Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 23-MAY-16 5K5H TITLE HOMO SAPIENS CCCTC-BINDING FACTOR (CTCF) ZNF4-7 AND DNA COMPLEX TITLE 2 STRUCTURE COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTIONAL REPRESSOR CTCF; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: UNP RESIDUES 348-464; COMPND 5 SYNONYM: 11-ZINC FINGER PROTEIN,CCCTC-BINDING FACTOR,CTCFL PARALOG; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*C)-3'); COMPND 9 CHAIN: B; COMPND 10 ENGINEERED: YES; COMPND 11 MOL_ID: 3; COMPND 12 MOLECULE: DNA (5'-D(*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*G)-3'); COMPND 13 CHAIN: C; COMPND 14 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: CTCF; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21 (DE3) RIL-CODON PLUS; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PGEX-6P-1; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PXC1202; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 14 ORGANISM_TAXID: 32630; SOURCE 15 MOL_ID: 3; SOURCE 16 SYNTHETIC: YES; SOURCE 17 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 18 ORGANISM_TAXID: 32630 KEYWDS CCCTC-BINDING FACTOR, CTCF, ZINC FINGER, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR H.HASHIMOTO,X.CHENG REVDAT 5 25-DEC-19 5K5H 1 REMARK REVDAT 4 20-SEP-17 5K5H 1 REMARK REVDAT 3 14-JUN-17 5K5H 1 JRNL REVDAT 2 07-JUN-17 5K5H 1 JRNL REVDAT 1 24-MAY-17 5K5H 0 JRNL AUTH H.HASHIMOTO,D.WANG,J.R.HORTON,X.ZHANG,V.G.CORCES,X.CHENG JRNL TITL STRUCTURAL BASIS FOR THE VERSATILE AND METHYLATION-DEPENDENT JRNL TITL 2 BINDING OF CTCF TO DNA. JRNL REF MOL. CELL V. 66 711 2017 JRNL REFN ISSN 1097-4164 JRNL PMID 28529057 JRNL DOI 10.1016/J.MOLCEL.2017.05.004 REMARK 2 REMARK 2 RESOLUTION. 3.11 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (DEV_2400: ???) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : NULL REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 3.11 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 50.32 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.380 REMARK 3 COMPLETENESS FOR RANGE (%) : 72.5 REMARK 3 NUMBER OF REFLECTIONS : 44172 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.240 REMARK 3 R VALUE (WORKING SET) : 0.237 REMARK 3 FREE R VALUE : 0.264 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 10.040 REMARK 3 FREE R VALUE TEST SET COUNT : 340 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 50.3274 - 3.9155 1.00 2190 234 0.2299 0.2490 REMARK 3 2 3.9155 - 3.1080 0.43 855 106 0.2533 0.3024 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : NULL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.310 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 24.610 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.004 1535 REMARK 3 ANGLE : 0.454 2149 REMARK 3 CHIRALITY : 0.031 231 REMARK 3 PLANARITY : 0.002 182 REMARK 3 DIHEDRAL : 23.758 607 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 7 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 350 THROUGH 371 ) REMARK 3 ORIGIN FOR THE GROUP (A): -20.5408 18.6519 3.6740 REMARK 3 T TENSOR REMARK 3 T11: 0.9230 T22: 0.5574 REMARK 3 T33: 0.5064 T12: -0.1363 REMARK 3 T13: -0.0939 T23: -0.0100 REMARK 3 L TENSOR REMARK 3 L11: 2.6528 L22: 4.3272 REMARK 3 L33: 6.3480 L12: -1.7544 REMARK 3 L13: -2.8453 L23: 1.1622 REMARK 3 S TENSOR REMARK 3 S11: -0.6613 S12: -0.2785 S13: 0.9580 REMARK 3 S21: -0.1616 S22: 0.9110 S23: -0.3226 REMARK 3 S31: -1.6632 S32: 1.9372 S33: -0.0232 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 372 THROUGH 381 ) REMARK 3 ORIGIN FOR THE GROUP (A): -6.9964 12.2671 -1.4934 REMARK 3 T TENSOR REMARK 3 T11: 0.7461 T22: 1.0546 REMARK 3 T33: 1.7809 T12: -0.2336 REMARK 3 T13: 0.0351 T23: -0.2575 REMARK 3 L TENSOR REMARK 3 L11: 7.2985 L22: 5.4137 REMARK 3 L33: 4.0709 L12: -6.2091 REMARK 3 L13: -3.4729 L23: 3.5189 REMARK 3 S TENSOR REMARK 3 S11: 0.3514 S12: 0.0843 S13: 0.1133 REMARK 3 S21: 0.6139 S22: 0.5536 S23: 0.4219 REMARK 3 S31: 0.9419 S32: -0.1157 S33: -0.7087 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 382 THROUGH 429 ) REMARK 3 ORIGIN FOR THE GROUP (A): -16.7019 -5.6657 -6.8054 REMARK 3 T TENSOR REMARK 3 T11: 0.2202 T22: 0.8967 REMARK 3 T33: 0.3091 T12: 0.1416 REMARK 3 T13: 0.1374 T23: -0.1753 REMARK 3 L TENSOR REMARK 3 L11: 1.8700 L22: 2.0365 REMARK 3 L33: 2.1891 L12: -0.7990 REMARK 3 L13: 0.8655 L23: 0.5770 REMARK 3 S TENSOR REMARK 3 S11: 0.1816 S12: -0.3145 S13: 0.1511 REMARK 3 S21: 0.2531 S22: 0.4016 S23: -0.2950 REMARK 3 S31: 0.0671 S32: 0.1809 S33: 0.0389 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 430 THROUGH 434 ) REMARK 3 ORIGIN FOR THE GROUP (A): -36.3813 -10.0842 -17.0542 REMARK 3 T TENSOR REMARK 3 T11: 1.0063 T22: 1.6830 REMARK 3 T33: 1.1299 T12: -0.4875 REMARK 3 T13: -0.3480 T23: 0.0516 REMARK 3 L TENSOR REMARK 3 L11: 0.1142 L22: 2.5113 REMARK 3 L33: 0.3473 L12: -0.1420 REMARK 3 L13: 0.0143 L23: -0.1563 REMARK 3 S TENSOR REMARK 3 S11: 0.2408 S12: 0.8668 S13: 0.4771 REMARK 3 S21: -0.8703 S22: -0.3270 S23: 0.9381 REMARK 3 S31: 0.6594 S32: 0.4328 S33: 0.0667 REMARK 3 TLS GROUP : 5 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 435 THROUGH 460 ) REMARK 3 ORIGIN FOR THE GROUP (A): -30.1021 6.3118 -25.4887 REMARK 3 T TENSOR REMARK 3 T11: 0.4641 T22: 1.1024 REMARK 3 T33: 0.7428 T12: 0.1273 REMARK 3 T13: 0.2270 T23: 0.0282 REMARK 3 L TENSOR REMARK 3 L11: 1.0057 L22: 8.0986 REMARK 3 L33: 6.4139 L12: 0.7337 REMARK 3 L13: -2.5396 L23: -1.6671 REMARK 3 S TENSOR REMARK 3 S11: 1.0653 S12: 0.6412 S13: 1.4658 REMARK 3 S21: -1.0307 S22: -0.0871 S23: 0.7865 REMARK 3 S31: -0.7339 S32: -1.3184 S33: -0.8910 REMARK 3 TLS GROUP : 6 REMARK 3 SELECTION: CHAIN 'B' AND (RESID 1 THROUGH 13 ) REMARK 3 ORIGIN FOR THE GROUP (A): -21.1445 2.9108 -3.2958 REMARK 3 T TENSOR REMARK 3 T11: 0.3158 T22: 0.6203 REMARK 3 T33: 0.2360 T12: 0.0700 REMARK 3 T13: 0.1024 T23: -0.0961 REMARK 3 L TENSOR REMARK 3 L11: 1.7417 L22: 1.6885 REMARK 3 L33: 3.9089 L12: -0.7070 REMARK 3 L13: -1.5725 L23: 1.9688 REMARK 3 S TENSOR REMARK 3 S11: 0.2305 S12: 0.1634 S13: 0.0702 REMARK 3 S21: -0.2046 S22: 0.2224 S23: -0.0947 REMARK 3 S31: -0.5217 S32: 0.3878 S33: -0.3040 REMARK 3 TLS GROUP : 7 REMARK 3 SELECTION: CHAIN 'C' AND (RESID 3 THROUGH 15 ) REMARK 3 ORIGIN FOR THE GROUP (A): -19.8157 2.6132 -7.6292 REMARK 3 T TENSOR REMARK 3 T11: 0.3488 T22: 0.9573 REMARK 3 T33: 0.3265 T12: 0.1456 REMARK 3 T13: 0.0214 T23: -0.0522 REMARK 3 L TENSOR REMARK 3 L11: 0.7136 L22: 3.3001 REMARK 3 L33: 7.1147 L12: -1.2476 REMARK 3 L13: -2.2386 L23: 3.5920 REMARK 3 S TENSOR REMARK 3 S11: 0.2579 S12: 0.5414 S13: 0.1767 REMARK 3 S21: -0.6038 S22: -0.1021 S23: -0.3077 REMARK 3 S31: -0.9773 S32: 0.5504 S33: -0.2650 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 5K5H COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 24-MAY-16. REMARK 100 THE DEPOSITION ID IS D_1000221738. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 26-FEB-15 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 5.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : APS REMARK 200 BEAMLINE : 22-ID REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 1.27046 REMARK 200 MONOCHROMATOR : SI (1 1 1) REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : CCD REMARK 200 DETECTOR MANUFACTURER : RAYONIX MX300-HS REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS REMARK 200 DATA SCALING SOFTWARE : XDS REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 44172 REMARK 200 RESOLUTION RANGE HIGH (A) : 3.108 REMARK 200 RESOLUTION RANGE LOW (A) : 50.321 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 70.8 REMARK 200 DATA REDUNDANCY : 7.700 REMARK 200 R MERGE (I) : 0.08800 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 17.5600 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.11 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 3.19 REMARK 200 COMPLETENESS FOR SHELL (%) : 4.7 REMARK 200 DATA REDUNDANCY IN SHELL : 7.90 REMARK 200 R MERGE FOR SHELL (I) : 0.05900 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: SAD REMARK 200 SOFTWARE USED: AUTOSOL REMARK 200 STARTING MODEL: NULL REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 55.55 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.77 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 25% (W/V) POLYETHYLENE GLYCOL 3350, REMARK 280 0.2 M AMMONIUM ACETATE, 0.1 M BIS-TRIS HCL, PH 5.5, VAPOR REMARK 280 DIFFUSION, SITTING DROP, TEMPERATURE 289K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 41 21 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z+1/2 REMARK 290 3555 -Y+1/2,X+1/2,Z+1/4 REMARK 290 4555 Y+1/2,-X+1/2,Z+3/4 REMARK 290 5555 -X+1/2,Y+1/2,-Z+1/4 REMARK 290 6555 X+1/2,-Y+1/2,-Z+3/4 REMARK 290 7555 Y,X,-Z REMARK 290 8555 -Y,-X,-Z+1/2 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 83.08500 REMARK 290 SMTRY1 3 0.000000 -1.000000 0.000000 26.40000 REMARK 290 SMTRY2 3 1.000000 0.000000 0.000000 26.40000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 41.54250 REMARK 290 SMTRY1 4 0.000000 1.000000 0.000000 26.40000 REMARK 290 SMTRY2 4 -1.000000 0.000000 0.000000 26.40000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 124.62750 REMARK 290 SMTRY1 5 -1.000000 0.000000 0.000000 26.40000 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 26.40000 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 41.54250 REMARK 290 SMTRY1 6 1.000000 0.000000 0.000000 26.40000 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 26.40000 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 124.62750 REMARK 290 SMTRY1 7 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY2 7 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY2 8 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 83.08500 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 4460 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 10700 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -24.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 343 REMARK 465 PRO A 344 REMARK 465 LEU A 345 REMARK 465 GLY A 346 REMARK 465 SER A 347 REMARK 465 GLU A 348 REMARK 465 LYS A 349 REMARK 465 SER A 461 REMARK 465 TYR A 462 REMARK 465 ILE A 463 REMARK 465 GLU A 464 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O LEU A 427 OG1 THR A 431 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 501 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 353 SG REMARK 620 2 CYS A 356 SG 113.3 REMARK 620 3 HIS A 369 NE2 98.7 77.1 REMARK 620 4 HIS A 373 NE2 138.9 107.5 85.8 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 502 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 381 SG REMARK 620 2 CYS A 384 SG 106.2 REMARK 620 3 HIS A 397 NE2 93.9 79.1 REMARK 620 4 HIS A 401 NE2 109.7 140.7 113.4 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 503 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 409 SG REMARK 620 2 CYS A 412 SG 89.4 REMARK 620 3 HIS A 425 NE2 105.0 87.8 REMARK 620 4 HIS A 430 NE2 127.1 121.5 116.9 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 504 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 439 SG REMARK 620 2 CYS A 442 SG 104.0 REMARK 620 3 HIS A 455 NE2 114.6 122.1 REMARK 620 4 HIS A 460 NE2 115.2 78.3 117.3 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 501 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 502 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 503 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 504 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5K5L RELATED DB: PDB REMARK 900 RELATED ID: 5K5J RELATED DB: PDB REMARK 900 RELATED ID: 5K5I RELATED DB: PDB DBREF 5K5H A 348 464 UNP P49711 CTCF_HUMAN 348 464 DBREF 5K5H B 1 13 PDB 5K5H 5K5H 1 13 DBREF 5K5H C 3 15 PDB 5K5H 5K5H 3 15 SEQADV 5K5H GLY A 343 UNP P49711 EXPRESSION TAG SEQADV 5K5H PRO A 344 UNP P49711 EXPRESSION TAG SEQADV 5K5H LEU A 345 UNP P49711 EXPRESSION TAG SEQADV 5K5H GLY A 346 UNP P49711 EXPRESSION TAG SEQADV 5K5H SER A 347 UNP P49711 EXPRESSION TAG SEQRES 1 A 122 GLY PRO LEU GLY SER GLU LYS PRO PHE LYS CYS SER MET SEQRES 2 A 122 CYS ASP TYR ALA SER VAL GLU VAL SER LYS LEU LYS ARG SEQRES 3 A 122 HIS ILE ARG SER HIS THR GLY GLU ARG PRO PHE GLN CYS SEQRES 4 A 122 SER LEU CYS SER TYR ALA SER ARG ASP THR TYR LYS LEU SEQRES 5 A 122 LYS ARG HIS MET ARG THR HIS SER GLY GLU LYS PRO TYR SEQRES 6 A 122 GLU CYS TYR ILE CYS HIS ALA ARG PHE THR GLN SER GLY SEQRES 7 A 122 THR MET LYS MET HIS ILE LEU GLN LYS HIS THR GLU ASN SEQRES 8 A 122 VAL ALA LYS PHE HIS CYS PRO HIS CYS ASP THR VAL ILE SEQRES 9 A 122 ALA ARG LYS SER ASP LEU GLY VAL HIS LEU ARG LYS GLN SEQRES 10 A 122 HIS SER TYR ILE GLU SEQRES 1 B 13 DC DA DG DC DA DG DG DG DG DG DC DG DC SEQRES 1 C 13 DC DG DC DC DC DC DC DT DG DC DT DG DG HET ZN A 501 1 HET ZN A 502 1 HET ZN A 503 1 HET ZN A 504 1 HETNAM ZN ZINC ION FORMUL 4 ZN 4(ZN 2+) FORMUL 8 HOH *6(H2 O) HELIX 1 AA1 VAL A 363 GLY A 375 1 13 HELIX 2 AA2 ASP A 390 ARG A 399 1 10 HELIX 3 AA3 GLN A 418 HIS A 430 1 13 HELIX 4 AA4 ARG A 448 HIS A 460 1 13 SHEET 1 AA1 2 TYR A 407 GLU A 408 0 SHEET 2 AA1 2 ARG A 415 PHE A 416 -1 O PHE A 416 N TYR A 407 SHEET 1 AA2 2 PHE A 437 HIS A 438 0 SHEET 2 AA2 2 VAL A 445 ILE A 446 -1 O ILE A 446 N PHE A 437 LINK SG CYS A 353 ZN ZN A 501 1555 1555 2.34 LINK SG CYS A 356 ZN ZN A 501 1555 1555 2.28 LINK NE2 HIS A 369 ZN ZN A 501 1555 1555 2.03 LINK NE2 HIS A 373 ZN ZN A 501 1555 1555 2.04 LINK SG CYS A 381 ZN ZN A 502 1555 1555 2.29 LINK SG CYS A 384 ZN ZN A 502 1555 1555 2.33 LINK NE2 HIS A 397 ZN ZN A 502 1555 1555 2.05 LINK NE2 HIS A 401 ZN ZN A 502 1555 1555 2.01 LINK SG CYS A 409 ZN ZN A 503 1555 1555 2.32 LINK SG CYS A 412 ZN ZN A 503 1555 1555 2.32 LINK NE2 HIS A 425 ZN ZN A 503 1555 1555 2.03 LINK NE2 HIS A 430 ZN ZN A 503 1555 1555 2.02 LINK SG CYS A 439 ZN ZN A 504 1555 1555 2.33 LINK SG CYS A 442 ZN ZN A 504 1555 1555 2.33 LINK NE2 HIS A 455 ZN ZN A 504 1555 1555 2.04 LINK NE2 HIS A 460 ZN ZN A 504 1555 1555 2.04 SITE 1 AC1 5 CYS A 353 MET A 355 CYS A 356 HIS A 369 SITE 2 AC1 5 HIS A 373 SITE 1 AC2 4 CYS A 381 CYS A 384 HIS A 397 HIS A 401 SITE 1 AC3 4 CYS A 409 CYS A 412 HIS A 425 HIS A 430 SITE 1 AC4 4 CYS A 439 CYS A 442 HIS A 455 HIS A 460 CRYST1 52.800 52.800 166.170 90.00 90.00 90.00 P 41 21 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.018939 0.000000 0.000000 0.00000 SCALE2 0.000000 0.018939 0.000000 0.00000 SCALE3 0.000000 0.000000 0.006018 0.00000 ATOM 1 N PRO A 350 -28.639 21.897 9.748 1.00 62.76 N ANISOU 1 N PRO A 350 11604 4618 7622 1345 -873 298 N ATOM 2 CA PRO A 350 -27.558 20.944 9.469 1.00 60.12 C ANISOU 2 CA PRO A 350 11323 4417 7104 1349 -956 216 C ATOM 3 C PRO A 350 -26.245 21.643 9.124 1.00 59.33 C ANISOU 3 C PRO A 350 11826 3951 6765 934 -1206 50 C ATOM 4 O PRO A 350 -26.059 22.809 9.472 1.00 54.64 O ANISOU 4 O PRO A 350 11610 3040 6113 674 -1288 -83 O ATOM 5 CB PRO A 350 -28.087 20.156 8.266 1.00 57.83 C ANISOU 5 CB PRO A 350 10631 4340 7002 1270 -844 423 C ATOM 6 CG PRO A 350 -29.571 20.310 8.328 1.00 52.13 C ANISOU 6 CG PRO A 350 9506 3698 6603 1357 -680 554 C ATOM 7 CD PRO A 350 -29.806 21.684 8.875 1.00 55.13 C ANISOU 7 CD PRO A 350 10206 3783 6957 1320 -739 518 C ATOM 8 N PHE A 351 -25.345 20.931 8.455 1.00 66.68 N ANISOU 8 N PHE A 351 12671 5086 7577 731 -1256 11 N ATOM 9 CA PHE A 351 -24.120 21.526 7.947 1.00 79.79 C ANISOU 9 CA PHE A 351 14271 6999 9048 12 -1316 -203 C ATOM 10 C PHE A 351 -24.329 22.029 6.523 1.00 88.11 C ANISOU 10 C PHE A 351 15566 7722 10188 -455 -1304 67 C ATOM 11 O PHE A 351 -25.230 21.588 5.806 1.00 80.42 O ANISOU 11 O PHE A 351 14640 6542 9373 -209 -1278 395 O ATOM 12 CB PHE A 351 -22.967 20.523 7.982 1.00 85.92 C ANISOU 12 CB PHE A 351 14465 8571 9610 -29 -1275 -411 C ATOM 13 CG PHE A 351 -22.504 20.178 9.366 1.00 96.71 C ANISOU 13 CG PHE A 351 15608 10345 10793 369 -1314 -726 C ATOM 14 CD1 PHE A 351 -23.050 19.103 10.048 1.00 93.49 C ANISOU 14 CD1 PHE A 351 15050 10068 10403 1119 -1208 -630 C ATOM 15 CD2 PHE A 351 -21.519 20.929 9.986 1.00103.64 C ANISOU 15 CD2 PHE A 351 16437 11477 11463 -8 -1444 -1135 C ATOM 16 CE1 PHE A 351 -22.622 18.784 11.322 1.00 95.10 C ANISOU 16 CE1 PHE A 351 15098 10650 10387 1548 -1234 -900 C ATOM 17 CE2 PHE A 351 -21.087 20.615 11.259 1.00104.68 C ANISOU 17 CE2 PHE A 351 16363 12035 11377 397 -1518 -1443 C ATOM 18 CZ PHE A 351 -21.640 19.543 11.928 1.00 99.16 C ANISOU 18 CZ PHE A 351 15554 11461 10661 1207 -1415 -1308 C ATOM 19 N LYS A 352 -23.474 22.964 6.118 1.00 98.67 N ANISOU 19 N LYS A 352 17062 9021 11407 -1139 -1314 -92 N ATOM 20 CA LYS A 352 -23.551 23.568 4.798 1.00 99.69 C ANISOU 20 CA LYS A 352 17504 8812 11564 -1610 -1268 153 C ATOM 21 C LYS A 352 -22.172 23.585 4.153 1.00101.22 C ANISOU 21 C LYS A 352 17425 9458 11577 -2293 -1186 -44 C ATOM 22 O LYS A 352 -21.146 23.409 4.816 1.00 99.47 O ANISOU 22 O LYS A 352 16819 9757 11219 -2470 -1196 -416 O ATOM 23 CB LYS A 352 -24.115 24.996 4.857 1.00 98.59 C ANISOU 23 CB LYS A 352 17772 8203 11483 -1681 -1225 221 C ATOM 24 CG LYS A 352 -25.618 25.078 5.091 1.00 94.88 C ANISOU 24 CG LYS A 352 17151 7698 11202 -983 -1192 447 C ATOM 25 CD LYS A 352 -25.967 25.148 6.570 1.00 89.41 C ANISOU 25 CD LYS A 352 16477 6942 10554 -589 -1224 277 C ATOM 26 CE LYS A 352 -27.458 25.390 6.766 1.00 81.59 C ANISOU 26 CE LYS A 352 15229 5997 9775 -74 -1120 461 C ATOM 27 NZ LYS A 352 -27.818 25.557 8.201 1.00 77.97 N ANISOU 27 NZ LYS A 352 14776 5503 9344 261 -1103 319 N ATOM 28 N CYS A 353 -22.166 23.798 2.839 1.00103.18 N ANISOU 28 N CYS A 353 17867 9525 11812 -2653 -1102 209 N ATOM 29 CA CYS A 353 -20.945 23.911 2.052 1.00108.22 C ANISOU 29 CA CYS A 353 18323 10497 12298 -3338 -967 81 C ATOM 30 C CYS A 353 -20.913 25.288 1.408 1.00111.26 C ANISOU 30 C CYS A 353 19192 10409 12672 -3786 -835 169 C ATOM 31 O CYS A 353 -21.850 25.665 0.696 1.00110.71 O ANISOU 31 O CYS A 353 19321 10092 12653 -3425 -807 493 O ATOM 32 CB CYS A 353 -20.870 22.815 0.987 1.00109.91 C ANISOU 32 CB CYS A 353 18221 11079 12459 -3248 -902 311 C ATOM 33 SG CYS A 353 -19.514 23.006 -0.196 1.00108.40 S ANISOU 33 SG CYS A 353 17897 11202 12088 -4070 -682 242 S ATOM 34 N SER A 354 -19.841 26.035 1.658 1.00121.53 N ANISOU 34 N SER A 354 20460 11818 13899 -4400 -721 -165 N ATOM 35 CA SER A 354 -19.678 27.368 1.094 1.00137.73 C ANISOU 35 CA SER A 354 22831 13565 15936 -4708 -512 -111 C ATOM 36 C SER A 354 -19.117 27.349 -0.324 1.00149.98 C ANISOU 36 C SER A 354 24336 15267 17383 -5053 -307 56 C ATOM 37 O SER A 354 -18.731 28.406 -0.834 1.00156.08 O ANISOU 37 O SER A 354 25357 15828 18117 -5402 -93 42 O ATOM 38 CB SER A 354 -18.778 28.214 2.001 1.00137.02 C ANISOU 38 CB SER A 354 22707 13515 15840 -5202 -448 -564 C ATOM 39 OG SER A 354 -17.546 27.561 2.251 1.00130.85 O ANISOU 39 OG SER A 354 21369 13374 14976 -5649 -461 -946 O ATOM 40 N MET A 355 -19.066 26.183 -0.969 1.00145.32 N ANISOU 40 N MET A 355 23466 15014 16737 -4951 -346 208 N ATOM 41 CA MET A 355 -18.530 26.054 -2.318 1.00137.94 C ANISOU 41 CA MET A 355 22477 14254 15679 -5228 -153 358 C ATOM 42 C MET A 355 -19.612 25.714 -3.335 1.00118.45 C ANISOU 42 C MET A 355 20193 11615 13196 -4701 -229 755 C ATOM 43 O MET A 355 -19.777 26.428 -4.328 1.00121.32 O ANISOU 43 O MET A 355 20851 11750 13494 -4730 -108 919 O ATOM 44 CB MET A 355 -17.423 24.990 -2.342 1.00141.84 C ANISOU 44 CB MET A 355 22416 15390 16089 -5594 -97 155 C ATOM 45 CG MET A 355 -16.307 25.228 -1.339 1.00150.26 C ANISOU 45 CG MET A 355 23105 16827 17161 -6074 -69 -338 C ATOM 46 SD MET A 355 -15.394 26.747 -1.665 1.00162.68 S ANISOU 46 SD MET A 355 24861 18222 18729 -6692 232 -532 S ATOM 47 CE MET A 355 -14.754 26.410 -3.303 1.00164.19 C ANISOU 47 CE MET A 355 24967 18635 18781 -6947 513 -310 C ATOM 48 N CYS A 356 -20.360 24.633 -3.112 1.00114.45 N ANISOU 48 N CYS A 356 19496 11237 12754 -4213 -428 880 N ATOM 49 CA CYS A 356 -21.396 24.195 -4.039 1.00101.59 C ANISOU 49 CA CYS A 356 17900 9560 11139 -3709 -523 1169 C ATOM 50 C CYS A 356 -22.773 24.132 -3.391 1.00 81.32 C ANISOU 50 C CYS A 356 15340 6797 8761 -3051 -726 1254 C ATOM 51 O CYS A 356 -23.699 23.567 -3.986 1.00 63.99 O ANISOU 51 O CYS A 356 13014 4670 6630 -2617 -823 1415 O ATOM 52 CB CYS A 356 -21.039 22.828 -4.630 1.00101.91 C ANISOU 52 CB CYS A 356 17601 10026 11094 -3722 -511 1229 C ATOM 53 SG CYS A 356 -20.999 21.490 -3.417 1.00 98.72 S ANISOU 53 SG CYS A 356 16837 9904 10768 -3527 -623 1133 S ATOM 54 N ASP A 357 -22.929 24.692 -2.190 1.00 97.25 N ANISOU 54 N ASP A 357 17462 8609 10881 -2978 -773 1114 N ATOM 55 CA ASP A 357 -24.203 24.699 -1.468 1.00104.63 C ANISOU 55 CA ASP A 357 18347 9399 12007 -2354 -912 1166 C ATOM 56 C ASP A 357 -24.720 23.278 -1.242 1.00101.29 C ANISOU 56 C ASP A 357 17535 9260 11692 -1926 -1016 1205 C ATOM 57 O ASP A 357 -25.891 22.970 -1.475 1.00 99.57 O ANISOU 57 O ASP A 357 17119 9085 11629 -1443 -1069 1315 O ATOM 58 CB ASP A 357 -25.242 25.560 -2.193 1.00113.73 C ANISOU 58 CB ASP A 357 19675 10324 13214 -2072 -905 1348 C ATOM 59 CG ASP A 357 -24.869 27.031 -2.207 1.00119.83 C ANISOU 59 CG ASP A 357 20886 10741 13904 -2397 -771 1315 C ATOM 60 OD1 ASP A 357 -24.262 27.500 -1.223 1.00122.30 O ANISOU 60 OD1 ASP A 357 21324 10932 14213 -2656 -725 1113 O ATOM 61 OD2 ASP A 357 -25.179 27.718 -3.202 1.00120.56 O ANISOU 61 OD2 ASP A 357 21214 10663 13931 -2397 -702 1478 O ATOM 62 N TYR A 358 -23.825 22.407 -0.782 1.00 98.12 N ANISOU 62 N TYR A 358 17001 9068 11214 -2146 -1013 1096 N ATOM 63 CA TYR A 358 -24.168 21.041 -0.407 1.00 84.47 C ANISOU 63 CA TYR A 358 14958 7570 9565 -1738 -1064 1126 C ATOM 64 C TYR A 358 -24.427 20.981 1.092 1.00 83.87 C ANISOU 64 C TYR A 358 14888 7376 9602 -1393 -1132 983 C ATOM 65 O TYR A 358 -23.644 21.516 1.883 1.00 80.60 O ANISOU 65 O TYR A 358 14569 6948 9108 -1669 -1137 744 O ATOM 66 CB TYR A 358 -23.050 20.071 -0.790 1.00 88.31 C ANISOU 66 CB TYR A 358 15207 8475 9872 -2070 -969 1086 C ATOM 67 CG TYR A 358 -23.113 18.743 -0.064 1.00101.94 C ANISOU 67 CG TYR A 358 16442 10640 11651 -1557 -933 972 C ATOM 68 CD1 TYR A 358 -24.006 17.755 -0.458 1.00106.24 C ANISOU 68 CD1 TYR A 358 16887 11178 12302 -1138 -930 1161 C ATOM 69 CD2 TYR A 358 -22.274 18.477 1.012 1.00103.72 C ANISOU 69 CD2 TYR A 358 16319 11288 11803 -1487 -887 663 C ATOM 70 CE1 TYR A 358 -24.065 16.541 0.203 1.00 93.28 C ANISOU 70 CE1 TYR A 358 14862 9871 10709 -679 -826 1064 C ATOM 71 CE2 TYR A 358 -22.326 17.266 1.677 1.00 86.32 C ANISOU 71 CE2 TYR A 358 13734 9454 9609 -962 -813 589 C ATOM 72 CZ TYR A 358 -23.223 16.303 1.268 1.00 79.19 C ANISOU 72 CZ TYR A 358 12790 8469 8828 -568 -755 800 C ATOM 73 OH TYR A 358 -23.278 15.097 1.928 1.00 73.24 O ANISOU 73 OH TYR A 358 11721 8021 8087 -55 -614 733 O ATOM 74 N ALA A 359 -25.518 20.326 1.478 1.00 84.71 N ANISOU 74 N ALA A 359 14687 7590 9907 -767 -1126 1021 N ATOM 75 CA ALA A 359 -25.911 20.215 2.875 1.00 89.93 C ANISOU 75 CA ALA A 359 15274 8212 10683 -336 -1130 888 C ATOM 76 C ALA A 359 -25.890 18.756 3.309 1.00 82.14 C ANISOU 76 C ALA A 359 13975 7515 9720 65 -1057 871 C ATOM 77 O ALA A 359 -26.219 17.858 2.527 1.00 70.41 O ANISOU 77 O ALA A 359 12195 6259 8298 154 -967 973 O ATOM 78 CB ALA A 359 -27.303 20.810 3.109 1.00 96.92 C ANISOU 78 CB ALA A 359 15964 9053 11809 8 -1066 923 C ATOM 79 N SER A 360 -25.499 18.529 4.561 1.00 85.66 N ANISOU 79 N SER A 360 14426 8019 10101 339 -1059 694 N ATOM 80 CA SER A 360 -25.479 17.195 5.141 1.00 82.59 C ANISOU 80 CA SER A 360 13659 8013 9709 831 -905 633 C ATOM 81 C SER A 360 -25.600 17.322 6.651 1.00 65.42 C ANISOU 81 C SER A 360 11525 5803 7529 1270 -895 455 C ATOM 82 O SER A 360 -25.114 18.287 7.246 1.00 57.14 O ANISOU 82 O SER A 360 10643 4700 6368 1057 -1013 256 O ATOM 83 CB SER A 360 -24.202 16.431 4.771 1.00 96.86 C ANISOU 83 CB SER A 360 15067 10463 11272 607 -807 489 C ATOM 84 OG SER A 360 -23.054 17.062 5.312 1.00111.13 O ANISOU 84 OG SER A 360 16786 12575 12864 298 -883 199 O ATOM 85 N VAL A 361 -26.258 16.336 7.265 1.00 68.17 N ANISOU 85 N VAL A 361 11421 6468 8013 1663 -648 434 N ATOM 86 CA VAL A 361 -26.482 16.371 8.709 1.00 72.95 C ANISOU 86 CA VAL A 361 11925 7195 8598 1964 -563 281 C ATOM 87 C VAL A 361 -25.314 15.822 9.509 1.00 75.95 C ANISOU 87 C VAL A 361 12369 7847 8642 2380 -588 88 C ATOM 88 O VAL A 361 -25.339 15.888 10.745 1.00 76.49 O ANISOU 88 O VAL A 361 12399 8056 8609 2627 -549 -55 O ATOM 89 CB VAL A 361 -27.756 15.589 9.078 1.00 72.81 C ANISOU 89 CB VAL A 361 11389 7397 8879 1969 -303 353 C ATOM 90 CG1 VAL A 361 -28.936 16.090 8.260 1.00 72.83 C ANISOU 90 CG1 VAL A 361 11250 7214 9207 1708 -327 501 C ATOM 91 CG2 VAL A 361 -27.547 14.096 8.868 1.00 60.46 C ANISOU 91 CG2 VAL A 361 9541 6155 7276 2055 -113 360 C ATOM 92 N GLU A 362 -24.290 15.289 8.849 1.00 80.05 N ANISOU 92 N GLU A 362 12719 8732 8967 2264 -603 43 N ATOM 93 CA GLU A 362 -23.162 14.664 9.521 1.00 75.77 C ANISOU 93 CA GLU A 362 11842 8847 8099 2479 -554 -197 C ATOM 94 C GLU A 362 -21.890 15.474 9.308 1.00 62.98 C ANISOU 94 C GLU A 362 10059 7620 6252 1864 -767 -473 C ATOM 95 O GLU A 362 -21.765 16.244 8.352 1.00 63.35 O ANISOU 95 O GLU A 362 10213 7472 6384 1227 -867 -426 O ATOM 96 CB GLU A 362 -22.958 13.229 9.022 1.00 79.76 C ANISOU 96 CB GLU A 362 12052 9700 8554 2744 -292 -72 C ATOM 97 CG GLU A 362 -24.180 12.333 9.178 1.00 83.88 C ANISOU 97 CG GLU A 362 12523 10020 9326 2871 -3 128 C ATOM 98 CD GLU A 362 -24.292 11.714 10.561 1.00 94.38 C ANISOU 98 CD GLU A 362 13708 11623 10528 3010 138 85 C ATOM 99 OE1 GLU A 362 -24.897 10.627 10.675 1.00 96.38 O ANISOU 99 OE1 GLU A 362 13795 11940 10883 2850 354 214 O ATOM 100 OE2 GLU A 362 -23.775 12.306 11.533 1.00 99.92 O ANISOU 100 OE2 GLU A 362 14516 12438 11011 3274 -16 -79 O ATOM 101 N VAL A 363 -20.939 15.287 10.223 1.00 63.12 N ANISOU 101 N VAL A 363 9810 8208 5964 2072 -822 -771 N ATOM 102 CA VAL A 363 -19.657 15.975 10.114 1.00 71.05 C ANISOU 102 CA VAL A 363 10560 9686 6751 1489 -1013 -1099 C ATOM 103 C VAL A 363 -18.709 15.204 9.205 1.00 68.54 C ANISOU 103 C VAL A 363 9794 9948 6300 1275 -902 -1086 C ATOM 104 O VAL A 363 -17.980 15.799 8.403 1.00 62.39 O ANISOU 104 O VAL A 363 8887 9315 5505 576 -971 -1187 O ATOM 105 CB VAL A 363 -19.049 16.191 11.511 1.00 84.78 C ANISOU 105 CB VAL A 363 12174 11839 8200 1794 -1173 -1476 C ATOM 106 CG1 VAL A 363 -18.035 17.328 11.480 1.00 85.78 C ANISOU 106 CG1 VAL A 363 12170 12219 8203 1048 -1412 -1863 C ATOM 107 CG2 VAL A 363 -20.142 16.455 12.535 1.00 92.32 C ANISOU 107 CG2 VAL A 363 13570 12253 9255 2313 -1172 -1410 C ATOM 108 N SER A 364 -18.697 13.873 9.320 1.00 71.98 N ANISOU 108 N SER A 364 10016 10700 6635 1878 -688 -959 N ATOM 109 CA SER A 364 -17.831 13.063 8.469 1.00 79.73 C ANISOU 109 CA SER A 364 10601 12215 7477 1750 -542 -927 C ATOM 110 C SER A 364 -18.224 13.189 7.003 1.00 73.89 C ANISOU 110 C SER A 364 10018 11087 6970 1214 -459 -664 C ATOM 111 O SER A 364 -17.358 13.312 6.128 1.00 58.00 O ANISOU 111 O SER A 364 7768 9397 4872 694 -449 -720 O ATOM 112 CB SER A 364 -17.873 11.601 8.917 1.00 83.87 C ANISOU 112 CB SER A 364 10976 13040 7851 2566 -275 -813 C ATOM 113 OG SER A 364 -19.200 11.099 8.919 1.00 77.37 O ANISOU 113 OG SER A 364 10517 11591 7287 2952 -76 -518 O ATOM 114 N LYS A 365 -19.527 13.166 6.714 1.00 78.76 N ANISOU 114 N LYS A 365 11024 11032 7870 1344 -398 -384 N ATOM 115 CA LYS A 365 -19.992 13.340 5.344 1.00 69.18 C ANISOU 115 CA LYS A 365 9992 9447 6845 883 -366 -141 C ATOM 116 C LYS A 365 -19.758 14.754 4.833 1.00 69.55 C ANISOU 116 C LYS A 365 10238 9247 6940 154 -569 -207 C ATOM 117 O LYS A 365 -19.794 14.974 3.618 1.00 71.14 O ANISOU 117 O LYS A 365 10553 9278 7200 -301 -543 -43 O ATOM 118 CB LYS A 365 -21.473 12.975 5.244 1.00 39.64 C ANISOU 118 CB LYS A 365 6564 5107 3389 1240 -281 133 C ATOM 119 CG LYS A 365 -21.755 11.521 5.590 1.00 45.39 C ANISOU 119 CG LYS A 365 7148 5995 4103 1888 6 215 C ATOM 120 CD LYS A 365 -23.241 11.248 5.729 1.00 39.65 C ANISOU 120 CD LYS A 365 6694 4681 3691 2236 102 417 C ATOM 121 CE LYS A 365 -23.486 9.831 6.222 1.00 38.65 C ANISOU 121 CE LYS A 365 6419 4714 3552 2737 449 441 C ATOM 122 NZ LYS A 365 -24.925 9.584 6.511 1.00 39.62 N ANISOU 122 NZ LYS A 365 6498 4563 3995 2425 518 469 N ATOM 123 N LEU A 366 -19.518 15.715 5.728 1.00 68.36 N ANISOU 123 N LEU A 366 10173 9055 6747 37 -746 -448 N ATOM 124 CA LEU A 366 -19.109 17.044 5.288 1.00 70.45 C ANISOU 124 CA LEU A 366 10624 9116 7027 -703 -876 -561 C ATOM 125 C LEU A 366 -17.662 17.039 4.814 1.00 70.94 C ANISOU 125 C LEU A 366 10262 9811 6881 -1217 -833 -787 C ATOM 126 O LEU A 366 -17.340 17.642 3.783 1.00 64.54 O ANISOU 126 O LEU A 366 9563 8858 6100 -1856 -789 -727 O ATOM 127 CB LEU A 366 -19.305 18.058 6.415 1.00 80.70 C ANISOU 127 CB LEU A 366 12171 10148 8342 -689 -1051 -784 C ATOM 128 CG LEU A 366 -18.860 19.490 6.113 1.00 99.81 C ANISOU 128 CG LEU A 366 14841 12306 10776 -1464 -1143 -950 C ATOM 129 CD1 LEU A 366 -19.605 20.050 4.909 1.00 98.20 C ANISOU 129 CD1 LEU A 366 15098 11456 10758 -1797 -1085 -599 C ATOM 130 CD2 LEU A 366 -19.059 20.376 7.332 1.00113.51 C ANISOU 130 CD2 LEU A 366 16831 13793 12504 -1386 -1297 -1206 C ATOM 131 N LYS A 367 -16.775 16.362 5.552 1.00 72.91 N ANISOU 131 N LYS A 367 10020 10775 6906 -919 -829 -1044 N ATOM 132 CA LYS A 367 -15.388 16.238 5.113 1.00 70.61 C ANISOU 132 CA LYS A 367 9232 11177 6421 -1340 -774 -1265 C ATOM 133 C LYS A 367 -15.270 15.396 3.849 1.00 71.67 C ANISOU 133 C LYS A 367 9255 11424 6552 -1404 -544 -989 C ATOM 134 O LYS A 367 -14.366 15.627 3.037 1.00 79.40 O ANISOU 134 O LYS A 367 10013 12695 7460 -1975 -457 -1065 O ATOM 135 CB LYS A 367 -14.528 15.635 6.225 1.00 65.38 C ANISOU 135 CB LYS A 367 8049 11304 5487 -882 -842 -1589 C ATOM 136 CG LYS A 367 -14.247 16.576 7.385 1.00 73.89 C ANISOU 136 CG LYS A 367 9125 12463 6486 -994 -1097 -1984 C ATOM 137 CD LYS A 367 -13.190 15.997 8.317 1.00 79.52 C ANISOU 137 CD LYS A 367 9237 14109 6867 -605 -1194 -2342 C ATOM 138 CE LYS A 367 -12.843 16.966 9.439 1.00 77.40 C ANISOU 138 CE LYS A 367 8943 13978 6487 -776 -1479 -2798 C ATOM 139 NZ LYS A 367 -11.739 16.456 10.300 1.00 77.81 N ANISOU 139 NZ LYS A 367 8356 15033 6174 -417 -1623 -3185 N ATOM 140 N ARG A 368 -16.159 14.415 3.668 1.00 61.08 N ANISOU 140 N ARG A 368 8065 9855 5288 -846 -420 -688 N ATOM 141 CA ARG A 368 -16.157 13.646 2.429 1.00 61.09 C ANISOU 141 CA ARG A 368 8036 9888 5286 -926 -207 -436 C ATOM 142 C ARG A 368 -16.488 14.522 1.230 1.00 55.20 C ANISOU 142 C ARG A 368 7668 8632 4675 -1581 -225 -253 C ATOM 143 O ARG A 368 -15.975 14.290 0.130 1.00 54.94 O ANISOU 143 O ARG A 368 7548 8767 4561 -1926 -72 -160 O ATOM 144 CB ARG A 368 -17.148 12.485 2.515 1.00 71.93 C ANISOU 144 CB ARG A 368 9541 11045 6743 -245 -66 -190 C ATOM 145 CG ARG A 368 -16.793 11.426 3.539 1.00 82.12 C ANISOU 145 CG ARG A 368 10516 12829 7858 468 52 -306 C ATOM 146 CD ARG A 368 -17.324 10.068 3.110 1.00 73.97 C ANISOU 146 CD ARG A 368 9532 11724 6851 938 339 -67 C ATOM 147 NE ARG A 368 -18.701 10.146 2.631 1.00 59.82 N ANISOU 147 NE ARG A 368 8162 9218 5349 917 332 177 N ATOM 148 CZ ARG A 368 -19.371 9.120 2.118 1.00 57.42 C ANISOU 148 CZ ARG A 368 7960 8721 5134 1186 559 368 C ATOM 149 NH1 ARG A 368 -20.622 9.281 1.706 1.00 56.25 N ANISOU 149 NH1 ARG A 368 8137 7979 5256 1135 506 544 N ATOM 150 NH2 ARG A 368 -18.791 7.933 2.014 1.00 57.53 N ANISOU 150 NH2 ARG A 368 7751 9145 4963 1510 847 367 N ATOM 151 N HIS A 369 -17.347 15.525 1.418 1.00 52.27 N ANISOU 151 N HIS A 369 7748 7628 4484 -1719 -390 -186 N ATOM 152 CA HIS A 369 -17.646 16.447 0.330 1.00 61.00 C ANISOU 152 CA HIS A 369 9270 8233 5676 -2291 -403 -2 C ATOM 153 C HIS A 369 -16.456 17.343 0.015 1.00 79.19 C ANISOU 153 C HIS A 369 11459 10759 7869 -3030 -356 -224 C ATOM 154 O HIS A 369 -16.309 17.798 -1.125 1.00 86.58 O ANISOU 154 O HIS A 369 12625 11481 8790 -3534 -248 -70 O ATOM 155 CB HIS A 369 -18.870 17.292 0.681 1.00 52.67 C ANISOU 155 CB HIS A 369 8734 6452 4824 -2171 -573 132 C ATOM 156 CG HIS A 369 -19.242 18.280 -0.379 1.00 69.21 C ANISOU 156 CG HIS A 369 11321 8002 6974 -2661 -586 347 C ATOM 157 ND1 HIS A 369 -19.946 17.927 -1.510 1.00 68.26 N ANISOU 157 ND1 HIS A 369 11426 7630 6880 -2605 -554 670 N ATOM 158 CD2 HIS A 369 -19.002 19.608 -0.484 1.00 73.48 C ANISOU 158 CD2 HIS A 369 12203 8195 7521 -3199 -611 282 C ATOM 159 CE1 HIS A 369 -20.127 18.996 -2.264 1.00 71.17 C ANISOU 159 CE1 HIS A 369 12261 7537 7245 -3035 -573 820 C ATOM 160 NE2 HIS A 369 -19.564 20.030 -1.663 1.00 77.14 N ANISOU 160 NE2 HIS A 369 13116 8195 7998 -3406 -580 600 N ATOM 161 N ILE A 370 -15.598 17.601 1.006 1.00 74.37 N ANISOU 161 N ILE A 370 10495 10587 7174 -3108 -424 -598 N ATOM 162 CA ILE A 370 -14.421 18.430 0.782 1.00 77.68 C ANISOU 162 CA ILE A 370 10727 11272 7515 -3856 -362 -877 C ATOM 163 C ILE A 370 -13.374 17.696 -0.047 1.00 86.81 C ANISOU 163 C ILE A 370 11413 13055 8516 -4060 -142 -892 C ATOM 164 O ILE A 370 -12.561 18.336 -0.724 1.00 86.83 O ANISOU 164 O ILE A 370 11362 13142 8490 -4764 4 -993 O ATOM 165 CB ILE A 370 -13.847 18.895 2.135 1.00 80.69 C ANISOU 165 CB ILE A 370 10827 11992 7841 -3863 -537 -1325 C ATOM 166 CG1 ILE A 370 -14.951 19.522 2.988 1.00 80.52 C ANISOU 166 CG1 ILE A 370 11303 11333 7959 -3568 -727 -1288 C ATOM 167 CG2 ILE A 370 -12.728 19.903 1.939 1.00 87.65 C ANISOU 167 CG2 ILE A 370 11547 13066 8691 -4732 -472 -1664 C ATOM 168 CD1 ILE A 370 -15.658 20.684 2.319 1.00 80.55 C ANISOU 168 CD1 ILE A 370 11991 10487 8128 -4021 -698 -1074 C ATOM 169 N ARG A 371 -13.383 16.360 -0.024 1.00105.42 N ANISOU 169 N ARG A 371 13457 15824 10773 -3458 -73 -787 N ATOM 170 CA ARG A 371 -12.471 15.598 -0.870 1.00114.64 C ANISOU 170 CA ARG A 371 14230 17542 11784 -3583 167 -760 C ATOM 171 C ARG A 371 -12.737 15.852 -2.348 1.00112.41 C ANISOU 171 C ARG A 371 14353 16821 11538 -4031 342 -449 C ATOM 172 O ARG A 371 -11.820 15.751 -3.172 1.00118.72 O ANISOU 172 O ARG A 371 14918 17967 12222 -4437 565 -473 O ATOM 173 CB ARG A 371 -12.594 14.105 -0.565 1.00123.24 C ANISOU 173 CB ARG A 371 15038 19026 12760 -2788 243 -666 C ATOM 174 CG ARG A 371 -12.513 13.752 0.911 1.00134.96 C ANISOU 174 CG ARG A 371 16230 20877 14172 -2190 84 -904 C ATOM 175 CD ARG A 371 -12.970 12.320 1.149 1.00143.55 C ANISOU 175 CD ARG A 371 17261 22095 15185 -1358 216 -718 C ATOM 176 NE ARG A 371 -13.009 11.975 2.567 1.00151.55 N ANISOU 176 NE ARG A 371 18098 23378 16106 -711 94 -896 N ATOM 177 CZ ARG A 371 -12.060 11.290 3.197 1.00156.37 C ANISOU 177 CZ ARG A 371 18191 24767 16457 -303 139 -1101 C ATOM 178 NH1 ARG A 371 -10.991 10.869 2.534 1.00158.48 N ANISOU 178 NH1 ARG A 371 18025 25630 16558 -488 312 -1158 N ATOM 179 NH2 ARG A 371 -12.181 11.022 4.490 1.00155.60 N ANISOU 179 NH2 ARG A 371 18014 24863 16245 329 21 -1240 N ATOM 180 N SER A 372 -13.980 16.183 -2.703 1.00136.28 N ANISOU 180 N SER A 372 11180 16606 23994 -2927 1680 -998 N ATOM 181 CA SER A 372 -14.340 16.460 -4.087 1.00130.77 C ANISOU 181 CA SER A 372 10184 16236 23267 -2722 1614 -963 C ATOM 182 C SER A 372 -13.976 17.872 -4.524 1.00122.40 C ANISOU 182 C SER A 372 9017 15301 22190 -2406 1985 -784 C ATOM 183 O SER A 372 -14.053 18.170 -5.721 1.00128.03 O ANISOU 183 O SER A 372 9564 16290 22790 -2088 1992 -710 O ATOM 184 CB SER A 372 -15.839 16.229 -4.296 1.00136.53 C ANISOU 184 CB SER A 372 10646 17163 24067 -2835 1548 -896 C ATOM 185 OG SER A 372 -16.609 17.061 -3.445 1.00133.40 O ANISOU 185 OG SER A 372 10333 16756 23595 -2863 1844 -641 O ATOM 186 N HIS A 373 -13.593 18.743 -3.593 1.00119.95 N ANISOU 186 N HIS A 373 8941 14800 21835 -2385 2265 -709 N ATOM 187 CA HIS A 373 -13.139 20.092 -3.909 1.00117.40 C ANISOU 187 CA HIS A 373 8623 14468 21514 -2100 2655 -574 C ATOM 188 C HIS A 373 -11.640 20.271 -3.744 1.00114.37 C ANISOU 188 C HIS A 373 8386 13843 21228 -2036 2732 -823 C ATOM 189 O HIS A 373 -10.999 20.880 -4.603 1.00 95.91 O ANISOU 189 O HIS A 373 5986 11492 18963 -1791 2984 -776 O ATOM 190 CB HIS A 373 -13.870 21.116 -3.033 1.00 96.45 C ANISOU 190 CB HIS A 373 6078 11774 18793 -2096 2910 -388 C ATOM 191 CG HIS A 373 -15.345 21.183 -3.282 1.00115.02 C ANISOU 191 CG HIS A 373 8246 14395 21061 -2102 2906 -151 C ATOM 192 ND1 HIS A 373 -15.880 21.706 -4.439 1.00116.46 N ANISOU 192 ND1 HIS A 373 8161 14863 21225 -1809 3066 50 N ATOM 193 CD2 HIS A 373 -16.397 20.795 -2.522 1.00115.83 C ANISOU 193 CD2 HIS A 373 8357 14541 21113 -2323 2789 -102 C ATOM 194 CE1 HIS A 373 -17.198 21.635 -4.383 1.00120.88 C ANISOU 194 CE1 HIS A 373 8534 15663 21731 -1861 2995 153 C ATOM 195 NE2 HIS A 373 -17.538 21.088 -3.230 1.00135.40 N ANISOU 195 NE2 HIS A 373 10552 17335 23558 -2203 2834 65 N ATOM 196 N THR A 374 -11.061 19.750 -2.659 1.00108.69 N ANISOU 196 N THR A 374 7828 12935 20532 -2214 2554 -1105 N ATOM 197 CA THR A 374 -9.616 19.822 -2.474 1.00114.53 C ANISOU 197 CA THR A 374 8628 13495 21395 -2143 2567 -1461 C ATOM 198 C THR A 374 -8.863 18.925 -3.444 1.00104.85 C ANISOU 198 C THR A 374 7320 12321 20198 -2119 2337 -1619 C ATOM 199 O THR A 374 -7.661 19.125 -3.648 1.00107.75 O ANISOU 199 O THR A 374 7686 12575 20679 -2004 2412 -1879 O ATOM 200 CB THR A 374 -9.239 19.441 -1.041 1.00117.42 C ANISOU 200 CB THR A 374 9091 13730 21791 -2267 2422 -1782 C ATOM 201 OG1 THR A 374 -9.773 18.146 -0.732 1.00113.66 O ANISOU 201 OG1 THR A 374 8661 13279 21246 -2479 2117 -1753 O ATOM 202 CG2 THR A 374 -9.778 20.464 -0.055 1.00115.97 C ANISOU 202 CG2 THR A 374 8938 13501 21625 -2231 2676 -1708 C ATOM 203 N GLY A 375 -9.535 17.945 -4.041 1.00 93.79 N ANISOU 203 N GLY A 375 5865 11085 18685 -2205 2034 -1512 N ATOM 204 CA GLY A 375 -8.863 17.023 -4.929 1.00 93.82 C ANISOU 204 CA GLY A 375 5986 11164 18496 -2093 1688 -1663 C ATOM 205 C GLY A 375 -8.391 15.773 -4.219 1.00139.98 C ANISOU 205 C GLY A 375 12123 16872 24193 -2248 1264 -1943 C ATOM 206 O GLY A 375 -9.157 14.822 -4.033 1.00130.15 O ANISOU 206 O GLY A 375 10996 15619 22835 -2411 998 -1888 O ATOM 207 N GLU A 376 -7.125 15.765 -3.820 1.00131.77 N ANISOU 207 N GLU A 376 11185 15704 23179 -2172 1234 -2264 N ATOM 208 CA GLU A 376 -6.488 14.591 -3.243 1.00134.58 C ANISOU 208 CA GLU A 376 11854 15957 23323 -2191 839 -2543 C ATOM 209 C GLU A 376 -6.468 14.697 -1.723 1.00131.93 C ANISOU 209 C GLU A 376 11659 15494 22972 -2219 899 -2671 C ATOM 210 O GLU A 376 -5.843 15.606 -1.167 1.00140.90 O ANISOU 210 O GLU A 376 12644 16611 24281 -2121 1116 -2912 O ATOM 211 CB GLU A 376 -5.065 14.438 -3.777 1.00137.33 C ANISOU 211 CB GLU A 376 12219 16315 23646 -2004 713 -2880 C ATOM 212 CG GLU A 376 -4.974 14.360 -5.284 1.00137.92 C ANISOU 212 CG GLU A 376 12182 16544 23679 -1874 682 -2751 C ATOM 213 CD GLU A 376 -3.558 14.551 -5.784 1.00135.07 C ANISOU 213 CD GLU A 376 11760 16169 23392 -1680 736 -3044 C ATOM 214 OE1 GLU A 376 -2.775 15.252 -5.107 1.00132.03 O ANISOU 214 OE1 GLU A 376 11248 15657 23260 -1668 972 -3330 O ATOM 215 OE2 GLU A 376 -3.226 13.997 -6.852 1.00133.47 O ANISOU 215 OE2 GLU A 376 11604 16089 23020 -1527 542 -3036 O ATOM 216 N ARG A 377 -7.149 13.766 -1.058 1.00115.86 N ANISOU 216 N ARG A 377 9901 13365 20755 -2317 738 -2533 N ATOM 217 CA ARG A 377 -6.897 13.474 0.347 1.00113.63 C ANISOU 217 CA ARG A 377 9899 12981 20293 -2189 712 -2673 C ATOM 218 C ARG A 377 -6.804 11.957 0.534 1.00110.53 C ANISOU 218 C ARG A 377 9936 12436 19626 -2150 418 -2661 C ATOM 219 O ARG A 377 -7.425 11.404 1.450 1.00114.33 O ANISOU 219 O ARG A 377 10696 12759 19985 -2148 505 -2462 O ATOM 220 CB ARG A 377 -8.000 14.087 1.214 1.00122.42 C ANISOU 220 CB ARG A 377 10946 14072 21497 -2289 1024 -2395 C ATOM 221 CG ARG A 377 -7.657 14.239 2.692 1.00129.74 C ANISOU 221 CG ARG A 377 12073 14990 22232 -2027 1079 -2582 C ATOM 222 CD ARG A 377 -8.850 14.768 3.479 1.00135.21 C ANISOU 222 CD ARG A 377 12716 15665 22994 -2120 1398 -2254 C ATOM 223 NE ARG A 377 -8.618 14.734 4.922 1.00140.19 N ANISOU 223 NE ARG A 377 13607 16318 23341 -1777 1432 -2393 N ATOM 224 CZ ARG A 377 -9.505 15.123 5.834 1.00145.86 C ANISOU 224 CZ ARG A 377 14353 17038 24029 -1746 1703 -2148 C ATOM 225 NH1 ARG A 377 -10.691 15.581 5.457 1.00148.66 N ANISOU 225 NH1 ARG A 377 14468 17359 24658 -2085 1958 -1766 N ATOM 226 NH2 ARG A 377 -9.206 15.054 7.123 1.00146.67 N ANISOU 226 NH2 ARG A 377 14722 17216 23791 -1317 1709 -2302 N ATOM 227 N PRO A 378 -6.056 11.239 -0.325 1.00110.10 N ANISOU 227 N PRO A 378 9962 12390 19483 -2099 116 -2846 N ATOM 228 CA PRO A 378 -6.112 9.776 -0.290 1.00113.59 C ANISOU 228 CA PRO A 378 10793 12630 19738 -2101 -120 -2799 C ATOM 229 C PRO A 378 -4.958 9.128 0.460 1.00121.17 C ANISOU 229 C PRO A 378 12146 13545 20348 -1736 -326 -3094 C ATOM 230 O PRO A 378 -4.036 9.803 0.928 1.00100.31 O ANISOU 230 O PRO A 378 9423 11079 17612 -1473 -347 -3432 O ATOM 231 CB PRO A 378 -6.070 9.411 -1.780 1.00116.15 C ANISOU 231 CB PRO A 378 10933 13034 20165 -2229 -349 -2841 C ATOM 232 CG PRO A 378 -5.533 10.691 -2.492 1.00114.55 C ANISOU 232 CG PRO A 378 10338 13094 20094 -2148 -229 -2956 C ATOM 233 CD PRO A 378 -5.155 11.657 -1.409 1.00111.23 C ANISOU 233 CD PRO A 378 9861 12691 19711 -2027 17 -3080 C ATOM 234 N PHE A 379 -5.020 7.807 0.588 1.00148.35 N ANISOU 234 N PHE A 379 15999 16745 23623 -1694 -462 -3005 N ATOM 235 CA PHE A 379 -3.831 7.002 0.812 1.00159.33 C ANISOU 235 CA PHE A 379 17754 18124 24662 -1327 -749 -3303 C ATOM 236 C PHE A 379 -3.327 6.520 -0.548 1.00154.31 C ANISOU 236 C PHE A 379 16996 17533 24102 -1443 -1064 -3478 C ATOM 237 O PHE A 379 -3.843 6.917 -1.597 1.00155.62 O ANISOU 237 O PHE A 379 16792 17790 24546 -1729 -1051 -3388 O ATOM 238 CB PHE A 379 -4.128 5.850 1.769 1.00174.07 C ANISOU 238 CB PHE A 379 20196 19662 26279 -1128 -643 -3069 C ATOM 239 CG PHE A 379 -4.186 6.259 3.211 1.00185.80 C ANISOU 239 CG PHE A 379 21902 21203 27490 -761 -404 -2999 C ATOM 240 CD1 PHE A 379 -3.022 6.451 3.938 1.00191.58 C ANISOU 240 CD1 PHE A 379 22788 22202 27800 -198 -599 -3410 C ATOM 241 CD2 PHE A 379 -5.403 6.449 3.843 1.00192.45 C ANISOU 241 CD2 PHE A 379 22770 21868 28486 -930 3 -2571 C ATOM 242 CE1 PHE A 379 -3.071 6.828 5.268 1.00197.23 C ANISOU 242 CE1 PHE A 379 23692 23043 28205 241 -422 -3411 C ATOM 243 CE2 PHE A 379 -5.460 6.824 5.171 1.00197.94 C ANISOU 243 CE2 PHE A 379 23684 22649 28877 -521 225 -2502 C ATOM 244 CZ PHE A 379 -4.293 7.014 5.885 1.00199.79 C ANISOU 244 CZ PHE A 379 24083 23186 28643 92 -3 -2930 C ATOM 245 N GLN A 380 -2.316 5.658 -0.556 1.00145.19 N ANISOU 245 N GLN A 380 16160 16350 22657 -1154 -1355 -3735 N ATOM 246 CA GLN A 380 -1.772 5.139 -1.800 1.00129.36 C ANISOU 246 CA GLN A 380 14073 14400 20678 -1209 -1671 -3920 C ATOM 247 C GLN A 380 -1.919 3.625 -1.853 1.00125.50 C ANISOU 247 C GLN A 380 14026 13574 20084 -1195 -1823 -3834 C ATOM 248 O GLN A 380 -2.025 2.948 -0.826 1.00121.85 O ANISOU 248 O GLN A 380 14021 12848 19429 -999 -1691 -3690 O ATOM 249 CB GLN A 380 -0.298 5.525 -1.975 1.00122.99 C ANISOU 249 CB GLN A 380 13165 13876 19691 -893 -1892 -4384 C ATOM 250 CG GLN A 380 0.631 4.942 -0.929 1.00127.44 C ANISOU 250 CG GLN A 380 14148 14439 19833 -422 -2055 -4657 C ATOM 251 CD GLN A 380 2.090 5.145 -1.281 1.00132.56 C ANISOU 251 CD GLN A 380 14639 15367 20359 -139 -2329 -5200 C ATOM 252 OE1 GLN A 380 2.435 5.363 -2.443 1.00136.33 O ANISOU 252 OE1 GLN A 380 14816 15950 21034 -300 -2413 -5299 O ATOM 253 NE2 GLN A 380 2.956 5.077 -0.277 1.00132.03 N ANISOU 253 NE2 GLN A 380 14760 15447 19956 335 -2457 -5577 N ATOM 254 N CYS A 381 -1.925 3.102 -3.076 1.00124.85 N ANISOU 254 N CYS A 381 13809 13495 20135 -1359 -2070 -3924 N ATOM 255 CA CYS A 381 -2.025 1.669 -3.304 1.00124.32 C ANISOU 255 CA CYS A 381 14089 13084 20065 -1381 -2230 -3924 C ATOM 256 C CYS A 381 -0.641 1.037 -3.288 1.00133.31 C ANISOU 256 C CYS A 381 15562 14282 20807 -971 -2549 -4233 C ATOM 257 O CYS A 381 0.333 1.629 -3.762 1.00120.99 O ANISOU 257 O CYS A 381 13783 13086 19101 -796 -2755 -4525 O ATOM 258 CB CYS A 381 -2.714 1.376 -4.637 1.00122.51 C ANISOU 258 CB CYS A 381 13512 12872 20166 -1704 -2398 -3973 C ATOM 259 SG CYS A 381 -2.749 -0.380 -5.059 1.00128.35 S ANISOU 259 SG CYS A 381 14586 13170 21010 -1752 -2627 -4113 S ATOM 260 N SER A 382 -0.563 -0.175 -2.740 1.00 96.52 N ANISOU 260 N SER A 382 8777 15851 12046 661 195 -4389 N ATOM 261 CA SER A 382 0.707 -0.876 -2.613 1.00104.30 C ANISOU 261 CA SER A 382 9615 16956 13058 713 31 -4654 C ATOM 262 C SER A 382 1.171 -1.525 -3.910 1.00102.87 C ANISOU 262 C SER A 382 9426 16759 12901 661 106 -4569 C ATOM 263 O SER A 382 2.310 -2.001 -3.968 1.00106.68 O ANISOU 263 O SER A 382 9776 17331 13426 689 3 -4796 O ATOM 264 CB SER A 382 0.608 -1.944 -1.520 1.00106.64 C ANISOU 264 CB SER A 382 9947 17389 13182 926 -234 -4728 C ATOM 265 OG SER A 382 0.242 -1.373 -0.276 1.00111.27 O ANISOU 265 OG SER A 382 10531 18013 13733 1000 -316 -4814 O ATOM 266 N LEU A 383 0.332 -1.555 -4.946 1.00101.29 N ANISOU 266 N LEU A 383 9362 16452 12672 602 274 -4261 N ATOM 267 CA LEU A 383 0.667 -2.254 -6.181 1.00 99.77 C ANISOU 267 CA LEU A 383 9175 16254 12477 582 330 -4166 C ATOM 268 C LEU A 383 0.578 -1.403 -7.440 1.00103.04 C ANISOU 268 C LEU A 383 9598 16549 13002 423 592 -4002 C ATOM 269 O LEU A 383 1.227 -1.750 -8.433 1.00113.29 O ANISOU 269 O LEU A 383 10839 17869 14336 391 652 -4002 O ATOM 270 CB LEU A 383 -0.230 -3.489 -6.356 1.00 96.40 C ANISOU 270 CB LEU A 383 8912 15837 11879 711 237 -3955 C ATOM 271 CG LEU A 383 -0.065 -4.558 -5.272 1.00 98.19 C ANISOU 271 CG LEU A 383 9132 16198 11978 892 -31 -4105 C ATOM 272 CD1 LEU A 383 -1.023 -5.714 -5.494 1.00 99.40 C ANISOU 272 CD1 LEU A 383 9441 16351 11977 1005 -101 -3889 C ATOM 273 CD2 LEU A 383 1.372 -5.053 -5.228 1.00 99.90 C ANISOU 273 CD2 LEU A 383 9186 16531 12241 939 -169 -4406 C ATOM 274 N CYS A 384 -0.193 -0.313 -7.444 1.00 94.75 N ANISOU 274 N CYS A 384 8618 15382 11999 337 748 -3865 N ATOM 275 CA CYS A 384 -0.263 0.544 -8.621 1.00 95.09 C ANISOU 275 CA CYS A 384 8672 15316 12142 198 993 -3714 C ATOM 276 C CYS A 384 -0.238 2.027 -8.271 1.00 93.35 C ANISOU 276 C CYS A 384 8385 15020 12062 73 1126 -3797 C ATOM 277 O CYS A 384 -0.427 2.859 -9.168 1.00 83.48 O ANISOU 277 O CYS A 384 7157 13670 10890 -40 1336 -3658 O ATOM 278 CB CYS A 384 -1.518 0.229 -9.449 1.00104.53 C ANISOU 278 CB CYS A 384 10076 16410 13231 236 1079 -3372 C ATOM 279 SG CYS A 384 -3.081 0.578 -8.612 1.00119.55 S ANISOU 279 SG CYS A 384 12158 18227 15039 296 1064 -3195 S ATOM 280 N SER A 385 -0.016 2.379 -7.004 1.00 98.70 N ANISOU 280 N SER A 385 8981 15747 12772 97 1005 -4027 N ATOM 281 CA SER A 385 0.064 3.764 -6.540 1.00108.26 C ANISOU 281 CA SER A 385 10107 16894 14132 -13 1104 -4165 C ATOM 282 C SER A 385 -1.214 4.551 -6.818 1.00109.61 C ANISOU 282 C SER A 385 10444 16927 14275 -42 1259 -3913 C ATOM 283 O SER A 385 -1.191 5.786 -6.850 1.00113.94 O ANISOU 283 O SER A 385 10935 17392 14965 -161 1402 -3978 O ATOM 284 CB SER A 385 1.272 4.487 -7.147 1.00116.28 C ANISOU 284 CB SER A 385 10922 17903 15355 -182 1241 -4342 C ATOM 285 OG SER A 385 2.487 3.913 -6.695 1.00119.98 O ANISOU 285 OG SER A 385 11217 18501 15868 -149 1085 -4630 O ATOM 286 N TYR A 386 -2.333 3.860 -7.019 1.00106.07 N ANISOU 286 N TYR A 386 10195 16450 13658 67 1233 -3638 N ATOM 287 CA TYR A 386 -3.611 4.539 -7.158 1.00 87.95 C ANISOU 287 CA TYR A 386 8062 14034 11322 70 1353 -3412 C ATOM 288 C TYR A 386 -4.058 5.095 -5.811 1.00 93.23 C ANISOU 288 C TYR A 386 8734 14718 11972 129 1271 -3542 C ATOM 289 O TYR A 386 -3.811 4.506 -4.755 1.00 95.66 O ANISOU 289 O TYR A 386 8998 15138 12209 230 1081 -3696 O ATOM 290 CB TYR A 386 -4.668 3.587 -7.719 1.00 75.61 C ANISOU 290 CB TYR A 386 6694 12437 9596 171 1337 -3105 C ATOM 291 CG TYR A 386 -6.091 4.044 -7.491 1.00 93.49 C ANISOU 291 CG TYR A 386 9128 14608 11784 224 1394 -2902 C ATOM 292 CD1 TYR A 386 -6.672 5.010 -8.301 1.00103.04 C ANISOU 292 CD1 TYR A 386 10410 15692 13049 157 1585 -2746 C ATOM 293 CD2 TYR A 386 -6.852 3.510 -6.461 1.00 86.10 C ANISOU 293 CD2 TYR A 386 8276 13720 10717 347 1259 -2869 C ATOM 294 CE1 TYR A 386 -7.973 5.428 -8.090 1.00 89.57 C ANISOU 294 CE1 TYR A 386 8852 13906 11273 219 1631 -2575 C ATOM 295 CE2 TYR A 386 -8.149 3.916 -6.245 1.00 71.18 C ANISOU 295 CE2 TYR A 386 6533 11754 8759 398 1317 -2689 C ATOM 296 CZ TYR A 386 -8.705 4.876 -7.059 1.00 81.02 C ANISOU 296 CZ TYR A 386 7846 12872 10067 338 1498 -2549 C ATOM 297 OH TYR A 386 -9.998 5.281 -6.836 1.00 95.59 O ANISOU 297 OH TYR A 386 9829 14645 11844 402 1548 -2385 O ATOM 298 N ALA A 387 -4.726 6.245 -5.857 1.00100.03 N ANISOU 298 N ALA A 387 9649 15470 12889 78 1414 -3483 N ATOM 299 CA ALA A 387 -5.071 6.999 -4.659 1.00103.30 C ANISOU 299 CA ALA A 387 10049 15888 13311 126 1363 -3639 C ATOM 300 C ALA A 387 -6.541 7.389 -4.711 1.00 96.49 C ANISOU 300 C ALA A 387 9385 14931 12345 194 1449 -3386 C ATOM 301 O ALA A 387 -6.953 8.145 -5.597 1.00 86.27 O ANISOU 301 O ALA A 387 8144 13518 11116 115 1630 -3253 O ATOM 302 CB ALA A 387 -4.181 8.238 -4.535 1.00112.09 C ANISOU 302 CB ALA A 387 10973 16963 14655 -19 1450 -3931 C ATOM 303 N SER A 388 -7.326 6.881 -3.761 1.00101.83 N ANISOU 303 N SER A 388 10167 15666 12859 345 1323 -3324 N ATOM 304 CA SER A 388 -8.754 7.157 -3.677 1.00 99.60 C ANISOU 304 CA SER A 388 10065 15311 12466 427 1388 -3095 C ATOM 305 C SER A 388 -9.066 7.879 -2.374 1.00 95.52 C ANISOU 305 C SER A 388 9547 14827 11919 514 1329 -3260 C ATOM 306 O SER A 388 -8.518 7.543 -1.320 1.00 92.23 O ANISOU 306 O SER A 388 9052 14529 11462 584 1169 -3459 O ATOM 307 CB SER A 388 -9.579 5.873 -3.752 1.00 95.85 C ANISOU 307 CB SER A 388 9729 14870 11818 528 1313 -2842 C ATOM 308 OG SER A 388 -9.534 5.175 -2.522 1.00 95.06 O ANISOU 308 OG SER A 388 9617 14903 11598 642 1138 -2940 O ATOM 309 N ARG A 389 -9.972 8.856 -2.453 1.00 94.42 N ANISOU 309 N ARG A 389 9502 14585 11787 529 1452 -3177 N ATOM 310 CA ARG A 389 -10.300 9.674 -1.289 1.00 85.24 C ANISOU 310 CA ARG A 389 8350 13437 10599 623 1408 -3343 C ATOM 311 C ARG A 389 -10.946 8.840 -0.188 1.00 81.77 C ANISOU 311 C ARG A 389 8006 13116 9948 789 1262 -3265 C ATOM 312 O ARG A 389 -10.427 8.754 0.931 1.00 83.40 O ANISOU 312 O ARG A 389 8144 13430 10113 867 1116 -3479 O ATOM 313 CB ARG A 389 -11.213 10.826 -1.712 1.00 75.25 C ANISOU 313 CB ARG A 389 7182 12035 9375 619 1573 -3253 C ATOM 314 CG ARG A 389 -10.560 11.800 -2.678 1.00 70.11 C ANISOU 314 CG ARG A 389 6430 11266 8945 449 1734 -3365 C ATOM 315 CD ARG A 389 -11.449 12.080 -3.879 1.00 68.78 C ANISOU 315 CD ARG A 389 6387 10980 8766 420 1907 -3088 C ATOM 316 NE ARG A 389 -10.817 13.005 -4.816 1.00 81.73 N ANISOU 316 NE ARG A 389 7933 12508 10612 245 2081 -3185 N ATOM 317 CZ ARG A 389 -11.291 13.283 -6.027 1.00 89.19 C ANISOU 317 CZ ARG A 389 8957 13355 11575 188 2244 -2974 C ATOM 318 NH1 ARG A 389 -12.402 12.702 -6.454 1.00 93.18 N ANISOU 318 NH1 ARG A 389 9627 13863 11914 303 2237 -2670 N ATOM 319 NH2 ARG A 389 -10.650 14.138 -6.813 1.00 87.02 N ANISOU 319 NH2 ARG A 389 8591 12978 11495 9 2420 -3073 N ATOM 320 N ASP A 390 -12.084 8.219 -0.487 1.00 69.50 N ANISOU 320 N ASP A 390 6602 11543 8262 845 1301 -2965 N ATOM 321 CA ASP A 390 -12.777 7.416 0.512 1.00 66.88 C ANISOU 321 CA ASP A 390 6353 11320 7737 982 1193 -2875 C ATOM 322 C ASP A 390 -11.988 6.149 0.818 1.00 59.30 C ANISOU 322 C ASP A 390 5322 10492 6717 998 1037 -2932 C ATOM 323 O ASP A 390 -11.433 5.510 -0.081 1.00 62.16 O ANISOU 323 O ASP A 390 5637 10837 7145 912 1040 -2887 O ATOM 324 CB ASP A 390 -14.183 7.061 0.028 1.00 75.05 C ANISOU 324 CB ASP A 390 7539 12293 8685 1009 1283 -2558 C ATOM 325 CG ASP A 390 -14.986 6.298 1.069 1.00 76.17 C ANISOU 325 CG ASP A 390 7754 12550 8637 1132 1199 -2465 C ATOM 326 OD1 ASP A 390 -14.676 6.418 2.273 1.00 79.21 O ANISOU 326 OD1 ASP A 390 8109 13049 8939 1227 1097 -2636 O ATOM 327 OD2 ASP A 390 -15.932 5.580 0.681 1.00 75.88 O ANISOU 327 OD2 ASP A 390 7801 12496 8536 1134 1234 -2226 O ATOM 328 N THR A 391 -11.938 5.789 2.103 1.00 64.56 N ANISOU 328 N THR A 391 5986 11297 7249 1126 898 -3038 N ATOM 329 CA THR A 391 -11.201 4.597 2.510 1.00 75.29 C ANISOU 329 CA THR A 391 7278 12795 8533 1174 734 -3111 C ATOM 330 C THR A 391 -11.850 3.324 1.982 1.00 77.16 C ANISOU 330 C THR A 391 7598 13047 8672 1177 738 -2848 C ATOM 331 O THR A 391 -11.166 2.309 1.808 1.00 49.76 O ANISOU 331 O THR A 391 4067 9652 5187 1180 633 -2885 O ATOM 332 CB THR A 391 -11.089 4.539 4.033 1.00 79.18 C ANISOU 332 CB THR A 391 7768 13434 8884 1336 586 -3268 C ATOM 333 OG1 THR A 391 -12.398 4.437 4.607 1.00 81.87 O ANISOU 333 OG1 THR A 391 8253 13799 9053 1433 634 -3068 O ATOM 334 CG2 THR A 391 -10.403 5.790 4.563 1.00 70.40 C ANISOU 334 CG2 THR A 391 6564 12299 7884 1340 559 -3562 C ATOM 335 N TYR A 392 -13.159 3.357 1.722 1.00 93.20 N ANISOU 335 N TYR A 392 9757 15010 10644 1181 849 -2599 N ATOM 336 CA TYR A 392 -13.836 2.184 1.179 1.00 95.25 C ANISOU 336 CA TYR A 392 10085 15275 10832 1174 853 -2364 C ATOM 337 C TYR A 392 -13.435 1.935 -0.270 1.00 85.86 C ANISOU 337 C TYR A 392 8870 13975 9779 1051 908 -2296 C ATOM 338 O TYR A 392 -13.248 0.783 -0.680 1.00 88.11 O ANISOU 338 O TYR A 392 9145 14303 10029 1050 839 -2234 O ATOM 339 CB TYR A 392 -15.352 2.351 1.299 1.00 94.96 C ANISOU 339 CB TYR A 392 10169 15195 10717 1204 953 -2142 C ATOM 340 CG TYR A 392 -16.148 1.228 0.671 1.00 92.71 C ANISOU 340 CG TYR A 392 9940 14902 10383 1182 963 -1908 C ATOM 341 CD1 TYR A 392 -16.682 1.358 -0.606 1.00 88.92 C ANISOU 341 CD1 TYR A 392 9505 14269 10013 1088 1069 -1750 C ATOM 342 CD2 TYR A 392 -16.364 0.038 1.353 1.00 96.53 C ANISOU 342 CD2 TYR A 392 10429 15539 10708 1264 862 -1854 C ATOM 343 CE1 TYR A 392 -17.408 0.333 -1.184 1.00 92.49 C ANISOU 343 CE1 TYR A 392 9998 14716 10428 1070 1063 -1563 C ATOM 344 CE2 TYR A 392 -17.089 -0.992 0.783 1.00 95.84 C ANISOU 344 CE2 TYR A 392 10378 15454 10581 1242 866 -1658 C ATOM 345 CZ TYR A 392 -17.609 -0.839 -0.486 1.00 93.35 C ANISOU 345 CZ TYR A 392 10099 14982 10388 1142 961 -1521 C ATOM 346 OH TYR A 392 -18.332 -1.861 -1.058 1.00 88.67 O ANISOU 346 OH TYR A 392 9532 14397 9760 1124 952 -1347 O ATOM 347 N LYS A 393 -13.302 3.002 -1.061 1.00 74.20 N ANISOU 347 N LYS A 393 7384 12360 8447 960 1035 -2310 N ATOM 348 CA LYS A 393 -12.948 2.841 -2.467 1.00 64.33 C ANISOU 348 CA LYS A 393 6122 11008 7312 854 1104 -2232 C ATOM 349 C LYS A 393 -11.525 2.328 -2.637 1.00 63.74 C ANISOU 349 C LYS A 393 5915 11008 7294 817 1007 -2420 C ATOM 350 O LYS A 393 -11.234 1.621 -3.608 1.00 63.31 O ANISOU 350 O LYS A 393 5856 10928 7272 770 1007 -2346 O ATOM 351 CB LYS A 393 -13.139 4.164 -3.203 1.00 61.15 C ANISOU 351 CB LYS A 393 5740 10460 7034 781 1270 -2205 C ATOM 352 CG LYS A 393 -14.581 4.626 -3.208 1.00 66.10 C ANISOU 352 CG LYS A 393 6496 11005 7615 826 1366 -2014 C ATOM 353 CD LYS A 393 -14.699 6.105 -3.500 1.00 72.74 C ANISOU 353 CD LYS A 393 7344 11742 8554 796 1503 -2060 C ATOM 354 CE LYS A 393 -16.112 6.584 -3.228 1.00 78.63 C ANISOU 354 CE LYS A 393 8204 12436 9236 870 1572 -1918 C ATOM 355 NZ LYS A 393 -16.243 8.056 -3.383 1.00 91.14 N ANISOU 355 NZ LYS A 393 9795 13934 10900 868 1693 -1992 N ATOM 356 N LEU A 394 -10.626 2.673 -1.713 1.00 66.68 N ANISOU 356 N LEU A 394 6178 11477 7682 844 916 -2677 N ATOM 357 CA LEU A 394 -9.300 2.068 -1.732 1.00 73.81 C ANISOU 357 CA LEU A 394 6943 12473 8630 829 795 -2876 C ATOM 358 C LEU A 394 -9.368 0.586 -1.392 1.00 80.00 C ANISOU 358 C LEU A 394 7749 13377 9269 930 643 -2825 C ATOM 359 O LEU A 394 -8.527 -0.194 -1.852 1.00 88.06 O ANISOU 359 O LEU A 394 8695 14447 10318 918 563 -2902 O ATOM 360 CB LEU A 394 -8.369 2.796 -0.762 1.00 88.42 C ANISOU 360 CB LEU A 394 8656 14399 10538 845 715 -3187 C ATOM 361 CG LEU A 394 -6.891 2.410 -0.838 1.00105.79 C ANISOU 361 CG LEU A 394 10682 16685 12830 812 601 -3439 C ATOM 362 CD1 LEU A 394 -6.361 2.619 -2.248 1.00111.17 C ANISOU 362 CD1 LEU A 394 11313 17267 13660 660 734 -3399 C ATOM 363 CD2 LEU A 394 -6.078 3.207 0.168 1.00114.40 C ANISOU 363 CD2 LEU A 394 11630 17843 13995 833 513 -3762 C ATOM 364 N LYS A 395 -10.363 0.181 -0.599 1.00 78.07 N ANISOU 364 N LYS A 395 7605 13188 8870 1035 607 -2700 N ATOM 365 CA LYS A 395 -10.527 -1.234 -0.286 1.00 70.85 C ANISOU 365 CA LYS A 395 6714 12393 7811 1137 476 -2637 C ATOM 366 C LYS A 395 -11.064 -2.003 -1.485 1.00 62.68 C ANISOU 366 C LYS A 395 5745 11282 6788 1082 533 -2424 C ATOM 367 O LYS A 395 -10.682 -3.157 -1.710 1.00 79.24 O ANISOU 367 O LYS A 395 7814 13457 8837 1128 422 -2440 O ATOM 368 CB LYS A 395 -11.446 -1.406 0.925 1.00 75.66 C ANISOU 368 CB LYS A 395 7405 13097 8244 1262 440 -2561 C ATOM 369 CG LYS A 395 -11.571 -2.844 1.404 1.00 86.87 C ANISOU 369 CG LYS A 395 8843 14667 9498 1388 304 -2511 C ATOM 370 CD LYS A 395 -12.403 -2.939 2.674 1.00 96.24 C ANISOU 370 CD LYS A 395 10108 15963 10498 1516 284 -2439 C ATOM 371 CE LYS A 395 -12.476 -4.375 3.173 1.00 93.20 C ANISOU 371 CE LYS A 395 9742 15735 9934 1656 155 -2389 C ATOM 372 NZ LYS A 395 -13.255 -4.497 4.437 1.00 87.73 N ANISOU 372 NZ LYS A 395 9135 15160 9037 1786 151 -2304 N ATOM 373 N ARG A 396 -11.949 -1.382 -2.269 1.00 45.00 N ANISOU 373 N ARG A 396 3594 8893 4612 999 693 -2237 N ATOM 374 CA ARG A 396 -12.427 -2.032 -3.481 1.00 51.85 C ANISOU 374 CA ARG A 396 4518 9679 5503 951 741 -2054 C ATOM 375 C ARG A 396 -11.423 -1.936 -4.621 1.00 42.83 C ANISOU 375 C ARG A 396 3311 8472 4490 865 772 -2129 C ATOM 376 O ARG A 396 -11.489 -2.739 -5.558 1.00 42.01 O ANISOU 376 O ARG A 396 3229 8345 4387 854 762 -2038 O ATOM 377 CB ARG A 396 -13.775 -1.447 -3.915 1.00 41.70 C ANISOU 377 CB ARG A 396 3349 8262 4234 913 885 -1834 C ATOM 378 CG ARG A 396 -13.704 -0.128 -4.657 1.00 68.95 C ANISOU 378 CG ARG A 396 6814 11559 7825 825 1038 -1825 C ATOM 379 CD ARG A 396 -15.098 0.310 -5.066 1.00 40.93 C ANISOU 379 CD ARG A 396 3380 7893 4280 816 1154 -1615 C ATOM 380 NE ARG A 396 -15.116 1.645 -5.654 1.00 41.58 N ANISOU 380 NE ARG A 396 3483 7842 4475 761 1301 -1608 N ATOM 381 CZ ARG A 396 -16.227 2.320 -5.929 1.00 40.90 C ANISOU 381 CZ ARG A 396 3484 7651 4404 766 1409 -1469 C ATOM 382 NH1 ARG A 396 -17.412 1.785 -5.664 1.00 40.12 N ANISOU 382 NH1 ARG A 396 3451 7565 4227 807 1388 -1332 N ATOM 383 NH2 ARG A 396 -16.155 3.530 -6.463 1.00 64.54 N ANISOU 383 NH2 ARG A 396 6490 10542 7491 731 1539 -1477 N ATOM 384 N HIS A 397 -10.494 -0.979 -4.562 1.00 44.04 N ANISOU 384 N HIS A 397 3376 8606 4750 808 812 -2301 N ATOM 385 CA HIS A 397 -9.387 -0.980 -5.511 1.00 44.60 C ANISOU 385 CA HIS A 397 3358 8656 4931 733 833 -2400 C ATOM 386 C HIS A 397 -8.408 -2.104 -5.204 1.00 55.10 C ANISOU 386 C HIS A 397 4589 10131 6214 797 654 -2570 C ATOM 387 O HIS A 397 -7.915 -2.773 -6.120 1.00 61.65 O ANISOU 387 O HIS A 397 5392 10962 7068 781 637 -2567 O ATOM 388 CB HIS A 397 -8.667 0.367 -5.499 1.00 67.87 C ANISOU 388 CB HIS A 397 6217 11558 8013 644 931 -2550 C ATOM 389 CG HIS A 397 -7.359 0.352 -6.227 1.00 82.49 C ANISOU 389 CG HIS A 397 7940 13430 9974 568 941 -2700 C ATOM 390 ND1 HIS A 397 -7.272 0.315 -7.602 1.00 87.52 N ANISOU 390 ND1 HIS A 397 8602 13985 10668 501 1057 -2575 N ATOM 391 CD2 HIS A 397 -6.084 0.361 -5.771 1.00 90.41 C ANISOU 391 CD2 HIS A 397 8780 14533 11038 553 851 -2971 C ATOM 392 CE1 HIS A 397 -6.001 0.307 -7.961 1.00 90.49 C ANISOU 392 CE1 HIS A 397 8837 14414 11130 445 1049 -2752 C ATOM 393 NE2 HIS A 397 -5.259 0.332 -6.869 1.00 99.34 N ANISOU 393 NE2 HIS A 397 9838 15643 12263 470 923 -2999 N ATOM 394 N MET A 398 -8.108 -2.322 -3.920 1.00 57.21 N ANISOU 394 N MET A 398 4802 10528 6407 889 513 -2729 N ATOM 395 CA MET A 398 -7.276 -3.455 -3.529 1.00 81.29 C ANISOU 395 CA MET A 398 7769 13724 9392 987 319 -2892 C ATOM 396 C MET A 398 -7.917 -4.784 -3.896 1.00 78.12 C ANISOU 396 C MET A 398 7451 13356 8876 1066 251 -2733 C ATOM 397 O MET A 398 -7.215 -5.797 -3.990 1.00 74.38 O ANISOU 397 O MET A 398 6919 12976 8367 1141 107 -2846 O ATOM 398 CB MET A 398 -6.992 -3.414 -2.026 1.00101.53 C ANISOU 398 CB MET A 398 10278 16421 11877 1102 174 -3072 C ATOM 399 CG MET A 398 -6.120 -2.249 -1.581 1.00120.68 C ANISOU 399 CG MET A 398 12582 18846 14425 1042 190 -3307 C ATOM 400 SD MET A 398 -4.495 -2.243 -2.362 1.00139.67 S ANISOU 400 SD MET A 398 14807 21267 16992 953 161 -3551 S ATOM 401 CE MET A 398 -3.865 -3.841 -1.853 1.00135.55 C ANISOU 401 CE MET A 398 14239 20918 16345 1132 -105 -3687 C ATOM 402 N ARG A 399 -9.235 -4.801 -4.104 1.00 74.41 N ANISOU 402 N ARG A 399 7108 12813 8350 1056 344 -2489 N ATOM 403 CA ARG A 399 -9.908 -6.011 -4.553 1.00 68.55 C ANISOU 403 CA ARG A 399 6432 12098 7515 1116 292 -2341 C ATOM 404 C ARG A 399 -9.595 -6.333 -6.008 1.00 58.61 C ANISOU 404 C ARG A 399 5170 10761 6339 1051 337 -2300 C ATOM 405 O ARG A 399 -9.843 -7.460 -6.449 1.00 58.28 O ANISOU 405 O ARG A 399 5152 10763 6229 1116 257 -2244 O ATOM 406 CB ARG A 399 -11.419 -5.866 -4.356 1.00 76.57 C ANISOU 406 CB ARG A 399 7566 13065 8462 1113 384 -2105 C ATOM 407 CG ARG A 399 -12.162 -7.187 -4.303 1.00 90.41 C ANISOU 407 CG ARG A 399 9362 14910 10080 1208 297 -1986 C ATOM 408 CD ARG A 399 -13.663 -7.000 -4.124 1.00 92.07 C ANISOU 408 CD ARG A 399 9669 15082 10233 1190 398 -1757 C ATOM 409 NE ARG A 399 -13.999 -6.316 -2.879 1.00 86.42 N ANISOU 409 NE ARG A 399 8970 14413 9454 1223 425 -1767 N ATOM 410 CZ ARG A 399 -14.577 -5.121 -2.814 1.00 80.38 C ANISOU 410 CZ ARG A 399 8253 13534 8754 1150 560 -1700 C ATOM 411 NH1 ARG A 399 -14.897 -4.477 -3.928 1.00 78.50 N ANISOU 411 NH1 ARG A 399 8055 13125 8645 1044 682 -1609 N ATOM 412 NH2 ARG A 399 -14.845 -4.576 -1.637 1.00 80.89 N ANISOU 412 NH2 ARG A 399 8330 13659 8744 1202 569 -1729 N ATOM 413 N THR A 400 -9.059 -5.370 -6.762 1.00 53.85 N ANISOU 413 N THR A 400 4536 10053 5873 936 465 -2329 N ATOM 414 CA THR A 400 -8.749 -5.619 -8.166 1.00 52.03 C ANISOU 414 CA THR A 400 4305 9758 5706 886 524 -2284 C ATOM 415 C THR A 400 -7.604 -6.614 -8.311 1.00 75.48 C ANISOU 415 C THR A 400 7173 12847 8658 953 373 -2472 C ATOM 416 O THR A 400 -7.641 -7.491 -9.183 1.00 79.90 O ANISOU 416 O THR A 400 7753 13416 9189 990 335 -2428 O ATOM 417 CB THR A 400 -8.413 -4.301 -8.867 1.00 43.12 C ANISOU 417 CB THR A 400 3161 8508 4713 762 708 -2269 C ATOM 418 OG1 THR A 400 -9.488 -3.373 -8.679 1.00 51.94 O ANISOU 418 OG1 THR A 400 4376 9516 5843 724 832 -2111 O ATOM 419 CG2 THR A 400 -8.200 -4.521 -10.352 1.00 46.36 C ANISOU 419 CG2 THR A 400 3585 8860 5172 724 789 -2195 C ATOM 420 N HIS A 401 -6.591 -6.506 -7.452 1.00 82.25 N ANISOU 420 N HIS A 401 7919 13803 9530 984 273 -2700 N ATOM 421 CA HIS A 401 -5.408 -7.353 -7.501 1.00 74.07 C ANISOU 421 CA HIS A 401 6775 12882 8487 1057 118 -2914 C ATOM 422 C HIS A 401 -5.591 -8.670 -6.757 1.00 77.84 C ANISOU 422 C HIS A 401 7274 13484 8819 1231 -98 -2964 C ATOM 423 O HIS A 401 -4.608 -9.384 -6.534 1.00 86.76 O ANISOU 423 O HIS A 401 8319 14717 9927 1328 -265 -3172 O ATOM 424 CB HIS A 401 -4.205 -6.600 -6.928 1.00 76.12 C ANISOU 424 CB HIS A 401 6893 13192 8839 1015 100 -3160 C ATOM 425 CG HIS A 401 -4.283 -5.116 -7.104 1.00 87.12 C ANISOU 425 CG HIS A 401 8275 14474 10351 867 299 -3114 C ATOM 426 ND1 HIS A 401 -4.515 -4.523 -8.327 1.00 91.78 N ANISOU 426 ND1 HIS A 401 8908 14942 11022 756 494 -2958 N ATOM 427 CD2 HIS A 401 -4.159 -4.105 -6.213 1.00 89.99 C ANISOU 427 CD2 HIS A 401 8591 14836 10765 828 326 -3215 C ATOM 428 CE1 HIS A 401 -4.532 -3.211 -8.180 1.00 94.49 C ANISOU 428 CE1 HIS A 401 9232 15209 11460 655 634 -2960 C ATOM 429 NE2 HIS A 401 -4.319 -2.931 -6.907 1.00 98.64 N ANISOU 429 NE2 HIS A 401 9700 15806 11974 692 535 -3122 N ATOM 430 N SER A 402 -6.817 -9.004 -6.366 1.00 80.51 N ANISOU 430 N SER A 402 7720 13815 9054 1283 -100 -2783 N ATOM 431 CA SER A 402 -7.097 -10.249 -5.670 1.00 89.70 C ANISOU 431 CA SER A 402 8912 15101 10069 1462 -288 -2805 C ATOM 432 C SER A 402 -8.341 -10.890 -6.267 1.00 94.27 C ANISOU 432 C SER A 402 9599 15641 10579 1478 -243 -2574 C ATOM 433 O SER A 402 -9.229 -10.202 -6.776 1.00 97.06 O ANISOU 433 O SER A 402 10017 15882 10978 1359 -71 -2381 O ATOM 434 CB SER A 402 -7.290 -10.022 -4.163 1.00 89.59 C ANISOU 434 CB SER A 402 8896 15175 9967 1548 -358 -2853 C ATOM 435 OG SER A 402 -7.522 -11.248 -3.493 1.00 91.16 O ANISOU 435 OG SER A 402 9129 15498 10011 1748 -540 -2869 O ATOM 436 N GLY A 403 -8.395 -12.218 -6.201 1.00 92.35 N ANISOU 436 N GLY A 403 9373 15489 10227 1640 -411 -2609 N ATOM 437 CA GLY A 403 -9.537 -12.947 -6.715 1.00 88.65 C ANISOU 437 CA GLY A 403 8987 15008 9687 1677 -393 -2419 C ATOM 438 C GLY A 403 -10.694 -12.970 -5.739 1.00 89.79 C ANISOU 438 C GLY A 403 9189 15211 9715 1722 -361 -2257 C ATOM 439 O GLY A 403 -11.396 -13.977 -5.612 1.00 96.35 O ANISOU 439 O GLY A 403 10061 16117 10429 1846 -434 -2171 O ATOM 440 N GLU A 404 -10.901 -11.854 -5.045 1.00 89.12 N ANISOU 440 N GLU A 404 9106 15097 9657 1630 -247 -2215 N ATOM 441 CA GLU A 404 -11.954 -11.731 -4.044 1.00 84.97 C ANISOU 441 CA GLU A 404 8635 14636 9015 1664 -196 -2064 C ATOM 442 C GLU A 404 -13.200 -11.170 -4.718 1.00 64.04 C ANISOU 442 C GLU A 404 6051 11869 6414 1520 -12 -1822 C ATOM 443 O GLU A 404 -13.219 -10.009 -5.138 1.00 56.04 O ANISOU 443 O GLU A 404 5053 10713 5528 1377 124 -1793 O ATOM 444 CB GLU A 404 -11.497 -10.838 -2.895 1.00 93.20 C ANISOU 444 CB GLU A 404 9650 15708 10053 1666 -191 -2173 C ATOM 445 CG GLU A 404 -12.529 -10.660 -1.795 1.00 94.49 C ANISOU 445 CG GLU A 404 9878 15946 10078 1710 -131 -2025 C ATOM 446 CD GLU A 404 -12.035 -9.764 -0.679 1.00 92.32 C ANISOU 446 CD GLU A 404 9580 15700 9795 1730 -139 -2155 C ATOM 447 OE1 GLU A 404 -10.922 -9.211 -0.809 1.00 88.27 O ANISOU 447 OE1 GLU A 404 8987 15147 9403 1691 -182 -2357 O ATOM 448 OE2 GLU A 404 -12.758 -9.614 0.329 1.00 91.65 O ANISOU 448 OE2 GLU A 404 9555 15688 9579 1786 -101 -2058 O ATOM 449 N LYS A 405 -14.235 -11.999 -4.838 1.00 55.01 N ANISOU 449 N LYS A 405 4943 10786 5171 1571 -14 -1654 N ATOM 450 CA LYS A 405 -15.518 -11.594 -5.409 1.00 52.77 C ANISOU 450 CA LYS A 405 4714 10411 4925 1455 135 -1424 C ATOM 451 C LYS A 405 -16.606 -11.975 -4.416 1.00 54.51 C ANISOU 451 C LYS A 405 4960 10764 4988 1511 161 -1255 C ATOM 452 O LYS A 405 -17.271 -13.011 -4.565 1.00 55.55 O ANISOU 452 O LYS A 405 5086 11002 5019 1576 128 -1134 O ATOM 453 CB LYS A 405 -15.747 -12.240 -6.776 1.00 45.83 C ANISOU 453 CB LYS A 405 3836 9480 4096 1440 119 -1374 C ATOM 454 CG LYS A 405 -14.666 -11.938 -7.809 1.00 51.06 C ANISOU 454 CG LYS A 405 4480 10031 4889 1390 107 -1523 C ATOM 455 CD LYS A 405 -14.892 -12.724 -9.095 1.00 55.93 C ANISOU 455 CD LYS A 405 5103 10627 5523 1413 70 -1488 C ATOM 456 CE LYS A 405 -13.732 -12.557 -10.068 1.00 50.53 C ANISOU 456 CE LYS A 405 4394 9868 4937 1385 54 -1640 C ATOM 457 NZ LYS A 405 -13.902 -13.393 -11.292 1.00 38.24 N ANISOU 457 NZ LYS A 405 2846 8308 3374 1437 0 -1629 N ATOM 458 N PRO A 406 -16.820 -11.155 -3.383 1.00 48.14 N ANISOU 458 N PRO A 406 4179 9964 4146 1489 229 -1234 N ATOM 459 CA PRO A 406 -17.768 -11.530 -2.322 1.00 54.41 C ANISOU 459 CA PRO A 406 5008 10903 4763 1545 261 -1070 C ATOM 460 C PRO A 406 -19.228 -11.447 -2.734 1.00 58.08 C ANISOU 460 C PRO A 406 5497 11323 5247 1443 385 -817 C ATOM 461 O PRO A 406 -20.093 -11.859 -1.949 1.00 66.31 O ANISOU 461 O PRO A 406 6563 12491 6141 1465 424 -644 O ATOM 462 CB PRO A 406 -17.453 -10.527 -1.206 1.00 58.78 C ANISOU 462 CB PRO A 406 5581 11452 5301 1553 293 -1159 C ATOM 463 CG PRO A 406 -16.935 -9.327 -1.930 1.00 52.95 C ANISOU 463 CG PRO A 406 4830 10517 4771 1433 352 -1270 C ATOM 464 CD PRO A 406 -16.179 -9.853 -3.122 1.00 48.31 C ANISOU 464 CD PRO A 406 4202 9874 4281 1418 282 -1362 C ATOM 465 N TYR A 407 -19.534 -10.936 -3.922 1.00 50.86 N ANISOU 465 N TYR A 407 4589 10235 4500 1331 446 -783 N ATOM 466 CA TYR A 407 -20.908 -10.777 -4.379 1.00 45.70 C ANISOU 466 CA TYR A 407 3956 9521 3886 1243 544 -572 C ATOM 467 C TYR A 407 -21.232 -11.886 -5.373 1.00 48.74 C ANISOU 467 C TYR A 407 4299 9957 4262 1256 489 -490 C ATOM 468 O TYR A 407 -20.643 -11.944 -6.458 1.00 48.32 O ANISOU 468 O TYR A 407 4241 9813 4306 1250 446 -593 O ATOM 469 CB TYR A 407 -21.109 -9.401 -5.012 1.00 41.82 C ANISOU 469 CB TYR A 407 3517 8804 3570 1136 647 -594 C ATOM 470 CG TYR A 407 -20.570 -8.267 -4.168 1.00 50.14 C ANISOU 470 CG TYR A 407 4598 9805 4649 1134 690 -714 C ATOM 471 CD1 TYR A 407 -21.326 -7.721 -3.139 1.00 57.38 C ANISOU 471 CD1 TYR A 407 5540 10757 5506 1142 759 -641 C ATOM 472 CD2 TYR A 407 -19.303 -7.746 -4.397 1.00 53.09 C ANISOU 472 CD2 TYR A 407 4961 10107 5105 1128 664 -904 C ATOM 473 CE1 TYR A 407 -20.837 -6.686 -2.363 1.00 59.11 C ANISOU 473 CE1 TYR A 407 5778 10943 5739 1156 792 -763 C ATOM 474 CE2 TYR A 407 -18.806 -6.711 -3.627 1.00 57.65 C ANISOU 474 CE2 TYR A 407 5546 10652 5705 1128 700 -1018 C ATOM 475 CZ TYR A 407 -19.577 -6.185 -2.612 1.00 59.73 C ANISOU 475 CZ TYR A 407 5840 10954 5902 1148 760 -952 C ATOM 476 OH TYR A 407 -19.086 -5.154 -1.843 1.00 64.96 O ANISOU 476 OH TYR A 407 6506 11597 6579 1164 788 -1079 O ATOM 477 N GLU A 408 -22.163 -12.759 -5.003 1.00 51.04 N ANISOU 477 N GLU A 408 4557 10403 4432 1272 497 -295 N ATOM 478 CA GLU A 408 -22.525 -13.915 -5.811 1.00 61.71 C ANISOU 478 CA GLU A 408 5844 11842 5761 1296 440 -198 C ATOM 479 C GLU A 408 -23.943 -13.768 -6.340 1.00 66.02 C ANISOU 479 C GLU A 408 6368 12339 6378 1184 525 19 C ATOM 480 O GLU A 408 -24.856 -13.395 -5.595 1.00 68.14 O ANISOU 480 O GLU A 408 6655 12621 6616 1118 612 171 O ATOM 481 CB GLU A 408 -22.406 -15.211 -5.005 1.00 75.83 C ANISOU 481 CB GLU A 408 7760 13581 7473 1301 220 -87 C ATOM 482 CG GLU A 408 -20.983 -15.590 -4.637 1.00 93.32 C ANISOU 482 CG GLU A 408 10031 15776 9652 1417 52 -305 C ATOM 483 CD GLU A 408 -20.891 -16.978 -4.033 1.00100.51 C ANISOU 483 CD GLU A 408 11091 16596 10500 1430 -199 -184 C ATOM 484 OE1 GLU A 408 -21.930 -17.669 -3.968 1.00 99.02 O ANISOU 484 OE1 GLU A 408 10960 16350 10312 1328 -238 77 O ATOM 485 OE2 GLU A 408 -19.780 -17.377 -3.626 1.00102.26 O ANISOU 485 OE2 GLU A 408 11373 16801 10679 1540 -364 -351 O ATOM 486 N CYS A 409 -24.120 -14.062 -7.624 1.00 61.21 N ANISOU 486 N CYS A 409 5719 11667 5869 1173 486 19 N ATOM 487 CA CYS A 409 -25.453 -14.171 -8.201 1.00 73.31 C ANISOU 487 CA CYS A 409 7206 13184 7464 1088 530 219 C ATOM 488 C CYS A 409 -26.124 -15.438 -7.683 1.00 82.22 C ANISOU 488 C CYS A 409 8398 14261 8582 1005 369 444 C ATOM 489 O CYS A 409 -25.624 -16.544 -7.903 1.00 89.36 O ANISOU 489 O CYS A 409 9392 15046 9517 1017 141 430 O ATOM 490 CB CYS A 409 -25.361 -14.185 -9.725 1.00 74.58 C ANISOU 490 CB CYS A 409 7362 13232 7742 1100 477 140 C ATOM 491 SG CYS A 409 -26.778 -14.922 -10.568 1.00 72.96 S ANISOU 491 SG CYS A 409 7118 12970 7633 1016 395 363 S ATOM 492 N TYR A 410 -27.253 -15.283 -6.987 1.00 72.26 N ANISOU 492 N TYR A 410 7093 13084 7280 920 484 650 N ATOM 493 CA TYR A 410 -27.932 -16.438 -6.406 1.00 67.18 C ANISOU 493 CA TYR A 410 6506 12394 6626 814 357 890 C ATOM 494 C TYR A 410 -28.612 -17.318 -7.446 1.00 61.07 C ANISOU 494 C TYR A 410 5724 11477 6004 728 198 1006 C ATOM 495 O TYR A 410 -29.262 -18.298 -7.066 1.00 58.85 O ANISOU 495 O TYR A 410 5481 11133 5745 614 86 1220 O ATOM 496 CB TYR A 410 -28.964 -15.984 -5.370 1.00 74.18 C ANISOU 496 CB TYR A 410 7327 13438 7421 744 551 1079 C ATOM 497 CG TYR A 410 -30.094 -15.153 -5.938 1.00 80.32 C ANISOU 497 CG TYR A 410 7952 14295 8273 704 733 1141 C ATOM 498 CD1 TYR A 410 -31.304 -15.736 -6.300 1.00 82.48 C ANISOU 498 CD1 TYR A 410 8153 14537 8648 576 698 1356 C ATOM 499 CD2 TYR A 410 -29.952 -13.783 -6.108 1.00 82.40 C ANISOU 499 CD2 TYR A 410 8267 14448 8594 767 815 945 C ATOM 500 CE1 TYR A 410 -32.338 -14.974 -6.818 1.00 82.40 C ANISOU 500 CE1 TYR A 410 8038 14544 8728 552 815 1382 C ATOM 501 CE2 TYR A 410 -30.977 -13.016 -6.624 1.00 86.47 C ANISOU 501 CE2 TYR A 410 8780 14842 9233 726 866 959 C ATOM 502 CZ TYR A 410 -32.167 -13.614 -6.978 1.00 85.48 C ANISOU 502 CZ TYR A 410 8542 14773 9162 635 866 1162 C ATOM 503 OH TYR A 410 -33.184 -12.842 -7.491 1.00 87.67 O ANISOU 503 OH TYR A 410 8813 14948 9548 616 912 1155 O ATOM 504 N ILE A 411 -28.483 -17.001 -8.732 1.00 61.11 N ANISOU 504 N ILE A 411 5686 11424 6109 777 183 873 N ATOM 505 CA ILE A 411 -29.117 -17.762 -9.804 1.00 57.87 C ANISOU 505 CA ILE A 411 5269 10881 5840 718 21 951 C ATOM 506 C ILE A 411 -28.095 -18.603 -10.562 1.00 57.26 C ANISOU 506 C ILE A 411 5300 10649 5806 801 -222 794 C ATOM 507 O ILE A 411 -28.204 -19.830 -10.612 1.00 54.12 O ANISOU 507 O ILE A 411 4987 10108 5468 750 -458 885 O ATOM 508 CB ILE A 411 -29.891 -16.827 -10.762 1.00 61.78 C ANISOU 508 CB ILE A 411 5641 11428 6404 726 170 934 C ATOM 509 CG1 ILE A 411 -30.935 -16.025 -9.983 1.00 70.81 C ANISOU 509 CG1 ILE A 411 6668 12731 7507 662 399 1081 C ATOM 510 CG2 ILE A 411 -30.538 -17.629 -11.878 1.00 68.32 C ANISOU 510 CG2 ILE A 411 6464 12119 7374 679 -20 999 C ATOM 511 CD1 ILE A 411 -31.682 -15.020 -10.823 1.00 69.03 C ANISOU 511 CD1 ILE A 411 6328 12561 7338 691 545 1055 C ATOM 512 N CYS A 412 -27.095 -17.960 -11.160 1.00 64.04 N ANISOU 512 N CYS A 412 6157 11536 6640 930 -169 555 N ATOM 513 CA CYS A 412 -26.063 -18.651 -11.918 1.00 67.16 C ANISOU 513 CA CYS A 412 6633 11820 7064 1032 -372 375 C ATOM 514 C CYS A 412 -24.780 -18.844 -11.120 1.00 65.71 C ANISOU 514 C CYS A 412 6519 11656 6793 1118 -431 230 C ATOM 515 O CYS A 412 -23.780 -19.303 -11.681 1.00 81.79 O ANISOU 515 O CYS A 412 8603 13631 8842 1226 -579 44 O ATOM 516 CB CYS A 412 -25.767 -17.898 -13.217 1.00 71.15 C ANISOU 516 CB CYS A 412 7084 12351 7599 1119 -279 205 C ATOM 517 SG CYS A 412 -25.051 -16.253 -12.997 1.00 67.47 S ANISOU 517 SG CYS A 412 6535 12048 7052 1182 28 37 S ATOM 518 N HIS A 413 -24.789 -18.505 -9.829 1.00 65.63 N ANISOU 518 N HIS A 413 6510 11739 6687 1085 -325 299 N ATOM 519 CA HIS A 413 -23.632 -18.675 -8.947 1.00 81.49 C ANISOU 519 CA HIS A 413 8587 13772 8603 1172 -394 167 C ATOM 520 C HIS A 413 -22.401 -17.937 -9.468 1.00 82.96 C ANISOU 520 C HIS A 413 8716 14020 8786 1298 -323 -126 C ATOM 521 O HIS A 413 -21.266 -18.374 -9.259 1.00 84.74 O ANISOU 521 O HIS A 413 8988 14224 8984 1399 -464 -295 O ATOM 522 CB HIS A 413 -23.318 -20.157 -8.721 1.00 94.01 C ANISOU 522 CB HIS A 413 10317 15204 10199 1187 -701 217 C ATOM 523 CG HIS A 413 -24.325 -20.861 -7.864 1.00101.53 C ANISOU 523 CG HIS A 413 11340 16106 11130 1052 -757 511 C ATOM 524 ND1 HIS A 413 -25.245 -20.186 -7.091 1.00103.51 N ANISOU 524 ND1 HIS A 413 11524 16486 11319 951 -535 689 N ATOM 525 CD2 HIS A 413 -24.556 -22.179 -7.659 1.00106.11 C ANISOU 525 CD2 HIS A 413 12051 16521 11743 998 -1006 663 C ATOM 526 CE1 HIS A 413 -25.999 -21.058 -6.445 1.00106.30 C ANISOU 526 CE1 HIS A 413 11953 16773 11663 832 -627 945 C ATOM 527 NE2 HIS A 413 -25.601 -22.275 -6.772 1.00108.60 N ANISOU 527 NE2 HIS A 413 12372 16874 12018 849 -916 941 N ATOM 528 N ALA A 414 -22.616 -16.811 -10.145 1.00 71.71 N ANISOU 528 N ALA A 414 7186 12670 7391 1290 -105 -185 N ATOM 529 CA ALA A 414 -21.512 -15.983 -10.604 1.00 58.38 C ANISOU 529 CA ALA A 414 5431 11047 5705 1379 3 -438 C ATOM 530 C ALA A 414 -20.858 -15.282 -9.414 1.00 57.95 C ANISOU 530 C ALA A 414 5351 11098 5568 1406 106 -537 C ATOM 531 O ALA A 414 -21.276 -15.425 -8.263 1.00 59.33 O ANISOU 531 O ALA A 414 5571 11305 5666 1371 100 -409 O ATOM 532 CB ALA A 414 -22.000 -14.971 -11.637 1.00 40.88 C ANISOU 532 CB ALA A 414 3139 8854 3539 1350 202 -441 C ATOM 533 N ARG A 415 -19.811 -14.512 -9.699 1.00 54.90 N ANISOU 533 N ARG A 415 4963 10681 5217 1423 167 -746 N ATOM 534 CA ARG A 415 -19.083 -13.786 -8.667 1.00 57.85 C ANISOU 534 CA ARG A 415 5370 11044 5568 1405 200 -848 C ATOM 535 C ARG A 415 -18.612 -12.453 -9.226 1.00 49.36 C ANISOU 535 C ARG A 415 4357 9766 4632 1283 300 -919 C ATOM 536 O ARG A 415 -18.069 -12.397 -10.333 1.00 36.33 O ANISOU 536 O ARG A 415 2716 8028 3061 1268 289 -1000 O ATOM 537 CB ARG A 415 -17.894 -14.603 -8.145 1.00 64.71 C ANISOU 537 CB ARG A 415 6193 12024 6371 1560 41 -1044 C ATOM 538 CG ARG A 415 -18.269 -15.670 -7.125 1.00 71.40 C ANISOU 538 CG ARG A 415 7116 12898 7116 1606 -123 -909 C ATOM 539 CD ARG A 415 -17.037 -16.338 -6.530 1.00 78.46 C ANISOU 539 CD ARG A 415 8055 13786 7970 1728 -336 -1091 C ATOM 540 NE ARG A 415 -17.389 -17.339 -5.526 1.00 91.66 N ANISOU 540 NE ARG A 415 9881 15402 9545 1735 -523 -921 N ATOM 541 CZ ARG A 415 -16.506 -18.087 -4.872 1.00111.87 C ANISOU 541 CZ ARG A 415 12524 17934 12047 1847 -747 -1027 C ATOM 542 NH1 ARG A 415 -15.209 -17.953 -5.114 1.00118.78 N ANISOU 542 NH1 ARG A 415 13319 18847 12964 1965 -815 -1320 N ATOM 543 NH2 ARG A 415 -16.920 -18.973 -3.975 1.00117.85 N ANISOU 543 NH2 ARG A 415 13443 18629 12706 1842 -905 -836 N ATOM 544 N PHE A 416 -18.823 -11.385 -8.458 1.00 48.79 N ANISOU 544 N PHE A 416 4320 9629 4588 1209 400 -884 N ATOM 545 CA PHE A 416 -18.518 -10.032 -8.893 1.00 43.06 C ANISOU 545 CA PHE A 416 3645 8715 4000 1105 510 -924 C ATOM 546 C PHE A 416 -17.770 -9.288 -7.798 1.00 42.85 C ANISOU 546 C PHE A 416 3611 8695 3977 1103 525 -1040 C ATOM 547 O PHE A 416 -17.908 -9.591 -6.609 1.00 37.43 O ANISOU 547 O PHE A 416 2904 8138 3179 1166 482 -1037 O ATOM 548 CB PHE A 416 -19.794 -9.261 -9.263 1.00 37.55 C ANISOU 548 CB PHE A 416 3006 7900 3363 1026 632 -756 C ATOM 549 CG PHE A 416 -20.560 -9.873 -10.397 1.00 35.37 C ANISOU 549 CG PHE A 416 2731 7618 3092 1028 617 -652 C ATOM 550 CD1 PHE A 416 -20.352 -9.449 -11.699 1.00 34.52 C ANISOU 550 CD1 PHE A 416 2658 7381 3076 991 661 -676 C ATOM 551 CD2 PHE A 416 -21.482 -10.880 -10.164 1.00 44.97 C ANISOU 551 CD2 PHE A 416 3901 8974 4211 1072 564 -525 C ATOM 552 CE1 PHE A 416 -21.051 -10.015 -12.746 1.00 46.17 C ANISOU 552 CE1 PHE A 416 4131 8870 4543 1011 636 -595 C ATOM 553 CE2 PHE A 416 -22.184 -11.450 -11.205 1.00 51.67 C ANISOU 553 CE2 PHE A 416 4732 9833 5066 1082 541 -438 C ATOM 554 CZ PHE A 416 -21.968 -11.018 -12.498 1.00 57.51 C ANISOU 554 CZ PHE A 416 5514 10445 5892 1059 569 -484 C ATOM 555 N THR A 417 -16.976 -8.303 -8.214 1.00 43.79 N ANISOU 555 N THR A 417 3739 8684 4214 1037 590 -1138 N ATOM 556 CA THR A 417 -16.214 -7.493 -7.275 1.00 47.76 C ANISOU 556 CA THR A 417 4219 9190 4736 1031 605 -1264 C ATOM 557 C THR A 417 -17.023 -6.347 -6.681 1.00 42.19 C ANISOU 557 C THR A 417 3568 8405 4056 985 723 -1179 C ATOM 558 O THR A 417 -16.588 -5.760 -5.685 1.00 52.67 O ANISOU 558 O THR A 417 4875 9770 5366 1004 723 -1277 O ATOM 559 CB THR A 417 -14.963 -6.935 -7.957 1.00 60.30 C ANISOU 559 CB THR A 417 5772 10698 6440 980 630 -1408 C ATOM 560 OG1 THR A 417 -15.327 -6.324 -9.202 1.00 72.82 O ANISOU 560 OG1 THR A 417 7413 12126 8129 901 752 -1309 O ATOM 561 CG2 THR A 417 -13.956 -8.049 -8.216 1.00 58.59 C ANISOU 561 CG2 THR A 417 5484 10591 6185 1050 487 -1548 C ATOM 562 N GLN A 418 -18.177 -6.015 -7.258 1.00 44.26 N ANISOU 562 N GLN A 418 3893 8568 4357 940 813 -1019 N ATOM 563 CA GLN A 418 -19.028 -4.947 -6.755 1.00 45.39 C ANISOU 563 CA GLN A 418 4086 8635 4525 912 920 -947 C ATOM 564 C GLN A 418 -20.475 -5.418 -6.720 1.00 45.12 C ANISOU 564 C GLN A 418 4078 8635 4432 922 930 -771 C ATOM 565 O GLN A 418 -20.909 -6.202 -7.568 1.00 46.21 O ANISOU 565 O GLN A 418 4212 8782 4565 917 896 -688 O ATOM 566 CB GLN A 418 -18.914 -3.677 -7.613 1.00 36.54 C ANISOU 566 CB GLN A 418 3011 7328 3547 843 1048 -953 C ATOM 567 CG GLN A 418 -17.511 -3.099 -7.692 1.00 37.16 C ANISOU 567 CG GLN A 418 3047 7377 3695 820 1061 -1113 C ATOM 568 CD GLN A 418 -17.477 -1.751 -8.378 1.00 39.42 C ANISOU 568 CD GLN A 418 3374 7503 4103 763 1209 -1100 C ATOM 569 OE1 GLN A 418 -18.508 -1.096 -8.539 1.00 37.00 O ANISOU 569 OE1 GLN A 418 3131 7107 3821 754 1297 -994 O ATOM 570 NE2 GLN A 418 -16.289 -1.327 -8.790 1.00 56.93 N ANISOU 570 NE2 GLN A 418 5544 9694 6392 728 1238 -1211 N ATOM 571 N SER A 419 -21.219 -4.931 -5.721 1.00 36.94 N ANISOU 571 N SER A 419 3059 7631 3346 939 975 -722 N ATOM 572 CA SER A 419 -22.632 -5.286 -5.612 1.00 46.38 C ANISOU 572 CA SER A 419 4262 8868 4491 941 997 -555 C ATOM 573 C SER A 419 -23.444 -4.686 -6.754 1.00 57.42 C ANISOU 573 C SER A 419 5703 10111 6003 886 1074 -477 C ATOM 574 O SER A 419 -24.310 -5.359 -7.327 1.00 62.75 O ANISOU 574 O SER A 419 6364 10815 6664 879 1053 -359 O ATOM 575 CB SER A 419 -23.193 -4.827 -4.266 1.00 49.85 C ANISOU 575 CB SER A 419 4707 9384 4848 979 1037 -532 C ATOM 576 OG SER A 419 -23.327 -3.417 -4.218 1.00 54.09 O ANISOU 576 OG SER A 419 5288 9792 5473 959 1134 -585 O ATOM 577 N GLY A 420 -23.184 -3.420 -7.091 1.00 53.79 N ANISOU 577 N GLY A 420 5288 9501 5647 856 1164 -543 N ATOM 578 CA GLY A 420 -23.889 -2.796 -8.200 1.00 56.40 C ANISOU 578 CA GLY A 420 5662 9694 6073 820 1240 -481 C ATOM 579 C GLY A 420 -23.635 -3.494 -9.522 1.00 53.44 C ANISOU 579 C GLY A 420 5285 9289 5730 800 1198 -458 C ATOM 580 O GLY A 420 -24.550 -3.662 -10.332 1.00 52.80 O ANISOU 580 O GLY A 420 5212 9185 5664 794 1203 -366 O ATOM 581 N THR A 421 -22.387 -3.907 -9.759 1.00 51.04 N ANISOU 581 N THR A 421 4961 9002 5431 799 1151 -552 N ATOM 582 CA THR A 421 -22.083 -4.693 -10.950 1.00 51.22 C ANISOU 582 CA THR A 421 4973 9026 5461 797 1100 -544 C ATOM 583 C THR A 421 -22.793 -6.040 -10.909 1.00 51.20 C ANISOU 583 C THR A 421 4924 9168 5362 837 995 -455 C ATOM 584 O THR A 421 -23.297 -6.520 -11.932 1.00 44.26 O ANISOU 584 O THR A 421 4042 8288 4485 843 972 -391 O ATOM 585 CB THR A 421 -20.571 -4.882 -11.078 1.00 39.55 C ANISOU 585 CB THR A 421 3467 7562 3999 798 1067 -678 C ATOM 586 OG1 THR A 421 -19.933 -3.599 -11.125 1.00 41.83 O ANISOU 586 OG1 THR A 421 3783 7730 4380 758 1178 -745 O ATOM 587 CG2 THR A 421 -20.230 -5.655 -12.343 1.00 34.21 C ANISOU 587 CG2 THR A 421 2780 6895 3325 808 1020 -683 C ATOM 588 N MET A 422 -22.847 -6.663 -9.730 1.00 51.81 N ANISOU 588 N MET A 422 4957 9384 5343 871 935 -445 N ATOM 589 CA MET A 422 -23.641 -7.877 -9.578 1.00 54.03 C ANISOU 589 CA MET A 422 5185 9818 5528 906 860 -330 C ATOM 590 C MET A 422 -25.124 -7.592 -9.769 1.00 66.01 C ANISOU 590 C MET A 422 6708 11307 7065 880 916 -185 C ATOM 591 O MET A 422 -25.854 -8.431 -10.310 1.00 84.52 O ANISOU 591 O MET A 422 9006 13727 9380 889 871 -80 O ATOM 592 CB MET A 422 -23.395 -8.498 -8.203 1.00 48.43 C ANISOU 592 CB MET A 422 4431 9274 4698 952 808 -335 C ATOM 593 CG MET A 422 -24.220 -9.744 -7.930 1.00 47.96 C ANISOU 593 CG MET A 422 4304 9391 4527 982 754 -186 C ATOM 594 SD MET A 422 -24.594 -9.944 -6.180 1.00 56.19 S ANISOU 594 SD MET A 422 5321 10598 5429 1012 773 -106 S ATOM 595 CE MET A 422 -25.511 -8.439 -5.860 1.00 55.88 C ANISOU 595 CE MET A 422 5343 10412 5479 957 900 -78 C ATOM 596 N LYS A 423 -25.585 -6.414 -9.340 1.00 63.78 N ANISOU 596 N LYS A 423 6469 10929 6834 855 1009 -185 N ATOM 597 CA LYS A 423 -26.996 -6.068 -9.486 1.00 65.98 C ANISOU 597 CA LYS A 423 6744 11191 7134 842 1059 -70 C ATOM 598 C LYS A 423 -27.393 -5.962 -10.952 1.00 59.48 C ANISOU 598 C LYS A 423 5936 10285 6378 834 1063 -42 C ATOM 599 O LYS A 423 -28.474 -6.419 -11.344 1.00 56.00 O ANISOU 599 O LYS A 423 5449 9905 5924 839 1042 70 O ATOM 600 CB LYS A 423 -27.293 -4.757 -8.757 1.00 74.99 C ANISOU 600 CB LYS A 423 7927 12254 8312 837 1155 -108 C ATOM 601 CG LYS A 423 -28.063 -4.919 -7.455 1.00 77.04 C ANISOU 601 CG LYS A 423 8148 12639 8486 857 1169 -35 C ATOM 602 CD LYS A 423 -28.400 -3.564 -6.849 1.00 67.54 C ANISOU 602 CD LYS A 423 6983 11363 7315 869 1263 -87 C ATOM 603 CE LYS A 423 -29.281 -3.705 -5.618 1.00 64.18 C ANISOU 603 CE LYS A 423 6516 11073 6797 897 1286 -11 C ATOM 604 NZ LYS A 423 -29.622 -2.381 -5.028 1.00 68.79 N ANISOU 604 NZ LYS A 423 7131 11605 7402 926 1374 -75 N ATOM 605 N MET A 424 -26.536 -5.356 -11.778 1.00 53.20 N ANISOU 605 N MET A 424 5197 9364 5651 822 1095 -139 N ATOM 606 CA MET A 424 -26.853 -5.204 -13.195 1.00 54.33 C ANISOU 606 CA MET A 424 5362 9443 5839 825 1106 -115 C ATOM 607 C MET A 424 -26.964 -6.555 -13.888 1.00 52.96 C ANISOU 607 C MET A 424 5131 9387 5606 859 1001 -64 C ATOM 608 O MET A 424 -27.851 -6.760 -14.726 1.00 42.81 O ANISOU 608 O MET A 424 3822 8126 4317 882 984 14 O ATOM 609 CB MET A 424 -25.799 -4.336 -13.882 1.00 63.44 C ANISOU 609 CB MET A 424 6582 10456 7065 802 1178 -219 C ATOM 610 CG MET A 424 -25.922 -2.854 -13.580 1.00 60.01 C ANISOU 610 CG MET A 424 6202 9899 6700 777 1299 -252 C ATOM 611 SD MET A 424 -27.551 -2.209 -14.006 1.00 55.35 S ANISOU 611 SD MET A 424 5616 9295 6119 801 1341 -157 S ATOM 612 CE MET A 424 -27.689 -2.731 -15.712 1.00 47.13 C ANISOU 612 CE MET A 424 4581 8261 5066 827 1302 -117 C ATOM 613 N HIS A 425 -26.064 -7.485 -13.559 1.00 62.71 N ANISOU 613 N HIS A 425 6332 10709 6787 876 925 -115 N ATOM 614 CA HIS A 425 -26.137 -8.826 -14.131 1.00 61.50 C ANISOU 614 CA HIS A 425 6111 10689 6567 924 820 -77 C ATOM 615 C HIS A 425 -27.462 -9.497 -13.797 1.00 69.43 C ANISOU 615 C HIS A 425 7034 11817 7529 926 789 80 C ATOM 616 O HIS A 425 -28.022 -10.231 -14.620 1.00 76.24 O ANISOU 616 O HIS A 425 7836 12756 8375 958 732 148 O ATOM 617 CB HIS A 425 -24.965 -9.667 -13.630 1.00 41.48 C ANISOU 617 CB HIS A 425 3544 8244 3972 956 742 -171 C ATOM 618 CG HIS A 425 -25.208 -11.142 -13.700 1.00 52.38 C ANISOU 618 CG HIS A 425 4830 9806 5267 1016 629 -115 C ATOM 619 ND1 HIS A 425 -25.434 -11.804 -14.888 1.00 62.79 N ANISOU 619 ND1 HIS A 425 6112 11165 6578 1069 566 -105 N ATOM 620 CD2 HIS A 425 -25.266 -12.083 -12.728 1.00 61.95 C ANISOU 620 CD2 HIS A 425 5964 11179 6397 1041 570 -62 C ATOM 621 CE1 HIS A 425 -25.618 -13.090 -14.645 1.00 65.96 C ANISOU 621 CE1 HIS A 425 6406 11732 6923 1124 461 -53 C ATOM 622 NE2 HIS A 425 -25.521 -13.285 -13.342 1.00 69.15 N ANISOU 622 NE2 HIS A 425 6780 12214 7279 1103 467 -15 N ATOM 623 N ILE A 426 -27.979 -9.258 -12.591 1.00 64.20 N ANISOU 623 N ILE A 426 6356 11186 6850 893 830 143 N ATOM 624 CA ILE A 426 -29.286 -9.791 -12.225 1.00 58.78 C ANISOU 624 CA ILE A 426 5582 10613 6138 875 825 309 C ATOM 625 C ILE A 426 -30.384 -9.111 -13.034 1.00 68.43 C ANISOU 625 C ILE A 426 6808 11764 7428 870 868 362 C ATOM 626 O ILE A 426 -31.358 -9.752 -13.448 1.00 79.60 O ANISOU 626 O ILE A 426 8129 13270 8845 867 831 484 O ATOM 627 CB ILE A 426 -29.514 -9.633 -10.710 1.00 64.87 C ANISOU 627 CB ILE A 426 6343 11441 6862 848 871 356 C ATOM 628 CG1 ILE A 426 -28.424 -10.364 -9.924 1.00 47.36 C ANISOU 628 CG1 ILE A 426 4115 9325 4556 873 819 305 C ATOM 629 CG2 ILE A 426 -30.888 -10.151 -10.312 1.00 88.35 C ANISOU 629 CG2 ILE A 426 9218 14532 9819 810 883 542 C ATOM 630 CD1 ILE A 426 -28.470 -11.864 -10.074 1.00 40.84 C ANISOU 630 CD1 ILE A 426 3180 8678 3661 888 729 409 C ATOM 631 N LEU A 427 -30.235 -7.810 -13.290 1.00 71.38 N ANISOU 631 N LEU A 427 7274 11984 7863 870 944 274 N ATOM 632 CA LEU A 427 -31.316 -7.034 -13.888 1.00 79.69 C ANISOU 632 CA LEU A 427 8328 12984 8965 881 991 319 C ATOM 633 C LEU A 427 -31.476 -7.318 -15.378 1.00 78.32 C ANISOU 633 C LEU A 427 8144 12816 8800 925 946 331 C ATOM 634 O LEU A 427 -32.604 -7.458 -15.865 1.00 82.96 O ANISOU 634 O LEU A 427 8661 13464 9396 947 930 423 O ATOM 635 CB LEU A 427 -31.071 -5.542 -13.656 1.00 83.03 C ANISOU 635 CB LEU A 427 8845 13259 9443 874 1090 226 C ATOM 636 CG LEU A 427 -32.111 -4.580 -14.236 1.00 93.68 C ANISOU 636 CG LEU A 427 10200 14559 10834 903 1146 254 C ATOM 637 CD1 LEU A 427 -33.488 -4.873 -13.663 1.00102.34 C ANISOU 637 CD1 LEU A 427 11197 15772 11915 907 1141 367 C ATOM 638 CD2 LEU A 427 -31.714 -3.133 -13.980 1.00 94.78 C ANISOU 638 CD2 LEU A 427 10426 14562 11024 897 1245 156 C ATOM 639 N GLN A 428 -30.370 -7.403 -16.119 1.00 73.61 N ANISOU 639 N GLN A 428 7606 12166 8197 945 925 236 N ATOM 640 CA GLN A 428 -30.441 -7.508 -17.570 1.00 71.29 C ANISOU 640 CA GLN A 428 7320 11874 7894 1005 896 231 C ATOM 641 C GLN A 428 -30.377 -8.938 -18.088 1.00 70.35 C ANISOU 641 C GLN A 428 7112 11898 7719 1052 781 261 C ATOM 642 O GLN A 428 -30.720 -9.169 -19.253 1.00 69.25 O ANISOU 642 O GLN A 428 6953 11799 7562 1122 740 275 O ATOM 643 CB GLN A 428 -29.311 -6.697 -18.217 1.00 75.02 C ANISOU 643 CB GLN A 428 7903 12210 8391 1003 957 113 C ATOM 644 CG GLN A 428 -29.348 -5.206 -17.905 1.00 71.96 C ANISOU 644 CG GLN A 428 7593 11678 8070 963 1076 79 C ATOM 645 CD GLN A 428 -30.560 -4.508 -18.497 1.00 74.06 C ANISOU 645 CD GLN A 428 7855 11941 8344 1008 1111 149 C ATOM 646 OE1 GLN A 428 -31.133 -4.964 -19.486 1.00 79.83 O ANISOU 646 OE1 GLN A 428 8550 12748 9033 1076 1058 204 O ATOM 647 NE2 GLN A 428 -30.956 -3.395 -17.890 1.00 70.19 N ANISOU 647 NE2 GLN A 428 7394 11376 7899 986 1195 139 N ATOM 648 N LYS A 429 -29.957 -9.900 -17.265 1.00 69.81 N ANISOU 648 N LYS A 429 6987 11920 7619 1031 723 269 N ATOM 649 CA LYS A 429 -29.786 -11.273 -17.718 1.00 68.40 C ANISOU 649 CA LYS A 429 6711 11878 7400 1086 602 280 C ATOM 650 C LYS A 429 -30.732 -12.268 -17.061 1.00 76.21 C ANISOU 650 C LYS A 429 7544 13003 8408 1047 533 437 C ATOM 651 O LYS A 429 -30.838 -13.401 -17.543 1.00 77.44 O ANISOU 651 O LYS A 429 7585 13248 8592 1089 387 472 O ATOM 652 CB LYS A 429 -28.340 -11.738 -17.485 1.00 43.74 C ANISOU 652 CB LYS A 429 3625 8762 4234 1112 561 146 C ATOM 653 CG LYS A 429 -27.332 -11.183 -18.476 1.00 37.10 C ANISOU 653 CG LYS A 429 2890 7818 3390 1152 588 2 C ATOM 654 CD LYS A 429 -25.961 -11.807 -18.261 1.00 48.30 C ANISOU 654 CD LYS A 429 4314 9267 4772 1186 527 -136 C ATOM 655 CE LYS A 429 -24.998 -11.433 -19.373 1.00 43.66 C ANISOU 655 CE LYS A 429 3805 8599 4184 1222 548 -263 C ATOM 656 NZ LYS A 429 -23.647 -12.021 -19.154 1.00 42.64 N ANISOU 656 NZ LYS A 429 3670 8503 4029 1257 485 -410 N ATOM 657 N HIS A 430 -31.419 -11.889 -15.981 1.00130.80 N ANISOU 657 N HIS A 430 14396 21513 13788 -4267 -2635 521 N ATOM 658 CA HIS A 430 -32.298 -12.817 -15.281 1.00120.64 C ANISOU 658 CA HIS A 430 13215 19962 12661 -4365 -2692 255 C ATOM 659 C HIS A 430 -33.700 -12.260 -15.060 1.00113.88 C ANISOU 659 C HIS A 430 12166 18816 12286 -4595 -2841 216 C ATOM 660 O HIS A 430 -34.488 -12.876 -14.334 1.00108.33 O ANISOU 660 O HIS A 430 11499 17861 11802 -4710 -2856 5 O ATOM 661 CB HIS A 430 -31.683 -13.230 -13.939 1.00124.76 C ANISOU 661 CB HIS A 430 13739 20445 13219 -4393 -2442 126 C ATOM 662 CG HIS A 430 -30.457 -14.079 -14.074 1.00134.05 C ANISOU 662 CG HIS A 430 15142 21853 13938 -4167 -2319 103 C ATOM 663 ND1 HIS A 430 -30.487 -15.348 -14.612 1.00136.43 N ANISOU 663 ND1 HIS A 430 15756 22179 13901 -4014 -2418 -46 N ATOM 664 CD2 HIS A 430 -29.166 -13.842 -13.741 1.00134.60 C ANISOU 664 CD2 HIS A 430 15165 22131 13846 -4068 -2108 209 C ATOM 665 CE1 HIS A 430 -29.268 -15.855 -14.606 1.00136.17 C ANISOU 665 CE1 HIS A 430 15860 22362 13516 -3826 -2264 -29 C ATOM 666 NE2 HIS A 430 -28.447 -14.962 -14.082 1.00140.05 N ANISOU 666 NE2 HIS A 430 16132 22966 14114 -3856 -2077 125 N ATOM 667 N THR A 431 -34.032 -11.122 -15.663 1.00116.42 N ANISOU 667 N THR A 431 12285 19161 12788 -4663 -2947 414 N ATOM 668 CA THR A 431 -35.376 -10.563 -15.608 1.00132.56 C ANISOU 668 CA THR A 431 14141 20937 15289 -4866 -3114 395 C ATOM 669 C THR A 431 -35.810 -10.208 -17.022 1.00141.90 C ANISOU 669 C THR A 431 15360 22184 16371 -4803 -3391 536 C ATOM 670 O THR A 431 -35.049 -9.583 -17.768 1.00145.92 O ANISOU 670 O THR A 431 15856 22937 16648 -4689 -3374 748 O ATOM 671 CB THR A 431 -35.437 -9.330 -14.699 1.00134.58 C ANISOU 671 CB THR A 431 14062 21105 15966 -5056 -2949 501 C ATOM 672 OG1 THR A 431 -34.366 -8.439 -15.027 1.00138.06 O ANISOU 672 OG1 THR A 431 14398 21818 16240 -4972 -2832 740 O ATOM 673 CG2 THR A 431 -35.322 -9.736 -13.236 1.00132.90 C ANISOU 673 CG2 THR A 431 13836 20741 15919 -5154 -2716 325 C ATOM 674 N GLU A 432 -37.027 -10.610 -17.389 1.00141.43 N ANISOU 674 N GLU A 432 15350 21897 16489 -4877 -3649 418 N ATOM 675 CA GLU A 432 -37.509 -10.447 -18.758 1.00144.36 C ANISOU 675 CA GLU A 432 15810 22300 16741 -4809 -3955 521 C ATOM 676 C GLU A 432 -38.287 -9.146 -18.939 1.00147.37 C ANISOU 676 C GLU A 432 15888 22558 17547 -4977 -4079 678 C ATOM 677 O GLU A 432 -37.908 -8.297 -19.752 1.00154.51 O ANISOU 677 O GLU A 432 16742 23636 18329 -4915 -4134 902 O ATOM 678 CB GLU A 432 -38.376 -11.649 -19.152 1.00142.47 C ANISOU 678 CB GLU A 432 15813 21881 16438 -4782 -4204 309 C ATOM 679 CG GLU A 432 -37.663 -12.989 -19.061 1.00143.36 C ANISOU 679 CG GLU A 432 16248 22107 16114 -4608 -4106 149 C ATOM 680 CD GLU A 432 -38.561 -14.154 -19.430 1.00145.57 C ANISOU 680 CD GLU A 432 16760 22195 16353 -4592 -4359 -62 C ATOM 681 OE1 GLU A 432 -39.732 -13.913 -19.789 1.00147.34 O ANISOU 681 OE1 GLU A 432 16891 22198 16894 -4715 -4621 -79 O ATOM 682 OE2 GLU A 432 -38.096 -15.312 -19.359 1.00145.15 O ANISOU 682 OE2 GLU A 432 16981 22206 15963 -4458 -4300 -211 O ATOM 683 N ASN A 433 -39.375 -8.977 -18.188 1.00138.65 N ANISOU 683 N ASN A 433 14582 21149 16949 -5189 -4114 565 N ATOM 684 CA ASN A 433 -40.234 -7.799 -18.318 1.00127.35 C ANISOU 684 CA ASN A 433 12855 19565 15968 -5359 -4242 694 C ATOM 685 C ASN A 433 -39.573 -6.627 -17.596 1.00120.05 C ANISOU 685 C ASN A 433 11663 18740 15210 -5439 -3968 858 C ATOM 686 O ASN A 433 -39.966 -6.217 -16.501 1.00100.98 O ANISOU 686 O ASN A 433 9108 16055 13206 -5486 -3722 775 O ATOM 687 CB ASN A 433 -41.628 -8.086 -17.776 1.00125.63 C ANISOU 687 CB ASN A 433 12540 18952 16242 -5510 -4335 504 C ATOM 688 CG ASN A 433 -42.358 -9.140 -18.584 1.00123.63 C ANISOU 688 CG ASN A 433 12506 18606 15860 -5480 -4679 368 C ATOM 689 OD1 ASN A 433 -41.754 -9.853 -19.386 1.00124.52 O ANISOU 689 OD1 ASN A 433 12920 18915 15477 -5282 -4767 366 O ATOM 690 ND2 ASN A 433 -43.666 -9.246 -18.375 1.00117.96 N ANISOU 690 ND2 ASN A 433 11721 17502 15598 -5514 -4745 224 N ATOM 691 N VAL A 434 -38.544 -6.079 -18.237 1.00115.33 N ANISOU 691 N VAL A 434 11098 18441 14282 -5301 -3908 1067 N ATOM 692 CA VAL A 434 -37.789 -4.950 -17.710 1.00114.08 C ANISOU 692 CA VAL A 434 10704 18412 14228 -5353 -3666 1247 C ATOM 693 C VAL A 434 -38.125 -3.717 -18.535 1.00120.07 C ANISOU 693 C VAL A 434 11281 19200 15140 -5399 -3828 1480 C ATOM 694 O VAL A 434 -38.197 -3.783 -19.768 1.00118.70 O ANISOU 694 O VAL A 434 11262 19124 14714 -5279 -4057 1569 O ATOM 695 CB VAL A 434 -36.273 -5.225 -17.723 1.00104.20 C ANISOU 695 CB VAL A 434 9602 17477 12510 -5164 -3441 1316 C ATOM 696 CG1 VAL A 434 -35.521 -4.105 -17.015 1.00100.09 C ANISOU 696 CG1 VAL A 434 8824 17060 12147 -5237 -3186 1480 C ATOM 697 CG2 VAL A 434 -35.977 -6.561 -17.075 1.00 99.83 C ANISOU 697 CG2 VAL A 434 9272 16897 11760 -5094 -3328 1080 C ATOM 698 N ALA A 435 -38.329 -2.593 -17.851 1.00 82.71 N ANISOU 698 N ALA A 435 6473 15246 9707 -1479 235 -1234 N ATOM 699 CA ALA A 435 -38.688 -1.343 -18.510 1.00 92.32 C ANISOU 699 CA ALA A 435 7212 16512 11355 -1129 327 -896 C ATOM 700 C ALA A 435 -37.457 -0.762 -19.195 1.00 88.13 C ANISOU 700 C ALA A 435 6880 15925 10680 -958 351 -882 C ATOM 701 O ALA A 435 -36.556 -0.239 -18.531 1.00 72.87 O ANISOU 701 O ALA A 435 5210 13645 8833 -923 652 -1070 O ATOM 702 CB ALA A 435 -39.273 -0.360 -17.500 1.00 94.31 C ANISOU 702 CB ALA A 435 7193 16456 12185 -946 810 -845 C ATOM 703 N LYS A 436 -37.416 -0.853 -20.522 1.00100.03 N ANISOU 703 N LYS A 436 8279 17765 11964 -866 27 -644 N ATOM 704 CA LYS A 436 -36.356 -0.228 -21.293 1.00 82.98 C ANISOU 704 CA LYS A 436 6221 15604 9703 -659 83 -569 C ATOM 705 C LYS A 436 -36.672 1.250 -21.518 1.00 83.10 C ANISOU 705 C LYS A 436 5847 15523 10203 -215 395 -277 C ATOM 706 O LYS A 436 -37.769 1.733 -21.225 1.00 66.95 O ANISOU 706 O LYS A 436 3417 13466 8555 -56 509 -98 O ATOM 707 CB LYS A 436 -36.164 -0.951 -22.624 1.00 59.66 C ANISOU 707 CB LYS A 436 3384 13025 6257 -732 -370 -408 C ATOM 708 CG LYS A 436 -35.912 -2.442 -22.483 1.00 56.84 C ANISOU 708 CG LYS A 436 3523 12630 5444 -1121 -563 -647 C ATOM 709 CD LYS A 436 -35.940 -3.137 -23.835 1.00 66.76 C ANISOU 709 CD LYS A 436 5011 14052 6302 -1189 -953 -431 C ATOM 710 CE LYS A 436 -35.860 -4.649 -23.680 1.00 77.70 C ANISOU 710 CE LYS A 436 6912 15181 7430 -1508 -996 -596 C ATOM 711 NZ LYS A 436 -35.968 -5.357 -24.987 1.00 58.81 N ANISOU 711 NZ LYS A 436 4848 12734 4764 -1577 -1338 -396 N ATOM 712 N PHE A 437 -35.693 1.975 -22.051 1.00 83.04 N ANISOU 712 N PHE A 437 5964 15412 10175 11 589 -219 N ATOM 713 CA PHE A 437 -35.770 3.423 -22.180 1.00 90.29 C ANISOU 713 CA PHE A 437 6693 16098 11516 455 1017 16 C ATOM 714 C PHE A 437 -35.697 3.822 -23.646 1.00104.25 C ANISOU 714 C PHE A 437 8291 18218 13103 836 831 435 C ATOM 715 O PHE A 437 -34.828 3.342 -24.383 1.00101.38 O ANISOU 715 O PHE A 437 8263 17923 12333 748 631 405 O ATOM 716 CB PHE A 437 -34.644 4.096 -21.391 1.00 77.91 C ANISOU 716 CB PHE A 437 5526 13950 10127 409 1518 -262 C ATOM 717 CG PHE A 437 -34.593 3.688 -19.947 1.00 69.39 C ANISOU 717 CG PHE A 437 4685 12544 9137 70 1638 -594 C ATOM 718 CD1 PHE A 437 -35.758 3.558 -19.209 1.00 78.72 C ANISOU 718 CD1 PHE A 437 5627 13735 10549 33 1688 -566 C ATOM 719 CD2 PHE A 437 -33.383 3.419 -19.332 1.00 55.16 C ANISOU 719 CD2 PHE A 437 3339 10454 7166 -186 1677 -892 C ATOM 720 CE1 PHE A 437 -35.716 3.178 -17.881 1.00 70.12 C ANISOU 720 CE1 PHE A 437 4795 12392 9457 -236 1805 -827 C ATOM 721 CE2 PHE A 437 -33.335 3.037 -18.004 1.00 53.10 C ANISOU 721 CE2 PHE A 437 3312 9971 6890 -456 1711 -1160 C ATOM 722 CZ PHE A 437 -34.503 2.917 -17.278 1.00 56.21 C ANISOU 722 CZ PHE A 437 3513 10394 7450 -477 1788 -1135 C ATOM 723 N HIS A 438 -36.607 4.697 -24.063 1.00116.76 N ANISOU 723 N HIS A 438 9509 19866 14988 1274 890 848 N ATOM 724 CA HIS A 438 -36.596 5.251 -25.406 1.00127.47 C ANISOU 724 CA HIS A 438 10888 21337 16209 1713 722 1312 C ATOM 725 C HIS A 438 -35.704 6.490 -25.462 1.00135.46 C ANISOU 725 C HIS A 438 12260 21790 17419 2047 1339 1333 C ATOM 726 O HIS A 438 -35.298 7.047 -24.440 1.00142.41 O ANISOU 726 O HIS A 438 13186 22316 18605 1991 1901 1056 O ATOM 727 CB HIS A 438 -38.015 5.596 -25.859 1.00130.65 C ANISOU 727 CB HIS A 438 10694 22106 16843 2069 444 1807 C ATOM 728 CG HIS A 438 -38.890 4.400 -26.074 1.00131.79 C ANISOU 728 CG HIS A 438 10646 22691 16737 1672 -247 1815 C ATOM 729 ND1 HIS A 438 -39.310 3.589 -25.043 1.00130.97 N ANISOU 729 ND1 HIS A 438 10513 22530 16720 1195 -249 1433 N ATOM 730 CD2 HIS A 438 -39.425 3.880 -27.204 1.00135.64 C ANISOU 730 CD2 HIS A 438 11094 23572 16871 1648 -936 2140 C ATOM 731 CE1 HIS A 438 -40.066 2.619 -25.527 1.00133.20 C ANISOU 731 CE1 HIS A 438 10715 23151 16745 901 -850 1516 C ATOM 732 NE2 HIS A 438 -40.152 2.773 -26.836 1.00136.62 N ANISOU 732 NE2 HIS A 438 11166 23841 16903 1129 -1287 1920 N ATOM 733 N CYS A 439 -35.401 6.923 -26.685 1.00129.85 N ANISOU 733 N CYS A 439 11859 20978 16500 2367 1232 1665 N ATOM 734 CA CYS A 439 -34.531 8.083 -26.829 1.00130.24 C ANISOU 734 CA CYS A 439 12293 20478 16714 2655 1833 1693 C ATOM 735 C CYS A 439 -35.359 9.360 -26.956 1.00147.35 C ANISOU 735 C CYS A 439 14205 22504 19279 3247 2163 2112 C ATOM 736 O CYS A 439 -36.367 9.378 -27.670 1.00158.84 O ANISOU 736 O CYS A 439 15350 24295 20706 3567 1755 2557 O ATOM 737 CB CYS A 439 -33.633 7.932 -28.052 1.00126.53 C ANISOU 737 CB CYS A 439 12394 19871 15812 2697 1678 1809 C ATOM 738 SG CYS A 439 -32.490 9.306 -28.326 1.00128.44 S ANISOU 738 SG CYS A 439 13140 19423 16240 2992 2439 1840 S ATOM 739 N PRO A 440 -34.958 10.434 -26.268 1.00143.98 N ANISOU 739 N PRO A 440 13914 21577 19216 3396 2892 1991 N ATOM 740 CA PRO A 440 -35.708 11.696 -26.379 1.00140.13 C ANISOU 740 CA PRO A 440 13300 20851 19090 3974 3274 2384 C ATOM 741 C PRO A 440 -35.637 12.329 -27.757 1.00138.64 C ANISOU 741 C PRO A 440 13378 20572 18727 4504 3218 2880 C ATOM 742 O PRO A 440 -36.505 13.147 -28.086 1.00144.70 O ANISOU 742 O PRO A 440 13922 21328 19730 5082 3333 3346 O ATOM 743 CB PRO A 440 -35.047 12.595 -25.322 1.00137.31 C ANISOU 743 CB PRO A 440 13404 19792 18976 3708 3905 1957 C ATOM 744 CG PRO A 440 -34.345 11.653 -24.394 1.00135.31 C ANISOU 744 CG PRO A 440 13233 19584 18594 3031 3772 1372 C ATOM 745 CD PRO A 440 -33.900 10.508 -25.248 1.00138.17 C ANISOU 745 CD PRO A 440 13510 20424 18563 2946 3316 1449 C ATOM 746 N HIS A 441 -34.636 11.984 -28.572 1.00131.70 N ANISOU 746 N HIS A 441 13025 19584 17432 4325 3050 2799 N ATOM 747 CA HIS A 441 -34.490 12.565 -29.901 1.00127.97 C ANISOU 747 CA HIS A 441 12964 18937 16720 4769 3008 3231 C ATOM 748 C HIS A 441 -34.298 11.512 -30.987 1.00116.25 C ANISOU 748 C HIS A 441 11735 17779 14656 4576 2302 3321 C ATOM 749 O HIS A 441 -33.904 11.862 -32.106 1.00111.58 O ANISOU 749 O HIS A 441 11661 16970 13766 4839 2300 3593 O ATOM 750 CB HIS A 441 -33.318 13.554 -29.931 1.00131.93 C ANISOU 750 CB HIS A 441 14056 18759 17314 4832 3765 3093 C ATOM 751 CG HIS A 441 -33.437 14.665 -28.935 1.00140.88 C ANISOU 751 CG HIS A 441 15101 19479 18948 4998 4510 3003 C ATOM 752 ND1 HIS A 441 -34.378 15.665 -29.045 1.00150.64 N ANISOU 752 ND1 HIS A 441 16186 20592 20457 5607 4767 3437 N ATOM 753 CD2 HIS A 441 -32.727 14.937 -27.814 1.00139.09 C ANISOU 753 CD2 HIS A 441 15056 18864 18929 4504 4925 2496 C ATOM 754 CE1 HIS A 441 -34.247 16.504 -28.032 1.00151.65 C ANISOU 754 CE1 HIS A 441 16539 20212 20870 5344 5249 3144 C ATOM 755 NE2 HIS A 441 -33.252 16.085 -27.271 1.00144.39 N ANISOU 755 NE2 HIS A 441 15819 19134 19906 4676 5313 2574 N ATOM 756 N CYS A 442 -34.565 10.240 -30.695 1.00124.21 N ANISOU 756 N CYS A 442 12468 19260 15466 4118 1743 3099 N ATOM 757 CA CYS A 442 -34.438 9.171 -31.675 1.00136.29 C ANISOU 757 CA CYS A 442 14300 21081 16403 3888 1086 3165 C ATOM 758 C CYS A 442 -35.592 8.196 -31.490 1.00149.75 C ANISOU 758 C CYS A 442 15448 23426 18023 3659 373 3224 C ATOM 759 O CYS A 442 -36.437 8.357 -30.604 1.00141.66 O ANISOU 759 O CYS A 442 13783 22608 17432 3695 433 3214 O ATOM 760 CB CYS A 442 -33.086 8.457 -31.553 1.00137.26 C ANISOU 760 CB CYS A 442 14900 20984 16270 3420 1259 2713 C ATOM 761 SG CYS A 442 -31.645 9.495 -31.895 1.00147.37 S ANISOU 761 SG CYS A 442 16812 21541 17640 3604 2062 2652 S ATOM 762 N ASP A 443 -35.623 7.169 -32.341 1.00164.05 N ANISOU 762 N ASP A 443 17542 25527 19261 3397 -275 3284 N ATOM 763 CA ASP A 443 -36.668 6.154 -32.312 1.00170.87 C ANISOU 763 CA ASP A 443 17964 27000 19958 3090 -1012 3339 C ATOM 764 C ASP A 443 -36.130 4.785 -31.911 1.00159.20 C ANISOU 764 C ASP A 443 16700 25648 18141 2441 -1202 2862 C ATOM 765 O ASP A 443 -36.780 3.766 -32.170 1.00163.19 O ANISOU 765 O ASP A 443 17099 26597 18309 2096 -1855 2888 O ATOM 766 CB ASP A 443 -37.363 6.079 -33.671 1.00185.77 C ANISOU 766 CB ASP A 443 20010 29165 21409 3296 -1712 3860 C ATOM 767 CG ASP A 443 -37.967 7.404 -34.086 1.00198.22 C ANISOU 767 CG ASP A 443 21361 30645 23310 3993 -1572 4388 C ATOM 768 OD1 ASP A 443 -38.648 8.035 -33.251 1.00201.81 O ANISOU 768 OD1 ASP A 443 21127 31176 24377 4245 -1287 4464 O ATOM 769 OD2 ASP A 443 -37.752 7.821 -35.243 1.00203.67 O ANISOU 769 OD2 ASP A 443 22607 31146 23631 4310 -1704 4735 O ATOM 770 N THR A 444 -34.959 4.741 -31.287 1.00144.69 N ANISOU 770 N THR A 444 15165 23427 16384 2262 -654 2441 N ATOM 771 CA THR A 444 -34.359 3.499 -30.827 1.00124.19 C ANISOU 771 CA THR A 444 12781 20901 13506 1716 -758 1999 C ATOM 772 C THR A 444 -34.632 3.297 -29.341 1.00110.29 C ANISOU 772 C THR A 444 10482 19254 12168 1456 -552 1637 C ATOM 773 O THR A 444 -34.927 4.240 -28.602 1.00107.26 O ANISOU 773 O THR A 444 9699 18739 12316 1698 -138 1652 O ATOM 774 CB THR A 444 -32.849 3.493 -31.088 1.00116.29 C ANISOU 774 CB THR A 444 12430 19430 12323 1681 -320 1791 C ATOM 775 OG1 THR A 444 -32.283 2.270 -30.601 1.00102.79 O ANISOU 775 OG1 THR A 444 10896 17796 10365 1204 -413 1395 O ATOM 776 CG2 THR A 444 -32.181 4.670 -30.392 1.00113.71 C ANISOU 776 CG2 THR A 444 11992 18675 12539 1913 408 1670 C ATOM 777 N VAL A 445 -34.530 2.042 -28.910 1.00105.21 N ANISOU 777 N VAL A 445 9907 18817 11250 961 -815 1311 N ATOM 778 CA VAL A 445 -34.789 1.650 -27.531 1.00 98.01 C ANISOU 778 CA VAL A 445 8593 18016 10628 653 -674 947 C ATOM 779 C VAL A 445 -33.537 0.982 -26.980 1.00 96.58 C ANISOU 779 C VAL A 445 8835 17588 10273 337 -435 507 C ATOM 780 O VAL A 445 -32.951 0.113 -27.636 1.00 92.46 O ANISOU 780 O VAL A 445 8806 17064 9259 154 -662 458 O ATOM 781 CB VAL A 445 -36.003 0.708 -27.427 1.00 90.22 C ANISOU 781 CB VAL A 445 7229 17553 9498 333 -1239 982 C ATOM 782 CG1 VAL A 445 -36.340 0.435 -25.972 1.00 88.17 C ANISOU 782 CG1 VAL A 445 6567 17353 9581 63 -1000 630 C ATOM 783 CG2 VAL A 445 -37.201 1.299 -28.156 1.00 90.35 C ANISOU 783 CG2 VAL A 445 6802 17871 9657 655 -1584 1490 C ATOM 784 N ILE A 446 -33.130 1.390 -25.777 1.00 94.69 N ANISOU 784 N ILE A 446 8425 17127 10427 280 24 205 N ATOM 785 CA ILE A 446 -31.939 0.862 -25.128 1.00 96.17 C ANISOU 785 CA ILE A 446 8926 17092 10521 5 236 -190 C ATOM 786 C ILE A 446 -32.290 0.461 -23.702 1.00 96.00 C ANISOU 786 C ILE A 446 8628 17161 10688 -309 308 -541 C ATOM 787 O ILE A 446 -33.296 0.895 -23.136 1.00 95.42 O ANISOU 787 O ILE A 446 8197 17126 10933 -247 373 -483 O ATOM 788 CB ILE A 446 -30.775 1.874 -25.140 1.00 90.68 C ANISOU 788 CB ILE A 446 8431 15942 10081 223 754 -216 C ATOM 789 CG1 ILE A 446 -31.169 3.143 -24.383 1.00 96.91 C ANISOU 789 CG1 ILE A 446 8882 16535 11403 423 1182 -202 C ATOM 790 CG2 ILE A 446 -30.381 2.209 -26.567 1.00 81.85 C ANISOU 790 CG2 ILE A 446 7667 14691 8741 521 736 121 C ATOM 791 CD1 ILE A 446 -30.021 4.095 -24.162 1.00 95.45 C ANISOU 791 CD1 ILE A 446 8897 15889 11479 508 1706 -307 C ATOM 792 N ALA A 447 -31.435 -0.380 -23.121 1.00 96.55 N ANISOU 792 N ALA A 447 8972 17156 10557 -620 312 -884 N ATOM 793 CA ALA A 447 -31.709 -0.979 -21.817 1.00 91.29 C ANISOU 793 CA ALA A 447 8483 16269 9933 -894 282 -1180 C ATOM 794 C ALA A 447 -31.187 -0.122 -20.666 1.00 81.37 C ANISOU 794 C ALA A 447 7353 14472 9092 -857 629 -1351 C ATOM 795 O ALA A 447 -31.953 0.271 -19.780 1.00 73.26 O ANISOU 795 O ALA A 447 6221 13275 8340 -859 758 -1381 O ATOM 796 CB ALA A 447 -31.104 -2.386 -21.753 1.00 84.56 C ANISOU 796 CB ALA A 447 8038 15475 8618 -1168 114 -1385 C ATOM 797 N ARG A 448 -29.891 0.173 -20.666 1.00 82.85 N ANISOU 797 N ARG A 448 7771 14377 9333 -842 781 -1434 N ATOM 798 CA ARG A 448 -29.241 0.839 -19.548 1.00 68.84 C ANISOU 798 CA ARG A 448 6166 12124 7867 -904 1008 -1599 C ATOM 799 C ARG A 448 -29.141 2.341 -19.783 1.00 46.09 C ANISOU 799 C ARG A 448 3173 8957 5382 -643 1408 -1395 C ATOM 800 O ARG A 448 -29.014 2.805 -20.920 1.00 46.78 O ANISOU 800 O ARG A 448 3160 9134 5482 -403 1530 -1166 O ATOM 801 CB ARG A 448 -27.841 0.266 -19.316 1.00 70.28 C ANISOU 801 CB ARG A 448 6625 12173 7904 -1072 907 -1791 C ATOM 802 CG ARG A 448 -27.809 -1.231 -19.050 1.00 65.44 C ANISOU 802 CG ARG A 448 6185 11815 6864 -1299 587 -2001 C ATOM 803 CD ARG A 448 -26.380 -1.737 -18.909 1.00 53.57 C ANISOU 803 CD ARG A 448 4867 10181 5306 -1393 517 -2110 C ATOM 804 NE ARG A 448 -25.621 -0.965 -17.928 1.00 45.25 N ANISOU 804 NE ARG A 448 3874 8803 4516 -1463 671 -2261 N ATOM 805 CZ ARG A 448 -24.395 -1.275 -17.518 1.00 40.25 C ANISOU 805 CZ ARG A 448 3363 8006 3922 -1503 662 -2294 C ATOM 806 NH1 ARG A 448 -23.784 -2.350 -17.998 1.00 41.60 N ANISOU 806 NH1 ARG A 448 3607 8185 4013 -1417 547 -2099 N ATOM 807 NH2 ARG A 448 -23.779 -0.513 -16.624 1.00 35.47 N ANISOU 807 NH2 ARG A 448 2786 7211 3482 -1614 800 -2479 N ATOM 808 N LYS A 449 -29.200 3.099 -18.684 1.00 45.88 N ANISOU 808 N LYS A 449 3205 8603 5624 -693 1644 -1489 N ATOM 809 CA LYS A 449 -28.908 4.527 -18.751 1.00 52.12 C ANISOU 809 CA LYS A 449 3992 9083 6727 -492 2069 -1339 C ATOM 810 C LYS A 449 -27.441 4.777 -19.071 1.00 59.70 C ANISOU 810 C LYS A 449 5141 9856 7686 -555 2126 -1386 C ATOM 811 O LYS A 449 -27.105 5.803 -19.675 1.00 57.71 O ANISOU 811 O LYS A 449 4885 9444 7598 -345 2446 -1202 O ATOM 812 CB LYS A 449 -29.284 5.209 -17.435 1.00 50.16 C ANISOU 812 CB LYS A 449 3819 8577 6665 -584 2302 -1472 C ATOM 813 CG LYS A 449 -30.775 5.266 -17.160 1.00 51.89 C ANISOU 813 CG LYS A 449 3801 8917 6996 -432 2400 -1335 C ATOM 814 CD LYS A 449 -31.062 5.879 -15.798 1.00 53.35 C ANISOU 814 CD LYS A 449 4136 8822 7314 -545 2673 -1505 C ATOM 815 CE LYS A 449 -30.499 7.287 -15.694 1.00 55.65 C ANISOU 815 CE LYS A 449 4589 8779 7778 -449 3072 -1487 C ATOM 816 NZ LYS A 449 -30.739 7.878 -14.348 1.00 57.51 N ANISOU 816 NZ LYS A 449 5051 8677 8121 -629 3361 -1722 N ATOM 817 N SER A 450 -26.558 3.861 -18.665 1.00 50.68 N ANISOU 817 N SER A 450 4149 8742 6366 -829 1843 -1622 N ATOM 818 CA SER A 450 -25.151 3.966 -19.036 1.00 54.22 C ANISOU 818 CA SER A 450 4693 9059 6847 -879 1885 -1634 C ATOM 819 C SER A 450 -24.987 3.964 -20.549 1.00 70.62 C ANISOU 819 C SER A 450 6723 11243 8865 -606 1984 -1353 C ATOM 820 O SER A 450 -24.137 4.680 -21.093 1.00 82.66 O ANISOU 820 O SER A 450 8290 12578 10539 -506 2244 -1233 O ATOM 821 CB SER A 450 -24.360 2.821 -18.405 1.00 45.63 C ANISOU 821 CB SER A 450 3714 8064 5559 -1155 1557 -1898 C ATOM 822 OG SER A 450 -24.684 2.675 -17.033 1.00 43.20 O ANISOU 822 OG SER A 450 3485 7716 5213 -1402 1464 -2189 O ATOM 823 N ASP A 451 -25.792 3.159 -21.246 1.00 72.74 N ANISOU 823 N ASP A 451 6918 11844 8874 -510 1787 -1270 N ATOM 824 CA ASP A 451 -25.810 3.208 -22.703 1.00 74.05 C ANISOU 824 CA ASP A 451 7063 12181 8892 -253 1900 -1030 C ATOM 825 C ASP A 451 -26.471 4.484 -23.206 1.00 71.95 C ANISOU 825 C ASP A 451 6658 11841 8839 56 2256 -802 C ATOM 826 O ASP A 451 -26.066 5.024 -24.241 1.00 82.43 O ANISOU 826 O ASP A 451 8057 13114 10148 292 2526 -614 O ATOM 827 CB ASP A 451 -26.531 1.979 -23.258 1.00 80.28 C ANISOU 827 CB ASP A 451 7801 13478 9223 -285 1536 -1018 C ATOM 828 CG ASP A 451 -25.957 0.678 -22.729 1.00 70.60 C ANISOU 828 CG ASP A 451 6746 12312 7766 -566 1232 -1246 C ATOM 829 OD1 ASP A 451 -24.728 0.613 -22.519 1.00 65.04 O ANISOU 829 OD1 ASP A 451 6190 11338 7185 -628 1311 -1315 O ATOM 830 OD2 ASP A 451 -26.736 -0.277 -22.522 1.00 63.70 O ANISOU 830 OD2 ASP A 451 5830 11777 6595 -719 925 -1342 O ATOM 831 N LEU A 452 -27.484 4.977 -22.490 1.00 64.80 N ANISOU 831 N LEU A 452 5580 10917 8126 89 2305 -804 N ATOM 832 CA LEU A 452 -28.130 6.225 -22.879 1.00 68.20 C ANISOU 832 CA LEU A 452 5864 11249 8800 433 2693 -577 C ATOM 833 C LEU A 452 -27.189 7.409 -22.710 1.00 81.06 C ANISOU 833 C LEU A 452 7693 12485 10620 505 3100 -532 C ATOM 834 O LEU A 452 -27.227 8.358 -23.503 1.00 87.20 O ANISOU 834 O LEU A 452 8484 13210 11439 743 3367 -450 O ATOM 835 CB LEU A 452 -29.409 6.427 -22.064 1.00 66.97 C ANISOU 835 CB LEU A 452 5472 11146 8829 467 2687 -567 C ATOM 836 CG LEU A 452 -30.212 7.706 -22.309 1.00 61.75 C ANISOU 836 CG LEU A 452 4625 10360 8476 830 3092 -390 C ATOM 837 CD1 LEU A 452 -30.546 7.864 -23.783 1.00 62.58 C ANISOU 837 CD1 LEU A 452 4627 10784 8368 1299 2980 64 C ATOM 838 CD2 LEU A 452 -31.481 7.704 -21.469 1.00 64.52 C ANISOU 838 CD2 LEU A 452 4714 10764 9036 839 3080 -393 C ATOM 839 N GLY A 453 -26.336 7.373 -21.685 1.00 77.78 N ANISOU 839 N GLY A 453 7450 11843 10259 165 3007 -778 N ATOM 840 CA GLY A 453 -25.382 8.452 -21.494 1.00 82.09 C ANISOU 840 CA GLY A 453 8176 12041 10973 74 3277 -858 C ATOM 841 C GLY A 453 -24.367 8.536 -22.618 1.00 72.36 C ANISOU 841 C GLY A 453 7045 10749 9699 154 3388 -750 C ATOM 842 O GLY A 453 -24.076 9.622 -23.125 1.00 71.49 O ANISOU 842 O GLY A 453 7074 10352 9735 272 3724 -670 O ATOM 843 N VAL A 454 -23.821 7.389 -23.028 1.00 75.54 N ANISOU 843 N VAL A 454 7442 11335 9926 90 3148 -741 N ATOM 844 CA VAL A 454 -22.846 7.376 -24.114 1.00 76.60 C ANISOU 844 CA VAL A 454 7693 11410 10002 177 3287 -631 C ATOM 845 C VAL A 454 -23.511 7.516 -25.478 1.00 90.88 C ANISOU 845 C VAL A 454 9570 13324 11638 521 3467 -417 C ATOM 846 O VAL A 454 -22.846 7.905 -26.446 1.00 97.60 O ANISOU 846 O VAL A 454 10656 13923 12506 649 3710 -271 O ATOM 847 CB VAL A 454 -21.991 6.098 -24.054 1.00 53.08 C ANISOU 847 CB VAL A 454 4729 8529 6910 3 3026 -701 C ATOM 848 CG1 VAL A 454 -22.769 4.900 -24.583 1.00 49.15 C ANISOU 848 CG1 VAL A 454 4253 8321 6100 92 2810 -660 C ATOM 849 CG2 VAL A 454 -20.684 6.288 -24.816 1.00 52.10 C ANISOU 849 CG2 VAL A 454 4700 8249 6847 19 3226 -626 C ATOM 850 N HIS A 455 -24.807 7.214 -25.583 1.00 92.08 N ANISOU 850 N HIS A 455 9572 13736 11678 686 3377 -340 N ATOM 851 CA HIS A 455 -25.513 7.405 -26.846 1.00 89.98 C ANISOU 851 CA HIS A 455 9449 13523 11215 1151 3433 97 C ATOM 852 C HIS A 455 -25.583 8.882 -27.209 1.00 86.54 C ANISOU 852 C HIS A 455 9170 12671 11041 1440 3870 298 C ATOM 853 O HIS A 455 -25.150 9.290 -28.293 1.00 88.54 O ANISOU 853 O HIS A 455 9749 12693 11200 1697 4113 557 O ATOM 854 CB HIS A 455 -26.915 6.801 -26.760 1.00 95.55 C ANISOU 854 CB HIS A 455 9932 14653 11718 1225 2936 199 C ATOM 855 CG HIS A 455 -27.782 7.116 -27.938 1.00112.18 C ANISOU 855 CG HIS A 455 12164 16836 13625 1648 2769 644 C ATOM 856 ND1 HIS A 455 -27.607 6.525 -29.171 1.00117.11 N ANISOU 856 ND1 HIS A 455 13156 17529 13812 1755 2512 869 N ATOM 857 CD2 HIS A 455 -28.829 7.964 -28.072 1.00123.25 C ANISOU 857 CD2 HIS A 455 13394 18244 15189 2004 2816 928 C ATOM 858 CE1 HIS A 455 -28.511 6.994 -30.013 1.00126.17 C ANISOU 858 CE1 HIS A 455 14362 18741 14835 2130 2347 1266 C ATOM 859 NE2 HIS A 455 -29.264 7.869 -29.372 1.00132.40 N ANISOU 859 NE2 HIS A 455 14789 19511 16008 2309 2522 1324 N ATOM 860 N LEU A 456 -26.114 9.704 -26.301 1.00 86.00 N ANISOU 860 N LEU A 456 8953 12461 11264 1389 3968 177 N ATOM 861 CA LEU A 456 -26.224 11.135 -26.556 1.00 95.37 C ANISOU 861 CA LEU A 456 10347 13216 12673 1652 4369 365 C ATOM 862 C LEU A 456 -24.863 11.801 -26.720 1.00 95.93 C ANISOU 862 C LEU A 456 10737 12845 12868 1445 4644 256 C ATOM 863 O LEU A 456 -24.789 12.906 -27.269 1.00100.61 O ANISOU 863 O LEU A 456 11607 13040 13581 1688 5024 469 O ATOM 864 CB LEU A 456 -26.998 11.808 -25.422 1.00101.47 C ANISOU 864 CB LEU A 456 10959 13905 13692 1601 4440 236 C ATOM 865 CG LEU A 456 -28.311 11.140 -25.008 1.00106.43 C ANISOU 865 CG LEU A 456 11190 14965 14285 1709 4156 283 C ATOM 866 CD1 LEU A 456 -28.921 11.852 -23.812 1.00111.53 C ANISOU 866 CD1 LEU A 456 11767 15437 15171 1622 4304 123 C ATOM 867 CD2 LEU A 456 -29.292 11.101 -26.168 1.00113.00 C ANISOU 867 CD2 LEU A 456 11878 16061 14996 2299 4096 816 C ATOM 868 N ARG A 457 -23.790 11.159 -26.254 1.00 91.77 N ANISOU 868 N ARG A 457 10159 12384 12326 1027 4463 -30 N ATOM 869 CA ARG A 457 -22.458 11.739 -26.390 1.00 94.80 C ANISOU 869 CA ARG A 457 10748 12391 12881 826 4703 -95 C ATOM 870 C ARG A 457 -22.015 11.776 -27.849 1.00108.68 C ANISOU 870 C ARG A 457 12796 13976 14521 1094 4918 185 C ATOM 871 O ARG A 457 -21.511 12.798 -28.328 1.00119.96 O ANISOU 871 O ARG A 457 14501 14964 16114 1169 5307 303 O ATOM 872 CB ARG A 457 -21.456 10.953 -25.542 1.00 87.82 C ANISOU 872 CB ARG A 457 9677 11665 12028 393 4428 -382 C ATOM 873 CG ARG A 457 -21.504 11.273 -24.055 1.00 85.10 C ANISOU 873 CG ARG A 457 9218 11256 11859 75 4360 -644 C ATOM 874 CD ARG A 457 -20.789 10.207 -23.237 1.00 88.86 C ANISOU 874 CD ARG A 457 9508 11957 12297 -262 3997 -859 C ATOM 875 NE ARG A 457 -19.405 10.011 -23.662 1.00 99.02 N ANISOU 875 NE ARG A 457 10790 13149 13683 -403 4046 -861 N ATOM 876 CZ ARG A 457 -18.347 10.472 -23.002 1.00106.04 C ANISOU 876 CZ ARG A 457 11639 13807 14844 -749 4153 -1047 C ATOM 877 NH1 ARG A 457 -18.510 11.154 -21.877 1.00107.29 N ANISOU 877 NH1 ARG A 457 11829 13773 15163 -1022 4233 -1282 N ATOM 878 NH2 ARG A 457 -17.125 10.245 -23.465 1.00106.95 N ANISOU 878 NH2 ARG A 457 11683 13882 15072 -835 4204 -1009 N ATOM 879 N LYS A 458 -22.197 10.670 -28.573 1.00104.08 N ANISOU 879 N LYS A 458 12221 13696 13626 1239 4706 305 N ATOM 880 CA LYS A 458 -21.734 10.566 -29.950 1.00104.46 C ANISOU 880 CA LYS A 458 12644 13565 13483 1490 4910 581 C ATOM 881 C LYS A 458 -22.854 10.584 -30.981 1.00 99.82 C ANISOU 881 C LYS A 458 12301 13080 12548 2032 4970 1001 C ATOM 882 O LYS A 458 -22.562 10.603 -32.182 1.00104.84 O ANISOU 882 O LYS A 458 13374 13527 12935 2297 5171 1277 O ATOM 883 CB LYS A 458 -20.900 9.290 -30.136 1.00107.21 C ANISOU 883 CB LYS A 458 12967 14109 13658 1282 4691 464 C ATOM 884 CG LYS A 458 -19.578 9.300 -29.385 1.00109.36 C ANISOU 884 CG LYS A 458 13030 14277 14244 872 4677 184 C ATOM 885 CD LYS A 458 -18.747 8.067 -29.705 1.00111.89 C ANISOU 885 CD LYS A 458 13345 14755 14411 776 4521 148 C ATOM 886 CE LYS A 458 -17.405 8.106 -28.990 1.00117.24 C ANISOU 886 CE LYS A 458 13769 15356 15422 450 4523 -42 C ATOM 887 NZ LYS A 458 -16.558 6.928 -29.323 1.00115.33 N ANISOU 887 NZ LYS A 458 13508 15243 15071 422 4423 -32 N ATOM 888 N GLN A 459 -24.116 10.574 -30.557 1.00 93.69 N ANISOU 888 N GLN A 459 11261 12620 11718 2234 4797 1091 N ATOM 889 CA GLN A 459 -25.241 10.673 -31.479 1.00 95.47 C ANISOU 889 CA GLN A 459 11654 12998 11621 2715 4577 1518 C ATOM 890 C GLN A 459 -25.886 12.052 -31.474 1.00 95.11 C ANISOU 890 C GLN A 459 11632 12679 11828 3099 4932 1752 C ATOM 891 O GLN A 459 -26.323 12.530 -32.526 1.00 95.46 O ANISOU 891 O GLN A 459 12017 12598 11657 3539 4940 2156 O ATOM 892 CB GLN A 459 -26.301 9.618 -31.147 1.00 93.00 C ANISOU 892 CB GLN A 459 11003 13255 11077 2622 3866 1494 C ATOM 893 CG GLN A 459 -27.336 9.408 -32.240 1.00 96.80 C ANISOU 893 CG GLN A 459 11670 13970 11140 2977 3390 1921 C ATOM 894 CD GLN A 459 -26.785 8.627 -33.416 1.00100.12 C ANISOU 894 CD GLN A 459 12640 14358 11041 2961 3215 2047 C ATOM 895 OE1 GLN A 459 -25.800 7.900 -33.286 1.00 93.97 O ANISOU 895 OE1 GLN A 459 11981 13523 10199 2653 3325 1790 O ATOM 896 NE2 GLN A 459 -27.419 8.773 -34.574 1.00110.45 N ANISOU 896 NE2 GLN A 459 14315 15686 11965 3307 2948 2464 N ATOM 897 N HIS A 460 -25.954 12.702 -30.317 1.00 98.30 N ANISOU 897 N HIS A 460 11749 12947 12653 2927 5187 1510 N ATOM 898 CA HIS A 460 -26.565 14.021 -30.210 1.00 97.42 C ANISOU 898 CA HIS A 460 11714 12510 12790 3248 5514 1706 C ATOM 899 C HIS A 460 -25.608 15.017 -29.565 1.00 91.11 C ANISOU 899 C HIS A 460 11132 11155 12330 2840 5850 1407 C ATOM 900 O HIS A 460 -25.309 16.065 -30.138 1.00 85.60 O ANISOU 900 O HIS A 460 10834 9985 11706 3044 6275 1603 O ATOM 901 CB HIS A 460 -27.865 13.944 -29.408 1.00 94.91 C ANISOU 901 CB HIS A 460 10916 12536 12609 3388 5286 1740 C ATOM 902 CG HIS A 460 -28.825 12.914 -29.916 1.00104.59 C ANISOU 902 CG HIS A 460 11881 14349 13509 3566 4615 1975 C ATOM 903 ND1 HIS A 460 -29.772 13.189 -30.878 1.00112.56 N ANISOU 903 ND1 HIS A 460 12947 15484 14336 4084 4358 2472 N ATOM 904 CD2 HIS A 460 -28.980 11.607 -29.599 1.00104.75 C ANISOU 904 CD2 HIS A 460 11629 14842 13329 3213 4048 1769 C ATOM 905 CE1 HIS A 460 -30.470 12.096 -31.131 1.00115.41 C ANISOU 905 CE1 HIS A 460 13059 16388 14403 3999 3638 2552 C ATOM 906 NE2 HIS A 460 -30.010 11.122 -30.367 1.00120.17 N ANISOU 906 NE2 HIS A 460 13481 17192 14986 3471 3468 2122 N TER 907 HIS A 460 ATOM 908 O5' DC B 1 -25.955 -6.392 -19.593 1.00 58.50 O ANISOU 908 O5' DC B 1 5694 11150 5382 1476 -120 -1646 O ATOM 909 C5' DC B 1 -25.791 -7.692 -20.149 1.00 62.91 C ANISOU 909 C5' DC B 1 6100 11782 6020 1398 -177 -1831 C ATOM 910 C4' DC B 1 -24.343 -7.936 -20.533 1.00 66.25 C ANISOU 910 C4' DC B 1 6575 12134 6462 1297 -120 -1834 C ATOM 911 O4' DC B 1 -23.961 -7.011 -21.572 1.00 68.41 O ANISOU 911 O4' DC B 1 6968 12466 6557 1357 -79 -1738 O ATOM 912 C3' DC B 1 -23.341 -7.706 -19.416 1.00 60.32 C ANISOU 912 C3' DC B 1 5917 11192 5809 1204 -37 -1754 C ATOM 913 O3' DC B 1 -23.182 -8.900 -18.661 1.00 52.01 O ANISOU 913 O3' DC B 1 4781 10054 4928 1133 -60 -1863 O ATOM 914 C2' DC B 1 -22.061 -7.355 -20.174 1.00 59.02 C ANISOU 914 C2' DC B 1 5826 11025 5573 1143 29 -1732 C ATOM 915 C1' DC B 1 -22.582 -6.710 -21.466 1.00 60.02 C ANISOU 915 C1' DC B 1 6010 11283 5510 1244 22 -1687 C ATOM 916 N1 DC B 1 -22.414 -5.222 -21.521 1.00 50.67 N ANISOU 916 N1 DC B 1 5049 10025 4179 1279 133 -1510 N ATOM 917 C2 DC B 1 -21.137 -4.670 -21.681 1.00 44.50 C ANISOU 917 C2 DC B 1 4397 9147 3366 1159 266 -1471 C ATOM 918 O2 DC B 1 -20.158 -5.422 -21.762 1.00 40.15 O ANISOU 918 O2 DC B 1 3749 8598 2909 1045 267 -1583 O ATOM 919 N3 DC B 1 -21.008 -3.320 -21.737 1.00 44.84 N ANISOU 919 N3 DC B 1 4675 9092 3272 1168 401 -1325 N ATOM 920 C4 DC B 1 -22.086 -2.541 -21.646 1.00 41.65 C ANISOU 920 C4 DC B 1 4383 8683 2761 1321 391 -1202 C ATOM 921 N4 DC B 1 -21.907 -1.217 -21.707 1.00 42.60 N ANISOU 921 N4 DC B 1 4771 8673 2742 1329 547 -1056 N ATOM 922 C5 DC B 1 -23.394 -3.084 -21.488 1.00 41.44 C ANISOU 922 C5 DC B 1 4200 8781 2765 1471 232 -1238 C ATOM 923 C6 DC B 1 -23.511 -4.415 -21.434 1.00 40.76 C ANISOU 923 C6 DC B 1 3876 8793 2819 1428 116 -1402 C ATOM 924 P DA B 2 -23.263 -8.865 -17.057 1.00 55.12 P ANISOU 924 P DA B 2 5223 10275 5445 1111 -22 -1795 P ATOM 925 OP1 DA B 2 -23.569 -10.241 -16.606 1.00 53.09 O ANISOU 925 OP1 DA B 2 4893 9943 5334 1076 -42 -1921 O ATOM 926 OP2 DA B 2 -24.150 -7.748 -16.665 1.00 55.44 O ANISOU 926 OP2 DA B 2 5325 10322 5416 1181 -5 -1670 O ATOM 927 O5' DA B 2 -21.774 -8.488 -16.606 1.00 56.80 O ANISOU 927 O5' DA B 2 5511 10400 5672 1052 37 -1738 O ATOM 928 C5' DA B 2 -20.727 -9.442 -16.737 1.00 44.35 C ANISOU 928 C5' DA B 2 3885 8806 4161 1008 22 -1843 C ATOM 929 C4' DA B 2 -19.390 -8.752 -16.932 1.00 39.79 C ANISOU 929 C4' DA B 2 3345 8243 3532 948 74 -1816 C ATOM 930 O4' DA B 2 -19.479 -7.849 -18.060 1.00 51.74 O ANISOU 930 O4' DA B 2 4909 9844 4907 937 119 -1767 O ATOM 931 C3' DA B 2 -18.944 -7.869 -15.781 1.00 49.46 C ANISOU 931 C3' DA B 2 4642 9377 4772 919 132 -1722 C ATOM 932 O3' DA B 2 -18.304 -8.654 -14.740 1.00 49.11 O ANISOU 932 O3' DA B 2 4561 9266 4831 934 96 -1775 O ATOM 933 C2' DA B 2 -17.984 -6.910 -16.473 1.00 50.52 C ANISOU 933 C2' DA B 2 4826 9556 4815 831 218 -1708 C ATOM 934 C1' DA B 2 -18.636 -6.728 -17.842 1.00 51.11 C ANISOU 934 C1' DA B 2 4928 9716 4775 864 223 -1693 C ATOM 935 N9 DA B 2 -19.429 -5.507 -17.940 1.00 43.93 N ANISOU 935 N9 DA B 2 4157 8781 3752 904 289 -1556 N ATOM 936 C8 DA B 2 -20.748 -5.350 -17.619 1.00 40.45 C ANISOU 936 C8 DA B 2 3731 8342 3296 1010 243 -1487 C ATOM 937 N7 DA B 2 -21.195 -4.129 -17.803 1.00 36.73 N ANISOU 937 N7 DA B 2 3414 7845 2699 1056 319 -1360 N ATOM 938 C5 DA B 2 -20.090 -3.437 -18.271 1.00 40.13 C ANISOU 938 C5 DA B 2 3960 8231 3058 951 445 -1344 C ATOM 939 C6 DA B 2 -19.901 -2.094 -18.655 1.00 39.44 C ANISOU 939 C6 DA B 2 4097 8064 2822 928 601 -1232 C ATOM 940 N6 DA B 2 -20.871 -1.176 -18.622 1.00 43.51 N ANISOU 940 N6 DA B 2 4770 8537 3225 1047 635 -1095 N ATOM 941 N1 DA B 2 -18.671 -1.731 -19.076 1.00 39.43 N ANISOU 941 N1 DA B 2 4169 8022 2789 781 734 -1275 N ATOM 942 C2 DA B 2 -17.701 -2.653 -19.106 1.00 39.14 C ANISOU 942 C2 DA B 2 3961 8046 2863 687 684 -1418 C ATOM 943 N3 DA B 2 -17.759 -3.941 -18.772 1.00 40.83 N ANISOU 943 N3 DA B 2 3966 8336 3211 724 527 -1519 N ATOM 944 C4 DA B 2 -18.992 -4.272 -18.358 1.00 43.06 C ANISOU 944 C4 DA B 2 4208 8631 3521 850 424 -1473 C ATOM 945 P DG B 3 -16.750 -9.081 -14.812 1.00 39.67 P ANISOU 945 P DG B 3 3302 8118 3653 901 81 -1881 P ATOM 946 OP1 DG B 3 -16.420 -9.549 -16.177 1.00 40.06 O ANISOU 946 OP1 DG B 3 3293 8263 3666 874 68 -1972 O ATOM 947 OP2 DG B 3 -16.522 -9.990 -13.668 1.00 47.19 O ANISOU 947 OP2 DG B 3 4246 8996 4687 989 28 -1911 O ATOM 948 O5' DG B 3 -15.936 -7.731 -14.530 1.00 35.11 O ANISOU 948 O5' DG B 3 2758 7557 3024 799 166 -1840 O ATOM 949 C5' DG B 3 -14.723 -7.481 -15.235 1.00 36.14 C ANISOU 949 C5' DG B 3 2838 7775 3118 704 207 -1930 C ATOM 950 C4' DG B 3 -14.365 -6.004 -15.212 1.00 45.06 C ANISOU 950 C4' DG B 3 4053 8883 4185 575 343 -1877 C ATOM 951 O4' DG B 3 -15.471 -5.212 -15.698 1.00 42.81 O ANISOU 951 O4' DG B 3 3906 8538 3820 586 415 -1744 O ATOM 952 C3' DG B 3 -14.020 -5.439 -13.831 1.00 51.77 C ANISOU 952 C3' DG B 3 4907 9688 5076 547 362 -1865 C ATOM 953 O3' DG B 3 -12.649 -5.082 -13.789 1.00 52.90 O ANISOU 953 O3' DG B 3 4974 9909 5218 428 409 -1989 O ATOM 954 C2' DG B 3 -14.930 -4.206 -13.677 1.00 35.77 C ANISOU 954 C2' DG B 3 3042 7555 2995 514 475 -1718 C ATOM 955 C1' DG B 3 -15.388 -3.946 -15.104 1.00 36.40 C ANISOU 955 C1' DG B 3 3208 7646 2976 507 536 -1672 C ATOM 956 N9 DG B 3 -16.692 -3.289 -15.192 1.00 56.75 N ANISOU 956 N9 DG B 3 5927 10152 5484 580 573 -1524 N ATOM 957 C8 DG B 3 -17.921 -3.841 -14.916 1.00 59.63 C ANISOU 957 C8 DG B 3 6264 10514 5877 715 468 -1466 C ATOM 958 N7 DG B 3 -18.914 -3.010 -15.080 1.00 58.40 N ANISOU 958 N7 DG B 3 6237 10318 5634 773 519 -1345 N ATOM 959 C5 DG B 3 -18.306 -1.829 -15.490 1.00 56.16 C ANISOU 959 C5 DG B 3 6112 9978 5250 674 682 -1304 C ATOM 960 C6 DG B 3 -18.876 -0.575 -15.819 1.00 41.17 C ANISOU 960 C6 DG B 3 4433 7996 3211 703 812 -1172 C ATOM 961 O6 DG B 3 -20.072 -0.248 -15.813 1.00 37.03 O ANISOU 961 O6 DG B 3 3982 7462 2623 843 780 -1063 O ATOM 962 N1 DG B 3 -17.904 0.353 -16.185 1.00 41.05 N ANISOU 962 N1 DG B 3 4571 7904 3121 557 1004 -1181 N ATOM 963 C2 DG B 3 -16.553 0.101 -16.227 1.00 38.84 C ANISOU 963 C2 DG B 3 4198 7653 2906 399 1048 -1317 C ATOM 964 N2 DG B 3 -15.771 1.123 -16.604 1.00 40.41 N ANISOU 964 N2 DG B 3 4567 7763 3022 257 1262 -1322 N ATOM 965 N3 DG B 3 -16.005 -1.069 -15.921 1.00 38.06 N ANISOU 965 N3 DG B 3 3864 7662 2936 391 898 -1445 N ATOM 966 C4 DG B 3 -16.938 -1.984 -15.563 1.00 62.21 C ANISOU 966 C4 DG B 3 6812 10767 6058 537 727 -1421 C ATOM 967 P DC B 4 -11.960 -4.678 -12.397 1.00 57.93 P ANISOU 967 P DC B 4 5552 10566 5892 395 398 -2046 P ATOM 968 OP1 DC B 4 -10.507 -4.909 -12.551 1.00 69.52 O ANISOU 968 OP1 DC B 4 6864 12185 7366 323 375 -2234 O ATOM 969 OP2 DC B 4 -12.703 -5.355 -11.310 1.00 52.23 O ANISOU 969 OP2 DC B 4 4837 9792 5216 559 284 -1976 O ATOM 970 O5' DC B 4 -12.226 -3.102 -12.281 1.00 73.55 O ANISOU 970 O5' DC B 4 7682 12439 7826 249 581 -1962 O ATOM 971 C5' DC B 4 -11.678 -2.220 -13.255 1.00 71.78 C ANISOU 971 C5' DC B 4 7533 12202 7537 81 749 -1996 C ATOM 972 C4' DC B 4 -12.189 -0.801 -13.064 1.00 65.17 C ANISOU 972 C4' DC B 4 6904 11213 6645 -10 932 -1880 C ATOM 973 O4' DC B 4 -13.526 -0.686 -13.585 1.00 61.53 O ANISOU 973 O4' DC B 4 6605 10654 6118 107 946 -1704 O ATOM 974 C3' DC B 4 -12.321 -0.344 -11.626 1.00 61.37 C ANISOU 974 C3' DC B 4 6416 10687 6213 -13 922 -1867 C ATOM 975 O3' DC B 4 -11.069 0.131 -11.141 1.00 76.10 O ANISOU 975 O3' DC B 4 8179 12630 8107 -177 978 -2036 O ATOM 976 C2' DC B 4 -13.341 0.793 -11.735 1.00 56.49 C ANISOU 976 C2' DC B 4 6049 9891 5523 -20 1079 -1693 C ATOM 977 C1' DC B 4 -14.133 0.452 -13.004 1.00 60.56 C ANISOU 977 C1' DC B 4 6660 10392 5959 83 1071 -1590 C ATOM 978 N1 DC B 4 -15.573 0.161 -12.744 1.00 59.22 N ANISOU 978 N1 DC B 4 6538 10179 5784 261 975 -1445 N ATOM 979 C2 DC B 4 -16.512 1.198 -12.820 1.00 48.11 C ANISOU 979 C2 DC B 4 5349 8647 4284 298 1095 -1295 C ATOM 980 O2 DC B 4 -16.129 2.339 -13.109 1.00 39.81 O ANISOU 980 O2 DC B 4 4483 7494 3150 187 1298 -1271 O ATOM 981 N3 DC B 4 -17.818 0.921 -12.579 1.00 35.99 N ANISOU 981 N3 DC B 4 3823 7105 2746 464 992 -1185 N ATOM 982 C4 DC B 4 -18.190 -0.322 -12.271 1.00 34.82 C ANISOU 982 C4 DC B 4 3494 7045 2691 567 804 -1221 C ATOM 983 N4 DC B 4 -19.488 -0.547 -12.042 1.00 34.04 N ANISOU 983 N4 DC B 4 3400 6940 2594 712 722 -1130 N ATOM 984 C5 DC B 4 -17.248 -1.391 -12.185 1.00 35.86 C ANISOU 984 C5 DC B 4 3443 7271 2910 533 702 -1361 C ATOM 985 C6 DC B 4 -15.964 -1.106 -12.424 1.00 46.02 C ANISOU 985 C6 DC B 4 4705 8589 4192 392 780 -1467 C ATOM 986 P DA B 5 -10.912 0.567 -9.601 1.00 91.30 P ANISOU 986 P DA B 5 10048 14562 10080 -199 953 -2081 P ATOM 987 OP1 DA B 5 -9.467 0.599 -9.287 1.00 93.50 O ANISOU 987 OP1 DA B 5 10129 15013 10385 -335 938 -2318 O ATOM 988 OP2 DA B 5 -11.817 -0.290 -8.804 1.00 89.26 O ANISOU 988 OP2 DA B 5 9763 14295 9857 15 782 -1977 O ATOM 989 O5' DA B 5 -11.486 2.065 -9.555 1.00 85.27 O ANISOU 989 O5' DA B 5 9532 13597 9268 -316 1180 -1964 O ATOM 990 C5' DA B 5 -10.922 3.072 -10.394 1.00 63.40 C ANISOU 990 C5' DA B 5 6892 10756 6443 -512 1402 -2006 C ATOM 991 C4' DA B 5 -11.856 4.268 -10.517 1.00 57.68 C ANISOU 991 C4' DA B 5 6469 9805 5643 -519 1598 -1822 C ATOM 992 O4' DA B 5 -13.189 3.818 -10.877 1.00 57.24 O ANISOU 992 O4' DA B 5 6520 9689 5539 -302 1519 -1626 O ATOM 993 C3' DA B 5 -12.021 5.102 -9.244 1.00 62.67 C ANISOU 993 C3' DA B 5 7143 10357 6312 -577 1656 -1821 C ATOM 994 O3' DA B 5 -11.980 6.487 -9.563 1.00 70.97 O ANISOU 994 O3' DA B 5 8436 11232 7299 -724 1917 -1779 O ATOM 995 C2' DA B 5 -13.397 4.688 -8.729 1.00 49.95 C ANISOU 995 C2' DA B 5 5588 8690 4703 -352 1536 -1638 C ATOM 996 C1' DA B 5 -14.132 4.435 -10.032 1.00 56.21 C ANISOU 996 C1' DA B 5 6518 9435 5403 -234 1555 -1498 C ATOM 997 N9 DA B 5 -15.286 3.551 -9.892 1.00 54.27 N ANISOU 997 N9 DA B 5 6229 9220 5173 -21 1376 -1384 N ATOM 998 C8 DA B 5 -15.282 2.246 -9.487 1.00 44.83 C ANISOU 998 C8 DA B 5 4811 8159 4063 82 1153 -1441 C ATOM 999 N7 DA B 5 -16.473 1.696 -9.459 1.00 40.57 N ANISOU 999 N7 DA B 5 4282 7608 3524 254 1044 -1323 N ATOM 1000 C5 DA B 5 -17.319 2.713 -9.870 1.00 51.65 C ANISOU 1000 C5 DA B 5 5910 8885 4828 277 1186 -1184 C ATOM 1001 C6 DA B 5 -18.715 2.772 -10.051 1.00 35.21 C ANISOU 1001 C6 DA B 5 3920 6764 2693 441 1148 -1036 C ATOM 1002 N6 DA B 5 -19.531 1.737 -9.827 1.00 33.96 N ANISOU 1002 N6 DA B 5 3625 6682 2594 588 964 -1012 N ATOM 1003 N1 DA B 5 -19.241 3.941 -10.473 1.00 36.22 N ANISOU 1003 N1 DA B 5 4293 6773 2695 456 1315 -921 N ATOM 1004 C2 DA B 5 -18.421 4.975 -10.697 1.00 37.75 C ANISOU 1004 C2 DA B 5 4657 6860 2826 302 1535 -946 C ATOM 1005 N3 DA B 5 -17.098 5.040 -10.562 1.00 38.49 N ANISOU 1005 N3 DA B 5 4673 6975 2978 121 1598 -1088 N ATOM 1006 C4 DA B 5 -16.604 3.864 -10.142 1.00 51.88 C ANISOU 1006 C4 DA B 5 6096 8820 4794 120 1401 -1208 C ATOM 1007 P DG B 6 -11.611 7.568 -8.432 1.00 67.08 P ANISOU 1007 P DG B 6 7965 10668 6855 -902 2037 -1873 P ATOM 1008 OP1 DG B 6 -10.447 8.344 -8.915 1.00 67.83 O ANISOU 1008 OP1 DG B 6 8078 10747 6948 -1183 2233 -2049 O ATOM 1009 OP2 DG B 6 -11.535 6.860 -7.135 1.00 64.26 O ANISOU 1009 OP2 DG B 6 7367 10462 6587 -832 1825 -1960 O ATOM 1010 O5' DG B 6 -12.891 8.523 -8.379 1.00 65.00 O ANISOU 1010 O5' DG B 6 8015 10168 6512 -794 2177 -1633 O ATOM 1011 C5' DG B 6 -13.231 9.320 -9.504 1.00 56.90 C ANISOU 1011 C5' DG B 6 7278 8977 5363 -792 2378 -1496 C ATOM 1012 C4' DG B 6 -14.573 9.998 -9.297 1.00 50.80 C ANISOU 1012 C4' DG B 6 6752 8041 4509 -617 2437 -1267 C ATOM 1013 O4' DG B 6 -15.634 9.012 -9.387 1.00 48.98 O ANISOU 1013 O4' DG B 6 6467 7895 4248 -346 2245 -1134 O ATOM 1014 C3' DG B 6 -14.746 10.691 -7.944 1.00 63.16 C ANISOU 1014 C3' DG B 6 8322 9523 6151 -688 2472 -1296 C ATOM 1015 O3' DG B 6 -15.379 11.951 -8.122 1.00 87.48 O ANISOU 1015 O3' DG B 6 11714 12375 9149 -688 2671 -1152 O ATOM 1016 C2' DG B 6 -15.632 9.723 -7.163 1.00 55.75 C ANISOU 1016 C2' DG B 6 7237 8691 5256 -466 2242 -1224 C ATOM 1017 C1' DG B 6 -16.484 9.128 -8.270 1.00 54.15 C ANISOU 1017 C1' DG B 6 7119 8511 4944 -245 2181 -1063 C ATOM 1018 N9 DG B 6 -17.006 7.804 -7.950 1.00 57.97 N ANISOU 1018 N9 DG B 6 7403 9129 5492 -93 1941 -1060 N ATOM 1019 C8 DG B 6 -16.277 6.676 -7.666 1.00 57.34 C ANISOU 1019 C8 DG B 6 7045 9220 5523 -135 1757 -1210 C ATOM 1020 N7 DG B 6 -17.014 5.631 -7.416 1.00 54.18 N ANISOU 1020 N7 DG B 6 6516 8904 5165 27 1557 -1164 N ATOM 1021 C5 DG B 6 -18.316 6.095 -7.543 1.00 51.50 C ANISOU 1021 C5 DG B 6 6360 8458 4749 167 1605 -991 C ATOM 1022 C6 DG B 6 -19.543 5.413 -7.389 1.00 35.37 C ANISOU 1022 C6 DG B 6 4257 6460 2720 358 1443 -892 C ATOM 1023 O6 DG B 6 -19.727 4.224 -7.097 1.00 34.08 O ANISOU 1023 O6 DG B 6 3891 6416 2643 442 1241 -925 O ATOM 1024 N1 DG B 6 -20.633 6.253 -7.607 1.00 35.80 N ANISOU 1024 N1 DG B 6 4521 6408 2672 467 1536 -742 N ATOM 1025 C2 DG B 6 -20.544 7.586 -7.935 1.00 57.17 C ANISOU 1025 C2 DG B 6 7509 8955 5260 400 1785 -685 C ATOM 1026 N2 DG B 6 -21.705 8.236 -8.106 1.00 50.16 N ANISOU 1026 N2 DG B 6 6790 7991 4277 550 1810 -533 N ATOM 1027 N3 DG B 6 -19.397 8.238 -8.082 1.00 54.41 N ANISOU 1027 N3 DG B 6 7239 8543 4889 241 1959 -755 N ATOM 1028 C4 DG B 6 -18.328 7.432 -7.872 1.00 54.72 C ANISOU 1028 C4 DG B 6 7033 8708 5050 112 1845 -920 C ATOM 1029 P DG B 7 -15.635 12.916 -6.862 1.00 87.88 P ANISOU 1029 P DG B 7 11844 12278 9267 -777 2759 -1167 P ATOM 1030 OP1 DG B 7 -15.493 14.310 -7.339 1.00 93.28 O ANISOU 1030 OP1 DG B 7 12851 12689 9902 -935 3041 -1133 O ATOM 1031 OP2 DG B 7 -14.799 12.435 -5.739 1.00 85.34 O ANISOU 1031 OP2 DG B 7 11227 12118 9080 -916 2645 -1387 O ATOM 1032 O5' DG B 7 -17.166 12.653 -6.480 1.00 72.73 O ANISOU 1032 O5' DG B 7 9979 10356 7299 -479 2629 -956 O ATOM 1033 C5' DG B 7 -18.202 13.047 -7.374 1.00 62.60 C ANISOU 1033 C5' DG B 7 8950 8958 5877 -295 2681 -744 C ATOM 1034 C4' DG B 7 -19.564 12.913 -6.715 1.00 66.55 C ANISOU 1034 C4' DG B 7 9463 9456 6367 -71 2562 -606 C ATOM 1035 O4' DG B 7 -19.930 11.509 -6.633 1.00 64.66 O ANISOU 1035 O4' DG B 7 8964 9464 6138 87 2330 -623 O ATOM 1036 C3' DG B 7 -19.647 13.456 -5.288 1.00 68.07 C ANISOU 1036 C3' DG B 7 9634 9563 6667 -153 2593 -656 C ATOM 1037 O3' DG B 7 -20.887 14.127 -5.090 1.00 67.49 O ANISOU 1037 O3' DG B 7 9779 9313 6551 13 2627 -481 O ATOM 1038 C2' DG B 7 -19.552 12.196 -4.436 1.00 61.04 C ANISOU 1038 C2' DG B 7 8416 8913 5865 -96 2373 -753 C ATOM 1039 C1' DG B 7 -20.287 11.193 -5.307 1.00 56.54 C ANISOU 1039 C1' DG B 7 7790 8482 5210 123 2230 -655 C ATOM 1040 N9 DG B 7 -19.907 9.812 -5.039 1.00 45.93 N ANISOU 1040 N9 DG B 7 6195 7303 3955 157 2053 -749 N ATOM 1041 C8 DG B 7 -18.633 9.321 -4.889 1.00 40.94 C ANISOU 1041 C8 DG B 7 5378 6758 3419 -17 2003 -927 C ATOM 1042 N7 DG B 7 -18.595 8.041 -4.651 1.00 38.80 N ANISOU 1042 N7 DG B 7 4883 6633 3228 42 1793 -985 N ATOM 1043 C5 DG B 7 -19.929 7.656 -4.640 1.00 41.46 C ANISOU 1043 C5 DG B 7 5249 6961 3542 235 1705 -847 C ATOM 1044 C6 DG B 7 -20.509 6.383 -4.431 1.00 34.13 C ANISOU 1044 C6 DG B 7 4126 6160 2683 373 1470 -833 C ATOM 1045 O6 DG B 7 -19.937 5.306 -4.208 1.00 33.42 O ANISOU 1045 O6 DG B 7 3829 6197 2671 367 1312 -929 O ATOM 1046 N1 DG B 7 -21.899 6.432 -4.505 1.00 33.59 N ANISOU 1046 N1 DG B 7 4125 6060 2579 553 1425 -687 N ATOM 1047 C2 DG B 7 -22.634 7.570 -4.748 1.00 35.73 C ANISOU 1047 C2 DG B 7 4627 6201 2749 613 1571 -566 C ATOM 1048 N2 DG B 7 -23.967 7.421 -4.781 1.00 51.07 N ANISOU 1048 N2 DG B 7 6577 8146 4680 830 1465 -434 N ATOM 1049 N3 DG B 7 -22.102 8.769 -4.945 1.00 36.12 N ANISOU 1049 N3 DG B 7 4893 6116 2715 476 1811 -580 N ATOM 1050 C4 DG B 7 -20.750 8.737 -4.876 1.00 41.46 C ANISOU 1050 C4 DG B 7 5510 6812 3433 302 1875 -712 C ATOM 1051 P DG B 8 -21.143 14.970 -3.746 1.00 74.46 P ANISOU 1051 P DG B 8 10726 10043 7522 -54 2706 -499 P ATOM 1052 OP1 DG B 8 -22.355 15.794 -3.953 1.00 73.90 O ANISOU 1052 OP1 DG B 8 10958 9737 7383 150 2777 -292 O ATOM 1053 OP2 DG B 8 -19.866 15.622 -3.378 1.00 79.26 O ANISOU 1053 OP2 DG B 8 11329 10581 8204 -358 2866 -683 O ATOM 1054 O5' DG B 8 -21.445 13.850 -2.643 1.00 70.09 O ANISOU 1054 O5' DG B 8 9853 9728 7050 25 2482 -564 O ATOM 1055 C5' DG B 8 -22.643 13.897 -1.884 1.00 67.10 C ANISOU 1055 C5' DG B 8 9503 9301 6691 195 2414 -458 C ATOM 1056 C4' DG B 8 -23.499 12.669 -2.147 1.00 58.23 C ANISOU 1056 C4' DG B 8 8227 8346 5551 415 2209 -387 C ATOM 1057 O4' DG B 8 -22.659 11.564 -2.515 1.00 48.96 O ANISOU 1057 O4' DG B 8 6823 7397 4382 345 2110 -514 O ATOM 1058 C3' DG B 8 -24.281 12.173 -0.946 1.00 47.31 C ANISOU 1058 C3' DG B 8 6704 7020 4252 518 2085 -376 C ATOM 1059 O3' DG B 8 -25.539 12.823 -0.895 1.00 37.44 O ANISOU 1059 O3' DG B 8 5634 5613 2981 720 2100 -206 O ATOM 1060 C2' DG B 8 -24.437 10.669 -1.212 1.00 36.10 C ANISOU 1060 C2' DG B 8 5049 5806 2859 627 1880 -395 C ATOM 1061 C1' DG B 8 -23.338 10.358 -2.237 1.00 37.68 C ANISOU 1061 C1' DG B 8 5217 6095 3005 495 1920 -495 C ATOM 1062 N9 DG B 8 -22.361 9.375 -1.777 1.00 43.96 N ANISOU 1062 N9 DG B 8 5792 7023 3889 394 1827 -644 N ATOM 1063 C8 DG B 8 -21.012 9.573 -1.607 1.00 47.72 C ANISOU 1063 C8 DG B 8 6210 7522 4399 218 1875 -777 C ATOM 1064 N7 DG B 8 -20.379 8.513 -1.192 1.00 44.63 N ANISOU 1064 N7 DG B 8 5585 7276 4098 182 1701 -891 N ATOM 1065 C5 DG B 8 -21.370 7.546 -1.079 1.00 45.84 C ANISOU 1065 C5 DG B 8 5643 7494 4281 356 1529 -807 C ATOM 1066 C6 DG B 8 -21.281 6.194 -0.670 1.00 43.06 C ANISOU 1066 C6 DG B 8 5076 7279 4004 430 1314 -850 C ATOM 1067 O6 DG B 8 -20.275 5.565 -0.316 1.00 49.89 O ANISOU 1067 O6 DG B 8 5792 8252 4910 370 1225 -975 O ATOM 1068 N1 DG B 8 -22.523 5.564 -0.698 1.00 31.04 N ANISOU 1068 N1 DG B 8 3529 5766 2500 606 1205 -732 N ATOM 1069 C2 DG B 8 -23.701 6.164 -1.072 1.00 39.39 C ANISOU 1069 C2 DG B 8 4716 6742 3508 717 1260 -598 C ATOM 1070 N2 DG B 8 -24.798 5.393 -1.034 1.00 44.67 N ANISOU 1070 N2 DG B 8 5307 7449 4216 878 1131 -523 N ATOM 1071 N3 DG B 8 -23.800 7.431 -1.458 1.00 55.56 N ANISOU 1071 N3 DG B 8 6967 8674 5470 684 1439 -547 N ATOM 1072 C4 DG B 8 -22.598 8.060 -1.436 1.00 50.01 C ANISOU 1072 C4 DG B 8 6323 7933 4746 487 1585 -658 C ATOM 1073 P DG B 9 -26.217 13.151 0.522 1.00 60.96 P ANISOU 1073 P DG B 9 8591 8530 6040 754 2093 -194 P ATOM 1074 OP1 DG B 9 -27.297 14.134 0.285 1.00 80.27 O ANISOU 1074 OP1 DG B 9 11283 10783 8430 953 2166 -29 O ATOM 1075 OP2 DG B 9 -25.136 13.459 1.484 1.00 64.03 O ANISOU 1075 OP2 DG B 9 8908 8936 6487 494 2176 -362 O ATOM 1076 O5' DG B 9 -26.868 11.762 0.961 1.00 46.75 O ANISOU 1076 O5' DG B 9 6527 6929 4307 895 1869 -191 O ATOM 1077 C5' DG B 9 -27.789 11.111 0.102 1.00 34.49 C ANISOU 1077 C5' DG B 9 4923 5462 2721 1123 1728 -91 C ATOM 1078 C4' DG B 9 -28.134 9.735 0.632 1.00 37.99 C ANISOU 1078 C4' DG B 9 5090 6085 3258 1168 1534 -138 C ATOM 1079 O4' DG B 9 -26.966 8.874 0.552 1.00 47.18 O ANISOU 1079 O4' DG B 9 6107 7366 4453 1011 1481 -262 O ATOM 1080 C3' DG B 9 -28.589 9.702 2.092 1.00 32.06 C ANISOU 1080 C3' DG B 9 4268 5313 2599 1153 1517 -154 C ATOM 1081 O3' DG B 9 -29.686 8.812 2.224 1.00 40.75 O ANISOU 1081 O3' DG B 9 5215 6507 3761 1297 1368 -121 O ATOM 1082 C2' DG B 9 -27.352 9.189 2.828 1.00 31.37 C ANISOU 1082 C2' DG B 9 4064 5296 2560 953 1507 -291 C ATOM 1083 C1' DG B 9 -26.757 8.249 1.797 1.00 37.47 C ANISOU 1083 C1' DG B 9 4728 6192 3316 942 1411 -336 C ATOM 1084 N9 DG B 9 -25.326 8.027 1.972 1.00 44.26 N ANISOU 1084 N9 DG B 9 5519 7114 4182 759 1429 -479 N ATOM 1085 C8 DG B 9 -24.335 8.978 1.968 1.00 46.56 C ANISOU 1085 C8 DG B 9 5915 7349 4427 584 1598 -569 C ATOM 1086 N7 DG B 9 -23.141 8.485 2.151 1.00 37.62 N ANISOU 1086 N7 DG B 9 4661 6307 3326 459 1552 -705 N ATOM 1087 C5 DG B 9 -23.355 7.119 2.284 1.00 40.51 C ANISOU 1087 C5 DG B 9 4853 6791 3749 567 1347 -696 C ATOM 1088 C6 DG B 9 -22.432 6.070 2.500 1.00 33.89 C ANISOU 1088 C6 DG B 9 3847 6083 2946 543 1211 -801 C ATOM 1089 O6 DG B 9 -21.201 6.145 2.621 1.00 31.40 O ANISOU 1089 O6 DG B 9 3470 5835 2627 423 1218 -936 O ATOM 1090 N1 DG B 9 -23.067 4.832 2.574 1.00 32.37 N ANISOU 1090 N1 DG B 9 3559 5947 2794 688 1057 -744 N ATOM 1091 C2 DG B 9 -24.422 4.635 2.454 1.00 33.62 C ANISOU 1091 C2 DG B 9 3749 6053 2972 816 1034 -620 C ATOM 1092 N2 DG B 9 -24.850 3.368 2.553 1.00 37.97 N ANISOU 1092 N2 DG B 9 4204 6652 3570 916 912 -603 N ATOM 1093 N3 DG B 9 -25.298 5.610 2.250 1.00 35.76 N ANISOU 1093 N3 DG B 9 4141 6230 3214 851 1133 -528 N ATOM 1094 C4 DG B 9 -24.695 6.821 2.176 1.00 41.35 C ANISOU 1094 C4 DG B 9 4973 6871 3868 733 1286 -563 C ATOM 1095 P DG B 10 -30.514 8.716 3.598 1.00 47.45 P ANISOU 1095 P DG B 10 5999 7332 4699 1321 1349 -115 P ATOM 1096 OP1 DG B 10 -31.893 9.158 3.298 1.00 72.88 O ANISOU 1096 OP1 DG B 10 9254 10535 7904 1517 1336 -34 O ATOM 1097 OP2 DG B 10 -29.762 9.380 4.687 1.00 33.95 O ANISOU 1097 OP2 DG B 10 4368 5536 2997 1172 1460 -163 O ATOM 1098 O5' DG B 10 -30.542 7.146 3.896 1.00 39.09 O ANISOU 1098 O5' DG B 10 4727 6397 3728 1293 1203 -176 O ATOM 1099 C5' DG B 10 -29.491 6.320 3.413 1.00 30.01 C ANISOU 1099 C5' DG B 10 3502 5330 2572 1210 1145 -244 C ATOM 1100 C4' DG B 10 -29.658 4.897 3.900 1.00 31.81 C ANISOU 1100 C4' DG B 10 3581 5625 2881 1207 1039 -287 C ATOM 1101 O4' DG B 10 -28.353 4.309 4.097 1.00 37.40 O ANISOU 1101 O4' DG B 10 4250 6380 3578 1115 1007 -364 O ATOM 1102 C3' DG B 10 -30.341 4.765 5.244 1.00 41.14 C ANISOU 1102 C3' DG B 10 4754 6755 4123 1213 1059 -269 C ATOM 1103 O3' DG B 10 -30.885 3.460 5.387 1.00 40.19 O ANISOU 1103 O3' DG B 10 4528 6666 4074 1233 992 -290 O ATOM 1104 C2' DG B 10 -29.186 5.001 6.213 1.00 51.75 C ANISOU 1104 C2' DG B 10 6142 8084 5436 1112 1094 -317 C ATOM 1105 C1' DG B 10 -27.994 4.394 5.466 1.00 41.42 C ANISOU 1105 C1' DG B 10 4780 6859 4099 1064 1032 -387 C ATOM 1106 N9 DG B 10 -26.778 5.195 5.573 1.00 36.42 N ANISOU 1106 N9 DG B 10 4193 6233 3410 950 1089 -460 N ATOM 1107 C8 DG B 10 -26.678 6.562 5.477 1.00 32.29 C ANISOU 1107 C8 DG B 10 3787 5636 2847 884 1219 -457 C ATOM 1108 N7 DG B 10 -25.460 7.005 5.614 1.00 29.61 N ANISOU 1108 N7 DG B 10 3455 5322 2473 748 1271 -566 N ATOM 1109 C5 DG B 10 -24.701 5.859 5.813 1.00 35.92 C ANISOU 1109 C5 DG B 10 4123 6237 3286 753 1141 -639 C ATOM 1110 C6 DG B 10 -23.309 5.712 6.023 1.00 34.66 C ANISOU 1110 C6 DG B 10 3889 6177 3104 659 1109 -778 C ATOM 1111 O6 DG B 10 -22.442 6.597 6.075 1.00 30.76 O ANISOU 1111 O6 DG B 10 3420 5684 2585 518 1201 -881 O ATOM 1112 N1 DG B 10 -22.950 4.376 6.182 1.00 30.00 N ANISOU 1112 N1 DG B 10 3186 5692 2519 750 960 -805 N ATOM 1113 C2 DG B 10 -23.825 3.316 6.143 1.00 36.06 C ANISOU 1113 C2 DG B 10 3940 6443 3319 887 884 -711 C ATOM 1114 N2 DG B 10 -23.292 2.099 6.318 1.00 33.65 N ANISOU 1114 N2 DG B 10 3562 6223 3002 971 772 -752 N ATOM 1115 N3 DG B 10 -25.133 3.439 5.948 1.00 41.55 N ANISOU 1115 N3 DG B 10 4690 7045 4051 942 923 -597 N ATOM 1116 C4 DG B 10 -25.499 4.735 5.792 1.00 38.14 C ANISOU 1116 C4 DG B 10 4348 6536 3608 882 1038 -566 C ATOM 1117 P DC B 11 -31.691 3.057 6.718 1.00 39.06 P ANISOU 1117 P DC B 11 4383 6464 3995 1230 1030 -276 P ATOM 1118 OP1 DC B 11 -32.596 1.942 6.359 1.00 37.75 O ANISOU 1118 OP1 DC B 11 4116 6320 3906 1245 999 -309 O ATOM 1119 OP2 DC B 11 -32.240 4.296 7.315 1.00 42.67 O ANISOU 1119 OP2 DC B 11 4911 6865 4437 1250 1108 -233 O ATOM 1120 O5' DC B 11 -30.557 2.506 7.701 1.00 33.01 O ANISOU 1120 O5' DC B 11 3658 5689 3194 1184 1023 -301 O ATOM 1121 C5' DC B 11 -29.704 1.454 7.273 1.00 36.61 C ANISOU 1121 C5' DC B 11 4077 6195 3638 1186 953 -346 C ATOM 1122 C4' DC B 11 -28.623 1.175 8.301 1.00 31.25 C ANISOU 1122 C4' DC B 11 3443 5539 2890 1193 940 -375 C ATOM 1123 O4' DC B 11 -27.522 2.103 8.128 1.00 27.68 O ANISOU 1123 O4' DC B 11 2989 5153 2374 1136 931 -431 O ATOM 1124 C3' DC B 11 -29.061 1.305 9.766 1.00 30.36 C ANISOU 1124 C3' DC B 11 3408 5364 2765 1207 999 -336 C ATOM 1125 O3' DC B 11 -28.636 0.161 10.491 1.00 36.30 O ANISOU 1125 O3' DC B 11 4209 6105 3477 1275 973 -337 O ATOM 1126 C2' DC B 11 -28.332 2.565 10.239 1.00 32.55 C ANISOU 1126 C2' DC B 11 3709 5680 2977 1154 1021 -374 C ATOM 1127 C1' DC B 11 -27.073 2.493 9.399 1.00 32.81 C ANISOU 1127 C1' DC B 11 3685 5809 2973 1123 950 -454 C ATOM 1128 N1 DC B 11 -26.344 3.785 9.280 1.00 31.84 N ANISOU 1128 N1 DC B 11 3572 5708 2819 1012 993 -519 N ATOM 1129 C2 DC B 11 -24.952 3.802 9.415 1.00 32.85 C ANISOU 1129 C2 DC B 11 3648 5943 2889 963 946 -637 C ATOM 1130 O2 DC B 11 -24.355 2.740 9.631 1.00 33.75 O ANISOU 1130 O2 DC B 11 3712 6142 2968 1046 848 -672 O ATOM 1131 N3 DC B 11 -24.294 4.982 9.304 1.00 30.98 N ANISOU 1131 N3 DC B 11 3424 5713 2634 829 1020 -720 N ATOM 1132 C4 DC B 11 -24.974 6.103 9.070 1.00 41.96 C ANISOU 1132 C4 DC B 11 4907 6990 4047 769 1145 -671 C ATOM 1133 N4 DC B 11 -24.283 7.243 8.968 1.00 45.21 N ANISOU 1133 N4 DC B 11 5362 7381 4434 629 1255 -759 N ATOM 1134 C5 DC B 11 -26.395 6.107 8.928 1.00 46.56 C ANISOU 1134 C5 DC B 11 5544 7473 4674 857 1174 -537 C ATOM 1135 C6 DC B 11 -27.032 4.936 9.040 1.00 38.10 C ANISOU 1135 C6 DC B 11 4426 6414 3635 966 1091 -475 C ATOM 1136 P DG B 12 -29.375 -0.267 11.853 1.00 46.75 P ANISOU 1136 P DG B 12 5644 7324 4793 1308 1051 -275 P ATOM 1137 OP1 DG B 12 -30.369 -1.308 11.512 1.00 56.67 O ANISOU 1137 OP1 DG B 12 6915 8473 6146 1293 1102 -247 O ATOM 1138 OP2 DG B 12 -29.814 0.962 12.550 1.00 45.62 O ANISOU 1138 OP2 DG B 12 5515 7175 4642 1262 1112 -261 O ATOM 1139 O5' DG B 12 -28.205 -0.930 12.720 1.00 41.58 O ANISOU 1139 O5' DG B 12 5068 6726 4004 1426 996 -293 O ATOM 1140 C5' DG B 12 -27.373 -1.926 12.140 1.00 44.21 C ANISOU 1140 C5' DG B 12 5390 7101 4305 1508 917 -328 C ATOM 1141 C4' DG B 12 -25.917 -1.687 12.494 1.00 55.96 C ANISOU 1141 C4' DG B 12 6839 8770 5654 1595 821 -417 C ATOM 1142 O4' DG B 12 -25.535 -0.345 12.097 1.00 47.80 O ANISOU 1142 O4' DG B 12 5691 7825 4645 1456 803 -490 O ATOM 1143 C3' DG B 12 -25.582 -1.806 13.983 1.00 62.45 C ANISOU 1143 C3' DG B 12 7769 9624 6336 1720 817 -404 C ATOM 1144 O3' DG B 12 -24.381 -2.549 14.154 1.00 71.63 O ANISOU 1144 O3' DG B 12 8934 10901 7380 1882 699 -461 O ATOM 1145 C2' DG B 12 -25.414 -0.353 14.427 1.00 50.80 C ANISOU 1145 C2' DG B 12 6218 8219 4863 1588 816 -462 C ATOM 1146 C1' DG B 12 -24.872 0.291 13.163 1.00 40.50 C ANISOU 1146 C1' DG B 12 4770 6986 3632 1457 775 -547 C ATOM 1147 N9 DG B 12 -25.134 1.725 13.080 1.00 40.22 N ANISOU 1147 N9 DG B 12 4701 6929 3653 1292 842 -574 N ATOM 1148 C8 DG B 12 -26.362 2.341 13.021 1.00 37.64 C ANISOU 1148 C8 DG B 12 4421 6473 3407 1225 947 -491 C ATOM 1149 N7 DG B 12 -26.288 3.641 12.948 1.00 35.70 N ANISOU 1149 N7 DG B 12 4164 6219 3183 1103 1002 -535 N ATOM 1150 C5 DG B 12 -24.924 3.906 12.958 1.00 41.06 C ANISOU 1150 C5 DG B 12 4774 7027 3801 1056 945 -666 C ATOM 1151 C6 DG B 12 -24.234 5.140 12.901 1.00 48.88 C ANISOU 1151 C6 DG B 12 5738 8049 4785 907 1001 -779 C ATOM 1152 O6 DG B 12 -24.709 6.282 12.827 1.00 46.75 O ANISOU 1152 O6 DG B 12 5530 7679 4555 804 1122 -768 O ATOM 1153 N1 DG B 12 -22.853 4.959 12.936 1.00 31.50 N ANISOU 1153 N1 DG B 12 3433 6010 2524 888 915 -924 N ATOM 1154 C2 DG B 12 -22.221 3.741 13.018 1.00 31.83 C ANISOU 1154 C2 DG B 12 3411 6176 2506 1030 778 -947 C ATOM 1155 N2 DG B 12 -20.881 3.768 13.040 1.00 32.95 N ANISOU 1155 N2 DG B 12 3429 6497 2594 1004 698 -1110 N ATOM 1156 N3 DG B 12 -22.855 2.578 13.072 1.00 31.35 N ANISOU 1156 N3 DG B 12 3409 6065 2439 1190 735 -828 N ATOM 1157 C4 DG B 12 -24.200 2.736 13.038 1.00 39.33 C ANISOU 1157 C4 DG B 12 4514 6912 3519 1178 831 -696 C ATOM 1158 P DC B 13 -23.975 -3.110 15.604 1.00 65.30 P ANISOU 1158 P DC B 13 8282 10127 6403 2094 666 -427 P ATOM 1159 OP1 DC B 13 -23.441 -4.479 15.422 1.00 62.28 O ANISOU 1159 OP1 DC B 13 8000 9727 5938 2312 616 -405 O ATOM 1160 OP2 DC B 13 -25.120 -2.881 16.513 1.00 51.07 O ANISOU 1160 OP2 DC B 13 6622 8176 4608 2055 802 -320 O ATOM 1161 O5' DC B 13 -22.781 -2.150 16.065 1.00 64.86 O ANISOU 1161 O5' DC B 13 8064 10309 6271 2068 535 -574 O ATOM 1162 C5' DC B 13 -21.559 -2.132 15.333 1.00 57.16 C ANISOU 1162 C5' DC B 13 6915 9516 5288 2068 408 -714 C ATOM 1163 C4' DC B 13 -20.596 -1.107 15.909 1.00 55.49 C ANISOU 1163 C4' DC B 13 6545 9517 5022 1996 330 -874 C ATOM 1164 O4' DC B 13 -21.039 0.230 15.557 1.00 54.70 O ANISOU 1164 O4' DC B 13 6381 9361 5042 1725 433 -909 O ATOM 1165 C3' DC B 13 -20.466 -1.128 17.435 1.00 66.85 C ANISOU 1165 C3' DC B 13 8061 11028 6312 2152 292 -866 C ATOM 1166 O3' DC B 13 -19.099 -1.016 17.809 1.00 70.24 O ANISOU 1166 O3' DC B 13 8319 11730 6637 2241 141 -1040 O ATOM 1167 C2' DC B 13 -21.268 0.096 17.875 1.00 64.40 C ANISOU 1167 C2' DC B 13 7765 10628 6074 1938 415 -854 C ATOM 1168 C1' DC B 13 -21.039 1.041 16.707 1.00 57.32 C ANISOU 1168 C1' DC B 13 6718 9744 5317 1686 454 -954 C ATOM 1169 N1 DC B 13 -22.105 2.070 16.561 1.00 42.12 N ANISOU 1169 N1 DC B 13 4847 7647 3508 1486 606 -893 N ATOM 1170 C2 DC B 13 -21.754 3.422 16.471 1.00 43.75 C ANISOU 1170 C2 DC B 13 4968 7893 3764 1276 663 -1016 C ATOM 1171 O2 DC B 13 -20.559 3.739 16.511 1.00 45.30 O ANISOU 1171 O2 DC B 13 5024 8272 3916 1232 592 -1189 O ATOM 1172 N3 DC B 13 -22.737 4.347 16.340 1.00 50.72 N ANISOU 1172 N3 DC B 13 5926 8607 4740 1133 806 -951 N ATOM 1173 C4 DC B 13 -24.014 3.964 16.302 1.00 46.53 C ANISOU 1173 C4 DC B 13 5510 7909 4259 1187 872 -785 C ATOM 1174 N4 DC B 13 -24.948 4.913 16.173 1.00 38.20 N ANISOU 1174 N4 DC B 13 4511 6714 3291 1069 999 -733 N ATOM 1175 C5 DC B 13 -24.390 2.591 16.395 1.00 41.30 C ANISOU 1175 C5 DC B 13 4919 7214 3562 1366 824 -673 C ATOM 1176 C6 DC B 13 -23.413 1.688 16.522 1.00 36.63 C ANISOU 1176 C6 DC B 13 4292 6757 2870 1513 700 -725 C TER 1177 DC B 13 ATOM 1178 O5' DC C 3 -16.917 11.602 12.922 1.00 87.25 O ANISOU 1178 O5' DC C 3 9586 13567 9998 -761 -400 -1231 O ATOM 1179 C5' DC C 3 -16.164 11.184 14.056 1.00 82.47 C ANISOU 1179 C5' DC C 3 8745 13219 9370 -645 -606 -1479 C ATOM 1180 C4' DC C 3 -16.104 9.671 14.137 1.00 73.78 C ANISOU 1180 C4' DC C 3 7487 12301 8244 -154 -824 -1531 C ATOM 1181 O4' DC C 3 -17.438 9.142 14.356 1.00 59.78 O ANISOU 1181 O4' DC C 3 6070 10108 6537 135 -855 -1283 O ATOM 1182 C3' DC C 3 -15.572 8.985 12.879 1.00 70.87 C ANISOU 1182 C3' DC C 3 6837 12253 7838 -95 -779 -1588 C ATOM 1183 O3' DC C 3 -14.665 7.955 13.230 1.00 64.34 O ANISOU 1183 O3' DC C 3 5696 11835 6914 226 -986 -1837 O ATOM 1184 C2' DC C 3 -16.829 8.426 12.219 1.00 41.97 C ANISOU 1184 C2' DC C 3 3455 8254 4239 124 -732 -1304 C ATOM 1185 C1' DC C 3 -17.700 8.119 13.424 1.00 45.98 C ANISOU 1185 C1' DC C 3 4260 8424 4787 372 -850 -1220 C ATOM 1186 N1 DC C 3 -19.158 8.119 13.116 1.00 43.14 N ANISOU 1186 N1 DC C 3 4221 7653 4516 439 -758 -977 N ATOM 1187 C2 DC C 3 -19.857 6.908 13.078 1.00 39.85 C ANISOU 1187 C2 DC C 3 3903 7122 4115 767 -798 -943 C ATOM 1188 O2 DC C 3 -19.250 5.855 13.306 1.00 36.17 O ANISOU 1188 O2 DC C 3 3330 6846 3566 1025 -902 -1075 O ATOM 1189 N3 DC C 3 -21.184 6.926 12.794 1.00 33.99 N ANISOU 1189 N3 DC C 3 3382 6075 3457 798 -707 -796 N ATOM 1190 C4 DC C 3 -21.800 8.084 12.555 1.00 33.27 C ANISOU 1190 C4 DC C 3 3427 5801 3411 593 -616 -665 C ATOM 1191 N4 DC C 3 -23.108 8.051 12.280 1.00 31.76 N ANISOU 1191 N4 DC C 3 3403 5380 3284 683 -556 -573 N ATOM 1192 C5 DC C 3 -21.104 9.328 12.587 1.00 34.99 C ANISOU 1192 C5 DC C 3 3632 6074 3590 290 -564 -654 C ATOM 1193 C6 DC C 3 -19.798 9.299 12.869 1.00 46.43 C ANISOU 1193 C6 DC C 3 4842 7821 4978 186 -621 -822 C ATOM 1194 P DG C 4 -13.581 7.448 12.159 1.00 76.20 P ANISOU 1194 P DG C 4 6758 13850 8346 217 -957 -2041 P ATOM 1195 OP1 DG C 4 -12.327 7.152 12.885 1.00 90.70 O ANISOU 1195 OP1 DG C 4 8398 15966 10099 366 -1031 -2326 O ATOM 1196 OP2 DG C 4 -13.578 8.416 11.040 1.00 84.29 O ANISOU 1196 OP2 DG C 4 7784 14821 9421 -263 -669 -1958 O ATOM 1197 O5' DG C 4 -14.196 6.079 11.617 1.00 65.45 O ANISOU 1197 O5' DG C 4 5577 12317 6976 664 -994 -1855 O ATOM 1198 C5' DG C 4 -14.438 5.010 12.518 1.00 68.77 C ANISOU 1198 C5' DG C 4 6245 12544 7340 1129 -1128 -1834 C ATOM 1199 C4' DG C 4 -15.146 3.867 11.817 1.00 70.69 C ANISOU 1199 C4' DG C 4 6685 12596 7579 1403 -1078 -1673 C ATOM 1200 O4' DG C 4 -16.545 4.202 11.631 1.00 70.03 O ANISOU 1200 O4' DG C 4 6817 12191 7600 1313 -1037 -1454 O ATOM 1201 C3' DG C 4 -14.601 3.524 10.433 1.00 68.26 C ANISOU 1201 C3' DG C 4 6176 12508 7252 1324 -953 -1691 C ATOM 1202 O3' DG C 4 -14.580 2.120 10.262 1.00 70.53 O ANISOU 1202 O3' DG C 4 6625 12732 7442 1694 -958 -1692 O ATOM 1203 C2' DG C 4 -15.601 4.188 9.489 1.00 60.51 C ANISOU 1203 C2' DG C 4 5211 11402 6379 1068 -850 -1493 C ATOM 1204 C1' DG C 4 -16.896 4.053 10.274 1.00 54.08 C ANISOU 1204 C1' DG C 4 4743 10179 5624 1218 -899 -1342 C ATOM 1205 N9 DG C 4 -17.880 5.077 9.948 1.00 38.07 N ANISOU 1205 N9 DG C 4 2913 7840 3712 932 -761 -1146 N ATOM 1206 C8 DG C 4 -17.637 6.404 9.696 1.00 42.76 C ANISOU 1206 C8 DG C 4 3475 8442 4329 558 -654 -1112 C ATOM 1207 N7 DG C 4 -18.715 7.090 9.438 1.00 50.66 N ANISOU 1207 N7 DG C 4 4746 9112 5391 450 -552 -919 N ATOM 1208 C5 DG C 4 -19.739 6.156 9.525 1.00 44.16 C ANISOU 1208 C5 DG C 4 4072 8095 4613 737 -599 -855 C ATOM 1209 C6 DG C 4 -21.134 6.314 9.342 1.00 40.12 C ANISOU 1209 C6 DG C 4 3798 7277 4169 786 -543 -720 C ATOM 1210 O6 DG C 4 -21.759 7.345 9.058 1.00 33.68 O ANISOU 1210 O6 DG C 4 3141 6290 3365 648 -467 -598 O ATOM 1211 N1 DG C 4 -21.815 5.111 9.522 1.00 37.16 N ANISOU 1211 N1 DG C 4 3484 6810 3825 1038 -568 -768 N ATOM 1212 C2 DG C 4 -21.221 3.910 9.837 1.00 32.72 C ANISOU 1212 C2 DG C 4 2856 6373 3204 1249 -626 -890 C ATOM 1213 N2 DG C 4 -22.041 2.858 9.970 1.00 31.67 N ANISOU 1213 N2 DG C 4 2882 6065 3087 1437 -576 -931 N ATOM 1214 N3 DG C 4 -19.916 3.751 10.012 1.00 34.41 N ANISOU 1214 N3 DG C 4 2875 6872 3326 1284 -713 -993 N ATOM 1215 C4 DG C 4 -19.240 4.912 9.840 1.00 36.97 C ANISOU 1215 C4 DG C 4 3051 7347 3651 1006 -701 -987 C ATOM 1216 P DC C 5 -13.555 1.445 9.227 1.00 73.10 P ANISOU 1216 P DC C 5 6765 13350 7661 1746 -893 -1807 P ATOM 1217 OP1 DC C 5 -12.502 0.771 10.019 1.00 64.72 O ANISOU 1217 OP1 DC C 5 5678 12485 6427 2061 -997 -2034 O ATOM 1218 OP2 DC C 5 -13.183 2.467 8.223 1.00 81.26 O ANISOU 1218 OP2 DC C 5 7512 14596 8767 1334 -781 -1815 O ATOM 1219 O5' DC C 5 -14.444 0.342 8.489 1.00 68.06 O ANISOU 1219 O5' DC C 5 6373 12482 7006 1935 -829 -1651 O ATOM 1220 C5' DC C 5 -15.306 -0.492 9.250 1.00 63.34 C ANISOU 1220 C5' DC C 5 6116 11587 6362 2233 -869 -1596 C ATOM 1221 C4' DC C 5 -16.598 -0.753 8.500 1.00 54.64 C ANISOU 1221 C4' DC C 5 5161 10243 5356 2168 -769 -1428 C ATOM 1222 O4' DC C 5 -17.397 0.449 8.473 1.00 41.70 O ANISOU 1222 O4' DC C 5 3457 8494 3892 1888 -747 -1309 O ATOM 1223 C3' DC C 5 -16.420 -1.176 7.037 1.00 55.43 C ANISOU 1223 C3' DC C 5 5151 10472 5437 2081 -673 -1395 C ATOM 1224 O3' DC C 5 -16.862 -2.517 6.861 1.00 56.95 O ANISOU 1224 O3' DC C 5 5580 10536 5521 2335 -647 -1398 O ATOM 1225 C2' DC C 5 -17.280 -0.183 6.237 1.00 50.97 C ANISOU 1225 C2' DC C 5 4497 9831 5038 1779 -591 -1250 C ATOM 1226 C1' DC C 5 -18.170 0.436 7.306 1.00 40.26 C ANISOU 1226 C1' DC C 5 3263 8252 3780 1766 -639 -1201 C ATOM 1227 N1 DC C 5 -18.591 1.832 6.995 1.00 36.04 N ANISOU 1227 N1 DC C 5 2603 7733 3360 1484 -620 -1101 N ATOM 1228 C2 DC C 5 -19.947 2.118 6.806 1.00 43.02 C ANISOU 1228 C2 DC C 5 3648 8362 4337 1437 -562 -990 C ATOM 1229 O2 DC C 5 -20.775 1.205 6.906 1.00 54.74 O ANISOU 1229 O2 DC C 5 5295 9667 5835 1602 -523 -1016 O ATOM 1230 N3 DC C 5 -20.316 3.391 6.521 1.00 36.44 N ANISOU 1230 N3 DC C 5 2851 7441 3555 1194 -513 -877 N ATOM 1231 C4 DC C 5 -19.393 4.348 6.422 1.00 35.74 C ANISOU 1231 C4 DC C 5 2634 7512 3431 967 -495 -877 C ATOM 1232 N4 DC C 5 -19.806 5.588 6.140 1.00 35.94 N ANISOU 1232 N4 DC C 5 2802 7386 3469 745 -406 -755 N ATOM 1233 C5 DC C 5 -18.005 4.076 6.609 1.00 37.67 C ANISOU 1233 C5 DC C 5 2614 8093 3607 965 -549 -1037 C ATOM 1234 C6 DC C 5 -17.653 2.816 6.890 1.00 42.76 C ANISOU 1234 C6 DC C 5 3220 8829 4196 1256 -630 -1143 C ATOM 1235 P DC C 6 -16.647 -3.264 5.454 1.00 61.76 P ANISOU 1235 P DC C 6 6133 11265 6068 2317 -578 -1380 P ATOM 1236 OP1 DC C 6 -16.479 -4.707 5.737 1.00 71.93 O ANISOU 1236 OP1 DC C 6 7666 12507 7158 2660 -623 -1437 O ATOM 1237 OP2 DC C 6 -15.605 -2.533 4.699 1.00 70.98 O ANISOU 1237 OP2 DC C 6 7001 12719 7250 2112 -564 -1412 O ATOM 1238 O5' DC C 6 -18.033 -3.046 4.693 1.00 50.49 O ANISOU 1238 O5' DC C 6 4750 9638 4797 2132 -477 -1258 O ATOM 1239 C5' DC C 6 -19.243 -3.456 5.306 1.00 46.58 C ANISOU 1239 C5' DC C 6 4481 8854 4362 2216 -437 -1248 C ATOM 1240 C4' DC C 6 -20.440 -2.896 4.563 1.00 47.48 C ANISOU 1240 C4' DC C 6 4545 8865 4631 1996 -349 -1187 C ATOM 1241 O4' DC C 6 -20.468 -1.459 4.696 1.00 36.16 O ANISOU 1241 O4' DC C 6 2964 7480 3293 1818 -383 -1115 O ATOM 1242 C3' DC C 6 -20.462 -3.182 3.058 1.00 46.22 C ANISOU 1242 C3' DC C 6 4288 8825 4449 1899 -305 -1158 C ATOM 1243 O3' DC C 6 -21.562 -4.029 2.749 1.00 46.32 O ANISOU 1243 O3' DC C 6 4432 8659 4510 1904 -220 -1207 O ATOM 1244 C2' DC C 6 -20.601 -1.797 2.401 1.00 33.96 C ANISOU 1244 C2' DC C 6 2574 7362 2968 1693 -302 -1066 C ATOM 1245 C1' DC C 6 -21.074 -0.924 3.553 1.00 33.26 C ANISOU 1245 C1' DC C 6 2517 7144 2977 1663 -334 -1048 C ATOM 1246 N1 DC C 6 -20.667 0.504 3.429 1.00 34.81 N ANISOU 1246 N1 DC C 6 2559 7463 3204 1503 -362 -958 N ATOM 1247 C2 DC C 6 -21.638 1.484 3.187 1.00 41.35 C ANISOU 1247 C2 DC C 6 3391 8228 4094 1433 -355 -884 C ATOM 1248 O2 DC C 6 -22.823 1.145 3.076 1.00 42.76 O ANISOU 1248 O2 DC C 6 3676 8255 4316 1491 -329 -921 O ATOM 1249 N3 DC C 6 -21.251 2.779 3.081 1.00 33.95 N ANISOU 1249 N3 DC C 6 2402 7357 3140 1272 -355 -789 N ATOM 1250 C4 DC C 6 -19.963 3.104 3.208 1.00 35.40 C ANISOU 1250 C4 DC C 6 2440 7730 3280 1147 -351 -813 C ATOM 1251 N4 DC C 6 -19.629 4.394 3.095 1.00 36.60 N ANISOU 1251 N4 DC C 6 2642 7860 3405 901 -281 -737 N ATOM 1252 C5 DC C 6 -18.959 2.120 3.455 1.00 38.67 C ANISOU 1252 C5 DC C 6 2733 8309 3652 1249 -389 -936 C ATOM 1253 C6 DC C 6 -19.353 0.846 3.557 1.00 35.24 C ANISOU 1253 C6 DC C 6 2463 7721 3204 1437 -392 -979 C ATOM 1254 P DC C 7 -21.894 -4.416 1.226 1.00 51.41 P ANISOU 1254 P DC C 7 4999 9394 5141 1817 -184 -1208 P ATOM 1255 OP1 DC C 7 -22.593 -5.720 1.246 1.00 61.66 O ANISOU 1255 OP1 DC C 7 6463 10492 6473 1849 -73 -1301 O ATOM 1256 OP2 DC C 7 -20.655 -4.266 0.430 1.00 61.91 O ANISOU 1256 OP2 DC C 7 6197 10968 6358 1825 -231 -1150 O ATOM 1257 O5' DC C 7 -22.927 -3.286 0.767 1.00 45.09 O ANISOU 1257 O5' DC C 7 4118 8587 4426 1668 -187 -1185 O ATOM 1258 C5' DC C 7 -24.066 -3.000 1.572 1.00 46.11 C ANISOU 1258 C5' DC C 7 4318 8532 4670 1628 -154 -1251 C ATOM 1259 C4' DC C 7 -24.927 -1.927 0.930 1.00 52.39 C ANISOU 1259 C4' DC C 7 5031 9384 5493 1557 -193 -1232 C ATOM 1260 O4' DC C 7 -24.283 -0.635 1.074 1.00 48.91 O ANISOU 1260 O4' DC C 7 4527 9024 5032 1549 -243 -1086 O ATOM 1261 C3' DC C 7 -25.188 -2.118 -0.565 1.00 53.59 C ANISOU 1261 C3' DC C 7 5117 9683 5563 1551 -209 -1252 C ATOM 1262 O3' DC C 7 -26.566 -1.917 -0.850 1.00 53.91 O ANISOU 1262 O3' DC C 7 5140 9703 5639 1531 -227 -1376 O ATOM 1263 C2' DC C 7 -24.312 -1.054 -1.226 1.00 49.27 C ANISOU 1263 C2' DC C 7 4497 9302 4922 1569 -241 -1090 C ATOM 1264 C1' DC C 7 -24.279 0.034 -0.165 1.00 43.32 C ANISOU 1264 C1' DC C 7 3748 8473 4239 1552 -262 -1015 C ATOM 1265 N1 DC C 7 -23.059 0.883 -0.233 1.00 33.61 N ANISOU 1265 N1 DC C 7 2419 7392 2958 1511 -264 -881 N ATOM 1266 C2 DC C 7 -23.184 2.273 -0.339 1.00 34.23 C ANISOU 1266 C2 DC C 7 2448 7553 3005 1517 -284 -777 C ATOM 1267 O2 DC C 7 -24.313 2.777 -0.371 1.00 34.09 O ANISOU 1267 O2 DC C 7 2518 7445 2990 1602 -322 -783 O ATOM 1268 N3 DC C 7 -22.059 3.028 -0.402 1.00 52.02 N ANISOU 1268 N3 DC C 7 4678 9886 5202 1365 -238 -678 N ATOM 1269 C4 DC C 7 -20.859 2.445 -0.364 1.00 52.33 C ANISOU 1269 C4 DC C 7 4536 10113 5234 1316 -215 -733 C ATOM 1270 N4 DC C 7 -19.778 3.230 -0.429 1.00 50.20 N ANISOU 1270 N4 DC C 7 4219 9942 4914 1107 -141 -697 N ATOM 1271 C5 DC C 7 -20.714 1.031 -0.258 1.00 35.26 C ANISOU 1271 C5 DC C 7 2426 7881 3090 1393 -233 -829 C ATOM 1272 C6 DC C 7 -21.829 0.298 -0.197 1.00 34.10 C ANISOU 1272 C6 DC C 7 2424 7549 2985 1479 -246 -886 C ATOM 1273 P DC C 8 -27.182 -2.398 -2.254 1.00 65.63 P ANISOU 1273 P DC C 8 6560 11337 7041 1544 -258 -1490 P ATOM 1274 OP1 DC C 8 -28.424 -3.148 -1.967 1.00 62.81 O ANISOU 1274 OP1 DC C 8 6175 10898 6794 1450 -220 -1722 O ATOM 1275 OP2 DC C 8 -26.100 -3.039 -3.035 1.00 75.03 O ANISOU 1275 OP2 DC C 8 7740 12627 8141 1566 -239 -1410 O ATOM 1276 O5' DC C 8 -27.562 -1.029 -2.985 1.00 61.31 O ANISOU 1276 O5' DC C 8 5991 10929 6374 1667 -341 -1424 O ATOM 1277 C5' DC C 8 -28.408 -0.096 -2.334 1.00 58.88 C ANISOU 1277 C5' DC C 8 5705 10557 6111 1710 -381 -1451 C ATOM 1278 C4' DC C 8 -28.221 1.293 -2.910 1.00 58.57 C ANISOU 1278 C4' DC C 8 5698 10627 5930 1890 -434 -1293 C ATOM 1279 O4' DC C 8 -26.905 1.770 -2.598 1.00 42.59 O ANISOU 1279 O4' DC C 8 3674 8598 3912 1853 -388 -1081 O ATOM 1280 C3' DC C 8 -28.308 1.375 -4.425 1.00 63.05 C ANISOU 1280 C3' DC C 8 6255 11404 6297 2053 -475 -1308 C ATOM 1281 O3' DC C 8 -29.650 1.638 -4.815 1.00 76.62 O ANISOU 1281 O3' DC C 8 7980 13201 7930 2199 -565 -1493 O ATOM 1282 C2' DC C 8 -27.374 2.545 -4.784 1.00 45.67 C ANISOU 1282 C2' DC C 8 4098 9288 3968 2195 -465 -1060 C ATOM 1283 C1' DC C 8 -26.591 2.809 -3.490 1.00 42.18 C ANISOU 1283 C1' DC C 8 3633 8710 3682 2028 -417 -939 C ATOM 1284 N1 DC C 8 -25.120 2.837 -3.681 1.00 36.90 N ANISOU 1284 N1 DC C 8 2875 8161 2983 1938 -345 -794 N ATOM 1285 C2 DC C 8 -24.478 4.056 -3.913 1.00 38.24 C ANISOU 1285 C2 DC C 8 3263 8239 3025 1851 -278 -594 C ATOM 1286 O2 DC C 8 -25.152 5.093 -3.958 1.00 39.23 O ANISOU 1286 O2 DC C 8 3629 8233 3044 1959 -307 -517 O ATOM 1287 N3 DC C 8 -23.132 4.068 -4.082 1.00 38.80 N ANISOU 1287 N3 DC C 8 3296 8370 3077 1647 -161 -516 N ATOM 1288 C4 DC C 8 -22.442 2.927 -4.025 1.00 38.02 C ANISOU 1288 C4 DC C 8 2943 8436 3066 1603 -151 -615 C ATOM 1289 N4 DC C 8 -21.118 2.986 -4.199 1.00 39.01 N ANISOU 1289 N4 DC C 8 2985 8676 3162 1424 -45 -581 N ATOM 1290 C5 DC C 8 -23.081 1.673 -3.790 1.00 36.60 C ANISOU 1290 C5 DC C 8 2681 8237 2987 1693 -221 -769 C ATOM 1291 C6 DC C 8 -24.408 1.676 -3.624 1.00 36.11 C ANISOU 1291 C6 DC C 8 2723 8042 2957 1780 -287 -851 C ATOM 1292 P DC C 9 -30.138 1.319 -6.313 1.00 76.54 P ANISOU 1292 P DC C 9 7944 13426 7712 2368 -627 -1640 P ATOM 1293 OP1 DC C 9 -31.618 1.327 -6.309 1.00 75.47 O ANISOU 1293 OP1 DC C 9 7757 13376 7541 2442 -725 -1923 O ATOM 1294 OP2 DC C 9 -29.408 0.121 -6.783 1.00 84.83 O ANISOU 1294 OP2 DC C 9 8926 14510 8796 2204 -570 -1646 O ATOM 1295 O5' DC C 9 -29.617 2.572 -7.157 1.00 65.58 O ANISOU 1295 O5' DC C 9 6687 12131 6098 2684 -636 -1422 O ATOM 1296 C5' DC C 9 -30.049 3.883 -6.818 1.00 63.90 C ANISOU 1296 C5' DC C 9 6620 11853 5807 2916 -690 -1331 C ATOM 1297 C4' DC C 9 -29.210 4.928 -7.529 1.00 68.85 C ANISOU 1297 C4' DC C 9 7456 12490 6213 3158 -690 -1037 C ATOM 1298 O4' DC C 9 -27.833 4.827 -7.088 1.00 43.53 O ANISOU 1298 O4' DC C 9 4212 9265 3062 2907 -622 -822 O ATOM 1299 C3' DC C 9 -29.184 4.809 -9.058 1.00 72.50 C ANISOU 1299 C3' DC C 9 7986 13101 6460 3398 -695 -1054 C ATOM 1300 O3' DC C 9 -29.512 6.063 -9.647 1.00 78.79 O ANISOU 1300 O3' DC C 9 9158 13787 6991 3748 -750 -910 O ATOM 1301 C2' DC C 9 -27.743 4.391 -9.370 1.00 56.33 C ANISOU 1301 C2' DC C 9 5902 11115 4385 3187 -606 -864 C ATOM 1302 C1' DC C 9 -26.985 4.984 -8.196 1.00 54.44 C ANISOU 1302 C1' DC C 9 5770 10672 4241 2910 -523 -672 C ATOM 1303 N1 DC C 9 -25.704 4.289 -7.911 1.00 65.98 N ANISOU 1303 N1 DC C 9 7055 12134 5880 2552 -374 -617 N ATOM 1304 C2 DC C 9 -24.542 5.038 -7.699 1.00 55.91 C ANISOU 1304 C2 DC C 9 5980 10686 4576 2286 -193 -413 C ATOM 1305 O2 DC C 9 -24.603 6.273 -7.748 1.00 56.97 O ANISOU 1305 O2 DC C 9 6495 10614 4537 2317 -124 -260 O ATOM 1306 N3 DC C 9 -23.380 4.386 -7.443 1.00 42.93 N ANISOU 1306 N3 DC C 9 4114 9119 3078 2009 -86 -421 N ATOM 1307 C4 DC C 9 -23.358 3.052 -7.398 1.00 41.39 C ANISOU 1307 C4 DC C 9 3591 9109 3026 2027 -148 -578 C ATOM 1308 N4 DC C 9 -22.191 2.454 -7.143 1.00 40.86 N ANISOU 1308 N4 DC C 9 3335 9131 3060 1826 -58 -589 N ATOM 1309 C5 DC C 9 -24.532 2.273 -7.614 1.00 57.28 C ANISOU 1309 C5 DC C 9 5463 11237 5065 2256 -289 -764 C ATOM 1310 C6 DC C 9 -25.671 2.926 -7.866 1.00 71.02 C ANISOU 1310 C6 DC C 9 7347 12953 6684 2495 -401 -798 C ATOM 1311 P DT C 10 -29.402 6.275 -11.237 1.00 82.75 P ANISOU 1311 P DT C 10 9891 14325 7226 4040 -749 -845 P ATOM 1312 OP1 DT C 10 -30.331 7.367 -11.599 1.00 86.17 O ANISOU 1312 OP1 DT C 10 10658 14631 7451 4466 -827 -851 O ATOM 1313 OP2 DT C 10 -29.525 4.955 -11.897 1.00 86.05 O ANISOU 1313 OP2 DT C 10 9934 15000 7763 3987 -747 -1088 O ATOM 1314 O5' DT C 10 -27.907 6.797 -11.445 1.00 77.24 O ANISOU 1314 O5' DT C 10 9559 13460 6328 3803 -572 -498 O ATOM 1315 C5' DT C 10 -27.415 7.862 -10.642 1.00 71.42 C ANISOU 1315 C5' DT C 10 9192 12468 5476 3649 -446 -274 C ATOM 1316 C4' DT C 10 -25.973 8.169 -10.986 1.00 54.13 C ANISOU 1316 C4' DT C 10 7281 10152 3134 3321 -154 -55 C ATOM 1317 O4' DT C 10 -25.123 7.107 -10.494 1.00 53.12 O ANISOU 1317 O4' DT C 10 6662 10166 3354 2912 -94 -134 O ATOM 1318 C3' DT C 10 -25.686 8.291 -12.486 1.00 69.05 C ANISOU 1318 C3' DT C 10 9475 12008 4752 3488 -58 20 C ATOM 1319 O3' DT C 10 -25.159 9.577 -12.781 1.00 78.06 O ANISOU 1319 O3' DT C 10 11281 12779 5599 3426 209 255 O ATOM 1320 C2' DT C 10 -24.668 7.180 -12.776 1.00 64.66 C ANISOU 1320 C2' DT C 10 8544 11703 4320 3183 47 -36 C ATOM 1321 C1' DT C 10 -24.074 6.907 -11.404 1.00 61.91 C ANISOU 1321 C1' DT C 10 7849 11314 4359 2744 104 -59 C ATOM 1322 N1 DT C 10 -23.574 5.516 -11.249 1.00 49.89 N ANISOU 1322 N1 DT C 10 5785 10055 3118 2552 63 -209 N ATOM 1323 C2 DT C 10 -22.243 5.305 -10.984 1.00 49.43 C ANISOU 1323 C2 DT C 10 5581 10004 3196 2157 263 -172 C ATOM 1324 O2 DT C 10 -21.437 6.209 -10.859 1.00 51.01 O ANISOU 1324 O2 DT C 10 6034 10023 3323 1892 492 -51 O ATOM 1325 N3 DT C 10 -21.884 3.988 -10.865 1.00 47.45 N ANISOU 1325 N3 DT C 10 4882 9994 3153 2085 200 -316 N ATOM 1326 C4 DT C 10 -22.708 2.884 -10.986 1.00 45.96 C ANISOU 1326 C4 DT C 10 4422 9990 3049 2306 7 -487 C ATOM 1327 O4 DT C 10 -22.291 1.736 -10.863 1.00 44.55 O ANISOU 1327 O4 DT C 10 3930 9973 3025 2226 1 -600 O ATOM 1328 C5 DT C 10 -24.094 3.176 -11.268 1.00 63.85 C ANISOU 1328 C5 DT C 10 6813 12258 5189 2647 -174 -555 C ATOM 1329 C7 DT C 10 -25.085 2.061 -11.421 1.00 77.74 C ANISOU 1329 C7 DT C 10 8265 14244 7029 2842 -352 -812 C ATOM 1330 C6 DT C 10 -24.455 4.463 -11.386 1.00 64.93 C ANISOU 1330 C6 DT C 10 7354 12202 5115 2783 -159 -416 C ATOM 1331 P DG C 11 -25.424 10.245 -14.217 1.00 70.74 P ANISOU 1331 P DG C 11 10901 11612 4364 3765 261 349 P ATOM 1332 OP1 DG C 11 -24.601 11.473 -14.300 1.00 69.60 O ANISOU 1332 OP1 DG C 11 11437 11040 3967 3513 642 576 O ATOM 1333 OP2 DG C 11 -26.891 10.327 -14.404 1.00 65.72 O ANISOU 1333 OP2 DG C 11 10193 11030 3750 4308 -63 204 O ATOM 1334 O5' DG C 11 -24.861 9.162 -15.250 1.00 74.29 O ANISOU 1334 O5' DG C 11 11068 12324 4836 3698 280 272 O ATOM 1335 C5' DG C 11 -24.136 9.576 -16.400 1.00 86.97 C ANISOU 1335 C5' DG C 11 13144 13727 6174 3642 541 409 C ATOM 1336 C4' DG C 11 -22.640 9.574 -16.129 1.00 93.31 C ANISOU 1336 C4' DG C 11 13964 14513 6978 3061 933 491 C ATOM 1337 O4' DG C 11 -22.311 8.501 -15.206 1.00 83.72 O ANISOU 1337 O4' DG C 11 12049 13685 6078 2825 833 347 O ATOM 1338 C3' DG C 11 -21.766 9.361 -17.367 1.00 96.94 C ANISOU 1338 C3' DG C 11 14604 14953 7276 2920 1182 529 C ATOM 1339 O3' DG C 11 -20.691 10.291 -17.380 1.00 91.23 O ANISOU 1339 O3' DG C 11 14353 13926 6386 2479 1657 652 O ATOM 1340 C2' DG C 11 -21.268 7.925 -17.215 1.00 87.87 C ANISOU 1340 C2' DG C 11 12728 14262 6397 2746 1090 368 C ATOM 1341 C1' DG C 11 -21.216 7.768 -15.705 1.00 79.85 C ANISOU 1341 C1' DG C 11 11299 13377 5663 2519 1019 303 C ATOM 1342 N9 DG C 11 -21.345 6.380 -15.267 1.00 73.74 N ANISOU 1342 N9 DG C 11 9810 12963 5247 2505 761 116 N ATOM 1343 C8 DG C 11 -22.501 5.640 -15.194 1.00 69.79 C ANISOU 1343 C8 DG C 11 9017 12664 4838 2864 410 -28 C ATOM 1344 N7 DG C 11 -22.312 4.421 -14.772 1.00 70.88 N ANISOU 1344 N7 DG C 11 8603 13059 5271 2732 308 -184 N ATOM 1345 C5 DG C 11 -20.942 4.344 -14.553 1.00 69.81 C ANISOU 1345 C5 DG C 11 8353 12909 5262 2308 558 -138 C ATOM 1346 C6 DG C 11 -20.151 3.264 -14.090 1.00 57.15 C ANISOU 1346 C6 DG C 11 6259 11518 3936 2072 567 -257 C ATOM 1347 O6 DG C 11 -20.517 2.124 -13.773 1.00 49.62 O ANISOU 1347 O6 DG C 11 4934 10751 3168 2171 385 -402 O ATOM 1348 N1 DG C 11 -18.804 3.608 -14.011 1.00 53.15 N ANISOU 1348 N1 DG C 11 5742 10996 3455 1694 842 -220 N ATOM 1349 C2 DG C 11 -18.286 4.840 -14.337 1.00 62.19 C ANISOU 1349 C2 DG C 11 7319 11914 4398 1489 1127 -96 C ATOM 1350 N2 DG C 11 -16.960 4.983 -14.196 1.00 64.59 N ANISOU 1350 N2 DG C 11 7484 12286 4772 1072 1399 -152 N ATOM 1351 N3 DG C 11 -19.016 5.861 -14.772 1.00 69.66 N ANISOU 1351 N3 DG C 11 8815 12588 5066 1689 1162 45 N ATOM 1352 C4 DG C 11 -20.331 5.542 -14.855 1.00 73.40 C ANISOU 1352 C4 DG C 11 9282 13107 5498 2132 844 22 C ATOM 1353 P DC C 12 -19.915 10.602 -18.752 1.00 86.82 P ANISOU 1353 P DC C 12 14258 13155 5575 2336 2000 720 P ATOM 1354 OP1 DC C 12 -19.175 11.871 -18.573 1.00 87.39 O ANISOU 1354 OP1 DC C 12 14901 12804 5498 1913 2461 821 O ATOM 1355 OP2 DC C 12 -20.886 10.466 -19.861 1.00 85.25 O ANISOU 1355 OP2 DC C 12 14256 12908 5226 2913 1709 737 O ATOM 1356 O5' DC C 12 -18.862 9.405 -18.875 1.00 90.16 O ANISOU 1356 O5' DC C 12 14079 14001 6177 1998 2120 585 O ATOM 1357 C5' DC C 12 -17.893 9.211 -17.854 1.00 96.28 C ANISOU 1357 C5' DC C 12 14430 14979 7172 1504 2332 493 C ATOM 1358 C4' DC C 12 -17.134 7.914 -18.068 1.00 95.56 C ANISOU 1358 C4' DC C 12 13646 15306 7356 1322 2279 327 C ATOM 1359 O4' DC C 12 -17.858 6.819 -17.477 1.00 90.18 O ANISOU 1359 O4' DC C 12 12358 14936 6970 1598 1815 226 O ATOM 1360 C3' DC C 12 -16.918 7.524 -19.532 1.00 88.84 C ANISOU 1360 C3' DC C 12 13000 14489 6266 1473 2389 347 C ATOM 1361 O3' DC C 12 -15.558 7.726 -19.888 1.00 99.83 O ANISOU 1361 O3' DC C 12 14435 15886 7612 964 2870 287 O ATOM 1362 C2' DC C 12 -17.311 6.034 -19.602 1.00 80.96 C ANISOU 1362 C2' DC C 12 11340 13891 5532 1737 1978 219 C ATOM 1363 C1' DC C 12 -17.474 5.646 -18.136 1.00 79.19 C ANISOU 1363 C1' DC C 12 10570 13858 5660 1639 1753 121 C ATOM 1364 N1 DC C 12 -18.515 4.605 -17.902 1.00 70.79 N ANISOU 1364 N1 DC C 12 9109 13023 4764 2023 1311 30 N ATOM 1365 C2 DC C 12 -18.149 3.374 -17.345 1.00 58.48 C ANISOU 1365 C2 DC C 12 6918 11767 3537 1911 1173 -127 C ATOM 1366 O2 DC C 12 -16.964 3.173 -17.055 1.00 58.65 O ANISOU 1366 O2 DC C 12 6681 11905 3700 1553 1371 -191 O ATOM 1367 N3 DC C 12 -19.106 2.437 -17.137 1.00 55.95 N ANISOU 1367 N3 DC C 12 6303 11565 3392 2187 828 -228 N ATOM 1368 C4 DC C 12 -20.373 2.693 -17.464 1.00 56.34 C ANISOU 1368 C4 DC C 12 6566 11514 3326 2548 608 -217 C ATOM 1369 N4 DC C 12 -21.281 1.737 -17.240 1.00 54.24 N ANISOU 1369 N4 DC C 12 5958 11395 3256 2744 320 -374 N ATOM 1370 C5 DC C 12 -20.766 3.941 -18.034 1.00 59.37 C ANISOU 1370 C5 DC C 12 7538 11624 3396 2721 687 -68 C ATOM 1371 C6 DC C 12 -19.814 4.858 -18.233 1.00 61.81 C ANISOU 1371 C6 DC C 12 8233 11745 3507 2454 1046 70 C ATOM 1372 P DT C 13 -15.079 7.524 -21.407 1.00118.98 P ANISOU 1372 P DT C 13 17137 18234 9835 947 3079 293 P ATOM 1373 OP1 DT C 13 -13.914 8.408 -21.629 1.00128.74 O ANISOU 1373 OP1 DT C 13 18688 19276 10950 373 3648 256 O ATOM 1374 OP2 DT C 13 -16.269 7.637 -22.280 1.00122.93 O ANISOU 1374 OP2 DT C 13 18061 18508 10137 1501 2765 425 O ATOM 1375 O5' DT C 13 -14.582 6.006 -21.448 1.00108.72 O ANISOU 1375 O5' DT C 13 15038 17428 8842 937 2892 121 O ATOM 1376 C5' DT C 13 -13.641 5.545 -20.488 1.00 97.44 C ANISOU 1376 C5' DT C 13 12946 16324 7752 545 2949 -64 C ATOM 1377 C4' DT C 13 -13.399 4.058 -20.648 1.00 89.57 C ANISOU 1377 C4' DT C 13 11317 15663 7054 672 2666 -197 C ATOM 1378 O4' DT C 13 -14.504 3.320 -20.069 1.00 80.89 O ANISOU 1378 O4' DT C 13 9941 14676 6119 1073 2182 -182 O ATOM 1379 C3' DT C 13 -13.274 3.583 -22.099 1.00 91.91 C ANISOU 1379 C3' DT C 13 11817 15920 7183 820 2739 -167 C ATOM 1380 O3' DT C 13 -12.085 2.824 -22.265 1.00 98.98 O ANISOU 1380 O3' DT C 13 12259 17046 8303 553 2862 -335 O ATOM 1381 C2' DT C 13 -14.525 2.729 -22.320 1.00 84.88 C ANISOU 1381 C2' DT C 13 10820 15096 6336 1344 2255 -118 C ATOM 1382 C1' DT C 13 -14.835 2.247 -20.913 1.00 80.63 C ANISOU 1382 C1' DT C 13 9768 14748 6121 1361 1961 -202 C ATOM 1383 N1 DT C 13 -16.271 1.907 -20.708 1.00 63.11 N ANISOU 1383 N1 DT C 13 7542 12514 3924 1791 1556 -170 N ATOM 1384 C2 DT C 13 -16.603 0.722 -20.092 1.00 59.77 C ANISOU 1384 C2 DT C 13 6614 12297 3801 1901 1250 -290 C ATOM 1385 O2 DT C 13 -15.775 -0.077 -19.692 1.00 58.66 O ANISOU 1385 O2 DT C 13 6072 12319 3895 1716 1254 -392 O ATOM 1386 N3 DT C 13 -17.948 0.505 -19.957 1.00 58.23 N ANISOU 1386 N3 DT C 13 6428 12083 3616 2239 939 -304 N ATOM 1387 C4 DT C 13 -18.975 1.336 -20.370 1.00 59.72 C ANISOU 1387 C4 DT C 13 7028 12096 3568 2525 851 -224 C ATOM 1388 O4 DT C 13 -20.157 1.052 -20.203 1.00 58.56 O ANISOU 1388 O4 DT C 13 6781 11985 3482 2812 559 -300 O ATOM 1389 C5 DT C 13 -18.557 2.561 -21.011 1.00 63.23 C ANISOU 1389 C5 DT C 13 8044 12288 3693 2456 1141 -68 C ATOM 1390 C7 DT C 13 -19.580 3.542 -21.503 1.00 66.79 C ANISOU 1390 C7 DT C 13 9037 12473 3867 2804 1047 37 C ATOM 1391 C6 DT C 13 -17.242 2.783 -21.148 1.00 64.73 C ANISOU 1391 C6 DT C 13 8270 12472 3851 2071 1503 -46 C ATOM 1392 P DG C 14 -11.437 2.649 -23.724 1.00115.34 P ANISOU 1392 P DG C 14 14584 19049 10191 487 3154 -339 P ATOM 1393 OP1 DG C 14 -10.015 3.047 -23.633 1.00117.99 O ANISOU 1393 OP1 DG C 14 14781 19418 10631 -17 3574 -491 O ATOM 1394 OP2 DG C 14 -12.329 3.319 -24.699 1.00120.50 O ANISOU 1394 OP2 DG C 14 15968 19384 10432 753 3207 -150 O ATOM 1395 O5' DG C 14 -11.488 1.071 -23.974 1.00101.38 O ANISOU 1395 O5' DG C 14 12294 17559 8667 753 2783 -416 O ATOM 1396 C5' DG C 14 -10.837 0.193 -23.066 1.00 85.08 C ANISOU 1396 C5' DG C 14 9580 15772 6974 652 2594 -581 C ATOM 1397 C4' DG C 14 -11.424 -1.203 -23.146 1.00 71.52 C ANISOU 1397 C4' DG C 14 7569 14196 5408 1013 2177 -587 C ATOM 1398 O4' DG C 14 -12.814 -1.176 -22.721 1.00 72.65 O ANISOU 1398 O4' DG C 14 7822 14260 5520 1319 1876 -492 O ATOM 1399 C3' DG C 14 -11.420 -1.832 -24.541 1.00 69.55 C ANISOU 1399 C3' DG C 14 7475 13933 5020 1172 2212 -555 C ATOM 1400 O3' DG C 14 -11.054 -3.200 -24.445 1.00 82.60 O ANISOU 1400 O3' DG C 14 8709 15776 6901 1266 1984 -655 O ATOM 1401 C2' DG C 14 -12.870 -1.676 -24.990 1.00 67.83 C ANISOU 1401 C2' DG C 14 7599 13571 4602 1535 2000 -422 C ATOM 1402 C1' DG C 14 -13.598 -1.858 -23.671 1.00 70.09 C ANISOU 1402 C1' DG C 14 7616 13918 5096 1640 1692 -446 C ATOM 1403 N9 DG C 14 -14.946 -1.298 -23.656 1.00 74.41 N ANISOU 1403 N9 DG C 14 8459 14329 5485 1920 1517 -354 N ATOM 1404 C8 DG C 14 -15.330 -0.048 -24.078 1.00 77.15 C ANISOU 1404 C8 DG C 14 9342 14446 5525 1972 1675 -230 C ATOM 1405 N7 DG C 14 -16.607 0.177 -23.942 1.00 65.55 N ANISOU 1405 N7 DG C 14 8015 12903 3987 2299 1404 -192 N ATOM 1406 C5 DG C 14 -17.103 -0.999 -23.393 1.00 73.23 C ANISOU 1406 C5 DG C 14 8500 14081 5243 2417 1091 -316 C ATOM 1407 C6 DG C 14 -18.424 -1.348 -23.024 1.00 60.44 C ANISOU 1407 C6 DG C 14 6749 12508 3708 2706 754 -389 C ATOM 1408 O6 DG C 14 -19.453 -0.662 -23.113 1.00 61.32 O ANISOU 1408 O6 DG C 14 7110 12516 3675 2966 620 -362 O ATOM 1409 N1 DG C 14 -18.491 -2.639 -22.505 1.00 57.75 N ANISOU 1409 N1 DG C 14 5956 12335 3650 2669 577 -524 N ATOM 1410 C2 DG C 14 -17.417 -3.486 -22.362 1.00 56.96 C ANISOU 1410 C2 DG C 14 5601 12321 3718 2445 664 -561 C ATOM 1411 N2 DG C 14 -17.677 -4.694 -21.842 1.00 54.71 N ANISOU 1411 N2 DG C 14 5027 12107 3652 2453 464 -673 N ATOM 1412 N3 DG C 14 -16.174 -3.172 -22.703 1.00 58.67 N ANISOU 1412 N3 DG C 14 5878 12534 3879 2221 935 -508 N ATOM 1413 C4 DG C 14 -16.092 -1.917 -23.210 1.00 67.83 C ANISOU 1413 C4 DG C 14 7445 13552 4776 2193 1158 -397 C ATOM 1414 P DG C 15 -10.282 -3.925 -25.654 1.00 95.70 P ANISOU 1414 P DG C 15 10353 17498 8512 1255 2122 -699 P ATOM 1415 OP1 DG C 15 -8.872 -4.100 -25.241 1.00 97.91 O ANISOU 1415 OP1 DG C 15 10291 17946 8967 987 2262 -859 O ATOM 1416 OP2 DG C 15 -10.600 -3.193 -26.901 1.00 96.61 O ANISOU 1416 OP2 DG C 15 10980 17424 8303 1282 2372 -588 O ATOM 1417 O5' DG C 15 -10.980 -5.360 -25.739 1.00 79.43 O ANISOU 1417 O5' DG C 15 8115 15506 6560 1578 1739 -701 O ATOM 1418 C5' DG C 15 -11.131 -6.145 -24.563 1.00 63.34 C ANISOU 1418 C5' DG C 15 5773 13544 4750 1651 1444 -764 C ATOM 1419 C4' DG C 15 -12.367 -7.022 -24.655 1.00 75.73 C ANISOU 1419 C4' DG C 15 7383 15059 6330 1929 1148 -736 C ATOM 1420 O4' DG C 15 -13.556 -6.215 -24.453 1.00 65.05 O ANISOU 1420 O4' DG C 15 6213 13612 4891 2035 1074 -669 O ATOM 1421 C3' DG C 15 -12.552 -7.739 -25.994 1.00 82.06 C ANISOU 1421 C3' DG C 15 8301 15863 7014 2075 1154 -724 C ATOM 1422 O3' DG C 15 -12.842 -9.111 -25.771 1.00 90.31 O ANISOU 1422 O3' DG C 15 9213 16923 8177 2198 928 -787 O ATOM 1423 C2' DG C 15 -13.732 -7.008 -26.641 1.00 64.84 C ANISOU 1423 C2' DG C 15 6410 13592 4634 2244 1129 -650 C ATOM 1424 C1' DG C 15 -14.518 -6.537 -25.428 1.00 60.23 C ANISOU 1424 C1' DG C 15 5767 12971 4145 2267 967 -651 C ATOM 1425 N9 DG C 15 -15.319 -5.344 -25.683 1.00 61.32 N ANISOU 1425 N9 DG C 15 6205 13013 4080 2377 1003 -572 N ATOM 1426 C8 DG C 15 -14.863 -4.122 -26.107 1.00 63.93 C ANISOU 1426 C8 DG C 15 6865 13233 4194 2268 1282 -475 C ATOM 1427 N7 DG C 15 -15.806 -3.233 -26.248 1.00 64.74 N ANISOU 1427 N7 DG C 15 7289 13208 4102 2453 1227 -404 N ATOM 1428 C5 DG C 15 -16.966 -3.909 -25.894 1.00 66.84 C ANISOU 1428 C5 DG C 15 7346 13557 4494 2694 885 -489 C ATOM 1429 C6 DG C 15 -18.307 -3.459 -25.853 1.00 62.54 C ANISOU 1429 C6 DG C 15 6936 12970 3857 2982 666 -505 C ATOM 1430 O6 DG C 15 -18.748 -2.334 -26.132 1.00 64.59 O ANISOU 1430 O6 DG C 15 7586 13073 3882 3132 701 -414 O ATOM 1431 N1 DG C 15 -19.176 -4.465 -25.439 1.00 60.33 N ANISOU 1431 N1 DG C 15 6313 12829 3780 3095 391 -662 N ATOM 1432 C2 DG C 15 -18.797 -5.745 -25.106 1.00 58.37 C ANISOU 1432 C2 DG C 15 5740 12680 3759 2945 338 -754 C ATOM 1433 N2 DG C 15 -19.779 -6.577 -24.729 1.00 56.87 N ANISOU 1433 N2 DG C 15 5337 12564 3708 3021 108 -912 N ATOM 1434 N3 DG C 15 -17.543 -6.180 -25.140 1.00 68.84 N ANISOU 1434 N3 DG C 15 6990 14011 5154 2729 508 -711 N ATOM 1435 C4 DG C 15 -16.684 -5.211 -25.542 1.00 60.40 C ANISOU 1435 C4 DG C 15 6150 12873 3925 2617 771 -593 C TER 1436 DG C 15 HETATM 1437 ZN ZN A 501 -19.101 21.927 -2.225 1.00 72.37 ZN HETATM 1438 ZN ZN A 502 -3.719 -1.015 -7.031 1.00 76.90 ZN HETATM 1439 ZN ZN A 503 -26.831 -14.767 -12.883 1.00 62.94 ZN HETATM 1440 ZN ZN A 504 -30.674 9.288 -29.785 1.00 82.62 ZN HETATM 1441 O HOH A 601 -26.266 9.614 8.555 1.00 26.75 O HETATM 1442 O HOH A 602 -24.030 30.364 -3.581 1.00 0.66 O HETATM 1443 O HOH A 603 -26.091 13.814 5.545 1.00 4.76 O HETATM 1444 O HOH B 101 -12.636 -2.533 -16.932 1.00 19.87 O HETATM 1445 O HOH C 102 -14.251 4.640 -14.682 1.00 2.87 O HETATM 1446 O HOH C 103 -17.497 2.263 -27.431 1.00 5.44 O CONECT 33 1437 CONECT 53 1437 CONECT 160 1437 CONECT 195 1437 CONECT 259 1438 CONECT 279 1438 CONECT 393 1438 CONECT 429 1438 CONECT 491 1439 CONECT 517 1439 CONECT 622 1439 CONECT 666 1439 CONECT 738 1440 CONECT 761 1440 CONECT 859 1440 CONECT 906 1440 CONECT 1437 33 53 160 195 CONECT 1438 259 279 393 429 CONECT 1439 491 517 622 666 CONECT 1440 738 761 859 906 MASTER 405 0 4 4 4 0 5 6 1443 3 20 12 END
Display Options:
Goto PDB code:
3D presentation of molecule is powered by
3Dmol
, which supports all modern browsers and mobile devices via WebGL.
Hold mouse button:
left to rotate,middle to shift,right to zoom
Related entries of code: 5k5h
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5kkq
RCSB PDB
PDBbind
17aa, >5KKQ_3|Chains... *
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
5kkq
RCSB PDB
PDBbind
oligo DNA containing the CORE sequence
Entry Information
PDB ID
5k5h
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Homo sapiens CCCTC-binding factor (CTCF) ZnF4-7
Ligand Name
oligo DNA containing the CORE sequence
EC.Number
E.C.-.-.-.-
Resolution
3.11(Å)
Affinity (Kd/Ki/IC50)
Kd=30nM
Release Year
2017
Protein/NA Sequence
Check fasta file
Primary Reference
(2017) Mol. Cell Vol. 66: pp. 711-720.e3
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P49711
Entrez Gene ID
NCBI Entrez Gene ID:
10664
ASD
Information of known allosteric effects of PDB entries
This site has been visited
times since Nov 2007.
Copyright ©2007-2024 涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃 缃戠珯澶囨鍙凤細
娌狪CP澶2021015625鍙-3
娌叕缃戝畨澶囷細
姝ｅ湪鐢宠涓
Technical Support锛堟妧鏈敮鎸侊級:
yingsaisi@foxmail.com
times since Nov 2007. 
娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓