Browse entries in the PDBbind-CN Database

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Related entries of code: 5lxp
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4f1lRCSB PDB    PDBbind193aa, >4F1L_1|Chains... at 98%
4f1qRCSB PDB    PDBbind193aa, >4F1Q_1|Chains... at 98%
4py4RCSB PDB    PDBbind189aa, >4PY4_1|Chains... at 100%
5lyhRCSB PDB    PDBbind193aa, >5LYH_1|Chains... at 98%
5nqeRCSB PDB    PDBbind193aa, >5NQE_1|Chains... at 98%
5v7tRCSB PDB    PDBbind194aa, >5V7T_1|Chain... *
5v7wRCSB PDB    PDBbind194aa, >5V7W_1|Chains... at 100%
6g0wRCSB PDB    PDBbind193aa, >6G0W_1|Chains... at 98%
6fzmRCSB PDB    PDBbind193aa, >6FZM_1|Chains... at 98%
6fymRCSB PDB    PDBbind193aa, >6FYM_1|Chains... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5lxp
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHuman PARP14 (ARTD8), catalytic fragment
Ligand Name7AG
EC.Number E.C.2.4.2.30
Resolution 2.07(Å)
Affinity (Kd/Ki/IC50)IC50=0.76uM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2017) Angew. Chem. Int. Ed. Engl. Vol. 56: pp. 248-253
Ligand Properties
Formula C24H28N6O3
Molecular Weight 448.518
Exact Mass 448.222
No. of atoms 61
No. of bonds 63
Polar Surface Area 132
LOGP Value 1.03      (Computed with XLOGP3)
3.77      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 13
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q460N5  
Entrez Gene IDNCBI Entrez Gene ID: 54625  
ASDInformation of known allosteric effects of PDB entries
 
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