Browse entries in the PDBbind-CN Database

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Related entries of code: 4j7e
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1ttvRCSB PDB    PDBbind107aa, >1TTV_1|Chain... *
4ipfRCSB PDB    PDBbind85aa, >4IPF_1|Chain... at 100%
4j3eRCSB PDB    PDBbind86aa, >4J3E_1|Chain... at 98%
4j74RCSB PDB    PDBbind86aa, >4J74_1|Chain... at 98%
4j7dRCSB PDB    PDBbind86aa, >4J7D_1|Chain... at 98%
4jrgRCSB PDB    PDBbind85aa, >4JRG_1|Chains... at 100%
4jscRCSB PDB    PDBbind86aa, >4JSC_1|Chains... at 98%
4lwtRCSB PDB    PDBbind86aa, >4LWT_1|Chain... at 98%
4lwuRCSB PDB    PDBbind85aa, >4LWU_1|Chain... at 100%
4lwvRCSB PDB    PDBbind85aa, >4LWV_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4j7e
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameE3 ubiquitin-protein ligase Mdm2 (I50L, P92H, L95I mutation)
Ligand NameI29
EC.Number E.C.6.3.2
Resolution 1.63(Å)
Affinity (Kd/Ki/IC50)Kd=14uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) ACS MED.CHEM.LETT. Vol. 4: pp. 660-665
Ligand Properties
Formula C27H35Cl2N4O3S
Molecular Weight 566.563
Exact Mass 565.181
No. of atoms 72
No. of bonds 75
Polar Surface Area 82.87
LOGP Value 3.60      (Computed with XLOGP3)
5.57      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P56273  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
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