Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 06-SEP-12 4GZN TITLE MOUSE ZFP57 ZINC FINGERS IN COMPLEX WITH METHYLATED DNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: DNA (5'-D(*TP*AP*TP*TP*GP*CP*(5CM)P*GP*CP*AP*G)-3'); COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: ZINC FINGER DOMAIN, UNP RESIDUES 137-195; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: DNA (5'-D(*AP*CP*TP*GP*(5CM)P*GP*GP*CP*AP*AP*T)-3'); COMPND 8 CHAIN: B; COMPND 9 ENGINEERED: YES; COMPND 10 MOL_ID: 3; COMPND 11 MOLECULE: ZINC FINGER PROTEIN 57; COMPND 12 CHAIN: C; COMPND 13 SYNONYM: ZFP-57; COMPND 14 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 SYNTHETIC: YES; SOURCE 3 OTHER_DETAILS: THE DNA SEQUENCE OCCURS NATURALLY IN MOUSE.; SOURCE 4 MOL_ID: 2; SOURCE 5 SYNTHETIC: YES; SOURCE 6 OTHER_DETAILS: THE DNA SEQUENCE OCCURS NATURALLY IN MOUSE.; SOURCE 7 MOL_ID: 3; SOURCE 8 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 9 ORGANISM_COMMON: MOUSE; SOURCE 10 ORGANISM_TAXID: 10090; SOURCE 11 GENE: ZFP57; SOURCE 12 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 13 EXPRESSION_SYSTEM_TAXID: 562 KEYWDS ZINC FINGER, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR Y.LIU,X.ZHANG,X.CHENG REVDAT 2 21-NOV-12 4GZN 1 JRNL REVDAT 1 17-OCT-12 4GZN 0 JRNL AUTH Y.LIU,H.TOH,H.SASAKI,X.ZHANG,X.CHENG JRNL TITL AN ATOMIC MODEL OF ZFP57 RECOGNITION OF CPG METHYLATION JRNL TITL 2 WITHIN A SPECIFIC DNA SEQUENCE. JRNL REF GENES DEV. V. 26 2374 2012 JRNL REFN ISSN 0890-9369 JRNL PMID 23059534 JRNL DOI 10.1101/GAD.202200.112 REMARK 2 REMARK 2 RESOLUTION. 0.99 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (PHENIX.REFINE: 1.6.4_486) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VICENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE- REMARK 3 : KUNSTLEVE,LI-WEI HUNG,ROBERT IMMORMINO, REMARK 3 : TOM IOERGER,AIRLIE MCCOY,ERIK MCKEE,NIGEL REMARK 3 : MORIARTY,REETAL PAI,RANDY READ,JANE REMARK 3 : RICHARDSON,DAVID RICHARDSON,TOD ROMO,JIM REMARK 3 : SACCHETTINI,NICHOLAS SAUTER,JACOB SMITH, REMARK 3 : LAURENT STORONI,TOM TERWILLIGER,PETER REMARK 3 : ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 0.99 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 19.68 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.020 REMARK 3 COMPLETENESS FOR RANGE (%) : 93.2 REMARK 3 NUMBER OF REFLECTIONS : 117899 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.132 REMARK 3 R VALUE (WORKING SET) : 0.131 REMARK 3 FREE R VALUE : 0.140 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.070 REMARK 3 FREE R VALUE TEST SET COUNT : 5979 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 19.6867 - 2.1325 1.00 11997 607 0.1521 0.1527 REMARK 3 2 2.1325 - 1.6929 1.00 12091 574 0.1270 0.1382 REMARK 3 3 1.6929 - 1.4790 1.00 11983 664 0.1070 0.1228 REMARK 3 4 1.4790 - 1.3438 1.00 11948 652 0.1032 0.1155 REMARK 3 5 1.3438 - 1.2475 1.00 11958 672 0.1047 0.1127 REMARK 3 6 1.2475 - 1.1740 0.99 11877 655 0.1031 0.1151 REMARK 3 7 1.1740 - 1.1152 0.99 11909 607 0.1045 0.1207 REMARK 3 8 1.1152 - 1.0666 0.97 11707 588 0.1279 0.1403 REMARK 3 9 1.0666 - 1.0256 0.85 10204 565 0.1970 0.1963 REMARK 3 10 1.0256 - 0.9902 0.52 6246 395 0.3251 0.3175 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 0.30 REMARK 3 SHRINKAGE RADIUS : 0.00 REMARK 3 K_SOL : 0.47 REMARK 3 B_SOL : 65.15 REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.070 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 10.960 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 7.20 REMARK 3 MEAN B VALUE (OVERALL, A**2) : 7.84 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 0.44320 REMARK 3 B22 (A**2) : -0.59500 REMARK 3 B33 (A**2) : 0.15190 REMARK 3 B12 (A**2) : -0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : -0.00000 REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.009 1203 REMARK 3 ANGLE : 1.799 1776 REMARK 3 CHIRALITY : 0.075 200 REMARK 3 PLANARITY : 0.010 137 REMARK 3 DIHEDRAL : 25.061 601 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 4GZN COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 24-SEP-12. REMARK 100 THE RCSB ID CODE IS RCSB074833. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 12-JAN-12 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 4.6 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 22-BM REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.000 REMARK 200 MONOCHROMATOR : SI 111 CHANNEL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : MARMOSAIC 225 MM CCD REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 802194 REMARK 200 RESOLUTION RANGE HIGH (A) : 0.990 REMARK 200 RESOLUTION RANGE LOW (A) : 48.600 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 94.4 REMARK 200 DATA REDUNDANCY : 12.900 REMARK 200 R MERGE (I) : 0.13300 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 16.1000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 0.99 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.03 REMARK 200 COMPLETENESS FOR SHELL (%) : 58.9 REMARK 200 DATA REDUNDANCY IN SHELL : 3.90 REMARK 200 R MERGE FOR SHELL (I) : 0.40400 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.800 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: SAD REMARK 200 SOFTWARE USED: PHENIX (PHENIX.AUTOSOL) REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 42.12 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.13 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 25% MPD, 15% PEG8000, 100MM CACL2 AND REMARK 280 100 MM ACETATE PH 4.6, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE REMARK 280 289K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 2 2 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -X,Y,-Z+1/2 REMARK 290 4555 X,-Y,-Z REMARK 290 5555 X+1/2,Y+1/2,Z REMARK 290 6555 -X+1/2,-Y+1/2,Z+1/2 REMARK 290 7555 -X+1/2,Y+1/2,-Z+1/2 REMARK 290 8555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 48.05950 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 48.05950 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 20.10900 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 30.32050 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 20.10900 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 30.32050 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 48.05950 REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 20.10900 REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 30.32050 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 48.05950 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 20.10900 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 30.32050 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5250 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 6700 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -35.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, B, A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ALA C 195 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 SER C 136 CB OG REMARK 470 GLU C 137 CG CD OE1 OE2 REMARK 470 LYS C 193 CG CD CE NZ REMARK 470 PRO C 194 O CB CG CD REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 DT A 3 O3' DT A 3 C3' -0.047 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DT A 3 O5' - C5' - C4' ANGL. DEV. = -8.2 DEGREES REMARK 500 DC A 9 O4' - C1' - N1 ANGL. DEV. = -5.0 DEGREES REMARK 500 DA A 10 O4' - C1' - N9 ANGL. DEV. = -4.4 DEGREES REMARK 500 DT B 3 O4' - C1' - N1 ANGL. DEV. = 2.1 DEGREES REMARK 500 DG B 7 O4' - C1' - N9 ANGL. DEV. = -4.7 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 HOH C 377 DISTANCE = 6.50 ANGSTROMS REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN C 204 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS C 162 NE2 REMARK 620 2 HIS C 158 NE2 94.4 REMARK 620 3 CYS C 145 SG 121.8 104.6 REMARK 620 4 CYS C 142 SG 107.5 105.4 118.8 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN C 203 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS C 190 NE2 REMARK 620 2 HIS C 186 NE2 107.9 REMARK 620 3 CYS C 173 SG 112.5 106.7 REMARK 620 4 CYS C 170 SG 108.9 105.9 114.5 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 CA B 101 CA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HOH B 208 O REMARK 620 2 HOH A 103 O 165.0 REMARK 620 3 HOH B 206 O 96.7 87.8 REMARK 620 4 HOH B 209 O 86.9 80.8 73.3 REMARK 620 5 HOH B 204 O 81.9 87.3 151.4 78.1 REMARK 620 6 HOH A 101 O 111.0 76.5 127.9 147.6 78.0 REMARK 620 7 HOH B 203 O 81.7 113.2 71.6 141.3 135.6 70.0 REMARK 620 N 1 2 3 4 5 6 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE CA B 101 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MPD C 201 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MPD C 202 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN C 203 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN C 204 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC6 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ACT C 205 DBREF 4GZN C 137 195 UNP Q8C6P8 ZFP57_MOUSE 137 195 DBREF 4GZN A 1 11 PDB 4GZN 4GZN 1 11 DBREF 4GZN B 1 11 PDB 4GZN 4GZN 1 11 SEQADV 4GZN SER C 136 UNP Q8C6P8 EXPRESSION TAG SEQRES 1 A 11 DT DA DT DT DG DC 5CM DG DC DA DG SEQRES 1 B 11 DA DC DT DG 5CM DG DG DC DA DA DT SEQRES 1 C 60 SER GLU ARG PRO PHE PHE CYS ASN PHE CYS GLY LYS THR SEQRES 2 C 60 TYR ARG ASP ALA SER GLY LEU SER ARG HIS ARG ARG ALA SEQRES 3 C 60 HIS LEU GLY TYR ARG PRO ARG SER CYS PRO GLU CYS GLY SEQRES 4 C 60 LYS CYS PHE ARG ASP GLN SER GLU VAL ASN ARG HIS LEU SEQRES 5 C 60 LYS VAL HIS GLN ASN LYS PRO ALA MODRES 4GZN 5CM A 7 DC MODRES 4GZN 5CM B 5 DC HET 5CM A 7 31 HET 5CM B 5 20 HET CA B 101 1 HET MPD C 201 8 HET MPD C 202 8 HET ZN C 203 1 HET ZN C 204 1 HET ACT C 205 4 HETNAM 5CM 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE HETNAM CA CALCIUM ION HETNAM MPD (4S)-2-METHYL-2,4-PENTANEDIOL HETNAM ZN ZINC ION HETNAM ACT ACETATE ION FORMUL 1 5CM 2(C10 H16 N3 O7 P) FORMUL 4 CA CA 2+ FORMUL 5 MPD 2(C6 H14 O2) FORMUL 7 ZN 2(ZN 2+) FORMUL 9 ACT C2 H3 O2 1- FORMUL 10 HOH *257(H2 O) HELIX 1 1 ASP C 151 GLY C 164 1 14 HELIX 2 2 ASP C 179 LEU C 187 1 9 HELIX 3 3 LYS C 188 GLN C 191 5 4 SHEET 1 A 2 PHE C 140 PHE C 141 0 SHEET 2 A 2 THR C 148 TYR C 149 -1 O TYR C 149 N PHE C 140 SHEET 1 B 2 ARG C 168 SER C 169 0 SHEET 2 B 2 CYS C 176 PHE C 177 -1 O PHE C 177 N ARG C 168 LINK O3'A DC A 6 P A5CM A 7 1555 1555 1.60 LINK O3'B DC A 6 P B5CM A 7 1555 1555 1.61 LINK O3'A5CM A 7 P A DG A 8 1555 1555 1.61 LINK O3'B5CM A 7 P B DG A 8 1555 1555 1.61 LINK O3' DG B 4 P 5CM B 5 1555 1555 1.61 LINK O3' 5CM B 5 P DG B 6 1555 1555 1.61 LINK NE2 HIS C 162 ZN ZN C 204 1555 1555 2.02 LINK NE2 HIS C 190 ZN ZN C 203 1555 1555 2.04 LINK NE2 HIS C 186 ZN ZN C 203 1555 1555 2.06 LINK NE2 HIS C 158 ZN ZN C 204 1555 1555 2.06 LINK SG CYS C 145 ZN ZN C 204 1555 1555 2.26 LINK SG CYS C 173 ZN ZN C 203 1555 1555 2.30 LINK SG CYS C 170 ZN ZN C 203 1555 1555 2.31 LINK SG CYS C 142 ZN ZN C 204 1555 1555 2.32 LINK CA CA B 101 O HOH B 208 1555 1555 2.37 LINK CA CA B 101 O HOH A 103 1555 1555 2.40 LINK CA CA B 101 O HOH B 206 1555 1555 2.41 LINK CA CA B 101 O HOH B 209 1555 1555 2.43 LINK CA CA B 101 O HOH B 204 1555 1555 2.43 LINK CA CA B 101 O HOH A 101 1555 1555 2.44 LINK CA CA B 101 O HOH B 203 1555 1555 2.46 SITE 1 AC1 7 HOH A 101 HOH A 103 HOH B 203 HOH B 204 SITE 2 AC1 7 HOH B 206 HOH B 208 HOH B 209 SITE 1 AC2 7 HOH A 168 PHE C 141 ASN C 184 HOH C 313 SITE 2 AC2 7 HOH C 328 HOH C 329 HOH C 377 SITE 1 AC3 7 5CM B 5 HOH B 265 HIS C 158 ALA C 161 SITE 2 AC3 7 HIS C 162 GLY C 164 HOH C 333 SITE 1 AC4 4 CYS C 170 CYS C 173 HIS C 186 HIS C 190 SITE 1 AC5 4 CYS C 142 CYS C 145 HIS C 158 HIS C 162 SITE 1 AC6 7 HOH A 111 LEU C 163 TYR C 165 HIS C 190 SITE 2 AC6 7 HOH C 337 HOH C 352 HOH C 392 CRYST1 40.218 60.641 96.119 90.00 90.00 90.00 C 2 2 21 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.024864 0.000000 0.000000 0.00000 SCALE2 0.000000 0.016490 0.000000 0.00000 SCALE3 0.000000 0.000000 0.010404 0.00000 ATOM 1 O5' DT A 1 -7.985 -30.025 11.405 1.00 17.47 O ANISOU 1 O5' DT A 1 2710 1858 2069 -169 415 -134 O ATOM 2 C5' DT A 1 -8.120 -30.528 12.719 1.00 16.89 C ANISOU 2 C5' DT A 1 2614 1778 2025 -118 490 -105 C ATOM 3 C4' DT A 1 -6.920 -30.172 13.579 1.00 16.26 C ANISOU 3 C4' DT A 1 2528 1675 1974 -104 544 -68 C ATOM 4 O4' DT A 1 -5.690 -30.592 12.933 1.00 16.25 O ANISOU 4 O4' DT A 1 2594 1582 2000 -2 546 -40 O ATOM 5 C3' DT A 1 -6.717 -28.689 13.837 1.00 15.70 C ANISOU 5 C3' DT A 1 2385 1688 1892 -93 570 -55 C ATOM 6 O3' DT A 1 -7.567 -28.288 14.899 1.00 15.42 O ANISOU 6 O3' DT A 1 2218 1836 1806 -159 559 -21 O ATOM 7 C2' DT A 1 -5.246 -28.676 14.237 1.00 15.66 C ANISOU 7 C2' DT A 1 2425 1611 1915 64 611 -39 C ATOM 8 C1' DT A 1 -4.651 -29.678 13.251 1.00 15.77 C ANISOU 8 C1' DT A 1 2476 1558 1956 96 595 14 C ATOM 9 N1 DT A 1 -4.137 -29.034 12.005 1.00 15.08 N ANISOU 9 N1 DT A 1 2367 1417 1946 355 621 63 N ATOM 10 C2 DT A 1 -2.985 -28.275 12.070 1.00 14.84 C ANISOU 10 C2 DT A 1 2300 1409 1928 494 597 147 C ATOM 11 O2 DT A 1 -2.351 -28.104 13.090 1.00 15.49 O ANISOU 11 O2 DT A 1 2399 1554 1932 539 553 229 O ATOM 12 N3 DT A 1 -2.591 -27.716 10.887 1.00 14.20 N ANISOU 12 N3 DT A 1 2193 1294 1908 597 638 128 N ATOM 13 C4 DT A 1 -3.218 -27.839 9.670 1.00 14.46 C ANISOU 13 C4 DT A 1 2225 1333 1935 556 633 46 C ATOM 14 O4 DT A 1 -2.780 -27.283 8.667 1.00 14.69 O ANISOU 14 O4 DT A 1 2267 1391 1925 521 626 59 O ATOM 15 C5 DT A 1 -4.420 -28.640 9.669 1.00 14.99 C ANISOU 15 C5 DT A 1 2369 1365 1962 502 605 -12 C ATOM 16 C7 DT A 1 -5.191 -28.831 8.397 1.00 15.50 C ANISOU 16 C7 DT A 1 2451 1458 1982 471 571 -55 C ATOM 17 C6 DT A 1 -4.820 -29.189 10.821 1.00 15.08 C ANISOU 17 C6 DT A 1 2393 1371 1966 488 603 -10 C ATOM 18 P DA A 2 -8.109 -26.780 14.981 1.00 14.46 P ANISOU 18 P DA A 2 1934 1844 1716 -79 520 -47 P ATOM 19 OP1 DA A 2 -9.057 -26.710 16.109 1.00 15.35 O ANISOU 19 OP1 DA A 2 2071 1991 1772 -133 552 -41 O ATOM 20 OP2 DA A 2 -8.564 -26.375 13.632 1.00 15.42 O ANISOU 20 OP2 DA A 2 2129 1966 1765 -96 389 -69 O ATOM 21 O5' DA A 2 -6.795 -25.928 15.304 1.00 13.32 O ANISOU 21 O5' DA A 2 1787 1668 1605 -39 366 58 O ATOM 22 C5' DA A 2 -6.169 -26.008 16.574 1.00 12.82 C ANISOU 22 C5' DA A 2 1756 1579 1537 153 263 106 C ATOM 23 C4' DA A 2 -4.956 -25.100 16.614 1.00 11.99 C ANISOU 23 C4' DA A 2 1675 1368 1512 324 172 87 C ATOM 24 O4' DA A 2 -4.039 -25.509 15.573 1.00 12.40 O ANISOU 24 O4' DA A 2 1764 1428 1521 227 166 169 O ATOM 25 C3' DA A 2 -5.209 -23.618 16.342 1.00 11.21 C ANISOU 25 C3' DA A 2 1506 1267 1488 393 113 70 C ATOM 26 O3' DA A 2 -5.536 -23.012 17.595 1.00 10.90 O ANISOU 26 O3' DA A 2 1461 1204 1478 456 -29 36 O ATOM 27 C2' DA A 2 -3.853 -23.158 15.825 1.00 11.56 C ANISOU 27 C2' DA A 2 1529 1335 1528 309 140 137 C ATOM 28 C1' DA A 2 -3.420 -24.360 15.027 1.00 11.70 C ANISOU 28 C1' DA A 2 1545 1381 1519 259 120 195 C ATOM 29 N9 DA A 2 -3.686 -24.355 13.603 1.00 11.19 N ANISOU 29 N9 DA A 2 1500 1267 1486 129 158 202 N ATOM 30 C8 DA A 2 -4.582 -25.115 12.906 1.00 11.16 C ANISOU 30 C8 DA A 2 1503 1258 1478 89 187 139 C ATOM 31 N7 DA A 2 -4.519 -24.933 11.610 1.00 10.44 N ANISOU 31 N7 DA A 2 1301 1208 1457 194 262 104 N ATOM 32 C5 DA A 2 -3.502 -24.010 11.465 1.00 10.20 C ANISOU 32 C5 DA A 2 1270 1174 1431 251 231 158 C ATOM 33 C6 DA A 2 -2.913 -23.414 10.337 1.00 10.11 C ANISOU 33 C6 DA A 2 1184 1246 1412 302 184 168 C ATOM 34 N6 DA A 2 -3.284 -23.678 9.078 1.00 11.52 N ANISOU 34 N6 DA A 2 1487 1444 1447 156 141 133 N ATOM 35 N1 DA A 2 -1.917 -22.536 10.552 1.00 10.09 N ANISOU 35 N1 DA A 2 1171 1230 1432 306 147 161 N ATOM 36 C2 DA A 2 -1.522 -22.265 11.799 1.00 10.71 C ANISOU 36 C2 DA A 2 1336 1275 1457 219 100 207 C ATOM 37 N3 DA A 2 -1.978 -22.781 12.927 1.00 11.18 N ANISOU 37 N3 DA A 2 1458 1317 1474 108 109 205 N ATOM 38 C4 DA A 2 -2.978 -23.644 12.682 1.00 10.66 C ANISOU 38 C4 DA A 2 1358 1236 1458 167 189 179 C ATOM 39 P DT A 3 -6.322 -21.613 17.672 1.00 11.18 P ANISOU 39 P DT A 3 1406 1276 1565 464 -132 -11 P ATOM 40 OP1 DT A 3 -6.476 -21.286 19.095 1.00 12.05 O ANISOU 40 OP1 DT A 3 1451 1492 1636 413 112 -31 O ATOM 41 OP2 DT A 3 -7.461 -21.665 16.728 1.00 12.26 O ANISOU 41 OP2 DT A 3 1574 1402 1681 476 -236 -33 O ATOM 42 O5' DT A 3 -5.309 -20.572 17.037 1.00 11.24 O ANISOU 42 O5' DT A 3 1552 1262 1457 272 22 48 O ATOM 43 C5' DT A 3 -4.086 -20.349 17.697 1.00 11.25 C ANISOU 43 C5' DT A 3 1614 1268 1391 265 132 14 C ATOM 44 C4'A DT A 3 -3.548 -19.193 16.928 0.49 11.69 C ANISOU 44 C4'A DT A 3 1854 1212 1374 269 96 14 C ATOM 45 C4'B DT A 3 -3.246 -19.265 17.032 0.51 11.18 C ANISOU 45 C4'B DT A 3 1578 1293 1376 292 205 36 C ATOM 46 O4'A DT A 3 -3.208 -19.691 15.619 0.49 12.89 O ANISOU 46 O4'A DT A 3 2176 1341 1379 208 148 63 O ATOM 47 O4'B DT A 3 -2.958 -19.628 15.652 0.51 12.17 O ANISOU 47 O4'B DT A 3 1841 1416 1366 261 244 84 O ATOM 48 C3'A DT A 3 -4.652 -18.147 16.764 0.49 11.16 C ANISOU 48 C3'A DT A 3 1739 1127 1375 197 19 -22 C ATOM 49 C3'B DT A 3 -3.876 -17.867 17.054 0.51 10.65 C ANISOU 49 C3'B DT A 3 1376 1284 1385 182 164 49 C ATOM 50 O3'A DT A 3 -4.091 -16.947 17.121 0.49 8.68 O ANISOU 50 O3'A DT A 3 1123 881 1294 100 6 -103 O ATOM 51 O3'B DT A 3 -2.869 -16.925 17.407 0.51 9.67 O ANISOU 51 O3'B DT A 3 1060 1241 1373 130 92 79 O ATOM 52 C2'A DT A 3 -4.914 -18.133 15.282 0.49 12.68 C ANISOU 52 C2'A DT A 3 2108 1303 1408 167 68 47 C ATOM 53 C2'B DT A 3 -4.380 -17.725 15.622 0.51 11.45 C ANISOU 53 C2'B DT A 3 1647 1331 1371 174 218 14 C ATOM 54 C1'A DT A 3 -3.593 -18.666 14.744 0.49 13.30 C ANISOU 54 C1'A DT A 3 2247 1421 1386 201 182 91 C ATOM 55 C1'B DT A 3 -3.426 -18.598 14.792 0.51 12.69 C ANISOU 55 C1'B DT A 3 1990 1465 1367 211 253 92 C ATOM 56 N1 DT A 3 -3.951 -19.262 13.500 1.00 13.17 N ANISOU 56 N1 DT A 3 2189 1465 1351 326 323 152 N ATOM 57 C2 DT A 3 -3.355 -18.914 12.306 1.00 13.07 C ANISOU 57 C2 DT A 3 2111 1506 1350 479 347 180 C ATOM 58 O2 DT A 3 -2.443 -18.109 12.222 1.00 14.45 O ANISOU 58 O2 DT A 3 2364 1685 1443 327 189 200 O ATOM 59 N3 DT A 3 -3.873 -19.564 11.208 1.00 12.51 N ANISOU 59 N3 DT A 3 1969 1463 1322 646 472 139 N ATOM 60 C4 DT A 3 -4.900 -20.492 11.173 1.00 12.02 C ANISOU 60 C4 DT A 3 1833 1437 1298 745 545 101 C ATOM 61 O4 DT A 3 -5.273 -21.011 10.119 1.00 12.47 O ANISOU 61 O4 DT A 3 1844 1572 1323 578 552 96 O ATOM 62 C5 DT A 3 -5.480 -20.794 12.458 1.00 12.56 C ANISOU 62 C5 DT A 3 2004 1431 1337 686 495 150 C ATOM 63 C7 DT A 3 -6.597 -21.784 12.549 1.00 13.08 C ANISOU 63 C7 DT A 3 2095 1497 1379 698 469 153 C ATOM 64 C6 DT A 3 -4.986 -20.171 13.536 1.00 12.49 C ANISOU 64 C6 DT A 3 2013 1409 1326 587 432 146 C ATOM 65 P A DT A 4 -4.956 -15.590 17.122 0.53 7.11 P ANISOU 65 P A DT A 4 745 755 1200 39 95 -32 P ATOM 66 P B DT A 4 -3.255 -15.434 17.880 0.47 8.41 P ANISOU 66 P B DT A 4 771 1100 1325 104 106 64 P ATOM 67 OP1A DT A 4 -4.862 -15.023 18.475 0.53 7.07 O ANISOU 67 OP1A DT A 4 813 677 1196 168 136 -33 O ATOM 68 OP1B DT A 4 -2.183 -14.962 18.791 0.47 9.35 O ANISOU 68 OP1B DT A 4 956 1235 1362 -19 -17 33 O ATOM 69 OP2A DT A 4 -6.239 -15.845 16.435 0.53 8.33 O ANISOU 69 OP2A DT A 4 1002 889 1275 43 95 -160 O ATOM 70 OP2B DT A 4 -4.665 -15.423 18.321 0.47 7.03 O ANISOU 70 OP2B DT A 4 576 791 1304 284 243 62 O ATOM 71 O5'A DT A 4 -4.176 -14.659 16.101 0.53 7.41 O ANISOU 71 O5'A DT A 4 667 952 1195 4 60 9 O ATOM 72 O5'B DT A 4 -3.178 -14.583 16.543 0.47 8.90 O ANISOU 72 O5'B DT A 4 912 1149 1320 101 162 78 O ATOM 73 C5'A DT A 4 -2.803 -14.400 16.274 0.53 7.66 C ANISOU 73 C5'A DT A 4 677 1015 1218 -32 123 9 C ATOM 74 C5'B DT A 4 -1.904 -14.337 16.026 0.47 8.92 C ANISOU 74 C5'B DT A 4 943 1139 1309 163 167 11 C ATOM 75 C4'A DT A 4 -2.329 -13.657 15.046 0.53 7.85 C ANISOU 75 C4'A DT A 4 742 1033 1209 -26 153 -27 C ATOM 76 C4'B DT A 4 -2.046 -13.606 14.721 0.47 8.59 C ANISOU 76 C4'B DT A 4 945 1050 1269 197 184 -40 C ATOM 77 O4'A DT A 4 -2.572 -14.474 13.868 0.53 8.35 O ANISOU 77 O4'A DT A 4 880 1086 1207 142 198 -48 O ATOM 78 O4'B DT A 4 -2.528 -14.510 13.703 0.47 8.72 O ANISOU 78 O4'B DT A 4 1007 1056 1251 318 225 -86 O ATOM 79 C3'A DT A 4 -3.040 -12.331 14.789 0.53 8.09 C ANISOU 79 C3'A DT A 4 828 1042 1206 -30 187 -29 C ATOM 80 C3'B DT A 4 -2.954 -12.369 14.745 0.47 8.54 C ANISOU 80 C3'B DT A 4 975 1032 1237 121 212 -44 C ATOM 81 O3'A DT A 4 -2.058 -11.464 14.238 0.53 9.00 O ANISOU 81 O3'A DT A 4 1048 1107 1264 -96 278 -25 O ATOM 82 O3'B DT A 4 -2.028 -11.463 14.212 0.47 9.15 O ANISOU 82 O3'B DT A 4 1114 1094 1267 -37 269 -33 O ATOM 83 C2'A DT A 4 -4.130 -12.727 13.800 0.53 8.61 C ANISOU 83 C2'A DT A 4 1025 1082 1165 133 118 -96 C ATOM 84 C2'B DT A 4 -4.096 -12.775 13.820 0.47 8.87 C ANISOU 84 C2'B DT A 4 1126 1049 1195 254 145 -101 C ATOM 85 C1'A DT A 4 -3.385 -13.749 12.954 0.53 8.71 C ANISOU 85 C1'A DT A 4 1067 1094 1147 173 166 -94 C ATOM 86 C1'B DT A 4 -3.386 -13.751 12.890 0.47 8.94 C ANISOU 86 C1'B DT A 4 1144 1075 1176 280 178 -112 C ATOM 87 N1 DT A 4 -4.233 -14.739 12.216 1.00 9.13 N ANISOU 87 N1 DT A 4 1202 1152 1115 252 134 -116 N ATOM 88 C2 DT A 4 -3.946 -15.010 10.896 1.00 9.01 C ANISOU 88 C2 DT A 4 1045 1285 1095 299 173 -148 C ATOM 89 O2 DT A 4 -3.052 -14.471 10.273 1.00 10.37 O ANISOU 89 O2 DT A 4 1324 1473 1144 219 266 -179 O ATOM 90 N3 DT A 4 -4.747 -15.942 10.312 1.00 8.78 N ANISOU 90 N3 DT A 4 884 1377 1074 307 150 -147 N ATOM 91 C4 DT A 4 -5.774 -16.626 10.905 1.00 8.99 C ANISOU 91 C4 DT A 4 901 1437 1077 289 122 -233 C ATOM 92 O4 DT A 4 -6.422 -17.444 10.271 1.00 9.60 O ANISOU 92 O4 DT A 4 911 1665 1071 94 178 -375 O ATOM 93 C5 DT A 4 -6.034 -16.310 12.292 1.00 8.98 C ANISOU 93 C5 DT A 4 1065 1270 1077 259 109 -200 C ATOM 94 C7 DT A 4 -7.151 -17.016 13.004 1.00 10.09 C ANISOU 94 C7 DT A 4 1362 1362 1110 96 81 -231 C ATOM 95 C6 DT A 4 -5.252 -15.396 12.879 1.00 9.17 C ANISOU 95 C6 DT A 4 1237 1152 1097 276 67 -147 C ATOM 96 P DG A 5 -2.340 -9.895 14.044 1.00 8.17 P ANISOU 96 P DG A 5 986 993 1126 -119 83 -58 P ATOM 97 OP1 DG A 5 -1.257 -9.148 14.711 1.00 10.94 O ANISOU 97 OP1 DG A 5 1468 1417 1271 -261 -68 -125 O ATOM 98 OP2 DG A 5 -3.766 -9.596 14.368 1.00 8.72 O ANISOU 98 OP2 DG A 5 1181 973 1161 141 115 -54 O ATOM 99 O5' DG A 5 -2.110 -9.665 12.495 1.00 10.01 O ANISOU 99 O5' DG A 5 1192 1404 1206 -112 211 5 O ATOM 100 C5'A DG A 5 -0.806 -9.691 11.928 0.52 9.98 C ANISOU 100 C5'A DG A 5 1153 1420 1218 -296 248 -20 C ATOM 101 C5'B DG A 5 -0.918 -10.232 11.925 0.48 10.31 C ANISOU 101 C5'B DG A 5 1196 1498 1222 -257 205 31 C ATOM 102 C4'A DG A 5 -0.911 -9.287 10.468 0.52 10.08 C ANISOU 102 C4'A DG A 5 1129 1467 1232 -412 237 -50 C ATOM 103 C4'B DG A 5 -0.797 -9.886 10.458 0.48 10.51 C ANISOU 103 C4'B DG A 5 1164 1583 1246 -318 183 23 C ATOM 104 O4'A DG A 5 -1.614 -10.328 9.749 0.52 10.20 O ANISOU 104 O4'A DG A 5 1113 1522 1242 -399 195 -119 O ATOM 105 O4'B DG A 5 -1.695 -10.686 9.654 0.48 10.68 O ANISOU 105 O4'B DG A 5 1148 1652 1257 -339 183 -36 O ATOM 106 C3'A DG A 5 -1.662 -7.988 10.193 0.52 10.15 C ANISOU 106 C3'A DG A 5 1126 1485 1245 -468 217 4 C ATOM 107 C3'B DG A 5 -1.179 -8.464 10.118 0.48 10.58 C ANISOU 107 C3'B DG A 5 1121 1632 1268 -387 132 104 C ATOM 108 O3'A DG A 5 -0.932 -7.332 9.169 0.52 10.71 O ANISOU 108 O3'A DG A 5 1250 1501 1319 -490 192 53 O ATOM 109 O3'B DG A 5 -0.436 -8.149 8.963 0.48 11.05 O ANISOU 109 O3'B DG A 5 1121 1714 1364 -498 101 180 O ATOM 110 C2'A DG A 5 -3.046 -8.441 9.734 0.52 10.06 C ANISOU 110 C2'A DG A 5 1099 1508 1216 -491 183 9 C ATOM 111 C2'B DG A 5 -2.683 -8.561 9.853 0.48 10.37 C ANISOU 111 C2'B DG A 5 1111 1607 1221 -358 118 78 C ATOM 112 C1'A DG A 5 -2.795 -9.829 9.147 0.52 9.95 C ANISOU 112 C1'A DG A 5 1084 1513 1183 -387 194 -22 C ATOM 113 C1'B DG A 5 -2.760 -9.897 9.129 0.48 10.17 C ANISOU 113 C1'B DG A 5 1093 1581 1190 -320 165 24 C ATOM 114 N9 DG A 5 -3.898 -10.770 9.370 1.00 9.03 N ANISOU 114 N9 DG A 5 920 1418 1092 -242 200 14 N ATOM 115 C8 DG A 5 -4.511 -11.045 10.573 1.00 8.49 C ANISOU 115 C8 DG A 5 869 1319 1037 -159 244 83 C ATOM 116 N7 DG A 5 -5.465 -11.923 10.478 1.00 8.01 N ANISOU 116 N7 DG A 5 855 1215 975 -78 246 86 N ATOM 117 C5 DG A 5 -5.482 -12.263 9.134 1.00 7.45 C ANISOU 117 C5 DG A 5 788 1089 954 9 275 70 C ATOM 118 C6 DG A 5 -6.300 -13.178 8.441 1.00 7.13 C ANISOU 118 C6 DG A 5 759 1002 948 44 249 58 C ATOM 119 O6 DG A 5 -7.195 -13.886 8.913 1.00 7.41 O ANISOU 119 O6 DG A 5 778 1057 980 5 235 50 O ATOM 120 N1 DG A 5 -6.011 -13.238 7.085 1.00 7.35 N ANISOU 120 N1 DG A 5 782 1052 957 88 270 25 N ATOM 121 C2 DG A 5 -5.031 -12.500 6.466 1.00 7.87 C ANISOU 121 C2 DG A 5 838 1179 972 82 300 20 C ATOM 122 N2 DG A 5 -4.895 -12.696 5.145 1.00 8.81 N ANISOU 122 N2 DG A 5 1076 1300 973 -27 327 -9 N ATOM 123 N3 DG A 5 -4.245 -11.643 7.109 1.00 8.38 N ANISOU 123 N3 DG A 5 903 1270 1011 -70 349 25 N ATOM 124 C4 DG A 5 -4.520 -11.571 8.436 1.00 8.06 C ANISOU 124 C4 DG A 5 808 1241 1014 -89 269 46 C ATOM 125 P A DC A 6 -1.402 -5.904 8.601 0.59 11.54 P ANISOU 125 P A DC A 6 1453 1523 1410 -577 162 112 P ATOM 126 P B DC A 6 -0.440 -6.654 8.386 0.41 12.10 P ANISOU 126 P B DC A 6 1293 1822 1483 -523 27 231 P ATOM 127 OP1A DC A 6 -0.218 -5.251 8.009 0.59 12.46 O ANISOU 127 OP1A DC A 6 1625 1617 1493 -585 86 118 O ATOM 128 OP1B DC A 6 0.765 -6.484 7.547 0.41 12.11 O ANISOU 128 OP1B DC A 6 1285 1832 1483 -583 -7 251 O ATOM 129 OP2A DC A 6 -2.176 -5.213 9.652 0.59 12.37 O ANISOU 129 OP2A DC A 6 1692 1564 1443 -563 96 103 O ATOM 130 OP2B DC A 6 -0.692 -5.728 9.513 0.41 12.67 O ANISOU 130 OP2B DC A 6 1414 1889 1512 -484 -48 210 O ATOM 131 O5'A DC A 6 -2.411 -6.283 7.425 0.59 11.07 O ANISOU 131 O5'A DC A 6 1279 1512 1417 -429 263 66 O ATOM 132 O5'B DC A 6 -1.735 -6.613 7.454 0.41 12.11 O ANISOU 132 O5'B DC A 6 1325 1752 1523 -471 80 223 O ATOM 133 C5'A DC A 6 -1.914 -7.033 6.330 0.59 11.35 C ANISOU 133 C5'A DC A 6 1264 1560 1491 -351 249 39 C ATOM 134 C5'B DC A 6 -1.737 -7.314 6.220 0.41 11.99 C ANISOU 134 C5'B DC A 6 1274 1709 1574 -403 109 198 C ATOM 135 C4'A DC A 6 -3.062 -7.382 5.413 0.59 11.78 C ANISOU 135 C4'A DC A 6 1298 1598 1579 -282 200 30 C ATOM 136 C4'B DC A 6 -3.112 -7.297 5.575 0.41 11.93 C ANISOU 136 C4'B DC A 6 1250 1651 1634 -323 99 182 C ATOM 137 O4'A DC A 6 -3.960 -8.283 6.102 0.59 11.49 O ANISOU 137 O4'A DC A 6 1180 1548 1636 -218 204 -3 O ATOM 138 O4'B DC A 6 -3.966 -8.274 6.209 0.41 11.54 O ANISOU 138 O4'B DC A 6 1147 1578 1659 -262 103 113 O ATOM 139 C3'A DC A 6 -3.888 -6.175 4.994 0.59 12.35 C ANISOU 139 C3'A DC A 6 1432 1634 1626 -248 121 54 C ATOM 140 C3'B DC A 6 -3.889 -5.986 5.659 0.41 12.25 C ANISOU 140 C3'B DC A 6 1332 1641 1681 -306 57 245 C ATOM 141 O3'A DC A 6 -3.866 -6.091 3.570 0.59 13.40 O ANISOU 141 O3'A DC A 6 1646 1756 1688 -264 108 171 O ATOM 142 O3'B DC A 6 -3.905 -5.390 4.372 0.41 12.93 O ANISOU 142 O3'B DC A 6 1459 1712 1740 -350 74 384 O ATOM 143 C2'A DC A 6 -5.278 -6.447 5.587 0.59 11.90 C ANISOU 143 C2'A DC A 6 1340 1549 1633 -165 105 7 C ATOM 144 C2'B DC A 6 -5.295 -6.398 6.095 0.41 11.80 C ANISOU 144 C2'B DC A 6 1237 1574 1671 -243 24 144 C ATOM 145 C1'A DC A 6 -5.285 -7.966 5.737 0.59 11.36 C ANISOU 145 C1'A DC A 6 1191 1484 1642 -136 113 -39 C ATOM 146 C1'B DC A 6 -5.279 -7.902 5.862 0.41 11.32 C ANISOU 146 C1'B DC A 6 1142 1503 1656 -179 51 44 C ATOM 147 N1 DC A 6 -6.169 -8.624 6.766 1.00 10.53 N ANISOU 147 N1 DC A 6 1034 1349 1619 -99 27 -121 N ATOM 148 C2 DC A 6 -7.036 -9.623 6.306 1.00 9.47 C ANISOU 148 C2 DC A 6 898 1151 1551 -44 -41 -148 C ATOM 149 O2 DC A 6 -7.076 -9.899 5.098 1.00 10.06 O ANISOU 149 O2 DC A 6 1020 1253 1550 -109 -27 -46 O ATOM 150 N3 DC A 6 -7.823 -10.261 7.204 1.00 8.86 N ANISOU 150 N3 DC A 6 786 1078 1502 70 -54 -199 N ATOM 151 C4 DC A 6 -7.754 -9.939 8.504 1.00 8.97 C ANISOU 151 C4 DC A 6 797 1100 1510 85 -3 -273 C ATOM 152 N4 DC A 6 -8.548 -10.591 9.356 1.00 8.93 N ANISOU 152 N4 DC A 6 818 1109 1466 103 57 -254 N ATOM 153 C5 DC A 6 -6.870 -8.930 8.993 1.00 9.86 C ANISOU 153 C5 DC A 6 922 1230 1593 34 -8 -292 C ATOM 154 C6 DC A 6 -6.098 -8.311 8.093 1.00 10.30 C ANISOU 154 C6 DC A 6 1049 1245 1618 -38 5 -258 C HETATM 155 N1 5CM A 7 -9.385 -6.947 5.241 1.00 13.58 N ANISOU 155 N1 5CM A 7 1468 1894 1796 -244 120 418 N HETATM 156 C2 5CM A 7 -10.325 -7.956 5.653 1.00 12.05 C ANISOU 156 C2 5CM A 7 1096 1706 1775 -187 129 450 C HETATM 157 N3 5CM A 7 -10.573 -8.091 7.068 1.00 10.67 N ANISOU 157 N3 5CM A 7 766 1486 1802 -23 3 287 N HETATM 158 C4 5CM A 7 -9.969 -7.314 7.948 1.00 10.89 C ANISOU 158 C4 5CM A 7 925 1366 1848 -35 -53 157 C HETATM 159 C5 5CM A 7 -9.007 -6.263 7.508 1.00 12.42 C ANISOU 159 C5 5CM A 7 1230 1603 1887 -132 -12 174 C HETATM 160 C5A 5CM A 7 -8.325 -5.387 8.495 1.00 13.22 C ANISOU 160 C5A 5CM A 7 1465 1617 1941 -214 -9 146 C HETATM 161 C6 5CM A 7 -8.771 -6.151 6.203 1.00 13.34 C ANISOU 161 C6 5CM A 7 1475 1742 1850 -169 6 304 C HETATM 162 O2 5CM A 7 -10.894 -8.684 4.861 1.00 12.77 O ANISOU 162 O2 5CM A 7 1149 1917 1787 -150 157 528 O HETATM 163 N4 5CM A 7 -10.226 -7.477 9.328 1.00 10.14 N ANISOU 163 N4 5CM A 7 836 1163 1854 -82 -172 -85 N HETATM 164 C1'A5CM A 7 -9.245 -7.015 3.798 0.62 14.73 C ANISOU 164 C1'A5CM A 7 1757 2059 1781 -190 115 333 C HETATM 165 C1'B5CM A 7 -9.232 -6.949 3.834 0.38 14.36 C ANISOU 165 C1'B5CM A 7 1720 1941 1794 -330 93 430 C HETATM 166 C2'A5CM A 7 -9.757 -5.848 3.014 0.62 14.86 C ANISOU 166 C2'A5CM A 7 1757 2122 1768 -102 111 294 C HETATM 167 C2'B5CM A 7 -9.943 -5.759 3.317 0.38 14.73 C ANISOU 167 C2'B5CM A 7 1815 1983 1800 -296 72 423 C HETATM 168 C3'A5CM A 7 -8.660 -5.504 2.078 0.62 15.06 C ANISOU 168 C3'A5CM A 7 1826 2135 1760 -124 97 288 C HETATM 169 C3'B5CM A 7 -8.929 -5.011 2.563 0.38 14.76 C ANISOU 169 C3'B5CM A 7 1849 1965 1795 -297 83 444 C HETATM 170 C4'A5CM A 7 -7.708 -6.622 2.237 0.62 15.07 C ANISOU 170 C4'A5CM A 7 1890 2065 1769 -217 91 298 C HETATM 171 C4'B5CM A 7 -7.742 -5.896 2.556 0.38 14.42 C ANISOU 171 C4'B5CM A 7 1817 1878 1783 -395 86 491 C HETATM 172 O4'A5CM A 7 -7.870 -7.113 3.530 0.62 15.18 O ANISOU 172 O4'A5CM A 7 1930 2060 1778 -267 130 335 O HETATM 173 O4'B5CM A 7 -7.863 -6.784 3.619 0.38 14.38 O ANISOU 173 O4'B5CM A 7 1811 1866 1785 -472 97 477 O HETATM 174 O3'A5CM A 7 -9.027 -5.437 0.744 0.62 15.57 O ANISOU 174 O3'A5CM A 7 1954 2216 1744 -43 94 305 O HETATM 175 O3'B5CM A 7 -9.380 -4.846 1.280 0.38 15.09 O ANISOU 175 O3'B5CM A 7 1932 2000 1800 -220 91 428 O HETATM 176 C5'A5CM A 7 -6.310 -6.194 1.931 0.62 14.81 C ANISOU 176 C5'A5CM A 7 1832 2018 1779 -245 48 285 C HETATM 177 C5'B5CM A 7 -6.450 -5.127 2.574 0.38 13.99 C ANISOU 177 C5'B5CM A 7 1709 1831 1777 -383 85 518 C HETATM 178 O5'A5CM A 7 -5.940 -5.085 2.661 0.62 14.34 O ANISOU 178 O5'A5CM A 7 1705 1955 1787 -287 15 297 O HETATM 179 O5'B5CM A 7 -6.167 -4.512 3.779 0.38 13.51 O ANISOU 179 O5'B5CM A 7 1557 1803 1774 -367 74 525 O HETATM 180 P A5CM A 7 -4.422 -4.783 2.826 0.62 14.21 P ANISOU 180 P A5CM A 7 1703 1891 1806 -328 62 297 P HETATM 181 P B5CM A 7 -4.713 -4.025 4.118 0.38 13.55 P ANISOU 181 P B5CM A 7 1562 1806 1779 -353 52 523 P HETATM 182 OP1A5CM A 7 -4.232 -3.510 3.613 0.62 14.42 O ANISOU 182 OP1A5CM A 7 1729 1932 1819 -327 -36 296 O HETATM 183 OP1B5CM A 7 -4.722 -3.089 5.297 0.38 14.17 O ANISOU 183 OP1B5CM A 7 1722 1839 1822 -298 20 497 O HETATM 184 OP2A5CM A 7 -3.785 -4.725 1.452 0.62 14.92 O ANISOU 184 OP2A5CM A 7 1834 1995 1840 -287 87 310 O HETATM 185 OP2B5CM A 7 -4.091 -3.382 2.901 0.38 13.74 O ANISOU 185 OP2B5CM A 7 1615 1831 1776 -346 54 530 O ATOM 186 P A DG A 8 -9.993 -4.260 0.216 0.54 15.89 P ANISOU 186 P A DG A 8 2040 2278 1721 -55 80 332 P ATOM 187 P B DG A 8 -10.356 -3.624 0.911 0.46 14.67 P ANISOU 187 P B DG A 8 1790 1993 1792 -240 155 442 P ATOM 188 OP1A DG A 8 -9.735 -4.074 -1.227 0.54 16.05 O ANISOU 188 OP1A DG A 8 2067 2296 1736 -80 107 363 O ATOM 189 OP1B DG A 8 -9.825 -2.974 -0.300 0.46 15.59 O ANISOU 189 OP1B DG A 8 1970 2113 1843 -254 165 401 O ATOM 190 OP2A DG A 8 -9.873 -3.114 1.143 0.54 16.21 O ANISOU 190 OP2A DG A 8 2111 2301 1749 4 12 312 O ATOM 191 OP2B DG A 8 -10.577 -2.834 2.136 0.46 15.11 O ANISOU 191 OP2B DG A 8 1895 2016 1832 -283 153 459 O ATOM 192 O5'A DG A 8 -11.453 -4.862 0.418 0.54 14.91 O ANISOU 192 O5'A DG A 8 1868 2173 1624 -18 180 285 O ATOM 193 O5'B DG A 8 -11.735 -4.339 0.540 0.46 14.22 O ANISOU 193 O5'B DG A 8 1723 2001 1678 -129 163 370 O ATOM 194 C5'A DG A 8 -11.822 -6.046 -0.250 0.54 13.85 C ANISOU 194 C5'A DG A 8 1729 2051 1482 25 159 288 C ATOM 195 C5'B DG A 8 -11.753 -5.633 -0.044 0.46 13.39 C ANISOU 195 C5'B DG A 8 1619 1954 1515 -64 135 334 C ATOM 196 C4'A DG A 8 -13.156 -6.498 0.304 0.54 12.73 C ANISOU 196 C4'A DG A 8 1581 1913 1342 87 98 315 C ATOM 197 C4'B DG A 8 -13.045 -6.346 0.324 0.46 12.58 C ANISOU 197 C4'B DG A 8 1534 1888 1356 49 94 328 C ATOM 198 O4' DG A 8 -13.006 -6.749 1.720 1.00 11.87 O ANISOU 198 O4' DG A 8 1423 1831 1258 154 96 308 O ATOM 199 C3' DG A 8 -14.312 -5.509 0.173 1.00 12.46 C ANISOU 199 C3' DG A 8 1584 1831 1320 48 37 348 C ATOM 200 O3' DG A 8 -15.348 -6.301 -0.387 1.00 12.60 O ANISOU 200 O3' DG A 8 1636 1840 1311 17 -103 345 O ATOM 201 C2' DG A 8 -14.589 -5.039 1.605 1.00 11.57 C ANISOU 201 C2' DG A 8 1468 1672 1256 88 11 349 C ATOM 202 C1' DG A 8 -14.123 -6.230 2.427 1.00 10.44 C ANISOU 202 C1' DG A 8 1212 1564 1190 39 44 278 C ATOM 203 N9 DG A 8 -13.661 -5.915 3.774 1.00 8.85 N ANISOU 203 N9 DG A 8 1020 1214 1128 -77 -23 165 N ATOM 204 C8 DG A 8 -12.761 -4.946 4.142 1.00 9.52 C ANISOU 204 C8 DG A 8 1172 1250 1197 -195 -21 110 C ATOM 205 N7 DG A 8 -12.528 -4.923 5.427 1.00 9.11 N ANISOU 205 N7 DG A 8 1095 1180 1185 -251 -6 85 N ATOM 206 C5 DG A 8 -13.312 -5.949 5.943 1.00 7.77 C ANISOU 206 C5 DG A 8 819 1033 1099 -130 -4 75 C ATOM 207 C6 DG A 8 -13.481 -6.400 7.276 1.00 6.94 C ANISOU 207 C6 DG A 8 662 942 1033 -82 -69 5 C ATOM 208 O6 DG A 8 -12.950 -5.983 8.311 1.00 7.53 O ANISOU 208 O6 DG A 8 804 1006 1051 -136 -108 -33 O ATOM 209 N1 DG A 8 -14.384 -7.458 7.359 1.00 6.73 N ANISOU 209 N1 DG A 8 707 878 973 -24 -93 -16 N ATOM 210 C2 DG A 8 -15.039 -8.007 6.280 1.00 7.04 C ANISOU 210 C2 DG A 8 809 900 967 11 -99 13 C ATOM 211 N2 DG A 8 -15.880 -9.020 6.525 1.00 7.45 N ANISOU 211 N2 DG A 8 928 948 954 -144 -113 30 N ATOM 212 N3 DG A 8 -14.872 -7.593 5.024 1.00 7.38 N ANISOU 212 N3 DG A 8 823 1000 980 -36 -78 66 N ATOM 213 C4 DG A 8 -14.005 -6.568 4.935 1.00 7.77 C ANISOU 213 C4 DG A 8 871 1030 1050 12 -44 110 C ATOM 214 P DC A 9 -16.794 -5.685 -0.698 1.00 12.37 P ANISOU 214 P DC A 9 1681 1728 1292 39 -195 398 P ATOM 215 OP1 DC A 9 -17.322 -6.359 -1.909 1.00 13.05 O ANISOU 215 OP1 DC A 9 1792 1890 1277 -27 -215 386 O ATOM 216 OP2 DC A 9 -16.714 -4.217 -0.617 1.00 12.82 O ANISOU 216 OP2 DC A 9 1617 1821 1434 119 -260 302 O ATOM 217 O5' DC A 9 -17.672 -6.143 0.539 1.00 11.60 O ANISOU 217 O5' DC A 9 1591 1574 1242 24 -136 219 O ATOM 218 C5' DC A 9 -17.975 -7.500 0.677 1.00 11.18 C ANISOU 218 C5' DC A 9 1541 1491 1216 -29 -108 57 C ATOM 219 C4'A DC A 9 -18.832 -7.739 1.886 0.49 10.29 C ANISOU 219 C4'A DC A 9 1306 1423 1183 1 -171 -16 C ATOM 220 C4'B DC A 9 -19.060 -7.586 1.750 0.51 10.59 C ANISOU 220 C4'B DC A 9 1356 1459 1209 -10 -211 8 C ATOM 221 O4'A DC A 9 -18.184 -7.339 3.113 0.49 9.22 O ANISOU 221 O4'A DC A 9 1094 1280 1127 71 -132 0 O ATOM 222 O4'B DC A 9 -18.403 -7.425 3.034 0.51 9.67 O ANISOU 222 O4'B DC A 9 1222 1306 1146 49 -209 15 O ATOM 223 C3'A DC A 9 -20.092 -6.915 1.807 0.49 10.23 C ANISOU 223 C3'A DC A 9 1183 1480 1223 4 -261 -91 C ATOM 224 C3'B DC A 9 -20.207 -6.556 1.706 0.51 10.75 C ANISOU 224 C3'B DC A 9 1229 1561 1294 22 -309 -16 C ATOM 225 O3'A DC A 9 -21.084 -7.850 2.081 0.49 10.76 O ANISOU 225 O3'A DC A 9 1129 1646 1315 58 -358 -184 O ATOM 226 O3'B DC A 9 -21.476 -7.252 1.752 0.51 11.84 O ANISOU 226 O3'B DC A 9 1231 1805 1464 69 -376 -69 O ATOM 227 C2'A DC A 9 -19.927 -5.843 2.891 0.49 9.52 C ANISOU 227 C2'A DC A 9 1062 1380 1174 88 -271 -47 C ATOM 228 C2'B DC A 9 -19.949 -5.678 2.937 0.51 9.97 C ANISOU 228 C2'B DC A 9 1133 1438 1216 82 -321 -6 C ATOM 229 C1'A DC A 9 -19.125 -6.630 3.906 0.49 8.81 C ANISOU 229 C1'A DC A 9 974 1257 1117 77 -191 6 C ATOM 230 C1'B DC A 9 -19.183 -6.601 3.879 0.51 9.18 C ANISOU 230 C1'B DC A 9 1060 1288 1138 58 -230 22 C ATOM 231 N1 DC A 9 -18.279 -5.899 4.842 1.00 8.07 N ANISOU 231 N1 DC A 9 854 1146 1066 47 -198 76 N ATOM 232 C2 DC A 9 -18.353 -6.205 6.206 1.00 7.61 C ANISOU 232 C2 DC A 9 792 1071 1028 37 -168 64 C ATOM 233 O2 DC A 9 -19.180 -7.042 6.597 1.00 8.46 O ANISOU 233 O2 DC A 9 950 1205 1060 -156 -129 20 O ATOM 234 N3 DC A 9 -17.517 -5.570 7.063 1.00 7.15 N ANISOU 234 N3 DC A 9 749 950 1016 92 -102 114 N ATOM 235 C4 DC A 9 -16.649 -4.672 6.597 1.00 7.29 C ANISOU 235 C4 DC A 9 728 990 1051 53 -118 161 C ATOM 236 N4 DC A 9 -15.840 -4.068 7.475 1.00 7.71 N ANISOU 236 N4 DC A 9 812 1037 1082 10 -119 152 N ATOM 237 C5 DC A 9 -16.564 -4.355 5.206 1.00 8.30 C ANISOU 237 C5 DC A 9 946 1131 1077 20 -123 174 C ATOM 238 C6 DC A 9 -17.380 -4.997 4.370 1.00 8.25 C ANISOU 238 C6 DC A 9 952 1125 1058 -13 -149 139 C ATOM 239 P A DA A 10 -22.604 -7.533 1.714 0.52 11.68 P ANISOU 239 P A DA A 10 1164 1857 1415 89 -426 -307 P ATOM 240 P B DA A 10 -22.870 -6.444 1.771 0.48 13.07 P ANISOU 240 P B DA A 10 1282 2038 1645 189 -423 -111 P ATOM 241 OP1A DA A 10 -23.301 -8.819 1.526 0.52 12.33 O ANISOU 241 OP1A DA A 10 1343 1902 1442 -48 -375 -408 O ATOM 242 OP1B DA A 10 -23.896 -7.306 1.151 0.48 13.15 O ANISOU 242 OP1B DA A 10 1253 2093 1651 182 -494 -158 O ATOM 243 OP2A DA A 10 -22.620 -6.542 0.616 0.52 12.54 O ANISOU 243 OP2A DA A 10 1378 1958 1431 205 -415 -219 O ATOM 244 OP2B DA A 10 -22.633 -5.096 1.213 0.48 13.60 O ANISOU 244 OP2B DA A 10 1375 2098 1696 249 -351 -40 O ATOM 245 O5'A DA A 10 -23.160 -6.828 3.021 0.52 12.06 O ANISOU 245 O5'A DA A 10 1064 1994 1523 175 -439 -358 O ATOM 246 O5'B DA A 10 -23.202 -6.315 3.322 0.48 13.71 O ANISOU 246 O5'B DA A 10 1364 2128 1719 190 -411 -197 O ATOM 247 C5'A DA A 10 -23.373 -7.668 4.130 0.52 13.07 C ANISOU 247 C5'A DA A 10 1189 2148 1628 276 -422 -368 C ATOM 248 C5'B DA A 10 -23.227 -7.495 4.104 0.48 14.53 C ANISOU 248 C5'B DA A 10 1515 2230 1777 287 -385 -270 C ATOM 249 C4'A DA A 10 -23.606 -6.868 5.386 0.52 14.15 C ANISOU 249 C4'A DA A 10 1319 2316 1740 481 -469 -365 C ATOM 250 C4'B DA A 10 -23.521 -7.125 5.535 0.48 15.55 C ANISOU 250 C4'B DA A 10 1702 2359 1846 472 -391 -325 C ATOM 251 O4'A DA A 10 -22.402 -6.167 5.744 0.52 14.56 O ANISOU 251 O4'A DA A 10 1425 2350 1756 593 -542 -400 O ATOM 252 O4'B DA A 10 -22.394 -6.373 6.047 0.48 15.76 O ANISOU 252 O4'B DA A 10 1759 2388 1843 603 -464 -393 O ATOM 253 C3'A DA A 10 -24.690 -5.807 5.281 0.52 15.30 C ANISOU 253 C3'A DA A 10 1544 2421 1847 527 -408 -342 C ATOM 254 C3'B DA A 10 -24.762 -6.257 5.687 0.48 16.41 C ANISOU 254 C3'B DA A 10 1886 2427 1920 508 -309 -316 C ATOM 255 O3'A DA A 10 -25.759 -6.316 6.034 0.52 16.30 O ANISOU 255 O3'A DA A 10 1726 2507 1958 437 -350 -322 O ATOM 256 O3'B DA A 10 -25.652 -6.927 6.606 0.48 17.28 O ANISOU 256 O3'B DA A 10 2069 2482 2014 392 -225 -281 O ATOM 257 C2'A DA A 10 -24.084 -4.568 5.938 0.52 15.53 C ANISOU 257 C2'A DA A 10 1640 2415 1844 604 -431 -376 C ATOM 258 C2'B DA A 10 -24.217 -4.887 6.141 0.48 16.39 C ANISOU 258 C2'B DA A 10 1918 2415 1894 596 -346 -359 C ATOM 259 C1'A DA A 10 -22.831 -5.138 6.594 0.52 15.43 C ANISOU 259 C1'A DA A 10 1686 2370 1807 687 -488 -421 C ATOM 260 C1'B DA A 10 -22.828 -5.200 6.713 0.48 16.11 C ANISOU 260 C1'B DA A 10 1889 2380 1853 690 -434 -413 C ATOM 261 N9 DA A 10 -21.707 -4.233 6.627 1.00 15.84 N ANISOU 261 N9 DA A 10 1899 2313 1805 843 -562 -477 N ATOM 262 C8 DA A 10 -21.199 -3.549 5.556 1.00 16.19 C ANISOU 262 C8 DA A 10 2023 2334 1796 923 -563 -505 C ATOM 263 N7 DA A 10 -20.158 -2.798 5.842 1.00 16.32 N ANISOU 263 N7 DA A 10 2103 2328 1767 1041 -584 -506 N ATOM 264 C5 DA A 10 -19.963 -3.018 7.197 1.00 15.43 C ANISOU 264 C5 DA A 10 1969 2171 1722 1174 -639 -534 C ATOM 265 C6 DA A 10 -19.022 -2.526 8.126 1.00 14.91 C ANISOU 265 C6 DA A 10 1928 2076 1661 1247 -676 -510 C ATOM 266 N6 DA A 10 -18.046 -1.663 7.823 1.00 15.24 N ANISOU 266 N6 DA A 10 1998 2174 1619 1251 -603 -447 N ATOM 267 N1 DA A 10 -19.122 -2.959 9.401 1.00 14.60 N ANISOU 267 N1 DA A 10 1887 1958 1703 1226 -713 -501 N ATOM 268 C2 DA A 10 -20.091 -3.819 9.731 1.00 14.56 C ANISOU 268 C2 DA A 10 1846 1938 1750 1207 -741 -529 C ATOM 269 N3 DA A 10 -21.033 -4.348 8.951 1.00 15.05 N ANISOU 269 N3 DA A 10 1938 2013 1769 1122 -725 -541 N ATOM 270 C4 DA A 10 -20.900 -3.905 7.692 1.00 15.25 C ANISOU 270 C4 DA A 10 1908 2131 1758 1102 -651 -541 C ATOM 271 P A DG A 11 -27.136 -5.506 6.143 0.51 16.95 P ANISOU 271 P A DG A 11 1849 2536 2054 338 -329 -315 P ATOM 272 P B DG A 11 -27.183 -6.457 6.754 0.49 17.96 P ANISOU 272 P B DG A 11 2179 2545 2101 248 -159 -284 P ATOM 273 OP1A DG A 11 -28.236 -6.491 6.113 0.51 17.10 O ANISOU 273 OP1A DG A 11 1888 2548 2061 236 -364 -321 O ATOM 274 OP1B DG A 11 -27.988 -7.638 7.139 0.49 18.54 O ANISOU 274 OP1B DG A 11 2351 2573 2120 257 -119 -276 O ATOM 275 OP2A DG A 11 -27.103 -4.402 5.157 0.51 17.38 O ANISOU 275 OP2A DG A 11 1970 2555 2078 346 -319 -289 O ATOM 276 OP2B DG A 11 -27.548 -5.697 5.535 0.49 18.46 O ANISOU 276 OP2B DG A 11 2303 2604 2105 230 -150 -294 O ATOM 277 O5'A DG A 11 -27.074 -4.854 7.593 0.51 16.67 O ANISOU 277 O5'A DG A 11 1851 2401 2082 160 -299 -354 O ATOM 278 O5'B DG A 11 -27.141 -5.475 8.014 0.49 17.56 O ANISOU 278 O5'B DG A 11 2110 2434 2130 155 -154 -312 O ATOM 279 C5'A DG A 11 -26.994 -5.705 8.714 0.51 16.39 C ANISOU 279 C5'A DG A 11 1856 2267 2103 53 -296 -397 C ATOM 280 C5'B DG A 11 -26.786 -6.030 9.273 0.49 17.21 C ANISOU 280 C5'B DG A 11 2075 2314 2150 56 -172 -357 C ATOM 281 C4'A DG A 11 -26.574 -4.878 9.905 0.51 16.27 C ANISOU 281 C4'A DG A 11 1879 2163 2140 2 -299 -429 C ATOM 282 C4'B DG A 11 -26.514 -4.931 10.279 0.49 16.82 C ANISOU 282 C4'B DG A 11 2008 2209 2175 8 -215 -401 C ATOM 283 O4'A DG A 11 -25.309 -4.252 9.594 0.51 15.78 O ANISOU 283 O4'A DG A 11 1782 2066 2148 -12 -334 -450 O ATOM 284 O4'B DG A 11 -25.220 -4.336 9.997 0.49 16.20 O ANISOU 284 O4'B DG A 11 1866 2115 2174 -29 -271 -435 O ATOM 285 C3'A DG A 11 -27.538 -3.745 10.247 0.51 16.77 C ANISOU 285 C3'A DG A 11 2023 2179 2171 0 -275 -421 C ATOM 286 C3'B DG A 11 -27.536 -3.796 10.251 0.49 17.07 C ANISOU 286 C3'B DG A 11 2085 2207 2196 10 -211 -402 C ATOM 287 O3'A DG A 11 -27.852 -3.793 11.633 0.51 17.32 O ANISOU 287 O3'A DG A 11 2144 2237 2200 -28 -225 -397 O ATOM 288 O3'B DG A 11 -27.989 -3.493 11.566 0.49 17.51 O ANISOU 288 O3'B DG A 11 2177 2252 2222 -14 -156 -385 O ATOM 289 C2'A DG A 11 -26.762 -2.481 9.887 0.51 16.44 C ANISOU 289 C2'A DG A 11 1960 2121 2164 -2 -308 -435 C ATOM 290 C2'B DG A 11 -26.756 -2.633 9.646 0.49 16.66 C ANISOU 290 C2'B DG A 11 2001 2146 2182 6 -265 -421 C ATOM 291 C1'A DG A 11 -25.341 -2.963 10.146 0.51 15.74 C ANISOU 291 C1'A DG A 11 1813 2023 2146 -2 -364 -454 C ATOM 292 C1'B DG A 11 -25.356 -2.946 10.165 0.49 15.94 C ANISOU 292 C1'B DG A 11 1852 2045 2160 -2 -329 -444 C ATOM 293 N9 DG A 11 -24.305 -2.192 9.485 1.00 14.87 N ANISOU 293 N9 DG A 11 1638 1884 2126 61 -442 -459 N ATOM 294 C8 DG A 11 -24.220 -1.854 8.159 1.00 15.14 C ANISOU 294 C8 DG A 11 1783 1861 2108 113 -477 -485 C ATOM 295 N7 DG A 11 -23.163 -1.148 7.868 1.00 14.35 N ANISOU 295 N7 DG A 11 1608 1790 2055 245 -586 -486 N ATOM 296 C5 DG A 11 -22.508 -1.018 9.084 1.00 13.19 C ANISOU 296 C5 DG A 11 1385 1612 2013 324 -554 -541 C ATOM 297 C6 DG A 11 -21.311 -0.351 9.420 1.00 12.38 C ANISOU 297 C6 DG A 11 1257 1478 1969 480 -467 -555 C ATOM 298 O6 DG A 11 -20.551 0.279 8.679 1.00 13.15 O ANISOU 298 O6 DG A 11 1488 1565 1943 430 -465 -499 O ATOM 299 N1 DG A 11 -21.004 -0.467 10.777 1.00 11.54 N ANISOU 299 N1 DG A 11 1028 1395 1961 405 -499 -565 N ATOM 300 C2 DG A 11 -21.775 -1.137 11.696 1.00 11.73 C ANISOU 300 C2 DG A 11 1029 1427 2001 187 -496 -507 C ATOM 301 N2 DG A 11 -21.361 -1.164 12.969 1.00 12.15 N ANISOU 301 N2 DG A 11 1146 1459 2012 96 -468 -408 N ATOM 302 N3 DG A 11 -22.898 -1.759 11.394 1.00 12.50 N ANISOU 302 N3 DG A 11 1148 1558 2042 162 -520 -491 N ATOM 303 C4 DG A 11 -23.197 -1.655 10.083 1.00 13.19 C ANISOU 303 C4 DG A 11 1321 1632 2059 160 -539 -523 C TER 304 DG A 11 ATOM 305 O5' DA B 1 -16.371 8.634 11.463 1.00 17.59 O ANISOU 305 O5' DA B 1 2312 1917 2453 115 -511 544 O ATOM 306 C5' DA B 1 -16.863 9.428 12.531 1.00 16.64 C ANISOU 306 C5' DA B 1 2199 1729 2396 255 -525 558 C ATOM 307 C4'A DA B 1 -17.429 8.526 13.590 0.51 16.01 C ANISOU 307 C4'A DA B 1 2103 1623 2357 397 -536 561 C ATOM 308 C4'B DA B 1 -17.507 8.606 13.659 0.49 16.04 C ANISOU 308 C4'B DA B 1 2113 1628 2352 390 -533 563 C ATOM 309 O4'A DA B 1 -18.615 7.853 13.102 0.51 15.37 O ANISOU 309 O4'A DA B 1 1965 1542 2332 511 -453 550 O ATOM 310 O4'B DA B 1 -18.664 7.880 13.149 0.49 15.37 O ANISOU 310 O4'B DA B 1 1962 1547 2329 509 -452 552 O ATOM 311 C3'A DA B 1 -16.431 7.455 13.981 0.51 15.93 C ANISOU 311 C3'A DA B 1 2156 1570 2327 414 -590 557 C ATOM 312 C3'B DA B 1 -16.655 7.552 14.381 0.49 16.00 C ANISOU 312 C3'B DA B 1 2193 1573 2312 425 -574 550 C ATOM 313 O3'A DA B 1 -16.378 7.480 15.377 0.51 15.85 O ANISOU 313 O3'A DA B 1 2228 1499 2297 319 -727 508 O ATOM 314 O3'B DA B 1 -16.995 7.448 15.800 0.49 16.24 O ANISOU 314 O3'B DA B 1 2401 1506 2261 427 -714 477 O ATOM 315 C2'A DA B 1 -17.026 6.158 13.448 0.51 15.42 C ANISOU 315 C2'A DA B 1 1986 1564 2308 472 -482 564 C ATOM 316 C2'B DA B 1 -17.019 6.293 13.587 0.49 15.39 C ANISOU 316 C2'B DA B 1 1988 1558 2299 468 -475 563 C ATOM 317 C1'A DA B 1 -18.510 6.471 13.348 0.51 14.82 C ANISOU 317 C1'A DA B 1 1833 1520 2276 547 -370 555 C ATOM 318 C1'B DA B 1 -18.516 6.488 13.366 0.49 14.80 C ANISOU 318 C1'B DA B 1 1832 1519 2273 544 -368 555 C ATOM 319 N9 DA B 1 -19.128 5.790 12.223 1.00 13.96 N ANISOU 319 N9 DA B 1 1606 1515 2182 605 -139 535 N ATOM 320 C8 DA B 1 -20.156 4.889 12.273 1.00 13.40 C ANISOU 320 C8 DA B 1 1488 1502 2099 585 40 491 C ATOM 321 N7 DA B 1 -20.517 4.427 11.099 1.00 12.98 N ANISOU 321 N7 DA B 1 1416 1481 2034 624 220 501 N ATOM 322 C5 DA B 1 -19.670 5.070 10.216 1.00 13.04 C ANISOU 322 C5 DA B 1 1397 1535 2022 648 265 545 C ATOM 323 C6 DA B 1 -19.547 5.007 8.812 1.00 13.40 C ANISOU 323 C6 DA B 1 1500 1604 1989 569 399 544 C ATOM 324 N6 DA B 1 -20.320 4.235 8.045 1.00 13.63 N ANISOU 324 N6 DA B 1 1539 1668 1971 596 430 495 N ATOM 325 N1 DA B 1 -18.598 5.767 8.229 1.00 13.88 N ANISOU 325 N1 DA B 1 1564 1693 2016 490 402 554 N ATOM 326 C2 DA B 1 -17.831 6.542 9.005 1.00 13.80 C ANISOU 326 C2 DA B 1 1437 1744 2062 497 300 591 C ATOM 327 N3 DA B 1 -17.857 6.690 10.329 1.00 13.70 N ANISOU 327 N3 DA B 1 1402 1717 2087 579 162 594 N ATOM 328 C4 DA B 1 -18.807 5.918 10.884 1.00 13.33 C ANISOU 328 C4 DA B 1 1397 1574 2093 678 106 554 C ATOM 329 P A DC B 2 -15.187 6.744 16.152 0.54 15.37 P ANISOU 329 P A DC B 2 2185 1417 2240 232 -797 493 P ATOM 330 P B DC B 2 -15.909 6.918 16.871 0.46 15.97 P ANISOU 330 P B DC B 2 2491 1400 2178 366 -851 399 P ATOM 331 OP1A DC B 2 -15.146 7.286 17.526 0.54 16.70 O ANISOU 331 OP1A DC B 2 2620 1453 2270 310 -877 523 O ATOM 332 OP1B DC B 2 -16.406 7.245 18.229 0.46 17.12 O ANISOU 332 OP1B DC B 2 2762 1515 2229 338 -874 417 O ATOM 333 OP2A DC B 2 -13.977 6.788 15.296 0.54 16.67 O ANISOU 333 OP2A DC B 2 2596 1474 2265 213 -828 505 O ATOM 334 OP2B DC B 2 -14.575 7.395 16.448 0.46 16.69 O ANISOU 334 OP2B DC B 2 2734 1413 2196 346 -922 409 O ATOM 335 O5'A DC B 2 -15.650 5.219 16.183 0.54 13.90 O ANISOU 335 O5'A DC B 2 1909 1287 2085 261 -752 367 O ATOM 336 O5'B DC B 2 -15.951 5.333 16.692 0.46 14.05 O ANISOU 336 O5'B DC B 2 1995 1294 2048 302 -771 288 O ATOM 337 C5'A DC B 2 -16.706 4.821 17.021 0.54 12.61 C ANISOU 337 C5'A DC B 2 1640 1231 1920 255 -614 207 C ATOM 338 C5'B DC B 2 -17.000 4.635 17.327 0.46 12.53 C ANISOU 338 C5'B DC B 2 1604 1251 1906 227 -607 165 C ATOM 339 C4'A DC B 2 -17.014 3.362 16.754 0.54 10.91 C ANISOU 339 C4'A DC B 2 1216 1186 1743 191 -478 61 C ATOM 340 C4'B DC B 2 -17.110 3.224 16.792 0.46 10.92 C ANISOU 340 C4'B DC B 2 1195 1211 1741 157 -469 54 C ATOM 341 O4'A DC B 2 -17.613 3.201 15.448 0.54 10.50 O ANISOU 341 O4'A DC B 2 1045 1245 1701 201 -406 -17 O ATOM 342 O4'B DC B 2 -17.569 3.208 15.427 0.46 10.57 O ANISOU 342 O4'B DC B 2 1069 1244 1704 184 -394 -6 O ATOM 343 C3'A DC B 2 -15.808 2.410 16.807 0.54 9.92 C ANISOU 343 C3'A DC B 2 1054 1106 1608 81 -333 26 C ATOM 344 C3'B DC B 2 -15.829 2.383 16.809 0.46 9.93 C ANISOU 344 C3'B DC B 2 1049 1114 1609 70 -337 20 C ATOM 345 O3'A DC B 2 -16.021 1.680 18.013 0.54 9.25 O ANISOU 345 O3'A DC B 2 1008 1043 1463 83 -177 -18 O ATOM 346 O3'B DC B 2 -16.018 1.678 18.018 0.46 9.18 O ANISOU 346 O3'B DC B 2 990 1036 1462 69 -193 -20 O ATOM 347 C2'A DC B 2 -15.891 1.611 15.503 0.54 10.23 C ANISOU 347 C2'A DC B 2 1105 1151 1629 131 -308 12 C ATOM 348 C2'B DC B 2 -15.910 1.566 15.516 0.46 10.23 C ANISOU 348 C2'B DC B 2 1093 1162 1631 112 -311 7 C ATOM 349 C1'A DC B 2 -17.298 1.898 14.996 0.54 10.31 C ANISOU 349 C1'A DC B 2 1067 1193 1657 54 -317 -15 C ATOM 350 C1'B DC B 2 -17.302 1.894 14.987 0.46 10.30 C ANISOU 350 C1'B DC B 2 1062 1192 1660 62 -315 -12 C ATOM 351 N1 DC B 2 -17.499 1.894 13.522 1.00 9.93 N ANISOU 351 N1 DC B 2 969 1157 1645 32 -240 -45 N ATOM 352 C2 DC B 2 -18.471 1.060 12.989 1.00 9.57 C ANISOU 352 C2 DC B 2 856 1160 1621 102 -292 -88 C ATOM 353 O2 DC B 2 -19.098 0.332 13.761 1.00 10.39 O ANISOU 353 O2 DC B 2 1025 1276 1648 -60 -342 -33 O ATOM 354 N3 DC B 2 -18.693 1.067 11.654 1.00 9.70 N ANISOU 354 N3 DC B 2 957 1134 1594 245 -192 -122 N ATOM 355 C4 DC B 2 -17.975 1.873 10.875 1.00 10.30 C ANISOU 355 C4 DC B 2 1130 1160 1623 329 -114 -91 C ATOM 356 N4 DC B 2 -18.226 1.848 9.562 1.00 11.21 N ANISOU 356 N4 DC B 2 1394 1233 1634 378 -21 -83 N ATOM 357 C5 DC B 2 -16.974 2.738 11.405 1.00 10.56 C ANISOU 357 C5 DC B 2 1113 1241 1657 143 -68 -19 C ATOM 358 C6 DC B 2 -16.773 2.721 12.724 1.00 10.38 C ANISOU 358 C6 DC B 2 1061 1224 1659 43 -133 11 C ATOM 359 P DT B 3 -15.030 0.491 18.482 1.00 7.79 P ANISOU 359 P DT B 3 781 887 1294 -47 -156 -53 P ATOM 360 OP1 DT B 3 -15.129 0.407 19.965 1.00 10.33 O ANISOU 360 OP1 DT B 3 1370 1264 1292 -70 -43 -49 O ATOM 361 OP2 DT B 3 -13.683 0.689 17.896 1.00 8.21 O ANISOU 361 OP2 DT B 3 862 950 1308 -129 -161 -173 O ATOM 362 O5' DT B 3 -15.650 -0.810 17.828 1.00 8.52 O ANISOU 362 O5' DT B 3 874 970 1393 -103 -78 -170 O ATOM 363 C5' DT B 3 -16.966 -1.228 18.164 1.00 8.84 C ANISOU 363 C5' DT B 3 888 1111 1359 -204 -121 -74 C ATOM 364 C4' DT B 3 -17.325 -2.381 17.253 1.00 8.58 C ANISOU 364 C4' DT B 3 940 1050 1271 -180 -193 26 C ATOM 365 O4' DT B 3 -17.497 -1.893 15.899 1.00 8.15 O ANISOU 365 O4' DT B 3 891 930 1275 -70 -174 16 O ATOM 366 C3' DT B 3 -16.269 -3.493 17.180 1.00 8.36 C ANISOU 366 C3' DT B 3 1051 922 1205 -193 -240 68 C ATOM 367 O3' DT B 3 -16.889 -4.753 17.184 1.00 8.93 O ANISOU 367 O3' DT B 3 1298 967 1126 -297 -255 102 O ATOM 368 C2' DT B 3 -15.664 -3.304 15.794 1.00 8.31 C ANISOU 368 C2' DT B 3 1039 917 1202 -144 -256 66 C ATOM 369 C1' DT B 3 -16.924 -2.869 15.057 1.00 8.09 C ANISOU 369 C1' DT B 3 1006 851 1217 -93 -200 34 C ATOM 370 N1 DT B 3 -16.717 -2.324 13.707 1.00 7.96 N ANISOU 370 N1 DT B 3 983 831 1210 39 -191 72 N ATOM 371 C2 DT B 3 -17.631 -2.681 12.732 1.00 8.35 C ANISOU 371 C2 DT B 3 1013 914 1244 190 -182 56 C ATOM 372 O2 DT B 3 -18.590 -3.397 12.941 1.00 9.04 O ANISOU 372 O2 DT B 3 1059 1057 1317 127 -282 47 O ATOM 373 N3 DT B 3 -17.392 -2.146 11.504 1.00 8.89 N ANISOU 373 N3 DT B 3 1203 962 1214 392 -83 89 N ATOM 374 C4 DT B 3 -16.355 -1.321 11.143 1.00 9.34 C ANISOU 374 C4 DT B 3 1319 1013 1216 415 69 128 C ATOM 375 O4 DT B 3 -16.238 -0.926 9.994 1.00 10.51 O ANISOU 375 O4 DT B 3 1534 1240 1218 475 58 144 O ATOM 376 C5 DT B 3 -15.441 -0.972 12.208 1.00 9.13 C ANISOU 376 C5 DT B 3 1319 910 1241 251 62 75 C ATOM 377 C7 DT B 3 -14.272 -0.082 11.924 1.00 9.84 C ANISOU 377 C7 DT B 3 1445 1004 1288 90 99 39 C ATOM 378 C6 DT B 3 -15.658 -1.483 13.431 1.00 8.43 C ANISOU 378 C6 DT B 3 1152 815 1235 47 -41 52 C ATOM 379 P DG B 4 -16.849 -5.690 18.484 1.00 9.13 P ANISOU 379 P DG B 4 1424 950 1094 -125 -304 23 P ATOM 380 OP1 DG B 4 -17.475 -4.946 19.605 1.00 11.59 O ANISOU 380 OP1 DG B 4 1970 1290 1142 -172 -34 -121 O ATOM 381 OP2 DG B 4 -15.467 -6.191 18.653 1.00 11.19 O ANISOU 381 OP2 DG B 4 1609 1318 1325 -165 -315 39 O ATOM 382 O5' DG B 4 -17.749 -6.907 18.002 1.00 8.73 O ANISOU 382 O5' DG B 4 1289 887 1140 -95 -82 -87 O ATOM 383 C5' DG B 4 -19.163 -6.750 17.863 1.00 8.30 C ANISOU 383 C5' DG B 4 1152 874 1128 -52 130 -100 C ATOM 384 C4' DG B 4 -19.648 -7.632 16.726 1.00 7.58 C ANISOU 384 C4' DG B 4 1002 787 1091 -15 181 -84 C ATOM 385 O4' DG B 4 -19.341 -6.999 15.457 1.00 7.54 O ANISOU 385 O4' DG B 4 992 815 1059 50 197 -52 O ATOM 386 C3' DG B 4 -19.002 -9.021 16.674 1.00 7.34 C ANISOU 386 C3' DG B 4 923 775 1090 -68 184 -82 C ATOM 387 O3' DG B 4 -20.053 -9.944 16.382 1.00 7.14 O ANISOU 387 O3' DG B 4 836 779 1097 -130 170 -39 O ATOM 388 C2' DG B 4 -17.997 -8.897 15.532 1.00 6.97 C ANISOU 388 C2' DG B 4 833 750 1065 -71 184 -84 C ATOM 389 C1' DG B 4 -18.703 -7.939 14.600 1.00 6.81 C ANISOU 389 C1' DG B 4 796 772 1019 -44 221 -73 C ATOM 390 N9 DG B 4 -17.820 -7.164 13.734 1.00 6.49 N ANISOU 390 N9 DG B 4 717 744 1004 -84 133 -102 N ATOM 391 C8 DG B 4 -16.722 -6.438 14.120 1.00 6.66 C ANISOU 391 C8 DG B 4 814 734 983 -110 88 -121 C ATOM 392 N7 DG B 4 -16.141 -5.802 13.137 1.00 6.52 N ANISOU 392 N7 DG B 4 756 755 967 -123 5 -118 N ATOM 393 C5 DG B 4 -16.919 -6.128 12.031 1.00 6.10 C ANISOU 393 C5 DG B 4 670 666 981 -49 -1 -88 C ATOM 394 C6 DG B 4 -16.779 -5.729 10.684 1.00 5.97 C ANISOU 394 C6 DG B 4 626 662 982 -45 -19 -55 C ATOM 395 O6 DG B 4 -15.918 -4.985 10.195 1.00 6.57 O ANISOU 395 O6 DG B 4 746 765 984 -86 -54 -37 O ATOM 396 N1 DG B 4 -17.765 -6.282 9.863 1.00 6.19 N ANISOU 396 N1 DG B 4 643 694 1014 -21 -32 -50 N ATOM 397 C2 DG B 4 -18.773 -7.099 10.303 1.00 6.24 C ANISOU 397 C2 DG B 4 550 771 1049 37 -29 -38 C ATOM 398 N2 DG B 4 -19.639 -7.531 9.370 1.00 7.02 N ANISOU 398 N2 DG B 4 622 962 1084 -98 -80 -45 N ATOM 399 N3 DG B 4 -18.924 -7.461 11.574 1.00 6.20 N ANISOU 399 N3 DG B 4 598 721 1038 -6 7 -77 N ATOM 400 C4 DG B 4 -17.958 -6.956 12.378 1.00 5.99 C ANISOU 400 C4 DG B 4 596 675 1005 5 72 -84 C HETATM 401 N1 5CM B 5 -16.392 -9.892 11.370 1.00 6.15 N ANISOU 401 N1 5CM B 5 651 747 940 22 33 -122 N HETATM 402 C2 5CM B 5 -16.075 -9.314 10.116 1.00 6.18 C ANISOU 402 C2 5CM B 5 613 810 926 4 -67 -95 C HETATM 403 N3 5CM B 5 -14.984 -8.420 10.054 1.00 6.29 N ANISOU 403 N3 5CM B 5 660 804 925 50 -100 -105 N HETATM 404 C4 5CM B 5 -14.299 -8.152 11.141 1.00 6.10 C ANISOU 404 C4 5CM B 5 685 694 939 76 -51 -103 C HETATM 405 C5 5CM B 5 -14.594 -8.781 12.446 1.00 6.18 C ANISOU 405 C5 5CM B 5 716 708 925 59 -81 -145 C HETATM 406 C5A 5CM B 5 -13.777 -8.458 13.655 1.00 6.94 C ANISOU 406 C5A 5CM B 5 852 855 929 -51 -129 -150 C HETATM 407 C6 5CM B 5 -15.633 -9.617 12.492 1.00 6.17 C ANISOU 407 C6 5CM B 5 674 745 927 58 -27 -90 C HETATM 408 O2 5CM B 5 -16.705 -9.564 9.106 1.00 7.06 O ANISOU 408 O2 5CM B 5 727 1026 930 -150 -119 -31 O HETATM 409 N4 5CM B 5 -13.270 -7.235 11.046 1.00 6.49 N ANISOU 409 N4 5CM B 5 734 745 989 -65 -22 -83 N HETATM 410 C1' 5CM B 5 -17.557 -10.749 11.352 1.00 6.36 C ANISOU 410 C1' 5CM B 5 648 766 1004 -75 90 -151 C HETATM 411 C2' 5CM B 5 -17.332 -12.227 11.416 1.00 6.87 C ANISOU 411 C2' 5CM B 5 716 825 1070 20 33 -211 C HETATM 412 C3' 5CM B 5 -18.558 -12.755 12.110 1.00 6.75 C ANISOU 412 C3' 5CM B 5 710 779 1075 -45 -10 -191 C HETATM 413 C4' 5CM B 5 -19.285 -11.483 12.495 1.00 6.91 C ANISOU 413 C4' 5CM B 5 802 758 1067 -58 29 -145 C HETATM 414 O4' 5CM B 5 -18.324 -10.469 12.507 1.00 6.40 O ANISOU 414 O4' 5CM B 5 711 709 1013 -71 101 -126 O HETATM 415 O3' 5CM B 5 -19.430 -13.491 11.283 1.00 6.72 O ANISOU 415 O3' 5CM B 5 720 748 1087 46 -47 -234 O HETATM 416 C5' 5CM B 5 -20.074 -11.515 13.773 1.00 7.00 C ANISOU 416 C5' 5CM B 5 752 832 1075 -33 30 -79 C HETATM 417 O5' 5CM B 5 -19.255 -11.797 14.866 1.00 6.82 O ANISOU 417 O5' 5CM B 5 769 774 1048 -64 120 -30 O HETATM 418 P 5CM B 5 -19.786 -11.530 16.334 1.00 6.98 P ANISOU 418 P 5CM B 5 876 736 1038 -105 206 -35 P HETATM 419 OP1 5CM B 5 -21.148 -12.133 16.510 1.00 7.80 O ANISOU 419 OP1 5CM B 5 934 856 1175 -194 304 -51 O HETATM 420 OP2 5CM B 5 -18.700 -11.950 17.247 1.00 7.79 O ANISOU 420 OP2 5CM B 5 1170 793 997 -166 237 -68 O ATOM 421 P DG B 6 -19.246 -15.073 11.019 1.00 6.64 P ANISOU 421 P DG B 6 678 751 1096 -110 53 -241 P ATOM 422 OP1 DG B 6 -20.548 -15.593 10.542 1.00 7.78 O ANISOU 422 OP1 DG B 6 766 959 1231 -171 7 -277 O ATOM 423 OP2 DG B 6 -18.618 -15.695 12.204 1.00 6.99 O ANISOU 423 OP2 DG B 6 875 722 1057 -49 153 -219 O ATOM 424 O5' DG B 6 -18.168 -15.159 9.851 1.00 6.71 O ANISOU 424 O5' DG B 6 704 863 984 6 16 -179 O ATOM 425 C5' DG B 6 -18.514 -14.864 8.506 1.00 6.85 C ANISOU 425 C5' DG B 6 746 919 936 0 -68 -126 C ATOM 426 C4' DG B 6 -17.264 -14.974 7.661 1.00 6.42 C ANISOU 426 C4' DG B 6 697 830 912 -72 -65 -105 C ATOM 427 O4' DG B 6 -16.380 -13.864 7.969 1.00 6.34 O ANISOU 427 O4' DG B 6 701 791 915 -16 -144 -93 O ATOM 428 C3' DG B 6 -16.427 -16.235 7.896 1.00 6.10 C ANISOU 428 C3' DG B 6 699 792 829 -51 -52 -125 C ATOM 429 O3' DG B 6 -15.827 -16.638 6.689 1.00 6.66 O ANISOU 429 O3' DG B 6 863 845 823 -156 63 -154 O ATOM 430 C2' DG B 6 -15.318 -15.751 8.825 1.00 6.30 C ANISOU 430 C2' DG B 6 774 760 859 -9 -92 -66 C ATOM 431 C1' DG B 6 -15.094 -14.380 8.211 1.00 5.98 C ANISOU 431 C1' DG B 6 641 747 883 -8 -122 -73 C ATOM 432 N9 DG B 6 -14.356 -13.421 9.016 1.00 5.97 N ANISOU 432 N9 DG B 6 631 795 841 28 -93 -69 N ATOM 433 C8 DG B 6 -14.156 -13.363 10.378 1.00 5.92 C ANISOU 433 C8 DG B 6 610 813 827 59 -67 -114 C ATOM 434 N7 DG B 6 -13.424 -12.346 10.743 1.00 6.00 N ANISOU 434 N7 DG B 6 615 798 865 49 -29 -102 N ATOM 435 C5 DG B 6 -13.137 -11.682 9.548 1.00 5.82 C ANISOU 435 C5 DG B 6 566 752 893 66 -56 -54 C ATOM 436 C6 DG B 6 -12.354 -10.536 9.276 1.00 6.31 C ANISOU 436 C6 DG B 6 605 810 984 53 -103 -38 C ATOM 437 O6 DG B 6 -11.741 -9.832 10.088 1.00 6.90 O ANISOU 437 O6 DG B 6 711 867 1044 -84 -117 -115 O ATOM 438 N1 DG B 6 -12.290 -10.237 7.918 1.00 6.60 N ANISOU 438 N1 DG B 6 636 887 983 82 -86 50 N ATOM 439 C2 DG B 6 -12.918 -10.948 6.931 1.00 6.80 C ANISOU 439 C2 DG B 6 687 953 946 113 -74 79 C ATOM 440 N2 DG B 6 -12.746 -10.508 5.674 1.00 7.81 N ANISOU 440 N2 DG B 6 865 1120 981 129 -50 154 N ATOM 441 N3 DG B 6 -13.645 -12.028 7.166 1.00 6.48 N ANISOU 441 N3 DG B 6 690 893 878 74 -106 32 N ATOM 442 C4 DG B 6 -13.699 -12.339 8.483 1.00 5.92 C ANISOU 442 C4 DG B 6 549 825 874 90 -97 -14 C ATOM 443 P DG B 7 -16.414 -17.874 5.851 1.00 6.63 P ANISOU 443 P DG B 7 821 898 801 -110 5 -151 P ATOM 444 OP1 DG B 7 -17.861 -17.635 5.603 1.00 7.64 O ANISOU 444 OP1 DG B 7 908 1104 893 -150 -12 -129 O ATOM 445 OP2 DG B 7 -15.993 -19.146 6.496 1.00 7.41 O ANISOU 445 OP2 DG B 7 1086 845 885 -120 30 -145 O ATOM 446 O5' DG B 7 -15.589 -17.737 4.504 1.00 7.18 O ANISOU 446 O5' DG B 7 895 1041 793 -62 31 -126 O ATOM 447 C5' DG B 7 -15.921 -16.703 3.576 1.00 7.47 C ANISOU 447 C5' DG B 7 871 1133 836 -48 -8 -91 C ATOM 448 C4' DG B 7 -14.682 -16.237 2.847 1.00 7.57 C ANISOU 448 C4' DG B 7 838 1178 862 -10 23 -132 C ATOM 449 O4' DG B 7 -13.914 -15.338 3.682 1.00 7.25 O ANISOU 449 O4' DG B 7 727 1118 908 7 -65 -91 O ATOM 450 C3' DG B 7 -13.732 -17.359 2.433 1.00 8.27 C ANISOU 450 C3' DG B 7 935 1348 860 17 72 -185 C ATOM 451 O3' DG B 7 -13.389 -17.102 1.074 1.00 9.44 O ANISOU 451 O3' DG B 7 1055 1631 902 92 68 -235 O ATOM 452 C2' DG B 7 -12.552 -17.209 3.393 1.00 8.04 C ANISOU 452 C2' DG B 7 866 1269 921 91 1 -132 C ATOM 453 C1' DG B 7 -12.530 -15.718 3.641 1.00 7.44 C ANISOU 453 C1' DG B 7 702 1204 923 43 -60 -69 C ATOM 454 N9 DG B 7 -12.014 -15.245 4.925 1.00 7.35 N ANISOU 454 N9 DG B 7 693 1158 941 55 -28 -61 N ATOM 455 C8 DG B 7 -12.392 -15.691 6.168 1.00 7.39 C ANISOU 455 C8 DG B 7 720 1137 954 58 -4 -51 C ATOM 456 N7 DG B 7 -11.851 -15.024 7.151 1.00 7.30 N ANISOU 456 N7 DG B 7 789 1020 964 133 -51 -72 N ATOM 457 C5 DG B 7 -11.075 -14.062 6.516 1.00 7.06 C ANISOU 457 C5 DG B 7 702 1005 975 148 -74 -45 C ATOM 458 C6 DG B 7 -10.264 -13.048 7.071 1.00 7.25 C ANISOU 458 C6 DG B 7 772 946 1038 185 -138 -47 C ATOM 459 O6 DG B 7 -10.089 -12.774 8.265 1.00 7.76 O ANISOU 459 O6 DG B 7 923 952 1074 154 -175 -39 O ATOM 460 N1 DG B 7 -9.631 -12.296 6.081 1.00 7.39 N ANISOU 460 N1 DG B 7 769 972 1067 85 -34 -47 N ATOM 461 C2 DG B 7 -9.788 -12.489 4.726 1.00 7.77 C ANISOU 461 C2 DG B 7 786 1091 1076 110 7 -23 C ATOM 462 N2 DG B 7 -9.109 -11.658 3.918 1.00 9.00 N ANISOU 462 N2 DG B 7 1033 1239 1149 -25 49 -11 N ATOM 463 N3 DG B 7 -10.565 -13.427 4.198 1.00 7.46 N ANISOU 463 N3 DG B 7 735 1109 989 116 -22 -57 N ATOM 464 C4 DG B 7 -11.169 -14.177 5.148 1.00 7.11 C ANISOU 464 C4 DG B 7 663 1076 960 144 -54 -69 C ATOM 465 P DC B 8 -12.613 -18.194 0.194 1.00 10.84 P ANISOU 465 P DC B 8 1262 1869 990 130 58 -423 P ATOM 466 OP1 DC B 8 -13.057 -18.027 -1.205 1.00 12.28 O ANISOU 466 OP1 DC B 8 1446 2186 1032 18 -28 -445 O ATOM 467 OP2 DC B 8 -12.753 -19.512 0.841 1.00 12.02 O ANISOU 467 OP2 DC B 8 1561 1879 1128 202 109 -495 O ATOM 468 O5' DC B 8 -11.088 -17.769 0.340 1.00 10.88 O ANISOU 468 O5' DC B 8 1190 1911 1033 219 70 -293 O ATOM 469 C5' DC B 8 -10.705 -16.539 -0.244 1.00 11.33 C ANISOU 469 C5' DC B 8 1227 2002 1075 261 66 -249 C ATOM 470 C4'A DC B 8 -9.296 -16.223 0.208 0.50 11.40 C ANISOU 470 C4'A DC B 8 1210 2028 1093 313 60 -237 C ATOM 471 C4'B DC B 8 -9.336 -16.103 0.219 0.50 11.34 C ANISOU 471 C4'B DC B 8 1213 2012 1082 319 58 -241 C ATOM 472 O4'A DC B 8 -9.311 -15.845 1.600 0.50 11.01 O ANISOU 472 O4'A DC B 8 1209 1908 1066 340 -27 -203 O ATOM 473 O4'B DC B 8 -9.347 -15.887 1.643 0.50 10.90 O ANISOU 473 O4'B DC B 8 1190 1898 1055 336 -17 -201 O ATOM 474 C3'A DC B 8 -8.297 -17.377 0.112 0.50 12.07 C ANISOU 474 C3'A DC B 8 1253 2173 1161 342 173 -238 C ATOM 475 C3'B DC B 8 -8.210 -17.098 -0.038 0.50 11.95 C ANISOU 475 C3'B DC B 8 1274 2130 1139 330 151 -247 C ATOM 476 O3'A DC B 8 -7.366 -17.038 -0.899 0.50 13.48 O ANISOU 476 O3'A DC B 8 1456 2431 1237 393 338 -298 O ATOM 477 O3'B DC B 8 -7.371 -16.505 -1.020 0.50 13.17 O ANISOU 477 O3'B DC B 8 1466 2337 1199 367 290 -305 O ATOM 478 C2'A DC B 8 -7.641 -17.453 1.490 0.50 11.67 C ANISOU 478 C2'A DC B 8 1251 2034 1149 330 81 -181 C ATOM 479 C2'B DC B 8 -7.518 -17.284 1.319 0.50 11.50 C ANISOU 479 C2'B DC B 8 1239 2002 1128 314 85 -172 C ATOM 480 C1'A DC B 8 -8.014 -16.113 2.098 0.50 10.85 C ANISOU 480 C1'A DC B 8 1184 1852 1085 243 -8 -134 C ATOM 481 C1'B DC B 8 -8.013 -16.068 2.086 0.50 10.76 C ANISOU 481 C1'B DC B 8 1177 1837 1075 246 -2 -130 C ATOM 482 N1 DC B 8 -8.122 -16.118 3.561 1.00 9.46 N ANISOU 482 N1 DC B 8 1006 1558 1030 193 -6 -54 N ATOM 483 C2 DC B 8 -7.431 -15.165 4.305 1.00 8.43 C ANISOU 483 C2 DC B 8 913 1308 983 145 65 -5 C ATOM 484 O2 DC B 8 -6.703 -14.349 3.716 1.00 9.54 O ANISOU 484 O2 DC B 8 1170 1470 984 -25 126 45 O ATOM 485 N3 DC B 8 -7.580 -15.186 5.650 1.00 7.47 N ANISOU 485 N3 DC B 8 812 1070 957 170 49 22 N ATOM 486 C4 DC B 8 -8.368 -16.091 6.242 1.00 7.33 C ANISOU 486 C4 DC B 8 759 1019 1006 212 50 -9 C ATOM 487 N4 DC B 8 -8.476 -16.042 7.577 1.00 7.27 N ANISOU 487 N4 DC B 8 779 966 1018 154 151 69 N ATOM 488 C5 DC B 8 -9.079 -17.071 5.485 1.00 8.07 C ANISOU 488 C5 DC B 8 836 1184 1045 213 28 -83 C ATOM 489 C6 DC B 8 -8.931 -17.035 4.159 1.00 8.85 C ANISOU 489 C6 DC B 8 920 1379 1064 204 19 -59 C ATOM 490 P A DA B 9 -6.167 -18.039 -1.275 0.38 14.76 P ANISOU 490 P A DA B 9 1707 2609 1293 447 465 -341 P ATOM 491 P B DA B 9 -6.158 -17.339 -1.662 0.62 14.44 P ANISOU 491 P B DA B 9 1714 2503 1268 386 403 -351 P ATOM 492 OP1A DA B 9 -5.901 -17.897 -2.720 0.38 15.46 O ANISOU 492 OP1A DA B 9 1874 2694 1307 466 503 -412 O ATOM 493 OP1B DA B 9 -5.843 -16.747 -2.977 0.62 15.45 O ANISOU 493 OP1B DA B 9 1894 2671 1304 374 448 -355 O ATOM 494 OP2A DA B 9 -6.496 -19.380 -0.748 0.38 15.50 O ANISOU 494 OP2A DA B 9 1845 2734 1311 484 454 -364 O ATOM 495 OP2B DA B 9 -6.477 -18.783 -1.552 0.62 14.98 O ANISOU 495 OP2B DA B 9 1797 2614 1282 422 500 -439 O ATOM 496 O5'A DA B 9 -4.930 -17.461 -0.458 0.38 14.06 O ANISOU 496 O5'A DA B 9 1616 2440 1288 441 444 -235 O ATOM 497 O5'B DA B 9 -4.946 -17.049 -0.676 0.62 13.72 O ANISOU 497 O5'B DA B 9 1582 2366 1265 518 366 -237 O ATOM 498 C5'A DA B 9 -4.486 -16.129 -0.676 0.38 13.06 C ANISOU 498 C5'A DA B 9 1508 2209 1246 476 398 -142 C ATOM 499 C5'B DA B 9 -4.421 -15.734 -0.609 0.62 12.64 C ANISOU 499 C5'B DA B 9 1455 2135 1214 567 393 -143 C ATOM 500 C4'A DA B 9 -3.372 -15.832 0.304 0.38 11.95 C ANISOU 500 C4'A DA B 9 1419 1935 1187 476 373 -59 C ATOM 501 C4'B DA B 9 -3.288 -15.670 0.392 0.62 11.83 C ANISOU 501 C4'B DA B 9 1415 1915 1165 529 400 -63 C ATOM 502 O4'A DA B 9 -3.918 -15.889 1.641 0.38 11.76 O ANISOU 502 O4'A DA B 9 1473 1843 1151 500 320 -48 O ATOM 503 O4'B DA B 9 -3.844 -15.751 1.719 0.62 12.04 O ANISOU 503 O4'B DA B 9 1570 1866 1139 592 347 -41 O ATOM 504 C3'A DA B 9 -2.211 -16.826 0.265 0.38 11.09 C ANISOU 504 C3'A DA B 9 1310 1732 1173 436 380 -3 C ATOM 505 C3'B DA B 9 -2.223 -16.768 0.271 0.62 10.98 C ANISOU 505 C3'B DA B 9 1285 1716 1169 450 390 5 C ATOM 506 O3'A DA B 9 -1.012 -16.086 0.041 0.38 10.44 O ANISOU 506 O3'A DA B 9 1234 1567 1163 381 447 40 O ATOM 507 O3'B DA B 9 -1.006 -16.067 0.036 0.62 10.38 O ANISOU 507 O3'B DA B 9 1219 1560 1166 383 448 43 O ATOM 508 C2'A DA B 9 -2.251 -17.526 1.628 0.38 11.03 C ANISOU 508 C2'A DA B 9 1315 1715 1161 470 350 -8 C ATOM 509 C2'B DA B 9 -2.281 -17.507 1.610 0.62 11.00 C ANISOU 509 C2'B DA B 9 1311 1704 1164 492 366 7 C ATOM 510 C1'A DA B 9 -3.007 -16.535 2.505 0.38 10.99 C ANISOU 510 C1'A DA B 9 1327 1713 1136 474 296 -34 C ATOM 511 C1'B DA B 9 -2.986 -16.518 2.533 0.62 11.03 C ANISOU 511 C1'B DA B 9 1349 1710 1132 514 307 -21 C ATOM 512 N9 DA B 9 -3.823 -17.129 3.555 1.00 10.28 N ANISOU 512 N9 DA B 9 1177 1626 1102 408 231 -77 N ATOM 513 C8 DA B 9 -4.703 -18.168 3.403 1.00 9.84 C ANISOU 513 C8 DA B 9 989 1663 1088 351 225 -172 C ATOM 514 N7 DA B 9 -5.331 -18.481 4.510 1.00 9.32 N ANISOU 514 N7 DA B 9 843 1638 1060 348 176 -217 N ATOM 515 C5 DA B 9 -4.833 -17.581 5.443 1.00 8.93 C ANISOU 515 C5 DA B 9 805 1500 1087 449 136 -194 C ATOM 516 C6 DA B 9 -5.091 -17.394 6.815 1.00 8.95 C ANISOU 516 C6 DA B 9 830 1469 1100 435 127 -222 C ATOM 517 N6 DA B 9 -5.959 -18.145 7.489 1.00 8.86 N ANISOU 517 N6 DA B 9 796 1494 1075 353 166 -218 N ATOM 518 N1 DA B 9 -4.427 -16.412 7.457 1.00 9.34 N ANISOU 518 N1 DA B 9 962 1459 1127 469 137 -246 N ATOM 519 C2 DA B 9 -3.556 -15.666 6.773 1.00 9.93 C ANISOU 519 C2 DA B 9 1139 1457 1177 447 103 -211 C ATOM 520 N3 DA B 9 -3.224 -15.746 5.487 1.00 9.91 N ANISOU 520 N3 DA B 9 1180 1415 1169 484 134 -138 N ATOM 521 C4 DA B 9 -3.906 -16.733 4.874 1.00 9.51 C ANISOU 521 C4 DA B 9 1037 1468 1106 443 163 -148 C ATOM 522 P DA B 10 0.420 -16.821 0.017 1.00 10.02 P ANISOU 522 P DA B 10 1249 1418 1141 314 516 82 P ATOM 523 OP1 DA B 10 1.343 -15.986 -0.784 1.00 10.40 O ANISOU 523 OP1 DA B 10 1329 1437 1184 197 492 110 O ATOM 524 OP2 DA B 10 0.221 -18.249 -0.371 1.00 10.32 O ANISOU 524 OP2 DA B 10 1344 1394 1182 272 575 41 O ATOM 525 O5' DA B 10 0.879 -16.805 1.541 1.00 9.97 O ANISOU 525 O5' DA B 10 1279 1350 1160 298 431 104 O ATOM 526 C5' DA B 10 1.039 -15.549 2.195 1.00 10.86 C ANISOU 526 C5' DA B 10 1422 1495 1210 179 418 82 C ATOM 527 C4' DA B 10 1.370 -15.786 3.647 1.00 11.33 C ANISOU 527 C4' DA B 10 1413 1615 1278 228 387 101 C ATOM 528 O4' DA B 10 0.206 -16.374 4.267 1.00 11.23 O ANISOU 528 O4' DA B 10 1410 1599 1259 303 443 157 O ATOM 529 C3' DA B 10 2.548 -16.732 3.890 1.00 12.17 C ANISOU 529 C3' DA B 10 1485 1754 1384 198 271 45 C ATOM 530 O3' DA B 10 3.526 -15.974 4.607 1.00 12.87 O ANISOU 530 O3' DA B 10 1445 1951 1492 9 289 44 O ATOM 531 C2' DA B 10 1.930 -17.884 4.683 1.00 11.99 C ANISOU 531 C2' DA B 10 1472 1691 1391 233 217 79 C ATOM 532 C1' DA B 10 0.668 -17.249 5.264 1.00 11.31 C ANISOU 532 C1' DA B 10 1416 1589 1291 288 298 149 C ATOM 533 N9 DA B 10 -0.403 -18.190 5.567 1.00 10.97 N ANISOU 533 N9 DA B 10 1365 1569 1234 400 269 139 N ATOM 534 C8 DA B 10 -0.955 -19.104 4.718 1.00 10.86 C ANISOU 534 C8 DA B 10 1367 1544 1216 451 258 149 C ATOM 535 N7 DA B 10 -1.915 -19.820 5.257 1.00 10.59 N ANISOU 535 N7 DA B 10 1272 1564 1187 498 260 118 N ATOM 536 C5 DA B 10 -1.999 -19.328 6.550 1.00 10.36 C ANISOU 536 C5 DA B 10 1233 1528 1173 557 261 154 C ATOM 537 C6 DA B 10 -2.815 -19.676 7.638 1.00 10.44 C ANISOU 537 C6 DA B 10 1242 1541 1183 499 299 136 C ATOM 538 N6 DA B 10 -3.735 -20.640 7.572 1.00 10.58 N ANISOU 538 N6 DA B 10 1278 1515 1225 449 299 100 N ATOM 539 N1 DA B 10 -2.638 -19.000 8.789 1.00 10.53 N ANISOU 539 N1 DA B 10 1250 1598 1152 560 262 131 N ATOM 540 C2 DA B 10 -1.716 -18.035 8.846 1.00 10.90 C ANISOU 540 C2 DA B 10 1358 1617 1168 553 228 129 C ATOM 541 N3 DA B 10 -0.883 -17.625 7.892 1.00 10.96 N ANISOU 541 N3 DA B 10 1399 1595 1169 531 216 129 N ATOM 542 C4 DA B 10 -1.078 -18.322 6.759 1.00 10.52 C ANISOU 542 C4 DA B 10 1284 1528 1186 545 253 148 C ATOM 543 P DT B 11 4.956 -16.609 4.992 1.00 13.46 P ANISOU 543 P DT B 11 1428 2127 1557 -139 248 82 P ATOM 544 OP1 DT B 11 5.909 -15.491 5.161 1.00 14.57 O ANISOU 544 OP1 DT B 11 1644 2250 1642 -281 189 89 O ATOM 545 OP2 DT B 11 5.260 -17.698 4.049 1.00 13.84 O ANISOU 545 OP2 DT B 11 1520 2181 1557 -204 248 35 O ATOM 546 O5' DT B 11 4.698 -17.286 6.405 1.00 13.14 O ANISOU 546 O5' DT B 11 1400 2042 1551 -129 211 131 O ATOM 547 C5' DT B 11 4.347 -16.471 7.510 1.00 13.49 C ANISOU 547 C5' DT B 11 1522 2008 1597 -161 193 166 C ATOM 548 C4' DT B 11 3.980 -17.388 8.651 1.00 13.48 C ANISOU 548 C4' DT B 11 1467 1982 1673 -120 89 260 C ATOM 549 O4' DT B 11 2.787 -18.104 8.268 1.00 12.79 O ANISOU 549 O4' DT B 11 1328 1849 1685 -72 85 306 O ATOM 550 C3' DT B 11 5.028 -18.454 8.977 1.00 14.36 C ANISOU 550 C3' DT B 11 1608 2113 1735 -59 3 274 C ATOM 551 O3' DT B 11 5.436 -18.330 10.339 1.00 15.93 O ANISOU 551 O3' DT B 11 1933 2315 1804 -70 -83 254 O ATOM 552 C2' DT B 11 4.298 -19.775 8.714 1.00 13.58 C ANISOU 552 C2' DT B 11 1442 1999 1717 16 -4 280 C ATOM 553 C1' DT B 11 2.856 -19.332 8.935 1.00 12.56 C ANISOU 553 C1' DT B 11 1281 1828 1662 17 60 311 C ATOM 554 N1 DT B 11 1.804 -20.241 8.397 1.00 11.45 N ANISOU 554 N1 DT B 11 1138 1625 1587 178 118 318 N ATOM 555 C2 DT B 11 0.768 -20.569 9.238 1.00 10.98 C ANISOU 555 C2 DT B 11 1099 1522 1551 271 97 303 C ATOM 556 O2 DT B 11 0.666 -20.144 10.374 1.00 11.57 O ANISOU 556 O2 DT B 11 1284 1548 1562 257 99 267 O ATOM 557 N3 DT B 11 -0.158 -21.425 8.707 1.00 10.52 N ANISOU 557 N3 DT B 11 993 1474 1531 377 107 330 N ATOM 558 C4 DT B 11 -0.155 -21.966 7.441 1.00 10.87 C ANISOU 558 C4 DT B 11 1071 1527 1531 374 161 297 C ATOM 559 O4 DT B 11 -1.057 -22.721 7.088 1.00 11.18 O ANISOU 559 O4 DT B 11 1171 1548 1529 347 203 226 O ATOM 560 C5 DT B 11 0.949 -21.569 6.599 1.00 11.39 C ANISOU 560 C5 DT B 11 1159 1632 1535 328 209 285 C ATOM 561 C7 DT B 11 1.027 -22.112 5.204 1.00 11.90 C ANISOU 561 C7 DT B 11 1280 1712 1531 319 270 211 C ATOM 562 C6 DT B 11 1.872 -20.738 7.111 1.00 11.24 C ANISOU 562 C6 DT B 11 1082 1636 1552 300 168 318 C TER 563 DT B 11 ATOM 564 N SER C 136 -17.721 -24.521 -2.272 1.00 23.08 N ANISOU 564 N SER C 136 3682 2958 2129 -88 117 -606 N ATOM 565 CA SER C 136 -18.921 -24.118 -1.551 1.00 22.87 C ANISOU 565 CA SER C 136 3637 2925 2127 -108 125 -606 C ATOM 566 C SER C 136 -19.063 -24.873 -0.233 1.00 22.34 C ANISOU 566 C SER C 136 3557 2834 2098 -144 128 -646 C ATOM 567 O SER C 136 -19.993 -24.630 0.538 1.00 23.12 O ANISOU 567 O SER C 136 3670 2955 2160 -138 126 -592 O ATOM 568 N GLU C 137 -18.135 -25.790 0.022 1.00 20.97 N ANISOU 568 N GLU C 137 3327 2622 2019 -216 120 -700 N ATOM 569 CA GLU C 137 -18.188 -26.609 1.224 1.00 19.38 C ANISOU 569 CA GLU C 137 3086 2349 1928 -272 148 -782 C ATOM 570 C GLU C 137 -17.866 -25.783 2.463 1.00 17.36 C ANISOU 570 C GLU C 137 2714 2054 1829 -405 188 -828 C ATOM 571 O GLU C 137 -16.952 -24.958 2.454 1.00 17.39 O ANISOU 571 O GLU C 137 2724 2051 1834 -320 263 -787 O ATOM 572 CB GLU C 137 -17.223 -27.794 1.112 1.00 19.57 C ANISOU 572 CB GLU C 137 3156 2343 1938 -251 140 -807 C ATOM 573 N ARG C 138 -18.633 -26.018 3.524 1.00 15.87 N ANISOU 573 N ARG C 138 2419 1849 1760 -539 185 -829 N ATOM 574 CA ARG C 138 -18.393 -25.388 4.818 1.00 14.64 C ANISOU 574 CA ARG C 138 2171 1657 1733 -542 210 -728 C ATOM 575 C ARG C 138 -18.304 -26.478 5.883 1.00 14.65 C ANISOU 575 C ARG C 138 2184 1537 1844 -492 359 -628 C ATOM 576 O ARG C 138 -19.235 -26.679 6.665 1.00 15.16 O ANISOU 576 O ARG C 138 2240 1607 1915 -595 419 -533 O ATOM 577 CB ARG C 138 -19.510 -24.396 5.155 1.00 13.87 C ANISOU 577 CB ARG C 138 1979 1654 1637 -525 120 -620 C ATOM 578 CG ARG C 138 -19.724 -23.318 4.101 1.00 13.52 C ANISOU 578 CG ARG C 138 1924 1647 1565 -480 39 -520 C ATOM 579 CD ARG C 138 -20.859 -22.370 4.471 1.00 12.80 C ANISOU 579 CD ARG C 138 1770 1604 1490 -490 -11 -417 C ATOM 580 NE ARG C 138 -20.514 -21.531 5.617 1.00 11.71 N ANISOU 580 NE ARG C 138 1527 1513 1410 -457 -23 -307 N ATOM 581 CZ ARG C 138 -19.874 -20.368 5.530 1.00 11.16 C ANISOU 581 CZ ARG C 138 1403 1488 1349 -393 8 -148 C ATOM 582 NH1 ARG C 138 -19.516 -19.885 4.348 1.00 11.76 N ANISOU 582 NH1 ARG C 138 1538 1609 1322 -285 -4 -73 N ATOM 583 NH2 ARG C 138 -19.599 -19.679 6.624 1.00 10.42 N ANISOU 583 NH2 ARG C 138 1201 1420 1337 -435 -68 -104 N ATOM 584 N PRO C 139 -17.169 -27.188 5.918 1.00 14.65 N ANISOU 584 N PRO C 139 2215 1447 1904 -354 398 -532 N ATOM 585 CA PRO C 139 -17.116 -28.416 6.720 1.00 14.54 C ANISOU 585 CA PRO C 139 2263 1326 1937 -198 418 -478 C ATOM 586 C PRO C 139 -16.707 -28.192 8.176 1.00 13.92 C ANISOU 586 C PRO C 139 2152 1201 1934 -179 411 -412 C ATOM 587 O PRO C 139 -16.756 -29.133 8.971 1.00 15.15 O ANISOU 587 O PRO C 139 2458 1263 2034 -137 325 -348 O ATOM 588 CB PRO C 139 -16.063 -29.251 5.995 1.00 15.24 C ANISOU 588 CB PRO C 139 2371 1448 1973 -158 420 -479 C ATOM 589 CG PRO C 139 -15.137 -28.237 5.410 1.00 15.43 C ANISOU 589 CG PRO C 139 2361 1538 1965 -189 448 -480 C ATOM 590 CD PRO C 139 -15.971 -27.018 5.079 1.00 15.08 C ANISOU 590 CD PRO C 139 2300 1498 1930 -298 411 -512 C ATOM 591 N PHE C 140 -16.312 -26.972 8.524 1.00 11.92 N ANISOU 591 N PHE C 140 1676 1024 1830 -203 474 -406 N ATOM 592 CA PHE C 140 -15.919 -26.661 9.893 1.00 10.95 C ANISOU 592 CA PHE C 140 1479 921 1760 -125 575 -248 C ATOM 593 C PHE C 140 -17.141 -26.117 10.610 1.00 10.21 C ANISOU 593 C PHE C 140 1437 803 1638 -74 560 -165 C ATOM 594 O PHE C 140 -17.873 -25.309 10.046 1.00 11.34 O ANISOU 594 O PHE C 140 1598 1066 1643 115 636 36 O ATOM 595 CB PHE C 140 -14.785 -25.635 9.882 1.00 11.58 C ANISOU 595 CB PHE C 140 1492 1040 1867 -26 574 -193 C ATOM 596 CG PHE C 140 -13.545 -26.132 9.205 1.00 12.54 C ANISOU 596 CG PHE C 140 1593 1180 1992 76 552 -105 C ATOM 597 CD1 PHE C 140 -12.546 -26.752 9.932 1.00 14.57 C ANISOU 597 CD1 PHE C 140 1926 1500 2109 129 410 -18 C ATOM 598 CD2 PHE C 140 -13.376 -25.970 7.836 1.00 12.60 C ANISOU 598 CD2 PHE C 140 1619 1157 2011 111 673 -171 C ATOM 599 CE1 PHE C 140 -11.402 -27.226 9.301 1.00 15.39 C ANISOU 599 CE1 PHE C 140 2070 1614 2163 159 411 -15 C ATOM 600 CE2 PHE C 140 -12.246 -26.452 7.197 1.00 13.99 C ANISOU 600 CE2 PHE C 140 1852 1373 2090 201 633 -120 C ATOM 601 CZ PHE C 140 -11.253 -27.069 7.937 1.00 15.09 C ANISOU 601 CZ PHE C 140 2011 1565 2155 181 519 -43 C ATOM 602 N PHE C 141 -17.390 -26.565 11.837 1.00 9.25 N ANISOU 602 N PHE C 141 1259 720 1537 -237 443 -191 N ATOM 603 CA PHE C 141 -18.580 -26.095 12.536 1.00 9.04 C ANISOU 603 CA PHE C 141 1181 809 1444 -227 298 -161 C ATOM 604 C PHE C 141 -18.421 -26.027 14.042 1.00 8.14 C ANISOU 604 C PHE C 141 969 751 1374 -213 196 -205 C ATOM 605 O PHE C 141 -17.615 -26.736 14.657 1.00 8.41 O ANISOU 605 O PHE C 141 1049 741 1404 -93 184 -202 O ATOM 606 CB PHE C 141 -19.823 -26.915 12.159 1.00 9.94 C ANISOU 606 CB PHE C 141 1369 940 1466 -236 213 -195 C ATOM 607 CG PHE C 141 -19.818 -28.316 12.705 1.00 10.33 C ANISOU 607 CG PHE C 141 1516 916 1494 -299 120 -227 C ATOM 608 CD1 PHE C 141 -19.163 -29.330 12.032 1.00 11.24 C ANISOU 608 CD1 PHE C 141 1738 937 1596 -347 142 -240 C ATOM 609 CD2 PHE C 141 -20.456 -28.610 13.901 1.00 10.56 C ANISOU 609 CD2 PHE C 141 1486 1022 1504 -453 56 -146 C ATOM 610 CE1 PHE C 141 -19.154 -30.608 12.536 1.00 12.20 C ANISOU 610 CE1 PHE C 141 1916 1041 1676 -289 94 -153 C ATOM 611 CE2 PHE C 141 -20.451 -29.898 14.403 1.00 11.56 C ANISOU 611 CE2 PHE C 141 1691 1130 1570 -503 34 -36 C ATOM 612 CZ PHE C 141 -19.799 -30.890 13.719 1.00 12.26 C ANISOU 612 CZ PHE C 141 1868 1123 1666 -401 30 -36 C ATOM 613 N CYS C 142 -19.229 -25.147 14.614 1.00 7.64 N ANISOU 613 N CYS C 142 847 745 1311 -258 166 -200 N ATOM 614 CA CYS C 142 -19.268 -24.896 16.041 1.00 7.51 C ANISOU 614 CA CYS C 142 786 794 1273 -196 48 -239 C ATOM 615 C CYS C 142 -20.059 -25.964 16.787 1.00 7.12 C ANISOU 615 C CYS C 142 672 910 1123 -208 -25 -90 C ATOM 616 O CYS C 142 -21.180 -26.279 16.396 1.00 7.12 O ANISOU 616 O CYS C 142 738 950 1018 -314 -69 -40 O ATOM 617 CB CYS C 142 -19.931 -23.549 16.256 1.00 8.54 C ANISOU 617 CB CYS C 142 870 936 1440 -87 -13 -419 C ATOM 618 SG CYS C 142 -20.096 -23.109 17.988 1.00 9.69 S ANISOU 618 SG CYS C 142 830 1248 1604 86 -238 -695 S ATOM 619 N ASN C 143 -19.496 -26.478 17.882 1.00 7.99 N ANISOU 619 N ASN C 143 691 1199 1146 -203 -180 -27 N ATOM 620 CA ASN C 143 -20.158 -27.529 18.651 1.00 9.54 C ANISOU 620 CA ASN C 143 833 1619 1173 -194 -180 101 C ATOM 621 C ASN C 143 -21.199 -27.017 19.642 1.00 11.00 C ANISOU 621 C ASN C 143 915 2071 1194 38 -151 174 C ATOM 622 O ASN C 143 -21.858 -27.827 20.301 1.00 12.96 O ANISOU 622 O ASN C 143 1080 2536 1308 3 -50 262 O ATOM 623 CB ASN C 143 -19.139 -28.414 19.377 1.00 9.84 C ANISOU 623 CB ASN C 143 974 1538 1226 -152 -266 95 C ATOM 624 CG ASN C 143 -18.204 -29.135 18.428 1.00 9.86 C ANISOU 624 CG ASN C 143 1133 1342 1273 -183 -292 0 C ATOM 625 OD1 ASN C 143 -18.605 -29.603 17.362 1.00 10.61 O ANISOU 625 OD1 ASN C 143 1336 1415 1281 -277 -240 -135 O ATOM 626 ND2 ASN C 143 -16.940 -29.233 18.816 1.00 10.48 N ANISOU 626 ND2 ASN C 143 1331 1317 1335 3 -295 35 N ATOM 627 N APHE C 144 -21.486 -25.747 19.670 0.53 10.02 N ANISOU 627 N APHE C 144 820 1826 1162 71 -109 63 N ATOM 628 N BPHE C 144 -21.192 -25.660 19.813 0.47 10.62 N ANISOU 628 N BPHE C 144 838 2053 1145 243 -164 152 N ATOM 629 CA APHE C 144 -22.555 -25.359 20.549 0.53 8.34 C ANISOU 629 CA APHE C 144 657 1362 1148 -129 -101 -22 C ATOM 630 CA BPHE C 144 -22.144 -24.797 20.598 0.47 9.91 C ANISOU 630 CA BPHE C 144 872 1761 1134 126 -94 94 C ATOM 631 C APHE C 144 -23.697 -24.716 19.790 0.53 8.12 C ANISOU 631 C APHE C 144 674 1360 1051 108 -33 19 C ATOM 632 C BPHE C 144 -23.496 -24.699 19.834 0.47 9.00 C ANISOU 632 C BPHE C 144 851 1501 1067 124 -78 37 C ATOM 633 O APHE C 144 -24.817 -24.665 20.297 0.53 8.36 O ANISOU 633 O APHE C 144 690 1477 1009 490 4 139 O ATOM 634 O BPHE C 144 -24.553 -25.059 20.353 0.47 9.24 O ANISOU 634 O BPHE C 144 943 1500 1066 271 -111 56 O ATOM 635 CB APHE C 144 -22.029 -24.376 21.577 0.53 8.10 C ANISOU 635 CB APHE C 144 796 1061 1219 -126 -219 -97 C ATOM 636 CB BPHE C 144 -21.692 -23.290 20.790 0.47 9.29 C ANISOU 636 CB BPHE C 144 844 1540 1147 87 -87 121 C ATOM 637 CG APHE C 144 -21.006 -24.955 22.516 0.53 8.73 C ANISOU 637 CG APHE C 144 1029 986 1303 -20 -416 -196 C ATOM 638 CG BPHE C 144 -20.553 -23.004 21.806 0.47 9.01 C ANISOU 638 CG BPHE C 144 911 1355 1156 60 -113 115 C ATOM 639 CD1APHE C 144 -21.391 -25.468 23.748 0.53 9.70 C ANISOU 639 CD1APHE C 144 1391 934 1362 -46 -476 -226 C ATOM 640 CD1BPHE C 144 -20.809 -22.486 23.087 0.47 9.36 C ANISOU 640 CD1BPHE C 144 1158 1207 1191 136 -81 101 C ATOM 641 CD2APHE C 144 -19.661 -24.978 22.175 0.53 9.85 C ANISOU 641 CD2APHE C 144 1220 1139 1385 85 -429 -264 C ATOM 642 CD2BPHE C 144 -19.236 -23.101 21.412 0.47 8.94 C ANISOU 642 CD2BPHE C 144 928 1304 1165 32 -152 119 C ATOM 643 CE1APHE C 144 -20.458 -25.993 24.613 0.53 10.72 C ANISOU 643 CE1APHE C 144 1636 1028 1409 69 -492 -204 C ATOM 644 CE1BPHE C 144 -19.757 -22.170 23.964 0.47 9.57 C ANISOU 644 CE1BPHE C 144 1295 1131 1209 96 -84 94 C ATOM 645 CE2APHE C 144 -18.727 -25.502 23.047 0.53 10.58 C ANISOU 645 CE2APHE C 144 1408 1183 1431 169 -464 -291 C ATOM 646 CE2BPHE C 144 -18.202 -22.805 22.286 0.47 9.45 C ANISOU 646 CE2BPHE C 144 1124 1289 1179 24 -198 128 C ATOM 647 CZ APHE C 144 -19.131 -26.003 24.263 0.53 10.76 C ANISOU 647 CZ APHE C 144 1561 1098 1429 166 -535 -238 C ATOM 648 CZ BPHE C 144 -18.463 -22.326 23.554 0.47 9.63 C ANISOU 648 CZ BPHE C 144 1289 1178 1191 32 -179 127 C ATOM 649 N CYS C 145 -23.425 -24.195 18.593 1.00 7.48 N ANISOU 649 N CYS C 145 683 1143 1017 -76 -92 -28 N ATOM 650 CA CYS C 145 -24.548 -23.637 17.824 1.00 6.91 C ANISOU 650 CA CYS C 145 644 982 999 -188 -45 -47 C ATOM 651 C CYS C 145 -24.596 -24.080 16.367 1.00 6.44 C ANISOU 651 C CYS C 145 658 825 965 -305 -38 -20 C ATOM 652 O CYS C 145 -25.504 -23.690 15.643 1.00 6.75 O ANISOU 652 O CYS C 145 702 962 901 -280 -126 20 O ATOM 653 CB CYS C 145 -24.570 -22.097 17.882 1.00 7.31 C ANISOU 653 CB CYS C 145 716 1022 1040 -233 73 -128 C ATOM 654 SG CYS C 145 -23.372 -21.307 16.753 1.00 7.30 S ANISOU 654 SG CYS C 145 706 970 1096 -294 90 -224 S ATOM 655 N GLY C 146 -23.612 -24.868 15.935 1.00 6.81 N ANISOU 655 N GLY C 146 741 855 990 -298 28 -80 N ATOM 656 CA GLY C 146 -23.647 -25.440 14.604 1.00 7.37 C ANISOU 656 CA GLY C 146 849 932 1021 -293 4 -117 C ATOM 657 C GLY C 146 -23.271 -24.507 13.461 1.00 7.26 C ANISOU 657 C GLY C 146 798 928 1032 -266 62 -110 C ATOM 658 O GLY C 146 -23.309 -24.926 12.310 1.00 7.90 O ANISOU 658 O GLY C 146 1038 971 994 -340 71 -111 O ATOM 659 N LYS C 147 -22.900 -23.261 13.739 1.00 7.18 N ANISOU 659 N LYS C 147 798 841 1091 -294 125 -94 N ATOM 660 CA ALYS C 147 -22.512 -22.374 12.651 0.63 7.59 C ANISOU 660 CA ALYS C 147 903 834 1148 -197 183 -88 C ATOM 661 CA BLYS C 147 -22.496 -22.350 12.677 0.37 7.70 C ANISOU 661 CA BLYS C 147 934 861 1132 -224 153 -78 C ATOM 662 C LYS C 147 -21.326 -22.950 11.898 1.00 7.38 C ANISOU 662 C LYS C 147 870 817 1116 -224 144 -100 C ATOM 663 O LYS C 147 -20.376 -23.466 12.490 1.00 7.47 O ANISOU 663 O LYS C 147 876 857 1106 -133 183 -160 O ATOM 664 CB ALYS C 147 -22.227 -20.953 13.144 0.63 8.52 C ANISOU 664 CB ALYS C 147 1050 925 1262 -169 210 -59 C ATOM 665 CB BLYS C 147 -22.110 -20.993 13.263 0.37 8.73 C ANISOU 665 CB BLYS C 147 1145 967 1205 -207 162 -45 C ATOM 666 CG ALYS C 147 -23.447 -20.039 13.039 0.63 9.38 C ANISOU 666 CG ALYS C 147 1163 1059 1343 -145 189 -58 C ATOM 667 CG BLYS C 147 -22.137 -19.845 12.266 0.37 9.79 C ANISOU 667 CG BLYS C 147 1359 1106 1255 -212 126 -41 C ATOM 668 CD ALYS C 147 -23.251 -18.661 13.666 0.63 10.07 C ANISOU 668 CD ALYS C 147 1254 1154 1417 -117 126 -66 C ATOM 669 CD BLYS C 147 -23.521 -19.192 12.137 0.37 10.75 C ANISOU 669 CD BLYS C 147 1489 1295 1302 -196 84 -61 C ATOM 670 CE ALYS C 147 -22.133 -17.878 13.014 0.63 10.66 C ANISOU 670 CE ALYS C 147 1338 1241 1472 -72 106 -54 C ATOM 671 CE BLYS C 147 -23.511 -17.995 11.164 0.37 11.27 C ANISOU 671 CE BLYS C 147 1543 1414 1327 -238 80 -84 C ATOM 672 NZ ALYS C 147 -22.410 -17.589 11.589 0.63 10.29 N ANISOU 672 NZ ALYS C 147 1273 1151 1487 -49 46 -78 N ATOM 673 NZ BLYS C 147 -24.862 -17.393 10.931 0.37 11.46 N ANISOU 673 NZ BLYS C 147 1563 1454 1339 -275 66 -90 N ATOM 674 N THR C 148 -21.401 -22.860 10.577 1.00 7.99 N ANISOU 674 N THR C 148 981 956 1100 -255 140 -124 N ATOM 675 CA THR C 148 -20.416 -23.485 9.706 1.00 8.44 C ANISOU 675 CA THR C 148 1105 976 1124 -349 146 -237 C ATOM 676 C THR C 148 -19.490 -22.458 9.058 1.00 7.66 C ANISOU 676 C THR C 148 974 881 1054 -303 102 -236 C ATOM 677 O THR C 148 -19.842 -21.276 8.908 1.00 7.97 O ANISOU 677 O THR C 148 1008 952 1069 -255 100 -150 O ATOM 678 CB THR C 148 -21.101 -24.293 8.591 1.00 9.81 C ANISOU 678 CB THR C 148 1316 1169 1242 -481 49 -248 C ATOM 679 OG1 THR C 148 -21.749 -23.381 7.692 1.00 10.63 O ANISOU 679 OG1 THR C 148 1442 1345 1251 -502 -37 -244 O ATOM 680 CG2 THR C 148 -22.117 -25.277 9.180 1.00 10.46 C ANISOU 680 CG2 THR C 148 1415 1235 1325 -614 25 -242 C ATOM 681 N TYR C 149 -18.314 -22.941 8.661 1.00 7.54 N ANISOU 681 N TYR C 149 1014 810 1042 -203 136 -281 N ATOM 682 CA TYR C 149 -17.220 -22.123 8.142 1.00 7.48 C ANISOU 682 CA TYR C 149 1013 823 1005 -180 126 -273 C ATOM 683 C TYR C 149 -16.510 -22.808 6.984 1.00 8.01 C ANISOU 683 C TYR C 149 1126 853 1064 -210 171 -310 C ATOM 684 O TYR C 149 -16.411 -24.037 6.930 1.00 8.71 O ANISOU 684 O TYR C 149 1266 896 1148 -113 224 -315 O ATOM 685 CB TYR C 149 -16.212 -21.801 9.270 1.00 7.23 C ANISOU 685 CB TYR C 149 938 830 978 -122 66 -267 C ATOM 686 CG TYR C 149 -16.867 -20.872 10.246 1.00 6.45 C ANISOU 686 CG TYR C 149 753 748 950 -115 44 -202 C ATOM 687 CD1 TYR C 149 -16.937 -19.511 9.971 1.00 6.62 C ANISOU 687 CD1 TYR C 149 767 785 964 -75 23 -204 C ATOM 688 CD2 TYR C 149 -17.541 -21.350 11.363 1.00 6.73 C ANISOU 688 CD2 TYR C 149 896 705 957 -138 72 -180 C ATOM 689 CE1 TYR C 149 -17.628 -18.653 10.805 1.00 6.55 C ANISOU 689 CE1 TYR C 149 739 760 988 -120 32 -201 C ATOM 690 CE2 TYR C 149 -18.226 -20.499 12.207 1.00 6.80 C ANISOU 690 CE2 TYR C 149 858 778 947 -127 44 -164 C ATOM 691 CZ TYR C 149 -18.283 -19.157 11.914 1.00 6.56 C ANISOU 691 CZ TYR C 149 757 793 942 -131 72 -210 C ATOM 692 OH TYR C 149 -18.998 -18.337 12.750 1.00 7.19 O ANISOU 692 OH TYR C 149 922 844 965 -83 180 -175 O ATOM 693 N ARG C 150 -15.997 -21.986 6.075 1.00 8.36 N ANISOU 693 N ARG C 150 1181 933 1064 -194 245 -401 N ATOM 694 CA ARG C 150 -15.209 -22.451 4.941 1.00 9.28 C ANISOU 694 CA ARG C 150 1294 1107 1126 -108 310 -380 C ATOM 695 C ARG C 150 -13.870 -23.033 5.357 1.00 9.39 C ANISOU 695 C ARG C 150 1232 1111 1226 -46 285 -401 C ATOM 696 O ARG C 150 -13.344 -23.909 4.684 1.00 10.74 O ANISOU 696 O ARG C 150 1524 1242 1314 104 256 -512 O ATOM 697 CB ARG C 150 -14.955 -21.292 3.981 1.00 10.74 C ANISOU 697 CB ARG C 150 1548 1358 1174 -157 322 -286 C ATOM 698 CG ARG C 150 -16.180 -20.851 3.235 1.00 12.45 C ANISOU 698 CG ARG C 150 1908 1582 1241 -205 212 -332 C ATOM 699 CD ARG C 150 -16.355 -21.687 1.992 1.00 14.35 C ANISOU 699 CD ARG C 150 2244 1846 1364 -248 148 -385 C ATOM 700 NE ARG C 150 -15.245 -21.483 1.069 1.00 16.02 N ANISOU 700 NE ARG C 150 2551 2063 1473 -236 187 -417 N ATOM 701 CZ ARG C 150 -14.674 -22.443 0.355 1.00 17.46 C ANISOU 701 CZ ARG C 150 2785 2224 1623 -197 280 -398 C ATOM 702 NH1 ARG C 150 -13.669 -22.146 -0.453 1.00 18.11 N ANISOU 702 NH1 ARG C 150 2895 2323 1664 -141 369 -365 N ATOM 703 NH2 ARG C 150 -15.102 -23.695 0.446 1.00 17.92 N ANISOU 703 NH2 ARG C 150 2874 2243 1692 -178 276 -414 N ATOM 704 N ASP C 151 -13.297 -22.507 6.434 1.00 9.07 N ANISOU 704 N ASP C 151 1118 1070 1259 -43 280 -310 N ATOM 705 CA ASP C 151 -11.969 -22.909 6.864 1.00 9.32 C ANISOU 705 CA ASP C 151 1134 1102 1306 44 273 -260 C ATOM 706 C ASP C 151 -11.849 -22.762 8.385 1.00 9.29 C ANISOU 706 C ASP C 151 1189 995 1347 17 264 -267 C ATOM 707 O ASP C 151 -12.744 -22.221 9.050 1.00 9.09 O ANISOU 707 O ASP C 151 1084 1017 1352 -7 318 -297 O ATOM 708 CB ASP C 151 -10.894 -22.114 6.104 1.00 9.69 C ANISOU 708 CB ASP C 151 1201 1187 1292 96 265 -222 C ATOM 709 CG ASP C 151 -10.924 -20.642 6.429 1.00 9.59 C ANISOU 709 CG ASP C 151 1193 1187 1263 53 179 -189 C ATOM 710 OD1 ASP C 151 -11.563 -19.857 5.690 1.00 9.83 O ANISOU 710 OD1 ASP C 151 1242 1253 1241 -28 106 -196 O ATOM 711 OD2 ASP C 151 -10.306 -20.278 7.449 1.00 10.06 O ANISOU 711 OD2 ASP C 151 1360 1168 1293 -56 84 -164 O ATOM 712 N ALA C 152 -10.747 -23.255 8.935 1.00 9.42 N ANISOU 712 N ALA C 152 1243 979 1357 117 227 -236 N ATOM 713 CA ALA C 152 -10.579 -23.313 10.380 1.00 9.67 C ANISOU 713 CA ALA C 152 1298 1023 1352 194 225 -188 C ATOM 714 C ALA C 152 -10.488 -21.938 11.029 1.00 8.62 C ANISOU 714 C ALA C 152 1037 998 1241 116 266 -175 C ATOM 715 O ALA C 152 -10.766 -21.803 12.223 1.00 8.57 O ANISOU 715 O ALA C 152 1064 986 1207 99 306 -54 O ATOM 716 CB ALA C 152 -9.354 -24.143 10.736 1.00 10.69 C ANISOU 716 CB ALA C 152 1489 1131 1442 335 200 -136 C ATOM 717 N SER C 153 -10.092 -20.927 10.264 1.00 8.05 N ANISOU 717 N SER C 153 911 981 1168 120 269 -167 N ATOM 718 CA SER C 153 -9.916 -19.597 10.847 1.00 7.64 C ANISOU 718 CA SER C 153 794 984 1124 -21 222 -117 C ATOM 719 C SER C 153 -11.230 -18.973 11.309 1.00 6.59 C ANISOU 719 C SER C 153 648 864 992 -23 181 -74 C ATOM 720 O SER C 153 -11.292 -18.382 12.390 1.00 6.35 O ANISOU 720 O SER C 153 720 775 916 -21 125 -86 O ATOM 721 CB SER C 153 -9.176 -18.647 9.893 1.00 8.53 C ANISOU 721 CB SER C 153 872 1176 1193 -88 266 -40 C ATOM 722 OG SER C 153 -10.015 -18.129 8.870 1.00 8.65 O ANISOU 722 OG SER C 153 1019 1073 1193 -114 283 -22 O ATOM 723 N GLY C 154 -12.270 -19.082 10.495 1.00 6.83 N ANISOU 723 N GLY C 154 702 938 956 -57 153 -89 N ATOM 724 CA GLY C 154 -13.543 -18.506 10.867 1.00 6.74 C ANISOU 724 CA GLY C 154 683 934 944 0 158 -94 C ATOM 725 C GLY C 154 -14.094 -19.180 12.111 1.00 6.26 C ANISOU 725 C GLY C 154 610 853 917 -41 87 -100 C ATOM 726 O GLY C 154 -14.697 -18.549 12.990 1.00 6.28 O ANISOU 726 O GLY C 154 679 816 892 -61 114 -80 O ATOM 727 N LEU C 155 -13.903 -20.494 12.178 1.00 6.54 N ANISOU 727 N LEU C 155 714 829 942 -95 98 -92 N ATOM 728 CA LEU C 155 -14.344 -21.269 13.331 1.00 6.65 C ANISOU 728 CA LEU C 155 814 722 990 -194 93 -126 C ATOM 729 C LEU C 155 -13.546 -20.894 14.585 1.00 6.35 C ANISOU 729 C LEU C 155 792 642 979 -120 110 -90 C ATOM 730 O LEU C 155 -14.113 -20.743 15.662 1.00 6.54 O ANISOU 730 O LEU C 155 860 653 971 -162 161 -126 O ATOM 731 CB LEU C 155 -14.242 -22.767 13.043 1.00 7.76 C ANISOU 731 CB LEU C 155 1075 753 1119 -226 95 -186 C ATOM 732 CG LEU C 155 -14.626 -23.653 14.225 1.00 8.65 C ANISOU 732 CG LEU C 155 1213 800 1272 -233 121 -148 C ATOM 733 CD1 LEU C 155 -16.062 -23.417 14.673 1.00 8.75 C ANISOU 733 CD1 LEU C 155 1094 908 1323 -284 145 -119 C ATOM 734 CD2 LEU C 155 -14.412 -25.127 13.888 1.00 9.96 C ANISOU 734 CD2 LEU C 155 1523 907 1354 -261 126 -152 C ATOM 735 N SER C 156 -12.233 -20.740 14.445 1.00 6.42 N ANISOU 735 N SER C 156 775 681 981 -58 53 -57 N ATOM 736 CA SER C 156 -11.396 -20.345 15.578 1.00 6.43 C ANISOU 736 CA SER C 156 729 723 992 -46 -5 -65 C ATOM 737 C SER C 156 -11.905 -19.040 16.191 1.00 5.82 C ANISOU 737 C SER C 156 610 702 901 -43 -31 -60 C ATOM 738 O SER C 156 -12.063 -18.903 17.414 1.00 6.44 O ANISOU 738 O SER C 156 811 727 909 -109 -8 -54 O ATOM 739 CB SER C 156 -9.947 -20.189 15.128 1.00 7.22 C ANISOU 739 CB SER C 156 796 830 1117 47 -55 -95 C ATOM 740 OG SER C 156 -9.151 -19.671 16.176 1.00 8.07 O ANISOU 740 OG SER C 156 922 923 1221 61 -131 -83 O ATOM 741 N ARG C 157 -12.174 -18.081 15.318 1.00 5.63 N ANISOU 741 N ARG C 157 575 708 856 -45 44 -42 N ATOM 742 CA ARG C 157 -12.635 -16.779 15.771 1.00 5.55 C ANISOU 742 CA ARG C 157 593 664 852 -70 89 -52 C ATOM 743 C ARG C 157 -14.027 -16.873 16.400 1.00 5.44 C ANISOU 743 C ARG C 157 627 623 818 -72 78 -26 C ATOM 744 O ARG C 157 -14.297 -16.240 17.426 1.00 5.74 O ANISOU 744 O ARG C 157 660 731 790 -78 127 -109 O ATOM 745 CB ARG C 157 -12.580 -15.798 14.612 1.00 5.87 C ANISOU 745 CB ARG C 157 662 704 865 -76 134 -33 C ATOM 746 CG ARG C 157 -11.157 -15.357 14.377 1.00 6.31 C ANISOU 746 CG ARG C 157 674 857 866 -95 165 -9 C ATOM 747 CD ARG C 157 -10.907 -14.839 13.004 1.00 6.86 C ANISOU 747 CD ARG C 157 621 1058 926 -100 230 38 C ATOM 748 NE ARG C 157 -9.607 -14.186 12.990 1.00 8.27 N ANISOU 748 NE ARG C 157 752 1290 1101 -39 300 239 N ATOM 749 CZ ARG C 157 -8.965 -13.834 11.890 1.00 9.28 C ANISOU 749 CZ ARG C 157 938 1321 1268 207 470 388 C ATOM 750 NH1 ARG C 157 -9.477 -14.135 10.705 1.00 10.33 N ANISOU 750 NH1 ARG C 157 1448 1233 1245 338 677 298 N ATOM 751 NH2 ARG C 157 -7.806 -13.193 11.982 1.00 10.41 N ANISOU 751 NH2 ARG C 157 1008 1520 1428 73 477 507 N ATOM 752 N HIS C 158 -14.908 -17.659 15.796 1.00 5.57 N ANISOU 752 N HIS C 158 588 669 860 -112 70 -57 N ATOM 753 CA HIS C 158 -16.259 -17.798 16.310 1.00 6.11 C ANISOU 753 CA HIS C 158 558 832 933 -198 58 -153 C ATOM 754 C HIS C 158 -16.261 -18.456 17.693 1.00 6.22 C ANISOU 754 C HIS C 158 640 790 936 -189 108 -124 C ATOM 755 O HIS C 158 -16.957 -18.007 18.603 1.00 6.69 O ANISOU 755 O HIS C 158 672 937 932 -149 180 -128 O ATOM 756 CB HIS C 158 -17.065 -18.611 15.298 1.00 6.94 C ANISOU 756 CB HIS C 158 619 966 1053 -206 76 -308 C ATOM 757 CG HIS C 158 -18.436 -18.981 15.764 1.00 7.50 C ANISOU 757 CG HIS C 158 624 1041 1185 -219 102 -397 C ATOM 758 ND1 HIS C 158 -19.508 -18.116 15.701 1.00 7.86 N ANISOU 758 ND1 HIS C 158 636 1131 1220 -60 89 -349 N ATOM 759 CD2 HIS C 158 -18.910 -20.127 16.305 1.00 8.17 C ANISOU 759 CD2 HIS C 158 712 1089 1304 -255 136 -444 C ATOM 760 CE1 HIS C 158 -20.583 -18.721 16.177 1.00 8.08 C ANISOU 760 CE1 HIS C 158 656 1147 1266 -110 160 -418 C ATOM 761 NE2 HIS C 158 -20.248 -19.942 16.547 1.00 8.43 N ANISOU 761 NE2 HIS C 158 697 1165 1342 -186 191 -480 N ATOM 762 N ARG C 159 -15.488 -19.529 17.850 1.00 6.46 N ANISOU 762 N ARG C 159 832 709 914 -165 189 -53 N ATOM 763 CA ARG C 159 -15.384 -20.192 19.153 1.00 7.43 C ANISOU 763 CA ARG C 159 1117 758 949 -193 182 -40 C ATOM 764 C ARG C 159 -14.887 -19.220 20.214 1.00 6.30 C ANISOU 764 C ARG C 159 772 730 894 -63 180 5 C ATOM 765 O ARG C 159 -15.431 -19.163 21.322 1.00 6.62 O ANISOU 765 O ARG C 159 767 866 881 -98 176 43 O ATOM 766 CB ARG C 159 -14.398 -21.367 19.100 1.00 9.99 C ANISOU 766 CB ARG C 159 1888 776 1130 -192 126 -15 C ATOM 767 CG ARG C 159 -14.807 -22.575 18.293 1.00 12.64 C ANISOU 767 CG ARG C 159 2531 909 1360 -204 119 -83 C ATOM 768 CD ARG C 159 -13.698 -23.662 18.328 1.00 15.11 C ANISOU 768 CD ARG C 159 3011 1157 1575 -44 87 -104 C ATOM 769 NE ARG C 159 -12.380 -23.169 17.922 1.00 17.76 N ANISOU 769 NE ARG C 159 3441 1539 1767 63 37 1 N ATOM 770 CZ ARG C 159 -11.446 -23.907 17.321 1.00 18.81 C ANISOU 770 CZ ARG C 159 3581 1687 1879 88 -6 37 C ATOM 771 NH1 ARG C 159 -10.270 -23.370 16.977 1.00 18.83 N ANISOU 771 NH1 ARG C 159 3611 1662 1881 151 -90 93 N ATOM 772 NH2 ARG C 159 -11.694 -25.179 17.045 1.00 19.75 N ANISOU 772 NH2 ARG C 159 3683 1856 1965 93 15 -8 N ATOM 773 N ARG C 160 -13.839 -18.473 19.886 1.00 5.96 N ANISOU 773 N ARG C 160 724 656 886 -40 112 0 N ATOM 774 CA ARG C 160 -13.306 -17.514 20.839 1.00 6.18 C ANISOU 774 CA ARG C 160 707 731 912 -47 150 3 C ATOM 775 C ARG C 160 -14.306 -16.412 21.169 1.00 5.98 C ANISOU 775 C ARG C 160 635 773 866 -81 146 -25 C ATOM 776 O ARG C 160 -14.326 -15.922 22.301 1.00 6.22 O ANISOU 776 O ARG C 160 726 801 838 -34 126 -87 O ATOM 777 CB ARG C 160 -11.990 -16.931 20.347 1.00 6.42 C ANISOU 777 CB ARG C 160 676 761 1002 -25 151 23 C ATOM 778 CG ARG C 160 -10.840 -17.918 20.447 1.00 7.22 C ANISOU 778 CG ARG C 160 758 854 1132 -14 173 22 C ATOM 779 CD ARG C 160 -9.636 -17.333 19.799 1.00 8.17 C ANISOU 779 CD ARG C 160 829 1003 1275 33 208 57 C ATOM 780 NE ARG C 160 -8.450 -18.143 19.978 1.00 8.66 N ANISOU 780 NE ARG C 160 775 1152 1365 -3 172 8 N ATOM 781 CZ ARG C 160 -7.214 -17.647 19.951 1.00 9.14 C ANISOU 781 CZ ARG C 160 836 1249 1387 46 181 -61 C ATOM 782 NH1 ARG C 160 -7.008 -16.334 19.846 1.00 9.14 N ANISOU 782 NH1 ARG C 160 916 1216 1343 -67 176 -80 N ATOM 783 NH2 ARG C 160 -6.175 -18.458 20.054 1.00 10.26 N ANISOU 783 NH2 ARG C 160 1032 1379 1486 102 112 -75 N ATOM 784 N ALA C 161 -15.138 -16.026 20.204 1.00 6.04 N ANISOU 784 N ALA C 161 709 749 835 14 137 36 N ATOM 785 CA ALA C 161 -16.181 -15.039 20.463 1.00 6.23 C ANISOU 785 CA ALA C 161 752 766 847 42 111 47 C ATOM 786 C ALA C 161 -17.212 -15.585 21.469 1.00 5.98 C ANISOU 786 C ALA C 161 679 768 825 -15 90 13 C ATOM 787 O ALA C 161 -17.629 -14.871 22.384 1.00 6.38 O ANISOU 787 O ALA C 161 819 759 846 83 143 -3 O ATOM 788 CB ALA C 161 -16.844 -14.582 19.164 1.00 7.08 C ANISOU 788 CB ALA C 161 945 890 856 79 118 100 C ATOM 789 N HIS C 162 -17.617 -16.847 21.330 1.00 5.90 N ANISOU 789 N HIS C 162 671 752 819 46 80 0 N ATOM 790 CA HIS C 162 -18.488 -17.432 22.360 1.00 5.86 C ANISOU 790 CA HIS C 162 608 723 895 61 81 -26 C ATOM 791 C HIS C 162 -17.803 -17.389 23.734 1.00 5.17 C ANISOU 791 C HIS C 162 494 644 828 -62 93 70 C ATOM 792 O HIS C 162 -18.468 -17.196 24.742 1.00 5.90 O ANISOU 792 O HIS C 162 533 855 854 -16 107 56 O ATOM 793 CB HIS C 162 -18.821 -18.910 22.103 1.00 6.67 C ANISOU 793 CB HIS C 162 712 783 1039 -63 15 -134 C ATOM 794 CG HIS C 162 -19.868 -19.202 21.058 1.00 6.91 C ANISOU 794 CG HIS C 162 632 860 1134 -111 41 -194 C ATOM 795 ND1 HIS C 162 -21.176 -18.766 21.131 1.00 6.98 N ANISOU 795 ND1 HIS C 162 617 927 1107 -31 36 -172 N ATOM 796 CD2 HIS C 162 -19.819 -20.042 19.995 1.00 7.85 C ANISOU 796 CD2 HIS C 162 760 983 1239 -132 3 -295 C ATOM 797 CE1 HIS C 162 -21.867 -19.288 20.127 1.00 7.07 C ANISOU 797 CE1 HIS C 162 732 807 1146 -59 86 -234 C ATOM 798 NE2 HIS C 162 -21.067 -20.065 19.423 1.00 7.90 N ANISOU 798 NE2 HIS C 162 776 980 1248 -143 98 -305 N ATOM 799 N LEU C 163 -16.494 -17.637 23.779 1.00 5.38 N ANISOU 799 N LEU C 163 572 674 799 -24 40 57 N ATOM 800 CA LEU C 163 -15.758 -17.670 25.048 1.00 5.78 C ANISOU 800 CA LEU C 163 629 700 868 -52 37 67 C ATOM 801 C LEU C 163 -15.494 -16.287 25.625 1.00 5.90 C ANISOU 801 C LEU C 163 638 733 871 -18 33 39 C ATOM 802 O LEU C 163 -15.117 -16.167 26.793 1.00 7.20 O ANISOU 802 O LEU C 163 1091 783 863 -12 -68 55 O ATOM 803 CB LEU C 163 -14.412 -18.356 24.879 1.00 5.88 C ANISOU 803 CB LEU C 163 579 706 949 -4 24 57 C ATOM 804 CG LEU C 163 -14.425 -19.857 24.607 1.00 6.64 C ANISOU 804 CG LEU C 163 666 834 1023 73 41 6 C ATOM 805 CD1 LEU C 163 -12.996 -20.346 24.523 1.00 7.67 C ANISOU 805 CD1 LEU C 163 851 970 1093 231 43 11 C ATOM 806 CD2 LEU C 163 -15.195 -20.615 25.686 1.00 6.81 C ANISOU 806 CD2 LEU C 163 738 786 1065 -16 39 54 C ATOM 807 N GLY C 164 -15.655 -15.243 24.817 1.00 5.85 N ANISOU 807 N GLY C 164 601 691 929 -9 90 5 N ATOM 808 CA GLY C 164 -15.232 -13.913 25.228 1.00 6.42 C ANISOU 808 CA GLY C 164 736 716 986 -34 99 -12 C ATOM 809 C GLY C 164 -13.717 -13.761 25.315 1.00 6.54 C ANISOU 809 C GLY C 164 742 712 1033 -134 92 7 C ATOM 810 O GLY C 164 -13.223 -12.934 26.073 1.00 7.48 O ANISOU 810 O GLY C 164 937 774 1133 -204 26 -121 O ATOM 811 N TYR C 165 -12.982 -14.555 24.541 1.00 6.15 N ANISOU 811 N TYR C 165 640 685 1010 -115 60 30 N ATOM 812 CA TYR C 165 -11.527 -14.519 24.580 1.00 6.25 C ANISOU 812 CA TYR C 165 677 685 1012 -61 6 104 C ATOM 813 C TYR C 165 -11.024 -13.399 23.667 1.00 5.88 C ANISOU 813 C TYR C 165 671 641 923 -92 -31 72 C ATOM 814 O TYR C 165 -11.006 -13.530 22.436 1.00 6.22 O ANISOU 814 O TYR C 165 800 643 921 -112 -73 84 O ATOM 815 CB TYR C 165 -10.917 -15.875 24.201 1.00 6.71 C ANISOU 815 CB TYR C 165 709 736 1105 -75 -52 124 C ATOM 816 CG TYR C 165 -9.416 -15.884 24.367 1.00 7.13 C ANISOU 816 CG TYR C 165 780 794 1134 -47 -58 173 C ATOM 817 CD1 TYR C 165 -8.570 -16.041 23.276 1.00 7.95 C ANISOU 817 CD1 TYR C 165 841 943 1235 -15 33 117 C ATOM 818 CD2 TYR C 165 -8.836 -15.696 25.620 1.00 8.06 C ANISOU 818 CD2 TYR C 165 864 1020 1180 -14 -120 177 C ATOM 819 CE1 TYR C 165 -7.196 -16.043 23.426 1.00 8.48 C ANISOU 819 CE1 TYR C 165 882 1019 1323 85 0 123 C ATOM 820 CE2 TYR C 165 -7.458 -15.686 25.780 1.00 8.81 C ANISOU 820 CE2 TYR C 165 916 1165 1267 30 -116 170 C ATOM 821 CZ TYR C 165 -6.642 -15.855 24.676 1.00 8.61 C ANISOU 821 CZ TYR C 165 781 1126 1365 105 -59 182 C ATOM 822 OH TYR C 165 -5.275 -15.843 24.820 1.00 10.03 O ANISOU 822 OH TYR C 165 893 1418 1500 117 -145 177 O ATOM 823 N ARG C 166 -10.648 -12.293 24.310 1.00 5.81 N ANISOU 823 N ARG C 166 676 636 898 -94 -5 87 N ATOM 824 CA ARG C 166 -10.258 -11.056 23.638 1.00 6.03 C ANISOU 824 CA ARG C 166 690 634 966 -104 31 86 C ATOM 825 C ARG C 166 -8.974 -10.579 24.315 1.00 6.41 C ANISOU 825 C ARG C 166 775 653 1007 -121 6 59 C ATOM 826 O ARG C 166 -8.997 -9.688 25.168 1.00 7.02 O ANISOU 826 O ARG C 166 896 730 1041 -139 -22 -11 O ATOM 827 CB ARG C 166 -11.389 -10.027 23.748 1.00 6.46 C ANISOU 827 CB ARG C 166 738 694 1023 -80 -22 91 C ATOM 828 CG ARG C 166 -12.644 -10.444 22.973 1.00 6.81 C ANISOU 828 CG ARG C 166 815 698 1074 29 -28 87 C ATOM 829 CD ARG C 166 -13.844 -9.525 23.175 1.00 7.66 C ANISOU 829 CD ARG C 166 919 863 1128 68 -56 106 C ATOM 830 NE ARG C 166 -13.689 -8.210 22.566 1.00 8.17 N ANISOU 830 NE ARG C 166 987 928 1191 -77 -91 95 N ATOM 831 CZ ARG C 166 -14.218 -7.825 21.410 1.00 8.67 C ANISOU 831 CZ ARG C 166 1024 1012 1259 -71 -141 150 C ATOM 832 NH1 ARG C 166 -14.029 -6.595 20.993 1.00 8.84 N ANISOU 832 NH1 ARG C 166 1022 1050 1286 -27 -178 159 N ATOM 833 NH2 ARG C 166 -14.939 -8.645 20.672 1.00 10.05 N ANISOU 833 NH2 ARG C 166 1335 1149 1335 -166 -239 192 N ATOM 834 N PRO C 167 -7.847 -11.202 23.951 1.00 6.68 N ANISOU 834 N PRO C 167 700 735 1105 -194 -2 61 N ATOM 835 CA PRO C 167 -6.628 -11.055 24.754 1.00 7.56 C ANISOU 835 CA PRO C 167 811 868 1196 -161 -127 162 C ATOM 836 C PRO C 167 -5.802 -9.806 24.463 1.00 7.80 C ANISOU 836 C PRO C 167 778 951 1236 -168 -196 202 C ATOM 837 O PRO C 167 -4.848 -9.549 25.194 1.00 9.61 O ANISOU 837 O PRO C 167 1088 1222 1343 -345 -361 327 O ATOM 838 CB PRO C 167 -5.823 -12.303 24.376 1.00 8.01 C ANISOU 838 CB PRO C 167 868 922 1253 -2 -50 137 C ATOM 839 CG PRO C 167 -6.230 -12.577 22.965 1.00 7.76 C ANISOU 839 CG PRO C 167 856 842 1249 19 58 101 C ATOM 840 CD PRO C 167 -7.709 -12.263 22.935 1.00 7.09 C ANISOU 840 CD PRO C 167 766 754 1173 6 88 41 C ATOM 841 N ARG C 168 -6.133 -9.067 23.409 1.00 7.17 N ANISOU 841 N ARG C 168 748 786 1190 -169 -116 107 N ATOM 842 CA ARG C 168 -5.351 -7.891 23.034 1.00 7.41 C ANISOU 842 CA ARG C 168 722 794 1299 -107 -101 0 C ATOM 843 C ARG C 168 -6.128 -6.623 23.346 1.00 8.03 C ANISOU 843 C ARG C 168 717 857 1478 -87 -124 -134 C ATOM 844 O ARG C 168 -7.292 -6.499 23.002 1.00 9.77 O ANISOU 844 O ARG C 168 915 1142 1656 35 -212 -373 O ATOM 845 CB ARG C 168 -4.970 -7.948 21.556 1.00 7.86 C ANISOU 845 CB ARG C 168 777 886 1325 -40 -27 41 C ATOM 846 CG ARG C 168 -4.107 -9.168 21.220 1.00 9.28 C ANISOU 846 CG ARG C 168 987 1113 1427 -34 3 19 C ATOM 847 CD ARG C 168 -2.597 -8.955 21.460 1.00 10.99 C ANISOU 847 CD ARG C 168 1176 1456 1542 56 -29 19 C ATOM 848 NE ARG C 168 -2.175 -8.625 22.828 1.00 11.89 N ANISOU 848 NE ARG C 168 1180 1695 1645 -1 -17 -16 N ATOM 849 CZ ARG C 168 -1.863 -9.511 23.773 1.00 12.83 C ANISOU 849 CZ ARG C 168 1293 1881 1701 -14 -49 -76 C ATOM 850 NH1 ARG C 168 -1.454 -9.085 24.965 1.00 13.51 N ANISOU 850 NH1 ARG C 168 1356 2029 1748 -110 -82 -93 N ATOM 851 NH2 ARG C 168 -1.963 -10.814 23.539 1.00 13.28 N ANISOU 851 NH2 ARG C 168 1419 1913 1713 45 -37 -45 N ATOM 852 N SER C 169 -5.495 -5.666 23.996 1.00 9.32 N ANISOU 852 N SER C 169 1068 881 1592 -77 -189 -137 N ATOM 853 CA SER C 169 -6.224 -4.477 24.397 1.00 10.12 C ANISOU 853 CA SER C 169 1323 898 1624 20 -129 -69 C ATOM 854 C SER C 169 -5.647 -3.205 23.812 1.00 8.73 C ANISOU 854 C SER C 169 1016 819 1481 -105 -257 -66 C ATOM 855 O SER C 169 -4.455 -3.101 23.506 1.00 9.64 O ANISOU 855 O SER C 169 1143 937 1584 -74 -256 57 O ATOM 856 CB SER C 169 -6.268 -4.378 25.911 1.00 12.84 C ANISOU 856 CB SER C 169 2004 1133 1743 92 -49 7 C ATOM 857 OG SER C 169 -4.960 -4.372 26.424 1.00 14.98 O ANISOU 857 OG SER C 169 2531 1347 1815 41 -60 7 O ATOM 858 N CYS C 170 -6.522 -2.228 23.655 1.00 8.06 N ANISOU 858 N CYS C 170 1062 741 1258 -71 -250 -75 N ATOM 859 CA CYS C 170 -6.097 -0.900 23.281 1.00 7.50 C ANISOU 859 CA CYS C 170 1027 745 1079 -157 -248 -54 C ATOM 860 C CYS C 170 -5.296 -0.281 24.426 1.00 7.83 C ANISOU 860 C CYS C 170 1109 804 1061 -106 -297 15 C ATOM 861 O CYS C 170 -5.789 -0.201 25.548 1.00 8.44 O ANISOU 861 O CYS C 170 1361 862 984 -150 -303 17 O ATOM 862 CB CYS C 170 -7.321 -0.047 23.022 1.00 7.06 C ANISOU 862 CB CYS C 170 974 726 983 -117 -235 -39 C ATOM 863 SG CYS C 170 -6.879 1.665 22.604 1.00 6.72 S ANISOU 863 SG CYS C 170 939 744 869 -154 -220 -35 S ATOM 864 N PRO C 171 -4.065 0.179 24.154 1.00 8.26 N ANISOU 864 N PRO C 171 1072 908 1159 -115 -376 3 N ATOM 865 CA PRO C 171 -3.279 0.764 25.246 1.00 9.02 C ANISOU 865 CA PRO C 171 1207 982 1238 -156 -500 -21 C ATOM 866 C PRO C 171 -3.820 2.118 25.679 1.00 9.06 C ANISOU 866 C PRO C 171 1312 904 1226 -170 -602 7 C ATOM 867 O PRO C 171 -3.538 2.577 26.793 1.00 9.52 O ANISOU 867 O PRO C 171 1421 954 1241 -44 -625 -12 O ATOM 868 CB PRO C 171 -1.879 0.892 24.641 1.00 9.90 C ANISOU 868 CB PRO C 171 1291 1142 1329 -80 -404 -9 C ATOM 869 CG PRO C 171 -2.114 1.000 23.181 1.00 9.94 C ANISOU 869 CG PRO C 171 1220 1228 1329 -113 -310 16 C ATOM 870 CD PRO C 171 -3.306 0.117 22.892 1.00 9.10 C ANISOU 870 CD PRO C 171 1100 1107 1251 -113 -284 5 C ATOM 871 N GLU C 172 -4.594 2.760 24.823 1.00 9.26 N ANISOU 871 N GLU C 172 1428 843 1249 -146 -639 31 N ATOM 872 CA AGLU C 172 -5.155 4.056 25.164 0.48 9.60 C ANISOU 872 CA AGLU C 172 1533 875 1239 -165 -656 0 C ATOM 873 CA BGLU C 172 -5.134 4.053 25.176 0.52 9.89 C ANISOU 873 CA BGLU C 172 1615 885 1260 -211 -651 12 C ATOM 874 C GLU C 172 -6.308 3.927 26.159 1.00 10.26 C ANISOU 874 C GLU C 172 1802 910 1187 -119 -573 -124 C ATOM 875 O GLU C 172 -6.298 4.560 27.218 1.00 12.23 O ANISOU 875 O GLU C 172 2154 1205 1288 -119 -517 -389 O ATOM 876 CB AGLU C 172 -5.619 4.771 23.897 0.48 9.82 C ANISOU 876 CB AGLU C 172 1553 902 1277 -154 -663 64 C ATOM 877 CB BGLU C 172 -5.525 4.811 23.909 0.52 10.72 C ANISOU 877 CB BGLU C 172 1804 927 1341 -293 -642 99 C ATOM 878 CG AGLU C 172 -6.359 6.062 24.153 0.48 10.09 C ANISOU 878 CG AGLU C 172 1617 924 1294 -142 -640 38 C ATOM 879 CG BGLU C 172 -5.494 6.305 24.067 0.52 11.80 C ANISOU 879 CG BGLU C 172 2114 967 1404 -319 -579 124 C ATOM 880 CD AGLU C 172 -5.492 7.087 24.830 0.48 10.16 C ANISOU 880 CD AGLU C 172 1656 930 1275 -128 -620 -13 C ATOM 881 CD BGLU C 172 -6.472 6.762 25.107 0.52 12.68 C ANISOU 881 CD BGLU C 172 2387 991 1438 -296 -568 156 C ATOM 882 OE1AGLU C 172 -4.260 7.080 24.612 0.48 9.89 O ANISOU 882 OE1AGLU C 172 1601 876 1279 -41 -614 -76 O ATOM 883 OE1BGLU C 172 -7.617 6.261 25.092 0.52 12.94 O ANISOU 883 OE1BGLU C 172 2465 995 1457 -237 -527 132 O ATOM 884 OE2AGLU C 172 -6.044 7.910 25.579 0.48 10.36 O ANISOU 884 OE2AGLU C 172 1713 970 1253 -146 -569 -1 O ATOM 885 OE2BGLU C 172 -6.090 7.594 25.949 0.52 13.03 O ANISOU 885 OE2BGLU C 172 2507 1001 1445 -364 -629 173 O ATOM 886 N CYS C 173 -7.295 3.091 25.829 1.00 9.49 N ANISOU 886 N CYS C 173 1769 826 1011 -137 -340 -159 N ATOM 887 CA CYS C 173 -8.548 3.034 26.596 1.00 9.49 C ANISOU 887 CA CYS C 173 1844 840 923 -109 -146 -186 C ATOM 888 C CYS C 173 -8.822 1.714 27.302 1.00 9.93 C ANISOU 888 C CYS C 173 1929 928 917 -81 -33 -161 C ATOM 889 O CYS C 173 -9.752 1.621 28.098 1.00 10.79 O ANISOU 889 O CYS C 173 2107 1013 980 -90 107 -85 O ATOM 890 CB CYS C 173 -9.758 3.407 25.727 1.00 9.06 C ANISOU 890 CB CYS C 173 1736 809 896 -60 -28 -166 C ATOM 891 SG CYS C 173 -10.222 2.132 24.509 1.00 8.16 S ANISOU 891 SG CYS C 173 1441 794 864 -133 110 -116 S ATOM 892 N GLY C 174 -8.033 0.689 27.004 1.00 9.58 N ANISOU 892 N GLY C 174 1842 888 912 -110 -85 -80 N ATOM 893 CA GLY C 174 -8.195 -0.605 27.646 1.00 10.12 C ANISOU 893 CA GLY C 174 1881 936 1028 -159 -74 -41 C ATOM 894 C GLY C 174 -9.203 -1.536 26.998 1.00 10.23 C ANISOU 894 C GLY C 174 1838 915 1134 -130 -54 -20 C ATOM 895 O GLY C 174 -9.334 -2.682 27.414 1.00 11.28 O ANISOU 895 O GLY C 174 2083 980 1222 -134 -103 96 O ATOM 896 N LYS C 175 -9.922 -1.080 25.981 1.00 9.50 N ANISOU 896 N LYS C 175 1633 833 1142 -91 27 -121 N ATOM 897 CA ALYS C 175 -10.906 -1.946 25.351 0.58 9.14 C ANISOU 897 CA ALYS C 175 1468 836 1169 -56 54 -138 C ATOM 898 CA BLYS C 175 -10.906 -1.931 25.315 0.42 9.14 C ANISOU 898 CA BLYS C 175 1474 830 1168 -18 70 -142 C ATOM 899 C LYS C 175 -10.227 -3.159 24.718 1.00 8.53 C ANISOU 899 C LYS C 175 1311 787 1144 -48 76 -116 C ATOM 900 O LYS C 175 -9.192 -3.041 24.052 1.00 8.70 O ANISOU 900 O LYS C 175 1221 840 1244 -119 142 -78 O ATOM 901 CB ALYS C 175 -11.727 -1.188 24.316 0.58 9.88 C ANISOU 901 CB ALYS C 175 1537 998 1219 -42 65 -136 C ATOM 902 CB BLYS C 175 -11.646 -1.161 24.219 0.42 9.75 C ANISOU 902 CB BLYS C 175 1534 956 1215 76 113 -156 C ATOM 903 CG ALYS C 175 -12.900 -1.987 23.805 0.58 10.97 C ANISOU 903 CG ALYS C 175 1632 1270 1264 -44 68 -78 C ATOM 904 CG BLYS C 175 -12.675 -1.997 23.467 0.42 10.58 C ANISOU 904 CG BLYS C 175 1598 1164 1260 140 165 -127 C ATOM 905 CD ALYS C 175 -13.875 -1.107 23.049 0.58 11.69 C ANISOU 905 CD ALYS C 175 1677 1473 1292 -106 71 -13 C ATOM 906 CD BLYS C 175 -13.505 -1.149 22.510 0.42 11.34 C ANISOU 906 CD BLYS C 175 1696 1322 1291 136 165 -116 C ATOM 907 CE ALYS C 175 -15.052 -1.919 22.536 0.58 12.48 C ANISOU 907 CE ALYS C 175 1775 1636 1332 -162 100 27 C ATOM 908 CE BLYS C 175 -14.682 -1.935 21.940 0.42 12.06 C ANISOU 908 CE BLYS C 175 1825 1438 1321 55 195 -85 C ATOM 909 NZ ALYS C 175 -16.129 -1.064 21.967 0.58 12.92 N ANISOU 909 NZ ALYS C 175 1814 1735 1362 -202 79 34 N ATOM 910 NZ BLYS C 175 -15.630 -2.387 23.005 0.42 12.48 N ANISOU 910 NZ BLYS C 175 1900 1497 1346 -18 192 -57 N ATOM 911 N CYS C 176 -10.825 -4.331 24.931 1.00 7.73 N ANISOU 911 N CYS C 176 1193 704 1040 -71 53 -105 N ATOM 912 CA ACYS C 176 -10.241 -5.587 24.474 0.82 8.02 C ANISOU 912 CA ACYS C 176 1351 721 975 -36 -88 -96 C ATOM 913 CA BCYS C 176 -10.241 -5.592 24.485 0.18 7.39 C ANISOU 913 CA BCYS C 176 1093 721 995 -93 61 -94 C ATOM 914 C CYS C 176 -10.810 -6.045 23.144 1.00 6.51 C ANISOU 914 C CYS C 176 886 660 928 -125 27 -92 C ATOM 915 O CYS C 176 -11.994 -5.827 22.852 1.00 7.05 O ANISOU 915 O CYS C 176 801 926 952 -26 66 -144 O ATOM 916 CB ACYS C 176 -10.442 -6.674 25.525 0.82 10.72 C ANISOU 916 CB ACYS C 176 2144 921 1010 11 -299 -47 C ATOM 917 CB BCYS C 176 -10.465 -6.690 25.528 0.18 8.21 C ANISOU 917 CB BCYS C 176 1256 832 1031 -102 115 -71 C ATOM 918 SG ACYS C 176 -9.571 -6.304 27.062 0.82 13.61 S ANISOU 918 SG ACYS C 176 2934 1130 1107 41 -517 -27 S ATOM 919 SG BCYS C 176 -12.192 -7.204 25.695 0.18 9.08 S ANISOU 919 SG BCYS C 176 1417 949 1083 -121 156 -55 S ATOM 920 N PHE C 177 -9.952 -6.697 22.359 1.00 6.07 N ANISOU 920 N PHE C 177 752 668 885 -131 23 -91 N ATOM 921 CA PHE C 177 -10.282 -7.207 21.038 1.00 6.23 C ANISOU 921 CA PHE C 177 739 739 888 -94 101 -43 C ATOM 922 C PHE C 177 -9.651 -8.582 20.837 1.00 5.77 C ANISOU 922 C PHE C 177 652 679 860 -144 81 -31 C ATOM 923 O PHE C 177 -8.786 -9.022 21.602 1.00 5.98 O ANISOU 923 O PHE C 177 769 645 858 -105 21 -73 O ATOM 924 CB PHE C 177 -9.797 -6.240 19.938 1.00 7.23 C ANISOU 924 CB PHE C 177 942 802 1002 -43 205 45 C ATOM 925 CG PHE C 177 -10.557 -4.941 19.901 1.00 8.00 C ANISOU 925 CG PHE C 177 989 952 1100 -106 235 163 C ATOM 926 CD1 PHE C 177 -11.712 -4.824 19.142 1.00 9.08 C ANISOU 926 CD1 PHE C 177 1144 1130 1175 22 107 249 C ATOM 927 CD2 PHE C 177 -10.128 -3.847 20.637 1.00 8.20 C ANISOU 927 CD2 PHE C 177 995 930 1190 -165 283 147 C ATOM 928 CE1 PHE C 177 -12.426 -3.646 19.113 1.00 9.59 C ANISOU 928 CE1 PHE C 177 1184 1194 1267 -17 46 289 C ATOM 929 CE2 PHE C 177 -10.848 -2.659 20.609 1.00 8.88 C ANISOU 929 CE2 PHE C 177 1111 994 1269 -97 229 213 C ATOM 930 CZ PHE C 177 -11.992 -2.571 19.847 1.00 9.18 C ANISOU 930 CZ PHE C 177 1072 1109 1306 -51 140 248 C ATOM 931 N ARG C 178 -10.080 -9.254 19.779 1.00 6.05 N ANISOU 931 N ARG C 178 724 701 875 -117 66 -113 N ATOM 932 CA ARG C 178 -9.659 -10.631 19.562 1.00 6.01 C ANISOU 932 CA ARG C 178 700 728 856 -186 56 -109 C ATOM 933 C ARG C 178 -8.187 -10.760 19.183 1.00 5.93 C ANISOU 933 C ARG C 178 704 692 856 -109 76 -66 C ATOM 934 O ARG C 178 -7.573 -11.803 19.439 1.00 6.58 O ANISOU 934 O ARG C 178 858 715 925 -40 160 -19 O ATOM 935 CB ARG C 178 -10.510 -11.277 18.467 1.00 6.55 C ANISOU 935 CB ARG C 178 798 840 849 -223 29 -116 C ATOM 936 CG ARG C 178 -10.140 -10.830 17.071 1.00 7.23 C ANISOU 936 CG ARG C 178 978 909 859 -245 -14 -101 C ATOM 937 CD ARG C 178 -11.082 -11.375 16.019 1.00 7.32 C ANISOU 937 CD ARG C 178 957 982 841 -272 -14 -109 C ATOM 938 NE ARG C 178 -10.554 -11.077 14.695 1.00 7.48 N ANISOU 938 NE ARG C 178 902 1081 860 -216 -24 -121 N ATOM 939 CZ ARG C 178 -11.224 -11.226 13.558 1.00 7.36 C ANISOU 939 CZ ARG C 178 879 1017 901 -119 -35 -168 C ATOM 940 NH1 ARG C 178 -12.478 -11.652 13.566 1.00 6.94 N ANISOU 940 NH1 ARG C 178 794 910 933 27 -46 -191 N ATOM 941 NH2 ARG C 178 -10.619 -10.934 12.415 1.00 8.36 N ANISOU 941 NH2 ARG C 178 1036 1222 917 -159 -34 -98 N ATOM 942 N ASP C 179 -7.631 -9.732 18.542 1.00 6.10 N ANISOU 942 N ASP C 179 687 762 867 -166 66 -84 N ATOM 943 CA ASP C 179 -6.284 -9.800 18.001 1.00 6.14 C ANISOU 943 CA ASP C 179 690 760 883 -93 73 -106 C ATOM 944 C ASP C 179 -5.736 -8.378 17.822 1.00 5.87 C ANISOU 944 C ASP C 179 648 688 894 -121 35 -107 C ATOM 945 O ASP C 179 -6.463 -7.386 17.969 1.00 6.07 O ANISOU 945 O ASP C 179 693 694 920 -128 44 -101 O ATOM 946 CB ASP C 179 -6.207 -10.653 16.707 1.00 6.27 C ANISOU 946 CB ASP C 179 713 762 907 -96 103 -85 C ATOM 947 CG ASP C 179 -7.069 -10.128 15.572 1.00 6.46 C ANISOU 947 CG ASP C 179 759 778 920 -162 76 -103 C ATOM 948 OD1 ASP C 179 -7.566 -10.973 14.778 1.00 7.44 O ANISOU 948 OD1 ASP C 179 962 933 930 -132 88 -183 O ATOM 949 OD2 ASP C 179 -7.232 -8.895 15.458 1.00 7.46 O ANISOU 949 OD2 ASP C 179 1001 832 1000 -92 -10 -59 O ATOM 950 N GLN C 180 -4.444 -8.299 17.534 1.00 6.27 N ANISOU 950 N GLN C 180 612 781 992 -126 60 -59 N ATOM 951 CA GLN C 180 -3.781 -7.013 17.436 1.00 6.63 C ANISOU 951 CA GLN C 180 612 805 1101 -202 57 -54 C ATOM 952 C GLN C 180 -4.288 -6.220 16.240 1.00 6.34 C ANISOU 952 C GLN C 180 619 725 1063 -133 132 -51 C ATOM 953 O GLN C 180 -4.367 -4.994 16.312 1.00 6.89 O ANISOU 953 O GLN C 180 744 713 1162 -127 119 -59 O ATOM 954 CB GLN C 180 -2.265 -7.193 17.372 1.00 7.58 C ANISOU 954 CB GLN C 180 634 1005 1243 -273 4 -37 C ATOM 955 CG GLN C 180 -1.516 -5.878 17.471 1.00 8.83 C ANISOU 955 CG GLN C 180 839 1170 1347 -298 -56 -73 C ATOM 956 CD GLN C 180 -1.754 -5.196 18.799 1.00 10.51 C ANISOU 956 CD GLN C 180 1269 1312 1410 -410 -167 -111 C ATOM 957 OE1 GLN C 180 -1.652 -5.822 19.853 1.00 12.78 O ANISOU 957 OE1 GLN C 180 1961 1444 1450 -483 -283 -67 O ATOM 958 NE2 GLN C 180 -2.073 -3.908 18.760 1.00 10.57 N ANISOU 958 NE2 GLN C 180 1202 1357 1458 -285 -147 -226 N ATOM 959 N SER C 181 -4.625 -6.889 15.139 1.00 6.67 N ANISOU 959 N SER C 181 782 795 957 -10 134 -34 N ATOM 960 CA ASER C 181 -5.178 -6.214 13.963 0.41 6.91 C ANISOU 960 CA ASER C 181 871 818 936 -22 132 8 C ATOM 961 CA BSER C 181 -5.097 -6.111 14.009 0.34 7.10 C ANISOU 961 CA BSER C 181 995 773 929 12 107 -47 C ATOM 962 CA CSER C 181 -5.174 -6.221 13.960 0.25 6.82 C ANISOU 962 CA CSER C 181 879 782 932 -43 115 -24 C ATOM 963 C SER C 181 -6.436 -5.436 14.302 1.00 6.42 C ANISOU 963 C SER C 181 823 726 890 -91 29 -58 C ATOM 964 O SER C 181 -6.646 -4.313 13.833 1.00 6.52 O ANISOU 964 O SER C 181 907 719 851 -106 -16 -14 O ATOM 965 CB ASER C 181 -5.501 -7.236 12.866 0.41 7.27 C ANISOU 965 CB ASER C 181 903 904 957 -45 161 43 C ATOM 966 CB BSER C 181 -5.112 -6.916 12.706 0.34 8.10 C ANISOU 966 CB BSER C 181 1286 849 944 30 117 -57 C ATOM 967 CB CSER C 181 -5.494 -7.252 12.868 0.25 7.18 C ANISOU 967 CB CSER C 181 977 802 950 -82 135 -28 C ATOM 968 OG ASER C 181 -4.310 -7.766 12.328 0.41 7.60 O ANISOU 968 OG ASER C 181 964 956 966 54 151 45 O ATOM 969 OG BSER C 181 -5.736 -8.163 12.884 0.34 8.49 O ANISOU 969 OG BSER C 181 1393 882 952 -11 49 -81 O ATOM 970 OG CSER C 181 -6.134 -6.641 11.762 0.25 7.55 O ANISOU 970 OG CSER C 181 1102 804 962 -58 131 -54 O ATOM 971 N GLU C 182 -7.301 -6.051 15.104 1.00 6.14 N ANISOU 971 N GLU C 182 763 678 891 -125 -49 -62 N ATOM 972 CA AGLU C 182 -8.538 -5.393 15.515 0.66 5.75 C ANISOU 972 CA AGLU C 182 615 669 900 -164 -25 -43 C ATOM 973 CA BGLU C 182 -8.529 -5.375 15.473 0.34 6.09 C ANISOU 973 CA BGLU C 182 697 711 907 -140 -48 -38 C ATOM 974 C GLU C 182 -8.256 -4.228 16.455 1.00 5.79 C ANISOU 974 C GLU C 182 609 711 878 -154 -6 -25 C ATOM 975 O GLU C 182 -8.901 -3.186 16.361 1.00 5.81 O ANISOU 975 O GLU C 182 638 655 915 -110 -44 -29 O ATOM 976 CB AGLU C 182 -9.509 -6.385 16.162 0.66 6.37 C ANISOU 976 CB AGLU C 182 719 739 962 -216 -57 -9 C ATOM 977 CB BGLU C 182 -9.571 -6.370 15.984 0.34 6.92 C ANISOU 977 CB BGLU C 182 843 815 973 -125 -111 -5 C ATOM 978 CG AGLU C 182 -10.391 -7.125 15.162 0.66 6.83 C ANISOU 978 CG AGLU C 182 807 804 983 -185 -100 -21 C ATOM 979 CG BGLU C 182 -9.883 -7.471 14.972 0.34 7.75 C ANISOU 979 CG BGLU C 182 987 930 1026 -114 -145 -37 C ATOM 980 CD AGLU C 182 -11.297 -6.187 14.376 0.66 7.37 C ANISOU 980 CD AGLU C 182 875 954 970 -172 -70 -22 C ATOM 981 CD BGLU C 182 -10.289 -6.928 13.618 0.34 8.78 C ANISOU 981 CD BGLU C 182 1189 1088 1061 -37 -147 -68 C ATOM 982 OE1AGLU C 182 -11.194 -6.185 13.120 0.66 7.89 O ANISOU 982 OE1AGLU C 182 942 1094 962 -90 -88 30 O ATOM 983 OE1BGLU C 182 -11.338 -6.254 13.536 0.34 9.35 O ANISOU 983 OE1BGLU C 182 1325 1136 1091 -18 -178 -25 O ATOM 984 OE2AGLU C 182 -12.125 -5.479 15.015 0.66 8.14 O ANISOU 984 OE2AGLU C 182 1033 1032 1029 -201 -127 6 O ATOM 985 OE2BGLU C 182 -9.563 -7.184 12.633 0.34 9.55 O ANISOU 985 OE2BGLU C 182 1332 1230 1068 2 -125 -89 O ATOM 986 N VAL C 183 -7.301 -4.396 17.375 1.00 5.58 N ANISOU 986 N VAL C 183 586 715 818 -198 18 -55 N ATOM 987 CA VAL C 183 -6.887 -3.248 18.187 1.00 5.76 C ANISOU 987 CA VAL C 183 627 725 836 -155 -21 -84 C ATOM 988 C VAL C 183 -6.434 -2.103 17.270 1.00 5.56 C ANISOU 988 C VAL C 183 572 687 855 -163 -71 -99 C ATOM 989 O VAL C 183 -6.852 -0.952 17.431 1.00 5.89 O ANISOU 989 O VAL C 183 721 644 871 -126 -29 -77 O ATOM 990 CB VAL C 183 -5.743 -3.594 19.162 1.00 6.26 C ANISOU 990 CB VAL C 183 718 798 860 -154 -49 -65 C ATOM 991 CG1 VAL C 183 -5.227 -2.327 19.842 1.00 7.11 C ANISOU 991 CG1 VAL C 183 978 849 874 -64 -133 -95 C ATOM 992 CG2 VAL C 183 -6.205 -4.613 20.207 1.00 7.02 C ANISOU 992 CG2 VAL C 183 870 932 864 -160 -34 30 C ATOM 993 N ASN C 184 -5.574 -2.423 16.312 1.00 5.96 N ANISOU 993 N ASN C 184 630 740 893 -146 -9 -60 N ATOM 994 CA ASN C 184 -4.998 -1.398 15.450 1.00 6.08 C ANISOU 994 CA ASN C 184 620 713 976 -186 61 -49 C ATOM 995 C ASN C 184 -6.074 -0.642 14.690 1.00 5.93 C ANISOU 995 C ASN C 184 698 668 889 -214 58 -49 C ATOM 996 O ASN C 184 -5.989 0.580 14.548 1.00 6.43 O ANISOU 996 O ASN C 184 768 738 936 -228 -22 -42 O ATOM 997 CB ASN C 184 -3.990 -2.004 14.480 1.00 7.22 C ANISOU 997 CB ASN C 184 745 840 1160 -145 146 2 C ATOM 998 CG ASN C 184 -2.731 -2.500 15.167 1.00 8.14 C ANISOU 998 CG ASN C 184 788 947 1358 -201 166 29 C ATOM 999 OD1 ASN C 184 -2.461 -2.170 16.317 1.00 8.65 O ANISOU 999 OD1 ASN C 184 776 1054 1459 -161 -26 -46 O ATOM 1000 ND2 ASN C 184 -1.941 -3.287 14.443 1.00 9.39 N ANISOU 1000 ND2 ASN C 184 981 1129 1459 -86 325 68 N ATOM 1001 N ARG C 185 -7.085 -1.357 14.202 1.00 5.79 N ANISOU 1001 N ARG C 185 679 665 858 -199 31 -73 N ATOM 1002 CA ARG C 185 -8.176 -0.725 13.478 1.00 5.86 C ANISOU 1002 CA ARG C 185 685 697 843 -173 0 -57 C ATOM 1003 C ARG C 185 -8.991 0.205 14.392 1.00 5.80 C ANISOU 1003 C ARG C 185 715 660 831 -197 -4 -29 C ATOM 1004 O ARG C 185 -9.505 1.236 13.946 1.00 6.39 O ANISOU 1004 O ARG C 185 827 720 883 -143 -13 9 O ATOM 1005 CB ARG C 185 -9.087 -1.802 12.871 1.00 6.40 C ANISOU 1005 CB ARG C 185 802 740 892 -160 -60 -91 C ATOM 1006 CG ARG C 185 -10.189 -1.211 12.009 1.00 7.07 C ANISOU 1006 CG ARG C 185 891 818 979 -211 -164 -71 C ATOM 1007 CD ARG C 185 -11.080 -2.279 11.377 1.00 7.26 C ANISOU 1007 CD ARG C 185 852 851 1054 -182 -160 -120 C ATOM 1008 NE ARG C 185 -11.894 -2.942 12.383 1.00 7.32 N ANISOU 1008 NE ARG C 185 881 790 1112 -158 -191 -147 N ATOM 1009 CZ ARG C 185 -13.027 -3.589 12.125 1.00 7.53 C ANISOU 1009 CZ ARG C 185 888 796 1175 -122 -174 -129 C ATOM 1010 NH1 ARG C 185 -13.690 -4.145 13.126 1.00 7.89 N ANISOU 1010 NH1 ARG C 185 976 791 1231 -210 -87 -63 N ATOM 1011 NH2 ARG C 185 -13.507 -3.654 10.887 1.00 8.38 N ANISOU 1011 NH2 ARG C 185 1003 971 1210 -197 -257 -143 N ATOM 1012 N HIS C 186 -9.145 -0.198 15.651 1.00 5.32 N ANISOU 1012 N HIS C 186 642 605 775 -177 -59 -67 N ATOM 1013 CA HIS C 186 -9.858 0.585 16.656 1.00 5.45 C ANISOU 1013 CA HIS C 186 626 661 785 -168 -9 -99 C ATOM 1014 C HIS C 186 -9.165 1.905 17.011 1.00 5.54 C ANISOU 1014 C HIS C 186 670 620 814 -151 -44 -75 C ATOM 1015 O HIS C 186 -9.839 2.857 17.407 1.00 5.72 O ANISOU 1015 O HIS C 186 707 620 846 -140 -51 -87 O ATOM 1016 CB HIS C 186 -10.025 -0.277 17.913 1.00 5.61 C ANISOU 1016 CB HIS C 186 659 665 806 -128 -48 -118 C ATOM 1017 CG HIS C 186 -10.222 0.507 19.170 1.00 5.46 C ANISOU 1017 CG HIS C 186 615 628 833 -120 -60 -30 C ATOM 1018 ND1 HIS C 186 -11.436 1.030 19.563 1.00 5.89 N ANISOU 1018 ND1 HIS C 186 705 656 875 -140 -58 -57 N ATOM 1019 CD2 HIS C 186 -9.329 0.878 20.116 1.00 5.84 C ANISOU 1019 CD2 HIS C 186 744 630 847 -130 -12 -72 C ATOM 1020 CE1 HIS C 186 -11.271 1.699 20.697 1.00 6.30 C ANISOU 1020 CE1 HIS C 186 822 714 859 -91 -65 -99 C ATOM 1021 NE2 HIS C 186 -10.003 1.616 21.057 1.00 6.43 N ANISOU 1021 NE2 HIS C 186 841 739 863 -77 -3 -72 N ATOM 1022 N LEU C 187 -7.835 1.955 16.911 1.00 5.65 N ANISOU 1022 N LEU C 187 645 644 859 -187 -65 -93 N ATOM 1023 CA LEU C 187 -7.087 3.081 17.479 1.00 5.88 C ANISOU 1023 CA LEU C 187 650 674 912 -184 -148 -61 C ATOM 1024 C LEU C 187 -7.576 4.440 16.998 1.00 5.53 C ANISOU 1024 C LEU C 187 560 670 872 -247 -130 -39 C ATOM 1025 O LEU C 187 -7.518 5.414 17.757 1.00 5.59 O ANISOU 1025 O LEU C 187 594 646 883 -133 -140 -81 O ATOM 1026 CB LEU C 187 -5.603 2.955 17.187 1.00 6.06 C ANISOU 1026 CB LEU C 187 669 644 991 -179 -183 -5 C ATOM 1027 CG LEU C 187 -4.890 1.733 17.745 1.00 6.94 C ANISOU 1027 CG LEU C 187 735 807 1095 -155 -206 1 C ATOM 1028 CD1 LEU C 187 -3.486 1.674 17.193 1.00 7.38 C ANISOU 1028 CD1 LEU C 187 750 847 1207 -147 -172 54 C ATOM 1029 CD2 LEU C 187 -4.911 1.732 19.259 1.00 7.76 C ANISOU 1029 CD2 LEU C 187 848 990 1111 -98 -183 18 C ATOM 1030 N LYS C 188 -8.034 4.521 15.749 1.00 6.16 N ANISOU 1030 N LYS C 188 744 691 904 -198 -139 4 N ATOM 1031 CA LYS C 188 -8.428 5.807 15.181 1.00 6.65 C ANISOU 1031 CA LYS C 188 836 755 937 -257 -204 75 C ATOM 1032 C LYS C 188 -9.574 6.468 15.934 1.00 6.39 C ANISOU 1032 C LYS C 188 717 714 997 -156 -256 48 C ATOM 1033 O LYS C 188 -9.776 7.672 15.776 1.00 7.19 O ANISOU 1033 O LYS C 188 967 725 1039 -66 -315 70 O ATOM 1034 CB LYS C 188 -8.740 5.707 13.688 1.00 7.62 C ANISOU 1034 CB LYS C 188 1034 914 947 -273 -241 70 C ATOM 1035 CG LYS C 188 -9.934 4.839 13.370 1.00 8.38 C ANISOU 1035 CG LYS C 188 1106 1093 983 -288 -291 43 C ATOM 1036 CD LYS C 188 -10.240 4.814 11.878 1.00 9.47 C ANISOU 1036 CD LYS C 188 1287 1263 1049 -303 -275 25 C ATOM 1037 CE LYS C 188 -9.177 4.079 11.068 1.00 10.16 C ANISOU 1037 CE LYS C 188 1419 1372 1070 -394 -193 37 C ATOM 1038 NZ LYS C 188 -9.131 2.610 11.332 1.00 10.16 N ANISOU 1038 NZ LYS C 188 1427 1406 1027 -459 -206 66 N ATOM 1039 N VAL C 189 -10.312 5.728 16.758 1.00 6.41 N ANISOU 1039 N VAL C 189 661 729 1045 -174 -241 -34 N ATOM 1040 CA AVAL C 189 -11.284 6.322 17.677 0.52 6.72 C ANISOU 1040 CA AVAL C 189 654 802 1096 -84 -184 -38 C ATOM 1041 CA BVAL C 189 -11.305 6.405 17.571 0.48 6.85 C ANISOU 1041 CA BVAL C 189 706 782 1114 -170 -169 -10 C ATOM 1042 C VAL C 189 -10.661 7.489 18.452 1.00 6.66 C ANISOU 1042 C VAL C 189 688 747 1094 -33 -155 -41 C ATOM 1043 O VAL C 189 -11.331 8.462 18.804 1.00 7.60 O ANISOU 1043 O VAL C 189 816 857 1215 89 -151 -122 O ATOM 1044 CB AVAL C 189 -11.808 5.267 18.700 0.52 7.05 C ANISOU 1044 CB AVAL C 189 640 915 1124 -24 -141 -50 C ATOM 1045 CB BVAL C 189 -12.142 5.438 18.426 0.48 7.49 C ANISOU 1045 CB BVAL C 189 798 862 1185 -240 -170 26 C ATOM 1046 CG1AVAL C 189 -12.543 5.925 19.863 0.52 7.57 C ANISOU 1046 CG1AVAL C 189 751 973 1151 46 -44 -50 C ATOM 1047 CG1BVAL C 189 -12.743 4.333 17.544 0.48 7.62 C ANISOU 1047 CG1BVAL C 189 841 871 1183 -346 -215 56 C ATOM 1048 CG2AVAL C 189 -12.714 4.259 18.007 0.52 7.52 C ANISOU 1048 CG2AVAL C 189 731 985 1140 21 -130 -11 C ATOM 1049 CG2BVAL C 189 -11.313 4.856 19.553 0.48 7.75 C ANISOU 1049 CG2BVAL C 189 880 840 1226 -248 -163 44 C ATOM 1050 N HIS C 190 -9.370 7.359 18.759 1.00 6.16 N ANISOU 1050 N HIS C 190 631 708 1001 -41 -173 -28 N ATOM 1051 CA HIS C 190 -8.692 8.311 19.632 1.00 6.24 C ANISOU 1051 CA HIS C 190 727 669 973 -109 -106 -37 C ATOM 1052 C HIS C 190 -8.056 9.494 18.917 1.00 6.30 C ANISOU 1052 C HIS C 190 759 661 973 -9 -103 -52 C ATOM 1053 O HIS C 190 -7.448 10.343 19.569 1.00 6.58 O ANISOU 1053 O HIS C 190 890 632 979 -103 -69 -62 O ATOM 1054 CB HIS C 190 -7.668 7.580 20.498 1.00 6.56 C ANISOU 1054 CB HIS C 190 811 743 936 -134 -172 -40 C ATOM 1055 CG HIS C 190 -8.271 6.461 21.288 1.00 6.25 C ANISOU 1055 CG HIS C 190 760 717 898 -108 -197 -84 C ATOM 1056 ND1 HIS C 190 -9.331 6.646 22.151 1.00 6.70 N ANISOU 1056 ND1 HIS C 190 872 723 952 -48 -98 -60 N ATOM 1057 CD2 HIS C 190 -8.016 5.129 21.289 1.00 6.38 C ANISOU 1057 CD2 HIS C 190 867 679 877 -149 -171 -5 C ATOM 1058 CE1 HIS C 190 -9.685 5.478 22.664 1.00 6.68 C ANISOU 1058 CE1 HIS C 190 957 624 957 -77 -95 -60 C ATOM 1059 NE2 HIS C 190 -8.903 4.542 22.160 1.00 6.72 N ANISOU 1059 NE2 HIS C 190 944 711 900 -144 -120 -82 N ATOM 1060 N GLN C 191 -8.207 9.561 17.596 1.00 6.88 N ANISOU 1060 N GLN C 191 875 714 1027 -50 -164 41 N ATOM 1061 CA GLN C 191 -7.840 10.768 16.858 1.00 8.16 C ANISOU 1061 CA GLN C 191 1155 809 1135 -75 -183 76 C ATOM 1062 C GLN C 191 -8.831 11.874 17.144 1.00 9.41 C ANISOU 1062 C GLN C 191 1322 909 1343 82 -182 64 C ATOM 1063 O GLN C 191 -9.992 11.603 17.437 1.00 10.79 O ANISOU 1063 O GLN C 191 1456 1092 1553 238 -137 29 O ATOM 1064 CB GLN C 191 -7.803 10.491 15.360 1.00 8.36 C ANISOU 1064 CB GLN C 191 1202 869 1106 -71 -141 58 C ATOM 1065 CG GLN C 191 -6.648 9.606 14.983 1.00 8.74 C ANISOU 1065 CG GLN C 191 1283 951 1085 -82 -94 71 C ATOM 1066 CD GLN C 191 -6.636 9.237 13.517 1.00 9.47 C ANISOU 1066 CD GLN C 191 1443 1078 1079 -46 -71 100 C ATOM 1067 OE1 GLN C 191 -7.087 10.002 12.661 1.00 11.52 O ANISOU 1067 OE1 GLN C 191 1981 1298 1096 217 -72 141 O ATOM 1068 NE2 GLN C 191 -6.122 8.053 13.216 1.00 8.54 N ANISOU 1068 NE2 GLN C 191 1126 1042 1077 -174 -6 92 N ATOM 1069 N ASN C 192 -8.374 13.117 17.045 1.00 10.27 N ANISOU 1069 N ASN C 192 1582 923 1399 137 -223 39 N ATOM 1070 CA ASN C 192 -9.260 14.258 17.131 1.00 11.99 C ANISOU 1070 CA ASN C 192 1884 1189 1483 252 -249 18 C ATOM 1071 C ASN C 192 -9.962 14.412 15.799 1.00 14.94 C ANISOU 1071 C ASN C 192 2285 1754 1638 279 -310 56 C ATOM 1072 O ASN C 192 -9.322 14.401 14.750 1.00 16.44 O ANISOU 1072 O ASN C 192 2547 2028 1672 277 -317 102 O ATOM 1073 CB ASN C 192 -8.474 15.486 17.580 1.00 11.61 C ANISOU 1073 CB ASN C 192 1853 1141 1418 192 -155 -27 C ATOM 1074 CG ASN C 192 -7.941 15.304 18.988 1.00 11.46 C ANISOU 1074 CG ASN C 192 1745 1259 1349 103 -19 -52 C ATOM 1075 OD1 ASN C 192 -8.714 15.010 19.905 1.00 12.14 O ANISOU 1075 OD1 ASN C 192 1831 1447 1333 82 112 -64 O ATOM 1076 ND2 ASN C 192 -6.628 15.393 19.160 1.00 11.80 N ANISOU 1076 ND2 ASN C 192 1785 1339 1360 122 -37 -36 N ATOM 1077 N LYS C 193 -11.290 14.474 15.853 1.00 16.73 N ANISOU 1077 N LYS C 193 2539 2058 1761 233 -407 44 N ATOM 1078 CA LYS C 193 -12.121 14.423 14.659 1.00 18.50 C ANISOU 1078 CA LYS C 193 2853 2284 1891 193 -380 18 C ATOM 1079 C LYS C 193 -12.080 15.741 13.918 1.00 19.96 C ANISOU 1079 C LYS C 193 3135 2451 1996 164 -357 -17 C ATOM 1080 O LYS C 193 -11.960 16.798 14.534 1.00 20.64 O ANISOU 1080 O LYS C 193 3308 2498 2038 166 -352 -32 O ATOM 1081 CB LYS C 193 -13.564 14.077 15.027 1.00 18.85 C ANISOU 1081 CB LYS C 193 2919 2319 1925 115 -364 23 C ATOM 1082 N PRO C 194 -12.185 15.680 12.585 1.00 20.59 N ANISOU 1082 N PRO C 194 3216 2554 2055 143 -339 -23 N ATOM 1083 CA PRO C 194 -12.153 16.884 11.753 1.00 21.00 C ANISOU 1083 CA PRO C 194 3297 2593 2089 127 -322 -28 C ATOM 1084 C PRO C 194 -13.341 17.796 12.041 1.00 21.18 C ANISOU 1084 C PRO C 194 3337 2606 2104 151 -323 -30 C TER 1085 PRO C 194 HETATM 1086 CA CA B 101 -16.530 -11.753 3.646 1.00 7.03 CA ANISOU 1086 CA CA B 101 826 959 885 18 -229 -31 CA HETATM 1087 C1 MPD C 201 -3.430 1.400 12.261 1.00 20.33 C ANISOU 1087 C1 MPD C 201 2526 2549 2650 -359 -75 -81 C HETATM 1088 C2 MPD C 201 -3.531 0.813 10.859 1.00 20.60 C ANISOU 1088 C2 MPD C 201 2613 2557 2658 -363 -63 -89 C HETATM 1089 O2 MPD C 201 -4.431 1.635 10.066 1.00 20.64 O ANISOU 1089 O2 MPD C 201 2663 2533 2648 -445 -90 -105 O HETATM 1090 CM MPD C 201 -4.130 -0.584 10.979 1.00 20.48 C ANISOU 1090 CM MPD C 201 2616 2513 2654 -367 -65 -93 C HETATM 1091 C3 MPD C 201 -2.129 0.797 10.241 1.00 21.26 C ANISOU 1091 C3 MPD C 201 2726 2667 2685 -269 -43 -78 C HETATM 1092 C4 MPD C 201 -2.046 0.411 8.763 1.00 21.91 C ANISOU 1092 C4 MPD C 201 2852 2762 2712 -177 -36 -53 C HETATM 1093 O4 MPD C 201 -2.241 -1.083 8.511 1.00 22.18 O ANISOU 1093 O4 MPD C 201 2914 2795 2720 -152 -31 -43 O HETATM 1094 C5 MPD C 201 -2.967 1.170 8.003 1.00 22.13 C ANISOU 1094 C5 MPD C 201 2880 2797 2732 -157 -24 -45 C HETATM 1095 C1 MPD C 202 -17.713 -12.882 27.239 1.00 8.91 C ANISOU 1095 C1 MPD C 202 877 1165 1345 -246 303 -140 C HETATM 1096 C2 MPD C 202 -19.084 -13.444 26.938 1.00 10.89 C ANISOU 1096 C2 MPD C 202 1333 1385 1421 -40 244 -12 C HETATM 1097 O2 MPD C 202 -20.114 -12.462 27.268 1.00 13.23 O ANISOU 1097 O2 MPD C 202 1839 1620 1570 95 161 -33 O HETATM 1098 CM MPD C 202 -19.122 -13.737 25.450 1.00 10.52 C ANISOU 1098 CM MPD C 202 1259 1366 1373 3 309 43 C HETATM 1099 C3 MPD C 202 -19.298 -14.759 27.693 1.00 11.48 C ANISOU 1099 C3 MPD C 202 1463 1471 1429 -87 212 79 C HETATM 1100 C4 MPD C 202 -19.342 -14.664 29.216 1.00 11.90 C ANISOU 1100 C4 MPD C 202 1585 1479 1457 -95 192 96 C HETATM 1101 O4 MPD C 202 -19.414 -15.959 29.793 1.00 14.59 O ANISOU 1101 O4 MPD C 202 2087 1831 1626 -105 227 237 O HETATM 1102 C5 MPD C 202 -18.149 -13.893 29.768 1.00 9.26 C ANISOU 1102 C5 MPD C 202 1005 1179 1333 205 216 -55 C HETATM 1103 ZN ZN C 203 -9.013 2.548 22.598 1.00 6.66 ZN ANISOU 1103 ZN ZN C 203 1033 701 798 -116 -96 -82 ZN HETATM 1104 ZN ZN C 204 -21.356 -21.178 17.762 1.00 8.45 ZN ANISOU 1104 ZN ZN C 204 629 962 1619 -219 83 -517 ZN HETATM 1105 C ACT C 205 -10.725 9.443 23.887 1.00 14.89 C ANISOU 1105 C ACT C 205 1973 1458 2228 121 272 -145 C HETATM 1106 O ACT C 205 -10.675 8.615 24.829 1.00 15.62 O ANISOU 1106 O ACT C 205 2078 1593 2264 73 195 -84 O HETATM 1107 OXT ACT C 205 -10.602 9.015 22.710 1.00 13.82 O ANISOU 1107 OXT ACT C 205 1759 1290 2204 291 403 -248 O HETATM 1108 CH3 ACT C 205 -10.916 10.899 24.166 1.00 15.21 C ANISOU 1108 CH3 ACT C 205 2047 1490 2240 131 239 -167 C HETATM 1109 O HOH A 101 -17.792 -9.795 4.366 1.00 7.89 O ANISOU 1109 O HOH A 101 926 1105 965 61 -227 -81 O HETATM 1110 O HOH A 102 -8.668 -16.919 16.452 1.00 8.01 O ANISOU 1110 O HOH A 102 910 1007 1126 -40 48 -105 O HETATM 1111 O HOH A 103 -14.964 -9.954 3.390 1.00 8.23 O ANISOU 1111 O HOH A 103 934 1196 997 -107 -55 -67 O HETATM 1112 O HOH A 104 -12.155 -3.301 8.359 1.00 11.26 O ANISOU 1112 O HOH A 104 1623 1390 1263 -169 -394 -188 O HETATM 1113 O HOH A 105 -20.382 -10.664 4.702 1.00 13.25 O ANISOU 1113 O HOH A 105 1118 2409 1506 -18 -292 -426 O HETATM 1114 O HOH A 106 -7.427 -1.890 9.560 1.00 12.72 O ANISOU 1114 O HOH A 106 1631 1833 1369 -142 154 227 O HETATM 1115 O HOH A 107 -13.958 -1.995 6.691 1.00 13.38 O ANISOU 1115 O HOH A 107 1566 1754 1764 -511 -177 352 O HETATM 1116 O HOH A 108 -4.958 -5.246 9.362 1.00 15.83 O ANISOU 1116 O HOH A 108 1741 2142 2131 -529 458 -673 O HETATM 1117 O HOH A 109 -21.073 -8.973 6.745 1.00 12.32 O ANISOU 1117 O HOH A 109 1331 1755 1595 -114 -202 -203 O HETATM 1118 O HOH A 110 -9.812 -1.842 8.144 1.00 15.81 O ANISOU 1118 O HOH A 110 2109 2156 1741 -769 -268 208 O HETATM 1119 O HOH A 111 -8.746 -20.908 20.532 1.00 14.65 O ANISOU 1119 O HOH A 111 1853 1278 2436 184 623 278 O HETATM 1120 O HOH A 112 -1.799 -11.156 5.828 1.00 18.65 O ANISOU 1120 O HOH A 112 1708 2439 2937 -855 1267 -993 O HETATM 1121 O HOH A 113 -5.968 -25.341 9.163 1.00 16.30 O ANISOU 1121 O HOH A 113 2114 2097 1982 423 -65 -125 O HETATM 1122 O HOH A 114 -20.151 1.038 6.052 1.00 21.62 O ANISOU 1122 O HOH A 114 3332 2820 2063 -241 92 289 O HETATM 1123 O HOH A 115 -1.813 -28.506 15.672 1.00 19.97 O ANISOU 1123 O HOH A 115 2595 2658 2334 321 -3 655 O HETATM 1124 O HOH A 116 -6.283 -10.032 2.431 1.00 22.46 O ANISOU 1124 O HOH A 116 3752 2620 2162 -825 1054 -3 O HETATM 1125 O HOH A 117 -22.856 -5.961 10.174 1.00 20.97 O ANISOU 1125 O HOH A 117 1570 3067 3331 -204 -145 -728 O HETATM 1126 O HOH A 118 -8.121 -26.980 8.869 1.00 20.43 O ANISOU 1126 O HOH A 118 2861 1946 2955 639 -4 -770 O HETATM 1127 O AHOH A 119 -3.720 -16.835 20.365 0.54 12.60 O ANISOU 1127 O AHOH A 119 1169 1801 1818 -13 -168 419 O HETATM 1128 O BHOH A 119 -3.532 -18.103 20.860 0.46 15.75 O ANISOU 1128 O BHOH A 119 1491 2645 1848 -90 -358 258 O HETATM 1129 O AHOH A 120 -15.974 -10.772 -0.496 0.46 15.63 O ANISOU 1129 O AHOH A 120 1970 2480 1491 31 -71 419 O HETATM 1130 O BHOH A 120 -15.427 -10.226 -0.335 0.54 14.70 O ANISOU 1130 O BHOH A 120 2070 1720 1795 195 553 850 O HETATM 1131 O HOH A 121 -14.444 -1.682 3.708 1.00 24.66 O ANISOU 1131 O HOH A 121 3914 2737 2720 -283 615 816 O HETATM 1132 O HOH A 122 -9.917 -31.298 9.843 1.00 26.28 O ANISOU 1132 O HOH A 122 3308 2978 3698 539 -81 -310 O HETATM 1133 O HOH A 123 -0.841 -21.360 15.094 1.00 20.11 O ANISOU 1133 O HOH A 123 2179 2735 2727 -11 -49 -406 O HETATM 1134 O HOH A 124 1.236 -13.954 6.601 1.00 22.58 O ANISOU 1134 O HOH A 124 3173 2352 3055 161 703 -387 O HETATM 1135 O HOH A 125 -10.409 -2.981 5.676 1.00 21.71 O ANISOU 1135 O HOH A 125 2923 2670 2655 -1325 -88 104 O HETATM 1136 O HOH A 126 -8.789 -9.284 1.031 1.00 24.75 O ANISOU 1136 O HOH A 126 3133 3453 2818 -30 1242 175 O HETATM 1137 O HOH A 127 -21.713 1.728 4.380 1.00 19.91 O ANISOU 1137 O HOH A 127 2547 3132 1888 180 285 160 O HETATM 1138 O HOH A 128 -6.732 -22.653 8.584 1.00 21.94 O ANISOU 1138 O HOH A 128 2774 2059 3504 -596 -717 756 O HETATM 1139 O HOH A 129 -23.109 -8.252 8.669 1.00 20.72 O ANISOU 1139 O HOH A 129 2843 2539 2491 -95 26 -285 O HETATM 1140 O HOH A 130 -9.286 -27.698 11.508 1.00 29.22 O ANISOU 1140 O HOH A 130 4136 3510 3455 -299 -76 281 O HETATM 1141 O HOH A 131 -26.865 -1.696 6.232 1.00 27.55 O ANISOU 1141 O HOH A 131 3002 3778 3688 83 -1277 -109 O HETATM 1142 O HOH A 132 -12.810 -28.380 13.815 1.00 22.88 O ANISOU 1142 O HOH A 132 3130 1675 3887 -58 -267 199 O HETATM 1143 O HOH A 133 -22.846 -0.281 5.330 1.00 23.99 O ANISOU 1143 O HOH A 133 3216 3407 2493 631 -543 133 O HETATM 1144 O HOH A 134 1.732 -7.231 11.786 1.00 24.58 O ANISOU 1144 O HOH A 134 3017 3135 3187 -564 19 395 O HETATM 1145 O HOH A 135 -0.313 -16.089 13.046 1.00 25.86 O ANISOU 1145 O HOH A 135 2587 3159 4080 885 767 -810 O HETATM 1146 O HOH A 136 0.509 -10.942 7.503 1.00 28.22 O ANISOU 1146 O HOH A 136 3255 3859 3609 42 207 -621 O HETATM 1147 O HOH A 137 -11.136 -26.343 13.562 1.00 26.26 O ANISOU 1147 O HOH A 137 3111 3067 3798 568 155 -719 O HETATM 1148 O HOH A 138 -5.511 -2.972 7.742 1.00 22.84 O ANISOU 1148 O HOH A 138 2730 3100 2850 377 1195 -3 O HETATM 1149 O HOH A 139 -21.594 -2.978 16.471 1.00 23.30 O ANISOU 1149 O HOH A 139 3389 2219 3246 221 1449 405 O HETATM 1150 O AHOH A 140 -11.635 -9.437 2.328 0.54 12.53 O ANISOU 1150 O AHOH A 140 1770 1624 1369 -131 -311 202 O HETATM 1151 O BHOH A 140 -10.948 -8.459 2.389 0.46 14.56 O ANISOU 1151 O BHOH A 140 1546 1601 2384 -79 224 471 O HETATM 1152 O HOH A 141 -0.212 -26.244 15.484 1.00 16.43 O ANISOU 1152 O HOH A 141 1497 2584 2162 603 -131 365 O HETATM 1153 O HOH A 142 -0.961 -13.155 9.284 1.00 22.90 O ANISOU 1153 O HOH A 142 2077 2570 4054 -585 723 -532 O HETATM 1154 O HOH A 143 -2.406 -5.478 12.236 1.00 24.59 O ANISOU 1154 O HOH A 143 2619 3624 3099 -814 588 157 O HETATM 1155 O HOH A 144 -0.538 -10.491 19.021 1.00 23.19 O ANISOU 1155 O HOH A 144 2264 3255 3293 149 -252 -59 O HETATM 1156 O HOH A 145 -0.531 -12.808 20.361 1.00 25.03 O ANISOU 1156 O HOH A 145 2856 3753 2902 -197 127 -16 O HETATM 1157 O HOH A 146 -5.128 -3.708 -0.838 1.00 32.51 O ANISOU 1157 O HOH A 146 3939 4405 4009 -58 312 230 O HETATM 1158 O HOH A 147 0.610 -19.021 14.631 1.00 27.13 O ANISOU 1158 O HOH A 147 3427 3080 3803 13 4 74 O HETATM 1159 O HOH A 148 -7.246 -2.984 5.368 1.00 30.06 O ANISOU 1159 O HOH A 148 4201 3731 3490 -341 -75 66 O HETATM 1160 O HOH A 149 -0.350 -3.538 5.949 1.00 24.86 O ANISOU 1160 O HOH A 149 3705 2936 2806 -739 -76 633 O HETATM 1161 O HOH A 150 -19.037 -1.660 3.599 1.00 29.55 O ANISOU 1161 O HOH A 150 3672 4048 3506 181 56 465 O HETATM 1162 O HOH A 151 -17.636 -3.043 1.734 1.00 27.03 O ANISOU 1162 O HOH A 151 3993 3122 3153 681 364 673 O HETATM 1163 O HOH A 152 -23.191 3.229 5.935 1.00 29.32 O ANISOU 1163 O HOH A 152 3792 4023 3326 -97 -402 107 O HETATM 1164 O HOH A 153 -25.927 3.258 4.960 1.00 31.88 O ANISOU 1164 O HOH A 153 3906 4310 3897 58 -94 30 O HETATM 1165 O HOH A 154 -10.629 -1.242 3.815 1.00 27.43 O ANISOU 1165 O HOH A 154 3789 3169 3463 -104 -67 644 O HETATM 1166 O HOH A 155 -23.534 -3.949 12.692 1.00 29.18 O ANISOU 1166 O HOH A 155 3711 3460 3916 -495 -120 364 O HETATM 1167 O AHOH A 156 1.325 -13.392 9.086 0.68 14.93 O ANISOU 1167 O AHOH A 156 924 2298 2450 -226 385 -1111 O HETATM 1168 O BHOH A 156 1.065 -14.539 10.827 0.32 10.96 O ANISOU 1168 O BHOH A 156 440 2107 1619 346 101 -746 O HETATM 1169 O HOH A 157 -0.345 -6.738 13.565 1.00 19.71 O ANISOU 1169 O HOH A 157 2889 2217 2382 -894 -79 199 O HETATM 1170 O AHOH A 158 0.675 -10.044 16.219 0.59 23.30 O ANISOU 1170 O AHOH A 158 2187 3573 3092 57 -658 411 O HETATM 1171 O BHOH A 158 -0.446 -10.894 16.777 0.41 24.56 O ANISOU 1171 O BHOH A 158 2591 3526 3215 155 -520 265 O HETATM 1172 O HOH A 159 -23.334 -1.931 15.145 1.00 30.01 O ANISOU 1172 O HOH A 159 3988 3667 3749 -120 356 756 O HETATM 1173 O HOH A 160 -5.112 -22.754 20.871 1.00 28.93 O ANISOU 1173 O HOH A 160 4192 3837 2962 731 -316 319 O HETATM 1174 O HOH A 161 -25.510 -9.349 7.492 1.00 30.62 O ANISOU 1174 O HOH A 161 3751 4117 3765 -865 -126 -136 O HETATM 1175 O HOH A 162 3.549 -14.188 9.828 1.00 28.80 O ANISOU 1175 O HOH A 162 3345 3720 3878 -3 -392 -277 O HETATM 1176 O HOH A 163 -22.807 -2.862 2.770 1.00 28.48 O ANISOU 1176 O HOH A 163 3926 3799 3098 223 -334 569 O HETATM 1177 O HOH A 164 -22.810 -4.691 14.843 1.00 26.13 O ANISOU 1177 O HOH A 164 3236 3191 3502 -324 148 1107 O HETATM 1178 O AHOH A 165 -8.731 -29.591 7.362 0.66 24.58 O ANISOU 1178 O AHOH A 165 2938 2856 3545 1101 399 -545 O HETATM 1179 O BHOH A 166 -8.035 -28.568 6.469 0.60 25.55 O ANISOU 1179 O BHOH A 166 3337 3226 3143 105 108 -597 O HETATM 1180 O AHOH A 167 -14.089 -9.378 0.993 0.41 25.09 O ANISOU 1180 O AHOH A 167 3189 3123 3221 20 150 311 O HETATM 1181 O BHOH A 167 -12.847 -10.105 1.723 0.59 22.49 O ANISOU 1181 O BHOH A 167 2898 2536 3110 153 1031 -1 O HETATM 1182 O HOH A 168 -2.673 -3.049 11.562 1.00 27.41 O ANISOU 1182 O HOH A 168 3729 3608 3076 -25 335 -286 O HETATM 1183 O AHOH A 169 -1.327 -18.095 19.958 0.36 22.17 O ANISOU 1183 O AHOH A 169 2149 2548 3727 -74 375 -615 O HETATM 1184 O BHOH A 169 -6.457 -15.228 16.331 0.64 12.53 O ANISOU 1184 O BHOH A 169 723 935 3102 157 362 -858 O HETATM 1185 O HOH A 170 -17.491 0.585 5.663 1.00 29.50 O ANISOU 1185 O HOH A 170 3661 3978 3571 -247 207 473 O HETATM 1186 O AHOH A 171 -24.707 -10.106 -0.695 0.62 24.46 O ANISOU 1186 O AHOH A 171 3287 3084 2923 222 20 -772 O HETATM 1187 O BHOH A 171 -22.991 -9.597 0.336 0.38 25.84 O ANISOU 1187 O BHOH A 171 3289 3336 3192 206 -174 -262 O HETATM 1188 O HOH A 172 -0.765 -24.457 17.517 1.00 29.58 O ANISOU 1188 O HOH A 172 3675 3804 3761 160 -68 -262 O HETATM 1189 O HOH A 173 -19.750 1.236 2.857 1.00 29.87 O ANISOU 1189 O HOH A 173 3850 3749 3750 197 -58 73 O HETATM 1190 O HOH A 174 -4.849 -12.658 19.401 1.00 9.09 O ANISOU 1190 O HOH A 174 1125 1055 1273 150 102 35 O HETATM 1191 O HOH B 201 -15.753 -15.891 12.426 1.00 6.96 O ANISOU 1191 O HOH B 201 839 827 979 -63 71 -127 O HETATM 1192 O HOH B 202 -13.064 -0.497 15.492 1.00 7.44 O ANISOU 1192 O HOH B 202 794 821 1211 -93 -78 -41 O HETATM 1193 O HOH B 203 -17.293 -12.050 5.962 1.00 7.90 O ANISOU 1193 O HOH B 203 955 1097 952 92 -117 32 O HETATM 1194 O HOH B 204 -17.544 -11.014 1.564 1.00 8.46 O ANISOU 1194 O HOH B 204 1139 1091 984 -45 -349 -2 O HETATM 1195 O HOH B 205 -11.695 -15.872 9.795 1.00 9.95 O ANISOU 1195 O HOH B 205 1740 1052 988 220 403 47 O HETATM 1196 O HOH B 206 -14.825 -12.943 4.862 1.00 8.09 O ANISOU 1196 O HOH B 206 1003 1144 928 147 -225 -131 O HETATM 1197 O HOH B 207 -18.899 -10.590 7.706 1.00 10.51 O ANISOU 1197 O HOH B 207 920 1825 1249 -52 -217 -461 O HETATM 1198 O HOH B 208 -17.962 -13.602 3.297 1.00 8.75 O ANISOU 1198 O HOH B 208 1034 1265 1026 -190 -335 83 O HETATM 1199 O HOH B 209 -15.057 -12.751 1.991 1.00 8.58 O ANISOU 1199 O HOH B 209 1007 1297 954 103 -209 -64 O HETATM 1200 O HOH B 210 -19.720 -15.580 14.653 1.00 10.38 O ANISOU 1200 O HOH B 210 1464 1314 1168 26 297 -234 O HETATM 1201 O HOH B 211 -17.741 -14.427 16.119 1.00 10.31 O ANISOU 1201 O HOH B 211 1454 1266 1196 196 -205 -152 O HETATM 1202 O HOH B 212 -1.505 -19.207 -2.303 1.00 13.84 O ANISOU 1202 O HOH B 212 1620 2079 1560 59 623 -439 O HETATM 1203 O HOH B 213 -13.515 -19.071 7.689 1.00 12.22 O ANISOU 1203 O HOH B 213 1200 2532 912 597 81 -109 O HETATM 1204 O HOH B 214 4.033 -15.861 0.029 1.00 12.35 O ANISOU 1204 O HOH B 214 1525 1874 1294 -148 427 -279 O HETATM 1205 O HOH B 215 -12.247 -12.550 2.069 1.00 14.84 O ANISOU 1205 O HOH B 215 1160 2876 1604 -426 -439 856 O HETATM 1206 O HOH B 216 0.504 -20.101 1.819 1.00 14.76 O ANISOU 1206 O HOH B 216 2256 1808 1543 555 1038 374 O HETATM 1207 O HOH B 217 -19.328 -15.451 4.808 1.00 12.04 O ANISOU 1207 O HOH B 217 1373 1688 1514 -359 -285 261 O HETATM 1208 O HOH B 218 -22.071 -14.321 14.810 1.00 14.62 O ANISOU 1208 O HOH B 218 1887 1521 2148 -350 154 -72 O HETATM 1209 O AHOH B 219 -22.641 -13.275 7.684 0.52 7.67 O ANISOU 1209 O AHOH B 219 485 1273 1158 -227 -192 219 O HETATM 1210 O BHOH B 219 -21.684 -15.294 6.839 0.48 18.07 O ANISOU 1210 O BHOH B 219 1823 2463 2579 181 -320 -425 O HETATM 1211 O HOH B 220 4.341 -20.321 4.722 1.00 14.98 O ANISOU 1211 O HOH B 220 1419 2774 1499 142 75 200 O HETATM 1212 O HOH B 221 -14.327 2.755 21.337 1.00 15.49 O ANISOU 1212 O HOH B 221 1674 2077 2134 88 107 -836 O HETATM 1213 O HOH B 222 -6.860 -20.765 4.397 1.00 15.16 O ANISOU 1213 O HOH B 222 2036 2198 1525 -34 366 -211 O HETATM 1214 O HOH B 223 -21.437 -8.403 12.363 1.00 18.36 O ANISOU 1214 O HOH B 223 961 3357 2657 -458 89 522 O HETATM 1215 O HOH B 224 -13.753 4.004 13.601 1.00 17.42 O ANISOU 1215 O HOH B 224 1220 1549 3850 41 -619 870 O HETATM 1216 O HOH B 225 -15.609 -16.837 -1.277 1.00 16.74 O ANISOU 1216 O HOH B 225 2191 2216 1952 472 -292 -373 O HETATM 1217 O HOH B 226 -5.747 -12.777 1.670 1.00 20.70 O ANISOU 1217 O HOH B 226 3784 2561 1522 -214 774 400 O HETATM 1218 O HOH B 227 5.445 -17.659 1.452 1.00 16.74 O ANISOU 1218 O HOH B 227 2295 2412 1653 94 578 140 O HETATM 1219 O HOH B 228 -3.056 -21.787 3.652 1.00 19.43 O ANISOU 1219 O HOH B 228 2237 2922 2223 -432 985 -781 O HETATM 1220 O HOH B 229 0.835 -15.792 8.900 1.00 22.23 O ANISOU 1220 O HOH B 229 1989 3037 3421 -228 248 -432 O HETATM 1221 O HOH B 230 -20.161 -0.307 16.367 1.00 17.55 O ANISOU 1221 O HOH B 230 1379 3133 2155 329 147 744 O HETATM 1222 O HOH B 231 -18.732 -9.134 20.639 1.00 18.32 O ANISOU 1222 O HOH B 231 2980 1551 2430 -252 374 -113 O HETATM 1223 O HOH B 232 -1.306 -13.764 4.924 1.00 20.90 O ANISOU 1223 O HOH B 232 2433 2171 3336 321 1321 -395 O HETATM 1224 O HOH B 233 -5.513 -22.587 3.302 1.00 21.52 O ANISOU 1224 O HOH B 233 1958 3126 3092 531 -110 -1716 O HETATM 1225 O HOH B 234 -14.516 0.289 8.266 1.00 18.39 O ANISOU 1225 O HOH B 234 3056 2310 1623 -387 351 213 O HETATM 1226 O HOH B 235 -21.474 -8.802 19.965 1.00 20.94 O ANISOU 1226 O HOH B 235 2459 2427 3071 38 596 669 O HETATM 1227 O HOH B 236 -18.039 -6.675 21.705 1.00 18.86 O ANISOU 1227 O HOH B 236 3051 1962 2154 -433 308 14 O HETATM 1228 O HOH B 237 -11.993 -13.162 -0.695 1.00 22.50 O ANISOU 1228 O HOH B 237 2629 3362 2558 708 -380 336 O HETATM 1229 O HOH B 238 -8.084 -21.143 0.088 1.00 26.27 O ANISOU 1229 O HOH B 238 3505 3514 2963 543 714 -575 O HETATM 1230 O HOH B 239 -1.714 -24.384 5.032 1.00 25.91 O ANISOU 1230 O HOH B 239 3924 2943 2980 -612 -283 -402 O HETATM 1231 O HOH B 240 -2.940 -17.285 -3.645 1.00 22.76 O ANISOU 1231 O HOH B 240 2872 3777 1998 1083 508 120 O HETATM 1232 O HOH B 241 -8.973 -12.577 1.138 1.00 24.29 O ANISOU 1232 O HOH B 241 3075 3513 2641 332 37 -1110 O HETATM 1233 O HOH B 242 3.681 -17.282 12.276 1.00 21.37 O ANISOU 1233 O HOH B 242 3223 2709 2190 -153 -36 201 O HETATM 1234 O HOH B 243 -16.065 3.076 7.869 1.00 25.17 O ANISOU 1234 O HOH B 243 3365 3411 2788 157 1139 552 O HETATM 1235 O HOH B 244 -4.766 -22.803 5.783 1.00 22.46 O ANISOU 1235 O HOH B 244 3022 3063 2451 -607 445 -610 O HETATM 1236 O HOH B 245 1.010 -17.656 11.567 1.00 22.56 O ANISOU 1236 O HOH B 245 2864 2773 2935 725 -407 -884 O HETATM 1237 O HOH B 246 -21.647 -9.910 10.224 1.00 29.66 O ANISOU 1237 O HOH B 246 3653 3711 3905 -242 -434 185 O HETATM 1238 O HOH B 247 -21.035 -11.951 8.878 1.00 22.84 O ANISOU 1238 O HOH B 247 2824 3172 2683 -321 588 262 O HETATM 1239 O HOH B 248 -23.351 -11.453 6.138 1.00 25.23 O ANISOU 1239 O HOH B 248 3219 3404 2961 104 -707 -226 O HETATM 1240 O HOH B 249 -15.779 5.224 20.620 1.00 29.77 O ANISOU 1240 O HOH B 249 3456 3876 3979 303 -438 -173 O HETATM 1241 O HOH B 250 4.880 -22.444 6.399 1.00 26.16 O ANISOU 1241 O HOH B 250 3406 3141 3392 14 303 888 O HETATM 1242 O HOH B 251 -20.317 -4.510 14.632 1.00 17.99 O ANISOU 1242 O HOH B 251 2127 1844 2864 408 767 952 O HETATM 1243 O AHOH B 252 -11.462 -20.709 2.937 0.57 12.61 O ANISOU 1243 O AHOH B 252 1933 1573 1286 276 95 -470 O HETATM 1244 O BHOH B 252 -11.001 -20.114 3.143 0.43 14.95 O ANISOU 1244 O BHOH B 252 2444 1762 1474 745 236 -398 O HETATM 1245 O HOH B 253 -20.661 -13.156 6.049 1.00 18.69 O ANISOU 1245 O HOH B 253 2051 2466 2583 -394 -571 468 O HETATM 1246 O AHOH B 254 1.178 -13.230 -1.334 0.46 19.78 O ANISOU 1246 O AHOH B 254 2569 2107 2840 682 276 57 O HETATM 1247 O BHOH B 254 0.193 -13.717 -1.864 0.54 18.71 O ANISOU 1247 O BHOH B 254 2641 2063 2404 351 483 312 O HETATM 1248 O HOH B 255 -8.677 -20.221 2.517 1.00 24.25 O ANISOU 1248 O HOH B 255 3053 3778 2383 -62 738 -267 O HETATM 1249 O HOH B 256 -0.050 -26.491 4.988 1.00 27.20 O ANISOU 1249 O HOH B 256 3673 3463 3198 300 288 204 O HETATM 1250 O HOH B 257 -21.765 -15.815 3.556 1.00 29.76 O ANISOU 1250 O HOH B 257 3608 3696 4004 -269 -770 -71 O HETATM 1251 O HOH B 258 -5.834 -20.852 -3.078 1.00 27.84 O ANISOU 1251 O HOH B 258 3568 3637 3374 577 780 -1099 O HETATM 1252 O HOH B 259 4.090 -24.420 4.149 1.00 26.61 O ANISOU 1252 O HOH B 259 3388 3483 3241 533 38 398 O HETATM 1253 O HOH B 260 -1.860 -13.046 2.223 1.00 29.91 O ANISOU 1253 O HOH B 260 4283 3520 3560 72 437 -153 O HETATM 1254 O HOH B 261 7.383 -19.959 10.967 1.00 29.28 O ANISOU 1254 O HOH B 261 3463 3923 3738 285 -527 350 O HETATM 1255 O HOH B 262 -13.343 2.701 23.977 1.00 26.77 O ANISOU 1255 O HOH B 262 3160 3504 3508 263 -230 -986 O HETATM 1256 O HOH B 263 -22.701 -14.230 9.990 1.00 26.54 O ANISOU 1256 O HOH B 263 2643 3740 3703 605 -870 550 O HETATM 1257 O HOH B 264 -6.420 -23.248 -1.549 1.00 28.38 O ANISOU 1257 O HOH B 264 3012 3746 4027 245 132 -490 O HETATM 1258 O HOH B 265 -22.940 -10.366 21.707 1.00 20.74 O ANISOU 1258 O HOH B 265 2473 2070 3335 236 922 -115 O HETATM 1259 O AHOH B 266 -13.864 9.646 17.425 0.55 15.62 O ANISOU 1259 O AHOH B 266 1699 1556 2681 -194 -141 165 O HETATM 1260 O BHOH B 266 -14.120 9.357 19.002 0.45 17.26 O ANISOU 1260 O BHOH B 266 1948 1833 2776 -37 -187 -369 O HETATM 1261 O HOH B 267 7.631 -14.322 3.268 1.00 24.54 O ANISOU 1261 O HOH B 267 2704 3929 2690 -680 461 957 O HETATM 1262 O HOH B 268 8.120 -18.832 4.040 1.00 32.06 O ANISOU 1262 O HOH B 268 4060 4149 3974 6 -143 150 O HETATM 1263 O AHOH B 269 -13.928 -6.868 16.705 0.59 14.91 O ANISOU 1263 O AHOH B 269 2334 2078 1253 -1262 36 -109 O HETATM 1264 O BHOH B 269 -14.767 -8.732 17.319 0.41 12.09 O ANISOU 1264 O BHOH B 269 1824 1056 1715 -242 -417 74 O HETATM 1265 O HOH B 270 -13.881 7.884 11.812 1.00 26.38 O ANISOU 1265 O HOH B 270 3063 2880 4078 -111 -101 829 O HETATM 1266 O HOH B 271 -6.174 -14.047 -3.268 1.00 29.35 O ANISOU 1266 O HOH B 271 3738 3550 3865 355 -368 582 O HETATM 1267 O HOH B 272 -16.930 -17.684 -3.413 1.00 26.90 O ANISOU 1267 O HOH B 272 3416 3453 3351 72 -769 11 O HETATM 1268 O HOH B 273 -20.306 -3.654 19.375 1.00 27.40 O ANISOU 1268 O HOH B 273 3661 3080 3668 465 1115 116 O HETATM 1269 O AHOH B 274 -22.926 -10.291 17.530 0.56 18.86 O ANISOU 1269 O AHOH B 274 1470 2238 3459 516 851 -157 O HETATM 1270 O BHOH B 274 -23.212 -10.702 15.442 0.44 23.97 O ANISOU 1270 O BHOH B 274 2700 3068 3339 -46 -146 21 O HETATM 1271 O AHOH B 275 3.540 -24.821 6.461 0.53 21.80 O ANISOU 1271 O AHOH B 275 2693 3054 2536 247 711 482 O HETATM 1272 O BHOH B 275 2.236 -25.683 5.699 0.47 22.24 O ANISOU 1272 O BHOH B 275 3195 2929 2326 109 826 -179 O HETATM 1273 O HOH B 276 -21.308 -17.091 8.353 1.00 22.63 O ANISOU 1273 O HOH B 276 3512 2454 2633 -742 -121 -298 O HETATM 1274 O HOH B 277 -17.113 -10.720 18.969 1.00 12.74 O ANISOU 1274 O HOH B 277 1620 1122 2097 -85 -489 39 O HETATM 1275 O HOH B 278 -1.244 -22.258 1.655 1.00 18.57 O ANISOU 1275 O HOH B 278 1859 3607 1588 124 349 -378 O HETATM 1276 O HOH B 279 0.157 -24.435 2.426 1.00 20.88 O ANISOU 1276 O HOH B 279 2686 3131 2118 -1144 449 -76 O HETATM 1277 O HOH B 280 3.053 -21.193 2.392 1.00 14.22 O ANISOU 1277 O HOH B 280 2073 2055 1276 54 251 127 O HETATM 1278 O HOH B 281 -22.646 -7.408 14.794 1.00 29.59 O ANISOU 1278 O HOH B 281 3656 3890 3695 73 36 -230 O HETATM 1279 O HOH C 301 -12.771 -14.017 17.877 1.00 6.39 O ANISOU 1279 O HOH C 301 672 806 952 -148 103 -160 O HETATM 1280 O HOH C 302 -10.112 -14.753 17.610 1.00 7.29 O ANISOU 1280 O HOH C 302 907 892 971 5 -20 -105 O HETATM 1281 O HOH C 303 -7.010 2.900 13.372 1.00 7.51 O ANISOU 1281 O HOH C 303 1049 787 1018 -227 -20 17 O HETATM 1282 O HOH C 304 -3.099 -10.816 17.973 1.00 8.80 O ANISOU 1282 O HOH C 304 978 1043 1323 130 -6 -38 O HETATM 1283 O HOH C 305 -11.523 -2.835 15.348 1.00 7.38 O ANISOU 1283 O HOH C 305 835 941 1029 -95 -112 -173 O HETATM 1284 O HOH C 306 -13.032 -12.999 20.454 1.00 8.36 O ANISOU 1284 O HOH C 306 997 1273 906 156 -102 -69 O HETATM 1285 O HOH C 307 -15.079 -18.358 28.546 1.00 8.03 O ANISOU 1285 O HOH C 307 1008 940 1104 214 163 130 O HETATM 1286 O HOH C 308 -15.292 -11.492 20.726 1.00 9.35 O ANISOU 1286 O HOH C 308 1008 1008 1537 -32 -194 12 O HETATM 1287 O HOH C 309 -14.088 -12.514 15.871 1.00 8.22 O ANISOU 1287 O HOH C 309 785 1163 1174 -111 20 -139 O HETATM 1288 O HOH C 310 -12.252 1.787 14.075 1.00 9.69 O ANISOU 1288 O HOH C 310 914 1044 1723 -3 -23 194 O HETATM 1289 O HOH C 311 -16.848 -12.232 22.834 1.00 11.35 O ANISOU 1289 O HOH C 311 1512 1060 1739 38 343 -170 O HETATM 1290 O HOH C 312 -8.777 12.428 20.991 1.00 12.19 O ANISOU 1290 O HOH C 312 1765 1474 1394 457 166 -161 O HETATM 1291 O HOH C 313 -25.492 -26.178 11.369 1.00 11.30 O ANISOU 1291 O HOH C 313 1474 1688 1132 -810 -139 123 O HETATM 1292 O HOH C 314 -15.811 -13.780 14.280 1.00 12.00 O ANISOU 1292 O HOH C 314 934 1746 1879 131 -238 -830 O HETATM 1293 O HOH C 315 -24.130 -21.946 9.298 1.00 12.62 O ANISOU 1293 O HOH C 315 1199 1924 1672 -173 -149 18 O HETATM 1294 O HOH C 316 -20.511 -31.508 17.822 1.00 14.16 O ANISOU 1294 O HOH C 316 1519 2062 1799 -754 -536 184 O HETATM 1295 O HOH C 317 -3.046 -12.676 21.527 1.00 12.98 O ANISOU 1295 O HOH C 317 1230 1937 1764 65 58 0 O HETATM 1296 O HOH C 318 -7.571 -20.643 6.965 1.00 13.36 O ANISOU 1296 O HOH C 318 1186 2185 1706 44 76 -336 O HETATM 1297 O HOH C 319 -6.227 6.675 10.570 1.00 13.66 O ANISOU 1297 O HOH C 319 2398 1384 1409 -450 109 -44 O HETATM 1298 O HOH C 320 -15.449 -28.532 12.866 1.00 17.33 O ANISOU 1298 O HOH C 320 2469 1376 2739 505 -146 -290 O HETATM 1299 O HOH C 321 -10.414 -12.364 27.237 1.00 15.05 O ANISOU 1299 O HOH C 321 2660 1973 1087 -965 -364 73 O HETATM 1300 O HOH C 322 -13.325 -4.409 26.601 1.00 18.23 O ANISOU 1300 O HOH C 322 2694 1986 2247 -720 1070 -179 O HETATM 1301 O HOH C 323 -3.498 -15.292 22.794 1.00 17.37 O ANISOU 1301 O HOH C 323 1472 2824 2305 508 188 840 O HETATM 1302 O HOH C 324 -8.876 -24.780 7.252 1.00 17.78 O ANISOU 1302 O HOH C 324 2206 1520 3028 566 822 -136 O HETATM 1303 O HOH C 325 0.672 -4.526 14.994 1.00 18.72 O ANISOU 1303 O HOH C 325 1408 2375 3328 244 649 484 O HETATM 1304 O HOH C 326 -5.906 13.447 15.604 1.00 16.06 O ANISOU 1304 O HOH C 326 2406 1561 2137 -49 431 391 O HETATM 1305 O HOH C 327 -21.835 -30.675 20.079 1.00 18.02 O ANISOU 1305 O HOH C 327 1424 3179 2244 -520 -143 733 O HETATM 1306 O HOH C 328 -7.265 0.874 9.920 1.00 19.51 O ANISOU 1306 O HOH C 328 2333 2197 2883 -938 786 -1257 O HETATM 1307 O HOH C 329 -21.901 -27.378 6.040 1.00 22.90 O ANISOU 1307 O HOH C 329 2914 2945 2841 -592 77 -341 O HETATM 1308 O HOH C 330 -15.850 -26.453 16.960 1.00 19.02 O ANISOU 1308 O HOH C 330 2588 2085 2554 -308 -281 475 O HETATM 1309 O HOH C 331 -10.818 -23.838 14.347 1.00 20.38 O ANISOU 1309 O HOH C 331 3721 1417 2605 -177 -673 481 O HETATM 1310 O HOH C 332 -20.115 -20.753 1.559 1.00 21.69 O ANISOU 1310 O HOH C 332 3413 3050 1778 -692 -439 191 O HETATM 1311 O HOH C 333 -4.688 16.131 17.179 1.00 20.45 O ANISOU 1311 O HOH C 333 2330 2496 2944 -855 552 234 O HETATM 1312 O HOH C 334 -13.232 -8.785 27.370 1.00 22.50 O ANISOU 1312 O HOH C 334 3353 2306 2890 -24 -279 69 O HETATM 1313 O HOH C 335 -10.549 -9.620 27.634 1.00 19.71 O ANISOU 1313 O HOH C 335 3009 2217 2261 -21 83 -184 O HETATM 1314 O HOH C 336 -7.948 -3.923 29.369 1.00 23.53 O ANISOU 1314 O HOH C 336 3639 2891 2409 -235 -924 983 O HETATM 1315 O HOH C 337 -11.977 6.223 24.995 1.00 23.94 O ANISOU 1315 O HOH C 337 3340 2384 3373 32 747 -70 O HETATM 1316 O HOH C 338 -15.311 -30.533 11.083 1.00 23.14 O ANISOU 1316 O HOH C 338 3437 2260 3096 136 270 -630 O HETATM 1317 O HOH C 339 -23.401 -24.844 5.804 1.00 22.93 O ANISOU 1317 O HOH C 339 2867 2801 3045 -1071 -603 -54 O HETATM 1318 O HOH C 340 -5.871 10.469 10.191 1.00 19.78 O ANISOU 1318 O HOH C 340 3211 1921 2385 -575 16 312 O HETATM 1319 O HOH C 341 -14.431 -30.150 17.492 1.00 26.61 O ANISOU 1319 O HOH C 341 2831 3614 3665 769 795 -284 O HETATM 1320 O HOH C 342 -16.787 -18.557 0.557 1.00 23.13 O ANISOU 1320 O HOH C 342 3493 2896 2398 -8 -621 -18 O HETATM 1321 O HOH C 343 -18.743 -10.273 23.506 1.00 18.15 O ANISOU 1321 O HOH C 343 2492 1332 3071 274 267 -416 O HETATM 1322 O HOH C 344 -16.464 -6.791 24.117 1.00 25.68 O ANISOU 1322 O HOH C 344 3015 3999 2742 -252 115 166 O HETATM 1323 O HOH C 345 -9.049 -14.068 20.171 1.00 8.32 O ANISOU 1323 O HOH C 345 1036 993 1134 -133 -86 -13 O HETATM 1324 O AHOH C 346 -12.031 10.605 18.403 0.62 7.38 O ANISOU 1324 O AHOH C 346 539 775 1491 129 -187 -121 O HETATM 1325 O BHOH C 346 -13.259 12.244 19.209 0.38 16.69 O ANISOU 1325 O BHOH C 346 1829 1815 2699 224 -86 487 O HETATM 1326 O AHOH C 347 -12.482 -8.596 18.430 0.52 9.83 O ANISOU 1326 O AHOH C 347 637 1144 1955 160 -308 -58 O HETATM 1327 O BHOH C 347 -12.195 -8.253 17.621 0.48 9.88 O ANISOU 1327 O BHOH C 347 1084 1316 1352 617 -557 -657 O HETATM 1328 O AHOH C 348 -14.891 -10.062 17.192 0.60 11.16 O ANISOU 1328 O AHOH C 348 1260 1125 1857 -34 195 -6 O HETATM 1329 O BHOH C 348 -15.772 -11.162 17.488 0.40 9.98 O ANISOU 1329 O BHOH C 348 1203 915 1675 113 -291 -87 O HETATM 1330 O AHOH C 349 -8.366 -13.464 15.695 0.44 7.35 O ANISOU 1330 O AHOH C 349 823 857 1114 -359 189 -186 O HETATM 1331 O BHOH C 349 -7.504 -13.696 14.786 0.56 10.10 O ANISOU 1331 O BHOH C 349 1069 1040 1727 -458 -90 -211 O HETATM 1332 O HOH C 350 -11.886 1.943 11.205 1.00 16.58 O ANISOU 1332 O HOH C 350 2421 1681 2199 -592 -494 468 O HETATM 1333 O HOH C 351 -3.506 9.012 26.265 1.00 21.72 O ANISOU 1333 O HOH C 351 3363 2683 2206 -1019 -308 205 O HETATM 1334 O HOH C 352 -11.052 10.953 20.698 1.00 18.80 O ANISOU 1334 O HOH C 352 2285 2267 2591 342 -459 -559 O HETATM 1335 O HOH C 353 -2.727 -5.442 22.392 1.00 22.39 O ANISOU 1335 O HOH C 353 2482 2941 3086 -1019 25 -525 O HETATM 1336 O HOH C 354 -12.477 14.594 18.493 1.00 22.48 O ANISOU 1336 O HOH C 354 2939 3344 2257 -281 281 -385 O HETATM 1337 O HOH C 355 -14.489 -10.944 27.409 1.00 21.36 O ANISOU 1337 O HOH C 355 2405 2106 3604 -51 964 -1182 O HETATM 1338 O AHOH C 356 -13.549 3.841 10.223 0.51 19.72 O ANISOU 1338 O AHOH C 356 2083 2582 2827 -371 -850 -121 O HETATM 1339 O BHOH C 356 -14.360 4.891 11.337 0.49 19.48 O ANISOU 1339 O BHOH C 356 2169 2856 2378 -339 -403 720 O HETATM 1340 O HOH C 357 -17.962 1.145 20.924 1.00 27.13 O ANISOU 1340 O HOH C 357 2812 4037 3459 -89 800 -418 O HETATM 1341 O HOH C 358 -16.003 -31.932 13.640 1.00 29.12 O ANISOU 1341 O HOH C 358 3491 3702 3873 -129 -6 58 O HETATM 1342 O HOH C 359 -6.424 12.828 12.911 1.00 22.70 O ANISOU 1342 O HOH C 359 3553 2772 2299 -433 29 362 O HETATM 1343 O HOH C 360 -3.688 -10.895 27.284 1.00 24.32 O ANISOU 1343 O HOH C 360 2683 3658 2899 -229 -1264 1024 O HETATM 1344 O HOH C 361 -4.254 -7.096 26.567 1.00 25.40 O ANISOU 1344 O HOH C 361 3346 2590 3717 178 -1371 -937 O HETATM 1345 O HOH C 362 -8.782 7.440 9.592 1.00 28.20 O ANISOU 1345 O HOH C 362 3512 3621 3581 -159 -725 753 O HETATM 1346 O HOH C 363 -9.026 -8.418 29.918 1.00 30.62 O ANISOU 1346 O HOH C 363 4200 3588 3845 -57 99 36 O HETATM 1347 O HOH C 364 0.507 -7.875 20.024 1.00 28.55 O ANISOU 1347 O HOH C 364 3102 3896 3850 -86 -67 175 O HETATM 1348 O AHOH C 365 -8.942 -6.669 11.683 0.67 13.58 O ANISOU 1348 O AHOH C 365 1125 2606 1429 -211 231 -650 O HETATM 1349 O BHOH C 365 -13.014 -5.506 15.871 0.33 13.57 O ANISOU 1349 O BHOH C 365 1322 2143 1689 -89 -906 -461 O HETATM 1350 O HOH C 366 -11.255 5.915 28.095 1.00 27.96 O ANISOU 1350 O HOH C 366 3955 3238 3431 344 88 -457 O HETATM 1351 O AHOH C 367 -4.266 -15.504 27.286 0.48 27.14 O ANISOU 1351 O AHOH C 367 3193 3656 3462 83 -90 -260 O HETATM 1352 O BHOH C 367 -3.981 -14.234 26.825 0.52 26.36 O ANISOU 1352 O BHOH C 367 3333 3574 3110 291 -333 144 O HETATM 1353 O HOH C 368 -10.638 -25.076 4.246 1.00 26.62 O ANISOU 1353 O HOH C 368 3430 3234 3451 489 693 -108 O HETATM 1354 O HOH C 369 -2.500 -6.256 24.726 1.00 28.12 O ANISOU 1354 O HOH C 369 3297 3181 4204 31 -633 -15 O HETATM 1355 O HOH C 370 -17.926 -3.033 21.487 1.00 26.03 O ANISOU 1355 O HOH C 370 3272 3020 3599 216 651 -727 O HETATM 1356 O AHOH C 371 -11.740 16.986 19.280 0.51 19.95 O ANISOU 1356 O AHOH C 371 2733 2466 2382 174 -631 49 O HETATM 1357 O BHOH C 371 -12.685 17.540 19.914 0.49 20.02 O ANISOU 1357 O BHOH C 371 2511 2720 2376 44 -711 282 O HETATM 1358 O HOH C 372 -16.110 -18.213 31.032 1.00 10.75 O ANISOU 1358 O HOH C 372 1728 1074 1282 210 153 22 O HETATM 1359 O HOH C 373 -16.968 -25.725 19.168 1.00 12.77 O ANISOU 1359 O HOH C 373 1384 1267 2202 -282 -777 379 O HETATM 1360 O HOH C 374 -19.329 -30.163 4.234 1.00 28.15 O ANISOU 1360 O HOH C 374 3641 3532 3523 83 -149 295 O HETATM 1361 O AHOH C 375 -11.178 3.647 29.199 0.57 17.79 O ANISOU 1361 O AHOH C 375 2551 2417 1793 768 965 121 O HETATM 1362 O BHOH C 375 -10.674 2.474 29.947 0.43 13.36 O ANISOU 1362 O BHOH C 375 1867 1132 2077 -402 196 -61 O HETATM 1363 O HOH C 376 -17.446 -31.749 8.431 1.00 27.34 O ANISOU 1363 O HOH C 376 3909 2749 3730 59 100 -156 O HETATM 1364 O HOH C 377 -24.441 -30.509 5.966 1.00 31.34 O ANISOU 1364 O HOH C 377 4256 3772 3881 -37 60 -431 O HETATM 1365 O HOH C 378 -15.477 -2.760 26.303 1.00 30.68 O ANISOU 1365 O HOH C 378 3796 3781 4081 -57 359 342 O HETATM 1366 O HOH C 379 -1.314 -13.064 25.361 1.00 30.84 O ANISOU 1366 O HOH C 379 4124 3635 3960 -128 -323 644 O HETATM 1367 O AHOH C 380 -8.260 -9.513 12.289 0.70 10.23 O ANISOU 1367 O AHOH C 380 880 1760 1248 -260 -27 -257 O HETATM 1368 O BHOH C 380 -7.584 -10.317 12.132 0.30 9.90 O ANISOU 1368 O BHOH C 380 1094 1319 1348 -156 10 22 O HETATM 1369 O AHOH C 381 -7.056 -4.320 11.125 0.48 9.52 O ANISOU 1369 O AHOH C 381 1309 1382 927 28 -35 -139 O HETATM 1370 O BHOH C 381 -5.718 -3.431 11.288 0.52 11.94 O ANISOU 1370 O BHOH C 381 1510 1769 1259 -249 381 119 O HETATM 1371 O HOH C 382 -21.953 -19.676 9.439 1.00 18.94 O ANISOU 1371 O HOH C 382 1952 1696 3549 -30 832 -274 O HETATM 1372 O HOH C 383 1.262 -3.516 17.615 1.00 26.58 O ANISOU 1372 O HOH C 383 3009 3081 4007 -250 37 331 O HETATM 1373 O AHOH C 384 -11.298 0.928 9.359 0.58 15.12 O ANISOU 1373 O AHOH C 384 1671 2368 1704 -312 -354 796 O HETATM 1374 O BHOH C 384 -11.997 0.334 8.920 0.42 14.55 O ANISOU 1374 O BHOH C 384 2130 1705 1692 -548 -926 -419 O HETATM 1375 O HOH C 385 -16.863 -29.594 15.236 1.00 16.92 O ANISOU 1375 O HOH C 385 2462 1929 2039 -403 364 6 O HETATM 1376 O HOH C 386 -13.336 -27.355 18.354 1.00 27.71 O ANISOU 1376 O HOH C 386 3804 3350 3374 -330 404 -349 O HETATM 1377 O HOH C 387 -14.808 -11.519 30.127 1.00 24.05 O ANISOU 1377 O HOH C 387 2764 2929 3442 139 677 -42 O HETATM 1378 O HOH C 388 -10.620 -23.278 2.105 1.00 31.33 O ANISOU 1378 O HOH C 388 4144 3805 3956 146 129 -527 O HETATM 1379 O HOH C 389 -11.627 9.851 15.831 1.00 20.27 O ANISOU 1379 O HOH C 389 2882 2201 2619 145 -848 -102 O HETATM 1380 O HOH C 390 -21.821 -33.025 21.411 1.00 21.88 O ANISOU 1380 O HOH C 390 3131 2767 2416 691 -662 -787 O HETATM 1381 O AHOH C 391 -13.247 9.926 20.215 0.42 21.53 O ANISOU 1381 O AHOH C 391 1873 2154 4153 -111 -886 481 O HETATM 1382 O BHOH C 391 -13.227 6.473 14.152 0.58 20.72 O ANISOU 1382 O BHOH C 391 1705 2033 4135 -173 -931 405 O HETATM 1383 O AHOH C 392 -8.683 7.264 26.550 0.62 23.80 O ANISOU 1383 O AHOH C 392 2818 3031 3195 232 -49 -177 O HETATM 1384 O BHOH C 392 -8.070 9.143 26.594 0.38 24.69 O ANISOU 1384 O BHOH C 392 3001 3115 3265 326 216 -212 O HETATM 1385 O HOH C 393 -21.713 -26.553 2.899 1.00 30.84 O ANISOU 1385 O HOH C 393 3734 3960 4025 -214 -403 -456 O HETATM 1386 O HOH C 394 -10.966 -21.122 18.911 1.00 21.19 O ANISOU 1386 O HOH C 394 3767 1699 2585 860 330 630 O HETATM 1387 O AHOH C 395 -13.987 -7.014 25.368 0.34 24.55 O ANISOU 1387 O AHOH C 395 3423 2903 3001 69 91 -319 O HETATM 1388 O BHOH C 395 -14.257 -4.520 23.227 0.14 27.33 O ANISOU 1388 O BHOH C 395 3628 3360 3396 127 11 -315 O HETATM 1389 O CHOH C 395 -14.514 -4.952 23.998 0.51 23.78 O ANISOU 1389 O CHOH C 395 3289 2799 2948 -7 283 -330 O HETATM 1390 O HOH C 396 -17.424 -23.094 19.643 1.00 16.87 O ANISOU 1390 O HOH C 396 1585 1882 2942 -266 -152 -58 O HETATM 1391 O HOH C 397 -15.496 -23.770 -3.190 1.00 31.11 O ANISOU 1391 O HOH C 397 3926 3998 3896 -17 0 -260 O HETATM 1392 O HOH C 398 0.915 -10.468 20.915 1.00 28.75 O ANISOU 1392 O HOH C 398 3468 3854 3600 236 116 -462 O HETATM 1393 O HOH C 399 -10.761 5.965 8.223 1.00 30.03 O ANISOU 1393 O HOH C 399 3616 3936 3857 309 298 132 O HETATM 1394 O HOH C 400 -2.450 -2.614 25.764 1.00 29.49 O ANISOU 1394 O HOH C 400 3700 3608 3897 -166 -123 158 O HETATM 1395 O HOH C 401 -4.479 -1.865 27.552 1.00 26.61 O ANISOU 1395 O HOH C 401 3800 3006 3306 -281 -308 431 O HETATM 1396 O HOH C 402 -10.810 -27.824 4.053 1.00 30.03 O ANISOU 1396 O HOH C 402 3918 3746 3745 11 193 -114 O CONECT 141 180 CONECT 142 181 CONECT 155 156 161 164 165 CONECT 156 155 157 162 CONECT 157 156 158 CONECT 158 157 159 163 CONECT 159 158 160 161 CONECT 160 159 CONECT 161 155 159 CONECT 162 156 CONECT 163 158 CONECT 164 155 166 172 CONECT 165 155 167 173 CONECT 166 164 168 CONECT 167 165 169 CONECT 168 166 170 174 CONECT 169 167 171 175 CONECT 170 168 172 176 CONECT 171 169 173 177 CONECT 172 164 170 CONECT 173 165 171 CONECT 174 168 186 CONECT 175 169 187 CONECT 176 170 178 CONECT 177 171 179 CONECT 178 176 180 CONECT 179 177 181 CONECT 180 141 178 182 184 CONECT 181 142 179 183 185 CONECT 182 180 CONECT 183 181 CONECT 184 180 CONECT 185 181 CONECT 186 174 CONECT 187 175 CONECT 387 418 CONECT 401 402 407 410 CONECT 402 401 403 408 CONECT 403 402 404 CONECT 404 403 405 409 CONECT 405 404 406 407 CONECT 406 405 CONECT 407 401 405 CONECT 408 402 CONECT 409 404 CONECT 410 401 411 414 CONECT 411 410 412 CONECT 412 411 413 415 CONECT 413 412 414 416 CONECT 414 410 413 CONECT 415 412 421 CONECT 416 413 417 CONECT 417 416 418 CONECT 418 387 417 419 420 CONECT 419 418 CONECT 420 418 CONECT 421 415 CONECT 618 1104 CONECT 654 1104 CONECT 761 1104 CONECT 798 1104 CONECT 863 1103 CONECT 891 1103 CONECT 1021 1103 CONECT 1059 1103 CONECT 1086 1109 1111 1193 1194 CONECT 1086 1196 1198 1199 CONECT 1087 1088 CONECT 1088 1087 1089 1090 1091 CONECT 1089 1088 CONECT 1090 1088 CONECT 1091 1088 1092 CONECT 1092 1091 1093 1094 CONECT 1093 1092 CONECT 1094 1092 CONECT 1095 1096 CONECT 1096 1095 1097 1098 1099 CONECT 1097 1096 CONECT 1098 1096 CONECT 1099 1096 1100 CONECT 1100 1099 1101 1102 CONECT 1101 1100 CONECT 1102 1100 CONECT 1103 863 891 1021 1059 CONECT 1104 618 654 761 798 CONECT 1105 1106 1107 1108 CONECT 1106 1105 CONECT 1107 1105 CONECT 1108 1105 CONECT 1109 1086 CONECT 1111 1086 CONECT 1193 1086 CONECT 1194 1086 CONECT 1196 1086 CONECT 1198 1086 CONECT 1199 1086 MASTER 351 0 8 3 4 0 10 6 1200 3 96 7 END
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Related entries of code: 4gzn
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
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Protein Sequence Similarity
No similar entries are found!
Complexes with the same small molecule ligand
PDB Code
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Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
4gzn
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
mouse Zfp57 fragment (residues 137-195) consisting of two fingers ZF2-3
Ligand Name
methylated DNA
EC.Number
E.C.-.-.-.-
Resolution
0.99(Å)
Affinity (Kd/Ki/IC50)
Kd=8nM
Release Year
2012
Protein/NA Sequence
Check fasta file
Primary Reference
(2012) Genes Dev. Vol. 26: pp. 2374-2379
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q8C6P8
Entrez Gene ID
NCBI Entrez Gene ID:
22715
ASD
Information of known allosteric effects of PDB entries
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娌狪CP澶2021015625鍙-3
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