Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 4flj
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2g6pRCSB PDB    PDBbind304aa, >2G6P_1|Chain... at 100%
2nq6RCSB PDB    PDBbind329aa, >2NQ6_1|Chain... *
2nq7RCSB PDB    PDBbind329aa, >2NQ7_1|Chain... at 100%
4fliRCSB PDB    PDBbind326aa, >4FLI_1|Chain... at 93%
4flkRCSB PDB    PDBbind326aa, >4FLK_1|Chain... at 93%
4fllRCSB PDB    PDBbind326aa, >4FLL_1|Chain... at 93%
4ikrRCSB PDB    PDBbind329aa, >4IKR_1|Chain... at 100%
4iksRCSB PDB    PDBbind329aa, >4IKS_1|Chain... at 100%
4iktRCSB PDB    PDBbind329aa, >4IKT_1|Chain... at 100%
4ikuRCSB PDB    PDBbind329aa, >4IKU_1|Chain... at 100%
4u1bRCSB PDB    PDBbind306aa, >4U1B_1|Chain... at 99%
4u69RCSB PDB    PDBbind306aa, >4U69_1|Chain... at 99%
4u6cRCSB PDB    PDBbind306aa, >4U6C_1|Chain... at 99%
4u6eRCSB PDB    PDBbind306aa, >4U6E_1|Chain... at 99%
4u6wRCSB PDB    PDBbind306aa, >4U6W_1|Chain... at 99%
4u6zRCSB PDB    PDBbind306aa, >4U6Z_1|Chain... at 99%
4u70RCSB PDB    PDBbind306aa, >4U70_1|Chain... at 99%
4u71RCSB PDB    PDBbind306aa, >4U71_1|Chain... at 99%
4u73RCSB PDB    PDBbind306aa, >4U73_1|Chain... at 99%
5yr6RCSB PDB    PDBbind304aa, >5YR6_1|Chain... at 99%
5yr5RCSB PDB    PDBbind304aa, >5YR5_1|Chain... at 99%
5yr4RCSB PDB    PDBbind304aa, >5YR4_1|Chain... at 99%
5ykpRCSB PDB    PDBbind305aa, >5YKP_1|Chain... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3pkcRCSB PDB    PDBbindY08
Entry Information
PDB ID4flj
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMethionine aminopeptidase 1
Ligand NameY08
EC.Number E.C.3.4.11.18
Resolution 1.74(Å)
Affinity (Kd/Ki/IC50)IC50=7.45uM
Release Year2012
Protein/NA SequenceCheck fasta file
Primary Reference (2012) J.Med.Chem. Vol. 55: pp. 8021-8027
Ligand Properties
Formula C22H38N2O6
Molecular Weight 426.547
Exact Mass 426.273
No. of atoms 68
No. of bonds 69
Polar Surface Area 119.33
LOGP Value 0.46      (Computed with XLOGP3)
0.78      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 15
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P53582  
Entrez Gene IDNCBI Entrez Gene ID: 23173  
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2024    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com