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Related entries of code: 4jz1
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2gv6RCSB PDB    PDBbind241aa, >2GV6_1|Chain... at 100%
2gv7RCSB PDB    PDBbind241aa, >2GV7_1|Chain... at 100%
4jytRCSB PDB    PDBbind241aa, >4JYT_1|Chain... at 100%
4jziRCSB PDB    PDBbind241aa, >4JZI_1|Chain... at 100%
4o97RCSB PDB    PDBbind241aa, >4O97_1|Chain... at 100%
4o9vRCSB PDB    PDBbind241aa, >4O9V_1|Chain... at 100%
4r0iRCSB PDB    PDBbind241aa, >4R0I_1|Chain... at 100%
6n4tRCSB PDB    PDBbind241aa, >6N4T_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID4jz1
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameSuppressor of tumorigenicity 14 protein, Matriptase
Ligand NameF4D
EC.Number E.C.3.4.21.109
Resolution 1.9(Å)
Affinity (Kd/Ki/IC50)Ki=0.2uM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) ACS MED.CHEM.LETT. Vol. 4: pp. 1152-1157
Ligand Properties
Formula C25H23FN6O4S
Molecular Weight 522.551
Exact Mass 522.149
No. of atoms 60
No. of bonds 63
Polar Surface Area 189.12
LOGP Value 6.78      (Computed with XLOGP3)
3.09      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9Y5Y6  
Entrez Gene IDNCBI Entrez Gene ID: 6768  
ASDInformation of known allosteric effects of PDB entries

 
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