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Related entries of code: 5am6
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1agwRCSB PDB    PDBbind310aa, >1AGW_1|Chains... at 99%
1fgiRCSB PDB    PDBbind310aa, >1FGI_1|Chains... at 99%
2fgiRCSB PDB    PDBbind310aa, >2FGI_1|Chains... at 99%
3c4fRCSB PDB    PDBbind302aa, >3C4F_1|Chains... at 99%
3rhxRCSB PDB    PDBbind306aa, >3RHX_1|Chains... at 99%
4f63RCSB PDB    PDBbind309aa, >4F63_1|Chains... at 99%
4f64RCSB PDB    PDBbind309aa, >4F64_1|Chains... at 99%
4f65RCSB PDB    PDBbind309aa, >4F65_1|Chains... at 99%
4nk9RCSB PDB    PDBbind309aa, >4NK9_1|Chains... at 99%
4nkaRCSB PDB    PDBbind309aa, >4NKA_1|Chains... at 99%
4nksRCSB PDB    PDBbind309aa, >4NKS_1|Chains... at 99%
4rwjRCSB PDB    PDBbind317aa, >4RWJ_1|Chains... at 96%
4rwkRCSB PDB    PDBbind317aa, >4RWK_1|Chains... at 96%
4rwlRCSB PDB    PDBbind317aa, >4RWL_1|Chains... at 96%
4v01RCSB PDB    PDBbind309aa, >4V01_1|Chains... at 99%
4v04RCSB PDB    PDBbind309aa, >4V04_1|Chains... at 99%
4v05RCSB PDB    PDBbind309aa, >4V05_1|Chains... at 99%
4zsaRCSB PDB    PDBbind308aa, >4ZSA_1|Chains... at 99%
5a46RCSB PDB    PDBbind386aa, >5A46_1|Chains... *
5a4cRCSB PDB    PDBbind307aa, >5A4C_1|Chains... at 99%
5am7RCSB PDB    PDBbind310aa, >5AM7_1|Chains... at 98%
5ur1RCSB PDB    PDBbind311aa, >5UR1_1|Chains... at 98%
5vndRCSB PDB    PDBbind309aa, >5VND_1|Chains... at 98%
6nvlRCSB PDB    PDBbind309aa, >6NVL_1|Chains... at 99%
6mzwRCSB PDB    PDBbind311aa, >6MZW_1|Chains... at 98%
6mzqRCSB PDB    PDBbind311aa, >6MZQ_1|Chains... at 98%
6itjRCSB PDB    PDBbind308aa, >6ITJ_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5a46RCSB PDB    PDBbind38O
5am7RCSB PDB    PDBbind38O
Entry Information
PDB ID5am6
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameFibroblast growth factor receptors (FGFR1-2c)
Ligand Name38O
EC.Number E.C.2.7.10.1
Resolution 1.96(Å)
Affinity (Kd/Ki/IC50)Kd=185nM
Release Year2015
Protein/NA SequenceCheck fasta file
Primary Reference (2015) Ebiomedicine Vol. 2: pp. 194-204
Ligand Properties
Formula C21H22FN6O
Molecular Weight 393.437
Exact Mass 393.184
No. of atoms 51
No. of bonds 55
Polar Surface Area 95.24
LOGP Value 1.64      (Computed with XLOGP3)
3.34      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P11362  
Entrez Gene IDNCBI Entrez Gene ID: 2260  
ASDInformation of known allosteric effects of PDB entries
 
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