Browse entries in the PDBbind-CN Database
HEADER RNA BINDING PROTEIN/RNA 10-SEP-15 5DNO TITLE CRYSTAL STRUCTURE OF MMI1 YTH DOMAIN COMPLEX WITH RNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: YTH DOMAIN-CONTAINING PROTEIN MMI1; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: UNP RESIDUES 322-488; COMPND 5 SYNONYM: MEIOTIC MRNA INTERCEPTION PROTEIN 1; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'); COMPND 9 CHAIN: B; COMPND 10 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE 972H-; SOURCE 3 ORGANISM_COMMON: FISSION YEAST; SOURCE 4 ORGANISM_TAXID: 284812; SOURCE 5 STRAIN: 972; SOURCE 6 ATCC: 24843; SOURCE 7 GENE: MMI1, SPCC736.12C; SOURCE 8 EXPRESSION_SYSTEM: ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG'; SOURCE 9 EXPRESSION_SYSTEM_TAXID: 866768; SOURCE 10 EXPRESSION_SYSTEM_STRAIN: BL21-GOLD(DE3)PLYSS AG; SOURCE 11 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 12 MOL_ID: 2; SOURCE 13 SYNTHETIC: YES; SOURCE 14 ORGANISM_SCIENTIFIC: SCHIZOSACCHAROMYCES POMBE 972H-; SOURCE 15 ORGANISM_TAXID: 284812 KEYWDS RNA-PROTEIN COMPLEX, RNA BINDING PROTEIN-RNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR C.Y.WANG,Y.W.ZHU,J.H.WU,Y.Y.SHI REVDAT 1 06-APR-16 5DNO 0 JRNL AUTH C.Y.WANG,Y.W.ZHU,H.Y.BAO,Y.Y.JIANG,C.XU,J.H.WU,Y.Y.SHI JRNL TITL A NOVEL RNA-BINDING MODE OF THE YTH DOMAIN REVEALS THE JRNL TITL 2 MECHANISM FOR RECOGNITION OF DETERMINANT OF SELECTIVE JRNL TITL 3 REMOVAL BY MMI1 JRNL REF NUCLEIC ACIDS RES. V. 44 969 2016 JRNL REFN ESSN 1362-4962 JRNL PMID 26673708 JRNL DOI 10.1093/NAR/GKV1382 REMARK 2 REMARK 2 RESOLUTION. 1.80 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.8.0103 REMARK 3 AUTHORS : MURSHUDOV,VAGIN,DODSON REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.80 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 38.76 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 99.9 REMARK 3 NUMBER OF REFLECTIONS : 19833 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.178 REMARK 3 R VALUE (WORKING SET) : 0.176 REMARK 3 FREE R VALUE : 0.216 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.200 REMARK 3 FREE R VALUE TEST SET COUNT : 1084 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 1.80 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 1.84 REMARK 3 REFLECTION IN BIN (WORKING SET) : 1469 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 99.55 REMARK 3 BIN R VALUE (WORKING SET) : 0.2250 REMARK 3 BIN FREE R VALUE SET COUNT : 72 REMARK 3 BIN FREE R VALUE : 0.2560 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 1304 REMARK 3 NUCLEIC ACID ATOMS : 143 REMARK 3 HETEROGEN ATOMS : 0 REMARK 3 SOLVENT ATOMS : 116 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 14.06 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : 0.21000 REMARK 3 B22 (A**2) : 0.21000 REMARK 3 B33 (A**2) : -0.67000 REMARK 3 B12 (A**2) : 0.10000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.168 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.111 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.085 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 6.392 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.931 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.902 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1487 ; 0.008 ; 0.018 REMARK 3 BOND LENGTHS OTHERS (A): 1317 ; 0.002 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 2029 ; 1.277 ; 1.855 REMARK 3 BOND ANGLES OTHERS (DEGREES): 3030 ; 1.428 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 162 ; 6.472 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 60 ;33.838 ;22.500 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 241 ;11.506 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 12 ;14.991 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 222 ; 0.082 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1561 ; 0.005 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): 354 ; 0.001 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 656 ; 0.844 ; 1.178 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 655 ; 0.815 ; 1.175 REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 816 ; 1.080 ; 1.752 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): 2803 ; 2.414 ; 3.000 REMARK 3 SPHERICITY; FREE ATOMS (A**2): 37 ;33.342 ; 5.000 REMARK 3 SPHERICITY; BONDED ATOMS (A**2): 2842 ; 5.267 ; 5.000 REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS U VALUES : REFINED INDIVIDUALLY REMARK 4 REMARK 4 5DNO COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 13-SEP-15. REMARK 100 THE DEPOSITION ID IS D_1000213493. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 15-MAY-15 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 6.0 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRF REMARK 200 BEAMLINE : BL17U REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9795 REMARK 200 MONOCHROMATOR : SI 111 DOUBLE CRYSTAL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : ADSC QUANTUM 315R REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 20848 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.800 REMARK 200 RESOLUTION RANGE LOW (A) : 38.760 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.9 REMARK 200 DATA REDUNDANCY : 11.50 REMARK 200 R MERGE (I) : 0.14900 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 25.4000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.80 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.86 REMARK 200 COMPLETENESS FOR SHELL (%) : 99.6 REMARK 200 DATA REDUNDANCY IN SHELL : 11.50 REMARK 200 R MERGE FOR SHELL (I) : 0.60200 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: MOLREP REMARK 200 STARTING MODEL: 4R3I REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 51.33 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.53 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 100 MM MES, 18% (W/V) PEG 2000, PH REMARK 280 6.0, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 65 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+2/3 REMARK 290 3555 -X+Y,-X,Z+1/3 REMARK 290 4555 -X,-Y,Z+1/2 REMARK 290 5555 Y,-X+Y,Z+1/6 REMARK 290 6555 X-Y,X,Z+5/6 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 43.68600 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 21.84300 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 32.76450 REMARK 290 SMTRY1 5 0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 5 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 10.92150 REMARK 290 SMTRY1 6 0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 54.60750 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 1240 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 9490 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -5.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 311 REMARK 465 GLY A 312 REMARK 465 SER A 313 REMARK 465 SER A 314 REMARK 465 HIS A 315 REMARK 465 HIS A 316 REMARK 465 HIS A 317 REMARK 465 HIS A 318 REMARK 465 HIS A 319 REMARK 465 ASN A 326 REMARK 465 GLU A 327 REMARK 465 LYS A 328 REMARK 465 GLY A 329 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 ALA A 320 N CA CB REMARK 470 GLU A 360 CG CD OE1 OE2 REMARK 470 LYS A 388 CD CE NZ REMARK 470 GLN A 399 CD OE1 NE2 REMARK 470 ASN A 439 ND2 REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 HOH A 606 DISTANCE = 6.94 ANGSTROMS REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5DNP RELATED DB: PDB DBREF 5DNO A 322 488 UNP O74958 MMI1_SCHPO 322 488 DBREF 5DNO B 1 7 PDB 5DNO 5DNO 1 7 SEQADV 5DNO MET A 311 UNP O74958 EXPRESSION TAG SEQADV 5DNO GLY A 312 UNP O74958 EXPRESSION TAG SEQADV 5DNO SER A 313 UNP O74958 EXPRESSION TAG SEQADV 5DNO SER A 314 UNP O74958 EXPRESSION TAG SEQADV 5DNO HIS A 315 UNP O74958 EXPRESSION TAG SEQADV 5DNO HIS A 316 UNP O74958 EXPRESSION TAG SEQADV 5DNO HIS A 317 UNP O74958 EXPRESSION TAG SEQADV 5DNO HIS A 318 UNP O74958 EXPRESSION TAG SEQADV 5DNO HIS A 319 UNP O74958 EXPRESSION TAG SEQADV 5DNO ALA A 320 UNP O74958 EXPRESSION TAG SEQADV 5DNO MET A 321 UNP O74958 EXPRESSION TAG SEQRES 1 A 178 MET GLY SER SER HIS HIS HIS HIS HIS ALA MET SER GLU SEQRES 2 A 178 HIS ARG ASN GLU LYS GLY GLU ARG ILE SER MET ILE ASN SEQRES 3 A 178 PRO ARG VAL VAL LEU ASP GLU ASN GLY ILE SER HIS ARG SEQRES 4 A 178 SER ARG TYR PHE ILE MET LEU CYS ASP ASN GLU THR ALA SEQRES 5 A 178 ILE ALA HIS ALA LYS LYS THR SER ILE TRP ALA VAL LYS SEQRES 6 A 178 LYS ASP SER SER LYS ARG ILE SER ASP ALA TYR LYS LYS SEQRES 7 A 178 ALA SER VAL TYR PHE ILE PHE VAL ALA GLN GLN THR TYR SEQRES 8 A 178 ASN ALA LEU GLY TYR ALA GLN VAL VAL SER ASP LEU ASN SEQRES 9 A 178 SER THR GLU LEU PRO PHE TRP SER ASP SER SER HIS ALA SEQRES 10 A 178 GLY GLY VAL ARG ILE LYS TRP ILE LYS THR CYS ASN LEU SEQRES 11 A 178 PHE SER ALA GLU ILE SER GLU ILE VAL SER HIS MET ASP SEQRES 12 A 178 HIS GLY SER GLU ALA ARG ASP GLY MET GLU MET MET TYR SEQRES 13 A 178 ASP GLU GLY SER ARG LEU CYS THR LEU ILE ASN TYR ALA SEQRES 14 A 178 ILE MET LYS ARG ILE GLY ARG ASP ARG SEQRES 1 B 7 C U U A A A C FORMUL 3 HOH *116(H2 O) HELIX 1 AA1 ASN A 359 SER A 370 1 12 HELIX 2 AA2 LYS A 376 ALA A 389 1 14 HELIX 3 AA3 SER A 442 HIS A 451 1 10 HELIX 4 AA4 MET A 465 LYS A 482 1 18 SHEET 1 AA1 6 ILE A 371 LYS A 375 0 SHEET 2 AA1 6 HIS A 426 LEU A 440 -1 O ALA A 427 N VAL A 374 SHEET 3 AA1 6 ALA A 403 VAL A 409 -1 N ALA A 403 O LEU A 440 SHEET 4 AA1 6 SER A 390 ALA A 397 -1 N PHE A 395 O LEU A 404 SHEET 5 AA1 6 SER A 350 CYS A 357 1 N CYS A 357 O VAL A 396 SHEET 6 AA1 6 GLU A 463 MET A 464 -1 O MET A 464 N TYR A 352 CRYST1 77.527 77.527 65.529 90.00 90.00 120.00 P 65 6 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.012899 0.007447 0.000000 0.00000 SCALE2 0.000000 0.014894 0.000000 0.00000 SCALE3 0.000000 0.000000 0.015260 0.00000 ATOM 1 C ALA A 320 51.973 -22.031 -15.975 1.00 28.95 C ANISOU 1 C ALA A 320 2676 4400 3922 787 -20 -231 C ATOM 2 O ALA A 320 51.813 -21.468 -17.060 1.00 31.44 O ANISOU 2 O ALA A 320 3084 5204 3654 835 214 -273 O ATOM 3 N MET A 321 52.794 -21.567 -15.041 1.00 28.51 N ANISOU 3 N MET A 321 3593 3640 3597 241 94 -107 N ATOM 4 CA MET A 321 53.303 -20.191 -15.092 1.00 27.85 C ANISOU 4 CA MET A 321 3241 3681 3659 283 16 0 C ATOM 5 C MET A 321 54.446 -20.012 -16.086 1.00 25.33 C ANISOU 5 C MET A 321 3187 2971 3466 247 -75 -42 C ATOM 6 O MET A 321 54.977 -20.979 -16.649 1.00 24.98 O ANISOU 6 O MET A 321 3552 1995 3941 -326 12 -51 O ATOM 7 CB MET A 321 53.758 -19.719 -13.710 1.00 29.03 C ANISOU 7 CB MET A 321 3582 3784 3662 551 23 -178 C ATOM 8 CG MET A 321 55.032 -20.379 -13.196 1.00 28.98 C ANISOU 8 CG MET A 321 3406 3907 3696 450 66 -81 C ATOM 9 SD MET A 321 55.234 -20.145 -11.437 1.00 27.94 S ANISOU 9 SD MET A 321 3426 3451 3735 569 405 -548 S ATOM 10 CE MET A 321 53.784 -21.008 -10.818 1.00 31.15 C ANISOU 10 CE MET A 321 3883 3720 4230 208 227 -113 C ATOM 11 N SER A 322 54.809 -18.746 -16.281 1.00 23.58 N ANISOU 11 N SER A 322 2736 3067 3156 126 -134 -9 N ATOM 12 CA SER A 322 55.931 -18.377 -17.117 1.00 22.42 C ANISOU 12 CA SER A 322 2703 2728 3085 111 -250 122 C ATOM 13 C SER A 322 57.200 -19.002 -16.568 1.00 22.35 C ANISOU 13 C SER A 322 2737 2821 2932 188 -166 159 C ATOM 14 O SER A 322 57.454 -18.936 -15.363 1.00 23.49 O ANISOU 14 O SER A 322 2591 3498 2834 312 53 -60 O ATOM 15 CB SER A 322 56.103 -16.860 -17.144 1.00 22.26 C ANISOU 15 CB SER A 322 2712 2613 3133 382 -8 190 C ATOM 16 OG SER A 322 57.243 -16.504 -17.905 1.00 22.80 O ANISOU 16 OG SER A 322 2650 2488 3523 650 73 520 O ATOM 17 N GLU A 323 57.976 -19.616 -17.453 1.00 22.64 N ANISOU 17 N GLU A 323 2980 2898 2721 68 -3 199 N ATOM 18 CA GLU A 323 59.319 -20.052 -17.120 1.00 25.06 C ANISOU 18 CA GLU A 323 3053 3199 3268 327 134 -59 C ATOM 19 C GLU A 323 60.358 -19.154 -17.812 1.00 27.15 C ANISOU 19 C GLU A 323 3394 3449 3470 252 311 98 C ATOM 20 O GLU A 323 61.537 -19.526 -17.927 1.00 30.34 O ANISOU 20 O GLU A 323 3765 3736 4024 844 376 -89 O ATOM 21 CB GLU A 323 59.483 -21.531 -17.484 1.00 25.03 C ANISOU 21 CB GLU A 323 3316 2963 3231 24 18 241 C ATOM 22 CG GLU A 323 58.548 -22.467 -16.717 1.00 25.62 C ANISOU 22 CG GLU A 323 3203 3356 3174 10 28 343 C ATOM 23 CD GLU A 323 58.847 -22.557 -15.220 1.00 26.95 C ANISOU 23 CD GLU A 323 3293 3733 3213 -501 64 471 C ATOM 24 OE1 GLU A 323 59.884 -22.029 -14.745 1.00 24.48 O ANISOU 24 OE1 GLU A 323 2997 3146 3157 -216 -113 1134 O ATOM 25 OE2 GLU A 323 58.030 -23.152 -14.485 1.00 29.38 O ANISOU 25 OE2 GLU A 323 4121 3703 3339 -1208 -45 615 O ATOM 26 N HIS A 324 59.933 -17.954 -18.227 1.00 25.70 N ANISOU 26 N HIS A 324 3218 3542 3001 298 201 47 N ATOM 27 CA HIS A 324 60.847 -16.957 -18.776 1.00 26.29 C ANISOU 27 CA HIS A 324 3162 3357 3470 21 -100 -217 C ATOM 28 C HIS A 324 61.726 -16.420 -17.647 1.00 26.73 C ANISOU 28 C HIS A 324 3253 3714 3189 62 75 -355 C ATOM 29 O HIS A 324 61.331 -16.444 -16.475 1.00 22.89 O ANISOU 29 O HIS A 324 2317 3130 3248 365 127 -207 O ATOM 30 CB HIS A 324 60.091 -15.806 -19.468 1.00 26.93 C ANISOU 30 CB HIS A 324 3367 3508 3354 -42 -50 -12 C ATOM 31 CG HIS A 324 59.560 -16.155 -20.826 1.00 27.30 C ANISOU 31 CG HIS A 324 3350 3603 3419 -263 -179 159 C ATOM 32 ND1 HIS A 324 58.639 -17.162 -21.037 1.00 26.76 N ANISOU 32 ND1 HIS A 324 3998 2849 3320 -190 -120 150 N ATOM 33 CD2 HIS A 324 59.817 -15.622 -22.044 1.00 26.93 C ANISOU 33 CD2 HIS A 324 3241 3487 3501 -169 -64 176 C ATOM 34 CE1 HIS A 324 58.354 -17.233 -22.325 1.00 25.79 C ANISOU 34 CE1 HIS A 324 3753 2743 3302 110 -112 -54 C ATOM 35 NE2 HIS A 324 59.061 -16.315 -22.959 1.00 27.02 N ANISOU 35 NE2 HIS A 324 3458 3431 3375 0 -112 80 N ATOM 36 N ARG A 325 62.927 -15.971 -18.022 1.00 28.09 N ANISOU 36 N ARG A 325 3380 3604 3688 -7 232 -345 N ATOM 37 CA ARG A 325 63.933 -15.457 -17.086 1.00 28.03 C ANISOU 37 CA ARG A 325 3042 3828 3779 37 182 30 C ATOM 38 C ARG A 325 64.570 -14.195 -17.647 1.00 32.34 C ANISOU 38 C ARG A 325 3182 4446 4659 -191 342 549 C ATOM 39 O ARG A 325 64.838 -14.116 -18.849 1.00 36.50 O ANISOU 39 O ARG A 325 3509 5814 4542 217 133 509 O ATOM 40 CB ARG A 325 65.013 -16.504 -16.847 1.00 27.68 C ANISOU 40 CB ARG A 325 3300 3651 3564 -105 1 440 C ATOM 41 CG ARG A 325 64.507 -17.785 -16.203 1.00 26.82 C ANISOU 41 CG ARG A 325 3366 3540 3285 -133 73 229 C ATOM 42 CD ARG A 325 64.268 -17.575 -14.723 1.00 26.83 C ANISOU 42 CD ARG A 325 3504 3442 3246 -177 218 314 C ATOM 43 NE ARG A 325 63.446 -18.628 -14.123 1.00 27.09 N ANISOU 43 NE ARG A 325 3500 3435 3358 -271 154 287 N ATOM 44 CZ ARG A 325 63.392 -18.903 -12.818 1.00 26.60 C ANISOU 44 CZ ARG A 325 3483 3358 3265 -336 375 114 C ATOM 45 NH1 ARG A 325 64.129 -18.226 -11.935 1.00 26.28 N ANISOU 45 NH1 ARG A 325 3594 3215 3174 -384 683 -63 N ATOM 46 NH2 ARG A 325 62.601 -19.883 -12.387 1.00 28.40 N ANISOU 46 NH2 ARG A 325 3945 3192 3651 -423 184 360 N ATOM 47 N GLU A 330 65.870 -14.135 -12.762 1.00 35.54 N ANISOU 47 N GLU A 330 3508 5912 4083 -300 -288 -127 N ATOM 48 CA GLU A 330 64.654 -14.417 -11.984 1.00 33.36 C ANISOU 48 CA GLU A 330 3491 4965 4219 -246 -416 19 C ATOM 49 C GLU A 330 63.405 -14.521 -12.866 1.00 28.75 C ANISOU 49 C GLU A 330 3067 4102 3753 191 -67 367 C ATOM 50 O GLU A 330 63.429 -14.141 -14.036 1.00 29.02 O ANISOU 50 O GLU A 330 2869 4599 3558 248 -352 141 O ATOM 51 CB GLU A 330 64.462 -13.367 -10.886 1.00 37.04 C ANISOU 51 CB GLU A 330 4302 5023 4746 -21 -81 -191 C ATOM 52 CG GLU A 330 64.374 -11.927 -11.382 1.00 39.55 C ANISOU 52 CG GLU A 330 4760 5291 4974 115 -190 244 C ATOM 53 CD GLU A 330 64.679 -10.895 -10.307 1.00 41.21 C ANISOU 53 CD GLU A 330 4566 5501 5592 29 -200 -80 C ATOM 54 OE1 GLU A 330 64.962 -9.737 -10.673 1.00 45.21 O ANISOU 54 OE1 GLU A 330 4580 5677 6919 -117 -178 88 O ATOM 55 OE2 GLU A 330 64.640 -11.225 -9.102 1.00 44.48 O ANISOU 55 OE2 GLU A 330 5119 6312 5466 -21 -938 -197 O ATOM 56 N ARG A 331 62.325 -15.050 -12.296 1.00 22.39 N ANISOU 56 N ARG A 331 2660 2944 2902 304 -663 154 N ATOM 57 CA ARG A 331 61.124 -15.373 -13.063 1.00 19.70 C ANISOU 57 CA ARG A 331 2221 2484 2777 276 -177 114 C ATOM 58 C ARG A 331 60.408 -14.121 -13.503 1.00 18.12 C ANISOU 58 C ARG A 331 1830 2423 2632 157 -243 74 C ATOM 59 O ARG A 331 60.145 -13.242 -12.688 1.00 15.97 O ANISOU 59 O ARG A 331 1310 2088 2667 468 -169 367 O ATOM 60 CB ARG A 331 60.163 -16.214 -12.246 1.00 20.54 C ANISOU 60 CB ARG A 331 2554 2570 2678 134 26 66 C ATOM 61 CG ARG A 331 59.009 -16.783 -13.070 1.00 21.08 C ANISOU 61 CG ARG A 331 2704 2818 2485 60 52 104 C ATOM 62 CD ARG A 331 58.056 -17.567 -12.198 1.00 22.41 C ANISOU 62 CD ARG A 331 2861 2861 2791 -61 110 146 C ATOM 63 NE ARG A 331 58.769 -18.605 -11.467 1.00 23.45 N ANISOU 63 NE ARG A 331 3219 2879 2811 126 155 172 N ATOM 64 CZ ARG A 331 59.174 -19.768 -11.980 1.00 23.38 C ANISOU 64 CZ ARG A 331 3205 3052 2627 88 101 -30 C ATOM 65 NH1 ARG A 331 58.933 -20.077 -13.247 1.00 23.24 N ANISOU 65 NH1 ARG A 331 2910 3357 2564 -102 -68 195 N ATOM 66 NH2 ARG A 331 59.829 -20.645 -11.214 1.00 23.30 N ANISOU 66 NH2 ARG A 331 3453 2737 2662 -5 197 113 N ATOM 67 N ILE A 332 60.058 -14.083 -14.785 1.00 18.09 N ANISOU 67 N ILE A 332 1924 2362 2588 275 -38 154 N ATOM 68 CA ILE A 332 59.410 -12.925 -15.395 1.00 17.90 C ANISOU 68 CA ILE A 332 2101 2256 2443 105 -252 165 C ATOM 69 C ILE A 332 58.186 -13.343 -16.220 1.00 15.97 C ANISOU 69 C ILE A 332 1710 1870 2485 257 -87 290 C ATOM 70 O ILE A 332 58.064 -14.496 -16.665 1.00 12.62 O ANISOU 70 O ILE A 332 1116 1371 2306 487 -426 847 O ATOM 71 CB ILE A 332 60.404 -12.130 -16.280 1.00 20.38 C ANISOU 71 CB ILE A 332 2341 2589 2812 -43 -25 78 C ATOM 72 CG1 ILE A 332 61.050 -13.032 -17.341 1.00 21.37 C ANISOU 72 CG1 ILE A 332 2577 2665 2878 -6 12 -10 C ATOM 73 CG2 ILE A 332 61.472 -11.474 -15.408 1.00 21.05 C ANISOU 73 CG2 ILE A 332 2361 2593 3043 24 -97 -62 C ATOM 74 CD1 ILE A 332 61.905 -12.305 -18.356 1.00 23.33 C ANISOU 74 CD1 ILE A 332 2937 2940 2984 -125 134 54 C ATOM 75 N SER A 333 57.286 -12.390 -16.428 1.00 15.31 N ANISOU 75 N SER A 333 1979 1523 2312 158 -211 427 N ATOM 76 CA SER A 333 56.118 -12.600 -17.292 1.00 15.74 C ANISOU 76 CA SER A 333 1873 1850 2257 70 -63 308 C ATOM 77 C SER A 333 56.550 -12.996 -18.708 1.00 16.35 C ANISOU 77 C SER A 333 1963 1948 2300 250 -44 325 C ATOM 78 O SER A 333 57.596 -12.546 -19.196 1.00 18.87 O ANISOU 78 O SER A 333 2432 2459 2277 9 234 605 O ATOM 79 CB SER A 333 55.238 -11.333 -17.320 1.00 15.78 C ANISOU 79 CB SER A 333 1834 2004 2155 155 -3 218 C ATOM 80 OG SER A 333 54.526 -11.177 -18.538 1.00 14.70 O ANISOU 80 OG SER A 333 1880 1943 1760 149 283 70 O ATOM 81 N MET A 334 55.753 -13.854 -19.342 1.00 16.56 N ANISOU 81 N MET A 334 2107 1638 2547 305 0 252 N ATOM 82 CA MET A 334 55.950 -14.220 -20.748 1.00 19.19 C ANISOU 82 CA MET A 334 2419 2284 2585 239 57 159 C ATOM 83 C MET A 334 55.348 -13.191 -21.728 1.00 19.49 C ANISOU 83 C MET A 334 2722 2113 2570 272 269 225 C ATOM 84 O MET A 334 55.523 -13.318 -22.941 1.00 21.35 O ANISOU 84 O MET A 334 3177 2288 2644 445 320 -25 O ATOM 85 CB MET A 334 55.392 -15.632 -21.026 1.00 21.51 C ANISOU 85 CB MET A 334 2893 2235 3043 264 101 -37 C ATOM 86 CG MET A 334 53.883 -15.747 -21.118 1.00 24.51 C ANISOU 86 CG MET A 334 3063 2843 3407 -77 -23 -92 C ATOM 87 SD MET A 334 53.327 -17.431 -21.419 1.00 32.08 S ANISOU 87 SD MET A 334 3754 3222 5211 -398 71 -789 S ATOM 88 CE MET A 334 53.585 -17.544 -23.192 1.00 37.14 C ANISOU 88 CE MET A 334 4585 4342 5182 -58 20 -125 C ATOM 89 N ILE A 335 54.618 -12.208 -21.205 1.00 18.97 N ANISOU 89 N ILE A 335 2452 2417 2338 345 126 127 N ATOM 90 CA ILE A 335 54.048 -11.117 -21.997 1.00 19.40 C ANISOU 90 CA ILE A 335 2585 2387 2396 381 229 134 C ATOM 91 C ILE A 335 54.948 -9.876 -21.905 1.00 21.00 C ANISOU 91 C ILE A 335 2659 2629 2690 210 350 232 C ATOM 92 O ILE A 335 55.276 -9.280 -22.934 1.00 23.20 O ANISOU 92 O ILE A 335 3190 2904 2720 522 734 227 O ATOM 93 CB ILE A 335 52.600 -10.807 -21.527 1.00 19.12 C ANISOU 93 CB ILE A 335 2242 2505 2515 158 -52 150 C ATOM 94 CG1 ILE A 335 51.701 -12.031 -21.756 1.00 18.43 C ANISOU 94 CG1 ILE A 335 2335 2308 2359 291 -54 150 C ATOM 95 CG2 ILE A 335 52.033 -9.585 -22.251 1.00 19.51 C ANISOU 95 CG2 ILE A 335 2374 2470 2567 45 -41 165 C ATOM 96 CD1 ILE A 335 50.389 -11.971 -21.007 1.00 19.81 C ANISOU 96 CD1 ILE A 335 2277 2584 2666 -44 -45 185 C ATOM 97 N ASN A 336 55.332 -9.491 -20.683 1.00 20.04 N ANISOU 97 N ASN A 336 2367 2648 2599 204 173 564 N ATOM 98 CA ASN A 336 56.218 -8.358 -20.446 1.00 24.40 C ANISOU 98 CA ASN A 336 3038 3047 3185 -79 -138 230 C ATOM 99 C ASN A 336 57.432 -8.770 -19.607 1.00 23.61 C ANISOU 99 C ASN A 336 3314 2862 2794 -328 -229 359 C ATOM 100 O ASN A 336 57.296 -8.967 -18.405 1.00 20.78 O ANISOU 100 O ASN A 336 2779 2237 2880 -882 207 464 O ATOM 101 CB ASN A 336 55.473 -7.216 -19.751 1.00 25.68 C ANISOU 101 CB ASN A 336 3213 3324 3217 141 -170 220 C ATOM 102 CG ASN A 336 56.336 -5.964 -19.576 1.00 26.51 C ANISOU 102 CG ASN A 336 3414 3183 3474 127 -130 406 C ATOM 103 OD1 ASN A 336 57.527 -5.935 -19.914 1.00 27.43 O ANISOU 103 OD1 ASN A 336 3349 3419 3652 722 -299 912 O ATOM 104 ND2 ASN A 336 55.733 -4.925 -19.051 1.00 27.56 N ANISOU 104 ND2 ASN A 336 3374 3360 3737 231 32 338 N ATOM 105 N PRO A 337 58.633 -8.829 -20.225 1.00 27.71 N ANISOU 105 N PRO A 337 3421 3462 3643 -203 50 253 N ATOM 106 CA PRO A 337 59.809 -9.312 -19.497 1.00 28.88 C ANISOU 106 CA PRO A 337 3188 3988 3797 -490 -49 298 C ATOM 107 C PRO A 337 60.238 -8.447 -18.304 1.00 26.92 C ANISOU 107 C PRO A 337 2805 3648 3774 -552 204 416 C ATOM 108 O PRO A 337 60.988 -8.926 -17.452 1.00 28.73 O ANISOU 108 O PRO A 337 2067 4381 4465 -745 71 724 O ATOM 109 CB PRO A 337 60.896 -9.317 -20.573 1.00 31.21 C ANISOU 109 CB PRO A 337 3662 4397 3797 -87 82 51 C ATOM 110 CG PRO A 337 60.503 -8.221 -21.491 1.00 31.91 C ANISOU 110 CG PRO A 337 3811 4270 4044 47 15 49 C ATOM 111 CD PRO A 337 59.009 -8.345 -21.570 1.00 30.50 C ANISOU 111 CD PRO A 337 3889 4046 3652 -176 38 273 C ATOM 112 N ARG A 338 59.774 -7.198 -18.236 1.00 25.57 N ANISOU 112 N ARG A 338 2696 3505 3514 -695 155 482 N ATOM 113 CA ARG A 338 60.073 -6.338 -17.089 1.00 27.73 C ANISOU 113 CA ARG A 338 3292 3673 3569 -512 282 259 C ATOM 114 C ARG A 338 59.260 -6.653 -15.821 1.00 22.52 C ANISOU 114 C ARG A 338 2590 2690 3277 -501 -121 145 C ATOM 115 O ARG A 338 59.585 -6.135 -14.752 1.00 21.31 O ANISOU 115 O ARG A 338 2228 2477 3392 -752 28 111 O ATOM 116 CB ARG A 338 59.928 -4.860 -17.477 1.00 31.80 C ANISOU 116 CB ARG A 338 4114 3728 4240 -464 -195 246 C ATOM 117 CG ARG A 338 60.973 -4.409 -18.493 1.00 35.74 C ANISOU 117 CG ARG A 338 4546 4668 4363 -231 193 234 C ATOM 118 CD ARG A 338 60.721 -2.988 -18.969 1.00 41.20 C ANISOU 118 CD ARG A 338 5557 4785 5309 -230 -353 353 C ATOM 119 NE ARG A 338 59.527 -2.908 -19.813 1.00 44.08 N ANISOU 119 NE ARG A 338 5249 5512 5984 -544 -399 267 N ATOM 120 CZ ARG A 338 59.486 -3.129 -21.130 1.00 48.83 C ANISOU 120 CZ ARG A 338 6201 6341 6009 -139 -215 51 C ATOM 121 NH1 ARG A 338 60.578 -3.454 -21.825 1.00 51.35 N ANISOU 121 NH1 ARG A 338 5968 6977 6563 207 -481 -396 N ATOM 122 NH2 ARG A 338 58.323 -3.025 -21.768 1.00 52.66 N ANISOU 122 NH2 ARG A 338 6410 7142 6455 126 -339 463 N ATOM 123 N VAL A 339 58.235 -7.508 -15.917 1.00 17.70 N ANISOU 123 N VAL A 339 1927 2481 2316 -25 -248 322 N ATOM 124 CA VAL A 339 57.417 -7.852 -14.754 1.00 16.24 C ANISOU 124 CA VAL A 339 1866 1954 2350 -32 -232 246 C ATOM 125 C VAL A 339 57.979 -9.103 -14.090 1.00 15.22 C ANISOU 125 C VAL A 339 1544 1980 2256 -78 -115 303 C ATOM 126 O VAL A 339 57.940 -10.193 -14.667 1.00 13.76 O ANISOU 126 O VAL A 339 1301 1591 2336 -153 -273 643 O ATOM 127 CB VAL A 339 55.934 -8.076 -15.118 1.00 15.64 C ANISOU 127 CB VAL A 339 1846 1954 2142 -4 -177 125 C ATOM 128 CG1 VAL A 339 55.123 -8.385 -13.870 1.00 15.34 C ANISOU 128 CG1 VAL A 339 1887 1873 2068 65 -142 28 C ATOM 129 CG2 VAL A 339 55.376 -6.845 -15.821 1.00 16.01 C ANISOU 129 CG2 VAL A 339 2017 1980 2084 64 -151 103 C ATOM 130 N VAL A 340 58.503 -8.928 -12.883 1.00 15.39 N ANISOU 130 N VAL A 340 1706 1911 2227 -17 -84 256 N ATOM 131 CA VAL A 340 59.111 -10.033 -12.125 1.00 14.98 C ANISOU 131 CA VAL A 340 1723 1717 2249 -62 19 244 C ATOM 132 C VAL A 340 57.998 -10.716 -11.343 1.00 13.50 C ANISOU 132 C VAL A 340 1597 1506 2025 57 -3 123 C ATOM 133 O VAL A 340 57.193 -10.055 -10.725 1.00 12.50 O ANISOU 133 O VAL A 340 1356 1114 2276 5 -15 253 O ATOM 134 CB VAL A 340 60.211 -9.546 -11.158 1.00 16.45 C ANISOU 134 CB VAL A 340 2024 2043 2183 -45 -99 149 C ATOM 135 CG1 VAL A 340 60.914 -10.731 -10.501 1.00 17.81 C ANISOU 135 CG1 VAL A 340 2413 1963 2390 -24 -192 159 C ATOM 136 CG2 VAL A 340 61.244 -8.707 -11.896 1.00 16.66 C ANISOU 136 CG2 VAL A 340 1966 2038 2324 -83 -94 141 C ATOM 137 N LEU A 341 57.982 -12.044 -11.363 1.00 12.88 N ANISOU 137 N LEU A 341 1411 1488 1994 -4 -98 131 N ATOM 138 CA LEU A 341 56.899 -12.832 -10.772 1.00 12.29 C ANISOU 138 CA LEU A 341 1471 1500 1698 -3 -121 107 C ATOM 139 C LEU A 341 57.416 -13.652 -9.606 1.00 13.15 C ANISOU 139 C LEU A 341 1607 1539 1850 32 -220 162 C ATOM 140 O LEU A 341 58.601 -13.974 -9.555 1.00 14.76 O ANISOU 140 O LEU A 341 1563 1755 2287 -67 -551 449 O ATOM 141 CB LEU A 341 56.320 -13.768 -11.832 1.00 12.10 C ANISOU 141 CB LEU A 341 1452 1489 1656 -5 -58 76 C ATOM 142 CG LEU A 341 55.823 -13.129 -13.136 1.00 11.68 C ANISOU 142 CG LEU A 341 1444 1433 1561 -52 32 79 C ATOM 143 CD1 LEU A 341 55.393 -14.213 -14.126 1.00 12.60 C ANISOU 143 CD1 LEU A 341 1580 1647 1561 -43 7 -24 C ATOM 144 CD2 LEU A 341 54.676 -12.199 -12.830 1.00 11.24 C ANISOU 144 CD2 LEU A 341 1451 1317 1502 -75 7 135 C ATOM 145 N ASP A 342 56.533 -13.980 -8.666 1.00 12.74 N ANISOU 145 N ASP A 342 1561 1575 1703 -115 -371 117 N ATOM 146 CA ASP A 342 56.891 -14.917 -7.594 1.00 13.07 C ANISOU 146 CA ASP A 342 1741 1500 1722 -12 -279 81 C ATOM 147 C ASP A 342 56.787 -16.358 -8.124 1.00 12.34 C ANISOU 147 C ASP A 342 1619 1454 1613 53 -204 133 C ATOM 148 O ASP A 342 56.597 -16.575 -9.322 1.00 10.50 O ANISOU 148 O ASP A 342 1592 793 1605 29 -276 298 O ATOM 149 CB ASP A 342 56.063 -14.638 -6.323 1.00 14.81 C ANISOU 149 CB ASP A 342 1976 1917 1734 35 -282 -205 C ATOM 150 CG ASP A 342 54.625 -15.121 -6.410 1.00 16.49 C ANISOU 150 CG ASP A 342 1953 2400 1909 66 -435 -318 C ATOM 151 OD1 ASP A 342 54.206 -15.601 -7.482 1.00 16.65 O ANISOU 151 OD1 ASP A 342 1982 2544 1799 203 -382 -374 O ATOM 152 OD2 ASP A 342 53.903 -15.032 -5.384 1.00 21.65 O ANISOU 152 OD2 ASP A 342 2765 3677 1783 607 -474 -1090 O ATOM 153 N GLU A 343 56.904 -17.341 -7.239 1.00 12.06 N ANISOU 153 N GLU A 343 1647 1399 1534 133 -178 67 N ATOM 154 CA GLU A 343 56.893 -18.751 -7.646 1.00 11.54 C ANISOU 154 CA GLU A 343 1428 1424 1530 -11 -93 22 C ATOM 155 C GLU A 343 55.481 -19.317 -7.875 1.00 11.00 C ANISOU 155 C GLU A 343 1327 1399 1454 57 8 92 C ATOM 156 O GLU A 343 55.331 -20.494 -8.145 1.00 11.18 O ANISOU 156 O GLU A 343 1234 1397 1617 71 60 73 O ATOM 157 CB GLU A 343 57.684 -19.583 -6.635 1.00 11.75 C ANISOU 157 CB GLU A 343 1543 1378 1542 67 32 96 C ATOM 158 CG GLU A 343 59.164 -19.216 -6.618 1.00 12.79 C ANISOU 158 CG GLU A 343 1575 1491 1794 56 100 191 C ATOM 159 CD GLU A 343 59.821 -19.380 -7.984 1.00 14.08 C ANISOU 159 CD GLU A 343 1803 1554 1993 87 325 122 C ATOM 160 OE1 GLU A 343 60.255 -18.367 -8.576 1.00 15.88 O ANISOU 160 OE1 GLU A 343 1932 1673 2429 198 732 290 O ATOM 161 OE2 GLU A 343 59.860 -20.516 -8.504 1.00 14.05 O ANISOU 161 OE2 GLU A 343 1937 1382 2019 60 296 268 O ATOM 162 N ASN A 344 54.472 -18.461 -7.754 1.00 10.68 N ANISOU 162 N ASN A 344 1292 1368 1396 42 -40 69 N ATOM 163 CA ASN A 344 53.097 -18.710 -8.219 1.00 10.02 C ANISOU 163 CA ASN A 344 1290 1234 1280 -8 -17 73 C ATOM 164 C ASN A 344 52.725 -17.907 -9.481 1.00 9.31 C ANISOU 164 C ASN A 344 1137 1162 1239 11 20 24 C ATOM 165 O ASN A 344 51.572 -17.915 -9.910 1.00 8.55 O ANISOU 165 O ASN A 344 1106 1015 1128 32 66 72 O ATOM 166 CB ASN A 344 52.134 -18.348 -7.091 1.00 10.18 C ANISOU 166 CB ASN A 344 1294 1271 1300 -6 -2 100 C ATOM 167 CG ASN A 344 52.433 -19.109 -5.819 1.00 10.28 C ANISOU 167 CG ASN A 344 1336 1254 1313 84 -13 81 C ATOM 168 OD1 ASN A 344 52.063 -20.265 -5.697 1.00 9.65 O ANISOU 168 OD1 ASN A 344 1357 1074 1234 393 249 124 O ATOM 169 ND2 ASN A 344 53.095 -18.460 -4.865 1.00 10.43 N ANISOU 169 ND2 ASN A 344 1367 1239 1355 148 -105 90 N ATOM 170 N GLY A 345 53.696 -17.240 -10.097 1.00 9.26 N ANISOU 170 N GLY A 345 1142 1154 1220 -14 -7 37 N ATOM 171 CA GLY A 345 53.436 -16.450 -11.301 1.00 9.29 C ANISOU 171 CA GLY A 345 1116 1179 1235 24 -18 33 C ATOM 172 C GLY A 345 52.619 -15.201 -11.054 1.00 9.06 C ANISOU 172 C GLY A 345 968 1241 1231 20 34 19 C ATOM 173 O GLY A 345 51.945 -14.704 -11.967 1.00 9.55 O ANISOU 173 O GLY A 345 1052 1393 1183 221 44 -64 O ATOM 174 N ILE A 346 52.690 -14.685 -9.828 1.00 8.88 N ANISOU 174 N ILE A 346 873 1267 1232 42 -50 23 N ATOM 175 CA ILE A 346 51.961 -13.468 -9.422 1.00 9.35 C ANISOU 175 CA ILE A 346 1080 1213 1259 5 -36 -45 C ATOM 176 C ILE A 346 52.957 -12.335 -9.343 1.00 10.01 C ANISOU 176 C ILE A 346 1134 1251 1418 -19 -141 5 C ATOM 177 O ILE A 346 54.079 -12.532 -8.865 1.00 10.98 O ANISOU 177 O ILE A 346 1130 1375 1667 160 -121 139 O ATOM 178 CB ILE A 346 51.296 -13.689 -8.055 1.00 9.45 C ANISOU 178 CB ILE A 346 1125 1212 1252 12 -21 -19 C ATOM 179 CG1 ILE A 346 50.160 -14.702 -8.209 1.00 9.25 C ANISOU 179 CG1 ILE A 346 1131 1157 1225 30 -13 -11 C ATOM 180 CG2 ILE A 346 50.787 -12.383 -7.436 1.00 9.87 C ANISOU 180 CG2 ILE A 346 1342 1162 1245 -28 -4 4 C ATOM 181 CD1 ILE A 346 49.722 -15.318 -6.900 1.00 9.65 C ANISOU 181 CD1 ILE A 346 1217 1180 1270 7 51 -4 C ATOM 182 N SER A 347 52.544 -11.167 -9.826 1.00 10.54 N ANISOU 182 N SER A 347 1170 1304 1528 134 -152 -34 N ATOM 183 CA SER A 347 53.286 -9.921 -9.679 1.00 11.24 C ANISOU 183 CA SER A 347 1354 1331 1582 52 -77 -17 C ATOM 184 C SER A 347 52.858 -9.238 -8.367 1.00 11.49 C ANISOU 184 C SER A 347 1325 1341 1697 88 -40 -87 C ATOM 185 O SER A 347 51.669 -9.133 -8.071 1.00 11.43 O ANISOU 185 O SER A 347 1225 1400 1716 -50 -123 -240 O ATOM 186 CB SER A 347 53.025 -8.997 -10.876 1.00 11.44 C ANISOU 186 CB SER A 347 1437 1294 1613 46 -126 -41 C ATOM 187 OG SER A 347 53.365 -7.650 -10.584 1.00 12.31 O ANISOU 187 OG SER A 347 1422 1295 1959 -101 -268 63 O ATOM 188 N HIS A 348 53.828 -8.775 -7.591 1.00 11.89 N ANISOU 188 N HIS A 348 1370 1303 1844 -32 -101 12 N ATOM 189 CA HIS A 348 53.544 -8.100 -6.317 1.00 13.72 C ANISOU 189 CA HIS A 348 1677 1694 1841 -48 74 -6 C ATOM 190 C HIS A 348 52.917 -6.710 -6.480 1.00 12.81 C ANISOU 190 C HIS A 348 1542 1617 1708 -143 -33 -87 C ATOM 191 O HIS A 348 52.391 -6.170 -5.510 1.00 13.04 O ANISOU 191 O HIS A 348 1687 1727 1540 -137 67 96 O ATOM 192 CB HIS A 348 54.802 -8.035 -5.431 1.00 17.02 C ANISOU 192 CB HIS A 348 2012 2253 2201 -41 -206 -55 C ATOM 193 CG HIS A 348 55.874 -7.115 -5.938 1.00 21.26 C ANISOU 193 CG HIS A 348 2381 2865 2831 -296 48 182 C ATOM 194 ND1 HIS A 348 56.880 -7.536 -6.781 1.00 26.06 N ANISOU 194 ND1 HIS A 348 3215 3354 3332 -4 447 -92 N ATOM 195 CD2 HIS A 348 56.111 -5.801 -5.699 1.00 24.07 C ANISOU 195 CD2 HIS A 348 2983 2955 3204 -124 51 -182 C ATOM 196 CE1 HIS A 348 57.685 -6.521 -7.049 1.00 27.55 C ANISOU 196 CE1 HIS A 348 3112 3527 3827 -341 26 -226 C ATOM 197 NE2 HIS A 348 57.237 -5.455 -6.407 1.00 26.38 N ANISOU 197 NE2 HIS A 348 2773 3537 3713 -432 -78 -226 N ATOM 198 N ARG A 349 52.955 -6.148 -7.692 1.00 11.81 N ANISOU 198 N ARG A 349 1295 1551 1639 -167 -86 -147 N ATOM 199 CA ARG A 349 52.437 -4.798 -7.981 1.00 13.10 C ANISOU 199 CA ARG A 349 1487 1683 1808 -26 -231 -112 C ATOM 200 C ARG A 349 51.050 -4.757 -8.650 1.00 10.75 C ANISOU 200 C ARG A 349 1328 1180 1574 4 -41 -69 C ATOM 201 O ARG A 349 50.348 -3.749 -8.527 1.00 9.90 O ANISOU 201 O ARG A 349 1338 959 1462 -114 30 24 O ATOM 202 CB ARG A 349 53.433 -4.063 -8.880 1.00 16.94 C ANISOU 202 CB ARG A 349 2006 2299 2130 -248 78 -12 C ATOM 203 CG ARG A 349 53.232 -2.554 -9.004 1.00 22.51 C ANISOU 203 CG ARG A 349 2948 2507 3095 -60 71 -8 C ATOM 204 CD ARG A 349 53.629 -1.795 -7.733 1.00 28.07 C ANISOU 204 CD ARG A 349 3751 3449 3462 -469 -32 -439 C ATOM 205 NE ARG A 349 53.518 -0.347 -7.932 1.00 33.33 N ANISOU 205 NE ARG A 349 4411 3687 4563 -148 246 101 N ATOM 206 CZ ARG A 349 54.437 0.439 -8.504 1.00 36.10 C ANISOU 206 CZ ARG A 349 4225 4594 4894 -434 859 -270 C ATOM 207 NH1 ARG A 349 55.605 -0.042 -8.950 1.00 24.79 N ANISOU 207 NH1 ARG A 349 3067 3349 3001 -1794 1234 1288 N ATOM 208 NH2 ARG A 349 54.189 1.741 -8.627 1.00 40.67 N ANISOU 208 NH2 ARG A 349 4783 4858 5811 131 746 -237 N ATOM 209 N SER A 350 50.674 -5.820 -9.365 1.00 9.12 N ANISOU 209 N SER A 350 1082 1108 1274 94 -101 39 N ATOM 210 CA SER A 350 49.395 -5.874 -10.102 1.00 8.90 C ANISOU 210 CA SER A 350 1114 1029 1236 -67 -94 -25 C ATOM 211 C SER A 350 48.791 -7.261 -9.938 1.00 8.23 C ANISOU 211 C SER A 350 1006 1009 1109 -11 -82 -44 C ATOM 212 O SER A 350 49.378 -8.239 -10.385 1.00 7.90 O ANISOU 212 O SER A 350 995 949 1055 -39 -129 -32 O ATOM 213 CB SER A 350 49.623 -5.576 -11.588 1.00 9.26 C ANISOU 213 CB SER A 350 1191 1092 1233 -113 -119 -14 C ATOM 214 OG SER A 350 50.548 -4.506 -11.787 1.00 10.10 O ANISOU 214 OG SER A 350 1255 1030 1551 -106 -215 108 O ATOM 215 N ARG A 351 47.639 -7.346 -9.279 1.00 7.85 N ANISOU 215 N ARG A 351 955 888 1137 5 -102 -84 N ATOM 216 CA ARG A 351 47.069 -8.625 -8.884 1.00 7.68 C ANISOU 216 CA ARG A 351 863 992 1062 -22 -73 -35 C ATOM 217 C ARG A 351 45.624 -8.750 -9.316 1.00 7.27 C ANISOU 217 C ARG A 351 875 895 989 -13 -100 -37 C ATOM 218 O ARG A 351 44.874 -7.767 -9.297 1.00 6.79 O ANISOU 218 O ARG A 351 756 854 968 -84 -207 -15 O ATOM 219 CB ARG A 351 47.264 -8.837 -7.392 1.00 7.93 C ANISOU 219 CB ARG A 351 947 1003 1059 -16 -41 -18 C ATOM 220 CG ARG A 351 48.758 -8.993 -7.103 1.00 8.55 C ANISOU 220 CG ARG A 351 971 1112 1164 6 -66 39 C ATOM 221 CD ARG A 351 49.080 -9.070 -5.639 1.00 8.93 C ANISOU 221 CD ARG A 351 1080 1173 1139 -58 -25 19 C ATOM 222 NE ARG A 351 48.524 -10.283 -5.041 1.00 8.57 N ANISOU 222 NE ARG A 351 1006 1056 1192 50 -23 12 N ATOM 223 CZ ARG A 351 48.641 -10.595 -3.763 1.00 9.07 C ANISOU 223 CZ ARG A 351 1143 1079 1221 89 -82 49 C ATOM 224 NH1 ARG A 351 49.349 -9.817 -2.945 1.00 9.56 N ANISOU 224 NH1 ARG A 351 1198 1193 1241 70 -113 13 N ATOM 225 NH2 ARG A 351 48.056 -11.697 -3.299 1.00 9.89 N ANISOU 225 NH2 ARG A 351 1295 1128 1333 26 -58 80 N ATOM 226 N TYR A 352 45.246 -9.973 -9.684 1.00 6.78 N ANISOU 226 N TYR A 352 803 861 913 4 -104 6 N ATOM 227 CA TYR A 352 44.003 -10.219 -10.425 1.00 6.43 C ANISOU 227 CA TYR A 352 774 815 852 -22 -56 38 C ATOM 228 C TYR A 352 43.196 -11.332 -9.811 1.00 6.02 C ANISOU 228 C TYR A 352 760 794 730 -10 -75 29 C ATOM 229 O TYR A 352 43.717 -12.407 -9.574 1.00 5.27 O ANISOU 229 O TYR A 352 593 749 657 -106 -62 62 O ATOM 230 CB TYR A 352 44.318 -10.567 -11.881 1.00 6.78 C ANISOU 230 CB TYR A 352 840 862 872 -13 -39 7 C ATOM 231 CG TYR A 352 45.113 -9.492 -12.570 1.00 7.09 C ANISOU 231 CG TYR A 352 898 857 936 -6 -31 53 C ATOM 232 CD1 TYR A 352 46.510 -9.452 -12.462 1.00 6.99 C ANISOU 232 CD1 TYR A 352 880 825 947 35 -4 22 C ATOM 233 CD2 TYR A 352 44.476 -8.471 -13.290 1.00 7.21 C ANISOU 233 CD2 TYR A 352 896 882 959 38 -37 31 C ATOM 234 CE1 TYR A 352 47.254 -8.449 -13.076 1.00 7.18 C ANISOU 234 CE1 TYR A 352 865 890 972 8 15 14 C ATOM 235 CE2 TYR A 352 45.221 -7.472 -13.908 1.00 7.21 C ANISOU 235 CE2 TYR A 352 856 904 979 31 -7 16 C ATOM 236 CZ TYR A 352 46.615 -7.470 -13.799 1.00 7.13 C ANISOU 236 CZ TYR A 352 853 933 921 15 -5 5 C ATOM 237 OH TYR A 352 47.356 -6.463 -14.395 1.00 6.85 O ANISOU 237 OH TYR A 352 642 1080 881 8 28 -26 O ATOM 238 N PHE A 353 41.914 -11.069 -9.585 1.00 6.04 N ANISOU 238 N PHE A 353 767 790 737 0 -77 68 N ATOM 239 CA PHE A 353 40.997 -12.040 -8.993 1.00 6.39 C ANISOU 239 CA PHE A 353 784 819 824 -22 -30 42 C ATOM 240 C PHE A 353 39.797 -12.218 -9.908 1.00 6.89 C ANISOU 240 C PHE A 353 849 903 866 -6 -84 26 C ATOM 241 O PHE A 353 39.312 -11.238 -10.497 1.00 7.25 O ANISOU 241 O PHE A 353 867 922 965 -40 -135 75 O ATOM 242 CB PHE A 353 40.527 -11.538 -7.633 1.00 6.41 C ANISOU 242 CB PHE A 353 792 800 842 -7 -36 22 C ATOM 243 CG PHE A 353 41.609 -11.483 -6.606 1.00 6.22 C ANISOU 243 CG PHE A 353 823 768 769 -11 -20 2 C ATOM 244 CD1 PHE A 353 42.462 -10.383 -6.535 1.00 6.11 C ANISOU 244 CD1 PHE A 353 770 771 779 7 -10 -4 C ATOM 245 CD2 PHE A 353 41.812 -12.553 -5.734 1.00 6.00 C ANISOU 245 CD2 PHE A 353 790 709 780 17 -17 -35 C ATOM 246 CE1 PHE A 353 43.467 -10.341 -5.595 1.00 6.11 C ANISOU 246 CE1 PHE A 353 763 773 784 5 -5 -20 C ATOM 247 CE2 PHE A 353 42.813 -12.513 -4.791 1.00 6.00 C ANISOU 247 CE2 PHE A 353 772 711 797 59 -21 -23 C ATOM 248 CZ PHE A 353 43.650 -11.409 -4.727 1.00 6.27 C ANISOU 248 CZ PHE A 353 772 780 831 17 -15 0 C ATOM 249 N ILE A 354 39.322 -13.455 -10.026 1.00 7.41 N ANISOU 249 N ILE A 354 943 908 961 -42 -45 87 N ATOM 250 CA ILE A 354 38.148 -13.765 -10.847 1.00 8.12 C ANISOU 250 CA ILE A 354 1036 1035 1013 -60 -92 17 C ATOM 251 C ILE A 354 36.899 -13.715 -9.975 1.00 8.56 C ANISOU 251 C ILE A 354 1085 1073 1094 -59 -36 6 C ATOM 252 O ILE A 354 36.878 -14.299 -8.899 1.00 8.94 O ANISOU 252 O ILE A 354 1090 1202 1102 -48 -45 47 O ATOM 253 CB ILE A 354 38.265 -15.127 -11.599 1.00 8.47 C ANISOU 253 CB ILE A 354 1108 1055 1052 -44 -28 1 C ATOM 254 CG1 ILE A 354 37.085 -15.293 -12.575 1.00 8.79 C ANISOU 254 CG1 ILE A 354 1094 1128 1118 -69 -36 -4 C ATOM 255 CG2 ILE A 354 38.367 -16.333 -10.667 1.00 8.27 C ANISOU 255 CG2 ILE A 354 1060 1055 1026 -60 -31 -9 C ATOM 256 CD1 ILE A 354 37.239 -16.476 -13.489 1.00 9.20 C ANISOU 256 CD1 ILE A 354 1161 1232 1102 19 -27 -44 C ATOM 257 N MET A 355 35.870 -13.007 -10.440 1.00 8.78 N ANISOU 257 N MET A 355 1166 1014 1155 -63 -93 14 N ATOM 258 CA MET A 355 34.571 -12.965 -9.773 1.00 9.16 C ANISOU 258 CA MET A 355 1181 1119 1178 -119 -71 -17 C ATOM 259 C MET A 355 33.617 -13.706 -10.701 1.00 9.45 C ANISOU 259 C MET A 355 1238 1142 1209 -137 -121 -14 C ATOM 260 O MET A 355 33.315 -13.218 -11.792 1.00 7.90 O ANISOU 260 O MET A 355 1078 741 1180 -388 -134 -76 O ATOM 261 CB MET A 355 34.108 -11.522 -9.572 1.00 10.20 C ANISOU 261 CB MET A 355 1327 1219 1327 16 9 -34 C ATOM 262 CG MET A 355 35.040 -10.705 -8.706 1.00 11.46 C ANISOU 262 CG MET A 355 1497 1317 1537 -11 -63 -137 C ATOM 263 SD MET A 355 34.943 -11.156 -6.965 1.00 14.23 S ANISOU 263 SD MET A 355 1873 1843 1689 37 -32 102 S ATOM 264 CE MET A 355 36.689 -11.358 -6.617 1.00 12.88 C ANISOU 264 CE MET A 355 1797 1378 1719 146 77 20 C ATOM 265 N LEU A 356 33.194 -14.899 -10.293 1.00 9.46 N ANISOU 265 N LEU A 356 1223 1147 1221 -87 -7 -5 N ATOM 266 CA LEU A 356 32.273 -15.707 -11.097 1.00 10.90 C ANISOU 266 CA LEU A 356 1461 1336 1341 -152 -80 -115 C ATOM 267 C LEU A 356 30.866 -15.311 -10.736 1.00 11.74 C ANISOU 267 C LEU A 356 1495 1456 1508 -136 -17 -68 C ATOM 268 O LEU A 356 30.457 -15.505 -9.597 1.00 13.34 O ANISOU 268 O LEU A 356 1646 1701 1718 -119 200 180 O ATOM 269 CB LEU A 356 32.494 -17.202 -10.859 1.00 11.78 C ANISOU 269 CB LEU A 356 1590 1394 1489 -108 -63 6 C ATOM 270 CG LEU A 356 33.856 -17.718 -11.352 1.00 12.54 C ANISOU 270 CG LEU A 356 1656 1496 1612 -54 -19 -52 C ATOM 271 CD1 LEU A 356 34.116 -19.106 -10.815 1.00 13.11 C ANISOU 271 CD1 LEU A 356 1779 1559 1644 143 -92 -62 C ATOM 272 CD2 LEU A 356 33.932 -17.729 -12.869 1.00 12.95 C ANISOU 272 CD2 LEU A 356 1711 1579 1629 -75 54 -64 C ATOM 273 N CYS A 357 30.143 -14.730 -11.690 1.00 12.80 N ANISOU 273 N CYS A 357 1833 1565 1463 -31 -61 -44 N ATOM 274 CA CYS A 357 28.822 -14.142 -11.443 1.00 14.10 C ANISOU 274 CA CYS A 357 1828 1804 1723 -30 54 -64 C ATOM 275 C CYS A 357 27.706 -15.055 -11.897 1.00 14.50 C ANISOU 275 C CYS A 357 1919 1822 1768 -92 40 -46 C ATOM 276 O CYS A 357 27.677 -15.467 -13.050 1.00 12.56 O ANISOU 276 O CYS A 357 1260 1894 1618 -310 21 99 O ATOM 277 CB CYS A 357 28.685 -12.818 -12.191 1.00 14.54 C ANISOU 277 CB CYS A 357 1974 1719 1830 52 2 -129 C ATOM 278 SG CYS A 357 30.024 -11.675 -11.845 1.00 16.78 S ANISOU 278 SG CYS A 357 2122 1853 2399 26 -144 -427 S ATOM 279 N ASP A 358 26.787 -15.357 -10.987 1.00 16.64 N ANISOU 279 N ASP A 358 1939 2216 2168 67 315 -56 N ATOM 280 CA ASP A 358 25.647 -16.216 -11.287 1.00 19.41 C ANISOU 280 CA ASP A 358 2101 2515 2758 -49 150 -93 C ATOM 281 C ASP A 358 24.314 -15.492 -11.056 1.00 21.80 C ANISOU 281 C ASP A 358 2298 2676 3307 208 198 -25 C ATOM 282 O ASP A 358 23.268 -16.130 -11.085 1.00 25.00 O ANISOU 282 O ASP A 358 2304 2727 4467 182 261 -374 O ATOM 283 CB ASP A 358 25.719 -17.505 -10.447 1.00 22.65 C ANISOU 283 CB ASP A 358 2815 2450 3340 33 185 25 C ATOM 284 CG ASP A 358 25.619 -17.260 -8.930 1.00 25.83 C ANISOU 284 CG ASP A 358 3309 3063 3442 30 355 -10 C ATOM 285 OD1 ASP A 358 25.585 -16.094 -8.466 1.00 27.00 O ANISOU 285 OD1 ASP A 358 3858 2676 3725 625 555 484 O ATOM 286 OD2 ASP A 358 25.586 -18.263 -8.183 1.00 31.00 O ANISOU 286 OD2 ASP A 358 4111 3622 4045 342 324 498 O ATOM 287 N ASN A 359 24.365 -14.174 -10.856 1.00 21.50 N ANISOU 287 N ASN A 359 2448 2702 3019 -33 184 -13 N ATOM 288 CA ASN A 359 23.211 -13.365 -10.439 1.00 22.07 C ANISOU 288 CA ASN A 359 2675 2744 2965 157 219 225 C ATOM 289 C ASN A 359 23.131 -12.126 -11.327 1.00 22.37 C ANISOU 289 C ASN A 359 2566 2690 3243 -9 -127 250 C ATOM 290 O ASN A 359 23.990 -11.241 -11.233 1.00 21.47 O ANISOU 290 O ASN A 359 1762 2848 3547 154 327 597 O ATOM 291 CB ASN A 359 23.403 -12.968 -8.971 1.00 20.89 C ANISOU 291 CB ASN A 359 2378 2816 2743 330 419 397 C ATOM 292 CG ASN A 359 22.137 -12.440 -8.314 1.00 18.19 C ANISOU 292 CG ASN A 359 2661 2589 1660 495 533 1111 C ATOM 293 OD1 ASN A 359 21.419 -11.598 -8.865 1.00 20.82 O ANISOU 293 OD1 ASN A 359 2501 2739 2668 791 16 725 O ATOM 294 ND2 ASN A 359 21.881 -12.909 -7.095 1.00 13.02 N ANISOU 294 ND2 ASN A 359 1277 1766 1901 1161 899 1208 N ATOM 295 N GLU A 360 22.116 -12.075 -12.196 1.00 21.94 N ANISOU 295 N GLU A 360 2594 2702 3040 -124 -110 -2 N ATOM 296 CA GLU A 360 21.951 -10.958 -13.128 1.00 20.54 C ANISOU 296 CA GLU A 360 2431 2616 2756 92 -187 -257 C ATOM 297 C GLU A 360 21.743 -9.639 -12.399 1.00 19.54 C ANISOU 297 C GLU A 360 2336 2462 2624 -93 -437 -204 C ATOM 298 O GLU A 360 22.247 -8.616 -12.837 1.00 17.59 O ANISOU 298 O GLU A 360 1747 2390 2546 -220 -718 -467 O ATOM 299 CB GLU A 360 20.782 -11.193 -14.094 1.00 22.32 C ANISOU 299 CB GLU A 360 2790 2838 2853 -85 -432 -300 C ATOM 300 N THR A 361 20.997 -9.681 -11.296 1.00 20.55 N ANISOU 300 N THR A 361 2537 2389 2882 -9 -191 -173 N ATOM 301 CA THR A 361 20.734 -8.491 -10.478 1.00 21.31 C ANISOU 301 CA THR A 361 2567 2618 2910 -172 -234 -349 C ATOM 302 C THR A 361 22.018 -7.911 -9.887 1.00 19.21 C ANISOU 302 C THR A 361 2466 2298 2534 -178 -120 -171 C ATOM 303 O THR A 361 22.218 -6.696 -9.939 1.00 18.94 O ANISOU 303 O THR A 361 2492 2383 2319 -637 -182 -612 O ATOM 304 CB THR A 361 19.736 -8.790 -9.339 1.00 23.53 C ANISOU 304 CB THR A 361 2773 2966 3201 54 32 -220 C ATOM 305 OG1 THR A 361 18.546 -9.375 -9.887 1.00 25.24 O ANISOU 305 OG1 THR A 361 2416 3316 3856 326 3 -428 O ATOM 306 CG2 THR A 361 19.365 -7.522 -8.595 1.00 25.08 C ANISOU 306 CG2 THR A 361 3202 3004 3321 119 101 -188 C ATOM 307 N ALA A 362 22.874 -8.777 -9.345 1.00 17.07 N ANISOU 307 N ALA A 362 1943 2172 2371 -244 182 -274 N ATOM 308 CA ALA A 362 24.122 -8.342 -8.690 1.00 16.64 C ANISOU 308 CA ALA A 362 2108 2057 2157 -66 -32 -195 C ATOM 309 C ALA A 362 25.061 -7.655 -9.673 1.00 16.80 C ANISOU 309 C ALA A 362 1994 2200 2189 -44 -15 -173 C ATOM 310 O ALA A 362 25.505 -6.529 -9.435 1.00 16.37 O ANISOU 310 O ALA A 362 1869 2244 2104 155 -309 -454 O ATOM 311 CB ALA A 362 24.822 -9.505 -8.013 1.00 15.83 C ANISOU 311 CB ALA A 362 1950 1997 2064 -213 -43 -97 C ATOM 312 N ILE A 363 25.337 -8.314 -10.796 1.00 17.59 N ANISOU 312 N ILE A 363 2235 2151 2296 25 216 -79 N ATOM 313 CA ILE A 363 26.215 -7.717 -11.809 1.00 16.83 C ANISOU 313 CA ILE A 363 2011 2205 2178 44 80 -33 C ATOM 314 C ILE A 363 25.629 -6.421 -12.399 1.00 15.46 C ANISOU 314 C ILE A 363 1708 2249 1914 37 103 -14 C ATOM 315 O ILE A 363 26.360 -5.432 -12.564 1.00 13.41 O ANISOU 315 O ILE A 363 1257 1955 1884 360 43 -140 O ATOM 316 CB ILE A 363 26.647 -8.719 -12.910 1.00 17.68 C ANISOU 316 CB ILE A 363 2085 2331 2299 53 88 -123 C ATOM 317 CG1 ILE A 363 27.753 -8.095 -13.781 1.00 18.17 C ANISOU 317 CG1 ILE A 363 2197 2276 2428 2 60 32 C ATOM 318 CG2 ILE A 363 25.472 -9.177 -13.775 1.00 17.62 C ANISOU 318 CG2 ILE A 363 2170 2164 2357 46 30 -118 C ATOM 319 CD1 ILE A 363 29.006 -7.712 -13.013 1.00 18.52 C ANISOU 319 CD1 ILE A 363 2335 2281 2418 -52 -48 57 C ATOM 320 N ALA A 364 24.323 -6.415 -12.679 1.00 14.55 N ANISOU 320 N ALA A 364 1716 2025 1785 -39 67 122 N ATOM 321 CA ALA A 364 23.644 -5.211 -13.184 1.00 14.62 C ANISOU 321 CA ALA A 364 1531 2062 1962 89 0 -48 C ATOM 322 C ALA A 364 23.778 -4.031 -12.214 1.00 14.22 C ANISOU 322 C ALA A 364 1333 2105 1965 152 -222 -43 C ATOM 323 O ALA A 364 24.131 -2.922 -12.620 1.00 12.38 O ANISOU 323 O ALA A 364 1141 1975 1588 543 -465 62 O ATOM 324 CB ALA A 364 22.169 -5.497 -13.472 1.00 14.22 C ANISOU 324 CB ALA A 364 1632 1855 1914 -63 -52 -65 C ATOM 325 N HIS A 365 23.523 -4.288 -10.932 1.00 14.17 N ANISOU 325 N HIS A 365 1309 1999 2073 186 -91 10 N ATOM 326 CA HIS A 365 23.623 -3.250 -9.905 1.00 15.58 C ANISOU 326 CA HIS A 365 1627 2071 2219 197 -102 -100 C ATOM 327 C HIS A 365 25.065 -2.753 -9.715 1.00 13.97 C ANISOU 327 C HIS A 365 1609 1708 1990 190 75 -80 C ATOM 328 O HIS A 365 25.295 -1.549 -9.564 1.00 13.86 O ANISOU 328 O HIS A 365 1475 1537 2251 515 316 40 O ATOM 329 CB HIS A 365 23.029 -3.738 -8.583 1.00 18.64 C ANISOU 329 CB HIS A 365 2174 2421 2486 101 127 108 C ATOM 330 CG HIS A 365 22.674 -2.631 -7.639 1.00 23.50 C ANISOU 330 CG HIS A 365 2914 2884 3130 83 293 -382 C ATOM 331 ND1 HIS A 365 21.722 -1.676 -7.937 1.00 27.10 N ANISOU 331 ND1 HIS A 365 3495 3467 3333 388 108 31 N ATOM 332 CD2 HIS A 365 23.130 -2.332 -6.399 1.00 26.88 C ANISOU 332 CD2 HIS A 365 3345 3707 3160 353 -17 -111 C ATOM 333 CE1 HIS A 365 21.617 -0.829 -6.927 1.00 27.95 C ANISOU 333 CE1 HIS A 365 3287 3603 3729 346 415 -238 C ATOM 334 NE2 HIS A 365 22.459 -1.205 -5.979 1.00 28.31 N ANISOU 334 NE2 HIS A 365 3429 3682 3643 220 356 -238 N ATOM 335 N ALA A 366 26.025 -3.677 -9.736 1.00 11.93 N ANISOU 335 N ALA A 366 1468 1476 1589 33 106 -225 N ATOM 336 CA ALA A 366 27.460 -3.337 -9.630 1.00 11.76 C ANISOU 336 CA ALA A 366 1515 1429 1524 -52 83 -112 C ATOM 337 C ALA A 366 27.942 -2.481 -10.794 1.00 12.03 C ANISOU 337 C ALA A 366 1500 1493 1577 -64 70 -59 C ATOM 338 O ALA A 366 28.817 -1.630 -10.622 1.00 12.50 O ANISOU 338 O ALA A 366 1775 1527 1444 -193 -110 -8 O ATOM 339 CB ALA A 366 28.297 -4.595 -9.536 1.00 11.51 C ANISOU 339 CB ALA A 366 1414 1515 1442 -53 -10 -50 C ATOM 340 N LYS A 367 27.392 -2.713 -11.981 1.00 12.13 N ANISOU 340 N LYS A 367 1475 1508 1624 -56 65 -97 N ATOM 341 CA LYS A 367 27.712 -1.873 -13.133 1.00 13.17 C ANISOU 341 CA LYS A 367 1739 1643 1620 47 45 -47 C ATOM 342 C LYS A 367 27.152 -0.448 -12.995 1.00 14.54 C ANISOU 342 C LYS A 367 2090 1574 1859 28 -37 -87 C ATOM 343 O LYS A 367 27.804 0.499 -13.420 1.00 15.94 O ANISOU 343 O LYS A 367 2328 1505 2220 103 74 96 O ATOM 344 CB LYS A 367 27.280 -2.548 -14.437 1.00 12.86 C ANISOU 344 CB LYS A 367 1648 1610 1627 -6 100 -63 C ATOM 345 CG LYS A 367 28.178 -3.728 -14.794 1.00 11.78 C ANISOU 345 CG LYS A 367 1470 1556 1450 -62 140 -30 C ATOM 346 CD LYS A 367 27.828 -4.360 -16.146 1.00 11.52 C ANISOU 346 CD LYS A 367 1416 1476 1483 -8 49 -6 C ATOM 347 CE LYS A 367 28.909 -5.352 -16.580 1.00 11.21 C ANISOU 347 CE LYS A 367 1450 1426 1381 -45 86 -39 C ATOM 348 NZ LYS A 367 28.588 -6.061 -17.863 1.00 11.56 N ANISOU 348 NZ LYS A 367 1518 1495 1377 9 55 -42 N ATOM 349 N LYS A 368 25.979 -0.306 -12.377 1.00 15.96 N ANISOU 349 N LYS A 368 2035 1937 2092 29 -105 -287 N ATOM 350 CA LYS A 368 25.400 1.027 -12.086 1.00 17.73 C ANISOU 350 CA LYS A 368 2446 2004 2286 180 -45 -193 C ATOM 351 C LYS A 368 26.062 1.728 -10.892 1.00 16.19 C ANISOU 351 C LYS A 368 2211 1804 2134 132 37 -24 C ATOM 352 O LYS A 368 26.360 2.925 -10.967 1.00 18.50 O ANISOU 352 O LYS A 368 2683 1825 2519 17 -138 228 O ATOM 353 CB LYS A 368 23.899 0.928 -11.805 1.00 21.47 C ANISOU 353 CB LYS A 368 2529 2671 2954 86 31 -18 C ATOM 354 CG LYS A 368 23.064 0.489 -12.988 1.00 26.78 C ANISOU 354 CG LYS A 368 3322 3533 3319 12 -307 -202 C ATOM 355 CD LYS A 368 21.572 0.605 -12.680 1.00 31.59 C ANISOU 355 CD LYS A 368 3473 4358 4170 181 13 -28 C ATOM 356 CE LYS A 368 20.759 -0.383 -13.499 1.00 35.78 C ANISOU 356 CE LYS A 368 4429 4662 4503 68 -208 -359 C ATOM 357 NZ LYS A 368 20.963 -0.205 -14.966 1.00 38.95 N ANISOU 357 NZ LYS A 368 5034 4995 4770 -52 146 154 N ATOM 358 N THR A 369 26.251 0.998 -9.790 1.00 14.65 N ANISOU 358 N THR A 369 1904 1693 1968 203 -85 -171 N ATOM 359 CA THR A 369 26.682 1.590 -8.505 1.00 13.74 C ANISOU 359 CA THR A 369 1709 1672 1837 109 22 -80 C ATOM 360 C THR A 369 28.172 1.467 -8.151 1.00 12.18 C ANISOU 360 C THR A 369 1661 1435 1532 109 106 -46 C ATOM 361 O THR A 369 28.621 2.103 -7.212 1.00 10.74 O ANISOU 361 O THR A 369 1263 1254 1563 283 210 -105 O ATOM 362 CB THR A 369 25.893 0.993 -7.323 1.00 14.60 C ANISOU 362 CB THR A 369 1858 1806 1883 -104 17 -67 C ATOM 363 OG1 THR A 369 26.184 -0.405 -7.206 1.00 13.98 O ANISOU 363 OG1 THR A 369 1674 1766 1870 -426 -191 242 O ATOM 364 CG2 THR A 369 24.397 1.219 -7.509 1.00 15.56 C ANISOU 364 CG2 THR A 369 1922 1935 2054 -99 -57 -46 C ATOM 365 N SER A 370 28.922 0.633 -8.869 1.00 12.51 N ANISOU 365 N SER A 370 1595 1523 1631 224 44 -46 N ATOM 366 CA SER A 370 30.360 0.421 -8.609 1.00 12.54 C ANISOU 366 CA SER A 370 1582 1575 1605 177 44 -31 C ATOM 367 C SER A 370 30.683 -0.046 -7.175 1.00 13.23 C ANISOU 367 C SER A 370 1760 1572 1695 180 -32 16 C ATOM 368 O SER A 370 31.756 0.262 -6.648 1.00 12.88 O ANISOU 368 O SER A 370 1661 1508 1723 147 53 136 O ATOM 369 CB SER A 370 31.172 1.666 -8.979 1.00 12.06 C ANISOU 369 CB SER A 370 1494 1526 1559 245 27 -55 C ATOM 370 OG SER A 370 31.026 1.983 -10.357 1.00 11.92 O ANISOU 370 OG SER A 370 1408 1641 1479 263 129 -169 O ATOM 371 N ILE A 371 29.757 -0.795 -6.561 1.00 13.96 N ANISOU 371 N ILE A 371 1778 1663 1862 173 46 57 N ATOM 372 CA ILE A 371 30.027 -1.488 -5.292 1.00 16.10 C ANISOU 372 CA ILE A 371 2218 1903 1994 37 -67 176 C ATOM 373 C ILE A 371 29.916 -2.988 -5.561 1.00 15.20 C ANISOU 373 C ILE A 371 2065 1875 1833 18 -71 183 C ATOM 374 O ILE A 371 29.055 -3.423 -6.327 1.00 14.53 O ANISOU 374 O ILE A 371 2053 1622 1845 195 -187 248 O ATOM 375 CB ILE A 371 29.050 -1.084 -4.167 1.00 18.54 C ANISOU 375 CB ILE A 371 2507 2393 2144 110 77 34 C ATOM 376 CG1 ILE A 371 28.934 0.448 -4.036 1.00 20.42 C ANISOU 376 CG1 ILE A 371 2873 2429 2454 -118 -57 -23 C ATOM 377 CG2 ILE A 371 29.471 -1.705 -2.838 1.00 18.97 C ANISOU 377 CG2 ILE A 371 2508 2313 2384 239 -58 134 C ATOM 378 CD1 ILE A 371 30.231 1.178 -3.748 1.00 21.93 C ANISOU 378 CD1 ILE A 371 2844 2740 2747 -189 109 -38 C ATOM 379 N TRP A 372 30.806 -3.763 -4.946 1.00 14.13 N ANISOU 379 N TRP A 372 1934 1764 1668 -57 -49 54 N ATOM 380 CA TRP A 372 30.789 -5.217 -5.044 1.00 13.32 C ANISOU 380 CA TRP A 372 1763 1762 1535 40 -39 119 C ATOM 381 C TRP A 372 30.852 -5.827 -3.643 1.00 12.63 C ANISOU 381 C TRP A 372 1627 1678 1494 -73 -114 74 C ATOM 382 O TRP A 372 31.517 -5.282 -2.770 1.00 14.15 O ANISOU 382 O TRP A 372 2130 1870 1377 -127 -420 253 O ATOM 383 CB TRP A 372 31.990 -5.700 -5.871 1.00 13.43 C ANISOU 383 CB TRP A 372 1770 1731 1601 -4 -3 76 C ATOM 384 CG TRP A 372 31.887 -7.106 -6.235 1.00 12.99 C ANISOU 384 CG TRP A 372 1694 1660 1581 24 92 124 C ATOM 385 CD1 TRP A 372 32.660 -8.135 -5.780 1.00 13.70 C ANISOU 385 CD1 TRP A 372 1797 1704 1700 58 -56 76 C ATOM 386 CD2 TRP A 372 30.926 -7.679 -7.121 1.00 12.53 C ANISOU 386 CD2 TRP A 372 1627 1614 1518 33 134 129 C ATOM 387 NE1 TRP A 372 32.237 -9.323 -6.340 1.00 12.71 N ANISOU 387 NE1 TRP A 372 1650 1548 1629 40 73 201 N ATOM 388 CE2 TRP A 372 31.171 -9.069 -7.162 1.00 12.64 C ANISOU 388 CE2 TRP A 372 1662 1603 1536 -23 62 103 C ATOM 389 CE3 TRP A 372 29.877 -7.152 -7.884 1.00 12.52 C ANISOU 389 CE3 TRP A 372 1701 1532 1520 42 97 85 C ATOM 390 CZ2 TRP A 372 30.414 -9.937 -7.953 1.00 13.35 C ANISOU 390 CZ2 TRP A 372 1739 1637 1696 -144 29 133 C ATOM 391 CZ3 TRP A 372 29.114 -8.008 -8.657 1.00 12.84 C ANISOU 391 CZ3 TRP A 372 1700 1598 1581 10 75 88 C ATOM 392 CH2 TRP A 372 29.389 -9.393 -8.690 1.00 13.26 C ANISOU 392 CH2 TRP A 372 1773 1560 1702 -63 32 84 C ATOM 393 N ALA A 373 30.146 -6.934 -3.439 1.00 11.70 N ANISOU 393 N ALA A 373 1602 1392 1451 112 -178 20 N ATOM 394 CA ALA A 373 30.221 -7.694 -2.191 1.00 11.48 C ANISOU 394 CA ALA A 373 1536 1373 1452 78 -73 7 C ATOM 395 C ALA A 373 31.225 -8.821 -2.392 1.00 10.81 C ANISOU 395 C ALA A 373 1483 1261 1363 7 -80 5 C ATOM 396 O ALA A 373 31.169 -9.525 -3.388 1.00 10.16 O ANISOU 396 O ALA A 373 1297 1160 1401 73 -101 9 O ATOM 397 CB ALA A 373 28.860 -8.238 -1.793 1.00 12.08 C ANISOU 397 CB ALA A 373 1565 1493 1531 25 -50 -3 C ATOM 398 N VAL A 374 32.160 -8.951 -1.456 1.00 10.85 N ANISOU 398 N VAL A 374 1394 1318 1408 95 -43 -23 N ATOM 399 CA VAL A 374 33.270 -9.903 -1.544 1.00 10.11 C ANISOU 399 CA VAL A 374 1296 1272 1271 20 -8 -45 C ATOM 400 C VAL A 374 32.954 -11.114 -0.689 1.00 9.75 C ANISOU 400 C VAL A 374 1220 1236 1246 48 -60 -63 C ATOM 401 O VAL A 374 32.561 -10.967 0.466 1.00 8.89 O ANISOU 401 O VAL A 374 1388 889 1100 -58 -251 -143 O ATOM 402 CB VAL A 374 34.574 -9.232 -1.077 1.00 10.34 C ANISOU 402 CB VAL A 374 1272 1302 1353 5 5 0 C ATOM 403 CG1 VAL A 374 35.740 -10.209 -1.067 1.00 10.72 C ANISOU 403 CG1 VAL A 374 1367 1285 1420 49 -14 6 C ATOM 404 CG2 VAL A 374 34.890 -8.056 -1.998 1.00 10.61 C ANISOU 404 CG2 VAL A 374 1331 1340 1358 19 -3 44 C ATOM 405 N LYS A 375 33.124 -12.303 -1.275 1.00 9.81 N ANISOU 405 N LYS A 375 1233 1278 1215 16 -52 -93 N ATOM 406 CA LYS A 375 32.854 -13.575 -0.613 1.00 10.24 C ANISOU 406 CA LYS A 375 1283 1324 1282 -43 0 -56 C ATOM 407 C LYS A 375 33.787 -13.792 0.574 1.00 9.63 C ANISOU 407 C LYS A 375 1175 1214 1268 -60 45 -55 C ATOM 408 O LYS A 375 34.946 -13.386 0.546 1.00 9.07 O ANISOU 408 O LYS A 375 1078 1347 1021 29 177 -48 O ATOM 409 CB LYS A 375 33.031 -14.734 -1.595 1.00 10.92 C ANISOU 409 CB LYS A 375 1451 1301 1396 15 26 -55 C ATOM 410 CG LYS A 375 32.047 -14.756 -2.753 1.00 11.59 C ANISOU 410 CG LYS A 375 1547 1415 1440 6 -39 -38 C ATOM 411 CD LYS A 375 30.670 -15.187 -2.308 1.00 12.61 C ANISOU 411 CD LYS A 375 1619 1549 1620 -43 0 -12 C ATOM 412 CE LYS A 375 29.783 -15.372 -3.516 1.00 14.24 C ANISOU 412 CE LYS A 375 1851 1844 1715 -28 -115 -73 C ATOM 413 NZ LYS A 375 28.440 -15.849 -3.117 1.00 16.21 N ANISOU 413 NZ LYS A 375 2007 2190 1962 -222 -34 -3 N ATOM 414 N LYS A 376 33.282 -14.432 1.618 1.00 9.86 N ANISOU 414 N LYS A 376 1212 1186 1346 -64 107 -54 N ATOM 415 CA LYS A 376 34.082 -14.694 2.813 1.00 10.21 C ANISOU 415 CA LYS A 376 1282 1218 1380 -26 51 -66 C ATOM 416 C LYS A 376 35.370 -15.459 2.509 1.00 9.92 C ANISOU 416 C LYS A 376 1251 1173 1343 -58 -6 -21 C ATOM 417 O LYS A 376 36.409 -15.127 3.079 1.00 10.01 O ANISOU 417 O LYS A 376 1261 1100 1439 -100 -31 -6 O ATOM 418 CB LYS A 376 33.269 -15.434 3.875 1.00 11.26 C ANISOU 418 CB LYS A 376 1455 1300 1522 -19 83 63 C ATOM 419 CG LYS A 376 32.164 -14.590 4.498 1.00 12.42 C ANISOU 419 CG LYS A 376 1506 1565 1647 45 119 -50 C ATOM 420 CD LYS A 376 31.380 -15.369 5.538 1.00 14.36 C ANISOU 420 CD LYS A 376 1771 1815 1867 -49 106 163 C ATOM 421 CE LYS A 376 30.598 -14.421 6.425 1.00 16.70 C ANISOU 421 CE LYS A 376 2163 2075 2106 -5 228 -54 C ATOM 422 NZ LYS A 376 29.493 -15.119 7.135 1.00 19.09 N ANISOU 422 NZ LYS A 376 2260 2315 2676 -261 170 60 N ATOM 423 N ASP A 377 35.302 -16.441 1.598 1.00 9.68 N ANISOU 423 N ASP A 377 1289 1094 1294 -87 23 27 N ATOM 424 CA ASP A 377 36.450 -17.301 1.293 1.00 10.42 C ANISOU 424 CA ASP A 377 1369 1243 1345 5 37 34 C ATOM 425 C ASP A 377 37.655 -16.541 0.750 1.00 10.57 C ANISOU 425 C ASP A 377 1416 1204 1393 -41 43 -17 C ATOM 426 O ASP A 377 38.781 -16.828 1.137 1.00 11.92 O ANISOU 426 O ASP A 377 1618 1328 1584 128 -57 34 O ATOM 427 CB ASP A 377 36.088 -18.395 0.287 1.00 11.11 C ANISOU 427 CB ASP A 377 1461 1333 1426 -37 75 -41 C ATOM 428 CG ASP A 377 35.046 -19.376 0.797 1.00 12.58 C ANISOU 428 CG ASP A 377 1835 1341 1603 -162 163 43 C ATOM 429 OD1 ASP A 377 34.592 -19.275 1.953 1.00 12.68 O ANISOU 429 OD1 ASP A 377 1830 1274 1714 -267 302 17 O ATOM 430 OD2 ASP A 377 34.666 -20.267 0.004 1.00 14.93 O ANISOU 430 OD2 ASP A 377 2026 1676 1970 -450 71 -129 O ATOM 431 N SER A 378 37.403 -15.575 -0.131 1.00 10.54 N ANISOU 431 N SER A 378 1292 1433 1277 -71 -19 23 N ATOM 432 CA SER A 378 38.436 -14.802 -0.832 1.00 9.97 C ANISOU 432 CA SER A 378 1245 1230 1311 -43 -53 -3 C ATOM 433 C SER A 378 38.762 -13.440 -0.192 1.00 9.50 C ANISOU 433 C SER A 378 1144 1151 1314 -36 72 57 C ATOM 434 O SER A 378 39.751 -12.814 -0.567 1.00 8.11 O ANISOU 434 O SER A 378 847 862 1371 117 -69 -49 O ATOM 435 CB SER A 378 38.016 -14.597 -2.301 1.00 10.52 C ANISOU 435 CB SER A 378 1348 1327 1322 -19 -41 52 C ATOM 436 OG SER A 378 36.684 -14.093 -2.407 1.00 11.37 O ANISOU 436 OG SER A 378 1386 1523 1410 18 -117 72 O ATOM 437 N SER A 379 37.946 -12.998 0.771 1.00 9.40 N ANISOU 437 N SER A 379 1117 1135 1317 -24 34 9 N ATOM 438 CA SER A 379 38.053 -11.652 1.348 1.00 9.25 C ANISOU 438 CA SER A 379 1156 1142 1214 28 56 17 C ATOM 439 C SER A 379 39.427 -11.325 1.950 1.00 8.67 C ANISOU 439 C SER A 379 1067 1079 1145 64 138 25 C ATOM 440 O SER A 379 39.962 -10.235 1.693 1.00 7.83 O ANISOU 440 O SER A 379 996 869 1109 308 195 42 O ATOM 441 CB SER A 379 36.964 -11.444 2.400 1.00 9.41 C ANISOU 441 CB SER A 379 1166 1184 1224 -1 56 12 C ATOM 442 OG SER A 379 36.996 -12.477 3.362 1.00 9.30 O ANISOU 442 OG SER A 379 1135 1162 1235 -78 144 27 O ATOM 443 N LYS A 380 40.014 -12.245 2.729 1.00 7.99 N ANISOU 443 N LYS A 380 998 1008 1026 16 204 -1 N ATOM 444 CA LYS A 380 41.296 -11.934 3.393 1.00 8.31 C ANISOU 444 CA LYS A 380 1027 1051 1079 68 131 -8 C ATOM 445 C LYS A 380 42.418 -11.778 2.377 1.00 7.51 C ANISOU 445 C LYS A 380 1004 894 952 57 64 -4 C ATOM 446 O LYS A 380 43.227 -10.848 2.475 1.00 7.09 O ANISOU 446 O LYS A 380 1135 599 958 141 128 25 O ATOM 447 CB LYS A 380 41.695 -12.975 4.429 1.00 9.15 C ANISOU 447 CB LYS A 380 1221 1102 1150 51 28 12 C ATOM 448 CG LYS A 380 40.797 -13.033 5.645 1.00 10.27 C ANISOU 448 CG LYS A 380 1318 1296 1284 -1 122 13 C ATOM 449 CD LYS A 380 41.321 -14.016 6.684 1.00 11.39 C ANISOU 449 CD LYS A 380 1420 1496 1410 28 68 137 C ATOM 450 CE LYS A 380 41.075 -15.456 6.256 1.00 12.52 C ANISOU 450 CE LYS A 380 1615 1600 1540 -37 37 22 C ATOM 451 NZ LYS A 380 39.613 -15.768 6.165 1.00 13.80 N ANISOU 451 NZ LYS A 380 1690 1822 1729 -159 43 52 N ATOM 452 N ARG A 381 42.500 -12.697 1.421 1.00 7.22 N ANISOU 452 N ARG A 381 975 848 919 15 26 25 N ATOM 453 CA ARG A 381 43.557 -12.598 0.389 1.00 7.09 C ANISOU 453 CA ARG A 381 915 887 890 115 2 -17 C ATOM 454 C ARG A 381 43.428 -11.308 -0.436 1.00 6.83 C ANISOU 454 C ARG A 381 917 907 770 90 -4 -38 C ATOM 455 O ARG A 381 44.418 -10.636 -0.716 1.00 6.62 O ANISOU 455 O ARG A 381 920 768 824 124 -101 -21 O ATOM 456 CB ARG A 381 43.549 -13.812 -0.534 1.00 7.19 C ANISOU 456 CB ARG A 381 927 932 870 62 6 -27 C ATOM 457 CG ARG A 381 44.771 -13.827 -1.441 1.00 7.34 C ANISOU 457 CG ARG A 381 903 972 912 87 9 -32 C ATOM 458 CD ARG A 381 44.792 -15.045 -2.355 1.00 7.34 C ANISOU 458 CD ARG A 381 913 958 917 34 15 -24 C ATOM 459 NE ARG A 381 46.007 -15.078 -3.167 1.00 7.02 N ANISOU 459 NE ARG A 381 907 878 883 63 19 -12 N ATOM 460 CZ ARG A 381 47.172 -15.636 -2.811 1.00 7.07 C ANISOU 460 CZ ARG A 381 916 910 856 42 -8 25 C ATOM 461 NH1 ARG A 381 48.206 -15.594 -3.654 1.00 7.04 N ANISOU 461 NH1 ARG A 381 803 902 970 27 -28 24 N ATOM 462 NH2 ARG A 381 47.315 -16.259 -1.650 1.00 6.80 N ANISOU 462 NH2 ARG A 381 913 799 871 24 -9 20 N ATOM 463 N ILE A 382 42.203 -10.964 -0.819 1.00 6.60 N ANISOU 463 N ILE A 382 906 853 748 80 -5 -63 N ATOM 464 CA ILE A 382 41.954 -9.728 -1.577 1.00 6.84 C ANISOU 464 CA ILE A 382 895 882 821 34 -7 -5 C ATOM 465 C ILE A 382 42.372 -8.502 -0.745 1.00 6.94 C ANISOU 465 C ILE A 382 866 863 905 24 -54 8 C ATOM 466 O ILE A 382 43.121 -7.614 -1.218 1.00 6.47 O ANISOU 466 O ILE A 382 928 742 788 4 -164 -12 O ATOM 467 CB ILE A 382 40.460 -9.656 -2.018 1.00 7.23 C ANISOU 467 CB ILE A 382 899 961 886 19 -15 12 C ATOM 468 CG1 ILE A 382 40.162 -10.742 -3.078 1.00 7.31 C ANISOU 468 CG1 ILE A 382 929 951 897 6 -41 23 C ATOM 469 CG2 ILE A 382 40.108 -8.274 -2.556 1.00 7.37 C ANISOU 469 CG2 ILE A 382 926 955 917 54 1 -5 C ATOM 470 CD1 ILE A 382 38.675 -10.952 -3.343 1.00 7.55 C ANISOU 470 CD1 ILE A 382 953 971 945 -54 -47 15 C ATOM 471 N SER A 383 41.933 -8.475 0.510 1.00 7.23 N ANISOU 471 N SER A 383 933 892 923 21 -48 -8 N ATOM 472 CA SER A 383 42.267 -7.362 1.405 1.00 7.99 C ANISOU 472 CA SER A 383 1097 970 968 36 -48 -85 C ATOM 473 C SER A 383 43.784 -7.224 1.561 1.00 8.03 C ANISOU 473 C SER A 383 1102 1006 943 16 -23 -75 C ATOM 474 O SER A 383 44.323 -6.132 1.455 1.00 8.15 O ANISOU 474 O SER A 383 1278 905 913 71 7 -84 O ATOM 475 CB SER A 383 41.590 -7.532 2.756 1.00 8.14 C ANISOU 475 CB SER A 383 1078 990 1024 -16 -2 -128 C ATOM 476 OG SER A 383 41.793 -6.381 3.563 1.00 8.71 O ANISOU 476 OG SER A 383 1062 1085 1161 127 -18 -293 O ATOM 477 N ASP A 384 44.476 -8.347 1.755 1.00 8.53 N ANISOU 477 N ASP A 384 1167 1039 1032 46 -30 -16 N ATOM 478 CA ASP A 384 45.939 -8.330 1.885 1.00 9.07 C ANISOU 478 CA ASP A 384 1171 1169 1104 114 26 -61 C ATOM 479 C ASP A 384 46.611 -7.864 0.595 1.00 7.93 C ANISOU 479 C ASP A 384 1024 907 1080 53 -61 -65 C ATOM 480 O ASP A 384 47.561 -7.083 0.642 1.00 7.44 O ANISOU 480 O ASP A 384 1036 883 907 47 -160 -184 O ATOM 481 CB ASP A 384 46.448 -9.710 2.280 1.00 10.44 C ANISOU 481 CB ASP A 384 1387 1324 1253 280 -35 12 C ATOM 482 CG ASP A 384 47.953 -9.751 2.411 1.00 11.91 C ANISOU 482 CG ASP A 384 1407 1611 1506 376 -103 -110 C ATOM 483 OD1 ASP A 384 48.482 -9.269 3.433 1.00 13.08 O ANISOU 483 OD1 ASP A 384 1680 1825 1463 888 -413 -93 O ATOM 484 OD2 ASP A 384 48.608 -10.230 1.470 1.00 13.54 O ANISOU 484 OD2 ASP A 384 1592 1842 1708 433 102 -123 O ATOM 485 N ALA A 385 46.110 -8.328 -0.556 1.00 7.34 N ANISOU 485 N ALA A 385 1012 768 1010 82 0 -40 N ATOM 486 CA ALA A 385 46.645 -7.887 -1.858 1.00 7.63 C ANISOU 486 CA ALA A 385 985 903 1010 55 11 -35 C ATOM 487 C ALA A 385 46.519 -6.374 -2.066 1.00 7.65 C ANISOU 487 C ALA A 385 998 901 1005 37 52 -31 C ATOM 488 O ALA A 385 47.397 -5.726 -2.676 1.00 6.67 O ANISOU 488 O ALA A 385 822 763 949 128 44 -136 O ATOM 489 CB ALA A 385 45.940 -8.613 -2.986 1.00 7.99 C ANISOU 489 CB ALA A 385 1043 995 995 37 2 -37 C ATOM 490 N TYR A 386 45.429 -5.813 -1.545 1.00 7.60 N ANISOU 490 N TYR A 386 944 953 988 34 9 -11 N ATOM 491 CA TYR A 386 45.173 -4.379 -1.647 1.00 8.20 C ANISOU 491 CA TYR A 386 1081 980 1053 109 33 -52 C ATOM 492 C TYR A 386 46.206 -3.500 -0.918 1.00 8.89 C ANISOU 492 C TYR A 386 1048 1122 1205 15 71 -75 C ATOM 493 O TYR A 386 46.364 -2.348 -1.287 1.00 9.43 O ANISOU 493 O TYR A 386 1144 1210 1228 -55 41 -5 O ATOM 494 CB TYR A 386 43.750 -4.103 -1.148 1.00 8.25 C ANISOU 494 CB TYR A 386 1047 1012 1072 63 23 -19 C ATOM 495 CG TYR A 386 43.276 -2.676 -1.282 1.00 8.35 C ANISOU 495 CG TYR A 386 1051 1014 1105 70 -5 -20 C ATOM 496 CD1 TYR A 386 42.794 -2.189 -2.498 1.00 8.51 C ANISOU 496 CD1 TYR A 386 1142 1034 1058 61 8 -34 C ATOM 497 CD2 TYR A 386 43.280 -1.814 -0.183 1.00 8.32 C ANISOU 497 CD2 TYR A 386 1012 1067 1080 98 0 -25 C ATOM 498 CE1 TYR A 386 42.330 -0.880 -2.617 1.00 8.84 C ANISOU 498 CE1 TYR A 386 1209 1064 1084 94 13 0 C ATOM 499 CE2 TYR A 386 42.844 -0.494 -0.305 1.00 8.54 C ANISOU 499 CE2 TYR A 386 1092 1049 1103 90 24 -14 C ATOM 500 CZ TYR A 386 42.357 -0.043 -1.519 1.00 8.66 C ANISOU 500 CZ TYR A 386 1173 1025 1092 92 39 0 C ATOM 501 OH TYR A 386 41.912 1.249 -1.642 1.00 9.44 O ANISOU 501 OH TYR A 386 1329 1144 1113 293 46 -63 O ATOM 502 N LYS A 387 46.893 -4.038 0.100 1.00 9.73 N ANISOU 502 N LYS A 387 1226 1192 1277 76 43 -30 N ATOM 503 CA LYS A 387 47.913 -3.301 0.876 1.00 11.19 C ANISOU 503 CA LYS A 387 1325 1445 1481 4 -54 -59 C ATOM 504 C LYS A 387 49.041 -2.752 0.012 1.00 11.97 C ANISOU 504 C LYS A 387 1415 1662 1471 28 -29 67 C ATOM 505 O LYS A 387 49.476 -1.628 0.219 1.00 12.92 O ANISOU 505 O LYS A 387 1389 1942 1575 -240 -6 5 O ATOM 506 CB LYS A 387 48.591 -4.175 1.942 1.00 11.93 C ANISOU 506 CB LYS A 387 1491 1479 1563 102 -26 -3 C ATOM 507 CG LYS A 387 47.720 -4.774 3.028 1.00 13.70 C ANISOU 507 CG LYS A 387 1696 1721 1788 26 92 48 C ATOM 508 CD LYS A 387 48.567 -5.704 3.898 1.00 15.72 C ANISOU 508 CD LYS A 387 2065 1927 1981 85 -105 127 C ATOM 509 CE LYS A 387 47.734 -6.380 4.974 1.00 17.49 C ANISOU 509 CE LYS A 387 2258 2178 2207 36 86 124 C ATOM 510 NZ LYS A 387 48.372 -7.611 5.527 1.00 18.29 N ANISOU 510 NZ LYS A 387 2389 2267 2291 152 -66 85 N ATOM 511 N LYS A 388 49.548 -3.565 -0.914 1.00 12.25 N ANISOU 511 N LYS A 388 1486 1725 1443 -31 -187 -74 N ATOM 512 CA LYS A 388 50.741 -3.194 -1.685 1.00 14.00 C ANISOU 512 CA LYS A 388 1726 2004 1588 -138 -30 -59 C ATOM 513 C LYS A 388 50.656 -3.313 -3.213 1.00 12.54 C ANISOU 513 C LYS A 388 1373 1821 1569 -225 35 1 C ATOM 514 O LYS A 388 51.648 -3.018 -3.901 1.00 13.29 O ANISOU 514 O LYS A 388 1425 1808 1815 -296 167 40 O ATOM 515 CB LYS A 388 51.931 -4.018 -1.195 1.00 15.69 C ANISOU 515 CB LYS A 388 1942 2044 1974 64 -53 -22 C ATOM 516 CG LYS A 388 52.103 -4.018 0.312 1.00 17.36 C ANISOU 516 CG LYS A 388 2167 2422 2004 -91 -281 -95 C ATOM 517 N ALA A 389 49.505 -3.729 -3.734 1.00 10.05 N ANISOU 517 N ALA A 389 1289 1214 1315 -31 40 15 N ATOM 518 CA ALA A 389 49.328 -3.905 -5.166 1.00 10.10 C ANISOU 518 CA ALA A 389 1237 1257 1343 -20 -14 -37 C ATOM 519 C ALA A 389 48.140 -3.107 -5.671 1.00 9.51 C ANISOU 519 C ALA A 389 1296 1010 1307 -82 -76 -67 C ATOM 520 O ALA A 389 47.215 -2.788 -4.914 1.00 9.57 O ANISOU 520 O ALA A 389 1207 1033 1393 -48 -140 -69 O ATOM 521 CB ALA A 389 49.126 -5.385 -5.484 1.00 10.42 C ANISOU 521 CB ALA A 389 1357 1266 1336 -4 -87 -39 C ATOM 522 N SER A 390 48.176 -2.787 -6.956 1.00 8.81 N ANISOU 522 N SER A 390 1123 909 1314 -112 -22 -87 N ATOM 523 CA SER A 390 46.960 -2.506 -7.706 1.00 9.26 C ANISOU 523 CA SER A 390 1233 997 1285 -68 -53 -7 C ATOM 524 C SER A 390 46.184 -3.818 -7.860 1.00 8.59 C ANISOU 524 C SER A 390 1085 1001 1175 -39 -45 -14 C ATOM 525 O SER A 390 46.741 -4.820 -8.325 1.00 8.41 O ANISOU 525 O SER A 390 1112 700 1383 -156 -89 74 O ATOM 526 CB SER A 390 47.307 -1.930 -9.075 1.00 10.02 C ANISOU 526 CB SER A 390 1306 1176 1324 -187 -8 20 C ATOM 527 OG SER A 390 47.881 -0.635 -8.904 1.00 11.62 O ANISOU 527 OG SER A 390 1879 1196 1340 -327 10 -51 O ATOM 528 N VAL A 391 44.913 -3.815 -7.476 1.00 8.19 N ANISOU 528 N VAL A 391 1104 963 1044 1 -31 -2 N ATOM 529 CA VAL A 391 44.104 -5.037 -7.477 1.00 8.05 C ANISOU 529 CA VAL A 391 1017 990 1051 8 -50 7 C ATOM 530 C VAL A 391 42.941 -4.912 -8.449 1.00 7.59 C ANISOU 530 C VAL A 391 1012 912 959 16 -24 -25 C ATOM 531 O VAL A 391 42.197 -3.922 -8.410 1.00 6.94 O ANISOU 531 O VAL A 391 1062 820 752 -5 -79 -43 O ATOM 532 CB VAL A 391 43.579 -5.386 -6.062 1.00 8.48 C ANISOU 532 CB VAL A 391 1099 1057 1067 -21 -38 7 C ATOM 533 CG1 VAL A 391 42.780 -6.687 -6.091 1.00 8.61 C ANISOU 533 CG1 VAL A 391 1000 1104 1166 -36 42 68 C ATOM 534 CG2 VAL A 391 44.746 -5.522 -5.095 1.00 8.43 C ANISOU 534 CG2 VAL A 391 1103 987 1111 24 -53 76 C ATOM 535 N TYR A 392 42.762 -5.934 -9.290 1.00 7.18 N ANISOU 535 N TYR A 392 965 867 896 52 -29 15 N ATOM 536 CA TYR A 392 41.693 -5.938 -10.299 1.00 7.24 C ANISOU 536 CA TYR A 392 967 896 886 -16 -26 15 C ATOM 537 C TYR A 392 40.773 -7.128 -10.131 1.00 7.03 C ANISOU 537 C TYR A 392 965 847 860 22 -70 34 C ATOM 538 O TYR A 392 41.245 -8.249 -9.858 1.00 7.56 O ANISOU 538 O TYR A 392 1090 909 872 59 -233 103 O ATOM 539 CB TYR A 392 42.293 -5.952 -11.712 1.00 7.32 C ANISOU 539 CB TYR A 392 983 926 873 -53 -35 27 C ATOM 540 CG TYR A 392 43.252 -4.792 -11.920 1.00 7.18 C ANISOU 540 CG TYR A 392 941 942 842 -52 -28 38 C ATOM 541 CD1 TYR A 392 42.798 -3.546 -12.327 1.00 7.33 C ANISOU 541 CD1 TYR A 392 923 971 890 -21 -47 47 C ATOM 542 CD2 TYR A 392 44.605 -4.941 -11.662 1.00 7.26 C ANISOU 542 CD2 TYR A 392 963 969 825 -72 -83 69 C ATOM 543 CE1 TYR A 392 43.674 -2.471 -12.486 1.00 7.49 C ANISOU 543 CE1 TYR A 392 990 963 890 -39 -60 89 C ATOM 544 CE2 TYR A 392 45.491 -3.876 -11.812 1.00 7.41 C ANISOU 544 CE2 TYR A 392 976 967 870 -79 -73 90 C ATOM 545 CZ TYR A 392 45.026 -2.641 -12.213 1.00 7.35 C ANISOU 545 CZ TYR A 392 970 963 858 -64 -28 82 C ATOM 546 OH TYR A 392 45.935 -1.597 -12.362 1.00 7.92 O ANISOU 546 OH TYR A 392 1186 926 895 -129 -41 122 O ATOM 547 N PHE A 393 39.475 -6.889 -10.311 1.00 6.67 N ANISOU 547 N PHE A 393 950 822 759 15 -82 31 N ATOM 548 CA PHE A 393 38.504 -7.965 -10.455 1.00 7.10 C ANISOU 548 CA PHE A 393 961 899 838 -13 -110 0 C ATOM 549 C PHE A 393 38.167 -8.141 -11.919 1.00 6.85 C ANISOU 549 C PHE A 393 925 826 851 -49 -136 1 C ATOM 550 O PHE A 393 37.834 -7.165 -12.606 1.00 5.48 O ANISOU 550 O PHE A 393 652 637 792 -74 -163 -155 O ATOM 551 CB PHE A 393 37.213 -7.674 -9.697 1.00 7.74 C ANISOU 551 CB PHE A 393 946 1014 978 4 -80 25 C ATOM 552 CG PHE A 393 37.342 -7.675 -8.185 1.00 8.61 C ANISOU 552 CG PHE A 393 1092 1193 984 -8 -46 -37 C ATOM 553 CD1 PHE A 393 38.484 -8.158 -7.519 1.00 8.61 C ANISOU 553 CD1 PHE A 393 1068 1180 1022 -10 -34 -33 C ATOM 554 CD2 PHE A 393 36.266 -7.217 -7.412 1.00 8.75 C ANISOU 554 CD2 PHE A 393 1050 1191 1082 -79 -15 -49 C ATOM 555 CE1 PHE A 393 38.540 -8.149 -6.130 1.00 9.11 C ANISOU 555 CE1 PHE A 393 1119 1306 1035 -61 -26 -14 C ATOM 556 CE2 PHE A 393 36.328 -7.212 -6.029 1.00 8.63 C ANISOU 556 CE2 PHE A 393 1067 1127 1082 -112 -33 -30 C ATOM 557 CZ PHE A 393 37.463 -7.685 -5.390 1.00 8.88 C ANISOU 557 CZ PHE A 393 1147 1128 1097 -5 -58 -63 C ATOM 558 N ILE A 394 38.231 -9.388 -12.380 1.00 6.85 N ANISOU 558 N ILE A 394 892 847 861 -8 -88 -13 N ATOM 559 CA ILE A 394 37.749 -9.752 -13.707 1.00 7.09 C ANISOU 559 CA ILE A 394 958 869 864 -58 -44 -54 C ATOM 560 C ILE A 394 36.450 -10.535 -13.536 1.00 6.99 C ANISOU 560 C ILE A 394 959 834 860 -53 -58 -36 C ATOM 561 O ILE A 394 36.421 -11.548 -12.845 1.00 6.33 O ANISOU 561 O ILE A 394 862 711 832 -49 -206 -113 O ATOM 562 CB ILE A 394 38.841 -10.517 -14.481 1.00 7.46 C ANISOU 562 CB ILE A 394 949 927 958 0 -4 2 C ATOM 563 CG1 ILE A 394 40.058 -9.585 -14.595 1.00 7.67 C ANISOU 563 CG1 ILE A 394 1026 891 996 -31 21 -27 C ATOM 564 CG2 ILE A 394 38.334 -10.951 -15.852 1.00 7.31 C ANISOU 564 CG2 ILE A 394 960 890 926 -10 52 5 C ATOM 565 CD1 ILE A 394 41.341 -10.206 -15.034 1.00 7.91 C ANISOU 565 CD1 ILE A 394 997 956 1051 1 -13 -11 C ATOM 566 N PHE A 395 35.373 -10.027 -14.137 1.00 7.23 N ANISOU 566 N PHE A 395 999 817 931 -40 -82 -17 N ATOM 567 CA PHE A 395 34.028 -10.553 -13.908 1.00 7.52 C ANISOU 567 CA PHE A 395 970 955 929 6 -38 -7 C ATOM 568 C PHE A 395 33.661 -11.484 -15.050 1.00 7.46 C ANISOU 568 C PHE A 395 955 906 972 -23 -13 -19 C ATOM 569 O PHE A 395 33.677 -11.071 -16.225 1.00 7.00 O ANISOU 569 O PHE A 395 994 790 873 -4 -89 -149 O ATOM 570 CB PHE A 395 33.013 -9.406 -13.811 1.00 8.08 C ANISOU 570 CB PHE A 395 1053 960 1055 30 19 -21 C ATOM 571 CG PHE A 395 33.221 -8.519 -12.621 1.00 8.15 C ANISOU 571 CG PHE A 395 1066 977 1051 61 7 -28 C ATOM 572 CD1 PHE A 395 34.139 -7.466 -12.663 1.00 8.54 C ANISOU 572 CD1 PHE A 395 1155 1007 1083 11 4 -48 C ATOM 573 CD2 PHE A 395 32.503 -8.729 -11.457 1.00 8.41 C ANISOU 573 CD2 PHE A 395 1124 984 1085 55 37 -18 C ATOM 574 CE1 PHE A 395 34.328 -6.644 -11.557 1.00 8.55 C ANISOU 574 CE1 PHE A 395 1166 1008 1075 25 9 -38 C ATOM 575 CE2 PHE A 395 32.690 -7.915 -10.354 1.00 8.48 C ANISOU 575 CE2 PHE A 395 1054 1076 1092 69 9 -59 C ATOM 576 CZ PHE A 395 33.596 -6.865 -10.405 1.00 8.52 C ANISOU 576 CZ PHE A 395 1159 999 1080 70 12 -4 C ATOM 577 N VAL A 396 33.332 -12.727 -14.707 1.00 7.50 N ANISOU 577 N VAL A 396 996 894 960 65 6 30 N ATOM 578 CA VAL A 396 32.975 -13.757 -15.685 1.00 7.60 C ANISOU 578 CA VAL A 396 964 954 969 8 0 11 C ATOM 579 C VAL A 396 31.665 -14.435 -15.252 1.00 7.84 C ANISOU 579 C VAL A 396 997 972 1008 9 39 7 C ATOM 580 O VAL A 396 31.478 -14.718 -14.075 1.00 7.87 O ANISOU 580 O VAL A 396 886 1030 1072 -112 109 94 O ATOM 581 CB VAL A 396 34.132 -14.791 -15.817 1.00 7.63 C ANISOU 581 CB VAL A 396 957 953 989 0 -11 6 C ATOM 582 CG1 VAL A 396 33.767 -15.952 -16.724 1.00 7.61 C ANISOU 582 CG1 VAL A 396 904 1000 987 -16 -49 -6 C ATOM 583 CG2 VAL A 396 35.397 -14.119 -16.351 1.00 7.67 C ANISOU 583 CG2 VAL A 396 943 1002 968 -28 -33 -4 C ATOM 584 N ALA A 397 30.762 -14.676 -16.200 1.00 8.12 N ANISOU 584 N ALA A 397 1045 983 1057 37 -10 -14 N ATOM 585 CA ALA A 397 29.513 -15.387 -15.912 1.00 8.83 C ANISOU 585 CA ALA A 397 1098 1114 1141 -12 19 -22 C ATOM 586 C ALA A 397 29.839 -16.848 -15.612 1.00 9.55 C ANISOU 586 C ALA A 397 1238 1130 1261 3 -18 -36 C ATOM 587 O ALA A 397 30.548 -17.483 -16.380 1.00 9.05 O ANISOU 587 O ALA A 397 1377 917 1144 87 -125 -34 O ATOM 588 CB ALA A 397 28.561 -15.285 -17.081 1.00 8.58 C ANISOU 588 CB ALA A 397 1027 1068 1162 -2 26 -56 C ATOM 589 N GLN A 398 29.357 -17.352 -14.480 1.00 11.38 N ANISOU 589 N GLN A 398 1362 1552 1408 -201 108 19 N ATOM 590 CA GLN A 398 29.682 -18.713 -14.028 1.00 13.57 C ANISOU 590 CA GLN A 398 1686 1616 1851 -44 72 42 C ATOM 591 C GLN A 398 29.240 -19.785 -15.025 1.00 13.05 C ANISOU 591 C GLN A 398 1644 1616 1696 -194 226 131 C ATOM 592 O GLN A 398 29.979 -20.733 -15.292 1.00 13.77 O ANISOU 592 O GLN A 398 1716 1428 2086 -270 425 343 O ATOM 593 CB GLN A 398 29.027 -18.997 -12.675 1.00 16.50 C ANISOU 593 CB GLN A 398 2118 2301 1850 -135 124 25 C ATOM 594 CG GLN A 398 29.201 -20.422 -12.150 1.00 19.62 C ANISOU 594 CG GLN A 398 2793 2265 2395 -123 85 10 C ATOM 595 CD GLN A 398 30.610 -20.703 -11.661 1.00 22.80 C ANISOU 595 CD GLN A 398 2834 3013 2815 -209 -64 -297 C ATOM 596 OE1 GLN A 398 30.933 -20.406 -10.503 1.00 29.65 O ANISOU 596 OE1 GLN A 398 4508 4142 2613 -485 428 -640 O ATOM 597 NE2 GLN A 398 31.458 -21.283 -12.524 1.00 22.61 N ANISOU 597 NE2 GLN A 398 3070 2769 2750 -218 -194 -697 N ATOM 598 N GLN A 399 28.035 -19.630 -15.557 1.00 12.60 N ANISOU 598 N GLN A 399 1699 1617 1472 -49 249 216 N ATOM 599 CA GLN A 399 27.403 -20.667 -16.372 1.00 14.42 C ANISOU 599 CA GLN A 399 1988 1784 1704 -71 86 83 C ATOM 600 C GLN A 399 27.870 -20.654 -17.824 1.00 13.40 C ANISOU 600 C GLN A 399 1893 1553 1646 12 -21 42 C ATOM 601 O GLN A 399 27.942 -21.704 -18.452 1.00 16.13 O ANISOU 601 O GLN A 399 2552 1907 1666 209 -74 -232 O ATOM 602 CB GLN A 399 25.884 -20.505 -16.329 1.00 16.02 C ANISOU 602 CB GLN A 399 2008 2015 2062 -70 86 142 C ATOM 603 CG GLN A 399 25.315 -20.439 -14.920 1.00 19.32 C ANISOU 603 CG GLN A 399 2493 2574 2270 -63 355 75 C ATOM 604 N THR A 400 28.152 -19.468 -18.355 1.00 11.12 N ANISOU 604 N THR A 400 1334 1505 1385 -113 -43 -126 N ATOM 605 CA THR A 400 28.447 -19.281 -19.775 1.00 10.36 C ANISOU 605 CA THR A 400 1195 1320 1421 -109 -37 -40 C ATOM 606 C THR A 400 29.918 -18.970 -20.068 1.00 9.02 C ANISOU 606 C THR A 400 1267 1021 1136 -222 6 -47 C ATOM 607 O THR A 400 30.354 -19.151 -21.191 1.00 7.94 O ANISOU 607 O THR A 400 1144 809 1062 -657 -43 -113 O ATOM 608 CB THR A 400 27.617 -18.111 -20.337 1.00 10.94 C ANISOU 608 CB THR A 400 1316 1341 1498 -14 -36 -84 C ATOM 609 OG1 THR A 400 28.079 -16.899 -19.747 1.00 9.87 O ANISOU 609 OG1 THR A 400 877 1280 1591 175 -125 -103 O ATOM 610 CG2 THR A 400 26.134 -18.277 -20.012 1.00 11.59 C ANISOU 610 CG2 THR A 400 1342 1528 1531 -63 -49 -61 C ATOM 611 N TYR A 401 30.664 -18.505 -19.059 1.00 8.50 N ANISOU 611 N TYR A 401 1126 1001 1103 -123 16 -30 N ATOM 612 CA TYR A 401 32.025 -17.950 -19.231 1.00 8.33 C ANISOU 612 CA TYR A 401 1087 990 1089 -48 8 43 C ATOM 613 C TYR A 401 32.136 -16.727 -20.151 1.00 8.43 C ANISOU 613 C TYR A 401 1099 1020 1081 15 8 68 C ATOM 614 O TYR A 401 33.234 -16.395 -20.617 1.00 8.60 O ANISOU 614 O TYR A 401 1064 1143 1060 115 0 211 O ATOM 615 CB TYR A 401 33.045 -19.025 -19.641 1.00 8.57 C ANISOU 615 CB TYR A 401 1049 1096 1110 -11 21 51 C ATOM 616 CG TYR A 401 33.416 -20.032 -18.568 1.00 8.92 C ANISOU 616 CG TYR A 401 1086 1122 1180 29 39 106 C ATOM 617 CD1 TYR A 401 33.034 -19.880 -17.220 1.00 9.27 C ANISOU 617 CD1 TYR A 401 1109 1193 1220 105 108 157 C ATOM 618 CD2 TYR A 401 34.192 -21.137 -18.898 1.00 9.28 C ANISOU 618 CD2 TYR A 401 1047 1254 1221 103 108 151 C ATOM 619 CE1 TYR A 401 33.399 -20.827 -16.265 1.00 9.36 C ANISOU 619 CE1 TYR A 401 1090 1274 1192 191 135 165 C ATOM 620 CE2 TYR A 401 34.542 -22.085 -17.948 1.00 9.22 C ANISOU 620 CE2 TYR A 401 944 1318 1239 182 38 143 C ATOM 621 CZ TYR A 401 34.157 -21.920 -16.642 1.00 9.37 C ANISOU 621 CZ TYR A 401 1068 1236 1254 192 115 202 C ATOM 622 OH TYR A 401 34.540 -22.857 -15.713 1.00 10.38 O ANISOU 622 OH TYR A 401 1216 1435 1291 619 52 131 O ATOM 623 N ASN A 402 31.029 -16.017 -20.354 1.00 8.40 N ANISOU 623 N ASN A 402 1073 992 1124 -22 -45 86 N ATOM 624 CA ASN A 402 31.106 -14.687 -20.958 1.00 7.94 C ANISOU 624 CA ASN A 402 1062 942 1011 18 -12 24 C ATOM 625 C ASN A 402 31.895 -13.761 -20.030 1.00 7.37 C ANISOU 625 C ASN A 402 988 835 976 98 -9 31 C ATOM 626 O ASN A 402 31.707 -13.818 -18.812 1.00 6.65 O ANISOU 626 O ASN A 402 1011 550 964 29 -17 17 O ATOM 627 CB ASN A 402 29.722 -14.082 -21.183 1.00 8.29 C ANISOU 627 CB ASN A 402 1031 1040 1078 12 -6 60 C ATOM 628 CG ASN A 402 29.112 -14.456 -22.519 1.00 8.95 C ANISOU 628 CG ASN A 402 1177 1118 1104 38 -44 21 C ATOM 629 OD1 ASN A 402 29.521 -15.407 -23.175 1.00 9.59 O ANISOU 629 OD1 ASN A 402 1302 1203 1136 165 -68 31 O ATOM 630 ND2 ASN A 402 28.109 -13.698 -22.926 1.00 9.42 N ANISOU 630 ND2 ASN A 402 1154 1221 1203 102 -109 -145 N ATOM 631 N ALA A 403 32.777 -12.938 -20.603 1.00 7.09 N ANISOU 631 N ALA A 403 967 807 918 145 20 2 N ATOM 632 CA ALA A 403 33.438 -11.861 -19.857 1.00 7.48 C ANISOU 632 CA ALA A 403 939 935 969 59 -39 19 C ATOM 633 C ALA A 403 32.410 -10.752 -19.657 1.00 7.36 C ANISOU 633 C ALA A 403 954 899 944 40 -16 15 C ATOM 634 O ALA A 403 31.715 -10.388 -20.599 1.00 7.21 O ANISOU 634 O ALA A 403 862 969 908 85 -5 -66 O ATOM 635 CB ALA A 403 34.635 -11.325 -20.613 1.00 8.04 C ANISOU 635 CB ALA A 403 994 1059 998 39 -9 27 C ATOM 636 N LEU A 404 32.306 -10.250 -18.430 1.00 7.34 N ANISOU 636 N LEU A 404 932 929 925 -50 -44 14 N ATOM 637 CA LEU A 404 31.346 -9.212 -18.072 1.00 7.80 C ANISOU 637 CA LEU A 404 1016 916 1030 -31 -58 -19 C ATOM 638 C LEU A 404 32.003 -7.850 -17.848 1.00 7.84 C ANISOU 638 C LEU A 404 1011 907 1059 -42 -19 50 C ATOM 639 O LEU A 404 31.317 -6.830 -17.835 1.00 7.88 O ANISOU 639 O LEU A 404 1193 776 1026 -68 -17 257 O ATOM 640 CB LEU A 404 30.543 -9.627 -16.835 1.00 8.07 C ANISOU 640 CB LEU A 404 1035 994 1037 4 -33 -20 C ATOM 641 CG LEU A 404 29.814 -10.974 -16.972 1.00 8.78 C ANISOU 641 CG LEU A 404 1129 1034 1172 -44 -34 -16 C ATOM 642 CD1 LEU A 404 29.074 -11.324 -15.694 1.00 9.15 C ANISOU 642 CD1 LEU A 404 1144 1138 1194 -12 17 -70 C ATOM 643 CD2 LEU A 404 28.863 -10.978 -18.163 1.00 8.92 C ANISOU 643 CD2 LEU A 404 1177 1041 1169 -52 -44 -93 C ATOM 644 N GLY A 405 33.316 -7.850 -17.650 1.00 7.75 N ANISOU 644 N GLY A 405 1010 888 1045 -58 -42 85 N ATOM 645 CA GLY A 405 34.091 -6.624 -17.533 1.00 7.36 C ANISOU 645 CA GLY A 405 953 892 951 -29 -62 6 C ATOM 646 C GLY A 405 35.243 -6.820 -16.589 1.00 6.90 C ANISOU 646 C GLY A 405 963 761 896 -32 -43 33 C ATOM 647 O GLY A 405 35.450 -7.911 -16.058 1.00 6.20 O ANISOU 647 O GLY A 405 871 631 852 -135 -66 -48 O ATOM 648 N TYR A 406 36.020 -5.758 -16.402 1.00 6.58 N ANISOU 648 N TYR A 406 897 765 835 -14 -1 -1 N ATOM 649 CA TYR A 406 36.956 -5.738 -15.321 1.00 6.68 C ANISOU 649 CA TYR A 406 883 799 855 -8 -1 -35 C ATOM 650 C TYR A 406 37.041 -4.361 -14.719 1.00 7.06 C ANISOU 650 C TYR A 406 990 804 887 46 6 -53 C ATOM 651 O TYR A 406 36.715 -3.360 -15.376 1.00 7.50 O ANISOU 651 O TYR A 406 1239 789 820 73 20 -77 O ATOM 652 CB TYR A 406 38.319 -6.258 -15.753 1.00 6.70 C ANISOU 652 CB TYR A 406 845 837 862 -29 -13 -34 C ATOM 653 CG TYR A 406 39.074 -5.432 -16.771 1.00 6.73 C ANISOU 653 CG TYR A 406 852 825 880 -14 -9 -11 C ATOM 654 CD1 TYR A 406 38.816 -5.556 -18.133 1.00 6.50 C ANISOU 654 CD1 TYR A 406 834 758 877 0 -2 -5 C ATOM 655 CD2 TYR A 406 40.117 -4.579 -16.379 1.00 6.91 C ANISOU 655 CD2 TYR A 406 877 826 922 -37 -3 1 C ATOM 656 CE1 TYR A 406 39.548 -4.837 -19.080 1.00 6.39 C ANISOU 656 CE1 TYR A 406 807 772 846 3 0 -25 C ATOM 657 CE2 TYR A 406 40.841 -3.860 -17.330 1.00 7.14 C ANISOU 657 CE2 TYR A 406 888 908 914 -67 -2 3 C ATOM 658 CZ TYR A 406 40.551 -3.991 -18.668 1.00 6.79 C ANISOU 658 CZ TYR A 406 841 825 911 -45 -8 -18 C ATOM 659 OH TYR A 406 41.283 -3.277 -19.594 1.00 7.03 O ANISOU 659 OH TYR A 406 927 859 884 -179 -59 -64 O ATOM 660 N ALA A 407 37.462 -4.338 -13.458 1.00 7.18 N ANISOU 660 N ALA A 407 1011 811 906 72 -25 -13 N ATOM 661 CA ALA A 407 37.472 -3.126 -12.650 1.00 7.11 C ANISOU 661 CA ALA A 407 963 853 884 39 -28 -33 C ATOM 662 C ALA A 407 38.649 -3.147 -11.697 1.00 7.13 C ANISOU 662 C ALA A 407 958 864 885 52 -24 1 C ATOM 663 O ALA A 407 39.136 -4.214 -11.316 1.00 6.23 O ANISOU 663 O ALA A 407 585 951 828 149 -18 -75 O ATOM 664 CB ALA A 407 36.171 -3.015 -11.875 1.00 7.30 C ANISOU 664 CB ALA A 407 971 857 944 -16 2 -2 C ATOM 665 N GLN A 408 39.110 -1.969 -11.298 1.00 7.48 N ANISOU 665 N GLN A 408 958 951 930 -65 -3 3 N ATOM 666 CA GLN A 408 40.092 -1.928 -10.236 1.00 7.99 C ANISOU 666 CA GLN A 408 1007 995 1032 -8 -69 -55 C ATOM 667 C GLN A 408 39.360 -1.826 -8.916 1.00 7.96 C ANISOU 667 C GLN A 408 1030 961 1032 -64 -70 -72 C ATOM 668 O GLN A 408 38.341 -1.148 -8.819 1.00 8.21 O ANISOU 668 O GLN A 408 1069 1029 1018 -20 -92 -137 O ATOM 669 CB GLN A 408 41.020 -0.754 -10.414 1.00 9.01 C ANISOU 669 CB GLN A 408 1112 1115 1196 -89 -26 5 C ATOM 670 CG GLN A 408 42.135 -0.739 -9.394 1.00 9.64 C ANISOU 670 CG GLN A 408 1213 1184 1264 -95 -104 49 C ATOM 671 CD GLN A 408 43.102 0.367 -9.655 1.00 11.28 C ANISOU 671 CD GLN A 408 1415 1369 1502 -260 -140 194 C ATOM 672 OE1 GLN A 408 42.992 1.067 -10.669 1.00 12.22 O ANISOU 672 OE1 GLN A 408 1535 1324 1783 -434 -380 374 O ATOM 673 NE2 GLN A 408 44.061 0.546 -8.746 1.00 11.97 N ANISOU 673 NE2 GLN A 408 1431 1435 1678 -130 -260 180 N ATOM 674 N VAL A 409 39.891 -2.492 -7.900 1.00 7.68 N ANISOU 674 N VAL A 409 1012 807 1098 -43 -64 -87 N ATOM 675 CA VAL A 409 39.396 -2.348 -6.543 1.00 8.20 C ANISOU 675 CA VAL A 409 1091 951 1072 -1 -84 -25 C ATOM 676 C VAL A 409 39.931 -0.997 -6.037 1.00 8.41 C ANISOU 676 C VAL A 409 1165 935 1093 -32 -100 6 C ATOM 677 O VAL A 409 41.137 -0.787 -6.025 1.00 7.64 O ANISOU 677 O VAL A 409 1122 647 1131 115 -120 -120 O ATOM 678 CB VAL A 409 39.880 -3.509 -5.647 1.00 8.32 C ANISOU 678 CB VAL A 409 1080 956 1123 35 -29 0 C ATOM 679 CG1 VAL A 409 39.408 -3.322 -4.215 1.00 8.54 C ANISOU 679 CG1 VAL A 409 1131 1021 1092 19 -85 7 C ATOM 680 CG2 VAL A 409 39.366 -4.826 -6.201 1.00 8.19 C ANISOU 680 CG2 VAL A 409 1033 991 1087 1 5 -6 C ATOM 681 N VAL A 410 39.040 -0.091 -5.637 1.00 8.80 N ANISOU 681 N VAL A 410 1158 1037 1147 -6 -52 56 N ATOM 682 CA VAL A 410 39.457 1.245 -5.171 1.00 9.83 C ANISOU 682 CA VAL A 410 1315 1133 1287 -87 -99 -38 C ATOM 683 C VAL A 410 39.121 1.537 -3.705 1.00 10.89 C ANISOU 683 C VAL A 410 1564 1297 1275 -138 -102 -5 C ATOM 684 O VAL A 410 39.330 2.658 -3.216 1.00 11.37 O ANISOU 684 O VAL A 410 1671 1266 1380 -231 -179 37 O ATOM 685 CB VAL A 410 38.956 2.376 -6.114 1.00 10.04 C ANISOU 685 CB VAL A 410 1279 1255 1280 -50 -63 10 C ATOM 686 CG1 VAL A 410 39.550 2.187 -7.503 1.00 10.50 C ANISOU 686 CG1 VAL A 410 1351 1350 1289 -110 -48 -31 C ATOM 687 CG2 VAL A 410 37.442 2.454 -6.191 1.00 9.94 C ANISOU 687 CG2 VAL A 410 1257 1262 1257 -107 -22 29 C ATOM 688 N SER A 411 38.610 0.527 -3.006 1.00 12.61 N ANISOU 688 N SER A 411 1829 1466 1495 -408 -103 25 N ATOM 689 CA SER A 411 38.545 0.543 -1.552 1.00 13.26 C ANISOU 689 CA SER A 411 1943 1606 1489 -300 -175 67 C ATOM 690 C SER A 411 38.821 -0.849 -1.009 1.00 12.04 C ANISOU 690 C SER A 411 1759 1529 1286 -284 -214 -59 C ATOM 691 O SER A 411 38.498 -1.870 -1.641 1.00 12.71 O ANISOU 691 O SER A 411 1901 1651 1277 -609 -216 -5 O ATOM 692 CB SER A 411 37.178 1.005 -1.056 1.00 14.73 C ANISOU 692 CB SER A 411 1986 1881 1729 -319 -89 14 C ATOM 693 OG SER A 411 36.294 -0.096 -0.931 1.00 16.94 O ANISOU 693 OG SER A 411 2583 2204 1648 -710 -147 244 O ATOM 694 N ASP A 412 39.385 -0.877 0.191 1.00 10.43 N ANISOU 694 N ASP A 412 1514 1248 1199 -171 -92 11 N ATOM 695 CA ASP A 412 39.565 -2.115 0.930 1.00 9.90 C ANISOU 695 CA ASP A 412 1388 1175 1197 -112 -51 -59 C ATOM 696 C ASP A 412 38.184 -2.581 1.380 1.00 8.91 C ANISOU 696 C ASP A 412 1343 1040 1003 -70 -106 -42 C ATOM 697 O ASP A 412 37.201 -1.845 1.277 1.00 7.43 O ANISOU 697 O ASP A 412 1382 803 637 -160 -236 20 O ATOM 698 CB ASP A 412 40.452 -1.868 2.155 1.00 10.15 C ANISOU 698 CB ASP A 412 1394 1221 1239 -1 -106 -46 C ATOM 699 CG ASP A 412 41.210 -3.093 2.618 1.00 10.38 C ANISOU 699 CG ASP A 412 1498 1173 1273 -75 -155 12 C ATOM 700 OD1 ASP A 412 40.923 -4.244 2.203 1.00 11.20 O ANISOU 700 OD1 ASP A 412 1436 1313 1506 -143 -226 -182 O ATOM 701 OD2 ASP A 412 42.140 -2.870 3.411 1.00 10.78 O ANISOU 701 OD2 ASP A 412 1737 1150 1208 -74 -311 178 O ATOM 702 N LEU A 413 38.140 -3.805 1.891 1.00 8.65 N ANISOU 702 N LEU A 413 1209 1035 1041 -47 -49 -19 N ATOM 703 CA LEU A 413 36.950 -4.379 2.490 1.00 8.80 C ANISOU 703 CA LEU A 413 1168 1090 1085 37 23 -27 C ATOM 704 C LEU A 413 36.406 -3.465 3.583 1.00 8.78 C ANISOU 704 C LEU A 413 1247 945 1142 -11 -35 -65 C ATOM 705 O LEU A 413 37.161 -2.920 4.365 1.00 8.42 O ANISOU 705 O LEU A 413 1370 758 1070 3 -13 -103 O ATOM 706 CB LEU A 413 37.282 -5.740 3.114 1.00 8.83 C ANISOU 706 CB LEU A 413 1158 1116 1081 28 34 21 C ATOM 707 CG LEU A 413 36.131 -6.629 3.554 1.00 9.39 C ANISOU 707 CG LEU A 413 1189 1175 1204 -17 3 26 C ATOM 708 CD1 LEU A 413 35.340 -7.141 2.352 1.00 10.03 C ANISOU 708 CD1 LEU A 413 1330 1280 1201 -74 -1 9 C ATOM 709 CD2 LEU A 413 36.678 -7.779 4.379 1.00 9.29 C ANISOU 709 CD2 LEU A 413 1169 1147 1211 -50 11 43 C ATOM 710 N ASN A 414 35.095 -3.330 3.635 1.00 9.19 N ANISOU 710 N ASN A 414 1248 1034 1210 75 19 -31 N ATOM 711 CA ASN A 414 34.466 -2.563 4.693 1.00 10.17 C ANISOU 711 CA ASN A 414 1341 1245 1275 73 18 -137 C ATOM 712 C ASN A 414 33.044 -3.059 4.930 1.00 10.36 C ANISOU 712 C ASN A 414 1338 1245 1350 56 31 -101 C ATOM 713 O ASN A 414 32.457 -3.714 4.076 1.00 9.45 O ANISOU 713 O ASN A 414 1116 1405 1066 114 157 -84 O ATOM 714 CB ASN A 414 34.473 -1.080 4.335 1.00 10.76 C ANISOU 714 CB ASN A 414 1372 1274 1440 30 46 -79 C ATOM 715 CG ASN A 414 33.490 -0.747 3.238 1.00 11.28 C ANISOU 715 CG ASN A 414 1385 1361 1537 106 14 -85 C ATOM 716 OD1 ASN A 414 32.339 -0.417 3.515 1.00 11.80 O ANISOU 716 OD1 ASN A 414 1514 1113 1856 216 147 -227 O ATOM 717 ND2 ASN A 414 33.923 -0.852 1.996 1.00 11.89 N ANISOU 717 ND2 ASN A 414 1538 1430 1547 120 35 -197 N ATOM 718 N SER A 415 32.507 -2.731 6.095 1.00 11.20 N ANISOU 718 N SER A 415 1589 1395 1270 30 -27 -150 N ATOM 719 CA SER A 415 31.156 -3.103 6.482 1.00 12.74 C ANISOU 719 CA SER A 415 1620 1647 1573 -79 57 -252 C ATOM 720 C SER A 415 30.200 -1.904 6.460 1.00 13.78 C ANISOU 720 C SER A 415 1649 1814 1772 -7 88 -340 C ATOM 721 O SER A 415 29.066 -2.011 6.915 1.00 14.53 O ANISOU 721 O SER A 415 1632 2041 1849 -225 77 -361 O ATOM 722 CB SER A 415 31.191 -3.720 7.879 1.00 13.30 C ANISOU 722 CB SER A 415 1794 1657 1601 -93 72 -279 C ATOM 723 OG SER A 415 31.742 -2.819 8.826 1.00 14.07 O ANISOU 723 OG SER A 415 1920 1709 1715 69 301 -641 O ATOM 724 N THR A 416 30.661 -0.775 5.924 1.00 14.85 N ANISOU 724 N THR A 416 1910 1902 1827 -64 110 -272 N ATOM 725 CA THR A 416 29.901 0.472 5.924 1.00 16.56 C ANISOU 725 CA THR A 416 2042 2096 2153 64 -125 -437 C ATOM 726 C THR A 416 29.045 0.611 4.685 1.00 17.88 C ANISOU 726 C THR A 416 2165 2400 2227 254 -179 -341 C ATOM 727 O THR A 416 27.960 1.157 4.758 1.00 18.57 O ANISOU 727 O THR A 416 2192 2845 2019 367 -32 -907 O ATOM 728 CB THR A 416 30.847 1.686 6.038 1.00 16.44 C ANISOU 728 CB THR A 416 2078 2063 2104 16 -102 -256 C ATOM 729 OG1 THR A 416 31.512 1.624 7.303 1.00 15.28 O ANISOU 729 OG1 THR A 416 1400 1796 2607 7 -446 -549 O ATOM 730 CG2 THR A 416 30.089 3.025 5.930 1.00 16.38 C ANISOU 730 CG2 THR A 416 1954 2140 2127 64 -179 -400 C ATOM 731 N GLU A 417 29.534 0.109 3.558 1.00 18.74 N ANISOU 731 N GLU A 417 2400 2309 2410 112 6 -436 N ATOM 732 CA GLU A 417 28.908 0.331 2.279 1.00 19.86 C ANISOU 732 CA GLU A 417 2566 2550 2430 57 -9 -318 C ATOM 733 C GLU A 417 28.724 -1.020 1.574 1.00 18.76 C ANISOU 733 C GLU A 417 2353 2580 2192 57 293 -312 C ATOM 734 O GLU A 417 29.609 -1.473 0.863 1.00 17.76 O ANISOU 734 O GLU A 417 2230 2256 2260 27 347 -217 O ATOM 735 CB GLU A 417 29.808 1.290 1.502 1.00 23.64 C ANISOU 735 CB GLU A 417 2931 2885 3166 -128 99 -23 C ATOM 736 CG GLU A 417 29.283 1.752 0.167 1.00 27.58 C ANISOU 736 CG GLU A 417 3421 3579 3477 -136 -273 103 C ATOM 737 CD GLU A 417 30.110 2.894 -0.399 1.00 32.25 C ANISOU 737 CD GLU A 417 4002 3717 4532 -132 -281 677 C ATOM 738 OE1 GLU A 417 31.367 2.811 -0.353 1.00 38.35 O ANISOU 738 OE1 GLU A 417 4024 5457 5087 -392 -982 736 O ATOM 739 OE2 GLU A 417 29.508 3.868 -0.892 1.00 36.04 O ANISOU 739 OE2 GLU A 417 4587 4045 5058 841 -383 233 O ATOM 740 N LEU A 418 27.573 -1.660 1.814 1.00 18.21 N ANISOU 740 N LEU A 418 2433 2634 1850 -113 65 -208 N ATOM 741 CA LEU A 418 27.249 -2.980 1.264 1.00 18.71 C ANISOU 741 CA LEU A 418 2424 2509 2175 72 -68 -208 C ATOM 742 C LEU A 418 26.174 -2.881 0.166 1.00 17.73 C ANISOU 742 C LEU A 418 2296 2213 2228 113 -49 -263 C ATOM 743 O LEU A 418 25.240 -2.091 0.298 1.00 19.04 O ANISOU 743 O LEU A 418 2141 2805 2287 216 -70 -886 O ATOM 744 CB LEU A 418 26.721 -3.896 2.372 1.00 21.28 C ANISOU 744 CB LEU A 418 2808 2695 2582 -17 -20 9 C ATOM 745 CG LEU A 418 27.562 -4.056 3.640 1.00 23.89 C ANISOU 745 CG LEU A 418 3211 3109 2755 187 -174 13 C ATOM 746 CD1 LEU A 418 26.786 -4.913 4.633 1.00 27.18 C ANISOU 746 CD1 LEU A 418 3747 3275 3302 69 39 175 C ATOM 747 CD2 LEU A 418 28.931 -4.659 3.345 1.00 23.38 C ANISOU 747 CD2 LEU A 418 3153 2825 2902 144 -156 78 C ATOM 748 N PRO A 419 26.285 -3.688 -0.918 1.00 17.12 N ANISOU 748 N PRO A 419 2112 2286 2107 127 -98 -221 N ATOM 749 CA PRO A 419 25.157 -3.733 -1.870 1.00 17.20 C ANISOU 749 CA PRO A 419 2280 2279 1976 122 -124 -236 C ATOM 750 C PRO A 419 23.913 -4.349 -1.228 1.00 15.97 C ANISOU 750 C PRO A 419 2179 2113 1773 197 -142 -286 C ATOM 751 O PRO A 419 24.041 -5.234 -0.392 1.00 13.25 O ANISOU 751 O PRO A 419 1688 2059 1287 429 13 -519 O ATOM 752 CB PRO A 419 25.655 -4.662 -2.989 1.00 17.23 C ANISOU 752 CB PRO A 419 2238 2291 2015 87 -48 -208 C ATOM 753 CG PRO A 419 27.065 -4.971 -2.696 1.00 17.13 C ANISOU 753 CG PRO A 419 2280 2143 2083 204 -21 -117 C ATOM 754 CD PRO A 419 27.330 -4.665 -1.258 1.00 16.89 C ANISOU 754 CD PRO A 419 2268 2109 2039 126 17 -82 C ATOM 755 N PHE A 420 22.721 -3.929 -1.645 1.00 16.51 N ANISOU 755 N PHE A 420 2229 2131 1914 267 -104 -166 N ATOM 756 CA PHE A 420 21.482 -4.521 -1.114 1.00 18.94 C ANISOU 756 CA PHE A 420 2442 2462 2292 2 -47 -105 C ATOM 757 C PHE A 420 21.435 -6.042 -1.307 1.00 17.53 C ANISOU 757 C PHE A 420 2170 2446 2044 -55 4 -6 C ATOM 758 O PHE A 420 20.781 -6.742 -0.543 1.00 20.31 O ANISOU 758 O PHE A 420 2305 2996 2415 -136 523 10 O ATOM 759 CB PHE A 420 20.237 -3.877 -1.745 1.00 20.04 C ANISOU 759 CB PHE A 420 2392 2708 2513 57 -11 -175 C ATOM 760 CG PHE A 420 19.912 -4.392 -3.122 1.00 21.72 C ANISOU 760 CG PHE A 420 2644 3133 2474 -78 -154 -101 C ATOM 761 CD1 PHE A 420 19.108 -5.520 -3.288 1.00 23.40 C ANISOU 761 CD1 PHE A 420 3026 3177 2684 -221 -101 -136 C ATOM 762 CD2 PHE A 420 20.418 -3.765 -4.243 1.00 23.19 C ANISOU 762 CD2 PHE A 420 3069 3158 2584 -178 -93 15 C ATOM 763 CE1 PHE A 420 18.812 -6.005 -4.554 1.00 23.52 C ANISOU 763 CE1 PHE A 420 2831 3428 2678 -72 -123 -154 C ATOM 764 CE2 PHE A 420 20.122 -4.245 -5.512 1.00 24.36 C ANISOU 764 CE2 PHE A 420 3069 3392 2793 -169 -251 -199 C ATOM 765 CZ PHE A 420 19.322 -5.364 -5.664 1.00 22.41 C ANISOU 765 CZ PHE A 420 2867 2976 2673 136 -198 -57 C ATOM 766 N TRP A 421 22.121 -6.530 -2.339 1.00 16.31 N ANISOU 766 N TRP A 421 1661 2394 2141 -59 -84 -23 N ATOM 767 CA TRP A 421 22.120 -7.956 -2.706 1.00 17.45 C ANISOU 767 CA TRP A 421 1974 2392 2263 -123 -44 -48 C ATOM 768 C TRP A 421 23.055 -8.869 -1.918 1.00 17.14 C ANISOU 768 C TRP A 421 2004 2132 2376 -210 -47 -55 C ATOM 769 O TRP A 421 23.041 -10.078 -2.143 1.00 20.09 O ANISOU 769 O TRP A 421 2436 2254 2941 -794 -24 -404 O ATOM 770 CB TRP A 421 22.389 -8.136 -4.211 1.00 17.16 C ANISOU 770 CB TRP A 421 1998 2247 2275 -78 20 -119 C ATOM 771 CG TRP A 421 23.613 -7.444 -4.783 1.00 16.95 C ANISOU 771 CG TRP A 421 2083 2185 2171 -43 163 -204 C ATOM 772 CD1 TRP A 421 23.669 -6.193 -5.338 1.00 16.93 C ANISOU 772 CD1 TRP A 421 2057 2286 2088 -65 247 -141 C ATOM 773 CD2 TRP A 421 24.929 -7.993 -4.907 1.00 16.71 C ANISOU 773 CD2 TRP A 421 2087 2163 2100 -45 40 -101 C ATOM 774 NE1 TRP A 421 24.950 -5.920 -5.773 1.00 16.87 N ANISOU 774 NE1 TRP A 421 2045 2328 2036 -39 237 -112 N ATOM 775 CE2 TRP A 421 25.737 -7.015 -5.531 1.00 17.06 C ANISOU 775 CE2 TRP A 421 2073 2247 2159 -95 83 -131 C ATOM 776 CE3 TRP A 421 25.501 -9.220 -4.558 1.00 16.89 C ANISOU 776 CE3 TRP A 421 2170 2192 2053 27 7 -170 C ATOM 777 CZ2 TRP A 421 27.090 -7.228 -5.800 1.00 16.89 C ANISOU 777 CZ2 TRP A 421 2115 2157 2142 14 105 5 C ATOM 778 CZ3 TRP A 421 26.840 -9.429 -4.826 1.00 17.19 C ANISOU 778 CZ3 TRP A 421 2159 2236 2136 72 -11 -72 C ATOM 779 CH2 TRP A 421 27.617 -8.439 -5.443 1.00 17.37 C ANISOU 779 CH2 TRP A 421 2162 2122 2315 65 54 -177 C ATOM 780 N SER A 422 23.877 -8.326 -1.023 1.00 17.55 N ANISOU 780 N SER A 422 2223 2259 2183 -137 -66 -170 N ATOM 781 CA SER A 422 24.784 -9.179 -0.250 1.00 17.92 C ANISOU 781 CA SER A 422 2280 2115 2413 -54 -26 -188 C ATOM 782 C SER A 422 24.026 -10.029 0.772 1.00 18.73 C ANISOU 782 C SER A 422 2258 2408 2447 -179 -41 -118 C ATOM 783 O SER A 422 22.964 -9.649 1.246 1.00 19.93 O ANISOU 783 O SER A 422 2316 2679 2577 -377 257 -91 O ATOM 784 CB SER A 422 25.871 -8.359 0.438 1.00 18.45 C ANISOU 784 CB SER A 422 2312 2500 2195 38 -106 -342 C ATOM 785 OG SER A 422 25.302 -7.436 1.330 1.00 20.55 O ANISOU 785 OG SER A 422 2719 2349 2738 172 -289 -684 O ATOM 786 N ASP A 423 24.627 -11.162 1.113 1.00 18.57 N ANISOU 786 N ASP A 423 2269 2283 2501 -332 -47 -106 N ATOM 787 CA ASP A 423 24.040 -12.223 1.915 1.00 19.37 C ANISOU 787 CA ASP A 423 2459 2456 2444 -208 102 41 C ATOM 788 C ASP A 423 25.156 -12.853 2.759 1.00 17.60 C ANISOU 788 C ASP A 423 2331 2171 2184 -178 328 -47 C ATOM 789 O ASP A 423 26.292 -12.354 2.776 1.00 16.91 O ANISOU 789 O ASP A 423 1974 2251 2199 209 668 24 O ATOM 790 CB ASP A 423 23.304 -13.248 1.004 1.00 21.04 C ANISOU 790 CB ASP A 423 2836 2439 2718 -199 -88 -5 C ATOM 791 CG ASP A 423 24.224 -13.957 0.010 1.00 22.11 C ANISOU 791 CG ASP A 423 2867 3002 2531 -393 150 105 C ATOM 792 OD1 ASP A 423 25.418 -14.183 0.299 1.00 23.05 O ANISOU 792 OD1 ASP A 423 2914 3270 2572 -125 218 -35 O ATOM 793 OD2 ASP A 423 23.732 -14.326 -1.076 1.00 28.12 O ANISOU 793 OD2 ASP A 423 3208 4234 3242 -995 -500 8 O ATOM 794 N SER A 424 24.836 -13.951 3.435 1.00 17.42 N ANISOU 794 N SER A 424 2235 2094 2288 -61 447 -38 N ATOM 795 CA SER A 424 25.726 -14.579 4.402 1.00 17.52 C ANISOU 795 CA SER A 424 2090 2155 2410 -187 310 -52 C ATOM 796 C SER A 424 27.010 -15.179 3.824 1.00 15.67 C ANISOU 796 C SER A 424 1976 1749 2228 -237 170 22 C ATOM 797 O SER A 424 27.892 -15.531 4.586 1.00 15.87 O ANISOU 797 O SER A 424 1729 1777 2522 -7 337 164 O ATOM 798 CB SER A 424 24.967 -15.690 5.138 1.00 20.35 C ANISOU 798 CB SER A 424 2809 2355 2566 -438 238 153 C ATOM 799 OG SER A 424 24.602 -16.715 4.226 1.00 24.17 O ANISOU 799 OG SER A 424 3412 2640 3131 -954 365 -125 O ATOM 800 N SER A 425 27.104 -15.324 2.502 1.00 15.53 N ANISOU 800 N SER A 425 1822 1800 2277 -152 224 -41 N ATOM 801 CA SER A 425 28.348 -15.779 1.847 1.00 14.80 C ANISOU 801 CA SER A 425 1799 1702 2121 -54 111 -65 C ATOM 802 C SER A 425 29.426 -14.693 1.735 1.00 13.76 C ANISOU 802 C SER A 425 1798 1536 1894 7 29 -102 C ATOM 803 O SER A 425 30.590 -14.995 1.417 1.00 12.39 O ANISOU 803 O SER A 425 1624 1342 1742 -270 -145 -166 O ATOM 804 CB SER A 425 28.032 -16.335 0.454 1.00 16.02 C ANISOU 804 CB SER A 425 2093 1907 2084 -76 211 -85 C ATOM 805 OG SER A 425 27.514 -15.347 -0.416 1.00 15.48 O ANISOU 805 OG SER A 425 1754 1960 2165 138 90 -309 O ATOM 806 N HIS A 426 29.038 -13.443 1.984 1.00 13.24 N ANISOU 806 N HIS A 426 1702 1568 1759 -23 86 -205 N ATOM 807 CA HIS A 426 29.893 -12.267 1.799 1.00 12.82 C ANISOU 807 CA HIS A 426 1545 1726 1599 -59 101 -98 C ATOM 808 C HIS A 426 30.448 -11.730 3.105 1.00 12.10 C ANISOU 808 C HIS A 426 1412 1563 1621 -72 155 -104 C ATOM 809 O HIS A 426 29.739 -11.709 4.119 1.00 13.32 O ANISOU 809 O HIS A 426 1517 1943 1600 -364 197 -273 O ATOM 810 CB HIS A 426 29.088 -11.161 1.115 1.00 13.13 C ANISOU 810 CB HIS A 426 1647 1654 1684 -112 122 -28 C ATOM 811 CG HIS A 426 28.647 -11.517 -0.266 1.00 14.28 C ANISOU 811 CG HIS A 426 1858 1877 1690 -31 44 -71 C ATOM 812 ND1 HIS A 426 27.324 -11.607 -0.629 1.00 15.02 N ANISOU 812 ND1 HIS A 426 1935 1977 1793 -35 21 -232 N ATOM 813 CD2 HIS A 426 29.357 -11.816 -1.376 1.00 15.17 C ANISOU 813 CD2 HIS A 426 1874 2103 1786 16 86 -148 C ATOM 814 CE1 HIS A 426 27.232 -11.937 -1.904 1.00 15.39 C ANISOU 814 CE1 HIS A 426 2031 2076 1741 35 29 -142 C ATOM 815 NE2 HIS A 426 28.455 -12.074 -2.379 1.00 15.51 N ANISOU 815 NE2 HIS A 426 1998 2117 1776 -12 35 -147 N ATOM 816 N ALA A 427 31.703 -11.269 3.066 1.00 10.31 N ANISOU 816 N ALA A 427 1373 1075 1466 29 110 -77 N ATOM 817 CA ALA A 427 32.375 -10.711 4.240 1.00 10.85 C ANISOU 817 CA ALA A 427 1410 1258 1453 -29 70 -33 C ATOM 818 C ALA A 427 32.117 -9.215 4.380 1.00 10.17 C ANISOU 818 C ALA A 427 1325 1233 1304 -106 57 -42 C ATOM 819 O ALA A 427 32.117 -8.686 5.481 1.00 10.20 O ANISOU 819 O ALA A 427 1199 1494 1180 -342 152 4 O ATOM 820 CB ALA A 427 33.868 -10.954 4.165 1.00 11.13 C ANISOU 820 CB ALA A 427 1387 1359 1481 -68 59 -10 C ATOM 821 N GLY A 428 31.926 -8.533 3.264 1.00 9.67 N ANISOU 821 N GLY A 428 1272 1098 1303 -121 61 -67 N ATOM 822 CA GLY A 428 31.706 -7.088 3.283 1.00 9.99 C ANISOU 822 CA GLY A 428 1365 1115 1315 -22 27 -35 C ATOM 823 C GLY A 428 31.777 -6.551 1.880 1.00 9.87 C ANISOU 823 C GLY A 428 1393 1012 1345 28 1 -4 C ATOM 824 O GLY A 428 31.696 -7.308 0.920 1.00 10.05 O ANISOU 824 O GLY A 428 1574 710 1535 27 122 -20 O ATOM 825 N GLY A 429 31.922 -5.237 1.743 1.00 9.24 N ANISOU 825 N GLY A 429 1243 1003 1263 43 -26 -27 N ATOM 826 CA GLY A 429 31.868 -4.631 0.419 1.00 8.98 C ANISOU 826 CA GLY A 429 1230 919 1262 32 4 -30 C ATOM 827 C GLY A 429 33.198 -4.040 0.044 1.00 8.80 C ANISOU 827 C GLY A 429 1099 1072 1171 131 -21 -59 C ATOM 828 O GLY A 429 34.042 -3.839 0.911 1.00 8.64 O ANISOU 828 O GLY A 429 1025 1052 1206 251 -39 -80 O ATOM 829 N VAL A 430 33.362 -3.772 -1.251 1.00 9.02 N ANISOU 829 N VAL A 430 1176 1115 1133 88 -74 -74 N ATOM 830 CA VAL A 430 34.445 -2.944 -1.785 1.00 9.29 C ANISOU 830 CA VAL A 430 1213 1149 1167 83 -98 9 C ATOM 831 C VAL A 430 33.889 -2.014 -2.859 1.00 9.27 C ANISOU 831 C VAL A 430 1216 1142 1163 101 -121 -15 C ATOM 832 O VAL A 430 32.882 -2.329 -3.499 1.00 9.33 O ANISOU 832 O VAL A 430 1479 1012 1055 144 -320 -38 O ATOM 833 CB VAL A 430 35.596 -3.751 -2.436 1.00 9.31 C ANISOU 833 CB VAL A 430 1205 1130 1199 39 -57 -9 C ATOM 834 CG1 VAL A 430 36.344 -4.563 -1.378 1.00 10.05 C ANISOU 834 CG1 VAL A 430 1345 1142 1331 53 -79 77 C ATOM 835 CG2 VAL A 430 35.093 -4.624 -3.576 1.00 8.95 C ANISOU 835 CG2 VAL A 430 1160 1080 1160 -9 29 9 C ATOM 836 N ARG A 431 34.557 -0.885 -3.044 1.00 9.25 N ANISOU 836 N ARG A 431 1191 1135 1186 104 -21 -42 N ATOM 837 CA ARG A 431 34.258 0.008 -4.156 1.00 10.20 C ANISOU 837 CA ARG A 431 1334 1256 1286 61 24 83 C ATOM 838 C ARG A 431 35.163 -0.416 -5.295 1.00 9.27 C ANISOU 838 C ARG A 431 1267 980 1274 56 -36 63 C ATOM 839 O ARG A 431 36.336 -0.753 -5.073 1.00 8.82 O ANISOU 839 O ARG A 431 1256 880 1215 99 56 111 O ATOM 840 CB ARG A 431 34.558 1.455 -3.796 1.00 12.64 C ANISOU 840 CB ARG A 431 1732 1330 1738 -53 -97 25 C ATOM 841 CG ARG A 431 33.736 2.038 -2.665 1.00 15.82 C ANISOU 841 CG ARG A 431 2043 1998 1968 62 51 -90 C ATOM 842 CD ARG A 431 34.109 3.511 -2.459 1.00 21.09 C ANISOU 842 CD ARG A 431 2838 2076 3098 -72 -99 -90 C ATOM 843 NE ARG A 431 33.197 4.222 -1.557 1.00 27.81 N ANISOU 843 NE ARG A 431 3758 3453 3353 81 428 -417 N ATOM 844 CZ ARG A 431 33.077 5.555 -1.474 1.00 33.31 C ANISOU 844 CZ ARG A 431 4552 3609 4495 238 349 -521 C ATOM 845 NH1 ARG A 431 33.812 6.376 -2.232 1.00 36.41 N ANISOU 845 NH1 ARG A 431 4595 4300 4939 -3 172 -42 N ATOM 846 NH2 ARG A 431 32.203 6.081 -0.621 1.00 38.62 N ANISOU 846 NH2 ARG A 431 4974 4956 4744 315 803 -648 N ATOM 847 N ILE A 432 34.620 -0.408 -6.505 1.00 9.31 N ANISOU 847 N ILE A 432 1269 1006 1262 186 -32 23 N ATOM 848 CA ILE A 432 35.390 -0.713 -7.712 1.00 9.64 C ANISOU 848 CA ILE A 432 1266 1121 1273 89 -26 -46 C ATOM 849 C ILE A 432 35.324 0.457 -8.688 1.00 9.96 C ANISOU 849 C ILE A 432 1340 1205 1238 146 -68 -31 C ATOM 850 O ILE A 432 34.418 1.288 -8.606 1.00 11.36 O ANISOU 850 O ILE A 432 1715 1261 1338 395 -63 -49 O ATOM 851 CB ILE A 432 34.908 -2.024 -8.386 1.00 9.33 C ANISOU 851 CB ILE A 432 1237 1129 1180 54 -12 -30 C ATOM 852 CG1 ILE A 432 33.445 -1.900 -8.845 1.00 9.59 C ANISOU 852 CG1 ILE A 432 1245 1122 1277 111 -29 -22 C ATOM 853 CG2 ILE A 432 35.104 -3.191 -7.420 1.00 9.03 C ANISOU 853 CG2 ILE A 432 1132 1131 1166 72 -11 -39 C ATOM 854 CD1 ILE A 432 32.890 -3.097 -9.591 1.00 9.76 C ANISOU 854 CD1 ILE A 432 1257 1217 1231 65 -59 -24 C ATOM 855 N LYS A 433 36.301 0.519 -9.590 1.00 10.86 N ANISOU 855 N LYS A 433 1433 1379 1314 50 16 -81 N ATOM 856 CA LYS A 433 36.305 1.479 -10.701 1.00 11.70 C ANISOU 856 CA LYS A 433 1633 1457 1355 140 -7 -32 C ATOM 857 C LYS A 433 36.334 0.686 -11.993 1.00 10.36 C ANISOU 857 C LYS A 433 1317 1356 1262 54 -7 54 C ATOM 858 O LYS A 433 37.349 0.077 -12.330 1.00 9.47 O ANISOU 858 O LYS A 433 1393 1184 1021 139 -107 85 O ATOM 859 CB LYS A 433 37.515 2.415 -10.629 1.00 14.05 C ANISOU 859 CB LYS A 433 1808 1748 1780 -52 45 -59 C ATOM 860 CG LYS A 433 37.551 3.434 -11.756 1.00 17.10 C ANISOU 860 CG LYS A 433 2416 2127 1953 57 82 161 C ATOM 861 CD LYS A 433 38.491 4.593 -11.457 1.00 21.40 C ANISOU 861 CD LYS A 433 2750 2692 2688 -329 24 133 C ATOM 862 CE LYS A 433 38.128 5.833 -12.268 1.00 25.17 C ANISOU 862 CE LYS A 433 3348 3044 3171 324 -127 233 C ATOM 863 NZ LYS A 433 38.160 5.580 -13.738 1.00 27.70 N ANISOU 863 NZ LYS A 433 3633 3611 3280 282 34 110 N ATOM 864 N TRP A 434 35.224 0.707 -12.721 1.00 9.68 N ANISOU 864 N TRP A 434 1283 1209 1186 62 32 66 N ATOM 865 CA TRP A 434 35.100 -0.084 -13.941 1.00 9.56 C ANISOU 865 CA TRP A 434 1248 1164 1217 75 35 35 C ATOM 866 C TRP A 434 36.075 0.448 -14.965 1.00 9.77 C ANISOU 866 C TRP A 434 1374 1104 1234 53 67 57 C ATOM 867 O TRP A 434 36.197 1.660 -15.111 1.00 10.85 O ANISOU 867 O TRP A 434 1621 1068 1432 -15 244 -51 O ATOM 868 CB TRP A 434 33.671 -0.028 -14.481 1.00 9.71 C ANISOU 868 CB TRP A 434 1274 1178 1236 5 5 -60 C ATOM 869 CG TRP A 434 32.737 -0.851 -13.685 1.00 9.69 C ANISOU 869 CG TRP A 434 1336 1179 1166 74 34 -5 C ATOM 870 CD1 TRP A 434 31.852 -0.415 -12.749 1.00 10.00 C ANISOU 870 CD1 TRP A 434 1351 1242 1203 94 49 -4 C ATOM 871 CD2 TRP A 434 32.599 -2.277 -13.733 1.00 9.40 C ANISOU 871 CD2 TRP A 434 1287 1179 1104 60 25 -123 C ATOM 872 NE1 TRP A 434 31.162 -1.477 -12.216 1.00 9.55 N ANISOU 872 NE1 TRP A 434 1272 1215 1138 86 -11 -45 N ATOM 873 CE2 TRP A 434 31.598 -2.631 -12.803 1.00 9.31 C ANISOU 873 CE2 TRP A 434 1321 1191 1026 56 -7 -48 C ATOM 874 CE3 TRP A 434 33.216 -3.289 -14.482 1.00 9.08 C ANISOU 874 CE3 TRP A 434 1230 1193 1024 127 22 -55 C ATOM 875 CZ2 TRP A 434 31.193 -3.956 -12.602 1.00 9.08 C ANISOU 875 CZ2 TRP A 434 1301 1185 962 13 25 -187 C ATOM 876 CZ3 TRP A 434 32.810 -4.602 -14.289 1.00 6.91 C ANISOU 876 CZ3 TRP A 434 960 927 737 377 97 -420 C ATOM 877 CH2 TRP A 434 31.828 -4.928 -13.349 1.00 8.68 C ANISOU 877 CH2 TRP A 434 1117 1095 1082 72 17 -85 C ATOM 878 N ILE A 435 36.796 -0.459 -15.629 1.00 9.44 N ANISOU 878 N ILE A 435 1242 1130 1212 41 21 45 N ATOM 879 CA ILE A 435 37.732 -0.112 -16.713 1.00 9.48 C ANISOU 879 CA ILE A 435 1246 1197 1159 -13 -25 13 C ATOM 880 C ILE A 435 37.030 -0.437 -18.029 1.00 8.58 C ANISOU 880 C ILE A 435 1191 983 1085 0 27 57 C ATOM 881 O ILE A 435 36.932 0.413 -18.916 1.00 8.04 O ANISOU 881 O ILE A 435 1202 841 1011 -174 -20 -10 O ATOM 882 CB ILE A 435 39.065 -0.882 -16.551 1.00 10.14 C ANISOU 882 CB ILE A 435 1203 1266 1383 -33 42 4 C ATOM 883 CG1 ILE A 435 39.724 -0.490 -15.220 1.00 10.69 C ANISOU 883 CG1 ILE A 435 1240 1511 1311 -47 27 144 C ATOM 884 CG2 ILE A 435 40.008 -0.599 -17.711 1.00 10.26 C ANISOU 884 CG2 ILE A 435 1320 1313 1263 44 9 41 C ATOM 885 CD1 ILE A 435 40.543 -1.608 -14.632 1.00 12.22 C ANISOU 885 CD1 ILE A 435 1490 1563 1589 121 54 78 C ATOM 886 N LYS A 436 36.522 -1.661 -18.131 1.00 8.02 N ANISOU 886 N LYS A 436 1049 986 1009 15 18 53 N ATOM 887 CA LYS A 436 35.638 -2.059 -19.218 1.00 8.10 C ANISOU 887 CA LYS A 436 1067 969 1039 -2 1 40 C ATOM 888 C LYS A 436 34.453 -2.867 -18.695 1.00 7.86 C ANISOU 888 C LYS A 436 1071 961 954 -15 -43 33 C ATOM 889 O LYS A 436 34.572 -3.609 -17.720 1.00 7.25 O ANISOU 889 O LYS A 436 800 1082 871 -116 -216 21 O ATOM 890 CB LYS A 436 36.387 -2.897 -20.252 1.00 8.36 C ANISOU 890 CB LYS A 436 1132 985 1057 -42 26 5 C ATOM 891 CG LYS A 436 37.576 -2.222 -20.908 1.00 8.54 C ANISOU 891 CG LYS A 436 1031 1114 1100 -9 13 -11 C ATOM 892 CD LYS A 436 37.189 -1.042 -21.772 1.00 8.60 C ANISOU 892 CD LYS A 436 1086 1090 1091 -84 4 14 C ATOM 893 CE LYS A 436 38.186 -0.814 -22.902 1.00 8.94 C ANISOU 893 CE LYS A 436 1090 1208 1098 -19 22 -8 C ATOM 894 NZ LYS A 436 39.586 -0.543 -22.480 1.00 8.92 N ANISOU 894 NZ LYS A 436 1137 1140 1109 -135 7 73 N ATOM 895 N THR A 437 33.319 -2.713 -19.375 1.00 7.84 N ANISOU 895 N THR A 437 1096 957 925 114 -33 -1 N ATOM 896 CA THR A 437 32.151 -3.538 -19.195 1.00 8.65 C ANISOU 896 CA THR A 437 1177 1043 1065 54 -3 9 C ATOM 897 C THR A 437 31.769 -4.165 -20.527 1.00 8.99 C ANISOU 897 C THR A 437 1343 974 1098 13 -5 9 C ATOM 898 O THR A 437 31.972 -3.575 -21.592 1.00 8.44 O ANISOU 898 O THR A 437 1418 692 1094 67 26 -43 O ATOM 899 CB THR A 437 30.966 -2.694 -18.673 1.00 9.32 C ANISOU 899 CB THR A 437 1250 1100 1191 116 -22 -41 C ATOM 900 OG1 THR A 437 30.648 -1.669 -19.624 1.00 10.31 O ANISOU 900 OG1 THR A 437 1596 1109 1211 174 -268 -110 O ATOM 901 CG2 THR A 437 31.341 -2.059 -17.368 1.00 9.20 C ANISOU 901 CG2 THR A 437 1174 1200 1121 92 24 -19 C ATOM 902 N CYS A 438 31.226 -5.376 -20.478 1.00 9.50 N ANISOU 902 N CYS A 438 1376 1032 1200 -55 -14 51 N ATOM 903 CA CYS A 438 30.898 -6.099 -21.707 1.00 9.65 C ANISOU 903 CA CYS A 438 1405 1035 1225 -34 -12 26 C ATOM 904 C CYS A 438 29.990 -7.269 -21.404 1.00 9.66 C ANISOU 904 C CYS A 438 1358 1041 1270 -33 -27 43 C ATOM 905 O CYS A 438 29.634 -7.498 -20.261 1.00 8.67 O ANISOU 905 O CYS A 438 1370 647 1276 -62 5 -9 O ATOM 906 CB CYS A 438 32.182 -6.587 -22.389 1.00 9.82 C ANISOU 906 CB CYS A 438 1384 1113 1234 -45 -6 14 C ATOM 907 SG CYS A 438 33.257 -7.587 -21.347 1.00 10.39 S ANISOU 907 SG CYS A 438 1517 1158 1270 -44 23 171 S ATOM 908 N ASN A 439 29.525 -7.936 -22.431 1.00 10.21 N ANISOU 908 N ASN A 439 1476 1150 1252 49 -49 10 N ATOM 909 CA ASN A 439 28.915 -9.250 -22.336 1.00 10.80 C ANISOU 909 CA ASN A 439 1568 1164 1370 20 -18 -21 C ATOM 910 C ASN A 439 29.475 -10.018 -23.523 1.00 9.13 C ANISOU 910 C ASN A 439 1142 1041 1283 117 -122 105 C ATOM 911 O ASN A 439 28.882 -10.052 -24.598 1.00 8.22 O ANISOU 911 O ASN A 439 1002 716 1402 260 -219 101 O ATOM 912 CB ASN A 439 27.377 -9.166 -22.356 1.00 13.37 C ANISOU 912 CB ASN A 439 1630 1610 1839 21 -109 10 C ATOM 913 CG ASN A 439 26.708 -10.526 -22.159 1.00 15.99 C ANISOU 913 CG ASN A 439 2213 1712 2148 -132 -103 165 C ATOM 914 OD1 ASN A 439 27.182 -11.387 -21.393 1.00 19.19 O ANISOU 914 OD1 ASN A 439 2605 2236 2450 498 -525 39 O ATOM 915 N LEU A 440 30.644 -10.623 -23.313 1.00 7.91 N ANISOU 915 N LEU A 440 1013 933 1059 23 0 108 N ATOM 916 CA LEU A 440 31.504 -11.045 -24.407 1.00 7.71 C ANISOU 916 CA LEU A 440 938 968 1022 52 -44 80 C ATOM 917 C LEU A 440 31.784 -12.526 -24.336 1.00 7.73 C ANISOU 917 C LEU A 440 934 978 1025 48 18 56 C ATOM 918 O LEU A 440 32.229 -13.011 -23.303 1.00 7.47 O ANISOU 918 O LEU A 440 986 794 1057 174 63 52 O ATOM 919 CB LEU A 440 32.830 -10.282 -24.314 1.00 7.74 C ANISOU 919 CB LEU A 440 972 987 980 18 21 28 C ATOM 920 CG LEU A 440 34.020 -10.801 -25.146 1.00 7.57 C ANISOU 920 CG LEU A 440 928 963 982 13 0 18 C ATOM 921 CD1 LEU A 440 33.775 -10.521 -26.615 1.00 7.50 C ANISOU 921 CD1 LEU A 440 916 956 977 23 -8 -13 C ATOM 922 CD2 LEU A 440 35.316 -10.148 -24.697 1.00 7.75 C ANISOU 922 CD2 LEU A 440 974 962 1008 8 -35 -8 C ATOM 923 N PHE A 441 31.560 -13.234 -25.441 1.00 8.24 N ANISOU 923 N PHE A 441 1016 1042 1070 3 -14 40 N ATOM 924 CA PHE A 441 32.068 -14.571 -25.583 1.00 8.43 C ANISOU 924 CA PHE A 441 1044 1055 1102 3 5 -11 C ATOM 925 C PHE A 441 33.341 -14.563 -26.403 1.00 8.61 C ANISOU 925 C PHE A 441 1059 1098 1113 -16 10 -22 C ATOM 926 O PHE A 441 33.358 -14.079 -27.544 1.00 8.66 O ANISOU 926 O PHE A 441 1034 1113 1141 118 12 4 O ATOM 927 CB PHE A 441 31.076 -15.532 -26.214 1.00 8.57 C ANISOU 927 CB PHE A 441 1126 1111 1017 -4 13 -80 C ATOM 928 CG PHE A 441 31.644 -16.903 -26.356 1.00 8.78 C ANISOU 928 CG PHE A 441 1113 1113 1108 22 6 -11 C ATOM 929 CD1 PHE A 441 31.922 -17.678 -25.216 1.00 8.82 C ANISOU 929 CD1 PHE A 441 1122 1140 1089 31 -15 -39 C ATOM 930 CD2 PHE A 441 31.981 -17.405 -27.608 1.00 8.67 C ANISOU 930 CD2 PHE A 441 1112 1085 1097 -12 -5 -12 C ATOM 931 CE1 PHE A 441 32.477 -18.940 -25.343 1.00 8.59 C ANISOU 931 CE1 PHE A 441 1036 1130 1094 14 -47 33 C ATOM 932 CE2 PHE A 441 32.557 -18.662 -27.729 1.00 8.54 C ANISOU 932 CE2 PHE A 441 1045 1076 1123 -42 -32 -61 C ATOM 933 CZ PHE A 441 32.789 -19.435 -26.601 1.00 8.42 C ANISOU 933 CZ PHE A 441 975 1077 1146 -3 -75 -54 C ATOM 934 N SER A 442 34.397 -15.099 -25.790 1.00 8.42 N ANISOU 934 N SER A 442 1034 1066 1097 -57 1 -7 N ATOM 935 CA SER A 442 35.692 -15.276 -26.418 1.00 8.76 C ANISOU 935 CA SER A 442 1046 1161 1122 -24 15 -5 C ATOM 936 C SER A 442 36.143 -16.662 -26.059 1.00 8.65 C ANISOU 936 C SER A 442 960 1185 1140 -23 7 9 C ATOM 937 O SER A 442 36.214 -17.001 -24.855 1.00 8.76 O ANISOU 937 O SER A 442 809 1430 1088 -24 43 -41 O ATOM 938 CB SER A 442 36.708 -14.273 -25.876 1.00 8.79 C ANISOU 938 CB SER A 442 990 1163 1184 -15 39 6 C ATOM 939 OG SER A 442 38.031 -14.748 -26.072 1.00 8.95 O ANISOU 939 OG SER A 442 951 1195 1253 27 -96 141 O ATOM 940 N ALA A 443 36.447 -17.466 -27.076 1.00 8.34 N ANISOU 940 N ALA A 443 964 1121 1081 -85 16 42 N ATOM 941 CA ALA A 443 36.857 -18.853 -26.833 1.00 8.65 C ANISOU 941 CA ALA A 443 1032 1155 1100 -21 -41 36 C ATOM 942 C ALA A 443 38.191 -18.907 -26.085 1.00 8.78 C ANISOU 942 C ALA A 443 1022 1153 1159 -136 -69 16 C ATOM 943 O ALA A 443 38.394 -19.801 -25.272 1.00 8.13 O ANISOU 943 O ALA A 443 828 1073 1185 -339 -214 -9 O ATOM 944 CB ALA A 443 36.923 -19.653 -28.121 1.00 8.63 C ANISOU 944 CB ALA A 443 1069 1101 1108 -12 -12 39 C ATOM 945 N GLU A 444 39.082 -17.940 -26.320 1.00 8.83 N ANISOU 945 N GLU A 444 1081 1133 1141 -126 -6 48 N ATOM 946 CA GLU A 444 40.311 -17.868 -25.522 1.00 9.02 C ANISOU 946 CA GLU A 444 1123 1141 1163 -36 -51 54 C ATOM 947 C GLU A 444 39.996 -17.528 -24.076 1.00 8.93 C ANISOU 947 C GLU A 444 1059 1145 1185 -6 -23 15 C ATOM 948 O GLU A 444 40.568 -18.135 -23.180 1.00 9.11 O ANISOU 948 O GLU A 444 1036 1197 1228 83 10 28 O ATOM 949 CB GLU A 444 41.334 -16.873 -26.073 1.00 9.90 C ANISOU 949 CB GLU A 444 1173 1302 1286 -65 42 91 C ATOM 950 CG GLU A 444 42.630 -16.912 -25.270 1.00 10.57 C ANISOU 950 CG GLU A 444 1334 1416 1266 -17 -81 99 C ATOM 951 CD GLU A 444 43.797 -16.210 -25.910 1.00 11.54 C ANISOU 951 CD GLU A 444 1363 1560 1461 -71 -106 161 C ATOM 952 OE1 GLU A 444 43.709 -15.748 -27.077 1.00 12.81 O ANISOU 952 OE1 GLU A 444 1627 1658 1580 -189 -188 328 O ATOM 953 OE2 GLU A 444 44.833 -16.099 -25.213 1.00 11.96 O ANISOU 953 OE2 GLU A 444 1380 1606 1558 347 -231 181 O ATOM 954 N ILE A 445 39.097 -16.569 -23.831 1.00 9.00 N ANISOU 954 N ILE A 445 1132 1185 1102 27 -44 -17 N ATOM 955 CA ILE A 445 38.702 -16.268 -22.437 1.00 8.68 C ANISOU 955 CA ILE A 445 1053 1084 1158 -26 34 -51 C ATOM 956 C ILE A 445 38.139 -17.520 -21.746 1.00 8.14 C ANISOU 956 C ILE A 445 1096 940 1054 105 -29 -56 C ATOM 957 O ILE A 445 38.550 -17.849 -20.630 1.00 7.59 O ANISOU 957 O ILE A 445 1060 766 1055 195 -12 -98 O ATOM 958 CB ILE A 445 37.724 -15.071 -22.325 1.00 8.82 C ANISOU 958 CB ILE A 445 1087 1123 1139 2 -2 -50 C ATOM 959 CG1 ILE A 445 38.459 -13.777 -22.725 1.00 9.32 C ANISOU 959 CG1 ILE A 445 1237 1108 1193 -8 15 -43 C ATOM 960 CG2 ILE A 445 37.174 -14.969 -20.901 1.00 8.64 C ANISOU 960 CG2 ILE A 445 1037 1108 1136 5 -14 -51 C ATOM 961 CD1 ILE A 445 37.620 -12.522 -22.708 1.00 9.82 C ANISOU 961 CD1 ILE A 445 1170 1284 1274 77 24 -8 C ATOM 962 N SER A 446 37.181 -18.172 -22.405 1.00 7.80 N ANISOU 962 N SER A 446 1107 883 974 41 33 -36 N ATOM 963 CA SER A 446 36.606 -19.438 -21.934 1.00 8.12 C ANISOU 963 CA SER A 446 1142 951 990 -15 -10 2 C ATOM 964 C SER A 446 37.677 -20.479 -21.606 1.00 8.11 C ANISOU 964 C SER A 446 1093 922 1065 -32 -41 -63 C ATOM 965 O SER A 446 37.595 -21.132 -20.567 1.00 8.46 O ANISOU 965 O SER A 446 1073 992 1148 87 -85 30 O ATOM 966 CB SER A 446 35.612 -20.022 -22.936 1.00 8.36 C ANISOU 966 CB SER A 446 1111 1028 1035 -63 -7 11 C ATOM 967 OG SER A 446 35.044 -21.240 -22.431 1.00 8.77 O ANISOU 967 OG SER A 446 1235 1041 1055 -163 49 -100 O ATOM 968 N GLU A 447 38.675 -20.624 -22.469 1.00 8.29 N ANISOU 968 N GLU A 447 1116 995 1036 -97 -34 1 N ATOM 969 CA GLU A 447 39.740 -21.618 -22.248 1.00 8.90 C ANISOU 969 CA GLU A 447 1119 1128 1132 -60 -55 54 C ATOM 970 C GLU A 447 40.622 -21.221 -21.069 1.00 8.30 C ANISOU 970 C GLU A 447 1001 1061 1091 -85 19 72 C ATOM 971 O GLU A 447 40.995 -22.063 -20.279 1.00 8.34 O ANISOU 971 O GLU A 447 1020 1016 1130 -242 42 151 O ATOM 972 CB GLU A 447 40.586 -21.830 -23.498 1.00 10.06 C ANISOU 972 CB GLU A 447 1249 1361 1212 -33 31 31 C ATOM 973 CG GLU A 447 41.585 -22.947 -23.330 1.00 11.73 C ANISOU 973 CG GLU A 447 1407 1603 1446 129 5 106 C ATOM 974 CD GLU A 447 42.327 -23.350 -24.591 1.00 13.79 C ANISOU 974 CD GLU A 447 1604 2006 1626 271 216 144 C ATOM 975 OE1 GLU A 447 42.047 -22.839 -25.703 1.00 13.88 O ANISOU 975 OE1 GLU A 447 1186 2340 1745 456 107 199 O ATOM 976 OE2 GLU A 447 43.214 -24.209 -24.455 1.00 16.12 O ANISOU 976 OE2 GLU A 447 1865 2479 1780 623 243 162 O ATOM 977 N ILE A 448 40.955 -19.941 -20.956 1.00 8.14 N ANISOU 977 N ILE A 448 1016 1099 977 -160 12 23 N ATOM 978 CA ILE A 448 41.713 -19.460 -19.792 1.00 8.03 C ANISOU 978 CA ILE A 448 964 1076 1008 -105 -9 36 C ATOM 979 C ILE A 448 40.967 -19.761 -18.499 1.00 7.93 C ANISOU 979 C ILE A 448 955 1081 974 -57 -33 50 C ATOM 980 O ILE A 448 41.548 -20.316 -17.569 1.00 8.21 O ANISOU 980 O ILE A 448 837 1246 1037 -78 -34 130 O ATOM 981 CB ILE A 448 42.032 -17.948 -19.890 1.00 7.77 C ANISOU 981 CB ILE A 448 971 1016 962 -21 0 6 C ATOM 982 CG1 ILE A 448 43.100 -17.715 -20.967 1.00 7.65 C ANISOU 982 CG1 ILE A 448 959 974 972 -62 -9 8 C ATOM 983 CG2 ILE A 448 42.527 -17.391 -18.549 1.00 7.70 C ANISOU 983 CG2 ILE A 448 938 1020 965 -54 -12 31 C ATOM 984 CD1 ILE A 448 43.245 -16.260 -21.382 1.00 7.47 C ANISOU 984 CD1 ILE A 448 937 971 930 -28 -28 16 C ATOM 985 N VAL A 449 39.678 -19.423 -18.464 1.00 7.72 N ANISOU 985 N VAL A 449 977 1021 934 1 -30 -23 N ATOM 986 CA VAL A 449 38.877 -19.579 -17.257 1.00 7.68 C ANISOU 986 CA VAL A 449 948 985 985 -40 -16 -13 C ATOM 987 C VAL A 449 38.716 -21.065 -16.911 1.00 7.53 C ANISOU 987 C VAL A 449 935 964 961 65 -53 -15 C ATOM 988 O VAL A 449 38.817 -21.434 -15.747 1.00 6.32 O ANISOU 988 O VAL A 449 774 722 902 90 -147 -129 O ATOM 989 CB VAL A 449 37.526 -18.816 -17.373 1.00 7.81 C ANISOU 989 CB VAL A 449 995 966 1004 -9 13 -37 C ATOM 990 CG1 VAL A 449 36.583 -19.139 -16.218 1.00 7.89 C ANISOU 990 CG1 VAL A 449 1021 987 989 28 46 -102 C ATOM 991 CG2 VAL A 449 37.775 -17.301 -17.452 1.00 8.12 C ANISOU 991 CG2 VAL A 449 1037 975 1070 -7 41 -74 C ATOM 992 N SER A 450 38.489 -21.900 -17.934 1.00 8.47 N ANISOU 992 N SER A 450 1131 1049 1038 18 -96 -78 N ATOM 993 CA SER A 450 38.358 -23.368 -17.782 1.00 9.07 C ANISOU 993 CA SER A 450 1243 1063 1138 31 -69 -23 C ATOM 994 C SER A 450 39.568 -24.071 -17.183 1.00 9.24 C ANISOU 994 C SER A 450 1268 1188 1054 20 -140 -65 C ATOM 995 O SER A 450 39.425 -25.177 -16.665 1.00 9.53 O ANISOU 995 O SER A 450 1373 1177 1068 44 -290 -45 O ATOM 996 CB SER A 450 38.133 -24.018 -19.151 1.00 9.75 C ANISOU 996 CB SER A 450 1334 1140 1228 -63 -124 -89 C ATOM 997 OG SER A 450 36.917 -23.599 -19.702 1.00 11.60 O ANISOU 997 OG SER A 450 1505 1336 1567 -90 -309 55 O ATOM 998 N HIS A 451 40.751 -23.480 -17.336 1.00 9.44 N ANISOU 998 N HIS A 451 1343 1190 1051 -41 -26 -80 N ATOM 999 CA HIS A 451 42.022 -24.087 -16.881 1.00 10.32 C ANISOU 999 CA HIS A 451 1436 1193 1290 55 -38 -42 C ATOM 1000 C HIS A 451 42.743 -23.262 -15.815 1.00 8.81 C ANISOU 1000 C HIS A 451 1214 1019 1111 24 83 104 C ATOM 1001 O HIS A 451 43.905 -23.522 -15.521 1.00 7.62 O ANISOU 1001 O HIS A 451 1247 567 1079 123 145 69 O ATOM 1002 CB HIS A 451 42.960 -24.282 -18.093 1.00 12.69 C ANISOU 1002 CB HIS A 451 1696 1607 1518 41 183 7 C ATOM 1003 CG HIS A 451 42.360 -25.113 -19.188 1.00 15.82 C ANISOU 1003 CG HIS A 451 2197 1874 1939 -135 88 -256 C ATOM 1004 ND1 HIS A 451 42.635 -24.909 -20.522 1.00 18.27 N ANISOU 1004 ND1 HIS A 451 2832 2071 2037 -80 -34 -24 N ATOM 1005 CD2 HIS A 451 41.496 -26.152 -19.140 1.00 16.62 C ANISOU 1005 CD2 HIS A 451 2100 2036 2177 -161 291 -214 C ATOM 1006 CE1 HIS A 451 41.963 -25.786 -21.247 1.00 18.05 C ANISOU 1006 CE1 HIS A 451 2576 2023 2260 -94 14 3 C ATOM 1007 NE2 HIS A 451 41.253 -26.541 -20.433 1.00 16.50 N ANISOU 1007 NE2 HIS A 451 2176 1903 2188 20 155 -172 N ATOM 1008 N MET A 452 42.055 -22.281 -15.226 1.00 8.29 N ANISOU 1008 N MET A 452 1100 982 1066 -45 98 117 N ATOM 1009 CA MET A 452 42.705 -21.321 -14.327 1.00 9.03 C ANISOU 1009 CA MET A 452 1117 1151 1159 -34 58 21 C ATOM 1010 C MET A 452 43.182 -21.934 -13.003 1.00 9.25 C ANISOU 1010 C MET A 452 1181 1201 1131 -76 85 40 C ATOM 1011 O MET A 452 44.183 -21.484 -12.436 1.00 9.09 O ANISOU 1011 O MET A 452 979 1304 1170 -182 247 134 O ATOM 1012 CB MET A 452 41.784 -20.136 -14.068 1.00 9.32 C ANISOU 1012 CB MET A 452 1258 1066 1216 -26 18 38 C ATOM 1013 CG MET A 452 42.435 -18.961 -13.358 1.00 9.34 C ANISOU 1013 CG MET A 452 1230 1084 1232 -17 -4 41 C ATOM 1014 SD MET A 452 41.197 -17.671 -13.168 1.00 8.78 S ANISOU 1014 SD MET A 452 1276 849 1211 -90 21 132 S ATOM 1015 CE MET A 452 41.282 -16.987 -14.821 1.00 9.41 C ANISOU 1015 CE MET A 452 1357 1115 1103 -81 -20 54 C ATOM 1016 N ASP A 453 42.484 -22.956 -12.516 1.00 9.78 N ANISOU 1016 N ASP A 453 1151 1284 1281 -145 150 7 N ATOM 1017 CA ASP A 453 42.900 -23.664 -11.296 1.00 10.90 C ANISOU 1017 CA ASP A 453 1349 1335 1456 -36 3 75 C ATOM 1018 C ASP A 453 43.835 -24.827 -11.647 1.00 12.65 C ANISOU 1018 C ASP A 453 1593 1434 1779 89 119 138 C ATOM 1019 O ASP A 453 43.402 -25.984 -11.705 1.00 13.10 O ANISOU 1019 O ASP A 453 1649 1369 1958 137 264 365 O ATOM 1020 CB ASP A 453 41.669 -24.166 -10.518 1.00 10.79 C ANISOU 1020 CB ASP A 453 1488 1278 1333 -24 55 76 C ATOM 1021 CG ASP A 453 42.035 -24.854 -9.209 1.00 11.26 C ANISOU 1021 CG ASP A 453 1553 1257 1468 -39 -18 161 C ATOM 1022 OD1 ASP A 453 43.148 -24.622 -8.692 1.00 11.74 O ANISOU 1022 OD1 ASP A 453 1736 1238 1484 -90 -199 296 O ATOM 1023 OD2 ASP A 453 41.196 -25.613 -8.687 1.00 10.90 O ANISOU 1023 OD2 ASP A 453 1690 1105 1346 -216 -155 19 O ATOM 1024 N HIS A 454 45.106 -24.510 -11.893 1.00 14.02 N ANISOU 1024 N HIS A 454 1663 1677 1987 22 186 440 N ATOM 1025 CA HIS A 454 46.114 -25.507 -12.243 1.00 16.64 C ANISOU 1025 CA HIS A 454 1897 2039 2385 152 248 148 C ATOM 1026 C HIS A 454 45.549 -26.529 -13.240 1.00 15.88 C ANISOU 1026 C HIS A 454 1836 1858 2338 142 293 257 C ATOM 1027 O HIS A 454 45.639 -27.731 -13.023 1.00 17.55 O ANISOU 1027 O HIS A 454 1891 1955 2821 320 354 582 O ATOM 1028 CB HIS A 454 46.647 -26.197 -10.964 1.00 19.38 C ANISOU 1028 CB HIS A 454 2340 2429 2594 68 42 321 C ATOM 1029 CG HIS A 454 47.327 -25.265 -9.995 1.00 23.90 C ANISOU 1029 CG HIS A 454 2858 3119 3101 -297 118 -169 C ATOM 1030 ND1 HIS A 454 48.503 -24.606 -10.292 1.00 26.83 N ANISOU 1030 ND1 HIS A 454 3128 3462 3604 -512 405 -106 N ATOM 1031 CD2 HIS A 454 47.015 -24.914 -8.721 1.00 25.76 C ANISOU 1031 CD2 HIS A 454 3130 3470 3187 -174 461 -59 C ATOM 1032 CE1 HIS A 454 48.873 -23.873 -9.254 1.00 28.82 C ANISOU 1032 CE1 HIS A 454 3418 3971 3558 -413 247 -135 C ATOM 1033 NE2 HIS A 454 47.987 -24.042 -8.287 1.00 28.65 N ANISOU 1033 NE2 HIS A 454 3489 3982 3412 -256 251 -224 N ATOM 1034 N GLY A 455 44.918 -26.023 -14.301 1.00 14.68 N ANISOU 1034 N GLY A 455 1749 1742 2087 6 449 197 N ATOM 1035 CA GLY A 455 44.351 -26.842 -15.365 1.00 16.19 C ANISOU 1035 CA GLY A 455 1970 1992 2189 -27 244 161 C ATOM 1036 C GLY A 455 42.877 -27.195 -15.272 1.00 14.42 C ANISOU 1036 C GLY A 455 1892 1624 1962 71 27 9 C ATOM 1037 O GLY A 455 42.325 -27.734 -16.222 1.00 14.99 O ANISOU 1037 O GLY A 455 2456 1179 2059 234 -90 -133 O ATOM 1038 N SER A 456 42.245 -26.900 -14.138 1.00 14.28 N ANISOU 1038 N SER A 456 1796 1582 2045 -49 87 -7 N ATOM 1039 CA SER A 456 40.806 -27.133 -13.926 1.00 14.34 C ANISOU 1039 CA SER A 456 1713 1631 2103 69 0 -92 C ATOM 1040 C SER A 456 40.045 -25.811 -13.871 1.00 12.84 C ANISOU 1040 C SER A 456 1526 1535 1815 -21 -38 -20 C ATOM 1041 O SER A 456 40.657 -24.731 -13.867 1.00 11.59 O ANISOU 1041 O SER A 456 1025 1384 1993 250 7 -19 O ATOM 1042 CB SER A 456 40.597 -27.928 -12.636 1.00 16.03 C ANISOU 1042 CB SER A 456 1945 1921 2223 -21 2 65 C ATOM 1043 OG SER A 456 41.089 -29.251 -12.792 1.00 19.41 O ANISOU 1043 OG SER A 456 2554 2056 2762 98 243 -165 O ATOM 1044 N GLU A 457 38.718 -25.891 -13.837 1.00 12.05 N ANISOU 1044 N GLU A 457 1535 1401 1641 -86 -60 -108 N ATOM 1045 CA GLU A 457 37.868 -24.692 -13.873 1.00 12.61 C ANISOU 1045 CA GLU A 457 1717 1456 1617 -10 -19 -132 C ATOM 1046 C GLU A 457 38.160 -23.730 -12.729 1.00 10.21 C ANISOU 1046 C GLU A 457 1197 1231 1452 -52 -66 55 C ATOM 1047 O GLU A 457 38.430 -24.159 -11.618 1.00 7.62 O ANISOU 1047 O GLU A 457 867 589 1439 -145 -83 -50 O ATOM 1048 CB GLU A 457 36.374 -25.047 -13.864 1.00 16.23 C ANISOU 1048 CB GLU A 457 1797 1972 2394 -125 -12 -218 C ATOM 1049 CG GLU A 457 35.857 -25.687 -12.581 1.00 19.10 C ANISOU 1049 CG GLU A 457 2447 2380 2428 -95 160 -170 C ATOM 1050 CD GLU A 457 34.355 -25.899 -12.607 1.00 25.49 C ANISOU 1050 CD GLU A 457 2566 3383 3736 -393 260 -536 C ATOM 1051 OE1 GLU A 457 33.604 -24.918 -12.414 1.00 29.79 O ANISOU 1051 OE1 GLU A 457 2969 3719 4630 -28 354 -333 O ATOM 1052 OE2 GLU A 457 33.921 -27.048 -12.814 1.00 30.84 O ANISOU 1052 OE2 GLU A 457 3345 3590 4783 -640 397 -940 O ATOM 1053 N ALA A 458 38.059 -22.434 -13.012 1.00 9.55 N ANISOU 1053 N ALA A 458 1234 1200 1192 -76 -46 -17 N ATOM 1054 CA ALA A 458 38.284 -21.391 -12.007 1.00 8.98 C ANISOU 1054 CA ALA A 458 1158 1089 1162 -32 -8 29 C ATOM 1055 C ALA A 458 37.353 -21.566 -10.806 1.00 8.77 C ANISOU 1055 C ALA A 458 1141 1028 1163 3 -9 25 C ATOM 1056 O ALA A 458 36.183 -21.929 -10.955 1.00 9.82 O ANISOU 1056 O ALA A 458 1123 1233 1372 23 -93 80 O ATOM 1057 CB ALA A 458 38.082 -20.016 -12.610 1.00 8.57 C ANISOU 1057 CB ALA A 458 1111 1094 1048 -61 -12 25 C ATOM 1058 N ARG A 459 37.889 -21.325 -9.631 1.00 8.40 N ANISOU 1058 N ARG A 459 1093 971 1127 18 8 44 N ATOM 1059 CA ARG A 459 37.127 -21.311 -8.386 1.00 9.03 C ANISOU 1059 CA ARG A 459 1136 1147 1146 -1 28 27 C ATOM 1060 C ARG A 459 36.813 -19.833 -8.086 1.00 9.44 C ANISOU 1060 C ARG A 459 1223 1157 1205 -26 72 -41 C ATOM 1061 O ARG A 459 37.634 -18.983 -8.236 1.00 9.53 O ANISOU 1061 O ARG A 459 1260 1239 1121 -81 100 -102 O ATOM 1062 CB ARG A 459 37.904 -21.916 -7.230 1.00 9.14 C ANISOU 1062 CB ARG A 459 1183 1170 1117 -54 5 60 C ATOM 1063 CG ARG A 459 38.247 -23.353 -7.489 1.00 9.89 C ANISOU 1063 CG ARG A 459 1294 1260 1204 48 -2 -44 C ATOM 1064 CD ARG A 459 38.677 -24.135 -6.245 1.00 10.46 C ANISOU 1064 CD ARG A 459 1357 1338 1278 35 -35 35 C ATOM 1065 NE ARG A 459 39.313 -25.389 -6.607 1.00 11.03 N ANISOU 1065 NE ARG A 459 1450 1379 1362 28 -19 -39 N ATOM 1066 CZ ARG A 459 38.941 -26.601 -6.185 1.00 11.26 C ANISOU 1066 CZ ARG A 459 1374 1487 1416 -5 -51 67 C ATOM 1067 NH1 ARG A 459 37.967 -26.778 -5.358 1.00 11.83 N ANISOU 1067 NH1 ARG A 459 1607 1546 1341 -89 30 113 N ATOM 1068 NH2 ARG A 459 39.548 -27.620 -6.631 1.00 11.89 N ANISOU 1068 NH2 ARG A 459 1514 1486 1515 -23 -62 -14 N ATOM 1069 N ASP A 460 35.614 -19.562 -7.616 1.00 9.67 N ANISOU 1069 N ASP A 460 1200 1185 1289 -77 77 -54 N ATOM 1070 CA ASP A 460 35.168 -18.197 -7.392 1.00 9.79 C ANISOU 1070 CA ASP A 460 1240 1235 1245 -5 59 -40 C ATOM 1071 C ASP A 460 36.088 -17.467 -6.411 1.00 9.28 C ANISOU 1071 C ASP A 460 1256 1088 1181 9 85 -5 C ATOM 1072 O ASP A 460 36.389 -17.967 -5.303 1.00 8.73 O ANISOU 1072 O ASP A 460 1297 954 1064 -34 212 -59 O ATOM 1073 CB ASP A 460 33.729 -18.189 -6.883 1.00 10.52 C ANISOU 1073 CB ASP A 460 1270 1371 1353 22 88 -32 C ATOM 1074 CG ASP A 460 33.140 -16.798 -6.792 1.00 10.90 C ANISOU 1074 CG ASP A 460 1285 1475 1379 159 89 31 C ATOM 1075 OD1 ASP A 460 33.540 -15.864 -7.541 1.00 10.75 O ANISOU 1075 OD1 ASP A 460 1096 1586 1402 95 48 73 O ATOM 1076 OD2 ASP A 460 32.263 -16.647 -5.938 1.00 11.85 O ANISOU 1076 OD2 ASP A 460 1360 1596 1545 104 261 241 O ATOM 1077 N GLY A 461 36.561 -16.305 -6.849 1.00 8.76 N ANISOU 1077 N GLY A 461 1145 1142 1040 -43 82 -12 N ATOM 1078 CA GLY A 461 37.386 -15.446 -6.014 1.00 8.80 C ANISOU 1078 CA GLY A 461 1142 1099 1100 -60 77 19 C ATOM 1079 C GLY A 461 38.855 -15.782 -5.999 1.00 7.79 C ANISOU 1079 C GLY A 461 1128 920 909 -90 29 59 C ATOM 1080 O GLY A 461 39.599 -15.132 -5.272 1.00 8.32 O ANISOU 1080 O GLY A 461 1246 914 998 -223 55 51 O ATOM 1081 N MET A 462 39.289 -16.795 -6.762 1.00 7.21 N ANISOU 1081 N MET A 462 967 953 818 -83 24 77 N ATOM 1082 CA MET A 462 40.696 -17.184 -6.757 1.00 7.28 C ANISOU 1082 CA MET A 462 978 896 892 -58 12 22 C ATOM 1083 C MET A 462 41.530 -16.115 -7.421 1.00 6.90 C ANISOU 1083 C MET A 462 880 850 889 -47 3 -31 C ATOM 1084 O MET A 462 41.081 -15.442 -8.334 1.00 6.37 O ANISOU 1084 O MET A 462 716 820 884 -169 18 -5 O ATOM 1085 CB MET A 462 40.926 -18.519 -7.469 1.00 7.39 C ANISOU 1085 CB MET A 462 926 919 960 -41 28 -8 C ATOM 1086 CG MET A 462 40.830 -18.458 -8.985 1.00 7.59 C ANISOU 1086 CG MET A 462 941 970 971 -41 -3 -55 C ATOM 1087 SD MET A 462 41.194 -20.024 -9.747 1.00 7.91 S ANISOU 1087 SD MET A 462 991 990 1022 -142 -22 -153 S ATOM 1088 CE MET A 462 42.975 -20.117 -9.526 1.00 8.48 C ANISOU 1088 CE MET A 462 1025 1106 1090 -28 -17 -41 C ATOM 1089 N GLU A 463 42.749 -15.960 -6.951 1.00 7.20 N ANISOU 1089 N GLU A 463 905 882 948 -33 -32 -22 N ATOM 1090 CA GLU A 463 43.704 -15.129 -7.639 1.00 7.52 C ANISOU 1090 CA GLU A 463 873 971 1010 -26 -7 9 C ATOM 1091 C GLU A 463 44.227 -15.920 -8.827 1.00 7.91 C ANISOU 1091 C GLU A 463 936 1013 1057 -16 -12 -37 C ATOM 1092 O GLU A 463 44.364 -17.128 -8.740 1.00 8.61 O ANISOU 1092 O GLU A 463 1004 1017 1250 -4 69 -53 O ATOM 1093 CB GLU A 463 44.866 -14.760 -6.713 1.00 7.55 C ANISOU 1093 CB GLU A 463 861 987 1017 -48 5 16 C ATOM 1094 CG GLU A 463 45.799 -13.747 -7.359 1.00 7.34 C ANISOU 1094 CG GLU A 463 796 972 1019 14 12 71 C ATOM 1095 CD GLU A 463 46.682 -13.020 -6.392 1.00 6.87 C ANISOU 1095 CD GLU A 463 697 932 979 -2 45 140 C ATOM 1096 OE1 GLU A 463 46.673 -13.341 -5.176 1.00 6.21 O ANISOU 1096 OE1 GLU A 463 450 890 1020 5 246 217 O ATOM 1097 OE2 GLU A 463 47.401 -12.100 -6.864 1.00 6.58 O ANISOU 1097 OE2 GLU A 463 565 1039 895 33 55 206 O ATOM 1098 N MET A 464 44.525 -15.225 -9.914 1.00 8.10 N ANISOU 1098 N MET A 464 952 1027 1097 -4 -26 2 N ATOM 1099 CA MET A 464 45.073 -15.821 -11.125 1.00 8.58 C ANISOU 1099 CA MET A 464 1086 1076 1096 37 3 19 C ATOM 1100 C MET A 464 46.487 -15.304 -11.276 1.00 8.82 C ANISOU 1100 C MET A 464 1111 1131 1107 29 53 7 C ATOM 1101 O MET A 464 46.914 -14.404 -10.549 1.00 9.04 O ANISOU 1101 O MET A 464 1051 1271 1113 -31 189 -108 O ATOM 1102 CB MET A 464 44.231 -15.449 -12.349 1.00 8.85 C ANISOU 1102 CB MET A 464 1167 1120 1074 23 16 65 C ATOM 1103 CG MET A 464 44.183 -13.966 -12.675 1.00 8.47 C ANISOU 1103 CG MET A 464 1081 1124 1012 55 -33 67 C ATOM 1104 SD MET A 464 43.002 -13.618 -13.979 1.00 8.36 S ANISOU 1104 SD MET A 464 1249 1003 921 213 0 170 S ATOM 1105 CE MET A 464 41.492 -13.527 -13.025 1.00 8.41 C ANISOU 1105 CE MET A 464 1111 1006 1078 122 -32 75 C ATOM 1106 N MET A 465 47.216 -15.857 -12.234 1.00 8.79 N ANISOU 1106 N MET A 465 1203 1073 1064 97 21 19 N ATOM 1107 CA MET A 465 48.574 -15.404 -12.487 1.00 9.12 C ANISOU 1107 CA MET A 465 1167 1141 1157 76 -50 45 C ATOM 1108 C MET A 465 48.572 -14.045 -13.184 1.00 8.54 C ANISOU 1108 C MET A 465 1037 1110 1098 71 -57 11 C ATOM 1109 O MET A 465 47.579 -13.686 -13.820 1.00 8.20 O ANISOU 1109 O MET A 465 1074 895 1146 111 -36 137 O ATOM 1110 CB MET A 465 49.308 -16.448 -13.318 1.00 10.12 C ANISOU 1110 CB MET A 465 1230 1264 1350 87 -27 -87 C ATOM 1111 CG MET A 465 49.490 -17.731 -12.536 1.00 10.86 C ANISOU 1111 CG MET A 465 1373 1292 1461 67 4 -42 C ATOM 1112 SD MET A 465 50.406 -19.006 -13.407 1.00 13.95 S ANISOU 1112 SD MET A 465 1650 1528 2120 394 -148 -316 S ATOM 1113 CE MET A 465 49.286 -19.325 -14.766 1.00 15.13 C ANISOU 1113 CE MET A 465 1861 1795 2092 80 -170 -153 C ATOM 1114 N TYR A 466 49.668 -13.293 -13.046 1.00 8.43 N ANISOU 1114 N TYR A 466 1049 1104 1049 48 -23 29 N ATOM 1115 CA TYR A 466 49.845 -12.019 -13.756 1.00 8.68 C ANISOU 1115 CA TYR A 466 1057 1072 1169 -9 10 8 C ATOM 1116 C TYR A 466 49.521 -12.133 -15.247 1.00 8.96 C ANISOU 1116 C TYR A 466 1068 1142 1192 -62 -22 10 C ATOM 1117 O TYR A 466 48.804 -11.293 -15.794 1.00 9.58 O ANISOU 1117 O TYR A 466 1326 1034 1280 -17 -110 -48 O ATOM 1118 CB TYR A 466 51.282 -11.453 -13.591 1.00 8.97 C ANISOU 1118 CB TYR A 466 1094 1141 1171 -48 -3 29 C ATOM 1119 CG TYR A 466 51.460 -10.171 -14.386 1.00 8.89 C ANISOU 1119 CG TYR A 466 1041 1142 1193 -116 -1 32 C ATOM 1120 CD1 TYR A 466 50.930 -8.958 -13.928 1.00 8.75 C ANISOU 1120 CD1 TYR A 466 929 1195 1198 -78 23 60 C ATOM 1121 CD2 TYR A 466 52.079 -10.190 -15.628 1.00 9.04 C ANISOU 1121 CD2 TYR A 466 1061 1169 1203 -88 10 6 C ATOM 1122 CE1 TYR A 466 51.060 -7.788 -14.673 1.00 8.93 C ANISOU 1122 CE1 TYR A 466 946 1177 1267 26 -9 78 C ATOM 1123 CE2 TYR A 466 52.195 -9.035 -16.390 1.00 9.58 C ANISOU 1123 CE2 TYR A 466 1137 1222 1279 -38 60 61 C ATOM 1124 CZ TYR A 466 51.696 -7.837 -15.910 1.00 8.84 C ANISOU 1124 CZ TYR A 466 926 1181 1251 -56 -30 114 C ATOM 1125 OH TYR A 466 51.824 -6.711 -16.687 1.00 8.74 O ANISOU 1125 OH TYR A 466 826 1059 1435 -215 13 68 O ATOM 1126 N ASP A 467 50.056 -13.158 -15.908 1.00 9.50 N ANISOU 1126 N ASP A 467 1205 1173 1231 -7 -27 -2 N ATOM 1127 CA ASP A 467 49.855 -13.311 -17.364 1.00 10.00 C ANISOU 1127 CA ASP A 467 1268 1304 1224 -7 7 45 C ATOM 1128 C ASP A 467 48.423 -13.684 -17.732 1.00 9.50 C ANISOU 1128 C ASP A 467 1214 1248 1147 32 49 83 C ATOM 1129 O ASP A 467 47.960 -13.327 -18.802 1.00 9.53 O ANISOU 1129 O ASP A 467 1200 1459 962 -85 178 66 O ATOM 1130 CB ASP A 467 50.839 -14.321 -17.973 1.00 10.87 C ANISOU 1130 CB ASP A 467 1300 1446 1382 52 49 -9 C ATOM 1131 CG ASP A 467 52.278 -13.793 -18.033 1.00 11.41 C ANISOU 1131 CG ASP A 467 1313 1484 1535 44 129 17 C ATOM 1132 OD1 ASP A 467 52.488 -12.567 -18.083 1.00 11.75 O ANISOU 1132 OD1 ASP A 467 1393 1533 1537 -42 214 168 O ATOM 1133 OD2 ASP A 467 53.210 -14.618 -18.034 1.00 11.60 O ANISOU 1133 OD2 ASP A 467 1011 1714 1680 0 80 -122 O ATOM 1134 N GLU A 468 47.716 -14.397 -16.859 1.00 9.41 N ANISOU 1134 N GLU A 468 1214 1192 1168 24 -9 118 N ATOM 1135 CA GLU A 468 46.298 -14.664 -17.095 1.00 9.13 C ANISOU 1135 CA GLU A 468 1193 1152 1122 25 3 69 C ATOM 1136 C GLU A 468 45.471 -13.372 -16.993 1.00 8.95 C ANISOU 1136 C GLU A 468 1204 1118 1078 -3 -54 75 C ATOM 1137 O GLU A 468 44.644 -13.092 -17.867 1.00 8.38 O ANISOU 1137 O GLU A 468 1066 1032 1084 -61 -45 30 O ATOM 1138 CB GLU A 468 45.776 -15.716 -16.134 1.00 9.30 C ANISOU 1138 CB GLU A 468 1194 1156 1184 -25 -15 69 C ATOM 1139 CG GLU A 468 46.367 -17.091 -16.384 1.00 9.61 C ANISOU 1139 CG GLU A 468 1280 1130 1241 -78 3 28 C ATOM 1140 CD GLU A 468 46.034 -18.073 -15.279 1.00 10.30 C ANISOU 1140 CD GLU A 468 1541 1096 1273 -197 -88 28 C ATOM 1141 OE1 GLU A 468 46.267 -17.743 -14.081 1.00 9.67 O ANISOU 1141 OE1 GLU A 468 1401 981 1293 -160 -14 -68 O ATOM 1142 OE2 GLU A 468 45.546 -19.171 -15.615 1.00 10.32 O ANISOU 1142 OE2 GLU A 468 1627 1082 1211 -194 -88 -15 O ATOM 1143 N GLY A 469 45.710 -12.584 -15.936 1.00 8.77 N ANISOU 1143 N GLY A 469 1210 987 1134 -37 -31 88 N ATOM 1144 CA GLY A 469 44.996 -11.328 -15.736 1.00 8.44 C ANISOU 1144 CA GLY A 469 1069 1047 1091 -46 -26 35 C ATOM 1145 C GLY A 469 45.284 -10.341 -16.843 1.00 8.44 C ANISOU 1145 C GLY A 469 1020 1045 1141 -42 -23 69 C ATOM 1146 O GLY A 469 44.379 -9.696 -17.355 1.00 7.76 O ANISOU 1146 O GLY A 469 869 992 1084 -156 24 92 O ATOM 1147 N SER A 470 46.549 -10.245 -17.238 1.00 8.57 N ANISOU 1147 N SER A 470 1036 1089 1131 -31 -13 54 N ATOM 1148 CA SER A 470 46.940 -9.353 -18.335 1.00 8.49 C ANISOU 1148 CA SER A 470 1013 1074 1136 -17 -76 80 C ATOM 1149 C SER A 470 46.333 -9.767 -19.657 1.00 8.45 C ANISOU 1149 C SER A 470 1064 1089 1054 8 3 52 C ATOM 1150 O SER A 470 45.800 -8.924 -20.377 1.00 8.29 O ANISOU 1150 O SER A 470 1017 1174 957 63 -40 -14 O ATOM 1151 CB SER A 470 48.456 -9.268 -18.440 1.00 8.99 C ANISOU 1151 CB SER A 470 1012 1141 1262 -30 -99 96 C ATOM 1152 OG SER A 470 48.921 -8.677 -17.245 1.00 9.64 O ANISOU 1152 OG SER A 470 919 1287 1457 -14 -379 124 O ATOM 1153 N ARG A 471 46.385 -11.060 -19.962 1.00 8.94 N ANISOU 1153 N ARG A 471 1195 1102 1097 15 -4 33 N ATOM 1154 CA ARG A 471 45.774 -11.569 -21.196 1.00 8.99 C ANISOU 1154 CA ARG A 471 1176 1113 1124 -2 -12 23 C ATOM 1155 C ARG A 471 44.244 -11.363 -21.251 1.00 8.37 C ANISOU 1155 C ARG A 471 1195 973 1012 50 -19 48 C ATOM 1156 O ARG A 471 43.690 -11.035 -22.308 1.00 7.79 O ANISOU 1156 O ARG A 471 1181 751 1024 195 92 192 O ATOM 1157 CB ARG A 471 46.131 -13.044 -21.413 1.00 9.36 C ANISOU 1157 CB ARG A 471 1210 1141 1204 -2 4 -28 C ATOM 1158 CG ARG A 471 45.626 -13.625 -22.719 1.00 9.85 C ANISOU 1158 CG ARG A 471 1304 1224 1211 8 -22 -44 C ATOM 1159 CD ARG A 471 46.170 -12.872 -23.916 1.00 10.68 C ANISOU 1159 CD ARG A 471 1385 1260 1411 -119 42 33 C ATOM 1160 NE ARG A 471 45.860 -13.526 -25.182 1.00 11.34 N ANISOU 1160 NE ARG A 471 1532 1353 1423 -148 -19 44 N ATOM 1161 CZ ARG A 471 46.122 -13.014 -26.385 1.00 12.52 C ANISOU 1161 CZ ARG A 471 1719 1563 1472 -169 105 41 C ATOM 1162 NH1 ARG A 471 46.718 -11.831 -26.518 1.00 12.50 N ANISOU 1162 NH1 ARG A 471 1744 1482 1524 -115 55 76 N ATOM 1163 NH2 ARG A 471 45.780 -13.696 -27.471 1.00 13.93 N ANISOU 1163 NH2 ARG A 471 2013 1682 1597 -184 33 -60 N ATOM 1164 N LEU A 472 43.559 -11.588 -20.133 1.00 7.87 N ANISOU 1164 N LEU A 472 1134 849 1008 61 -22 4 N ATOM 1165 CA LEU A 472 42.132 -11.356 -20.085 1.00 8.10 C ANISOU 1165 CA LEU A 472 1101 943 1030 -20 -10 34 C ATOM 1166 C LEU A 472 41.815 -9.874 -20.298 1.00 7.97 C ANISOU 1166 C LEU A 472 1047 965 1015 -3 -8 74 C ATOM 1167 O LEU A 472 40.904 -9.555 -21.043 1.00 8.37 O ANISOU 1167 O LEU A 472 1174 967 1039 -166 -127 167 O ATOM 1168 CB LEU A 472 41.526 -11.877 -18.777 1.00 8.22 C ANISOU 1168 CB LEU A 472 1132 985 1003 30 -19 41 C ATOM 1169 CG LEU A 472 41.545 -13.416 -18.667 1.00 7.91 C ANISOU 1169 CG LEU A 472 1021 973 1009 0 1 11 C ATOM 1170 CD1 LEU A 472 41.138 -13.846 -17.273 1.00 8.09 C ANISOU 1170 CD1 LEU A 472 1055 999 1018 -3 42 -6 C ATOM 1171 CD2 LEU A 472 40.688 -14.076 -19.725 1.00 7.87 C ANISOU 1171 CD2 LEU A 472 1005 957 1028 34 1 -20 C ATOM 1172 N CYS A 473 42.587 -8.982 -19.679 1.00 7.93 N ANISOU 1172 N CYS A 473 1013 1039 959 19 -40 60 N ATOM 1173 CA CYS A 473 42.399 -7.537 -19.873 1.00 8.17 C ANISOU 1173 CA CYS A 473 1023 1044 1036 -41 -27 126 C ATOM 1174 C CYS A 473 42.558 -7.170 -21.349 1.00 8.19 C ANISOU 1174 C CYS A 473 991 1078 1041 -45 6 103 C ATOM 1175 O CYS A 473 41.738 -6.415 -21.920 1.00 8.43 O ANISOU 1175 O CYS A 473 883 1370 949 -110 -59 225 O ATOM 1176 CB CYS A 473 43.366 -6.730 -19.009 1.00 8.46 C ANISOU 1176 CB CYS A 473 1042 1110 1062 -19 -23 59 C ATOM 1177 SG CYS A 473 42.990 -6.801 -17.240 1.00 8.85 S ANISOU 1177 SG CYS A 473 1032 1238 1091 -104 9 138 S ATOM 1178 N THR A 474 43.601 -7.728 -21.956 1.00 8.28 N ANISOU 1178 N THR A 474 1001 1080 1063 17 -26 101 N ATOM 1179 CA THR A 474 43.904 -7.518 -23.373 1.00 8.46 C ANISOU 1179 CA THR A 474 1059 1098 1056 -19 -6 16 C ATOM 1180 C THR A 474 42.778 -8.000 -24.276 1.00 8.06 C ANISOU 1180 C THR A 474 977 1036 1047 0 41 0 C ATOM 1181 O THR A 474 42.422 -7.309 -25.221 1.00 7.23 O ANISOU 1181 O THR A 474 781 821 1142 -27 72 3 O ATOM 1182 CB THR A 474 45.230 -8.218 -23.747 1.00 8.48 C ANISOU 1182 CB THR A 474 1070 1075 1075 -6 -14 41 C ATOM 1183 OG1 THR A 474 46.286 -7.607 -23.002 1.00 8.02 O ANISOU 1183 OG1 THR A 474 1055 956 1036 6 -33 119 O ATOM 1184 CG2 THR A 474 45.536 -8.148 -25.270 1.00 8.64 C ANISOU 1184 CG2 THR A 474 1120 1072 1088 -42 6 34 C ATOM 1185 N LEU A 475 42.245 -9.191 -23.996 1.00 7.98 N ANISOU 1185 N LEU A 475 1025 1006 1000 1 3 -9 N ATOM 1186 CA LEU A 475 41.176 -9.767 -24.829 1.00 8.01 C ANISOU 1186 CA LEU A 475 985 993 1064 12 28 -43 C ATOM 1187 C LEU A 475 39.896 -8.957 -24.739 1.00 7.63 C ANISOU 1187 C LEU A 475 951 946 1001 -23 29 -55 C ATOM 1188 O LEU A 475 39.243 -8.701 -25.748 1.00 7.21 O ANISOU 1188 O LEU A 475 974 769 996 84 99 -2 O ATOM 1189 CB LEU A 475 40.914 -11.228 -24.454 1.00 8.05 C ANISOU 1189 CB LEU A 475 1027 1005 1023 -15 23 -20 C ATOM 1190 CG LEU A 475 42.076 -12.155 -24.811 1.00 8.51 C ANISOU 1190 CG LEU A 475 1090 1025 1115 16 40 -6 C ATOM 1191 CD1 LEU A 475 41.894 -13.533 -24.161 1.00 8.48 C ANISOU 1191 CD1 LEU A 475 1083 999 1139 0 55 -27 C ATOM 1192 CD2 LEU A 475 42.254 -12.258 -26.321 1.00 9.07 C ANISOU 1192 CD2 LEU A 475 1208 1131 1106 10 -20 -19 C ATOM 1193 N ILE A 476 39.547 -8.561 -23.526 1.00 7.33 N ANISOU 1193 N ILE A 476 881 940 964 -53 -24 -61 N ATOM 1194 CA ILE A 476 38.391 -7.709 -23.309 1.00 7.45 C ANISOU 1194 CA ILE A 476 923 957 949 0 -48 -15 C ATOM 1195 C ILE A 476 38.578 -6.388 -24.053 1.00 7.59 C ANISOU 1195 C ILE A 476 929 1023 933 -50 -23 23 C ATOM 1196 O ILE A 476 37.680 -5.966 -24.799 1.00 7.86 O ANISOU 1196 O ILE A 476 953 1121 912 -146 -49 148 O ATOM 1197 CB ILE A 476 38.116 -7.485 -21.802 1.00 7.67 C ANISOU 1197 CB ILE A 476 941 1035 935 18 -30 52 C ATOM 1198 CG1 ILE A 476 37.619 -8.794 -21.190 1.00 7.63 C ANISOU 1198 CG1 ILE A 476 972 980 946 -7 -23 -12 C ATOM 1199 CG2 ILE A 476 37.074 -6.379 -21.581 1.00 7.98 C ANISOU 1199 CG2 ILE A 476 1030 997 1003 0 6 -38 C ATOM 1200 CD1 ILE A 476 37.702 -8.829 -19.668 1.00 8.01 C ANISOU 1200 CD1 ILE A 476 1041 1046 955 7 -55 41 C ATOM 1201 N ASN A 477 39.736 -5.753 -23.872 1.00 7.42 N ANISOU 1201 N ASN A 477 941 962 915 -55 -26 38 N ATOM 1202 CA ASN A 477 40.045 -4.486 -24.576 1.00 7.53 C ANISOU 1202 CA ASN A 477 936 911 1013 -41 -57 18 C ATOM 1203 C ASN A 477 39.928 -4.622 -26.082 1.00 7.85 C ANISOU 1203 C ASN A 477 979 987 1016 -20 -68 52 C ATOM 1204 O ASN A 477 39.355 -3.758 -26.754 1.00 7.82 O ANISOU 1204 O ASN A 477 1042 767 1159 -57 -145 -17 O ATOM 1205 CB ASN A 477 41.460 -4.008 -24.236 1.00 7.04 C ANISOU 1205 CB ASN A 477 928 835 910 -70 3 19 C ATOM 1206 CG ASN A 477 41.574 -3.431 -22.832 1.00 6.44 C ANISOU 1206 CG ASN A 477 837 695 912 -94 -36 29 C ATOM 1207 OD1 ASN A 477 40.576 -3.227 -22.123 1.00 5.73 O ANISOU 1207 OD1 ASN A 477 745 553 879 -263 -76 17 O ATOM 1208 ND2 ASN A 477 42.800 -3.160 -22.425 1.00 5.79 N ANISOU 1208 ND2 ASN A 477 804 614 781 -103 36 39 N ATOM 1209 N TYR A 478 40.469 -5.723 -26.598 1.00 8.83 N ANISOU 1209 N TYR A 478 1123 944 1286 -53 -67 -29 N ATOM 1210 CA TYR A 478 40.457 -6.003 -28.025 1.00 9.93 C ANISOU 1210 CA TYR A 478 1266 1220 1284 -86 -11 4 C ATOM 1211 C TYR A 478 39.037 -6.153 -28.540 1.00 9.27 C ANISOU 1211 C TYR A 478 1276 1030 1214 -128 -4 41 C ATOM 1212 O TYR A 478 38.671 -5.538 -29.522 1.00 8.40 O ANISOU 1212 O TYR A 478 1004 908 1277 -287 86 141 O ATOM 1213 CB TYR A 478 41.246 -7.271 -28.332 1.00 12.05 C ANISOU 1213 CB TYR A 478 1516 1281 1781 -29 21 -112 C ATOM 1214 CG TYR A 478 41.171 -7.610 -29.790 1.00 15.07 C ANISOU 1214 CG TYR A 478 2002 1900 1822 -70 116 -139 C ATOM 1215 CD1 TYR A 478 41.814 -6.812 -30.734 1.00 17.86 C ANISOU 1215 CD1 TYR A 478 2294 2173 2319 -328 280 -2 C ATOM 1216 CD2 TYR A 478 40.418 -8.707 -30.241 1.00 18.25 C ANISOU 1216 CD2 TYR A 478 2255 2406 2270 -458 -15 -161 C ATOM 1217 CE1 TYR A 478 41.743 -7.104 -32.083 1.00 21.38 C ANISOU 1217 CE1 TYR A 478 2775 2896 2453 -477 252 -218 C ATOM 1218 CE2 TYR A 478 40.341 -9.009 -31.584 1.00 21.58 C ANISOU 1218 CE2 TYR A 478 2827 3068 2301 -476 233 -375 C ATOM 1219 CZ TYR A 478 41.005 -8.196 -32.500 1.00 22.43 C ANISOU 1219 CZ TYR A 478 2814 2926 2779 -558 353 -305 C ATOM 1220 OH TYR A 478 40.932 -8.467 -33.829 1.00 24.24 O ANISOU 1220 OH TYR A 478 2725 3984 2499 -681 632 279 O ATOM 1221 N ALA A 479 38.241 -6.991 -27.877 1.00 8.92 N ANISOU 1221 N ALA A 479 1177 1108 1104 -113 13 -5 N ATOM 1222 CA ALA A 479 36.845 -7.167 -28.252 1.00 8.59 C ANISOU 1222 CA ALA A 479 1170 1033 1058 -22 -23 -14 C ATOM 1223 C ALA A 479 36.125 -5.823 -28.302 1.00 8.69 C ANISOU 1223 C ALA A 479 1257 977 1066 -55 -68 -8 C ATOM 1224 O ALA A 479 35.469 -5.493 -29.295 1.00 9.18 O ANISOU 1224 O ALA A 479 1390 1015 1082 44 -199 -184 O ATOM 1225 CB ALA A 479 36.137 -8.098 -27.278 1.00 8.15 C ANISOU 1225 CB ALA A 479 1093 942 1060 -35 -74 -35 C ATOM 1226 N ILE A 480 36.290 -5.038 -27.255 1.00 8.42 N ANISOU 1226 N ILE A 480 1170 1001 1028 -75 -27 -5 N ATOM 1227 CA ILE A 480 35.604 -3.758 -27.190 1.00 9.12 C ANISOU 1227 CA ILE A 480 1184 1082 1197 13 -111 -2 C ATOM 1228 C ILE A 480 35.977 -2.825 -28.345 1.00 9.22 C ANISOU 1228 C ILE A 480 1178 1126 1199 25 -98 9 C ATOM 1229 O ILE A 480 35.164 -2.158 -28.922 1.00 9.02 O ANISOU 1229 O ILE A 480 1100 964 1360 -35 -131 2 O ATOM 1230 CB ILE A 480 35.814 -3.087 -25.820 1.00 9.60 C ANISOU 1230 CB ILE A 480 1232 1204 1211 55 -133 -44 C ATOM 1231 CG1 ILE A 480 35.276 -4.018 -24.739 1.00 10.26 C ANISOU 1231 CG1 ILE A 480 1308 1238 1350 5 -87 9 C ATOM 1232 CG2 ILE A 480 35.170 -1.720 -25.797 1.00 9.78 C ANISOU 1232 CG2 ILE A 480 1264 1186 1266 26 -87 -61 C ATOM 1233 CD1 ILE A 480 33.802 -4.019 -24.614 1.00 10.74 C ANISOU 1233 CD1 ILE A 480 1336 1335 1409 -7 -145 35 C ATOM 1234 N MET A 481 37.262 -2.750 -28.621 1.00 9.17 N ANISOU 1234 N MET A 481 1173 1126 1183 54 -95 -3 N ATOM 1235 CA MET A 481 37.715 -1.883 -29.705 1.00 10.00 C ANISOU 1235 CA MET A 481 1313 1220 1265 14 -23 39 C ATOM 1236 C MET A 481 37.226 -2.369 -31.069 1.00 9.67 C ANISOU 1236 C MET A 481 1204 1189 1282 -3 -58 76 C ATOM 1237 O MET A 481 36.987 -1.543 -31.957 1.00 9.44 O ANISOU 1237 O MET A 481 1065 1104 1415 19 -142 92 O ATOM 1238 CB MET A 481 39.237 -1.625 -29.681 1.00 11.12 C ANISOU 1238 CB MET A 481 1346 1433 1444 -45 -10 56 C ATOM 1239 CG MET A 481 40.152 -2.796 -29.995 1.00 11.71 C ANISOU 1239 CG MET A 481 1365 1545 1540 -65 198 -11 C ATOM 1240 SD MET A 481 41.909 -2.346 -29.814 1.00 15.82 S ANISOU 1240 SD MET A 481 1505 2045 2461 -410 135 -139 S ATOM 1241 CE MET A 481 42.247 -2.684 -28.085 1.00 17.49 C ANISOU 1241 CE MET A 481 1941 2185 2518 -296 177 -30 C ATOM 1242 N LYS A 482 37.045 -3.684 -31.220 1.00 9.48 N ANISOU 1242 N LYS A 482 1205 1164 1231 50 -45 80 N ATOM 1243 CA LYS A 482 36.401 -4.266 -32.416 1.00 9.90 C ANISOU 1243 CA LYS A 482 1293 1195 1271 34 -49 42 C ATOM 1244 C LYS A 482 34.870 -4.183 -32.425 1.00 8.88 C ANISOU 1244 C LYS A 482 1283 970 1122 43 -86 66 C ATOM 1245 O LYS A 482 34.244 -4.666 -33.360 1.00 8.07 O ANISOU 1245 O LYS A 482 1161 802 1103 125 -28 34 O ATOM 1246 CB LYS A 482 36.812 -5.741 -32.582 1.00 11.10 C ANISOU 1246 CB LYS A 482 1553 1185 1479 35 -58 47 C ATOM 1247 CG LYS A 482 38.292 -5.968 -32.821 1.00 12.68 C ANISOU 1247 CG LYS A 482 1579 1562 1673 81 -65 25 C ATOM 1248 CD LYS A 482 38.815 -5.301 -34.078 1.00 14.96 C ANISOU 1248 CD LYS A 482 1939 1846 1895 -18 82 153 C ATOM 1249 CE LYS A 482 37.999 -5.651 -35.313 1.00 17.04 C ANISOU 1249 CE LYS A 482 2367 2035 2072 30 -67 -62 C ATOM 1250 NZ LYS A 482 38.832 -5.446 -36.527 1.00 20.21 N ANISOU 1250 NZ LYS A 482 3071 2302 2304 148 243 146 N ATOM 1251 N ARG A 483 34.274 -3.565 -31.406 1.00 8.70 N ANISOU 1251 N ARG A 483 1234 968 1103 39 -53 122 N ATOM 1252 CA ARG A 483 32.833 -3.418 -31.291 1.00 9.36 C ANISOU 1252 CA ARG A 483 1242 1125 1188 5 2 62 C ATOM 1253 C ARG A 483 32.128 -4.787 -31.178 1.00 9.48 C ANISOU 1253 C ARG A 483 1337 1107 1155 -4 -21 46 C ATOM 1254 O ARG A 483 31.052 -5.013 -31.750 1.00 9.18 O ANISOU 1254 O ARG A 483 1281 1212 993 62 56 116 O ATOM 1255 CB ARG A 483 32.288 -2.554 -32.444 1.00 9.88 C ANISOU 1255 CB ARG A 483 1294 1202 1256 46 -56 70 C ATOM 1256 CG ARG A 483 31.306 -1.485 -31.989 1.00 10.54 C ANISOU 1256 CG ARG A 483 1314 1305 1384 73 -19 7 C ATOM 1257 CD ARG A 483 30.900 -0.620 -33.171 1.00 11.05 C ANISOU 1257 CD ARG A 483 1451 1341 1404 -5 -22 65 C ATOM 1258 NE ARG A 483 29.933 -1.304 -34.034 1.00 12.03 N ANISOU 1258 NE ARG A 483 1442 1587 1540 -135 -60 103 N ATOM 1259 CZ ARG A 483 29.279 -0.747 -35.054 1.00 12.40 C ANISOU 1259 CZ ARG A 483 1560 1556 1594 -277 -175 115 C ATOM 1260 NH1 ARG A 483 28.421 -1.476 -35.764 1.00 14.27 N ANISOU 1260 NH1 ARG A 483 1817 1776 1827 -280 -312 -119 N ATOM 1261 NH2 ARG A 483 29.483 0.529 -35.385 1.00 8.54 N ANISOU 1261 NH2 ARG A 483 868 1393 981 -592 -361 -194 N ATOM 1262 N ILE A 484 32.745 -5.676 -30.399 1.00 9.28 N ANISOU 1262 N ILE A 484 1215 1109 1200 27 -25 7 N ATOM 1263 CA ILE A 484 32.223 -7.016 -30.135 1.00 9.75 C ANISOU 1263 CA ILE A 484 1283 1172 1246 -7 -15 84 C ATOM 1264 C ILE A 484 31.949 -7.140 -28.643 1.00 9.34 C ANISOU 1264 C ILE A 484 1225 1061 1262 -18 23 113 C ATOM 1265 O ILE A 484 32.815 -6.842 -27.822 1.00 9.21 O ANISOU 1265 O ILE A 484 1270 1144 1084 -118 92 196 O ATOM 1266 CB ILE A 484 33.236 -8.103 -30.560 1.00 10.68 C ANISOU 1266 CB ILE A 484 1300 1293 1463 38 -39 -24 C ATOM 1267 CG1 ILE A 484 33.456 -8.048 -32.076 1.00 11.94 C ANISOU 1267 CG1 ILE A 484 1498 1500 1536 -31 100 -6 C ATOM 1268 CG2 ILE A 484 32.758 -9.486 -30.117 1.00 10.63 C ANISOU 1268 CG2 ILE A 484 1342 1317 1379 61 -12 2 C ATOM 1269 CD1 ILE A 484 34.662 -8.832 -32.556 1.00 14.04 C ANISOU 1269 CD1 ILE A 484 1744 1763 1825 132 198 -98 C ATOM 1270 N GLY A 485 30.749 -7.600 -28.296 1.00 8.84 N ANISOU 1270 N GLY A 485 1203 909 1244 20 -25 178 N ATOM 1271 CA GLY A 485 30.418 -7.858 -26.905 1.00 9.14 C ANISOU 1271 CA GLY A 485 1224 1006 1240 -43 6 128 C ATOM 1272 C GLY A 485 30.229 -6.636 -26.042 1.00 9.57 C ANISOU 1272 C GLY A 485 1320 1092 1223 -97 -93 69 C ATOM 1273 O GLY A 485 30.280 -6.735 -24.810 1.00 9.79 O ANISOU 1273 O GLY A 485 1410 1062 1245 -163 -186 214 O ATOM 1274 N ARG A 486 29.964 -5.489 -26.669 1.00 9.33 N ANISOU 1274 N ARG A 486 1235 1091 1216 -106 -123 73 N ATOM 1275 CA ARG A 486 29.695 -4.265 -25.919 1.00 10.37 C ANISOU 1275 CA ARG A 486 1400 1217 1324 -25 -54 4 C ATOM 1276 C ARG A 486 28.369 -4.364 -25.181 1.00 10.80 C ANISOU 1276 C ARG A 486 1386 1336 1379 -22 -34 -113 C ATOM 1277 O ARG A 486 27.438 -5.008 -25.664 1.00 10.83 O ANISOU 1277 O ARG A 486 1627 1081 1404 -70 51 -366 O ATOM 1278 CB ARG A 486 29.691 -3.056 -26.856 1.00 10.22 C ANISOU 1278 CB ARG A 486 1400 1247 1236 -25 -36 0 C ATOM 1279 CG ARG A 486 31.066 -2.759 -27.398 1.00 10.23 C ANISOU 1279 CG ARG A 486 1426 1213 1247 -9 0 16 C ATOM 1280 CD ARG A 486 31.076 -1.414 -28.088 1.00 10.45 C ANISOU 1280 CD ARG A 486 1477 1193 1300 -4 -1 6 C ATOM 1281 NE ARG A 486 32.419 -1.045 -28.501 1.00 10.67 N ANISOU 1281 NE ARG A 486 1505 1245 1301 27 54 79 N ATOM 1282 CZ ARG A 486 32.788 0.175 -28.900 1.00 10.89 C ANISOU 1282 CZ ARG A 486 1492 1273 1371 39 141 105 C ATOM 1283 NH1 ARG A 486 31.902 1.167 -28.973 1.00 11.03 N ANISOU 1283 NH1 ARG A 486 1514 1332 1343 96 173 185 N ATOM 1284 NH2 ARG A 486 34.049 0.395 -29.253 1.00 10.32 N ANISOU 1284 NH2 ARG A 486 1440 1187 1294 32 85 69 N ATOM 1285 N ASP A 487 28.301 -3.767 -23.994 1.00 11.16 N ANISOU 1285 N ASP A 487 1532 1201 1505 0 -70 -217 N ATOM 1286 CA ASP A 487 27.027 -3.650 -23.277 1.00 12.75 C ANISOU 1286 CA ASP A 487 1667 1598 1577 -7 67 -172 C ATOM 1287 C ASP A 487 26.508 -2.204 -23.185 1.00 14.63 C ANISOU 1287 C ASP A 487 1852 1796 1908 260 205 -164 C ATOM 1288 O ASP A 487 25.464 -1.960 -22.591 1.00 15.65 O ANISOU 1288 O ASP A 487 2046 2034 1865 332 347 -337 O ATOM 1289 CB ASP A 487 27.110 -4.310 -21.891 1.00 12.05 C ANISOU 1289 CB ASP A 487 1488 1520 1572 94 -32 -189 C ATOM 1290 CG ASP A 487 28.042 -3.587 -20.934 1.00 11.23 C ANISOU 1290 CG ASP A 487 1325 1525 1414 154 21 -123 C ATOM 1291 OD1 ASP A 487 28.886 -2.776 -21.370 1.00 11.40 O ANISOU 1291 OD1 ASP A 487 1668 1492 1169 4 -13 -168 O ATOM 1292 OD2 ASP A 487 27.921 -3.840 -19.726 1.00 10.08 O ANISOU 1292 OD2 ASP A 487 866 1497 1467 180 -70 79 O ATOM 1293 N ARG A 488 27.235 -1.269 -23.787 1.00 17.83 N ANISOU 1293 N ARG A 488 2507 2241 2025 -22 452 -40 N ATOM 1294 CA ARG A 488 26.931 0.161 -23.728 1.00 22.32 C ANISOU 1294 CA ARG A 488 3212 2496 2771 502 355 54 C ATOM 1295 C ARG A 488 27.137 0.748 -25.108 1.00 25.48 C ANISOU 1295 C ARG A 488 3963 3151 2567 1013 96 122 C ATOM 1296 O ARG A 488 27.865 0.169 -25.919 1.00 24.37 O ANISOU 1296 O ARG A 488 4109 2597 2552 1420 343 842 O ATOM 1297 CB ARG A 488 27.904 0.875 -22.784 1.00 26.94 C ANISOU 1297 CB ARG A 488 3810 3133 3290 99 163 -336 C ATOM 1298 CG ARG A 488 27.659 0.682 -21.301 1.00 30.53 C ANISOU 1298 CG ARG A 488 4361 3761 3474 -7 230 -94 C ATOM 1299 CD ARG A 488 28.543 1.627 -20.491 1.00 34.35 C ANISOU 1299 CD ARG A 488 4788 4302 3959 -141 -73 -364 C ATOM 1300 NE ARG A 488 29.893 1.092 -20.252 1.00 35.55 N ANISOU 1300 NE ARG A 488 4840 4368 4298 98 515 -430 N ATOM 1301 CZ ARG A 488 30.997 1.819 -20.038 1.00 37.29 C ANISOU 1301 CZ ARG A 488 4826 4586 4756 71 773 -495 C ATOM 1302 NH1 ARG A 488 30.978 3.160 -20.054 1.00 38.22 N ANISOU 1302 NH1 ARG A 488 5243 4539 4738 -71 1126 -319 N ATOM 1303 NH2 ARG A 488 32.152 1.197 -19.812 1.00 37.82 N ANISOU 1303 NH2 ARG A 488 5287 4446 4635 269 345 -134 N ATOM 1304 OXT ARG A 488 26.636 1.827 -25.420 1.00 31.07 O ANISOU 1304 OXT ARG A 488 4886 3596 3320 1594 -105 258 O TER 1305 ARG A 488 ATOM 1306 O5' C B 1 37.653 6.754 -27.303 1.00 13.53 O ANISOU 1306 O5' C B 1 1677 1536 1925 234 18 -227 O ATOM 1307 C5' C B 1 37.469 5.963 -26.156 1.00 14.18 C ANISOU 1307 C5' C B 1 1737 1701 1949 48 -145 -109 C ATOM 1308 C4' C B 1 36.897 6.767 -25.024 1.00 13.89 C ANISOU 1308 C4' C B 1 1734 1648 1893 -24 -62 -44 C ATOM 1309 O4' C B 1 37.836 7.784 -24.600 1.00 13.74 O ANISOU 1309 O4' C B 1 1707 1706 1805 -34 -187 45 O ATOM 1310 C3' C B 1 35.582 7.500 -25.288 1.00 13.89 C ANISOU 1310 C3' C B 1 1874 1523 1877 66 -139 -12 C ATOM 1311 O3' C B 1 34.773 7.547 -24.115 1.00 15.07 O ANISOU 1311 O3' C B 1 2241 1528 1955 56 0 49 O ATOM 1312 C2' C B 1 36.061 8.896 -25.634 1.00 13.11 C ANISOU 1312 C2' C B 1 1707 1569 1706 108 12 84 C ATOM 1313 O2' C B 1 35.058 9.870 -25.518 1.00 13.87 O ANISOU 1313 O2' C B 1 2309 1186 1771 200 153 -34 O ATOM 1314 C1' C B 1 37.205 9.052 -24.638 1.00 13.83 C ANISOU 1314 C1' C B 1 1842 1633 1776 -48 -54 10 C ATOM 1315 N1 C B 1 38.174 10.048 -25.095 1.00 13.08 N ANISOU 1315 N1 C B 1 1731 1641 1594 -7 -96 35 N ATOM 1316 C2 C B 1 38.440 11.164 -24.305 1.00 14.31 C ANISOU 1316 C2 C B 1 1876 1803 1756 -112 -6 -99 C ATOM 1317 O2 C B 1 37.857 11.284 -23.223 1.00 15.82 O ANISOU 1317 O2 C B 1 2438 2072 1497 -273 -131 -387 O ATOM 1318 N3 C B 1 39.317 12.089 -24.752 1.00 14.08 N ANISOU 1318 N3 C B 1 1891 1750 1708 -158 -102 -112 N ATOM 1319 C4 C B 1 39.929 11.913 -25.922 1.00 14.00 C ANISOU 1319 C4 C B 1 1665 1841 1813 -63 -64 -70 C ATOM 1320 N4 C B 1 40.777 12.845 -26.327 1.00 15.60 N ANISOU 1320 N4 C B 1 2018 1962 1947 -279 -94 0 N ATOM 1321 C5 C B 1 39.659 10.789 -26.751 1.00 12.60 C ANISOU 1321 C5 C B 1 1432 1672 1681 129 -29 19 C ATOM 1322 C6 C B 1 38.790 9.889 -26.299 1.00 12.62 C ANISOU 1322 C6 C B 1 1558 1526 1709 117 -63 18 C ATOM 1323 P U B 2 33.503 6.600 -23.941 1.00 15.80 P ANISOU 1323 P U B 2 2149 1834 2019 85 -106 162 P ATOM 1324 OP1 U B 2 32.925 6.320 -25.271 1.00 15.83 O ANISOU 1324 OP1 U B 2 1944 1855 2214 83 -303 180 O ATOM 1325 OP2 U B 2 32.663 7.178 -22.873 1.00 15.39 O ANISOU 1325 OP2 U B 2 2013 1301 2532 352 -188 -143 O ATOM 1326 O5' U B 2 34.136 5.236 -23.417 1.00 13.46 O ANISOU 1326 O5' U B 2 1971 1516 1625 -28 -118 -135 O ATOM 1327 C5' U B 2 34.647 5.106 -22.084 1.00 11.29 C ANISOU 1327 C5' U B 2 1469 1230 1591 -100 -20 -109 C ATOM 1328 C4' U B 2 35.174 3.708 -21.887 1.00 10.40 C ANISOU 1328 C4' U B 2 1260 1242 1450 -155 2 -37 C ATOM 1329 O4' U B 2 34.068 2.749 -21.901 1.00 10.73 O ANISOU 1329 O4' U B 2 1391 1120 1565 -195 10 -78 O ATOM 1330 C3' U B 2 36.154 3.216 -22.958 1.00 10.28 C ANISOU 1330 C3' U B 2 1336 1214 1354 -169 46 23 C ATOM 1331 O3' U B 2 37.217 2.474 -22.373 1.00 9.45 O ANISOU 1331 O3' U B 2 1151 1102 1338 -217 198 -14 O ATOM 1332 C2' U B 2 35.304 2.249 -23.773 1.00 9.93 C ANISOU 1332 C2' U B 2 1338 1167 1268 -71 34 8 C ATOM 1333 O2' U B 2 36.027 1.268 -24.486 1.00 9.87 O ANISOU 1333 O2' U B 2 1336 1227 1187 11 -14 21 O ATOM 1334 C1' U B 2 34.474 1.630 -22.659 1.00 9.66 C ANISOU 1334 C1' U B 2 1182 1153 1335 -128 -7 1 C ATOM 1335 N1 U B 2 33.302 0.844 -23.073 1.00 9.35 N ANISOU 1335 N1 U B 2 1187 1096 1269 -92 -53 2 N ATOM 1336 C2 U B 2 33.108 -0.369 -22.440 1.00 9.28 C ANISOU 1336 C2 U B 2 1125 1161 1240 -118 -49 57 C ATOM 1337 O2 U B 2 33.835 -0.771 -21.547 1.00 9.79 O ANISOU 1337 O2 U B 2 1201 1185 1331 -159 -32 253 O ATOM 1338 N3 U B 2 32.018 -1.082 -22.875 1.00 9.13 N ANISOU 1338 N3 U B 2 1161 1007 1298 -119 -68 70 N ATOM 1339 C4 U B 2 31.136 -0.731 -23.879 1.00 9.01 C ANISOU 1339 C4 U B 2 1123 1050 1247 -142 -45 49 C ATOM 1340 O4 U B 2 30.205 -1.488 -24.163 1.00 8.53 O ANISOU 1340 O4 U B 2 1211 823 1204 -105 -71 100 O ATOM 1341 C5 U B 2 31.414 0.528 -24.500 1.00 9.04 C ANISOU 1341 C5 U B 2 1207 1065 1159 -71 -88 86 C ATOM 1342 C6 U B 2 32.466 1.252 -24.093 1.00 9.65 C ANISOU 1342 C6 U B 2 1240 1136 1288 -136 -74 84 C ATOM 1343 P U B 3 38.591 3.180 -22.023 1.00 10.17 P ANISOU 1343 P U B 3 1124 1256 1481 -195 183 -86 P ATOM 1344 OP1 U B 3 39.536 2.123 -21.601 1.00 10.93 O ANISOU 1344 OP1 U B 3 1169 1223 1761 -399 -176 129 O ATOM 1345 OP2 U B 3 38.304 4.320 -21.119 1.00 10.63 O ANISOU 1345 OP2 U B 3 1372 1046 1618 -654 410 -83 O ATOM 1346 O5' U B 3 39.037 3.800 -23.421 1.00 9.91 O ANISOU 1346 O5' U B 3 1112 1197 1456 -115 121 -44 O ATOM 1347 C5' U B 3 39.210 2.959 -24.578 1.00 9.97 C ANISOU 1347 C5' U B 3 1170 1327 1287 -102 42 4 C ATOM 1348 C4' U B 3 40.652 3.004 -25.032 1.00 9.67 C ANISOU 1348 C4' U B 3 1166 1312 1194 -90 5 66 C ATOM 1349 O4' U B 3 40.960 4.343 -25.495 1.00 9.75 O ANISOU 1349 O4' U B 3 1171 1348 1185 -77 -14 127 O ATOM 1350 C3' U B 3 41.701 2.696 -23.964 1.00 9.70 C ANISOU 1350 C3' U B 3 1235 1262 1185 -58 -28 54 C ATOM 1351 O3' U B 3 42.752 1.916 -24.502 1.00 9.15 O ANISOU 1351 O3' U B 3 1323 1153 998 0 -148 50 O ATOM 1352 C2' U B 3 42.257 4.067 -23.621 1.00 9.64 C ANISOU 1352 C2' U B 3 1213 1302 1147 -62 2 15 C ATOM 1353 O2' U B 3 43.532 3.991 -23.023 1.00 8.95 O ANISOU 1353 O2' U B 3 1276 1296 827 -179 -30 -129 O ATOM 1354 C1' U B 3 42.223 4.714 -24.999 1.00 9.99 C ANISOU 1354 C1' U B 3 1196 1447 1152 -112 7 57 C ATOM 1355 N1 U B 3 42.295 6.175 -25.003 1.00 9.92 N ANISOU 1355 N1 U B 3 1131 1484 1152 -179 114 200 N ATOM 1356 C2 U B 3 43.339 6.780 -25.681 1.00 11.06 C ANISOU 1356 C2 U B 3 1102 1962 1138 -219 166 235 C ATOM 1357 O2 U B 3 44.222 6.150 -26.250 1.00 11.73 O ANISOU 1357 O2 U B 3 1380 1911 1162 -24 261 436 O ATOM 1358 N3 U B 3 43.314 8.151 -25.662 1.00 11.73 N ANISOU 1358 N3 U B 3 864 2008 1585 -552 593 436 N ATOM 1359 C4 U B 3 42.379 8.962 -25.052 1.00 12.08 C ANISOU 1359 C4 U B 3 1271 1702 1614 -341 208 206 C ATOM 1360 O4 U B 3 42.494 10.184 -25.131 1.00 13.88 O ANISOU 1360 O4 U B 3 1758 1609 1907 -134 99 -34 O ATOM 1361 C5 U B 3 41.322 8.258 -24.390 1.00 10.55 C ANISOU 1361 C5 U B 3 1096 1629 1281 -176 119 226 C ATOM 1362 C6 U B 3 41.313 6.923 -24.395 1.00 8.91 C ANISOU 1362 C6 U B 3 684 1606 1093 -445 332 377 C ATOM 1363 P A B 4 42.639 0.338 -24.463 1.00 9.55 P ANISOU 1363 P A B 4 1258 1140 1228 137 -366 167 P ATOM 1364 OP1 A B 4 43.766 -0.214 -25.252 1.00 9.58 O ANISOU 1364 OP1 A B 4 1408 1098 1131 3 -266 -119 O ATOM 1365 OP2 A B 4 41.239 -0.054 -24.755 1.00 9.21 O ANISOU 1365 OP2 A B 4 1351 1003 1144 -102 -218 158 O ATOM 1366 O5' A B 4 42.799 0.036 -22.915 1.00 9.55 O ANISOU 1366 O5' A B 4 1313 1160 1155 -69 -186 142 O ATOM 1367 C5' A B 4 44.036 0.307 -22.236 1.00 9.02 C ANISOU 1367 C5' A B 4 1228 1059 1137 -15 -149 137 C ATOM 1368 C4' A B 4 43.758 0.267 -20.761 1.00 8.95 C ANISOU 1368 C4' A B 4 1202 1061 1135 -52 -143 46 C ATOM 1369 O4' A B 4 43.425 -1.094 -20.368 1.00 8.81 O ANISOU 1369 O4' A B 4 1149 1128 1069 -145 -130 70 O ATOM 1370 C3' A B 4 44.902 0.640 -19.830 1.00 9.44 C ANISOU 1370 C3' A B 4 1225 1191 1168 -130 -129 2 C ATOM 1371 O3' A B 4 45.037 2.054 -19.766 1.00 11.04 O ANISOU 1371 O3' A B 4 1587 1242 1362 -213 -321 65 O ATOM 1372 C2' A B 4 44.417 0.023 -18.526 1.00 9.14 C ANISOU 1372 C2' A B 4 1205 1151 1113 -75 -96 -78 C ATOM 1373 O2' A B 4 43.365 0.751 -17.933 1.00 8.43 O ANISOU 1373 O2' A B 4 1025 1165 1013 -206 -153 -166 O ATOM 1374 C1' A B 4 43.822 -1.299 -19.023 1.00 8.44 C ANISOU 1374 C1' A B 4 1100 1061 1047 -60 -56 39 C ATOM 1375 N9 A B 4 44.743 -2.433 -18.968 1.00 8.20 N ANISOU 1375 N9 A B 4 993 1139 984 -38 -23 5 N ATOM 1376 C8 A B 4 45.391 -3.083 -19.991 1.00 8.00 C ANISOU 1376 C8 A B 4 989 1032 1018 -24 -29 16 C ATOM 1377 N7 A B 4 46.139 -4.083 -19.591 1.00 7.36 N ANISOU 1377 N7 A B 4 889 949 956 -102 -25 -13 N ATOM 1378 C5 A B 4 45.951 -4.110 -18.217 1.00 6.97 C ANISOU 1378 C5 A B 4 805 890 951 -115 -16 -20 C ATOM 1379 C6 A B 4 46.454 -4.950 -17.210 1.00 6.84 C ANISOU 1379 C6 A B 4 818 855 923 -111 36 -18 C ATOM 1380 N6 A B 4 47.302 -5.958 -17.438 1.00 6.66 N ANISOU 1380 N6 A B 4 780 853 894 -101 34 63 N ATOM 1381 N1 A B 4 46.077 -4.698 -15.937 1.00 6.77 N ANISOU 1381 N1 A B 4 775 861 934 -159 93 45 N ATOM 1382 C2 A B 4 45.229 -3.689 -15.706 1.00 6.68 C ANISOU 1382 C2 A B 4 770 882 886 -148 26 -1 C ATOM 1383 N3 A B 4 44.690 -2.829 -16.567 1.00 7.04 N ANISOU 1383 N3 A B 4 759 978 937 -108 -41 -2 N ATOM 1384 C4 A B 4 45.089 -3.103 -17.821 1.00 7.33 C ANISOU 1384 C4 A B 4 823 983 978 -74 15 -13 C ATOM 1385 P A B 5 46.460 2.710 -19.458 1.00 13.75 P ANISOU 1385 P A B 5 2026 1457 1740 -726 -311 94 P ATOM 1386 OP1 A B 5 46.287 4.178 -19.443 1.00 14.97 O ANISOU 1386 OP1 A B 5 2147 1442 2098 -634 -637 18 O ATOM 1387 OP2 A B 5 47.464 2.087 -20.335 1.00 15.20 O ANISOU 1387 OP2 A B 5 1789 2003 1981 -608 -218 71 O ATOM 1388 O5' A B 5 46.817 2.160 -18.009 1.00 12.88 O ANISOU 1388 O5' A B 5 1694 1621 1576 -630 -282 -38 O ATOM 1389 C5' A B 5 46.080 2.591 -16.849 1.00 13.06 C ANISOU 1389 C5' A B 5 1704 1557 1701 -294 -235 58 C ATOM 1390 C4' A B 5 46.560 1.820 -15.648 1.00 12.50 C ANISOU 1390 C4' A B 5 1822 1431 1496 -345 -173 -50 C ATOM 1391 O4' A B 5 46.308 0.398 -15.842 1.00 11.62 O ANISOU 1391 O4' A B 5 1638 1306 1469 -160 -96 132 O ATOM 1392 C3' A B 5 48.062 1.889 -15.401 1.00 12.63 C ANISOU 1392 C3' A B 5 1848 1449 1502 -323 -222 -2 C ATOM 1393 O3' A B 5 48.408 3.096 -14.734 1.00 16.05 O ANISOU 1393 O3' A B 5 2528 1657 1913 -359 -518 -268 O ATOM 1394 C2' A B 5 48.286 0.640 -14.569 1.00 12.63 C ANISOU 1394 C2' A B 5 1792 1423 1583 -146 -184 -32 C ATOM 1395 O2' A B 5 47.816 0.769 -13.247 1.00 12.46 O ANISOU 1395 O2' A B 5 2053 1292 1386 -205 -337 214 O ATOM 1396 C1' A B 5 47.376 -0.356 -15.278 1.00 11.53 C ANISOU 1396 C1' A B 5 1640 1334 1404 -109 -85 55 C ATOM 1397 N9 A B 5 48.018 -1.145 -16.330 1.00 11.01 N ANISOU 1397 N9 A B 5 1435 1258 1489 56 -122 87 N ATOM 1398 C8 A B 5 47.983 -0.939 -17.687 1.00 8.91 C ANISOU 1398 C8 A B 5 1061 795 1527 503 -131 454 C ATOM 1399 N7 A B 5 48.609 -1.861 -18.379 1.00 10.56 N ANISOU 1399 N7 A B 5 1440 1210 1362 200 55 107 N ATOM 1400 C5 A B 5 49.089 -2.734 -17.413 1.00 10.69 C ANISOU 1400 C5 A B 5 1409 1206 1447 101 -20 162 C ATOM 1401 C6 A B 5 49.848 -3.917 -17.499 1.00 9.90 C ANISOU 1401 C6 A B 5 1266 1132 1363 -28 20 155 C ATOM 1402 N6 A B 5 50.276 -4.440 -18.648 1.00 10.10 N ANISOU 1402 N6 A B 5 1348 1108 1378 -20 -24 87 N ATOM 1403 N1 A B 5 50.179 -4.537 -16.344 1.00 9.38 N ANISOU 1403 N1 A B 5 1200 876 1484 -10 97 250 N ATOM 1404 C2 A B 5 49.763 -4.003 -15.189 1.00 10.20 C ANISOU 1404 C2 A B 5 1429 1076 1370 -100 43 219 C ATOM 1405 N3 A B 5 49.031 -2.908 -14.981 1.00 11.04 N ANISOU 1405 N3 A B 5 1559 1201 1434 7 -34 127 N ATOM 1406 C4 A B 5 48.728 -2.309 -16.147 1.00 11.33 C ANISOU 1406 C4 A B 5 1546 1311 1447 106 -19 172 C ATOM 1407 P A B 6 49.815 3.787 -15.004 1.00 27.87 P ANISOU 1407 P A B 6 4026 2659 3903 -2056 -326 -292 P ATOM 1408 OP1 A B 6 49.885 4.975 -14.123 1.00 27.70 O ANISOU 1408 OP1 A B 6 3183 2661 4678 -2166 -728 -593 O ATOM 1409 OP2 A B 6 49.984 3.952 -16.467 1.00 27.13 O ANISOU 1409 OP2 A B 6 4069 1970 4266 -1721 -45 0 O ATOM 1410 O5' A B 6 50.865 2.696 -14.499 1.00 33.28 O ANISOU 1410 O5' A B 6 4584 2612 5446 -1324 -76 -1337 O ATOM 1411 C5' A B 6 51.009 2.403 -13.092 1.00 50.62 C ANISOU 1411 C5' A B 6 6795 6101 6336 -891 -474 -26 C ATOM 1412 C4' A B 6 51.835 1.153 -12.874 1.00 57.41 C ANISOU 1412 C4' A B 6 7350 6736 7727 -393 -1259 -419 C ATOM 1413 O4' A B 6 51.237 0.032 -13.579 1.00 43.70 O ANISOU 1413 O4' A B 6 5249 6024 5332 -159 -592 611 O ATOM 1414 C3' A B 6 53.276 1.201 -13.371 1.00 64.70 C ANISOU 1414 C3' A B 6 8053 7887 8639 -1158 -381 120 C ATOM 1415 O3' A B 6 54.131 1.804 -12.403 1.00 68.90 O ANISOU 1415 O3' A B 6 9179 8300 8700 -1340 -761 27 O ATOM 1416 C2' A B 6 53.595 -0.275 -13.581 1.00 59.72 C ANISOU 1416 C2' A B 6 7206 7859 7625 -1381 -963 -302 C ATOM 1417 O2' A B 6 54.004 -0.964 -12.413 1.00 47.04 O ANISOU 1417 O2' A B 6 5915 3084 8871 -3224 -2071 -834 O ATOM 1418 C1' A B 6 52.254 -0.815 -14.082 1.00 43.43 C ANISOU 1418 C1' A B 6 6391 6090 4020 -224 -480 -153 C ATOM 1419 N9 A B 6 52.132 -0.882 -15.539 1.00 22.23 N ANISOU 1419 N9 A B 6 2225 2389 3832 -381 -352 -90 N ATOM 1420 C8 A B 6 51.487 -0.024 -16.397 1.00 20.23 C ANISOU 1420 C8 A B 6 2148 2385 3153 -194 -189 -413 C ATOM 1421 N7 A B 6 51.563 -0.380 -17.657 1.00 19.33 N ANISOU 1421 N7 A B 6 1809 2500 3033 -248 -264 -318 N ATOM 1422 C5 A B 6 52.293 -1.560 -17.626 1.00 20.51 C ANISOU 1422 C5 A B 6 2227 2665 2901 -25 -74 -42 C ATOM 1423 C6 A B 6 52.699 -2.450 -18.637 1.00 21.26 C ANISOU 1423 C6 A B 6 2450 2835 2793 69 -2 22 C ATOM 1424 N6 A B 6 52.432 -2.273 -19.934 1.00 21.08 N ANISOU 1424 N6 A B 6 2205 2818 2986 180 -349 -15 N ATOM 1425 N1 A B 6 53.418 -3.534 -18.268 1.00 25.99 N ANISOU 1425 N1 A B 6 3570 3252 3051 278 -69 701 N ATOM 1426 C2 A B 6 53.701 -3.704 -16.968 1.00 23.55 C ANISOU 1426 C2 A B 6 3153 2947 2845 -99 10 268 C ATOM 1427 N3 A B 6 53.358 -2.950 -15.926 1.00 21.94 N ANISOU 1427 N3 A B 6 2717 2526 3092 -388 -426 5 N ATOM 1428 C4 A B 6 52.649 -1.881 -16.327 1.00 21.53 C ANISOU 1428 C4 A B 6 2336 2768 3076 -258 -343 9 C ATOM 1429 P C B 7 55.337 2.755 -12.866 1.00 74.08 P ANISOU 1429 P C B 7 8286 9610 10248 -1270 -588 279 P ATOM 1430 OP1 C B 7 56.059 3.203 -11.647 1.00 77.82 O ANISOU 1430 OP1 C B 7 9208 10329 10031 -1666 -751 643 O ATOM 1431 OP2 C B 7 54.790 3.769 -13.803 1.00 74.14 O ANISOU 1431 OP2 C B 7 7669 9339 11163 -2080 -918 723 O ATOM 1432 O5' C B 7 56.281 1.769 -13.690 1.00 67.10 O ANISOU 1432 O5' C B 7 7790 7999 9703 -1647 -1342 -91 O ATOM 1433 C5' C B 7 57.009 0.713 -13.033 1.00 71.06 C ANISOU 1433 C5' C B 7 8372 8912 9716 -40 -475 -416 C ATOM 1434 C4' C B 7 57.729 -0.159 -14.039 1.00 68.79 C ANISOU 1434 C4' C B 7 8429 9006 8700 211 -693 -29 C ATOM 1435 O4' C B 7 56.774 -0.908 -14.839 1.00 58.60 O ANISOU 1435 O4' C B 7 6890 7627 7745 1120 -90 260 O ATOM 1436 C3' C B 7 58.582 0.552 -15.077 1.00 67.47 C ANISOU 1436 C3' C B 7 8365 9248 8019 272 -1007 27 C ATOM 1437 O3' C B 7 59.838 0.981 -14.558 1.00 63.15 O ANISOU 1437 O3' C B 7 8879 9583 5529 1035 -2092 538 O ATOM 1438 C2' C B 7 58.726 -0.525 -16.147 1.00 63.70 C ANISOU 1438 C2' C B 7 7492 8807 7902 210 -796 322 C ATOM 1439 O2' C B 7 59.755 -1.456 -15.875 1.00 63.01 O ANISOU 1439 O2' C B 7 7406 9440 7093 702 -22 171 O ATOM 1440 C1' C B 7 57.341 -1.183 -16.113 1.00 53.06 C ANISOU 1440 C1' C B 7 6688 7331 6142 1131 -1580 963 C ATOM 1441 N1 C B 7 56.436 -0.675 -17.168 1.00 29.03 N ANISOU 1441 N1 C B 7 3473 3551 4006 -120 131 -213 N ATOM 1442 C2 C B 7 56.458 -1.292 -18.428 1.00 24.55 C ANISOU 1442 C2 C B 7 2911 2669 3748 78 132 211 C ATOM 1443 O2 C B 7 57.203 -2.267 -18.607 1.00 26.74 O ANISOU 1443 O2 C B 7 2376 2886 4895 188 287 382 O ATOM 1444 N3 C B 7 55.654 -0.822 -19.410 1.00 26.12 N ANISOU 1444 N3 C B 7 3134 3146 3641 57 167 425 N ATOM 1445 C4 C B 7 54.867 0.234 -19.180 1.00 24.51 C ANISOU 1445 C4 C B 7 3443 3015 2854 -17 -58 165 C ATOM 1446 N4 C B 7 54.094 0.666 -20.178 1.00 24.44 N ANISOU 1446 N4 C B 7 3028 3050 3207 -180 -392 -122 N ATOM 1447 C5 C B 7 54.839 0.893 -17.915 1.00 25.31 C ANISOU 1447 C5 C B 7 3524 3156 2934 -214 -54 19 C ATOM 1448 C6 C B 7 55.637 0.413 -16.948 1.00 26.62 C ANISOU 1448 C6 C B 7 3568 3376 3169 -48 -167 40 C TER 1449 C B 7 HETATM 1450 O HOH A 501 42.027 -15.375 -28.976 1.00 21.46 O ANISOU 1450 O HOH A 501 2312 3229 2609 -146 -749 -519 O HETATM 1451 O HOH A 502 45.471 -1.098 -4.010 1.00 19.99 O ANISOU 1451 O HOH A 502 1342 2948 3302 -31 -59 -665 O HETATM 1452 O HOH A 503 45.852 -19.513 -12.159 1.00 8.93 O ANISOU 1452 O HOH A 503 784 1226 1381 -55 -259 -135 O HETATM 1453 O HOH A 504 30.233 -15.078 -7.020 1.00 23.90 O ANISOU 1453 O HOH A 504 4083 1996 3001 843 -359 -603 O HETATM 1454 O HOH A 505 32.448 3.625 8.757 1.00 17.38 O ANISOU 1454 O HOH A 505 1700 1437 3467 420 -1246 -200 O HETATM 1455 O HOH A 506 47.388 -11.912 -9.509 1.00 4.98 O ANISOU 1455 O HOH A 506 693 405 791 91 -251 177 O HETATM 1456 O HOH A 507 31.789 -21.981 -8.539 1.00 31.95 O ANISOU 1456 O HOH A 507 6675 3324 2141 -1009 160 -207 O HETATM 1457 O HOH A 508 29.018 3.712 -10.620 1.00 24.90 O ANISOU 1457 O HOH A 508 2607 3565 3288 -160 -600 -170 O HETATM 1458 O HOH A 509 31.686 -18.468 -4.082 1.00 15.33 O ANISOU 1458 O HOH A 509 1436 3045 1343 -778 717 -850 O HETATM 1459 O HOH A 510 34.267 -15.585 -22.941 1.00 13.48 O ANISOU 1459 O HOH A 510 1541 2958 623 551 670 516 O HETATM 1460 O HOH A 511 53.007 -16.782 -16.463 1.00 20.49 O ANISOU 1460 O HOH A 511 2820 2239 2724 -68 -481 -877 O HETATM 1461 O HOH A 512 26.392 -7.612 -17.918 1.00 23.90 O ANISOU 1461 O HOH A 512 3791 1612 3675 -1227 -478 -493 O HETATM 1462 O HOH A 513 44.343 -20.531 -17.599 1.00 11.03 O ANISOU 1462 O HOH A 513 2356 1013 818 647 482 -356 O HETATM 1463 O HOH A 514 48.232 -9.403 -22.515 1.00 12.54 O ANISOU 1463 O HOH A 514 1019 1477 2266 963 0 -165 O HETATM 1464 O HOH A 515 52.982 -5.494 -12.380 1.00 14.22 O ANISOU 1464 O HOH A 515 1793 1147 2461 238 366 849 O HETATM 1465 O HOH A 516 56.039 -7.511 -10.252 1.00 20.18 O ANISOU 1465 O HOH A 516 2366 1675 3626 226 -927 1019 O HETATM 1466 O HOH A 517 22.656 -8.911 -15.488 1.00 32.42 O ANISOU 1466 O HOH A 517 3156 4041 5119 1129 562 -1288 O HETATM 1467 O HOH A 518 46.978 -22.556 -11.884 1.00 23.30 O ANISOU 1467 O HOH A 518 1644 4015 3193 -54 118 -324 O HETATM 1468 O HOH A 519 34.089 2.429 -18.379 1.00 39.49 O ANISOU 1468 O HOH A 519 3622 9393 1990 2275 153 1842 O HETATM 1469 O HOH A 520 38.916 -26.287 -10.014 1.00 10.29 O ANISOU 1469 O HOH A 520 1438 649 1821 -605 204 261 O HETATM 1470 O HOH A 521 47.182 -5.144 -23.697 1.00 19.31 O ANISOU 1470 O HOH A 521 1880 2109 3346 514 1229 611 O HETATM 1471 O HOH A 522 25.602 -0.737 3.446 1.00 26.38 O ANISOU 1471 O HOH A 522 1360 4163 4500 -991 1439 -1928 O HETATM 1472 O HOH A 523 39.090 -15.024 3.532 1.00 10.19 O ANISOU 1472 O HOH A 523 2437 419 1013 -332 -356 -230 O HETATM 1473 O HOH A 524 34.837 -12.461 -3.562 1.00 10.26 O ANISOU 1473 O HOH A 524 678 1503 1715 -536 160 -298 O HETATM 1474 O HOH A 525 26.334 -3.463 -6.431 1.00 17.05 O ANISOU 1474 O HOH A 525 1574 3251 1653 -68 273 310 O HETATM 1475 O HOH A 526 49.869 -10.919 -10.593 1.00 5.29 O ANISOU 1475 O HOH A 526 286 270 1452 13 173 129 O HETATM 1476 O HOH A 527 29.877 -11.613 -4.672 1.00 26.14 O ANISOU 1476 O HOH A 527 5014 1675 3241 -467 106 -872 O HETATM 1477 O HOH A 528 49.466 -24.419 -12.849 1.00 27.81 O ANISOU 1477 O HOH A 528 2188 4030 4347 1037 -705 1414 O HETATM 1478 O HOH A 529 48.511 -2.537 -12.267 1.00 10.42 O ANISOU 1478 O HOH A 529 1929 586 1442 -675 45 -286 O HETATM 1479 O HOH A 530 43.763 -9.824 4.970 1.00 11.67 O ANISOU 1479 O HOH A 530 1717 1395 1321 237 146 381 O HETATM 1480 O HOH A 531 33.952 -21.635 -6.905 1.00 18.98 O ANISOU 1480 O HOH A 531 3714 1148 2350 -935 416 152 O HETATM 1481 O HOH A 532 33.253 2.604 -11.851 1.00 12.99 O ANISOU 1481 O HOH A 532 1666 1779 1489 974 431 -434 O HETATM 1482 O HOH A 533 52.097 -23.194 -12.931 1.00 29.23 O ANISOU 1482 O HOH A 533 3805 1954 5345 1384 -1284 604 O HETATM 1483 O HOH A 534 41.471 -6.084 -37.071 1.00 42.43 O ANISOU 1483 O HOH A 534 3418 3758 8945 -1191 -189 -2081 O HETATM 1484 O HOH A 535 34.144 -14.063 -5.513 1.00 19.31 O ANISOU 1484 O HOH A 535 2332 2014 2991 565 -413 -555 O HETATM 1485 O HOH A 536 35.984 -16.772 -29.727 1.00 17.03 O ANISOU 1485 O HOH A 536 1774 3595 1099 761 -690 399 O HETATM 1486 O HOH A 537 50.570 -1.195 -7.442 1.00 26.09 O ANISOU 1486 O HOH A 537 2915 3674 3322 -591 535 167 O HETATM 1487 O HOH A 538 44.654 -4.073 3.536 1.00 12.63 O ANISOU 1487 O HOH A 538 2066 854 1875 208 -71 -178 O HETATM 1488 O HOH A 539 60.901 -15.685 -9.006 1.00 33.23 O ANISOU 1488 O HOH A 539 3377 4192 5056 1711 -798 -1002 O HETATM 1489 O HOH A 540 47.186 -11.528 -0.649 1.00 9.03 O ANISOU 1489 O HOH A 540 1093 699 1638 365 153 659 O HETATM 1490 O HOH A 541 34.320 -21.861 -13.040 1.00 10.48 O ANISOU 1490 O HOH A 541 574 1511 1894 511 -169 -49 O HETATM 1491 O HOH A 542 51.714 -7.098 -19.464 1.00 19.93 O ANISOU 1491 O HOH A 542 3329 1751 2493 1018 -1421 884 O HETATM 1492 O HOH A 543 46.482 -18.803 -9.505 1.00 11.00 O ANISOU 1492 O HOH A 543 1123 974 2080 -275 -703 -371 O HETATM 1493 O HOH A 544 43.851 -1.353 -6.479 1.00 8.41 O ANISOU 1493 O HOH A 544 811 820 1565 528 -792 -639 O HETATM 1494 O HOH A 545 55.254 -23.384 -14.864 1.00 35.80 O ANISOU 1494 O HOH A 545 4979 2374 6247 -3030 410 768 O HETATM 1495 O HOH A 546 35.400 -16.628 -3.036 1.00 9.98 O ANISOU 1495 O HOH A 546 1561 1020 1212 87 318 394 O HETATM 1496 O HOH A 547 56.581 -10.102 -7.918 1.00 28.83 O ANISOU 1496 O HOH A 547 2999 2800 5153 1762 -487 809 O HETATM 1497 O HOH A 548 52.141 -14.849 -14.784 1.00 8.14 O ANISOU 1497 O HOH A 548 413 952 1726 -227 256 268 O HETATM 1498 O HOH A 549 47.389 -6.572 -20.394 1.00 8.99 O ANISOU 1498 O HOH A 549 1000 1655 759 -355 -559 -61 O HETATM 1499 O HOH A 550 34.160 4.099 -8.290 1.00 29.42 O ANISOU 1499 O HOH A 550 3884 2151 5140 2624 201 225 O HETATM 1500 O HOH A 551 50.669 -21.174 -7.999 1.00 17.28 O ANISOU 1500 O HOH A 551 2458 1868 2237 1104 -532 521 O HETATM 1501 O HOH A 552 59.267 -23.351 -11.915 1.00 13.58 O ANISOU 1501 O HOH A 552 1956 732 2469 324 -653 758 O HETATM 1502 O HOH A 553 49.109 -18.822 -8.794 1.00 16.61 O ANISOU 1502 O HOH A 553 2454 2208 1649 -412 -150 -586 O HETATM 1503 O HOH A 554 41.369 -15.323 1.374 1.00 11.66 O ANISOU 1503 O HOH A 554 1464 964 2000 122 154 617 O HETATM 1504 O HOH A 555 43.846 -5.219 -26.565 1.00 17.58 O ANISOU 1504 O HOH A 555 1230 2293 3155 12 585 1436 O HETATM 1505 O HOH A 556 32.119 -0.526 -0.207 1.00 12.47 O ANISOU 1505 O HOH A 556 2447 1377 915 162 -108 4 O HETATM 1506 O HOH A 557 51.369 -7.704 -3.311 1.00 11.71 O ANISOU 1506 O HOH A 557 1718 1452 1280 637 -855 324 O HETATM 1507 O HOH A 558 37.400 -27.126 -17.255 1.00 21.72 O ANISOU 1507 O HOH A 558 3223 3256 1772 -688 -660 -1149 O HETATM 1508 O HOH A 559 37.504 -29.551 -4.755 1.00 27.95 O ANISOU 1508 O HOH A 559 3332 2527 4761 -1020 -277 1473 O HETATM 1509 O HOH A 560 22.916 -1.740 1.956 1.00 36.94 O ANISOU 1509 O HOH A 560 1039 6579 6418 67 1089 980 O HETATM 1510 O HOH A 561 30.393 -6.568 6.385 1.00 24.08 O ANISOU 1510 O HOH A 561 4399 2788 1960 -500 137 288 O HETATM 1511 O HOH A 562 42.002 -15.906 -3.892 1.00 14.33 O ANISOU 1511 O HOH A 562 582 2679 2180 -86 -673 52 O HETATM 1512 O HOH A 563 49.945 -23.510 -17.884 1.00 48.16 O ANISOU 1512 O HOH A 563 5051 6392 6853 2647 2244 -2317 O HETATM 1513 O HOH A 564 22.609 -0.997 -3.080 1.00 20.46 O ANISOU 1513 O HOH A 564 1288 4733 1752 -1316 -808 -290 O HETATM 1514 O HOH A 565 44.394 0.934 -13.219 1.00 20.73 O ANISOU 1514 O HOH A 565 4162 1385 2329 152 497 -163 O HETATM 1515 O HOH A 566 30.859 -21.798 -18.494 1.00 17.65 O ANISOU 1515 O HOH A 566 3151 1368 2188 267 990 664 O HETATM 1516 O HOH A 567 37.659 -28.493 -14.634 1.00 19.90 O ANISOU 1516 O HOH A 567 2009 633 4916 557 85 -608 O HETATM 1517 O HOH A 568 46.480 -21.787 -14.709 1.00 22.56 O ANISOU 1517 O HOH A 568 2220 2299 4050 -869 678 1449 O HETATM 1518 O HOH A 569 29.238 -4.928 -29.457 1.00 7.77 O ANISOU 1518 O HOH A 569 1284 937 729 -531 -451 -105 O HETATM 1519 O HOH A 570 33.931 -23.357 -9.727 1.00 29.28 O ANISOU 1519 O HOH A 570 3922 4728 2475 -2443 -56 946 O HETATM 1520 O HOH A 571 32.361 -22.359 -22.843 1.00 14.07 O ANISOU 1520 O HOH A 571 542 2359 2442 613 -535 -148 O HETATM 1521 O HOH A 572 21.671 -7.423 2.670 1.00 45.12 O ANISOU 1521 O HOH A 572 2518 9071 5553 -2412 96 -2353 O HETATM 1522 O HOH A 573 39.085 -15.942 -28.552 1.00 11.42 O ANISOU 1522 O HOH A 573 2261 321 1755 -325 -381 -85 O HETATM 1523 O HOH A 574 31.715 -19.191 2.657 1.00 31.89 O ANISOU 1523 O HOH A 574 5515 2639 3962 -376 -412 737 O HETATM 1524 O HOH A 575 32.277 -17.383 0.627 1.00 15.84 O ANISOU 1524 O HOH A 575 3223 1500 1294 29 -652 -705 O HETATM 1525 O HOH A 576 33.507 -18.375 -2.080 1.00 20.52 O ANISOU 1525 O HOH A 576 1558 3403 2833 25 -509 421 O HETATM 1526 O HOH A 577 29.010 -18.828 -2.835 1.00 29.24 O ANISOU 1526 O HOH A 577 3008 3143 4957 1236 849 -2627 O HETATM 1527 O HOH A 578 58.401 -6.175 -11.553 1.00 27.97 O ANISOU 1527 O HOH A 578 6107 850 3670 -1455 -2156 1321 O HETATM 1528 O HOH A 579 44.410 -7.109 4.978 1.00 11.19 O ANISOU 1528 O HOH A 579 1515 1274 1462 470 420 -213 O HETATM 1529 O HOH A 580 42.120 3.958 -10.135 1.00 37.27 O ANISOU 1529 O HOH A 580 5667 2315 6176 879 -384 942 O HETATM 1530 O HOH A 581 48.930 -10.579 -24.723 1.00 17.43 O ANISOU 1530 O HOH A 581 1043 3107 2469 -186 -545 876 O HETATM 1531 O HOH A 582 27.549 -0.989 -18.532 1.00 38.19 O ANISOU 1531 O HOH A 582 5103 5229 4175 -537 -641 -1239 O HETATM 1532 O HOH A 583 57.393 -16.962 -4.179 1.00 16.95 O ANISOU 1532 O HOH A 583 3341 1281 1817 734 -705 -31 O HETATM 1533 O HOH A 584 21.785 -14.704 3.642 1.00 34.91 O ANISOU 1533 O HOH A 584 1621 5728 5916 -400 -2183 511 O HETATM 1534 O HOH A 585 37.208 -6.740 -39.005 1.00 33.40 O ANISOU 1534 O HOH A 585 2973 3986 5731 1298 2365 -318 O HETATM 1535 O HOH A 586 26.728 -9.305 3.901 1.00 28.97 O ANISOU 1535 O HOH A 586 3814 1249 5941 475 990 560 O HETATM 1536 O HOH A 587 50.947 -7.479 1.127 1.00 35.65 O ANISOU 1536 O HOH A 587 4142 3407 5995 -1135 1047 1306 O HETATM 1537 O HOH A 588 26.293 -13.038 -4.924 1.00 28.52 O ANISOU 1537 O HOH A 588 5273 872 4692 -1751 -518 -4 O HETATM 1538 O HOH A 589 31.817 -12.790 -6.230 1.00 33.59 O ANISOU 1538 O HOH A 589 3224 4501 5036 -1514 77 541 O HETATM 1539 O HOH A 590 37.876 -10.239 -34.575 1.00 24.23 O ANISOU 1539 O HOH A 590 4445 2857 1902 1056 -259 -1105 O HETATM 1540 O HOH A 591 29.957 3.493 -25.647 1.00 27.61 O ANISOU 1540 O HOH A 591 3572 3726 3192 -679 -759 2062 O HETATM 1541 O HOH A 592 47.853 -23.824 -15.365 1.00 32.10 O ANISOU 1541 O HOH A 592 2938 2218 7039 -222 1804 2995 O HETATM 1542 O HOH A 593 49.809 -7.282 -21.513 1.00 13.71 O ANISOU 1542 O HOH A 593 1048 2122 2037 -564 541 340 O HETATM 1543 O HOH A 594 38.534 -11.448 -28.334 1.00 38.82 O ANISOU 1543 O HOH A 594 4596 3610 6544 239 -568 302 O HETATM 1544 O HOH A 595 31.017 -9.996 9.011 1.00 45.30 O ANISOU 1544 O HOH A 595 3765 7691 5753 -898 143 1128 O HETATM 1545 O HOH A 596 35.242 -24.069 -6.187 1.00 26.97 O ANISOU 1545 O HOH A 596 4011 3030 3206 316 -175 -226 O HETATM 1546 O HOH A 597 22.873 -10.941 5.030 1.00 37.19 O ANISOU 1546 O HOH A 597 7049 3855 3226 1575 22 1026 O HETATM 1547 O HOH A 598 38.453 1.027 -27.810 1.00 16.80 O ANISOU 1547 O HOH A 598 1177 3000 2205 -536 767 707 O HETATM 1548 O HOH A 599 32.808 4.122 -14.596 1.00 40.29 O ANISOU 1548 O HOH A 599 5443 4169 5694 235 255 626 O HETATM 1549 O HOH A 600 48.394 -1.317 4.613 1.00 20.64 O ANISOU 1549 O HOH A 600 1331 3136 3372 1762 -675 -1039 O HETATM 1550 O HOH A 601 23.883 -4.415 -16.906 1.00 26.65 O ANISOU 1550 O HOH A 601 1754 5493 2876 -1193 -576 -1720 O HETATM 1551 O HOH A 602 31.851 -21.099 -4.955 1.00 22.59 O ANISOU 1551 O HOH A 602 3160 2056 3365 -95 -553 -212 O HETATM 1552 O HOH A 603 27.259 0.230 -30.479 1.00 43.19 O ANISOU 1552 O HOH A 603 10088 3754 2568 3003 2591 1075 O HETATM 1553 O HOH A 604 49.820 -25.656 -16.045 1.00 40.02 O ANISOU 1553 O HOH A 604 2746 2904 9555 372 -2160 -854 O HETATM 1554 O HOH A 605 58.922 -18.745 -2.799 1.00 20.30 O ANISOU 1554 O HOH A 605 4564 1081 2067 1489 252 -141 O HETATM 1555 O HOH A 606 32.648 8.634 -9.249 1.00 34.97 O ANISOU 1555 O HOH A 606 2294 4559 6434 147 -793 -181 O HETATM 1556 O HOH B 101 43.351 -0.479 -15.582 1.00 15.91 O ANISOU 1556 O HOH B 101 1831 2808 1404 185 636 319 O HETATM 1557 O HOH B 102 36.268 2.463 -26.857 1.00 16.92 O ANISOU 1557 O HOH B 102 3021 1389 2019 786 -147 394 O HETATM 1558 O HOH B 103 39.122 -1.025 -26.063 1.00 9.81 O ANISOU 1558 O HOH B 103 802 1851 1073 -277 -31 340 O HETATM 1559 O HOH B 104 32.686 3.772 -26.411 1.00 20.52 O ANISOU 1559 O HOH B 104 3390 2076 2327 366 366 355 O HETATM 1560 O HOH B 105 47.564 0.899 -22.900 1.00 18.41 O ANISOU 1560 O HOH B 105 1080 3036 2876 -1196 19 358 O HETATM 1561 O HOH B 106 50.444 0.733 -20.040 1.00 40.65 O ANISOU 1561 O HOH B 106 5465 3360 6621 -1319 371 2571 O HETATM 1562 O HOH B 107 49.205 -3.825 -21.346 1.00 26.72 O ANISOU 1562 O HOH B 107 3078 4954 2118 -787 -37 678 O HETATM 1563 O HOH B 108 54.914 -3.602 -13.429 1.00 24.17 O ANISOU 1563 O HOH B 108 1679 4610 2891 -987 -95 -949 O HETATM 1564 O HOH B 109 58.142 5.143 -10.680 1.00 45.71 O ANISOU 1564 O HOH B 109 12590 1199 3575 897 -65 -1715 O HETATM 1565 O HOH B 110 48.086 -1.233 -21.371 1.00 31.14 O ANISOU 1565 O HOH B 110 5065 2448 4317 -1910 1538 463 O MASTER 293 0 0 4 6 0 0 6 1563 2 0 15 END
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Related entries of code: 5dno
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5eim
RCSB PDB
PDBbind
163aa, >5EIM_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5dno
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
YTH domain-containing protein Mmi1
Ligand Name
8-mer RNA (5-CUUAAACC-3)
EC.Number
E.C.-.-.-.-
Resolution
1.8(Å)
Affinity (Kd/Ki/IC50)
Kd=1.8uM
Release Year
2016
Protein/NA Sequence
Check fasta file
Primary Reference
(2016) Nucleic Acids Res. Vol. 44: pp. 969-982
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
O74958
Entrez Gene ID
NCBI Entrez Gene ID:
2539540
ASD
Information of known allosteric effects of PDB entries
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