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Related entries of code: 4olh
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4bb9RCSB PDB    PDBbind633aa, >4BB9_1|Chain... at 98%
4ly9RCSB PDB    PDBbind637aa, >4LY9_1|Chains... at 100%
4mquRCSB PDB    PDBbind636aa, >4MQU_1|Chains... at 99%
4mroRCSB PDB    PDBbind636aa, >4MRO_1|Chains... at 99%
4msuRCSB PDB    PDBbind636aa, >4MSU_1|Chains... at 99%
4ohkRCSB PDB    PDBbind638aa, >4OHK_1|Chains... *
4ohmRCSB PDB    PDBbind638aa, >4OHM_1|Chains... at 100%
4ohoRCSB PDB    PDBbind638aa, >4OHO_1|Chains... at 100%
4ohpRCSB PDB    PDBbind638aa, >4OHP_1|Chains... at 100%
4op1RCSB PDB    PDBbind638aa, >4OP1_1|Chains... at 100%
4op2RCSB PDB    PDBbind638aa, >4OP2_1|Chains... at 100%
4op3RCSB PDB    PDBbind638aa, >4OP3_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4olh
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameGlucokinase Regulatory Protein hGKRP
Ligand Name2TO
EC.Number E.C.-.-.-.-
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)IC50=5nM
Release Year2014
Protein/NA SequenceCheck fasta file
Primary Reference (2014) J.Med.Chem. Vol. 57: pp. 5949-5964
Ligand Properties
Formula C22H20F6N6O3S
Molecular Weight 562.488
Exact Mass 562.122
No. of atoms 58
No. of bonds 61
Polar Surface Area 133.92
LOGP Value 2.26      (Computed with XLOGP3)
4.61      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 6
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q14397  
Entrez Gene IDNCBI Entrez Gene ID: 2646  
ASDInformation of known allosteric effects of PDB entries
 
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