Browse entries in the PDBbind-CN Database

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Related entries of code: 4x8s
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1w0yRCSB PDB    PDBbind142aa, >1W0Y_2|Chain... at 100%
1w2kRCSB PDB    PDBbind142aa, >1W2K_2|Chain... at 100%
1w7xRCSB PDB    PDBbind55aa, >1W7X_2|Chain... at 100%
1wqvRCSB PDB    PDBbind152aa, >1WQV_1|Chain... at 100%
1wssRCSB PDB    PDBbind152aa, >1WSS_1|Chain... at 100%
1wtgRCSB PDB    PDBbind152aa, >1WTG_1|Chain... at 100%
1wunRCSB PDB    PDBbind152aa, >1WUN_1|Chain... at 100%
1wv7RCSB PDB    PDBbind152aa, >1WV7_1|Chain... at 100%
1z6jRCSB PDB    PDBbind142aa, >1Z6J_1|Chain... at 100%
2aeiRCSB PDB    PDBbind152aa, >2AEI_1|Chain... at 100%
2b7dRCSB PDB    PDBbind152aa, >2B7D_1|Chain... at 100%
2bz6RCSB PDB    PDBbind53aa, >2BZ6_2|Chain... at 100%
2c4fRCSB PDB    PDBbind142aa, >2C4F_2|Chain... at 100%
2f9bRCSB PDB    PDBbind152aa, >2F9B_1|Chain... at 100%
2flbRCSB PDB    PDBbind152aa, >2FLB_1|Chain... at 100%
2flrRCSB PDB    PDBbind152aa, >2FLR_1|Chain... at 100%
2zp0RCSB PDB    PDBbind152aa, >2ZP0_1|Chain... at 100%
2zzuRCSB PDB    PDBbind152aa, >2ZZU_1|Chain... at 100%
4ishRCSB PDB    PDBbind55aa, >4ISH_2|Chain... at 100%
4isiRCSB PDB    PDBbind55aa, >4ISI_2|Chain... at 100%
4jyuRCSB PDB    PDBbind55aa, >4JYU_2|Chain... at 100%
4jyvRCSB PDB    PDBbind55aa, >4JYV_2|Chain... at 100%
4jzdRCSB PDB    PDBbind55aa, >4JZD_2|Chain... at 100%
4jzeRCSB PDB    PDBbind55aa, >4JZE_2|Chain... at 100%
4jzfRCSB PDB    PDBbind55aa, >4JZF_2|Chain... at 100%
4na9RCSB PDB    PDBbind55aa, >4NA9_2|Chain... at 100%
4ng9RCSB PDB    PDBbind55aa, >4NG9_2|Chain... at 100%
4ngaRCSB PDB    PDBbind55aa, >4NGA_2|Chain... at 100%
4x8tRCSB PDB    PDBbind55aa, >4X8T_2|Chain... at 100%
4x8uRCSB PDB    PDBbind55aa, >4X8U_2|Chain... at 100%
4x8vRCSB PDB    PDBbind55aa, >4X8V_2|Chain... at 100%
4yt6RCSB PDB    PDBbind57aa, >4YT6_2|Chain... at 100%
4yt7RCSB PDB    PDBbind57aa, >4YT7_2|Chain... at 100%
4zxxRCSB PDB    PDBbind55aa, >4ZXX_2|Chain... at 100%
4zxyRCSB PDB    PDBbind55aa, >4ZXY_2|Chain... at 100%
5l2yRCSB PDB    PDBbind55aa, >5L2Y_2|Chain... at 100%
5l2zRCSB PDB    PDBbind58aa, >5L2Z_2|Chain... at 100%
5l30RCSB PDB    PDBbind58aa, >5L30_2|Chain... at 100%
5tqeRCSB PDB    PDBbind55aa, >5TQE_2|Chain... at 100%
5tqfRCSB PDB    PDBbind55aa, >5TQF_2|Chain... at 100%
5tqgRCSB PDB    PDBbind55aa, >5TQG_2|Chain... at 100%
5u6jRCSB PDB    PDBbind55aa, >5U6J_2|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID4x8s
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameFactor VIIa
Ligand Name3Z7
EC.Number E.C.3.4.21.21
Resolution 2.1(Å)
Affinity (Kd/Ki/IC50)Ki=13mM
Release Year2015
Protein/NA SequenceCheck fasta file
Primary Reference (2015) J.Med.Chem. Vol. 58: pp. 2799-2808
Ligand Properties
Formula C7H7BrO2
Molecular Weight 203.033
Exact Mass 201.963
No. of atoms 17
No. of bonds 17
Polar Surface Area 29.46
LOGP Value 2.23      (Computed with XLOGP3)
2.16      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 1
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 2
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P08709  
Entrez Gene IDNCBI Entrez Gene ID: 2155  
ASDInformation of known allosteric effects of PDB entries
 
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