Browse entries in the PDBbind-CN Database
HEADER DNA BINDING PROTEIN 11-OCT-12 4HIO TITLE CRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE POT1PC BOUND TO SSDNA TITLE 2 (GGTAACGGT) COMPND MOL_ID: 1; COMPND 2 MOLECULE: PROTECTION OF TELOMERES PROTEIN 1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: POT1PC, PARTIAL DNA BINDING DOMAIN, RESIDUES 198-339; COMPND 5 ENGINEERED: YES; COMPND 6 MUTATION: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*GP*GP*TP*AP*AP*CP*GP*GP*T)-3'); COMPND 9 CHAIN: B; COMPND 10 ENGINEERED: YES; COMPND 11 OTHER_DETAILS: TELOMERIC SINGLE-STRANDED DNA, T4A VARIANT SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE; SOURCE 3 ORGANISM_COMMON: FISSION YEAST; SOURCE 4 ORGANISM_TAXID: 284812; SOURCE 5 STRAIN: 972H-; SOURCE 6 GENE: POT1, SPAC26H5.06; SOURCE 7 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 8 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 9 EXPRESSION_SYSTEM_STRAIN: BL21 (DE3); SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PTXB1; SOURCE 12 MOL_ID: 2; SOURCE 13 SYNTHETIC: YES; SOURCE 14 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE; SOURCE 15 ORGANISM_TAXID: 284812 KEYWDS SPECIFICITY, PLASTICITY, PROMISCUITY, OB-FOLD, SSDNA-BINDING, SINGLE- KEYWDS 2 STRANDED TELOMERIC DNA, DNA BINDING PROTEIN EXPDTA X-RAY DIFFRACTION AUTHOR T.H.DICKEY,M.A.MCKERCHER,D.S.WUTTKE REVDAT 3 15-NOV-17 4HIO 1 REMARK REVDAT 2 27-FEB-13 4HIO 1 JRNL REVDAT 1 12-DEC-12 4HIO 0 JRNL AUTH T.H.DICKEY,M.A.MCKERCHER,D.S.WUTTKE JRNL TITL NONSPECIFIC RECOGNITION IS ACHIEVED IN POT1PC THROUGH THE JRNL TITL 2 USE OF MULTIPLE BINDING MODES. JRNL REF STRUCTURE V. 21 121 2013 JRNL REFN ISSN 0969-2126 JRNL PMID 23201273 JRNL DOI 10.1016/J.STR.2012.10.015 REMARK 2 REMARK 2 RESOLUTION. 1.75 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX 1.7_650 REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ENGH & HUBER REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.75 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 30.26 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 96.1 REMARK 3 NUMBER OF REFLECTIONS : 16430 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.217 REMARK 3 R VALUE (WORKING SET) : 0.215 REMARK 3 FREE R VALUE : 0.236 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 9.990 REMARK 3 FREE R VALUE TEST SET COUNT : 1641 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 30.2689 - 4.0114 0.99 1373 153 0.1981 0.2347 REMARK 3 2 4.0114 - 3.1851 1.00 1290 144 0.1788 0.2049 REMARK 3 3 3.1851 - 2.7828 0.99 1293 143 0.2264 0.2182 REMARK 3 4 2.7828 - 2.5285 0.99 1273 142 0.2220 0.2474 REMARK 3 5 2.5285 - 2.3473 0.98 1250 139 0.2204 0.2221 REMARK 3 6 2.3473 - 2.2090 0.98 1245 138 0.2219 0.2483 REMARK 3 7 2.2090 - 2.0984 0.97 1246 137 0.2259 0.2706 REMARK 3 8 2.0984 - 2.0071 0.97 1224 136 0.2148 0.2291 REMARK 3 9 2.0071 - 1.9298 0.96 1206 136 0.2243 0.2567 REMARK 3 10 1.9298 - 1.8632 0.95 1187 133 0.2428 0.2674 REMARK 3 11 1.8632 - 1.8050 0.92 1181 130 0.2692 0.2708 REMARK 3 12 1.8050 - 1.7534 0.81 1021 110 0.3221 0.3175 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 0.40 REMARK 3 SHRINKAGE RADIUS : 0.04 REMARK 3 K_SOL : 0.43 REMARK 3 B_SOL : 57.01 REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.150 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 21.340 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 21.59 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 1.47520 REMARK 3 B22 (A**2) : -2.07840 REMARK 3 B33 (A**2) : -2.07280 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.009 1419 REMARK 3 ANGLE : 0.877 1956 REMARK 3 CHIRALITY : 0.061 202 REMARK 3 PLANARITY : 0.005 216 REMARK 3 DIHEDRAL : 18.754 536 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 4HIO COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 18-OCT-12. REMARK 100 THE DEPOSITION ID IS D_1000075514. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 04-JAN-12 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 7 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : N REMARK 200 RADIATION SOURCE : ROTATING ANODE REMARK 200 BEAMLINE : NULL REMARK 200 X-RAY GENERATOR MODEL : RIGAKU RUH2R REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.54 REMARK 200 MONOCHROMATOR : OSMIC MIRRORS REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : IMAGE PLATE REMARK 200 DETECTOR MANUFACTURER : RIGAKU RAXIS IV++ REMARK 200 INTENSITY-INTEGRATION SOFTWARE : DENZO, HKL-2000 REMARK 200 DATA SCALING SOFTWARE : SCALEPACK, HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 16782 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.753 REMARK 200 RESOLUTION RANGE LOW (A) : 50.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : -3.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 98.5 REMARK 200 DATA REDUNDANCY : 3.300 REMARK 200 R MERGE (I) : 0.05700 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 12.0000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.76 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.82 REMARK 200 COMPLETENESS FOR SHELL (%) : 95.7 REMARK 200 DATA REDUNDANCY IN SHELL : 3.00 REMARK 200 R MERGE FOR SHELL (I) : 0.36600 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX 1.7_650 REMARK 200 STARTING MODEL: 4HIK REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 40.08 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.05 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 30% PEG 6000, 0.2M SODIUM FORMATE, PH REMARK 280 7, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 290K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X+1/2,-Y,Z+1/2 REMARK 290 3555 -X,Y+1/2,-Z+1/2 REMARK 290 4555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 20.67000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 33.14100 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 29.93300 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 33.14100 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 20.67000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 29.93300 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2150 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 8430 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -3.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 SER A 2 REMARK 465 GLN A 142 REMARK 465 ASN A 143 REMARK 480 REMARK 480 ZERO OCCUPANCY ATOM REMARK 480 THE FOLLOWING RESIDUES HAVE ATOMS MODELED WITH ZERO REMARK 480 OCCUPANCY. THE LOCATION AND PROPERTIES OF THESE ATOMS REMARK 480 MAY NOT BE RELIABLE. (M=MODEL NUMBER; RES=RESIDUE NAME; REMARK 480 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 480 M RES C SSEQI ATOMS REMARK 480 ASP A 3 CB CG OD1 OD2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O HOH A 289 O HOH A 332 1.87 REMARK 500 OD1 ASN A 117 O HOH A 279 2.00 REMARK 500 O HOH A 231 O HOH A 350 2.03 REMARK 500 OP2 DG B 8 O HOH B 110 2.12 REMARK 500 O HOH B 116 O HOH B 121 2.13 REMARK 500 O HOH A 255 O HOH B 122 2.13 REMARK 500 O ARG A 57 NE ARG A 59 2.19 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 O HOH A 268 O HOH A 290 2565 2.12 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DG B 2 O4' - C1' - N9 ANGL. DEV. = 2.4 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASP A 73 -123.34 53.95 REMARK 500 TYR A 82 -54.68 -140.81 REMARK 500 ASP A 111 69.35 -157.57 REMARK 500 REMARK 500 REMARK: NULL REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 4HIM RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HIK RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HID RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HJ5 RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HJ7 RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HJ8 RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HJ9 RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE REMARK 900 RELATED ID: 4HJA RELATED DB: PDB REMARK 900 THE SAME PROTEIN BOUND TO A DIFFERENT SSDNA SEQUENCE DBREF 4HIO A 2 143 UNP O13988 POT1_SCHPO 198 339 DBREF 4HIO B 1 9 PDB 4HIO 4HIO 1 9 SEQADV 4HIO MET A 1 UNP O13988 EXPRESSION TAG SEQADV 4HIO ASP A 3 UNP O13988 VAL 199 ENGINEERED MUTATION SEQRES 1 A 143 MET SER ASP SER PHE SER LEU LEU SER GLN ILE THR PRO SEQRES 2 A 143 HIS GLN ARG CYS SER PHE TYR ALA GLN VAL ILE LYS THR SEQRES 3 A 143 TRP TYR SER ASP LYS ASN PHE THR LEU TYR VAL THR ASP SEQRES 4 A 143 TYR THR GLU ASN GLU LEU PHE PHE PRO MET SER PRO TYR SEQRES 5 A 143 THR SER SER SER ARG TRP ARG GLY PRO PHE GLY ARG PHE SEQRES 6 A 143 SER ILE ARG CYS ILE LEU TRP ASP GLU HIS ASP PHE TYR SEQRES 7 A 143 CYS ARG ASN TYR ILE LYS GLU GLY ASP TYR VAL VAL MET SEQRES 8 A 143 LYS ASN VAL ARG THR LYS ILE ASP HIS LEU GLY TYR LEU SEQRES 9 A 143 GLU CYS ILE LEU HIS GLY ASP SER ALA LYS ARG TYR ASN SEQRES 10 A 143 MET SER ILE GLU LYS VAL ASP SER GLU GLU PRO GLU LEU SEQRES 11 A 143 ASN GLU ILE LYS SER ARG LYS ARG LEU TYR VAL GLN ASN SEQRES 1 B 9 DG DG DT DA DA DC DG DG DT FORMUL 3 HOH *192(H2 O) HELIX 1 1 ASP A 73 ARG A 80 1 8 HELIX 2 2 GLU A 127 GLU A 129 5 3 HELIX 3 3 LEU A 130 VAL A 141 1 12 SHEET 1 A 7 SER A 119 VAL A 123 0 SHEET 2 A 7 TYR A 88 ILE A 98 -1 N TYR A 88 O VAL A 123 SHEET 3 A 7 LEU A 104 LEU A 108 -1 O ILE A 107 N ARG A 95 SHEET 4 A 7 ILE A 67 LEU A 71 1 N ARG A 68 O CYS A 106 SHEET 5 A 7 PHE A 33 THR A 38 -1 N LEU A 35 O CYS A 69 SHEET 6 A 7 CYS A 17 TYR A 28 -1 N GLN A 22 O THR A 38 SHEET 7 A 7 TYR A 88 ILE A 98 -1 O MET A 91 N PHE A 19 CRYST1 41.340 59.866 66.282 90.00 90.00 90.00 P 21 21 21 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.024190 0.000000 0.000000 0.00000 SCALE2 0.000000 0.016704 0.000000 0.00000 SCALE3 0.000000 0.000000 0.015087 0.00000 ATOM 1 N ASP A 3 6.780 8.537 9.805 1.00 52.35 N ATOM 2 CA ASP A 3 6.966 8.741 11.236 1.00 46.34 C ATOM 3 C ASP A 3 5.684 9.216 11.912 1.00 49.56 C ATOM 4 O ASP A 3 4.668 9.434 11.256 1.00 53.89 O ATOM 5 CB ASP A 3 8.089 9.746 11.489 0.00 48.00 C ATOM 6 CG ASP A 3 8.983 9.935 10.283 0.00 48.31 C ATOM 7 OD1 ASP A 3 8.570 10.636 9.337 0.00 49.01 O ATOM 8 OD2 ASP A 3 10.098 9.380 10.277 0.00 48.03 O ATOM 9 N SER A 4 5.741 9.374 13.230 1.00 43.70 N ATOM 10 CA SER A 4 4.598 9.860 13.989 1.00 39.76 C ATOM 11 C SER A 4 4.954 11.164 14.687 1.00 30.53 C ATOM 12 O SER A 4 6.125 11.516 14.812 1.00 29.35 O ATOM 13 CB SER A 4 4.142 8.824 15.012 1.00 39.20 C ATOM 14 OG SER A 4 5.230 8.381 15.799 1.00 45.21 O ATOM 15 N PHE A 5 3.935 11.879 15.137 1.00 26.28 N ATOM 16 CA PHE A 5 4.148 13.180 15.746 1.00 23.42 C ATOM 17 C PHE A 5 4.308 13.099 17.257 1.00 22.16 C ATOM 18 O PHE A 5 3.747 12.224 17.902 1.00 23.92 O ATOM 19 CB PHE A 5 2.999 14.125 15.381 1.00 22.22 C ATOM 20 CG PHE A 5 2.937 14.464 13.917 1.00 24.12 C ATOM 21 CD1 PHE A 5 2.068 13.796 13.071 1.00 29.60 C ATOM 22 CD2 PHE A 5 3.755 15.438 13.384 1.00 19.19 C ATOM 23 CE1 PHE A 5 2.016 14.106 11.730 1.00 25.58 C ATOM 24 CE2 PHE A 5 3.707 15.742 12.048 1.00 19.79 C ATOM 25 CZ PHE A 5 2.834 15.077 11.220 1.00 26.01 C ATOM 26 N SER A 6 5.093 14.023 17.802 1.00 20.11 N ATOM 27 CA SER A 6 5.260 14.158 19.239 1.00 16.81 C ATOM 28 C SER A 6 4.770 15.529 19.678 1.00 18.58 C ATOM 29 O SER A 6 4.859 16.499 18.928 1.00 18.10 O ATOM 30 CB SER A 6 6.736 14.037 19.631 1.00 18.70 C ATOM 31 OG SER A 6 7.301 12.801 19.250 1.00 21.86 O ATOM 32 N LEU A 7 4.271 15.606 20.903 1.00 16.11 N ATOM 33 CA LEU A 7 4.084 16.879 21.561 1.00 16.81 C ATOM 34 C LEU A 7 5.478 17.358 21.940 1.00 16.93 C ATOM 35 O LEU A 7 6.390 16.560 22.086 1.00 17.84 O ATOM 36 CB LEU A 7 3.217 16.723 22.806 1.00 15.50 C ATOM 37 CG LEU A 7 1.801 16.211 22.560 1.00 20.06 C ATOM 38 CD1 LEU A 7 0.997 16.253 23.841 1.00 16.32 C ATOM 39 CD2 LEU A 7 1.120 17.014 21.473 1.00 21.49 C ATOM 40 N LEU A 8 5.644 18.664 22.080 1.00 13.71 N ATOM 41 CA LEU A 8 6.949 19.230 22.373 1.00 13.50 C ATOM 42 C LEU A 8 7.399 18.877 23.783 1.00 15.05 C ATOM 43 O LEU A 8 8.589 18.873 24.077 1.00 15.40 O ATOM 44 CB LEU A 8 6.938 20.745 22.166 1.00 14.29 C ATOM 45 CG LEU A 8 7.089 21.187 20.708 1.00 15.57 C ATOM 46 CD1 LEU A 8 7.248 22.695 20.602 1.00 16.12 C ATOM 47 CD2 LEU A 8 8.262 20.478 20.060 1.00 16.30 C ATOM 48 N SER A 9 6.438 18.574 24.650 1.00 15.77 N ATOM 49 CA SER A 9 6.742 18.029 25.966 1.00 14.46 C ATOM 50 C SER A 9 7.540 16.732 25.871 1.00 18.59 C ATOM 51 O SER A 9 8.259 16.369 26.798 1.00 18.62 O ATOM 52 CB SER A 9 5.460 17.797 26.762 1.00 18.73 C ATOM 53 OG SER A 9 4.634 16.838 26.136 1.00 16.70 O ATOM 54 N GLN A 10 7.407 16.038 24.746 1.00 16.85 N ATOM 55 CA GLN A 10 7.835 14.648 24.660 1.00 17.09 C ATOM 56 C GLN A 10 9.200 14.504 23.988 1.00 21.04 C ATOM 57 O GLN A 10 9.839 13.461 24.095 1.00 22.92 O ATOM 58 CB GLN A 10 6.787 13.807 23.925 1.00 18.76 C ATOM 59 CG GLN A 10 5.554 13.493 24.752 1.00 27.46 C ATOM 60 CD GLN A 10 4.344 13.149 23.904 1.00 32.31 C ATOM 61 OE1 GLN A 10 4.472 12.750 22.749 1.00 31.03 O ATOM 62 NE2 GLN A 10 3.157 13.305 24.478 1.00 36.07 N ATOM 63 N ILE A 11 9.650 15.545 23.293 1.00 16.72 N ATOM 64 CA ILE A 11 10.883 15.433 22.520 1.00 19.25 C ATOM 65 C ILE A 11 12.135 15.408 23.397 1.00 20.27 C ATOM 66 O ILE A 11 12.142 15.925 24.511 1.00 18.79 O ATOM 67 CB ILE A 11 11.016 16.532 21.434 1.00 17.75 C ATOM 68 CG1 ILE A 11 11.272 17.897 22.064 1.00 15.80 C ATOM 69 CG2 ILE A 11 9.789 16.559 20.539 1.00 18.42 C ATOM 70 CD1 ILE A 11 11.716 18.947 21.067 1.00 19.38 C ATOM 71 N THR A 12 13.202 14.830 22.864 1.00 17.25 N ATOM 72 CA THR A 12 14.455 14.698 23.588 1.00 17.69 C ATOM 73 C THR A 12 15.606 15.065 22.665 1.00 21.75 C ATOM 74 O THR A 12 15.442 15.067 21.452 1.00 20.64 O ATOM 75 CB THR A 12 14.648 13.262 24.089 1.00 19.23 C ATOM 76 OG1 THR A 12 14.723 12.373 22.972 1.00 22.91 O ATOM 77 CG2 THR A 12 13.480 12.852 24.962 1.00 23.78 C ATOM 78 N PRO A 13 16.765 15.380 23.236 1.00 20.00 N ATOM 79 CA PRO A 13 17.899 15.826 22.422 1.00 18.44 C ATOM 80 C PRO A 13 18.503 14.701 21.586 1.00 19.72 C ATOM 81 O PRO A 13 18.511 13.544 22.001 1.00 19.86 O ATOM 82 CB PRO A 13 18.917 16.316 23.460 1.00 20.98 C ATOM 83 CG PRO A 13 18.172 16.403 24.750 1.00 18.45 C ATOM 84 CD PRO A 13 17.080 15.402 24.671 1.00 19.98 C ATOM 85 N HIS A 14 19.007 15.059 20.411 1.00 18.15 N ATOM 86 CA HIS A 14 19.728 14.128 19.556 1.00 19.35 C ATOM 87 C HIS A 14 18.851 12.942 19.166 1.00 19.36 C ATOM 88 O HIS A 14 19.350 11.866 18.853 1.00 21.37 O ATOM 89 CB HIS A 14 21.007 13.656 20.242 1.00 22.84 C ATOM 90 CG HIS A 14 21.786 14.761 20.883 1.00 20.99 C ATOM 91 ND1 HIS A 14 21.708 15.041 22.229 1.00 24.44 N ATOM 92 CD2 HIS A 14 22.652 15.660 20.360 1.00 27.90 C ATOM 93 CE1 HIS A 14 22.497 16.062 22.510 1.00 26.49 C ATOM 94 NE2 HIS A 14 23.080 16.458 21.393 1.00 25.31 N ATOM 95 N GLN A 15 17.562 13.239 19.031 1.00 21.18 N ATOM 96 CA GLN A 15 16.581 12.369 18.401 1.00 20.47 C ATOM 97 C GLN A 15 15.711 13.210 17.466 1.00 25.27 C ATOM 98 O GLN A 15 15.125 14.199 17.899 1.00 26.07 O ATOM 99 CB GLN A 15 15.693 11.725 19.459 1.00 22.98 C ATOM 100 CG GLN A 15 16.453 10.952 20.504 1.00 25.86 C ATOM 101 CD GLN A 15 16.343 9.463 20.297 1.00 32.41 C ATOM 102 OE1 GLN A 15 15.858 9.009 19.267 1.00 38.23 O ATOM 103 NE2 GLN A 15 16.790 8.693 21.277 1.00 35.14 N ATOM 104 N ARG A 16 15.627 12.830 16.193 1.00 16.60 N ATOM 105 CA ARG A 16 14.805 13.574 15.251 1.00 17.07 C ATOM 106 C ARG A 16 13.343 13.430 15.636 1.00 19.13 C ATOM 107 O ARG A 16 12.934 12.404 16.168 1.00 18.36 O ATOM 108 CB ARG A 16 15.034 13.081 13.828 1.00 18.51 C ATOM 109 CG ARG A 16 16.490 13.023 13.446 1.00 17.91 C ATOM 110 CD ARG A 16 16.683 12.878 11.951 1.00 18.79 C ATOM 111 NE ARG A 16 18.007 13.341 11.564 1.00 21.29 N ATOM 112 CZ ARG A 16 18.242 14.466 10.901 1.00 19.77 C ATOM 113 NH1 ARG A 16 17.234 15.240 10.530 1.00 18.95 N ATOM 114 NH2 ARG A 16 19.484 14.812 10.601 1.00 18.38 N ATOM 115 N CYS A 17 12.561 14.466 15.369 1.00 15.27 N ATOM 116 CA CYS A 17 11.176 14.498 15.807 1.00 17.80 C ATOM 117 C CYS A 17 10.299 15.269 14.833 1.00 14.84 C ATOM 118 O CYS A 17 10.792 15.995 13.974 1.00 16.78 O ATOM 119 CB CYS A 17 11.063 15.094 17.213 1.00 19.27 C ATOM 120 SG CYS A 17 11.671 16.779 17.360 1.00 23.32 S ATOM 121 N SER A 18 8.995 15.078 14.967 1.00 15.71 N ATOM 122 CA SER A 18 8.021 15.761 14.131 1.00 15.15 C ATOM 123 C SER A 18 6.899 16.283 15.012 1.00 15.43 C ATOM 124 O SER A 18 6.502 15.625 15.965 1.00 15.77 O ATOM 125 CB SER A 18 7.468 14.810 13.077 1.00 15.64 C ATOM 126 OG SER A 18 8.505 14.332 12.242 1.00 17.54 O ATOM 127 N PHE A 19 6.392 17.466 14.689 1.00 15.47 N ATOM 128 CA PHE A 19 5.400 18.105 15.535 1.00 14.90 C ATOM 129 C PHE A 19 4.698 19.270 14.851 1.00 15.96 C ATOM 130 O PHE A 19 5.229 19.874 13.925 1.00 13.68 O ATOM 131 CB PHE A 19 6.080 18.613 16.804 1.00 13.81 C ATOM 132 CG PHE A 19 7.205 19.575 16.540 1.00 16.78 C ATOM 133 CD1 PHE A 19 6.944 20.890 16.219 1.00 17.67 C ATOM 134 CD2 PHE A 19 8.520 19.160 16.596 1.00 14.33 C ATOM 135 CE1 PHE A 19 7.966 21.774 15.973 1.00 15.15 C ATOM 136 CE2 PHE A 19 9.548 20.042 16.347 1.00 15.76 C ATOM 137 CZ PHE A 19 9.268 21.351 16.038 1.00 16.14 C ATOM 138 N TYR A 20 3.501 19.581 15.332 1.00 13.66 N ATOM 139 CA TYR A 20 2.815 20.809 14.967 1.00 13.52 C ATOM 140 C TYR A 20 3.152 21.860 16.024 1.00 15.39 C ATOM 141 O TYR A 20 3.311 21.538 17.194 1.00 13.91 O ATOM 142 CB TYR A 20 1.300 20.600 14.945 1.00 17.77 C ATOM 143 CG TYR A 20 0.813 19.628 13.900 1.00 15.09 C ATOM 144 CD1 TYR A 20 0.677 20.012 12.579 1.00 17.12 C ATOM 145 CD2 TYR A 20 0.481 18.328 14.239 1.00 22.71 C ATOM 146 CE1 TYR A 20 0.235 19.127 11.623 1.00 17.67 C ATOM 147 CE2 TYR A 20 0.031 17.437 13.292 1.00 22.54 C ATOM 148 CZ TYR A 20 -0.085 17.841 11.984 1.00 24.52 C ATOM 149 OH TYR A 20 -0.530 16.953 11.044 1.00 25.26 O ATOM 150 N ALA A 21 3.250 23.117 15.617 1.00 15.51 N ATOM 151 CA ALA A 21 3.436 24.198 16.577 1.00 13.25 C ATOM 152 C ALA A 21 2.946 25.537 16.028 1.00 16.71 C ATOM 153 O ALA A 21 2.728 25.685 14.829 1.00 15.27 O ATOM 154 CB ALA A 21 4.889 24.288 16.990 1.00 13.52 C ATOM 155 N GLN A 22 2.774 26.506 16.922 1.00 14.55 N ATOM 156 CA GLN A 22 2.618 27.900 16.527 1.00 13.91 C ATOM 157 C GLN A 22 3.924 28.678 16.621 1.00 16.78 C ATOM 158 O GLN A 22 4.641 28.595 17.613 1.00 13.76 O ATOM 159 CB GLN A 22 1.538 28.589 17.362 1.00 15.42 C ATOM 160 CG GLN A 22 1.183 29.976 16.859 1.00 15.47 C ATOM 161 CD GLN A 22 -0.124 30.487 17.426 1.00 15.68 C ATOM 162 OE1 GLN A 22 -0.479 30.186 18.563 1.00 15.59 O ATOM 163 NE2 GLN A 22 -0.848 31.265 16.630 1.00 17.50 N ATOM 164 N VAL A 23 4.220 29.433 15.570 1.00 12.85 N ATOM 165 CA VAL A 23 5.342 30.360 15.567 1.00 13.93 C ATOM 166 C VAL A 23 5.044 31.601 16.402 1.00 12.30 C ATOM 167 O VAL A 23 4.068 32.303 16.160 1.00 16.50 O ATOM 168 CB VAL A 23 5.705 30.788 14.135 1.00 12.42 C ATOM 169 CG1 VAL A 23 6.826 31.810 14.153 1.00 12.25 C ATOM 170 CG2 VAL A 23 6.092 29.577 13.306 1.00 12.99 C ATOM 171 N ILE A 24 5.892 31.842 17.394 1.00 11.41 N ATOM 172 CA ILE A 24 5.764 33.015 18.243 1.00 14.80 C ATOM 173 C ILE A 24 6.673 34.136 17.748 1.00 15.91 C ATOM 174 O ILE A 24 6.258 35.284 17.665 1.00 15.13 O ATOM 175 CB ILE A 24 6.106 32.693 19.711 1.00 12.90 C ATOM 176 CG1 ILE A 24 5.237 31.541 20.221 1.00 14.20 C ATOM 177 CG2 ILE A 24 5.922 33.920 20.580 1.00 16.23 C ATOM 178 CD1 ILE A 24 3.755 31.834 20.224 1.00 10.94 C ATOM 179 N LYS A 25 7.912 33.786 17.419 1.00 11.49 N ATOM 180 CA LYS A 25 8.890 34.765 16.983 1.00 12.19 C ATOM 181 C LYS A 25 9.693 34.285 15.787 1.00 13.95 C ATOM 182 O LYS A 25 10.058 33.122 15.701 1.00 14.04 O ATOM 183 CB LYS A 25 9.848 35.110 18.119 1.00 14.89 C ATOM 184 CG LYS A 25 10.744 36.297 17.820 1.00 16.63 C ATOM 185 CD LYS A 25 12.022 36.254 18.630 1.00 19.19 C ATOM 186 CE LYS A 25 13.016 37.293 18.146 1.00 17.92 C ATOM 187 NZ LYS A 25 13.607 38.049 19.276 1.00 17.38 N ATOM 188 N THR A 26 9.971 35.205 14.873 1.00 13.61 N ATOM 189 CA THR A 26 10.897 34.951 13.783 1.00 12.66 C ATOM 190 C THR A 26 12.030 35.968 13.788 1.00 15.12 C ATOM 191 O THR A 26 11.839 37.112 14.179 1.00 15.55 O ATOM 192 CB THR A 26 10.180 35.007 12.429 1.00 15.86 C ATOM 193 OG1 THR A 26 9.798 36.356 12.143 1.00 15.29 O ATOM 194 CG2 THR A 26 8.940 34.123 12.450 1.00 13.14 C ATOM 195 N TRP A 27 13.207 35.541 13.346 1.00 11.25 N ATOM 196 CA TRP A 27 14.290 36.464 13.031 1.00 13.45 C ATOM 197 C TRP A 27 15.196 35.909 11.934 1.00 13.61 C ATOM 198 O TRP A 27 15.822 34.869 12.110 1.00 12.03 O ATOM 199 CB TRP A 27 15.119 36.758 14.282 1.00 14.76 C ATOM 200 CG TRP A 27 16.112 37.838 14.067 1.00 16.04 C ATOM 201 CD1 TRP A 27 17.457 37.698 13.937 1.00 17.56 C ATOM 202 CD2 TRP A 27 15.835 39.233 13.927 1.00 18.93 C ATOM 203 NE1 TRP A 27 18.041 38.924 13.734 1.00 17.37 N ATOM 204 CE2 TRP A 27 17.063 39.883 13.724 1.00 17.50 C ATOM 205 CE3 TRP A 27 14.665 39.996 13.956 1.00 16.90 C ATOM 206 CZ2 TRP A 27 17.157 41.257 13.553 1.00 18.77 C ATOM 207 CZ3 TRP A 27 14.761 41.354 13.788 1.00 16.53 C ATOM 208 CH2 TRP A 27 15.998 41.974 13.590 1.00 18.00 C ATOM 209 N TYR A 28 15.269 36.604 10.805 1.00 14.24 N ATOM 210 CA TYR A 28 16.238 36.241 9.777 1.00 15.34 C ATOM 211 C TYR A 28 17.537 37.026 9.909 1.00 15.64 C ATOM 212 O TYR A 28 17.534 38.195 10.277 1.00 16.47 O ATOM 213 CB TYR A 28 15.648 36.385 8.370 1.00 16.25 C ATOM 214 CG TYR A 28 15.331 37.801 7.945 1.00 19.91 C ATOM 215 CD1 TYR A 28 16.327 38.651 7.482 1.00 22.03 C ATOM 216 CD2 TYR A 28 14.033 38.279 7.988 1.00 15.77 C ATOM 217 CE1 TYR A 28 16.034 39.939 7.088 1.00 18.92 C ATOM 218 CE2 TYR A 28 13.733 39.557 7.597 1.00 22.49 C ATOM 219 CZ TYR A 28 14.734 40.387 7.149 1.00 24.42 C ATOM 220 OH TYR A 28 14.425 41.670 6.758 1.00 21.53 O ATOM 221 N SER A 29 18.644 36.355 9.617 1.00 15.22 N ATOM 222 CA SER A 29 19.961 36.965 9.677 1.00 19.12 C ATOM 223 C SER A 29 20.766 36.589 8.440 1.00 20.10 C ATOM 224 O SER A 29 20.290 35.855 7.580 1.00 18.07 O ATOM 225 CB SER A 29 20.701 36.517 10.936 1.00 20.93 C ATOM 226 OG SER A 29 21.186 35.195 10.797 1.00 20.21 O ATOM 227 N ASP A 30 21.989 37.093 8.364 1.00 19.93 N ATOM 228 CA ASP A 30 22.847 36.847 7.215 1.00 22.78 C ATOM 229 C ASP A 30 23.374 35.416 7.181 1.00 21.71 C ATOM 230 O ASP A 30 24.062 35.026 6.243 1.00 24.57 O ATOM 231 CB ASP A 30 24.014 37.835 7.202 1.00 28.25 C ATOM 232 CG ASP A 30 24.884 37.726 8.435 1.00 30.48 C ATOM 233 OD1 ASP A 30 24.379 37.291 9.485 1.00 35.27 O ATOM 234 OD2 ASP A 30 26.076 38.081 8.354 1.00 40.59 O ATOM 235 N LYS A 31 23.076 34.651 8.217 1.00 20.00 N ATOM 236 CA LYS A 31 23.576 33.288 8.384 1.00 20.34 C ATOM 237 C LYS A 31 22.459 32.236 8.326 1.00 17.65 C ATOM 238 O LYS A 31 22.653 31.182 7.801 1.00 17.48 O ATOM 239 CB LYS A 31 24.312 33.151 9.705 1.00 22.00 C ATOM 240 CG LYS A 31 25.618 33.950 9.805 1.00 28.81 C ATOM 241 CD LYS A 31 26.572 33.520 8.715 1.00 34.03 C ATOM 242 CE LYS A 31 27.869 34.387 8.679 1.00 39.10 C ATOM 243 NZ LYS A 31 28.500 34.505 10.036 1.00 39.31 N ATOM 244 N ASN A 32 21.318 32.562 8.921 1.00 15.85 N ATOM 245 CA ASN A 32 20.214 31.618 9.027 1.00 14.60 C ATOM 246 C ASN A 32 18.860 32.287 9.273 1.00 16.79 C ATOM 247 O ASN A 32 18.756 33.510 9.311 1.00 14.95 O ATOM 248 CB ASN A 32 20.502 30.580 10.112 1.00 15.25 C ATOM 249 CG ASN A 32 20.966 31.207 11.411 1.00 17.66 C ATOM 250 OD1 ASN A 32 20.367 32.158 11.902 1.00 17.17 O ATOM 251 ND2 ASN A 32 22.044 30.672 11.975 1.00 20.07 N ATOM 252 N PHE A 33 17.831 31.462 9.434 1.00 14.48 N ATOM 253 CA PHE A 33 16.503 31.919 9.818 1.00 13.72 C ATOM 254 C PHE A 33 16.074 31.212 11.097 1.00 13.54 C ATOM 255 O PHE A 33 16.068 29.991 11.161 1.00 13.08 O ATOM 256 CB PHE A 33 15.506 31.612 8.704 1.00 11.47 C ATOM 257 CG PHE A 33 14.122 32.143 8.954 1.00 10.04 C ATOM 258 CD1 PHE A 33 13.922 33.470 9.284 1.00 9.93 C ATOM 259 CD2 PHE A 33 13.022 31.312 8.845 1.00 12.06 C ATOM 260 CE1 PHE A 33 12.654 33.955 9.504 1.00 12.26 C ATOM 261 CE2 PHE A 33 11.754 31.792 9.064 1.00 12.88 C ATOM 262 CZ PHE A 33 11.569 33.117 9.391 1.00 10.82 C ATOM 263 N THR A 34 15.721 31.983 12.117 1.00 12.03 N ATOM 264 CA THR A 34 15.433 31.406 13.423 1.00 11.76 C ATOM 265 C THR A 34 13.964 31.570 13.779 1.00 13.34 C ATOM 266 O THR A 34 13.404 32.655 13.654 1.00 12.33 O ATOM 267 CB THR A 34 16.326 32.013 14.521 1.00 11.28 C ATOM 268 OG1 THR A 34 17.701 31.784 14.189 1.00 13.81 O ATOM 269 CG2 THR A 34 16.034 31.374 15.863 1.00 15.00 C ATOM 270 N LEU A 35 13.357 30.487 14.250 1.00 11.02 N ATOM 271 CA LEU A 35 11.992 30.511 14.737 1.00 11.38 C ATOM 272 C LEU A 35 11.973 30.176 16.211 1.00 14.17 C ATOM 273 O LEU A 35 12.796 29.408 16.689 1.00 13.61 O ATOM 274 CB LEU A 35 11.140 29.463 14.022 1.00 12.98 C ATOM 275 CG LEU A 35 11.052 29.443 12.501 1.00 15.31 C ATOM 276 CD1 LEU A 35 10.278 28.212 12.068 1.00 19.13 C ATOM 277 CD2 LEU A 35 10.377 30.692 11.999 1.00 14.44 C ATOM 278 N TYR A 36 10.991 30.706 16.927 1.00 11.89 N ATOM 279 CA TYR A 36 10.714 30.271 18.289 1.00 12.63 C ATOM 280 C TYR A 36 9.247 29.860 18.332 1.00 12.61 C ATOM 281 O TYR A 36 8.374 30.675 18.080 1.00 12.06 O ATOM 282 CB TYR A 36 11.023 31.383 19.289 1.00 10.68 C ATOM 283 CG TYR A 36 12.451 31.882 19.200 1.00 12.44 C ATOM 284 CD1 TYR A 36 12.837 32.763 18.205 1.00 13.27 C ATOM 285 CD2 TYR A 36 13.412 31.466 20.110 1.00 14.56 C ATOM 286 CE1 TYR A 36 14.136 33.220 18.119 1.00 13.69 C ATOM 287 CE2 TYR A 36 14.710 31.916 20.031 1.00 16.14 C ATOM 288 CZ TYR A 36 15.069 32.792 19.033 1.00 18.06 C ATOM 289 OH TYR A 36 16.363 33.240 18.952 1.00 16.60 O ATOM 290 N VAL A 37 8.989 28.587 18.624 1.00 12.00 N ATOM 291 CA VAL A 37 7.666 27.999 18.453 1.00 11.89 C ATOM 292 C VAL A 37 7.198 27.289 19.715 1.00 14.04 C ATOM 293 O VAL A 37 8.001 26.881 20.544 1.00 12.64 O ATOM 294 CB VAL A 37 7.616 26.992 17.280 1.00 12.91 C ATOM 295 CG1 VAL A 37 8.296 27.562 16.048 1.00 12.20 C ATOM 296 CG2 VAL A 37 8.242 25.669 17.686 1.00 12.27 C ATOM 297 N THR A 38 5.887 27.148 19.846 1.00 12.04 N ATOM 298 CA THR A 38 5.302 26.458 20.985 1.00 13.58 C ATOM 299 C THR A 38 4.086 25.641 20.556 1.00 11.74 C ATOM 300 O THR A 38 3.442 25.950 19.560 1.00 12.73 O ATOM 301 CB THR A 38 4.896 27.452 22.083 1.00 14.15 C ATOM 302 OG1 THR A 38 4.374 26.740 23.212 1.00 11.95 O ATOM 303 CG2 THR A 38 3.850 28.418 21.558 1.00 14.18 C ATOM 304 N ASP A 39 3.785 24.590 21.311 1.00 13.85 N ATOM 305 CA ASP A 39 2.464 23.976 21.271 1.00 13.79 C ATOM 306 C ASP A 39 1.805 24.014 22.645 1.00 15.82 C ATOM 307 O ASP A 39 0.858 23.281 22.911 1.00 17.57 O ATOM 308 CB ASP A 39 2.533 22.540 20.727 1.00 15.09 C ATOM 309 CG ASP A 39 3.260 21.587 21.658 1.00 15.44 C ATOM 310 OD1 ASP A 39 3.691 22.019 22.743 1.00 16.05 O ATOM 311 OD2 ASP A 39 3.398 20.400 21.297 1.00 15.24 O ATOM 312 N TYR A 40 2.314 24.889 23.498 1.00 15.07 N ATOM 313 CA TYR A 40 1.738 25.106 24.813 1.00 16.90 C ATOM 314 C TYR A 40 1.762 23.869 25.699 1.00 17.29 C ATOM 315 O TYR A 40 0.922 23.699 26.573 1.00 17.80 O ATOM 316 CB TYR A 40 0.340 25.702 24.686 1.00 15.30 C ATOM 317 CG TYR A 40 0.398 27.140 24.226 1.00 15.39 C ATOM 318 CD1 TYR A 40 0.575 28.169 25.136 1.00 15.70 C ATOM 319 CD2 TYR A 40 0.314 27.464 22.881 1.00 15.88 C ATOM 320 CE1 TYR A 40 0.646 29.478 24.728 1.00 17.63 C ATOM 321 CE2 TYR A 40 0.384 28.775 22.460 1.00 17.51 C ATOM 322 CZ TYR A 40 0.550 29.779 23.387 1.00 17.88 C ATOM 323 OH TYR A 40 0.622 31.087 22.981 1.00 18.24 O ATOM 324 N THR A 41 2.752 23.018 25.465 1.00 17.25 N ATOM 325 CA THR A 41 3.093 21.948 26.388 1.00 17.96 C ATOM 326 C THR A 41 4.498 22.226 26.898 1.00 18.73 C ATOM 327 O THR A 41 5.311 22.803 26.189 1.00 18.02 O ATOM 328 CB THR A 41 3.063 20.566 25.731 1.00 17.65 C ATOM 329 OG1 THR A 41 4.136 20.458 24.795 1.00 17.38 O ATOM 330 CG2 THR A 41 1.741 20.338 25.020 1.00 17.61 C ATOM 331 N GLU A 42 4.762 21.820 28.133 1.00 14.05 N ATOM 332 CA GLU A 42 5.998 22.159 28.825 1.00 18.02 C ATOM 333 C GLU A 42 7.084 21.097 28.652 1.00 17.73 C ATOM 334 O GLU A 42 6.795 19.909 28.600 1.00 15.96 O ATOM 335 CB GLU A 42 5.693 22.352 30.313 1.00 16.62 C ATOM 336 CG GLU A 42 6.726 23.124 31.091 1.00 17.28 C ATOM 337 CD GLU A 42 6.292 23.368 32.527 1.00 21.15 C ATOM 338 OE1 GLU A 42 5.176 22.956 32.891 1.00 22.63 O ATOM 339 OE2 GLU A 42 7.066 23.971 33.286 1.00 20.07 O ATOM 340 N ASN A 43 8.334 21.539 28.569 1.00 15.81 N ATOM 341 CA ASN A 43 9.469 20.633 28.455 1.00 17.32 C ATOM 342 C ASN A 43 10.601 21.106 29.355 1.00 17.19 C ATOM 343 O ASN A 43 11.070 22.229 29.225 1.00 17.00 O ATOM 344 CB ASN A 43 9.945 20.530 27.003 1.00 16.42 C ATOM 345 CG ASN A 43 10.973 19.433 26.799 1.00 19.29 C ATOM 346 OD1 ASN A 43 11.947 19.335 27.537 1.00 18.26 O ATOM 347 ND2 ASN A 43 10.756 18.601 25.790 1.00 15.77 N ATOM 348 N GLU A 44 11.024 20.245 30.274 1.00 19.15 N ATOM 349 CA GLU A 44 12.010 20.616 31.286 1.00 22.77 C ATOM 350 C GLU A 44 13.364 21.051 30.726 1.00 19.69 C ATOM 351 O GLU A 44 14.164 21.635 31.445 1.00 21.13 O ATOM 352 CB GLU A 44 12.192 19.483 32.304 1.00 25.48 C ATOM 353 CG GLU A 44 10.925 19.131 33.063 1.00 30.55 C ATOM 354 CD GLU A 44 11.178 18.777 34.519 1.00 46.67 C ATOM 355 OE1 GLU A 44 12.233 19.167 35.063 1.00 48.16 O ATOM 356 OE2 GLU A 44 10.317 18.106 35.120 1.00 47.09 O ATOM 357 N LEU A 45 13.618 20.772 29.451 1.00 19.99 N ATOM 358 CA LEU A 45 14.889 21.128 28.836 1.00 19.66 C ATOM 359 C LEU A 45 14.754 22.379 27.979 1.00 18.31 C ATOM 360 O LEU A 45 15.702 22.796 27.322 1.00 18.73 O ATOM 361 CB LEU A 45 15.428 19.969 27.997 1.00 23.62 C ATOM 362 CG LEU A 45 15.558 18.611 28.686 1.00 24.83 C ATOM 363 CD1 LEU A 45 15.926 17.541 27.670 1.00 25.51 C ATOM 364 CD2 LEU A 45 16.580 18.667 29.801 1.00 24.82 C ATOM 365 N PHE A 46 13.569 22.977 27.988 1.00 16.22 N ATOM 366 CA PHE A 46 13.352 24.227 27.273 1.00 15.69 C ATOM 367 C PHE A 46 13.833 25.411 28.105 1.00 15.55 C ATOM 368 O PHE A 46 13.797 25.376 29.328 1.00 16.09 O ATOM 369 CB PHE A 46 11.873 24.416 26.951 1.00 15.61 C ATOM 370 CG PHE A 46 11.379 23.562 25.820 1.00 16.74 C ATOM 371 CD1 PHE A 46 12.222 22.681 25.180 1.00 17.38 C ATOM 372 CD2 PHE A 46 10.064 23.643 25.401 1.00 17.06 C ATOM 373 CE1 PHE A 46 11.763 21.899 24.142 1.00 16.66 C ATOM 374 CE2 PHE A 46 9.603 22.863 24.369 1.00 15.85 C ATOM 375 CZ PHE A 46 10.454 21.990 23.739 1.00 16.49 C ATOM 376 N PHE A 47 14.280 26.457 27.423 1.00 15.39 N ATOM 377 CA PHE A 47 14.595 27.726 28.052 1.00 17.75 C ATOM 378 C PHE A 47 13.403 28.285 28.817 1.00 14.99 C ATOM 379 O PHE A 47 12.312 28.408 28.269 1.00 16.64 O ATOM 380 CB PHE A 47 15.055 28.736 27.005 1.00 19.64 C ATOM 381 CG PHE A 47 15.463 30.052 27.583 1.00 19.02 C ATOM 382 CD1 PHE A 47 14.616 31.144 27.520 1.00 21.40 C ATOM 383 CD2 PHE A 47 16.685 30.197 28.201 1.00 18.83 C ATOM 384 CE1 PHE A 47 14.990 32.351 28.054 1.00 18.74 C ATOM 385 CE2 PHE A 47 17.061 31.401 28.735 1.00 22.85 C ATOM 386 CZ PHE A 47 16.213 32.479 28.663 1.00 20.03 C ATOM 387 N PRO A 48 13.618 28.636 30.093 1.00 17.13 N ATOM 388 CA PRO A 48 12.633 29.411 30.848 1.00 15.59 C ATOM 389 C PRO A 48 12.592 30.861 30.383 1.00 16.64 C ATOM 390 O PRO A 48 13.466 31.651 30.725 1.00 16.51 O ATOM 391 CB PRO A 48 13.154 29.329 32.281 1.00 16.62 C ATOM 392 CG PRO A 48 14.621 29.176 32.126 1.00 18.12 C ATOM 393 CD PRO A 48 14.829 28.361 30.884 1.00 17.38 C ATOM 394 N MET A 49 11.571 31.200 29.609 1.00 15.47 N ATOM 395 CA MET A 49 11.396 32.564 29.140 1.00 15.84 C ATOM 396 C MET A 49 10.902 33.469 30.263 1.00 13.64 C ATOM 397 O MET A 49 9.892 33.183 30.895 1.00 13.45 O ATOM 398 CB MET A 49 10.417 32.598 27.974 1.00 15.96 C ATOM 399 CG MET A 49 10.446 33.882 27.200 1.00 19.62 C ATOM 400 SD MET A 49 12.005 34.119 26.346 1.00 25.97 S ATOM 401 CE MET A 49 11.517 35.327 25.119 1.00 20.55 C ATOM 402 N SER A 50 11.622 34.559 30.502 1.00 13.28 N ATOM 403 CA SER A 50 11.271 35.492 31.569 1.00 13.91 C ATOM 404 C SER A 50 10.120 36.405 31.163 1.00 16.00 C ATOM 405 O SER A 50 10.153 37.008 30.100 1.00 14.31 O ATOM 406 CB SER A 50 12.483 36.329 31.974 1.00 15.56 C ATOM 407 OG SER A 50 12.133 37.294 32.945 1.00 14.67 O ATOM 408 N PRO A 51 9.148 36.542 32.053 1.00 15.74 N ATOM 409 CA PRO A 51 8.078 37.525 31.882 1.00 14.97 C ATOM 410 C PRO A 51 8.599 38.934 32.137 1.00 14.21 C ATOM 411 O PRO A 51 7.903 39.899 31.856 1.00 16.82 O ATOM 412 CB PRO A 51 7.070 37.152 32.980 1.00 14.59 C ATOM 413 CG PRO A 51 7.491 35.825 33.495 1.00 13.25 C ATOM 414 CD PRO A 51 8.948 35.707 33.246 1.00 14.25 C ATOM 415 N TYR A 52 9.810 39.041 32.672 1.00 12.47 N ATOM 416 CA TYR A 52 10.306 40.310 33.180 1.00 17.61 C ATOM 417 C TYR A 52 11.266 40.953 32.186 1.00 17.29 C ATOM 418 O TYR A 52 11.237 42.163 31.971 1.00 22.86 O ATOM 419 CB TYR A 52 10.967 40.117 34.547 1.00 16.97 C ATOM 420 CG TYR A 52 10.224 39.140 35.432 1.00 14.68 C ATOM 421 CD1 TYR A 52 8.871 39.303 35.692 1.00 14.44 C ATOM 422 CD2 TYR A 52 10.867 38.045 35.986 1.00 12.68 C ATOM 423 CE1 TYR A 52 8.182 38.408 36.488 1.00 12.97 C ATOM 424 CE2 TYR A 52 10.187 37.146 36.784 1.00 17.36 C ATOM 425 CZ TYR A 52 8.846 37.331 37.032 1.00 14.16 C ATOM 426 OH TYR A 52 8.171 36.437 37.825 1.00 15.17 O ATOM 427 N THR A 53 12.111 40.133 31.573 1.00 17.55 N ATOM 428 CA THR A 53 13.245 40.642 30.816 1.00 20.27 C ATOM 429 C THR A 53 13.058 40.457 29.313 1.00 20.34 C ATOM 430 O THR A 53 13.779 41.049 28.513 1.00 19.88 O ATOM 431 CB THR A 53 14.541 39.954 31.246 1.00 23.25 C ATOM 432 OG1 THR A 53 14.421 38.546 31.024 1.00 16.26 O ATOM 433 CG2 THR A 53 14.811 40.215 32.724 1.00 23.36 C ATOM 434 N SER A 54 12.030 39.681 28.976 1.00 17.28 N ATOM 435 CA SER A 54 11.617 39.414 27.604 1.00 17.94 C ATOM 436 C SER A 54 11.092 40.659 26.908 1.00 18.91 C ATOM 437 O SER A 54 10.478 41.520 27.530 1.00 18.47 O ATOM 438 CB SER A 54 10.521 38.347 27.586 1.00 18.68 C ATOM 439 OG SER A 54 11.059 37.058 27.796 1.00 24.41 O ATOM 440 N SER A 55 11.326 40.731 25.602 1.00 16.42 N ATOM 441 CA SER A 55 10.840 41.838 24.797 1.00 18.16 C ATOM 442 C SER A 55 9.321 41.950 24.883 1.00 17.85 C ATOM 443 O SER A 55 8.614 40.948 24.926 1.00 15.36 O ATOM 444 CB SER A 55 11.264 41.654 23.343 1.00 18.77 C ATOM 445 OG SER A 55 10.747 42.691 22.538 1.00 21.05 O ATOM 446 N SER A 56 8.822 43.178 24.904 1.00 18.82 N ATOM 447 CA SER A 56 7.386 43.406 25.035 1.00 17.38 C ATOM 448 C SER A 56 6.590 42.840 23.859 1.00 19.31 C ATOM 449 O SER A 56 5.379 42.686 23.934 1.00 17.70 O ATOM 450 CB SER A 56 7.104 44.901 25.172 1.00 21.48 C ATOM 451 OG SER A 56 7.415 45.580 23.968 1.00 24.55 O ATOM 452 N ARG A 57 7.321 42.556 22.789 1.00 20.54 N ATOM 453 CA ARG A 57 6.783 42.037 21.545 1.00 20.36 C ATOM 454 C ARG A 57 6.371 40.577 21.674 1.00 21.95 C ATOM 455 O ARG A 57 5.459 40.114 20.999 1.00 23.07 O ATOM 456 CB ARG A 57 7.859 42.153 20.469 1.00 27.93 C ATOM 457 CG ARG A 57 7.332 42.344 19.081 1.00 29.04 C ATOM 458 CD ARG A 57 8.382 41.997 18.060 1.00 27.97 C ATOM 459 NE ARG A 57 7.774 41.455 16.858 1.00 28.57 N ATOM 460 CZ ARG A 57 7.527 42.164 15.768 1.00 27.39 C ATOM 461 NH1 ARG A 57 7.854 43.448 15.726 1.00 23.48 N ATOM 462 NH2 ARG A 57 6.963 41.586 14.721 1.00 27.11 N ATOM 463 N TRP A 58 7.072 39.851 22.533 1.00 18.43 N ATOM 464 CA TRP A 58 6.827 38.431 22.719 1.00 18.83 C ATOM 465 C TRP A 58 5.359 38.166 23.037 1.00 21.10 C ATOM 466 O TRP A 58 4.876 38.554 24.094 1.00 21.28 O ATOM 467 CB TRP A 58 7.722 37.903 23.844 1.00 18.64 C ATOM 468 CG TRP A 58 7.566 36.447 24.142 1.00 15.98 C ATOM 469 CD1 TRP A 58 6.900 35.892 25.193 1.00 18.20 C ATOM 470 CD2 TRP A 58 8.105 35.359 23.391 1.00 14.90 C ATOM 471 NE1 TRP A 58 6.980 34.525 25.140 1.00 16.23 N ATOM 472 CE2 TRP A 58 7.717 34.171 24.041 1.00 16.97 C ATOM 473 CE3 TRP A 58 8.873 35.271 22.229 1.00 16.78 C ATOM 474 CZ2 TRP A 58 8.073 32.914 23.568 1.00 15.75 C ATOM 475 CZ3 TRP A 58 9.223 34.025 21.763 1.00 17.07 C ATOM 476 CH2 TRP A 58 8.824 32.862 22.430 1.00 16.71 C ATOM 477 N ARG A 59 4.651 37.506 22.124 1.00 19.37 N ATOM 478 CA ARG A 59 3.263 37.133 22.396 1.00 25.03 C ATOM 479 C ARG A 59 3.120 35.678 22.811 1.00 21.92 C ATOM 480 O ARG A 59 2.034 35.119 22.740 1.00 21.21 O ATOM 481 CB ARG A 59 2.361 37.384 21.188 1.00 25.11 C ATOM 482 CG ARG A 59 3.020 38.102 20.053 1.00 31.31 C ATOM 483 CD ARG A 59 3.126 39.575 20.335 1.00 34.12 C ATOM 484 NE ARG A 59 3.997 40.234 19.369 1.00 35.42 N ATOM 485 CZ ARG A 59 3.879 41.503 19.008 1.00 32.43 C ATOM 486 NH1 ARG A 59 4.712 42.018 18.120 1.00 35.52 N ATOM 487 NH2 ARG A 59 2.931 42.257 19.541 1.00 40.00 N ATOM 488 N GLY A 60 4.214 35.070 23.243 1.00 17.28 N ATOM 489 CA GLY A 60 4.195 33.667 23.605 1.00 12.44 C ATOM 490 C GLY A 60 4.079 33.432 25.092 1.00 15.73 C ATOM 491 O GLY A 60 3.967 34.372 25.876 1.00 16.77 O ATOM 492 N PRO A 61 4.108 32.164 25.479 1.00 15.87 N ATOM 493 CA PRO A 61 4.047 31.794 26.889 1.00 14.45 C ATOM 494 C PRO A 61 5.383 32.017 27.568 1.00 15.03 C ATOM 495 O PRO A 61 6.384 32.282 26.922 1.00 14.37 O ATOM 496 CB PRO A 61 3.759 30.300 26.832 1.00 17.13 C ATOM 497 CG PRO A 61 4.460 29.848 25.587 1.00 16.51 C ATOM 498 CD PRO A 61 4.465 31.015 24.629 1.00 14.41 C ATOM 499 N PHE A 62 5.375 31.925 28.892 1.00 16.06 N ATOM 500 CA PHE A 62 6.574 32.100 29.695 1.00 12.25 C ATOM 501 C PHE A 62 6.964 30.776 30.352 1.00 11.39 C ATOM 502 O PHE A 62 6.171 29.848 30.393 1.00 13.75 O ATOM 503 CB PHE A 62 6.356 33.206 30.728 1.00 13.25 C ATOM 504 CG PHE A 62 6.144 34.560 30.113 1.00 15.04 C ATOM 505 CD1 PHE A 62 7.125 35.139 29.331 1.00 15.44 C ATOM 506 CD2 PHE A 62 4.959 35.244 30.297 1.00 15.26 C ATOM 507 CE1 PHE A 62 6.932 36.377 28.758 1.00 16.03 C ATOM 508 CE2 PHE A 62 4.764 36.480 29.721 1.00 16.21 C ATOM 509 CZ PHE A 62 5.751 37.045 28.955 1.00 13.62 C ATOM 510 N GLY A 63 8.193 30.688 30.844 1.00 13.57 N ATOM 511 CA GLY A 63 8.694 29.432 31.366 1.00 14.88 C ATOM 512 C GLY A 63 9.186 28.518 30.253 1.00 14.36 C ATOM 513 O GLY A 63 9.511 28.977 29.165 1.00 14.22 O ATOM 514 N ARG A 64 9.232 27.218 30.528 1.00 15.49 N ATOM 515 CA ARG A 64 9.815 26.243 29.610 1.00 14.86 C ATOM 516 C ARG A 64 8.802 25.715 28.602 1.00 14.86 C ATOM 517 O ARG A 64 8.430 24.550 28.655 1.00 13.47 O ATOM 518 CB ARG A 64 10.398 25.075 30.403 1.00 13.68 C ATOM 519 CG ARG A 64 11.383 25.482 31.482 1.00 16.52 C ATOM 520 CD ARG A 64 12.100 24.267 32.037 1.00 15.50 C ATOM 521 NE ARG A 64 12.957 24.585 33.171 1.00 15.41 N ATOM 522 CZ ARG A 64 14.283 24.653 33.112 1.00 17.36 C ATOM 523 NH1 ARG A 64 14.912 24.434 31.966 1.00 22.00 N ATOM 524 NH2 ARG A 64 14.982 24.942 34.199 1.00 17.39 N ATOM 525 N PHE A 65 8.379 26.574 27.679 1.00 13.59 N ATOM 526 CA PHE A 65 7.216 26.298 26.844 1.00 14.02 C ATOM 527 C PHE A 65 7.513 26.488 25.358 1.00 13.23 C ATOM 528 O PHE A 65 6.693 26.148 24.509 1.00 15.54 O ATOM 529 CB PHE A 65 6.047 27.193 27.248 1.00 13.08 C ATOM 530 CG PHE A 65 5.261 26.677 28.416 1.00 13.67 C ATOM 531 CD1 PHE A 65 5.581 27.062 29.706 1.00 16.63 C ATOM 532 CD2 PHE A 65 4.199 25.814 28.226 1.00 15.93 C ATOM 533 CE1 PHE A 65 4.861 26.592 30.784 1.00 17.40 C ATOM 534 CE2 PHE A 65 3.475 25.341 29.299 1.00 19.06 C ATOM 535 CZ PHE A 65 3.807 25.733 30.582 1.00 20.36 C ATOM 536 N SER A 66 8.681 27.039 25.050 1.00 12.49 N ATOM 537 CA SER A 66 9.019 27.378 23.673 1.00 13.55 C ATOM 538 C SER A 66 10.424 26.903 23.297 1.00 15.99 C ATOM 539 O SER A 66 11.288 26.755 24.156 1.00 14.82 O ATOM 540 CB SER A 66 8.885 28.885 23.441 1.00 13.65 C ATOM 541 OG SER A 66 7.537 29.298 23.530 1.00 14.07 O ATOM 542 N ILE A 67 10.638 26.661 22.008 1.00 12.03 N ATOM 543 CA ILE A 67 11.910 26.132 21.538 1.00 10.38 C ATOM 544 C ILE A 67 12.413 26.867 20.295 1.00 11.54 C ATOM 545 O ILE A 67 11.636 27.250 19.423 1.00 13.74 O ATOM 546 CB ILE A 67 11.846 24.602 21.276 1.00 14.51 C ATOM 547 CG1 ILE A 67 13.221 24.071 20.859 1.00 13.82 C ATOM 548 CG2 ILE A 67 10.785 24.271 20.238 1.00 15.18 C ATOM 549 CD1 ILE A 67 13.318 22.566 20.808 1.00 17.95 C ATOM 550 N ARG A 68 13.724 27.069 20.240 1.00 11.13 N ATOM 551 CA ARG A 68 14.373 27.668 19.087 1.00 10.95 C ATOM 552 C ARG A 68 14.532 26.642 17.974 1.00 13.71 C ATOM 553 O ARG A 68 15.039 25.545 18.196 1.00 13.76 O ATOM 554 CB ARG A 68 15.742 28.226 19.487 1.00 14.32 C ATOM 555 CG ARG A 68 16.388 29.131 18.456 1.00 13.36 C ATOM 556 CD ARG A 68 17.635 29.784 19.020 1.00 20.84 C ATOM 557 NE ARG A 68 18.370 28.856 19.867 1.00 31.12 N ATOM 558 CZ ARG A 68 18.932 29.174 21.026 1.00 26.67 C ATOM 559 NH1 ARG A 68 18.860 30.412 21.493 1.00 24.31 N ATOM 560 NH2 ARG A 68 19.579 28.250 21.715 1.00 29.65 N ATOM 561 N CYS A 69 14.098 27.009 16.776 1.00 13.67 N ATOM 562 CA CYS A 69 14.423 26.255 15.577 1.00 10.71 C ATOM 563 C CYS A 69 15.324 27.061 14.645 1.00 12.45 C ATOM 564 O CYS A 69 14.992 28.175 14.259 1.00 13.03 O ATOM 565 CB CYS A 69 13.145 25.849 14.845 1.00 13.23 C ATOM 566 SG CYS A 69 11.875 25.141 15.910 1.00 15.64 S ATOM 567 N ILE A 70 16.476 26.498 14.306 1.00 12.54 N ATOM 568 CA ILE A 70 17.411 27.165 13.415 1.00 12.22 C ATOM 569 C ILE A 70 17.366 26.531 12.031 1.00 13.49 C ATOM 570 O ILE A 70 17.583 25.336 11.885 1.00 12.57 O ATOM 571 CB ILE A 70 18.845 27.119 13.958 1.00 14.57 C ATOM 572 CG1 ILE A 70 18.884 27.653 15.392 1.00 18.60 C ATOM 573 CG2 ILE A 70 19.779 27.916 13.063 1.00 17.58 C ATOM 574 CD1 ILE A 70 20.271 27.775 15.963 1.00 22.00 C ATOM 575 N LEU A 71 17.076 27.350 11.025 1.00 12.87 N ATOM 576 CA LEU A 71 16.929 26.883 9.653 1.00 12.71 C ATOM 577 C LEU A 71 18.098 27.344 8.793 1.00 14.10 C ATOM 578 O LEU A 71 18.359 28.537 8.687 1.00 11.51 O ATOM 579 CB LEU A 71 15.618 27.396 9.058 1.00 13.04 C ATOM 580 CG LEU A 71 14.324 26.693 9.469 1.00 12.51 C ATOM 581 CD1 LEU A 71 14.211 26.624 10.980 1.00 11.94 C ATOM 582 CD2 LEU A 71 13.118 27.400 8.875 1.00 14.13 C ATOM 583 N TRP A 72 18.789 26.386 8.183 1.00 12.37 N ATOM 584 CA TRP A 72 19.937 26.667 7.342 1.00 16.23 C ATOM 585 C TRP A 72 19.629 26.436 5.872 1.00 15.90 C ATOM 586 O TRP A 72 18.751 25.653 5.522 1.00 15.28 O ATOM 587 CB TRP A 72 21.112 25.767 7.727 1.00 16.83 C ATOM 588 CG TRP A 72 21.637 25.966 9.100 1.00 17.68 C ATOM 589 CD1 TRP A 72 21.378 25.196 10.192 1.00 20.11 C ATOM 590 CD2 TRP A 72 22.535 26.992 9.536 1.00 20.99 C ATOM 591 NE1 TRP A 72 22.049 25.680 11.282 1.00 21.83 N ATOM 592 CE2 TRP A 72 22.771 26.782 10.907 1.00 22.57 C ATOM 593 CE3 TRP A 72 23.163 28.067 8.899 1.00 19.70 C ATOM 594 CZ2 TRP A 72 23.602 27.608 11.654 1.00 25.55 C ATOM 595 CZ3 TRP A 72 23.988 28.883 9.643 1.00 24.37 C ATOM 596 CH2 TRP A 72 24.199 28.651 11.006 1.00 26.41 C ATOM 597 N ASP A 73 20.385 27.112 5.017 1.00 16.64 N ATOM 598 CA ASP A 73 20.390 26.810 3.599 1.00 13.57 C ATOM 599 C ASP A 73 19.004 26.821 2.965 1.00 16.14 C ATOM 600 O ASP A 73 18.299 27.816 3.032 1.00 13.84 O ATOM 601 CB ASP A 73 21.082 25.468 3.376 1.00 16.42 C ATOM 602 CG ASP A 73 22.498 25.461 3.909 1.00 19.90 C ATOM 603 OD1 ASP A 73 23.143 26.523 3.849 1.00 22.12 O ATOM 604 OD2 ASP A 73 22.962 24.411 4.398 1.00 21.52 O ATOM 605 N GLU A 74 18.622 25.713 2.345 1.00 13.69 N ATOM 606 CA GLU A 74 17.374 25.674 1.587 1.00 13.24 C ATOM 607 C GLU A 74 16.165 26.010 2.460 1.00 16.58 C ATOM 608 O GLU A 74 15.163 26.524 1.974 1.00 12.21 O ATOM 609 CB GLU A 74 17.181 24.310 0.917 1.00 16.02 C ATOM 610 CG GLU A 74 17.015 23.152 1.877 1.00 16.71 C ATOM 611 CD GLU A 74 18.315 22.417 2.136 1.00 18.29 C ATOM 612 OE1 GLU A 74 19.382 23.057 2.084 1.00 19.18 O ATOM 613 OE2 GLU A 74 18.265 21.199 2.396 1.00 17.68 O ATOM 614 N HIS A 75 16.270 25.711 3.750 1.00 13.95 N ATOM 615 CA HIS A 75 15.178 25.961 4.682 1.00 14.29 C ATOM 616 C HIS A 75 15.090 27.443 5.036 1.00 12.51 C ATOM 617 O HIS A 75 14.003 28.010 5.130 1.00 14.06 O ATOM 618 CB HIS A 75 15.359 25.130 5.955 1.00 13.29 C ATOM 619 CG HIS A 75 15.789 23.718 5.706 1.00 14.98 C ATOM 620 ND1 HIS A 75 14.922 22.743 5.265 1.00 15.74 N ATOM 621 CD2 HIS A 75 16.991 23.114 5.848 1.00 14.74 C ATOM 622 CE1 HIS A 75 15.572 21.602 5.138 1.00 18.07 C ATOM 623 NE2 HIS A 75 16.829 21.799 5.487 1.00 15.09 N ATOM 624 N ASP A 76 16.251 28.053 5.242 1.00 12.89 N ATOM 625 CA ASP A 76 16.401 29.506 5.283 1.00 12.19 C ATOM 626 C ASP A 76 15.741 30.175 4.085 1.00 12.69 C ATOM 627 O ASP A 76 14.822 30.974 4.231 1.00 12.36 O ATOM 628 CB ASP A 76 17.892 29.854 5.306 1.00 16.19 C ATOM 629 CG ASP A 76 18.155 31.321 5.577 1.00 14.38 C ATOM 630 OD1 ASP A 76 17.214 32.135 5.491 1.00 13.35 O ATOM 631 OD2 ASP A 76 19.319 31.654 5.871 1.00 14.89 O ATOM 632 N PHE A 77 16.236 29.843 2.899 1.00 13.61 N ATOM 633 CA PHE A 77 15.759 30.441 1.664 1.00 15.22 C ATOM 634 C PHE A 77 14.249 30.307 1.516 1.00 12.16 C ATOM 635 O PHE A 77 13.572 31.256 1.134 1.00 15.11 O ATOM 636 CB PHE A 77 16.470 29.806 0.471 1.00 15.98 C ATOM 637 CG PHE A 77 17.910 30.207 0.341 1.00 18.29 C ATOM 638 CD1 PHE A 77 18.265 31.539 0.233 1.00 20.12 C ATOM 639 CD2 PHE A 77 18.909 29.254 0.326 1.00 19.91 C ATOM 640 CE1 PHE A 77 19.584 31.907 0.113 1.00 20.03 C ATOM 641 CE2 PHE A 77 20.230 29.620 0.205 1.00 22.37 C ATOM 642 CZ PHE A 77 20.567 30.947 0.099 1.00 19.13 C ATOM 643 N TYR A 78 13.729 29.129 1.825 1.00 11.75 N ATOM 644 CA TYR A 78 12.305 28.875 1.699 1.00 12.94 C ATOM 645 C TYR A 78 11.476 29.749 2.635 1.00 14.41 C ATOM 646 O TYR A 78 10.561 30.436 2.203 1.00 13.65 O ATOM 647 CB TYR A 78 12.002 27.403 1.974 1.00 10.65 C ATOM 648 CG TYR A 78 10.551 27.035 1.772 1.00 10.81 C ATOM 649 CD1 TYR A 78 9.832 27.542 0.703 1.00 14.93 C ATOM 650 CD2 TYR A 78 9.902 26.178 2.647 1.00 13.71 C ATOM 651 CE1 TYR A 78 8.511 27.211 0.512 1.00 16.19 C ATOM 652 CE2 TYR A 78 8.579 25.843 2.465 1.00 16.70 C ATOM 653 CZ TYR A 78 7.886 26.363 1.396 1.00 15.25 C ATOM 654 OH TYR A 78 6.569 26.035 1.201 1.00 16.41 O ATOM 655 N CYS A 79 11.809 29.707 3.921 1.00 11.45 N ATOM 656 CA CYS A 79 10.954 30.247 4.970 1.00 11.43 C ATOM 657 C CYS A 79 11.157 31.715 5.342 1.00 13.81 C ATOM 658 O CYS A 79 10.234 32.353 5.832 1.00 13.97 O ATOM 659 CB CYS A 79 11.103 29.411 6.242 1.00 15.29 C ATOM 660 SG CYS A 79 10.565 27.700 6.107 1.00 14.85 S ATOM 661 N ARG A 80 12.361 32.236 5.146 1.00 14.33 N ATOM 662 CA ARG A 80 12.731 33.512 5.755 1.00 14.85 C ATOM 663 C ARG A 80 11.794 34.682 5.435 1.00 16.25 C ATOM 664 O ARG A 80 11.594 35.567 6.259 1.00 16.33 O ATOM 665 CB ARG A 80 14.204 33.852 5.498 1.00 16.07 C ATOM 666 CG ARG A 80 14.446 34.817 4.372 1.00 20.43 C ATOM 667 CD ARG A 80 14.486 34.082 3.058 1.00 18.18 C ATOM 668 NE ARG A 80 15.390 34.710 2.107 1.00 16.81 N ATOM 669 CZ ARG A 80 16.707 34.548 2.106 1.00 18.71 C ATOM 670 NH1 ARG A 80 17.288 33.787 3.016 1.00 20.13 N ATOM 671 NH2 ARG A 80 17.445 35.160 1.194 1.00 18.30 N ATOM 672 N ASN A 81 11.213 34.671 4.245 1.00 17.61 N ATOM 673 CA ASN A 81 10.243 35.690 3.865 1.00 17.48 C ATOM 674 C ASN A 81 8.839 35.129 3.662 1.00 17.29 C ATOM 675 O ASN A 81 8.074 35.625 2.844 1.00 17.04 O ATOM 676 CB ASN A 81 10.714 36.437 2.615 1.00 19.65 C ATOM 677 CG ASN A 81 11.884 37.361 2.898 1.00 27.85 C ATOM 678 OD1 ASN A 81 13.007 37.107 2.470 1.00 26.52 O ATOM 679 ND2 ASN A 81 11.624 38.436 3.627 1.00 23.99 N ATOM 680 N TYR A 82 8.506 34.099 4.429 1.00 17.88 N ATOM 681 CA TYR A 82 7.325 33.291 4.166 1.00 14.90 C ATOM 682 C TYR A 82 6.626 32.907 5.466 1.00 17.17 C ATOM 683 O TYR A 82 5.452 33.199 5.652 1.00 18.30 O ATOM 684 CB TYR A 82 7.704 32.041 3.374 1.00 14.63 C ATOM 685 CG TYR A 82 6.572 31.057 3.171 1.00 16.64 C ATOM 686 CD1 TYR A 82 5.318 31.484 2.760 1.00 17.78 C ATOM 687 CD2 TYR A 82 6.763 29.698 3.384 1.00 18.17 C ATOM 688 CE1 TYR A 82 4.288 30.585 2.569 1.00 18.64 C ATOM 689 CE2 TYR A 82 5.739 28.795 3.197 1.00 18.58 C ATOM 690 CZ TYR A 82 4.504 29.242 2.788 1.00 19.42 C ATOM 691 OH TYR A 82 3.482 28.344 2.599 1.00 21.74 O ATOM 692 N ILE A 83 7.367 32.297 6.379 1.00 16.79 N ATOM 693 CA ILE A 83 6.818 31.900 7.661 1.00 16.50 C ATOM 694 C ILE A 83 6.766 33.128 8.575 1.00 19.22 C ATOM 695 O ILE A 83 7.765 33.712 8.857 1.00 18.86 O ATOM 696 CB ILE A 83 7.662 30.776 8.357 1.00 16.43 C ATOM 697 CG1 ILE A 83 7.646 29.491 7.526 1.00 20.09 C ATOM 698 CG2 ILE A 83 7.145 30.458 9.696 1.00 20.07 C ATOM 699 CD1 ILE A 83 6.373 29.193 6.969 1.00 21.67 C ATOM 700 N LYS A 84 5.567 33.499 9.001 1.00 18.66 N ATOM 701 CA LYS A 84 5.341 34.701 9.791 1.00 17.03 C ATOM 702 C LYS A 84 5.012 34.455 11.258 1.00 14.64 C ATOM 703 O LYS A 84 4.414 33.475 11.599 1.00 14.61 O ATOM 704 CB LYS A 84 4.195 35.516 9.193 1.00 18.61 C ATOM 705 CG LYS A 84 4.371 35.976 7.757 1.00 24.99 C ATOM 706 CD LYS A 84 5.717 36.571 7.581 1.00 26.54 C ATOM 707 CE LYS A 84 5.853 37.410 6.307 1.00 33.24 C ATOM 708 NZ LYS A 84 7.254 37.748 6.111 1.00 28.21 N ATOM 709 N GLU A 85 5.385 35.393 12.111 1.00 14.19 N ATOM 710 CA GLU A 85 4.989 35.308 13.507 1.00 13.50 C ATOM 711 C GLU A 85 3.481 35.127 13.610 1.00 16.07 C ATOM 712 O GLU A 85 2.717 35.874 13.006 1.00 18.32 O ATOM 713 CB GLU A 85 5.447 36.548 14.283 1.00 13.58 C ATOM 714 CG GLU A 85 6.935 36.565 14.563 1.00 13.42 C ATOM 715 CD GLU A 85 7.394 37.800 15.315 1.00 18.44 C ATOM 716 OE1 GLU A 85 6.586 38.731 15.490 1.00 15.96 O ATOM 717 OE2 GLU A 85 8.570 37.832 15.725 1.00 17.17 O ATOM 718 N GLY A 86 3.064 34.115 14.359 1.00 13.80 N ATOM 719 CA GLY A 86 1.653 33.829 14.530 1.00 14.84 C ATOM 720 C GLY A 86 1.189 32.646 13.702 1.00 16.96 C ATOM 721 O GLY A 86 0.163 32.037 13.995 1.00 16.49 O ATOM 722 N ASP A 87 1.953 32.325 12.664 1.00 16.30 N ATOM 723 CA ASP A 87 1.624 31.214 11.786 1.00 16.21 C ATOM 724 C ASP A 87 1.629 29.886 12.536 1.00 17.49 C ATOM 725 O ASP A 87 2.252 29.759 13.584 1.00 16.29 O ATOM 726 CB ASP A 87 2.602 31.153 10.615 1.00 16.23 C ATOM 727 CG ASP A 87 2.390 32.276 9.625 1.00 19.87 C ATOM 728 OD1 ASP A 87 1.387 33.003 9.765 1.00 17.35 O ATOM 729 OD2 ASP A 87 3.221 32.424 8.707 1.00 20.97 O ATOM 730 N TYR A 88 0.930 28.904 11.976 1.00 13.91 N ATOM 731 CA TYR A 88 1.100 27.511 12.363 1.00 15.56 C ATOM 732 C TYR A 88 1.956 26.745 11.357 1.00 17.04 C ATOM 733 O TYR A 88 1.829 26.927 10.149 1.00 15.26 O ATOM 734 CB TYR A 88 -0.260 26.833 12.515 1.00 16.16 C ATOM 735 CG TYR A 88 -1.146 27.479 13.555 1.00 16.44 C ATOM 736 CD1 TYR A 88 -2.031 28.485 13.209 1.00 19.88 C ATOM 737 CD2 TYR A 88 -1.092 27.085 14.881 1.00 17.87 C ATOM 738 CE1 TYR A 88 -2.835 29.080 14.153 1.00 19.31 C ATOM 739 CE2 TYR A 88 -1.894 27.668 15.828 1.00 17.92 C ATOM 740 CZ TYR A 88 -2.765 28.667 15.461 1.00 18.32 C ATOM 741 OH TYR A 88 -3.567 29.256 16.405 1.00 19.60 O ATOM 742 N VAL A 89 2.830 25.887 11.872 1.00 13.05 N ATOM 743 CA VAL A 89 3.688 25.066 11.029 1.00 14.73 C ATOM 744 C VAL A 89 3.629 23.602 11.452 1.00 12.76 C ATOM 745 O VAL A 89 3.392 23.289 12.614 1.00 15.78 O ATOM 746 CB VAL A 89 5.142 25.555 11.069 1.00 15.28 C ATOM 747 CG1 VAL A 89 5.247 26.938 10.449 1.00 14.74 C ATOM 748 CG2 VAL A 89 5.658 25.566 12.495 1.00 13.56 C ATOM 749 N VAL A 90 3.838 22.709 10.494 1.00 13.86 N ATOM 750 CA VAL A 90 4.216 21.339 10.799 1.00 14.98 C ATOM 751 C VAL A 90 5.670 21.094 10.413 1.00 14.02 C ATOM 752 O VAL A 90 6.080 21.371 9.287 1.00 15.46 O ATOM 753 CB VAL A 90 3.293 20.322 10.087 1.00 18.59 C ATOM 754 CG1 VAL A 90 3.354 20.501 8.585 1.00 18.31 C ATOM 755 CG2 VAL A 90 3.661 18.902 10.474 1.00 16.73 C ATOM 756 N MET A 91 6.446 20.568 11.353 1.00 15.33 N ATOM 757 CA MET A 91 7.855 20.292 11.118 1.00 14.30 C ATOM 758 C MET A 91 8.118 18.799 11.273 1.00 16.70 C ATOM 759 O MET A 91 7.691 18.187 12.242 1.00 16.12 O ATOM 760 CB MET A 91 8.724 21.122 12.068 1.00 19.73 C ATOM 761 CG MET A 91 8.269 22.580 12.168 1.00 19.63 C ATOM 762 SD MET A 91 9.299 23.653 13.194 1.00 25.69 S ATOM 763 CE MET A 91 10.924 23.177 12.641 1.00 16.52 C ATOM 764 N LYS A 92 8.810 18.217 10.300 1.00 16.42 N ATOM 765 CA LYS A 92 8.990 16.773 10.247 1.00 17.93 C ATOM 766 C LYS A 92 10.463 16.394 10.190 1.00 18.10 C ATOM 767 O LYS A 92 11.223 16.937 9.392 1.00 15.04 O ATOM 768 CB LYS A 92 8.224 16.174 9.064 1.00 18.88 C ATOM 769 CG LYS A 92 6.713 16.218 9.238 1.00 17.31 C ATOM 770 CD LYS A 92 5.989 15.642 8.038 1.00 19.89 C ATOM 771 CE LYS A 92 4.812 16.521 7.637 1.00 25.57 C ATOM 772 NZ LYS A 92 3.889 15.858 6.678 1.00 29.99 N ATOM 773 N ASN A 93 10.836 15.434 11.032 1.00 14.32 N ATOM 774 CA ASN A 93 12.157 14.815 11.021 1.00 16.93 C ATOM 775 C ASN A 93 13.311 15.768 11.298 1.00 16.97 C ATOM 776 O ASN A 93 14.422 15.568 10.822 1.00 17.62 O ATOM 777 CB ASN A 93 12.381 14.063 9.708 1.00 17.47 C ATOM 778 CG ASN A 93 11.453 12.877 9.555 1.00 18.13 C ATOM 779 OD1 ASN A 93 11.158 12.181 10.522 1.00 20.03 O ATOM 780 ND2 ASN A 93 10.980 12.646 8.337 1.00 20.28 N ATOM 781 N VAL A 94 13.036 16.802 12.080 1.00 15.91 N ATOM 782 CA VAL A 94 14.044 17.793 12.408 1.00 16.04 C ATOM 783 C VAL A 94 14.995 17.266 13.478 1.00 14.96 C ATOM 784 O VAL A 94 14.592 16.507 14.353 1.00 16.46 O ATOM 785 CB VAL A 94 13.399 19.109 12.870 1.00 15.54 C ATOM 786 CG1 VAL A 94 12.446 19.616 11.801 1.00 22.49 C ATOM 787 CG2 VAL A 94 12.667 18.905 14.179 1.00 16.36 C ATOM 788 N ARG A 95 16.256 17.669 13.389 1.00 12.86 N ATOM 789 CA ARG A 95 17.260 17.274 14.354 1.00 14.90 C ATOM 790 C ARG A 95 17.173 18.118 15.629 1.00 13.63 C ATOM 791 O ARG A 95 16.971 19.298 15.565 1.00 14.84 O ATOM 792 CB ARG A 95 18.659 17.402 13.737 1.00 17.30 C ATOM 793 CG ARG A 95 19.812 17.527 14.656 1.00 18.02 C ATOM 794 CD ARG A 95 21.115 17.766 13.882 1.00 21.18 C ATOM 795 NE ARG A 95 21.474 16.599 13.082 1.00 19.90 N ATOM 796 CZ ARG A 95 22.488 16.519 12.241 1.00 23.75 C ATOM 797 NH1 ARG A 95 23.257 17.541 12.044 1.00 23.31 N ATOM 798 NH2 ARG A 95 22.719 15.411 11.571 1.00 20.25 N ATOM 799 N THR A 96 17.369 17.480 16.773 1.00 16.18 N ATOM 800 CA THR A 96 17.414 18.204 18.031 1.00 16.45 C ATOM 801 C THR A 96 18.794 18.073 18.652 1.00 18.80 C ATOM 802 O THR A 96 19.477 17.076 18.463 1.00 18.47 O ATOM 803 CB THR A 96 16.373 17.682 19.021 1.00 16.33 C ATOM 804 OG1 THR A 96 16.667 16.320 19.346 1.00 17.13 O ATOM 805 CG2 THR A 96 14.977 17.775 18.418 1.00 16.63 C ATOM 806 N LYS A 97 19.197 19.102 19.382 1.00 14.67 N ATOM 807 CA LYS A 97 20.435 19.073 20.141 1.00 21.36 C ATOM 808 C LYS A 97 20.359 20.020 21.327 1.00 20.63 C ATOM 809 O LYS A 97 19.300 20.561 21.636 1.00 18.11 O ATOM 810 CB LYS A 97 21.614 19.459 19.253 1.00 21.86 C ATOM 811 CG LYS A 97 21.491 20.831 18.636 1.00 22.88 C ATOM 812 CD LYS A 97 22.616 21.100 17.658 1.00 27.61 C ATOM 813 CE LYS A 97 23.785 21.779 18.341 1.00 25.84 C ATOM 814 NZ LYS A 97 24.558 22.622 17.392 1.00 30.71 N ATOM 815 N ILE A 98 21.492 20.206 21.977 1.00 21.17 N ATOM 816 CA ILE A 98 21.656 21.145 23.074 1.00 23.27 C ATOM 817 C ILE A 98 22.495 22.374 22.711 1.00 25.91 C ATOM 818 O ILE A 98 23.529 22.265 22.092 1.00 27.74 O ATOM 819 CB ILE A 98 22.315 20.484 24.277 1.00 24.77 C ATOM 820 CG1 ILE A 98 21.447 19.388 24.858 1.00 23.37 C ATOM 821 CG2 ILE A 98 22.524 21.505 25.326 1.00 28.61 C ATOM 822 CD1 ILE A 98 20.158 19.902 25.402 1.00 24.41 C ATOM 823 N ASP A 99 22.008 23.547 23.098 1.00 23.72 N ATOM 824 CA ASP A 99 22.746 24.774 22.851 1.00 27.69 C ATOM 825 C ASP A 99 23.837 24.910 23.899 1.00 28.64 C ATOM 826 O ASP A 99 23.999 24.044 24.750 1.00 27.16 O ATOM 827 CB ASP A 99 21.822 25.997 22.826 1.00 27.51 C ATOM 828 CG ASP A 99 21.257 26.340 24.188 1.00 26.61 C ATOM 829 OD1 ASP A 99 21.740 25.793 25.194 1.00 27.21 O ATOM 830 OD2 ASP A 99 20.323 27.163 24.247 1.00 31.29 O ATOM 831 N HIS A 100 24.598 25.990 23.819 1.00 34.12 N ATOM 832 CA HIS A 100 25.745 26.179 24.694 1.00 35.58 C ATOM 833 C HIS A 100 25.388 26.279 26.177 1.00 32.85 C ATOM 834 O HIS A 100 26.267 26.258 27.031 1.00 37.11 O ATOM 835 CB HIS A 100 26.525 27.422 24.257 1.00 36.78 C ATOM 836 CG HIS A 100 27.287 27.234 22.984 1.00 34.27 C ATOM 837 ND1 HIS A 100 27.873 28.279 22.304 1.00 38.59 N ATOM 838 CD2 HIS A 100 27.567 26.118 22.271 1.00 33.89 C ATOM 839 CE1 HIS A 100 28.480 27.815 21.227 1.00 35.89 C ATOM 840 NE2 HIS A 100 28.310 26.507 21.183 1.00 33.85 N ATOM 841 N LEU A 101 24.100 26.379 26.480 1.00 33.66 N ATOM 842 CA LEU A 101 23.657 26.691 27.827 1.00 30.82 C ATOM 843 C LEU A 101 22.805 25.571 28.409 1.00 32.52 C ATOM 844 O LEU A 101 22.326 25.665 29.534 1.00 31.55 O ATOM 845 CB LEU A 101 22.879 28.004 27.833 1.00 32.08 C ATOM 846 CG LEU A 101 23.719 29.263 27.612 1.00 36.57 C ATOM 847 CD1 LEU A 101 22.848 30.501 27.657 1.00 31.77 C ATOM 848 CD2 LEU A 101 24.831 29.345 28.648 1.00 38.43 C ATOM 849 N GLY A 102 22.623 24.506 27.636 1.00 29.61 N ATOM 850 CA GLY A 102 22.040 23.285 28.157 1.00 27.60 C ATOM 851 C GLY A 102 20.601 23.072 27.730 1.00 25.06 C ATOM 852 O GLY A 102 19.964 22.112 28.152 1.00 27.60 O ATOM 853 N TYR A 103 20.089 23.977 26.901 1.00 21.81 N ATOM 854 CA TYR A 103 18.691 23.939 26.499 1.00 19.43 C ATOM 855 C TYR A 103 18.489 23.265 25.150 1.00 20.55 C ATOM 856 O TYR A 103 19.323 23.367 24.261 1.00 20.34 O ATOM 857 CB TYR A 103 18.097 25.350 26.478 1.00 20.72 C ATOM 858 CG TYR A 103 18.332 26.119 27.758 1.00 19.81 C ATOM 859 CD1 TYR A 103 17.643 25.800 28.913 1.00 21.67 C ATOM 860 CD2 TYR A 103 19.249 27.155 27.810 1.00 24.06 C ATOM 861 CE1 TYR A 103 17.857 26.494 30.086 1.00 22.63 C ATOM 862 CE2 TYR A 103 19.472 27.852 28.980 1.00 25.51 C ATOM 863 CZ TYR A 103 18.772 27.520 30.114 1.00 24.39 C ATOM 864 OH TYR A 103 18.988 28.210 31.281 1.00 27.41 O ATOM 865 N LEU A 104 17.363 22.575 25.025 1.00 16.54 N ATOM 866 CA LEU A 104 17.007 21.876 23.807 1.00 15.77 C ATOM 867 C LEU A 104 16.713 22.865 22.695 1.00 19.09 C ATOM 868 O LEU A 104 16.075 23.882 22.920 1.00 18.11 O ATOM 869 CB LEU A 104 15.761 21.026 24.046 1.00 19.29 C ATOM 870 CG LEU A 104 15.803 19.545 23.685 1.00 23.73 C ATOM 871 CD1 LEU A 104 14.508 18.880 24.087 1.00 22.20 C ATOM 872 CD2 LEU A 104 16.064 19.368 22.212 1.00 21.02 C ATOM 873 N GLU A 105 17.168 22.550 21.491 1.00 15.97 N ATOM 874 CA GLU A 105 16.803 23.331 20.318 1.00 13.71 C ATOM 875 C GLU A 105 16.630 22.462 19.074 1.00 16.93 C ATOM 876 O GLU A 105 17.076 21.320 19.029 1.00 16.45 O ATOM 877 CB GLU A 105 17.841 24.419 20.058 1.00 16.43 C ATOM 878 CG GLU A 105 19.202 23.888 19.652 1.00 18.10 C ATOM 879 CD GLU A 105 20.217 24.993 19.451 1.00 21.34 C ATOM 880 OE1 GLU A 105 19.852 26.168 19.643 1.00 23.69 O ATOM 881 OE2 GLU A 105 21.374 24.686 19.102 1.00 20.87 O ATOM 882 N CYS A 106 15.971 23.030 18.072 1.00 15.19 N ATOM 883 CA CYS A 106 15.690 22.327 16.827 1.00 15.81 C ATOM 884 C CYS A 106 16.584 22.852 15.712 1.00 14.51 C ATOM 885 O CYS A 106 16.845 24.046 15.629 1.00 15.77 O ATOM 886 CB CYS A 106 14.217 22.491 16.432 1.00 19.41 C ATOM 887 SG CYS A 106 13.073 21.446 17.356 1.00 25.82 S ATOM 888 N ILE A 107 17.037 21.947 14.850 1.00 12.75 N ATOM 889 CA ILE A 107 17.840 22.321 13.695 1.00 13.00 C ATOM 890 C ILE A 107 17.329 21.709 12.397 1.00 14.42 C ATOM 891 O ILE A 107 17.095 20.512 12.314 1.00 14.60 O ATOM 892 CB ILE A 107 19.315 21.906 13.850 1.00 15.91 C ATOM 893 CG1 ILE A 107 19.863 22.362 15.198 1.00 15.54 C ATOM 894 CG2 ILE A 107 20.146 22.496 12.724 1.00 16.59 C ATOM 895 CD1 ILE A 107 20.062 23.844 15.277 1.00 17.58 C ATOM 896 N LEU A 108 17.180 22.547 11.380 1.00 13.54 N ATOM 897 CA LEU A 108 16.954 22.071 10.028 1.00 13.83 C ATOM 898 C LEU A 108 18.208 22.410 9.243 1.00 16.56 C ATOM 899 O LEU A 108 18.380 23.534 8.794 1.00 15.79 O ATOM 900 CB LEU A 108 15.723 22.724 9.401 1.00 16.75 C ATOM 901 CG LEU A 108 14.373 22.237 9.928 1.00 17.72 C ATOM 902 CD1 LEU A 108 13.936 23.086 11.103 1.00 20.66 C ATOM 903 CD2 LEU A 108 13.325 22.259 8.845 1.00 20.50 C ATOM 904 N HIS A 109 19.094 21.429 9.118 1.00 15.37 N ATOM 905 CA HIS A 109 20.344 21.598 8.429 1.00 17.07 C ATOM 906 C HIS A 109 20.227 21.301 6.917 1.00 15.19 C ATOM 907 O HIS A 109 19.378 20.583 6.496 1.00 13.98 O ATOM 908 CB HIS A 109 21.400 20.691 9.051 1.00 18.39 C ATOM 909 CG HIS A 109 21.041 19.238 9.002 1.00 21.69 C ATOM 910 ND1 HIS A 109 21.342 18.420 7.936 1.00 22.95 N ATOM 911 CD2 HIS A 109 20.416 18.448 9.908 1.00 21.75 C ATOM 912 CE1 HIS A 109 20.912 17.196 8.186 1.00 21.76 C ATOM 913 NE2 HIS A 109 20.339 17.188 9.372 1.00 21.09 N ATOM 914 N GLY A 110 21.092 21.923 6.141 1.00 15.19 N ATOM 915 CA GLY A 110 21.198 21.606 4.730 1.00 15.64 C ATOM 916 C GLY A 110 21.121 20.119 4.436 1.00 19.49 C ATOM 917 O GLY A 110 21.794 19.314 5.075 1.00 20.33 O ATOM 918 N ASP A 111 20.291 19.758 3.463 1.00 16.90 N ATOM 919 CA ASP A 111 20.099 18.362 3.095 1.00 16.18 C ATOM 920 C ASP A 111 19.571 18.235 1.667 1.00 16.28 C ATOM 921 O ASP A 111 18.429 17.851 1.448 1.00 18.58 O ATOM 922 CB ASP A 111 19.148 17.681 4.080 1.00 16.29 C ATOM 923 CG ASP A 111 19.114 16.176 3.918 1.00 17.91 C ATOM 924 OD1 ASP A 111 19.960 15.633 3.183 1.00 18.08 O ATOM 925 OD2 ASP A 111 18.237 15.539 4.532 1.00 18.22 O ATOM 926 N SER A 112 20.422 18.563 0.702 1.00 19.05 N ATOM 927 CA SER A 112 20.024 18.624 -0.699 1.00 21.22 C ATOM 928 C SER A 112 19.655 17.250 -1.255 1.00 22.33 C ATOM 929 O SER A 112 18.945 17.148 -2.251 1.00 23.85 O ATOM 930 CB SER A 112 21.141 19.242 -1.536 1.00 25.65 C ATOM 931 OG SER A 112 22.163 18.297 -1.791 1.00 31.42 O ATOM 932 N ALA A 113 20.144 16.197 -0.606 1.00 19.77 N ATOM 933 CA ALA A 113 19.816 14.830 -0.999 1.00 19.83 C ATOM 934 C ALA A 113 18.481 14.376 -0.412 1.00 22.03 C ATOM 935 O ALA A 113 18.022 13.267 -0.673 1.00 20.76 O ATOM 936 CB ALA A 113 20.931 13.877 -0.590 1.00 23.68 C ATOM 937 N LYS A 114 17.882 15.242 0.397 1.00 19.65 N ATOM 938 CA LYS A 114 16.746 14.895 1.247 1.00 20.77 C ATOM 939 C LYS A 114 16.963 13.551 1.910 1.00 20.09 C ATOM 940 O LYS A 114 16.100 12.728 1.976 1.00 23.30 O ATOM 941 CB LYS A 114 15.425 14.952 0.511 1.00 21.98 C ATOM 942 CG LYS A 114 15.107 16.300 -0.090 1.00 24.51 C ATOM 943 CD LYS A 114 14.171 16.217 -1.276 1.00 27.43 C ATOM 944 CE LYS A 114 12.770 16.214 -0.872 1.00 27.82 C ATOM 945 NZ LYS A 114 11.824 16.032 -2.018 1.00 25.09 N ATOM 946 N ARG A 115 18.171 13.319 2.397 1.00 20.14 N ATOM 947 CA ARG A 115 18.507 12.124 3.168 1.00 18.60 C ATOM 948 C ARG A 115 17.596 11.817 4.350 1.00 21.41 C ATOM 949 O ARG A 115 17.287 10.676 4.611 1.00 17.75 O ATOM 950 CB ARG A 115 19.933 12.239 3.675 1.00 20.11 C ATOM 951 CG ARG A 115 20.410 11.122 4.508 1.00 21.55 C ATOM 952 CD ARG A 115 21.900 11.117 4.638 1.00 24.48 C ATOM 953 NE ARG A 115 22.280 10.314 5.773 1.00 29.57 N ATOM 954 CZ ARG A 115 23.524 10.113 6.166 1.00 27.93 C ATOM 955 NH1 ARG A 115 24.509 10.631 5.490 1.00 26.85 N ATOM 956 NH2 ARG A 115 23.751 9.399 7.234 1.00 30.45 N ATOM 957 N TYR A 116 17.154 12.863 5.045 1.00 19.14 N ATOM 958 CA TYR A 116 16.487 12.690 6.330 1.00 20.22 C ATOM 959 C TYR A 116 14.999 13.017 6.238 1.00 18.96 C ATOM 960 O TYR A 116 14.284 12.980 7.235 1.00 19.60 O ATOM 961 CB TYR A 116 17.150 13.567 7.393 1.00 18.62 C ATOM 962 CG TYR A 116 18.562 13.153 7.718 1.00 15.64 C ATOM 963 CD1 TYR A 116 18.818 11.988 8.423 1.00 19.12 C ATOM 964 CD2 TYR A 116 19.639 13.922 7.312 1.00 16.24 C ATOM 965 CE1 TYR A 116 20.111 11.606 8.718 1.00 23.11 C ATOM 966 CE2 TYR A 116 20.932 13.546 7.598 1.00 20.81 C ATOM 967 CZ TYR A 116 21.164 12.390 8.302 1.00 19.60 C ATOM 968 OH TYR A 116 22.452 12.014 8.589 1.00 21.74 O ATOM 969 N ASN A 117 14.540 13.344 5.038 1.00 19.47 N ATOM 970 CA ASN A 117 13.147 13.707 4.836 1.00 21.08 C ATOM 971 C ASN A 117 12.653 14.782 5.807 1.00 19.90 C ATOM 972 O ASN A 117 11.560 14.672 6.342 1.00 18.61 O ATOM 973 CB ASN A 117 12.245 12.468 4.909 1.00 24.31 C ATOM 974 CG ASN A 117 12.716 11.346 4.002 1.00 29.80 C ATOM 975 OD1 ASN A 117 13.190 11.586 2.893 1.00 37.07 O ATOM 976 ND2 ASN A 117 12.589 10.113 4.472 1.00 38.16 N ATOM 977 N MET A 118 13.462 15.815 6.022 1.00 20.08 N ATOM 978 CA MET A 118 13.041 16.983 6.783 1.00 19.62 C ATOM 979 C MET A 118 12.133 17.901 5.998 1.00 18.23 C ATOM 980 O MET A 118 12.369 18.152 4.827 1.00 21.39 O ATOM 981 CB MET A 118 14.250 17.807 7.249 1.00 17.88 C ATOM 982 CG MET A 118 15.156 17.170 8.236 1.00 16.69 C ATOM 983 SD MET A 118 16.529 18.219 8.728 1.00 18.52 S ATOM 984 CE MET A 118 17.547 18.179 7.351 1.00 20.79 C ATOM 985 N SER A 119 11.132 18.446 6.670 1.00 17.31 N ATOM 986 CA SER A 119 10.293 19.454 6.060 1.00 15.48 C ATOM 987 C SER A 119 9.733 20.414 7.090 1.00 17.46 C ATOM 988 O SER A 119 9.620 20.095 8.267 1.00 15.18 O ATOM 989 CB SER A 119 9.152 18.815 5.268 1.00 17.77 C ATOM 990 OG SER A 119 8.409 17.912 6.057 1.00 17.16 O ATOM 991 N ILE A 120 9.390 21.600 6.616 1.00 15.27 N ATOM 992 CA ILE A 120 8.595 22.541 7.372 1.00 13.31 C ATOM 993 C ILE A 120 7.612 23.184 6.412 1.00 15.85 C ATOM 994 O ILE A 120 7.993 23.645 5.350 1.00 17.23 O ATOM 995 CB ILE A 120 9.447 23.612 8.071 1.00 16.80 C ATOM 996 CG1 ILE A 120 8.541 24.608 8.792 1.00 15.59 C ATOM 997 CG2 ILE A 120 10.351 24.325 7.080 1.00 13.77 C ATOM 998 CD1 ILE A 120 9.280 25.688 9.484 1.00 18.34 C ATOM 999 N GLU A 121 6.340 23.179 6.785 1.00 15.27 N ATOM 1000 CA GLU A 121 5.300 23.794 5.974 1.00 17.50 C ATOM 1001 C GLU A 121 4.247 24.485 6.841 1.00 16.87 C ATOM 1002 O GLU A 121 3.931 24.030 7.936 1.00 17.65 O ATOM 1003 CB GLU A 121 4.641 22.757 5.060 1.00 17.46 C ATOM 1004 CG GLU A 121 5.578 22.129 4.029 1.00 21.63 C ATOM 1005 CD GLU A 121 5.833 23.026 2.827 1.00 27.79 C ATOM 1006 OE1 GLU A 121 5.224 24.110 2.744 1.00 23.19 O ATOM 1007 OE2 GLU A 121 6.644 22.640 1.961 1.00 25.54 O ATOM 1008 N LYS A 122 3.685 25.564 6.336 1.00 13.35 N ATOM 1009 CA LYS A 122 2.576 26.216 6.970 1.00 16.96 C ATOM 1010 C LYS A 122 1.393 25.298 7.087 1.00 17.19 C ATOM 1011 O LYS A 122 1.139 24.536 6.201 1.00 19.87 O ATOM 1012 CB LYS A 122 2.143 27.397 6.095 1.00 20.15 C ATOM 1013 CG LYS A 122 2.492 28.704 6.647 1.00 23.97 C ATOM 1014 CD LYS A 122 2.121 29.855 5.808 1.00 21.26 C ATOM 1015 CE LYS A 122 3.234 30.890 5.844 1.00 22.63 C ATOM 1016 NZ LYS A 122 2.797 32.266 5.553 1.00 25.50 N ATOM 1017 N VAL A 123 0.666 25.407 8.186 1.00 17.75 N ATOM 1018 CA VAL A 123 -0.652 24.808 8.330 1.00 17.64 C ATOM 1019 C VAL A 123 -1.708 25.901 8.390 1.00 19.62 C ATOM 1020 O VAL A 123 -1.592 26.836 9.175 1.00 18.93 O ATOM 1021 CB VAL A 123 -0.729 23.943 9.604 1.00 16.65 C ATOM 1022 CG1 VAL A 123 -2.033 23.168 9.654 1.00 19.99 C ATOM 1023 CG2 VAL A 123 0.457 23.002 9.672 1.00 16.32 C ATOM 1024 N ASP A 124 -2.730 25.787 7.549 1.00 20.20 N ATOM 1025 CA ASP A 124 -3.827 26.746 7.557 1.00 24.22 C ATOM 1026 C ASP A 124 -4.507 26.762 8.912 1.00 24.32 C ATOM 1027 O ASP A 124 -4.719 25.714 9.516 1.00 21.49 O ATOM 1028 CB ASP A 124 -4.857 26.420 6.476 1.00 24.07 C ATOM 1029 CG ASP A 124 -6.179 27.131 6.702 1.00 30.86 C ATOM 1030 OD1 ASP A 124 -6.217 28.370 6.569 1.00 36.55 O ATOM 1031 OD2 ASP A 124 -7.179 26.455 7.015 1.00 38.30 O ATOM 1032 N SER A 125 -4.810 27.951 9.395 1.00 24.15 N ATOM 1033 CA SER A 125 -5.248 28.171 10.760 1.00 27.35 C ATOM 1034 C SER A 125 -6.430 27.310 11.140 1.00 26.98 C ATOM 1035 O SER A 125 -6.636 27.035 12.283 1.00 25.70 O ATOM 1036 CB SER A 125 -5.610 29.629 10.960 1.00 24.78 C ATOM 1037 OG SER A 125 -5.986 29.864 12.294 1.00 36.53 O ATOM 1038 N GLU A 126 -7.190 26.917 10.143 1.00 25.96 N ATOM 1039 CA GLU A 126 -8.446 26.278 10.361 1.00 30.44 C ATOM 1040 C GLU A 126 -8.415 24.766 10.410 1.00 29.16 C ATOM 1041 O GLU A 126 -9.439 24.149 10.623 1.00 29.86 O ATOM 1042 CB GLU A 126 -9.418 26.724 9.284 1.00 32.53 C ATOM 1043 CG GLU A 126 -9.911 28.122 9.449 1.00 34.89 C ATOM 1044 CD GLU A 126 -10.910 28.446 8.401 1.00 43.93 C ATOM 1045 OE1 GLU A 126 -11.059 27.625 7.475 1.00 43.81 O ATOM 1046 OE2 GLU A 126 -11.560 29.492 8.511 1.00 50.09 O ATOM 1047 N GLU A 127 -7.241 24.180 10.189 1.00 26.87 N ATOM 1048 CA GLU A 127 -7.079 22.727 10.297 1.00 25.48 C ATOM 1049 C GLU A 127 -7.289 22.187 11.705 1.00 24.23 C ATOM 1050 O GLU A 127 -6.788 22.731 12.646 1.00 22.17 O ATOM 1051 CB GLU A 127 -5.750 22.236 9.755 1.00 26.86 C ATOM 1052 CG GLU A 127 -5.368 22.794 8.456 1.00 25.81 C ATOM 1053 CD GLU A 127 -6.051 22.132 7.280 1.00 32.37 C ATOM 1054 OE1 GLU A 127 -6.973 21.329 7.484 1.00 32.89 O ATOM 1055 OE2 GLU A 127 -5.659 22.449 6.138 1.00 32.64 O ATOM 1056 N PRO A 128 -8.031 21.077 11.810 1.00 20.95 N ATOM 1057 CA PRO A 128 -8.313 20.439 13.100 1.00 22.24 C ATOM 1058 C PRO A 128 -7.065 19.916 13.803 1.00 20.41 C ATOM 1059 O PRO A 128 -7.092 19.692 15.010 1.00 19.42 O ATOM 1060 CB PRO A 128 -9.239 19.274 12.727 1.00 23.25 C ATOM 1061 CG PRO A 128 -9.092 19.094 11.263 1.00 24.66 C ATOM 1062 CD PRO A 128 -8.766 20.434 10.709 1.00 26.77 C ATOM 1063 N GLU A 129 -6.011 19.684 13.055 1.00 20.65 N ATOM 1064 CA GLU A 129 -4.765 19.263 13.638 1.00 21.92 C ATOM 1065 C GLU A 129 -4.217 20.313 14.643 1.00 21.54 C ATOM 1066 O GLU A 129 -3.323 20.013 15.397 1.00 15.78 O ATOM 1067 CB GLU A 129 -3.718 19.026 12.562 1.00 23.83 C ATOM 1068 CG GLU A 129 -3.831 17.756 11.823 1.00 26.63 C ATOM 1069 CD GLU A 129 -4.875 17.804 10.740 1.00 30.85 C ATOM 1070 OE1 GLU A 129 -5.254 18.894 10.344 1.00 24.33 O ATOM 1071 OE2 GLU A 129 -5.335 16.741 10.331 1.00 31.72 O ATOM 1072 N LEU A 130 -4.776 21.525 14.616 1.00 19.09 N ATOM 1073 CA LEU A 130 -4.274 22.640 15.415 1.00 17.90 C ATOM 1074 C LEU A 130 -5.171 22.937 16.617 1.00 16.31 C ATOM 1075 O LEU A 130 -4.865 23.806 17.427 1.00 16.60 O ATOM 1076 CB LEU A 130 -4.129 23.899 14.557 1.00 16.56 C ATOM 1077 CG LEU A 130 -3.378 23.779 13.231 1.00 20.37 C ATOM 1078 CD1 LEU A 130 -3.742 24.932 12.315 1.00 22.81 C ATOM 1079 CD2 LEU A 130 -1.877 23.728 13.453 1.00 18.22 C ATOM 1080 N ASN A 131 -6.276 22.208 16.724 1.00 20.48 N ATOM 1081 CA ASN A 131 -7.219 22.395 17.818 1.00 19.20 C ATOM 1082 C ASN A 131 -6.574 22.255 19.195 1.00 19.78 C ATOM 1083 O ASN A 131 -6.877 23.016 20.111 1.00 20.44 O ATOM 1084 CB ASN A 131 -8.391 21.424 17.683 1.00 19.03 C ATOM 1085 CG ASN A 131 -9.313 21.784 16.538 1.00 22.61 C ATOM 1086 OD1 ASN A 131 -9.227 22.877 15.987 1.00 25.24 O ATOM 1087 ND2 ASN A 131 -10.199 20.864 16.172 1.00 24.56 N ATOM 1088 N GLU A 132 -5.729 21.243 19.368 1.00 17.16 N ATOM 1089 CA GLU A 132 -5.084 21.006 20.656 1.00 20.04 C ATOM 1090 C GLU A 132 -4.231 22.161 21.129 1.00 19.23 C ATOM 1091 O GLU A 132 -4.371 22.600 22.234 1.00 21.45 O ATOM 1092 CB GLU A 132 -4.237 19.759 20.672 1.00 21.80 C ATOM 1093 CG GLU A 132 -4.997 18.509 20.698 1.00 24.57 C ATOM 1094 CD GLU A 132 -4.116 17.286 20.731 1.00 33.02 C ATOM 1095 OE1 GLU A 132 -2.927 17.392 21.073 1.00 27.82 O ATOM 1096 OE2 GLU A 132 -4.624 16.212 20.388 1.00 38.05 O ATOM 1097 N ILE A 133 -3.325 22.617 20.275 1.00 19.64 N ATOM 1098 CA ILE A 133 -2.571 23.826 20.570 1.00 17.05 C ATOM 1099 C ILE A 133 -3.512 24.938 21.012 1.00 18.05 C ATOM 1100 O ILE A 133 -3.283 25.596 22.023 1.00 20.43 O ATOM 1101 CB ILE A 133 -1.772 24.305 19.344 1.00 15.84 C ATOM 1102 CG1 ILE A 133 -0.614 23.348 19.055 1.00 17.56 C ATOM 1103 CG2 ILE A 133 -1.267 25.722 19.558 1.00 18.40 C ATOM 1104 CD1 ILE A 133 -0.022 23.515 17.692 1.00 18.24 C ATOM 1105 N LYS A 134 -4.576 25.142 20.248 1.00 18.49 N ATOM 1106 CA LYS A 134 -5.540 26.184 20.565 1.00 22.16 C ATOM 1107 C LYS A 134 -6.168 25.994 21.948 1.00 21.85 C ATOM 1108 O LYS A 134 -6.323 26.952 22.698 1.00 20.77 O ATOM 1109 CB LYS A 134 -6.623 26.255 19.491 1.00 21.32 C ATOM 1110 CG LYS A 134 -6.115 26.731 18.145 1.00 21.94 C ATOM 1111 CD LYS A 134 -7.222 26.776 17.117 1.00 26.34 C ATOM 1112 CE LYS A 134 -6.692 27.213 15.766 1.00 25.52 C ATOM 1113 NZ LYS A 134 -7.755 27.251 14.737 1.00 26.26 N ATOM 1114 N SER A 135 -6.526 24.760 22.280 1.00 21.92 N ATOM 1115 CA SER A 135 -7.185 24.493 23.555 1.00 23.91 C ATOM 1116 C SER A 135 -6.217 24.594 24.732 1.00 22.34 C ATOM 1117 O SER A 135 -6.594 25.019 25.818 1.00 23.61 O ATOM 1118 CB SER A 135 -7.858 23.120 23.539 1.00 27.73 C ATOM 1119 OG SER A 135 -6.904 22.079 23.470 1.00 30.73 O ATOM 1120 N ARG A 136 -4.970 24.202 24.506 1.00 18.33 N ATOM 1121 CA ARG A 136 -3.942 24.307 25.531 1.00 17.89 C ATOM 1122 C ARG A 136 -3.552 25.759 25.800 1.00 18.90 C ATOM 1123 O ARG A 136 -3.174 26.112 26.914 1.00 21.91 O ATOM 1124 CB ARG A 136 -2.713 23.485 25.142 1.00 18.83 C ATOM 1125 CG ARG A 136 -2.852 22.002 25.447 1.00 18.71 C ATOM 1126 CD ARG A 136 -1.550 21.259 25.229 1.00 20.22 C ATOM 1127 NE ARG A 136 -1.045 21.423 23.871 1.00 19.74 N ATOM 1128 CZ ARG A 136 -1.067 20.473 22.942 1.00 19.54 C ATOM 1129 NH1 ARG A 136 -1.573 19.281 23.217 1.00 20.28 N ATOM 1130 NH2 ARG A 136 -0.587 20.720 21.735 1.00 18.00 N ATOM 1131 N LYS A 137 -3.664 26.599 24.775 1.00 18.53 N ATOM 1132 CA LYS A 137 -3.418 28.025 24.935 1.00 20.77 C ATOM 1133 C LYS A 137 -4.509 28.667 25.784 1.00 21.04 C ATOM 1134 O LYS A 137 -4.223 29.509 26.621 1.00 21.68 O ATOM 1135 CB LYS A 137 -3.326 28.734 23.587 1.00 18.23 C ATOM 1136 CG LYS A 137 -3.317 30.248 23.713 1.00 18.91 C ATOM 1137 CD LYS A 137 -2.735 30.929 22.493 1.00 20.27 C ATOM 1138 CE LYS A 137 -2.756 32.438 22.664 1.00 21.04 C ATOM 1139 NZ LYS A 137 -2.275 33.157 21.462 1.00 27.30 N ATOM 1140 N ARG A 138 -5.752 28.255 25.564 1.00 24.37 N ATOM 1141 CA ARG A 138 -6.869 28.759 26.352 1.00 23.97 C ATOM 1142 C ARG A 138 -6.656 28.452 27.826 1.00 26.51 C ATOM 1143 O ARG A 138 -6.866 29.301 28.685 1.00 30.01 O ATOM 1144 CB ARG A 138 -8.180 28.140 25.876 1.00 24.12 C ATOM 1145 CG ARG A 138 -8.573 28.527 24.470 1.00 26.71 C ATOM 1146 CD ARG A 138 -10.067 28.379 24.257 1.00 29.64 C ATOM 1147 NE ARG A 138 -10.493 26.996 24.402 1.00 31.96 N ATOM 1148 CZ ARG A 138 -10.391 26.079 23.446 1.00 33.95 C ATOM 1149 NH1 ARG A 138 -9.877 26.394 22.262 1.00 30.37 N ATOM 1150 NH2 ARG A 138 -10.806 24.843 23.674 1.00 35.67 N ATOM 1151 N LEU A 139 -6.238 27.227 28.112 1.00 25.58 N ATOM 1152 CA LEU A 139 -5.969 26.822 29.482 1.00 27.88 C ATOM 1153 C LEU A 139 -4.793 27.606 30.042 1.00 28.80 C ATOM 1154 O LEU A 139 -4.685 27.815 31.250 1.00 26.26 O ATOM 1155 CB LEU A 139 -5.675 25.326 29.545 1.00 29.66 C ATOM 1156 CG LEU A 139 -6.816 24.408 29.113 1.00 35.14 C ATOM 1157 CD1 LEU A 139 -6.578 22.997 29.607 1.00 39.86 C ATOM 1158 CD2 LEU A 139 -8.140 24.939 29.631 1.00 39.00 C ATOM 1159 N TYR A 140 -3.909 28.037 29.151 1.00 26.88 N ATOM 1160 CA TYR A 140 -2.692 28.716 29.565 1.00 24.71 C ATOM 1161 C TYR A 140 -2.981 30.165 29.931 1.00 27.15 C ATOM 1162 O TYR A 140 -2.522 30.659 30.956 1.00 30.16 O ATOM 1163 CB TYR A 140 -1.626 28.644 28.473 1.00 23.47 C ATOM 1164 CG TYR A 140 -0.361 29.365 28.857 1.00 23.62 C ATOM 1165 CD1 TYR A 140 0.695 28.689 29.450 1.00 22.51 C ATOM 1166 CD2 TYR A 140 -0.231 30.729 28.651 1.00 23.56 C ATOM 1167 CE1 TYR A 140 1.850 29.349 29.814 1.00 21.80 C ATOM 1168 CE2 TYR A 140 0.919 31.396 29.013 1.00 24.95 C ATOM 1169 CZ TYR A 140 1.955 30.703 29.596 1.00 21.97 C ATOM 1170 OH TYR A 140 3.098 31.368 29.956 1.00 21.99 O ATOM 1171 N VAL A 141 -3.716 30.837 29.074 1.00 29.13 N ATOM 1172 CA VAL A 141 -4.103 32.198 29.337 1.00 28.06 C ATOM 1173 C VAL A 141 -5.171 32.266 30.418 1.00 30.78 C ATOM 1174 O VAL A 141 -5.955 31.346 30.553 1.00 32.06 O ATOM 1175 CB VAL A 141 -4.609 32.891 28.083 1.00 30.81 C ATOM 1176 CG1 VAL A 141 -3.656 32.683 26.958 1.00 29.51 C ATOM 1177 CG2 VAL A 141 -5.927 32.396 27.726 1.00 33.50 C TER 1178 VAL A 141 ATOM 1179 O5' DG B 1 30.142 25.082 14.408 1.00 48.99 O ATOM 1180 C5' DG B 1 29.080 25.013 13.450 1.00 40.48 C ATOM 1181 C4' DG B 1 29.171 26.112 12.401 1.00 40.91 C ATOM 1182 O4' DG B 1 28.667 25.604 11.137 1.00 33.72 O ATOM 1183 C3' DG B 1 28.338 27.353 12.702 1.00 37.86 C ATOM 1184 O3' DG B 1 28.887 28.521 12.096 1.00 46.27 O ATOM 1185 C2' DG B 1 27.009 26.983 12.061 1.00 35.77 C ATOM 1186 C1' DG B 1 27.470 26.273 10.794 1.00 34.44 C ATOM 1187 N9 DG B 1 26.489 25.311 10.298 1.00 30.63 N ATOM 1188 C8 DG B 1 26.018 24.200 10.950 1.00 26.47 C ATOM 1189 N7 DG B 1 25.140 23.526 10.267 1.00 27.58 N ATOM 1190 C5 DG B 1 25.013 24.236 9.084 1.00 23.64 C ATOM 1191 C6 DG B 1 24.201 23.989 7.951 1.00 22.94 C ATOM 1192 O6 DG B 1 23.410 23.061 7.759 1.00 21.41 O ATOM 1193 N1 DG B 1 24.378 24.958 6.972 1.00 19.05 N ATOM 1194 C2 DG B 1 25.230 26.028 7.072 1.00 23.95 C ATOM 1195 N2 DG B 1 25.265 26.861 6.026 1.00 28.02 N ATOM 1196 N3 DG B 1 25.992 26.270 8.123 1.00 24.29 N ATOM 1197 C4 DG B 1 25.835 25.337 9.088 1.00 24.42 C ATOM 1198 P DG B 2 28.681 29.965 12.762 1.00 54.18 P ATOM 1199 OP1 DG B 2 29.080 31.009 11.799 1.00 46.45 O ATOM 1200 OP2 DG B 2 29.301 29.922 14.103 1.00 45.70 O ATOM 1201 O5' DG B 2 27.093 30.050 12.934 1.00 41.65 O ATOM 1202 C5' DG B 2 26.391 31.230 12.547 1.00 37.51 C ATOM 1203 C4' DG B 2 25.740 31.897 13.744 1.00 39.82 C ATOM 1204 O4' DG B 2 24.660 31.056 14.225 1.00 35.26 O ATOM 1205 C3' DG B 2 26.703 32.062 14.911 1.00 42.27 C ATOM 1206 O3' DG B 2 26.422 33.200 15.709 1.00 44.88 O ATOM 1207 C2' DG B 2 26.476 30.787 15.704 1.00 41.25 C ATOM 1208 C1' DG B 2 24.998 30.508 15.483 1.00 35.50 C ATOM 1209 N9 DG B 2 24.765 29.071 15.498 1.00 31.35 N ATOM 1210 C8 DG B 2 25.334 28.149 14.662 1.00 32.11 C ATOM 1211 N7 DG B 2 24.967 26.928 14.907 1.00 31.99 N ATOM 1212 C5 DG B 2 24.102 27.043 15.984 1.00 25.65 C ATOM 1213 C6 DG B 2 23.389 26.047 16.688 1.00 27.35 C ATOM 1214 O6 DG B 2 23.376 24.826 16.493 1.00 20.84 O ATOM 1215 N1 DG B 2 22.627 26.595 17.714 1.00 25.52 N ATOM 1216 C2 DG B 2 22.560 27.932 18.021 1.00 26.55 C ATOM 1217 N2 DG B 2 21.766 28.264 19.047 1.00 23.94 N ATOM 1218 N3 DG B 2 23.224 28.874 17.368 1.00 29.04 N ATOM 1219 C4 DG B 2 23.971 28.359 16.365 1.00 30.47 C ATOM 1220 P DT B 3 27.411 33.694 16.858 1.00 61.44 P ATOM 1221 OP1 DT B 3 27.286 35.161 16.933 1.00 58.94 O ATOM 1222 OP2 DT B 3 28.729 33.060 16.643 1.00 50.28 O ATOM 1223 O5' DT B 3 26.741 33.075 18.167 1.00 47.64 O ATOM 1224 C5' DT B 3 25.360 33.304 18.416 1.00 37.72 C ATOM 1225 C4' DT B 3 24.903 32.427 19.564 1.00 37.30 C ATOM 1226 O4' DT B 3 24.823 31.050 19.138 1.00 36.00 O ATOM 1227 C3' DT B 3 25.834 32.440 20.768 1.00 37.97 C ATOM 1228 O3' DT B 3 25.119 33.003 21.845 1.00 40.51 O ATOM 1229 C2' DT B 3 26.189 30.977 21.027 1.00 34.41 C ATOM 1230 C1' DT B 3 25.134 30.221 20.232 1.00 33.90 C ATOM 1231 N1 DT B 3 25.586 28.923 19.672 1.00 35.31 N ATOM 1232 C2 DT B 3 25.000 27.761 20.110 1.00 34.97 C ATOM 1233 O2 DT B 3 24.128 27.729 20.958 1.00 35.07 O ATOM 1234 N3 DT B 3 25.484 26.624 19.520 1.00 32.78 N ATOM 1235 C4 DT B 3 26.465 26.538 18.553 1.00 35.79 C ATOM 1236 O4 DT B 3 26.832 25.467 18.084 1.00 38.07 O ATOM 1237 C5 DT B 3 27.031 27.792 18.136 1.00 34.37 C ATOM 1238 C7 DT B 3 28.081 27.820 17.064 1.00 36.13 C ATOM 1239 C6 DT B 3 26.568 28.910 18.706 1.00 34.31 C ATOM 1240 P DA B 4 25.894 33.679 23.061 1.00 47.81 P ATOM 1241 OP1 DA B 4 26.486 34.941 22.579 1.00 41.81 O ATOM 1242 OP2 DA B 4 26.752 32.648 23.672 1.00 43.65 O ATOM 1243 O5' DA B 4 24.699 33.932 24.093 1.00 39.30 O ATOM 1244 C5' DA B 4 24.064 35.191 24.170 1.00 42.60 C ATOM 1245 C4' DA B 4 22.584 35.130 23.818 1.00 32.90 C ATOM 1246 O4' DA B 4 22.396 34.579 22.495 1.00 33.84 O ATOM 1247 C3' DA B 4 21.667 34.333 24.741 1.00 31.04 C ATOM 1248 O3' DA B 4 20.622 35.221 25.041 1.00 26.99 O ATOM 1249 C2' DA B 4 21.184 33.178 23.865 1.00 28.73 C ATOM 1250 C1' DA B 4 21.202 33.841 22.495 1.00 30.55 C ATOM 1251 N9 DA B 4 21.290 32.955 21.340 1.00 27.59 N ATOM 1252 C8 DA B 4 21.838 31.708 21.286 1.00 29.21 C ATOM 1253 N7 DA B 4 21.782 31.156 20.101 1.00 30.48 N ATOM 1254 C5 DA B 4 21.163 32.112 19.320 1.00 25.02 C ATOM 1255 C6 DA B 4 20.809 32.136 17.962 1.00 26.71 C ATOM 1256 N6 DA B 4 21.052 31.121 17.128 1.00 27.26 N ATOM 1257 N1 DA B 4 20.202 33.244 17.499 1.00 25.67 N ATOM 1258 C2 DA B 4 19.969 34.251 18.345 1.00 22.71 C ATOM 1259 N3 DA B 4 20.254 34.345 19.640 1.00 23.92 N ATOM 1260 C4 DA B 4 20.857 33.231 20.068 1.00 26.43 C ATOM 1261 P DA B 5 19.513 34.965 26.152 1.00 36.76 P ATOM 1262 OP1 DA B 5 19.466 36.180 26.992 1.00 35.72 O ATOM 1263 OP2 DA B 5 19.715 33.655 26.791 1.00 33.44 O ATOM 1264 O5' DA B 5 18.194 34.920 25.258 1.00 31.20 O ATOM 1265 C5' DA B 5 18.028 35.811 24.166 1.00 27.00 C ATOM 1266 C4' DA B 5 16.550 35.961 23.863 1.00 20.71 C ATOM 1267 O4' DA B 5 16.056 34.719 23.321 1.00 20.37 O ATOM 1268 C3' DA B 5 15.680 36.188 25.089 1.00 20.26 C ATOM 1269 O3' DA B 5 14.434 36.742 24.728 1.00 17.74 O ATOM 1270 C2' DA B 5 15.510 34.775 25.630 1.00 23.38 C ATOM 1271 C1' DA B 5 15.527 33.922 24.366 1.00 26.33 C ATOM 1272 N9 DA B 5 16.382 32.747 24.499 1.00 30.26 N ATOM 1273 C8 DA B 5 17.633 32.701 25.044 1.00 29.69 C ATOM 1274 N7 DA B 5 18.178 31.512 25.033 1.00 32.52 N ATOM 1275 C5 DA B 5 17.210 30.723 24.428 1.00 28.91 C ATOM 1276 C6 DA B 5 17.165 29.353 24.115 1.00 30.49 C ATOM 1277 N6 DA B 5 18.157 28.501 24.371 1.00 29.49 N ATOM 1278 N1 DA B 5 16.051 28.890 23.521 1.00 29.07 N ATOM 1279 C2 DA B 5 15.057 29.742 23.264 1.00 26.17 C ATOM 1280 N3 DA B 5 14.977 31.041 23.516 1.00 26.57 N ATOM 1281 C4 DA B 5 16.099 31.470 24.099 1.00 21.95 C ATOM 1282 P DC B 6 14.246 38.322 24.824 1.00 18.46 P ATOM 1283 OP1 DC B 6 14.624 38.770 26.175 1.00 20.94 O ATOM 1284 OP2 DC B 6 12.909 38.661 24.307 1.00 19.78 O ATOM 1285 O5' DC B 6 15.343 38.839 23.790 1.00 19.13 O ATOM 1286 C5' DC B 6 14.962 39.502 22.604 1.00 21.15 C ATOM 1287 C4' DC B 6 15.768 40.780 22.464 1.00 17.66 C ATOM 1288 O4' DC B 6 17.179 40.465 22.399 1.00 18.29 O ATOM 1289 C3' DC B 6 15.459 41.644 21.240 1.00 18.17 C ATOM 1290 O3' DC B 6 15.284 42.973 21.653 1.00 19.76 O ATOM 1291 C2' DC B 6 16.725 41.544 20.404 1.00 21.28 C ATOM 1292 C1' DC B 6 17.764 41.376 21.502 1.00 18.86 C ATOM 1293 N1 DC B 6 19.035 40.832 20.994 1.00 20.82 N ATOM 1294 C2 DC B 6 20.121 41.695 20.833 1.00 19.95 C ATOM 1295 O2 DC B 6 19.996 42.882 21.132 1.00 21.75 O ATOM 1296 N3 DC B 6 21.282 41.204 20.358 1.00 20.32 N ATOM 1297 C4 DC B 6 21.377 39.919 20.047 1.00 26.02 C ATOM 1298 N4 DC B 6 22.550 39.489 19.582 1.00 27.63 N ATOM 1299 C5 DC B 6 20.281 39.018 20.198 1.00 22.79 C ATOM 1300 C6 DC B 6 19.136 39.515 20.671 1.00 22.20 C ATOM 1301 P DG B 7 14.112 43.875 21.079 1.00 20.25 P ATOM 1302 OP1 DG B 7 14.030 45.059 21.959 1.00 19.65 O ATOM 1303 OP2 DG B 7 12.927 43.024 20.868 1.00 19.53 O ATOM 1304 O5' DG B 7 14.683 44.337 19.662 1.00 17.47 O ATOM 1305 C5' DG B 7 15.754 45.265 19.607 1.00 19.55 C ATOM 1306 C4' DG B 7 16.385 45.310 18.228 1.00 21.30 C ATOM 1307 O4' DG B 7 16.978 44.027 17.890 1.00 18.19 O ATOM 1308 C3' DG B 7 15.424 45.620 17.092 1.00 22.64 C ATOM 1309 O3' DG B 7 16.151 46.264 16.058 1.00 23.39 O ATOM 1310 C2' DG B 7 14.968 44.221 16.689 1.00 20.98 C ATOM 1311 C1' DG B 7 16.268 43.432 16.826 1.00 18.01 C ATOM 1312 N9 DG B 7 16.118 42.014 17.142 1.00 17.30 N ATOM 1313 C8 DG B 7 15.002 41.371 17.611 1.00 17.43 C ATOM 1314 N7 DG B 7 15.180 40.096 17.804 1.00 16.00 N ATOM 1315 C5 DG B 7 16.505 39.878 17.448 1.00 16.09 C ATOM 1316 C6 DG B 7 17.276 38.692 17.447 1.00 19.52 C ATOM 1317 O6 DG B 7 16.924 37.557 17.776 1.00 21.19 O ATOM 1318 N1 DG B 7 18.579 38.907 17.006 1.00 16.54 N ATOM 1319 C2 DG B 7 19.074 40.125 16.614 1.00 19.47 C ATOM 1320 N2 DG B 7 20.354 40.147 16.217 1.00 17.67 N ATOM 1321 N3 DG B 7 18.363 41.243 16.612 1.00 14.81 N ATOM 1322 C4 DG B 7 17.095 41.049 17.038 1.00 16.81 C ATOM 1323 P DG B 8 15.518 47.439 15.182 1.00 27.73 P ATOM 1324 OP1 DG B 8 16.532 47.881 14.200 1.00 28.84 O ATOM 1325 OP2 DG B 8 14.877 48.431 16.064 1.00 26.37 O ATOM 1326 O5' DG B 8 14.361 46.657 14.406 1.00 24.38 O ATOM 1327 C5' DG B 8 14.667 45.999 13.187 1.00 26.33 C ATOM 1328 C4' DG B 8 13.424 45.486 12.480 1.00 26.13 C ATOM 1329 O4' DG B 8 12.996 44.239 13.073 1.00 25.38 O ATOM 1330 C3' DG B 8 12.195 46.384 12.511 1.00 26.79 C ATOM 1331 O3' DG B 8 11.512 46.246 11.278 1.00 28.34 O ATOM 1332 C2' DG B 8 11.373 45.811 13.666 1.00 23.30 C ATOM 1333 C1' DG B 8 11.647 44.327 13.483 1.00 21.60 C ATOM 1334 N9 DG B 8 11.564 43.503 14.678 1.00 19.56 N ATOM 1335 C8 DG B 8 11.884 43.846 15.966 1.00 19.83 C ATOM 1336 N7 DG B 8 11.721 42.873 16.814 1.00 19.24 N ATOM 1337 C5 DG B 8 11.272 41.814 16.036 1.00 19.41 C ATOM 1338 C6 DG B 8 10.929 40.490 16.398 1.00 18.80 C ATOM 1339 O6 DG B 8 10.949 39.968 17.518 1.00 20.19 O ATOM 1340 N1 DG B 8 10.524 39.745 15.296 1.00 17.55 N ATOM 1341 C2 DG B 8 10.460 40.216 14.009 1.00 18.64 C ATOM 1342 N2 DG B 8 10.046 39.345 13.079 1.00 14.94 N ATOM 1343 N3 DG B 8 10.780 41.451 13.656 1.00 17.68 N ATOM 1344 C4 DG B 8 11.176 42.187 14.717 1.00 21.11 C ATOM 1345 P DT B 9 12.008 47.057 9.986 1.00 38.35 P ATOM 1346 OP1 DT B 9 12.491 48.375 10.437 1.00 25.33 O ATOM 1347 OP2 DT B 9 10.954 46.961 8.958 1.00 36.25 O ATOM 1348 O5' DT B 9 13.262 46.213 9.468 1.00 30.98 O ATOM 1349 C5' DT B 9 14.464 46.892 9.140 1.00 27.62 C ATOM 1350 C4' DT B 9 15.634 45.937 8.981 1.00 28.99 C ATOM 1351 O4' DT B 9 15.567 44.912 9.992 1.00 22.13 O ATOM 1352 C3' DT B 9 15.682 45.161 7.677 1.00 29.23 C ATOM 1353 O3' DT B 9 16.320 45.940 6.682 1.00 38.67 O ATOM 1354 C2' DT B 9 16.541 43.958 8.042 1.00 22.86 C ATOM 1355 C1' DT B 9 16.330 43.810 9.547 1.00 24.51 C ATOM 1356 N1 DT B 9 15.616 42.565 9.910 1.00 19.16 N ATOM 1357 C2 DT B 9 16.343 41.414 10.083 1.00 20.25 C ATOM 1358 O2 DT B 9 17.547 41.368 9.950 1.00 16.96 O ATOM 1359 N3 DT B 9 15.597 40.318 10.420 1.00 16.16 N ATOM 1360 C4 DT B 9 14.229 40.259 10.596 1.00 19.29 C ATOM 1361 O4 DT B 9 13.655 39.221 10.899 1.00 14.95 O ATOM 1362 C5 DT B 9 13.531 41.506 10.399 1.00 19.05 C ATOM 1363 C7 DT B 9 12.044 41.583 10.559 1.00 20.46 C ATOM 1364 C6 DT B 9 14.249 42.583 10.069 1.00 20.68 C TER 1365 DT B 9 HETATM 1366 O HOH A 201 2.150 19.830 19.021 1.00 14.69 O HETATM 1367 O HOH A 202 10.654 33.187 1.889 1.00 13.94 O HETATM 1368 O HOH A 203 15.525 26.485 22.357 1.00 17.18 O HETATM 1369 O HOH A 204 8.181 26.314 32.998 1.00 15.08 O HETATM 1370 O HOH A 205 8.191 12.732 16.696 1.00 21.11 O HETATM 1371 O HOH A 206 17.770 34.727 6.545 1.00 15.84 O HETATM 1372 O HOH A 207 5.764 37.366 19.328 1.00 20.75 O HETATM 1373 O HOH A 208 8.022 29.911 26.283 1.00 15.34 O HETATM 1374 O HOH A 209 10.622 28.936 26.297 1.00 12.70 O HETATM 1375 O HOH A 210 -0.039 31.989 20.398 1.00 20.45 O HETATM 1376 O HOH A 211 -0.610 19.651 19.285 1.00 17.59 O HETATM 1377 O HOH A 212 10.082 39.123 20.971 1.00 16.78 O HETATM 1378 O HOH A 213 2.803 17.657 17.569 1.00 17.71 O HETATM 1379 O HOH A 214 -2.858 20.794 17.934 1.00 19.93 O HETATM 1380 O HOH A 215 5.711 23.800 23.386 1.00 18.24 O HETATM 1381 O HOH A 216 16.823 34.862 17.020 1.00 15.03 O HETATM 1382 O HOH A 217 20.468 9.632 20.290 1.00 18.84 O HETATM 1383 O HOH A 218 -5.912 18.656 17.323 1.00 23.46 O HETATM 1384 O HOH A 219 17.878 33.125 21.480 1.00 19.99 O HETATM 1385 O HOH A 220 18.307 36.946 5.013 1.00 23.72 O HETATM 1386 O HOH A 221 15.711 16.284 4.394 1.00 20.13 O HETATM 1387 O HOH A 222 6.359 19.464 7.308 1.00 18.17 O HETATM 1388 O HOH A 223 0.765 21.898 5.540 1.00 22.39 O HETATM 1389 O HOH A 224 21.347 29.658 5.936 1.00 18.48 O HETATM 1390 O HOH A 225 8.943 45.700 17.582 1.00 30.19 O HETATM 1391 O HOH A 226 15.783 37.161 32.778 1.00 19.12 O HETATM 1392 O HOH A 227 21.022 33.903 5.623 1.00 21.38 O HETATM 1393 O HOH A 228 14.911 18.672 3.869 1.00 17.16 O HETATM 1394 O HOH A 229 -1.553 17.128 18.850 1.00 27.05 O HETATM 1395 O HOH A 230 -2.808 33.136 17.650 1.00 24.91 O HETATM 1396 O HOH A 231 2.524 20.611 29.701 1.00 19.71 O HETATM 1397 O HOH A 232 20.353 14.357 14.327 1.00 24.90 O HETATM 1398 O HOH A 233 -6.657 31.868 23.732 1.00 33.76 O HETATM 1399 O HOH A 234 2.964 36.974 25.948 1.00 23.62 O HETATM 1400 O HOH A 235 0.860 33.171 24.588 1.00 20.47 O HETATM 1401 O HOH A 236 7.127 12.692 10.535 1.00 26.94 O HETATM 1402 O HOH A 237 3.794 25.764 3.363 1.00 21.18 O HETATM 1403 O HOH A 238 -3.092 29.095 19.014 1.00 20.00 O HETATM 1404 O HOH A 239 -6.835 18.627 8.244 1.00 24.97 O HETATM 1405 O HOH A 240 12.905 34.790 21.798 1.00 24.11 O HETATM 1406 O HOH A 241 13.986 25.459 24.584 1.00 21.90 O HETATM 1407 O HOH A 242 25.205 30.740 6.802 1.00 24.36 O HETATM 1408 O HOH A 243 -0.921 29.223 9.782 1.00 22.10 O HETATM 1409 O HOH A 244 24.661 13.484 7.802 1.00 24.27 O HETATM 1410 O HOH A 245 1.192 10.725 15.023 1.00 29.95 O HETATM 1411 O HOH A 246 15.097 36.164 20.624 1.00 21.07 O HETATM 1412 O HOH A 247 14.359 42.381 25.825 1.00 22.44 O HETATM 1413 O HOH A 248 10.487 44.365 27.749 1.00 26.46 O HETATM 1414 O HOH A 249 18.506 34.157 12.763 1.00 16.69 O HETATM 1415 O HOH A 250 -6.756 29.634 21.972 1.00 22.66 O HETATM 1416 O HOH A 251 0.708 35.139 11.148 1.00 22.47 O HETATM 1417 O HOH A 252 2.322 17.132 27.294 1.00 20.16 O HETATM 1418 O HOH A 253 -6.528 30.832 33.308 1.00 35.64 O HETATM 1419 O HOH A 254 2.645 21.967 31.987 1.00 24.46 O HETATM 1420 O HOH A 255 25.819 30.915 3.122 1.00 37.51 O HETATM 1421 O HOH A 256 13.787 35.329 28.998 1.00 22.01 O HETATM 1422 O HOH A 257 10.680 45.418 25.433 1.00 24.40 O HETATM 1423 O HOH A 258 16.333 19.525 1.663 1.00 20.49 O HETATM 1424 O HOH A 259 2.893 28.107 -0.207 1.00 24.11 O HETATM 1425 O HOH A 260 15.182 37.571 28.607 1.00 19.06 O HETATM 1426 O HOH A 261 23.175 31.097 2.682 1.00 28.49 O HETATM 1427 O HOH A 262 2.166 19.736 5.043 1.00 27.93 O HETATM 1428 O HOH A 263 17.303 11.420 23.359 1.00 26.37 O HETATM 1429 O HOH A 264 7.365 45.040 13.720 1.00 28.13 O HETATM 1430 O HOH A 265 7.500 39.888 27.264 1.00 23.15 O HETATM 1431 O HOH A 266 8.981 15.507 5.332 1.00 18.40 O HETATM 1432 O HOH A 267 5.139 27.030 -0.902 1.00 24.99 O HETATM 1433 O HOH A 268 5.057 40.009 32.027 1.00 23.33 O HETATM 1434 O HOH A 269 9.268 45.303 21.824 1.00 26.83 O HETATM 1435 O HOH A 270 27.852 34.957 12.408 1.00 40.08 O HETATM 1436 O HOH A 271 20.494 29.824 24.377 1.00 27.00 O HETATM 1437 O HOH A 272 0.804 15.554 17.724 1.00 23.97 O HETATM 1438 O HOH A 273 -0.398 17.935 26.981 1.00 26.57 O HETATM 1439 O HOH A 274 -11.564 23.163 8.934 1.00 37.19 O HETATM 1440 O HOH A 275 9.072 16.212 2.577 1.00 31.45 O HETATM 1441 O HOH A 276 -3.045 23.537 5.537 1.00 28.65 O HETATM 1442 O HOH A 277 22.293 16.820 -3.888 1.00 32.54 O HETATM 1443 O HOH A 278 -5.337 30.370 19.653 1.00 22.61 O HETATM 1444 O HOH A 279 13.773 11.853 0.996 1.00 34.17 O HETATM 1445 O HOH A 280 23.585 12.855 1.847 1.00 32.67 O HETATM 1446 O HOH A 281 22.230 10.854 0.823 1.00 26.70 O HETATM 1447 O HOH A 282 -9.139 29.326 20.616 1.00 31.32 O HETATM 1448 O HOH A 283 19.720 10.780 -0.011 1.00 28.84 O HETATM 1449 O HOH A 284 3.210 35.360 17.647 1.00 21.63 O HETATM 1450 O HOH A 285 1.973 33.770 31.340 1.00 29.31 O HETATM 1451 O HOH A 286 6.085 19.448 2.530 1.00 29.50 O HETATM 1452 O HOH A 287 24.592 18.308 9.401 1.00 32.18 O HETATM 1453 O HOH A 288 10.357 12.395 13.130 1.00 25.72 O HETATM 1454 O HOH A 289 -2.987 17.453 16.513 1.00 31.25 O HETATM 1455 O HOH A 290 16.634 18.936 -2.724 1.00 25.31 O HETATM 1456 O HOH A 291 -9.542 24.293 19.887 1.00 27.62 O HETATM 1457 O HOH A 292 22.336 8.391 2.204 1.00 31.33 O HETATM 1458 O HOH A 293 10.849 15.076 26.680 1.00 24.24 O HETATM 1459 O HOH A 294 17.129 23.152 31.448 1.00 29.48 O HETATM 1460 O HOH A 295 21.982 34.085 13.034 1.00 26.54 O HETATM 1461 O HOH A 296 24.098 14.719 5.590 1.00 31.61 O HETATM 1462 O HOH A 297 4.537 38.987 17.060 1.00 24.13 O HETATM 1463 O HOH A 298 23.479 20.457 13.245 1.00 30.03 O HETATM 1464 O HOH A 299 10.707 11.242 17.382 1.00 29.95 O HETATM 1465 O HOH A 300 4.611 18.673 5.405 1.00 25.93 O HETATM 1466 O HOH A 301 16.358 35.026 31.155 1.00 25.01 O HETATM 1467 O HOH A 302 -0.500 13.870 16.393 1.00 31.85 O HETATM 1468 O HOH A 303 19.604 31.091 31.265 1.00 29.87 O HETATM 1469 O HOH A 304 -4.610 33.063 20.128 1.00 32.11 O HETATM 1470 O HOH A 305 16.404 10.057 15.335 1.00 24.92 O HETATM 1471 O HOH A 306 7.411 37.483 10.963 1.00 22.84 O HETATM 1472 O HOH A 307 3.397 34.950 4.042 1.00 29.51 O HETATM 1473 O HOH A 308 -1.778 21.312 6.216 1.00 32.40 O HETATM 1474 O HOH A 309 1.885 37.653 16.519 1.00 33.85 O HETATM 1475 O HOH A 310 2.670 45.271 18.521 1.00 36.50 O HETATM 1476 O HOH A 311 4.198 44.155 22.171 1.00 30.12 O HETATM 1477 O HOH A 312 24.938 35.932 3.481 1.00 41.72 O HETATM 1478 O HOH A 313 9.531 47.784 25.646 1.00 22.56 O HETATM 1479 O HOH A 314 13.532 27.741 24.117 1.00 22.80 O HETATM 1480 O HOH A 315 19.410 9.791 23.027 1.00 22.73 O HETATM 1481 O HOH A 316 24.828 15.364 9.649 1.00 21.72 O HETATM 1482 O HOH A 317 23.126 29.836 23.754 1.00 33.36 O HETATM 1483 O HOH A 318 18.488 15.035 16.016 1.00 23.59 O HETATM 1484 O HOH A 319 11.900 18.224 -3.509 1.00 23.12 O HETATM 1485 O HOH A 320 24.562 29.590 1.663 1.00 38.04 O HETATM 1486 O HOH A 321 13.772 10.384 11.570 1.00 24.27 O HETATM 1487 O HOH A 322 6.585 45.952 18.898 1.00 33.50 O HETATM 1488 O HOH A 323 -1.309 28.118 4.341 1.00 32.28 O HETATM 1489 O HOH A 324 0.128 25.153 30.697 1.00 30.47 O HETATM 1490 O HOH A 325 12.587 16.796 28.346 1.00 27.51 O HETATM 1491 O HOH A 326 -1.119 32.926 31.865 1.00 33.71 O HETATM 1492 O HOH A 327 -2.314 32.152 12.693 1.00 27.63 O HETATM 1493 O HOH A 328 -1.399 34.709 29.553 1.00 34.19 O HETATM 1494 O HOH A 329 11.942 16.780 2.263 1.00 27.64 O HETATM 1495 O HOH A 330 -6.624 26.533 32.857 1.00 32.46 O HETATM 1496 O HOH A 331 -7.310 30.642 17.987 1.00 30.39 O HETATM 1497 O HOH A 332 -3.918 16.596 17.887 1.00 34.11 O HETATM 1498 O HOH A 333 11.451 42.641 6.394 1.00 34.23 O HETATM 1499 O HOH A 334 -1.033 14.518 11.079 1.00 37.68 O HETATM 1500 O HOH A 335 8.370 43.203 12.713 1.00 30.04 O HETATM 1501 O HOH A 336 -4.587 32.656 13.416 1.00 30.05 O HETATM 1502 O HOH A 337 1.099 13.652 19.773 1.00 33.18 O HETATM 1503 O HOH A 338 4.812 14.444 27.192 1.00 31.15 O HETATM 1504 O HOH A 339 23.711 32.759 4.060 1.00 33.63 O HETATM 1505 O HOH A 340 14.907 11.153 9.411 1.00 24.74 O HETATM 1506 O HOH A 341 23.168 10.378 -1.913 1.00 32.67 O HETATM 1507 O HOH A 342 1.265 33.867 18.349 1.00 27.75 O HETATM 1508 O HOH A 343 2.716 41.289 24.112 1.00 33.94 O HETATM 1509 O HOH A 344 -1.424 24.320 28.209 1.00 30.82 O HETATM 1510 O HOH A 345 -2.434 22.030 29.032 1.00 34.10 O HETATM 1511 O HOH A 346 -8.111 17.554 18.487 1.00 30.14 O HETATM 1512 O HOH A 347 12.509 13.843 20.015 1.00 25.64 O HETATM 1513 O HOH A 348 8.782 36.021 7.758 1.00 27.52 O HETATM 1514 O HOH A 349 22.699 27.005 31.596 1.00 39.79 O HETATM 1515 O HOH A 350 2.755 18.633 30.103 1.00 29.78 O HETATM 1516 O HOH A 351 11.031 12.588 27.596 1.00 32.84 O HETATM 1517 O HOH A 352 7.253 15.992 29.856 1.00 31.33 O HETATM 1518 O HOH A 353 19.958 7.591 2.232 1.00 39.71 O HETATM 1519 O HOH A 354 -7.949 29.936 31.744 1.00 41.00 O HETATM 1520 O HOH A 355 26.058 26.045 2.836 1.00 39.76 O HETATM 1521 O HOH A 356 2.215 35.115 28.003 1.00 25.43 O HETATM 1522 O HOH A 357 6.427 18.362 30.558 1.00 28.95 O HETATM 1523 O HOH A 358 0.484 36.901 9.084 1.00 31.85 O HETATM 1524 O HOH A 359 6.951 17.376 1.664 1.00 32.81 O HETATM 1525 O HOH A 360 11.298 43.248 29.579 1.00 33.39 O HETATM 1526 O HOH A 361 7.418 10.712 21.003 1.00 36.04 O HETATM 1527 O HOH A 362 0.644 29.073 2.521 1.00 29.83 O HETATM 1528 O HOH A 363 -3.114 19.377 4.544 1.00 40.69 O HETATM 1529 O HOH A 364 15.165 9.043 13.449 1.00 37.46 O HETATM 1530 O HOH B 101 11.666 37.630 10.550 1.00 16.93 O HETATM 1531 O HOH B 102 19.115 34.550 15.305 1.00 19.52 O HETATM 1532 O HOH B 103 12.245 40.593 19.733 1.00 14.31 O HETATM 1533 O HOH B 104 20.119 43.572 16.537 1.00 21.49 O HETATM 1534 O HOH B 105 13.094 44.695 24.885 1.00 22.72 O HETATM 1535 O HOH B 106 19.683 39.157 6.381 1.00 25.24 O HETATM 1536 O HOH B 107 20.298 36.813 16.275 1.00 20.80 O HETATM 1537 O HOH B 108 12.053 37.529 22.183 1.00 20.92 O HETATM 1538 O HOH B 109 17.752 36.867 28.981 1.00 25.79 O HETATM 1539 O HOH B 110 12.877 47.806 16.392 1.00 29.40 O HETATM 1540 O HOH B 111 20.436 33.168 29.363 1.00 27.43 O HETATM 1541 O HOH B 112 23.090 24.140 13.636 1.00 20.50 O HETATM 1542 O HOH B 113 17.199 48.873 11.810 1.00 24.33 O HETATM 1543 O HOH B 114 22.918 36.354 20.949 1.00 32.56 O HETATM 1544 O HOH B 115 8.767 40.234 10.125 1.00 24.48 O HETATM 1545 O HOH B 116 26.610 37.311 23.868 1.00 38.73 O HETATM 1546 O HOH B 117 22.383 36.716 18.105 1.00 30.69 O HETATM 1547 O HOH B 118 22.062 38.006 14.368 1.00 28.80 O HETATM 1548 O HOH B 119 14.784 49.628 10.732 1.00 34.83 O HETATM 1549 O HOH B 120 10.044 38.625 8.822 1.00 31.56 O HETATM 1550 O HOH B 121 25.183 38.890 23.769 1.00 35.13 O HETATM 1551 O HOH B 122 26.482 28.969 3.690 1.00 39.44 O HETATM 1552 O HOH B 123 18.282 36.538 20.410 1.00 26.87 O HETATM 1553 O HOH B 124 23.860 21.217 11.038 1.00 38.18 O HETATM 1554 O HOH B 125 20.006 40.445 8.785 1.00 27.25 O HETATM 1555 O HOH B 126 10.651 44.407 19.546 1.00 29.06 O HETATM 1556 O HOH B 127 12.173 47.275 21.732 1.00 34.16 O HETATM 1557 O HOH B 128 9.980 40.318 7.016 1.00 29.77 O MASTER 314 0 0 3 7 0 0 6 1555 2 0 12 END
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Complexes with the same small molecule ligand
PDB Code
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Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
4hio
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Protection of telomeres protein 1, Pot1pC
Ligand Name
9-mer ssDNA (GGTAACGGT) T4A
EC.Number
E.C.-.-.-.-
Resolution
1.75(Å)
Affinity (Kd/Ki/IC50)
Kd=21nM
Release Year
2012
Protein/NA Sequence
Check fasta file
Primary Reference
(2013) Structure Vol. 21: pp. 121-132
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
O13988
Entrez Gene ID
NCBI Entrez Gene ID:
2542703
ASD
Information of known allosteric effects of PDB entries
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