Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 12-FEB-15 4Y60 TITLE STRUCTURE OF SOX18-HMG/PROX1-DNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTION FACTOR SOX-18; COMPND 3 CHAIN: C; COMPND 4 FRAGMENT: UNP RESIDUES 77-155; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: DNA (5'- COMPND 8 D(*CP*AP*CP*TP*AP*GP*CP*AP*TP*TP*GP*TP*CP*TP*GP*GP*G)-3'); COMPND 9 CHAIN: A; COMPND 10 ENGINEERED: YES; COMPND 11 MOL_ID: 3; COMPND 12 MOLECULE: DNA (5'- COMPND 13 D(*GP*CP*CP*CP*AP*GP*AP*CP*AP*AP*TP*GP*CP*TP*AP*GP*T)-3'); COMPND 14 CHAIN: B; COMPND 15 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 3 ORGANISM_COMMON: MOUSE; SOURCE 4 ORGANISM_TAXID: 10090; SOURCE 5 GENE: SOX18, SOX-18; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 11 ORGANISM_TAXID: 10090; SOURCE 12 MOL_ID: 3; SOURCE 13 SYNTHETIC: YES; SOURCE 14 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 15 ORGANISM_TAXID: 10090 KEYWDS TRANSCRIPTION FACTOR, SOX, PROTEIN-DNA, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR K.NARASIMHAN,N.PROKOPH,P.KOLATKAR,H.ROBINSON,R.JAUCH REVDAT 2 06-APR-16 4Y60 1 JRNL REVDAT 1 02-MAR-16 4Y60 0 JRNL AUTH M.KLAUS,N.PROKOPH,M.GIRBIG,X.WANG,Y.H.HUANG,Y.SRIVASTAVA, JRNL AUTH 2 L.HOU,K.NARASIMHAN,P.R.KOLATKAR,M.FRANCOIS,R.JAUCH JRNL TITL STRUCTURE AND DECOY-MEDIATED INHIBITION OF THE JRNL TITL 2 SOX18/PROX1-DNA INTERACTION. JRNL REF NUCLEIC ACIDS RES. 2016 JRNL REFN ESSN 1362-4962 JRNL PMID 26939885 JRNL DOI 10.1093/NAR/GKW130 REMARK 2 REMARK 2 RESOLUTION. 1.75 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (PHENIX.REFINE: 1.8_1069) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.75 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 36.64 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 3 NUMBER OF REFLECTIONS : 23869 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.175 REMARK 3 R VALUE (WORKING SET) : 0.174 REMARK 3 FREE R VALUE : 0.199 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.120 REMARK 3 FREE R VALUE TEST SET COUNT : 1222 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 36.6496 - 3.6380 1.00 2597 155 0.1550 0.1843 REMARK 3 2 3.6380 - 2.8880 1.00 2550 137 0.1560 0.1751 REMARK 3 3 2.8880 - 2.5230 1.00 2509 136 0.1978 0.2134 REMARK 3 4 2.5230 - 2.2924 1.00 2506 134 0.1886 0.2318 REMARK 3 5 2.2924 - 2.1281 1.00 2530 117 0.1911 0.2119 REMARK 3 6 2.1281 - 2.0026 1.00 2468 155 0.2032 0.2303 REMARK 3 7 2.0026 - 1.9023 1.00 2481 124 0.2070 0.2225 REMARK 3 8 1.9023 - 1.8195 1.00 2490 145 0.2106 0.2381 REMARK 3 9 1.8195 - 1.7495 1.00 2516 119 0.2263 0.2681 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.180 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 21.210 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.010 1419 REMARK 3 ANGLE : 1.904 2053 REMARK 3 CHIRALITY : 0.163 219 REMARK 3 PLANARITY : 0.007 150 REMARK 3 DIHEDRAL : 25.873 593 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 16 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: (CHAIN C AND RESID 0:7) REMARK 3 ORIGIN FOR THE GROUP (A): 43.7358 -53.5221 -8.5248 REMARK 3 T TENSOR REMARK 3 T11: 0.4115 T22: 0.3670 REMARK 3 T33: 0.3283 T12: -0.0241 REMARK 3 T13: 0.0020 T23: -0.1016 REMARK 3 L TENSOR REMARK 3 L11: 4.6007 L22: 4.4914 REMARK 3 L33: 2.3345 L12: 0.0689 REMARK 3 L13: -0.6156 L23: 2.8899 REMARK 3 S TENSOR REMARK 3 S11: -0.2635 S12: 0.4416 S13: -0.4959 REMARK 3 S21: -0.9103 S22: 0.3855 S23: 0.0618 REMARK 3 S31: 0.6430 S32: 0.7896 S33: -0.2376 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: (CHAIN C AND RESID 8:15) REMARK 3 ORIGIN FOR THE GROUP (A): 46.9666 -42.1701 0.7304 REMARK 3 T TENSOR REMARK 3 T11: 0.1882 T22: 0.2425 REMARK 3 T33: 0.2280 T12: -0.0052 REMARK 3 T13: -0.0196 T23: -0.0268 REMARK 3 L TENSOR REMARK 3 L11: 9.1318 L22: 2.5151 REMARK 3 L33: 3.1869 L12: 4.4591 REMARK 3 L13: 0.6810 L23: -0.7067 REMARK 3 S TENSOR REMARK 3 S11: 0.3050 S12: -0.4019 S13: -0.4001 REMARK 3 S21: 0.0141 S22: -0.3935 S23: -0.3529 REMARK 3 S31: 0.3090 S32: -0.1205 S33: 0.1021 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: (CHAIN C AND RESID 16:23) REMARK 3 ORIGIN FOR THE GROUP (A): 56.8974 -36.9179 -1.0854 REMARK 3 T TENSOR REMARK 3 T11: 0.3393 T22: 0.2721 REMARK 3 T33: 0.3664 T12: 0.0427 REMARK 3 T13: 0.0561 T23: 0.0258 REMARK 3 L TENSOR REMARK 3 L11: 2.2142 L22: 7.4392 REMARK 3 L33: 8.4388 L12: 1.6885 REMARK 3 L13: 1.3514 L23: -1.6058 REMARK 3 S TENSOR REMARK 3 S11: 0.5097 S12: 0.2949 S13: 0.7611 REMARK 3 S21: -0.2843 S22: -0.5559 S23: 0.0127 REMARK 3 S31: -0.8095 S32: 0.0751 S33: -0.0699 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: (CHAIN C AND RESID 24:33) REMARK 3 ORIGIN FOR THE GROUP (A): 63.4311 -41.6563 2.8042 REMARK 3 T TENSOR REMARK 3 T11: 0.2469 T22: 0.3476 REMARK 3 T33: 0.3327 T12: 0.0247 REMARK 3 T13: 0.0106 T23: 0.0049 REMARK 3 L TENSOR REMARK 3 L11: 7.0257 L22: 6.5008 REMARK 3 L33: 7.0542 L12: 6.7111 REMARK 3 L13: -1.9235 L23: -2.3562 REMARK 3 S TENSOR REMARK 3 S11: 0.0960 S12: 0.0517 S13: -0.3484 REMARK 3 S21: -0.1695 S22: -0.1599 S23: -0.4680 REMARK 3 S31: -0.0344 S32: 0.5978 S33: 0.0857 REMARK 3 TLS GROUP : 5 REMARK 3 SELECTION: (CHAIN C AND RESID 34:42) REMARK 3 ORIGIN FOR THE GROUP (A): 52.3525 -41.1721 9.0612 REMARK 3 T TENSOR REMARK 3 T11: 0.2798 T22: 0.2619 REMARK 3 T33: 0.2034 T12: -0.0236 REMARK 3 T13: 0.0130 T23: -0.0045 REMARK 3 L TENSOR REMARK 3 L11: 9.6784 L22: 7.0216 REMARK 3 L33: 3.5740 L12: -5.1897 REMARK 3 L13: 0.7452 L23: 1.0350 REMARK 3 S TENSOR REMARK 3 S11: -0.3370 S12: -0.7734 S13: -0.2842 REMARK 3 S21: 0.7507 S22: 0.1616 S23: 0.0979 REMARK 3 S31: 0.1796 S32: -0.0981 S33: 0.1244 REMARK 3 TLS GROUP : 6 REMARK 3 SELECTION: (CHAIN C AND RESID 43:48) REMARK 3 ORIGIN FOR THE GROUP (A): 43.8997 -32.7515 9.6205 REMARK 3 T TENSOR REMARK 3 T11: 0.2995 T22: 0.3750 REMARK 3 T33: 0.3186 T12: -0.0481 REMARK 3 T13: 0.0070 T23: -0.1193 REMARK 3 L TENSOR REMARK 3 L11: 4.5841 L22: 4.5995 REMARK 3 L33: 3.3746 L12: -3.7796 REMARK 3 L13: -1.2268 L23: -1.1139 REMARK 3 S TENSOR REMARK 3 S11: 0.0075 S12: -1.2089 S13: 0.9701 REMARK 3 S21: 0.7502 S22: -0.1450 S23: -0.3643 REMARK 3 S31: -0.2086 S32: 0.2445 S33: 0.2940 REMARK 3 TLS GROUP : 7 REMARK 3 SELECTION: (CHAIN C AND RESID 49:68) REMARK 3 ORIGIN FOR THE GROUP (A): 35.5592 -43.4400 -4.3259 REMARK 3 T TENSOR REMARK 3 T11: 0.2425 T22: 0.3491 REMARK 3 T33: 0.3366 T12: -0.0131 REMARK 3 T13: -0.0408 T23: -0.0289 REMARK 3 L TENSOR REMARK 3 L11: 2.5298 L22: 4.9143 REMARK 3 L33: 7.2477 L12: 2.8219 REMARK 3 L13: 2.2177 L23: 4.9613 REMARK 3 S TENSOR REMARK 3 S11: -0.1401 S12: 0.0190 S13: 0.1294 REMARK 3 S21: -0.5558 S22: -0.2929 S23: 0.8470 REMARK 3 S31: -0.0681 S32: -0.6314 S33: 0.4715 REMARK 3 TLS GROUP : 8 REMARK 3 SELECTION: (CHAIN C AND RESID 69:75) REMARK 3 ORIGIN FOR THE GROUP (A): 38.5565 -61.2848 -3.6421 REMARK 3 T TENSOR REMARK 3 T11: 0.6741 T22: 0.4030 REMARK 3 T33: 0.5522 T12: -0.1183 REMARK 3 T13: 0.0022 T23: -0.0816 REMARK 3 L TENSOR REMARK 3 L11: 6.6185 L22: 7.5208 REMARK 3 L33: 5.2356 L12: -6.8088 REMARK 3 L13: 5.3404 L23: -6.1884 REMARK 3 S TENSOR REMARK 3 S11: 0.8516 S12: 0.4083 S13: -2.1684 REMARK 3 S21: 0.0537 S22: 0.4616 S23: 1.0350 REMARK 3 S31: 1.7943 S32: -0.1539 S33: -1.3199 REMARK 3 TLS GROUP : 9 REMARK 3 SELECTION: (CHAIN A AND RESID 0:3) REMARK 3 ORIGIN FOR THE GROUP (A): 64.4751 -60.3535 -13.5233 REMARK 3 T TENSOR REMARK 3 T11: 0.4543 T22: 0.8875 REMARK 3 T33: 0.5164 T12: 0.0963 REMARK 3 T13: -0.0581 T23: 0.0524 REMARK 3 L TENSOR REMARK 3 L11: 8.0968 L22: 2.8489 REMARK 3 L33: 3.0672 L12: -0.0921 REMARK 3 L13: -3.1980 L23: -1.2059 REMARK 3 S TENSOR REMARK 3 S11: -0.1480 S12: 0.6880 S13: 2.7291 REMARK 3 S21: -0.9215 S22: 0.3211 S23: 0.5219 REMARK 3 S31: 1.2278 S32: -1.2954 S33: -0.1537 REMARK 3 TLS GROUP : 10 REMARK 3 SELECTION: (CHAIN A AND RESID 4:7) REMARK 3 ORIGIN FOR THE GROUP (A): 59.2438 -56.3979 1.8433 REMARK 3 T TENSOR REMARK 3 T11: 0.5297 T22: 0.4597 REMARK 3 T33: 0.5072 T12: 0.0476 REMARK 3 T13: 0.0921 T23: 0.0400 REMARK 3 L TENSOR REMARK 3 L11: 5.1386 L22: 5.5731 REMARK 3 L33: 5.7754 L12: -5.3261 REMARK 3 L13: -5.2443 L23: 5.5853 REMARK 3 S TENSOR REMARK 3 S11: -0.2769 S12: 0.6582 S13: -0.7013 REMARK 3 S21: 0.8720 S22: -0.1012 S23: -0.4736 REMARK 3 S31: 1.8328 S32: -0.7257 S33: 0.4447 REMARK 3 TLS GROUP : 11 REMARK 3 SELECTION: (CHAIN A AND RESID 8:12) REMARK 3 ORIGIN FOR THE GROUP (A): 43.9990 -50.0072 6.4153 REMARK 3 T TENSOR REMARK 3 T11: 0.2170 T22: 0.3093 REMARK 3 T33: 0.2497 T12: -0.0486 REMARK 3 T13: 0.0343 T23: -0.0182 REMARK 3 L TENSOR REMARK 3 L11: 4.2634 L22: 9.9443 REMARK 3 L33: 5.8445 L12: 2.5825 REMARK 3 L13: -1.5629 L23: 1.1750 REMARK 3 S TENSOR REMARK 3 S11: 0.2893 S12: -0.4281 S13: -0.2635 REMARK 3 S21: 0.4140 S22: -0.6385 S23: 0.3521 REMARK 3 S31: 0.2495 S32: -0.1770 S33: 0.3029 REMARK 3 TLS GROUP : 12 REMARK 3 SELECTION: (CHAIN A AND RESID 13:16) REMARK 3 ORIGIN FOR THE GROUP (A): 36.0281 -66.0708 7.8025 REMARK 3 T TENSOR REMARK 3 T11: 0.6065 T22: 0.4839 REMARK 3 T33: 0.4939 T12: -0.1384 REMARK 3 T13: 0.1240 T23: -0.0115 REMARK 3 L TENSOR REMARK 3 L11: 5.1106 L22: 5.5875 REMARK 3 L33: 6.7929 L12: 1.9826 REMARK 3 L13: -3.2205 L23: -5.7615 REMARK 3 S TENSOR REMARK 3 S11: -0.5192 S12: -0.0466 S13: -0.6770 REMARK 3 S21: -1.1497 S22: 0.4597 S23: 0.6068 REMARK 3 S31: 1.9723 S32: 0.3210 S33: -0.0972 REMARK 3 TLS GROUP : 13 REMARK 3 SELECTION: (CHAIN B AND RESID 0:3) REMARK 3 ORIGIN FOR THE GROUP (A): 33.2235 -60.7392 14.9938 REMARK 3 T TENSOR REMARK 3 T11: 0.4052 T22: 0.5641 REMARK 3 T33: 0.4951 T12: -0.0506 REMARK 3 T13: 0.0904 T23: 0.0219 REMARK 3 L TENSOR REMARK 3 L11: 7.7633 L22: 3.9534 REMARK 3 L33: 3.8142 L12: 1.0531 REMARK 3 L13: -2.2499 L23: 3.1368 REMARK 3 S TENSOR REMARK 3 S11: -1.0377 S12: 0.1136 S13: 0.0159 REMARK 3 S21: -0.7557 S22: 0.6458 S23: 0.0217 REMARK 3 S31: 0.0992 S32: 0.5757 S33: 0.3262 REMARK 3 TLS GROUP : 14 REMARK 3 SELECTION: (CHAIN B AND RESID 4:7) REMARK 3 ORIGIN FOR THE GROUP (A): 45.7169 -60.2586 6.7221 REMARK 3 T TENSOR REMARK 3 T11: 0.3088 T22: 0.3916 REMARK 3 T33: 0.4010 T12: 0.0431 REMARK 3 T13: 0.0744 T23: 0.0259 REMARK 3 L TENSOR REMARK 3 L11: 7.7431 L22: 2.9687 REMARK 3 L33: 4.7086 L12: 2.3717 REMARK 3 L13: -5.9992 L23: -2.2969 REMARK 3 S TENSOR REMARK 3 S11: -0.2031 S12: -0.9018 S13: 0.1204 REMARK 3 S21: 0.1308 S22: -0.0470 S23: 0.2031 REMARK 3 S31: 0.6969 S32: 1.2059 S33: 0.2998 REMARK 3 TLS GROUP : 15 REMARK 3 SELECTION: (CHAIN B AND RESID 8:11) REMARK 3 ORIGIN FOR THE GROUP (A): 52.7785 -49.0363 -3.8176 REMARK 3 T TENSOR REMARK 3 T11: 0.2374 T22: 0.3108 REMARK 3 T33: 0.2355 T12: -0.0026 REMARK 3 T13: 0.0278 T23: 0.0232 REMARK 3 L TENSOR REMARK 3 L11: 2.0662 L22: 2.6208 REMARK 3 L33: 2.7175 L12: -0.2185 REMARK 3 L13: 1.7407 L23: 0.8060 REMARK 3 S TENSOR REMARK 3 S11: 0.0831 S12: 1.0614 S13: -0.0988 REMARK 3 S21: -0.3591 S22: -0.0525 S23: -0.1211 REMARK 3 S31: 0.3308 S32: 0.2819 S33: -0.1071 REMARK 3 TLS GROUP : 16 REMARK 3 SELECTION: (CHAIN B AND RESID 12:15) REMARK 3 ORIGIN FOR THE GROUP (A): 67.6150 -55.1307 -3.2853 REMARK 3 T TENSOR REMARK 3 T11: 0.3064 T22: 0.5094 REMARK 3 T33: 0.4579 T12: 0.1736 REMARK 3 T13: 0.0077 T23: -0.0121 REMARK 3 L TENSOR REMARK 3 L11: 3.1310 L22: 4.7905 REMARK 3 L33: 2.5867 L12: -3.0011 REMARK 3 L13: 1.2684 L23: 0.7676 REMARK 3 S TENSOR REMARK 3 S11: 0.0635 S12: 0.7850 S13: 0.0299 REMARK 3 S21: 0.9881 S22: 0.0161 S23: -1.0556 REMARK 3 S31: 0.5412 S32: 0.6418 S33: -0.3077 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 4Y60 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 08-MAR-15. REMARK 100 THE DEPOSITION ID IS D_1000206393. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 15-OCT-12 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 5.0 REMARK 200 NUMBER OF CRYSTALS USED : NULL REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : NSLS REMARK 200 BEAMLINE : X29A REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.075 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 1 REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 23871 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.750 REMARK 200 RESOLUTION RANGE LOW (A) : 50.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 100.0 REMARK 200 DATA REDUNDANCY : 24.00 REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : NULL REMARK 200
FOR THE DATA SET : 19.9400 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : NULL REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200
FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 57.65 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.90 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1M MMT BUFFER PH 5.0, 25% (W/V) PEG REMARK 280 1500, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 298K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 64 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+1/3 REMARK 290 3555 -X+Y,-X,Z+2/3 REMARK 290 4555 -X,-Y,Z REMARK 290 5555 Y,-X+Y,Z+1/3 REMARK 290 6555 X-Y,X,Z+2/3 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 10.80567 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 21.61133 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 5 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 10.80567 REMARK 290 SMTRY1 6 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 21.61133 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 4070 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 10440 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -17.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: C, A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 ARG C 76 REMARK 465 LYS C 77 REMARK 465 LYS C 78 REMARK 465 GLN C 79 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 DT B 16 C5' C4' O4' C3' O3' C2' C1' REMARK 470 DT B 16 N1 C2 O2 N3 C4 O4 C5 REMARK 470 DT B 16 C7 C6 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 NE2 GLN C 24 O HOH C 101 2.18 REMARK 500 O HOH A 127 O HOH A 128 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 DC B 12 O3' DC B 12 C3' -0.037 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DA A 1 O4' - C1' - N9 ANGL. DEV. = 1.8 DEGREES REMARK 500 DC A 2 O4' - C1' - N1 ANGL. DEV. = 3.7 DEGREES REMARK 500 DT A 3 O3' - P - OP2 ANGL. DEV. = -25.4 DEGREES REMARK 500 DT A 3 O3' - P - OP1 ANGL. DEV. = -18.6 DEGREES REMARK 500 DT A 3 OP1 - P - OP2 ANGL. DEV. = 11.3 DEGREES REMARK 500 DT A 8 C5 - C4 - O4 ANGL. DEV. = -4.7 DEGREES REMARK 500 DT A 9 O4' - C1' - N1 ANGL. DEV. = -4.8 DEGREES REMARK 500 DG A 10 O4' - C1' - N9 ANGL. DEV. = -4.9 DEGREES REMARK 500 DG A 14 O4' - C1' - N9 ANGL. DEV. = -4.4 DEGREES REMARK 500 DG B 0 O4' - C1' - N9 ANGL. DEV. = 2.5 DEGREES REMARK 500 DC B 2 O4' - C1' - N1 ANGL. DEV. = -6.8 DEGREES REMARK 500 DC B 3 O4' - C1' - N1 ANGL. DEV. = -4.5 DEGREES REMARK 500 DG B 5 P - O5' - C5' ANGL. DEV. = -10.1 DEGREES REMARK 500 DG B 5 C1' - O4' - C4' ANGL. DEV. = -7.3 DEGREES REMARK 500 DG B 5 O4' - C1' - N9 ANGL. DEV. = 2.3 DEGREES REMARK 500 DT B 10 C1' - O4' - C4' ANGL. DEV. = -6.3 DEGREES REMARK 500 DT B 10 O4' - C1' - N1 ANGL. DEV. = -4.7 DEGREES REMARK 500 DT B 13 O4' - C1' - N1 ANGL. DEV. = -6.8 DEGREES REMARK 500 DA B 14 C1' - O4' - C4' ANGL. DEV. = -6.1 DEGREES REMARK 500 DA B 14 C3' - C2' - C1' ANGL. DEV. = -8.2 DEGREES REMARK 500 DG B 15 O4' - C1' - N9 ANGL. DEV. = 2.3 DEGREES REMARK 500 REMARK 500 REMARK: NULL DBREF 4Y60 C 1 79 UNP P43680 SOX18_MOUSE 77 155 DBREF 4Y60 A 0 16 PDB 4Y60 4Y60 0 16 DBREF 4Y60 B 0 16 PDB 4Y60 4Y60 0 16 SEQADV 4Y60 GLY C 0 UNP P43680 EXPRESSION TAG SEQRES 1 C 80 GLY LEU ARG ILE ARG ARG PRO MET ASN ALA PHE MET VAL SEQRES 2 C 80 TRP ALA LYS ASP GLU ARG LYS ARG LEU ALA GLN GLN ASN SEQRES 3 C 80 PRO ASP LEU HIS ASN ALA VAL LEU SER LYS MET LEU GLY SEQRES 4 C 80 LYS ALA TRP LYS GLU LEU ASN THR ALA GLU LYS ARG PRO SEQRES 5 C 80 PHE VAL GLU GLU ALA GLU ARG LEU ARG VAL GLN HIS LEU SEQRES 6 C 80 ARG ASP HIS PRO ASN TYR LYS TYR ARG PRO ARG ARG LYS SEQRES 7 C 80 LYS GLN SEQRES 1 A 17 DC DA DC DT DA DG DC DA DT DT DG DT DC SEQRES 2 A 17 DT DG DG DG SEQRES 1 B 17 DG DC DC DC DA DG DA DC DA DA DT DG DC SEQRES 2 B 17 DT DA DG DT FORMUL 4 HOH *194(H2 O) HELIX 1 AA1 ASN C 8 ASN C 25 1 18 HELIX 2 AA2 HIS C 29 LEU C 44 1 16 HELIX 3 AA3 ASN C 45 HIS C 67 1 23 CRYST1 111.942 111.942 32.417 90.00 90.00 120.00 P 64 6 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.008933 0.005158 0.000000 0.00000 SCALE2 0.000000 0.010315 0.000000 0.00000 SCALE3 0.000000 0.000000 0.030848 0.00000 ATOM 1 N GLY C 0 43.447 -56.622 -20.561 1.00 56.53 N ANISOU 1 N GLY C 0 9838 7489 4152 -1159 -115 -2655 N ATOM 2 CA GLY C 0 43.998 -55.735 -19.553 1.00 53.30 C ANISOU 2 CA GLY C 0 9285 7131 3835 -1180 31 -2430 C ATOM 3 C GLY C 0 44.601 -56.468 -18.370 1.00 51.18 C ANISOU 3 C GLY C 0 8774 6757 3915 -978 238 -2574 C ATOM 4 O GLY C 0 44.612 -57.691 -18.325 1.00 61.46 O ANISOU 4 O GLY C 0 10038 7904 5411 -818 280 -2829 O ATOM 5 N LEU C 1 45.093 -55.708 -17.397 1.00 48.43 N ANISOU 5 N LEU C 1 8195 6483 3725 -930 345 -2358 N ATOM 6 CA LEU C 1 45.757 -56.287 -16.239 1.00 48.26 C ANISOU 6 CA LEU C 1 7864 6405 4067 -656 509 -2403 C ATOM 7 C LEU C 1 44.774 -56.663 -15.121 1.00 51.06 C ANISOU 7 C LEU C 1 8103 6451 4845 -523 279 -2216 C ATOM 8 O LEU C 1 43.585 -56.335 -15.173 1.00 44.76 O ANISOU 8 O LEU C 1 7409 5495 4102 -661 2 -2058 O ATOM 9 CB LEU C 1 46.803 -55.302 -15.697 1.00 52.69 C ANISOU 9 CB LEU C 1 8195 7226 4600 -653 735 -2302 C ATOM 10 CG LEU C 1 47.984 -55.078 -16.647 1.00 58.19 C ANISOU 10 CG LEU C 1 8934 8211 4965 -753 1056 -2525 C ATOM 11 CD1 LEU C 1 48.665 -53.760 -16.351 1.00 63.13 C ANISOU 11 CD1 LEU C 1 9388 9051 5546 -864 1216 -2348 C ATOM 12 CD2 LEU C 1 48.959 -56.222 -16.518 1.00 61.30 C ANISOU 12 CD2 LEU C 1 9138 8605 5549 -471 1244 -2804 C ATOM 13 N ARG C 2 45.279 -57.349 -14.102 1.00 50.85 N ANISOU 13 N ARG C 2 7865 6340 5117 -252 397 -2241 N ATOM 14 CA ARG C 2 44.423 -57.788 -13.008 1.00 49.93 C ANISOU 14 CA ARG C 2 7670 5929 5374 -130 241 -2061 C ATOM 15 C ARG C 2 43.818 -56.591 -12.282 1.00 46.55 C ANISOU 15 C ARG C 2 7128 5542 5018 -260 90 -1746 C ATOM 16 O ARG C 2 44.428 -55.507 -12.192 1.00 37.42 O ANISOU 16 O ARG C 2 5852 4651 3716 -334 171 -1652 O ATOM 17 CB ARG C 2 45.201 -58.678 -12.030 1.00 53.30 C ANISOU 17 CB ARG C 2 7923 6280 6047 209 400 -2106 C ATOM 18 CG ARG C 2 46.423 -58.000 -11.414 1.00 57.51 C ANISOU 18 CG ARG C 2 8202 7130 6520 342 567 -2073 C ATOM 19 CD ARG C 2 47.108 -58.889 -10.376 1.00 64.10 C ANISOU 19 CD ARG C 2 8876 7881 7597 722 650 -2095 C ATOM 20 NE ARG C 2 46.273 -59.089 -9.194 1.00 59.81 N ANISOU 20 NE ARG C 2 8321 7101 7303 814 511 -1811 N ATOM 21 CZ ARG C 2 46.327 -58.332 -8.100 1.00 58.02 C ANISOU 21 CZ ARG C 2 7905 7016 7123 863 473 -1586 C ATOM 22 NH1 ARG C 2 47.181 -57.317 -8.026 1.00 48.05 N ANISOU 22 NH1 ARG C 2 6427 6116 5715 837 554 -1624 N ATOM 23 NH2 ARG C 2 45.519 -58.588 -7.077 1.00 56.74 N ANISOU 23 NH2 ARG C 2 7766 6633 7161 922 376 -1347 N ATOM 24 N ILE C 3 42.616 -56.786 -11.755 1.00 40.17 N ANISOU 24 N ILE C 3 6337 4458 4467 -298 -108 -1613 N ATOM 25 CA ILE C 3 41.932 -55.721 -11.032 1.00 34.42 C ANISOU 25 CA ILE C 3 5479 3737 3863 -424 -256 -1355 C ATOM 26 C ILE C 3 42.430 -55.606 -9.606 1.00 32.32 C ANISOU 26 C ILE C 3 4961 3538 3782 -234 -135 -1206 C ATOM 27 O ILE C 3 42.454 -56.592 -8.876 1.00 33.65 O ANISOU 27 O ILE C 3 5111 3532 4141 -27 -65 -1206 O ATOM 28 CB ILE C 3 40.430 -55.972 -10.966 1.00 33.67 C ANISOU 28 CB ILE C 3 5460 3326 4008 -549 -498 -1317 C ATOM 29 CG1 ILE C 3 39.913 -56.357 -12.350 1.00 47.20 C ANISOU 29 CG1 ILE C 3 7423 4959 5553 -684 -646 -1525 C ATOM 30 CG2 ILE C 3 39.741 -54.731 -10.415 1.00 31.25 C ANISOU 30 CG2 ILE C 3 5006 3052 3815 -709 -663 -1099 C ATOM 31 CD1 ILE C 3 40.220 -55.331 -13.414 1.00 50.63 C ANISOU 31 CD1 ILE C 3 7983 5656 5598 -855 -718 -1508 C ATOM 32 N ARG C 4 42.815 -54.398 -9.208 1.00 30.38 N ANISOU 32 N ARG C 4 4530 3536 3476 -302 -112 -1078 N ATOM 33 CA ARG C 4 43.394 -54.166 -7.888 1.00 29.21 C ANISOU 33 CA ARG C 4 4118 3528 3454 -121 -6 -976 C ATOM 34 C ARG C 4 42.352 -53.586 -6.934 1.00 27.60 C ANISOU 34 C ARG C 4 3792 3215 3481 -227 -150 -777 C ATOM 35 O ARG C 4 41.308 -53.116 -7.371 1.00 30.63 O ANISOU 35 O ARG C 4 4252 3456 3931 -457 -333 -727 O ATOM 36 CB ARG C 4 44.569 -53.169 -8.015 1.00 30.09 C ANISOU 36 CB ARG C 4 4046 4002 3386 -137 146 -1028 C ATOM 37 CG ARG C 4 45.699 -53.751 -8.876 1.00 36.17 C ANISOU 37 CG ARG C 4 4891 4904 3946 -32 339 -1272 C ATOM 38 CD ARG C 4 46.809 -52.745 -9.136 1.00 37.91 C ANISOU 38 CD ARG C 4 4938 5462 4004 -105 530 -1363 C ATOM 39 NE ARG C 4 47.957 -53.423 -9.749 1.00 51.91 N ANISOU 39 NE ARG C 4 6721 7367 5635 32 749 -1645 N ATOM 40 CZ ARG C 4 48.876 -54.102 -9.058 1.00 63.15 C ANISOU 40 CZ ARG C 4 7945 8880 7169 352 857 -1794 C ATOM 41 NH1 ARG C 4 48.790 -54.192 -7.731 1.00 55.21 N ANISOU 41 NH1 ARG C 4 6751 7862 6363 569 764 -1657 N ATOM 42 NH2 ARG C 4 49.881 -54.698 -9.689 1.00 68.00 N ANISOU 42 NH2 ARG C 4 8549 9600 7689 465 1050 -2091 N ATOM 43 N ARG C 5 42.646 -53.570 -5.635 1.00 26.84 N ANISOU 43 N ARG C 5 3493 3207 3500 -58 -78 -682 N ATOM 44 CA ARG C 5 41.745 -52.922 -4.670 1.00 27.35 C ANISOU 44 CA ARG C 5 3406 3220 3767 -177 -174 -527 C ATOM 45 C ARG C 5 41.775 -51.415 -4.850 1.00 25.12 C ANISOU 45 C ARG C 5 2942 3140 3464 -386 -232 -498 C ATOM 46 O ARG C 5 42.818 -50.863 -5.146 1.00 26.12 O ANISOU 46 O ARG C 5 2969 3527 3430 -356 -119 -567 O ATOM 47 CB ARG C 5 42.197 -53.173 -3.210 1.00 23.86 C ANISOU 47 CB ARG C 5 2791 2897 3378 63 -68 -440 C ATOM 48 CG ARG C 5 42.498 -54.643 -2.896 1.00 25.17 C ANISOU 48 CG ARG C 5 3131 2889 3541 347 20 -435 C ATOM 49 CD ARG C 5 42.588 -54.856 -1.380 1.00 30.71 C ANISOU 49 CD ARG C 5 3729 3652 4287 548 74 -281 C ATOM 50 NE ARG C 5 41.272 -54.655 -0.752 1.00 27.20 N ANISOU 50 NE ARG C 5 3291 3012 4033 335 27 -152 N ATOM 51 CZ ARG C 5 41.073 -54.525 0.552 1.00 32.44 C ANISOU 51 CZ ARG C 5 3850 3751 4723 395 73 -17 C ATOM 52 NH1 ARG C 5 42.110 -54.577 1.382 1.00 27.42 N ANISOU 52 NH1 ARG C 5 3105 3395 3918 690 130 21 N ATOM 53 NH2 ARG C 5 39.838 -54.347 1.018 1.00 29.44 N ANISOU 53 NH2 ARG C 5 3469 3180 4537 162 61 54 N ATOM 54 N PRO C 6 40.640 -50.743 -4.622 1.00 25.12 N ANISOU 54 N PRO C 6 2876 3004 3664 -598 -392 -413 N ATOM 55 CA PRO C 6 40.628 -49.269 -4.678 1.00 28.83 C ANISOU 55 CA PRO C 6 3153 3624 4177 -785 -453 -372 C ATOM 56 C PRO C 6 41.425 -48.667 -3.511 1.00 28.92 C ANISOU 56 C PRO C 6 2837 3929 4222 -674 -304 -373 C ATOM 57 O PRO C 6 41.509 -49.281 -2.419 1.00 29.58 O ANISOU 57 O PRO C 6 2835 4052 4351 -492 -231 -355 O ATOM 58 CB PRO C 6 39.139 -48.924 -4.540 1.00 27.75 C ANISOU 58 CB PRO C 6 3025 3258 4261 -948 -626 -310 C ATOM 59 CG PRO C 6 38.526 -50.120 -3.848 1.00 28.23 C ANISOU 59 CG PRO C 6 3139 3095 4492 -876 -627 -318 C ATOM 60 CD PRO C 6 39.319 -51.320 -4.317 1.00 25.59 C ANISOU 60 CD PRO C 6 3021 2744 3959 -679 -511 -378 C ATOM 61 N MET C 7 42.019 -47.497 -3.725 1.00 25.20 N ANISOU 61 N MET C 7 2193 3661 3721 -778 -254 -398 N ATOM 62 CA MET C 7 42.882 -46.905 -2.697 1.00 25.07 C ANISOU 62 CA MET C 7 1977 3856 3693 -598 -107 -384 C ATOM 63 C MET C 7 42.017 -46.321 -1.616 1.00 23.51 C ANISOU 63 C MET C 7 1847 3485 3599 -559 -191 -151 C ATOM 64 O MET C 7 41.034 -45.616 -1.928 1.00 24.44 O ANISOU 64 O MET C 7 2123 3489 3676 -681 -291 -31 O ATOM 65 CB MET C 7 43.707 -45.744 -3.256 1.00 27.57 C ANISOU 65 CB MET C 7 2282 4256 3938 -647 -12 -396 C ATOM 66 CG MET C 7 44.953 -46.141 -3.956 1.00 29.95 C ANISOU 66 CG MET C 7 2478 4860 4043 -644 181 -623 C ATOM 67 SD MET C 7 45.881 -44.692 -4.448 1.00 32.31 S ANISOU 67 SD MET C 7 2776 5203 4296 -729 321 -633 S ATOM 68 CE MET C 7 44.832 -44.142 -5.796 1.00 45.09 C ANISOU 68 CE MET C 7 4585 6634 5912 -1088 192 -492 C ATOM 69 N ASN C 8 42.374 -46.573 -0.353 1.00 24.24 N ANISOU 69 N ASN C 8 3062 3176 2973 -473 -341 -399 N ATOM 70 CA ASN C 8 41.678 -45.928 0.752 1.00 22.69 C ANISOU 70 CA ASN C 8 2775 3274 2572 -612 -398 -346 C ATOM 71 C ASN C 8 42.202 -44.497 0.960 1.00 24.80 C ANISOU 71 C ASN C 8 2956 3656 2813 -493 -320 -418 C ATOM 72 O ASN C 8 43.123 -44.062 0.268 1.00 23.02 O ANISOU 72 O ASN C 8 2748 3288 2710 -318 -254 -445 O ATOM 73 CB ASN C 8 41.726 -46.759 2.062 1.00 21.51 C ANISOU 73 CB ASN C 8 2575 3177 2419 -848 -563 -110 C ATOM 74 CG ASN C 8 43.113 -46.836 2.667 1.00 24.55 C ANISOU 74 CG ASN C 8 2897 3440 2989 -822 -631 89 C ATOM 75 OD1 ASN C 8 43.852 -45.855 2.669 1.00 24.83 O ANISOU 75 OD1 ASN C 8 2890 3523 3022 -698 -550 25 O ATOM 76 ND2 ASN C 8 43.450 -47.994 3.239 1.00 25.59 N ANISOU 76 ND2 ASN C 8 3000 3420 3305 -965 -807 375 N ATOM 77 N ALA C 9 41.621 -43.776 1.917 1.00 24.80 N ANISOU 77 N ALA C 9 2846 3917 2661 -611 -317 -477 N ATOM 78 CA ALA C 9 41.950 -42.348 2.054 1.00 24.16 C ANISOU 78 CA ALA C 9 2674 3896 2610 -506 -226 -613 C ATOM 79 C ALA C 9 43.412 -42.125 2.325 1.00 27.12 C ANISOU 79 C ALA C 9 3054 4164 3086 -458 -239 -511 C ATOM 80 O ALA C 9 43.994 -41.176 1.827 1.00 23.85 O ANISOU 80 O ALA C 9 2627 3660 2774 -303 -174 -573 O ATOM 81 CB ALA C 9 41.123 -41.704 3.161 1.00 27.13 C ANISOU 81 CB ALA C 9 2899 4570 2840 -675 -184 -780 C ATOM 82 N PHE C 10 43.985 -42.940 3.198 1.00 22.02 N ANISOU 82 N PHE C 10 2394 3556 2415 -623 -345 -316 N ATOM 83 CA PHE C 10 45.399 -42.784 3.500 1.00 21.80 C ANISOU 83 CA PHE C 10 2335 3453 2494 -595 -378 -168 C ATOM 84 C PHE C 10 46.223 -43.027 2.251 1.00 23.68 C ANISOU 84 C PHE C 10 2646 3389 2961 -333 -332 -141 C ATOM 85 O PHE C 10 47.166 -42.278 1.969 1.00 21.56 O ANISOU 85 O PHE C 10 2353 3075 2763 -216 -280 -151 O ATOM 86 CB PHE C 10 45.826 -43.727 4.636 1.00 22.01 C ANISOU 86 CB PHE C 10 2289 3583 2492 -850 -549 133 C ATOM 87 CG PHE C 10 47.315 -43.838 4.798 1.00 23.54 C ANISOU 87 CG PHE C 10 2423 3653 2867 -800 -618 369 C ATOM 88 CD1 PHE C 10 48.026 -42.827 5.416 1.00 21.89 C ANISOU 88 CD1 PHE C 10 2135 3639 2542 -888 -591 348 C ATOM 89 CD2 PHE C 10 48.005 -44.939 4.308 1.00 23.63 C ANISOU 89 CD2 PHE C 10 2435 3341 3201 -665 -696 585 C ATOM 90 CE1 PHE C 10 49.412 -42.910 5.556 1.00 24.87 C ANISOU 90 CE1 PHE C 10 2435 3938 3076 -855 -663 595 C ATOM 91 CE2 PHE C 10 49.373 -45.051 4.460 1.00 25.62 C ANISOU 91 CE2 PHE C 10 2580 3482 3671 -601 -757 815 C ATOM 92 CZ PHE C 10 50.089 -44.029 5.073 1.00 28.00 C ANISOU 92 CZ PHE C 10 2804 4023 3810 -698 -749 846 C ATOM 93 N MET C 11 45.894 -44.060 1.487 1.00 23.32 N ANISOU 93 N MET C 11 2677 3162 3020 -270 -336 -138 N ATOM 94 CA MET C 11 46.721 -44.366 0.319 1.00 22.17 C ANISOU 94 CA MET C 11 2567 2781 3075 -67 -252 -186 C ATOM 95 C MET C 11 46.606 -43.271 -0.763 1.00 23.58 C ANISOU 95 C MET C 11 2770 3033 3155 56 -129 -363 C ATOM 96 O MET C 11 47.585 -42.944 -1.453 1.00 22.60 O ANISOU 96 O MET C 11 2622 2852 3114 178 -59 -380 O ATOM 97 CB MET C 11 46.389 -45.764 -0.242 1.00 23.55 C ANISOU 97 CB MET C 11 2805 2734 3409 -67 -258 -218 C ATOM 98 CG MET C 11 46.623 -46.906 0.754 1.00 27.86 C ANISOU 98 CG MET C 11 3294 3128 4164 -189 -427 43 C ATOM 99 SD MET C 11 48.397 -47.048 0.988 1.00 34.22 S ANISOU 99 SD MET C 11 3948 3735 5318 -45 -453 242 S ATOM 100 CE MET C 11 48.613 -48.238 2.247 1.00 41.78 C ANISOU 100 CE MET C 11 4780 4549 6547 -234 -721 677 C ATOM 101 N VAL C 12 45.406 -42.730 -0.947 1.00 21.48 N ANISOU 101 N VAL C 12 2524 2908 2731 6 -119 -461 N ATOM 102 CA VAL C 12 45.213 -41.601 -1.884 1.00 22.57 C ANISOU 102 CA VAL C 12 2637 3113 2824 88 -63 -530 C ATOM 103 C VAL C 12 46.086 -40.408 -1.528 1.00 20.68 C ANISOU 103 C VAL C 12 2325 2879 2652 146 -60 -488 C ATOM 104 O VAL C 12 46.743 -39.818 -2.386 1.00 23.47 O ANISOU 104 O VAL C 12 2660 3216 3043 222 -29 -458 O ATOM 105 CB VAL C 12 43.767 -41.105 -1.895 1.00 27.39 C ANISOU 105 CB VAL C 12 3210 3852 3344 34 -83 -589 C ATOM 106 CG1 VAL C 12 43.649 -39.824 -2.770 1.00 29.21 C ANISOU 106 CG1 VAL C 12 3360 4110 3629 112 -78 -563 C ATOM 107 CG2 VAL C 12 42.885 -42.179 -2.454 1.00 26.32 C ANISOU 107 CG2 VAL C 12 3148 3743 3109 -50 -89 -622 C ATOM 108 N TRP C 13 46.103 -40.076 -0.246 1.00 18.16 N ANISOU 108 N TRP C 13 1957 2619 2323 63 -94 -490 N ATOM 109 CA TRP C 13 46.906 -38.961 0.251 1.00 20.50 C ANISOU 109 CA TRP C 13 2188 2926 2675 66 -87 -489 C ATOM 110 C TRP C 13 48.396 -39.269 0.161 1.00 23.25 C ANISOU 110 C TRP C 13 2538 3213 3083 109 -97 -344 C ATOM 111 O TRP C 13 49.207 -38.386 -0.152 1.00 24.94 O ANISOU 111 O TRP C 13 2719 3405 3353 161 -82 -313 O ATOM 112 CB TRP C 13 46.485 -38.672 1.697 1.00 21.99 C ANISOU 112 CB TRP C 13 2308 3269 2778 -110 -94 -590 C ATOM 113 CG TRP C 13 47.350 -37.728 2.435 1.00 22.52 C ANISOU 113 CG TRP C 13 2311 3382 2864 -187 -80 -627 C ATOM 114 CD1 TRP C 13 47.278 -36.361 2.459 1.00 21.60 C ANISOU 114 CD1 TRP C 13 2129 3208 2869 -162 -25 -797 C ATOM 115 CD2 TRP C 13 48.408 -38.090 3.320 1.00 22.86 C ANISOU 115 CD2 TRP C 13 2328 3535 2822 -338 -137 -479 C ATOM 116 NE1 TRP C 13 48.245 -35.857 3.295 1.00 22.97 N ANISOU 116 NE1 TRP C 13 2265 3461 3002 -304 -23 -810 N ATOM 117 CE2 TRP C 13 48.966 -36.904 3.814 1.00 20.26 C ANISOU 117 CE2 TRP C 13 1940 3251 2506 -420 -98 -592 C ATOM 118 CE3 TRP C 13 48.951 -39.320 3.724 1.00 21.72 C ANISOU 118 CE3 TRP C 13 2181 3433 2637 -422 -236 -229 C ATOM 119 CZ2 TRP C 13 50.017 -36.898 4.734 1.00 25.08 C ANISOU 119 CZ2 TRP C 13 2497 4025 3008 -621 -150 -470 C ATOM 120 CZ3 TRP C 13 49.999 -39.319 4.593 1.00 23.78 C ANISOU 120 CZ3 TRP C 13 2364 3825 2847 -588 -309 -53 C ATOM 121 CH2 TRP C 13 50.529 -38.121 5.109 1.00 24.31 C ANISOU 121 CH2 TRP C 13 2379 4012 2845 -706 -265 -171 C ATOM 122 N ALA C 14 48.763 -40.518 0.472 1.00 19.57 N ANISOU 122 N ALA C 14 2083 2704 2646 82 -136 -233 N ATOM 123 CA ALA C 14 50.180 -40.885 0.570 1.00 19.74 C ANISOU 123 CA ALA C 14 2045 2658 2796 128 -156 -70 C ATOM 124 C ALA C 14 50.908 -40.817 -0.764 1.00 26.00 C ANISOU 124 C ALA C 14 2833 3365 3680 298 -60 -115 C ATOM 125 O ALA C 14 52.135 -40.677 -0.810 1.00 26.45 O ANISOU 125 O ALA C 14 2806 3413 3828 351 -48 -17 O ATOM 126 CB ALA C 14 50.345 -42.260 1.230 1.00 22.38 C ANISOU 126 CB ALA C 14 2342 2910 3251 63 -251 105 C ATOM 127 N LYS C 15 50.161 -40.897 -1.855 1.00 27.20 N ANISOU 127 N LYS C 15 3049 3512 3773 343 10 -260 N ATOM 128 CA LYS C 15 50.804 -40.856 -3.172 1.00 27.04 C ANISOU 128 CA LYS C 15 3000 3513 3761 424 116 -329 C ATOM 129 C LYS C 15 51.653 -39.626 -3.374 1.00 31.18 C ANISOU 129 C LYS C 15 3459 4138 4251 430 108 -238 C ATOM 130 O LYS C 15 52.850 -39.739 -3.643 1.00 35.80 O ANISOU 130 O LYS C 15 3957 4740 4907 484 161 -199 O ATOM 131 CB LYS C 15 49.756 -40.948 -4.267 1.00 30.77 C ANISOU 131 CB LYS C 15 3534 4064 4091 379 165 -464 C ATOM 132 CG LYS C 15 49.532 -42.336 -4.771 1.00 40.32 C ANISOU 132 CG LYS C 15 4781 5182 5355 379 252 -629 C ATOM 133 CD LYS C 15 48.363 -42.361 -5.725 1.00 37.66 C ANISOU 133 CD LYS C 15 4507 4988 4813 265 278 -742 C ATOM 134 CE LYS C 15 48.653 -41.551 -6.944 1.00 45.62 C ANISOU 134 CE LYS C 15 5451 6237 5645 196 328 -741 C ATOM 135 NZ LYS C 15 49.030 -42.435 -8.084 1.00 47.96 N ANISOU 135 NZ LYS C 15 5723 6630 5870 122 504 -996 N ATOM 136 N ASP C 16 51.069 -38.437 -3.218 1.00 30.61 N ANISOU 136 N ASP C 16 3601 3820 4211 1368 -173 96 N ATOM 137 CA ASP C 16 51.893 -37.245 -3.386 1.00 30.64 C ANISOU 137 CA ASP C 16 3799 3551 4291 1444 16 205 C ATOM 138 C ASP C 16 52.789 -37.046 -2.202 1.00 28.36 C ANISOU 138 C ASP C 16 3538 3173 4066 1175 239 76 C ATOM 139 O ASP C 16 53.903 -36.584 -2.359 1.00 31.74 O ANISOU 139 O ASP C 16 4131 3465 4462 1079 353 192 O ATOM 140 CB ASP C 16 51.088 -35.938 -3.576 1.00 32.77 C ANISOU 140 CB ASP C 16 4058 3615 4780 1731 30 262 C ATOM 141 CG ASP C 16 52.027 -34.693 -3.699 1.00 49.65 C ANISOU 141 CG ASP C 16 6501 5408 6954 1729 208 384 C ATOM 142 OD1 ASP C 16 52.972 -34.743 -4.524 1.00 50.09 O ANISOU 142 OD1 ASP C 16 6766 5438 6829 1654 213 575 O ATOM 143 OD2 ASP C 16 51.876 -33.691 -2.958 1.00 44.82 O ANISOU 143 OD2 ASP C 16 5953 4551 6526 1770 361 291 O ATOM 144 N GLU C 17 52.286 -37.320 -0.992 1.00 27.52 N ANISOU 144 N GLU C 17 3274 3140 4041 1020 300 -150 N ATOM 145 CA GLU C 17 53.095 -37.025 0.189 1.00 26.74 C ANISOU 145 CA GLU C 17 3272 2912 3976 733 474 -268 C ATOM 146 C GLU C 17 54.336 -37.877 0.237 1.00 24.52 C ANISOU 146 C GLU C 17 3041 2726 3550 494 414 -203 C ATOM 147 O GLU C 17 55.391 -37.395 0.674 1.00 25.44 O ANISOU 147 O GLU C 17 3260 2710 3698 294 503 -152 O ATOM 148 CB GLU C 17 52.312 -37.173 1.500 1.00 27.13 C ANISOU 148 CB GLU C 17 3211 3017 4081 588 578 -529 C ATOM 149 CG GLU C 17 51.681 -35.906 2.003 1.00 59.56 C ANISOU 149 CG GLU C 17 7375 6892 8363 754 794 -641 C ATOM 150 CD GLU C 17 52.659 -34.754 2.123 1.00 49.93 C ANISOU 150 CD GLU C 17 6492 5307 7175 679 903 -568 C ATOM 151 OE1 GLU C 17 53.510 -34.739 3.040 1.00 48.08 O ANISOU 151 OE1 GLU C 17 6433 4970 6864 317 958 -640 O ATOM 152 OE2 GLU C 17 52.568 -33.850 1.286 1.00 54.91 O ANISOU 152 OE2 GLU C 17 7235 5737 7892 950 896 -419 O ATOM 153 N ARG C 18 54.227 -39.134 -0.186 1.00 23.13 N ANISOU 153 N ARG C 18 2803 2767 3221 513 247 -196 N ATOM 154 CA ARG C 18 55.427 -39.980 -0.201 1.00 23.92 C ANISOU 154 CA ARG C 18 2949 2940 3199 386 198 -131 C ATOM 155 C ARG C 18 56.448 -39.395 -1.162 1.00 25.52 C ANISOU 155 C ARG C 18 3218 3079 3400 509 308 98 C ATOM 156 O ARG C 18 57.657 -39.319 -0.876 1.00 24.01 O ANISOU 156 O ARG C 18 2991 2886 3247 356 384 186 O ATOM 157 CB ARG C 18 55.080 -41.416 -0.609 1.00 20.79 C ANISOU 157 CB ARG C 18 2579 2717 2604 438 -6 -168 C ATOM 158 CG ARG C 18 56.304 -42.363 -0.538 1.00 19.99 C ANISOU 158 CG ARG C 18 2540 2662 2394 385 -53 -124 C ATOM 159 CD ARG C 18 55.910 -43.789 -1.037 1.00 21.56 C ANISOU 159 CD ARG C 18 2893 2951 2349 472 -272 -171 C ATOM 160 NE ARG C 18 54.924 -44.393 -0.117 1.00 23.24 N ANISOU 160 NE ARG C 18 3094 3214 2522 219 -435 -344 N ATOM 161 CZ ARG C 18 55.240 -44.994 1.030 1.00 26.62 C ANISOU 161 CZ ARG C 18 3553 3630 2931 -47 -512 -447 C ATOM 162 NH1 ARG C 18 56.524 -45.112 1.414 1.00 23.50 N ANISOU 162 NH1 ARG C 18 3168 3178 2584 -68 -490 -388 N ATOM 163 NH2 ARG C 18 54.264 -45.479 1.819 1.00 22.87 N ANISOU 163 NH2 ARG C 18 3084 3217 2387 -317 -622 -590 N ATOM 164 N LYS C 19 55.952 -38.968 -2.316 1.00 27.03 N ANISOU 164 N LYS C 19 3492 3235 3541 763 306 218 N ATOM 165 CA LYS C 19 56.811 -38.344 -3.316 1.00 30.56 C ANISOU 165 CA LYS C 19 4050 3622 3940 856 440 452 C ATOM 166 C LYS C 19 57.547 -37.121 -2.753 1.00 26.67 C ANISOU 166 C LYS C 19 3568 2948 3618 644 600 531 C ATOM 167 O LYS C 19 58.777 -36.936 -2.995 1.00 30.73 O ANISOU 167 O LYS C 19 4052 3503 4123 516 731 707 O ATOM 168 CB LYS C 19 55.962 -37.908 -4.509 1.00 41.73 C ANISOU 168 CB LYS C 19 5622 4969 5267 1123 364 565 C ATOM 169 CG LYS C 19 56.698 -37.869 -5.810 1.00 53.46 C ANISOU 169 CG LYS C 19 7293 6473 6544 1240 461 791 C ATOM 170 CD LYS C 19 56.473 -39.156 -6.585 1.00 62.09 C ANISOU 170 CD LYS C 19 8503 7728 7362 1398 332 763 C ATOM 171 CE LYS C 19 57.120 -39.069 -7.959 1.00 64.17 C ANISOU 171 CE LYS C 19 9030 7995 7357 1540 477 975 C ATOM 172 NZ LYS C 19 58.585 -38.833 -7.829 1.00 66.17 N ANISOU 172 NZ LYS C 19 9161 8321 7659 1426 800 1088 N ATOM 173 N ARG C 20 56.809 -36.257 -2.053 1.00 27.29 N ANISOU 173 N ARG C 20 3702 2824 3843 604 602 416 N ATOM 174 CA ARG C 20 57.386 -35.057 -1.459 1.00 32.05 C ANISOU 174 CA ARG C 20 4434 3174 4568 377 717 464 C ATOM 175 C ARG C 20 58.438 -35.390 -0.423 1.00 34.44 C ANISOU 175 C ARG C 20 4636 3546 4905 3 724 431 C ATOM 176 O ARG C 20 59.530 -34.811 -0.423 1.00 33.83 O ANISOU 176 O ARG C 20 4581 3409 4862 -244 786 612 O ATOM 177 CB ARG C 20 56.313 -34.192 -0.795 1.00 38.02 C ANISOU 177 CB ARG C 20 5322 3673 5451 464 739 287 C ATOM 178 CG ARG C 20 55.517 -33.338 -1.746 1.00 47.51 C ANISOU 178 CG ARG C 20 6676 4686 6691 808 720 395 C ATOM 179 CD ARG C 20 54.755 -32.260 -0.975 1.00 49.95 C ANISOU 179 CD ARG C 20 7155 4667 7158 908 800 235 C ATOM 180 NE ARG C 20 55.605 -31.637 0.040 1.00 68.69 N ANISOU 180 NE ARG C 20 9750 6807 9542 531 909 177 N ATOM 181 CZ ARG C 20 55.380 -31.695 1.354 1.00 71.40 C ANISOU 181 CZ ARG C 20 10123 7095 9911 363 990 -83 C ATOM 182 NH1 ARG C 20 54.315 -32.328 1.812 1.00 67.57 N ANISOU 182 NH1 ARG C 20 9416 6796 9461 545 1020 -306 N ATOM 183 NH2 ARG C 20 56.211 -31.107 2.210 1.00 68.91 N ANISOU 183 NH2 ARG C 20 10081 6539 9561 -29 1035 -107 N ATOM 184 N LEU C 21 58.111 -36.308 0.476 1.00 26.22 N ANISOU 184 N LEU C 21 3484 2630 3849 -80 631 223 N ATOM 185 CA LEU C 21 59.096 -36.702 1.482 1.00 26.75 C ANISOU 185 CA LEU C 21 3474 2755 3935 -436 566 210 C ATOM 186 C LEU C 21 60.353 -37.319 0.842 1.00 28.09 C ANISOU 186 C LEU C 21 3431 3152 4090 -434 556 437 C ATOM 187 O LEU C 21 61.479 -37.074 1.306 1.00 28.72 O ANISOU 187 O LEU C 21 3407 3251 4254 -729 535 572 O ATOM 188 CB LEU C 21 58.489 -37.664 2.496 1.00 24.36 C ANISOU 188 CB LEU C 21 3145 2538 3572 -529 449 -34 C ATOM 189 CG LEU C 21 57.438 -37.060 3.419 1.00 31.73 C ANISOU 189 CG LEU C 21 4250 3285 4521 -602 528 -273 C ATOM 190 CD1 LEU C 21 56.843 -38.146 4.335 1.00 31.94 C ANISOU 190 CD1 LEU C 21 4240 3454 4440 -736 437 -487 C ATOM 191 CD2 LEU C 21 58.047 -35.954 4.234 1.00 34.52 C ANISOU 191 CD2 LEU C 21 4835 3360 4922 -920 587 -270 C ATOM 192 N ALA C 22 60.170 -38.117 -0.207 1.00 25.28 N ANISOU 192 N ALA C 22 3011 2973 3623 -105 571 482 N ATOM 193 CA ALA C 22 61.295 -38.787 -0.850 1.00 26.12 C ANISOU 193 CA ALA C 22 2928 3301 3694 -10 629 662 C ATOM 194 C ALA C 22 62.212 -37.764 -1.461 1.00 33.14 C ANISOU 194 C ALA C 22 3759 4185 4649 -117 822 930 C ATOM 195 O ALA C 22 63.432 -37.920 -1.449 1.00 32.85 O ANISOU 195 O ALA C 22 3460 4329 4692 -235 887 1109 O ATOM 196 CB ALA C 22 60.817 -39.786 -1.931 1.00 27.72 C ANISOU 196 CB ALA C 22 3209 3629 3695 379 631 630 C ATOM 197 N GLN C 23 61.638 -36.692 -2.000 1.00 29.81 N ANISOU 197 N GLN C 23 3566 3558 4201 -87 905 983 N ATOM 198 CA GLN C 23 62.466 -35.745 -2.728 1.00 35.63 C ANISOU 198 CA GLN C 23 4315 4276 4945 -215 1089 1267 C ATOM 199 C GLN C 23 63.230 -34.869 -1.721 1.00 34.59 C ANISOU 199 C GLN C 23 4139 4019 4983 -698 1044 1351 C ATOM 200 O GLN C 23 64.393 -34.480 -1.945 1.00 37.44 O ANISOU 200 O GLN C 23 4316 4508 5403 -955 1150 1616 O ATOM 201 CB GLN C 23 61.593 -34.960 -3.721 1.00 41.50 C ANISOU 201 CB GLN C 23 5391 4808 5571 -5 1140 1319 C ATOM 202 CG GLN C 23 61.126 -33.613 -3.248 1.00 57.83 C ANISOU 202 CG GLN C 23 7737 6500 7737 -180 1091 1306 C ATOM 203 CD GLN C 23 62.160 -32.528 -3.487 1.00 59.88 C ANISOU 203 CD GLN C 23 8085 6651 8017 -533 1212 1593 C ATOM 204 OE1 GLN C 23 63.075 -32.690 -4.299 1.00 71.85 O ANISOU 204 OE1 GLN C 23 9444 8404 9453 -587 1381 1836 O ATOM 205 NE2 GLN C 23 62.025 -31.418 -2.773 1.00 64.81 N ANISOU 205 NE2 GLN C 23 8983 6912 8729 -791 1143 1567 N ATOM 206 N GLN C 24 62.599 -34.621 -0.578 1.00 29.08 N ANISOU 206 N GLN C 24 3717 3671 3662 -320 187 481 N ATOM 207 CA GLN C 24 63.190 -33.818 0.478 1.00 29.44 C ANISOU 207 CA GLN C 24 3866 3591 3727 -433 323 382 C ATOM 208 C GLN C 24 64.250 -34.584 1.269 1.00 32.22 C ANISOU 208 C GLN C 24 4097 4212 3934 -528 350 229 C ATOM 209 O GLN C 24 65.152 -33.987 1.864 1.00 35.19 O ANISOU 209 O GLN C 24 4530 4651 4189 -770 412 194 O ATOM 210 CB GLN C 24 62.083 -33.320 1.410 1.00 31.90 C ANISOU 210 CB GLN C 24 4252 3558 4311 -296 440 353 C ATOM 211 CG GLN C 24 61.158 -32.320 0.679 1.00 46.20 C ANISOU 211 CG GLN C 24 6121 5041 6392 -174 427 600 C ATOM 212 CD GLN C 24 59.910 -31.904 1.454 1.00 60.40 C ANISOU 212 CD GLN C 24 7895 6465 8588 54 607 587 C ATOM 213 OE1 GLN C 24 59.071 -31.167 0.929 1.00 70.85 O ANISOU 213 OE1 GLN C 24 9172 7494 10254 230 598 852 O ATOM 214 NE2 GLN C 24 59.786 -32.357 2.693 1.00 59.98 N ANISOU 214 NE2 GLN C 24 7848 6425 8517 34 780 308 N ATOM 215 N ASN C 25 64.111 -35.909 1.289 1.00 28.27 N ANISOU 215 N ASN C 25 3423 3858 3461 -362 290 181 N ATOM 216 CA ASN C 25 65.014 -36.789 2.022 1.00 30.04 C ANISOU 216 CA ASN C 25 3463 4295 3657 -383 274 136 C ATOM 217 C ASN C 25 65.474 -37.959 1.188 1.00 26.80 C ANISOU 217 C ASN C 25 2868 4038 3277 -236 289 110 C ATOM 218 O ASN C 25 65.053 -39.093 1.410 1.00 26.51 O ANISOU 218 O ASN C 25 2759 3960 3352 -60 263 76 O ATOM 219 CB ASN C 25 64.264 -37.379 3.208 1.00 37.49 C ANISOU 219 CB ASN C 25 4404 5151 4689 -315 232 99 C ATOM 220 CG ASN C 25 63.616 -36.319 4.052 1.00 42.51 C ANISOU 220 CG ASN C 25 5247 5578 5327 -461 331 37 C ATOM 221 OD1 ASN C 25 64.236 -35.791 4.980 1.00 40.38 O ANISOU 221 OD1 ASN C 25 5052 5365 4926 -753 379 5 O ATOM 222 ND2 ASN C 25 62.350 -35.987 3.732 1.00 37.19 N ANISOU 222 ND2 ASN C 25 4658 4658 4815 -289 390 26 N ATOM 223 N PRO C 26 66.322 -37.711 0.192 1.00 28.18 N ANISOU 223 N PRO C 26 2992 4363 3351 -336 375 98 N ATOM 224 CA PRO C 26 66.527 -38.829 -0.731 1.00 28.98 C ANISOU 224 CA PRO C 26 2987 4531 3491 -215 499 -12 C ATOM 225 C PRO C 26 67.291 -40.003 -0.112 1.00 32.91 C ANISOU 225 C PRO C 26 3196 5081 4226 -21 562 -20 C ATOM 226 O PRO C 26 67.436 -41.035 -0.783 1.00 32.61 O ANISOU 226 O PRO C 26 3090 4999 4300 118 744 -152 O ATOM 227 CB PRO C 26 67.340 -38.195 -1.872 1.00 30.93 C ANISOU 227 CB PRO C 26 3245 4958 3550 -441 627 -48 C ATOM 228 CG PRO C 26 67.979 -37.007 -1.276 1.00 37.63 C ANISOU 228 CG PRO C 26 4093 5887 4317 -634 555 72 C ATOM 229 CD PRO C 26 67.051 -36.494 -0.211 1.00 29.55 C ANISOU 229 CD PRO C 26 3238 4634 3356 -597 409 148 C ATOM 230 N ASP C 27 67.764 -39.860 1.127 1.00 30.00 N ANISOU 230 N ASP C 27 2671 4789 3938 -47 427 138 N ATOM 231 CA ASP C 27 68.501 -40.962 1.791 1.00 31.80 C ANISOU 231 CA ASP C 27 2561 5070 4450 133 408 266 C ATOM 232 C ASP C 27 67.616 -41.972 2.543 1.00 30.68 C ANISOU 232 C ASP C 27 2485 4719 4452 300 283 303 C ATOM 233 O ASP C 27 68.123 -42.993 3.051 1.00 38.88 O ANISOU 233 O ASP C 27 3265 5730 5778 474 243 461 O ATOM 234 CB ASP C 27 69.517 -40.400 2.775 1.00 34.39 C ANISOU 234 CB ASP C 27 2647 5668 4751 -82 253 515 C ATOM 235 CG ASP C 27 70.548 -39.515 2.110 1.00 38.46 C ANISOU 235 CG ASP C 27 3046 6438 5131 -282 370 509 C ATOM 236 OD1 ASP C 27 71.010 -39.838 0.979 1.00 37.45 O ANISOU 236 OD1 ASP C 27 2794 6340 5094 -153 616 371 O ATOM 237 OD2 ASP C 27 70.928 -38.498 2.738 1.00 40.93 O ANISOU 237 OD2 ASP C 27 3408 6930 5212 -629 245 626 O ATOM 238 N LEU C 28 66.333 -41.668 2.662 1.00 28.18 N ANISOU 238 N LEU C 28 2477 4261 3970 240 212 206 N ATOM 239 CA LEU C 28 65.425 -42.484 3.478 1.00 29.71 C ANISOU 239 CA LEU C 28 2752 4308 4231 311 83 238 C ATOM 240 C LEU C 28 64.674 -43.540 2.644 1.00 33.77 C ANISOU 240 C LEU C 28 3391 4624 4815 492 193 85 C ATOM 241 O LEU C 28 64.107 -43.233 1.610 1.00 34.32 O ANISOU 241 O LEU C 28 3631 4671 4736 449 292 -59 O ATOM 242 CB LEU C 28 64.430 -41.599 4.209 1.00 28.08 C ANISOU 242 CB LEU C 28 2761 4074 3835 120 -5 208 C ATOM 243 CG LEU C 28 65.081 -40.626 5.209 1.00 29.98 C ANISOU 243 CG LEU C 28 2977 4471 3944 -176 -70 307 C ATOM 244 CD1 LEU C 28 63.989 -39.786 5.851 1.00 30.24 C ANISOU 244 CD1 LEU C 28 3267 4378 3844 -346 -20 182 C ATOM 245 CD2 LEU C 28 65.872 -41.378 6.254 1.00 34.78 C ANISOU 245 CD2 LEU C 28 3355 5241 4620 -275 -253 547 C ATOM 246 N HIS C 29 64.703 -44.793 3.092 1.00 30.72 N ANISOU 246 N HIS C 29 2934 4097 4642 640 163 150 N ATOM 247 CA HIS C 29 64.000 -45.868 2.387 1.00 29.97 C ANISOU 247 CA HIS C 29 3022 3780 4585 741 295 -18 C ATOM 248 C HIS C 29 62.484 -45.752 2.558 1.00 28.78 C ANISOU 248 C HIS C 29 3121 3617 4199 599 162 -73 C ATOM 249 O HIS C 29 62.016 -45.080 3.472 1.00 25.39 O ANISOU 249 O HIS C 29 2688 3282 3677 490 -4 19 O ATOM 250 CB HIS C 29 64.445 -47.215 2.951 1.00 34.17 C ANISOU 250 CB HIS C 29 3429 4092 5463 938 295 108 C ATOM 251 CG HIS C 29 65.896 -47.495 2.751 1.00 37.92 C ANISOU 251 CG HIS C 29 3562 4544 6302 1152 463 208 C ATOM 252 ND1 HIS C 29 66.552 -48.538 3.374 1.00 48.15 N ANISOU 252 ND1 HIS C 29 4608 5642 8046 1386 430 460 N ATOM 253 CD2 HIS C 29 66.822 -46.879 1.978 1.00 38.25 C ANISOU 253 CD2 HIS C 29 3429 4740 6364 1170 675 121 C ATOM 254 CE1 HIS C 29 67.819 -48.545 3.004 1.00 46.55 C ANISOU 254 CE1 HIS C 29 4036 5474 8175 1581 630 533 C ATOM 255 NE2 HIS C 29 68.008 -47.547 2.155 1.00 47.59 N ANISOU 255 NE2 HIS C 29 4218 5840 8024 1433 796 301 N ATOM 256 N ASN C 30 61.710 -46.443 1.715 1.00 26.72 N ANISOU 256 N ASN C 30 3066 3247 3840 560 262 -228 N ATOM 257 CA ASN C 30 60.247 -46.327 1.810 1.00 25.18 C ANISOU 257 CA ASN C 30 3026 3105 3434 408 120 -227 C ATOM 258 C ASN C 30 59.684 -46.804 3.126 1.00 27.32 C ANISOU 258 C ASN C 30 3292 3334 3753 394 -53 -126 C ATOM 259 O ASN C 30 58.652 -46.288 3.566 1.00 26.21 O ANISOU 259 O ASN C 30 3166 3302 3492 284 -157 -98 O ATOM 260 CB ASN C 30 59.568 -47.082 0.667 1.00 26.49 C ANISOU 260 CB ASN C 30 3419 3223 3424 261 232 -376 C ATOM 261 CG ASN C 30 59.404 -46.205 -0.560 1.00 26.80 C ANISOU 261 CG ASN C 30 3501 3445 3237 84 271 -395 C ATOM 262 OD1 ASN C 30 58.918 -45.082 -0.451 1.00 25.53 O ANISOU 262 OD1 ASN C 30 3242 3429 3028 57 114 -239 O ATOM 263 ND2 ASN C 30 59.810 -46.707 -1.715 1.00 29.15 N ANISOU 263 ND2 ASN C 30 3955 3712 3407 -64 501 -580 N ATOM 264 N ALA C 31 60.339 -47.783 3.754 1.00 25.97 N ANISOU 264 N ALA C 31 3080 3004 3785 492 -74 -47 N ATOM 265 CA ALA C 31 59.854 -48.216 5.071 1.00 26.94 C ANISOU 265 CA ALA C 31 3214 3123 3900 387 -281 95 C ATOM 266 C ALA C 31 59.839 -47.064 6.050 1.00 26.29 C ANISOU 266 C ALA C 31 3022 3259 3710 241 -392 173 C ATOM 267 O ALA C 31 58.902 -46.932 6.836 1.00 27.40 O ANISOU 267 O ALA C 31 3229 3481 3701 54 -468 159 O ATOM 268 CB ALA C 31 60.719 -49.333 5.637 1.00 29.37 C ANISOU 268 CB ALA C 31 3444 3221 4495 509 -345 285 C ATOM 269 N VAL C 32 60.922 -46.281 6.071 1.00 24.80 N ANISOU 269 N VAL C 32 2674 3161 3587 278 -365 241 N ATOM 270 CA VAL C 32 60.990 -45.129 6.965 1.00 24.62 C ANISOU 270 CA VAL C 32 2618 3313 3422 59 -410 270 C ATOM 271 C VAL C 32 59.985 -44.081 6.521 1.00 22.79 C ANISOU 271 C VAL C 32 2490 3090 3078 37 -269 86 C ATOM 272 O VAL C 32 59.283 -43.490 7.347 1.00 24.99 O ANISOU 272 O VAL C 32 2827 3407 3262 -141 -230 19 O ATOM 273 CB VAL C 32 62.415 -44.502 6.976 1.00 29.76 C ANISOU 273 CB VAL C 32 3088 4085 4134 45 -413 395 C ATOM 274 CG1 VAL C 32 62.501 -43.468 8.057 1.00 31.98 C ANISOU 274 CG1 VAL C 32 3411 4533 4208 -303 -451 416 C ATOM 275 CG2 VAL C 32 63.451 -45.603 7.202 1.00 36.12 C ANISOU 275 CG2 VAL C 32 3674 4860 5191 169 -539 655 C ATOM 276 N LEU C 33 59.904 -43.837 5.216 1.00 22.32 N ANISOU 276 N LEU C 33 2442 2988 3049 195 -174 21 N ATOM 277 CA LEU C 33 58.925 -42.862 4.737 1.00 21.78 C ANISOU 277 CA LEU C 33 2411 2915 2948 196 -97 -35 C ATOM 278 C LEU C 33 57.511 -43.265 5.184 1.00 21.72 C ANISOU 278 C LEU C 33 2424 2909 2918 147 -125 -62 C ATOM 279 O LEU C 33 56.699 -42.410 5.521 1.00 22.08 O ANISOU 279 O LEU C 33 2428 2939 3021 128 -32 -90 O ATOM 280 CB LEU C 33 58.978 -42.708 3.210 1.00 23.07 C ANISOU 280 CB LEU C 33 2591 3085 3090 277 -65 -23 C ATOM 281 CG LEU C 33 60.306 -42.188 2.663 1.00 23.95 C ANISOU 281 CG LEU C 33 2667 3231 3202 288 5 -19 C ATOM 282 CD1 LEU C 33 60.251 -42.103 1.128 1.00 24.15 C ANISOU 282 CD1 LEU C 33 2751 3300 3126 257 47 -24 C ATOM 283 CD2 LEU C 33 60.602 -40.794 3.256 1.00 28.64 C ANISOU 283 CD2 LEU C 33 3256 3816 3811 209 46 11 C ATOM 284 N SER C 34 57.215 -44.563 5.163 1.00 21.32 N ANISOU 284 N SER C 34 2697 2533 2869 -91 -152 29 N ATOM 285 CA SER C 34 55.890 -45.008 5.564 1.00 22.54 C ANISOU 285 CA SER C 34 2936 2584 3043 -162 -74 38 C ATOM 286 C SER C 34 55.613 -44.690 7.011 1.00 24.04 C ANISOU 286 C SER C 34 3243 2807 3084 -186 -53 170 C ATOM 287 O SER C 34 54.495 -44.315 7.388 1.00 23.39 O ANISOU 287 O SER C 34 3192 2744 2950 -250 52 173 O ATOM 288 CB SER C 34 55.739 -46.516 5.356 1.00 24.64 C ANISOU 288 CB SER C 34 3198 2646 3520 -124 -66 38 C ATOM 289 OG SER C 34 55.773 -46.822 3.954 1.00 23.47 O ANISOU 289 OG SER C 34 2945 2507 3466 -37 -116 -182 O ATOM 290 N LYS C 35 56.625 -44.870 7.856 1.00 22.27 N ANISOU 290 N LYS C 35 3077 2624 2760 -81 -161 261 N ATOM 291 CA LYS C 35 56.439 -44.524 9.269 1.00 22.64 C ANISOU 291 CA LYS C 35 3262 2787 2554 4 -178 351 C ATOM 292 C LYS C 35 56.155 -43.032 9.409 1.00 22.64 C ANISOU 292 C LYS C 35 3229 2917 2456 -37 -244 169 C ATOM 293 O LYS C 35 55.306 -42.626 10.215 1.00 25.19 O ANISOU 293 O LYS C 35 3646 3341 2584 7 -172 174 O ATOM 294 CB LYS C 35 57.684 -44.918 10.070 1.00 24.04 C ANISOU 294 CB LYS C 35 3495 3024 2614 197 -366 415 C ATOM 295 CG LYS C 35 57.855 -46.418 10.192 1.00 26.15 C ANISOU 295 CG LYS C 35 3840 3128 2966 286 -295 648 C ATOM 296 CD LYS C 35 59.247 -46.772 10.774 1.00 27.72 C ANISOU 296 CD LYS C 35 4063 3396 3075 516 -537 671 C ATOM 297 CE LYS C 35 59.351 -48.238 11.165 1.00 31.78 C ANISOU 297 CE LYS C 35 4709 3729 3637 667 -468 969 C ATOM 298 NZ LYS C 35 60.684 -48.544 11.820 1.00 35.16 N ANISOU 298 NZ LYS C 35 5170 4259 3930 955 -742 985 N ATOM 299 N MET C 36 56.882 -42.216 8.648 1.00 21.75 N ANISOU 299 N MET C 36 2969 2791 2505 -98 -361 28 N ATOM 300 CA MET C 36 56.670 -40.763 8.663 1.00 22.43 C ANISOU 300 CA MET C 36 2996 2901 2627 -151 -434 -132 C ATOM 301 C MET C 36 55.275 -40.371 8.154 1.00 20.84 C ANISOU 301 C MET C 36 2821 2685 2412 -232 -266 -149 C ATOM 302 O MET C 36 54.609 -39.489 8.750 1.00 24.02 O ANISOU 302 O MET C 36 3266 3139 2722 -207 -293 -263 O ATOM 303 CB MET C 36 57.759 -40.067 7.829 1.00 20.99 C ANISOU 303 CB MET C 36 2603 2638 2733 -220 -518 -175 C ATOM 304 CG MET C 36 59.105 -40.299 8.479 1.00 25.22 C ANISOU 304 CG MET C 36 3048 3194 3340 -132 -734 -229 C ATOM 305 SD MET C 36 60.478 -39.944 7.335 1.00 27.61 S ANISOU 305 SD MET C 36 3020 3404 4065 -221 -712 -178 S ATOM 306 CE MET C 36 60.397 -38.168 7.200 1.00 27.57 C ANISOU 306 CE MET C 36 2847 3234 4394 -362 -760 -271 C ATOM 307 N LEU C 37 54.846 -41.039 7.076 1.00 22.45 N ANISOU 307 N LEU C 37 2985 2834 2710 -286 -131 -88 N ATOM 308 CA LEU C 37 53.529 -40.796 6.482 1.00 22.71 C ANISOU 308 CA LEU C 37 3004 2863 2760 -328 -20 -147 C ATOM 309 C LEU C 37 52.401 -41.177 7.440 1.00 21.48 C ANISOU 309 C LEU C 37 2909 2738 2513 -334 98 -123 C ATOM 310 O LEU C 37 51.398 -40.450 7.545 1.00 22.34 O ANISOU 310 O LEU C 37 3000 2897 2591 -339 148 -215 O ATOM 311 CB LEU C 37 53.387 -41.577 5.172 1.00 21.56 C ANISOU 311 CB LEU C 37 2789 2679 2723 -314 24 -168 C ATOM 312 CG LEU C 37 54.261 -41.053 4.060 1.00 22.83 C ANISOU 312 CG LEU C 37 2882 2888 2906 -248 -2 -147 C ATOM 313 CD1 LEU C 37 54.437 -42.133 2.954 1.00 20.63 C ANISOU 313 CD1 LEU C 37 2558 2634 2645 -134 10 -203 C ATOM 314 CD2 LEU C 37 53.652 -39.768 3.466 1.00 27.64 C ANISOU 314 CD2 LEU C 37 3477 3531 3495 -224 20 -163 C ATOM 315 N GLY C 38 52.544 -42.302 8.159 1.00 21.77 N ANISOU 315 N GLY C 38 3006 2744 2520 -311 175 35 N ATOM 316 CA GLY C 38 51.534 -42.686 9.142 1.00 24.78 C ANISOU 316 CA GLY C 38 3428 3165 2821 -294 376 167 C ATOM 317 C GLY C 38 51.345 -41.604 10.195 1.00 26.47 C ANISOU 317 C GLY C 38 3733 3592 2731 -165 353 98 C ATOM 318 O GLY C 38 50.205 -41.241 10.567 1.00 26.78 O ANISOU 318 O GLY C 38 3740 3725 2711 -150 515 74 O ATOM 319 N LYS C 39 52.462 -41.074 10.704 1.00 25.02 N ANISOU 319 N LYS C 39 3635 3494 2377 -44 129 16 N ATOM 320 CA LYS C 39 52.370 -40.058 11.752 1.00 29.51 C ANISOU 320 CA LYS C 39 4286 4262 2664 139 23 -151 C ATOM 321 C LYS C 39 51.778 -38.750 11.243 1.00 26.38 C ANISOU 321 C LYS C 39 3799 3826 2398 76 -48 -405 C ATOM 322 O LYS C 39 50.950 -38.111 11.946 1.00 29.65 O ANISOU 322 O LYS C 39 4249 4394 2623 209 2 -531 O ATOM 323 CB LYS C 39 53.742 -39.827 12.427 1.00 32.30 C ANISOU 323 CB LYS C 39 4703 4688 2881 307 -284 -265 C ATOM 324 CG LYS C 39 54.009 -40.902 13.437 1.00 41.86 C ANISOU 324 CG LYS C 39 6078 6053 3774 525 -209 -17 C ATOM 325 CD LYS C 39 55.327 -40.743 14.155 1.00 49.72 C ANISOU 325 CD LYS C 39 7126 7162 4602 757 -566 -172 C ATOM 326 CE LYS C 39 55.535 -41.945 15.074 1.00 53.86 C ANISOU 326 CE LYS C 39 7848 7840 4775 1022 -460 163 C ATOM 327 NZ LYS C 39 54.353 -42.208 15.965 1.00 59.36 N ANISOU 327 NZ LYS C 39 8710 8763 5082 1213 -113 417 N ATOM 328 N ALA C 40 52.182 -38.365 10.032 1.00 24.00 N ANISOU 328 N ALA C 40 3384 3335 2398 -83 -141 -455 N ATOM 329 CA ALA C 40 51.694 -37.142 9.416 1.00 24.48 C ANISOU 329 CA ALA C 40 3371 3309 2623 -123 -201 -619 C ATOM 330 C ALA C 40 50.205 -37.235 9.104 1.00 24.88 C ANISOU 330 C ALA C 40 3384 3409 2659 -140 -2 -617 C ATOM 331 O ALA C 40 49.484 -36.245 9.264 1.00 27.12 O ANISOU 331 O ALA C 40 3650 3715 2938 -69 -34 -785 O ATOM 332 CB ALA C 40 52.466 -36.833 8.156 1.00 21.98 C ANISOU 332 CB ALA C 40 2952 2812 2587 -238 -265 -557 C ATOM 333 N TRP C 41 49.746 -38.404 8.653 1.00 24.09 N ANISOU 333 N TRP C 41 3237 3298 2618 -224 172 -466 N ATOM 334 CA TRP C 41 48.307 -38.576 8.378 1.00 25.38 C ANISOU 334 CA TRP C 41 3286 3489 2867 -251 337 -506 C ATOM 335 C TRP C 41 47.527 -38.429 9.658 1.00 29.67 C ANISOU 335 C TRP C 41 3848 4209 3215 -144 504 -503 C ATOM 336 O TRP C 41 46.508 -37.714 9.723 1.00 26.80 O ANISOU 336 O TRP C 41 3403 3923 2858 -82 554 -653 O ATOM 337 CB TRP C 41 48.045 -39.952 7.755 1.00 26.95 C ANISOU 337 CB TRP C 41 3383 3582 3276 -365 448 -397 C ATOM 338 CG TRP C 41 46.577 -40.322 7.608 1.00 22.53 C ANISOU 338 CG TRP C 41 2623 3011 2925 -418 609 -458 C ATOM 339 CD1 TRP C 41 45.868 -41.204 8.378 1.00 26.37 C ANISOU 339 CD1 TRP C 41 3002 3480 3536 -480 876 -293 C ATOM 340 CD2 TRP C 41 45.667 -39.830 6.609 1.00 25.73 C ANISOU 340 CD2 TRP C 41 2876 3411 3491 -399 513 -687 C ATOM 341 NE1 TRP C 41 44.553 -41.291 7.920 1.00 27.08 N ANISOU 341 NE1 TRP C 41 2824 3529 3934 -543 954 -439 N ATOM 342 CE2 TRP C 41 44.417 -40.463 6.830 1.00 24.61 C ANISOU 342 CE2 TRP C 41 2490 3240 3618 -474 696 -715 C ATOM 343 CE3 TRP C 41 45.785 -38.896 5.570 1.00 25.75 C ANISOU 343 CE3 TRP C 41 2913 3432 3441 -297 304 -839 C ATOM 344 CZ2 TRP C 41 43.293 -40.200 6.029 1.00 29.35 C ANISOU 344 CZ2 TRP C 41 2861 3844 4446 -446 608 -974 C ATOM 345 CZ3 TRP C 41 44.672 -38.645 4.763 1.00 25.96 C ANISOU 345 CZ3 TRP C 41 2772 3485 3608 -225 227 -1049 C ATOM 346 CH2 TRP C 41 43.438 -39.298 5.005 1.00 25.06 C ANISOU 346 CH2 TRP C 41 2397 3357 3769 -297 347 -1156 C ATOM 347 N LYS C 42 47.987 -39.085 10.713 1.00 28.40 N ANISOU 347 N LYS C 42 3799 4151 2840 -66 605 -323 N ATOM 348 CA LYS C 42 47.303 -38.920 11.998 1.00 32.47 C ANISOU 348 CA LYS C 42 4361 4921 3055 128 806 -282 C ATOM 349 C LYS C 42 47.293 -37.487 12.542 1.00 33.86 C ANISOU 349 C LYS C 42 4609 5252 3004 340 607 -605 C ATOM 350 O LYS C 42 46.366 -37.100 13.249 1.00 38.34 O ANISOU 350 O LYS C 42 5149 6037 3380 513 774 -676 O ATOM 351 CB LYS C 42 47.834 -39.934 13.030 1.00 36.98 C ANISOU 351 CB LYS C 42 5077 5608 3365 254 964 36 C ATOM 352 CG LYS C 42 47.565 -41.363 12.607 1.00 37.92 C ANISOU 352 CG LYS C 42 5086 5511 3810 53 1212 363 C ATOM 353 CD LYS C 42 47.902 -42.412 13.678 1.00 48.28 C ANISOU 353 CD LYS C 42 6542 6903 4901 204 1447 785 C ATOM 354 CE LYS C 42 47.385 -43.798 13.246 1.00 47.57 C ANISOU 354 CE LYS C 42 6275 6495 5305 -28 1731 1110 C ATOM 355 NZ LYS C 42 47.987 -44.939 14.002 1.00 57.06 N ANISOU 355 NZ LYS C 42 7631 7636 6412 89 1899 1565 N ATOM 356 N GLU C 43 48.318 -36.702 12.222 1.00 33.58 N ANISOU 356 N GLU C 43 3934 5966 2860 -286 -509 -440 N ATOM 357 CA GLU C 43 48.358 -35.296 12.636 1.00 33.09 C ANISOU 357 CA GLU C 43 3741 5835 2999 -410 -685 -885 C ATOM 358 C GLU C 43 47.357 -34.397 11.890 1.00 31.43 C ANISOU 358 C GLU C 43 3544 5256 3143 -492 -527 -1036 C ATOM 359 O GLU C 43 47.029 -33.319 12.384 1.00 38.72 O ANISOU 359 O GLU C 43 4439 6118 4155 -561 -598 -1425 O ATOM 360 CB GLU C 43 49.770 -34.705 12.492 1.00 35.06 C ANISOU 360 CB GLU C 43 3721 6059 3543 -511 -955 -934 C ATOM 361 CG GLU C 43 50.729 -35.180 13.555 1.00 62.72 C ANISOU 361 CG GLU C 43 7159 9988 6684 -437 -1207 -966 C ATOM 362 CD GLU C 43 51.661 -34.082 14.059 1.00 70.16 C ANISOU 362 CD GLU C 43 7832 10955 7871 -587 -1571 -1353 C ATOM 363 OE1 GLU C 43 52.169 -33.297 13.228 1.00 75.38 O ANISOU 363 OE1 GLU C 43 8263 11277 9103 -752 -1608 -1349 O ATOM 364 OE2 GLU C 43 51.885 -34.009 15.291 1.00 65.14 O ANISOU 364 OE2 GLU C 43 7212 10673 6866 -522 -1819 -1662 O ATOM 365 N LEU C 44 46.920 -34.798 10.698 1.00 28.15 N ANISOU 365 N LEU C 44 3175 4599 2923 -458 -331 -748 N ATOM 366 CA LEU C 44 45.984 -33.964 9.931 1.00 26.78 C ANISOU 366 CA LEU C 44 3002 4110 3064 -487 -185 -865 C ATOM 367 C LEU C 44 44.656 -33.846 10.665 1.00 31.95 C ANISOU 367 C LEU C 44 3785 4859 3494 -467 -61 -1090 C ATOM 368 O LEU C 44 44.185 -34.832 11.237 1.00 29.81 O ANISOU 368 O LEU C 44 3637 4810 2878 -398 28 -970 O ATOM 369 CB LEU C 44 45.723 -34.574 8.550 1.00 23.56 C ANISOU 369 CB LEU C 44 2645 3489 2817 -394 -30 -519 C ATOM 370 CG LEU C 44 46.909 -34.623 7.591 1.00 30.82 C ANISOU 370 CG LEU C 44 3456 4265 3991 -345 -78 -237 C ATOM 371 CD1 LEU C 44 46.388 -35.203 6.280 1.00 26.21 C ANISOU 371 CD1 LEU C 44 2992 3487 3479 -189 78 37 C ATOM 372 CD2 LEU C 44 47.512 -33.252 7.371 1.00 32.08 C ANISOU 372 CD2 LEU C 44 3405 4207 4575 -431 -140 -400 C ATOM 373 N ASN C 45 44.054 -32.654 10.669 1.00 28.30 N ANISOU 373 N ASN C 45 3292 4222 3239 -507 -22 -1387 N ATOM 374 CA ASN C 45 42.730 -32.505 11.272 1.00 28.97 C ANISOU 374 CA ASN C 45 3487 4385 3134 -453 136 -1560 C ATOM 375 C ASN C 45 41.655 -33.032 10.316 1.00 26.20 C ANISOU 375 C ASN C 45 3163 3899 2892 -401 349 -1327 C ATOM 376 O ASN C 45 41.947 -33.370 9.175 1.00 26.03 O ANISOU 376 O ASN C 45 3105 3707 3078 -386 350 -1089 O ATOM 377 CB ASN C 45 42.476 -31.049 11.726 1.00 31.47 C ANISOU 377 CB ASN C 45 3786 4577 3595 -485 104 -1979 C ATOM 378 CG ASN C 45 42.483 -30.049 10.578 1.00 34.98 C ANISOU 378 CG ASN C 45 4122 4631 4537 -525 163 -1995 C ATOM 379 OD1 ASN C 45 41.993 -30.336 9.484 1.00 32.92 O ANISOU 379 OD1 ASN C 45 3846 4222 4441 -463 311 -1743 O ATOM 380 ND2 ASN C 45 43.042 -28.861 10.829 1.00 36.98 N ANISOU 380 ND2 ASN C 45 4303 4707 5040 -611 46 -2300 N ATOM 381 N THR C 46 40.417 -33.122 10.801 1.00 26.79 N ANISOU 381 N THR C 46 3295 4064 2819 -351 519 -1397 N ATOM 382 CA THR C 46 39.354 -33.670 9.972 1.00 26.48 C ANISOU 382 CA THR C 46 3236 3921 2903 -320 679 -1206 C ATOM 383 C THR C 46 39.195 -32.937 8.652 1.00 24.34 C ANISOU 383 C THR C 46 2888 3360 3001 -290 683 -1205 C ATOM 384 O THR C 46 39.017 -33.572 7.603 1.00 26.02 O ANISOU 384 O THR C 46 3091 3466 3332 -248 688 -990 O ATOM 385 CB THR C 46 38.065 -33.665 10.737 1.00 32.15 C ANISOU 385 CB THR C 46 3968 4771 3475 -274 872 -1292 C ATOM 386 OG1 THR C 46 38.260 -34.468 11.897 1.00 31.84 O ANISOU 386 OG1 THR C 46 4017 5007 3072 -245 906 -1221 O ATOM 387 CG2 THR C 46 36.913 -34.265 9.903 1.00 31.85 C ANISOU 387 CG2 THR C 46 3853 4633 3617 -269 1007 -1112 C ATOM 388 N ALA C 47 39.284 -31.609 8.708 1.00 28.86 N ANISOU 388 N ALA C 47 3422 3798 3746 -284 683 -1449 N ATOM 389 CA ALA C 47 39.087 -30.809 7.496 1.00 30.71 C ANISOU 389 CA ALA C 47 3587 3754 4327 -203 742 -1427 C ATOM 390 C ALA C 47 40.178 -31.077 6.488 1.00 31.25 C ANISOU 390 C ALA C 47 3627 3677 4570 -176 647 -1191 C ATOM 391 O ALA C 47 39.943 -31.018 5.266 1.00 28.33 O ANISOU 391 O ALA C 47 3237 3141 4385 -36 706 -1031 O ATOM 392 CB ALA C 47 39.068 -29.336 7.840 1.00 30.11 C ANISOU 392 CB ALA C 47 3489 3523 4427 -204 788 -1724 C ATOM 393 N GLU C 48 41.387 -31.348 6.986 1.00 23.72 N ANISOU 393 N GLU C 48 2667 2802 3544 -272 504 -1157 N ATOM 394 CA GLU C 48 42.517 -31.588 6.082 1.00 24.72 C ANISOU 394 CA GLU C 48 2746 2801 3844 -226 439 -894 C ATOM 395 C GLU C 48 42.423 -32.964 5.425 1.00 26.26 C ANISOU 395 C GLU C 48 3037 3071 3868 -131 437 -588 C ATOM 396 O GLU C 48 42.837 -33.151 4.266 1.00 24.11 O ANISOU 396 O GLU C 48 2775 2648 3737 16 454 -348 O ATOM 397 CB GLU C 48 43.852 -31.438 6.821 1.00 27.33 C ANISOU 397 CB GLU C 48 2994 3209 4181 -356 272 -949 C ATOM 398 CG GLU C 48 44.131 -29.980 7.207 1.00 28.59 C ANISOU 398 CG GLU C 48 3038 3188 4636 -456 242 -1260 C ATOM 399 CD GLU C 48 45.305 -29.825 8.151 1.00 41.37 C ANISOU 399 CD GLU C 48 4554 4926 6239 -612 10 -1418 C ATOM 400 OE1 GLU C 48 45.474 -30.683 9.050 1.00 35.49 O ANISOU 400 OE1 GLU C 48 3878 4508 5098 -634 -115 -1433 O ATOM 401 OE2 GLU C 48 46.060 -28.842 7.994 1.00 45.47 O ANISOU 401 OE2 GLU C 48 4908 5210 7161 -704 -47 -1523 O ATOM 402 N LYS C 49 41.883 -33.919 6.170 1.00 25.60 N ANISOU 402 N LYS C 49 2436 3957 3335 -17 924 -61 N ATOM 403 CA LYS C 49 41.691 -35.273 5.657 1.00 25.65 C ANISOU 403 CA LYS C 49 2436 3963 3346 -39 892 -17 C ATOM 404 C LYS C 49 40.527 -35.353 4.692 1.00 25.62 C ANISOU 404 C LYS C 49 2346 3924 3466 44 720 -115 C ATOM 405 O LYS C 49 40.534 -36.222 3.801 1.00 25.53 O ANISOU 405 O LYS C 49 2416 3880 3406 35 644 -54 O ATOM 406 CB LYS C 49 41.418 -36.242 6.805 1.00 24.56 C ANISOU 406 CB LYS C 49 2298 3787 3248 -77 899 46 C ATOM 407 CG LYS C 49 42.675 -36.635 7.588 1.00 26.14 C ANISOU 407 CG LYS C 49 2689 3876 3368 -86 902 124 C ATOM 408 CD LYS C 49 42.302 -37.690 8.610 1.00 28.41 C ANISOU 408 CD LYS C 49 2959 4207 3629 -165 928 160 C ATOM 409 CE LYS C 49 43.530 -38.153 9.405 1.00 33.74 C ANISOU 409 CE LYS C 49 3768 4837 4214 -173 942 189 C ATOM 410 NZ LYS C 49 43.431 -37.784 10.854 1.00 43.34 N ANISOU 410 NZ LYS C 49 4962 6121 5385 -246 981 204 N ATOM 411 N ARG C 50 39.567 -34.450 4.856 1.00 21.73 N ANISOU 411 N ARG C 50 1729 3375 3151 161 596 -278 N ATOM 412 CA ARG C 50 38.265 -34.543 4.172 1.00 23.24 C ANISOU 412 CA ARG C 50 1791 3505 3533 297 355 -442 C ATOM 413 C ARG C 50 38.372 -34.795 2.641 1.00 22.41 C ANISOU 413 C ARG C 50 1958 3232 3324 351 117 -312 C ATOM 414 O ARG C 50 37.668 -35.692 2.112 1.00 23.68 O ANISOU 414 O ARG C 50 2012 3431 3554 351 40 -366 O ATOM 415 CB ARG C 50 37.371 -33.340 4.489 1.00 24.90 C ANISOU 415 CB ARG C 50 1842 3651 3969 496 174 -700 C ATOM 416 CG ARG C 50 36.040 -33.377 3.788 1.00 26.71 C ANISOU 416 CG ARG C 50 1888 3836 4424 694 -136 -944 C ATOM 417 CD ARG C 50 35.168 -32.215 4.227 1.00 29.42 C ANISOU 417 CD ARG C 50 2007 4133 5037 949 -347 -1295 C ATOM 418 NE ARG C 50 33.881 -32.163 3.523 1.00 37.68 N ANISOU 418 NE ARG C 50 2897 5127 6293 1173 -711 -1576 N ATOM 419 CZ ARG C 50 32.967 -31.215 3.707 1.00 47.68 C ANISOU 419 CZ ARG C 50 4086 6306 7725 1368 -959 -1883 C ATOM 420 NH1 ARG C 50 33.200 -30.224 4.559 1.00 49.03 N ANISOU 420 NH1 ARG C 50 4263 6434 7934 1410 -906 -1970 N ATOM 421 NH2 ARG C 50 31.821 -31.251 3.030 1.00 52.33 N ANISOU 421 NH2 ARG C 50 4586 6854 8442 1524 -1273 -2136 N ATOM 422 N PRO C 51 39.218 -34.032 1.923 1.00 21.39 N ANISOU 422 N PRO C 51 2198 2931 3000 343 15 -162 N ATOM 423 CA PRO C 51 39.212 -34.287 0.468 1.00 24.13 C ANISOU 423 CA PRO C 51 2823 3133 3213 332 -206 -68 C ATOM 424 C PRO C 51 39.685 -35.685 0.107 1.00 25.19 C ANISOU 424 C PRO C 51 2914 3414 3246 190 -29 10 C ATOM 425 O PRO C 51 39.290 -36.258 -0.918 1.00 23.18 O ANISOU 425 O PRO C 51 2740 3103 2964 191 -184 22 O ATOM 426 CB PRO C 51 40.216 -33.262 -0.078 1.00 23.89 C ANISOU 426 CB PRO C 51 3240 2934 2903 211 -255 68 C ATOM 427 CG PRO C 51 40.262 -32.174 0.949 1.00 28.67 C ANISOU 427 CG PRO C 51 3802 3497 3593 281 -216 4 C ATOM 428 CD PRO C 51 40.018 -32.827 2.267 1.00 23.50 C ANISOU 428 CD PRO C 51 2683 3104 3142 308 53 -105 C ATOM 429 N PHE C 52 40.563 -36.246 0.925 1.00 22.49 N ANISOU 429 N PHE C 52 2466 3239 2841 83 260 50 N ATOM 430 CA PHE C 52 41.092 -37.566 0.622 1.00 23.89 C ANISOU 430 CA PHE C 52 2631 3510 2937 1 371 88 C ATOM 431 C PHE C 52 40.113 -38.638 1.037 1.00 24.03 C ANISOU 431 C PHE C 52 2433 3574 3122 14 377 28 C ATOM 432 O PHE C 52 39.973 -39.659 0.359 1.00 22.73 O ANISOU 432 O PHE C 52 2305 3397 2936 -17 333 36 O ATOM 433 CB PHE C 52 42.444 -37.723 1.319 1.00 21.97 C ANISOU 433 CB PHE C 52 2384 3398 2568 -71 592 110 C ATOM 434 CG PHE C 52 43.384 -36.678 0.900 1.00 21.87 C ANISOU 434 CG PHE C 52 2565 3385 2360 -164 630 118 C ATOM 435 CD1 PHE C 52 44.016 -36.773 -0.314 1.00 20.81 C ANISOU 435 CD1 PHE C 52 2629 3255 2021 -294 612 99 C ATOM 436 CD2 PHE C 52 43.532 -35.517 1.651 1.00 24.46 C ANISOU 436 CD2 PHE C 52 2912 3698 2684 -174 681 123 C ATOM 437 CE1 PHE C 52 44.860 -35.788 -0.803 1.00 23.73 C ANISOU 437 CE1 PHE C 52 3242 3635 2139 -493 671 82 C ATOM 438 CE2 PHE C 52 44.377 -34.518 1.159 1.00 20.53 C ANISOU 438 CE2 PHE C 52 2671 3175 1956 -333 714 129 C ATOM 439 CZ PHE C 52 45.019 -34.643 -0.049 1.00 22.40 C ANISOU 439 CZ PHE C 52 3130 3429 1952 -517 715 110 C ATOM 440 N VAL C 53 39.414 -38.402 2.135 1.00 20.69 N ANISOU 440 N VAL C 53 1799 3218 2844 15 446 -60 N ATOM 441 CA VAL C 53 38.340 -39.309 2.510 1.00 24.14 C ANISOU 441 CA VAL C 53 2042 3729 3402 -68 476 -171 C ATOM 442 C VAL C 53 37.260 -39.313 1.429 1.00 26.01 C ANISOU 442 C VAL C 53 2212 3917 3755 19 244 -285 C ATOM 443 O VAL C 53 36.740 -40.383 1.045 1.00 25.81 O ANISOU 443 O VAL C 53 2151 3916 3739 -72 232 -319 O ATOM 444 CB VAL C 53 37.747 -38.880 3.859 1.00 26.17 C ANISOU 444 CB VAL C 53 2060 4116 3766 -146 621 -320 C ATOM 445 CG1 VAL C 53 36.455 -39.635 4.169 1.00 27.61 C ANISOU 445 CG1 VAL C 53 2009 4426 4056 -311 672 -528 C ATOM 446 CG2 VAL C 53 38.814 -39.101 4.933 1.00 25.93 C ANISOU 446 CG2 VAL C 53 2155 4115 3585 -256 814 -180 C ATOM 447 N GLU C 54 36.905 -38.123 0.951 1.00 23.04 N ANISOU 447 N GLU C 54 1850 3447 3459 198 23 -354 N ATOM 448 CA GLU C 54 35.865 -38.032 -0.058 1.00 24.17 C ANISOU 448 CA GLU C 54 1946 3520 3718 330 -282 -486 C ATOM 449 C GLU C 54 36.299 -38.671 -1.367 1.00 23.73 C ANISOU 449 C GLU C 54 2171 3358 3485 282 -388 -321 C ATOM 450 O GLU C 54 35.490 -39.313 -2.055 1.00 25.98 O ANISOU 450 O GLU C 54 2378 3658 3834 287 -528 -411 O ATOM 451 CB GLU C 54 35.416 -36.580 -0.260 1.00 31.91 C ANISOU 451 CB GLU C 54 2961 4349 4816 577 -591 -603 C ATOM 452 CG GLU C 54 34.558 -36.114 0.918 1.00 35.38 C ANISOU 452 CG GLU C 54 2983 4948 5513 654 -528 -916 C ATOM 453 CD GLU C 54 34.222 -34.636 0.884 1.00 46.93 C ANISOU 453 CD GLU C 54 4487 6227 7118 947 -851 -1067 C ATOM 454 OE1 GLU C 54 34.740 -33.928 -0.010 1.00 52.49 O ANISOU 454 OE1 GLU C 54 5639 6638 7668 1048 -1124 -868 O ATOM 455 OE2 GLU C 54 33.447 -34.197 1.767 1.00 43.61 O ANISOU 455 OE2 GLU C 54 3678 5950 6944 1048 -833 -1408 O ATOM 456 N GLU C 55 37.560 -38.473 -1.730 1.00 22.31 N ANISOU 456 N GLU C 55 2295 3103 3078 212 -310 -126 N ATOM 457 CA GLU C 55 38.028 -39.057 -2.990 1.00 25.01 C ANISOU 457 CA GLU C 55 2887 3385 3230 122 -375 -28 C ATOM 458 C GLU C 55 38.106 -40.569 -2.886 1.00 25.37 C ANISOU 458 C GLU C 55 2812 3540 3288 21 -200 -39 C ATOM 459 O GLU C 55 37.729 -41.266 -3.831 1.00 24.84 O ANISOU 459 O GLU C 55 2801 3445 3193 -13 -309 -57 O ATOM 460 CB GLU C 55 39.398 -38.511 -3.388 1.00 23.78 C ANISOU 460 CB GLU C 55 3039 3191 2804 2 -282 93 C ATOM 461 CG GLU C 55 39.910 -39.116 -4.724 1.00 24.20 C ANISOU 461 CG GLU C 55 3328 3233 2635 -150 -308 125 C ATOM 462 CD GLU C 55 38.926 -38.948 -5.889 1.00 33.57 C ANISOU 462 CD GLU C 55 4692 4262 3801 -116 -651 127 C ATOM 463 OE1 GLU C 55 38.207 -37.925 -5.976 1.00 33.61 O ANISOU 463 OE1 GLU C 55 4808 4097 3864 16 -944 127 O ATOM 464 OE2 GLU C 55 38.881 -39.849 -6.769 1.00 34.10 O ANISOU 464 OE2 GLU C 55 4808 4359 3790 -206 -667 110 O ATOM 465 N ALA C 56 38.547 -41.101 -1.745 1.00 22.77 N ANISOU 465 N ALA C 56 2362 3303 2988 -32 34 -29 N ATOM 466 CA ALA C 56 38.533 -42.571 -1.586 1.00 23.97 C ANISOU 466 CA ALA C 56 2490 3479 3138 -126 131 -36 C ATOM 467 C ALA C 56 37.137 -43.178 -1.718 1.00 24.78 C ANISOU 467 C ALA C 56 2437 3607 3371 -191 54 -152 C ATOM 468 O ALA C 56 36.972 -44.244 -2.324 1.00 25.40 O ANISOU 468 O ALA C 56 2587 3650 3413 -267 28 -159 O ATOM 469 CB ALA C 56 39.139 -42.990 -0.254 1.00 25.29 C ANISOU 469 CB ALA C 56 2637 3683 3288 -178 317 2 C ATOM 470 N GLU C 57 36.134 -42.501 -1.170 1.00 22.52 N ANISOU 470 N GLU C 57 1914 3403 3241 -169 21 -293 N ATOM 471 CA GLU C 57 34.752 -42.966 -1.312 1.00 26.15 C ANISOU 471 CA GLU C 57 2142 3958 3836 -246 -47 -502 C ATOM 472 C GLU C 57 34.318 -42.898 -2.782 1.00 29.60 C ANISOU 472 C GLU C 57 2643 4321 4282 -127 -331 -530 C ATOM 473 O GLU C 57 33.652 -43.807 -3.283 1.00 26.90 O ANISOU 473 O GLU C 57 2245 4020 3957 -234 -366 -620 O ATOM 474 CB GLU C 57 33.835 -42.156 -0.378 1.00 28.30 C ANISOU 474 CB GLU C 57 2071 4387 4294 -228 -19 -750 C ATOM 475 CG GLU C 57 32.339 -42.448 -0.483 1.00 32.01 C ANISOU 475 CG GLU C 57 2186 5040 4936 -304 -89 -1095 C ATOM 476 CD GLU C 57 31.966 -43.897 -0.182 1.00 33.57 C ANISOU 476 CD GLU C 57 2389 5334 5034 -671 132 -1137 C ATOM 477 OE1 GLU C 57 32.789 -44.650 0.406 1.00 36.35 O ANISOU 477 OE1 GLU C 57 3020 5590 5200 -861 331 -913 O ATOM 478 OE2 GLU C 57 30.830 -44.286 -0.542 1.00 38.78 O ANISOU 478 OE2 GLU C 57 2793 6149 5793 -772 73 -1417 O ATOM 479 N ARG C 58 34.690 -41.839 -3.492 1.00 25.76 N ANISOU 479 N ARG C 58 2328 3709 3750 56 -545 -450 N ATOM 480 CA ARG C 58 34.377 -41.783 -4.932 1.00 27.17 C ANISOU 480 CA ARG C 58 2679 3780 3866 126 -846 -440 C ATOM 481 C ARG C 58 35.019 -42.959 -5.669 1.00 27.37 C ANISOU 481 C ARG C 58 2903 3784 3712 -39 -729 -321 C ATOM 482 O ARG C 58 34.391 -43.549 -6.558 1.00 29.16 O ANISOU 482 O ARG C 58 3135 4008 3936 -74 -876 -386 O ATOM 483 CB ARG C 58 34.838 -40.461 -5.573 1.00 28.15 C ANISOU 483 CB ARG C 58 3112 3713 3870 262 -1098 -329 C ATOM 484 CG ARG C 58 33.859 -39.317 -5.493 1.00 39.62 C ANISOU 484 CG ARG C 58 4455 5085 5514 515 -1450 -502 C ATOM 485 CD ARG C 58 34.528 -38.053 -6.045 1.00 47.49 C ANISOU 485 CD ARG C 58 5915 5816 6313 582 -1687 -330 C ATOM 486 NE ARG C 58 34.104 -36.874 -5.301 1.00 60.87 N ANISOU 486 NE ARG C 58 7505 7428 8196 817 -1862 -465 N ATOM 487 CZ ARG C 58 34.902 -36.126 -4.551 1.00 55.47 C ANISOU 487 CZ ARG C 58 6930 6701 7447 785 -1687 -368 C ATOM 488 NH1 ARG C 58 36.203 -36.405 -4.463 1.00 41.78 N ANISOU 488 NH1 ARG C 58 5397 5017 5459 532 -1343 -150 N ATOM 489 NH2 ARG C 58 34.398 -35.079 -3.911 1.00 65.24 N ANISOU 489 NH2 ARG C 58 8055 7852 8882 1022 -1878 -535 N ATOM 490 N LEU C 59 36.266 -43.279 -5.318 1.00 24.16 N ANISOU 490 N LEU C 59 2641 3370 3170 -118 -492 -188 N ATOM 491 CA LEU C 59 36.973 -44.375 -5.974 1.00 23.66 C ANISOU 491 CA LEU C 59 2736 3287 2965 -226 -399 -147 C ATOM 492 C LEU C 59 36.310 -45.698 -5.633 1.00 27.67 C ANISOU 492 C LEU C 59 3124 3823 3568 -326 -323 -223 C ATOM 493 O LEU C 59 36.251 -46.598 -6.478 1.00 25.12 O ANISOU 493 O LEU C 59 2896 3464 3185 -398 -363 -251 O ATOM 494 CB LEU C 59 38.443 -44.444 -5.528 1.00 24.13 C ANISOU 494 CB LEU C 59 2899 3362 2907 -237 -194 -84 C ATOM 495 CG LEU C 59 39.261 -43.281 -6.071 1.00 23.53 C ANISOU 495 CG LEU C 59 3003 3281 2655 -250 -220 -37 C ATOM 496 CD1 LEU C 59 40.675 -43.378 -5.448 1.00 22.22 C ANISOU 496 CD1 LEU C 59 2831 3202 2408 -260 6 -58 C ATOM 497 CD2 LEU C 59 39.298 -43.317 -7.608 1.00 30.92 C ANISOU 497 CD2 LEU C 59 4170 4178 3399 -365 -356 -52 C ATOM 498 N ARG C 60 35.824 -45.818 -4.396 1.00 24.14 N ANISOU 498 N ARG C 60 2502 3435 3236 -380 -201 -269 N ATOM 499 CA ARG C 60 35.124 -47.037 -3.976 1.00 25.26 C ANISOU 499 CA ARG C 60 2597 3592 3408 -578 -111 -348 C ATOM 500 C ARG C 60 33.876 -47.222 -4.829 1.00 28.10 C ANISOU 500 C ARG C 60 2804 4027 3845 -631 -264 -511 C ATOM 501 O ARG C 60 33.649 -48.293 -5.387 1.00 29.05 O ANISOU 501 O ARG C 60 3020 4104 3912 -764 -270 -538 O ATOM 502 CB ARG C 60 34.756 -46.984 -2.486 1.00 29.44 C ANISOU 502 CB ARG C 60 2995 4202 3987 -719 65 -397 C ATOM 503 CG ARG C 60 34.252 -48.310 -1.965 1.00 34.08 C ANISOU 503 CG ARG C 60 3681 4761 4506 -1028 185 -445 C ATOM 504 CD ARG C 60 33.692 -48.227 -0.530 1.00 35.70 C ANISOU 504 CD ARG C 60 3773 5088 4704 -1289 381 -541 C ATOM 505 NE ARG C 60 32.470 -47.423 -0.445 1.00 42.83 N ANISOU 505 NE ARG C 60 4242 6257 5775 -1323 390 -826 N ATOM 506 CZ ARG C 60 31.272 -47.846 -0.844 1.00 42.97 C ANISOU 506 CZ ARG C 60 4038 6433 5854 -1509 377 -1086 C ATOM 507 NH1 ARG C 60 31.149 -49.061 -1.364 1.00 40.51 N ANISOU 507 NH1 ARG C 60 3950 6018 5425 -1710 378 -1044 N ATOM 508 NH2 ARG C 60 30.199 -47.057 -0.729 1.00 40.50 N ANISOU 508 NH2 ARG C 60 3265 6391 5733 -1480 347 -1430 N ATOM 509 N VAL C 61 33.092 -46.161 -4.975 1.00 30.00 N ANISOU 509 N VAL C 61 2815 4367 4217 -500 -428 -643 N ATOM 510 CA VAL C 61 31.854 -46.269 -5.759 1.00 30.81 C ANISOU 510 CA VAL C 61 2721 4564 4421 -502 -637 -858 C ATOM 511 C VAL C 61 32.130 -46.523 -7.244 1.00 30.92 C ANISOU 511 C VAL C 61 2984 4456 4308 -447 -841 -758 C ATOM 512 O VAL C 61 31.440 -47.319 -7.889 1.00 34.84 O ANISOU 512 O VAL C 61 3431 4999 4807 -561 -908 -872 O ATOM 513 CB VAL C 61 30.958 -45.036 -5.556 1.00 32.70 C ANISOU 513 CB VAL C 61 2645 4916 4865 -296 -851 -1087 C ATOM 514 CG1 VAL C 61 29.711 -45.126 -6.448 1.00 36.64 C ANISOU 514 CG1 VAL C 61 2919 5517 5484 -235 -1146 -1359 C ATOM 515 CG2 VAL C 61 30.559 -44.926 -4.083 1.00 37.89 C ANISOU 515 CG2 VAL C 61 3000 5757 5638 -427 -596 -1268 C ATOM 516 N GLN C 62 33.148 -45.861 -7.785 1.00 29.61 N ANISOU 516 N GLN C 62 3094 4153 4001 -326 -915 -566 N ATOM 517 CA GLN C 62 33.511 -46.059 -9.183 1.00 30.44 C ANISOU 517 CA GLN C 62 3475 4164 3926 -351 -1068 -487 C ATOM 518 C GLN C 62 34.010 -47.485 -9.439 1.00 30.10 C ANISOU 518 C GLN C 62 3541 4106 3788 -526 -866 -469 C ATOM 519 O GLN C 62 33.833 -48.027 -10.533 1.00 32.13 O ANISOU 519 O GLN C 62 3913 4343 3952 -602 -972 -502 O ATOM 520 CB GLN C 62 34.583 -45.048 -9.615 1.00 31.73 C ANISOU 520 CB GLN C 62 3941 4217 3898 -295 -1122 -324 C ATOM 521 CG GLN C 62 34.748 -44.988 -11.131 1.00 38.26 C ANISOU 521 CG GLN C 62 5085 4961 4492 -382 -1327 -279 C ATOM 522 CD GLN C 62 33.456 -44.578 -11.866 1.00 43.20 C ANISOU 522 CD GLN C 62 5693 5538 5183 -274 -1749 -370 C ATOM 523 OE1 GLN C 62 32.648 -43.794 -11.352 1.00 44.74 O ANISOU 523 OE1 GLN C 62 5701 5725 5575 -69 -1964 -465 O ATOM 524 NE2 GLN C 62 33.259 -45.117 -13.072 1.00 48.10 N ANISOU 524 NE2 GLN C 62 6492 6136 5650 -395 -1892 -383 N ATOM 525 N HIS C 63 34.650 -48.087 -8.439 1.00 29.17 N ANISOU 525 N HIS C 63 3421 3973 3688 -576 -613 -426 N ATOM 526 CA HIS C 63 35.175 -49.435 -8.603 1.00 32.80 C ANISOU 526 CA HIS C 63 4032 4353 4076 -683 -490 -431 C ATOM 527 C HIS C 63 34.004 -50.394 -8.801 1.00 37.04 C ANISOU 527 C HIS C 63 4490 4912 4670 -855 -525 -552 C ATOM 528 O HIS C 63 34.075 -51.308 -9.629 1.00 32.78 O ANISOU 528 O HIS C 63 4090 4309 4056 -938 -550 -592 O ATOM 529 CB HIS C 63 36.027 -49.807 -7.381 1.00 29.54 C ANISOU 529 CB HIS C 63 3680 3871 3674 -661 -308 -368 C ATOM 530 CG HIS C 63 37.034 -50.893 -7.632 1.00 27.28 C ANISOU 530 CG HIS C 63 3602 3454 3310 -640 -265 -391 C ATOM 531 ND1 HIS C 63 36.720 -52.232 -7.537 1.00 28.78 N ANISOU 531 ND1 HIS C 63 3932 3501 3502 -757 -269 -438 N ATOM 532 CD2 HIS C 63 38.366 -50.837 -7.891 1.00 30.54 C ANISOU 532 CD2 HIS C 63 4096 3857 3652 -508 -230 -426 C ATOM 533 CE1 HIS C 63 37.808 -52.955 -7.740 1.00 32.37 C ANISOU 533 CE1 HIS C 63 4556 3827 3916 -640 -284 -496 C ATOM 534 NE2 HIS C 63 38.821 -52.132 -7.960 1.00 29.34 N ANISOU 534 NE2 HIS C 63 4095 3554 3498 -484 -249 -520 N ATOM 535 N LEU C 64 32.917 -50.157 -8.063 1.00 30.67 N ANISOU 535 N LEU C 64 3437 4226 3991 -933 -514 -656 N ATOM 536 CA LEU C 64 31.666 -50.916 -8.236 1.00 33.01 C ANISOU 536 CA LEU C 64 3585 4622 4337 -1151 -530 -846 C ATOM 537 C LEU C 64 31.069 -50.780 -9.626 1.00 34.49 C ANISOU 537 C LEU C 64 3721 4863 4520 -1092 -781 -940 C ATOM 538 O LEU C 64 30.370 -51.681 -10.102 1.00 36.19 O ANISOU 538 O LEU C 64 3910 5120 4719 -1280 -793 -1071 O ATOM 539 CB LEU C 64 30.615 -50.434 -7.239 1.00 37.37 C ANISOU 539 CB LEU C 64 3786 5381 5031 -1246 -467 -1042 C ATOM 540 CG LEU C 64 30.968 -50.623 -5.768 1.00 40.50 C ANISOU 540 CG LEU C 64 4240 5753 5394 -1406 -208 -981 C ATOM 541 CD1 LEU C 64 29.805 -50.193 -4.891 1.00 42.72 C ANISOU 541 CD1 LEU C 64 4126 6308 5797 -1577 -111 -1267 C ATOM 542 CD2 LEU C 64 31.275 -52.079 -5.531 1.00 44.78 C ANISOU 542 CD2 LEU C 64 5128 6109 5776 -1681 -70 -897 C ATOM 543 N ARG C 65 31.287 -49.625 -10.250 1.00 35.51 N ANISOU 543 N ARG C 65 3869 4982 4642 -859 -1003 -879 N ATOM 544 CA ARG C 65 30.776 -49.389 -11.597 1.00 35.88 C ANISOU 544 CA ARG C 65 3960 5036 4637 -801 -1310 -939 C ATOM 545 C ARG C 65 31.640 -50.044 -12.658 1.00 35.30 C ANISOU 545 C ARG C 65 4224 4843 4347 -893 -1279 -820 C ATOM 546 O ARG C 65 31.121 -50.665 -13.585 1.00 36.93 O ANISOU 546 O ARG C 65 4464 5071 4498 -999 -1393 -910 O ATOM 547 CB ARG C 65 30.708 -47.880 -11.880 1.00 46.57 C ANISOU 547 CB ARG C 65 5337 6350 6009 -547 -1619 -902 C ATOM 548 CG ARG C 65 29.525 -47.165 -11.255 1.00 52.38 C ANISOU 548 CG ARG C 65 5677 7226 6998 -388 -1803 -1148 C ATOM 549 CD ARG C 65 29.456 -45.689 -11.683 1.00 56.13 C ANISOU 549 CD ARG C 65 6274 7571 7483 -88 -2219 -1116 C ATOM 550 NE ARG C 65 28.569 -44.936 -10.795 1.00 55.42 N ANISOU 550 NE ARG C 65 5771 7608 7677 118 -2343 -1387 N ATOM 551 CZ ARG C 65 28.976 -44.079 -9.861 1.00 61.45 C ANISOU 551 CZ ARG C 65 6498 8332 8516 243 -2255 -1341 C ATOM 552 NH1 ARG C 65 30.274 -43.826 -9.685 1.00 56.41 N ANISOU 552 NH1 ARG C 65 6215 7535 7683 182 -2051 -1020 N ATOM 553 NH2 ARG C 65 28.078 -43.458 -9.102 1.00 61.48 N ANISOU 553 NH2 ARG C 65 6076 8486 8799 425 -2370 -1668 N ATOM 554 N ASP C 66 32.955 -49.852 -12.562 1.00 37.29 N ANISOU 554 N ASP C 66 4695 5000 4475 -858 -1129 -667 N ATOM 555 CA ASP C 66 33.883 -50.381 -13.576 1.00 35.67 C ANISOU 555 CA ASP C 66 4758 4733 4061 -953 -1074 -641 C ATOM 556 C ASP C 66 34.091 -51.877 -13.457 1.00 35.05 C ANISOU 556 C ASP C 66 4706 4603 4006 -1067 -889 -724 C ATOM 557 O ASP C 66 34.356 -52.564 -14.446 1.00 36.51 O ANISOU 557 O ASP C 66 5037 4765 4069 -1167 -893 -798 O ATOM 558 CB ASP C 66 35.252 -49.694 -13.444 1.00 37.97 C ANISOU 558 CB ASP C 66 5206 5001 4220 -903 -947 -547 C ATOM 559 CG ASP C 66 35.167 -48.201 -13.649 1.00 41.26 C ANISOU 559 CG ASP C 66 5721 5404 4552 -836 -1146 -445 C ATOM 560 OD1 ASP C 66 34.215 -47.762 -14.329 1.00 48.06 O ANISOU 560 OD1 ASP C 66 6623 6240 5396 -818 -1453 -454 O ATOM 561 OD2 ASP C 66 36.054 -47.480 -13.149 1.00 43.69 O ANISOU 561 OD2 ASP C 66 6090 5706 4802 -797 -1029 -370 O ATOM 562 N HIS C 67 33.975 -52.380 -12.235 1.00 33.95 N ANISOU 562 N HIS C 67 4474 4423 4003 -1070 -742 -721 N ATOM 563 CA HIS C 67 34.231 -53.785 -11.959 1.00 33.16 C ANISOU 563 CA HIS C 67 4509 4185 3906 -1169 -619 -775 C ATOM 564 C HIS C 67 33.107 -54.370 -11.099 1.00 34.35 C ANISOU 564 C HIS C 67 4566 4338 4147 -1360 -568 -821 C ATOM 565 O HIS C 67 33.338 -54.730 -9.941 1.00 34.10 O ANISOU 565 O HIS C 67 4616 4201 4138 -1407 -448 -768 O ATOM 566 CB HIS C 67 35.564 -53.888 -11.232 1.00 33.73 C ANISOU 566 CB HIS C 67 4699 4143 3974 -1020 -501 -724 C ATOM 567 CG HIS C 67 36.683 -53.196 -11.955 1.00 35.70 C ANISOU 567 CG HIS C 67 4979 4469 4116 -901 -492 -747 C ATOM 568 ND1 HIS C 67 37.335 -52.095 -11.454 1.00 40.74 N ANISOU 568 ND1 HIS C 67 5555 5183 4742 -788 -442 -668 N ATOM 569 CD2 HIS C 67 37.224 -53.436 -13.173 1.00 35.38 C ANISOU 569 CD2 HIS C 67 5031 4468 3942 -947 -500 -874 C ATOM 570 CE1 HIS C 67 38.266 -51.706 -12.315 1.00 35.16 C ANISOU 570 CE1 HIS C 67 4915 4562 3882 -796 -408 -750 C ATOM 571 NE2 HIS C 67 38.209 -52.499 -13.368 1.00 42.22 N ANISOU 571 NE2 HIS C 67 5896 5448 4696 -901 -436 -885 N ATOM 572 N PRO C 68 31.891 -54.447 -11.658 1.00 36.10 N ANISOU 572 N PRO C 68 4626 4696 4394 -1507 -664 -946 N ATOM 573 CA PRO C 68 30.709 -54.785 -10.852 1.00 37.83 C ANISOU 573 CA PRO C 68 4663 5023 4686 -1752 -584 -1076 C ATOM 574 C PRO C 68 30.708 -56.190 -10.249 1.00 54.19 C ANISOU 574 C PRO C 68 7009 6908 6673 -2043 -423 -1085 C ATOM 575 O PRO C 68 29.999 -56.415 -9.274 1.00 47.49 O ANISOU 575 O PRO C 68 6097 6126 5821 -2316 -288 -1163 O ATOM 576 CB PRO C 68 29.547 -54.615 -11.841 1.00 39.89 C ANISOU 576 CB PRO C 68 4682 5489 4987 -1809 -767 -1269 C ATOM 577 CG PRO C 68 30.170 -54.787 -13.195 1.00 39.52 C ANISOU 577 CG PRO C 68 4855 5339 4823 -1705 -903 -1200 C ATOM 578 CD PRO C 68 31.536 -54.188 -13.072 1.00 37.08 C ANISOU 578 CD PRO C 68 4721 4907 4459 -1480 -862 -1012 C ATOM 579 N ASN C 69 31.478 -57.115 -10.806 1.00 39.83 N ANISOU 579 N ASN C 69 4322 5615 5198 -2706 101 -1023 N ATOM 580 CA ASN C 69 31.531 -58.468 -10.248 1.00 45.22 C ANISOU 580 CA ASN C 69 5277 5506 6398 -2814 -474 -918 C ATOM 581 C ASN C 69 32.849 -58.751 -9.520 1.00 43.74 C ANISOU 581 C ASN C 69 5376 5299 5943 -2429 -321 -1109 C ATOM 582 O ASN C 69 33.134 -59.894 -9.164 1.00 48.04 O ANISOU 582 O ASN C 69 6206 5218 6828 -2404 -815 -1162 O ATOM 583 CB ASN C 69 31.296 -59.507 -11.333 1.00 51.69 C ANISOU 583 CB ASN C 69 6373 5733 7535 -2727 -1431 -1450 C ATOM 584 CG ASN C 69 29.854 -59.538 -11.789 1.00 55.10 C ANISOU 584 CG ASN C 69 6517 5945 8472 -3140 -1705 -1087 C ATOM 585 OD1 ASN C 69 29.030 -58.781 -11.278 1.00 52.42 O ANISOU 585 OD1 ASN C 69 5763 5926 8227 -3308 -1076 -430 O ATOM 586 ND2 ASN C 69 29.547 -60.391 -12.769 1.00 62.39 N ANISOU 586 ND2 ASN C 69 7721 6418 9566 -2955 -2464 -1493 N ATOM 587 N TYR C 70 33.642 -57.707 -9.297 1.00 38.07 N ANISOU 587 N TYR C 70 4567 5226 4671 -2150 305 -1178 N ATOM 588 CA TYR C 70 34.881 -57.861 -8.554 1.00 36.67 C ANISOU 588 CA TYR C 70 4610 5042 4282 -1820 445 -1278 C ATOM 589 C TYR C 70 34.581 -58.352 -7.151 1.00 38.51 C ANISOU 589 C TYR C 70 4930 4850 4851 -2099 508 -677 C ATOM 590 O TYR C 70 33.597 -57.929 -6.523 1.00 39.53 O ANISOU 590 O TYR C 70 4841 5053 5125 -2439 820 -40 O ATOM 591 CB TYR C 70 35.632 -56.525 -8.472 1.00 30.98 C ANISOU 591 CB TYR C 70 3698 5023 3051 -1576 1023 -1294 C ATOM 592 CG TYR C 70 36.813 -56.515 -7.509 1.00 29.95 C ANISOU 592 CG TYR C 70 3743 4858 2778 -1322 1157 -1245 C ATOM 593 CD1 TYR C 70 38.090 -56.908 -7.936 1.00 36.37 C ANISOU 593 CD1 TYR C 70 4678 5716 3424 -847 975 -1676 C ATOM 594 CD2 TYR C 70 36.668 -56.040 -6.222 1.00 35.44 C ANISOU 594 CD2 TYR C 70 4487 5470 3509 -1417 1382 -734 C ATOM 595 CE1 TYR C 70 39.178 -56.874 -7.050 1.00 34.71 C ANISOU 595 CE1 TYR C 70 4585 5438 3167 -634 1038 -1554 C ATOM 596 CE2 TYR C 70 37.738 -55.999 -5.342 1.00 42.38 C ANISOU 596 CE2 TYR C 70 5549 6249 4305 -1148 1377 -690 C ATOM 597 CZ TYR C 70 38.983 -56.412 -5.766 1.00 35.68 C ANISOU 597 CZ TYR C 70 4777 5453 3327 -847 1253 -1113 C ATOM 598 OH TYR C 70 40.037 -56.365 -4.876 1.00 40.04 O ANISOU 598 OH TYR C 70 5487 5892 3835 -624 1227 -1026 O ATOM 599 N LYS C 71 35.397 -59.285 -6.680 1.00 40.37 N ANISOU 599 N LYS C 71 5477 4666 5197 -1899 219 -836 N ATOM 600 CA LYS C 71 35.304 -59.753 -5.307 1.00 41.76 C ANISOU 600 CA LYS C 71 5755 4490 5621 -2053 315 -272 C ATOM 601 C LYS C 71 36.717 -59.858 -4.774 1.00 48.76 C ANISOU 601 C LYS C 71 6920 5395 6210 -1640 376 -563 C ATOM 602 O LYS C 71 37.572 -60.493 -5.391 1.00 45.91 O ANISOU 602 O LYS C 71 6763 4876 5804 -1330 9 -1119 O ATOM 603 CB LYS C 71 34.584 -61.111 -5.231 1.00 52.00 C ANISOU 603 CB LYS C 71 7110 5027 7619 -2374 -288 -14 C ATOM 604 CG LYS C 71 33.120 -61.066 -5.702 1.00 56.77 C ANISOU 604 CG LYS C 71 7368 5530 8671 -2850 -442 419 C ATOM 605 CD LYS C 71 32.302 -62.287 -5.269 1.00 72.27 C ANISOU 605 CD LYS C 71 9250 6755 11457 -3219 -966 1007 C ATOM 606 CE LYS C 71 32.313 -63.402 -6.310 1.00 81.31 C ANISOU 606 CE LYS C 71 10634 7273 12986 -3176 -1926 419 C ATOM 607 NZ LYS C 71 33.670 -63.984 -6.511 1.00 83.03 N ANISOU 607 NZ LYS C 71 11378 7196 12975 -2768 -2319 -363 N ATOM 608 N TYR C 72 36.969 -59.205 -3.645 1.00 37.35 N ANISOU 608 N TYR C 72 5507 4156 4530 -1571 814 -183 N ATOM 609 CA TYR C 72 38.286 -59.256 -3.014 1.00 36.11 C ANISOU 609 CA TYR C 72 5605 3970 4146 -1215 826 -380 C ATOM 610 C TYR C 72 38.476 -60.661 -2.432 1.00 40.58 C ANISOU 610 C TYR C 72 6441 3894 5085 -1228 459 -303 C ATOM 611 O TYR C 72 37.665 -61.126 -1.630 1.00 43.33 O ANISOU 611 O TYR C 72 6784 3944 5737 -1469 491 276 O ATOM 612 CB TYR C 72 38.404 -58.187 -1.918 1.00 34.98 C ANISOU 612 CB TYR C 72 5511 4117 3663 -1103 1253 -5 C ATOM 613 CG TYR C 72 39.716 -58.232 -1.140 1.00 33.76 C ANISOU 613 CG TYR C 72 5639 3848 3342 -765 1173 -142 C ATOM 614 CD1 TYR C 72 40.934 -58.361 -1.802 1.00 34.01 C ANISOU 614 CD1 TYR C 72 5649 3944 3329 -520 955 -628 C ATOM 615 CD2 TYR C 72 39.730 -58.138 0.247 1.00 35.89 C ANISOU 615 CD2 TYR C 72 6188 3970 3480 -627 1314 261 C ATOM 616 CE1 TYR C 72 42.131 -58.412 -1.100 1.00 36.86 C ANISOU 616 CE1 TYR C 72 6212 4182 3609 -241 846 -684 C ATOM 617 CE2 TYR C 72 40.928 -58.193 0.967 1.00 35.87 C ANISOU 617 CE2 TYR C 72 6468 3809 3352 -321 1161 125 C ATOM 618 CZ TYR C 72 42.131 -58.314 0.266 1.00 34.41 C ANISOU 618 CZ TYR C 72 6202 3659 3214 -176 913 -343 C ATOM 619 OH TYR C 72 43.316 -58.369 0.967 1.00 40.29 O ANISOU 619 OH TYR C 72 7171 4234 3903 97 731 -412 O ATOM 620 N ARG C 73 39.531 -61.340 -2.871 1.00 41.86 N ANISOU 620 N ARG C 73 6802 3870 5231 -933 116 -828 N ATOM 621 CA ARG C 73 39.830 -62.692 -2.423 1.00 46.24 C ANISOU 621 CA ARG C 73 7646 3793 6130 -902 -299 -846 C ATOM 622 C ARG C 73 41.294 -62.807 -2.004 1.00 47.71 C ANISOU 622 C ARG C 73 8060 4008 6062 -481 -293 -1122 C ATOM 623 O ARG C 73 42.128 -63.252 -2.791 1.00 50.26 O ANISOU 623 O ARG C 73 8490 4321 6285 -132 -566 -1644 O ATOM 624 CB ARG C 73 39.545 -63.700 -3.546 1.00 55.69 C ANISOU 624 CB ARG C 73 8943 4579 7638 -912 -930 -1276 C ATOM 625 CG ARG C 73 38.107 -63.712 -4.046 1.00 62.06 C ANISOU 625 CG ARG C 73 9518 5242 8820 -1362 -1105 -1005 C ATOM 626 CD ARG C 73 37.368 -64.950 -3.537 1.00 77.30 C ANISOU 626 CD ARG C 73 11510 6378 11482 -1733 -1622 -562 C ATOM 627 NE ARG C 73 35.911 -64.837 -3.625 1.00 84.86 N ANISOU 627 NE ARG C 73 12106 7224 12913 -2258 -1672 44 N ATOM 628 CZ ARG C 73 35.168 -64.091 -2.808 1.00 84.59 C ANISOU 628 CZ ARG C 73 11735 7550 12855 -2498 -1050 826 C ATOM 629 NH1 ARG C 73 35.747 -63.367 -1.852 1.00 74.82 N ANISOU 629 NH1 ARG C 73 10562 6761 11105 -2233 -403 1006 N ATOM 630 NH2 ARG C 73 33.847 -64.057 -2.956 1.00 84.15 N ANISOU 630 NH2 ARG C 73 11298 7410 13266 -2939 -1109 1435 N ATOM 631 N PRO C 74 41.612 -62.407 -0.765 1.00 43.26 N ANISOU 631 N PRO C 74 7586 3485 5365 -443 -1 -751 N ATOM 632 CA PRO C 74 43.002 -62.481 -0.292 1.00 48.41 C ANISOU 632 CA PRO C 74 8435 4123 5836 -79 -47 -953 C ATOM 633 C PRO C 74 43.458 -63.921 -0.071 1.00 57.81 C ANISOU 633 C PRO C 74 9916 4737 7311 26 -450 -1101 C ATOM 634 O PRO C 74 42.632 -64.750 0.328 1.00 60.67 O ANISOU 634 O PRO C 74 10359 4641 8049 -246 -622 -798 O ATOM 635 CB PRO C 74 42.949 -61.770 1.061 1.00 43.51 C ANISOU 635 CB PRO C 74 7927 3574 5030 -74 258 -485 C ATOM 636 CG PRO C 74 41.531 -61.957 1.526 1.00 44.75 C ANISOU 636 CG PRO C 74 8033 3599 5371 -381 424 56 C ATOM 637 CD PRO C 74 40.693 -61.892 0.267 1.00 42.95 C ANISOU 637 CD PRO C 74 7502 3508 5309 -654 355 -102 C ATOM 638 N ARG C 75 44.732 -64.199 -0.360 1.00 62.70 N ANISOU 638 N ARG C 75 10643 5390 7789 423 -609 -1496 N ATOM 639 CA ARG C 75 45.466 -65.377 0.140 1.00 64.61 C ANISOU 639 CA ARG C 75 11206 5139 8202 617 -923 -1607 C ATOM 640 C ARG C 75 46.799 -65.458 -0.587 1.00 70.83 C ANISOU 640 C ARG C 75 11915 6237 8758 1110 -1000 -2007 C ATOM 641 O ARG C 75 46.869 -65.200 -1.792 1.00 75.02 O ANISOU 641 O ARG C 75 12234 7155 9114 1315 -993 -2280 O ATOM 642 CB ARG C 75 44.692 -66.692 -0.035 1.00 77.95 C ANISOU 642 CB ARG C 75 13088 6193 10338 413 -1379 -1633 C ATOM 643 CG ARG C 75 45.133 -67.815 0.906 1.00 86.69 C ANISOU 643 CG ARG C 75 14371 6874 11692 440 -1571 -1449 C ATOM 644 CD ARG C 75 45.160 -67.360 2.365 1.00 84.43 C ANISOU 644 CD ARG C 75 14216 6513 11350 358 -1238 -934 C ATOM 645 NE ARG C 75 45.751 -68.370 3.241 1.00 90.96 N ANISOU 645 NE ARG C 75 15152 7071 12340 454 -1372 -801 N ATOM 646 CZ ARG C 75 47.058 -68.598 3.334 1.00 92.85 C ANISOU 646 CZ ARG C 75 15405 7496 12377 780 -1406 -1075 C ATOM 647 NH1 ARG C 75 47.904 -67.890 2.595 1.00 91.64 N ANISOU 647 NH1 ARG C 75 15113 7803 11905 1050 -1315 -1405 N ATOM 648 NH2 ARG C 75 47.519 -69.532 4.157 1.00 94.57 N ANISOU 648 NH2 ARG C 75 15735 7452 12745 830 -1522 -942 N TER 649 ARG C 75 ATOM 650 O5' DC A 0 70.855 -56.136 -18.870 1.00 87.12 O ANISOU 650 O5' DC A 0 8917 11606 12580 2598 364 3136 O ATOM 651 C5' DC A 0 70.531 -56.724 -20.126 1.00 84.13 C ANISOU 651 C5' DC A 0 8885 11648 11434 2499 251 3817 C ATOM 652 C4' DC A 0 69.789 -58.039 -19.953 1.00 77.72 C ANISOU 652 C4' DC A 0 8649 11365 9516 2266 6 3767 C ATOM 653 O4' DC A 0 70.674 -59.029 -19.384 1.00 77.62 O ANISOU 653 O4' DC A 0 9357 11218 8917 2253 193 3203 O ATOM 654 C3' DC A 0 68.592 -57.985 -19.017 1.00 74.46 C ANISOU 654 C3' DC A 0 7854 11136 9301 2059 -190 3365 C ATOM 655 O3' DC A 0 67.432 -57.793 -19.780 1.00 80.74 O ANISOU 655 O3' DC A 0 8376 12362 9941 1828 -463 3916 O ATOM 656 C2' DC A 0 68.545 -59.366 -18.379 1.00 74.68 C ANISOU 656 C2' DC A 0 8669 11362 8342 1750 -197 2750 C ATOM 657 C1' DC A 0 69.998 -59.810 -18.414 1.00 74.50 C ANISOU 657 C1' DC A 0 9201 11028 8077 1973 92 2599 C ATOM 658 N1 DC A 0 70.682 -59.646 -17.102 1.00 70.72 N ANISOU 658 N1 DC A 0 8540 10223 8107 2229 277 1946 N ATOM 659 C2 DC A 0 70.586 -60.671 -16.154 1.00 66.94 C ANISOU 659 C2 DC A 0 8531 9890 7013 2057 309 1352 C ATOM 660 O2 DC A 0 69.938 -61.688 -16.427 1.00 66.90 O ANISOU 660 O2 DC A 0 9092 10206 6121 1686 208 1366 O ATOM 661 N3 DC A 0 71.208 -60.515 -14.959 1.00 64.34 N ANISOU 661 N3 DC A 0 7999 9367 7081 2296 459 782 N ATOM 662 C4 DC A 0 71.901 -59.406 -14.707 1.00 61.25 C ANISOU 662 C4 DC A 0 6978 8629 7667 2650 569 725 C ATOM 663 N4 DC A 0 72.506 -59.312 -13.518 1.00 59.79 N ANISOU 663 N4 DC A 0 6618 8323 7778 2782 681 106 N ATOM 664 C5 DC A 0 72.010 -58.351 -15.663 1.00 66.48 C ANISOU 664 C5 DC A 0 7162 9055 9043 2817 570 1305 C ATOM 665 C6 DC A 0 71.390 -58.508 -16.837 1.00 70.02 C ANISOU 665 C6 DC A 0 7807 9723 9075 2619 424 1937 C ATOM 666 P DA A 1 66.088 -57.278 -19.070 1.00 67.93 P ANISOU 666 P DA A 1 6048 10896 8868 1712 -657 3781 P ATOM 667 OP1 DA A 1 65.124 -56.891 -20.120 1.00 67.60 O ANISOU 667 OP1 DA A 1 5646 11270 8769 1559 -897 4541 O ATOM 668 OP2 DA A 1 66.505 -56.301 -18.033 1.00 67.26 O ANISOU 668 OP2 DA A 1 5341 10258 9956 2070 -428 3352 O ATOM 669 O5' DA A 1 65.535 -58.574 -18.301 1.00 64.46 O ANISOU 669 O5' DA A 1 6228 10764 7501 1292 -767 3119 O ATOM 670 C5' DA A 1 64.900 -59.655 -18.973 1.00 68.08 C ANISOU 670 C5' DA A 1 7294 11744 6829 817 -981 3260 C ATOM 671 C4' DA A 1 64.338 -60.547 -17.892 1.00 70.21 C ANISOU 671 C4' DA A 1 7869 12135 6671 527 -1007 2573 C ATOM 672 O4' DA A 1 65.470 -61.082 -17.175 1.00 68.68 O ANISOU 672 O4' DA A 1 8185 11585 6325 711 -718 2036 O ATOM 673 C3' DA A 1 63.568 -59.776 -16.825 1.00 74.29 C ANISOU 673 C3' DA A 1 7601 12574 8054 645 -1045 2299 C ATOM 674 O3' DA A 1 62.176 -59.572 -17.153 1.00 83.63 O ANISOU 674 O3' DA A 1 8338 14187 9250 368 -1337 2650 O ATOM 675 C2' DA A 1 63.807 -60.568 -15.551 1.00 65.34 C ANISOU 675 C2' DA A 1 6865 11335 6625 596 -886 1511 C ATOM 676 C1' DA A 1 65.188 -61.140 -15.786 1.00 63.54 C ANISOU 676 C1' DA A 1 7329 10853 5961 748 -654 1410 C ATOM 677 N9 DA A 1 66.220 -60.438 -15.035 1.00 60.53 N ANISOU 677 N9 DA A 1 6632 10029 6337 1205 -415 1094 N ATOM 678 C8 DA A 1 66.813 -59.230 -15.286 1.00 59.77 C ANISOU 678 C8 DA A 1 5946 9582 7181 1585 -321 1342 C ATOM 679 N7 DA A 1 67.721 -58.904 -14.387 1.00 54.77 N ANISOU 679 N7 DA A 1 5156 8617 7039 1895 -103 854 N ATOM 680 C5 DA A 1 67.716 -59.965 -13.501 1.00 52.62 C ANISOU 680 C5 DA A 1 5398 8531 6065 1735 -59 307 C ATOM 681 C6 DA A 1 68.446 -60.253 -12.332 1.00 48.24 C ANISOU 681 C6 DA A 1 4949 7887 5492 1913 125 -324 C ATOM 682 N6 DA A 1 69.386 -59.456 -11.811 1.00 43.90 N ANISOU 682 N6 DA A 1 3974 7027 5678 2273 287 -602 N ATOM 683 N1 DA A 1 68.173 -61.417 -11.706 1.00 47.68 N ANISOU 683 N1 DA A 1 5422 8090 4604 1696 143 -654 N ATOM 684 C2 DA A 1 67.250 -62.243 -12.196 1.00 43.45 C ANISOU 684 C2 DA A 1 5307 7840 3361 1300 1 -434 C ATOM 685 N3 DA A 1 66.509 -62.079 -13.287 1.00 55.03 N ANISOU 685 N3 DA A 1 6722 9439 4747 1063 -202 89 N ATOM 686 C4 DA A 1 66.796 -60.915 -13.890 1.00 54.52 C ANISOU 686 C4 DA A 1 6107 9151 5459 1317 -228 459 C ATOM 687 P DC A 2 61.054 -60.697 -16.874 1.00 83.02 P ANISOU 687 P DC A 2 8631 14593 8320 -183 -1541 2374 P ATOM 688 OP1 DC A 2 61.527 -61.996 -17.402 1.00 85.49 O ANISOU 688 OP1 DC A 2 9926 15044 7510 -502 -1508 2253 O ATOM 689 OP2 DC A 2 59.783 -60.111 -17.337 1.00 90.91 O ANISOU 689 OP2 DC A 2 8948 15988 9604 -342 -1832 2885 O ATOM 690 O5' DC A 2 60.952 -60.838 -15.285 1.00 76.06 O ANISOU 690 O5' DC A 2 7647 13499 7752 -92 -1368 1615 O ATOM 691 C5' DC A 2 60.399 -62.050 -14.810 1.00 71.85 C ANISOU 691 C5' DC A 2 7648 13233 6417 -503 -1404 1224 C ATOM 692 C4' DC A 2 60.904 -62.438 -13.441 1.00 66.20 C ANISOU 692 C4' DC A 2 7139 12274 5741 -333 -1139 521 C ATOM 693 O4' DC A 2 62.289 -62.059 -13.291 1.00 61.80 O ANISOU 693 O4' DC A 2 6678 11298 5506 99 -899 389 O ATOM 694 C3' DC A 2 60.247 -61.730 -12.256 1.00 71.61 C ANISOU 694 C3' DC A 2 7094 12935 7177 -167 -1107 174 C ATOM 695 O3' DC A 2 58.796 -62.026 -12.035 1.00 80.44 O ANISOU 695 O3' DC A 2 7981 14451 8133 -543 -1300 194 O ATOM 696 C2' DC A 2 61.269 -61.995 -11.146 1.00 64.94 C ANISOU 696 C2' DC A 2 6514 11829 6331 118 -813 -444 C ATOM 697 C1' DC A 2 62.586 -62.072 -11.908 1.00 58.88 C ANISOU 697 C1' DC A 2 6198 10788 5385 311 -701 -238 C ATOM 698 N1 DC A 2 63.569 -61.001 -11.535 1.00 58.28 N ANISOU 698 N1 DC A 2 5652 10320 6171 800 -530 -393 N ATOM 699 C2 DC A 2 64.410 -61.269 -10.454 1.00 52.07 C ANISOU 699 C2 DC A 2 5033 9412 5340 1024 -305 -973 C ATOM 700 O2 DC A 2 64.279 -62.359 -9.896 1.00 60.20 O ANISOU 700 O2 DC A 2 6583 10653 5638 838 -245 -1252 O ATOM 701 N3 DC A 2 65.335 -60.353 -10.060 1.00 52.22 N ANISOU 701 N3 DC A 2 4625 9109 6107 1424 -153 -1198 N ATOM 702 C4 DC A 2 65.432 -59.196 -10.714 1.00 48.89 C ANISOU 702 C4 DC A 2 3638 8414 6525 1610 -181 -846 C ATOM 703 N4 DC A 2 66.356 -58.316 -10.303 1.00 45.81 N ANISOU 703 N4 DC A 2 2918 7602 6885 1906 2 -1065 N ATOM 704 C5 DC A 2 64.573 -58.900 -11.826 1.00 53.84 C ANISOU 704 C5 DC A 2 4084 9145 7230 1427 -386 -181 C ATOM 705 C6 DC A 2 63.662 -59.815 -12.200 1.00 53.18 C ANISOU 705 C6 DC A 2 4410 9455 6339 1021 -575 18 C ATOM 706 P DT A 3 58.225 -63.257 -11.146 1.00 86.65 P ANISOU 706 P DT A 3 9228 15474 8221 -884 -1236 -276 P ATOM 707 OP1 DT A 3 58.902 -64.155 -12.114 1.00 91.35 O ANISOU 707 OP1 DT A 3 10659 15915 8132 -1060 -1181 -76 O ATOM 708 OP2 DT A 3 56.997 -62.437 -11.277 1.00 90.42 O ANISOU 708 OP2 DT A 3 8901 16175 9280 -963 -1456 23 O ATOM 709 O5' DT A 3 58.991 -63.029 -9.769 1.00 83.76 O ANISOU 709 O5' DT A 3 8759 14843 8222 -469 -935 -891 O ATOM 710 C5' DT A 3 59.475 -64.184 -9.107 1.00 81.16 C ANISOU 710 C5' DT A 3 9127 14437 7272 -527 -701 -1247 C ATOM 711 C4' DT A 3 59.997 -63.762 -7.762 1.00 79.89 C ANISOU 711 C4' DT A 3 8648 14244 7463 -141 -499 -1816 C ATOM 712 O4' DT A 3 61.079 -62.828 -7.959 1.00 79.26 O ANISOU 712 O4' DT A 3 8311 13851 7954 266 -434 -1825 O ATOM 713 C3' DT A 3 58.934 -63.030 -6.961 1.00 82.56 C ANISOU 713 C3' DT A 3 8209 14765 8394 -114 -550 -2033 C ATOM 714 O3' DT A 3 58.605 -63.802 -5.828 1.00 85.26 O ANISOU 714 O3' DT A 3 8752 15212 8430 -177 -353 -2365 O ATOM 715 C2' DT A 3 59.570 -61.697 -6.580 1.00 81.25 C ANISOU 715 C2' DT A 3 7389 14313 9171 345 -452 -2257 C ATOM 716 C1' DT A 3 61.034 -61.918 -6.887 1.00 75.39 C ANISOU 716 C1' DT A 3 7134 13316 8193 563 -331 -2274 C ATOM 717 N1 DT A 3 61.706 -60.679 -7.301 1.00 72.74 N ANISOU 717 N1 DT A 3 6298 12619 8722 891 -313 -2165 N ATOM 718 C2 DT A 3 62.823 -60.321 -6.598 1.00 62.35 C ANISOU 718 C2 DT A 3 5042 10990 7656 1173 -134 -2541 C ATOM 719 O2 DT A 3 63.240 -61.001 -5.678 1.00 67.22 O ANISOU 719 O2 DT A 3 6051 11682 7807 1140 -85 -2860 O ATOM 720 N3 DT A 3 63.418 -59.159 -7.025 1.00 57.88 N ANISOU 720 N3 DT A 3 4309 9828 7856 1306 -98 -2256 N ATOM 721 C4 DT A 3 62.990 -58.340 -8.060 1.00 56.97 C ANISOU 721 C4 DT A 3 3791 9525 8329 1322 -171 -1701 C ATOM 722 O4 DT A 3 63.586 -57.309 -8.374 1.00 53.57 O ANISOU 722 O4 DT A 3 3237 8604 8514 1454 -59 -1404 O ATOM 723 C5 DT A 3 61.799 -58.782 -8.750 1.00 66.96 C ANISOU 723 C5 DT A 3 4809 11307 9325 1119 -408 -1396 C ATOM 724 C7 DT A 3 61.245 -57.977 -9.890 1.00 65.21 C ANISOU 724 C7 DT A 3 4149 10976 9651 1099 -556 -691 C ATOM 725 C6 DT A 3 61.212 -59.919 -8.343 1.00 71.35 C ANISOU 725 C6 DT A 3 5728 12325 9055 848 -479 -1607 C ATOM 726 P DA A 4 57.309 -63.441 -4.953 1.00 98.63 P ANISOU 726 P DA A 4 12462 12557 12457 -1275 2606 -2647 P ATOM 727 OP1 DA A 4 56.395 -64.603 -5.039 1.00101.56 O ANISOU 727 OP1 DA A 4 12885 12777 12926 -1897 3085 -3337 O ATOM 728 OP2 DA A 4 56.817 -62.096 -5.335 1.00 94.27 O ANISOU 728 OP2 DA A 4 11330 12846 11641 -1006 2329 -2580 O ATOM 729 O5' DA A 4 57.900 -63.303 -3.474 1.00 77.76 O ANISOU 729 O5' DA A 4 10465 9162 9917 -1161 2557 -2026 O ATOM 730 C5' DA A 4 59.116 -63.977 -3.182 1.00 74.78 C ANISOU 730 C5' DA A 4 10632 8072 9709 -884 2527 -1719 C ATOM 731 C4' DA A 4 59.821 -63.299 -2.029 1.00 67.20 C ANISOU 731 C4' DA A 4 9992 6785 8754 -484 2239 -1143 C ATOM 732 O4' DA A 4 60.600 -62.178 -2.509 1.00 59.16 O ANISOU 732 O4' DA A 4 8507 6178 7794 -13 1827 -887 O ATOM 733 C3' DA A 4 58.894 -62.734 -0.970 1.00 69.34 C ANISOU 733 C3' DA A 4 10348 7109 8887 -703 2304 -1034 C ATOM 734 O3' DA A 4 59.500 -63.039 0.265 1.00 72.27 O ANISOU 734 O3' DA A 4 11405 6800 9254 -435 2283 -666 O ATOM 735 C2' DA A 4 58.856 -61.227 -1.263 1.00 60.29 C ANISOU 735 C2' DA A 4 8566 6663 7679 -451 1929 -854 C ATOM 736 C1' DA A 4 60.244 -60.980 -1.834 1.00 57.48 C ANISOU 736 C1' DA A 4 8084 6250 7505 71 1642 -641 C ATOM 737 N9 DA A 4 60.385 -59.927 -2.841 1.00 52.40 N ANISOU 737 N9 DA A 4 6812 6233 6864 322 1490 -613 N ATOM 738 C8 DA A 4 59.606 -59.682 -3.937 1.00 54.66 C ANISOU 738 C8 DA A 4 6636 7178 6954 223 1598 -901 C ATOM 739 N7 DA A 4 60.025 -58.681 -4.679 1.00 57.78 N ANISOU 739 N7 DA A 4 6636 7968 7351 634 1500 -728 N ATOM 740 C5 DA A 4 61.165 -58.241 -4.025 1.00 46.17 C ANISOU 740 C5 DA A 4 5310 6047 6185 934 1334 -362 C ATOM 741 C6 DA A 4 62.084 -57.206 -4.293 1.00 45.32 C ANISOU 741 C6 DA A 4 4934 5968 6318 1370 1275 -102 C ATOM 742 N6 DA A 4 61.991 -56.384 -5.346 1.00 42.46 N ANISOU 742 N6 DA A 4 4193 6077 5864 1640 1433 -56 N ATOM 743 N1 DA A 4 63.117 -57.046 -3.436 1.00 43.12 N ANISOU 743 N1 DA A 4 4798 5205 6380 1565 1097 66 N ATOM 744 C2 DA A 4 63.220 -57.870 -2.388 1.00 49.60 C ANISOU 744 C2 DA A 4 6074 5576 7195 1440 953 45 C ATOM 745 N3 DA A 4 62.420 -58.879 -2.036 1.00 49.85 N ANISOU 745 N3 DA A 4 6500 5463 6977 1078 1059 -91 N ATOM 746 C4 DA A 4 61.405 -59.006 -2.902 1.00 50.13 C ANISOU 746 C4 DA A 4 6312 5957 6780 784 1268 -317 C ATOM 747 P DG A 5 58.727 -62.756 1.642 1.00 69.52 P ANISOU 747 P DG A 5 11430 6241 8745 -577 2422 -477 P ATOM 748 OP1 DG A 5 59.222 -63.759 2.614 1.00 77.84 O ANISOU 748 OP1 DG A 5 13404 6441 9730 -342 2662 -267 O ATOM 749 OP2 DG A 5 57.277 -62.639 1.349 1.00 71.11 O ANISOU 749 OP2 DG A 5 11269 6857 8893 -1203 2739 -868 O ATOM 750 O5' DG A 5 59.254 -61.303 2.083 1.00 55.55 O ANISOU 750 O5' DG A 5 9288 4855 6964 -114 1862 -114 O ATOM 751 C5' DG A 5 60.631 -61.218 2.424 1.00 54.23 C ANISOU 751 C5' DG A 5 9300 4410 6893 508 1502 138 C ATOM 752 C4' DG A 5 61.013 -59.790 2.694 1.00 48.27 C ANISOU 752 C4' DG A 5 8039 4068 6233 828 1072 326 C ATOM 753 O4' DG A 5 61.087 -59.078 1.448 1.00 46.57 O ANISOU 753 O4' DG A 5 7121 4396 6179 774 1005 214 O ATOM 754 C3' DG A 5 60.024 -59.042 3.573 1.00 49.32 C ANISOU 754 C3' DG A 5 8141 4400 6198 625 1089 445 C ATOM 755 O3' DG A 5 60.702 -58.773 4.783 1.00 50.21 O ANISOU 755 O3' DG A 5 8567 4234 6278 1117 799 668 O ATOM 756 C2' DG A 5 59.677 -57.768 2.804 1.00 43.45 C ANISOU 756 C2' DG A 5 6613 4351 5545 524 966 416 C ATOM 757 C1' DG A 5 60.717 -57.737 1.691 1.00 43.87 C ANISOU 757 C1' DG A 5 6333 4491 5844 801 858 346 C ATOM 758 N9 DG A 5 60.234 -57.206 0.422 1.00 42.13 N ANISOU 758 N9 DG A 5 5557 4846 5603 652 982 217 N ATOM 759 C8 DG A 5 59.198 -57.649 -0.367 1.00 42.20 C ANISOU 759 C8 DG A 5 5441 5197 5397 271 1233 -64 C ATOM 760 N7 DG A 5 59.056 -56.951 -1.462 1.00 40.94 N ANISOU 760 N7 DG A 5 4774 5596 5185 401 1252 -125 N ATOM 761 C5 DG A 5 60.046 -55.981 -1.386 1.00 38.50 C ANISOU 761 C5 DG A 5 4273 5228 5127 827 1092 166 C ATOM 762 C6 DG A 5 60.369 -54.928 -2.276 1.00 36.95 C ANISOU 762 C6 DG A 5 3635 5398 5007 1160 1161 281 C ATOM 763 O6 DG A 5 59.823 -54.644 -3.354 1.00 39.50 O ANISOU 763 O6 DG A 5 3680 6241 5088 1239 1327 183 O ATOM 764 N1 DG A 5 61.450 -54.170 -1.820 1.00 35.47 N ANISOU 764 N1 DG A 5 3349 4918 5211 1476 1065 490 N ATOM 765 C2 DG A 5 62.129 -54.404 -0.646 1.00 37.13 C ANISOU 765 C2 DG A 5 3807 4652 5650 1532 823 526 C ATOM 766 N2 DG A 5 63.141 -53.569 -0.367 1.00 39.03 N ANISOU 766 N2 DG A 5 3793 4729 6307 1852 750 583 N ATOM 767 N3 DG A 5 61.843 -55.396 0.197 1.00 38.99 N ANISOU 767 N3 DG A 5 4517 4584 5714 1336 706 470 N ATOM 768 C4 DG A 5 60.785 -56.128 -0.239 1.00 40.47 C ANISOU 768 C4 DG A 5 4847 4954 5577 957 899 319 C ATOM 769 P DC A 6 59.919 -58.143 6.033 1.00 53.51 P ANISOU 769 P DC A 6 9148 4696 6487 1070 770 848 P ATOM 770 OP1 DC A 6 60.720 -58.547 7.218 1.00 51.60 O ANISOU 770 OP1 DC A 6 9523 3983 6099 1685 570 1000 O ATOM 771 OP2 DC A 6 58.481 -58.494 5.933 1.00 59.82 O ANISOU 771 OP2 DC A 6 10062 5550 7116 419 1228 745 O ATOM 772 O5' DC A 6 60.003 -56.543 5.792 1.00 42.02 O ANISOU 772 O5' DC A 6 6877 3848 5239 1136 452 882 O ATOM 773 C5' DC A 6 61.272 -55.933 5.906 1.00 45.49 C ANISOU 773 C5' DC A 6 7019 4307 5960 1669 72 872 C ATOM 774 C4' DC A 6 61.130 -54.483 5.527 1.00 37.29 C ANISOU 774 C4' DC A 6 5248 3770 5150 1597 -2 887 C ATOM 775 O4' DC A 6 60.715 -54.434 4.142 1.00 36.04 O ANISOU 775 O4' DC A 6 4744 3925 5025 1286 262 821 O ATOM 776 C3' DC A 6 60.073 -53.728 6.320 1.00 35.70 C ANISOU 776 C3' DC A 6 5011 3803 4751 1375 14 1029 C ATOM 777 O3' DC A 6 60.578 -52.457 6.735 1.00 38.66 O ANISOU 777 O3' DC A 6 4915 4376 5398 1651 -223 1041 O ATOM 778 C2' DC A 6 58.996 -53.478 5.263 1.00 34.05 C ANISOU 778 C2' DC A 6 4478 4032 4427 900 318 1001 C ATOM 779 C1' DC A 6 59.827 -53.362 3.987 1.00 33.51 C ANISOU 779 C1' DC A 6 4026 4075 4632 1074 358 903 C ATOM 780 N1 DC A 6 59.088 -53.644 2.718 1.00 33.65 N ANISOU 780 N1 DC A 6 3866 4444 4477 781 634 781 N ATOM 781 C2 DC A 6 59.370 -52.849 1.603 1.00 34.19 C ANISOU 781 C2 DC A 6 3448 4864 4679 965 739 795 C ATOM 782 O2 DC A 6 60.221 -51.955 1.727 1.00 32.07 O ANISOU 782 O2 DC A 6 2917 4523 4745 1278 673 902 O ATOM 783 N3 DC A 6 58.729 -53.092 0.426 1.00 33.02 N ANISOU 783 N3 DC A 6 3136 5113 4298 836 947 647 N ATOM 784 C4 DC A 6 57.819 -54.074 0.352 1.00 36.74 C ANISOU 784 C4 DC A 6 3818 5650 4490 455 1045 403 C ATOM 785 N4 DC A 6 57.216 -54.262 -0.827 1.00 36.34 N ANISOU 785 N4 DC A 6 3513 6081 4214 391 1205 149 N ATOM 786 C5 DC A 6 57.536 -54.902 1.468 1.00 36.59 C ANISOU 786 C5 DC A 6 4287 5190 4425 175 1031 372 C ATOM 787 C6 DC A 6 58.168 -54.653 2.632 1.00 35.80 C ANISOU 787 C6 DC A 6 4438 4692 4473 384 828 609 C ATOM 788 P DA A 7 60.979 -52.181 8.279 1.00 35.52 P ANISOU 788 P DA A 7 4722 3809 4965 2062 -579 1043 P ATOM 789 OP1 DA A 7 62.353 -51.588 8.290 1.00 41.20 O ANISOU 789 OP1 DA A 7 4922 4554 6176 2163 -755 743 O ATOM 790 OP2 DA A 7 60.834 -53.433 9.076 1.00 38.48 O ANISOU 790 OP2 DA A 7 5914 3764 4942 2201 -581 1118 O ATOM 791 O5' DA A 7 59.945 -51.078 8.733 1.00 38.25 O ANISOU 791 O5' DA A 7 4809 4504 5219 1786 -525 1193 O ATOM 792 C5' DA A 7 58.555 -51.415 8.966 1.00 33.38 C ANISOU 792 C5' DA A 7 4538 3951 4194 1338 -287 1357 C ATOM 793 C4' DA A 7 57.632 -50.435 8.286 1.00 29.80 C ANISOU 793 C4' DA A 7 3578 4000 3745 965 -91 1415 C ATOM 794 O4' DA A 7 57.622 -50.709 6.870 1.00 29.48 O ANISOU 794 O4' DA A 7 3310 4132 3760 809 136 1320 O ATOM 795 C3' DA A 7 56.172 -50.482 8.751 1.00 31.60 C ANISOU 795 C3' DA A 7 4016 4390 3600 535 88 1502 C ATOM 796 O3' DA A 7 56.112 -49.530 9.790 1.00 34.39 O ANISOU 796 O3' DA A 7 4263 4827 3976 695 -120 1626 O ATOM 797 C2' DA A 7 55.418 -50.026 7.498 1.00 31.53 C ANISOU 797 C2' DA A 7 3539 4901 3539 237 324 1431 C ATOM 798 C1' DA A 7 56.444 -50.130 6.362 1.00 27.70 C ANISOU 798 C1' DA A 7 2808 4393 3324 485 341 1348 C ATOM 799 N9 DA A 7 56.023 -50.965 5.233 1.00 29.49 N ANISOU 799 N9 DA A 7 3053 4761 3392 252 570 1161 N ATOM 800 C8 DA A 7 55.584 -52.273 5.299 1.00 31.42 C ANISOU 800 C8 DA A 7 3727 4749 3461 -50 719 986 C ATOM 801 N7 DA A 7 55.291 -52.782 4.107 1.00 32.63 N ANISOU 801 N7 DA A 7 3711 5148 3539 -209 907 741 N ATOM 802 C5 DA A 7 55.548 -51.757 3.223 1.00 30.54 C ANISOU 802 C5 DA A 7 2941 5324 3337 68 873 817 C ATOM 803 C6 DA A 7 55.393 -51.661 1.822 1.00 31.95 C ANISOU 803 C6 DA A 7 2776 5959 3404 167 1015 659 C ATOM 804 N6 DA A 7 54.955 -52.689 1.073 1.00 33.70 N ANISOU 804 N6 DA A 7 3039 6299 3466 -58 1152 305 N ATOM 805 N1 DA A 7 55.756 -50.493 1.213 1.00 35.59 N ANISOU 805 N1 DA A 7 2962 6605 3955 530 993 817 N ATOM 806 C2 DA A 7 56.186 -49.487 1.987 1.00 33.30 C ANISOU 806 C2 DA A 7 2706 6060 3886 663 848 1036 C ATOM 807 N3 DA A 7 56.324 -49.444 3.325 1.00 31.86 N ANISOU 807 N3 DA A 7 2536 5742 3829 623 781 1224 N ATOM 808 C4 DA A 7 56.005 -50.630 3.894 1.00 33.32 C ANISOU 808 C4 DA A 7 3143 5642 3874 328 719 1085 C ATOM 809 P DT A 8 54.872 -49.492 10.830 1.00 40.92 P ANISOU 809 P DT A 8 3908 6462 5176 -803 -1592 1755 P ATOM 810 OP1 DT A 8 55.432 -48.729 12.010 1.00 40.31 O ANISOU 810 OP1 DT A 8 3870 6642 4803 -1166 -1974 1823 O ATOM 811 OP2 DT A 8 54.357 -50.860 10.997 1.00 44.73 O ANISOU 811 OP2 DT A 8 4563 6752 5681 -622 -1612 1960 O ATOM 812 O5' DT A 8 53.710 -48.745 9.993 1.00 36.14 O ANISOU 812 O5' DT A 8 3526 5769 4438 -819 -1118 1381 O ATOM 813 C5' DT A 8 53.861 -47.358 9.803 1.00 31.28 C ANISOU 813 C5' DT A 8 2901 5252 3732 -1002 -1004 1150 C ATOM 814 C4' DT A 8 52.916 -46.832 8.749 1.00 27.11 C ANISOU 814 C4' DT A 8 2522 4575 3204 -885 -614 873 C ATOM 815 O4' DT A 8 53.247 -47.429 7.474 1.00 29.47 O ANISOU 815 O4' DT A 8 2641 4720 3835 -586 -445 890 O ATOM 816 C3' DT A 8 51.458 -47.164 8.944 1.00 29.41 C ANISOU 816 C3' DT A 8 3095 4784 3297 -877 -471 763 C ATOM 817 O3' DT A 8 50.914 -46.150 9.775 1.00 32.28 O ANISOU 817 O3' DT A 8 3677 5230 3358 -1152 -426 593 O ATOM 818 C2' DT A 8 50.909 -47.173 7.521 1.00 26.92 C ANISOU 818 C2' DT A 8 2770 4299 3160 -622 -216 604 C ATOM 819 C1' DT A 8 52.144 -47.260 6.617 1.00 26.79 C ANISOU 819 C1' DT A 8 2516 4241 3423 -474 -191 688 C ATOM 820 N1 DT A 8 52.174 -48.457 5.698 1.00 29.20 N ANISOU 820 N1 DT A 8 2754 4377 3962 -211 -82 747 N ATOM 821 C2 DT A 8 52.306 -48.272 4.328 1.00 32.99 C ANISOU 821 C2 DT A 8 3261 4720 4552 -68 159 619 C ATOM 822 O2 DT A 8 52.381 -47.179 3.795 1.00 29.69 O ANISOU 822 O2 DT A 8 2933 4299 4051 -128 277 490 O ATOM 823 N3 DT A 8 52.378 -49.425 3.591 1.00 29.80 N ANISOU 823 N3 DT A 8 2838 4149 4336 128 281 650 N ATOM 824 C4 DT A 8 52.272 -50.713 4.074 1.00 29.08 C ANISOU 824 C4 DT A 8 2703 3984 4364 216 190 798 C ATOM 825 O4 DT A 8 52.332 -51.724 3.351 1.00 30.02 O ANISOU 825 O4 DT A 8 2841 3900 4663 385 348 792 O ATOM 826 C5 DT A 8 52.147 -50.849 5.504 1.00 28.90 C ANISOU 826 C5 DT A 8 2664 4095 4221 76 -83 970 C ATOM 827 C7 DT A 8 52.047 -52.233 6.077 1.00 29.65 C ANISOU 827 C7 DT A 8 2792 4064 4412 156 -188 1178 C ATOM 828 C6 DT A 8 52.098 -49.727 6.248 1.00 26.56 C ANISOU 828 C6 DT A 8 2396 3995 3701 -142 -206 930 C ATOM 829 P DT A 9 49.646 -46.418 10.705 1.00 30.43 P ANISOU 829 P DT A 9 3720 4989 2854 -1316 -318 501 P ATOM 830 OP1 DT A 9 49.699 -45.370 11.762 1.00 36.97 O ANISOU 830 OP1 DT A 9 4757 5926 3365 -1664 -320 375 O ATOM 831 OP2 DT A 9 49.545 -47.829 11.146 1.00 30.12 O ANISOU 831 OP2 DT A 9 3728 4921 2794 -1289 -438 734 O ATOM 832 O5' DT A 9 48.385 -46.129 9.766 1.00 26.85 O ANISOU 832 O5' DT A 9 3267 4387 2548 -1118 -19 235 O ATOM 833 C5' DT A 9 48.266 -44.867 9.116 1.00 26.43 C ANISOU 833 C5' DT A 9 3214 4271 2559 -1051 111 34 C ATOM 834 C4' DT A 9 46.981 -44.941 8.302 1.00 24.95 C ANISOU 834 C4' DT A 9 2999 3950 2531 -827 272 -143 C ATOM 835 O4' DT A 9 47.124 -45.936 7.258 1.00 28.04 O ANISOU 835 O4' DT A 9 3277 4281 3097 -599 198 -28 O ATOM 836 C3' DT A 9 45.741 -45.328 9.089 1.00 28.11 C ANISOU 836 C3' DT A 9 3444 4355 2880 -942 423 -284 C ATOM 837 O3' DT A 9 44.686 -44.490 8.607 1.00 27.83 O ANISOU 837 O3' DT A 9 3357 4213 3006 -798 578 -540 O ATOM 838 C2' DT A 9 45.519 -46.803 8.740 1.00 26.03 C ANISOU 838 C2' DT A 9 3099 4071 2722 -849 360 -153 C ATOM 839 C1' DT A 9 46.078 -46.897 7.322 1.00 23.13 C ANISOU 839 C1' DT A 9 2629 3628 2533 -574 250 -82 C ATOM 840 N1 DT A 9 46.758 -48.155 7.002 1.00 23.73 N ANISOU 840 N1 DT A 9 2661 3669 2686 -496 154 129 N ATOM 841 C2 DT A 9 46.621 -48.700 5.736 1.00 27.46 C ANISOU 841 C2 DT A 9 3093 4024 3315 -288 165 98 C ATOM 842 O2 DT A 9 45.889 -48.225 4.895 1.00 25.26 O ANISOU 842 O2 DT A 9 2823 3697 3079 -178 187 -75 O ATOM 843 N3 DT A 9 47.315 -49.860 5.514 1.00 24.55 N ANISOU 843 N3 DT A 9 2700 3578 3049 -216 138 274 N ATOM 844 C4 DT A 9 48.141 -50.492 6.416 1.00 26.56 C ANISOU 844 C4 DT A 9 2931 3857 3302 -285 43 516 C ATOM 845 O4 DT A 9 48.760 -51.510 6.145 1.00 26.86 O ANISOU 845 O4 DT A 9 2926 3775 3504 -161 25 676 O ATOM 846 C5 DT A 9 48.275 -49.856 7.706 1.00 24.71 C ANISOU 846 C5 DT A 9 2751 3779 2860 -510 -51 575 C ATOM 847 C7 DT A 9 49.162 -50.493 8.731 1.00 27.49 C ANISOU 847 C7 DT A 9 3117 4174 3153 -600 -262 876 C ATOM 848 C6 DT A 9 47.593 -48.727 7.944 1.00 26.01 C ANISOU 848 C6 DT A 9 2974 4020 2887 -627 37 362 C ATOM 849 P DG A 10 43.235 -44.470 9.293 1.00 29.71 P ANISOU 849 P DG A 10 3543 4424 3322 -887 840 -801 P ATOM 850 OP1 DG A 10 42.791 -43.038 9.162 1.00 28.93 O ANISOU 850 OP1 DG A 10 3447 4201 3343 -780 978 -1024 O ATOM 851 OP2 DG A 10 43.265 -45.042 10.666 1.00 27.74 O ANISOU 851 OP2 DG A 10 3467 4268 2805 -1241 970 -767 O ATOM 852 O5' DG A 10 42.372 -45.370 8.342 1.00 27.87 O ANISOU 852 O5' DG A 10 3082 4153 3355 -674 771 -835 O ATOM 853 C5' DG A 10 42.361 -45.059 6.959 1.00 27.82 C ANISOU 853 C5' DG A 10 2990 4065 3517 -366 579 -822 C ATOM 854 C4' DG A 10 41.720 -46.208 6.215 1.00 30.78 C ANISOU 854 C4' DG A 10 3210 4438 4046 -276 473 -832 C ATOM 855 O4' DG A 10 42.645 -47.322 6.168 1.00 28.73 O ANISOU 855 O4' DG A 10 3062 4203 3651 -353 404 -605 O ATOM 856 C3' DG A 10 40.432 -46.724 6.817 1.00 36.10 C ANISOU 856 C3' DG A 10 3681 5139 4895 -409 654 -1042 C ATOM 857 O3' DG A 10 39.526 -46.718 5.708 1.00 39.67 O ANISOU 857 O3' DG A 10 3901 5552 5619 -184 473 -1178 O ATOM 858 C2' DG A 10 40.817 -48.118 7.335 1.00 29.21 C ANISOU 858 C2' DG A 10 2925 4300 3872 -633 707 -882 C ATOM 859 C1' DG A 10 41.874 -48.523 6.324 1.00 31.54 C ANISOU 859 C1' DG A 10 3330 4555 4100 -460 468 -661 C ATOM 860 N9 DG A 10 42.873 -49.506 6.751 1.00 26.99 N ANISOU 860 N9 DG A 10 2915 3966 3374 -567 452 -405 N ATOM 861 C8 DG A 10 43.518 -49.594 7.973 1.00 28.65 C ANISOU 861 C8 DG A 10 3277 4230 3377 -767 497 -238 C ATOM 862 N7 DG A 10 44.408 -50.559 8.007 1.00 30.37 N ANISOU 862 N7 DG A 10 3585 4396 3559 -752 391 20 N ATOM 863 C5 DG A 10 44.351 -51.138 6.731 1.00 23.85 C ANISOU 863 C5 DG A 10 2680 3461 2923 -548 347 -15 C ATOM 864 C6 DG A 10 45.068 -52.232 6.192 1.00 26.78 C ANISOU 864 C6 DG A 10 3097 3691 3386 -433 301 157 C ATOM 865 O6 DG A 10 45.939 -52.891 6.765 1.00 26.14 O ANISOU 865 O6 DG A 10 3086 3556 3290 -441 245 416 O ATOM 866 N1 DG A 10 44.709 -52.500 4.857 1.00 24.77 N ANISOU 866 N1 DG A 10 2813 3340 3258 -289 309 2 N ATOM 867 C2 DG A 10 43.755 -51.790 4.173 1.00 26.56 C ANISOU 867 C2 DG A 10 2961 3624 3507 -253 273 -244 C ATOM 868 N2 DG A 10 43.519 -52.175 2.908 1.00 26.82 N ANISOU 868 N2 DG A 10 3037 3561 3591 -151 220 -355 N ATOM 869 N3 DG A 10 43.065 -50.759 4.676 1.00 24.76 N ANISOU 869 N3 DG A 10 2632 3516 3260 -305 278 -378 N ATOM 870 C4 DG A 10 43.418 -50.497 5.955 1.00 28.31 C ANISOU 870 C4 DG A 10 3125 4041 3592 -458 358 -270 C ATOM 871 P DT A 11 38.001 -47.182 5.867 1.00 39.75 P ANISOU 871 P DT A 11 3541 5592 5970 -252 579 -1454 P ATOM 872 OP1 DT A 11 37.178 -46.316 4.973 1.00 46.52 O ANISOU 872 OP1 DT A 11 4139 6403 7134 57 343 -1600 O ATOM 873 OP2 DT A 11 37.619 -47.389 7.269 1.00 35.06 O ANISOU 873 OP2 DT A 11 2928 5032 5361 -559 984 -1576 O ATOM 874 O5' DT A 11 37.962 -48.588 5.152 1.00 33.39 O ANISOU 874 O5' DT A 11 2738 4796 5151 -324 420 -1393 O ATOM 875 C5' DT A 11 38.276 -48.590 3.791 1.00 32.13 C ANISOU 875 C5' DT A 11 2666 4597 4944 -104 77 -1307 C ATOM 876 C4' DT A 11 38.214 -50.012 3.289 1.00 30.14 C ANISOU 876 C4' DT A 11 2460 4324 4668 -244 21 -1300 C ATOM 877 O4' DT A 11 39.324 -50.743 3.855 1.00 30.19 O ANISOU 877 O4' DT A 11 2749 4278 4445 -376 198 -1075 O ATOM 878 C3' DT A 11 36.961 -50.774 3.673 1.00 39.92 C ANISOU 878 C3' DT A 11 3386 5604 6179 -468 145 -1542 C ATOM 879 O3' DT A 11 36.523 -51.265 2.431 1.00 42.59 O ANISOU 879 O3' DT A 11 3665 5932 6586 -415 -170 -1636 O ATOM 880 C2' DT A 11 37.440 -51.874 4.616 1.00 33.87 C ANISOU 880 C2' DT A 11 2835 4776 5258 -755 455 -1419 C ATOM 881 C1' DT A 11 38.892 -52.035 4.207 1.00 27.38 C ANISOU 881 C1' DT A 11 2377 3874 4152 -617 348 -1124 C ATOM 882 N1 DT A 11 39.855 -52.515 5.238 1.00 28.80 N ANISOU 882 N1 DT A 11 2808 4000 4133 -746 539 -874 N ATOM 883 C2 DT A 11 40.709 -53.535 4.865 1.00 27.65 C ANISOU 883 C2 DT A 11 2884 3713 3909 -720 512 -682 C ATOM 884 O2 DT A 11 40.682 -54.047 3.751 1.00 29.80 O ANISOU 884 O2 DT A 11 3190 3896 4235 -637 404 -748 O ATOM 885 N3 DT A 11 41.600 -53.939 5.827 1.00 27.98 N ANISOU 885 N3 DT A 11 3123 3700 3807 -793 604 -413 N ATOM 886 C4 DT A 11 41.700 -53.420 7.105 1.00 29.12 C ANISOU 886 C4 DT A 11 3324 3941 3800 -941 700 -330 C ATOM 887 O4 DT A 11 42.483 -53.854 7.946 1.00 32.84 O ANISOU 887 O4 DT A 11 4003 4365 4108 -1021 702 -63 O ATOM 888 C5 DT A 11 40.753 -52.375 7.439 1.00 32.64 C ANISOU 888 C5 DT A 11 3583 4525 4295 -1011 801 -586 C ATOM 889 C7 DT A 11 40.830 -51.764 8.803 1.00 31.92 C ANISOU 889 C7 DT A 11 3616 4516 3996 -1216 968 -555 C ATOM 890 C6 DT A 11 39.894 -51.945 6.506 1.00 29.54 C ANISOU 890 C6 DT A 11 2931 4167 4125 -881 722 -839 C ATOM 891 P DC A 12 35.088 -51.947 2.256 1.00 50.29 P ANISOU 891 P DC A 12 4228 6970 7910 -610 -228 -1944 P ATOM 892 OP1 DC A 12 34.786 -51.594 0.837 1.00 48.49 O ANISOU 892 OP1 DC A 12 3964 6771 7688 -396 -740 -1992 O ATOM 893 OP2 DC A 12 34.130 -51.611 3.323 1.00 52.75 O ANISOU 893 OP2 DC A 12 4209 7330 8506 -708 70 -2109 O ATOM 894 O5' DC A 12 35.389 -53.518 2.398 1.00 43.81 O ANISOU 894 O5' DC A 12 3653 6033 6959 -927 -15 -1909 O ATOM 895 C5' DC A 12 36.123 -54.129 1.373 1.00 35.89 C ANISOU 895 C5' DC A 12 3005 4919 5714 -874 -197 -1798 C ATOM 896 C4' DC A 12 36.714 -55.446 1.824 1.00 35.99 C ANISOU 896 C4' DC A 12 3318 4745 5613 -1098 110 -1682 C ATOM 897 O4' DC A 12 37.645 -55.218 2.916 1.00 33.12 O ANISOU 897 O4' DC A 12 3134 4344 5104 -1050 359 -1413 O ATOM 898 C3' DC A 12 35.716 -56.452 2.368 1.00 37.70 C ANISOU 898 C3' DC A 12 3359 4916 6049 -1473 339 -1889 C ATOM 899 O3' DC A 12 35.364 -57.329 1.316 1.00 39.86 O ANISOU 899 O3' DC A 12 3698 5101 6345 -1612 171 -2064 O ATOM 900 C2' DC A 12 36.506 -57.216 3.417 1.00 41.14 C ANISOU 900 C2' DC A 12 4134 5164 6334 -1604 706 -1635 C ATOM 901 C1' DC A 12 37.831 -56.488 3.516 1.00 39.02 C ANISOU 901 C1' DC A 12 4092 4906 5829 -1288 627 -1324 C ATOM 902 N1 DC A 12 38.313 -56.235 4.921 1.00 31.03 N ANISOU 902 N1 DC A 12 3188 3906 4695 -1346 854 -1104 N ATOM 903 C2 DC A 12 39.451 -56.924 5.366 1.00 35.60 C ANISOU 903 C2 DC A 12 4115 4306 5106 -1314 932 -778 C ATOM 904 O2 DC A 12 40.000 -57.716 4.580 1.00 33.59 O ANISOU 904 O2 DC A 12 4033 3862 4867 -1217 882 -710 O ATOM 905 N3 DC A 12 39.919 -56.698 6.632 1.00 31.78 N ANISOU 905 N3 DC A 12 3775 3848 4453 -1388 1047 -553 N ATOM 906 C4 DC A 12 39.271 -55.840 7.424 1.00 34.94 C ANISOU 906 C4 DC A 12 4027 4425 4824 -1523 1166 -687 C ATOM 907 N4 DC A 12 39.742 -55.666 8.665 1.00 36.52 N ANISOU 907 N4 DC A 12 4454 4641 4779 -1652 1277 -479 N ATOM 908 C5 DC A 12 38.082 -55.151 6.994 1.00 35.54 C ANISOU 908 C5 DC A 12 3717 4652 5136 -1539 1175 -1049 C ATOM 909 C6 DC A 12 37.650 -55.366 5.744 1.00 33.03 C ANISOU 909 C6 DC A 12 3217 4327 5008 -1430 974 -1226 C ATOM 910 P DT A 13 34.350 -58.546 1.570 1.00 45.85 P ANISOU 910 P DT A 13 5016 6533 5873 -2585 -165 140 P ATOM 911 OP1 DT A 13 33.684 -58.804 0.269 1.00 47.28 O ANISOU 911 OP1 DT A 13 5423 6680 5861 -2917 -464 267 O ATOM 912 OP2 DT A 13 33.524 -58.316 2.788 1.00 40.64 O ANISOU 912 OP2 DT A 13 4076 5720 5644 -2341 -52 273 O ATOM 913 O5' DT A 13 35.293 -59.788 1.949 1.00 40.11 O ANISOU 913 O5' DT A 13 4691 5773 4778 -2791 10 -152 O ATOM 914 C5' DT A 13 36.305 -60.247 1.051 1.00 47.16 C ANISOU 914 C5' DT A 13 6065 6637 5217 -2659 91 -393 C ATOM 915 C4' DT A 13 37.073 -61.379 1.698 1.00 45.20 C ANISOU 915 C4' DT A 13 6223 6187 4765 -2264 394 -569 C ATOM 916 O4' DT A 13 37.828 -60.834 2.809 1.00 39.01 O ANISOU 916 O4' DT A 13 4990 5691 4141 -1842 642 -556 O ATOM 917 C3' DT A 13 36.189 -62.450 2.324 1.00 47.46 C ANISOU 917 C3' DT A 13 6760 6122 5150 -2451 340 -505 C ATOM 918 O3' DT A 13 35.989 -63.522 1.424 1.00 60.28 O ANISOU 918 O3' DT A 13 9113 7356 6435 -2719 262 -631 O ATOM 919 C2' DT A 13 36.965 -62.939 3.533 1.00 45.97 C ANISOU 919 C2' DT A 13 6522 5954 4989 -1936 691 -540 C ATOM 920 C1' DT A 13 37.971 -61.841 3.800 1.00 40.16 C ANISOU 920 C1' DT A 13 5312 5670 4276 -1600 840 -556 C ATOM 921 N1 DT A 13 37.849 -61.104 5.081 1.00 35.10 N ANISOU 921 N1 DT A 13 4114 5299 3925 -1513 901 -454 N ATOM 922 C2 DT A 13 38.847 -61.283 6.019 1.00 34.03 C ANISOU 922 C2 DT A 13 3858 5385 3684 -1113 1155 -452 C ATOM 923 O2 DT A 13 39.748 -62.073 5.825 1.00 37.95 O ANISOU 923 O2 DT A 13 4645 5845 3930 -790 1346 -465 O ATOM 924 N3 DT A 13 38.727 -60.522 7.160 1.00 31.38 N ANISOU 924 N3 DT A 13 3078 5310 3535 -1123 1200 -398 N ATOM 925 C4 DT A 13 37.728 -59.613 7.428 1.00 33.83 C ANISOU 925 C4 DT A 13 3087 5610 4156 -1418 1101 -354 C ATOM 926 O4 DT A 13 37.689 -58.958 8.471 1.00 34.75 O ANISOU 926 O4 DT A 13 3081 5724 4398 -1238 1082 -293 O ATOM 927 C5 DT A 13 36.727 -59.473 6.395 1.00 36.31 C ANISOU 927 C5 DT A 13 3470 5689 4636 -1753 871 -282 C ATOM 928 C7 DT A 13 35.601 -58.508 6.562 1.00 35.96 C ANISOU 928 C7 DT A 13 3265 5420 4978 -1687 681 -57 C ATOM 929 C6 DT A 13 36.834 -60.205 5.272 1.00 36.70 C ANISOU 929 C6 DT A 13 3932 5550 4461 -1823 740 -334 C ATOM 930 P DG A 14 34.984 -64.726 1.795 1.00 71.00 P ANISOU 930 P DG A 14 10859 8271 7846 -3065 145 -566 P ATOM 931 OP1 DG A 14 34.715 -65.429 0.523 1.00 79.97 O ANISOU 931 OP1 DG A 14 12744 9075 8565 -3540 -32 -719 O ATOM 932 OP2 DG A 14 33.864 -64.245 2.652 1.00 56.88 O ANISOU 932 OP2 DG A 14 8453 6628 6533 -3293 -69 -252 O ATOM 933 O5' DG A 14 35.849 -65.677 2.733 1.00 58.16 O ANISOU 933 O5' DG A 14 9485 6440 6173 -2484 602 -667 O ATOM 934 C5' DG A 14 37.112 -66.154 2.320 1.00 61.87 C ANISOU 934 C5' DG A 14 10404 6800 6305 -2023 990 -859 C ATOM 935 C4' DG A 14 37.560 -67.098 3.414 1.00 61.35 C ANISOU 935 C4' DG A 14 10435 6549 6326 -1559 1366 -786 C ATOM 936 O4' DG A 14 37.841 -66.373 4.631 1.00 54.39 O ANISOU 936 O4' DG A 14 8793 6142 5731 -1243 1412 -600 O ATOM 937 C3' DG A 14 36.539 -68.153 3.813 1.00 58.52 C ANISOU 937 C3' DG A 14 10429 5722 6086 -1893 1276 -731 C ATOM 938 O3' DG A 14 37.279 -69.315 4.032 1.00 57.95 O ANISOU 938 O3' DG A 14 10887 5264 5866 -1455 1748 -773 O ATOM 939 C2' DG A 14 35.903 -67.662 5.114 1.00 52.49 C ANISOU 939 C2' DG A 14 8932 5267 5746 -1893 1132 -477 C ATOM 940 C1' DG A 14 37.023 -66.813 5.701 1.00 51.09 C ANISOU 940 C1' DG A 14 8210 5614 5588 -1349 1355 -439 C ATOM 941 N9 DG A 14 36.581 -65.577 6.324 1.00 48.82 N ANISOU 941 N9 DG A 14 7203 5768 5579 -1471 1151 -323 N ATOM 942 C8 DG A 14 35.553 -64.750 5.940 1.00 46.92 C ANISOU 942 C8 DG A 14 6685 5604 5539 -1939 812 -259 C ATOM 943 N7 DG A 14 35.433 -63.685 6.691 1.00 38.03 N ANISOU 943 N7 DG A 14 4957 4836 4656 -1876 815 -159 N ATOM 944 C5 DG A 14 36.447 -63.816 7.635 1.00 40.14 C ANISOU 944 C5 DG A 14 5108 5320 4824 -1410 1110 -183 C ATOM 945 C6 DG A 14 36.804 -62.980 8.713 1.00 36.72 C ANISOU 945 C6 DG A 14 4188 5285 4480 -1229 1236 -139 C ATOM 946 O6 DG A 14 36.274 -61.909 9.072 1.00 43.00 O ANISOU 946 O6 DG A 14 4594 6251 5494 -1404 1181 -105 O ATOM 947 N1 DG A 14 37.885 -63.499 9.429 1.00 34.89 N ANISOU 947 N1 DG A 14 3971 5245 4042 -820 1480 -106 N ATOM 948 C2 DG A 14 38.542 -64.663 9.118 1.00 44.78 C ANISOU 948 C2 DG A 14 5629 6290 5095 -533 1653 -79 C ATOM 949 N2 DG A 14 39.574 -65.000 9.907 1.00 48.86 N ANISOU 949 N2 DG A 14 6007 7091 5466 -122 1897 71 N ATOM 950 N3 DG A 14 38.217 -65.455 8.101 1.00 52.98 N ANISOU 950 N3 DG A 14 7200 6865 6064 -656 1618 -166 N ATOM 951 C4 DG A 14 37.163 -64.969 7.412 1.00 47.32 C ANISOU 951 C4 DG A 14 6496 5999 5484 -1137 1310 -235 C ATOM 952 P DG A 15 36.528 -70.682 4.365 1.00 86.20 P ANISOU 952 P DG A 15 15035 8212 9504 -1690 1816 -748 P ATOM 953 OP1 DG A 15 37.310 -71.781 3.749 1.00 88.11 O ANISOU 953 OP1 DG A 15 16170 7885 9422 -1399 2321 -928 O ATOM 954 OP2 DG A 15 35.109 -70.489 3.983 1.00 85.51 O ANISOU 954 OP2 DG A 15 14942 8044 9504 -2505 1260 -733 O ATOM 955 O5' DG A 15 36.632 -70.769 5.955 1.00 63.24 O ANISOU 955 O5' DG A 15 11509 5564 6954 -1256 1977 -445 O ATOM 956 C5' DG A 15 37.906 -70.730 6.556 1.00 57.68 C ANISOU 956 C5' DG A 15 10532 5159 6225 -534 2396 -312 C ATOM 957 C4' DG A 15 37.731 -70.587 8.055 1.00 59.46 C ANISOU 957 C4' DG A 15 10099 5746 6748 -340 2385 -21 C ATOM 958 O4' DG A 15 37.217 -69.269 8.339 1.00 60.10 O ANISOU 958 O4' DG A 15 9518 6336 6982 -621 2004 -16 O ATOM 959 C3' DG A 15 36.776 -71.549 8.764 1.00 62.53 C ANISOU 959 C3' DG A 15 10661 5736 7360 -537 2367 128 C ATOM 960 O3' DG A 15 37.464 -71.949 9.944 1.00 65.87 O ANISOU 960 O3' DG A 15 10776 6380 7871 22 2707 419 O ATOM 961 C2' DG A 15 35.548 -70.692 9.087 1.00 56.80 C ANISOU 961 C2' DG A 15 9434 5265 6883 -1058 1891 179 C ATOM 962 C1' DG A 15 36.230 -69.360 9.357 1.00 48.89 C ANISOU 962 C1' DG A 15 7792 4931 5851 -821 1859 170 C ATOM 963 N9 DG A 15 35.401 -68.159 9.246 1.00 47.97 N ANISOU 963 N9 DG A 15 7225 5096 5906 -1231 1495 152 N ATOM 964 C8 DG A 15 34.430 -67.844 8.315 1.00 51.74 C ANISOU 964 C8 DG A 15 7811 5401 6448 -1784 1142 98 C ATOM 965 N7 DG A 15 33.901 -66.661 8.487 1.00 43.37 N ANISOU 965 N7 DG A 15 6198 4684 5597 -1966 949 184 N ATOM 966 C5 DG A 15 34.572 -66.168 9.598 1.00 42.82 C ANISOU 966 C5 DG A 15 5713 5000 5558 -1548 1188 223 C ATOM 967 C6 DG A 15 34.427 -64.933 10.266 1.00 42.50 C ANISOU 967 C6 DG A 15 5109 5357 5682 -1535 1193 274 C ATOM 968 O6 DG A 15 33.644 -64.022 9.960 1.00 39.97 O ANISOU 968 O6 DG A 15 4510 5095 5581 -1831 1024 338 O ATOM 969 N1 DG A 15 35.303 -64.817 11.354 1.00 40.20 N ANISOU 969 N1 DG A 15 4608 5399 5268 -1153 1446 279 N ATOM 970 C2 DG A 15 36.203 -65.785 11.740 1.00 45.77 C ANISOU 970 C2 DG A 15 5521 6105 5763 -785 1658 323 C ATOM 971 N2 DG A 15 36.965 -65.514 12.813 1.00 38.69 N ANISOU 971 N2 DG A 15 4319 5642 4739 -509 1833 402 N ATOM 972 N3 DG A 15 36.348 -66.951 11.115 1.00 41.22 N ANISOU 972 N3 DG A 15 5443 5122 5097 -709 1720 318 N ATOM 973 C4 DG A 15 35.503 -67.063 10.064 1.00 42.24 C ANISOU 973 C4 DG A 15 5870 4879 5299 -1122 1481 225 C ATOM 974 P DG A 16 36.876 -73.077 10.928 1.00 74.68 P ANISOU 974 P DG A 16 12001 7157 9217 67 2857 680 P ATOM 975 OP1 DG A 16 37.976 -74.036 11.178 1.00 78.67 O ANISOU 975 OP1 DG A 16 12754 7493 9645 710 3413 890 O ATOM 976 OP2 DG A 16 35.591 -73.587 10.400 1.00 76.57 O ANISOU 976 OP2 DG A 16 12705 6827 9560 -567 2584 552 O ATOM 977 O5' DG A 16 36.580 -72.269 12.281 1.00 71.62 O ANISOU 977 O5' DG A 16 10778 7422 9013 97 2678 912 O ATOM 978 C5' DG A 16 37.644 -71.629 12.995 1.00 65.11 C ANISOU 978 C5' DG A 16 9413 7263 8064 530 2819 1065 C ATOM 979 C4' DG A 16 37.143 -70.887 14.230 1.00 54.83 C ANISOU 979 C4' DG A 16 7488 6468 6878 407 2643 1206 C ATOM 980 O4' DG A 16 36.528 -69.629 13.835 1.00 50.82 O ANISOU 980 O4' DG A 16 6744 6146 6419 -7 2313 966 O ATOM 981 C3' DG A 16 36.119 -71.632 15.085 1.00 58.60 C ANISOU 981 C3' DG A 16 7974 6688 7604 279 2647 1424 C ATOM 982 O3' DG A 16 36.492 -71.604 16.454 1.00 63.84 O ANISOU 982 O3' DG A 16 8193 7842 8222 564 2796 1718 O ATOM 983 C2' DG A 16 34.832 -70.839 14.906 1.00 52.91 C ANISOU 983 C2' DG A 16 7094 5925 7085 -256 2297 1292 C ATOM 984 C1' DG A 16 35.344 -69.444 14.584 1.00 52.01 C ANISOU 984 C1' DG A 16 6660 6285 6817 -292 2173 1075 C ATOM 985 N9 DG A 16 34.395 -68.726 13.746 1.00 45.41 N ANISOU 985 N9 DG A 16 5825 5290 6139 -760 1872 914 N ATOM 986 C8 DG A 16 33.785 -69.224 12.620 1.00 46.33 C ANISOU 986 C8 DG A 16 6370 4919 6315 -1104 1684 827 C ATOM 987 N7 DG A 16 32.972 -68.373 12.066 1.00 46.20 N ANISOU 987 N7 DG A 16 6170 4942 6443 -1509 1402 790 N ATOM 988 C5 DG A 16 33.025 -67.247 12.874 1.00 41.99 C ANISOU 988 C5 DG A 16 5097 4873 5986 -1388 1468 828 C ATOM 989 C6 DG A 16 32.348 -66.007 12.764 1.00 42.62 C ANISOU 989 C6 DG A 16 4789 5141 6266 -1633 1337 853 C ATOM 990 O6 DG A 16 31.539 -65.622 11.900 1.00 46.20 O ANISOU 990 O6 DG A 16 5204 5457 6892 -2009 1089 913 O ATOM 991 N1 DG A 16 32.706 -65.143 13.789 1.00 43.04 N ANISOU 991 N1 DG A 16 4475 5588 6290 -1415 1548 834 N ATOM 992 C2 DG A 16 33.593 -65.446 14.797 1.00 46.21 C ANISOU 992 C2 DG A 16 4847 6254 6457 -1070 1775 825 C ATOM 993 N2 DG A 16 33.790 -64.478 15.708 1.00 46.03 N ANISOU 993 N2 DG A 16 4516 6607 6366 -1010 1932 783 N ATOM 994 N3 DG A 16 34.236 -66.603 14.909 1.00 42.36 N ANISOU 994 N3 DG A 16 4623 5668 5803 -821 1866 883 N ATOM 995 C4 DG A 16 33.911 -67.452 13.912 1.00 47.95 C ANISOU 995 C4 DG A 16 5733 5911 6575 -968 1738 869 C TER 996 DG A 16 ATOM 997 O5' DG B 0 23.127 -59.214 13.658 1.00 61.85 O ANISOU 997 O5' DG B 0 6962 7600 8940 -911 -1114 -77 O ATOM 998 C5' DG B 0 24.054 -58.352 13.025 1.00 66.47 C ANISOU 998 C5' DG B 0 7708 8209 9338 -1037 -1311 194 C ATOM 999 C4' DG B 0 25.427 -58.586 13.618 1.00 67.68 C ANISOU 999 C4' DG B 0 7887 8441 9385 -950 -934 250 C ATOM 1000 O4' DG B 0 25.716 -60.012 13.641 1.00 64.17 O ANISOU 1000 O4' DG B 0 7494 8087 8801 -945 -447 124 O ATOM 1001 C3' DG B 0 26.575 -57.938 12.859 1.00 69.47 C ANISOU 1001 C3' DG B 0 8297 8724 9373 -1152 -994 467 C ATOM 1002 O3' DG B 0 27.584 -57.692 13.796 1.00 68.51 O ANISOU 1002 O3' DG B 0 8056 8651 9323 -977 -798 454 O ATOM 1003 C2' DG B 0 27.007 -59.064 11.940 1.00 67.12 C ANISOU 1003 C2' DG B 0 8179 8580 8743 -1372 -671 420 C ATOM 1004 C1' DG B 0 26.932 -60.199 12.950 1.00 61.79 C ANISOU 1004 C1' DG B 0 7357 7903 8217 -1114 -258 227 C ATOM 1005 N9 DG B 0 26.969 -61.506 12.315 1.00 53.47 N ANISOU 1005 N9 DG B 0 6400 6906 7009 -1257 115 87 N ATOM 1006 C8 DG B 0 26.427 -61.877 11.107 1.00 55.47 C ANISOU 1006 C8 DG B 0 6772 7228 7076 -1568 56 -6 C ATOM 1007 N7 DG B 0 26.648 -63.128 10.799 1.00 54.68 N ANISOU 1007 N7 DG B 0 6702 7157 6916 -1657 506 -195 N ATOM 1008 C5 DG B 0 27.397 -63.604 11.871 1.00 54.91 C ANISOU 1008 C5 DG B 0 6651 7103 7109 -1349 864 -163 C ATOM 1009 C6 DG B 0 27.936 -64.888 12.102 1.00 52.76 C ANISOU 1009 C6 DG B 0 6369 6765 6910 -1248 1413 -273 C ATOM 1010 O6 DG B 0 27.841 -65.882 11.368 1.00 54.57 O ANISOU 1010 O6 DG B 0 6649 6972 7113 -1453 1734 -479 O ATOM 1011 N1 DG B 0 28.635 -64.946 13.314 1.00 46.18 N ANISOU 1011 N1 DG B 0 5442 5899 6207 -865 1578 -132 N ATOM 1012 C2 DG B 0 28.781 -63.888 14.195 1.00 44.79 C ANISOU 1012 C2 DG B 0 5163 5790 6066 -650 1267 23 C ATOM 1013 N2 DG B 0 29.479 -64.112 15.323 1.00 38.37 N ANISOU 1013 N2 DG B 0 4236 5024 5317 -287 1463 119 N ATOM 1014 N3 DG B 0 28.277 -62.681 13.989 1.00 43.51 N ANISOU 1014 N3 DG B 0 4991 5652 5888 -773 796 73 N ATOM 1015 C4 DG B 0 27.606 -62.615 12.810 1.00 50.25 C ANISOU 1015 C4 DG B 0 5964 6498 6630 -1105 613 5 C ATOM 1016 P DC B 1 28.602 -56.468 13.597 1.00 70.12 P ANISOU 1016 P DC B 1 8304 8833 9507 -1100 -937 605 P ATOM 1017 OP1 DC B 1 27.850 -55.217 13.818 1.00 75.33 O ANISOU 1017 OP1 DC B 1 8870 9267 10486 -1054 -1359 671 O ATOM 1018 OP2 DC B 1 29.375 -56.691 12.347 1.00 75.45 O ANISOU 1018 OP2 DC B 1 9242 9603 9821 -1428 -818 728 O ATOM 1019 O5' DC B 1 29.601 -56.643 14.820 1.00 47.96 O ANISOU 1019 O5' DC B 1 5273 6190 6759 -848 -633 456 O ATOM 1020 C5' DC B 1 29.068 -57.033 16.083 1.00 47.06 C ANISOU 1020 C5' DC B 1 4927 6124 6829 -526 -550 304 C ATOM 1021 C4' DC B 1 30.084 -57.882 16.826 1.00 43.09 C ANISOU 1021 C4' DC B 1 4323 5871 6178 -307 -160 235 C ATOM 1022 O4' DC B 1 30.075 -59.226 16.277 1.00 41.96 O ANISOU 1022 O4' DC B 1 4347 5733 5864 -337 141 264 O ATOM 1023 C3' DC B 1 31.537 -57.425 16.768 1.00 40.58 C ANISOU 1023 C3' DC B 1 3950 5726 5740 -361 -62 217 C ATOM 1024 O3' DC B 1 32.110 -57.766 17.988 1.00 39.40 O ANISOU 1024 O3' DC B 1 3557 5837 5578 -28 124 109 O ATOM 1025 C2' DC B 1 32.167 -58.299 15.687 1.00 43.46 C ANISOU 1025 C2' DC B 1 4536 6125 5852 -556 189 277 C ATOM 1026 C1' DC B 1 31.377 -59.592 15.873 1.00 39.50 C ANISOU 1026 C1' DC B 1 4084 5569 5355 -395 389 274 C ATOM 1027 N1 DC B 1 31.260 -60.409 14.613 1.00 39.14 N ANISOU 1027 N1 DC B 1 4275 5449 5149 -670 546 287 N ATOM 1028 C2 DC B 1 31.640 -61.764 14.644 1.00 43.89 C ANISOU 1028 C2 DC B 1 4890 6080 5705 -550 966 228 C ATOM 1029 O2 DC B 1 32.059 -62.239 15.705 1.00 42.31 O ANISOU 1029 O2 DC B 1 4535 5962 5576 -189 1166 237 O ATOM 1030 N3 DC B 1 31.540 -62.515 13.509 1.00 39.59 N ANISOU 1030 N3 DC B 1 4518 5481 5043 -829 1148 161 N ATOM 1031 C4 DC B 1 31.089 -61.953 12.382 1.00 43.81 C ANISOU 1031 C4 DC B 1 5216 6002 5428 -1209 893 178 C ATOM 1032 N4 DC B 1 30.999 -62.735 11.292 1.00 45.07 N ANISOU 1032 N4 DC B 1 5514 6182 5428 -1499 1089 62 N ATOM 1033 C5 DC B 1 30.696 -60.575 12.326 1.00 43.42 C ANISOU 1033 C5 DC B 1 5187 5917 5395 -1301 433 315 C ATOM 1034 C6 DC B 1 30.793 -59.840 13.458 1.00 39.98 C ANISOU 1034 C6 DC B 1 4568 5467 5156 -1027 288 352 C ATOM 1035 P DC B 2 33.638 -57.403 18.302 1.00 41.34 P ANISOU 1035 P DC B 2 3613 6372 5722 24 247 -10 P ATOM 1036 OP1 DC B 2 33.677 -57.217 19.772 1.00 37.20 O ANISOU 1036 OP1 DC B 2 2767 6115 5253 365 231 -148 O ATOM 1037 OP2 DC B 2 34.130 -56.361 17.365 1.00 40.85 O ANISOU 1037 OP2 DC B 2 3649 6183 5688 -348 117 -15 O ATOM 1038 O5' DC B 2 34.460 -58.741 17.963 1.00 38.33 O ANISOU 1038 O5' DC B 2 3314 6125 5126 124 605 35 O ATOM 1039 C5' DC B 2 34.337 -59.831 18.888 1.00 37.59 C ANISOU 1039 C5' DC B 2 3133 6158 4990 523 813 88 C ATOM 1040 C4' DC B 2 35.351 -60.917 18.586 1.00 44.24 C ANISOU 1040 C4' DC B 2 3996 7106 5709 644 1145 110 C ATOM 1041 O4' DC B 2 35.065 -61.470 17.283 1.00 41.49 O ANISOU 1041 O4' DC B 2 3926 6493 5347 322 1272 146 O ATOM 1042 C3' DC B 2 36.807 -60.494 18.527 1.00 42.93 C ANISOU 1042 C3' DC B 2 3630 7223 5460 634 1188 -53 C ATOM 1043 O3' DC B 2 37.529 -61.462 19.307 1.00 46.03 O ANISOU 1043 O3' DC B 2 3844 7860 5785 1083 1409 -21 O ATOM 1044 C2' DC B 2 37.143 -60.525 17.031 1.00 43.16 C ANISOU 1044 C2' DC B 2 3887 7072 5441 189 1289 -93 C ATOM 1045 C1' DC B 2 36.241 -61.650 16.539 1.00 45.97 C ANISOU 1045 C1' DC B 2 4489 7161 5818 170 1454 43 C ATOM 1046 N1 DC B 2 35.722 -61.572 15.160 1.00 42.52 N ANISOU 1046 N1 DC B 2 4334 6502 5319 -301 1421 51 N ATOM 1047 C2 DC B 2 35.934 -62.606 14.238 1.00 41.44 C ANISOU 1047 C2 DC B 2 4336 6287 5123 -466 1729 -12 C ATOM 1048 O2 DC B 2 36.611 -63.595 14.567 1.00 44.87 O ANISOU 1048 O2 DC B 2 4654 6774 5619 -197 2046 -63 O ATOM 1049 N3 DC B 2 35.411 -62.480 12.995 1.00 42.07 N ANISOU 1049 N3 DC B 2 4656 6250 5078 -915 1667 -23 N ATOM 1050 C4 DC B 2 34.705 -61.402 12.664 1.00 41.71 C ANISOU 1050 C4 DC B 2 4730 6138 4979 -1148 1296 85 C ATOM 1051 N4 DC B 2 34.207 -61.336 11.436 1.00 42.99 N ANISOU 1051 N4 DC B 2 5127 6242 4964 -1556 1215 107 N ATOM 1052 C5 DC B 2 34.469 -60.341 13.597 1.00 40.51 C ANISOU 1052 C5 DC B 2 4442 5987 4963 -960 988 165 C ATOM 1053 C6 DC B 2 34.978 -60.478 14.822 1.00 48.94 C ANISOU 1053 C6 DC B 2 5256 7199 6141 -561 1078 114 C ATOM 1054 P DC B 3 39.108 -61.301 19.606 1.00 56.86 P ANISOU 1054 P DC B 3 4888 9643 7073 1255 1473 -226 P ATOM 1055 OP1 DC B 3 39.399 -62.194 20.765 1.00 59.09 O ANISOU 1055 OP1 DC B 3 5160 9973 7317 1696 1472 -93 O ATOM 1056 OP2 DC B 3 39.508 -59.875 19.619 1.00 48.13 O ANISOU 1056 OP2 DC B 3 3607 8699 5982 994 1254 -471 O ATOM 1057 O5' DC B 3 39.833 -61.953 18.329 1.00 60.04 O ANISOU 1057 O5' DC B 3 5427 9895 7491 1006 1746 -303 O ATOM 1058 C5' DC B 3 39.750 -63.360 18.192 1.00 53.04 C ANISOU 1058 C5' DC B 3 4652 8839 6662 1233 2036 -156 C ATOM 1059 C4' DC B 3 40.545 -63.794 16.990 1.00 48.84 C ANISOU 1059 C4' DC B 3 4175 8222 6159 942 2294 -339 C ATOM 1060 O4' DC B 3 39.812 -63.496 15.787 1.00 47.38 O ANISOU 1060 O4' DC B 3 4307 7756 5937 392 2272 -352 O ATOM 1061 C3' DC B 3 41.875 -63.081 16.866 1.00 48.27 C ANISOU 1061 C3' DC B 3 3829 8480 6033 838 2271 -637 C ATOM 1062 O3' DC B 3 42.830 -64.126 16.925 1.00 54.35 O ANISOU 1062 O3' DC B 3 4509 9207 6933 1105 2481 -692 O ATOM 1063 C2' DC B 3 41.817 -62.355 15.511 1.00 56.32 C ANISOU 1063 C2' DC B 3 5084 9336 6980 165 2271 -772 C ATOM 1064 C1' DC B 3 40.717 -63.108 14.765 1.00 51.04 C ANISOU 1064 C1' DC B 3 4768 8305 6322 -20 2373 -593 C ATOM 1065 N1 DC B 3 39.849 -62.349 13.798 1.00 45.90 N ANISOU 1065 N1 DC B 3 4433 7455 5550 -551 2192 -520 N ATOM 1066 C2 DC B 3 39.532 -62.893 12.541 1.00 47.41 C ANISOU 1066 C2 DC B 3 4882 7482 5650 -947 2369 -558 C ATOM 1067 O2 DC B 3 40.000 -63.992 12.203 1.00 51.09 O ANISOU 1067 O2 DC B 3 5300 7928 6182 -894 2717 -701 O ATOM 1068 N3 DC B 3 38.725 -62.189 11.708 1.00 46.70 N ANISOU 1068 N3 DC B 3 5069 7273 5403 -1378 2150 -450 N ATOM 1069 C4 DC B 3 38.226 -61.011 12.082 1.00 45.25 C ANISOU 1069 C4 DC B 3 4917 7053 5223 -1404 1786 -295 C ATOM 1070 N4 DC B 3 37.427 -60.362 11.227 1.00 58.67 N ANISOU 1070 N4 DC B 3 6890 8617 6785 -1784 1552 -146 N ATOM 1071 C5 DC B 3 38.531 -60.450 13.350 1.00 44.23 C ANISOU 1071 C5 DC B 3 4518 7044 5244 -1033 1644 -302 C ATOM 1072 C6 DC B 3 39.335 -61.140 14.167 1.00 44.62 C ANISOU 1072 C6 DC B 3 4292 7287 5376 -627 1846 -422 C ATOM 1073 P DA B 4 44.405 -63.814 17.014 1.00 54.50 P ANISOU 1073 P DA B 4 5992 9575 5142 1231 1477 1227 P ATOM 1074 OP1 DA B 4 44.945 -65.003 17.731 1.00 54.15 O ANISOU 1074 OP1 DA B 4 5827 10007 4742 1722 1613 1842 O ATOM 1075 OP2 DA B 4 44.647 -62.455 17.562 1.00 56.48 O ANISOU 1075 OP2 DA B 4 5989 10314 5156 692 1331 764 O ATOM 1076 O5' DA B 4 44.876 -63.755 15.483 1.00 51.00 O ANISOU 1076 O5' DA B 4 5631 8722 5025 1318 1399 1202 O ATOM 1077 C5' DA B 4 44.830 -64.920 14.684 1.00 44.09 C ANISOU 1077 C5' DA B 4 5007 7353 4392 1732 1580 1534 C ATOM 1078 C4' DA B 4 45.077 -64.566 13.235 1.00 40.84 C ANISOU 1078 C4' DA B 4 4691 6551 4276 1633 1485 1351 C ATOM 1079 O4' DA B 4 43.966 -63.783 12.736 1.00 39.67 O ANISOU 1079 O4' DA B 4 4710 5865 4498 1235 1402 929 O ATOM 1080 C3' DA B 4 46.345 -63.761 12.975 1.00 45.09 C ANISOU 1080 C3' DA B 4 4889 7660 4583 1537 1275 1300 C ATOM 1081 O3' DA B 4 47.088 -64.484 11.989 1.00 48.27 O ANISOU 1081 O3' DA B 4 5364 7907 5068 1870 1375 1581 O ATOM 1082 C2' DA B 4 45.819 -62.420 12.471 1.00 39.67 C ANISOU 1082 C2' DA B 4 4205 6706 4161 1043 1109 785 C ATOM 1083 C1' DA B 4 44.484 -62.816 11.847 1.00 38.88 C ANISOU 1083 C1' DA B 4 4475 5803 4494 1008 1216 707 C ATOM 1084 N9 DA B 4 43.488 -61.751 11.732 1.00 35.00 N ANISOU 1084 N9 DA B 4 4001 4976 4320 596 1155 343 N ATOM 1085 C8 DA B 4 43.269 -60.702 12.584 1.00 37.25 C ANISOU 1085 C8 DA B 4 4108 5470 4575 271 1150 59 C ATOM 1086 N7 DA B 4 42.284 -59.908 12.211 1.00 37.44 N ANISOU 1086 N7 DA B 4 4183 5018 5023 -14 1185 -166 N ATOM 1087 C5 DA B 4 41.828 -60.484 11.025 1.00 35.31 C ANISOU 1087 C5 DA B 4 4109 4290 5016 111 1143 -6 C ATOM 1088 C6 DA B 4 40.785 -60.137 10.133 1.00 30.82 C ANISOU 1088 C6 DA B 4 3615 3211 4883 -67 1128 -38 C ATOM 1089 N6 DA B 4 40.004 -59.064 10.279 1.00 33.29 N ANISOU 1089 N6 DA B 4 3804 3304 5542 -347 1195 -194 N ATOM 1090 N1 DA B 4 40.609 -60.933 9.059 1.00 30.20 N ANISOU 1090 N1 DA B 4 3718 2893 4865 39 1078 122 N ATOM 1091 C2 DA B 4 41.385 -61.998 8.894 1.00 29.74 C ANISOU 1091 C2 DA B 4 3800 2968 4532 322 1118 277 C ATOM 1092 N3 DA B 4 42.388 -62.438 9.660 1.00 35.49 N ANISOU 1092 N3 DA B 4 4466 4101 4918 584 1175 393 N ATOM 1093 C4 DA B 4 42.548 -61.624 10.728 1.00 34.33 C ANISOU 1093 C4 DA B 4 4097 4300 4648 453 1146 254 C ATOM 1094 P DG B 5 48.587 -64.064 11.593 1.00 52.30 P ANISOU 1094 P DG B 5 5535 8982 5356 1940 1233 1700 P ATOM 1095 OP1 DG B 5 49.253 -65.308 11.159 1.00 55.14 O ANISOU 1095 OP1 DG B 5 5970 9238 5740 2458 1508 2200 O ATOM 1096 OP2 DG B 5 49.166 -63.237 12.673 1.00 60.13 O ANISOU 1096 OP2 DG B 5 6105 10817 5926 1711 1033 1619 O ATOM 1097 O5' DG B 5 48.386 -63.218 10.261 1.00 59.28 O ANISOU 1097 O5' DG B 5 6557 9391 6576 1623 1097 1299 O ATOM 1098 C5' DG B 5 47.799 -64.009 9.249 1.00 57.47 C ANISOU 1098 C5' DG B 5 6714 8464 6660 1745 1279 1339 C ATOM 1099 C4' DG B 5 47.103 -63.130 8.258 1.00 55.70 C ANISOU 1099 C4' DG B 5 6610 7818 6735 1352 1122 956 C ATOM 1100 O4' DG B 5 46.136 -62.324 8.954 1.00 52.56 O ANISOU 1100 O4' DG B 5 6160 7375 6434 1032 1020 692 O ATOM 1101 C3' DG B 5 48.037 -62.160 7.561 1.00 54.05 C ANISOU 1101 C3' DG B 5 6167 7864 6505 1210 939 831 C ATOM 1102 O3' DG B 5 48.332 -62.792 6.342 1.00 63.88 O ANISOU 1102 O3' DG B 5 7623 8791 7856 1355 1051 941 O ATOM 1103 C2' DG B 5 47.166 -60.926 7.389 1.00 53.23 C ANISOU 1103 C2' DG B 5 6021 7547 6658 778 791 475 C ATOM 1104 C1' DG B 5 45.846 -61.323 8.030 1.00 46.81 C ANISOU 1104 C1' DG B 5 5404 6413 5970 720 882 443 C ATOM 1105 N9 DG B 5 45.201 -60.197 8.682 1.00 43.69 N ANISOU 1105 N9 DG B 5 4858 6032 5711 387 831 174 N ATOM 1106 C8 DG B 5 45.498 -59.506 9.835 1.00 43.58 C ANISOU 1106 C8 DG B 5 4610 6442 5507 225 835 7 C ATOM 1107 N7 DG B 5 44.655 -58.527 10.060 1.00 42.38 N ANISOU 1107 N7 DG B 5 4419 6044 5640 -106 892 -259 N ATOM 1108 C5 DG B 5 43.774 -58.584 8.983 1.00 34.33 C ANISOU 1108 C5 DG B 5 3567 4467 5009 -125 878 -188 C ATOM 1109 C6 DG B 5 42.662 -57.781 8.654 1.00 32.97 C ANISOU 1109 C6 DG B 5 3379 3861 5286 -374 940 -282 C ATOM 1110 O6 DG B 5 42.223 -56.818 9.301 1.00 34.67 O ANISOU 1110 O6 DG B 5 3464 4001 5706 -622 1089 -487 O ATOM 1111 N1 DG B 5 42.050 -58.193 7.449 1.00 31.07 N ANISOU 1111 N1 DG B 5 3274 3276 5256 -334 856 -94 N ATOM 1112 C2 DG B 5 42.490 -59.268 6.687 1.00 30.90 C ANISOU 1112 C2 DG B 5 3439 3279 5023 -125 778 70 C ATOM 1113 N2 DG B 5 41.812 -59.542 5.555 1.00 32.94 N ANISOU 1113 N2 DG B 5 3808 3261 5446 -213 717 179 N ATOM 1114 N3 DG B 5 43.543 -60.023 6.981 1.00 33.79 N ANISOU 1114 N3 DG B 5 3857 3943 5037 134 795 141 N ATOM 1115 C4 DG B 5 44.108 -59.607 8.137 1.00 34.28 C ANISOU 1115 C4 DG B 5 3735 4388 4903 137 822 43 C ATOM 1116 P DA B 6 49.373 -62.164 5.291 1.00 52.56 P ANISOU 1116 P DA B 6 6044 7501 6426 1310 943 898 P ATOM 1117 OP1 DA B 6 50.255 -63.259 4.869 1.00 53.08 O ANISOU 1117 OP1 DA B 6 6214 7554 6400 1692 1188 1207 O ATOM 1118 OP2 DA B 6 49.937 -60.881 5.778 1.00 46.91 O ANISOU 1118 OP2 DA B 6 4948 7255 5622 1098 730 726 O ATOM 1119 O5' DA B 6 48.445 -61.802 4.048 1.00 45.05 O ANISOU 1119 O5' DA B 6 5316 6049 5753 999 878 679 O ATOM 1120 C5' DA B 6 47.503 -62.726 3.571 1.00 44.29 C ANISOU 1120 C5' DA B 6 5575 5494 5760 971 1036 685 C ATOM 1121 C4' DA B 6 46.652 -62.023 2.539 1.00 39.73 C ANISOU 1121 C4' DA B 6 5037 4679 5379 592 872 507 C ATOM 1122 O4' DA B 6 45.774 -61.091 3.190 1.00 35.57 O ANISOU 1122 O4' DA B 6 4333 4154 5027 375 720 398 O ATOM 1123 C3' DA B 6 47.417 -61.193 1.521 1.00 37.38 C ANISOU 1123 C3' DA B 6 4580 4527 5096 493 737 475 C ATOM 1124 O3' DA B 6 46.701 -61.365 0.328 1.00 36.71 O ANISOU 1124 O3' DA B 6 4680 4193 5075 245 721 433 O ATOM 1125 C2' DA B 6 47.278 -59.742 2.015 1.00 34.18 C ANISOU 1125 C2' DA B 6 3835 4297 4854 308 549 364 C ATOM 1126 C1' DA B 6 45.924 -59.771 2.697 1.00 34.57 C ANISOU 1126 C1' DA B 6 3948 4128 5060 167 556 317 C ATOM 1127 N9 DA B 6 45.833 -58.878 3.852 1.00 30.04 N ANISOU 1127 N9 DA B 6 3135 3710 4569 89 539 197 N ATOM 1128 C8 DA B 6 46.730 -58.819 4.888 1.00 31.59 C ANISOU 1128 C8 DA B 6 3178 4291 4535 218 568 153 C ATOM 1129 N7 DA B 6 46.406 -57.941 5.820 1.00 31.86 N ANISOU 1129 N7 DA B 6 3030 4416 4658 16 591 -32 N ATOM 1130 C5 DA B 6 45.232 -57.379 5.361 1.00 32.27 C ANISOU 1130 C5 DA B 6 3112 4059 5088 -197 607 -66 C ATOM 1131 C6 DA B 6 44.411 -56.369 5.908 1.00 30.42 C ANISOU 1131 C6 DA B 6 2742 3647 5169 -450 717 -216 C ATOM 1132 N6 DA B 6 44.676 -55.762 7.078 1.00 31.76 N ANISOU 1132 N6 DA B 6 2765 4035 5267 -593 842 -457 N ATOM 1133 N1 DA B 6 43.312 -56.013 5.212 1.00 31.95 N ANISOU 1133 N1 DA B 6 2936 3458 5744 -574 732 -97 N ATOM 1134 C2 DA B 6 43.066 -56.645 4.047 1.00 31.96 C ANISOU 1134 C2 DA B 6 3068 3351 5723 -512 596 113 C ATOM 1135 N3 DA B 6 43.763 -57.619 3.448 1.00 29.57 N ANISOU 1135 N3 DA B 6 2948 3180 5108 -341 507 182 N ATOM 1136 C4 DA B 6 44.857 -57.942 4.150 1.00 27.96 C ANISOU 1136 C4 DA B 6 2742 3272 4611 -157 539 102 C ATOM 1137 P DC B 7 47.341 -60.973 -1.087 1.00 37.72 P ANISOU 1137 P DC B 7 4781 4393 5156 129 660 437 P ATOM 1138 OP1 DC B 7 46.524 -61.751 -2.051 1.00 47.03 O ANISOU 1138 OP1 DC B 7 6256 5353 6259 -124 741 387 O ATOM 1139 OP2 DC B 7 48.819 -61.078 -1.069 1.00 37.42 O ANISOU 1139 OP2 DC B 7 4675 4551 4991 419 757 501 O ATOM 1140 O5' DC B 7 47.065 -59.396 -1.231 1.00 33.60 O ANISOU 1140 O5' DC B 7 3899 4002 4864 -76 416 436 O ATOM 1141 C5' DC B 7 45.739 -58.997 -1.531 1.00 32.11 C ANISOU 1141 C5' DC B 7 3657 3686 4857 -357 307 479 C ATOM 1142 C4' DC B 7 45.667 -57.483 -1.558 1.00 35.61 C ANISOU 1142 C4' DC B 7 3728 4205 5598 -461 205 541 C ATOM 1143 O4' DC B 7 45.726 -57.026 -0.173 1.00 33.32 O ANISOU 1143 O4' DC B 7 3304 3917 5440 -372 274 421 O ATOM 1144 C3' DC B 7 46.784 -56.752 -2.285 1.00 32.58 C ANISOU 1144 C3' DC B 7 3175 3991 5211 -418 181 567 C ATOM 1145 O3' DC B 7 46.207 -55.709 -3.046 1.00 34.42 O ANISOU 1145 O3' DC B 7 3158 4211 5709 -608 112 748 O ATOM 1146 C2' DC B 7 47.590 -56.143 -1.127 1.00 29.52 C ANISOU 1146 C2' DC B 7 2600 3723 4894 -284 253 413 C ATOM 1147 C1' DC B 7 46.450 -55.828 -0.170 1.00 29.92 C ANISOU 1147 C1' DC B 7 2589 3607 5174 -396 294 373 C ATOM 1148 N1 DC B 7 46.796 -55.588 1.266 1.00 28.92 N ANISOU 1148 N1 DC B 7 2369 3597 5023 -350 390 169 N ATOM 1149 C2 DC B 7 45.970 -54.727 2.002 1.00 32.44 C ANISOU 1149 C2 DC B 7 2661 3878 5786 -526 505 83 C ATOM 1150 O2 DC B 7 44.989 -54.204 1.450 1.00 30.93 O ANISOU 1150 O2 DC B 7 2406 3439 5907 -647 524 241 O ATOM 1151 N3 DC B 7 46.248 -54.475 3.316 1.00 33.73 N ANISOU 1151 N3 DC B 7 2748 4192 5876 -570 618 -155 N ATOM 1152 C4 DC B 7 47.296 -55.069 3.870 1.00 32.01 C ANISOU 1152 C4 DC B 7 2553 4350 5260 -421 565 -232 C ATOM 1153 N4 DC B 7 47.539 -54.807 5.160 1.00 34.42 N ANISOU 1153 N4 DC B 7 2743 4915 5420 -522 654 -449 N ATOM 1154 C5 DC B 7 48.146 -55.947 3.137 1.00 30.09 C ANISOU 1154 C5 DC B 7 2426 4263 4743 -178 454 -66 C ATOM 1155 C6 DC B 7 47.871 -56.181 1.839 1.00 32.02 C ANISOU 1155 C6 DC B 7 2799 4280 5086 -159 393 97 C ATOM 1156 P DA B 8 45.963 -55.833 -4.633 1.00 31.84 P ANISOU 1156 P DA B 8 4415 3863 3818 -406 -446 -974 P ATOM 1157 OP1 DA B 8 44.817 -56.688 -4.963 1.00 32.11 O ANISOU 1157 OP1 DA B 8 4495 3827 3880 -517 -588 -1129 O ATOM 1158 OP2 DA B 8 47.284 -56.208 -5.223 1.00 34.23 O ANISOU 1158 OP2 DA B 8 4763 4262 3980 -209 -423 -1075 O ATOM 1159 O5' DA B 8 45.575 -54.318 -5.010 1.00 27.92 O ANISOU 1159 O5' DA B 8 3746 3590 3275 -413 -380 -765 O ATOM 1160 C5' DA B 8 46.505 -53.302 -4.864 1.00 24.30 C ANISOU 1160 C5' DA B 8 3219 3226 2786 -334 -264 -587 C ATOM 1161 C4' DA B 8 45.873 -52.122 -4.178 1.00 25.26 C ANISOU 1161 C4' DA B 8 3242 3324 3031 -429 -227 -385 C ATOM 1162 O4' DA B 8 45.606 -52.476 -2.799 1.00 26.76 O ANISOU 1162 O4' DA B 8 3493 3261 3415 -535 -203 -383 O ATOM 1163 C3' DA B 8 46.773 -50.889 -4.101 1.00 27.28 C ANISOU 1163 C3' DA B 8 3424 3678 3264 -360 -134 -173 C ATOM 1164 O3' DA B 8 46.453 -50.131 -5.216 1.00 29.58 O ANISOU 1164 O3' DA B 8 3637 4197 3406 -330 -172 -96 O ATOM 1165 C2' DA B 8 46.207 -50.181 -2.902 1.00 25.77 C ANISOU 1165 C2' DA B 8 3197 3332 3263 -453 -116 -45 C ATOM 1166 C1' DA B 8 45.818 -51.330 -1.995 1.00 24.06 C ANISOU 1166 C1' DA B 8 3086 2890 3167 -541 -127 -187 C ATOM 1167 N9 DA B 8 46.789 -51.726 -0.963 1.00 26.57 N ANISOU 1167 N9 DA B 8 3512 3014 3571 -518 -68 -183 N ATOM 1168 C8 DA B 8 47.847 -52.592 -1.082 1.00 30.94 C ANISOU 1168 C8 DA B 8 4166 3513 4078 -425 -69 -295 C ATOM 1169 N7 DA B 8 48.493 -52.756 0.055 1.00 27.48 N ANISOU 1169 N7 DA B 8 3818 2869 3753 -421 -38 -265 N ATOM 1170 C5 DA B 8 47.810 -51.977 0.985 1.00 22.09 C ANISOU 1170 C5 DA B 8 3101 2108 3183 -521 -3 -127 C ATOM 1171 C6 DA B 8 47.969 -51.713 2.371 1.00 27.97 C ANISOU 1171 C6 DA B 8 3917 2654 4055 -560 35 -40 C ATOM 1172 N6 DA B 8 48.940 -52.261 3.115 1.00 30.48 N ANISOU 1172 N6 DA B 8 4373 2785 4421 -507 29 -72 N ATOM 1173 N1 DA B 8 47.078 -50.859 2.959 1.00 28.54 N ANISOU 1173 N1 DA B 8 3915 2730 4197 -641 66 69 N ATOM 1174 C2 DA B 8 46.090 -50.322 2.217 1.00 27.74 C ANISOU 1174 C2 DA B 8 3673 2806 4060 -679 45 84 C ATOM 1175 N3 DA B 8 45.856 -50.501 0.909 1.00 24.92 N ANISOU 1175 N3 DA B 8 3249 2629 3592 -651 -6 18 N ATOM 1176 C4 DA B 8 46.761 -51.329 0.364 1.00 22.74 C ANISOU 1176 C4 DA B 8 3055 2354 3231 -575 -20 -82 C ATOM 1177 P DA B 9 47.563 -49.767 -6.308 1.00 32.08 P ANISOU 1177 P DA B 9 3929 4758 3500 -218 -109 -33 P ATOM 1178 OP1 DA B 9 46.821 -49.093 -7.392 1.00 31.04 O ANISOU 1178 OP1 DA B 9 3756 4821 3216 -223 -190 37 O ATOM 1179 OP2 DA B 9 48.423 -50.949 -6.589 1.00 31.36 O ANISOU 1179 OP2 DA B 9 3908 4684 3323 -124 -73 -230 O ATOM 1180 O5' DA B 9 48.507 -48.693 -5.555 1.00 34.79 O ANISOU 1180 O5' DA B 9 4216 5059 3943 -219 -9 196 O ATOM 1181 C5' DA B 9 48.061 -47.368 -5.334 1.00 31.61 C ANISOU 1181 C5' DA B 9 3750 4654 3608 -274 -42 412 C ATOM 1182 C4' DA B 9 49.286 -46.498 -5.079 1.00 27.38 C ANISOU 1182 C4' DA B 9 3168 4143 3093 -254 47 608 C ATOM 1183 O4' DA B 9 49.861 -46.797 -3.790 1.00 26.91 O ANISOU 1183 O4' DA B 9 3134 3863 3226 -251 97 581 O ATOM 1184 C3' DA B 9 50.404 -46.671 -6.080 1.00 30.10 C ANISOU 1184 C3' DA B 9 3483 4720 3232 -191 141 609 C ATOM 1185 O3' DA B 9 50.960 -45.361 -6.192 1.00 32.02 O ANISOU 1185 O3' DA B 9 3659 5038 3467 -232 170 874 O ATOM 1186 C2' DA B 9 51.384 -47.639 -5.419 1.00 26.72 C ANISOU 1186 C2' DA B 9 3076 4188 2888 -126 221 456 C ATOM 1187 C1' DA B 9 51.192 -47.367 -3.942 1.00 27.17 C ANISOU 1187 C1' DA B 9 3161 3957 3205 -175 192 514 C ATOM 1188 N9 DA B 9 51.215 -48.541 -3.076 1.00 25.40 N ANISOU 1188 N9 DA B 9 3033 3520 3097 -152 180 319 N ATOM 1189 C8 DA B 9 50.660 -49.763 -3.374 1.00 26.65 C ANISOU 1189 C8 DA B 9 3276 3651 3199 -140 130 97 C ATOM 1190 N7 DA B 9 50.783 -50.616 -2.394 1.00 26.68 N ANISOU 1190 N7 DA B 9 3384 3419 3336 -141 110 -20 N ATOM 1191 C5 DA B 9 51.438 -49.925 -1.379 1.00 25.69 C ANISOU 1191 C5 DA B 9 3241 3165 3356 -143 151 122 C ATOM 1192 C6 DA B 9 51.851 -50.297 -0.076 1.00 23.33 C ANISOU 1192 C6 DA B 9 3040 2604 3219 -140 141 96 C ATOM 1193 N6 DA B 9 51.671 -51.522 0.465 1.00 23.12 N ANISOU 1193 N6 DA B 9 3166 2380 3238 -148 88 -77 N ATOM 1194 N1 DA B 9 52.488 -49.354 0.661 1.00 23.97 N ANISOU 1194 N1 DA B 9 3075 2619 3413 -131 170 260 N ATOM 1195 C2 DA B 9 52.685 -48.148 0.134 1.00 24.03 C ANISOU 1195 C2 DA B 9 2949 2796 3385 -140 202 442 C ATOM 1196 N3 DA B 9 52.359 -47.688 -1.084 1.00 28.09 N ANISOU 1196 N3 DA B 9 3374 3556 3745 -155 216 502 N ATOM 1197 C4 DA B 9 51.720 -48.644 -1.790 1.00 27.86 C ANISOU 1197 C4 DA B 9 3392 3598 3594 -149 191 327 C ATOM 1198 P DT B 10 52.102 -45.064 -7.255 1.00 36.56 P ANISOU 1198 P DT B 10 4170 5900 3821 -216 287 975 P ATOM 1199 OP1 DT B 10 51.962 -43.629 -7.609 1.00 36.09 O ANISOU 1199 OP1 DT B 10 4088 5902 3724 -304 237 1267 O ATOM 1200 OP2 DT B 10 52.014 -46.070 -8.344 1.00 34.05 O ANISOU 1200 OP2 DT B 10 3885 5791 3262 -139 314 770 O ATOM 1201 O5' DT B 10 53.445 -45.338 -6.454 1.00 34.33 O ANISOU 1201 O5' DT B 10 3822 5545 3677 -179 403 949 O ATOM 1202 C5' DT B 10 53.743 -44.495 -5.367 1.00 30.91 C ANISOU 1202 C5' DT B 10 3361 4909 3476 -233 379 1117 C ATOM 1203 C4' DT B 10 55.006 -44.969 -4.722 1.00 26.79 C ANISOU 1203 C4' DT B 10 2780 4331 3066 -175 471 1039 C ATOM 1204 O4' DT B 10 54.684 -46.053 -3.822 1.00 28.51 O ANISOU 1204 O4' DT B 10 3096 4319 3417 -110 424 813 O ATOM 1205 C3' DT B 10 56.059 -45.494 -5.694 1.00 28.85 C ANISOU 1205 C3' DT B 10 2945 4883 3133 -111 609 950 C ATOM 1206 O3' DT B 10 56.922 -44.398 -5.929 1.00 37.69 O ANISOU 1206 O3' DT B 10 3940 6136 4244 -194 684 1198 O ATOM 1207 C2' DT B 10 56.730 -46.584 -4.868 1.00 25.96 C ANISOU 1207 C2' DT B 10 2591 4364 2910 3 623 715 C ATOM 1208 C1' DT B 10 55.947 -46.664 -3.560 1.00 28.19 C ANISOU 1208 C1' DT B 10 3000 4288 3422 -23 500 699 C ATOM 1209 N1 DT B 10 55.578 -48.033 -3.113 1.00 27.14 N ANISOU 1209 N1 DT B 10 2996 3987 3329 55 444 431 N ATOM 1210 C2 DT B 10 55.816 -48.420 -1.808 1.00 27.16 C ANISOU 1210 C2 DT B 10 3080 3699 3541 80 391 368 C ATOM 1211 O2 DT B 10 56.344 -47.695 -0.986 1.00 29.17 O ANISOU 1211 O2 DT B 10 3298 3832 3953 58 387 507 O ATOM 1212 N3 DT B 10 55.429 -49.699 -1.467 1.00 26.38 N ANISOU 1212 N3 DT B 10 3124 3438 3460 129 326 139 N ATOM 1213 C4 DT B 10 54.820 -50.601 -2.301 1.00 28.95 C ANISOU 1213 C4 DT B 10 3509 3857 3634 156 299 -38 C ATOM 1214 O4 DT B 10 54.486 -51.719 -1.890 1.00 26.12 O ANISOU 1214 O4 DT B 10 3293 3311 3319 180 219 -226 O ATOM 1215 C5 DT B 10 54.577 -50.135 -3.649 1.00 27.54 C ANISOU 1215 C5 DT B 10 3233 3989 3243 144 352 21 C ATOM 1216 C7 DT B 10 53.911 -51.058 -4.640 1.00 31.09 C ANISOU 1216 C7 DT B 10 3747 4554 3511 184 305 -177 C ATOM 1217 C6 DT B 10 54.965 -48.885 -4.015 1.00 26.97 C ANISOU 1217 C6 DT B 10 3030 4089 3130 94 426 256 C ATOM 1218 P DG B 11 57.902 -44.355 -7.182 1.00 41.43 P ANISOU 1218 P DG B 11 4276 7002 4462 -198 854 1234 P ATOM 1219 OP1 DG B 11 58.259 -42.922 -7.332 1.00 41.81 O ANISOU 1219 OP1 DG B 11 4293 7030 4561 -336 819 1507 O ATOM 1220 OP2 DG B 11 57.368 -45.151 -8.296 1.00 37.67 O ANISOU 1220 OP2 DG B 11 3862 6743 3708 -123 877 1058 O ATOM 1221 O5' DG B 11 59.236 -45.113 -6.660 1.00 30.67 O ANISOU 1221 O5' DG B 11 2785 5649 3218 -87 955 1049 O ATOM 1222 C5' DG B 11 60.027 -44.511 -5.671 1.00 38.01 C ANISOU 1222 C5' DG B 11 3627 6412 4403 -133 946 1173 C ATOM 1223 C4' DG B 11 60.965 -45.594 -5.219 1.00 28.01 C ANISOU 1223 C4' DG B 11 2289 5122 3230 25 990 900 C ATOM 1224 O4' DG B 11 60.189 -46.635 -4.599 1.00 27.34 O ANISOU 1224 O4' DG B 11 2390 4780 3217 131 867 667 O ATOM 1225 C3' DG B 11 61.677 -46.239 -6.406 1.00 30.96 C ANISOU 1225 C3' DG B 11 2529 5884 3349 115 1154 738 C ATOM 1226 O3' DG B 11 62.995 -46.438 -6.010 1.00 34.58 O ANISOU 1226 O3' DG B 11 2805 6392 3943 186 1228 650 O ATOM 1227 C2' DG B 11 60.986 -47.587 -6.534 1.00 30.59 C ANISOU 1227 C2' DG B 11 2643 5763 3219 272 1077 422 C ATOM 1228 C1' DG B 11 60.692 -47.869 -5.077 1.00 27.86 C ANISOU 1228 C1' DG B 11 2428 4987 3170 296 920 368 C ATOM 1229 N9 DG B 11 59.712 -48.928 -4.846 1.00 28.24 N ANISOU 1229 N9 DG B 11 2683 4835 3213 370 795 152 N ATOM 1230 C8 DG B 11 58.725 -49.405 -5.691 1.00 27.36 C ANISOU 1230 C8 DG B 11 2677 4820 2900 377 765 59 C ATOM 1231 N7 DG B 11 58.024 -50.380 -5.183 1.00 28.37 N ANISOU 1231 N7 DG B 11 2977 4701 3101 427 638 -132 N ATOM 1232 C5 DG B 11 58.579 -50.552 -3.900 1.00 25.76 C ANISOU 1232 C5 DG B 11 2676 4091 3022 458 583 -158 C ATOM 1233 C6 DG B 11 58.291 -51.479 -2.871 1.00 27.87 C ANISOU 1233 C6 DG B 11 3121 4017 3451 503 450 -318 C ATOM 1234 O6 DG B 11 57.400 -52.343 -2.843 1.00 32.34 O ANISOU 1234 O6 DG B 11 3854 4444 3991 502 352 -462 O ATOM 1235 N1 DG B 11 59.117 -51.304 -1.750 1.00 24.19 N ANISOU 1235 N1 DG B 11 2641 3351 3200 532 423 -282 N ATOM 1236 C2 DG B 11 60.123 -50.374 -1.637 1.00 24.68 C ANISOU 1236 C2 DG B 11 2517 3525 3336 521 506 -127 C ATOM 1237 N2 DG B 11 60.837 -50.348 -0.484 1.00 24.73 N ANISOU 1237 N2 DG B 11 2538 3295 3563 563 440 -128 N ATOM 1238 N3 DG B 11 60.444 -49.535 -2.610 1.00 28.05 N ANISOU 1238 N3 DG B 11 2759 4275 3625 465 639 23 N ATOM 1239 C4 DG B 11 59.606 -49.667 -3.691 1.00 25.21 C ANISOU 1239 C4 DG B 11 2435 4110 3035 434 671 6 C ATOM 1240 P DC B 12 64.186 -46.345 -7.058 1.00 40.49 P ANISOU 1240 P DC B 12 3464 6572 5348 518 931 867 P ATOM 1241 OP1 DC B 12 64.297 -44.946 -7.499 1.00 41.39 O ANISOU 1241 OP1 DC B 12 3508 6680 5536 427 929 1033 O ATOM 1242 OP2 DC B 12 63.976 -47.477 -8.013 1.00 41.42 O ANISOU 1242 OP2 DC B 12 3658 6730 5348 565 1001 659 O ATOM 1243 O5' DC B 12 65.502 -46.681 -6.172 1.00 38.99 O ANISOU 1243 O5' DC B 12 3003 6377 5433 603 801 956 O ATOM 1244 C5' DC B 12 65.553 -46.141 -4.879 1.00 45.65 C ANISOU 1244 C5' DC B 12 3788 7106 6452 628 635 1112 C ATOM 1245 C4' DC B 12 65.726 -47.235 -3.827 1.00 35.18 C ANISOU 1245 C4' DC B 12 2662 5603 5100 783 448 961 C ATOM 1246 O4' DC B 12 64.518 -48.032 -3.728 1.00 39.59 O ANISOU 1246 O4' DC B 12 3565 6168 5310 818 632 816 O ATOM 1247 C3' DC B 12 66.872 -48.212 -4.015 1.00 42.11 C ANISOU 1247 C3' DC B 12 3315 6534 6149 924 353 865 C ATOM 1248 O3' DC B 12 67.653 -48.087 -2.882 1.00 43.60 O ANISOU 1248 O3' DC B 12 3644 6385 6536 957 -46 815 O ATOM 1249 C2' DC B 12 66.250 -49.587 -3.980 1.00 41.95 C ANISOU 1249 C2' DC B 12 3574 6520 5845 1043 463 659 C ATOM 1250 C1' DC B 12 64.902 -49.340 -3.340 1.00 41.82 C ANISOU 1250 C1' DC B 12 3996 6337 5558 954 533 642 C ATOM 1251 N1 DC B 12 63.865 -50.230 -3.881 1.00 35.71 N ANISOU 1251 N1 DC B 12 3330 5703 4536 979 814 520 N ATOM 1252 C2 DC B 12 63.332 -51.211 -3.045 1.00 31.98 C ANISOU 1252 C2 DC B 12 3276 4974 3901 1024 777 379 C ATOM 1253 O2 DC B 12 63.763 -51.290 -1.874 1.00 32.57 O ANISOU 1253 O2 DC B 12 3653 4729 3994 1073 515 368 O ATOM 1254 N3 DC B 12 62.387 -52.035 -3.550 1.00 30.94 N ANISOU 1254 N3 DC B 12 3205 4937 3615 1026 1017 261 N ATOM 1255 C4 DC B 12 61.992 -51.923 -4.820 1.00 33.36 C ANISOU 1255 C4 DC B 12 3302 5434 3939 906 1117 208 C ATOM 1256 N4 DC B 12 61.046 -52.773 -5.237 1.00 30.97 N ANISOU 1256 N4 DC B 12 3138 5042 3588 810 1176 34 N ATOM 1257 C5 DC B 12 62.534 -50.927 -5.694 1.00 30.75 C ANISOU 1257 C5 DC B 12 2747 5211 3727 807 1053 300 C ATOM 1258 C6 DC B 12 63.459 -50.107 -5.181 1.00 40.49 C ANISOU 1258 C6 DC B 12 3791 6502 5092 870 978 485 C ATOM 1259 P DT B 13 69.079 -48.814 -2.790 1.00 53.43 P ANISOU 1259 P DT B 13 4641 7597 8062 1105 -281 712 P ATOM 1260 OP1 DT B 13 69.828 -47.982 -1.813 1.00 54.20 O ANISOU 1260 OP1 DT B 13 4757 7371 8467 1075 -702 733 O ATOM 1261 OP2 DT B 13 69.636 -49.178 -4.127 1.00 46.62 O ANISOU 1261 OP2 DT B 13 3320 7110 7284 1133 -10 737 O ATOM 1262 O5' DT B 13 68.745 -50.222 -2.135 1.00 43.65 O ANISOU 1262 O5' DT B 13 3859 6187 6539 1276 -358 479 O ATOM 1263 C5' DT B 13 68.373 -50.282 -0.783 1.00 43.41 C ANISOU 1263 C5' DT B 13 4373 5769 6350 1323 -615 397 C ATOM 1264 C4' DT B 13 68.231 -51.745 -0.459 1.00 37.70 C ANISOU 1264 C4' DT B 13 3977 4939 5409 1489 -618 218 C ATOM 1265 O4' DT B 13 67.100 -52.319 -1.166 1.00 33.32 O ANISOU 1265 O4' DT B 13 3488 4576 4596 1428 -227 209 O ATOM 1266 C3' DT B 13 69.444 -52.558 -0.854 1.00 39.46 C ANISOU 1266 C3' DT B 13 3894 5254 5845 1652 -759 98 C ATOM 1267 O3' DT B 13 69.879 -53.166 0.332 1.00 38.08 O ANISOU 1267 O3' DT B 13 4129 4712 5626 1831 -1120 -46 O ATOM 1268 C2' DT B 13 68.950 -53.587 -1.864 1.00 38.08 C ANISOU 1268 C2' DT B 13 3625 5346 5497 1692 -429 26 C ATOM 1269 C1' DT B 13 67.476 -53.639 -1.533 1.00 36.59 C ANISOU 1269 C1' DT B 13 3867 5044 4990 1580 -214 53 C ATOM 1270 N1 DT B 13 66.565 -53.893 -2.664 1.00 37.84 N ANISOU 1270 N1 DT B 13 3860 5506 5013 1508 167 54 N ATOM 1271 C2 DT B 13 65.605 -54.871 -2.546 1.00 36.11 C ANISOU 1271 C2 DT B 13 3965 5177 4578 1517 312 -55 C ATOM 1272 O2 DT B 13 65.491 -55.568 -1.554 1.00 39.66 O ANISOU 1272 O2 DT B 13 4847 5291 4931 1578 175 -121 O ATOM 1273 N3 DT B 13 64.787 -54.994 -3.634 1.00 33.57 N ANISOU 1273 N3 DT B 13 3445 5137 4172 1462 617 -82 N ATOM 1274 C4 DT B 13 64.868 -54.251 -4.796 1.00 33.34 C ANISOU 1274 C4 DT B 13 2974 5493 4200 1435 794 1 C ATOM 1275 O4 DT B 13 64.090 -54.440 -5.717 1.00 35.06 O ANISOU 1275 O4 DT B 13 3188 5797 4336 1301 949 -59 O ATOM 1276 C5 DT B 13 65.902 -53.248 -4.857 1.00 38.96 C ANISOU 1276 C5 DT B 13 3380 6302 5120 1419 675 158 C ATOM 1277 C7 DT B 13 66.059 -52.391 -6.083 1.00 40.21 C ANISOU 1277 C7 DT B 13 3320 6613 5344 1206 787 248 C ATOM 1278 C6 DT B 13 66.701 -53.110 -3.795 1.00 36.23 C ANISOU 1278 C6 DT B 13 3182 5669 4915 1441 361 170 C ATOM 1279 P DA B 14 71.255 -53.978 0.372 1.00 50.35 P ANISOU 1279 P DA B 14 5489 6231 7410 2057 -1424 -220 P ATOM 1280 OP1 DA B 14 71.652 -54.052 1.795 1.00 52.17 O ANISOU 1280 OP1 DA B 14 6180 6030 7613 2225 -1872 -328 O ATOM 1281 OP2 DA B 14 72.185 -53.433 -0.645 1.00 53.85 O ANISOU 1281 OP2 DA B 14 5230 7004 8227 2004 -1366 -150 O ATOM 1282 O5' DA B 14 70.841 -55.440 -0.105 1.00 42.99 O ANISOU 1282 O5' DA B 14 4712 5384 6239 2169 -1217 -346 O ATOM 1283 C5' DA B 14 70.019 -56.207 0.729 1.00 46.82 C ANISOU 1283 C5' DA B 14 5821 5561 6406 2224 -1216 -400 C ATOM 1284 C4' DA B 14 69.685 -57.468 -0.013 1.00 51.66 C ANISOU 1284 C4' DA B 14 6426 6302 6900 2288 -1003 -511 C ATOM 1285 O4' DA B 14 68.817 -57.097 -1.111 1.00 50.47 O ANISOU 1285 O4' DA B 14 5989 6488 6700 2103 -600 -417 O ATOM 1286 C3' DA B 14 70.864 -58.196 -0.666 1.00 56.47 C ANISOU 1286 C3' DA B 14 6661 7089 7708 2494 -1153 -673 C ATOM 1287 O3' DA B 14 70.592 -59.571 -0.634 1.00 69.30 O ANISOU 1287 O3' DA B 14 8592 8572 9167 2634 -1151 -824 O ATOM 1288 C2' DA B 14 70.773 -57.790 -2.126 1.00 52.87 C ANISOU 1288 C2' DA B 14 5627 7117 7345 2397 -820 -604 C ATOM 1289 C1' DA B 14 69.252 -57.908 -2.180 1.00 52.91 C ANISOU 1289 C1' DA B 14 5957 7070 7076 2232 -517 -546 C ATOM 1290 N9 DA B 14 68.601 -57.471 -3.397 1.00 49.75 N ANISOU 1290 N9 DA B 14 5208 7052 6640 2111 -159 -470 N ATOM 1291 C8 DA B 14 68.950 -56.453 -4.246 1.00 44.16 C ANISOU 1291 C8 DA B 14 4011 6696 6074 2042 -13 -331 C ATOM 1292 N7 DA B 14 68.127 -56.318 -5.261 1.00 42.97 N ANISOU 1292 N7 DA B 14 3717 6812 5796 1956 306 -294 N ATOM 1293 C5 DA B 14 67.179 -57.315 -5.042 1.00 38.99 C ANISOU 1293 C5 DA B 14 3574 6142 5100 1991 358 -444 C ATOM 1294 C6 DA B 14 66.045 -57.693 -5.779 1.00 38.47 C ANISOU 1294 C6 DA B 14 3571 6162 4884 1894 596 -505 C ATOM 1295 N6 DA B 14 65.711 -57.071 -6.913 1.00 45.03 N ANISOU 1295 N6 DA B 14 4253 7147 5710 1653 748 -400 N ATOM 1296 N1 DA B 14 65.304 -58.718 -5.309 1.00 47.14 N ANISOU 1296 N1 DA B 14 5012 7017 5883 1947 593 -656 N ATOM 1297 C2 DA B 14 65.689 -59.335 -4.179 1.00 52.37 C ANISOU 1297 C2 DA B 14 6047 7294 6559 1994 360 -689 C ATOM 1298 N3 DA B 14 66.739 -59.065 -3.399 1.00 52.85 N ANISOU 1298 N3 DA B 14 6162 7207 6710 2070 93 -639 N ATOM 1299 C4 DA B 14 67.444 -58.031 -3.902 1.00 45.70 C ANISOU 1299 C4 DA B 14 4829 6594 5941 2056 98 -528 C ATOM 1300 P DG B 15 71.668 -60.616 -0.057 1.00 63.81 P ANISOU 1300 P DG B 15 8079 7638 8528 2939 -1551 -1032 P ATOM 1301 OP1 DG B 15 71.663 -60.483 1.413 1.00 67.04 O ANISOU 1301 OP1 DG B 15 9052 7597 8822 2999 -1830 -1002 O ATOM 1302 OP2 DG B 15 72.935 -60.458 -0.817 1.00 64.69 O ANISOU 1302 OP2 DG B 15 7588 8073 8917 3031 -1655 -1111 O ATOM 1303 O5' DG B 15 71.013 -62.029 -0.417 1.00 54.44 O ANISOU 1303 O5' DG B 15 7152 6371 7161 3012 -1410 -1156 O ATOM 1304 C5' DG B 15 69.632 -62.228 -0.146 1.00 48.86 C ANISOU 1304 C5' DG B 15 6847 5477 6241 2827 -1144 -1054 C ATOM 1305 C4' DG B 15 69.010 -63.142 -1.186 1.00 51.08 C ANISOU 1305 C4' DG B 15 6999 5914 6494 2818 -914 -1167 C ATOM 1306 O4' DG B 15 68.450 -62.303 -2.232 1.00 49.60 O ANISOU 1306 O4' DG B 15 6374 6136 6337 2639 -597 -1084 O ATOM 1307 C3' DG B 15 69.971 -64.107 -1.883 1.00 59.31 C ANISOU 1307 C3' DG B 15 7792 7100 7642 3096 -1106 -1402 C ATOM 1308 O3' DG B 15 69.359 -65.344 -2.233 1.00 72.61 O ANISOU 1308 O3' DG B 15 9678 8650 9262 3149 -1046 -1545 O ATOM 1309 C2' DG B 15 70.274 -63.369 -3.178 1.00 54.44 C ANISOU 1309 C2' DG B 15 6514 7031 7140 3079 -917 -1390 C ATOM 1310 C1' DG B 15 68.890 -62.827 -3.469 1.00 48.97 C ANISOU 1310 C1' DG B 15 5872 6401 6334 2802 -563 -1249 C ATOM 1311 N9 DG B 15 68.931 -61.784 -4.482 1.00 44.48 N ANISOU 1311 N9 DG B 15 4782 6297 5823 2724 -337 -1148 N ATOM 1312 C8 DG B 15 69.843 -60.762 -4.590 1.00 45.45 C ANISOU 1312 C8 DG B 15 4544 6631 6094 2694 -380 -1015 C ATOM 1313 N7 DG B 15 69.625 -59.978 -5.612 1.00 41.71 N ANISOU 1313 N7 DG B 15 3749 6479 5620 2482 -101 -859 N ATOM 1314 C5 DG B 15 68.511 -60.520 -6.220 1.00 41.89 C ANISOU 1314 C5 DG B 15 3905 6534 5478 2412 93 -925 C ATOM 1315 C6 DG B 15 67.836 -60.100 -7.385 1.00 44.28 C ANISOU 1315 C6 DG B 15 4074 7045 5705 2197 348 -825 C ATOM 1316 O6 DG B 15 68.099 -59.126 -8.101 1.00 43.58 O ANISOU 1316 O6 DG B 15 3771 7123 5665 2036 475 -648 O ATOM 1317 N1 DG B 15 66.744 -60.917 -7.664 1.00 49.82 N ANISOU 1317 N1 DG B 15 4973 7661 6295 2180 416 -958 N ATOM 1318 C2 DG B 15 66.373 -62.014 -6.919 1.00 51.91 C ANISOU 1318 C2 DG B 15 5527 7656 6541 2333 300 -1153 C ATOM 1319 N2 DG B 15 65.293 -62.687 -7.347 1.00 50.89 N ANISOU 1319 N2 DG B 15 5520 7447 6368 2261 393 -1259 N ATOM 1320 N3 DG B 15 67.007 -62.420 -5.823 1.00 48.95 N ANISOU 1320 N3 DG B 15 5362 7023 6212 2534 77 -1232 N ATOM 1321 C4 DG B 15 68.060 -61.623 -5.533 1.00 45.48 C ANISOU 1321 C4 DG B 15 4728 6687 5867 2574 -37 -1117 C ATOM 1322 P DT B 16 69.784 -66.710 -1.500 1.00 85.73 P ATOM 1323 OP1 DT B 16 68.960 -66.791 -0.269 1.00 82.65 O ATOM 1324 OP2 DT B 16 71.261 -66.765 -1.424 1.00 87.55 O ATOM 1325 O5' DT B 16 69.331 -67.854 -2.525 1.00 87.87 O TER 1326 DT B 16 HETATM 1327 O HOH C 101 60.873 -33.351 4.298 1.00 38.62 O HETATM 1328 O HOH C 102 42.379 -58.411 -16.009 1.00 41.23 O HETATM 1329 O HOH C 103 37.227 -39.553 -8.701 1.00 57.63 O HETATM 1330 O HOH C 104 45.352 -32.087 13.877 1.00 41.98 O HETATM 1331 O HOH C 105 50.906 -38.083 14.538 1.00 40.55 O HETATM 1332 O HOH C 106 70.241 -47.351 0.838 1.00 52.70 O HETATM 1333 O HOH C 107 65.975 -34.791 -4.048 1.00 38.75 O HETATM 1334 O HOH C 108 39.468 -36.827 11.489 1.00 61.93 O HETATM 1335 O HOH C 109 50.447 -33.749 9.010 1.00 33.00 O HETATM 1336 O HOH C 110 65.481 -32.648 -5.527 1.00 38.86 O HETATM 1337 O HOH C 111 64.468 -36.217 7.649 1.00 32.98 O HETATM 1338 O HOH C 112 28.569 -51.364 -14.221 1.00 57.69 O HETATM 1339 O HOH C 113 54.017 -32.357 15.680 1.00 65.24 O HETATM 1340 O HOH C 114 55.804 -37.351 9.955 1.00 26.87 O HETATM 1341 O HOH C 115 36.536 -31.882 0.282 1.00 41.18 O HETATM 1342 O HOH C 116 55.073 -33.041 -5.015 1.00 43.46 O HETATM 1343 O HOH C 117 48.704 -35.767 -0.888 1.00 29.54 O HETATM 1344 O HOH C 118 60.998 -46.661 13.828 1.00 31.07 O HETATM 1345 O HOH C 119 31.350 -62.030 -9.086 1.00 45.43 O HETATM 1346 O HOH C 120 37.791 -29.508 4.338 1.00 37.05 O HETATM 1347 O HOH C 121 52.250 -30.934 -3.148 1.00 36.89 O HETATM 1348 O HOH C 122 47.625 -58.820 -14.483 1.00 45.35 O HETATM 1349 O HOH C 123 41.705 -59.282 -9.095 1.00 45.78 O HETATM 1350 O HOH C 124 64.537 -39.334 -3.607 1.00 54.01 O HETATM 1351 O HOH C 125 60.329 -37.509 -5.264 1.00 48.95 O HETATM 1352 O HOH C 126 73.427 -37.252 2.237 1.00 36.07 O HETATM 1353 O HOH C 127 37.245 -60.547 -8.430 1.00 43.38 O HETATM 1354 O HOH C 128 38.208 -34.759 -3.086 1.00 29.56 O HETATM 1355 O HOH C 129 43.131 -31.046 2.356 1.00 38.18 O HETATM 1356 O HOH C 130 31.591 -62.117 -13.774 1.00 43.74 O HETATM 1357 O HOH C 131 66.732 -37.158 5.435 1.00 31.28 O HETATM 1358 O HOH C 132 45.015 -35.051 14.797 1.00 53.27 O HETATM 1359 O HOH C 133 66.639 -45.051 5.281 1.00 27.85 O HETATM 1360 O HOH C 134 28.603 -50.580 -1.460 1.00 40.06 O HETATM 1361 O HOH C 135 42.206 -46.780 -6.599 1.00 28.99 O HETATM 1362 O HOH C 136 53.428 -36.511 14.587 1.00 56.06 O HETATM 1363 O HOH C 137 62.494 -48.758 9.401 1.00 38.60 O HETATM 1364 O HOH C 138 42.864 -26.627 8.711 1.00 54.26 O HETATM 1365 O HOH C 139 63.423 -49.814 12.566 1.00 42.32 O HETATM 1366 O HOH C 140 53.887 -29.102 0.805 1.00 44.87 O HETATM 1367 O HOH C 141 47.772 -45.330 -8.138 1.00 45.77 O HETATM 1368 O HOH C 142 67.758 -37.474 3.208 1.00 29.50 O HETATM 1369 O HOH C 143 51.292 -42.684 15.053 1.00 41.05 O HETATM 1370 O HOH C 144 60.244 -40.202 -5.415 1.00 53.02 O HETATM 1371 O HOH C 145 40.268 -60.502 -7.187 1.00 49.46 O HETATM 1372 O HOH C 146 66.821 -32.539 -0.872 1.00 53.01 O HETATM 1373 O HOH C 147 67.976 -51.495 3.738 1.00 61.93 O HETATM 1374 O HOH C 148 39.821 -27.535 11.315 1.00 44.66 O HETATM 1375 O HOH C 149 36.243 -29.863 10.059 1.00 37.27 O HETATM 1376 O HOH C 150 49.994 -31.043 0.855 1.00 45.75 O HETATM 1377 O HOH C 151 31.220 -34.817 -1.443 1.00 71.66 O HETATM 1378 O HOH C 152 37.423 -32.175 -2.326 1.00 45.06 O HETATM 1379 O HOH C 153 58.269 -38.400 -11.847 1.00 50.62 O HETATM 1380 O HOH C 154 27.472 -42.186 -5.209 1.00 41.62 O HETATM 1381 O HOH C 155 57.259 -44.925 14.515 1.00 42.06 O HETATM 1382 O HOH C 156 29.330 -42.341 -14.176 1.00 66.28 O HETATM 1383 O HOH C 157 34.164 -33.554 7.615 1.00 52.51 O HETATM 1384 O HOH C 158 27.051 -43.730 -2.634 1.00 46.78 O HETATM 1385 O HOH C 159 38.272 -44.653 -10.685 1.00 38.60 O HETATM 1386 O HOH C 160 46.841 -42.120 17.206 1.00 55.46 O HETATM 1387 O HOH C 161 30.579 -40.978 -5.999 1.00 51.43 O HETATM 1388 O HOH C 162 45.340 -29.325 2.839 1.00 52.12 O HETATM 1389 O HOH C 163 59.564 -43.471 -2.547 1.00 30.90 O HETATM 1390 O HOH C 164 37.748 -35.997 7.047 1.00 28.55 O HETATM 1391 O HOH C 165 38.547 -46.495 -2.240 1.00 25.48 O HETATM 1392 O HOH C 166 36.623 -42.788 2.377 1.00 30.78 O HETATM 1393 O HOH C 167 49.816 -44.583 -1.738 1.00 29.27 O HETATM 1394 O HOH C 168 37.482 -48.406 -10.903 1.00 34.62 O HETATM 1395 O HOH C 169 39.052 -44.672 2.989 1.00 31.13 O HETATM 1396 O HOH C 170 37.818 -46.754 -8.833 1.00 32.28 O HETATM 1397 O HOH C 171 43.701 -49.124 -7.093 1.00 34.09 O HETATM 1398 O HOH C 172 63.703 -41.148 -0.112 1.00 30.56 O HETATM 1399 O HOH C 173 42.326 -57.057 -5.829 1.00 36.04 O HETATM 1400 O HOH C 174 34.544 -50.760 -4.315 1.00 34.94 O HETATM 1401 O HOH C 175 54.045 -44.396 11.775 1.00 31.89 O HETATM 1402 O HOH C 176 52.483 -44.832 -1.275 1.00 34.70 O HETATM 1403 O HOH C 177 38.277 -37.836 8.836 1.00 37.36 O HETATM 1404 O HOH C 178 46.915 -54.519 -12.250 1.00 40.47 O HETATM 1405 O HOH C 179 62.278 -43.141 -2.276 1.00 36.59 O HETATM 1406 O HOH C 180 32.684 -38.877 -1.897 1.00 34.94 O HETATM 1407 O HOH C 181 41.344 -60.134 -5.007 1.00 40.68 O HETATM 1408 O HOH C 182 40.070 -50.127 -0.341 1.00 37.67 O HETATM 1409 O HOH C 183 39.801 -49.405 -11.839 1.00 45.01 O HETATM 1410 O HOH C 184 63.005 -48.069 -0.228 1.00 34.86 O HETATM 1411 O HOH C 185 34.286 -53.375 -7.353 1.00 42.51 O HETATM 1412 O HOH C 186 40.092 -47.803 -8.069 1.00 36.44 O HETATM 1413 O HOH C 187 49.139 -33.056 3.865 1.00 43.01 O HETATM 1414 O HOH C 188 42.837 -52.304 -10.997 1.00 38.91 O HETATM 1415 O HOH C 189 35.136 -44.917 1.504 1.00 37.31 O HETATM 1416 O HOH C 190 31.674 -38.768 0.518 1.00 43.01 O HETATM 1417 O HOH C 191 35.067 -35.849 6.558 1.00 42.26 O HETATM 1418 O HOH C 192 29.107 -42.393 -1.599 1.00 39.83 O HETATM 1419 O HOH C 193 51.293 -45.410 1.415 1.00 36.70 O HETATM 1420 O HOH C 194 59.859 -51.194 12.486 1.00 43.91 O HETATM 1421 O HOH C 195 33.070 -51.317 -1.799 1.00 43.48 O HETATM 1422 O HOH C 196 48.387 -33.312 0.639 1.00 38.57 O HETATM 1423 O HOH C 197 32.061 -42.311 -7.540 1.00 39.50 O HETATM 1424 O HOH C 198 38.829 -54.595 -2.052 1.00 48.45 O HETATM 1425 O HOH C 199 35.631 -31.278 7.924 1.00 38.99 O HETATM 1426 O HOH C 200 51.148 -33.343 6.412 1.00 44.14 O HETATM 1427 O HOH C 201 33.028 -35.693 4.008 1.00 56.77 O HETATM 1428 O HOH C 202 35.648 -29.400 5.927 1.00 44.91 O HETATM 1429 O HOH C 203 66.022 -51.333 2.299 1.00 47.15 O HETATM 1430 O HOH C 204 38.229 -48.379 -0.326 1.00 42.74 O HETATM 1431 O HOH C 205 37.475 -46.271 0.948 1.00 44.66 O HETATM 1432 O HOH C 206 30.793 -40.629 -3.299 1.00 45.22 O HETATM 1433 O HOH C 207 74.038 -38.988 0.143 1.00 54.25 O HETATM 1434 O HOH C 208 54.831 -41.503 -4.383 1.00 40.11 O HETATM 1435 O HOH C 209 41.226 -50.427 -9.533 1.00 60.93 O HETATM 1436 O HOH C 210 33.054 -39.092 2.308 1.00 51.21 O HETATM 1437 O HOH C 211 44.049 -39.946 12.535 1.00 51.48 O HETATM 1438 O HOH C 212 32.875 -55.251 -6.201 1.00 56.73 O HETATM 1439 O HOH C 213 33.534 -41.846 3.552 1.00 46.88 O HETATM 1440 O HOH C 214 46.486 -52.022 -13.691 1.00 67.52 O HETATM 1441 O HOH C 215 46.018 -31.377 3.487 1.00 69.61 O HETATM 1442 O HOH A 101 34.000 -61.864 6.853 1.00 61.86 O HETATM 1443 O HOH A 102 42.689 -54.046 10.661 1.00 37.48 O HETATM 1444 O HOH A 103 35.317 -64.506 18.113 1.00 56.00 O HETATM 1445 O HOH A 104 69.848 -56.880 -13.171 1.00 44.54 O HETATM 1446 O HOH A 105 32.421 -60.291 4.947 1.00 54.99 O HETATM 1447 O HOH A 106 43.634 -52.041 12.104 1.00 48.35 O HETATM 1448 O HOH A 107 41.466 -50.336 1.820 1.00 27.44 O HETATM 1449 O HOH A 108 62.004 -49.871 2.601 1.00 29.53 O HETATM 1450 O HOH A 109 51.155 -54.080 3.100 1.00 32.42 O HETATM 1451 O HOH A 110 47.042 -48.955 11.643 1.00 32.37 O HETATM 1452 O HOH A 111 51.530 -43.854 12.778 1.00 33.72 O HETATM 1453 O HOH A 112 49.151 -53.878 7.706 1.00 36.66 O HETATM 1454 O HOH A 113 45.738 -50.853 10.402 1.00 38.48 O HETATM 1455 O HOH A 114 54.689 -55.537 4.203 1.00 42.51 O HETATM 1456 O HOH A 115 38.121 -53.841 10.258 1.00 41.11 O HETATM 1457 O HOH A 116 42.547 -48.011 10.542 1.00 41.02 O HETATM 1458 O HOH A 117 53.866 -55.278 1.359 1.00 37.52 O HETATM 1459 O HOH A 118 50.952 -49.778 12.196 1.00 40.23 O HETATM 1460 O HOH A 119 34.890 -57.975 -2.092 1.00 40.13 O HETATM 1461 O HOH A 120 35.965 -57.727 9.723 1.00 48.61 O HETATM 1462 O HOH A 121 51.045 -53.742 9.687 1.00 37.44 O HETATM 1463 O HOH A 122 55.187 -46.234 13.088 1.00 44.08 O HETATM 1464 O HOH A 123 55.006 -56.347 -0.838 1.00 47.78 O HETATM 1465 O HOH A 124 37.592 -50.266 7.905 1.00 48.90 O HETATM 1466 O HOH A 125 35.030 -46.850 3.767 1.00 45.79 O HETATM 1467 O HOH A 126 63.677 -54.246 2.586 1.00 64.65 O HETATM 1468 O HOH A 127 56.937 -56.074 -5.893 1.00 59.34 O HETATM 1469 O HOH A 128 58.907 -55.739 -6.761 1.00 53.49 O HETATM 1470 O HOH A 129 63.760 -51.395 4.376 1.00 56.26 O HETATM 1471 O HOH A 130 57.234 -54.690 8.157 1.00 56.80 O HETATM 1472 O HOH A 131 39.085 -39.921 8.807 1.00 55.39 O HETATM 1473 O HOH A 132 54.909 -53.983 8.334 1.00 52.37 O HETATM 1474 O HOH A 133 37.410 -43.455 4.873 1.00 48.23 O HETATM 1475 O HOH A 134 52.271 -51.564 9.849 1.00 45.30 O HETATM 1476 O HOH A 135 56.973 -57.295 4.826 1.00 59.35 O HETATM 1477 O HOH A 136 52.833 -48.372 13.786 1.00 50.27 O HETATM 1478 O HOH A 137 42.807 -67.122 10.628 1.00 63.73 O HETATM 1479 O HOH A 138 39.481 -42.838 6.648 1.00 57.82 O HETATM 1480 O HOH B 101 44.698 -60.732 16.036 1.00 46.79 O HETATM 1481 O HOH B 102 28.212 -61.581 16.201 1.00 55.79 O HETATM 1482 O HOH B 103 41.688 -58.008 13.829 1.00 42.63 O HETATM 1483 O HOH B 104 39.901 -59.102 17.182 1.00 38.37 O HETATM 1484 O HOH B 105 65.612 -49.500 -8.012 1.00 48.05 O HETATM 1485 O HOH B 106 36.655 -55.896 17.985 1.00 41.46 O HETATM 1486 O HOH B 107 62.870 -42.874 -6.680 1.00 44.22 O HETATM 1487 O HOH B 108 41.955 -59.679 20.615 1.00 41.80 O HETATM 1488 O HOH B 109 57.737 -47.794 -8.423 1.00 36.50 O HETATM 1489 O HOH B 110 36.232 -57.090 20.551 1.00 39.11 O HETATM 1490 O HOH B 111 29.899 -61.642 9.087 1.00 59.25 O HETATM 1491 O HOH B 112 37.945 -58.927 21.713 1.00 48.41 O HETATM 1492 O HOH B 113 55.551 -44.423 -10.318 1.00 53.09 O HETATM 1493 O HOH B 114 75.490 -60.973 0.375 1.00 49.54 O HETATM 1494 O HOH B 115 62.472 -48.177 -10.416 1.00 29.54 O HETATM 1495 O HOH B 116 43.499 -61.970 20.203 1.00 42.79 O HETATM 1496 O HOH B 117 33.283 -58.804 10.263 1.00 40.94 O HETATM 1497 O HOH B 118 39.575 -56.829 12.243 1.00 48.62 O HETATM 1498 O HOH B 119 47.008 -56.017 8.961 1.00 54.45 O HETATM 1499 O HOH B 120 37.070 -63.021 23.468 1.00 69.01 O HETATM 1500 O HOH B 121 45.210 -46.002 -9.542 1.00 56.09 O HETATM 1501 O HOH B 122 38.284 -56.871 16.200 1.00 38.13 O HETATM 1502 O HOH B 123 43.797 -49.024 -0.138 1.00 25.21 O HETATM 1503 O HOH B 124 49.901 -53.086 -3.405 1.00 30.92 O HETATM 1504 O HOH B 125 53.921 -54.152 -2.849 1.00 42.07 O HETATM 1505 O HOH B 126 57.984 -41.597 -3.862 1.00 37.90 O HETATM 1506 O HOH B 127 52.647 -48.523 -8.284 1.00 51.46 O HETATM 1507 O HOH B 128 56.565 -51.785 -6.985 1.00 37.76 O HETATM 1508 O HOH B 129 64.786 -49.905 0.179 1.00 36.45 O HETATM 1509 O HOH B 130 55.277 -48.711 -7.482 1.00 36.10 O HETATM 1510 O HOH B 131 31.769 -57.146 12.494 1.00 66.45 O HETATM 1511 O HOH B 132 56.528 -54.033 -4.944 1.00 42.74 O HETATM 1512 O HOH B 133 43.659 -61.702 5.021 1.00 41.52 O HETATM 1513 O HOH B 134 43.500 -65.081 9.412 1.00 55.28 O HETATM 1514 O HOH B 135 63.427 -53.661 -8.204 1.00 42.25 O HETATM 1515 O HOH B 136 50.789 -54.423 -0.247 1.00 40.92 O HETATM 1516 O HOH B 137 63.642 -45.745 -1.930 1.00 58.46 O HETATM 1517 O HOH B 138 50.870 -58.611 1.896 1.00 54.50 O HETATM 1518 O HOH B 139 36.192 -57.494 14.633 1.00 50.50 O HETATM 1519 O HOH B 140 50.565 -58.600 4.253 1.00 48.65 O HETATM 1520 O HOH B 141 36.710 -57.676 12.172 1.00 55.47 O MASTER 537 0 0 3 0 0 0 6 1517 3 0 11 END
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Related entries of code: 4y60
Entries with 90% protein sequence similarity cutoff in PDBbind
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Complexes with the same small molecule ligand
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Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
4y60
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Transcription factor SOX18-HMG box
Ligand Name
PROX1-DNA
EC.Number
E.C.-.-.-.-
Resolution
1.75(Å)
Affinity (Kd/Ki/IC50)
Kd=6.1nM
Release Year
2016
Protein/NA Sequence
Check fasta file
Primary Reference
(2016) Nucleic Acids Res. Vol. 44: pp. 3922-3935
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P43680
Entrez Gene ID
NCBI Entrez Gene ID:
20672
ASD
Information of known allosteric effects of PDB entries
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