Browse entries in the PDBbind-CN Database

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Related entries of code: 4lxz
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3maxRCSB PDB    PDBbind367aa, >3MAX_1|Chains... at 93%
4ly1RCSB PDB    PDBbind369aa, >4LY1_1|Chains... at 93%
5iwgRCSB PDB    PDBbind368aa, >5IWG_1|Chains... at 93%
5ix0RCSB PDB    PDBbind369aa, >5IX0_1|Chains... at 93%
6g3oRCSB PDB    PDBbind370aa, >6G3O_1|Chains... at 93%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
1t69RCSB PDB    PDBbindSHH
1zz1RCSB PDB    PDBbindSHH
3c0zRCSB PDB    PDBbindSHH
5eeiRCSB PDB    PDBbindSHH
Entry Information
PDB ID4lxz
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameHistone deacetylase 2
Ligand NameSHH
EC.Number E.C.3.5.1.98
Resolution 1.85(Å)
Affinity (Kd/Ki/IC50)Kd=0.182uM
Release Year2013
Protein/NA SequenceCheck fasta file
Primary Reference (2013) J.Biol.Chem. Vol. 288: pp. 26926-26943
Ligand Properties
Formula C14H20N2O3
Molecular Weight 264.320
Exact Mass 264.147
No. of atoms 39
No. of bonds 39
Polar Surface Area 78.43
LOGP Value 1.59      (Computed with XLOGP3)
2.94      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 11
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q92769  
Entrez Gene IDNCBI Entrez Gene ID: 3066  
ASDInformation of known allosteric effects of PDB entries
 
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