Browse entries in the PDBbind-CN Database
HEADER HYDROLASE/TRANSCRIPTION 04-MAR-14 4PQT TITLE INSIGHTS INTO THE MECHANISM OF DEUBIQUITINATION BY JAMM TITLE 2 DEUBIQUITINASES FROM CO-CRYSTAL STRUCTURES OF ENZYME WITH SUBSTRATE TITLE 3 AND PRODUCT COMPND MOL_ID: 1; COMPND 2 MOLECULE: AMSH-LIKE PROTEASE SST2; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: CATALYTIC DOMAIN UNP RESIDUES 245-435; COMPND 5 SYNONYM: SUPPRESSOR OF STE12 DELETION PROTEIN 2; COMPND 6 EC: 3.4.19.-; COMPND 7 ENGINEERED: YES; COMPND 8 MUTATION: YES; COMPND 9 MOL_ID: 2; COMPND 10 MOLECULE: PROTEIN UBBP4; COMPND 11 CHAIN: B; COMPND 12 FRAGMENT: UNP RESIDUES 77-152; COMPND 13 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE; SOURCE 3 ORGANISM_COMMON: FISSION YEAST; SOURCE 4 ORGANISM_TAXID: 284812; SOURCE 5 STRAIN: 972 / ATCC 24843; SOURCE 6 GENE: SPAC19B12.10, SST2; SOURCE 7 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 8 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 9 EXPRESSION_SYSTEM_STRAIN: ROSETTA; SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PGEX-6-P1; SOURCE 12 MOL_ID: 2; SOURCE 13 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 14 ORGANISM_COMMON: HUMAN; SOURCE 15 ORGANISM_TAXID: 9606; SOURCE 16 GENE: UBBP4, UBIQUITIN; SOURCE 17 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 18 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 19 EXPRESSION_SYSTEM_STRAIN: ROSETTA; SOURCE 20 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 21 EXPRESSION_SYSTEM_PLASMID: PET26B KEYWDS HELIX-BETA-HELIX SANDWICH, UBIQUITIN, DEUBIQUITINATION, ZINC KEYWDS 2 METALLOPROTEASE, LYSINE 63-LINKED POLYUBIQUITIN, HYDROLASE- KEYWDS 3 TRANSCRIPTION COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR R.K.SHRESTHA,J.A.RONAU,C.DAS REVDAT 1 18-JUN-14 4PQT 0 JRNL AUTH R.K.SHRESTHA,J.A.RONAU,C.W.DAVIES,R.G.GUENETTE,E.R.STRIETER, JRNL AUTH 2 L.N.PAUL,C.DAS JRNL TITL INSIGHTS INTO THE MECHANISM OF DEUBIQUITINATION BY JAMM JRNL TITL 2 DEUBIQUITINASES FROM COCRYSTAL STRUCTURES OF THE ENZYME WITH JRNL TITL 3 THE SUBSTRATE AND PRODUCT. JRNL REF BIOCHEMISTRY V. 53 3199 2014 JRNL REFN ISSN 0006-2960 JRNL PMID 24787148 JRNL DOI 10.1021/BI5003162 REMARK 2 REMARK 2 RESOLUTION. 2.05 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (PHENIX.REFINE: 1.8.4_1496) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE- REMARK 3 : KUNSTLEVE,LI-WEI HUNG,ROBERT IMMORMINO, REMARK 3 : TOM IOERGER,AIRLIE MCCOY,ERIK MCKEE,NIGEL REMARK 3 : MORIARTY,REETAL PAI,RANDY READ,JANE REMARK 3 : RICHARDSON,DAVID RICHARDSON,TOD ROMO,JIM REMARK 3 : SACCHETTINI,NICHOLAS SAUTER,JACOB SMITH, REMARK 3 : LAURENT STORONI,TOM TERWILLIGER,PETER REMARK 3 : ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.05 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 40.11 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.360 REMARK 3 COMPLETENESS FOR RANGE (%) : 99.7 REMARK 3 NUMBER OF REFLECTIONS : 16420 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.204 REMARK 3 R VALUE (WORKING SET) : 0.202 REMARK 3 FREE R VALUE : 0.253 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.070 REMARK 3 FREE R VALUE TEST SET COUNT : 832 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 40.1165 - 3.7134 1.00 2638 159 0.1476 0.1815 REMARK 3 2 3.7134 - 2.9477 1.00 2599 139 0.1956 0.2691 REMARK 3 3 2.9477 - 2.5752 1.00 2607 132 0.2389 0.3364 REMARK 3 4 2.5752 - 2.3398 1.00 2592 135 0.2506 0.2946 REMARK 3 5 2.3398 - 2.1721 1.00 2605 127 0.2575 0.2855 REMARK 3 6 2.1721 - 2.0440 0.98 2547 140 0.2857 0.3281 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.300 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 27.590 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.008 2090 REMARK 3 ANGLE : 1.213 2824 REMARK 3 CHIRALITY : 0.045 333 REMARK 3 PLANARITY : 0.007 358 REMARK 3 DIHEDRAL : 14.090 782 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 4PQT COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 06-MAR-14. REMARK 100 THE RCSB ID CODE IS RCSB085107. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 09-NOV-13 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 7 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 23-ID-D REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.033 REMARK 200 MONOCHROMATOR : SI 111 CHANNEL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : AREA DETECTOR REMARK 200 DETECTOR MANUFACTURER : MAR SCANNER 300 MM PLATE REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-3000 REMARK 200 DATA SCALING SOFTWARE : HKL-3000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 16438 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.050 REMARK 200 RESOLUTION RANGE LOW (A) : 60.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 200 DATA REDUNDANCY : 3.800 REMARK 200 R MERGE (I) : 0.08600 REMARK 200 R SYM (I) : 0.08600 REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 16.8000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.05 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.05 REMARK 200 COMPLETENESS FOR SHELL (%) : 100.0 REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : 0.62500 REMARK 200 R SYM FOR SHELL (I) : 0.62500 REMARK 200 <I/SIGMA(I)> FOR SHELL : 2.600 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: MOLREP REMARK 200 STARTING MODEL: PDB ENTRY 4K1R REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 41.80 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.11 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 1% W/V TRYPTONE, 0.05M HEPES SODIUM, REMARK 280 20% PEG 3,350, PH 7, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE REMARK 280 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 21 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 29.00150 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1, 2, 3 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 REMARK 350 BIOMOLECULE: 2 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 350 REMARK 350 BIOMOLECULE: 3 REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2930 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11940 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -11.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 239 REMARK 465 PRO A 240 REMARK 465 LEU A 241 REMARK 465 GLY A 242 REMARK 465 SER A 243 REMARK 465 MET A 244 REMARK 465 ALA A 245 REMARK 465 GLY A 246 REMARK 465 THR A 247 REMARK 465 PHE A 248 REMARK 465 VAL A 434 REMARK 465 LYS A 435 REMARK 465 GLY B -4 REMARK 465 PRO B -3 REMARK 465 LEU B -2 REMARK 465 GLY B -1 REMARK 465 SER B 0 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 LEU A 268 CG CD1 CD2 REMARK 470 LYS A 278 CG CD CE NZ REMARK 470 LYS A 282 CG CD CE NZ REMARK 470 LYS A 283 CG CD CE NZ REMARK 470 PRO A 417 CG CD REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O ASN A 298 O HOH A 637 2.11 REMARK 500 OE1 GLU A 422 O HOH A 639 2.16 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 PRO A 417 N - CA - CB ANGL. DEV. = 7.4 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 THR A 313 -166.03 -129.47 REMARK 500 ASP A 321 78.79 -151.82 REMARK 500 PRO A 417 33.57 -97.93 REMARK 500 ILE A 423 -168.01 -115.49 REMARK 500 ASN A 424 64.20 -118.64 REMARK 500 GLU B 64 13.75 59.77 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 501 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HIS A 406 NE2 REMARK 620 2 HIS A 404 NE2 101.4 REMARK 620 3 HIS A 356 NE2 111.9 112.8 REMARK 620 4 CYS A 397 SG 106.9 115.1 108.5 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN A 501 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE EDO A 503 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE EDO B 101 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 2ZNV RELATED DB: PDB REMARK 900 AMSH-LP E292A BOUND TO LYS63-LINKED UBIQUITIN DIMER REMARK 900 RELATED ID: 4K1R RELATED DB: PDB REMARK 900 CRYSTAL STRUCTURE OF SCHIZOSACCHAROMYCES POMBE SST2 REMARK 900 CATALYTIC DOMAIN AND UBIQUITIN DBREF 4PQT A 245 435 UNP Q9P371 SST2_SCHPO 245 435 DBREF 4PQT B 1 76 UNP J3QRK5 J3QRK5_HUMAN 77 152 SEQADV 4PQT GLY A 239 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT PRO A 240 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT LEU A 241 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT GLY A 242 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT SER A 243 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT MET A 244 UNP Q9P371 EXPRESSION TAG SEQADV 4PQT ALA A 354 UNP Q9P371 ASP 354 ENGINEERED MUTATION SEQADV 4PQT GLY B -4 UNP J3QRK5 EXPRESSION TAG SEQADV 4PQT PRO B -3 UNP J3QRK5 EXPRESSION TAG SEQADV 4PQT LEU B -2 UNP J3QRK5 EXPRESSION TAG SEQADV 4PQT GLY B -1 UNP J3QRK5 EXPRESSION TAG SEQADV 4PQT SER B 0 UNP J3QRK5 EXPRESSION TAG SEQADV 4PQT THR B 55 UNP J3QRK5 SER 131 CONFLICT SEQRES 1 A 197 GLY PRO LEU GLY SER MET ALA GLY THR PHE LYS ILE HIS SEQRES 2 A 197 ALA TYR THR GLU GLY GLY LYS PRO LEU ARG THR ILE TYR SEQRES 3 A 197 LEU PRO LYS LEU LEU LYS LYS VAL PHE LEU ASP VAL VAL SEQRES 4 A 197 LYS PRO ASN THR LYS LYS ASN LEU GLU THR CYS GLY ILE SEQRES 5 A 197 LEU CYS GLY LYS LEU ARG GLN ASN ALA PHE PHE ILE THR SEQRES 6 A 197 HIS LEU VAL ILE PRO LEU GLN GLU ALA THR SER ASP THR SEQRES 7 A 197 CYS GLY THR THR ASP GLU ALA SER LEU PHE GLU PHE GLN SEQRES 8 A 197 ASP LYS HIS ASN LEU LEU THR LEU GLY TRP ILE HIS THR SEQRES 9 A 197 HIS PRO THR GLN THR CYS PHE MET SER SER VAL ALA LEU SEQRES 10 A 197 HIS THR HIS CYS SER TYR GLN LEU MET LEU PRO GLU ALA SEQRES 11 A 197 ILE ALA ILE VAL MET ALA PRO SER LYS ASN THR SER GLY SEQRES 12 A 197 ILE PHE ARG LEU LEU ASP PRO GLU GLY LEU GLN THR ILE SEQRES 13 A 197 VAL LYS CYS ARG LYS PRO GLY LEU PHE HIS PRO HIS GLU SEQRES 14 A 197 GLY LYS VAL TYR THR MET VAL ALA GLN PRO GLY HIS VAL SEQRES 15 A 197 ARG GLU ILE ASN SER LYS LEU GLN VAL VAL ASP LEU ARG SEQRES 16 A 197 VAL LYS SEQRES 1 B 81 GLY PRO LEU GLY SER MET GLN ILE PHE VAL LYS THR LEU SEQRES 2 B 81 THR GLY LYS THR ILE THR LEU GLU VAL GLU PRO SER ASP SEQRES 3 B 81 THR ILE GLU ASN VAL LYS ALA LYS ILE GLN ASP LYS GLU SEQRES 4 B 81 GLY ILE PRO PRO ASP GLN GLN ARG LEU ILE PHE ALA GLY SEQRES 5 B 81 LYS GLN LEU GLU ASP GLY ARG THR LEU SER ASP TYR ASN SEQRES 6 B 81 ILE GLN LYS GLU SER THR LEU HIS LEU VAL LEU ARG LEU SEQRES 7 B 81 ARG GLY GLY HET ZN A 501 1 HET EDO A 502 4 HET EDO A 503 4 HET EDO B 101 4 HETNAM ZN ZINC ION HETNAM EDO 1,2-ETHANEDIOL HETSYN EDO ETHYLENE GLYCOL FORMUL 3 ZN ZN 2+ FORMUL 4 EDO 3(C2 H6 O2) FORMUL 7 HOH *78(H2 O) HELIX 1 1 LYS A 267 LYS A 283 1 17 HELIX 2 2 ASP A 321 HIS A 332 1 12 HELIX 3 3 SER A 351 LEU A 365 1 15 HELIX 4 4 PRO A 388 CYS A 397 1 10 HELIX 5 5 THR B 22 GLY B 35 1 14 HELIX 6 6 PRO B 37 ASP B 39 5 3 SHEET 1 A 2 ALA A 252 TYR A 253 0 SHEET 2 A 2 PRO A 259 LEU A 260 -1 O LEU A 260 N ALA A 252 SHEET 1 B 8 TYR A 411 MET A 413 0 SHEET 2 B 8 THR A 379 LEU A 385 -1 N ARG A 384 O THR A 412 SHEET 3 B 8 ILE A 369 ALA A 374 -1 N ALA A 370 O PHE A 383 SHEET 4 B 8 LEU A 335 THR A 342 1 N TRP A 339 O ILE A 371 SHEET 5 B 8 CYS A 288 ARG A 296 -1 N LEU A 291 O LEU A 337 SHEET 6 B 8 ALA A 299 ILE A 307 -1 O VAL A 306 N ILE A 290 SHEET 7 B 8 THR A 262 PRO A 266 1 N TYR A 264 O PHE A 300 SHEET 8 B 8 VAL A 420 ILE A 423 1 O ILE A 423 N LEU A 265 SHEET 1 C 7 TYR A 411 MET A 413 0 SHEET 2 C 7 THR A 379 LEU A 385 -1 N ARG A 384 O THR A 412 SHEET 3 C 7 ILE A 369 ALA A 374 -1 N ALA A 370 O PHE A 383 SHEET 4 C 7 LEU A 335 THR A 342 1 N TRP A 339 O ILE A 371 SHEET 5 C 7 CYS A 288 ARG A 296 -1 N LEU A 291 O LEU A 337 SHEET 6 C 7 ALA A 299 ILE A 307 -1 O VAL A 306 N ILE A 290 SHEET 7 C 7 GLN A 428 ASP A 431 1 O VAL A 430 N ILE A 307 SHEET 1 D 3 GLN A 310 ALA A 312 0 SHEET 2 D 3 CYS A 317 THR A 319 -1 O GLY A 318 N GLU A 311 SHEET 3 D 3 ARG B 74 GLY B 75 -1 O GLY B 75 N CYS A 317 SHEET 1 E 5 THR B 12 GLU B 16 0 SHEET 2 E 5 GLN B 2 LYS B 6 -1 N VAL B 5 O ILE B 13 SHEET 3 E 5 THR B 66 LEU B 71 1 O LEU B 67 N PHE B 4 SHEET 4 E 5 GLN B 41 PHE B 45 -1 N ILE B 44 O HIS B 68 SHEET 5 E 5 LYS B 48 GLN B 49 -1 O LYS B 48 N PHE B 45 LINK NE2 HIS A 406 ZN ZN A 501 1555 1555 1.84 LINK NE2 HIS A 404 ZN ZN A 501 1555 1555 2.05 LINK NE2 HIS A 356 ZN ZN A 501 1555 1555 2.13 LINK SG CYS A 397 ZN ZN A 501 1555 1555 2.32 CISPEP 1 ASP A 387 PRO A 388 0 13.28 CISPEP 2 GLN A 416 PRO A 417 0 2.90 SITE 1 AC1 4 HIS A 356 CYS A 397 HIS A 404 HIS A 406 SITE 1 AC2 4 GLN A 416 PRO A 417 GLY A 418 HOH A 608 SITE 1 AC3 7 HOH A 612 THR B 7 LEU B 8 LEU B 69 SITE 2 AC3 7 VAL B 70 LEU B 71 HOH B 207 CRYST1 42.413 58.003 56.189 90.00 108.97 90.00 P 1 21 1 2 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.023578 0.000000 0.008106 0.00000 SCALE2 0.000000 0.017240 0.000000 0.00000 SCALE3 0.000000 0.000000 0.018820 0.00000 ATOM 1 N LYS A 249 2.137 9.718 35.119 1.00 43.14 N ATOM 2 CA LYS A 249 3.511 9.934 35.556 1.00 39.26 C ATOM 3 C LYS A 249 4.321 10.652 34.480 1.00 49.10 C ATOM 4 O LYS A 249 4.970 11.668 34.754 1.00 44.65 O ATOM 5 CB LYS A 249 4.184 8.608 35.911 1.00 39.15 C ATOM 6 CG LYS A 249 5.536 8.759 36.609 1.00 39.30 C ATOM 7 CD LYS A 249 5.393 9.583 37.877 1.00 42.14 C ATOM 8 CE LYS A 249 6.612 9.479 38.789 1.00 46.02 C ATOM 9 NZ LYS A 249 7.806 10.192 38.255 1.00 48.01 N ATOM 10 N ILE A 250 4.280 10.121 33.256 1.00 45.06 N ATOM 11 CA ILE A 250 5.111 10.638 32.170 1.00 48.91 C ATOM 12 C ILE A 250 4.422 10.751 30.797 1.00 50.88 C ATOM 13 O ILE A 250 3.928 9.762 30.238 1.00 51.70 O ATOM 14 CB ILE A 250 6.354 9.777 31.982 1.00 44.48 C ATOM 15 CG1 ILE A 250 7.305 9.933 33.176 1.00 42.03 C ATOM 16 CG2 ILE A 250 7.032 10.179 30.717 1.00 40.81 C ATOM 17 CD1 ILE A 250 8.249 11.096 33.072 1.00 37.42 C ATOM 18 N HIS A 251 4.406 11.972 30.266 1.00 47.48 N ATOM 19 CA HIS A 251 4.003 12.233 28.890 1.00 46.05 C ATOM 20 C HIS A 251 5.179 12.835 28.123 1.00 48.13 C ATOM 21 O HIS A 251 5.592 13.950 28.435 1.00 42.49 O ATOM 22 CB HIS A 251 2.825 13.212 28.818 1.00 45.52 C ATOM 23 CG HIS A 251 1.705 12.909 29.763 1.00 55.62 C ATOM 24 ND1 HIS A 251 1.347 11.625 30.117 1.00 60.02 N ATOM 25 CD2 HIS A 251 0.846 13.732 30.411 1.00 54.65 C ATOM 26 CE1 HIS A 251 0.323 11.672 30.951 1.00 61.43 C ATOM 27 NE2 HIS A 251 -0.001 12.938 31.145 1.00 57.53 N ATOM 28 N ALA A 252 5.712 12.125 27.126 1.00 46.12 N ATOM 29 CA ALA A 252 6.741 12.709 26.259 1.00 39.48 C ATOM 30 C ALA A 252 6.114 13.169 24.947 1.00 34.86 C ATOM 31 O ALA A 252 5.108 12.615 24.494 1.00 35.82 O ATOM 32 CB ALA A 252 7.876 11.724 26.001 1.00 35.03 C ATOM 33 N TYR A 253 6.700 14.208 24.357 1.00 39.34 N ATOM 34 CA TYR A 253 6.167 14.816 23.138 1.00 32.14 C ATOM 35 C TYR A 253 7.288 15.113 22.151 1.00 30.06 C ATOM 36 O TYR A 253 8.424 15.395 22.543 1.00 27.95 O ATOM 37 CB TYR A 253 5.405 16.116 23.448 1.00 36.21 C ATOM 38 CG TYR A 253 4.148 15.935 24.281 1.00 34.88 C ATOM 39 CD1 TYR A 253 4.188 15.982 25.679 1.00 35.18 C ATOM 40 CD2 TYR A 253 2.923 15.712 23.670 1.00 34.96 C ATOM 41 CE1 TYR A 253 3.019 15.810 26.446 1.00 36.47 C ATOM 42 CE2 TYR A 253 1.758 15.539 24.424 1.00 38.37 C ATOM 43 CZ TYR A 253 1.808 15.588 25.806 1.00 38.22 C ATOM 44 OH TYR A 253 0.636 15.415 26.529 1.00 36.37 O ATOM 45 N THR A 254 6.957 15.041 20.868 1.00 29.90 N ATOM 46 CA THR A 254 7.893 15.426 19.815 1.00 32.95 C ATOM 47 C THR A 254 8.056 16.933 19.752 1.00 33.33 C ATOM 48 O THR A 254 7.444 17.677 20.519 1.00 26.61 O ATOM 49 CB THR A 254 7.440 14.941 18.451 1.00 25.33 C ATOM 50 OG1 THR A 254 6.215 15.600 18.096 1.00 28.15 O ATOM 51 CG2 THR A 254 7.226 13.440 18.482 1.00 24.26 C ATOM 52 N GLU A 255 8.897 17.373 18.829 1.00 32.71 N ATOM 53 CA GLU A 255 9.115 18.793 18.615 1.00 33.23 C ATOM 54 C GLU A 255 7.839 19.439 18.064 1.00 31.50 C ATOM 55 O GLU A 255 7.546 20.593 18.362 1.00 36.09 O ATOM 56 CB GLU A 255 10.301 19.005 17.671 1.00 27.27 C ATOM 57 CG GLU A 255 11.656 18.669 18.292 1.00 24.96 C ATOM 58 CD GLU A 255 11.913 17.173 18.448 1.00 27.82 C ATOM 59 OE1 GLU A 255 11.162 16.345 17.876 1.00 24.70 O ATOM 60 OE2 GLU A 255 12.880 16.821 19.159 1.00 26.13 O ATOM 61 N GLY A 256 7.083 18.675 17.277 1.00 30.50 N ATOM 62 CA GLY A 256 5.817 19.126 16.720 1.00 32.36 C ATOM 63 C GLY A 256 4.593 18.947 17.618 1.00 34.45 C ATOM 64 O GLY A 256 3.458 19.198 17.197 1.00 43.59 O ATOM 65 N GLY A 257 4.816 18.491 18.844 1.00 36.10 N ATOM 66 CA GLY A 257 3.746 18.372 19.813 1.00 38.76 C ATOM 67 C GLY A 257 2.950 17.078 19.804 1.00 39.13 C ATOM 68 O GLY A 257 1.915 16.993 20.470 1.00 38.31 O ATOM 69 N LYS A 258 3.409 16.072 19.061 1.00 36.55 N ATOM 70 CA LYS A 258 2.723 14.778 19.060 1.00 35.63 C ATOM 71 C LYS A 258 3.203 13.945 20.243 1.00 33.82 C ATOM 72 O LYS A 258 4.380 14.002 20.617 1.00 31.83 O ATOM 73 CB LYS A 258 2.941 14.020 17.744 1.00 35.41 C ATOM 74 CG LYS A 258 2.592 14.817 16.466 1.00 42.75 C ATOM 75 CD LYS A 258 1.088 15.055 16.288 1.00 43.34 C ATOM 76 CE LYS A 258 0.794 15.917 15.058 1.00 39.27 C ATOM 77 NZ LYS A 258 1.283 15.313 13.770 1.00 40.16 N ATOM 78 N PRO A 259 2.280 13.181 20.852 1.00 37.34 N ATOM 79 CA PRO A 259 2.574 12.389 22.046 1.00 35.60 C ATOM 80 C PRO A 259 3.350 11.135 21.689 1.00 29.42 C ATOM 81 O PRO A 259 3.125 10.558 20.627 1.00 30.56 O ATOM 82 CB PRO A 259 1.184 12.045 22.582 1.00 36.54 C ATOM 83 CG PRO A 259 0.369 11.910 21.355 1.00 40.10 C ATOM 84 CD PRO A 259 0.895 12.974 20.401 1.00 34.05 C ATOM 85 N LEU A 260 4.271 10.736 22.553 1.00 30.74 N ATOM 86 CA LEU A 260 5.051 9.537 22.309 1.00 28.02 C ATOM 87 C LEU A 260 4.709 8.489 23.348 1.00 30.73 C ATOM 88 O LEU A 260 4.845 8.728 24.546 1.00 30.59 O ATOM 89 CB LEU A 260 6.547 9.844 22.344 1.00 25.01 C ATOM 90 CG LEU A 260 7.045 10.841 21.302 1.00 26.50 C ATOM 91 CD1 LEU A 260 8.375 11.413 21.745 1.00 25.97 C ATOM 92 CD2 LEU A 260 7.174 10.185 19.923 1.00 20.93 C ATOM 93 N ARG A 261 4.275 7.320 22.901 1.00 25.43 N ATOM 94 CA ARG A 261 4.058 6.237 23.842 1.00 27.58 C ATOM 95 C ARG A 261 5.401 5.783 24.424 1.00 27.80 C ATOM 96 O ARG A 261 6.448 5.911 23.780 1.00 28.86 O ATOM 97 CB ARG A 261 3.324 5.086 23.173 1.00 21.60 C ATOM 98 CG ARG A 261 1.888 5.428 22.844 1.00 27.30 C ATOM 99 CD ARG A 261 1.329 4.516 21.778 1.00 29.91 C ATOM 100 NE ARG A 261 2.046 4.714 20.520 1.00 31.62 N ATOM 101 CZ ARG A 261 1.798 4.038 19.406 1.00 27.11 C ATOM 102 NH1 ARG A 261 0.849 3.113 19.397 1.00 27.86 N ATOM 103 NH2 ARG A 261 2.500 4.288 18.303 1.00 22.67 N ATOM 104 N THR A 262 5.370 5.286 25.659 1.00 26.96 N ATOM 105 CA THR A 262 6.572 4.814 26.337 1.00 29.24 C ATOM 106 C THR A 262 7.100 3.523 25.705 1.00 26.30 C ATOM 107 O THR A 262 6.320 2.675 25.280 1.00 23.34 O ATOM 108 CB THR A 262 6.308 4.569 27.834 1.00 28.97 C ATOM 109 OG1 THR A 262 5.787 5.768 28.430 1.00 30.98 O ATOM 110 CG2 THR A 262 7.581 4.187 28.533 1.00 25.04 C ATOM 111 N ILE A 263 8.424 3.414 25.609 1.00 20.81 N ATOM 112 CA ILE A 263 9.100 2.173 25.261 1.00 23.26 C ATOM 113 C ILE A 263 9.863 1.677 26.480 1.00 25.67 C ATOM 114 O ILE A 263 10.699 2.401 27.024 1.00 23.19 O ATOM 115 CB ILE A 263 10.103 2.351 24.086 1.00 24.19 C ATOM 116 CG1 ILE A 263 9.366 2.506 22.754 1.00 25.46 C ATOM 117 CG2 ILE A 263 11.127 1.179 24.058 1.00 20.95 C ATOM 118 CD1 ILE A 263 10.274 2.877 21.567 1.00 19.04 C ATOM 119 N TYR A 264 9.580 0.453 26.921 1.00 27.51 N ATOM 120 CA TYR A 264 10.353 -0.137 28.013 1.00 24.85 C ATOM 121 C TYR A 264 11.515 -0.984 27.481 1.00 26.06 C ATOM 122 O TYR A 264 11.309 -1.983 26.808 1.00 26.88 O ATOM 123 CB TYR A 264 9.450 -0.974 28.912 1.00 25.03 C ATOM 124 CG TYR A 264 8.441 -0.145 29.659 1.00 28.90 C ATOM 125 CD1 TYR A 264 8.789 0.508 30.843 1.00 35.42 C ATOM 126 CD2 TYR A 264 7.147 0.007 29.181 1.00 26.31 C ATOM 127 CE1 TYR A 264 7.867 1.297 31.534 1.00 32.48 C ATOM 128 CE2 TYR A 264 6.213 0.790 29.869 1.00 35.87 C ATOM 129 CZ TYR A 264 6.583 1.425 31.049 1.00 34.94 C ATOM 130 OH TYR A 264 5.673 2.197 31.733 1.00 43.28 O ATOM 131 N LEU A 265 12.734 -0.571 27.804 1.00 28.70 N ATOM 132 CA LEU A 265 13.941 -1.229 27.326 1.00 24.70 C ATOM 133 C LEU A 265 14.589 -1.995 28.471 1.00 31.87 C ATOM 134 O LEU A 265 14.770 -1.445 29.554 1.00 26.56 O ATOM 135 CB LEU A 265 14.907 -0.192 26.756 1.00 25.64 C ATOM 136 CG LEU A 265 16.359 -0.535 26.456 1.00 24.68 C ATOM 137 CD1 LEU A 265 16.449 -1.343 25.143 1.00 23.39 C ATOM 138 CD2 LEU A 265 17.151 0.764 26.356 1.00 24.19 C ATOM 139 N PRO A 266 14.895 -3.284 28.253 1.00 26.92 N ATOM 140 CA PRO A 266 15.640 -4.068 29.245 1.00 28.95 C ATOM 141 C PRO A 266 17.021 -3.496 29.515 1.00 32.29 C ATOM 142 O PRO A 266 17.806 -3.331 28.570 1.00 31.65 O ATOM 143 CB PRO A 266 15.737 -5.457 28.587 1.00 26.90 C ATOM 144 CG PRO A 266 14.472 -5.543 27.756 1.00 29.72 C ATOM 145 CD PRO A 266 14.201 -4.135 27.265 1.00 24.49 C ATOM 146 N LYS A 267 17.332 -3.210 30.781 1.00 34.09 N ATOM 147 CA LYS A 267 18.657 -2.664 31.126 1.00 30.04 C ATOM 148 C LYS A 267 19.826 -3.547 30.672 1.00 32.36 C ATOM 149 O LYS A 267 20.915 -3.054 30.340 1.00 33.71 O ATOM 150 CB LYS A 267 18.769 -2.406 32.639 1.00 43.94 C ATOM 151 CG LYS A 267 17.948 -1.215 33.143 1.00 39.27 C ATOM 152 CD LYS A 267 17.759 -1.257 34.659 1.00 53.09 C ATOM 153 CE LYS A 267 17.908 0.136 35.314 1.00 59.14 C ATOM 154 NZ LYS A 267 16.813 0.406 36.310 1.00 51.95 N ATOM 155 N LEU A 268 19.585 -4.846 30.615 1.00 28.11 N ATOM 156 CA LEU A 268 20.603 -5.782 30.174 1.00 31.53 C ATOM 157 C LEU A 268 20.919 -5.680 28.671 1.00 31.49 C ATOM 158 O LEU A 268 22.025 -6.041 28.248 1.00 35.18 O ATOM 159 CB LEU A 268 20.178 -7.209 30.535 1.00 29.57 C ATOM 160 N LEU A 269 19.974 -5.189 27.866 1.00 31.83 N ATOM 161 CA LEU A 269 20.101 -5.258 26.396 1.00 24.82 C ATOM 162 C LEU A 269 21.422 -4.720 25.863 1.00 29.74 C ATOM 163 O LEU A 269 22.138 -5.420 25.139 1.00 29.91 O ATOM 164 CB LEU A 269 18.960 -4.502 25.721 1.00 28.05 C ATOM 165 CG LEU A 269 18.880 -4.726 24.201 1.00 27.94 C ATOM 166 CD1 LEU A 269 17.441 -4.825 23.769 1.00 23.73 C ATOM 167 CD2 LEU A 269 19.592 -3.637 23.407 1.00 23.23 C ATOM 168 N LYS A 270 21.731 -3.471 26.206 1.00 26.75 N ATOM 169 CA LYS A 270 22.952 -2.840 25.719 1.00 28.00 C ATOM 170 C LYS A 270 24.142 -3.729 26.001 1.00 28.22 C ATOM 171 O LYS A 270 24.922 -4.038 25.095 1.00 30.29 O ATOM 172 CB LYS A 270 23.165 -1.472 26.366 1.00 32.03 C ATOM 173 CG LYS A 270 22.415 -0.307 25.721 1.00 29.30 C ATOM 174 CD LYS A 270 22.552 0.914 26.637 1.00 33.16 C ATOM 175 CE LYS A 270 21.791 2.111 26.123 1.00 38.15 C ATOM 176 NZ LYS A 270 22.289 3.356 26.777 1.00 43.55 N ATOM 177 N LYS A 271 24.249 -4.163 27.258 1.00 31.99 N ATOM 178 CA LYS A 271 25.355 -5.011 27.706 1.00 37.38 C ATOM 179 C LYS A 271 25.387 -6.321 26.914 1.00 33.62 C ATOM 180 O LYS A 271 26.420 -6.709 26.347 1.00 33.94 O ATOM 181 CB LYS A 271 25.225 -5.294 29.209 1.00 37.40 C ATOM 182 CG LYS A 271 26.388 -6.071 29.814 1.00 41.65 C ATOM 183 CD LYS A 271 25.982 -6.752 31.125 1.00 42.81 C ATOM 184 CE LYS A 271 27.124 -7.575 31.703 1.00 44.05 C ATOM 185 NZ LYS A 271 27.690 -8.561 30.731 1.00 49.50 N ATOM 186 N VAL A 272 24.231 -6.970 26.855 1.00 31.43 N ATOM 187 CA VAL A 272 24.078 -8.245 26.165 1.00 32.06 C ATOM 188 C VAL A 272 24.384 -8.155 24.669 1.00 33.72 C ATOM 189 O VAL A 272 25.017 -9.042 24.108 1.00 32.22 O ATOM 190 CB VAL A 272 22.668 -8.774 26.371 1.00 34.05 C ATOM 191 CG1 VAL A 272 22.347 -9.860 25.364 1.00 36.13 C ATOM 192 CG2 VAL A 272 22.514 -9.269 27.818 1.00 34.66 C ATOM 193 N PHE A 273 23.950 -7.073 24.023 1.00 33.79 N ATOM 194 CA PHE A 273 24.271 -6.857 22.611 1.00 29.06 C ATOM 195 C PHE A 273 25.791 -6.789 22.401 1.00 31.14 C ATOM 196 O PHE A 273 26.325 -7.392 21.461 1.00 28.08 O ATOM 197 CB PHE A 273 23.595 -5.576 22.090 1.00 26.10 C ATOM 198 CG PHE A 273 24.003 -5.191 20.694 1.00 27.40 C ATOM 199 CD1 PHE A 273 23.499 -5.870 19.589 1.00 26.05 C ATOM 200 CD2 PHE A 273 24.875 -4.133 20.479 1.00 26.59 C ATOM 201 CE1 PHE A 273 23.865 -5.496 18.305 1.00 23.24 C ATOM 202 CE2 PHE A 273 25.248 -3.763 19.194 1.00 22.43 C ATOM 203 CZ PHE A 273 24.749 -4.447 18.112 1.00 23.68 C ATOM 204 N LEU A 274 26.482 -6.055 23.269 1.00 29.28 N ATOM 205 CA LEU A 274 27.931 -5.935 23.136 1.00 39.39 C ATOM 206 C LEU A 274 28.591 -7.307 23.312 1.00 35.03 C ATOM 207 O LEU A 274 29.497 -7.660 22.551 1.00 35.79 O ATOM 208 CB LEU A 274 28.502 -4.918 24.130 1.00 35.08 C ATOM 209 CG LEU A 274 28.322 -3.432 23.774 1.00 34.27 C ATOM 210 CD1 LEU A 274 28.980 -2.539 24.810 1.00 29.48 C ATOM 211 CD2 LEU A 274 28.838 -3.085 22.379 1.00 32.46 C ATOM 212 N ASP A 275 28.115 -8.072 24.296 1.00 37.77 N ATOM 213 CA ASP A 275 28.569 -9.452 24.506 1.00 41.94 C ATOM 214 C ASP A 275 28.475 -10.274 23.221 1.00 42.27 C ATOM 215 O ASP A 275 29.489 -10.713 22.677 1.00 42.09 O ATOM 216 CB ASP A 275 27.753 -10.146 25.609 1.00 42.56 C ATOM 217 CG ASP A 275 28.007 -9.558 26.999 1.00 48.32 C ATOM 218 OD1 ASP A 275 29.046 -8.885 27.182 1.00 49.69 O ATOM 219 OD2 ASP A 275 27.176 -9.783 27.916 1.00 40.91 O ATOM 220 N VAL A 276 27.252 -10.460 22.730 1.00 41.32 N ATOM 221 CA VAL A 276 27.023 -11.311 21.562 1.00 41.37 C ATOM 222 C VAL A 276 27.758 -10.861 20.291 1.00 39.18 C ATOM 223 O VAL A 276 28.084 -11.692 19.441 1.00 41.85 O ATOM 224 CB VAL A 276 25.522 -11.415 21.245 1.00 33.72 C ATOM 225 CG1 VAL A 276 25.267 -12.556 20.276 1.00 38.93 C ATOM 226 CG2 VAL A 276 24.745 -11.641 22.508 1.00 31.07 C ATOM 227 N VAL A 277 28.035 -9.569 20.147 1.00 34.83 N ATOM 228 CA VAL A 277 28.711 -9.110 18.929 1.00 36.40 C ATOM 229 C VAL A 277 30.203 -8.803 19.147 1.00 42.37 C ATOM 230 O VAL A 277 30.909 -8.394 18.212 1.00 44.97 O ATOM 231 CB VAL A 277 28.003 -7.869 18.338 1.00 38.78 C ATOM 232 CG1 VAL A 277 26.500 -8.117 18.280 1.00 31.73 C ATOM 233 CG2 VAL A 277 28.302 -6.615 19.159 1.00 32.40 C ATOM 234 N LYS A 278 30.674 -9.029 20.375 1.00 44.00 N ATOM 235 CA LYS A 278 32.073 -8.781 20.751 1.00 44.40 C ATOM 236 C LYS A 278 33.128 -9.309 19.768 1.00 41.30 C ATOM 237 O LYS A 278 34.119 -8.620 19.530 1.00 44.38 O ATOM 238 CB LYS A 278 32.343 -9.343 22.145 1.00 42.72 C ATOM 239 N PRO A 279 32.935 -10.518 19.194 1.00 40.28 N ATOM 240 CA PRO A 279 33.869 -10.967 18.147 1.00 40.26 C ATOM 241 C PRO A 279 34.066 -10.000 16.975 1.00 48.17 C ATOM 242 O PRO A 279 35.199 -9.812 16.517 1.00 50.80 O ATOM 243 CB PRO A 279 33.224 -12.259 17.650 1.00 40.61 C ATOM 244 CG PRO A 279 32.571 -12.802 18.835 1.00 36.38 C ATOM 245 CD PRO A 279 32.064 -11.624 19.631 1.00 35.24 C ATOM 246 N ASN A 280 32.985 -9.413 16.476 1.00 48.73 N ATOM 247 CA ASN A 280 33.103 -8.444 15.394 1.00 46.72 C ATOM 248 C ASN A 280 33.781 -7.173 15.870 1.00 42.45 C ATOM 249 O ASN A 280 34.557 -6.564 15.143 1.00 45.44 O ATOM 250 CB ASN A 280 31.731 -8.110 14.812 1.00 46.87 C ATOM 251 CG ASN A 280 31.083 -9.292 14.153 1.00 45.20 C ATOM 252 OD1 ASN A 280 31.760 -10.230 13.732 1.00 47.30 O ATOM 253 ND2 ASN A 280 29.759 -9.256 14.047 1.00 42.90 N ATOM 254 N THR A 281 33.471 -6.763 17.093 1.00 45.13 N ATOM 255 CA THR A 281 34.080 -5.564 17.627 1.00 47.36 C ATOM 256 C THR A 281 35.598 -5.780 17.691 1.00 55.09 C ATOM 257 O THR A 281 36.381 -4.887 17.348 1.00 52.57 O ATOM 258 CB THR A 281 33.528 -5.209 19.009 1.00 44.36 C ATOM 259 OG1 THR A 281 32.106 -5.397 19.024 1.00 42.68 O ATOM 260 CG2 THR A 281 33.856 -3.765 19.343 1.00 41.03 C ATOM 261 N LYS A 282 36.000 -6.983 18.104 1.00 55.05 N ATOM 262 CA LYS A 282 37.407 -7.362 18.130 1.00 48.08 C ATOM 263 C LYS A 282 38.031 -7.182 16.747 1.00 46.80 C ATOM 264 O LYS A 282 39.058 -6.513 16.608 1.00 48.52 O ATOM 265 CB LYS A 282 37.564 -8.795 18.616 1.00 46.59 C ATOM 266 N LYS A 283 37.385 -7.737 15.721 1.00 45.07 N ATOM 267 CA LYS A 283 37.896 -7.652 14.353 1.00 39.55 C ATOM 268 C LYS A 283 37.672 -6.268 13.737 1.00 45.61 C ATOM 269 O LYS A 283 37.798 -6.094 12.519 1.00 46.78 O ATOM 270 CB LYS A 283 37.254 -8.730 13.485 1.00 41.91 C ATOM 271 N ASN A 284 37.362 -5.294 14.592 1.00 44.78 N ATOM 272 CA ASN A 284 36.989 -3.945 14.178 1.00 47.23 C ATOM 273 C ASN A 284 35.968 -3.962 13.053 1.00 47.58 C ATOM 274 O ASN A 284 36.198 -3.391 11.986 1.00 45.84 O ATOM 275 CB ASN A 284 38.217 -3.143 13.754 1.00 51.16 C ATOM 276 CG ASN A 284 37.913 -1.675 13.581 1.00 48.79 C ATOM 277 OD1 ASN A 284 36.957 -1.159 14.160 1.00 49.13 O ATOM 278 ND2 ASN A 284 38.720 -0.991 12.780 1.00 49.34 N ATOM 279 N LEU A 285 34.857 -4.654 13.308 1.00 45.79 N ATOM 280 CA LEU A 285 33.698 -4.687 12.419 1.00 45.15 C ATOM 281 C LEU A 285 32.439 -4.287 13.194 1.00 41.94 C ATOM 282 O LEU A 285 32.201 -4.775 14.306 1.00 43.94 O ATOM 283 CB LEU A 285 33.513 -6.081 11.807 1.00 43.75 C ATOM 284 CG LEU A 285 34.551 -6.629 10.826 1.00 44.98 C ATOM 285 CD1 LEU A 285 34.551 -8.148 10.872 1.00 47.97 C ATOM 286 CD2 LEU A 285 34.295 -6.152 9.401 1.00 44.28 C ATOM 287 N GLU A 286 31.640 -3.401 12.605 1.00 42.82 N ATOM 288 CA GLU A 286 30.356 -3.005 13.187 1.00 36.16 C ATOM 289 C GLU A 286 29.357 -4.151 13.161 1.00 32.89 C ATOM 290 O GLU A 286 29.494 -5.079 12.375 1.00 35.04 O ATOM 291 CB GLU A 286 29.781 -1.794 12.444 1.00 35.52 C ATOM 292 CG GLU A 286 30.635 -0.540 12.585 1.00 39.33 C ATOM 293 CD GLU A 286 29.999 0.705 11.980 1.00 38.95 C ATOM 294 OE1 GLU A 286 28.957 0.590 11.300 1.00 36.49 O ATOM 295 OE2 GLU A 286 30.551 1.807 12.196 1.00 39.48 O ATOM 296 N THR A 287 28.352 -4.082 14.028 1.00 34.39 N ATOM 297 CA THR A 287 27.265 -5.065 14.036 1.00 32.01 C ATOM 298 C THR A 287 25.937 -4.361 14.284 1.00 29.41 C ATOM 299 O THR A 287 25.881 -3.392 15.029 1.00 26.09 O ATOM 300 CB THR A 287 27.461 -6.141 15.119 1.00 31.25 C ATOM 301 OG1 THR A 287 28.856 -6.456 15.248 1.00 35.00 O ATOM 302 CG2 THR A 287 26.650 -7.401 14.774 1.00 31.59 C ATOM 303 N CYS A 288 24.861 -4.841 13.681 1.00 25.45 N ATOM 304 CA CYS A 288 23.586 -4.195 13.935 1.00 22.25 C ATOM 305 C CYS A 288 22.568 -5.200 14.445 1.00 21.42 C ATOM 306 O CYS A 288 22.684 -6.395 14.200 1.00 22.19 O ATOM 307 CB CYS A 288 23.087 -3.493 12.673 1.00 21.86 C ATOM 308 SG CYS A 288 22.695 -4.585 11.306 1.00 29.51 S ATOM 309 N GLY A 289 21.585 -4.711 15.186 1.00 20.49 N ATOM 310 CA GLY A 289 20.539 -5.568 15.689 1.00 18.03 C ATOM 311 C GLY A 289 19.215 -4.851 15.574 1.00 18.09 C ATOM 312 O GLY A 289 19.177 -3.645 15.374 1.00 18.61 O ATOM 313 N ILE A 290 18.127 -5.592 15.709 1.00 16.33 N ATOM 314 CA ILE A 290 16.792 -5.006 15.673 1.00 15.72 C ATOM 315 C ILE A 290 16.178 -5.079 17.050 1.00 17.91 C ATOM 316 O ILE A 290 16.232 -6.136 17.681 1.00 21.07 O ATOM 317 CB ILE A 290 15.865 -5.746 14.710 1.00 17.18 C ATOM 318 CG1 ILE A 290 16.470 -5.819 13.302 1.00 21.63 C ATOM 319 CG2 ILE A 290 14.488 -5.078 14.682 1.00 17.12 C ATOM 320 CD1 ILE A 290 16.162 -4.571 12.467 1.00 31.60 C ATOM 321 N LEU A 291 15.580 -3.993 17.526 1.00 14.06 N ATOM 322 CA LEU A 291 14.829 -4.104 18.773 1.00 17.80 C ATOM 323 C LEU A 291 13.361 -4.445 18.451 1.00 16.71 C ATOM 324 O LEU A 291 12.658 -3.656 17.832 1.00 18.32 O ATOM 325 CB LEU A 291 14.924 -2.815 19.590 1.00 20.47 C ATOM 326 CG LEU A 291 16.262 -2.061 19.608 1.00 17.06 C ATOM 327 CD1 LEU A 291 16.048 -0.731 20.331 1.00 12.04 C ATOM 328 CD2 LEU A 291 17.393 -2.875 20.234 1.00 18.61 C ATOM 329 N CYS A 292 12.925 -5.626 18.882 1.00 19.94 N ATOM 330 CA CYS A 292 11.574 -6.141 18.645 1.00 21.06 C ATOM 331 C CYS A 292 10.758 -6.301 19.937 1.00 19.82 C ATOM 332 O CYS A 292 11.306 -6.619 20.995 1.00 17.45 O ATOM 333 CB CYS A 292 11.648 -7.502 17.942 1.00 17.13 C ATOM 334 SG CYS A 292 12.244 -7.411 16.262 1.00 22.93 S ATOM 335 N GLY A 293 9.448 -6.121 19.837 1.00 19.48 N ATOM 336 CA GLY A 293 8.589 -6.307 20.996 1.00 22.27 C ATOM 337 C GLY A 293 7.101 -6.202 20.730 1.00 22.81 C ATOM 338 O GLY A 293 6.620 -6.509 19.645 1.00 20.49 O ATOM 339 N LYS A 294 6.370 -5.762 21.750 1.00 28.80 N ATOM 340 CA LYS A 294 4.915 -5.818 21.749 1.00 26.83 C ATOM 341 C LYS A 294 4.315 -4.537 22.318 1.00 28.30 C ATOM 342 O LYS A 294 4.894 -3.908 23.210 1.00 27.33 O ATOM 343 CB LYS A 294 4.420 -7.015 22.585 1.00 33.62 C ATOM 344 CG LYS A 294 5.241 -8.299 22.454 1.00 30.08 C ATOM 345 CD LYS A 294 4.954 -8.981 21.131 1.00 34.81 C ATOM 346 CE LYS A 294 4.576 -10.450 21.346 1.00 34.34 C ATOM 347 NZ LYS A 294 3.982 -11.026 20.120 1.00 38.79 N ATOM 348 N LEU A 295 3.150 -4.168 21.808 1.00 22.13 N ATOM 349 CA LEU A 295 2.380 -3.075 22.380 1.00 31.21 C ATOM 350 C LEU A 295 1.348 -3.622 23.361 1.00 30.82 C ATOM 351 O LEU A 295 0.459 -4.381 22.978 1.00 30.60 O ATOM 352 CB LEU A 295 1.677 -2.262 21.295 1.00 22.99 C ATOM 353 CG LEU A 295 0.669 -1.216 21.783 1.00 24.13 C ATOM 354 CD1 LEU A 295 1.308 -0.120 22.622 1.00 25.97 C ATOM 355 CD2 LEU A 295 -0.031 -0.618 20.586 1.00 29.61 C ATOM 356 N ARG A 296 1.495 -3.250 24.627 1.00 31.38 N ATOM 357 CA ARG A 296 0.506 -3.580 25.632 1.00 32.73 C ATOM 358 C ARG A 296 0.092 -2.306 26.350 1.00 36.50 C ATOM 359 O ARG A 296 0.922 -1.632 26.974 1.00 35.44 O ATOM 360 CB ARG A 296 1.046 -4.620 26.616 1.00 36.53 C ATOM 361 CG ARG A 296 1.420 -5.944 25.934 1.00 43.54 C ATOM 362 CD ARG A 296 2.422 -6.760 26.761 1.00 46.70 C ATOM 363 NE ARG A 296 2.896 -7.966 26.070 1.00 56.85 N ATOM 364 CZ ARG A 296 4.160 -8.393 26.097 1.00 54.49 C ATOM 365 NH1 ARG A 296 5.080 -7.723 26.784 1.00 42.45 N ATOM 366 NH2 ARG A 296 4.508 -9.493 25.441 1.00 59.85 N ATOM 367 N GLN A 297 -1.192 -1.972 26.220 1.00 37.21 N ATOM 368 CA GLN A 297 -1.818 -0.878 26.963 1.00 39.14 C ATOM 369 C GLN A 297 -1.149 0.480 26.679 1.00 33.96 C ATOM 370 O GLN A 297 -0.627 1.138 27.588 1.00 33.19 O ATOM 371 CB GLN A 297 -1.777 -1.185 28.461 1.00 41.14 C ATOM 372 CG GLN A 297 -2.825 -2.192 29.005 1.00 48.44 C ATOM 373 CD GLN A 297 -4.298 -1.894 28.627 1.00 63.61 C ATOM 374 OE1 GLN A 297 -4.591 -1.012 27.809 1.00 64.04 O ATOM 375 NE2 GLN A 297 -5.234 -2.651 29.237 1.00 67.49 N ATOM 376 N ASN A 298 -1.046 0.809 25.395 1.00 32.69 N ATOM 377 CA ASN A 298 -0.502 2.093 24.963 1.00 34.64 C ATOM 378 C ASN A 298 0.962 2.302 25.366 1.00 35.71 C ATOM 379 O ASN A 298 1.435 3.439 25.409 1.00 38.29 O ATOM 380 CB ASN A 298 -1.368 3.238 25.500 1.00 31.57 C ATOM 381 CG ASN A 298 -1.469 4.392 24.525 1.00 38.83 C ATOM 382 OD1 ASN A 298 -1.706 4.204 23.323 1.00 40.24 O ATOM 383 ND2 ASN A 298 -1.278 5.598 25.036 1.00 45.28 N ATOM 384 N ALA A 299 1.670 1.204 25.655 1.00 29.38 N ATOM 385 CA ALA A 299 3.123 1.234 25.831 1.00 29.37 C ATOM 386 C ALA A 299 3.817 0.059 25.126 1.00 30.19 C ATOM 387 O ALA A 299 3.270 -1.045 25.026 1.00 26.59 O ATOM 388 CB ALA A 299 3.482 1.240 27.300 1.00 29.68 C ATOM 389 N PHE A 300 5.036 0.295 24.656 1.00 27.13 N ATOM 390 CA PHE A 300 5.809 -0.747 23.989 1.00 22.98 C ATOM 391 C PHE A 300 6.821 -1.391 24.935 1.00 23.73 C ATOM 392 O PHE A 300 7.465 -0.708 25.730 1.00 25.97 O ATOM 393 CB PHE A 300 6.541 -0.166 22.769 1.00 19.39 C ATOM 394 CG PHE A 300 5.631 0.363 21.695 1.00 22.39 C ATOM 395 CD1 PHE A 300 4.925 -0.507 20.870 1.00 20.66 C ATOM 396 CD2 PHE A 300 5.502 1.732 21.487 1.00 20.88 C ATOM 397 CE1 PHE A 300 4.110 -0.022 19.877 1.00 22.39 C ATOM 398 CE2 PHE A 300 4.680 2.218 20.504 1.00 20.31 C ATOM 399 CZ PHE A 300 3.982 1.350 19.694 1.00 21.57 C ATOM 400 N PHE A 301 6.971 -2.709 24.847 1.00 23.64 N ATOM 401 CA PHE A 301 8.026 -3.410 25.582 1.00 20.63 C ATOM 402 C PHE A 301 8.962 -4.114 24.611 1.00 24.08 C ATOM 403 O PHE A 301 8.520 -4.892 23.777 1.00 23.84 O ATOM 404 CB PHE A 301 7.460 -4.452 26.557 1.00 21.98 C ATOM 405 CG PHE A 301 6.583 -3.874 27.636 1.00 21.81 C ATOM 406 CD1 PHE A 301 5.316 -3.383 27.333 1.00 27.59 C ATOM 407 CD2 PHE A 301 7.016 -3.832 28.943 1.00 23.44 C ATOM 408 CE1 PHE A 301 4.505 -2.849 28.321 1.00 28.35 C ATOM 409 CE2 PHE A 301 6.201 -3.302 29.942 1.00 28.14 C ATOM 410 CZ PHE A 301 4.952 -2.814 29.622 1.00 24.05 C ATOM 411 N ILE A 302 10.256 -3.858 24.733 1.00 21.44 N ATOM 412 CA ILE A 302 11.225 -4.560 23.908 1.00 21.90 C ATOM 413 C ILE A 302 11.489 -5.946 24.497 1.00 26.93 C ATOM 414 O ILE A 302 11.998 -6.061 25.603 1.00 22.97 O ATOM 415 CB ILE A 302 12.515 -3.781 23.807 1.00 17.99 C ATOM 416 CG1 ILE A 302 12.275 -2.497 23.008 1.00 17.54 C ATOM 417 CG2 ILE A 302 13.592 -4.636 23.187 1.00 20.99 C ATOM 418 CD1 ILE A 302 13.465 -1.565 22.967 1.00 20.07 C ATOM 419 N THR A 303 11.118 -6.995 23.766 1.00 21.44 N ATOM 420 CA THR A 303 11.246 -8.349 24.277 1.00 21.22 C ATOM 421 C THR A 303 12.353 -9.162 23.611 1.00 26.21 C ATOM 422 O THR A 303 12.870 -10.095 24.209 1.00 27.63 O ATOM 423 CB THR A 303 9.942 -9.100 24.112 1.00 22.18 C ATOM 424 OG1 THR A 303 9.668 -9.248 22.718 1.00 27.00 O ATOM 425 CG2 THR A 303 8.803 -8.319 24.752 1.00 25.29 C ATOM 426 N HIS A 304 12.696 -8.829 22.370 1.00 24.71 N ATOM 427 CA HIS A 304 13.745 -9.555 21.639 1.00 27.93 C ATOM 428 C HIS A 304 14.756 -8.638 20.979 1.00 26.76 C ATOM 429 O HIS A 304 14.388 -7.616 20.398 1.00 23.42 O ATOM 430 CB HIS A 304 13.156 -10.439 20.541 1.00 26.46 C ATOM 431 CG HIS A 304 12.222 -11.491 21.036 1.00 31.18 C ATOM 432 ND1 HIS A 304 10.984 -11.197 21.561 1.00 31.85 N ATOM 433 CD2 HIS A 304 12.335 -12.839 21.066 1.00 36.57 C ATOM 434 CE1 HIS A 304 10.374 -12.318 21.900 1.00 33.59 C ATOM 435 NE2 HIS A 304 11.173 -13.327 21.611 1.00 42.34 N ATOM 436 N LEU A 305 16.023 -9.031 21.058 1.00 25.02 N ATOM 437 CA LEU A 305 17.099 -8.408 20.297 1.00 20.38 C ATOM 438 C LEU A 305 17.430 -9.347 19.142 1.00 20.92 C ATOM 439 O LEU A 305 17.976 -10.429 19.356 1.00 23.85 O ATOM 440 CB LEU A 305 18.320 -8.157 21.192 1.00 20.59 C ATOM 441 CG LEU A 305 19.657 -7.761 20.555 1.00 22.87 C ATOM 442 CD1 LEU A 305 19.604 -6.388 19.913 1.00 14.70 C ATOM 443 CD2 LEU A 305 20.769 -7.820 21.595 1.00 21.53 C ATOM 444 N VAL A 306 17.059 -8.963 17.923 1.00 18.55 N ATOM 445 CA VAL A 306 17.291 -9.831 16.769 1.00 17.94 C ATOM 446 C VAL A 306 18.532 -9.399 15.992 1.00 20.86 C ATOM 447 O VAL A 306 18.625 -8.252 15.558 1.00 15.99 O ATOM 448 CB VAL A 306 16.108 -9.832 15.827 1.00 21.85 C ATOM 449 CG1 VAL A 306 16.352 -10.826 14.683 1.00 20.24 C ATOM 450 CG2 VAL A 306 14.818 -10.151 16.597 1.00 22.01 C ATOM 451 N ILE A 307 19.489 -10.313 15.836 1.00 19.50 N ATOM 452 CA ILE A 307 20.672 -10.042 15.019 1.00 19.60 C ATOM 453 C ILE A 307 20.431 -10.635 13.632 1.00 23.26 C ATOM 454 O ILE A 307 20.511 -11.849 13.434 1.00 22.52 O ATOM 455 CB ILE A 307 21.967 -10.635 15.620 1.00 22.03 C ATOM 456 CG1 ILE A 307 22.001 -10.472 17.148 1.00 23.70 C ATOM 457 CG2 ILE A 307 23.215 -9.987 14.991 1.00 17.22 C ATOM 458 CD1 ILE A 307 22.158 -9.041 17.630 1.00 22.25 C ATOM 459 N PRO A 308 20.138 -9.769 12.661 1.00 20.57 N ATOM 460 CA PRO A 308 19.810 -10.216 11.300 1.00 21.49 C ATOM 461 C PRO A 308 21.045 -10.676 10.516 1.00 26.42 C ATOM 462 O PRO A 308 22.182 -10.382 10.926 1.00 21.55 O ATOM 463 CB PRO A 308 19.222 -8.965 10.676 1.00 21.66 C ATOM 464 CG PRO A 308 20.019 -7.851 11.338 1.00 20.06 C ATOM 465 CD PRO A 308 20.251 -8.297 12.753 1.00 17.71 C ATOM 466 N LEU A 309 20.822 -11.377 9.406 1.00 24.25 N ATOM 467 CA LEU A 309 21.900 -11.656 8.467 1.00 25.95 C ATOM 468 C LEU A 309 22.436 -10.321 8.006 1.00 24.67 C ATOM 469 O LEU A 309 21.667 -9.443 7.615 1.00 21.65 O ATOM 470 CB LEU A 309 21.414 -12.484 7.280 1.00 28.20 C ATOM 471 CG LEU A 309 21.499 -14.006 7.429 1.00 35.77 C ATOM 472 CD1 LEU A 309 20.850 -14.687 6.226 1.00 44.92 C ATOM 473 CD2 LEU A 309 22.954 -14.475 7.606 1.00 34.15 C ATOM 474 N GLN A 310 23.748 -10.149 8.085 1.00 23.89 N ATOM 475 CA GLN A 310 24.333 -8.865 7.747 1.00 27.64 C ATOM 476 C GLN A 310 25.757 -8.933 7.224 1.00 29.41 C ATOM 477 O GLN A 310 26.391 -9.989 7.197 1.00 29.56 O ATOM 478 CB GLN A 310 24.307 -7.956 8.966 1.00 25.52 C ATOM 479 CG GLN A 310 24.884 -8.587 10.199 1.00 21.39 C ATOM 480 CD GLN A 310 24.650 -7.726 11.409 1.00 23.44 C ATOM 481 OE1 GLN A 310 25.356 -6.736 11.629 1.00 24.42 O ATOM 482 NE2 GLN A 310 23.630 -8.080 12.196 1.00 22.06 N ATOM 483 N GLU A 311 26.241 -7.763 6.834 1.00 30.13 N ATOM 484 CA GLU A 311 27.600 -7.567 6.370 1.00 32.74 C ATOM 485 C GLU A 311 28.114 -6.293 7.021 1.00 38.84 C ATOM 486 O GLU A 311 27.320 -5.457 7.458 1.00 30.91 O ATOM 487 CB GLU A 311 27.651 -7.460 4.846 1.00 34.25 C ATOM 488 CG GLU A 311 26.933 -6.225 4.316 1.00 37.58 C ATOM 489 CD GLU A 311 26.855 -6.190 2.802 1.00 46.79 C ATOM 490 OE1 GLU A 311 27.454 -7.079 2.154 1.00 48.61 O ATOM 491 OE2 GLU A 311 26.199 -5.265 2.267 1.00 44.01 O ATOM 492 N ALA A 312 29.433 -6.143 7.096 1.00 34.74 N ATOM 493 CA ALA A 312 30.000 -5.029 7.830 1.00 36.27 C ATOM 494 C ALA A 312 31.435 -4.712 7.429 1.00 39.91 C ATOM 495 O ALA A 312 32.133 -5.538 6.851 1.00 44.07 O ATOM 496 CB ALA A 312 29.938 -5.311 9.317 1.00 39.55 C ATOM 497 N THR A 313 31.845 -3.487 7.739 1.00 38.48 N ATOM 498 CA THR A 313 33.238 -3.073 7.718 1.00 38.27 C ATOM 499 C THR A 313 33.504 -2.411 9.054 1.00 41.03 C ATOM 500 O THR A 313 32.709 -2.534 9.988 1.00 41.11 O ATOM 501 CB THR A 313 33.546 -2.093 6.575 1.00 35.07 C ATOM 502 OG1 THR A 313 33.149 -0.769 6.955 1.00 36.25 O ATOM 503 CG2 THR A 313 32.819 -2.509 5.302 1.00 33.76 C ATOM 504 N SER A 314 34.619 -1.702 9.163 1.00 40.04 N ATOM 505 CA SER A 314 34.873 -0.931 10.373 1.00 45.27 C ATOM 506 C SER A 314 34.094 0.378 10.362 1.00 38.56 C ATOM 507 O SER A 314 34.055 1.087 11.367 1.00 39.92 O ATOM 508 CB SER A 314 36.367 -0.673 10.544 1.00 46.36 C ATOM 509 OG SER A 314 36.899 -0.057 9.385 1.00 51.79 O ATOM 510 N ASP A 315 33.437 0.650 9.237 1.00 38.89 N ATOM 511 CA ASP A 315 32.719 1.896 9.012 1.00 42.27 C ATOM 512 C ASP A 315 31.220 1.698 8.813 1.00 39.44 C ATOM 513 O ASP A 315 30.457 2.650 8.901 1.00 37.73 O ATOM 514 CB ASP A 315 33.253 2.622 7.768 1.00 46.25 C ATOM 515 CG ASP A 315 34.548 3.353 8.020 1.00 56.42 C ATOM 516 OD1 ASP A 315 35.428 2.800 8.718 1.00 53.93 O ATOM 517 OD2 ASP A 315 34.673 4.495 7.524 1.00 64.24 O ATOM 518 N THR A 316 30.815 0.479 8.476 1.00 36.91 N ATOM 519 CA THR A 316 29.445 0.224 8.059 1.00 33.09 C ATOM 520 C THR A 316 28.901 -1.112 8.542 1.00 35.60 C ATOM 521 O THR A 316 29.643 -2.002 8.952 1.00 32.33 O ATOM 522 CB THR A 316 29.308 0.237 6.529 1.00 34.92 C ATOM 523 OG1 THR A 316 30.162 -0.767 5.976 1.00 40.17 O ATOM 524 CG2 THR A 316 29.684 1.582 5.947 1.00 37.74 C ATOM 525 N CYS A 317 27.583 -1.240 8.480 1.00 31.72 N ATOM 526 CA CYS A 317 26.921 -2.527 8.636 1.00 26.88 C ATOM 527 C CYS A 317 25.564 -2.431 7.954 1.00 27.10 C ATOM 528 O CYS A 317 25.013 -1.345 7.810 1.00 21.92 O ATOM 529 CB CYS A 317 26.795 -2.926 10.116 1.00 30.25 C ATOM 530 SG CYS A 317 25.980 -1.745 11.236 1.00 29.25 S ATOM 531 N GLY A 318 25.050 -3.560 7.499 1.00 26.41 N ATOM 532 CA GLY A 318 23.798 -3.567 6.777 1.00 28.66 C ATOM 533 C GLY A 318 23.213 -4.957 6.692 1.00 33.00 C ATOM 534 O GLY A 318 23.964 -5.929 6.632 1.00 31.30 O ATOM 535 N THR A 319 21.881 -5.047 6.703 1.00 22.66 N ATOM 536 CA THR A 319 21.169 -6.311 6.528 1.00 27.09 C ATOM 537 C THR A 319 21.350 -6.839 5.095 1.00 29.55 C ATOM 538 O THR A 319 21.468 -6.050 4.152 1.00 22.10 O ATOM 539 CB THR A 319 19.626 -6.168 6.827 1.00 23.64 C ATOM 540 OG1 THR A 319 19.123 -4.960 6.236 1.00 22.54 O ATOM 541 CG2 THR A 319 19.340 -6.148 8.329 1.00 22.78 C ATOM 542 N THR A 320 21.341 -8.165 4.936 1.00 24.84 N ATOM 543 CA THR A 320 21.416 -8.775 3.608 1.00 25.84 C ATOM 544 C THR A 320 20.288 -9.756 3.319 1.00 32.28 C ATOM 545 O THR A 320 20.247 -10.352 2.237 1.00 33.72 O ATOM 546 CB THR A 320 22.752 -9.512 3.411 1.00 29.56 C ATOM 547 OG1 THR A 320 22.910 -10.483 4.446 1.00 28.71 O ATOM 548 CG2 THR A 320 23.910 -8.534 3.460 1.00 24.53 C ATOM 549 N ASP A 321 19.383 -9.954 4.279 1.00 27.15 N ATOM 550 CA ASP A 321 18.213 -10.801 4.029 1.00 30.77 C ATOM 551 C ASP A 321 17.016 -10.392 4.883 1.00 29.17 C ATOM 552 O ASP A 321 16.687 -11.027 5.883 1.00 35.90 O ATOM 553 CB ASP A 321 18.548 -12.269 4.272 1.00 33.79 C ATOM 554 CG ASP A 321 17.377 -13.189 3.977 1.00 37.30 C ATOM 555 OD1 ASP A 321 16.518 -12.825 3.147 1.00 39.67 O ATOM 556 OD2 ASP A 321 17.330 -14.288 4.560 1.00 41.58 O ATOM 557 N GLU A 322 16.337 -9.344 4.471 1.00 22.91 N ATOM 558 CA GLU A 322 15.242 -8.836 5.269 1.00 23.46 C ATOM 559 C GLU A 322 13.991 -9.729 5.168 1.00 30.14 C ATOM 560 O GLU A 322 13.055 -9.604 5.968 1.00 25.33 O ATOM 561 CB GLU A 322 14.940 -7.395 4.855 1.00 22.49 C ATOM 562 CG GLU A 322 16.138 -6.443 5.001 1.00 19.34 C ATOM 563 CD GLU A 322 17.093 -6.459 3.803 1.00 23.75 C ATOM 564 OE1 GLU A 322 16.759 -7.088 2.776 1.00 19.99 O ATOM 565 OE2 GLU A 322 18.183 -5.838 3.892 1.00 22.92 O ATOM 566 N ALA A 323 13.985 -10.646 4.203 1.00 30.79 N ATOM 567 CA ALA A 323 12.843 -11.548 4.015 1.00 33.25 C ATOM 568 C ALA A 323 12.657 -12.471 5.217 1.00 32.24 C ATOM 569 O ALA A 323 11.538 -12.650 5.727 1.00 28.06 O ATOM 570 CB ALA A 323 13.015 -12.374 2.743 1.00 29.37 C ATOM 571 N SER A 324 13.754 -13.069 5.664 1.00 29.94 N ATOM 572 CA SER A 324 13.699 -13.969 6.803 1.00 31.69 C ATOM 573 C SER A 324 13.586 -13.189 8.127 1.00 28.14 C ATOM 574 O SER A 324 13.093 -13.717 9.126 1.00 27.12 O ATOM 575 CB SER A 324 14.919 -14.898 6.798 1.00 35.45 C ATOM 576 OG SER A 324 16.120 -14.172 6.956 1.00 44.05 O ATOM 577 N LEU A 325 14.026 -11.935 8.139 1.00 26.69 N ATOM 578 CA LEU A 325 13.737 -11.073 9.286 1.00 27.38 C ATOM 579 C LEU A 325 12.231 -10.882 9.388 1.00 22.96 C ATOM 580 O LEU A 325 11.647 -11.050 10.454 1.00 25.14 O ATOM 581 CB LEU A 325 14.438 -9.719 9.161 1.00 24.37 C ATOM 582 CG LEU A 325 14.295 -8.633 10.233 1.00 25.89 C ATOM 583 CD1 LEU A 325 14.742 -9.114 11.606 1.00 24.27 C ATOM 584 CD2 LEU A 325 15.139 -7.435 9.820 1.00 22.21 C ATOM 585 N PHE A 326 11.605 -10.535 8.268 1.00 20.91 N ATOM 586 CA PHE A 326 10.153 -10.405 8.211 1.00 18.21 C ATOM 587 C PHE A 326 9.451 -11.669 8.694 1.00 23.75 C ATOM 588 O PHE A 326 8.644 -11.609 9.602 1.00 27.78 O ATOM 589 CB PHE A 326 9.665 -10.069 6.799 1.00 20.40 C ATOM 590 CG PHE A 326 8.176 -10.214 6.650 1.00 23.03 C ATOM 591 CD1 PHE A 326 7.320 -9.250 7.164 1.00 24.54 C ATOM 592 CD2 PHE A 326 7.629 -11.334 6.034 1.00 26.49 C ATOM 593 CE1 PHE A 326 5.945 -9.394 7.055 1.00 25.87 C ATOM 594 CE2 PHE A 326 6.255 -11.487 5.930 1.00 25.42 C ATOM 595 CZ PHE A 326 5.413 -10.513 6.433 1.00 27.51 C ATOM 596 N GLU A 327 9.757 -12.809 8.082 1.00 26.50 N ATOM 597 CA GLU A 327 9.155 -14.087 8.474 1.00 26.19 C ATOM 598 C GLU A 327 9.242 -14.353 9.960 1.00 27.86 C ATOM 599 O GLU A 327 8.282 -14.834 10.558 1.00 28.15 O ATOM 600 CB GLU A 327 9.825 -15.255 7.752 1.00 31.37 C ATOM 601 CG GLU A 327 9.244 -15.598 6.414 1.00 36.00 C ATOM 602 CD GLU A 327 10.093 -16.628 5.693 1.00 51.65 C ATOM 603 OE1 GLU A 327 10.829 -17.376 6.381 1.00 46.87 O ATOM 604 OE2 GLU A 327 10.044 -16.674 4.441 1.00 57.32 O ATOM 605 N PHE A 328 10.409 -14.094 10.546 1.00 27.16 N ATOM 606 CA PHE A 328 10.569 -14.297 11.975 1.00 26.90 C ATOM 607 C PHE A 328 9.613 -13.404 12.754 1.00 27.27 C ATOM 608 O PHE A 328 8.846 -13.882 13.597 1.00 24.08 O ATOM 609 CB PHE A 328 12.006 -14.031 12.437 1.00 25.67 C ATOM 610 CG PHE A 328 12.169 -14.187 13.918 1.00 30.38 C ATOM 611 CD1 PHE A 328 12.357 -15.444 14.472 1.00 32.76 C ATOM 612 CD2 PHE A 328 12.066 -13.097 14.763 1.00 29.48 C ATOM 613 CE1 PHE A 328 12.479 -15.605 15.830 1.00 33.77 C ATOM 614 CE2 PHE A 328 12.187 -13.248 16.131 1.00 33.62 C ATOM 615 CZ PHE A 328 12.391 -14.508 16.664 1.00 33.85 C ATOM 616 N GLN A 329 9.656 -12.103 12.465 1.00 25.54 N ATOM 617 CA GLN A 329 8.782 -11.145 13.132 1.00 22.70 C ATOM 618 C GLN A 329 7.316 -11.450 12.893 1.00 26.37 C ATOM 619 O GLN A 329 6.523 -11.399 13.822 1.00 24.41 O ATOM 620 CB GLN A 329 9.102 -9.723 12.685 1.00 19.35 C ATOM 621 CG GLN A 329 10.457 -9.267 13.199 1.00 21.23 C ATOM 622 CD GLN A 329 10.702 -7.801 12.936 1.00 18.97 C ATOM 623 OE1 GLN A 329 11.597 -7.439 12.181 1.00 18.86 O ATOM 624 NE2 GLN A 329 9.909 -6.950 13.561 1.00 15.32 N ATOM 625 N ASP A 330 6.960 -11.767 11.654 1.00 24.41 N ATOM 626 CA ASP A 330 5.584 -12.113 11.314 1.00 28.06 C ATOM 627 C ASP A 330 5.142 -13.363 12.085 1.00 30.18 C ATOM 628 O ASP A 330 4.049 -13.399 12.654 1.00 33.74 O ATOM 629 CB ASP A 330 5.449 -12.327 9.805 1.00 28.67 C ATOM 630 CG ASP A 330 4.008 -12.548 9.363 1.00 34.43 C ATOM 631 OD1 ASP A 330 3.140 -11.689 9.645 1.00 35.87 O ATOM 632 OD2 ASP A 330 3.740 -13.600 8.741 1.00 40.87 O ATOM 633 N LYS A 331 6.006 -14.375 12.128 1.00 31.08 N ATOM 634 CA LYS A 331 5.674 -15.621 12.826 1.00 32.00 C ATOM 635 C LYS A 331 5.414 -15.389 14.313 1.00 33.48 C ATOM 636 O LYS A 331 4.473 -15.935 14.876 1.00 34.58 O ATOM 637 CB LYS A 331 6.779 -16.673 12.668 1.00 28.79 C ATOM 638 CG LYS A 331 6.526 -17.934 13.528 1.00 37.02 C ATOM 639 CD LYS A 331 7.489 -19.083 13.247 1.00 35.32 C ATOM 640 CE LYS A 331 7.067 -20.333 14.027 1.00 37.63 C ATOM 641 NZ LYS A 331 7.708 -21.601 13.565 1.00 38.37 N ATOM 642 N HIS A 332 6.247 -14.586 14.956 1.00 28.01 N ATOM 643 CA HIS A 332 6.119 -14.419 16.392 1.00 30.54 C ATOM 644 C HIS A 332 5.423 -13.121 16.799 1.00 27.60 C ATOM 645 O HIS A 332 5.490 -12.724 17.960 1.00 31.69 O ATOM 646 CB HIS A 332 7.499 -14.507 17.045 1.00 28.24 C ATOM 647 CG HIS A 332 8.188 -15.821 16.815 1.00 35.15 C ATOM 648 ND1 HIS A 332 9.119 -16.012 15.815 1.00 35.78 N ATOM 649 CD2 HIS A 332 8.072 -17.010 17.449 1.00 35.60 C ATOM 650 CE1 HIS A 332 9.549 -17.260 15.845 1.00 31.64 C ATOM 651 NE2 HIS A 332 8.931 -17.886 16.830 1.00 37.18 N ATOM 652 N ASN A 333 4.748 -12.477 15.849 1.00 30.36 N ATOM 653 CA ASN A 333 4.029 -11.225 16.110 1.00 33.86 C ATOM 654 C ASN A 333 4.874 -10.188 16.869 1.00 31.84 C ATOM 655 O ASN A 333 4.558 -9.784 17.997 1.00 28.87 O ATOM 656 CB ASN A 333 2.739 -11.518 16.874 1.00 34.44 C ATOM 657 CG ASN A 333 1.817 -12.451 16.108 1.00 39.92 C ATOM 658 OD1 ASN A 333 1.223 -12.067 15.101 1.00 39.81 O ATOM 659 ND2 ASN A 333 1.708 -13.691 16.576 1.00 41.72 N ATOM 660 N LEU A 334 5.957 -9.764 16.238 1.00 25.62 N ATOM 661 CA LEU A 334 6.904 -8.867 16.875 1.00 26.15 C ATOM 662 C LEU A 334 6.992 -7.556 16.116 1.00 25.83 C ATOM 663 O LEU A 334 7.243 -7.533 14.895 1.00 20.94 O ATOM 664 CB LEU A 334 8.284 -9.521 16.951 1.00 22.67 C ATOM 665 CG LEU A 334 8.517 -10.585 18.012 1.00 29.72 C ATOM 666 CD1 LEU A 334 9.879 -11.229 17.784 1.00 26.69 C ATOM 667 CD2 LEU A 334 8.421 -9.962 19.395 1.00 24.28 C ATOM 668 N LEU A 335 6.790 -6.463 16.839 1.00 22.89 N ATOM 669 CA LEU A 335 6.914 -5.145 16.249 1.00 18.25 C ATOM 670 C LEU A 335 8.372 -4.750 16.159 1.00 19.15 C ATOM 671 O LEU A 335 9.172 -5.115 17.012 1.00 19.08 O ATOM 672 CB LEU A 335 6.154 -4.119 17.066 1.00 21.10 C ATOM 673 CG LEU A 335 4.651 -4.306 17.117 1.00 21.87 C ATOM 674 CD1 LEU A 335 4.056 -3.447 18.231 1.00 22.38 C ATOM 675 CD2 LEU A 335 4.071 -3.956 15.771 1.00 20.98 C ATOM 676 N THR A 336 8.700 -3.995 15.119 1.00 19.60 N ATOM 677 CA THR A 336 9.985 -3.338 15.023 1.00 17.67 C ATOM 678 C THR A 336 9.899 -2.057 15.844 1.00 15.22 C ATOM 679 O THR A 336 9.115 -1.166 15.505 1.00 17.11 O ATOM 680 CB THR A 336 10.347 -3.019 13.558 1.00 15.94 C ATOM 681 OG1 THR A 336 10.375 -4.239 12.807 1.00 15.42 O ATOM 682 CG2 THR A 336 11.690 -2.330 13.482 1.00 17.09 C ATOM 683 N LEU A 337 10.678 -1.967 16.923 1.00 13.69 N ATOM 684 CA LEU A 337 10.608 -0.796 17.805 1.00 14.42 C ATOM 685 C LEU A 337 11.820 0.112 17.694 1.00 14.13 C ATOM 686 O LEU A 337 11.852 1.236 18.230 1.00 14.96 O ATOM 687 CB LEU A 337 10.448 -1.242 19.256 1.00 16.22 C ATOM 688 CG LEU A 337 9.131 -1.989 19.519 1.00 19.26 C ATOM 689 CD1 LEU A 337 9.018 -2.379 20.998 1.00 19.73 C ATOM 690 CD2 LEU A 337 7.920 -1.188 19.054 1.00 18.59 C ATOM 691 N GLY A 338 12.839 -0.376 17.011 1.00 15.31 N ATOM 692 CA GLY A 338 14.041 0.402 16.861 1.00 13.54 C ATOM 693 C GLY A 338 15.163 -0.512 16.490 1.00 14.00 C ATOM 694 O GLY A 338 14.959 -1.683 16.127 1.00 15.79 O ATOM 695 N TRP A 339 16.370 0.007 16.601 1.00 12.59 N ATOM 696 CA TRP A 339 17.498 -0.793 16.213 1.00 15.74 C ATOM 697 C TRP A 339 18.750 -0.348 16.969 1.00 17.00 C ATOM 698 O TRP A 339 18.730 0.639 17.711 1.00 16.70 O ATOM 699 CB TRP A 339 17.681 -0.726 14.699 1.00 16.90 C ATOM 700 CG TRP A 339 17.981 0.668 14.163 1.00 17.51 C ATOM 701 CD1 TRP A 339 17.161 1.766 14.188 1.00 18.48 C ATOM 702 CD2 TRP A 339 19.175 1.080 13.507 1.00 17.56 C ATOM 703 NE1 TRP A 339 17.784 2.847 13.589 1.00 17.31 N ATOM 704 CE2 TRP A 339 19.033 2.449 13.168 1.00 17.90 C ATOM 705 CE3 TRP A 339 20.360 0.419 13.161 1.00 15.97 C ATOM 706 CZ2 TRP A 339 20.026 3.173 12.505 1.00 17.56 C ATOM 707 CZ3 TRP A 339 21.361 1.147 12.497 1.00 19.85 C ATOM 708 CH2 TRP A 339 21.181 2.503 12.179 1.00 18.53 C ATOM 709 N ILE A 340 19.825 -1.108 16.809 1.00 18.44 N ATOM 710 CA ILE A 340 21.050 -0.850 17.557 1.00 17.08 C ATOM 711 C ILE A 340 22.249 -1.234 16.690 1.00 20.32 C ATOM 712 O ILE A 340 22.173 -2.203 15.931 1.00 19.63 O ATOM 713 CB ILE A 340 21.046 -1.628 18.911 1.00 19.71 C ATOM 714 CG1 ILE A 340 22.328 -1.372 19.722 1.00 18.88 C ATOM 715 CG2 ILE A 340 20.818 -3.127 18.681 1.00 14.40 C ATOM 716 CD1 ILE A 340 22.222 -1.829 21.166 1.00 20.00 C ATOM 717 N HIS A 341 23.334 -0.453 16.774 1.00 22.23 N ATOM 718 CA HIS A 341 24.599 -0.847 16.155 1.00 21.55 C ATOM 719 C HIS A 341 25.829 -0.309 16.907 1.00 24.41 C ATOM 720 O HIS A 341 25.717 0.580 17.749 1.00 26.66 O ATOM 721 CB HIS A 341 24.623 -0.426 14.670 1.00 22.87 C ATOM 722 CG HIS A 341 24.741 1.049 14.432 1.00 25.04 C ATOM 723 ND1 HIS A 341 23.790 1.959 14.849 1.00 23.10 N ATOM 724 CD2 HIS A 341 25.679 1.772 13.771 1.00 25.26 C ATOM 725 CE1 HIS A 341 24.144 3.173 14.465 1.00 22.30 C ATOM 726 NE2 HIS A 341 25.287 3.088 13.815 1.00 27.91 N ATOM 727 N THR A 342 26.999 -0.885 16.636 1.00 27.98 N ATOM 728 CA THR A 342 28.219 -0.486 17.350 1.00 31.82 C ATOM 729 C THR A 342 29.094 0.475 16.563 1.00 35.19 C ATOM 730 O THR A 342 29.122 0.448 15.332 1.00 30.03 O ATOM 731 CB THR A 342 29.134 -1.689 17.712 1.00 32.15 C ATOM 732 OG1 THR A 342 29.490 -2.392 16.519 1.00 28.75 O ATOM 733 CG2 THR A 342 28.466 -2.628 18.708 1.00 32.63 C ATOM 734 N HIS A 343 29.813 1.312 17.306 1.00 35.50 N ATOM 735 CA HIS A 343 30.949 2.050 16.779 1.00 39.39 C ATOM 736 C HIS A 343 32.202 1.526 17.459 1.00 39.07 C ATOM 737 O HIS A 343 32.551 1.992 18.544 1.00 41.59 O ATOM 738 CB HIS A 343 30.799 3.544 17.021 1.00 36.12 C ATOM 739 CG HIS A 343 29.943 4.233 16.012 1.00 35.05 C ATOM 740 ND1 HIS A 343 29.490 5.522 16.180 1.00 34.14 N ATOM 741 CD2 HIS A 343 29.453 3.807 14.822 1.00 34.96 C ATOM 742 CE1 HIS A 343 28.752 5.862 15.137 1.00 34.85 C ATOM 743 NE2 HIS A 343 28.712 4.842 14.300 1.00 32.09 N ATOM 744 N PRO A 344 32.867 0.540 16.838 1.00 39.16 N ATOM 745 CA PRO A 344 33.991 -0.127 17.503 1.00 45.14 C ATOM 746 C PRO A 344 35.084 0.863 17.914 1.00 46.01 C ATOM 747 O PRO A 344 35.568 0.790 19.041 1.00 40.96 O ATOM 748 CB PRO A 344 34.487 -1.112 16.441 1.00 42.02 C ATOM 749 CG PRO A 344 33.269 -1.403 15.629 1.00 42.73 C ATOM 750 CD PRO A 344 32.561 -0.079 15.540 1.00 36.03 C ATOM 751 N THR A 345 35.417 1.804 17.036 1.00 41.85 N ATOM 752 CA THR A 345 36.487 2.752 17.323 1.00 43.54 C ATOM 753 C THR A 345 35.997 4.183 17.530 1.00 45.83 C ATOM 754 O THR A 345 36.722 5.020 18.070 1.00 47.53 O ATOM 755 CB THR A 345 37.535 2.758 16.190 1.00 43.30 C ATOM 756 OG1 THR A 345 36.957 3.286 14.988 1.00 44.46 O ATOM 757 CG2 THR A 345 38.037 1.348 15.923 1.00 48.67 C ATOM 758 N GLN A 346 34.769 4.467 17.116 1.00 38.99 N ATOM 759 CA GLN A 346 34.348 5.850 16.983 1.00 32.67 C ATOM 760 C GLN A 346 33.700 6.390 18.242 1.00 35.13 C ATOM 761 O GLN A 346 33.486 5.664 19.217 1.00 36.70 O ATOM 762 CB GLN A 346 33.385 6.001 15.801 1.00 36.41 C ATOM 763 CG GLN A 346 33.932 5.520 14.456 1.00 38.77 C ATOM 764 CD GLN A 346 33.584 4.062 14.149 1.00 39.29 C ATOM 765 OE1 GLN A 346 33.561 3.215 15.043 1.00 37.67 O ATOM 766 NE2 GLN A 346 33.305 3.770 12.875 1.00 35.79 N ATOM 767 N THR A 347 33.403 7.683 18.224 1.00 30.56 N ATOM 768 CA THR A 347 32.607 8.272 19.284 1.00 34.41 C ATOM 769 C THR A 347 31.145 7.880 19.101 1.00 33.05 C ATOM 770 O THR A 347 30.764 7.275 18.093 1.00 29.33 O ATOM 771 CB THR A 347 32.719 9.807 19.312 1.00 37.94 C ATOM 772 OG1 THR A 347 32.770 10.306 17.970 1.00 40.39 O ATOM 773 CG2 THR A 347 33.972 10.240 20.059 1.00 38.33 C ATOM 774 N CYS A 348 30.340 8.234 20.090 1.00 31.16 N ATOM 775 CA CYS A 348 28.929 7.932 20.070 1.00 34.36 C ATOM 776 C CYS A 348 28.152 9.056 19.400 1.00 34.40 C ATOM 777 O CYS A 348 28.001 10.143 19.965 1.00 32.71 O ATOM 778 CB CYS A 348 28.424 7.713 21.482 1.00 38.70 C ATOM 779 SG CYS A 348 26.690 7.268 21.545 1.00 37.13 S ATOM 780 N PHE A 349 27.671 8.779 18.192 1.00 33.96 N ATOM 781 CA PHE A 349 26.922 9.752 17.394 1.00 33.41 C ATOM 782 C PHE A 349 26.165 9.007 16.296 1.00 28.77 C ATOM 783 O PHE A 349 26.515 7.871 15.964 1.00 26.05 O ATOM 784 CB PHE A 349 27.858 10.792 16.764 1.00 26.72 C ATOM 785 CG PHE A 349 28.735 10.215 15.699 1.00 27.94 C ATOM 786 CD1 PHE A 349 29.869 9.502 16.038 1.00 29.02 C ATOM 787 CD2 PHE A 349 28.409 10.348 14.357 1.00 30.40 C ATOM 788 CE1 PHE A 349 30.674 8.950 15.061 1.00 31.66 C ATOM 789 CE2 PHE A 349 29.207 9.792 13.373 1.00 26.57 C ATOM 790 CZ PHE A 349 30.338 9.092 13.723 1.00 29.52 C ATOM 791 N MET A 350 25.131 9.653 15.747 1.00 24.83 N ATOM 792 CA MET A 350 24.419 9.139 14.582 1.00 22.42 C ATOM 793 C MET A 350 25.091 9.585 13.293 1.00 23.47 C ATOM 794 O MET A 350 25.094 10.778 12.977 1.00 22.88 O ATOM 795 CB MET A 350 22.966 9.609 14.573 1.00 14.03 C ATOM 796 CG MET A 350 22.089 9.042 15.687 1.00 20.13 C ATOM 797 SD MET A 350 21.688 7.319 15.427 1.00 20.45 S ATOM 798 CE MET A 350 20.613 7.461 13.971 1.00 13.60 C ATOM 799 N SER A 351 25.618 8.638 12.525 1.00 24.80 N ATOM 800 CA SER A 351 26.201 8.967 11.222 1.00 23.53 C ATOM 801 C SER A 351 25.130 9.301 10.169 1.00 27.25 C ATOM 802 O SER A 351 23.935 9.151 10.410 1.00 22.63 O ATOM 803 CB SER A 351 27.078 7.818 10.716 1.00 25.45 C ATOM 804 OG SER A 351 26.309 6.743 10.204 1.00 30.79 O ATOM 805 N SER A 352 25.576 9.756 9.003 1.00 23.85 N ATOM 806 CA SER A 352 24.686 10.018 7.880 1.00 28.42 C ATOM 807 C SER A 352 23.889 8.779 7.480 1.00 24.38 C ATOM 808 O SER A 352 22.691 8.870 7.248 1.00 25.37 O ATOM 809 CB SER A 352 25.473 10.521 6.669 1.00 30.36 C ATOM 810 OG SER A 352 24.586 10.882 5.626 1.00 33.26 O ATOM 811 N VAL A 353 24.566 7.637 7.385 1.00 24.73 N ATOM 812 CA VAL A 353 23.924 6.357 7.087 1.00 26.50 C ATOM 813 C VAL A 353 22.830 6.020 8.090 1.00 23.38 C ATOM 814 O VAL A 353 21.705 5.662 7.712 1.00 21.99 O ATOM 815 CB VAL A 353 24.915 5.187 7.111 1.00 28.06 C ATOM 816 CG1 VAL A 353 24.377 4.040 6.271 1.00 33.97 C ATOM 817 CG2 VAL A 353 26.265 5.617 6.603 1.00 42.02 C ATOM 818 N ALA A 354 23.194 6.108 9.365 1.00 22.57 N ATOM 819 CA ALA A 354 22.282 5.804 10.452 1.00 24.62 C ATOM 820 C ALA A 354 21.062 6.725 10.382 1.00 20.28 C ATOM 821 O ALA A 354 19.932 6.290 10.555 1.00 18.71 O ATOM 822 CB ALA A 354 22.995 5.929 11.808 1.00 16.94 C ATOM 823 N LEU A 355 21.286 7.993 10.088 1.00 17.52 N ATOM 824 CA LEU A 355 20.181 8.929 10.063 1.00 20.73 C ATOM 825 C LEU A 355 19.231 8.584 8.921 1.00 20.55 C ATOM 826 O LEU A 355 18.012 8.643 9.081 1.00 16.90 O ATOM 827 CB LEU A 355 20.682 10.374 9.949 1.00 19.41 C ATOM 828 CG LEU A 355 21.294 10.974 11.211 1.00 20.90 C ATOM 829 CD1 LEU A 355 21.998 12.281 10.872 1.00 20.71 C ATOM 830 CD2 LEU A 355 20.218 11.188 12.299 1.00 14.80 C ATOM 831 N HIS A 356 19.781 8.170 7.787 1.00 22.00 N ATOM 832 CA HIS A 356 18.927 7.779 6.675 1.00 22.86 C ATOM 833 C HIS A 356 18.148 6.490 6.977 1.00 22.31 C ATOM 834 O HIS A 356 16.963 6.376 6.643 1.00 21.40 O ATOM 835 CB HIS A 356 19.760 7.645 5.396 1.00 20.74 C ATOM 836 CG HIS A 356 19.814 8.915 4.613 1.00 23.07 C ATOM 837 ND1 HIS A 356 18.826 9.275 3.723 1.00 27.04 N ATOM 838 CD2 HIS A 356 20.681 9.955 4.655 1.00 27.90 C ATOM 839 CE1 HIS A 356 19.107 10.461 3.211 1.00 31.20 C ATOM 840 NE2 HIS A 356 20.229 10.895 3.759 1.00 31.25 N ATOM 841 N THR A 357 18.809 5.532 7.619 1.00 20.82 N ATOM 842 CA THR A 357 18.127 4.319 8.035 1.00 21.37 C ATOM 843 C THR A 357 17.020 4.659 9.014 1.00 18.48 C ATOM 844 O THR A 357 15.858 4.311 8.780 1.00 19.34 O ATOM 845 CB THR A 357 19.080 3.314 8.678 1.00 18.48 C ATOM 846 OG1 THR A 357 20.029 2.892 7.698 1.00 17.90 O ATOM 847 CG2 THR A 357 18.294 2.111 9.149 1.00 18.01 C ATOM 848 N HIS A 358 17.365 5.383 10.076 1.00 16.62 N ATOM 849 CA HIS A 358 16.407 5.637 11.157 1.00 13.83 C ATOM 850 C HIS A 358 15.208 6.473 10.760 1.00 17.37 C ATOM 851 O HIS A 358 14.102 6.294 11.314 1.00 12.74 O ATOM 852 CB HIS A 358 17.062 6.305 12.359 1.00 13.44 C ATOM 853 CG HIS A 358 16.174 6.290 13.563 1.00 12.62 C ATOM 854 ND1 HIS A 358 15.845 5.123 14.218 1.00 14.00 N ATOM 855 CD2 HIS A 358 15.471 7.278 14.170 1.00 12.16 C ATOM 856 CE1 HIS A 358 15.009 5.403 15.214 1.00 13.89 C ATOM 857 NE2 HIS A 358 14.760 6.691 15.191 1.00 14.82 N ATOM 858 N CYS A 359 15.410 7.393 9.818 1.00 15.58 N ATOM 859 CA CYS A 359 14.318 8.241 9.348 1.00 12.81 C ATOM 860 C CYS A 359 13.104 7.405 8.935 1.00 16.37 C ATOM 861 O CYS A 359 11.972 7.704 9.317 1.00 15.59 O ATOM 862 CB CYS A 359 14.769 9.103 8.175 1.00 18.57 C ATOM 863 SG CYS A 359 13.544 10.285 7.644 1.00 17.82 S ATOM 864 N SER A 360 13.357 6.361 8.160 1.00 14.17 N ATOM 865 CA SER A 360 12.311 5.471 7.683 1.00 19.19 C ATOM 866 C SER A 360 11.619 4.725 8.819 1.00 18.91 C ATOM 867 O SER A 360 10.391 4.582 8.795 1.00 14.12 O ATOM 868 CB SER A 360 12.893 4.481 6.676 1.00 17.61 C ATOM 869 OG SER A 360 13.346 5.185 5.527 1.00 21.33 O ATOM 870 N TYR A 361 12.398 4.250 9.799 1.00 17.38 N ATOM 871 CA TYR A 361 11.827 3.580 10.976 1.00 15.37 C ATOM 872 C TYR A 361 10.970 4.497 11.801 1.00 14.54 C ATOM 873 O TYR A 361 9.929 4.080 12.303 1.00 17.39 O ATOM 874 CB TYR A 361 12.913 2.985 11.867 1.00 14.78 C ATOM 875 CG TYR A 361 13.503 1.765 11.244 1.00 19.00 C ATOM 876 CD1 TYR A 361 14.565 1.874 10.350 1.00 19.57 C ATOM 877 CD2 TYR A 361 12.986 0.512 11.507 1.00 17.22 C ATOM 878 CE1 TYR A 361 15.102 0.771 9.760 1.00 23.08 C ATOM 879 CE2 TYR A 361 13.529 -0.614 10.911 1.00 24.65 C ATOM 880 CZ TYR A 361 14.588 -0.472 10.039 1.00 22.47 C ATOM 881 OH TYR A 361 15.145 -1.568 9.426 1.00 21.41 O ATOM 882 N GLN A 362 11.394 5.742 11.949 1.00 11.45 N ATOM 883 CA GLN A 362 10.664 6.676 12.781 1.00 15.92 C ATOM 884 C GLN A 362 9.401 7.209 12.083 1.00 16.85 C ATOM 885 O GLN A 362 8.430 7.559 12.746 1.00 15.87 O ATOM 886 CB GLN A 362 11.568 7.828 13.195 1.00 14.87 C ATOM 887 CG GLN A 362 11.022 8.706 14.304 1.00 13.48 C ATOM 888 CD GLN A 362 12.064 9.673 14.819 1.00 18.19 C ATOM 889 OE1 GLN A 362 13.274 9.407 14.736 1.00 15.12 O ATOM 890 NE2 GLN A 362 11.609 10.796 15.365 1.00 12.30 N ATOM 891 N LEU A 363 9.423 7.287 10.754 1.00 16.87 N ATOM 892 CA LEU A 363 8.206 7.584 9.994 1.00 17.02 C ATOM 893 C LEU A 363 7.169 6.476 10.171 1.00 16.53 C ATOM 894 O LEU A 363 5.985 6.749 10.259 1.00 24.02 O ATOM 895 CB LEU A 363 8.527 7.771 8.514 1.00 17.66 C ATOM 896 CG LEU A 363 9.332 9.024 8.170 1.00 17.48 C ATOM 897 CD1 LEU A 363 9.889 8.930 6.771 1.00 21.95 C ATOM 898 CD2 LEU A 363 8.480 10.258 8.342 1.00 15.15 C ATOM 899 N MET A 364 7.624 5.230 10.216 1.00 14.22 N ATOM 900 CA MET A 364 6.726 4.090 10.367 1.00 15.16 C ATOM 901 C MET A 364 6.271 3.899 11.804 1.00 21.72 C ATOM 902 O MET A 364 5.229 3.305 12.048 1.00 17.60 O ATOM 903 CB MET A 364 7.397 2.822 9.857 1.00 16.52 C ATOM 904 CG MET A 364 7.640 2.852 8.354 1.00 19.12 C ATOM 905 SD MET A 364 6.043 3.060 7.497 1.00 24.33 S ATOM 906 CE MET A 364 5.965 4.818 7.148 1.00 14.93 C ATOM 907 N LEU A 365 7.080 4.380 12.742 1.00 16.66 N ATOM 908 CA LEU A 365 6.741 4.358 14.149 1.00 15.47 C ATOM 909 C LEU A 365 7.393 5.555 14.840 1.00 14.73 C ATOM 910 O LEU A 365 8.606 5.568 15.037 1.00 17.35 O ATOM 911 CB LEU A 365 7.202 3.055 14.794 1.00 14.79 C ATOM 912 CG LEU A 365 6.852 2.894 16.274 1.00 17.75 C ATOM 913 CD1 LEU A 365 5.364 2.651 16.485 1.00 18.74 C ATOM 914 CD2 LEU A 365 7.684 1.793 16.906 1.00 19.14 C ATOM 915 N PRO A 366 6.599 6.560 15.228 1.00 15.53 N ATOM 916 CA PRO A 366 7.186 7.794 15.768 1.00 17.54 C ATOM 917 C PRO A 366 8.024 7.588 17.027 1.00 21.17 C ATOM 918 O PRO A 366 8.896 8.417 17.311 1.00 14.48 O ATOM 919 CB PRO A 366 5.962 8.661 16.077 1.00 21.97 C ATOM 920 CG PRO A 366 4.865 8.091 15.226 1.00 18.45 C ATOM 921 CD PRO A 366 5.126 6.625 15.178 1.00 15.56 C ATOM 922 N GLU A 367 7.783 6.502 17.756 1.00 14.70 N ATOM 923 CA GLU A 367 8.580 6.217 18.948 1.00 18.96 C ATOM 924 C GLU A 367 9.909 5.505 18.657 1.00 18.26 C ATOM 925 O GLU A 367 10.720 5.308 19.568 1.00 17.72 O ATOM 926 CB GLU A 367 7.768 5.379 19.930 1.00 21.32 C ATOM 927 CG GLU A 367 6.606 6.135 20.583 1.00 18.78 C ATOM 928 CD GLU A 367 5.336 6.112 19.758 1.00 22.46 C ATOM 929 OE1 GLU A 367 5.326 5.458 18.701 1.00 18.85 O ATOM 930 OE2 GLU A 367 4.341 6.742 20.167 1.00 23.76 O ATOM 931 N ALA A 368 10.145 5.115 17.403 1.00 13.50 N ATOM 932 CA ALA A 368 11.317 4.302 17.080 1.00 15.02 C ATOM 933 C ALA A 368 12.622 4.979 17.533 1.00 11.02 C ATOM 934 O ALA A 368 12.809 6.197 17.382 1.00 14.05 O ATOM 935 CB ALA A 368 11.372 3.994 15.575 1.00 14.47 C ATOM 936 N ILE A 369 13.510 4.176 18.092 1.00 12.86 N ATOM 937 CA ILE A 369 14.747 4.675 18.666 1.00 13.18 C ATOM 938 C ILE A 369 15.932 4.011 18.019 1.00 15.86 C ATOM 939 O ILE A 369 15.869 2.854 17.596 1.00 15.31 O ATOM 940 CB ILE A 369 14.799 4.442 20.192 1.00 17.93 C ATOM 941 CG1 ILE A 369 14.734 2.934 20.508 1.00 18.35 C ATOM 942 CG2 ILE A 369 13.676 5.225 20.874 1.00 16.86 C ATOM 943 CD1 ILE A 369 14.994 2.578 21.965 1.00 22.31 C ATOM 944 N ALA A 370 17.024 4.758 17.937 1.00 15.08 N ATOM 945 CA ALA A 370 18.276 4.203 17.460 1.00 17.06 C ATOM 946 C ALA A 370 19.295 4.238 18.610 1.00 21.10 C ATOM 947 O ALA A 370 19.597 5.311 19.139 1.00 20.25 O ATOM 948 CB ALA A 370 18.772 4.981 16.236 1.00 15.80 C ATOM 949 N ILE A 371 19.786 3.064 19.017 1.00 19.07 N ATOM 950 CA ILE A 371 20.847 2.964 20.027 1.00 21.61 C ATOM 951 C ILE A 371 22.218 2.820 19.358 1.00 23.33 C ATOM 952 O ILE A 371 22.402 1.970 18.486 1.00 22.32 O ATOM 953 CB ILE A 371 20.623 1.754 20.988 1.00 20.54 C ATOM 954 CG1 ILE A 371 19.231 1.793 21.600 1.00 22.53 C ATOM 955 CG2 ILE A 371 21.641 1.740 22.127 1.00 23.15 C ATOM 956 CD1 ILE A 371 18.966 0.614 22.546 1.00 27.68 C ATOM 957 N VAL A 372 23.184 3.647 19.758 1.00 22.30 N ATOM 958 CA VAL A 372 24.535 3.505 19.238 1.00 21.25 C ATOM 959 C VAL A 372 25.527 3.242 20.387 1.00 27.19 C ATOM 960 O VAL A 372 25.548 3.976 21.379 1.00 23.07 O ATOM 961 CB VAL A 372 24.956 4.752 18.438 1.00 25.22 C ATOM 962 CG1 VAL A 372 26.352 4.574 17.887 1.00 25.70 C ATOM 963 CG2 VAL A 372 23.939 5.015 17.292 1.00 19.31 C ATOM 964 N MET A 373 26.319 2.177 20.257 1.00 20.94 N ATOM 965 CA MET A 373 27.316 1.834 21.273 1.00 30.93 C ATOM 966 C MET A 373 28.711 2.206 20.782 1.00 30.50 C ATOM 967 O MET A 373 29.065 1.932 19.631 1.00 27.14 O ATOM 968 CB MET A 373 27.288 0.340 21.631 1.00 30.41 C ATOM 969 CG MET A 373 25.917 -0.287 21.870 1.00 21.52 C ATOM 970 SD MET A 373 25.028 0.277 23.315 1.00 26.88 S ATOM 971 CE MET A 373 26.125 -0.262 24.638 1.00 29.32 C ATOM 972 N ALA A 374 29.492 2.838 21.654 1.00 34.57 N ATOM 973 CA ALA A 374 30.898 3.105 21.369 1.00 39.77 C ATOM 974 C ALA A 374 31.777 2.456 22.446 1.00 45.57 C ATOM 975 O ALA A 374 32.160 3.118 23.416 1.00 41.64 O ATOM 976 CB ALA A 374 31.153 4.591 21.297 1.00 36.00 C ATOM 977 N PRO A 375 32.082 1.152 22.282 1.00 42.76 N ATOM 978 CA PRO A 375 32.839 0.369 23.271 1.00 44.24 C ATOM 979 C PRO A 375 34.166 1.027 23.636 1.00 44.30 C ATOM 980 O PRO A 375 34.368 1.335 24.814 1.00 47.95 O ATOM 981 CB PRO A 375 33.065 -0.971 22.562 1.00 40.85 C ATOM 982 CG PRO A 375 31.959 -1.071 21.577 1.00 41.51 C ATOM 983 CD PRO A 375 31.738 0.342 21.099 1.00 41.04 C ATOM 984 N SER A 376 35.016 1.247 22.633 1.00 48.15 N ATOM 985 CA SER A 376 36.279 1.963 22.774 1.00 45.46 C ATOM 986 C SER A 376 36.172 3.230 23.632 1.00 45.96 C ATOM 987 O SER A 376 37.088 3.575 24.379 1.00 43.55 O ATOM 988 CB SER A 376 36.801 2.328 21.381 1.00 42.62 C ATOM 989 OG SER A 376 37.442 3.591 21.384 1.00 50.46 O ATOM 990 N LYS A 377 35.054 3.940 23.511 1.00 49.41 N ATOM 991 CA LYS A 377 34.810 5.154 24.295 1.00 41.97 C ATOM 992 C LYS A 377 34.053 4.864 25.593 1.00 39.68 C ATOM 993 O LYS A 377 33.887 5.743 26.441 1.00 42.36 O ATOM 994 CB LYS A 377 34.034 6.181 23.461 1.00 43.27 C ATOM 995 CG LYS A 377 34.916 7.159 22.710 1.00 46.52 C ATOM 996 CD LYS A 377 35.886 6.458 21.776 1.00 45.04 C ATOM 997 CE LYS A 377 37.098 7.328 21.489 1.00 42.13 C ATOM 998 NZ LYS A 377 38.105 6.595 20.657 1.00 52.25 N ATOM 999 N ASN A 378 33.604 3.624 25.747 1.00 40.67 N ATOM 1000 CA ASN A 378 32.744 3.224 26.866 1.00 42.93 C ATOM 1001 C ASN A 378 31.519 4.130 27.083 1.00 44.33 C ATOM 1002 O ASN A 378 31.085 4.356 28.224 1.00 40.02 O ATOM 1003 CB ASN A 378 33.557 3.140 28.159 1.00 49.53 C ATOM 1004 CG ASN A 378 32.943 2.191 29.158 1.00 45.43 C ATOM 1005 OD1 ASN A 378 32.396 2.609 30.177 1.00 54.24 O ATOM 1006 ND2 ASN A 378 32.988 0.902 28.846 1.00 49.62 N ATOM 1007 N THR A 379 30.972 4.633 25.975 1.00 42.50 N ATOM 1008 CA THR A 379 29.730 5.406 25.969 1.00 41.18 C ATOM 1009 C THR A 379 28.717 4.763 25.035 1.00 39.12 C ATOM 1010 O THR A 379 29.082 4.047 24.090 1.00 34.63 O ATOM 1011 CB THR A 379 29.934 6.860 25.496 1.00 38.12 C ATOM 1012 OG1 THR A 379 30.688 6.862 24.273 1.00 39.98 O ATOM 1013 CG2 THR A 379 30.651 7.693 26.555 1.00 42.51 C ATOM 1014 N SER A 380 27.446 5.039 25.306 1.00 39.29 N ATOM 1015 CA SER A 380 26.359 4.640 24.431 1.00 35.26 C ATOM 1016 C SER A 380 25.340 5.780 24.372 1.00 37.28 C ATOM 1017 O SER A 380 25.331 6.656 25.240 1.00 31.35 O ATOM 1018 CB SER A 380 25.715 3.341 24.929 1.00 26.40 C ATOM 1019 OG SER A 380 24.803 3.575 25.990 1.00 32.18 O ATOM 1020 N GLY A 381 24.488 5.781 23.350 1.00 30.98 N ATOM 1021 CA GLY A 381 23.424 6.764 23.285 1.00 26.55 C ATOM 1022 C GLY A 381 22.156 6.236 22.643 1.00 25.77 C ATOM 1023 O GLY A 381 22.216 5.345 21.800 1.00 25.97 O ATOM 1024 N ILE A 382 21.011 6.777 23.052 1.00 21.70 N ATOM 1025 CA ILE A 382 19.736 6.438 22.434 1.00 22.47 C ATOM 1026 C ILE A 382 19.209 7.689 21.723 1.00 24.44 C ATOM 1027 O ILE A 382 18.983 8.712 22.369 1.00 19.56 O ATOM 1028 CB ILE A 382 18.716 5.923 23.471 1.00 22.45 C ATOM 1029 CG1 ILE A 382 19.288 4.732 24.259 1.00 23.97 C ATOM 1030 CG2 ILE A 382 17.407 5.535 22.794 1.00 18.10 C ATOM 1031 CD1 ILE A 382 18.305 4.152 25.270 1.00 27.81 C ATOM 1032 N PHE A 383 19.023 7.597 20.400 1.00 18.97 N ATOM 1033 CA PHE A 383 18.727 8.760 19.565 1.00 18.92 C ATOM 1034 C PHE A 383 17.426 8.673 18.753 1.00 20.78 C ATOM 1035 O PHE A 383 16.863 7.600 18.545 1.00 17.63 O ATOM 1036 CB PHE A 383 19.871 9.001 18.571 1.00 18.94 C ATOM 1037 CG PHE A 383 21.224 9.194 19.213 1.00 26.59 C ATOM 1038 CD1 PHE A 383 21.521 10.366 19.896 1.00 21.16 C ATOM 1039 CD2 PHE A 383 22.206 8.215 19.097 1.00 23.68 C ATOM 1040 CE1 PHE A 383 22.760 10.562 20.460 1.00 26.61 C ATOM 1041 CE2 PHE A 383 23.446 8.394 19.660 1.00 28.78 C ATOM 1042 CZ PHE A 383 23.732 9.575 20.350 1.00 32.30 C ATOM 1043 N ARG A 384 16.971 9.821 18.271 1.00 16.72 N ATOM 1044 CA ARG A 384 15.881 9.869 17.291 1.00 17.14 C ATOM 1045 C ARG A 384 16.005 11.176 16.521 1.00 19.11 C ATOM 1046 O ARG A 384 16.724 12.096 16.948 1.00 16.26 O ATOM 1047 CB ARG A 384 14.509 9.755 17.965 1.00 14.40 C ATOM 1048 CG ARG A 384 14.326 10.764 19.062 1.00 20.78 C ATOM 1049 CD ARG A 384 12.856 10.920 19.482 1.00 19.79 C ATOM 1050 NE ARG A 384 12.723 12.222 20.099 1.00 34.24 N ATOM 1051 CZ ARG A 384 12.162 13.283 19.536 1.00 26.13 C ATOM 1052 NH1 ARG A 384 11.579 13.198 18.346 1.00 30.98 N ATOM 1053 NH2 ARG A 384 12.143 14.425 20.205 1.00 35.13 N ATOM 1054 N LEU A 385 15.329 11.263 15.388 1.00 14.55 N ATOM 1055 CA LEU A 385 15.418 12.471 14.600 1.00 17.16 C ATOM 1056 C LEU A 385 14.463 13.482 15.176 1.00 18.44 C ATOM 1057 O LEU A 385 13.504 13.116 15.859 1.00 18.64 O ATOM 1058 CB LEU A 385 15.111 12.184 13.133 1.00 16.92 C ATOM 1059 CG LEU A 385 16.261 11.573 12.313 1.00 17.39 C ATOM 1060 CD1 LEU A 385 16.660 10.174 12.766 1.00 14.30 C ATOM 1061 CD2 LEU A 385 15.844 11.545 10.850 1.00 22.88 C ATOM 1062 N LEU A 386 14.727 14.762 14.935 1.00 17.20 N ATOM 1063 CA LEU A 386 13.751 15.772 15.287 1.00 16.69 C ATOM 1064 C LEU A 386 12.478 15.518 14.451 1.00 20.14 C ATOM 1065 O LEU A 386 12.560 15.214 13.265 1.00 18.42 O ATOM 1066 CB LEU A 386 14.309 17.175 15.039 1.00 19.21 C ATOM 1067 CG LEU A 386 15.647 17.504 15.704 1.00 24.07 C ATOM 1068 CD1 LEU A 386 16.190 18.829 15.187 1.00 28.96 C ATOM 1069 CD2 LEU A 386 15.485 17.562 17.197 1.00 24.69 C ATOM 1070 N ASP A 387 11.311 15.659 15.066 1.00 18.00 N ATOM 1071 CA ASP A 387 10.057 15.355 14.395 1.00 20.00 C ATOM 1072 C ASP A 387 9.124 16.563 14.571 1.00 23.89 C ATOM 1073 O ASP A 387 8.672 16.831 15.688 1.00 22.14 O ATOM 1074 CB ASP A 387 9.471 14.056 14.985 1.00 24.58 C ATOM 1075 CG ASP A 387 8.077 13.694 14.421 1.00 27.69 C ATOM 1076 OD1 ASP A 387 7.529 14.455 13.597 1.00 24.10 O ATOM 1077 OD2 ASP A 387 7.540 12.630 14.815 1.00 23.34 O ATOM 1078 N PRO A 388 8.800 17.281 13.470 1.00 26.23 N ATOM 1079 CA PRO A 388 9.002 16.923 12.055 1.00 22.86 C ATOM 1080 C PRO A 388 10.284 17.421 11.354 1.00 20.10 C ATOM 1081 O PRO A 388 10.623 16.873 10.315 1.00 21.35 O ATOM 1082 CB PRO A 388 7.773 17.556 11.383 1.00 23.64 C ATOM 1083 CG PRO A 388 7.525 18.804 12.188 1.00 21.64 C ATOM 1084 CD PRO A 388 8.028 18.536 13.604 1.00 25.00 C ATOM 1085 N GLU A 389 10.997 18.402 11.891 1.00 23.25 N ATOM 1086 CA GLU A 389 12.023 19.082 11.081 1.00 23.50 C ATOM 1087 C GLU A 389 13.183 18.183 10.631 1.00 19.76 C ATOM 1088 O GLU A 389 13.674 18.321 9.515 1.00 21.50 O ATOM 1089 CB GLU A 389 12.573 20.298 11.837 1.00 23.21 C ATOM 1090 CG GLU A 389 11.510 21.333 12.238 1.00 32.87 C ATOM 1091 CD GLU A 389 10.760 20.967 13.529 1.00 44.75 C ATOM 1092 OE1 GLU A 389 11.092 19.926 14.162 1.00 31.44 O ATOM 1093 OE2 GLU A 389 9.844 21.732 13.920 1.00 51.11 O ATOM 1094 N GLY A 390 13.613 17.252 11.475 1.00 18.24 N ATOM 1095 CA GLY A 390 14.754 16.411 11.127 1.00 19.36 C ATOM 1096 C GLY A 390 14.331 15.332 10.135 1.00 20.10 C ATOM 1097 O GLY A 390 15.015 15.067 9.130 1.00 15.55 O ATOM 1098 N LEU A 391 13.198 14.701 10.415 1.00 16.54 N ATOM 1099 CA LEU A 391 12.605 13.782 9.450 1.00 16.94 C ATOM 1100 C LEU A 391 12.476 14.456 8.083 1.00 17.61 C ATOM 1101 O LEU A 391 12.906 13.912 7.068 1.00 17.92 O ATOM 1102 CB LEU A 391 11.238 13.305 9.920 1.00 17.02 C ATOM 1103 CG LEU A 391 11.174 12.609 11.279 1.00 18.24 C ATOM 1104 CD1 LEU A 391 9.700 12.327 11.598 1.00 14.81 C ATOM 1105 CD2 LEU A 391 12.032 11.347 11.311 1.00 13.29 C ATOM 1106 N GLN A 392 11.893 15.647 8.064 1.00 19.80 N ATOM 1107 CA GLN A 392 11.747 16.395 6.812 1.00 23.44 C ATOM 1108 C GLN A 392 13.085 16.543 6.058 1.00 23.11 C ATOM 1109 O GLN A 392 13.181 16.243 4.866 1.00 23.66 O ATOM 1110 CB GLN A 392 11.153 17.766 7.093 1.00 24.42 C ATOM 1111 CG GLN A 392 10.751 18.490 5.822 1.00 36.72 C ATOM 1112 CD GLN A 392 10.221 19.888 6.072 1.00 42.39 C ATOM 1113 OE1 GLN A 392 10.315 20.434 7.192 1.00 46.40 O ATOM 1114 NE2 GLN A 392 9.653 20.478 5.029 1.00 34.27 N ATOM 1115 N THR A 393 14.117 16.980 6.763 1.00 19.67 N ATOM 1116 CA THR A 393 15.429 17.153 6.161 1.00 19.12 C ATOM 1117 C THR A 393 15.927 15.860 5.518 1.00 24.28 C ATOM 1118 O THR A 393 16.356 15.863 4.365 1.00 21.80 O ATOM 1119 CB THR A 393 16.446 17.650 7.192 1.00 23.14 C ATOM 1120 OG1 THR A 393 16.105 18.988 7.572 1.00 25.61 O ATOM 1121 CG2 THR A 393 17.874 17.632 6.619 1.00 18.45 C ATOM 1122 N ILE A 394 15.823 14.738 6.229 1.00 22.54 N ATOM 1123 CA ILE A 394 16.350 13.481 5.710 1.00 15.62 C ATOM 1124 C ILE A 394 15.440 12.924 4.604 1.00 22.24 C ATOM 1125 O ILE A 394 15.922 12.357 3.634 1.00 25.27 O ATOM 1126 CB ILE A 394 16.536 12.468 6.842 1.00 21.00 C ATOM 1127 CG1 ILE A 394 17.528 13.029 7.863 1.00 21.38 C ATOM 1128 CG2 ILE A 394 17.087 11.155 6.309 1.00 22.79 C ATOM 1129 CD1 ILE A 394 18.875 13.452 7.235 1.00 23.71 C ATOM 1130 N VAL A 395 14.130 13.091 4.736 1.00 22.23 N ATOM 1131 CA VAL A 395 13.215 12.701 3.651 1.00 24.76 C ATOM 1132 C VAL A 395 13.559 13.399 2.319 1.00 28.89 C ATOM 1133 O VAL A 395 13.622 12.755 1.274 1.00 26.31 O ATOM 1134 CB VAL A 395 11.742 13.008 4.006 1.00 21.87 C ATOM 1135 CG1 VAL A 395 10.848 12.874 2.758 1.00 25.74 C ATOM 1136 CG2 VAL A 395 11.249 12.081 5.091 1.00 18.45 C ATOM 1137 N LYS A 396 13.795 14.707 2.358 1.00 25.35 N ATOM 1138 CA LYS A 396 14.041 15.458 1.133 1.00 29.06 C ATOM 1139 C LYS A 396 15.438 15.200 0.629 1.00 33.07 C ATOM 1140 O LYS A 396 15.743 15.464 -0.533 1.00 39.16 O ATOM 1141 CB LYS A 396 13.860 16.961 1.353 1.00 32.20 C ATOM 1142 CG LYS A 396 12.482 17.379 1.806 1.00 32.50 C ATOM 1143 CD LYS A 396 12.545 18.687 2.618 1.00 39.23 C ATOM 1144 CE LYS A 396 12.936 19.908 1.779 1.00 49.27 C ATOM 1145 NZ LYS A 396 11.786 20.513 1.013 1.00 47.48 N ATOM 1146 N CYS A 397 16.299 14.706 1.509 1.00 29.81 N ATOM 1147 CA CYS A 397 17.694 14.538 1.149 1.00 30.42 C ATOM 1148 C CYS A 397 17.824 13.443 0.115 1.00 35.07 C ATOM 1149 O CYS A 397 17.265 12.361 0.271 1.00 39.40 O ATOM 1150 CB CYS A 397 18.551 14.223 2.369 1.00 29.21 C ATOM 1151 SG CYS A 397 20.312 14.042 1.977 1.00 28.93 S ATOM 1152 N ARG A 398 18.552 13.742 -0.954 1.00 40.85 N ATOM 1153 CA ARG A 398 18.759 12.797 -2.045 1.00 41.72 C ATOM 1154 C ARG A 398 20.231 12.782 -2.433 1.00 45.64 C ATOM 1155 O ARG A 398 20.589 12.306 -3.511 1.00 46.01 O ATOM 1156 CB ARG A 398 17.899 13.160 -3.259 1.00 38.22 C ATOM 1157 CG ARG A 398 16.404 13.218 -2.995 1.00 40.48 C ATOM 1158 CD ARG A 398 15.778 11.836 -2.831 1.00 42.54 C ATOM 1159 NE ARG A 398 14.327 11.917 -2.986 1.00 47.99 N ATOM 1160 CZ ARG A 398 13.468 11.946 -1.970 1.00 45.99 C ATOM 1161 NH1 ARG A 398 13.918 11.868 -0.726 1.00 39.23 N ATOM 1162 NH2 ARG A 398 12.161 12.034 -2.194 1.00 39.53 N ATOM 1163 N LYS A 399 21.073 13.334 -1.559 1.00 47.02 N ATOM 1164 CA LYS A 399 22.520 13.247 -1.726 1.00 46.13 C ATOM 1165 C LYS A 399 22.976 11.797 -1.751 1.00 46.08 C ATOM 1166 O LYS A 399 22.734 11.053 -0.801 1.00 45.64 O ATOM 1167 CB LYS A 399 23.250 13.974 -0.599 1.00 37.28 C ATOM 1168 CG LYS A 399 23.233 15.474 -0.670 1.00 38.80 C ATOM 1169 CD LYS A 399 24.099 16.031 0.444 1.00 38.30 C ATOM 1170 CE LYS A 399 24.191 17.539 0.398 1.00 40.83 C ATOM 1171 NZ LYS A 399 24.602 18.102 1.723 1.00 44.96 N ATOM 1172 N PRO A 400 23.617 11.380 -2.851 1.00 49.45 N ATOM 1173 CA PRO A 400 24.365 10.123 -2.806 1.00 46.59 C ATOM 1174 C PRO A 400 25.598 10.315 -1.937 1.00 50.22 C ATOM 1175 O PRO A 400 26.045 11.455 -1.766 1.00 54.98 O ATOM 1176 CB PRO A 400 24.739 9.877 -4.272 1.00 52.32 C ATOM 1177 CG PRO A 400 24.757 11.253 -4.884 1.00 50.55 C ATOM 1178 CD PRO A 400 23.646 11.998 -4.189 1.00 48.48 C ATOM 1179 N GLY A 401 26.141 9.238 -1.387 1.00 45.76 N ATOM 1180 CA GLY A 401 27.344 9.367 -0.585 1.00 51.99 C ATOM 1181 C GLY A 401 27.097 8.954 0.848 1.00 56.60 C ATOM 1182 O GLY A 401 26.265 9.541 1.540 1.00 56.23 O ATOM 1183 N LEU A 402 27.840 7.949 1.295 1.00 54.19 N ATOM 1184 CA LEU A 402 27.570 7.295 2.563 1.00 50.96 C ATOM 1185 C LEU A 402 27.765 8.193 3.790 1.00 51.06 C ATOM 1186 O LEU A 402 27.052 8.053 4.780 1.00 47.13 O ATOM 1187 CB LEU A 402 28.457 6.058 2.692 1.00 51.86 C ATOM 1188 CG LEU A 402 27.779 4.827 3.277 1.00 51.61 C ATOM 1189 CD1 LEU A 402 26.444 4.570 2.564 1.00 54.92 C ATOM 1190 CD2 LEU A 402 28.707 3.647 3.126 1.00 53.16 C ATOM 1191 N PHE A 403 28.722 9.112 3.734 1.00 42.90 N ATOM 1192 CA PHE A 403 29.067 9.869 4.933 1.00 48.20 C ATOM 1193 C PHE A 403 28.912 11.360 4.705 1.00 47.33 C ATOM 1194 O PHE A 403 29.639 12.172 5.279 1.00 53.97 O ATOM 1195 CB PHE A 403 30.490 9.533 5.379 1.00 53.33 C ATOM 1196 CG PHE A 403 30.658 8.100 5.797 1.00 57.06 C ATOM 1197 CD1 PHE A 403 30.885 7.106 4.850 1.00 55.12 C ATOM 1198 CD2 PHE A 403 30.540 7.738 7.132 1.00 60.91 C ATOM 1199 CE1 PHE A 403 31.023 5.781 5.230 1.00 55.52 C ATOM 1200 CE2 PHE A 403 30.678 6.413 7.526 1.00 59.79 C ATOM 1201 CZ PHE A 403 30.919 5.433 6.573 1.00 57.96 C ATOM 1202 N HIS A 404 27.949 11.711 3.864 1.00 43.60 N ATOM 1203 CA HIS A 404 27.733 13.095 3.499 1.00 42.21 C ATOM 1204 C HIS A 404 27.142 13.878 4.668 1.00 42.81 C ATOM 1205 O HIS A 404 26.464 13.302 5.514 1.00 39.83 O ATOM 1206 CB HIS A 404 26.814 13.175 2.279 1.00 40.90 C ATOM 1207 CG HIS A 404 25.432 12.654 2.524 1.00 40.18 C ATOM 1208 ND1 HIS A 404 24.996 11.442 2.030 1.00 39.33 N ATOM 1209 CD2 HIS A 404 24.388 13.181 3.205 1.00 36.64 C ATOM 1210 CE1 HIS A 404 23.742 11.246 2.396 1.00 39.25 C ATOM 1211 NE2 HIS A 404 23.350 12.286 3.115 1.00 38.35 N ATOM 1212 N PRO A 405 27.378 15.200 4.711 1.00 41.90 N ATOM 1213 CA PRO A 405 26.792 16.010 5.780 1.00 35.92 C ATOM 1214 C PRO A 405 25.371 16.456 5.469 1.00 34.54 C ATOM 1215 O PRO A 405 24.934 16.440 4.319 1.00 33.67 O ATOM 1216 CB PRO A 405 27.720 17.217 5.837 1.00 38.88 C ATOM 1217 CG PRO A 405 28.110 17.412 4.410 1.00 36.38 C ATOM 1218 CD PRO A 405 28.207 16.018 3.807 1.00 40.50 C ATOM 1219 N HIS A 406 24.658 16.847 6.513 1.00 33.64 N ATOM 1220 CA HIS A 406 23.355 17.466 6.376 1.00 31.66 C ATOM 1221 C HIS A 406 23.470 18.836 6.998 1.00 36.03 C ATOM 1222 O HIS A 406 24.337 19.064 7.839 1.00 40.49 O ATOM 1223 CB HIS A 406 22.267 16.626 7.050 1.00 27.35 C ATOM 1224 CG HIS A 406 22.055 15.306 6.387 1.00 26.64 C ATOM 1225 ND1 HIS A 406 22.711 14.162 6.774 1.00 26.35 N ATOM 1226 CD2 HIS A 406 21.303 14.966 5.312 1.00 33.65 C ATOM 1227 CE1 HIS A 406 22.359 13.165 5.985 1.00 25.63 C ATOM 1228 NE2 HIS A 406 21.510 13.626 5.086 1.00 28.00 N ATOM 1229 N GLU A 407 22.627 19.768 6.593 1.00 36.13 N ATOM 1230 CA GLU A 407 22.711 21.063 7.234 1.00 42.76 C ATOM 1231 C GLU A 407 21.543 21.236 8.191 1.00 39.04 C ATOM 1232 O GLU A 407 20.423 20.796 7.920 1.00 40.23 O ATOM 1233 CB GLU A 407 22.763 22.189 6.202 1.00 51.01 C ATOM 1234 CG GLU A 407 21.424 22.807 5.839 1.00 55.31 C ATOM 1235 CD GLU A 407 21.583 24.236 5.359 1.00 65.40 C ATOM 1236 OE1 GLU A 407 22.700 24.593 4.918 1.00 75.61 O ATOM 1237 OE2 GLU A 407 20.605 25.006 5.443 1.00 61.01 O ATOM 1238 N GLY A 408 21.827 21.865 9.325 1.00 36.59 N ATOM 1239 CA GLY A 408 20.831 22.077 10.348 1.00 37.27 C ATOM 1240 C GLY A 408 20.873 20.947 11.345 1.00 36.18 C ATOM 1241 O GLY A 408 21.507 19.914 11.100 1.00 34.34 O ATOM 1242 N LYS A 409 20.214 21.149 12.479 1.00 30.75 N ATOM 1243 CA LYS A 409 20.112 20.109 13.484 1.00 30.34 C ATOM 1244 C LYS A 409 19.114 19.063 12.971 1.00 29.29 C ATOM 1245 O LYS A 409 18.037 19.413 12.476 1.00 34.82 O ATOM 1246 CB LYS A 409 19.675 20.702 14.828 1.00 34.23 C ATOM 1247 CG LYS A 409 19.688 19.724 15.996 1.00 36.50 C ATOM 1248 CD LYS A 409 19.180 20.389 17.283 1.00 35.37 C ATOM 1249 CE LYS A 409 18.806 19.361 18.351 1.00 35.35 C ATOM 1250 NZ LYS A 409 19.953 18.467 18.710 1.00 34.03 N ATOM 1251 N VAL A 410 19.476 17.788 13.069 1.00 24.54 N ATOM 1252 CA VAL A 410 18.676 16.718 12.482 1.00 24.05 C ATOM 1253 C VAL A 410 18.200 15.716 13.532 1.00 23.23 C ATOM 1254 O VAL A 410 17.073 15.205 13.461 1.00 17.69 O ATOM 1255 CB VAL A 410 19.484 15.985 11.380 1.00 22.88 C ATOM 1256 CG1 VAL A 410 18.806 14.671 10.983 1.00 18.91 C ATOM 1257 CG2 VAL A 410 19.657 16.890 10.156 1.00 22.66 C ATOM 1258 N TYR A 411 19.055 15.429 14.511 1.00 22.37 N ATOM 1259 CA TYR A 411 18.690 14.467 15.538 1.00 20.78 C ATOM 1260 C TYR A 411 19.016 14.964 16.948 1.00 26.51 C ATOM 1261 O TYR A 411 19.590 16.048 17.134 1.00 22.21 O ATOM 1262 CB TYR A 411 19.356 13.118 15.264 1.00 19.79 C ATOM 1263 CG TYR A 411 20.843 13.047 15.514 1.00 20.49 C ATOM 1264 CD1 TYR A 411 21.757 13.476 14.553 1.00 19.84 C ATOM 1265 CD2 TYR A 411 21.335 12.520 16.706 1.00 21.23 C ATOM 1266 CE1 TYR A 411 23.128 13.390 14.777 1.00 21.99 C ATOM 1267 CE2 TYR A 411 22.697 12.427 16.944 1.00 23.44 C ATOM 1268 CZ TYR A 411 23.591 12.872 15.991 1.00 23.60 C ATOM 1269 OH TYR A 411 24.935 12.779 16.252 1.00 25.54 O ATOM 1270 N THR A 412 18.608 14.165 17.929 1.00 19.36 N ATOM 1271 CA THR A 412 18.664 14.529 19.334 1.00 19.62 C ATOM 1272 C THR A 412 18.692 13.246 20.160 1.00 24.76 C ATOM 1273 O THR A 412 18.350 12.178 19.664 1.00 21.87 O ATOM 1274 CB THR A 412 17.466 15.393 19.744 1.00 25.07 C ATOM 1275 OG1 THR A 412 17.605 15.823 21.103 1.00 25.97 O ATOM 1276 CG2 THR A 412 16.143 14.613 19.587 1.00 22.42 C ATOM 1277 N MET A 413 19.102 13.348 21.415 1.00 22.06 N ATOM 1278 CA MET A 413 19.053 12.215 22.321 1.00 21.40 C ATOM 1279 C MET A 413 17.647 12.041 22.804 1.00 22.99 C ATOM 1280 O MET A 413 16.976 13.032 23.049 1.00 24.60 O ATOM 1281 CB MET A 413 19.968 12.431 23.524 1.00 26.61 C ATOM 1282 CG MET A 413 21.385 11.962 23.343 1.00 35.98 C ATOM 1283 SD MET A 413 22.262 12.099 24.917 1.00 47.10 S ATOM 1284 CE MET A 413 21.041 11.520 26.097 1.00 29.76 C ATOM 1285 N VAL A 414 17.190 10.803 22.958 1.00 24.75 N ATOM 1286 CA VAL A 414 15.840 10.610 23.469 1.00 28.80 C ATOM 1287 C VAL A 414 15.881 11.008 24.904 1.00 31.82 C ATOM 1288 O VAL A 414 16.902 10.864 25.583 1.00 33.59 O ATOM 1289 CB VAL A 414 15.283 9.150 23.350 1.00 28.77 C ATOM 1290 CG1 VAL A 414 15.419 8.624 21.938 1.00 24.27 C ATOM 1291 CG2 VAL A 414 15.931 8.230 24.359 1.00 35.78 C ATOM 1292 N ALA A 415 14.788 11.574 25.367 1.00 27.45 N ATOM 1293 CA ALA A 415 14.742 11.935 26.752 1.00 40.39 C ATOM 1294 C ALA A 415 14.349 10.673 27.542 1.00 43.89 C ATOM 1295 O ALA A 415 13.411 9.935 27.179 1.00 44.00 O ATOM 1296 CB ALA A 415 13.787 13.083 26.967 1.00 42.66 C ATOM 1297 N GLN A 416 15.140 10.385 28.570 1.00 46.24 N ATOM 1298 CA GLN A 416 14.865 9.288 29.493 1.00 43.17 C ATOM 1299 C GLN A 416 14.588 9.961 30.829 1.00 48.37 C ATOM 1300 O GLN A 416 15.192 11.015 31.116 1.00 41.07 O ATOM 1301 CB GLN A 416 16.041 8.302 29.579 1.00 36.65 C ATOM 1302 CG GLN A 416 16.502 7.744 28.225 1.00 39.34 C ATOM 1303 CD GLN A 416 17.554 6.641 28.350 1.00 47.72 C ATOM 1304 OE1 GLN A 416 17.285 5.563 28.892 1.00 50.08 O ATOM 1305 NE2 GLN A 416 18.755 6.906 27.837 1.00 39.44 N ATOM 1306 N PRO A 417 13.674 9.404 31.631 1.00 45.70 N ATOM 1307 CA PRO A 417 12.963 8.155 31.339 1.00 36.97 C ATOM 1308 C PRO A 417 11.578 8.394 30.747 1.00 41.35 C ATOM 1309 O PRO A 417 10.651 7.615 31.000 1.00 53.23 O ATOM 1310 CB PRO A 417 12.834 7.317 32.612 1.00 41.74 C ATOM 1311 N GLY A 418 11.429 9.459 29.962 1.00 43.46 N ATOM 1312 CA GLY A 418 10.119 9.844 29.472 1.00 40.95 C ATOM 1313 C GLY A 418 9.622 9.069 28.276 1.00 36.11 C ATOM 1314 O GLY A 418 8.532 8.493 28.271 1.00 48.09 O ATOM 1315 N HIS A 419 10.423 9.087 27.232 1.00 33.41 N ATOM 1316 CA HIS A 419 10.111 8.339 26.044 1.00 32.79 C ATOM 1317 C HIS A 419 10.605 6.897 26.272 1.00 32.11 C ATOM 1318 O HIS A 419 9.824 5.943 26.229 1.00 32.59 O ATOM 1319 CB HIS A 419 10.759 9.031 24.834 1.00 36.92 C ATOM 1320 CG HIS A 419 10.663 8.267 23.555 1.00 27.59 C ATOM 1321 ND1 HIS A 419 11.449 8.565 22.465 1.00 24.81 N ATOM 1322 CD2 HIS A 419 9.885 7.217 23.191 1.00 26.85 C ATOM 1323 CE1 HIS A 419 11.166 7.726 21.484 1.00 23.60 C ATOM 1324 NE2 HIS A 419 10.227 6.891 21.900 1.00 21.10 N ATOM 1325 N VAL A 420 11.889 6.751 26.567 1.00 27.46 N ATOM 1326 CA VAL A 420 12.471 5.450 26.834 1.00 26.61 C ATOM 1327 C VAL A 420 12.832 5.262 28.317 1.00 35.82 C ATOM 1328 O VAL A 420 13.676 5.986 28.849 1.00 36.76 O ATOM 1329 CB VAL A 420 13.724 5.238 25.963 1.00 26.62 C ATOM 1330 CG1 VAL A 420 14.542 4.055 26.443 1.00 25.90 C ATOM 1331 CG2 VAL A 420 13.303 5.041 24.516 1.00 27.89 C ATOM 1332 N ARG A 421 12.195 4.291 28.976 1.00 31.74 N ATOM 1333 CA ARG A 421 12.594 3.901 30.336 1.00 36.97 C ATOM 1334 C ARG A 421 13.270 2.524 30.398 1.00 34.61 C ATOM 1335 O ARG A 421 12.680 1.511 30.014 1.00 33.88 O ATOM 1336 CB ARG A 421 11.396 3.908 31.276 1.00 37.87 C ATOM 1337 CG ARG A 421 11.745 3.379 32.674 1.00 47.95 C ATOM 1338 CD ARG A 421 10.763 3.879 33.726 1.00 55.14 C ATOM 1339 NE ARG A 421 11.412 4.710 34.741 1.00 66.14 N ATOM 1340 CZ ARG A 421 10.810 5.704 35.392 1.00 64.54 C ATOM 1341 NH1 ARG A 421 11.475 6.406 36.301 1.00 70.72 N ATOM 1342 NH2 ARG A 421 9.543 6.005 35.130 1.00 59.25 N ATOM 1343 N GLU A 422 14.511 2.509 30.881 1.00 38.71 N ATOM 1344 CA GLU A 422 15.293 1.286 31.018 1.00 32.66 C ATOM 1345 C GLU A 422 14.856 0.511 32.254 1.00 41.93 C ATOM 1346 O GLU A 422 15.092 0.961 33.369 1.00 45.76 O ATOM 1347 CB GLU A 422 16.792 1.587 31.124 1.00 36.65 C ATOM 1348 CG GLU A 422 17.334 2.526 30.070 1.00 39.18 C ATOM 1349 CD GLU A 422 18.839 2.399 29.878 1.00 51.60 C ATOM 1350 OE1 GLU A 422 19.468 1.525 30.516 1.00 51.47 O ATOM 1351 OE2 GLU A 422 19.404 3.170 29.072 1.00 55.74 O ATOM 1352 N ILE A 423 14.228 -0.648 32.078 1.00 42.08 N ATOM 1353 CA ILE A 423 13.844 -1.457 33.228 1.00 39.65 C ATOM 1354 C ILE A 423 14.529 -2.814 33.342 1.00 47.86 C ATOM 1355 O ILE A 423 15.478 -3.163 32.637 1.00 47.00 O ATOM 1356 CB ILE A 423 12.324 -1.661 33.255 1.00 35.30 C ATOM 1357 CG1 ILE A 423 11.874 -2.608 32.138 1.00 39.30 C ATOM 1358 CG2 ILE A 423 11.637 -0.303 33.181 1.00 43.17 C ATOM 1359 CD1 ILE A 423 10.351 -2.687 32.002 1.00 32.87 C ATOM 1360 N ASN A 424 13.945 -3.569 34.249 1.00 47.53 N ATOM 1361 CA ASN A 424 14.496 -4.733 34.947 1.00 50.96 C ATOM 1362 C ASN A 424 13.634 -5.941 34.602 1.00 49.11 C ATOM 1363 O ASN A 424 12.874 -6.448 35.443 1.00 50.68 O ATOM 1364 CB ASN A 424 14.524 -4.319 36.430 1.00 53.98 C ATOM 1365 CG ASN A 424 15.936 -4.139 36.989 1.00 60.65 C ATOM 1366 OD1 ASN A 424 16.413 -3.006 37.259 1.00 60.87 O ATOM 1367 ND2 ASN A 424 16.463 -5.279 37.463 1.00 70.55 N ATOM 1368 N SER A 425 13.673 -6.268 33.300 1.00 40.11 N ATOM 1369 CA SER A 425 12.748 -7.209 32.657 1.00 40.00 C ATOM 1370 C SER A 425 13.514 -8.205 31.782 1.00 38.97 C ATOM 1371 O SER A 425 14.728 -8.071 31.605 1.00 36.82 O ATOM 1372 CB SER A 425 11.712 -6.469 31.802 1.00 40.59 C ATOM 1373 OG SER A 425 12.400 -5.796 30.752 1.00 44.20 O ATOM 1374 N LYS A 426 12.794 -9.176 31.212 1.00 36.45 N ATOM 1375 CA LYS A 426 13.423 -10.288 30.493 1.00 39.72 C ATOM 1376 C LYS A 426 13.910 -9.837 29.112 1.00 40.27 C ATOM 1377 O LYS A 426 13.702 -8.690 28.721 1.00 39.47 O ATOM 1378 CB LYS A 426 12.452 -11.482 30.374 1.00 32.08 C ATOM 1379 CG LYS A 426 11.031 -11.113 29.939 1.00 35.54 C ATOM 1380 CD LYS A 426 10.100 -12.329 29.940 1.00 29.96 C ATOM 1381 CE LYS A 426 8.651 -11.885 29.903 1.00 35.84 C ATOM 1382 NZ LYS A 426 7.649 -12.957 29.591 1.00 33.67 N ATOM 1383 N LEU A 427 14.565 -10.748 28.395 1.00 40.03 N ATOM 1384 CA LEU A 427 15.108 -10.491 27.065 1.00 30.57 C ATOM 1385 C LEU A 427 15.493 -11.800 26.392 1.00 36.49 C ATOM 1386 O LEU A 427 16.280 -12.578 26.944 1.00 34.37 O ATOM 1387 CB LEU A 427 16.338 -9.594 27.129 1.00 31.52 C ATOM 1388 CG LEU A 427 16.949 -9.276 25.760 1.00 30.88 C ATOM 1389 CD1 LEU A 427 15.983 -8.407 24.976 1.00 26.68 C ATOM 1390 CD2 LEU A 427 18.332 -8.630 25.862 1.00 29.86 C ATOM 1391 N GLN A 428 14.933 -12.032 25.209 1.00 32.31 N ATOM 1392 CA GLN A 428 15.417 -13.066 24.299 1.00 35.04 C ATOM 1393 C GLN A 428 16.356 -12.455 23.245 1.00 34.69 C ATOM 1394 O GLN A 428 16.109 -11.358 22.742 1.00 31.00 O ATOM 1395 CB GLN A 428 14.247 -13.755 23.604 1.00 30.84 C ATOM 1396 CG GLN A 428 13.661 -14.989 24.303 1.00 40.95 C ATOM 1397 CD GLN A 428 12.356 -15.447 23.646 1.00 42.51 C ATOM 1398 OE1 GLN A 428 11.387 -14.687 23.578 1.00 48.96 O ATOM 1399 NE2 GLN A 428 12.329 -16.674 23.153 1.00 33.61 N ATOM 1400 N VAL A 429 17.435 -13.155 22.913 1.00 36.96 N ATOM 1401 CA VAL A 429 18.289 -12.744 21.805 1.00 26.78 C ATOM 1402 C VAL A 429 18.159 -13.779 20.693 1.00 32.69 C ATOM 1403 O VAL A 429 18.451 -14.949 20.906 1.00 33.38 O ATOM 1404 CB VAL A 429 19.756 -12.607 22.209 1.00 32.96 C ATOM 1405 CG1 VAL A 429 20.590 -12.203 21.004 1.00 26.33 C ATOM 1406 CG2 VAL A 429 19.921 -11.603 23.339 1.00 30.33 C ATOM 1407 N VAL A 430 17.695 -13.340 19.526 1.00 27.26 N ATOM 1408 CA VAL A 430 17.563 -14.190 18.345 1.00 29.13 C ATOM 1409 C VAL A 430 18.676 -13.906 17.307 1.00 34.93 C ATOM 1410 O VAL A 430 18.649 -12.877 16.627 1.00 27.79 O ATOM 1411 CB VAL A 430 16.191 -13.988 17.693 1.00 26.72 C ATOM 1412 CG1 VAL A 430 15.924 -15.050 16.621 1.00 28.73 C ATOM 1413 CG2 VAL A 430 15.114 -14.024 18.753 1.00 25.94 C ATOM 1414 N ASP A 431 19.647 -14.815 17.187 1.00 31.65 N ATOM 1415 CA ASP A 431 20.743 -14.648 16.240 1.00 30.04 C ATOM 1416 C ASP A 431 20.493 -15.390 14.932 1.00 32.11 C ATOM 1417 O ASP A 431 20.582 -16.608 14.880 1.00 34.03 O ATOM 1418 CB ASP A 431 22.048 -15.122 16.859 1.00 29.23 C ATOM 1419 CG ASP A 431 23.251 -14.742 16.034 1.00 29.19 C ATOM 1420 OD1 ASP A 431 23.086 -14.267 14.886 1.00 30.33 O ATOM 1421 OD2 ASP A 431 24.377 -14.940 16.529 1.00 33.10 O ATOM 1422 N LEU A 432 20.205 -14.637 13.874 1.00 34.02 N ATOM 1423 CA LEU A 432 19.868 -15.203 12.572 1.00 29.34 C ATOM 1424 C LEU A 432 21.073 -15.334 11.633 1.00 33.51 C ATOM 1425 O LEU A 432 20.922 -15.756 10.485 1.00 34.17 O ATOM 1426 CB LEU A 432 18.799 -14.348 11.886 1.00 29.99 C ATOM 1427 CG LEU A 432 17.516 -14.030 12.650 1.00 27.34 C ATOM 1428 CD1 LEU A 432 16.665 -13.052 11.840 1.00 24.55 C ATOM 1429 CD2 LEU A 432 16.757 -15.303 12.929 1.00 28.63 C ATOM 1430 N ARG A 433 22.258 -14.965 12.112 1.00 31.83 N ATOM 1431 CA ARG A 433 23.468 -15.023 11.292 1.00 32.97 C ATOM 1432 C ARG A 433 23.908 -16.457 11.025 1.00 35.65 C ATOM 1433 O ARG A 433 23.534 -17.377 11.757 1.00 39.73 O ATOM 1434 CB ARG A 433 24.598 -14.258 11.968 1.00 28.86 C ATOM 1435 CG ARG A 433 24.287 -12.795 12.213 1.00 27.57 C ATOM 1436 CD ARG A 433 25.404 -12.118 12.991 1.00 28.72 C ATOM 1437 NE ARG A 433 25.543 -12.608 14.365 1.00 30.47 N ATOM 1438 CZ ARG A 433 26.476 -12.163 15.199 1.00 27.04 C ATOM 1439 NH1 ARG A 433 27.336 -11.251 14.779 1.00 30.85 N ATOM 1440 NH2 ARG A 433 26.566 -12.628 16.436 1.00 27.22 N TER 1441 ARG A 433 ATOM 1442 N MET B 1 -7.027 0.921 -8.708 1.00 35.45 N ATOM 1443 CA MET B 1 -7.381 0.014 -7.621 1.00 34.64 C ATOM 1444 C MET B 1 -6.519 0.306 -6.395 1.00 34.48 C ATOM 1445 O MET B 1 -5.396 0.787 -6.525 1.00 38.08 O ATOM 1446 CB MET B 1 -7.215 -1.452 -8.052 1.00 35.93 C ATOM 1447 CG MET B 1 -5.775 -1.885 -8.325 1.00 38.19 C ATOM 1448 SD MET B 1 -5.619 -3.608 -8.845 1.00 33.75 S ATOM 1449 CE MET B 1 -3.843 -3.857 -8.803 1.00 33.00 C ATOM 1450 N GLN B 2 -7.044 0.016 -5.213 1.00 32.20 N ATOM 1451 CA GLN B 2 -6.279 0.175 -3.983 1.00 36.57 C ATOM 1452 C GLN B 2 -5.577 -1.107 -3.597 1.00 37.58 C ATOM 1453 O GLN B 2 -6.136 -2.206 -3.730 1.00 32.13 O ATOM 1454 CB GLN B 2 -7.172 0.598 -2.820 1.00 33.86 C ATOM 1455 CG GLN B 2 -7.495 2.070 -2.768 1.00 42.54 C ATOM 1456 CD GLN B 2 -8.234 2.429 -1.496 1.00 41.73 C ATOM 1457 OE1 GLN B 2 -8.462 1.574 -0.635 1.00 49.58 O ATOM 1458 NE2 GLN B 2 -8.617 3.690 -1.371 1.00 43.35 N ATOM 1459 N ILE B 3 -4.353 -0.964 -3.105 1.00 29.95 N ATOM 1460 CA ILE B 3 -3.691 -2.065 -2.422 1.00 28.64 C ATOM 1461 C ILE B 3 -3.194 -1.584 -1.073 1.00 25.61 C ATOM 1462 O ILE B 3 -2.950 -0.396 -0.864 1.00 25.39 O ATOM 1463 CB ILE B 3 -2.506 -2.640 -3.226 1.00 26.31 C ATOM 1464 CG1 ILE B 3 -1.437 -1.565 -3.471 1.00 25.28 C ATOM 1465 CG2 ILE B 3 -2.991 -3.261 -4.521 1.00 23.40 C ATOM 1466 CD1 ILE B 3 -0.205 -2.095 -4.186 1.00 21.36 C ATOM 1467 N PHE B 4 -3.053 -2.530 -0.165 1.00 25.82 N ATOM 1468 CA PHE B 4 -2.603 -2.259 1.181 1.00 26.61 C ATOM 1469 C PHE B 4 -1.169 -2.751 1.362 1.00 28.46 C ATOM 1470 O PHE B 4 -0.785 -3.823 0.874 1.00 24.48 O ATOM 1471 CB PHE B 4 -3.541 -2.926 2.197 1.00 32.27 C ATOM 1472 CG PHE B 4 -4.995 -2.599 1.981 1.00 28.25 C ATOM 1473 CD1 PHE B 4 -5.426 -1.277 1.969 1.00 31.42 C ATOM 1474 CD2 PHE B 4 -5.925 -3.612 1.784 1.00 31.42 C ATOM 1475 CE1 PHE B 4 -6.759 -0.965 1.766 1.00 36.31 C ATOM 1476 CE2 PHE B 4 -7.275 -3.309 1.581 1.00 32.75 C ATOM 1477 CZ PHE B 4 -7.692 -1.988 1.568 1.00 28.12 C ATOM 1478 N VAL B 5 -0.376 -1.939 2.048 1.00 28.06 N ATOM 1479 CA VAL B 5 1.001 -2.279 2.371 1.00 21.55 C ATOM 1480 C VAL B 5 1.167 -2.246 3.876 1.00 22.49 C ATOM 1481 O VAL B 5 1.151 -1.184 4.481 1.00 20.70 O ATOM 1482 CB VAL B 5 1.994 -1.302 1.719 1.00 25.52 C ATOM 1483 CG1 VAL B 5 3.443 -1.683 2.079 1.00 21.89 C ATOM 1484 CG2 VAL B 5 1.801 -1.289 0.225 1.00 24.55 C ATOM 1485 N LYS B 6 1.318 -3.419 4.471 1.00 22.65 N ATOM 1486 CA LYS B 6 1.367 -3.559 5.918 1.00 23.22 C ATOM 1487 C LYS B 6 2.812 -3.548 6.403 1.00 24.22 C ATOM 1488 O LYS B 6 3.666 -4.214 5.817 1.00 21.34 O ATOM 1489 CB LYS B 6 0.667 -4.857 6.320 1.00 28.49 C ATOM 1490 CG LYS B 6 0.424 -5.053 7.787 1.00 32.20 C ATOM 1491 CD LYS B 6 -0.670 -6.113 7.989 1.00 44.25 C ATOM 1492 CE LYS B 6 -0.905 -6.431 9.463 1.00 39.38 C ATOM 1493 NZ LYS B 6 0.230 -7.191 10.046 1.00 39.62 N ATOM 1494 N THR B 7 3.091 -2.771 7.449 1.00 20.39 N ATOM 1495 CA THR B 7 4.441 -2.689 8.007 1.00 20.37 C ATOM 1496 C THR B 7 4.589 -3.660 9.164 1.00 20.96 C ATOM 1497 O THR B 7 3.630 -4.328 9.537 1.00 24.40 O ATOM 1498 CB THR B 7 4.776 -1.268 8.514 1.00 19.04 C ATOM 1499 OG1 THR B 7 3.939 -0.971 9.636 1.00 23.72 O ATOM 1500 CG2 THR B 7 4.536 -0.226 7.435 1.00 17.60 C ATOM 1501 N LEU B 8 5.784 -3.720 9.741 1.00 18.38 N ATOM 1502 CA LEU B 8 6.024 -4.489 10.961 1.00 21.46 C ATOM 1503 C LEU B 8 5.943 -3.580 12.184 1.00 21.70 C ATOM 1504 O LEU B 8 6.395 -3.963 13.276 1.00 22.76 O ATOM 1505 CB LEU B 8 7.386 -5.192 10.923 1.00 16.53 C ATOM 1506 CG LEU B 8 7.580 -6.393 9.987 1.00 20.63 C ATOM 1507 CD1 LEU B 8 9.070 -6.677 9.729 1.00 19.01 C ATOM 1508 CD2 LEU B 8 6.898 -7.626 10.580 1.00 21.32 C ATOM 1509 N THR B 9 5.365 -2.391 11.992 1.00 21.06 N ATOM 1510 CA THR B 9 5.148 -1.429 13.079 1.00 22.23 C ATOM 1511 C THR B 9 3.668 -1.186 13.432 1.00 25.61 C ATOM 1512 O THR B 9 3.354 -0.242 14.161 1.00 25.29 O ATOM 1513 CB THR B 9 5.739 -0.045 12.747 1.00 22.78 C ATOM 1514 OG1 THR B 9 5.053 0.490 11.610 1.00 20.89 O ATOM 1515 CG2 THR B 9 7.227 -0.122 12.461 1.00 18.66 C ATOM 1516 N GLY B 10 2.760 -2.005 12.906 1.00 21.55 N ATOM 1517 CA GLY B 10 1.343 -1.812 13.175 1.00 26.55 C ATOM 1518 C GLY B 10 0.706 -0.756 12.295 1.00 29.29 C ATOM 1519 O GLY B 10 -0.388 -0.288 12.580 1.00 35.02 O ATOM 1520 N LYS B 11 1.391 -0.374 11.221 1.00 26.48 N ATOM 1521 CA LYS B 11 0.881 0.638 10.301 1.00 22.79 C ATOM 1522 C LYS B 11 0.480 -0.027 8.985 1.00 30.53 C ATOM 1523 O LYS B 11 1.118 -0.997 8.531 1.00 28.75 O ATOM 1524 CB LYS B 11 1.932 1.731 10.062 1.00 19.79 C ATOM 1525 CG LYS B 11 1.518 2.867 9.147 1.00 25.64 C ATOM 1526 CD LYS B 11 2.683 3.858 8.998 1.00 28.84 C ATOM 1527 CE LYS B 11 2.335 5.057 8.126 1.00 31.62 C ATOM 1528 NZ LYS B 11 1.899 6.272 8.896 1.00 35.85 N ATOM 1529 N THR B 12 -0.585 0.482 8.379 1.00 25.76 N ATOM 1530 CA THR B 12 -1.038 -0.024 7.092 1.00 29.06 C ATOM 1531 C THR B 12 -1.161 1.114 6.093 1.00 30.74 C ATOM 1532 O THR B 12 -1.966 2.016 6.284 1.00 34.09 O ATOM 1533 CB THR B 12 -2.382 -0.747 7.216 1.00 29.80 C ATOM 1534 OG1 THR B 12 -2.219 -1.917 8.034 1.00 30.57 O ATOM 1535 CG2 THR B 12 -2.889 -1.152 5.838 1.00 33.12 C ATOM 1536 N ILE B 13 -0.347 1.075 5.036 1.00 25.49 N ATOM 1537 CA ILE B 13 -0.374 2.095 3.992 1.00 27.41 C ATOM 1538 C ILE B 13 -1.335 1.695 2.866 1.00 29.90 C ATOM 1539 O ILE B 13 -1.341 0.545 2.432 1.00 30.55 O ATOM 1540 CB ILE B 13 1.037 2.313 3.402 1.00 25.91 C ATOM 1541 CG1 ILE B 13 1.993 2.806 4.495 1.00 24.59 C ATOM 1542 CG2 ILE B 13 0.997 3.274 2.232 1.00 23.13 C ATOM 1543 CD1 ILE B 13 3.470 2.427 4.270 1.00 25.01 C ATOM 1544 N THR B 14 -2.139 2.643 2.402 1.00 27.03 N ATOM 1545 CA THR B 14 -3.019 2.423 1.253 1.00 29.03 C ATOM 1546 C THR B 14 -2.483 3.112 0.004 1.00 29.12 C ATOM 1547 O THR B 14 -2.232 4.314 0.017 1.00 35.56 O ATOM 1548 CB THR B 14 -4.442 2.940 1.515 1.00 31.58 C ATOM 1549 OG1 THR B 14 -4.986 2.275 2.654 1.00 27.03 O ATOM 1550 CG2 THR B 14 -5.334 2.665 0.311 1.00 32.90 C ATOM 1551 N LEU B 15 -2.304 2.356 -1.074 1.00 30.52 N ATOM 1552 CA LEU B 15 -1.786 2.919 -2.320 1.00 31.16 C ATOM 1553 C LEU B 15 -2.777 2.783 -3.473 1.00 31.54 C ATOM 1554 O LEU B 15 -3.551 1.825 -3.534 1.00 32.37 O ATOM 1555 CB LEU B 15 -0.471 2.244 -2.720 1.00 29.22 C ATOM 1556 CG LEU B 15 0.791 2.319 -1.856 1.00 32.52 C ATOM 1557 CD1 LEU B 15 1.946 1.607 -2.569 1.00 28.93 C ATOM 1558 CD2 LEU B 15 1.168 3.765 -1.534 1.00 28.19 C ATOM 1559 N GLU B 16 -2.749 3.741 -4.392 1.00 31.77 N ATOM 1560 CA GLU B 16 -3.543 3.633 -5.611 1.00 34.00 C ATOM 1561 C GLU B 16 -2.632 3.215 -6.754 1.00 35.56 C ATOM 1562 O GLU B 16 -1.622 3.863 -7.043 1.00 36.12 O ATOM 1563 CB GLU B 16 -4.254 4.946 -5.944 1.00 34.15 C ATOM 1564 CG GLU B 16 -5.206 4.863 -7.151 1.00 36.06 C ATOM 1565 CD GLU B 16 -6.451 4.002 -6.900 1.00 40.29 C ATOM 1566 OE1 GLU B 16 -7.041 3.521 -7.893 1.00 47.50 O ATOM 1567 OE2 GLU B 16 -6.848 3.806 -5.724 1.00 39.13 O ATOM 1568 N VAL B 17 -3.003 2.119 -7.398 1.00 31.91 N ATOM 1569 CA VAL B 17 -2.151 1.469 -8.381 1.00 36.08 C ATOM 1570 C VAL B 17 -2.956 0.926 -9.565 1.00 33.63 C ATOM 1571 O VAL B 17 -4.189 0.963 -9.584 1.00 34.01 O ATOM 1572 CB VAL B 17 -1.367 0.296 -7.748 1.00 30.58 C ATOM 1573 CG1 VAL B 17 -0.340 0.796 -6.723 1.00 28.17 C ATOM 1574 CG2 VAL B 17 -2.331 -0.694 -7.119 1.00 28.63 C ATOM 1575 N GLU B 18 -2.232 0.413 -10.548 1.00 37.08 N ATOM 1576 CA GLU B 18 -2.823 -0.270 -11.682 1.00 34.01 C ATOM 1577 C GLU B 18 -2.098 -1.600 -11.805 1.00 37.09 C ATOM 1578 O GLU B 18 -0.904 -1.686 -11.468 1.00 31.48 O ATOM 1579 CB GLU B 18 -2.694 0.568 -12.960 1.00 40.23 C ATOM 1580 CG GLU B 18 -3.453 1.904 -12.921 1.00 40.48 C ATOM 1581 CD GLU B 18 -4.973 1.724 -12.821 1.00 43.94 C ATOM 1582 OE1 GLU B 18 -5.634 2.517 -12.119 1.00 43.87 O ATOM 1583 OE2 GLU B 18 -5.507 0.781 -13.437 1.00 46.57 O ATOM 1584 N PRO B 19 -2.810 -2.648 -12.264 1.00 33.58 N ATOM 1585 CA PRO B 19 -2.243 -4.000 -12.283 1.00 30.94 C ATOM 1586 C PRO B 19 -0.949 -4.096 -13.073 1.00 29.95 C ATOM 1587 O PRO B 19 -0.222 -5.075 -12.917 1.00 32.39 O ATOM 1588 CB PRO B 19 -3.350 -4.828 -12.947 1.00 30.57 C ATOM 1589 CG PRO B 19 -4.599 -4.120 -12.580 1.00 28.35 C ATOM 1590 CD PRO B 19 -4.240 -2.653 -12.624 1.00 33.84 C ATOM 1591 N SER B 20 -0.665 -3.088 -13.895 1.00 33.20 N ATOM 1592 CA SER B 20 0.515 -3.100 -14.750 1.00 34.03 C ATOM 1593 C SER B 20 1.676 -2.288 -14.188 1.00 28.29 C ATOM 1594 O SER B 20 2.756 -2.277 -14.776 1.00 29.03 O ATOM 1595 CB SER B 20 0.160 -2.580 -16.148 1.00 33.50 C ATOM 1596 OG SER B 20 -0.371 -1.272 -16.083 1.00 31.96 O ATOM 1597 N ASP B 21 1.463 -1.598 -13.072 1.00 29.63 N ATOM 1598 CA ASP B 21 2.573 -0.895 -12.425 1.00 34.26 C ATOM 1599 C ASP B 21 3.649 -1.915 -12.065 1.00 27.50 C ATOM 1600 O ASP B 21 3.330 -3.038 -11.671 1.00 29.39 O ATOM 1601 CB ASP B 21 2.123 -0.144 -11.170 1.00 29.17 C ATOM 1602 CG ASP B 21 1.151 0.991 -11.469 1.00 34.34 C ATOM 1603 OD1 ASP B 21 1.116 1.487 -12.616 1.00 35.69 O ATOM 1604 OD2 ASP B 21 0.413 1.386 -10.542 1.00 37.90 O ATOM 1605 N THR B 22 4.916 -1.545 -12.224 1.00 30.64 N ATOM 1606 CA THR B 22 6.001 -2.424 -11.780 1.00 26.65 C ATOM 1607 C THR B 22 6.172 -2.323 -10.273 1.00 28.10 C ATOM 1608 O THR B 22 5.673 -1.386 -9.648 1.00 27.23 O ATOM 1609 CB THR B 22 7.356 -2.094 -12.449 1.00 28.97 C ATOM 1610 OG1 THR B 22 7.716 -0.739 -12.163 1.00 26.60 O ATOM 1611 CG2 THR B 22 7.283 -2.293 -13.956 1.00 28.20 C ATOM 1612 N ILE B 23 6.884 -3.284 -9.691 1.00 28.62 N ATOM 1613 CA ILE B 23 7.236 -3.189 -8.280 1.00 27.74 C ATOM 1614 C ILE B 23 8.030 -1.892 -8.056 1.00 25.72 C ATOM 1615 O ILE B 23 7.814 -1.188 -7.082 1.00 25.02 O ATOM 1616 CB ILE B 23 8.008 -4.432 -7.819 1.00 27.61 C ATOM 1617 CG1 ILE B 23 7.077 -5.654 -7.825 1.00 26.08 C ATOM 1618 CG2 ILE B 23 8.608 -4.248 -6.435 1.00 28.98 C ATOM 1619 CD1 ILE B 23 5.747 -5.427 -7.119 1.00 28.52 C ATOM 1620 N GLU B 24 8.895 -1.536 -8.995 1.00 24.34 N ATOM 1621 CA GLU B 24 9.633 -0.281 -8.900 1.00 27.53 C ATOM 1622 C GLU B 24 8.714 0.955 -8.801 1.00 31.13 C ATOM 1623 O GLU B 24 8.960 1.840 -7.965 1.00 27.62 O ATOM 1624 CB GLU B 24 10.569 -0.133 -10.099 1.00 28.19 C ATOM 1625 CG GLU B 24 11.578 0.970 -9.930 1.00 37.08 C ATOM 1626 CD GLU B 24 12.435 1.160 -11.166 1.00 46.41 C ATOM 1627 OE1 GLU B 24 13.547 1.717 -11.032 1.00 53.45 O ATOM 1628 OE2 GLU B 24 11.992 0.760 -12.267 1.00 48.70 O ATOM 1629 N ASN B 25 7.678 1.031 -9.649 1.00 25.51 N ATOM 1630 CA ASN B 25 6.712 2.127 -9.563 1.00 25.19 C ATOM 1631 C ASN B 25 6.069 2.167 -8.182 1.00 24.41 C ATOM 1632 O ASN B 25 5.886 3.233 -7.616 1.00 24.41 O ATOM 1633 CB ASN B 25 5.586 2.015 -10.609 1.00 27.68 C ATOM 1634 CG ASN B 25 6.097 1.784 -12.009 1.00 38.28 C ATOM 1635 OD1 ASN B 25 5.568 0.947 -12.754 1.00 38.09 O ATOM 1636 ND2 ASN B 25 7.134 2.522 -12.385 1.00 46.41 N ATOM 1637 N VAL B 26 5.698 1.004 -7.658 1.00 23.15 N ATOM 1638 CA VAL B 26 5.055 0.938 -6.347 1.00 22.45 C ATOM 1639 C VAL B 26 5.955 1.495 -5.229 1.00 26.69 C ATOM 1640 O VAL B 26 5.480 2.209 -4.338 1.00 22.98 O ATOM 1641 CB VAL B 26 4.648 -0.497 -5.997 1.00 20.79 C ATOM 1642 CG1 VAL B 26 4.221 -0.590 -4.539 1.00 21.39 C ATOM 1643 CG2 VAL B 26 3.495 -0.967 -6.912 1.00 22.61 C ATOM 1644 N LYS B 27 7.249 1.182 -5.279 1.00 21.68 N ATOM 1645 CA LYS B 27 8.163 1.673 -4.250 1.00 22.81 C ATOM 1646 C LYS B 27 8.255 3.180 -4.380 1.00 23.98 C ATOM 1647 O LYS B 27 8.387 3.899 -3.403 1.00 23.05 O ATOM 1648 CB LYS B 27 9.543 1.035 -4.380 1.00 19.71 C ATOM 1649 CG LYS B 27 9.564 -0.457 -4.135 1.00 19.21 C ATOM 1650 CD LYS B 27 10.960 -1.015 -4.253 1.00 18.94 C ATOM 1651 CE LYS B 27 10.998 -2.494 -3.907 1.00 23.95 C ATOM 1652 NZ LYS B 27 12.385 -3.068 -3.876 1.00 27.91 N ATOM 1653 N ALA B 28 8.163 3.654 -5.613 1.00 23.68 N ATOM 1654 CA ALA B 28 8.256 5.075 -5.872 1.00 25.90 C ATOM 1655 C ALA B 28 7.040 5.767 -5.288 1.00 25.90 C ATOM 1656 O ALA B 28 7.127 6.876 -4.758 1.00 28.25 O ATOM 1657 CB ALA B 28 8.371 5.330 -7.363 1.00 24.30 C ATOM 1658 N LYS B 29 5.903 5.094 -5.377 1.00 23.39 N ATOM 1659 CA LYS B 29 4.681 5.599 -4.781 1.00 24.00 C ATOM 1660 C LYS B 29 4.833 5.631 -3.257 1.00 26.09 C ATOM 1661 O LYS B 29 4.438 6.593 -2.596 1.00 27.27 O ATOM 1662 CB LYS B 29 3.483 4.733 -5.180 1.00 28.03 C ATOM 1663 CG LYS B 29 3.014 4.874 -6.627 1.00 30.07 C ATOM 1664 CD LYS B 29 1.864 3.887 -6.909 1.00 36.20 C ATOM 1665 CE LYS B 29 1.342 3.993 -8.345 1.00 34.53 C ATOM 1666 NZ LYS B 29 0.727 5.329 -8.560 1.00 45.67 N ATOM 1667 N ILE B 30 5.401 4.573 -2.699 1.00 22.69 N ATOM 1668 CA ILE B 30 5.609 4.522 -1.262 1.00 20.70 C ATOM 1669 C ILE B 30 6.489 5.681 -0.817 1.00 24.22 C ATOM 1670 O ILE B 30 6.215 6.312 0.213 1.00 24.47 O ATOM 1671 CB ILE B 30 6.217 3.170 -0.843 1.00 21.55 C ATOM 1672 CG1 ILE B 30 5.171 2.071 -1.084 1.00 21.27 C ATOM 1673 CG2 ILE B 30 6.655 3.198 0.623 1.00 20.49 C ATOM 1674 CD1 ILE B 30 5.596 0.685 -0.709 1.00 16.11 C ATOM 1675 N GLN B 31 7.513 6.000 -1.617 1.00 22.97 N ATOM 1676 CA GLN B 31 8.383 7.142 -1.327 1.00 22.17 C ATOM 1677 C GLN B 31 7.633 8.467 -1.374 1.00 24.48 C ATOM 1678 O GLN B 31 7.783 9.294 -0.476 1.00 22.10 O ATOM 1679 CB GLN B 31 9.567 7.215 -2.292 1.00 22.55 C ATOM 1680 CG GLN B 31 10.423 8.471 -2.036 1.00 26.83 C ATOM 1681 CD GLN B 31 11.786 8.426 -2.697 1.00 32.03 C ATOM 1682 OE1 GLN B 31 12.816 8.476 -2.021 1.00 39.84 O ATOM 1683 NE2 GLN B 31 11.804 8.334 -4.023 1.00 28.98 N ATOM 1684 N ASP B 32 6.840 8.678 -2.422 1.00 27.91 N ATOM 1685 CA ASP B 32 6.064 9.923 -2.562 1.00 24.84 C ATOM 1686 C ASP B 32 5.139 10.138 -1.389 1.00 22.35 C ATOM 1687 O ASP B 32 5.009 11.242 -0.887 1.00 26.46 O ATOM 1688 CB ASP B 32 5.211 9.918 -3.837 1.00 29.59 C ATOM 1689 CG ASP B 32 6.037 9.941 -5.101 1.00 33.49 C ATOM 1690 OD1 ASP B 32 7.184 10.425 -5.058 1.00 38.82 O ATOM 1691 OD2 ASP B 32 5.530 9.475 -6.145 1.00 40.35 O ATOM 1692 N LYS B 33 4.482 9.066 -0.967 1.00 24.34 N ATOM 1693 CA LYS B 33 3.453 9.155 0.051 1.00 26.14 C ATOM 1694 C LYS B 33 4.013 9.055 1.484 1.00 25.16 C ATOM 1695 O LYS B 33 3.533 9.748 2.377 1.00 22.17 O ATOM 1696 CB LYS B 33 2.402 8.067 -0.182 1.00 21.79 C ATOM 1697 CG LYS B 33 1.275 8.075 0.847 1.00 28.96 C ATOM 1698 CD LYS B 33 0.093 7.175 0.500 1.00 26.83 C ATOM 1699 CE LYS B 33 -1.036 7.415 1.513 1.00 31.89 C ATOM 1700 NZ LYS B 33 -2.307 6.650 1.284 1.00 37.31 N ATOM 1701 N GLU B 34 5.018 8.202 1.701 1.00 22.80 N ATOM 1702 CA GLU B 34 5.491 7.902 3.061 1.00 21.87 C ATOM 1703 C GLU B 34 6.937 8.344 3.353 1.00 23.76 C ATOM 1704 O GLU B 34 7.388 8.305 4.502 1.00 23.08 O ATOM 1705 CB GLU B 34 5.371 6.404 3.337 1.00 23.20 C ATOM 1706 CG GLU B 34 3.997 5.844 3.141 1.00 25.96 C ATOM 1707 CD GLU B 34 3.009 6.346 4.166 1.00 29.48 C ATOM 1708 OE1 GLU B 34 3.451 6.708 5.277 1.00 26.89 O ATOM 1709 OE2 GLU B 34 1.794 6.372 3.856 1.00 28.96 O ATOM 1710 N GLY B 35 7.670 8.744 2.322 1.00 23.04 N ATOM 1711 CA GLY B 35 9.009 9.282 2.512 1.00 19.56 C ATOM 1712 C GLY B 35 10.132 8.263 2.659 1.00 25.24 C ATOM 1713 O GLY B 35 11.244 8.617 3.062 1.00 21.66 O ATOM 1714 N ILE B 36 9.854 7.003 2.333 1.00 22.28 N ATOM 1715 CA ILE B 36 10.862 5.952 2.393 1.00 19.04 C ATOM 1716 C ILE B 36 11.514 5.747 1.024 1.00 22.08 C ATOM 1717 O ILE B 36 10.821 5.441 0.062 1.00 19.91 O ATOM 1718 CB ILE B 36 10.253 4.611 2.846 1.00 22.00 C ATOM 1719 CG1 ILE B 36 9.477 4.781 4.177 1.00 21.49 C ATOM 1720 CG2 ILE B 36 11.330 3.516 2.868 1.00 17.25 C ATOM 1721 CD1 ILE B 36 8.731 3.526 4.643 1.00 15.22 C ATOM 1722 N PRO B 37 12.851 5.898 0.934 1.00 25.50 N ATOM 1723 CA PRO B 37 13.556 5.723 -0.345 1.00 21.21 C ATOM 1724 C PRO B 37 13.419 4.290 -0.855 1.00 27.01 C ATOM 1725 O PRO B 37 13.511 3.371 -0.051 1.00 21.18 O ATOM 1726 CB PRO B 37 15.017 6.030 -0.001 1.00 27.09 C ATOM 1727 CG PRO B 37 14.977 6.743 1.332 1.00 25.97 C ATOM 1728 CD PRO B 37 13.770 6.215 2.042 1.00 24.40 C ATOM 1729 N PRO B 38 13.176 4.104 -2.171 1.00 27.37 N ATOM 1730 CA PRO B 38 13.002 2.776 -2.770 1.00 21.83 C ATOM 1731 C PRO B 38 14.086 1.778 -2.390 1.00 23.17 C ATOM 1732 O PRO B 38 13.767 0.605 -2.189 1.00 22.45 O ATOM 1733 CB PRO B 38 13.037 3.074 -4.273 1.00 23.03 C ATOM 1734 CG PRO B 38 12.421 4.416 -4.371 1.00 20.72 C ATOM 1735 CD PRO B 38 12.839 5.172 -3.126 1.00 26.19 C ATOM 1736 N ASP B 39 15.333 2.229 -2.264 1.00 23.22 N ATOM 1737 CA ASP B 39 16.447 1.304 -2.040 1.00 24.84 C ATOM 1738 C ASP B 39 16.464 0.772 -0.603 1.00 26.60 C ATOM 1739 O ASP B 39 17.225 -0.133 -0.286 1.00 26.85 O ATOM 1740 CB ASP B 39 17.798 1.966 -2.403 1.00 21.67 C ATOM 1741 CG ASP B 39 18.162 3.144 -1.492 1.00 32.54 C ATOM 1742 OD1 ASP B 39 17.329 3.556 -0.658 1.00 34.37 O ATOM 1743 OD2 ASP B 39 19.289 3.682 -1.623 1.00 38.45 O ATOM 1744 N GLN B 40 15.602 1.310 0.256 1.00 24.84 N ATOM 1745 CA GLN B 40 15.458 0.762 1.603 1.00 23.11 C ATOM 1746 C GLN B 40 14.302 -0.233 1.702 1.00 24.86 C ATOM 1747 O GLN B 40 14.146 -0.922 2.718 1.00 21.39 O ATOM 1748 CB GLN B 40 15.252 1.879 2.605 1.00 21.61 C ATOM 1749 CG GLN B 40 16.476 2.714 2.847 1.00 25.44 C ATOM 1750 CD GLN B 40 16.224 3.741 3.921 1.00 28.59 C ATOM 1751 OE1 GLN B 40 15.301 3.591 4.727 1.00 26.26 O ATOM 1752 NE2 GLN B 40 17.018 4.806 3.928 1.00 27.31 N ATOM 1753 N GLN B 41 13.497 -0.313 0.649 1.00 20.50 N ATOM 1754 CA GLN B 41 12.240 -1.060 0.720 1.00 20.14 C ATOM 1755 C GLN B 41 12.416 -2.471 0.206 1.00 19.89 C ATOM 1756 O GLN B 41 13.067 -2.687 -0.804 1.00 23.79 O ATOM 1757 CB GLN B 41 11.138 -0.364 -0.085 1.00 23.73 C ATOM 1758 CG GLN B 41 10.769 1.060 0.336 1.00 17.06 C ATOM 1759 CD GLN B 41 9.738 1.661 -0.623 1.00 24.69 C ATOM 1760 OE1 GLN B 41 8.844 0.957 -1.098 1.00 21.37 O ATOM 1761 NE2 GLN B 41 9.864 2.960 -0.916 1.00 21.42 N ATOM 1762 N ARG B 42 11.862 -3.429 0.937 1.00 17.70 N ATOM 1763 CA ARG B 42 11.696 -4.797 0.465 1.00 22.49 C ATOM 1764 C ARG B 42 10.207 -5.100 0.614 1.00 24.82 C ATOM 1765 O ARG B 42 9.643 -4.965 1.716 1.00 20.91 O ATOM 1766 CB ARG B 42 12.545 -5.817 1.255 1.00 22.71 C ATOM 1767 CG ARG B 42 13.971 -5.381 1.626 1.00 24.68 C ATOM 1768 CD ARG B 42 14.845 -5.318 0.407 1.00 31.80 C ATOM 1769 NE ARG B 42 16.250 -5.028 0.716 1.00 38.16 N ATOM 1770 CZ ARG B 42 16.904 -3.942 0.310 1.00 28.99 C ATOM 1771 NH1 ARG B 42 16.276 -3.000 -0.394 1.00 30.17 N ATOM 1772 NH2 ARG B 42 18.180 -3.781 0.633 1.00 30.02 N ATOM 1773 N LEU B 43 9.568 -5.460 -0.498 1.00 25.19 N ATOM 1774 CA LEU B 43 8.130 -5.746 -0.520 1.00 23.60 C ATOM 1775 C LEU B 43 7.898 -7.250 -0.638 1.00 28.16 C ATOM 1776 O LEU B 43 8.553 -7.925 -1.424 1.00 28.56 O ATOM 1777 CB LEU B 43 7.447 -5.011 -1.676 1.00 25.57 C ATOM 1778 CG LEU B 43 7.554 -3.492 -1.589 1.00 25.51 C ATOM 1779 CD1 LEU B 43 7.006 -2.812 -2.829 1.00 23.03 C ATOM 1780 CD2 LEU B 43 6.835 -2.994 -0.343 1.00 24.54 C ATOM 1781 N ILE B 44 6.967 -7.768 0.150 1.00 27.15 N ATOM 1782 CA ILE B 44 6.736 -9.202 0.202 1.00 25.85 C ATOM 1783 C ILE B 44 5.261 -9.491 0.033 1.00 30.05 C ATOM 1784 O ILE B 44 4.424 -8.856 0.667 1.00 28.63 O ATOM 1785 CB ILE B 44 7.229 -9.815 1.530 1.00 24.19 C ATOM 1786 CG1 ILE B 44 8.742 -9.635 1.655 1.00 26.77 C ATOM 1787 CG2 ILE B 44 6.825 -11.286 1.641 1.00 23.03 C ATOM 1788 CD1 ILE B 44 9.340 -10.353 2.826 1.00 29.43 C ATOM 1789 N PHE B 45 4.946 -10.442 -0.839 1.00 29.81 N ATOM 1790 CA PHE B 45 3.566 -10.851 -1.051 1.00 32.54 C ATOM 1791 C PHE B 45 3.507 -12.350 -1.219 1.00 34.44 C ATOM 1792 O PHE B 45 4.299 -12.912 -1.972 1.00 28.19 O ATOM 1793 CB PHE B 45 2.965 -10.171 -2.283 1.00 27.91 C ATOM 1794 CG PHE B 45 1.557 -10.604 -2.581 1.00 33.71 C ATOM 1795 CD1 PHE B 45 0.515 -10.248 -1.733 1.00 32.29 C ATOM 1796 CD2 PHE B 45 1.276 -11.364 -3.701 1.00 32.54 C ATOM 1797 CE1 PHE B 45 -0.783 -10.648 -2.001 1.00 37.20 C ATOM 1798 CE2 PHE B 45 -0.023 -11.761 -3.983 1.00 33.08 C ATOM 1799 CZ PHE B 45 -1.054 -11.406 -3.133 1.00 34.63 C ATOM 1800 N ALA B 46 2.577 -12.988 -0.514 1.00 37.24 N ATOM 1801 CA ALA B 46 2.334 -14.415 -0.693 1.00 36.99 C ATOM 1802 C ALA B 46 3.616 -15.202 -0.480 1.00 38.17 C ATOM 1803 O ALA B 46 3.908 -16.152 -1.213 1.00 36.34 O ATOM 1804 CB ALA B 46 1.759 -14.689 -2.086 1.00 34.82 C ATOM 1805 N GLY B 47 4.399 -14.767 0.504 1.00 36.76 N ATOM 1806 CA GLY B 47 5.598 -15.476 0.897 1.00 31.97 C ATOM 1807 C GLY B 47 6.818 -15.237 0.034 1.00 34.64 C ATOM 1808 O GLY B 47 7.876 -15.774 0.327 1.00 40.73 O ATOM 1809 N LYS B 48 6.689 -14.437 -1.018 1.00 33.49 N ATOM 1810 CA LYS B 48 7.834 -14.157 -1.889 1.00 35.32 C ATOM 1811 C LYS B 48 8.261 -12.678 -1.877 1.00 33.93 C ATOM 1812 O LYS B 48 7.426 -11.771 -1.787 1.00 32.85 O ATOM 1813 CB LYS B 48 7.528 -14.583 -3.329 1.00 40.45 C ATOM 1814 CG LYS B 48 8.526 -15.586 -3.918 1.00 48.53 C ATOM 1815 CD LYS B 48 8.527 -15.555 -5.451 1.00 44.91 C ATOM 1816 CE LYS B 48 7.105 -15.482 -6.016 1.00 55.44 C ATOM 1817 NZ LYS B 48 7.078 -15.557 -7.504 1.00 55.67 N ATOM 1818 N GLN B 49 9.566 -12.447 -1.981 1.00 31.81 N ATOM 1819 CA GLN B 49 10.100 -11.098 -2.083 1.00 32.56 C ATOM 1820 C GLN B 49 9.972 -10.631 -3.526 1.00 32.91 C ATOM 1821 O GLN B 49 10.338 -11.348 -4.458 1.00 33.27 O ATOM 1822 CB GLN B 49 11.557 -11.045 -1.606 1.00 32.81 C ATOM 1823 CG GLN B 49 12.140 -9.622 -1.561 1.00 37.12 C ATOM 1824 CD GLN B 49 13.575 -9.554 -1.027 1.00 35.34 C ATOM 1825 OE1 GLN B 49 14.058 -10.467 -0.350 1.00 44.04 O ATOM 1826 NE2 GLN B 49 14.259 -8.463 -1.342 1.00 34.17 N ATOM 1827 N LEU B 50 9.450 -9.425 -3.712 1.00 26.56 N ATOM 1828 CA LEU B 50 9.057 -8.970 -5.047 1.00 29.34 C ATOM 1829 C LEU B 50 10.173 -8.216 -5.761 1.00 34.54 C ATOM 1830 O LEU B 50 10.781 -7.318 -5.178 1.00 29.98 O ATOM 1831 CB LEU B 50 7.807 -8.077 -4.951 1.00 24.10 C ATOM 1832 CG LEU B 50 6.589 -8.676 -4.238 1.00 24.28 C ATOM 1833 CD1 LEU B 50 5.409 -7.711 -4.289 1.00 21.89 C ATOM 1834 CD2 LEU B 50 6.218 -10.039 -4.826 1.00 27.05 C ATOM 1835 N GLU B 51 10.415 -8.555 -7.031 1.00 33.10 N ATOM 1836 CA GLU B 51 11.487 -7.921 -7.817 1.00 34.02 C ATOM 1837 C GLU B 51 11.010 -6.656 -8.530 1.00 31.35 C ATOM 1838 O GLU B 51 9.866 -6.591 -8.970 1.00 32.58 O ATOM 1839 CB GLU B 51 12.044 -8.894 -8.851 1.00 34.23 C ATOM 1840 CG GLU B 51 12.159 -10.323 -8.380 1.00 36.04 C ATOM 1841 CD GLU B 51 12.958 -11.159 -9.353 1.00 39.81 C ATOM 1842 OE1 GLU B 51 14.201 -11.125 -9.269 1.00 40.26 O ATOM 1843 OE2 GLU B 51 12.352 -11.841 -10.204 1.00 42.10 O ATOM 1844 N ASP B 52 11.896 -5.671 -8.659 1.00 28.20 N ATOM 1845 CA ASP B 52 11.535 -4.353 -9.184 1.00 27.85 C ATOM 1846 C ASP B 52 10.999 -4.384 -10.623 1.00 32.04 C ATOM 1847 O ASP B 52 10.115 -3.588 -10.987 1.00 27.97 O ATOM 1848 CB ASP B 52 12.737 -3.404 -9.113 1.00 26.69 C ATOM 1849 CG ASP B 52 13.111 -3.024 -7.683 1.00 27.19 C ATOM 1850 OD1 ASP B 52 12.366 -3.355 -6.738 1.00 28.49 O ATOM 1851 OD2 ASP B 52 14.152 -2.370 -7.502 1.00 30.44 O ATOM 1852 N GLY B 53 11.534 -5.300 -11.431 1.00 30.63 N ATOM 1853 CA GLY B 53 11.221 -5.350 -12.854 1.00 32.78 C ATOM 1854 C GLY B 53 9.865 -5.942 -13.218 1.00 35.32 C ATOM 1855 O GLY B 53 9.388 -5.764 -14.338 1.00 40.17 O ATOM 1856 N ARG B 54 9.239 -6.645 -12.280 1.00 32.08 N ATOM 1857 CA ARG B 54 7.968 -7.308 -12.555 1.00 31.33 C ATOM 1858 C ARG B 54 6.763 -6.440 -12.176 1.00 30.17 C ATOM 1859 O ARG B 54 6.918 -5.416 -11.516 1.00 30.60 O ATOM 1860 CB ARG B 54 7.930 -8.640 -11.817 1.00 34.94 C ATOM 1861 CG ARG B 54 9.118 -9.533 -12.153 1.00 37.11 C ATOM 1862 CD ARG B 54 8.929 -10.246 -13.497 1.00 46.08 C ATOM 1863 NE ARG B 54 7.919 -11.307 -13.421 1.00 53.88 N ATOM 1864 CZ ARG B 54 7.608 -12.133 -14.420 1.00 53.55 C ATOM 1865 NH1 ARG B 54 8.228 -12.031 -15.590 1.00 50.74 N ATOM 1866 NH2 ARG B 54 6.675 -13.066 -14.250 1.00 50.08 N ATOM 1867 N THR B 55 5.568 -6.842 -12.606 1.00 28.09 N ATOM 1868 CA THR B 55 4.360 -6.073 -12.332 1.00 31.50 C ATOM 1869 C THR B 55 3.492 -6.671 -11.234 1.00 27.34 C ATOM 1870 O THR B 55 3.679 -7.813 -10.803 1.00 26.06 O ATOM 1871 CB THR B 55 3.462 -5.938 -13.581 1.00 30.66 C ATOM 1872 OG1 THR B 55 3.058 -7.243 -14.016 1.00 29.77 O ATOM 1873 CG2 THR B 55 4.185 -5.205 -14.704 1.00 30.81 C ATOM 1874 N LEU B 56 2.506 -5.889 -10.812 1.00 30.87 N ATOM 1875 CA LEU B 56 1.553 -6.362 -9.829 1.00 27.70 C ATOM 1876 C LEU B 56 0.803 -7.572 -10.376 1.00 28.27 C ATOM 1877 O LEU B 56 0.577 -8.546 -9.651 1.00 28.14 O ATOM 1878 CB LEU B 56 0.586 -5.247 -9.436 1.00 28.73 C ATOM 1879 CG LEU B 56 1.245 -4.120 -8.644 1.00 27.54 C ATOM 1880 CD1 LEU B 56 0.188 -3.198 -8.076 1.00 25.03 C ATOM 1881 CD2 LEU B 56 2.134 -4.683 -7.539 1.00 19.16 C ATOM 1882 N SER B 57 0.435 -7.526 -11.656 1.00 31.34 N ATOM 1883 CA SER B 57 -0.324 -8.628 -12.233 1.00 31.47 C ATOM 1884 C SER B 57 0.570 -9.855 -12.353 1.00 26.37 C ATOM 1885 O SER B 57 0.103 -10.972 -12.157 1.00 28.94 O ATOM 1886 CB SER B 57 -0.923 -8.252 -13.595 1.00 35.54 C ATOM 1887 OG SER B 57 0.090 -7.917 -14.520 1.00 45.84 O ATOM 1888 N ASP B 58 1.855 -9.646 -12.638 1.00 33.64 N ATOM 1889 CA ASP B 58 2.810 -10.751 -12.691 1.00 28.78 C ATOM 1890 C ASP B 58 2.684 -11.611 -11.437 1.00 32.17 C ATOM 1891 O ASP B 58 2.733 -12.827 -11.514 1.00 30.46 O ATOM 1892 CB ASP B 58 4.253 -10.243 -12.839 1.00 34.98 C ATOM 1893 CG ASP B 58 4.593 -9.829 -14.265 1.00 37.63 C ATOM 1894 OD1 ASP B 58 3.959 -10.345 -15.208 1.00 44.43 O ATOM 1895 OD2 ASP B 58 5.489 -8.980 -14.449 1.00 36.55 O ATOM 1896 N TYR B 59 2.477 -10.971 -10.288 1.00 30.11 N ATOM 1897 CA TYR B 59 2.382 -11.682 -9.014 1.00 30.11 C ATOM 1898 C TYR B 59 0.955 -11.964 -8.549 1.00 30.04 C ATOM 1899 O TYR B 59 0.745 -12.342 -7.396 1.00 26.13 O ATOM 1900 CB TYR B 59 3.092 -10.885 -7.918 1.00 34.44 C ATOM 1901 CG TYR B 59 4.587 -10.773 -8.082 1.00 26.39 C ATOM 1902 CD1 TYR B 59 5.413 -11.843 -7.784 1.00 27.47 C ATOM 1903 CD2 TYR B 59 5.172 -9.592 -8.505 1.00 26.91 C ATOM 1904 CE1 TYR B 59 6.800 -11.745 -7.925 1.00 29.46 C ATOM 1905 CE2 TYR B 59 6.554 -9.485 -8.643 1.00 32.95 C ATOM 1906 CZ TYR B 59 7.361 -10.563 -8.353 1.00 24.96 C ATOM 1907 OH TYR B 59 8.728 -10.455 -8.490 1.00 28.44 O ATOM 1908 N ASN B 60 -0.022 -11.770 -9.430 1.00 29.79 N ATOM 1909 CA ASN B 60 -1.431 -11.922 -9.057 1.00 30.00 C ATOM 1910 C ASN B 60 -1.767 -11.059 -7.838 1.00 32.18 C ATOM 1911 O ASN B 60 -2.417 -11.510 -6.890 1.00 30.40 O ATOM 1912 CB ASN B 60 -1.772 -13.397 -8.788 1.00 35.57 C ATOM 1913 CG ASN B 60 -3.267 -13.671 -8.851 1.00 42.09 C ATOM 1914 OD1 ASN B 60 -4.049 -12.810 -9.258 1.00 44.95 O ATOM 1915 ND2 ASN B 60 -3.671 -14.875 -8.455 1.00 43.82 N ATOM 1916 N ILE B 61 -1.286 -9.820 -7.864 1.00 29.32 N ATOM 1917 CA ILE B 61 -1.639 -8.845 -6.844 1.00 33.75 C ATOM 1918 C ILE B 61 -2.814 -8.053 -7.387 1.00 29.30 C ATOM 1919 O ILE B 61 -2.718 -7.402 -8.431 1.00 29.25 O ATOM 1920 CB ILE B 61 -0.440 -7.922 -6.478 1.00 29.72 C ATOM 1921 CG1 ILE B 61 0.616 -8.730 -5.716 1.00 31.69 C ATOM 1922 CG2 ILE B 61 -0.900 -6.744 -5.641 1.00 25.37 C ATOM 1923 CD1 ILE B 61 1.996 -8.150 -5.767 1.00 30.17 C ATOM 1924 N GLN B 62 -3.943 -8.135 -6.702 1.00 30.42 N ATOM 1925 CA GLN B 62 -5.180 -7.606 -7.273 1.00 31.81 C ATOM 1926 C GLN B 62 -5.811 -6.564 -6.352 1.00 31.95 C ATOM 1927 O GLN B 62 -5.193 -6.159 -5.365 1.00 30.84 O ATOM 1928 CB GLN B 62 -6.141 -8.759 -7.577 1.00 34.52 C ATOM 1929 CG GLN B 62 -5.891 -10.029 -6.777 1.00 39.18 C ATOM 1930 CD GLN B 62 -6.816 -11.193 -7.175 1.00 44.13 C ATOM 1931 OE1 GLN B 62 -8.028 -11.118 -7.002 1.00 45.09 O ATOM 1932 NE2 GLN B 62 -6.236 -12.276 -7.690 1.00 47.70 N ATOM 1933 N LYS B 63 -7.012 -6.102 -6.682 1.00 31.15 N ATOM 1934 CA LYS B 63 -7.645 -5.048 -5.885 1.00 32.15 C ATOM 1935 C LYS B 63 -7.733 -5.492 -4.414 1.00 34.85 C ATOM 1936 O LYS B 63 -8.039 -6.649 -4.115 1.00 30.02 O ATOM 1937 CB LYS B 63 -9.013 -4.680 -6.477 1.00 34.63 C ATOM 1938 CG LYS B 63 -10.250 -5.096 -5.693 1.00 43.07 C ATOM 1939 CD LYS B 63 -11.529 -4.601 -6.413 1.00 45.68 C ATOM 1940 CE LYS B 63 -12.816 -5.061 -5.719 1.00 45.97 C ATOM 1941 NZ LYS B 63 -12.989 -6.548 -5.737 1.00 44.51 N ATOM 1942 N GLU B 64 -7.358 -4.583 -3.512 1.00 33.07 N ATOM 1943 CA GLU B 64 -7.309 -4.833 -2.062 1.00 29.17 C ATOM 1944 C GLU B 64 -6.393 -5.952 -1.549 1.00 29.36 C ATOM 1945 O GLU B 64 -6.510 -6.346 -0.385 1.00 30.10 O ATOM 1946 CB GLU B 64 -8.714 -5.112 -1.541 1.00 36.06 C ATOM 1947 CG GLU B 64 -9.608 -3.902 -1.522 1.00 38.90 C ATOM 1948 CD GLU B 64 -11.057 -4.291 -1.452 1.00 48.66 C ATOM 1949 OE1 GLU B 64 -11.373 -5.342 -0.836 1.00 46.38 O ATOM 1950 OE2 GLU B 64 -11.872 -3.555 -2.042 1.00 46.80 O ATOM 1951 N SER B 65 -5.485 -6.459 -2.376 1.00 23.43 N ATOM 1952 CA SER B 65 -4.466 -7.390 -1.897 1.00 26.83 C ATOM 1953 C SER B 65 -3.575 -6.677 -0.890 1.00 27.27 C ATOM 1954 O SER B 65 -3.474 -5.450 -0.915 1.00 28.13 O ATOM 1955 CB SER B 65 -3.605 -7.925 -3.048 1.00 29.93 C ATOM 1956 OG SER B 65 -4.372 -8.667 -3.977 1.00 31.46 O ATOM 1957 N THR B 66 -2.918 -7.438 -0.019 1.00 27.10 N ATOM 1958 CA THR B 66 -2.026 -6.843 0.981 1.00 30.27 C ATOM 1959 C THR B 66 -0.566 -7.241 0.794 1.00 30.26 C ATOM 1960 O THR B 66 -0.216 -8.419 0.858 1.00 29.19 O ATOM 1961 CB THR B 66 -2.453 -7.226 2.412 1.00 27.99 C ATOM 1962 OG1 THR B 66 -3.738 -6.657 2.687 1.00 28.16 O ATOM 1963 CG2 THR B 66 -1.451 -6.702 3.427 1.00 29.74 C ATOM 1964 N LEU B 67 0.280 -6.246 0.563 1.00 29.14 N ATOM 1965 CA LEU B 67 1.718 -6.458 0.557 1.00 29.04 C ATOM 1966 C LEU B 67 2.289 -6.256 1.966 1.00 29.31 C ATOM 1967 O LEU B 67 1.646 -5.661 2.830 1.00 29.48 O ATOM 1968 CB LEU B 67 2.407 -5.498 -0.409 1.00 25.32 C ATOM 1969 CG LEU B 67 1.920 -5.238 -1.829 1.00 32.17 C ATOM 1970 CD1 LEU B 67 3.112 -4.751 -2.667 1.00 26.87 C ATOM 1971 CD2 LEU B 67 1.256 -6.462 -2.453 1.00 29.08 C ATOM 1972 N HIS B 68 3.505 -6.739 2.184 1.00 28.01 N ATOM 1973 CA HIS B 68 4.205 -6.514 3.438 1.00 24.26 C ATOM 1974 C HIS B 68 5.515 -5.758 3.206 1.00 27.81 C ATOM 1975 O HIS B 68 6.282 -6.092 2.293 1.00 24.05 O ATOM 1976 CB HIS B 68 4.470 -7.852 4.138 1.00 32.47 C ATOM 1977 CG HIS B 68 3.226 -8.581 4.532 1.00 32.45 C ATOM 1978 ND1 HIS B 68 2.524 -8.289 5.688 1.00 27.98 N ATOM 1979 CD2 HIS B 68 2.541 -9.579 3.922 1.00 30.52 C ATOM 1980 CE1 HIS B 68 1.474 -9.082 5.772 1.00 31.16 C ATOM 1981 NE2 HIS B 68 1.460 -9.872 4.713 1.00 34.06 N ATOM 1982 N LEU B 69 5.762 -4.739 4.032 1.00 22.28 N ATOM 1983 CA LEU B 69 6.978 -3.941 3.928 1.00 19.07 C ATOM 1984 C LEU B 69 7.953 -4.226 5.074 1.00 22.21 C ATOM 1985 O LEU B 69 7.626 -4.065 6.252 1.00 20.73 O ATOM 1986 CB LEU B 69 6.653 -2.443 3.901 1.00 18.59 C ATOM 1987 CG LEU B 69 7.865 -1.484 3.891 1.00 17.06 C ATOM 1988 CD1 LEU B 69 8.544 -1.415 2.516 1.00 22.74 C ATOM 1989 CD2 LEU B 69 7.510 -0.082 4.385 1.00 20.64 C ATOM 1990 N VAL B 70 9.163 -4.635 4.712 1.00 19.73 N ATOM 1991 CA VAL B 70 10.236 -4.761 5.672 1.00 17.27 C ATOM 1992 C VAL B 70 11.374 -3.900 5.161 1.00 21.12 C ATOM 1993 O VAL B 70 11.669 -3.879 3.957 1.00 20.58 O ATOM 1994 CB VAL B 70 10.678 -6.236 5.874 1.00 18.76 C ATOM 1995 CG1 VAL B 70 11.195 -6.848 4.581 1.00 20.27 C ATOM 1996 CG2 VAL B 70 11.708 -6.333 6.982 1.00 19.08 C ATOM 1997 N LEU B 71 11.980 -3.144 6.067 1.00 18.44 N ATOM 1998 CA LEU B 71 13.003 -2.181 5.683 1.00 20.64 C ATOM 1999 C LEU B 71 14.380 -2.816 5.776 1.00 20.56 C ATOM 2000 O LEU B 71 14.603 -3.677 6.629 1.00 18.88 O ATOM 2001 CB LEU B 71 12.924 -0.944 6.575 1.00 19.49 C ATOM 2002 CG LEU B 71 11.717 -0.024 6.335 1.00 18.44 C ATOM 2003 CD1 LEU B 71 11.567 0.978 7.462 1.00 19.10 C ATOM 2004 CD2 LEU B 71 11.881 0.711 5.014 1.00 22.81 C ATOM 2005 N ARG B 72 15.314 -2.402 4.920 1.00 20.58 N ATOM 2006 CA ARG B 72 16.697 -2.773 5.183 1.00 23.74 C ATOM 2007 C ARG B 72 17.163 -1.972 6.387 1.00 22.54 C ATOM 2008 O ARG B 72 16.499 -1.030 6.829 1.00 23.60 O ATOM 2009 CB ARG B 72 17.620 -2.533 3.978 1.00 22.33 C ATOM 2010 CG ARG B 72 18.127 -1.127 3.857 1.00 30.30 C ATOM 2011 CD ARG B 72 19.106 -0.909 2.691 1.00 31.84 C ATOM 2012 NE ARG B 72 19.441 0.519 2.637 1.00 39.88 N ATOM 2013 CZ ARG B 72 20.055 1.139 1.635 1.00 38.11 C ATOM 2014 NH1 ARG B 72 20.436 0.470 0.559 1.00 36.23 N ATOM 2015 NH2 ARG B 72 20.289 2.442 1.725 1.00 41.84 N ATOM 2016 N LEU B 73 18.306 -2.372 6.916 1.00 19.00 N ATOM 2017 CA LEU B 73 18.964 -1.683 8.019 1.00 25.39 C ATOM 2018 C LEU B 73 20.406 -1.390 7.600 1.00 25.89 C ATOM 2019 O LEU B 73 21.105 -2.290 7.141 1.00 25.81 O ATOM 2020 CB LEU B 73 18.924 -2.554 9.282 1.00 22.10 C ATOM 2021 CG LEU B 73 19.075 -1.927 10.663 1.00 21.83 C ATOM 2022 CD1 LEU B 73 17.875 -1.044 10.998 1.00 23.90 C ATOM 2023 CD2 LEU B 73 19.227 -3.029 11.688 1.00 19.37 C ATOM 2024 N ARG B 74 20.835 -0.141 7.741 1.00 23.26 N ATOM 2025 CA ARG B 74 22.204 0.260 7.425 1.00 23.73 C ATOM 2026 C ARG B 74 22.745 1.146 8.509 1.00 22.81 C ATOM 2027 O ARG B 74 22.226 2.236 8.726 1.00 17.48 O ATOM 2028 CB ARG B 74 22.271 1.025 6.114 1.00 25.07 C ATOM 2029 CG ARG B 74 22.498 0.208 4.880 1.00 36.26 C ATOM 2030 CD ARG B 74 22.601 1.202 3.752 1.00 44.50 C ATOM 2031 NE ARG B 74 23.182 0.656 2.535 1.00 57.94 N ATOM 2032 CZ ARG B 74 23.643 1.413 1.542 1.00 59.68 C ATOM 2033 NH1 ARG B 74 23.585 2.740 1.640 1.00 57.13 N ATOM 2034 NH2 ARG B 74 24.165 0.850 0.458 1.00 65.26 N ATOM 2035 N GLY B 75 23.799 0.698 9.183 1.00 21.79 N ATOM 2036 CA GLY B 75 24.415 1.513 10.202 1.00 23.35 C ATOM 2037 C GLY B 75 25.786 1.975 9.752 1.00 30.85 C ATOM 2038 O GLY B 75 26.311 1.495 8.747 1.00 27.92 O ATOM 2039 N GLY B 76 26.358 2.898 10.516 1.00 25.32 N ATOM 2040 CA GLY B 76 27.658 3.451 10.215 1.00 29.91 C ATOM 2041 C GLY B 76 28.160 4.208 11.420 1.00 28.53 C ATOM 2042 O GLY B 76 29.306 4.043 11.817 1.00 37.23 O ATOM 2043 OXT GLY B 76 27.443 4.989 12.053 1.00 32.20 O TER 2044 GLY B 76 HETATM 2045 ZN ZN A 501 21.382 12.670 3.517 1.00 29.93 ZN HETATM 2046 C1 EDO A 502 2.774 -11.763 30.627 1.00 35.81 C HETATM 2047 O1 EDO A 502 3.001 -13.117 31.017 1.00 38.20 O HETATM 2048 C2 EDO A 502 4.055 -10.998 30.899 1.00 39.85 C HETATM 2049 O2 EDO A 502 3.875 -9.655 30.446 1.00 53.61 O HETATM 2050 C1 EDO A 503 12.582 12.795 33.124 1.00 37.33 C HETATM 2051 O1 EDO A 503 12.621 11.688 32.210 1.00 45.75 O HETATM 2052 C2 EDO A 503 14.003 13.255 33.445 1.00 38.38 C HETATM 2053 O2 EDO A 503 14.915 12.931 32.390 1.00 35.37 O HETATM 2054 C1 EDO B 101 8.826 -1.774 9.138 1.00 23.12 C HETATM 2055 O1 EDO B 101 7.994 -2.548 8.256 1.00 18.09 O HETATM 2056 C2 EDO B 101 10.326 -2.019 8.933 1.00 19.07 C HETATM 2057 O2 EDO B 101 10.761 -3.391 9.010 1.00 20.60 O HETATM 2058 O HOH A 601 21.228 2.202 15.924 1.00 16.58 O HETATM 2059 O HOH A 602 25.656 6.171 13.977 1.00 25.10 O HETATM 2060 O HOH A 603 11.430 8.484 18.339 1.00 12.89 O HETATM 2061 O HOH A 604 18.681 9.314 26.338 1.00 29.30 O HETATM 2062 O HOH A 605 6.635 9.898 12.522 1.00 23.34 O HETATM 2063 O HOH A 606 13.512 20.573 8.085 1.00 30.08 O HETATM 2064 O HOH A 607 28.349 -7.321 11.481 1.00 28.33 O HETATM 2065 O HOH A 608 16.140 12.626 29.593 1.00 37.64 O HETATM 2066 O HOH A 609 13.084 7.847 4.998 1.00 21.22 O HETATM 2067 O HOH A 610 15.831 8.088 4.453 1.00 22.19 O HETATM 2068 O HOH A 611 20.051 -1.654 27.542 1.00 30.86 O HETATM 2069 O HOH A 612 12.097 -4.966 10.990 1.00 17.32 O HETATM 2070 O HOH A 613 -0.983 5.754 27.585 1.00 37.64 O HETATM 2071 O HOH A 614 9.011 11.039 16.266 1.00 19.59 O HETATM 2072 O HOH A 615 21.136 1.919 32.713 1.00 46.71 O HETATM 2073 O HOH A 616 11.332 -7.461 28.199 1.00 28.08 O HETATM 2074 O HOH A 617 15.614 10.103 2.202 1.00 32.86 O HETATM 2075 O HOH A 618 18.049 20.148 9.330 1.00 33.64 O HETATM 2076 O HOH A 619 37.524 5.930 14.335 1.00 40.22 O HETATM 2077 O HOH A 620 23.512 18.182 10.781 1.00 33.20 O HETATM 2078 O HOH A 621 24.174 8.271 3.937 1.00 37.85 O HETATM 2079 O HOH A 622 0.614 1.289 16.885 1.00 38.10 O HETATM 2080 O HOH A 623 34.409 9.559 15.593 1.00 36.84 O HETATM 2081 O HOH A 624 19.621 16.293 -1.618 1.00 34.41 O HETATM 2082 O HOH A 625 5.792 8.915 27.127 1.00 36.98 O HETATM 2083 O HOH A 626 1.841 -5.747 19.912 1.00 36.00 O HETATM 2084 O HOH A 627 26.439 20.182 8.945 1.00 36.55 O HETATM 2085 O HOH A 628 10.842 13.685 23.408 1.00 31.09 O HETATM 2086 O HOH A 629 -0.093 -4.422 18.481 1.00 29.68 O HETATM 2087 O HOH A 630 31.390 -9.165 7.100 1.00 43.22 O HETATM 2088 O HOH A 631 8.978 -13.955 3.589 1.00 36.60 O HETATM 2089 O HOH A 632 24.972 20.494 3.693 1.00 43.87 O HETATM 2090 O HOH A 633 21.572 16.898 14.107 1.00 22.68 O HETATM 2091 O HOH A 634 25.395 -12.624 8.935 1.00 27.04 O HETATM 2092 O HOH A 635 29.560 -8.859 9.308 1.00 37.35 O HETATM 2093 O HOH A 636 15.605 -14.739 1.743 1.00 34.19 O HETATM 2094 O HOH A 637 2.526 4.938 26.415 1.00 34.13 O HETATM 2095 O HOH A 638 26.044 16.399 9.178 1.00 34.02 O HETATM 2096 O HOH A 639 20.603 0.261 29.175 1.00 42.75 O HETATM 2097 O HOH A 640 1.950 -15.109 11.815 1.00 34.84 O HETATM 2098 O HOH A 641 5.869 -16.233 9.221 1.00 34.10 O HETATM 2099 O HOH A 642 19.002 1.453 5.385 1.00 26.41 O HETATM 2100 O HOH A 643 5.771 15.720 15.742 1.00 33.31 O HETATM 2101 O HOH A 644 27.972 -9.842 12.075 1.00 34.73 O HETATM 2102 O HOH B 201 15.923 4.554 -3.377 1.00 27.50 O HETATM 2103 O HOH B 202 19.726 3.745 4.590 1.00 32.53 O HETATM 2104 O HOH B 203 3.856 -13.246 2.909 1.00 31.98 O HETATM 2105 O HOH B 204 8.402 12.096 0.199 1.00 32.54 O HETATM 2106 O HOH B 205 2.301 -4.590 11.750 1.00 31.46 O HETATM 2107 O HOH B 206 9.148 11.161 -3.442 1.00 35.20 O HETATM 2108 O HOH B 207 13.721 -4.184 9.280 1.00 18.28 O HETATM 2109 O HOH B 208 14.863 -1.899 -3.152 1.00 21.54 O HETATM 2110 O HOH B 209 5.653 8.348 6.261 1.00 27.61 O HETATM 2111 O HOH B 210 11.174 -5.837 -2.893 1.00 22.91 O HETATM 2112 O HOH B 211 16.459 1.746 6.260 1.00 25.89 O HETATM 2113 O HOH B 212 0.358 -10.365 -16.365 1.00 35.36 O HETATM 2114 O HOH B 213 14.051 -5.986 -2.989 1.00 30.39 O HETATM 2115 O HOH B 214 -8.249 0.217 -11.217 1.00 36.51 O HETATM 2116 O HOH B 215 -0.819 6.302 -4.296 1.00 30.62 O HETATM 2117 O HOH B 216 2.146 -0.534 16.907 1.00 28.77 O HETATM 2118 O HOH B 217 -0.528 -10.697 1.725 1.00 37.07 O HETATM 2119 O HOH B 218 12.676 9.851 0.907 1.00 29.46 O HETATM 2120 O HOH B 219 31.262 5.926 11.239 1.00 35.37 O HETATM 2121 O HOH B 220 -3.868 4.094 5.120 1.00 35.90 O HETATM 2122 O HOH B 221 13.513 -6.811 -11.037 1.00 38.18 O HETATM 2123 O HOH B 222 10.404 -3.398 -15.932 1.00 34.68 O HETATM 2124 O HOH B 223 1.462 11.665 2.208 1.00 33.36 O HETATM 2125 O HOH B 224 -3.740 -12.886 -4.814 1.00 34.26 O HETATM 2126 O HOH B 225 15.689 -9.816 1.527 1.00 34.50 O HETATM 2127 O HOH B 226 -8.202 -7.009 -8.951 1.00 34.85 O HETATM 2128 O HOH B 227 19.521 -5.708 1.671 1.00 27.75 O HETATM 2129 O HOH B 228 -9.358 2.532 -6.860 1.00 39.96 O HETATM 2130 O HOH B 229 11.522 2.934 -7.392 1.00 23.74 O HETATM 2131 O HOH B 230 14.778 -1.303 -5.464 1.00 32.37 O HETATM 2132 O HOH B 231 -4.980 -10.839 -2.866 1.00 33.31 O HETATM 2133 O HOH B 232 -3.912 -9.943 0.089 1.00 29.57 O HETATM 2134 O HOH B 233 1.734 8.066 7.243 1.00 36.99 O HETATM 2135 O HOH B 234 -14.076 -8.428 -5.052 1.00 38.93 O CONECT 840 2045 CONECT 1151 2045 CONECT 1211 2045 CONECT 1228 2045 CONECT 2045 840 1151 1211 1228 CONECT 2046 2047 2048 CONECT 2047 2046 CONECT 2048 2046 2049 CONECT 2049 2048 CONECT 2050 2051 2052 CONECT 2051 2050 CONECT 2052 2050 2053 CONECT 2053 2052 CONECT 2054 2055 2056 CONECT 2055 2054 CONECT 2056 2054 2057 CONECT 2057 2056 MASTER 325 0 4 6 25 0 4 6 2133 2 17 23 END
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Related entries of code: 4pqt
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
4k1r
RCSB PDB
PDBbind
197aa, >4K1R_1|Chains... *
4msm
RCSB PDB
PDBbind
197aa, >4MSM_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
4pqt
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
Schizosaccharomyces pombe sst2 catalytic domain (D354A mutant)
Ligand Name
Ubiquitin Protein UBBP4
EC.Number
E.C.3.4.19
Resolution
2.05(Å)
Affinity (Kd/Ki/IC50)
Kd=1.1uM
Release Year
2014
Protein/NA Sequence
Check fasta file
Primary Reference
(2014) Biochemistry Vol. 53: pp. 3199-3217
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q9P371
Entrez Gene ID
No matched NCBI Entrez Gene ID found!
ASD
Information of known allosteric effects of PDB entries
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