Browse entries in the PDBbind-CN Database

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Related entries of code: 4f70
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3rgfRCSB PDB    PDBbind285aa, >3RGF_2|Chain... at 100%
4crlRCSB PDB    PDBbind285aa, >4CRL_2|Chain... at 100%
4f6sRCSB PDB    PDBbind287aa, >4F6S_2|Chain... *
4f6uRCSB PDB    PDBbind287aa, >4F6U_2|Chain... at 100%
4f6wRCSB PDB    PDBbind287aa, >4F6W_2|Chain... at 100%
4f7jRCSB PDB    PDBbind287aa, >4F7J_2|Chain... at 100%
4f7lRCSB PDB    PDBbind287aa, >4F7L_2|Chain... at 100%
4f7nRCSB PDB    PDBbind287aa, >4F7N_2|Chain... at 100%
5bnjRCSB PDB    PDBbind285aa, >5BNJ_2|Chain... at 100%
5ceiRCSB PDB    PDBbind287aa, >5CEI_2|Chain... at 100%
5fgkRCSB PDB    PDBbind266aa, >5FGK_2|Chain... at 100%
5hbeRCSB PDB    PDBbind266aa, >5HBE_2|Chain... at 100%
5hbhRCSB PDB    PDBbind270aa, >5HBH_2|Chain... at 99%
5hbjRCSB PDB    PDBbind270aa, >5HBJ_2|Chain... at 99%
5hvyRCSB PDB    PDBbind287aa, >5HVY_2|Chain... at 100%
5i5zRCSB PDB    PDBbind266aa, >5I5Z_2|Chain... at 100%
5icpRCSB PDB    PDBbind267aa, >5ICP_2|Chain... at 100%
5idnRCSB PDB    PDBbind267aa, >5IDN_2|Chain... at 100%
5idpRCSB PDB    PDBbind268aa, >5IDP_2|Chain... at 100%
5xqxRCSB PDB    PDBbind263aa, >5XQX_2|Chain... at 100%
5xs2RCSB PDB    PDBbind263aa, >5XS2_2|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4f70
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman CDK8/CYCC
Ligand Name0ST
EC.Number E.C.2.7.11.22
Resolution 3(Å)
Affinity (Kd/Ki/IC50)Kd=1.82uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) Proc.Natl.Acad.Sci.USA Vol. 110: pp. 8081-8086
Ligand Properties
Formula C21H32N5O2
Molecular Weight 386.511
Exact Mass 386.256
No. of atoms 60
No. of bonds 62
Polar Surface Area 72.62
LOGP Value 2.97      (Computed with XLOGP3)
3.55      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P24863  P49336  
Entrez Gene IDNCBI Entrez Gene ID: 892  1024  
ASDInformation of known allosteric effects of PDB entries
 
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