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Related entries of code: 5l4h
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3p4wRCSB PDB    PDBbind318aa, >3P4W_1|Chains... *
3p50RCSB PDB    PDBbind318aa, >3P50_1|Chains... at 100%
4f8hRCSB PDB    PDBbind317aa, >4F8H_1|Chains... at 99%
5l4eRCSB PDB    PDBbind317aa, >5L4E_1|Chains... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5l4h
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Name2-22' locally-closed mutant of GLIC
Ligand Name6JW
EC.Number E.C.-.-.-.-
Resolution 3.3(Å)
Affinity (Kd/Ki/IC50)IC50=177uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Biol. Chem. Vol. 292: pp. 1550-1558
Ligand Properties
Formula C8H11BrN2O3
Molecular Weight 263.089
Exact Mass 261.995
No. of atoms 25
No. of bonds 25
Polar Surface Area 75.27
LOGP Value 0.70      (Computed with XLOGP3)
1.19      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 3
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 1
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q7NDN8  
Entrez Gene IDNo matched NCBI Entrez Gene ID found!
ASDInformation of known allosteric effects of PDB entries
 
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