7922 11242 7306 -100 -1277 362 P ATOM 1062 OP1 DG D 3 -29.634 -30.424 4.064 1.00 73.72 O ANISOU 1062 OP1 DG D 3 8336 12200 7473 -330 -1623 253 O ATOM 1063 OP2 DG D 3 -29.447 -29.848 6.567 1.00 68.72 O ANISOU 1063 OP2 DG D 3 7421 11128 7563 59 -1206 438 O ATOM 1064 O5' DG D 3 -27.518 -30.858 5.342 1.00 66.07 O ANISOU 1064 O5' DG D 3 7789 10353 6960 -393 -922 117 O ATOM 1065 C5' DG D 3 -26.339 -30.495 4.633 1.00 65.41 C ANISOU 1065 C5' DG D 3 8146 10032 6676 -372 -752 126 C ATOM 1066 C4' DG D 3 -25.084 -30.612 5.486 1.00 61.22 C ANISOU 1066 C4' DG D 3 7759 9058 6444 -352 -375 83 C ATOM 1067 O4' DG D 3 -24.705 -29.338 6.075 1.00 59.35 O ANISOU 1067 O4' DG D 3 7586 8657 6308 -30 -291 338 O ATOM 1068 C3' DG D 3 -25.116 -31.603 6.634 1.00 58.71 C ANISOU 1068 C3' DG D 3 7222 8585 6500 -482 -233 -60 C ATOM 1069 O3' DG D 3 -23.821 -32.184 6.636 1.00 57.93 O ANISOU 1069 O3' DG D 3 7362 8162 6489 -588 63 -210 O ATOM 1070 C2' DG D 3 -25.430 -30.726 7.850 1.00 56.31 C ANISOU 1070 C2' DG D 3 6714 8245 6438 -182 -224 163 C ATOM 1071 C1' DG D 3 -24.852 -29.359 7.490 1.00 55.96 C ANISOU 1071 C1' DG D 3 6918 8102 6240 78 -199 370 C ATOM 1072 N9 DG D 3 -25.666 -28.170 7.781 1.00 55.78 N ANISOU 1072 N9 DG D 3 6787 8206 6202 414 -357 619 N ATOM 1073 C8 DG D 3 -27.031 -28.069 7.958 1.00 57.87 C ANISOU 1073 C8 DG D 3 6709 8798 6481 551 -592 700 C ATOM 1074 N7 DG D 3 -27.446 -26.842 8.166 1.00 58.31 N ANISOU 1074 N7 DG D 3 6768 8864 6521 931 -660 938 N ATOM 1075 C5 DG D 3 -26.288 -26.074 8.107 1.00 55.78 C ANISOU 1075 C5 DG D 3 6855 8177 6161 999 -462 1015 C ATOM 1076 C6 DG D 3 -26.096 -24.671 8.246 1.00 55.58 C ANISOU 1076 C6 DG D 3 7083 7931 6106 1323 -406 1243 C ATOM 1077 O6 DG D 3 -26.940 -23.786 8.462 1.00 57.21 O ANISOU 1077 O6 DG D 3 7215 8204 6316 1693 -520 1436 O ATOM 1078 N1 DG D 3 -24.749 -24.320 8.122 1.00 53.32 N ANISOU 1078 N1 DG D 3 7172 7296 5793 1186 -170 1225 N ATOM 1079 C2 DG D 3 -23.727 -25.209 7.886 1.00 51.69 C ANISOU 1079 C2 DG D 3 7035 7008 5598 842 -9 1023 C ATOM 1080 N2 DG D 3 -22.501 -24.703 7.788 1.00 50.55 N ANISOU 1080 N2 DG D 3 7189 6579 5440 747 218 1035 N ATOM 1081 N3 DG D 3 -23.890 -26.517 7.749 1.00 51.90 N ANISOU 1081 N3 DG D 3 6853 7210 5656 604 -49 816 N ATOM 1082 C4 DG D 3 -25.190 -26.881 7.870 1.00 54.13 C ANISOU 1082 C4 DG D 3 6816 7795 5955 673 -279 821 C ATOM 1083 P DT D 4 -23.123 -32.874 7.906 1.00 55.62 P ANISOU 1083 P DT D 4 6999 7551 6583 -586 315 -269 P ATOM 1084 OP1 DT D 4 -22.234 -33.943 7.403 1.00 55.03 O ANISOU 1084 OP1 DT D 4 7134 7266 6508 -767 527 -507 O ATOM 1085 OP2 DT D 4 -24.165 -33.172 8.920 1.00 55.32 O ANISOU 1085 OP2 DT D 4 6660 7608 6749 -594 214 -218 O ATOM 1086 O5' DT D 4 -22.205 -31.698 8.475 1.00 53.02 O ANISOU 1086 O5' DT D 4 6737 7066 6341 -325 443 -74 O ATOM 1087 C5' DT D 4 -21.451 -30.897 7.577 1.00 54.04 C ANISOU 1087 C5' DT D 4 7110 7173 6250 -281 510 -21 C ATOM 1088 C4' DT D 4 -20.313 -30.182 8.286 1.00 51.52 C ANISOU 1088 C4' DT D 4 6838 6637 6100 -158 708 75 C ATOM 1089 O4' DT D 4 -20.748 -28.932 8.896 1.00 51.11 O ANISOU 1089 O4' DT D 4 6757 6590 6072 45 606 291 O ATOM 1090 C3' DT D 4 -19.631 -30.928 9.414 1.00 48.97 C ANISOU 1090 C3' DT D 4 6375 6134 6098 -157 861 -5 C ATOM 1091 O3' DT D 4 -18.339 -30.382 9.365 1.00 48.93 O ANISOU 1091 O3' DT D 4 6461 6009 6120 -139 1049 13 O ATOM 1092 C2' DT D 4 -20.437 -30.498 10.646 1.00 47.71 C ANISOU 1092 C2' DT D 4 6033 6003 6092 -15 735 133 C ATOM 1093 C1' DT D 4 -20.805 -29.045 10.319 1.00 48.20 C ANISOU 1093 C1' DT D 4 6199 6132 5984 131 633 310 C ATOM 1094 N1 DT D 4 -22.167 -28.493 10.695 1.00 47.28 N ANISOU 1094 N1 DT D 4 5942 6174 5847 303 439 443 N ATOM 1095 C2 DT D 4 -22.294 -27.119 10.867 1.00 47.59 C ANISOU 1095 C2 DT D 4 6097 6153 5831 519 412 618 C ATOM 1096 O2 DT D 4 -21.366 -26.321 10.782 1.00 47.44 O ANISOU 1096 O2 DT D 4 6302 5941 5781 524 536 667 O ATOM 1097 N3 DT D 4 -23.569 -26.694 11.160 1.00 47.66 N ANISOU 1097 N3 DT D 4 5946 6328 5836 729 254 729 N ATOM 1098 C4 DT D 4 -24.714 -27.465 11.286 1.00 49.12 C ANISOU 1098 C4 DT D 4 5823 6777 6064 703 116 686 C ATOM 1099 O4 DT D 4 -25.814 -26.972 11.559 1.00 50.87 O ANISOU 1099 O4 DT D 4 5854 7180 6295 922 -5 796 O ATOM 1100 C5 DT D 4 -24.523 -28.882 11.088 1.00 48.56 C ANISOU 1100 C5 DT D 4 5666 6744 6040 401 147 496 C ATOM 1101 C7 DT D 4 -25.695 -29.813 11.207 1.00 49.29 C ANISOU 1101 C7 DT D 4 5448 7094 6187 267 25 420 C ATOM 1102 C6 DT D 4 -23.276 -29.320 10.799 1.00 48.11 C ANISOU 1102 C6 DT D 4 5813 6480 5988 242 307 386 C ATOM 1103 P DC D 5 -17.108 -30.836 10.277 1.00 47.87 P ANISOU 1103 P DC D 5 6200 5726 6263 -110 1231 -44 P ATOM 1104 OP1 DC D 5 -15.891 -30.834 9.431 1.00 48.78 O ANISOU 1104 OP1 DC D 5 6402 5817 6317 -187 1456 -134 O ATOM 1105 OP2 DC D 5 -17.467 -32.077 11.008 1.00 47.08 O ANISOU 1105 OP2 DC D 5 5972 5564 6352 -93 1207 -116 O ATOM 1106 O5' DC D 5 -17.050 -29.596 11.274 1.00 44.94 O ANISOU 1106 O5' DC D 5 5786 5326 5963 -11 1164 122 O ATOM 1107 C5' DC D 5 -16.459 -28.388 10.884 1.00 45.87 C ANISOU 1107 C5' DC D 5 6046 5411 5971 -48 1235 200 C ATOM 1108 C4' DC D 5 -16.486 -27.448 12.071 1.00 45.79 C ANISOU 1108 C4' DC D 5 6008 5325 6066 31 1172 301 C ATOM 1109 O4' DC D 5 -17.864 -27.242 12.501 1.00 45.49 O ANISOU 1109 O4' DC D 5 5961 5327 5996 182 997 389 O ATOM 1110 C3' DC D 5 -15.756 -27.934 13.321 1.00 44.54 C ANISOU 1110 C3' DC D 5 5643 5145 6137 43 1196 246 C ATOM 1111 O3' DC D 5 -15.294 -26.792 13.988 1.00 44.82 O ANISOU 1111 O3' DC D 5 5735 5108 6187 9 1200 294 O ATOM 1112 C2' DC D 5 -16.876 -28.592 14.128 1.00 42.35 C ANISOU 1112 C2' DC D 5 5266 4901 5924 166 1060 272 C ATOM 1113 C1' DC D 5 -17.988 -27.578 13.872 1.00 42.34 C ANISOU 1113 C1' DC D 5 5399 4915 5773 252 959 378 C ATOM 1114 N1 DC D 5 -19.377 -28.043 14.047 1.00 41.50 N ANISOU 1114 N1 DC D 5 5191 4921 5657 347 836 410 N ATOM 1115 C2 DC D 5 -20.400 -27.095 14.171 1.00 42.19 C ANISOU 1115 C2 DC D 5 5319 5048 5663 509 743 521 C ATOM 1116 O2 DC D 5 -20.119 -25.885 14.146 1.00 42.72 O ANISOU 1116 O2 DC D 5 5573 4993 5664 578 772 592 O ATOM 1117 N3 DC D 5 -21.677 -27.538 14.323 1.00 41.98 N ANISOU 1117 N3 DC D 5 5118 5187 5645 585 639 545 N ATOM 1118 C4 DC D 5 -21.945 -28.845 14.347 1.00 42.65 C ANISOU 1118 C4 DC D 5 5044 5357 5804 451 631 458 C ATOM 1119 N4 DC D 5 -23.213 -29.225 14.495 1.00 43.55 N ANISOU 1119 N4 DC D 5 4961 5657 5930 471 541 477 N ATOM 1120 C5 DC D 5 -20.921 -29.832 14.222 1.00 41.70 C ANISOU 1120 C5 DC D 5 4955 5126 5761 292 733 347 C ATOM 1121 C6 DC D 5 -19.668 -29.380 14.071 1.00 41.73 C ANISOU 1121 C6 DC D 5 5084 5007 5765 276 830 331 C ATOM 1122 P DA D 6 -13.804 -26.259 13.824 1.00 47.42 P ANISOU 1122 P DA D 6 6038 5421 6557 -184 1351 241 P ATOM 1123 OP1 DA D 6 -13.354 -26.286 12.405 1.00 49.00 O ANISOU 1123 OP1 DA D 6 6333 5643 6640 -301 1519 219 O ATOM 1124 OP2 DA D 6 -13.006 -26.944 14.852 1.00 47.43 O ANISOU 1124 OP2 DA D 6 5765 5509 6748 -169 1323 175 O ATOM 1125 O5' DA D 6 -14.022 -24.746 14.292 1.00 48.26 O ANISOU 1125 O5' DA D 6 6373 5376 6587 -229 1317 314 O ATOM 1126 C5' DA D 6 -14.746 -23.844 13.450 1.00 49.26 C ANISOU 1126 C5' DA D 6 6808 5377 6532 -191 1331 429 C ATOM 1127 C4' DA D 6 -15.214 -22.620 14.217 1.00 49.22 C ANISOU 1127 C4' DA D 6 7026 5177 6500 -125 1283 489 C ATOM 1128 O4' DA D 6 -16.454 -22.870 14.936 1.00 47.58 O ANISOU 1128 O4' DA D 6 6758 5010 6309 140 1139 522 O ATOM 1129 C3' DA D 6 -14.264 -22.102 15.277 1.00 49.58 C ANISOU 1129 C3' DA D 6 7037 5154 6646 -314 1316 384 C ATOM 1130 O3' DA D 6 -14.454 -20.697 15.233 1.00 51.32 O ANISOU 1130 O3' DA D 6 7634 5094 6770 -352 1378 443 O ATOM 1131 C2' DA D 6 -14.754 -22.809 16.563 1.00 47.71 C ANISOU 1131 C2' DA D 6 6591 5036 6500 -145 1170 331 C ATOM 1132 C1' DA D 6 -16.263 -22.958 16.340 1.00 45.94 C ANISOU 1132 C1' DA D 6 6434 4813 6208 141 1096 436 C ATOM 1133 N9 DA D 6 -16.903 -24.234 16.691 1.00 42.26 N ANISOU 1133 N9 DA D 6 5710 4537 5812 276 1007 429 N ATOM 1134 C8 DA D 6 -16.329 -25.461 16.727 1.00 40.67 C ANISOU 1134 C8 DA D 6 5272 4471 5711 208 1005 371 C ATOM 1135 N7 DA D 6 -17.167 -26.418 17.037 1.00 39.29 N ANISOU 1135 N7 DA D 6 4962 4390 5575 328 942 390 N ATOM 1136 C5 DA D 6 -18.375 -25.788 17.203 1.00 38.83 C ANISOU 1136 C5 DA D 6 4995 4317 5443 482 897 459 C ATOM 1137 C6 DA D 6 -19.660 -26.268 17.537 1.00 39.59 C ANISOU 1137 C6 DA D 6 4974 4523 5547 625 843 503 C ATOM 1138 N6 DA D 6 -19.919 -27.561 17.773 1.00 39.67 N ANISOU 1138 N6 DA D 6 4801 4636 5637 584 830 484 N ATOM 1139 N1 DA D 6 -20.671 -25.376 17.636 1.00 40.84 N ANISOU 1139 N1 DA D 6 5207 4673 5638 811 824 570 N ATOM 1140 C2 DA D 6 -20.395 -24.086 17.406 1.00 41.96 C ANISOU 1140 C2 DA D 6 5598 4640 5704 861 858 599 C ATOM 1141 N3 DA D 6 -19.227 -23.528 17.077 1.00 42.01 N ANISOU 1141 N3 DA D 6 5783 4489 5688 689 918 564 N ATOM 1142 C4 DA D 6 -18.239 -24.441 16.993 1.00 40.55 C ANISOU 1142 C4 DA D 6 5450 4383 5576 492 933 488 C ATOM 1143 P DC D 7 -13.986 -19.705 16.400 1.00 52.63 P ANISOU 1143 P DC D 7 7955 5071 6969 -515 1392 332 P ATOM 1144 OP1 DC D 7 -13.820 -18.355 15.814 1.00 54.81 O ANISOU 1144 OP1 DC D 7 8670 5008 7150 -662 1542 400 O ATOM 1145 OP2 DC D 7 -12.835 -20.337 17.096 1.00 52.09 O ANISOU 1145 OP2 DC D 7 7539 5234 7021 -748 1352 180 O ATOM 1146 O5' DC D 7 -15.271 -19.716 17.353 1.00 50.66 O ANISOU 1146 O5' DC D 7 7749 4794 6704 -168 1273 346 O ATOM 1147 C5' DC D 7 -16.484 -19.139 16.917 1.00 50.52 C ANISOU 1147 C5' DC D 7 7980 4614 6600 138 1278 489 C ATOM 1148 C4' DC D 7 -17.486 -19.148 18.051 1.00 48.99 C ANISOU 1148 C4' DC D 7 7754 4439 6420 419 1214 452 C ATOM 1149 O4' DC D 7 -17.773 -20.518 18.393 1.00 46.18 O ANISOU 1149 O4' DC D 7 7000 4413 6133 487 1109 433 O ATOM 1150 C3' DC D 7 -17.019 -18.487 19.334 1.00 49.54 C ANISOU 1150 C3' DC D 7 7984 4355 6482 282 1252 279 C ATOM 1151 O3' DC D 7 -18.013 -17.567 19.690 1.00 51.43 O ANISOU 1151 O3' DC D 7 8525 4352 6666 576 1319 305 O ATOM 1152 C2' DC D 7 -16.890 -19.616 20.355 1.00 46.93 C ANISOU 1152 C2' DC D 7 7297 4338 6198 263 1142 186 C ATOM 1153 C1' DC D 7 -17.835 -20.662 19.789 1.00 44.57 C ANISOU 1153 C1' DC D 7 6731 4262 5943 509 1083 322 C ATOM 1154 N1 DC D 7 -17.525 -22.101 19.990 1.00 41.45 N ANISOU 1154 N1 DC D 7 5972 4153 5626 442 998 310 N ATOM 1155 C2 DC D 7 -18.585 -22.950 20.311 1.00 39.93 C ANISOU 1155 C2 DC D 7 5590 4128 5455 648 960 368 C ATOM 1156 O2 DC D 7 -19.707 -22.481 20.447 1.00 41.43 O ANISOU 1156 O2 DC D 7 5854 4283 5605 880 991 416 O ATOM 1157 N3 DC D 7 -18.353 -24.268 20.480 1.00 38.97 N ANISOU 1157 N3 DC D 7 5208 4194 5407 591 906 373 N ATOM 1158 C4 DC D 7 -17.124 -24.756 20.322 1.00 38.39 C ANISOU 1158 C4 DC D 7 5030 4164 5393 403 882 328 C ATOM 1159 N4 DC D 7 -16.977 -26.060 20.499 1.00 37.34 N ANISOU 1159 N4 DC D 7 4682 4167 5340 410 844 351 N ATOM 1160 C5 DC D 7 -16.016 -23.922 19.983 1.00 39.74 C ANISOU 1160 C5 DC D 7 5312 4235 5553 202 915 262 C ATOM 1161 C6 DC D 7 -16.263 -22.608 19.826 1.00 41.17 C ANISOU 1161 C6 DC D 7 5783 4209 5652 196 976 254 C HETATM 1162 N1 5CM D 8 -18.659 -20.470 24.165 1.00 45.68 N ANISOU 1162 N1 5CM D 8 6995 4509 5853 696 1104 -2 N HETATM 1163 C2 5CM D 8 -19.261 -21.724 24.226 1.00 43.53 C ANISOU 1163 C2 5CM D 8 6403 4502 5636 820 1064 112 C HETATM 1164 N3 5CM D 8 -18.571 -22.864 24.039 1.00 41.17 N ANISOU 1164 N3 5CM D 8 5843 4386 5411 671 954 162 N HETATM 1165 C4 5CM D 8 -17.258 -22.812 23.773 1.00 40.83 C ANISOU 1165 C4 5CM D 8 5780 4334 5401 423 876 105 C HETATM 1166 C5 5CM D 8 -16.600 -21.489 23.699 1.00 42.10 C ANISOU 1166 C5 5CM D 8 6217 4275 5506 243 913 -19 C HETATM 1167 C5A 5CM D 8 -15.139 -21.366 23.403 1.00 43.05 C ANISOU 1167 C5A 5CM D 8 6261 4426 5672 -86 849 -94 C HETATM 1168 C6 5CM D 8 -17.358 -20.350 23.896 1.00 45.21 C ANISOU 1168 C6 5CM D 8 6940 4422 5815 380 1030 -67 C HETATM 1169 O2 5CM D 8 -20.471 -21.748 24.472 1.00 45.58 O ANISOU 1169 O2 5CM D 8 6629 4809 5881 1076 1152 162 O HETATM 1170 N4 5CM D 8 -16.568 -23.962 23.578 1.00 39.89 N ANISOU 1170 N4 5CM D 8 5390 4393 5375 340 788 158 N HETATM 1171 C1' 5CM D 8 -19.539 -19.327 24.372 1.00 48.15 C ANISOU 1171 C1' 5CM D 8 7621 4574 6100 933 1253 -42 C HETATM 1172 C2' 5CM D 8 -18.901 -18.110 25.015 1.00 51.25 C ANISOU 1172 C2' 5CM D 8 8428 4672 6373 758 1318 -243 C HETATM 1173 C3' 5CM D 8 -19.805 -17.002 24.520 1.00 53.73 C ANISOU 1173 C3' 5CM D 8 9060 4653 6703 1068 1484 -197 C HETATM 1174 C4' 5CM D 8 -20.365 -17.513 23.208 1.00 51.97 C ANISOU 1174 C4' 5CM D 8 8584 4552 6610 1256 1431 45 C HETATM 1175 O4' 5CM D 8 -19.999 -18.881 23.100 1.00 49.15 O ANISOU 1175 O4' 5CM D 8 7811 4554 6311 1092 1289 97 O HETATM 1176 O3' 5CM D 8 -20.946 -16.927 25.364 1.00 55.71 O ANISOU 1176 O3' 5CM D 8 9329 4951 6890 1416 1610 -231 O HETATM 1177 C5' 5CM D 8 -19.860 -16.746 22.008 1.00 53.51 C ANISOU 1177 C5' 5CM D 8 9030 4464 6837 1153 1448 133 C HETATM 1178 O5' 5CM D 8 -18.448 -16.871 21.961 1.00 53.42 O ANISOU 1178 O5' 5CM D 8 9012 4459 6827 688 1391 32 O HETATM 1179 P 5CM D 8 -17.679 -16.368 20.663 1.00 54.26 P ANISOU 1179 P 5CM D 8 9288 4367 6962 457 1427 128 P HETATM 1180 OP1 5CM D 8 -18.381 -15.155 20.136 1.00 57.79 O ANISOU 1180 OP1 5CM D 8 10186 4403 7367 721 1560 241 O HETATM 1181 OP2 5CM D 8 -16.208 -16.297 20.972 1.00 55.07 O ANISOU 1181 OP2 5CM D 8 9376 4481 7068 -48 1409 -41 O ATOM 1182 P DG D 9 -21.112 -15.975 26.618 1.00 59.83 P ANISOU 1182 P DG D 9 10263 5233 7237 1478 1783 -474 P ATOM 1183 OP1 DG D 9 -21.563 -14.652 26.151 1.00 63.01 O ANISOU 1183 OP1 DG D 9 11094 5176 7671 1732 1959 -478 O ATOM 1184 OP2 DG D 9 -19.914 -16.082 27.464 1.00 61.07 O ANISOU 1184 OP2 DG D 9 10508 5448 7247 1032 1671 -677 O ATOM 1185 O5' DG D 9 -22.279 -16.710 27.425 1.00 59.55 O ANISOU 1185 O5' DG D 9 9947 5523 7155 1796 1877 -439 O ATOM 1186 C5' DG D 9 -23.465 -17.152 26.774 1.00 58.67 C ANISOU 1186 C5' DG D 9 9500 5601 7191 2162 1916 -228 C ATOM 1187 C4' DG D 9 -24.183 -18.213 27.590 1.00 57.61 C ANISOU 1187 C4' DG D 9 9009 5868 7013 2239 1966 -198 C ATOM 1188 O4' DG D 9 -23.531 -19.498 27.443 1.00 54.77 O ANISOU 1188 O4' DG D 9 8340 5781 6688 1923 1764 -105 O ATOM 1189 C3' DG D 9 -24.254 -17.979 29.085 1.00 59.97 C ANISOU 1189 C3' DG D 9 9536 6172 7079 2236 2137 -403 C ATOM 1190 O3' DG D 9 -25.494 -18.484 29.510 1.00 61.42 O ANISOU 1190 O3' DG D 9 9429 6635 7273 2520 2315 -329 O ATOM 1191 C2' DG D 9 -23.069 -18.767 29.639 1.00 57.78 C ANISOU 1191 C2' DG D 9 9227 6053 6674 1799 1934 -450 C ATOM 1192 C1' DG D 9 -22.924 -19.918 28.651 1.00 54.20 C ANISOU 1192 C1' DG D 9 8345 5822 6425 1696 1744 -221 C ATOM 1193 N9 DG D 9 -21.536 -20.267 28.345 1.00 51.80 N ANISOU 1193 N9 DG D 9 8032 5512 6137 1334 1511 -228 N ATOM 1194 C8 DG D 9 -20.508 -19.378 28.125 1.00 52.48 C ANISOU 1194 C8 DG D 9 8396 5348 6195 1113 1440 -363 C ATOM 1195 N7 DG D 9 -19.365 -19.944 27.871 1.00 50.64 N ANISOU 1195 N7 DG D 9 8011 5227 6003 813 1242 -341 N ATOM 1196 C5 DG D 9 -19.651 -21.295 27.909 1.00 48.21 C ANISOU 1196 C5 DG D 9 7351 5211 5754 871 1178 -176 C ATOM 1197 C6 DG D 9 -18.791 -22.389 27.699 1.00 46.20 C ANISOU 1197 C6 DG D 9 6828 5150 5575 693 1000 -81 C ATOM 1198 O6 DG D 9 -17.589 -22.377 27.438 1.00 46.12 O ANISOU 1198 O6 DG D 9 6774 5148 5600 458 857 -125 O ATOM 1199 N1 DG D 9 -19.449 -23.599 27.828 1.00 45.13 N ANISOU 1199 N1 DG D 9 6449 5210 5486 813 1017 77 N ATOM 1200 C2 DG D 9 -20.779 -23.737 28.125 1.00 45.45 C ANISOU 1200 C2 DG D 9 6456 5308 5505 1031 1187 133 C ATOM 1201 N2 DG D 9 -21.200 -25.003 28.204 1.00 44.46 N ANISOU 1201 N2 DG D 9 6095 5361 5437 1044 1192 284 N ATOM 1202 N3 DG D 9 -21.612 -22.717 28.323 1.00 47.46 N ANISOU 1202 N3 DG D 9 6890 5445 5697 1222 1357 45 N ATOM 1203 C4 DG D 9 -20.980 -21.521 28.199 1.00 48.72 C ANISOU 1203 C4 DG D 9 7343 5359 5808 1152 1342 -107 C HETATM 1204 N1 5CM D 10 -21.166 -22.141 31.793 1.00 55.53 N ANISOU 1204 N1 5CM D 10 8497 6599 6003 1093 1468 -273 N HETATM 1205 C2 5CM D 10 -20.180 -23.106 31.471 1.00 52.67 C ANISOU 1205 C2 5CM D 10 7915 6368 5730 896 1216 -142 C HETATM 1206 N3 5CM D 10 -18.909 -22.756 31.186 1.00 52.39 N ANISOU 1206 N3 5CM D 10 7918 6273 5714 666 1004 -231 N HETATM 1207 C4 5CM D 10 -18.550 -21.461 31.197 1.00 54.33 C ANISOU 1207 C4 5CM D 10 8453 6302 5888 561 1026 -454 C HETATM 1208 C5 5CM D 10 -19.562 -20.434 31.527 1.00 56.94 C ANISOU 1208 C5 5CM D 10 9092 6421 6119 765 1289 -595 C HETATM 1209 C5A 5CM D 10 -19.179 -18.981 31.549 1.00 59.86 C ANISOU 1209 C5A 5CM D 10 9870 6460 6413 649 1346 -851 C HETATM 1210 C6 5CM D 10 -20.861 -20.835 31.816 1.00 57.24 C ANISOU 1210 C6 5CM D 10 9039 6560 6148 1059 1505 -493 C HETATM 1211 O2 5CM D 10 -20.485 -24.311 31.455 1.00 51.08 O ANISOU 1211 O2 5CM D 10 7476 6334 5598 934 1208 57 O HETATM 1212 N4 5CM D 10 -17.280 -21.099 30.916 1.00 55.27 N ANISOU 1212 N4 5CM D 10 8581 6386 6034 272 832 -552 N HETATM 1213 C1' 5CM D 10 -22.527 -22.604 32.087 1.00 56.33 C ANISOU 1213 C1' 5CM D 10 8457 6839 6108 1333 1711 -167 C HETATM 1214 C2' 5CM D 10 -23.048 -22.136 33.430 1.00 60.05 C ANISOU 1214 C2' 5CM D 10 9203 7357 6257 1427 1933 -313 C HETATM 1215 C3' 5CM D 10 -24.551 -22.083 33.221 1.00 61.40 C ANISOU 1215 C3' 5CM D 10 9187 7586 6558 1740 2238 -251 C HETATM 1216 C4' 5CM D 10 -24.757 -22.178 31.720 1.00 58.75 C ANISOU 1216 C4' 5CM D 10 8557 7181 6585 1814 2131 -120 C HETATM 1217 O4' 5CM D 10 -23.463 -22.104 31.141 1.00 56.58 O ANISOU 1217 O4' 5CM D 10 8370 6761 6368 1575 1851 -139 O HETATM 1218 O3' 5CM D 10 -25.187 -23.203 33.846 1.00 62.77 O ANISOU 1218 O3' 5CM D 10 9153 8045 6652 1723 2365 -88 O HETATM 1219 C5' 5CM D 10 -25.639 -21.076 31.151 1.00 60.36 C ANISOU 1219 C5' 5CM D 10 8796 7220 6920 2152 2308 -187 C HETATM 1220 O5' 5CM D 10 -25.176 -19.800 31.592 1.00 62.97 O ANISOU 1220 O5' 5CM D 10 9594 7244 7089 2189 2372 -419 O HETATM 1221 P 5CM D 10 -25.865 -18.461 31.042 1.00 64.97 P ANISOU 1221 P 5CM D 10 10034 7192 7459 2571 2553 -498 P HETATM 1222 OP1 5CM D 10 -27.351 -18.671 31.100 1.00 67.56 O ANISOU 1222 OP1 5CM D 10 10025 7761 7883 2957 2801 -400 O HETATM 1223 OP2 5CM D 10 -25.223 -17.272 31.700 1.00 67.67 O ANISOU 1223 OP2 5CM D 10 10952 7169 7592 2506 2633 -776 O ATOM 1224 P DG D 11 -25.195 -23.373 35.442 1.00 67.68 P ANISOU 1224 P DG D 11 10047 8821 6845 1659 2517 -151 P ATOM 1225 OP1 DG D 11 -26.467 -24.020 35.834 1.00 68.92 O ANISOU 1225 OP1 DG D 11 9973 9213 6999 1778 2840 -20 O ATOM 1226 OP2 DG D 11 -24.797 -22.095 36.075 1.00 69.83 O ANISOU 1226 OP2 DG D 11 10764 8910 6859 1690 2564 -450 O ATOM 1227 O5' DG D 11 -23.994 -24.393 35.713 1.00 65.47 O ANISOU 1227 O5' DG D 11 9785 8635 6455 1366 2189 -1 O ATOM 1228 C5' DG D 11 -23.896 -25.617 34.996 1.00 62.34 C ANISOU 1228 C5' DG D 11 9065 8306 6315 1276 2052 255 C ATOM 1229 C4' DG D 11 -22.603 -26.306 35.377 1.00 61.47 C ANISOU 1229 C4' DG D 11 9047 8244 6066 1081 1739 355 C ATOM 1230 O4' DG D 11 -21.481 -25.606 34.791 1.00 59.66 O ANISOU 1230 O4' DG D 11 8863 7878 5927 990 1468 208 O ATOM 1231 C3' DG D 11 -22.325 -26.351 36.869 1.00 65.29 C ANISOU 1231 C3' DG D 11 9847 8883 6078 1021 1746 338 C ATOM 1232 O3' DG D 11 -21.757 -27.610 37.146 1.00 66.25 O ANISOU 1232 O3' DG D 11 9912 9113 6148 933 1565 607 O ATOM 1233 C2' DG D 11 -21.324 -25.219 37.094 1.00 65.58 C ANISOU 1233 C2' DG D 11 10134 8844 5941 924 1533 65 C ATOM 1234 C1' DG D 11 -20.535 -25.316 35.797 1.00 61.86 C ANISOU 1234 C1' DG D 11 9402 8244 5857 855 1282 104 C ATOM 1235 N9 DG D 11 -19.802 -24.118 35.398 1.00 61.20 N ANISOU 1235 N9 DG D 11 9446 7997 5811 749 1152 -153 N ATOM 1236 C8 DG D 11 -20.186 -22.800 35.509 1.00 62.90 C ANISOU 1236 C8 DG D 11 9936 8021 5943 792 1328 -422 C ATOM 1237 N7 DG D 11 -19.298 -21.963 35.052 1.00 62.44 N ANISOU 1237 N7 DG D 11 9974 7799 5952 619 1163 -600 N ATOM 1238 C5 DG D 11 -18.266 -22.782 34.613 1.00 60.09 C ANISOU 1238 C5 DG D 11 9394 7645 5794 464 863 -443 C ATOM 1239 C6 DG D 11 -17.026 -22.451 34.024 1.00 59.80 C ANISOU 1239 C6 DG D 11 9263 7572 5884 225 613 -525 C ATOM 1240 O6 DG D 11 -16.585 -21.327 33.762 1.00 60.86 O ANISOU 1240 O6 DG D 11 9585 7510 6029 52 606 -754 O ATOM 1241 N1 DG D 11 -16.269 -23.587 33.731 1.00 58.49 N ANISOU 1241 N1 DG D 11 8758 7613 5854 192 384 -309 N ATOM 1242 C2 DG D 11 -16.657 -24.880 33.982 1.00 57.14 C ANISOU 1242 C2 DG D 11 8425 7598 5688 360 392 -41 C ATOM 1243 N2 DG D 11 -15.792 -25.840 33.637 1.00 56.13 N ANISOU 1243 N2 DG D 11 8014 7602 5709 345 175 136 N ATOM 1244 N3 DG D 11 -17.816 -25.203 34.535 1.00 57.03 N ANISOU 1244 N3 DG D 11 8526 7594 5547 528 626 44 N ATOM 1245 C4 DG D 11 -18.561 -24.108 34.817 1.00 58.77 C ANISOU 1245 C4 DG D 11 9013 7676 5641 571 851 -169 C ATOM 1246 P DT D 12 -21.857 -28.238 38.607 1.00 70.62 P ANISOU 1246 P DT D 12 10732 9866 6234 903 1638 764 P ATOM 1247 OP1 DT D 12 -22.996 -29.182 38.589 1.00 70.85 O ANISOU 1247 OP1 DT D 12 10627 9918 6375 931 1957 993 O ATOM 1248 OP2 DT D 12 -21.766 -27.172 39.633 1.00 73.30 O ANISOU 1248 OP2 DT D 12 11424 10292 6135 887 1684 502 O ATOM 1249 O5' DT D 12 -20.510 -29.073 38.697 1.00 69.83 O ANISOU 1249 O5' DT D 12 10616 9824 6094 836 1224 966 O ATOM 1250 C5' DT D 12 -19.923 -29.630 37.547 1.00 66.52 C ANISOU 1250 C5' DT D 12 9902 9278 6097 841 1030 1068 C ATOM 1251 C4' DT D 12 -18.429 -29.410 37.650 1.00 67.22 C ANISOU 1251 C4' DT D 12 9982 9462 6099 786 612 1014 C ATOM 1252 O4' DT D 12 -18.138 -28.043 37.257 1.00 66.60 O ANISOU 1252 O4' DT D 12 9913 9326 6066 692 563 672 O ATOM 1253 C3' DT D 12 -17.851 -29.554 39.058 1.00 71.58 C ANISOU 1253 C3' DT D 12 10802 10263 6133 763 415 1095 C ATOM 1254 O3' DT D 12 -16.600 -30.221 39.004 1.00 73.34 O ANISOU 1254 O3' DT D 12 10871 10595 6398 800 28 1270 O ATOM 1255 C2' DT D 12 -17.651 -28.108 39.491 1.00 72.71 C ANISOU 1255 C2' DT D 12 11141 10471 6015 629 373 716 C ATOM 1256 C1' DT D 12 -17.162 -27.564 38.156 1.00 68.70 C ANISOU 1256 C1' DT D 12 10349 9787 5965 573 279 552 C ATOM 1257 N1 DT D 12 -17.009 -26.079 38.038 1.00 67.72 N ANISOU 1257 N1 DT D 12 10368 9570 5792 425 292 170 N ATOM 1258 C2 DT D 12 -15.876 -25.572 37.425 1.00 66.35 C ANISOU 1258 C2 DT D 12 10031 9390 5788 257 20 25 C ATOM 1259 O2 DT D 12 -14.974 -26.249 36.965 1.00 64.97 O ANISOU 1259 O2 DT D 12 9559 9319 5808 251 -230 181 O ATOM 1260 N3 DT D 12 -15.834 -24.208 37.367 1.00 67.08 N ANISOU 1260 N3 DT D 12 10333 9334 5822 93 83 -318 N ATOM 1261 C4 DT D 12 -16.776 -23.317 37.841 1.00 69.05 C ANISOU 1261 C4 DT D 12 10940 9425 5873 134 383 -534 C ATOM 1262 O4 DT D 12 -16.621 -22.108 37.727 1.00 70.70 O ANISOU 1262 O4 DT D 12 11367 9439 6055 -11 429 -840 O ATOM 1263 C5 DT D 12 -17.937 -23.903 38.472 1.00 69.58 C ANISOU 1263 C5 DT D 12 11114 9551 5774 354 665 -378 C ATOM 1264 C7 DT D 12 -19.027 -23.030 39.027 1.00 71.44 C ANISOU 1264 C7 DT D 12 11690 9654 5798 461 1043 -600 C ATOM 1265 C6 DT D 12 -17.996 -25.243 38.536 1.00 68.84 C ANISOU 1265 C6 DT D 12 10810 9617 5730 459 607 -34 C ATOM 1266 P DC D 13 -16.305 -31.473 39.956 1.00 77.83 P ANISOU 1266 P DC D 13 11586 11308 6676 934 -113 1668 P ATOM 1267 OP1 DC D 13 -16.562 -32.659 39.101 1.00 75.00 O ANISOU 1267 OP1 DC D 13 11051 10704 6742 1063 16 1936 O ATOM 1268 OP2 DC D 13 -17.036 -31.297 41.235 1.00 81.09 O ANISOU 1268 OP2 DC D 13 12392 11856 6560 893 71 1687 O ATOM 1269 O5' DC D 13 -14.755 -31.311 40.359 1.00 80.82 O ANISOU 1269 O5' DC D 13 11859 11982 6867 931 -638 1654 O ATOM 1270 C5' DC D 13 -13.686 -31.706 39.496 1.00 80.83 C ANISOU 1270 C5' DC D 13 11477 11986 7249 1019 -907 1720 C ATOM 1271 C4' DC D 13 -12.738 -30.556 39.183 1.00 81.53 C ANISOU 1271 C4' DC D 13 11351 12245 7382 814 -1166 1370 C ATOM 1272 O4' DC D 13 -13.488 -29.323 39.044 1.00 79.78 O ANISOU 1272 O4' DC D 13 11312 11881 7120 598 -907 1014 O ATOM 1273 C3' DC D 13 -11.728 -30.197 40.268 1.00 87.27 C ANISOU 1273 C3' DC D 13 12119 13393 7648 720 -1602 1318 C ATOM 1274 O3' DC D 13 -10.552 -31.013 40.220 1.00 90.89 O ANISOU 1274 O3' DC D 13 12242 14083 8208 909 -1984 1567 O ATOM 1275 C2' DC D 13 -11.389 -28.735 39.968 1.00 86.33 C ANISOU 1275 C2' DC D 13 11952 13302 7548 381 -1647 857 C ATOM 1276 C1' DC D 13 -12.557 -28.252 39.118 1.00 81.11 C ANISOU 1276 C1' DC D 13 11405 12226 7186 352 -1174 701 C ATOM 1277 N1 DC D 13 -13.218 -26.967 39.580 1.00 80.99 N ANISOU 1277 N1 DC D 13 11757 12119 6898 142 -973 344 N ATOM 1278 C2 DC D 13 -12.626 -25.727 39.269 1.00 81.43 C ANISOU 1278 C2 DC D 13 11797 12146 6994 -150 -1071 -27 C ATOM 1279 O2 DC D 13 -11.560 -25.679 38.639 1.00 81.59 O ANISOU 1279 O2 DC D 13 11467 12269 7264 -268 -1322 -60 O ATOM 1280 N3 DC D 13 -13.236 -24.584 39.669 1.00 81.68 N ANISOU 1280 N3 DC D 13 12217 12021 6795 -304 -859 -353 N ATOM 1281 C4 DC D 13 -14.380 -24.626 40.341 1.00 82.35 C ANISOU 1281 C4 DC D 13 12641 12026 6621 -158 -552 -329 C ATOM 1282 N4 DC D 13 -14.912 -23.452 40.697 1.00 83.90 N ANISOU 1282 N4 DC D 13 13216 12051 6611 -276 -326 -677 N ATOM 1283 C5 DC D 13 -15.004 -25.870 40.675 1.00 82.07 C ANISOU 1283 C5 DC D 13 12583 12068 6532 105 -438 48 C ATOM 1284 C6 DC D 13 -14.395 -26.999 40.277 1.00 81.09 C ANISOU 1284 C6 DC D 13 12126 12049 6636 233 -659 375 C ATOM 1285 P DT D 14 -9.538 -31.026 41.479 1.00 98.66 P ANISOU 1285 P DT D 14 13235 15587 8663 909 -2507 1653 P ATOM 1286 OP1 DT D 14 -8.650 -32.199 41.313 1.00100.73 O ANISOU 1286 OP1 DT D 14 13164 15986 9121 1267 -2787 2035 O ATOM 1287 OP2 DT D 14 -10.281 -30.836 42.755 1.00100.87 O ANISOU 1287 OP2 DT D 14 14044 15955 8327 838 -2434 1667 O ATOM 1288 O5' DT D 14 -8.688 -29.695 41.241 1.00 99.46 O ANISOU 1288 O5' DT D 14 13093 15915 8783 519 -2740 1195 O ATOM 1289 C5' DT D 14 -7.817 -29.538 40.117 1.00 97.65 C ANISOU 1289 C5' DT D 14 12346 15698 9057 463 -2829 1084 C ATOM 1290 C4' DT D 14 -7.055 -28.238 40.300 1.00 99.90 C ANISOU 1290 C4' DT D 14 12522 16254 9182 9 -3075 660 C ATOM 1291 O4' DT D 14 -7.994 -27.127 40.298 1.00 97.36 O ANISOU 1291 O4' DT D 14 12637 15609 8746 -281 -2731 314 O ATOM 1292 C3' DT D 14 -6.291 -28.162 41.617 1.00106.42 C ANISOU 1292 C3' DT D 14 13369 17627 9437 -88 -3586 666 C ATOM 1293 O3' DT D 14 -4.976 -27.679 41.374 1.00110.07 O ANISOU 1293 O3' DT D 14 13318 18482 10021 -346 -3966 471 O ATOM 1294 C2' DT D 14 -7.152 -27.246 42.495 1.00106.91 C ANISOU 1294 C2' DT D 14 14047 17584 8991 -367 -3420 378 C ATOM 1295 C1' DT D 14 -7.870 -26.362 41.482 1.00101.31 C ANISOU 1295 C1' DT D 14 13459 16367 8668 -563 -2945 71 C ATOM 1296 N1 DT D 14 -9.240 -25.873 41.915 1.00 98.90 N ANISOU 1296 N1 DT D 14 13751 15721 8106 -579 -2520 -67 N ATOM 1297 C2 DT D 14 -9.529 -24.523 41.814 1.00 98.20 C ANISOU 1297 C2 DT D 14 13940 15404 7966 -924 -2325 -516 C ATOM 1298 O2 DT D 14 -8.753 -23.681 41.393 1.00 98.99 O ANISOU 1298 O2 DT D 14 13871 15532 8206 -1269 -2470 -810 O ATOM 1299 N3 DT D 14 -10.790 -24.180 42.233 1.00 96.48 N ANISOU 1299 N3 DT D 14 14226 14904 7530 -847 -1920 -608 N ATOM 1300 C4 DT D 14 -11.787 -24.991 42.736 1.00 95.67 C ANISOU 1300 C4 DT D 14 14349 14751 7251 -530 -1677 -322 C ATOM 1301 O4 DT D 14 -12.872 -24.515 43.071 1.00 94.35 O ANISOU 1301 O4 DT D 14 14583 14358 6908 -501 -1288 -468 O ATOM 1302 C5 DT D 14 -11.429 -26.395 42.822 1.00 96.23 C ANISOU 1302 C5 DT D 14 14149 15042 7373 -240 -1893 149 C ATOM 1303 C7 DT D 14 -12.405 -27.408 43.352 1.00 96.04 C ANISOU 1303 C7 DT D 14 14362 14956 7171 63 -1641 512 C ATOM 1304 C6 DT D 14 -10.194 -26.757 42.415 1.00 97.66 C ANISOU 1304 C6 DT D 14 13864 15470 7772 -253 -2301 252 C ATOM 1305 P DA D 15 -4.089 -27.050 42.553 1.00118.69 P ANISOU 1305 P DA D 15 14380 20176 10539 -693 -4519 257 P ATOM 1306 OP1 DA D 15 -2.673 -27.050 42.126 1.00122.42 O ANISOU 1306 OP1 DA D 15 14123 21108 11283 -802 -4916 221 O ATOM 1307 OP2 DA D 15 -4.430 -27.682 43.853 1.00121.91 O ANISOU 1307 OP2 DA D 15 15171 20809 10341 -446 -4725 533 O ATOM 1308 O5' DA D 15 -4.645 -25.547 42.541 1.00117.29 O ANISOU 1308 O5' DA D 15 14650 19691 10225 -1242 -4239 -285 O ATOM 1309 C5' DA D 15 -4.293 -24.606 41.518 1.00114.04 C ANISOU 1309 C5' DA D 15 14020 19073 10236 -1627 -4072 -628 C ATOM 1310 C4' DA D 15 -4.030 -23.244 42.146 1.00117.78 C ANISOU 1310 C4' DA D 15 14786 19644 10319 -2243 -4210 -1140 C ATOM 1311 O4' DA D 15 -5.285 -22.641 42.562 1.00115.21 O ANISOU 1311 O4' DA D 15 15202 18862 9712 -2276 -3810 -1329 O ATOM 1312 C3' DA D 15 -3.137 -23.244 43.387 1.00125.40 C ANISOU 1312 C3' DA D 15 15644 21291 10709 -2451 -4827 -1206 C ATOM 1313 O3' DA D 15 -2.272 -22.107 43.339 1.00130.43 O ANISOU 1313 O3' DA D 15 16123 22118 11317 -3114 -5038 -1675 O ATOM 1314 C2' DA D 15 -4.128 -23.209 44.557 1.00125.81 C ANISOU 1314 C2' DA D 15 16429 21247 10126 -2352 -4726 -1221 C ATOM 1315 C1' DA D 15 -5.364 -22.521 43.981 1.00119.49 C ANISOU 1315 C1' DA D 15 16143 19715 9541 -2377 -4069 -1427 C ATOM 1316 N9 DA D 15 -6.666 -23.068 44.403 1.00115.00 N ANISOU 1316 N9 DA D 15 16060 18861 8773 -1959 -3701 -1192 N ATOM 1317 C8 DA D 15 -7.019 -24.387 44.545 1.00112.61 C ANISOU 1317 C8 DA D 15 15664 18636 8486 -1442 -3691 -681 C ATOM 1318 N7 DA D 15 -8.265 -24.582 44.916 1.00109.63 N ANISOU 1318 N7 DA D 15 15777 17959 7919 -1216 -3282 -584 N ATOM 1319 C5 DA D 15 -8.779 -23.300 45.023 1.00109.47 C ANISOU 1319 C5 DA D 15 16192 17647 7753 -1549 -3002 -1064 C ATOM 1320 C6 DA D 15 -10.057 -22.805 45.381 1.00107.50 C ANISOU 1320 C6 DA D 15 16523 17031 7292 -1493 -2505 -1232 C ATOM 1321 N6 DA D 15 -11.093 -23.581 45.713 1.00104.74 N ANISOU 1321 N6 DA D 15 16388 16581 6828 -1121 -2192 -923 N ATOM 1322 N1 DA D 15 -10.235 -21.466 45.388 1.00108.55 N ANISOU 1322 N1 DA D 15 17011 16893 7341 -1836 -2315 -1736 N ATOM 1323 C2 DA D 15 -9.210 -20.665 45.061 1.00111.41 C ANISOU 1323 C2 DA D 15 17189 17326 7815 -2275 -2598 -2056 C ATOM 1324 N3 DA D 15 -7.968 -21.011 44.709 1.00113.33 N ANISOU 1324 N3 DA D 15 16858 17944 8258 -2425 -3065 -1948 N ATOM 1325 C4 DA D 15 -7.811 -22.353 44.708 1.00112.60 C ANISOU 1325 C4 DA D 15 16392 18138 8253 -2012 -3251 -1441 C ATOM 1326 P DT D 16 -1.330 -21.643 44.560 1.00140.97 P ANISOU 1326 P DT D 16 17401 24137 12023 -3586 -5673 -1951 P ATOM 1327 OP1 DT D 16 -0.112 -21.048 43.963 1.00144.28 O ANISOU 1327 OP1 DT D 16 17200 24855 12764 -4108 -5913 -2215 O ATOM 1328 OP2 DT D 16 -1.196 -22.727 45.568 1.00144.18 O ANISOU 1328 OP2 DT D 16 17741 25067 11976 -3142 -6101 -1546 O ATOM 1329 O5' DT D 16 -2.189 -20.475 45.238 1.00141.97 O ANISOU 1329 O5' DT D 16 18421 23852 11668 -3988 -5396 -2431 O ATOM 1330 C5' DT D 16 -2.734 -19.399 44.459 1.00137.55 C ANISOU 1330 C5' DT D 16 18227 22606 11430 -4295 -4869 -2788 C ATOM 1331 C4' DT D 16 -3.301 -18.305 45.356 1.00140.40 C ANISOU 1331 C4' DT D 16 19407 22713 11226 -4688 -4732 -3279 C ATOM 1332 O4' DT D 16 -4.662 -18.633 45.746 1.00136.35 O ANISOU 1332 O4' DT D 16 19484 21824 10500 -4196 -4313 -3111 O ATOM 1333 C3' DT D 16 -2.547 -18.020 46.653 1.00148.60 C ANISOU 1333 C3' DT D 16 20532 24382 11545 -5130 -5317 -3560 C ATOM 1334 O3' DT D 16 -2.526 -16.598 46.848 1.00152.51 O ANISOU 1334 O3' DT D 16 21553 24556 11839 -5810 -5181 -4194 O ATOM 1335 C2' DT D 16 -3.344 -18.813 47.693 1.00148.39 C ANISOU 1335 C2' DT D 16 20919 24504 10960 -4626 -5327 -3270 C ATOM 1336 C1' DT D 16 -4.768 -18.695 47.157 1.00141.02 C ANISOU 1336 C1' DT D 16 20489 22781 10310 -4247 -4578 -3207 C ATOM 1337 N1 DT D 16 -5.699 -19.829 47.498 1.00136.64 N ANISOU 1337 N1 DT D 16 20080 22212 9627 -3572 -4383 -2710 N ATOM 1338 C2 DT D 16 -7.023 -19.543 47.804 1.00133.89 C ANISOU 1338 C2 DT D 16 20404 21383 9084 -3370 -3832 -2802 C ATOM 1339 O2 DT D 16 -7.498 -18.416 47.829 1.00134.72 O ANISOU 1339 O2 DT D 16 21021 21056 9112 -3650 -3492 -3263 O ATOM 1340 N3 DT D 16 -7.791 -20.646 48.091 1.00129.95 N ANISOU 1340 N3 DT D 16 19963 20921 8492 -2813 -3667 -2325 N ATOM 1341 C4 DT D 16 -7.394 -21.972 48.103 1.00129.37 C ANISOU 1341 C4 DT D 16 19428 21233 8493 -2431 -3979 -1773 C ATOM 1342 O4 DT D 16 -8.184 -22.869 48.378 1.00126.13 O ANISOU 1342 O4 DT D 16 19178 20760 7985 -1988 -3757 -1380 O ATOM 1343 C5 DT D 16 -6.003 -22.207 47.771 1.00132.17 C ANISOU 1343 C5 DT D 16 19109 22050 9058 -2595 -4552 -1697 C ATOM 1344 C7 DT D 16 -5.443 -23.601 47.752 1.00132.38 C ANISOU 1344 C7 DT D 16 18610 22487 9199 -2144 -4916 -1112 C ATOM 1345 C6 DT D 16 -5.236 -21.139 47.487 1.00135.46 C ANISOU 1345 C6 DT D 16 19392 22504 9573 -3157 -4723 -2166 C ATOM 1346 P DA D 17 -2.468 -15.868 48.280 1.00161.68 P ANISOU 1346 P DA D 17 23354 25955 12120 -6296 -5450 -4690 P ATOM 1347 OP1 DA D 17 -2.036 -14.471 48.041 1.00165.93 O ANISOU 1347 OP1 DA D 17 24153 26170 12722 -7090 -5364 -5315 O ATOM 1348 OP2 DA D 17 -1.700 -16.691 49.248 1.00166.92 O ANISOU 1348 OP2 DA D 17 23632 27530 12259 -6239 -6162 -4469 O ATOM 1349 O5' DA D 17 -4.010 -15.892 48.723 1.00157.40 O ANISOU 1349 O5' DA D 17 23641 24862 11303 -5804 -4868 -4644 O ATOM 1350 C5' DA D 17 -4.838 -14.729 48.696 1.00155.74 C ANISOU 1350 C5' DA D 17 24218 23913 11042 -6008 -4310 -5113 C ATOM 1351 C4' DA D 17 -5.750 -14.726 49.909 1.00157.10 C ANISOU 1351 C4' DA D 17 25139 24067 10484 -5798 -4132 -5232 C ATOM 1352 O4' DA D 17 -6.501 -15.967 49.943 1.00151.10 O ANISOU 1352 O4' DA D 17 24213 23418 9779 -5049 -3979 -4627 O ATOM 1353 C3' DA D 17 -5.033 -14.626 51.252 1.00165.74 C ANISOU 1353 C3' DA D 17 26419 25840 10717 -6240 -4725 -5512 C ATOM 1354 O3' DA D 17 -5.718 -13.692 52.072 1.00170.26 O ANISOU 1354 O3' DA D 17 27926 26048 10716 -6462 -4390 -6046 O ATOM 1355 C2' DA D 17 -5.124 -16.042 51.816 1.00164.21 C ANISOU 1355 C2' DA D 17 25920 26240 10233 -5665 -5019 -4900 C ATOM 1356 C1' DA D 17 -6.475 -16.478 51.260 1.00155.67 C ANISOU 1356 C1' DA D 17 25036 24556 9556 -4988 -4308 -4554 C ATOM 1357 N9 DA D 17 -6.708 -17.925 51.244 1.00150.79 N ANISOU 1357 N9 DA D 17 24017 24245 9033 -4352 -4395 -3858 N ATOM 1358 C8 DA D 17 -5.781 -18.909 51.020 1.00150.26 C ANISOU 1358 C8 DA D 17 23208 24727 9157 -4201 -4935 -3410 C ATOM 1359 N7 DA D 17 -6.274 -20.125 51.069 1.00146.46 N ANISOU 1359 N7 DA D 17 22593 24333 8723 -3592 -4851 -2822 N ATOM 1360 C5 DA D 17 -7.620 -19.929 51.346 1.00143.98 C ANISOU 1360 C5 DA D 17 22930 23540 8237 -3364 -4218 -2889 C ATOM 1361 C6 DA D 17 -8.696 -20.827 51.529 1.00140.20 C ANISOU 1361 C6 DA D 17 22648 22907 7714 -2809 -3817 -2449 C ATOM 1362 N6 DA D 17 -8.549 -22.152 51.448 1.00138.34 N ANISOU 1362 N6 DA D 17 22019 22936 7609 -2379 -4015 -1829 N ATOM 1363 N1 DA D 17 -9.925 -20.315 51.796 1.00139.38 N ANISOU 1363 N1 DA D 17 23158 22357 7441 -2718 -3186 -2671 N ATOM 1364 C2 DA D 17 -10.062 -18.983 51.874 1.00141.43 C ANISOU 1364 C2 DA D 17 23857 22297 7583 -3107 -2968 -3293 C ATOM 1365 N3 DA D 17 -9.123 -18.041 51.722 1.00145.14 N ANISOU 1365 N3 DA D 17 24271 22805 8071 -3657 -3294 -3753 N ATOM 1366 C4 DA D 17 -7.910 -18.579 51.459 1.00146.43 C ANISOU 1366 C4 DA D 17 23771 23463 8401 -3788 -3926 -3522 C ATOM 1367 P DC D 18 -4.917 -12.772 53.110 1.00181.36 P ANISOU 1367 P DC D 18 29752 27791 11364 -7290 -4839 -6719 P ATOM 1368 OP1 DC D 18 -5.834 -11.689 53.528 1.00184.15 O ANISOU 1368 OP1 DC D 18 31115 27450 11403 -7417 -4240 -7278 O ATOM 1369 OP2 DC D 18 -3.609 -12.411 52.519 1.00184.03 O ANISOU 1369 OP2 DC D 18 29465 28394 12064 -7922 -5319 -6886 O ATOM 1370 O5' DC D 18 -4.632 -13.769 54.338 1.00185.89 O ANISOU 1370 O5' DC D 18 30228 29271 11131 -7109 -5420 -6422 O ATOM 1371 C5' DC D 18 -5.402 -13.750 55.548 1.00189.33 C ANISOU 1371 C5' DC D 18 31460 29761 10717 -6966 -5240 -6575 C ATOM 1372 C4' DC D 18 -6.798 -14.324 55.347 1.00181.62 C ANISOU 1372 C4' DC D 18 30735 28313 9957 -6174 -4528 -6165 C ATOM 1373 O4' DC D 18 -6.750 -15.546 54.567 1.00173.72 O ANISOU 1373 O4' DC D 18 28950 27484 9571 -5612 -4619 -5422 O ATOM 1374 C3' DC D 18 -7.517 -14.699 56.635 1.00185.48 C ANISOU 1374 C3' DC D 18 31861 29062 9551 -5917 -4405 -6120 C ATOM 1375 O3' DC D 18 -8.331 -13.616 57.070 1.00188.46 O ANISOU 1375 O3' DC D 18 33141 28875 9592 -6080 -3814 -6730 O ATOM 1376 C2' DC D 18 -8.395 -15.884 56.242 1.00177.59 C ANISOU 1376 C2' DC D 18 30576 27965 8934 -5114 -4036 -5392 C ATOM 1377 C1' DC D 18 -7.906 -16.309 54.853 1.00169.74 C ANISOU 1377 C1' DC D 18 28709 26842 8942 -4961 -4158 -5013 C ATOM 1378 N1 DC D 18 -7.610 -17.786 54.762 1.00166.46 N ANISOU 1378 N1 DC D 18 27657 26932 8659 -4486 -4522 -4256 N ATOM 1379 C2 DC D 18 -8.662 -18.714 54.897 1.00162.34 C ANISOU 1379 C2 DC D 18 27272 26285 8127 -3861 -4095 -3756 C ATOM 1380 O2 DC D 18 -9.823 -18.321 55.083 1.00161.32 O ANISOU 1380 O2 DC D 18 27711 25693 7891 -3695 -3430 -3937 O ATOM 1381 N3 DC D 18 -8.384 -20.041 54.815 1.00160.62 N ANISOU 1381 N3 DC D 18 26549 26447 8031 -3446 -4403 -3079 N ATOM 1382 C4 DC D 18 -7.130 -20.461 54.613 1.00162.19 C ANISOU 1382 C4 DC D 18 26103 27157 8363 -3565 -5104 -2883 C ATOM 1383 N4 DC D 18 -6.929 -21.783 54.541 1.00160.99 N ANISOU 1383 N4 DC D 18 25520 27307 8341 -3082 -5349 -2204 N ATOM 1384 C5 DC D 18 -6.042 -19.540 54.472 1.00166.22 C ANISOU 1384 C5 DC D 18 26383 27877 8896 -4186 -5557 -3380 C ATOM 1385 C6 DC D 18 -6.326 -18.230 54.557 1.00168.18 C ANISOU 1385 C6 DC D 18 27166 27722 9012 -4658 -5246 -4054 C ATOM 1386 P DG D 19 -7.909 -12.702 58.318 1.00199.99 P ANISOU 1386 P DG D 19 35358 30587 10043 -6760 -4085 -7463 P ATOM 1387 OP1 DG D 19 -7.888 -11.305 57.830 1.00201.61 O ANISOU 1387 OP1 DG D 19 35969 30070 10565 -7244 -3750 -8152 O ATOM 1388 OP2 DG D 19 -6.689 -13.268 58.937 1.00205.88 O ANISOU 1388 OP2 DG D 19 35667 32288 10271 -7103 -5032 -7311 O ATOM 1389 O5' DG D 19 -9.126 -12.839 59.359 1.00202.31 O ANISOU 1389 O5' DG D 19 36471 30800 9599 -6356 -3523 -7501 O ATOM 1390 C5' DG D 19 -10.132 -13.859 59.243 1.00195.60 C ANISOU 1390 C5' DG D 19 35472 29902 8944 -5585 -3077 -6856 C ATOM 1391 C4' DG D 19 -9.933 -15.000 60.234 1.00198.59 C ANISOU 1391 C4' DG D 19 35794 31091 8571 -5395 -3525 -6368 C ATOM 1392 O4' DG D 19 -9.168 -16.050 59.578 1.00193.46 O ANISOU 1392 O4' DG D 19 34214 30847 8446 -5196 -4091 -5706 O ATOM 1393 C3' DG D 19 -9.181 -14.652 61.521 1.00209.64 C ANISOU 1393 C3' DG D 19 37675 33125 8855 -5961 -4117 -6791 C ATOM 1394 O3' DG D 19 -9.858 -15.179 62.661 1.00214.24 O ANISOU 1394 O3' DG D 19 38831 34024 8547 -5683 -3914 -6614 O ATOM 1395 C2' DG D 19 -7.815 -15.306 61.329 1.00210.24 C ANISOU 1395 C2' DG D 19 36924 33920 9037 -6165 -5089 -6427 C ATOM 1396 C1' DG D 19 -8.162 -16.509 60.457 1.00200.20 C ANISOU 1396 C1' DG D 19 34951 32557 8560 -5459 -4927 -5588 C ATOM 1397 N9 DG D 19 -7.046 -17.077 59.692 1.00196.77 N ANISOU 1397 N9 DG D 19 33556 32488 8719 -5485 -5591 -5205 N ATOM 1398 C8 DG D 19 -5.834 -16.488 59.410 1.00200.07 C ANISOU 1398 C8 DG D 19 33556 33178 9284 -6083 -6199 -5558 C ATOM 1399 N7 DG D 19 -5.030 -17.242 58.713 1.00196.46 N ANISOU 1399 N7 DG D 19 32195 33056 9396 -5913 -6670 -5072 N ATOM 1400 C5 DG D 19 -5.751 -18.410 58.514 1.00190.15 C ANISOU 1400 C5 DG D 19 31251 32156 8842 -5158 -6364 -4357 C ATOM 1401 C6 DG D 19 -5.386 -19.591 57.822 1.00184.77 C ANISOU 1401 C6 DG D 19 29776 31670 8760 -4659 -6604 -3638 C ATOM 1402 O6 DG D 19 -4.323 -19.830 57.235 1.00184.56 O ANISOU 1402 O6 DG D 19 28966 31980 9177 -4753 -7137 -3489 O ATOM 1403 N1 DG D 19 -6.379 -20.570 57.830 1.00179.67 N ANISOU 1403 N1 DG D 19 29287 30787 8192 -3998 -6139 -3064 N ATOM 1404 C2 DG D 19 -7.625 -20.522 58.413 1.00179.35 C ANISOU 1404 C2 DG D 19 29997 30410 7737 -3793 -5491 -3104 C ATOM 1405 N2 DG D 19 -8.189 -21.865 58.063 1.00173.59 N ANISOU 1405 N2 DG D 19 29000 29577 7380 -3117 -5249 -2323 N ATOM 1406 N3 DG D 19 -7.973 -19.259 59.132 1.00185.12 N ANISOU 1406 N3 DG D 19 31514 30977 7847 -4281 -5237 -3866 N ATOM 1407 C4 DG D 19 -6.991 -18.326 59.108 1.00190.14 C ANISOU 1407 C4 DG D 19 32039 31795 8409 -4916 -5707 -4424 C TER 1408 DG D 19 ATOM 1409 P DG E 21 -14.495 -29.071 54.949 1.00146.81 P ANISOU 1409 P DG E 21 25013 23784 6986 28 -1791 1460 P ATOM 1410 OP1 DG E 21 -13.937 -30.244 55.668 1.00152.19 O ANISOU 1410 OP1 DG E 21 25815 24795 7214 248 -2205 2077 O ATOM 1411 OP2 DG E 21 -14.758 -29.131 53.493 1.00138.54 O ANISOU 1411 OP2 DG E 21 23424 22273 6944 131 -1545 1437 O ATOM 1412 O5' DG E 21 -15.829 -28.579 55.699 1.00149.26 O ANISOU 1412 O5' DG E 21 25915 23983 6812 -69 -1072 1219 O ATOM 1413 C5' DG E 21 -15.809 -28.136 57.074 1.00156.84 C ANISOU 1413 C5' DG E 21 27505 25329 6759 -248 -1135 1026 C ATOM 1414 C4' DG E 21 -15.661 -26.621 57.187 1.00158.10 C ANISOU 1414 C4' DG E 21 27841 25492 6737 -576 -1138 257 C ATOM 1415 O4' DG E 21 -14.312 -26.335 57.652 1.00162.55 O ANISOU 1415 O4' DG E 21 28387 26518 6855 -799 -1946 119 O ATOM 1416 C3' DG E 21 -15.821 -25.830 55.883 1.00150.98 C ANISOU 1416 C3' DG E 21 26499 24127 6740 -622 -925 -133 C ATOM 1417 O3' DG E 21 -17.172 -25.413 55.640 1.00148.68 O ANISOU 1417 O3' DG E 21 26360 23442 6690 -528 -123 -338 O ATOM 1418 C2' DG E 21 -14.928 -24.616 56.097 1.00154.01 C ANISOU 1418 C2' DG E 21 26997 24671 6848 -999 -1352 -739 C ATOM 1419 C1' DG E 21 -13.847 -25.129 57.053 1.00160.42 C ANISOU 1419 C1' DG E 21 27922 26100 6931 -1096 -2085 -499 C ATOM 1420 N9 DG E 21 -12.524 -25.281 56.412 1.00158.31 N ANISOU 1420 N9 DG E 21 27047 26035 7070 -1166 -2806 -409 N ATOM 1421 C8 DG E 21 -11.851 -26.442 56.094 1.00157.04 C ANISOU 1421 C8 DG E 21 26418 26070 7180 -887 -3241 191 C ATOM 1422 N7 DG E 21 -10.685 -26.244 55.529 1.00156.00 N ANISOU 1422 N7 DG E 21 25749 26126 7397 -1018 -3819 93 N ATOM 1423 C5 DG E 21 -10.568 -24.859 55.458 1.00156.05 C ANISOU 1423 C5 DG E 21 25895 26038 7361 -1462 -3772 -614 C ATOM 1424 C6 DG E 21 -9.524 -24.037 54.946 1.00155.59 C ANISOU 1424 C6 DG E 21 25447 26090 7578 -1836 -4212 -1028 C ATOM 1425 O6 DG E 21 -8.448 -24.378 54.432 1.00154.42 O ANISOU 1425 O6 DG E 21 24677 26211 7786 -1834 -4751 -854 O ATOM 1426 N1 DG E 21 -9.807 -22.674 55.075 1.00156.19 N ANISOU 1426 N1 DG E 21 25931 25926 7488 -2256 -3948 -1722 N ATOM 1427 C2 DG E 21 -10.962 -22.168 55.627 1.00157.46 C ANISOU 1427 C2 DG E 21 26770 25786 7273 -2251 -3325 -1990 C ATOM 1428 N2 DG E 21 -11.086 -20.834 55.673 1.00158.35 N ANISOU 1428 N2 DG E 21 27248 25633 7284 -2637 -3116 -2672 N ATOM 1429 N3 DG E 21 -11.941 -22.925 56.106 1.00157.92 N ANISOU 1429 N3 DG E 21 27133 25793 7075 -1889 -2902 -1613 N ATOM 1430 C4 DG E 21 -11.690 -24.256 55.995 1.00157.47 C ANISOU 1430 C4 DG E 21 26714 25954 7164 -1534 -3155 -929 C ATOM 1431 P DT E 22 -17.790 -25.397 54.149 1.00140.34 P ANISOU 1431 P DT E 22 24755 21873 6696 -347 253 -318 P ATOM 1432 OP1 DT E 22 -18.885 -26.393 54.132 1.00139.06 O ANISOU 1432 OP1 DT E 22 24558 21601 6677 -98 778 136 O ATOM 1433 OP2 DT E 22 -16.693 -25.527 53.162 1.00136.19 O ANISOU 1433 OP2 DT E 22 23679 21312 6754 -385 -312 -239 O ATOM 1434 O5' DT E 22 -18.447 -23.943 53.959 1.00139.69 O ANISOU 1434 O5' DT E 22 24891 21468 6718 -443 721 -980 O ATOM 1435 C5' DT E 22 -18.494 -22.942 54.992 1.00145.59 C ANISOU 1435 C5' DT E 22 26258 22331 6729 -650 829 -1492 C ATOM 1436 C4' DT E 22 -17.977 -21.599 54.484 1.00144.55 C ANISOU 1436 C4' DT E 22 26148 21935 6841 -887 682 -2095 C ATOM 1437 O4' DT E 22 -16.522 -21.606 54.443 1.00145.23 O ANISOU 1437 O4' DT E 22 26041 22298 6842 -1180 -108 -2110 O ATOM 1438 C3' DT E 22 -18.416 -21.185 53.077 1.00137.84 C ANISOU 1438 C3' DT E 22 24864 20574 6935 -725 967 -2174 C ATOM 1439 O3' DT E 22 -18.630 -19.758 53.057 1.00140.68 O ANISOU 1439 O3' DT E 22 25592 20593 7269 -850 1238 -2803 O ATOM 1440 C2' DT E 22 -17.231 -21.634 52.206 1.00132.82 C ANISOU 1440 C2' DT E 22 23666 20015 6785 -838 323 -1932 C ATOM 1441 C1' DT E 22 -16.077 -21.255 53.135 1.00138.68 C ANISOU 1441 C1' DT E 22 24706 21151 6834 -1220 -261 -2189 C ATOM 1442 N1 DT E 22 -14.727 -21.885 52.857 1.00136.66 N ANISOU 1442 N1 DT E 22 23977 21242 6705 -1353 -1013 -1906 N ATOM 1443 C2 DT E 22 -13.597 -21.067 52.788 1.00138.45 C ANISOU 1443 C2 DT E 22 24149 21582 6874 -1764 -1507 -2301 C ATOM 1444 O2 DT E 22 -13.612 -19.846 52.927 1.00140.86 O ANISOU 1444 O2 DT E 22 24823 21669 7029 -2059 -1372 -2877 O ATOM 1445 N3 DT E 22 -12.419 -21.736 52.543 1.00137.35 N ANISOU 1445 N3 DT E 22 23496 21819 6872 -1825 -2162 -1999 N ATOM 1446 C4 DT E 22 -12.256 -23.110 52.368 1.00135.26 C ANISOU 1446 C4 DT E 22 22831 21770 6791 -1481 -2360 -1356 C ATOM 1447 O4 DT E 22 -11.148 -23.597 52.157 1.00135.08 O ANISOU 1447 O4 DT E 22 22350 22081 6894 -1514 -2944 -1138 O ATOM 1448 C5 DT E 22 -13.470 -23.910 52.459 1.00133.08 C ANISOU 1448 C5 DT E 22 22715 21296 6553 -1091 -1817 -976 C ATOM 1449 C7 DT E 22 -13.433 -25.404 52.294 1.00131.17 C ANISOU 1449 C7 DT E 22 22157 21178 6503 -732 -1936 -288 C ATOM 1450 C6 DT E 22 -14.625 -23.267 52.693 1.00133.66 C ANISOU 1450 C6 DT E 22 23227 21060 6497 -1068 -1186 -1266 C ATOM 1451 P DA E 23 -19.043 -18.976 51.711 1.00135.57 P ANISOU 1451 P DA E 23 24665 19372 7475 -705 1533 -2997 P ATOM 1452 OP1 DA E 23 -20.521 -19.031 51.606 1.00134.45 O ANISOU 1452 OP1 DA E 23 24533 19024 7529 -298 2259 -2922 O ATOM 1453 OP2 DA E 23 -18.229 -19.497 50.582 1.00129.36 O ANISOU 1453 OP2 DA E 23 23253 18571 7327 -756 1068 -2686 O ATOM 1454 O5' DA E 23 -18.618 -17.452 52.027 1.00140.32 O ANISOU 1454 O5' DA E 23 25817 19707 7791 -1026 1519 -3699 O ATOM 1455 C5' DA E 23 -17.270 -17.092 52.390 1.00143.51 C ANISOU 1455 C5' DA E 23 26353 20331 7843 -1522 885 -3950 C ATOM 1456 C4' DA E 23 -16.431 -16.488 51.260 1.00139.81 C ANISOU 1456 C4' DA E 23 25563 19564 7994 -1765 575 -4098 C ATOM 1457 O4' DA E 23 -15.217 -17.260 51.034 1.00137.54 O ANISOU 1457 O4' DA E 23 24762 19705 7791 -1988 -119 -3785 O ATOM 1458 C3' DA E 23 -17.053 -16.309 49.877 1.00133.43 C ANISOU 1458 C3' DA E 23 24392 18251 8055 -1451 929 -3958 C ATOM 1459 O3' DA E 23 -16.617 -15.051 49.365 1.00135.76 O ANISOU 1459 O3' DA E 23 24912 18096 8573 -1733 923 -4416 O ATOM 1460 C2' DA E 23 -16.488 -17.480 49.066 1.00126.15 C ANISOU 1460 C2' DA E 23 22735 17590 7606 -1378 525 -3401 C ATOM 1461 C1' DA E 23 -15.080 -17.549 49.650 1.00129.27 C ANISOU 1461 C1' DA E 23 23111 18426 7578 -1843 -156 -3500 C ATOM 1462 N9 DA E 23 -14.374 -18.823 49.501 1.00125.12 N ANISOU 1462 N9 DA E 23 22026 18357 7156 -1783 -638 -2981 N ATOM 1463 C8 DA E 23 -14.862 -20.091 49.670 1.00122.30 C ANISOU 1463 C8 DA E 23 21458 18228 6783 -1421 -569 -2453 C ATOM 1464 N7 DA E 23 -13.967 -21.032 49.471 1.00120.55 N ANISOU 1464 N7 DA E 23 20769 18354 6680 -1421 -1074 -2070 N ATOM 1465 C5 DA E 23 -12.810 -20.334 49.157 1.00121.96 C ANISOU 1465 C5 DA E 23 20783 18598 6959 -1817 -1508 -2371 C ATOM 1466 C6 DA E 23 -11.493 -20.741 48.837 1.00121.97 C ANISOU 1466 C6 DA E 23 20265 18955 7122 -1995 -2121 -2216 C ATOM 1467 N6 DA E 23 -11.102 -22.019 48.779 1.00120.65 N ANISOU 1467 N6 DA E 23 19671 19119 7050 -1728 -2421 -1686 N ATOM 1468 N1 DA E 23 -10.581 -19.775 48.574 1.00124.66 N ANISOU 1468 N1 DA E 23 20538 19289 7538 -2458 -2397 -2632 N ATOM 1469 C2 DA E 23 -10.950 -18.487 48.626 1.00126.23 C ANISOU 1469 C2 DA E 23 21226 19087 7650 -2728 -2083 -3164 C ATOM 1470 N3 DA E 23 -12.153 -17.989 48.916 1.00126.42 N ANISOU 1470 N3 DA E 23 21794 18716 7522 -2543 -1507 -3353 N ATOM 1471 C4 DA E 23 -13.045 -18.969 49.172 1.00124.43 C ANISOU 1471 C4 DA E 23 21528 18544 7204 -2080 -1245 -2935 C ATOM 1472 P DT E 24 -17.493 -14.253 48.286 1.00133.13 P ANISOU 1472 P DT E 24 24609 17086 8890 -1412 1458 -4514 P ATOM 1473 OP1 DT E 24 -18.344 -13.341 49.095 1.00138.48 O ANISOU 1473 OP1 DT E 24 25992 17469 9155 -1278 1989 -4963 O ATOM 1474 OP2 DT E 24 -18.070 -15.231 47.325 1.00124.80 O ANISOU 1474 OP2 DT E 24 22914 16076 8429 -990 1563 -3959 O ATOM 1475 O5' DT E 24 -16.431 -13.359 47.485 1.00132.68 O ANISOU 1475 O5' DT E 24 24542 16703 9168 -1860 1151 -4782 O ATOM 1476 C5' DT E 24 -15.053 -13.351 47.851 1.00135.16 C ANISOU 1476 C5' DT E 24 24796 17367 9193 -2447 544 -4933 C ATOM 1477 C4' DT E 24 -14.213 -14.023 46.779 1.00129.04 C ANISOU 1477 C4' DT E 24 23279 16776 8975 -2538 130 -4542 C ATOM 1478 O4' DT E 24 -14.067 -15.447 47.001 1.00125.40 O ANISOU 1478 O4' DT E 24 22313 16891 8440 -2332 -163 -4039 O ATOM 1479 C3' DT E 24 -14.685 -13.885 45.335 1.00123.24 C ANISOU 1479 C3' DT E 24 22247 15569 9010 -2242 423 -4326 C ATOM 1480 O3' DT E 24 -13.785 -12.977 44.709 1.00126.15 O ANISOU 1480 O3' DT E 24 22667 15648 9616 -2707 254 -4603 O ATOM 1481 C2' DT E 24 -14.617 -15.313 44.766 1.00115.73 C ANISOU 1481 C2' DT E 24 20570 15011 8393 -1961 210 -3731 C ATOM 1482 C1' DT E 24 -13.650 -15.960 45.753 1.00118.05 C ANISOU 1482 C1' DT E 24 20747 15935 8169 -2258 -327 -3691 C ATOM 1483 N1 DT E 24 -13.589 -17.462 45.787 1.00112.76 N ANISOU 1483 N1 DT E 24 19563 15736 7544 -1974 -557 -3142 N ATOM 1484 C2 DT E 24 -12.358 -18.060 45.585 1.00111.83 C ANISOU 1484 C2 DT E 24 18948 16027 7516 -2192 -1112 -2953 C ATOM 1485 O2 DT E 24 -11.325 -17.442 45.382 1.00114.09 O ANISOU 1485 O2 DT E 24 19137 16363 7847 -2633 -1428 -3212 O ATOM 1486 N3 DT E 24 -12.369 -19.430 45.631 1.00108.46 N ANISOU 1486 N3 DT E 24 18128 15948 7133 -1874 -1274 -2445 N ATOM 1487 C4 DT E 24 -13.451 -20.259 45.851 1.00105.73 C ANISOU 1487 C4 DT E 24 17841 15582 6749 -1438 -944 -2113 C ATOM 1488 O4 DT E 24 -13.318 -21.481 45.869 1.00103.41 O ANISOU 1488 O4 DT E 24 17220 15565 6505 -1212 -1122 -1663 O ATOM 1489 C5 DT E 24 -14.713 -19.572 46.058 1.00106.36 C ANISOU 1489 C5 DT E 24 18390 15286 6735 -1275 -369 -2341 C ATOM 1490 C7 DT E 24 -15.976 -20.346 46.307 1.00104.49 C ANISOU 1490 C7 DT E 24 18202 15036 6463 -854 57 -2033 C ATOM 1491 C6 DT E 24 -14.722 -18.227 46.017 1.00109.46 C ANISOU 1491 C6 DT E 24 19166 15336 7089 -1512 -206 -2834 C ATOM 1492 P DA E 25 -13.849 -12.596 43.150 1.00122.79 P ANISOU 1492 P DA E 25 21997 14728 9928 -2604 439 -4451 P ATOM 1493 OP1 DA E 25 -13.467 -11.163 43.082 1.00127.45 O ANISOU 1493 OP1 DA E 25 23148 14791 10486 -3038 552 -4948 O ATOM 1494 OP2 DA E 25 -15.127 -13.074 42.558 1.00117.51 O ANISOU 1494 OP2 DA E 25 21164 13881 9605 -1942 848 -4097 O ATOM 1495 O5' DA E 25 -12.677 -13.494 42.514 1.00119.11 O ANISOU 1495 O5' DA E 25 20778 14735 9745 -2841 -80 -4122 O ATOM 1496 C5' DA E 25 -11.414 -13.626 43.203 1.00122.91 C ANISOU 1496 C5' DA E 25 21107 15720 9873 -3370 -616 -4280 C ATOM 1497 C4' DA E 25 -10.280 -14.035 42.274 1.00119.70 C ANISOU 1497 C4' DA E 25 20029 15560 9892 -3624 -980 -4067 C ATOM 1498 O4' DA E 25 -9.995 -15.443 42.460 1.00116.52 O ANISOU 1498 O4' DA E 25 19046 15761 9464 -3364 -1312 -3633 O ATOM 1499 C3' DA E 25 -10.467 -13.849 40.775 1.00114.53 C ANISOU 1499 C3' DA E 25 19152 14465 9897 -3476 -711 -3876 C ATOM 1500 O3' DA E 25 -9.194 -13.628 40.175 1.00116.41 O ANISOU 1500 O3' DA E 25 19018 14845 10368 -3984 -1009 -3944 O ATOM 1501 C2' DA E 25 -11.080 -15.185 40.362 1.00107.75 C ANISOU 1501 C2' DA E 25 17823 13834 9284 -2885 -664 -3350 C ATOM 1502 C1' DA E 25 -10.425 -16.174 41.324 1.00109.18 C ANISOU 1502 C1' DA E 25 17695 14701 9089 -2936 -1125 -3209 C ATOM 1503 N9 DA E 25 -11.323 -17.266 41.714 1.00105.42 N ANISOU 1503 N9 DA E 25 17148 14401 8505 -2403 -1008 -2847 N ATOM 1504 C8 DA E 25 -12.645 -17.192 42.082 1.00104.21 C ANISOU 1504 C8 DA E 25 17392 13991 8210 -2036 -580 -2842 C ATOM 1505 N7 DA E 25 -13.187 -18.359 42.362 1.00101.52 N ANISOU 1505 N7 DA E 25 16851 13909 7812 -1655 -556 -2464 N ATOM 1506 C5 DA E 25 -12.156 -19.268 42.160 1.00100.44 C ANISOU 1506 C5 DA E 25 16187 14186 7790 -1732 -1001 -2193 C ATOM 1507 C6 DA E 25 -12.064 -20.680 42.282 1.00 97.92 C ANISOU 1507 C6 DA E 25 15492 14225 7490 -1446 -1191 -1740 C ATOM 1508 N6 DA E 25 -13.066 -21.489 42.660 1.00 95.69 N ANISOU 1508 N6 DA E 25 15308 13952 7095 -1072 -947 -1460 N ATOM 1509 N1 DA E 25 -10.866 -21.243 41.997 1.00 98.22 N ANISOU 1509 N1 DA E 25 15039 14604 7677 -1564 -1631 -1580 N ATOM 1510 C2 DA E 25 -9.830 -20.480 41.618 1.00100.57 C ANISOU 1510 C2 DA E 25 15173 14944 8097 -1979 -1866 -1850 C ATOM 1511 N3 DA E 25 -9.796 -19.154 41.471 1.00102.83 N ANISOU 1511 N3 DA E 25 15786 14913 8372 -2342 -1719 -2280 N ATOM 1512 C4 DA E 25 -10.998 -18.604 41.757 1.00102.81 C ANISOU 1512 C4 DA E 25 16324 14520 8220 -2176 -1285 -2429 C ATOM 1513 P DG E 26 -8.959 -13.472 38.586 1.00112.90 P ANISOU 1513 P DG E 26 18256 14080 10563 -3996 -836 -3751 P ATOM 1514 OP1 DG E 26 -8.704 -12.032 38.360 1.00117.18 O ANISOU 1514 OP1 DG E 26 19312 14084 11126 -4491 -647 -4159 O ATOM 1515 OP2 DG E 26 -10.015 -14.155 37.792 1.00105.88 O ANISOU 1515 OP2 DG E 26 17218 13002 10010 -3344 -533 -3345 O ATOM 1516 O5' DG E 26 -7.600 -14.301 38.354 1.00112.63 O ANISOU 1516 O5' DG E 26 17431 14697 10665 -4261 -1319 -3571 O ATOM 1517 C5' DG E 26 -7.356 -15.539 39.044 1.00111.34 C ANISOU 1517 C5' DG E 26 16836 15173 10295 -4008 -1681 -3310 C ATOM 1518 C4' DG E 26 -7.139 -16.726 38.108 1.00105.30 C ANISOU 1518 C4' DG E 26 15395 14645 9971 -3641 -1741 -2845 C ATOM 1519 O4' DG E 26 -8.026 -17.825 38.463 1.00101.51 O ANISOU 1519 O4' DG E 26 14889 14278 9401 -3045 -1680 -2500 O ATOM 1520 C3' DG E 26 -7.360 -16.490 36.619 1.00100.57 C ANISOU 1520 C3' DG E 26 14695 13605 9910 -3556 -1396 -2719 C ATOM 1521 O3' DG E 26 -6.299 -17.178 35.938 1.00 99.57 O ANISOU 1521 O3' DG E 26 13869 13872 10092 -3640 -1631 -2523 O ATOM 1522 C2' DG E 26 -8.769 -17.050 36.384 1.00 95.03 C ANISOU 1522 C2' DG E 26 14183 12624 9300 -2925 -1063 -2443 C ATOM 1523 C1' DG E 26 -8.800 -18.231 37.351 1.00 94.66 C ANISOU 1523 C1' DG E 26 13918 13077 8970 -2640 -1336 -2221 C ATOM 1524 N9 DG E 26 -10.138 -18.636 37.811 1.00 91.51 N ANISOU 1524 N9 DG E 26 13836 12522 8411 -2177 -1074 -2075 N ATOM 1525 C8 DG E 26 -11.236 -17.828 38.032 1.00 91.27 C ANISOU 1525 C8 DG E 26 14364 12060 8253 -2065 -701 -2262 C ATOM 1526 N7 DG E 26 -12.296 -18.473 38.442 1.00 88.87 N ANISOU 1526 N7 DG E 26 14161 11771 7835 -1642 -511 -2066 N ATOM 1527 C5 DG E 26 -11.883 -19.799 38.496 1.00 87.01 C ANISOU 1527 C5 DG E 26 13462 11952 7646 -1479 -776 -1718 C ATOM 1528 C6 DG E 26 -12.600 -20.967 38.868 1.00 84.78 C ANISOU 1528 C6 DG E 26 13089 11835 7288 -1086 -711 -1382 C ATOM 1529 O6 DG E 26 -13.780 -21.071 39.243 1.00 84.01 O ANISOU 1529 O6 DG E 26 13257 11599 7063 -820 -397 -1330 O ATOM 1530 N1 DG E 26 -11.804 -22.110 38.780 1.00 83.80 N ANISOU 1530 N1 DG E 26 12508 12071 7261 -1014 -1035 -1081 N ATOM 1531 C2 DG E 26 -10.487 -22.138 38.389 1.00 85.17 C ANISOU 1531 C2 DG E 26 12291 12477 7593 -1254 -1379 -1104 C ATOM 1532 N2 DG E 26 -9.905 -23.346 38.377 1.00 84.94 N ANISOU 1532 N2 DG E 26 11848 12773 7651 -1057 -1636 -776 N ATOM 1533 N3 DG E 26 -9.801 -21.052 38.039 1.00 87.32 N ANISOU 1533 N3 DG E 26 12583 12655 7938 -1658 -1438 -1425 N ATOM 1534 C4 DG E 26 -10.557 -19.919 38.114 1.00 88.38 C ANISOU 1534 C4 DG E 26 13225 12383 7971 -1766 -1127 -1717 C ATOM 1535 P DA E 27 -6.335 -17.620 34.393 1.00 94.54 P ANISOU 1535 P DA E 27 12875 13049 9998 -3409 -1385 -2236 P ATOM 1536 OP1 DA E 27 -4.919 -17.685 33.961 1.00 96.75 O ANISOU 1536 OP1 DA E 27 12572 13716 10475 -3797 -1623 -2272 O ATOM 1537 OP2 DA E 27 -7.323 -16.805 33.636 1.00 91.25 O ANISOU 1537 OP2 DA E 27 12962 11973 9737 -3316 -937 -2283 O ATOM 1538 O5' DA E 27 -6.914 -19.114 34.479 1.00 89.24 O ANISOU 1538 O5' DA E 27 11933 12602 9373 -2774 -1430 -1829 O ATOM 1539 C5' DA E 27 -6.181 -20.129 35.187 1.00 89.47 C ANISOU 1539 C5' DA E 27 11519 13213 9261 -2665 -1833 -1666 C ATOM 1540 C4' DA E 27 -6.579 -21.523 34.723 1.00 83.37 C ANISOU 1540 C4' DA E 27 10449 12505 8722 -2106 -1772 -1252 C ATOM 1541 O4' DA E 27 -7.879 -21.889 35.259 1.00 80.25 O ANISOU 1541 O4' DA E 27 10462 11901 8130 -1738 -1588 -1122 O ATOM 1542 C3' DA E 27 -6.687 -21.693 33.214 1.00 78.43 C ANISOU 1542 C3' DA E 27 9621 11605 8575 -1988 -1478 -1122 C ATOM 1543 O3' DA E 27 -6.128 -22.952 32.871 1.00 76.94 O ANISOU 1543 O3' DA E 27 8910 11721 8604 -1693 -1618 -838 O ATOM 1544 C2' DA E 27 -8.189 -21.603 32.925 1.00 73.61 C ANISOU 1544 C2' DA E 27 9465 10519 7984 -1689 -1109 -1049 C ATOM 1545 C1' DA E 27 -8.793 -22.149 34.213 1.00 74.04 C ANISOU 1545 C1' DA E 27 9730 10732 7670 -1450 -1226 -960 C ATOM 1546 N9 DA E 27 -10.082 -21.556 34.559 1.00 71.69 N ANISOU 1546 N9 DA E 27 9965 10081 7194 -1343 -936 -1060 N ATOM 1547 C8 DA E 27 -10.446 -20.241 34.511 1.00 72.34 C ANISOU 1547 C8 DA E 27 10468 9812 7204 -1565 -735 -1352 C ATOM 1548 N7 DA E 27 -11.686 -20.031 34.882 1.00 71.13 N ANISOU 1548 N7 DA E 27 10703 9413 6909 -1319 -471 -1365 N ATOM 1549 C5 DA E 27 -12.163 -21.290 35.189 1.00 69.08 C ANISOU 1549 C5 DA E 27 10257 9369 6621 -970 -499 -1065 C ATOM 1550 C6 DA E 27 -13.407 -21.761 35.650 1.00 67.97 C ANISOU 1550 C6 DA E 27 10304 9166 6356 -636 -275 -925 C ATOM 1551 N6 DA E 27 -14.451 -20.974 35.890 1.00 68.82 N ANISOU 1551 N6 DA E 27 10804 8997 6348 -539 32 -1083 N ATOM 1552 N1 DA E 27 -13.548 -23.084 35.862 1.00 66.56 N ANISOU 1552 N1 DA E 27 9891 9214 6185 -397 -352 -612 N ATOM 1553 C2 DA E 27 -12.510 -23.892 35.632 1.00 66.53 C ANISOU 1553 C2 DA E 27 9503 9466 6310 -425 -642 -445 C ATOM 1554 N3 DA E 27 -11.294 -23.565 35.198 1.00 67.81 N ANISOU 1554 N3 DA E 27 9408 9750 6605 -678 -873 -554 N ATOM 1555 C4 DA E 27 -11.186 -22.241 34.995 1.00 69.12 C ANISOU 1555 C4 DA E 27 9801 9706 6754 -975 -785 -869 C HETATM 1556 N1 5CM E 28 -11.748 -23.713 31.434 1.00 58.51 N ANISOU 1556 N1 5CM E 28 7778 7947 6505 -501 -356 -373 N HETATM 1557 C2 5CM E 28 -12.938 -23.824 32.180 1.00 58.17 C ANISOU 1557 C2 5CM E 28 8022 7823 6257 -298 -214 -328 C HETATM 1558 N3 5CM E 28 -13.710 -22.750 32.434 1.00 59.25 N ANISOU 1558 N3 5CM E 28 8535 7723 6252 -333 -20 -518 N HETATM 1559 C4 5CM E 28 -13.352 -21.538 31.967 1.00 60.75 C ANISOU 1559 C4 5CM E 28 8889 7696 6496 -574 33 -743 C HETATM 1560 C5 5CM E 28 -12.099 -21.404 31.173 1.00 61.04 C ANISOU 1560 C5 5CM E 28 8651 7802 6739 -848 -114 -781 C HETATM 1561 C5A 5CM E 28 -11.650 -20.075 30.630 1.00 63.02 C ANISOU 1561 C5A 5CM E 28 9107 7787 7050 -1180 -28 -1011 C HETATM 1562 C6 5CM E 28 -11.339 -22.540 30.938 1.00 60.01 C ANISOU 1562 C6 5CM E 28 8077 7971 6752 -789 -302 -593 C HETATM 1563 O2 5CM E 28 -13.279 -24.934 32.617 1.00 57.40 O ANISOU 1563 O2 5CM E 28 7838 7863 6109 -77 -242 -107 O HETATM 1564 N4 5CM E 28 -14.136 -20.467 32.222 1.00 61.68 N ANISOU 1564 N4 5CM E 28 9427 7523 6485 -556 248 -927 N HETATM 1565 C1' 5CM E 28 -10.977 -24.921 31.196 1.00 57.96 C ANISOU 1565 C1' 5CM E 28 7298 8127 6597 -381 -528 -166 C HETATM 1566 C2' 5CM E 28 -10.298 -24.923 29.835 1.00 56.22 C ANISOU 1566 C2' 5CM E 28 6786 7854 6720 -467 -466 -170 C HETATM 1567 C3' 5CM E 28 -9.335 -26.065 30.038 1.00 57.97 C ANISOU 1567 C3' 5CM E 28 6607 8400 7020 -332 -693 -2 C HETATM 1568 C4' 5CM E 28 -9.012 -26.042 31.535 1.00 61.99 C ANISOU 1568 C4' 5CM E 28 7185 9193 7174 -374 -980 -17 C HETATM 1569 O4' 5CM E 28 -9.939 -25.139 32.146 1.00 61.64 O ANISOU 1569 O4' 5CM E 28 7595 8959 6868 -481 -858 -175 O HETATM 1570 O3' 5CM E 28 -10.086 -27.236 29.737 1.00 55.43 O ANISOU 1570 O3' 5CM E 28 6284 7955 6820 6 -564 232 O HETATM 1571 C5' 5CM E 28 -7.592 -25.578 31.826 1.00 66.28 C ANISOU 1571 C5' 5CM E 28 7421 10090 7671 -665 -1276 -166 C HETATM 1572 O5' 5CM E 28 -7.459 -24.274 31.274 1.00 67.49 O ANISOU 1572 O5' 5CM E 28 7704 10059 7878 -1049 -1140 -440 O HETATM 1573 P 5CM E 28 -6.085 -23.463 31.364 1.00 72.60 P ANISOU 1573 P 5CM E 28 8075 10997 8514 -1515 -1360 -676 P HETATM 1574 OP1 5CM E 28 -4.943 -24.439 31.283 1.00 73.90 O ANISOU 1574 OP1 5CM E 28 7628 11607 8843 -1376 -1604 -515 O HETATM 1575 OP2 5CM E 28 -6.197 -22.290 30.417 1.00 71.09 O ANISOU 1575 OP2 5CM E 28 8094 10447 8471 -1848 -1078 -880 O ATOM 1576 P DG E 29 -9.429 -28.556 29.180 1.00 55.66 P ANISOU 1576 P DG E 29 5958 8083 7106 249 -606 431 P ATOM 1577 OP1 DG E 29 -8.135 -28.769 29.855 1.00 59.43 O ANISOU 1577 OP1 DG E 29 6120 8938 7521 243 -919 459 O ATOM 1578 OP2 DG E 29 -9.524 -28.506 27.701 1.00 53.71 O ANISOU 1578 OP2 DG E 29 5630 7632 7146 218 -366 378 O ATOM 1579 O5' DG E 29 -10.459 -29.675 29.650 1.00 54.25 O ANISOU 1579 O5' DG E 29 5980 7768 6863 544 -526 667 O ATOM 1580 C5' DG E 29 -10.914 -29.752 30.981 1.00 55.69 C ANISOU 1580 C5' DG E 29 6396 8041 6723 594 -631 751 C ATOM 1581 C4' DG E 29 -12.351 -30.244 31.048 1.00 53.29 C ANISOU 1581 C4' DG E 29 6365 7494 6387 717 -383 869 C ATOM 1582 O4' DG E 29 -13.291 -29.154 31.198 1.00 52.37 O ANISOU 1582 O4' DG E 29 6503 7271 6125 571 -226 691 O ATOM 1583 C3' DG E 29 -12.889 -31.014 29.857 1.00 50.35 C ANISOU 1583 C3' DG E 29 5923 6876 6331 824 -161 945 C ATOM 1584 O3' DG E 29 -13.815 -31.956 30.373 1.00 50.39 O ANISOU 1584 O3' DG E 29 6107 6773 6265 959 -46 1146 O ATOM 1585 C2' DG E 29 -13.561 -29.930 29.018 1.00 47.61 C ANISOU 1585 C2' DG E 29 5655 6381 6053 658 18 739 C ATOM 1586 C1' DG E 29 -14.175 -29.059 30.098 1.00 48.03 C ANISOU 1586 C1' DG E 29 5967 6483 5800 583 23 654 C ATOM 1587 N9 DG E 29 -14.269 -27.620 29.872 1.00 46.94 N ANISOU 1587 N9 DG E 29 5954 6274 5606 409 75 417 N ATOM 1588 C8 DG E 29 -13.301 -26.771 29.395 1.00 47.03 C ANISOU 1588 C8 DG E 29 5881 6306 5683 212 -17 250 C ATOM 1589 N7 DG E 29 -13.687 -25.525 29.341 1.00 47.33 N ANISOU 1589 N7 DG E 29 6150 6194 5639 83 85 67 N ATOM 1590 C5 DG E 29 -14.981 -25.542 29.834 1.00 46.60 C ANISOU 1590 C5 DG E 29 6270 6013 5422 245 248 108 C ATOM 1591 C6 DG E 29 -15.906 -24.487 30.033 1.00 47.33 C ANISOU 1591 C6 DG E 29 6652 5932 5400 270 428 -28 C ATOM 1592 O6 DG E 29 -15.760 -23.282 29.793 1.00 49.01 O ANISOU 1592 O6 DG E 29 7056 5973 5594 145 477 -211 O ATOM 1593 N1 DG E 29 -17.114 -24.938 30.563 1.00 46.55 N ANISOU 1593 N1 DG E 29 6625 5851 5211 471 588 71 N ATOM 1594 C2 DG E 29 -17.385 -26.249 30.861 1.00 45.59 C ANISOU 1594 C2 DG E 29 6355 5864 5101 576 578 283 C ATOM 1595 N2 DG E 29 -18.592 -26.507 31.356 1.00 44.71 N ANISOU 1595 N2 DG E 29 6321 5766 4900 711 778 352 N ATOM 1596 N3 DG E 29 -16.532 -27.247 30.686 1.00 46.17 N ANISOU 1596 N3 DG E 29 6226 6039 5277 558 410 421 N ATOM 1597 C4 DG E 29 -15.351 -26.824 30.167 1.00 46.21 C ANISOU 1597 C4 DG E 29 6116 6063 5380 416 248 321 C HETATM 1598 N1 5CM E 30 -17.913 -28.674 27.790 1.00 41.43 N ANISOU 1598 N1 5CM E 30 5250 5175 5318 701 685 613 N HETATM 1599 C2 5CM E 30 -18.637 -27.475 27.956 1.00 42.28 C ANISOU 1599 C2 5CM E 30 5507 5238 5318 726 788 491 C HETATM 1600 N3 5CM E 30 -18.140 -26.290 27.565 1.00 42.10 N ANISOU 1600 N3 5CM E 30 5587 5121 5289 655 755 341 N HETATM 1601 C4 5CM E 30 -16.922 -26.219 27.008 1.00 41.80 C ANISOU 1601 C4 5CM E 30 5464 5075 5342 516 626 298 C HETATM 1602 C5 5CM E 30 -16.134 -27.459 26.818 1.00 41.43 C ANISOU 1602 C5 5CM E 30 5195 5133 5415 510 519 412 C HETATM 1603 C5A 5CM E 30 -14.761 -27.415 26.181 1.00 40.49 C ANISOU 1603 C5A 5CM E 30 4911 5055 5417 385 410 360 C HETATM 1604 C6 5CM E 30 -16.694 -28.659 27.242 1.00 41.45 C ANISOU 1604 C6 5CM E 30 5148 5179 5422 626 552 571 C HETATM 1605 O2 5CM E 30 -19.768 -27.491 28.474 1.00 43.77 O ANISOU 1605 O2 5CM E 30 5746 5461 5424 821 939 523 O HETATM 1606 N4 5CM E 30 -16.429 -25.026 26.618 1.00 42.49 N ANISOU 1606 N4 5CM E 30 5677 5047 5420 390 622 154 N HETATM 1607 C1' 5CM E 30 -18.503 -29.926 28.253 1.00 41.89 C ANISOU 1607 C1' 5CM E 30 5279 5262 5376 761 753 787 C HETATM 1608 C2' 5CM E 30 -18.712 -30.977 27.190 1.00 41.12 C ANISOU 1608 C2' 5CM E 30 5038 5067 5517 752 804 862 C HETATM 1609 C3' 5CM E 30 -18.475 -32.283 27.923 1.00 43.25 C ANISOU 1609 C3' 5CM E 30 5345 5323 5766 793 790 1050 C HETATM 1610 C4' 5CM E 30 -18.052 -31.889 29.319 1.00 45.05 C ANISOU 1610 C4' 5CM E 30 5708 5688 5720 833 693 1090 C HETATM 1611 O4' 5CM E 30 -17.615 -30.550 29.161 1.00 44.88 O ANISOU 1611 O4' 5CM E 30 5690 5723 5639 782 612 894 O HETATM 1612 O3' 5CM E 30 -19.684 -33.016 28.047 1.00 45.02 O ANISOU 1612 O3' 5CM E 30 5592 5503 6011 753 969 1148 O HETATM 1613 C5' 5CM E 30 -16.940 -32.748 29.894 1.00 46.33 C ANISOU 1613 C5' 5CM E 30 5873 5887 5843 922 519 1250 C HETATM 1614 O5' 5CM E 30 -15.796 -32.559 29.087 1.00 45.67 O ANISOU 1614 O5' 5CM E 30 5608 5814 5931 931 377 1157 O HETATM 1615 P 5CM E 30 -14.378 -33.153 29.500 1.00 48.25 P ANISOU 1615 P 5CM E 30 5818 6255 6261 1065 148 1275 P HETATM 1616 OP1 5CM E 30 -14.574 -34.352 30.367 1.00 50.16 O ANISOU 1616 OP1 5CM E 30 6209 6442 6407 1220 149 1548 O HETATM 1617 OP2 5CM E 30 -13.517 -33.287 28.281 1.00 47.29 O ANISOU 1617 OP2 5CM E 30 5458 6088 6421 1085 135 1186 O ATOM 1618 P DG E 31 -20.436 -33.517 26.756 1.00 44.61 P ANISOU 1618 P DG E 31 5413 5353 6184 657 1070 1098 P ATOM 1619 OP1 DG E 31 -21.218 -34.722 27.103 1.00 45.68 O ANISOU 1619 OP1 DG E 31 5593 5411 6353 565 1219 1241 O ATOM 1620 OP2 DG E 31 -19.485 -33.572 25.611 1.00 42.82 O ANISOU 1620 OP2 DG E 31 5114 5037 6118 665 969 1007 O ATOM 1621 O5' DG E 31 -21.430 -32.277 26.570 1.00 43.00 O ANISOU 1621 O5' DG E 31 5138 5283 5918 663 1136 975 O ATOM 1622 C5' DG E 31 -22.320 -31.907 27.606 1.00 43.40 C ANISOU 1622 C5' DG E 31 5229 5456 5805 696 1268 1009 C ATOM 1623 C4' DG E 31 -23.369 -30.926 27.114 1.00 42.98 C ANISOU 1623 C4' DG E 31 5050 5506 5775 757 1350 901 C ATOM 1624 O4' DG E 31 -22.794 -29.686 26.652 1.00 42.32 O ANISOU 1624 O4' DG E 31 5036 5373 5671 853 1244 773 O ATOM 1625 C3' DG E 31 -24.211 -31.394 25.953 1.00 43.05 C ANISOU 1625 C3' DG E 31 4837 5551 5968 670 1372 890 C ATOM 1626 O3' DG E 31 -25.508 -30.937 26.251 1.00 45.19 O ANISOU 1626 O3' DG E 31 4955 6008 6207 736 1519 883 O ATOM 1627 C2' DG E 31 -23.549 -30.742 24.726 1.00 41.13 C ANISOU 1627 C2' DG E 31 4599 5229 5800 710 1214 788 C ATOM 1628 C1' DG E 31 -22.974 -29.446 25.267 1.00 40.47 C ANISOU 1628 C1' DG E 31 4684 5110 5583 850 1183 722 C ATOM 1629 N9 DG E 31 -21.642 -29.011 24.837 1.00 38.72 N ANISOU 1629 N9 DG E 31 4579 4764 5368 821 1048 658 N ATOM 1630 C8 DG E 31 -20.571 -29.803 24.522 1.00 38.56 C ANISOU 1630 C8 DG E 31 4546 4677 5427 727 960 679 C ATOM 1631 N7 DG E 31 -19.486 -29.138 24.212 1.00 37.81 N ANISOU 1631 N7 DG E 31 4512 4526 5327 702 872 604 N ATOM 1632 C5 DG E 31 -19.850 -27.809 24.351 1.00 37.41 C ANISOU 1632 C5 DG E 31 4580 4456 5179 762 902 530 C ATOM 1633 C6 DG E 31 -19.086 -26.622 24.157 1.00 37.69 C ANISOU 1633 C6 DG E 31 4758 4395 5166 717 862 428 C ATOM 1634 O6 DG E 31 -17.903 -26.490 23.812 1.00 37.56 O ANISOU 1634 O6 DG E 31 4738 4347 5187 590 788 380 O ATOM 1635 N1 DG E 31 -19.834 -25.478 24.394 1.00 38.31 N ANISOU 1635 N1 DG E 31 4999 4404 5155 830 942 377 N ATOM 1636 C2 DG E 31 -21.149 -25.477 24.773 1.00 38.72 C ANISOU 1636 C2 DG E 31 5013 4524 5174 1002 1051 417 C ATOM 1637 N2 DG E 31 -21.690 -24.269 24.956 1.00 38.99 N ANISOU 1637 N2 DG E 31 5223 4457 5135 1156 1141 354 N ATOM 1638 N3 DG E 31 -21.867 -26.579 24.970 1.00 39.01 N ANISOU 1638 N3 DG E 31 4856 4708 5256 1014 1091 509 N ATOM 1639 C4 DG E 31 -21.168 -27.715 24.737 1.00 37.93 C ANISOU 1639 C4 DG E 31 4620 4590 5201 873 1011 563 C ATOM 1640 P DG E 32 -26.780 -31.368 25.407 1.00 46.91 P ANISOU 1640 P DG E 32 4854 6399 6570 636 1564 880 P ATOM 1641 OP1 DG E 32 -27.973 -31.143 26.253 1.00 49.88 O ANISOU 1641 OP1 DG E 32 5060 7000 6891 697 1780 911 O ATOM 1642 OP2 DG E 32 -26.535 -32.703 24.820 1.00 46.59 O ANISOU 1642 OP2 DG E 32 4805 6247 6649 377 1517 909 O ATOM 1643 O5' DG E 32 -26.750 -30.339 24.195 1.00 45.08 O ANISOU 1643 O5' DG E 32 4562 6184 6381 792 1401 791 O ATOM 1644 C5' DG E 32 -27.185 -29.011 24.269 1.00 46.13 C ANISOU 1644 C5' DG E 32 4685 6387 6454 1065 1426 756 C ATOM 1645 C4' DG E 32 -26.779 -28.369 22.960 1.00 46.08 C ANISOU 1645 C4' DG E 32 4730 6299 6480 1138 1240 720 C ATOM 1646 O4' DG E 32 -25.333 -28.271 22.911 1.00 43.84 O ANISOU 1646 O4' DG E 32 4727 5771 6159 1063 1161 683 O ATOM 1647 C3' DG E 32 -27.160 -29.160 21.707 1.00 46.91 C ANISOU 1647 C3' DG E 32 4628 6519 6675 963 1109 721 C ATOM 1648 O3' DG E 32 -27.754 -28.302 20.750 1.00 49.77 O ANISOU 1648 O3' DG E 32 4885 7004 7022 1153 994 733 O ATOM 1649 C2' DG E 32 -25.826 -29.669 21.185 1.00 43.78 C ANISOU 1649 C2' DG E 32 4454 5894 6288 796 1020 683 C ATOM 1650 C1' DG E 32 -24.969 -28.488 21.573 1.00 42.20 C ANISOU 1650 C1' DG E 32 4503 5525 6004 970 1023 667 C ATOM 1651 N9 DG E 32 -23.545 -28.726 21.433 1.00 40.23 N ANISOU 1651 N9 DG E 32 4440 5086 5758 850 972 631 N ATOM 1652 C8 DG E 32 -22.896 -29.928 21.348 1.00 40.02 C ANISOU 1652 C8 DG E 32 4407 4997 5803 677 963 628 C ATOM 1653 N7 DG E 32 -21.600 -29.825 21.208 1.00 38.70 N ANISOU 1653 N7 DG E 32 4367 4699 5639 646 922 593 N ATOM 1654 C5 DG E 32 -21.381 -28.464 21.200 1.00 37.94 C ANISOU 1654 C5 DG E 32 4389 4564 5462 746 904 565 C ATOM 1655 C6 DG E 32 -20.180 -27.748 21.069 1.00 37.44 C ANISOU 1655 C6 DG E 32 4466 4388 5372 707 874 513 C ATOM 1656 O6 DG E 32 -19.043 -28.196 20.942 1.00 37.73 O ANISOU 1656 O6 DG E 32 4490 4387 5460 604 849 484 O ATOM 1657 N1 DG E 32 -20.373 -26.381 21.105 1.00 37.88 N ANISOU 1657 N1 DG E 32 4679 4369 5345 799 892 492 N ATOM 1658 C2 DG E 32 -21.599 -25.785 21.245 1.00 40.04 C ANISOU 1658 C2 DG E 32 4958 4681 5575 984 934 527 C ATOM 1659 N2 DG E 32 -21.620 -24.452 21.264 1.00 41.05 N ANISOU 1659 N2 DG E 32 5301 4662 5633 1099 969 504 N ATOM 1660 N3 DG E 32 -22.744 -26.442 21.358 1.00 40.85 N ANISOU 1660 N3 DG E 32 4859 4951 5711 1054 956 578 N ATOM 1661 C4 DG E 32 -22.561 -27.779 21.330 1.00 39.42 C ANISOU 1661 C4 DG E 32 4539 4836 5603 893 939 590 C ATOM 1662 P DT E 33 -29.345 -28.278 20.560 1.00 54.10 P ANISOU 1662 P DT E 33 5013 7923 7619 1256 989 772 P ATOM 1663 OP1 DT E 33 -30.001 -28.517 21.873 1.00 54.87 O ANISOU 1663 OP1 DT E 33 4958 8141 7747 1269 1222 785 O ATOM 1664 OP2 DT E 33 -29.633 -29.162 19.412 1.00 54.86 O ANISOU 1664 OP2 DT E 33 4925 8176 7743 995 815 742 O ATOM 1665 O5' DT E 33 -29.611 -26.759 20.114 1.00 54.59 O ANISOU 1665 O5' DT E 33 5141 7979 7620 1673 921 827 O ATOM 1666 C5' DT E 33 -29.083 -25.644 20.841 1.00 54.64 C ANISOU 1666 C5' DT E 33 5469 7722 7569 1924 1046 820 C ATOM 1667 C4' DT E 33 -28.470 -24.595 19.920 1.00 55.37 C ANISOU 1667 C4' DT E 33 5865 7585 7588 2088 921 859 C ATOM 1668 O4' DT E 33 -27.046 -24.871 19.712 1.00 52.43 O ANISOU 1668 O4' DT E 33 5794 6950 7178 1812 884 801 O ATOM 1669 C3' DT E 33 -29.070 -24.490 18.516 1.00 57.65 C ANISOU 1669 C3' DT E 33 5987 8071 7848 2181 700 955 C ATOM 1670 O3' DT E 33 -28.994 -23.153 18.027 1.00 60.24 O ANISOU 1670 O3' DT E 33 6582 8206 8099 2516 663 1051 O ATOM 1671 C2' DT E 33 -28.109 -25.365 17.716 1.00 54.38 C ANISOU 1671 C2' DT E 33 5692 7575 7396 1801 586 900 C ATOM 1672 C1' DT E 33 -26.774 -24.941 18.329 1.00 50.98 C ANISOU 1672 C1' DT E 33 5650 6772 6947 1730 712 842 C ATOM 1673 N1 DT E 33 -25.659 -25.913 18.122 1.00 47.46 N ANISOU 1673 N1 DT E 33 5292 6225 6517 1382 699 760 N ATOM 1674 C2 DT E 33 -24.349 -25.471 18.085 1.00 45.89 C ANISOU 1674 C2 DT E 33 5394 5759 6283 1295 737 723 C ATOM 1675 O2 DT E 33 -24.028 -24.297 18.211 1.00 47.53 O ANISOU 1675 O2 DT E 33 5847 5773 6437 1435 781 744 O ATOM 1676 N3 DT E 33 -23.412 -26.461 17.891 1.00 43.01 N ANISOU 1676 N3 DT E 33 5030 5353 5957 1029 735 653 N ATOM 1677 C4 DT E 33 -23.661 -27.816 17.722 1.00 43.55 C ANISOU 1677 C4 DT E 33 4905 5550 6090 853 712 614 C ATOM 1678 O4 DT E 33 -22.757 -28.638 17.545 1.00 42.65 O ANISOU 1678 O4 DT E 33 4837 5348 6021 674 736 551 O ATOM 1679 C5 DT E 33 -25.058 -28.207 17.766 1.00 44.83 C ANISOU 1679 C5 DT E 33 4802 5954 6276 892 675 645 C ATOM 1680 C7 DT E 33 -25.466 -29.644 17.602 1.00 45.14 C ANISOU 1680 C7 DT E 33 4657 6109 6387 644 666 589 C ATOM 1681 C6 DT E 33 -25.970 -27.252 17.965 1.00 46.71 C ANISOU 1681 C6 DT E 33 4963 6302 6482 1150 665 717 C ATOM 1682 P DG E 34 -30.230 -22.131 17.977 1.00 65.27 P ANISOU 1682 P DG E 34 7063 8986 8751 3044 659 1180 P ATOM 1683 OP1 DG E 34 -30.541 -21.723 19.367 1.00 66.55 O ANISOU 1683 OP1 DG E 34 7233 9069 8983 3241 928 1103 O ATOM 1684 OP2 DG E 34 -31.286 -22.709 17.108 1.00 67.74 O ANISOU 1684 OP2 DG E 34 6901 9769 9068 3065 433 1262 O ATOM 1685 O5' DG E 34 -29.566 -20.871 17.231 1.00 65.18 O ANISOU 1685 O5' DG E 34 7558 8584 8622 3255 611 1291 O ATOM 1686 C5' DG E 34 -28.351 -20.286 17.718 1.00 62.30 C ANISOU 1686 C5' DG E 34 7690 7756 8226 3120 769 1205 C ATOM 1687 C4' DG E 34 -27.379 -19.967 16.584 1.00 61.48 C ANISOU 1687 C4' DG E 34 7943 7418 7999 2946 663 1280 C ATOM 1688 O4' DG E 34 -26.580 -21.127 16.224 1.00 57.50 O ANISOU 1688 O4' DG E 34 7339 7025 7484 2484 595 1182 O ATOM 1689 C3' DG E 34 -27.958 -19.504 15.245 1.00 64.45 C ANISOU 1689 C3' DG E 34 8339 7897 8252 3202 462 1501 C ATOM 1690 O3' DG E 34 -26.942 -18.774 14.566 1.00 65.02 O ANISOU 1690 O3' DG E 34 8916 7589 8198 3095 493 1572 O ATOM 1691 C2' DG E 34 -28.164 -20.834 14.531 1.00 62.16 C ANISOU 1691 C2' DG E 34 7666 8025 7927 2902 263 1464 C ATOM 1692 C1' DG E 34 -26.816 -21.460 14.865 1.00 56.78 C ANISOU 1692 C1' DG E 34 7162 7137 7276 2442 390 1288 C ATOM 1693 N9 DG E 34 -26.779 -22.908 14.785 1.00 53.38 N ANISOU 1693 N9 DG E 34 6416 6975 6890 2100 325 1163 N ATOM 1694 C8 DG E 34 -27.850 -23.773 14.745 1.00 54.20 C ANISOU 1694 C8 DG E 34 6081 7471 7042 2082 209 1144 C ATOM 1695 N7 DG E 34 -27.493 -25.027 14.690 1.00 51.34 N ANISOU 1695 N7 DG E 34 5592 7196 6718 1710 205 1011 N ATOM 1696 C5 DG E 34 -26.115 -24.974 14.700 1.00 47.59 C ANISOU 1696 C5 DG E 34 5451 6403 6226 1527 317 948 C ATOM 1697 C6 DG E 34 -25.195 -26.026 14.658 1.00 45.69 C ANISOU 1697 C6 DG E 34 5241 6092 6028 1190 374 815 C ATOM 1698 O6 DG E 34 -25.442 -27.233 14.602 1.00 45.97 O ANISOU 1698 O6 DG E 34 5074 6276 6117 976 346 724 O ATOM 1699 N1 DG E 34 -23.884 -25.560 14.688 1.00 44.21 N ANISOU 1699 N1 DG E 34 5353 5619 5824 1112 485 791 N ATOM 1700 C2 DG E 34 -23.513 -24.242 14.755 1.00 44.34 C ANISOU 1700 C2 DG E 34 5647 5414 5785 1271 543 871 C ATOM 1701 N2 DG E 34 -22.198 -24.010 14.772 1.00 43.41 N ANISOU 1701 N2 DG E 34 5750 5074 5670 1091 654 815 N ATOM 1702 N3 DG E 34 -24.376 -23.238 14.793 1.00 46.38 N ANISOU 1702 N3 DG E 34 5958 5667 6000 1585 505 996 N ATOM 1703 C4 DG E 34 -25.652 -23.685 14.762 1.00 48.45 C ANISOU 1703 C4 DG E 34 5888 6239 6283 1726 388 1033 C ATOM 1704 P DA E 35 -27.018 -17.193 14.347 1.00 69.91 P ANISOU 1704 P DA E 35 10030 7785 8748 3490 575 1756 P ATOM 1705 OP1 DA E 35 -27.313 -16.583 15.664 1.00 71.55 O ANISOU 1705 OP1 DA E 35 10312 7779 9095 3729 790 1644 O ATOM 1706 OP2 DA E 35 -27.896 -16.927 13.184 1.00 73.33 O ANISOU 1706 OP2 DA E 35 10391 8431 9041 3840 343 2023 O ATOM 1707 O5' DA E 35 -25.510 -16.831 13.945 1.00 67.34 O ANISOU 1707 O5' DA E 35 10200 7056 8330 3079 692 1721 O ATOM 1708 C5' DA E 35 -24.439 -17.177 14.810 1.00 62.59 C ANISOU 1708 C5' DA E 35 9641 6317 7824 2665 849 1479 C ATOM 1709 C4' DA E 35 -23.138 -17.361 14.039 1.00 60.38 C ANISOU 1709 C4' DA E 35 9564 5925 7453 2217 880 1458 C ATOM 1710 O4' DA E 35 -23.000 -18.698 13.496 1.00 57.12 O ANISOU 1710 O4' DA E 35 8782 5900 7022 1972 753 1398 O ATOM 1711 C3' DA E 35 -22.909 -16.453 12.842 1.00 63.33 C ANISOU 1711 C3' DA E 35 10377 6046 7641 2273 889 1687 C ATOM 1712 O3' DA E 35 -21.497 -16.236 12.813 1.00 63.11 O ANISOU 1712 O3' DA E 35 10614 5757 7606 1820 1066 1582 O ATOM 1713 C2' DA E 35 -23.479 -17.281 11.682 1.00 62.72 C ANISOU 1713 C2' DA E 35 10027 6390 7415 2322 661 1811 C ATOM 1714 C1' DA E 35 -23.095 -18.706 12.082 1.00 57.82 C ANISOU 1714 C1' DA E 35 8971 6087 6910 1979 637 1568 C ATOM 1715 N9 DA E 35 -24.052 -19.785 11.836 1.00 55.90 N ANISOU 1715 N9 DA E 35 8274 6300 6666 2057 431 1549 N ATOM 1716 C8 DA E 35 -25.417 -19.718 11.710 1.00 57.78 C ANISOU 1716 C8 DA E 35 8274 6798 6882 2427 248 1675 C ATOM 1717 N7 DA E 35 -25.995 -20.887 11.532 1.00 56.10 N ANISOU 1717 N7 DA E 35 7634 6997 6685 2313 93 1587 N ATOM 1718 C5 DA E 35 -24.941 -21.779 11.558 1.00 52.34 C ANISOU 1718 C5 DA E 35 7161 6479 6246 1883 195 1399 C ATOM 1719 C6 DA E 35 -24.882 -23.176 11.430 1.00 50.31 C ANISOU 1719 C6 DA E 35 6617 6472 6028 1586 144 1230 C ATOM 1720 N6 DA E 35 -25.956 -23.942 11.249 1.00 52.16 N ANISOU 1720 N6 DA E 35 6488 7071 6261 1605 -36 1206 N ATOM 1721 N1 DA E 35 -23.672 -23.761 11.501 1.00 48.37 N ANISOU 1721 N1 DA E 35 6467 6080 5832 1263 294 1080 N ATOM 1722 C2 DA E 35 -22.586 -22.996 11.688 1.00 48.25 C ANISOU 1722 C2 DA E 35 6755 5751 5828 1196 467 1090 C ATOM 1723 N3 DA E 35 -22.514 -21.669 11.828 1.00 49.67 N ANISOU 1723 N3 DA E 35 7234 5670 5968 1380 532 1223 N ATOM 1724 C4 DA E 35 -23.740 -21.121 11.748 1.00 51.99 C ANISOU 1724 C4 DA E 35 7482 6058 6211 1742 395 1379 C ATOM 1725 P DC E 36 -20.714 -15.542 11.598 1.00 66.47 P ANISOU 1725 P DC E 36 11498 5922 7837 1617 1168 1757 P ATOM 1726 OP1 DC E 36 -19.416 -15.038 12.107 1.00 66.52 O ANISOU 1726 OP1 DC E 36 11747 5602 7923 1188 1399 1599 O ATOM 1727 OP2 DC E 36 -21.638 -14.637 10.868 1.00 70.15 O ANISOU 1727 OP2 DC E 36 12292 6222 8139 2063 1092 2068 O ATOM 1728 O5' DC E 36 -20.381 -16.804 10.682 1.00 63.63 O ANISOU 1728 O5' DC E 36 10810 5987 7378 1365 1068 1719 O ATOM 1729 C5' DC E 36 -19.388 -17.744 11.062 1.00 59.65 C ANISOU 1729 C5' DC E 36 10018 5646 7002 969 1146 1473 C ATOM 1730 C4' DC E 36 -19.192 -18.721 9.918 1.00 58.75 C ANISOU 1730 C4' DC E 36 9741 5845 6738 813 1089 1477 C ATOM 1731 O4' DC E 36 -20.384 -19.525 9.748 1.00 57.82 O ANISOU 1731 O4' DC E 36 9312 6069 6587 1069 847 1498 O ATOM 1732 C3' DC E 36 -18.962 -18.088 8.551 1.00 61.72 C ANISOU 1732 C3' DC E 36 10520 6108 6821 762 1154 1693 C ATOM 1733 O3' DC E 36 -18.085 -18.951 7.868 1.00 61.28 O ANISOU 1733 O3' DC E 36 10338 6251 6696 427 1257 1568 O ATOM 1734 C2' DC E 36 -20.350 -18.087 7.922 1.00 62.62 C ANISOU 1734 C2' DC E 36 10622 6422 6750 1167 885 1897 C ATOM 1735 C1' DC E 36 -20.806 -19.456 8.402 1.00 58.31 C ANISOU 1735 C1' DC E 36 9535 6262 6357 1153 733 1680 C ATOM 1736 N1 DC E 36 -22.271 -19.767 8.343 1.00 57.57 N ANISOU 1736 N1 DC E 36 9178 6470 6225 1502 448 1763 N ATOM 1737 C2 DC E 36 -22.642 -21.124 8.365 1.00 54.92 C ANISOU 1737 C2 DC E 36 8417 6504 5945 1380 318 1580 C ATOM 1738 O2 DC E 36 -21.778 -22.009 8.430 1.00 51.76 O ANISOU 1738 O2 DC E 36 7910 6132 5623 1055 444 1374 O ATOM 1739 N3 DC E 36 -23.953 -21.442 8.309 1.00 55.63 N ANISOU 1739 N3 DC E 36 8215 6911 6011 1623 64 1634 N ATOM 1740 C4 DC E 36 -24.879 -20.488 8.235 1.00 58.57 C ANISOU 1740 C4 DC E 36 8661 7278 6314 2034 -71 1868 C ATOM 1741 N4 DC E 36 -26.153 -20.898 8.184 1.00 60.15 N ANISOU 1741 N4 DC E 36 8472 7871 6510 2249 -328 1902 N ATOM 1742 C5 DC E 36 -24.527 -19.099 8.214 1.00 60.63 C ANISOU 1742 C5 DC E 36 9390 7126 6521 2233 63 2073 C ATOM 1743 C6 DC E 36 -23.223 -18.787 8.273 1.00 59.58 C ANISOU 1743 C6 DC E 36 9585 6647 6406 1924 325 2005 C ATOM 1744 P DA E 37 -16.530 -18.597 7.811 1.00 61.76 P ANISOU 1744 P DA E 37 10545 6117 6805 -7 1575 1480 P ATOM 1745 OP1 DA E 37 -16.079 -18.293 9.192 1.00 61.07 O ANISOU 1745 OP1 DA E 37 10336 5860 7008 -98 1633 1326 O ATOM 1746 OP2 DA E 37 -16.345 -17.597 6.743 1.00 64.92 O ANISOU 1746 OP2 DA E 37 11454 6292 6921 -69 1711 1727 O ATOM 1747 O5' DA E 37 -15.900 -19.995 7.348 1.00 59.15 O ANISOU 1747 O5' DA E 37 9861 6130 6482 -222 1632 1274 O ATOM 1748 C5' DA E 37 -16.018 -21.149 8.184 1.00 54.88 C ANISOU 1748 C5' DA E 37 8869 5802 6181 -174 1521 1061 C ATOM 1749 C4' DA E 37 -15.968 -22.451 7.390 1.00 54.21 C ANISOU 1749 C4' DA E 37 8590 6003 6005 -236 1515 933 C ATOM 1750 O4' DA E 37 -17.271 -22.813 6.855 1.00 54.11 O ANISOU 1750 O4' DA E 37 8587 6165 5808 -12 1262 1010 O ATOM 1751 C3' DA E 37 -15.050 -22.492 6.171 1.00 56.25 C ANISOU 1751 C3' DA E 37 9026 6302 6045 -482 1763 922 C ATOM 1752 O3' DA E 37 -14.623 -23.845 6.029 1.00 55.17 O ANISOU 1752 O3' DA E 37 8599 6370 5994 -561 1831 690 O ATOM 1753 C2' DA E 37 -15.962 -22.023 5.031 1.00 58.06 C ANISOU 1753 C2' DA E 37 9609 6566 5887 -346 1630 1139 C ATOM 1754 C1' DA E 37 -17.317 -22.592 5.445 1.00 56.15 C ANISOU 1754 C1' DA E 37 9146 6491 5696 -65 1289 1127 C ATOM 1755 N9 DA E 37 -18.478 -21.733 5.227 1.00 56.75 N ANISOU 1755 N9 DA E 37 9426 6541 5595 226 1053 1385 N ATOM 1756 C8 DA E 37 -18.516 -20.376 5.084 1.00 58.92 C ANISOU 1756 C8 DA E 37 10083 6548 5756 339 1097 1643 C ATOM 1757 N7 DA E 37 -19.726 -19.892 4.929 1.00 60.45 N ANISOU 1757 N7 DA E 37 10357 6789 5820 690 835 1854 N ATOM 1758 C5 DA E 37 -20.542 -21.007 4.990 1.00 58.64 C ANISOU 1758 C5 DA E 37 9731 6922 5626 764 598 1709 C ATOM 1759 C6 DA E 37 -21.939 -21.183 4.899 1.00 59.62 C ANISOU 1759 C6 DA E 37 9653 7324 5676 1063 260 1798 C ATOM 1760 N6 DA E 37 -22.806 -20.185 4.723 1.00 62.89 N ANISOU 1760 N6 DA E 37 10231 7699 5964 1439 84 2087 N ATOM 1761 N1 DA E 37 -22.432 -22.432 4.994 1.00 58.24 N ANISOU 1761 N1 DA E 37 9083 7474 5571 968 112 1583 N ATOM 1762 C2 DA E 37 -21.572 -23.445 5.165 1.00 56.05 C ANISOU 1762 C2 DA E 37 8676 7192 5427 647 298 1310 C ATOM 1763 N3 DA E 37 -20.244 -23.405 5.269 1.00 54.99 N ANISOU 1763 N3 DA E 37 8682 6830 5382 416 606 1215 N ATOM 1764 C4 DA E 37 -19.786 -22.147 5.169 1.00 56.32 C ANISOU 1764 C4 DA E 37 9192 6730 5477 466 739 1419 C ATOM 1765 P DC E 38 -13.664 -24.308 4.842 1.00 58.02 P ANISOU 1765 P DC E 38 9039 6842 6165 -783 2128 583 P ATOM 1766 OP1 DC E 38 -12.775 -25.371 5.346 1.00 57.10 O ANISOU 1766 OP1 DC E 38 8547 6811 6336 -841 2279 339 O ATOM 1767 OP2 DC E 38 -13.071 -23.108 4.216 1.00 61.10 O ANISOU 1767 OP2 DC E 38 9765 7094 6357 -967 2344 758 O ATOM 1768 O5' DC E 38 -14.687 -24.956 3.795 1.00 59.15 O ANISOU 1768 O5' DC E 38 9338 7164 5972 -685 1951 574 O ATOM 1769 C5' DC E 38 -15.153 -26.294 3.935 1.00 56.17 C ANISOU 1769 C5' DC E 38 8726 6929 5688 -619 1827 362 C ATOM 1770 C4' DC E 38 -16.366 -26.506 3.054 1.00 57.42 C ANISOU 1770 C4' DC E 38 9061 7259 5495 -552 1565 407 C ATOM 1771 O4' DC E 38 -17.295 -25.419 3.260 1.00 57.76 O ANISOU 1771 O4' DC E 38 9222 7270 5455 -365 1310 685 O ATOM 1772 C3' DC E 38 -16.075 -26.438 1.566 1.00 61.04 C ANISOU 1772 C3' DC E 38 9866 7828 5497 -699 1710 408 C ATOM 1773 O3' DC E 38 -15.820 -27.741 1.090 1.00 61.99 O ANISOU 1773 O3' DC E 38 9923 8057 5574 -815 1829 104 O ATOM 1774 C2' DC E 38 -17.350 -25.856 0.955 1.00 62.90 C ANISOU 1774 C2' DC E 38 10320 8204 5374 -560 1357 633 C ATOM 1775 C1' DC E 38 -18.173 -25.402 2.159 1.00 59.45 C ANISOU 1775 C1' DC E 38 9646 7690 5252 -323 1096 772 C ATOM 1776 N1 DC E 38 -18.767 -24.034 2.011 1.00 60.19 N ANISOU 1776 N1 DC E 38 9992 7709 5170 -114 937 1122 N ATOM 1777 C2 DC E 38 -20.158 -23.886 1.893 1.00 60.68 C ANISOU 1777 C2 DC E 38 9992 7971 5094 133 547 1267 C ATOM 1778 O2 DC E 38 -20.881 -24.887 1.912 1.00 59.64 O ANISOU 1778 O2 DC E 38 9585 8093 4983 109 340 1088 O ATOM 1779 N3 DC E 38 -20.681 -22.641 1.758 1.00 62.01 N ANISOU 1779 N3 DC E 38 10399 8045 5116 396 414 1603 N ATOM 1780 C4 DC E 38 -19.884 -21.571 1.736 1.00 62.97 C ANISOU 1780 C4 DC E 38 10869 7838 5219 370 666 1786 C ATOM 1781 N4 DC E 38 -20.450 -20.370 1.601 1.00 64.99 N ANISOU 1781 N4 DC E 38 11414 7945 5335 660 542 2126 N ATOM 1782 C5 DC E 38 -18.468 -21.694 1.856 1.00 62.06 C ANISOU 1782 C5 DC E 38 10809 7532 5239 46 1065 1626 C ATOM 1783 C6 DC E 38 -17.961 -22.929 1.988 1.00 60.53 C ANISOU 1783 C6 DC E 38 10319 7484 5195 -161 1177 1302 C TER 1784 DC E 38 HETATM 1785 ZN ZN A 701 -12.098 -10.193 19.772 1.00 47.58 ZN HETATM 1786 ZN ZN A 702 -0.670 -32.250 17.520 1.00 46.36 ZN HETATM 1787 ZN ZN A 703 -25.854 -46.756 18.734 1.00 42.79 ZN HETATM 1788 C1 GOL A 704 -11.048 -26.274 16.925 1.00 56.55 C HETATM 1789 O1 GOL A 704 -12.390 -25.930 17.246 1.00 55.85 O HETATM 1790 C2 GOL A 704 -10.181 -25.046 16.638 1.00 56.28 C HETATM 1791 O2 GOL A 704 -10.895 -24.077 15.897 1.00 56.57 O HETATM 1792 C3 GOL A 704 -8.898 -25.439 15.904 1.00 56.17 C HETATM 1793 O3 GOL A 704 -7.877 -24.512 16.246 1.00 55.96 O HETATM 1794 C1 GOL D 101 -19.630 -24.195 9.089 1.00 57.45 C HETATM 1795 O1 GOL D 101 -19.248 -22.863 9.398 1.00 57.32 O HETATM 1796 C2 GOL D 101 -18.856 -25.165 9.973 1.00 56.89 C HETATM 1797 O2 GOL D 101 -18.865 -24.669 11.306 1.00 56.90 O HETATM 1798 C3 GOL D 101 -17.437 -25.249 9.413 1.00 56.16 C HETATM 1799 O3 GOL D 101 -17.444 -26.190 8.362 1.00 55.03 O HETATM 1800 O HOH A 801 -15.424 -41.616 16.170 1.00 21.56 O HETATM 1801 O HOH A 802 -11.084 -45.837 23.906 0.50 9.65 O HETATM 1802 O HOH A 803 -12.727 -39.483 22.631 1.00 20.01 O HETATM 1803 O HOH A 804 -20.987 -35.531 12.455 1.00 24.28 O HETATM 1804 O HOH A 805 -1.124 -34.225 27.694 1.00 23.85 O HETATM 1805 O HOH A 806 -23.319 -44.528 13.077 1.00 25.66 O HETATM 1806 O HOH A 807 -0.310 -23.247 28.721 1.00 22.57 O HETATM 1807 O HOH A 808 -12.831 -33.671 17.837 1.00 25.95 O HETATM 1808 O HOH A 809 -29.391 -32.321 19.595 1.00 23.78 O HETATM 1809 O HOH A 810 -10.062 -46.947 32.045 1.00 24.02 O HETATM 1810 O HOH A 811 -7.017 -46.382 32.875 1.00 18.43 O HETATM 1811 O HOH A 812 -9.438 -7.460 28.029 1.00 15.47 O HETATM 1812 O HOH A 813 -17.439 -47.901 16.857 1.00 27.09 O HETATM 1813 O HOH D 201 -19.271 -26.382 6.320 1.00 22.98 O HETATM 1814 O HOH E 101 -16.533 -29.019 23.029 1.00 27.42 O CONECT 138 1785 CONECT 159 1785 CONECT 271 1785 CONECT 308 1785 CONECT 380 1786 CONECT 409 1786 CONECT 523 1786 CONECT 560 1786 CONECT 629 1787 CONECT 648 1787 CONECT 756 1787 CONECT 796 1787 CONECT 1151 1179 CONECT 1162 1163 1168 1171 CONECT 1163 1162 1164 1169 CONECT 1164 1163 1165 CONECT 1165 1164 1166 1170 CONECT 1166 1165 1167 1168 CONECT 1167 1166 CONECT 1168 1162 1166 CONECT 1169 1163 CONECT 1170 1165 CONECT 1171 1162 1172 1175 CONECT 1172 1171 1173 CONECT 1173 1172 1174 1176 CONECT 1174 1173 1175 1177 CONECT 1175 1171 1174 CONECT 1176 1173 1182 CONECT 1177 1174 1178 CONECT 1178 1177 1179 CONECT 1179 1151 1178 1180 1181 CONECT 1180 1179 CONECT 1181 1179 CONECT 1182 1176 CONECT 1190 1221 CONECT 1204 1205 1210 1213 CONECT 1205 1204 1206 1211 CONECT 1206 1205 1207 CONECT 1207 1206 1208 1212 CONECT 1208 1207 1209 1210 CONECT 1209 1208 CONECT 1210 1204 1208 CONECT 1211 1205 CONECT 1212 1207 CONECT 1213 1204 1214 1217 CONECT 1214 1213 1215 CONECT 1215 1214 1216 1218 CONECT 1216 1215 1217 1219 CONECT 1217 1213 1216 CONECT 1218 1215 1224 CONECT 1219 1216 1220 CONECT 1220 1219 1221 CONECT 1221 1190 1220 1222 1223 CONECT 1222 1221 CONECT 1223 1221 CONECT 1224 1218 CONECT 1543 1573 CONECT 1556 1557 1562 1565 CONECT 1557 1556 1558 1563 CONECT 1558 1557 1559 CONECT 1559 1558 1560 1564 CONECT 1560 1559 1561 1562 CONECT 1561 1560 CONECT 1562 1556 1560 CONECT 1563 1557 CONECT 1564 1559 CONECT 1565 1556 1566 1569 CONECT 1566 1565 1567 CONECT 1567 1566 1568 1570 CONECT 1568 1567 1569 1571 CONECT 1569 1565 1568 CONECT 1570 1567 1576 CONECT 1571 1568 1572 CONECT 1572 1571 1573 CONECT 1573 1543 1572 1574 1575 CONECT 1574 1573 CONECT 1575 1573 CONECT 1576 1570 CONECT 1584 1615 CONECT 1598 1599 1604 1607 CONECT 1599 1598 1600 1605 CONECT 1600 1599 1601 CONECT 1601 1600 1602 1606 CONECT 1602 1601 1603 1604 CONECT 1603 1602 CONECT 1604 1598 1602 CONECT 1605 1599 CONECT 1606 1601 CONECT 1607 1598 1608 1611 CONECT 1608 1607 1609 CONECT 1609 1608 1610 1612 CONECT 1610 1609 1611 1613 CONECT 1611 1607 1610 CONECT 1612 1609 1618 CONECT 1613 1610 1614 CONECT 1614 1613 1615 CONECT 1615 1584 1614 1616 1617 CONECT 1616 1615 CONECT 1617 1615 CONECT 1618 1612 CONECT 1785 138 159 271 308 CONECT 1786 380 409 523 560 CONECT 1787 629 648 756 796 CONECT 1788 1789 1790 CONECT 1789 1788 CONECT 1790 1788 1791 1792 CONECT 1791 1790 CONECT 1792 1790 1793 CONECT 1793 1792 CONECT 1794 1795 1796 CONECT 1795 1794 CONECT 1796 1794 1797 1798 CONECT 1797 1796 CONECT 1798 1796 1799 CONECT 1799 1798 MASTER 480 0 9 3 8 0 6 6 1811 3 115 15 END
Display Options:
Goto PDB code:
3D presentation of molecule is powered by
3Dmol
, which supports all modern browsers and mobile devices via WebGL.
Hold mouse button:
left to rotate,middle to shift,right to zoom
Related entries of code: 4f6n
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
No similar entries are found!
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
4f6n
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Transcriptional regulator Kaiso zinc finger DNA binding domain
Ligand Name
methylated CpG site DNA, meECad
EC.Number
E.C.-.-.-.-
Resolution
2.8(Å)
Affinity (Kd/Ki/IC50)
Kd=190pM
Release Year
2012
Protein/NA Sequence
Check fasta file
Primary Reference
(2012) Proc.Natl.Acad.Sci.USA Vol. 109: pp. 15229-15234
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q86T24
Entrez Gene ID
NCBI Entrez Gene ID:
10009
ASD
Information of known allosteric effects of PDB entries
This site has been visited
times since Nov 2007.
Copyright ©2007-2024 涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃 缃戠珯澶囨鍙凤細
娌狪CP澶2021015625鍙-3
娌叕缃戝畨澶囷細
姝ｅ湪鐢宠涓
Technical Support锛堟妧鏈敮鎸侊級:
yingsaisi@foxmail.com
times since Nov 2007. 
娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓