Browse entries in the PDBbind-CN Database
HEADER TRANSFERASE 15-JUN-17 5O90 TITLE CRYSTAL STRUCTURE OF A P38ALPHA T185G MUTANT IN COMPLEX WITH TAB1 TITLE 2 PEPTIDE. COMPND MOL_ID: 1; COMPND 2 MOLECULE: MITOGEN-ACTIVATED PROTEIN KINASE 14; COMPND 3 CHAIN: A; COMPND 4 SYNONYM: MAPK 14,CRK1,MITOGEN-ACTIVATED PROTEIN KINASE P38 ALPHA,MAP COMPND 5 KINASE P38 ALPHA; COMPND 6 EC: 2.7.11.24; COMPND 7 ENGINEERED: YES; COMPND 8 MUTATION: YES; COMPND 9 MOL_ID: 2; COMPND 10 MOLECULE: TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1; COMPND 11 CHAIN: B; COMPND 12 FRAGMENT: UNP RESIDUES 386-414; COMPND 13 SYNONYM: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING COMPND 14 PROTEIN 1,TGF-BETA-ACTIVATED KINASE 1-BINDING PROTEIN 1,TAK1-BINDING COMPND 15 PROTEIN 1; COMPND 16 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: MUS MUSCULUS; SOURCE 3 ORGANISM_COMMON: MOUSE; SOURCE 4 ORGANISM_TAXID: 10090; SOURCE 5 GENE: MAPK14, CRK1, CSBP1, CSBP2; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21(DE3); SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_VARIANT: ROSETTA 2; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 MOL_ID: 2; SOURCE 11 SYNTHETIC: YES; SOURCE 12 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 13 ORGANISM_COMMON: HUMAN; SOURCE 14 ORGANISM_TAXID: 9606 KEYWDS MAPK14 TRANSFERASE TAB1, TRANSFERASE EXPDTA X-RAY DIFFRACTION AUTHOR C.E.NICHOLS,G.F.DE NICOLA,D.THAPA REVDAT 2 21-FEB-18 5O90 1 JRNL REVDAT 1 31-JAN-18 5O90 0 JRNL AUTH D.THAPA,C.NICHOLS,R.BASSI,E.D.MARTIN,S.VERMA,M.R.CONTE, JRNL AUTH 2 V.DE SANTIS,G.F.DE NICOLA,M.S.MARBER JRNL TITL TAB1-INDUCED AUTOACTIVATION OF P38 ALPHA MITOGEN-ACTIVATED JRNL TITL 2 PROTEIN KINASE IS CRUCIALLY DEPENDENT ON THREONINE 185. JRNL REF MOL. CELL. BIOL. V. 38 2018 JRNL REFN ESSN 1098-5549 JRNL PMID 29229647 JRNL DOI 10.1128/MCB.00409-17 REMARK 2 REMARK 2 RESOLUTION. 2.49 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (1.11.1_2575: ???) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.49 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 58.96 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.060 REMARK 3 COMPLETENESS FOR RANGE (%) : 99.6 REMARK 3 NUMBER OF REFLECTIONS : 13808 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.250 REMARK 3 R VALUE (WORKING SET) : 0.249 REMARK 3 FREE R VALUE : 0.275 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.470 REMARK 3 FREE R VALUE TEST SET COUNT : 617 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 58.9758 - 3.9525 1.00 3356 143 0.2136 0.2179 REMARK 3 2 3.9525 - 3.1372 1.00 3293 171 0.2720 0.3194 REMARK 3 3 3.1372 - 2.7407 0.99 3287 139 0.3266 0.3704 REMARK 3 4 2.7407 - 2.4901 0.99 3255 164 0.3506 0.4447 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.420 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 39.300 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 67.90 REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.010 2662 REMARK 3 ANGLE : 1.179 3650 REMARK 3 CHIRALITY : 0.060 418 REMARK 3 PLANARITY : 0.008 473 REMARK 3 DIHEDRAL : 8.015 2034 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 5O90 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 15-JUN-17. REMARK 100 THE DEPOSITION ID IS D_1200005376. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 31-JAN-16 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 7.0 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : DIAMOND REMARK 200 BEAMLINE : I02 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9795 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS3 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XIA2 REMARK 200 DATA SCALING SOFTWARE : XIA2 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 18410 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.260 REMARK 200 RESOLUTION RANGE LOW (A) : 58.960 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.5 REMARK 200 DATA REDUNDANCY : 9.400 REMARK 200 R MERGE (I) : 0.05400 REMARK 200 R SYM (I) : NULL REMARK 200
FOR THE DATA SET : 22.0000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.26 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.32 REMARK 200 COMPLETENESS FOR SHELL (%) : 93.6 REMARK 200 DATA REDUNDANCY IN SHELL : 3.70 REMARK 200 R MERGE FOR SHELL (I) : 0.85200 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200
FOR SHELL : 1.100 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: 4LOO REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 45.12 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.24 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 20% PEG3350 0.2M NA/K TARTRATE 0.1M REMARK 280 PH7.0 BIS-TRIS PROPANE, VAPOR DIFFUSION, HANGING DROP, REMARK 280 TEMPERATURE 277K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1 21 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 36.79000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: DIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 2740 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 16180 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -22.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 SER A 2 REMARK 465 GLN A 3 REMARK 465 GLU A 4 REMARK 465 ARG A 173 REMARK 465 HIS A 174 REMARK 465 THR A 175 REMARK 465 ASP A 176 REMARK 465 ASP A 177 REMARK 465 GLU A 178 REMARK 465 MET A 179 REMARK 465 THR A 180 REMARK 465 GLY A 181 REMARK 465 SER A 251 REMARK 465 SER A 252 REMARK 465 GLU A 253 REMARK 465 SER A 254 REMARK 465 ALA A 255 REMARK 465 ARG A 256 REMARK 465 ASN A 257 REMARK 465 TYR A 258 REMARK 465 ILE A 259 REMARK 465 GLN A 260 REMARK 465 ASP A 354 REMARK 465 GLN A 355 REMARK 465 GLU A 356 REMARK 465 GLU A 357 REMARK 465 MET A 358 REMARK 465 GLU A 359 REMARK 465 SER A 360 REMARK 465 ALA B 395 REMARK 465 GLN B 396 REMARK 465 SER B 397 REMARK 465 THR B 398 REMARK 465 SER B 399 REMARK 465 LYS B 400 REMARK 465 THR B 401 REMARK 465 SER B 402 REMARK 465 SER B 411 REMARK 465 GLN B 412 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 ARG A 10 CG CD NE CZ NH1 NH2 REMARK 470 GLN A 11 CG CD OE1 NE2 REMARK 470 GLU A 12 CG CD OE1 OE2 REMARK 470 LEU A 13 CG CD1 CD2 REMARK 470 ASN A 14 CG OD1 ND2 REMARK 470 LYS A 15 CG CD CE NZ REMARK 470 ILE A 17 CG1 CG2 CD1 REMARK 470 GLU A 19 CG CD OE1 OE2 REMARK 470 GLU A 22 CG CD OE1 OE2 REMARK 470 LEU A 27 CD1 CD2 REMARK 470 VAL A 30 CG1 CG2 REMARK 470 LYS A 45 CD CE NZ REMARK 470 ARG A 49 CD NE CZ NH1 NH2 REMARK 470 LYS A 54 CG CD CE NZ REMARK 470 ARG A 57 CG CD NE CZ NH1 NH2 REMARK 470 GLN A 60 OE1 NE2 REMARK 470 ILE A 62 CG1 CG2 CD1 REMARK 470 ILE A 63 CD1 REMARK 470 LYS A 66 CG CD CE NZ REMARK 470 ARG A 67 CG CD NE CZ NH1 NH2 REMARK 470 LYS A 79 CE NZ REMARK 470 ARG A 94 CG CD NE CZ NH1 NH2 REMARK 470 LEU A 96 CD1 CD2 REMARK 470 LYS A 118 CG CD CE NZ REMARK 470 LYS A 121 CG CD CE NZ REMARK 470 LYS A 139 CD CE NZ REMARK 470 ILE A 141 CD1 REMARK 470 ASP A 145 CG OD1 OD2 REMARK 470 ILE A 147 CD1 REMARK 470 GLU A 160 CG CD OE1 OE2 REMARK 470 VAL A 183 CG1 CG2 REMARK 470 ILE A 193 CD1 REMARK 470 MET A 194 CG SD CE REMARK 470 LEU A 195 CG CD1 CD2 REMARK 470 MET A 198 SD CE REMARK 470 TYR A 200 CG CD1 CD2 CE1 CE2 CZ OH REMARK 470 ARG A 220 CG CD NE CZ NH1 NH2 REMARK 470 HIS A 228 CG ND1 CD2 CE1 NE2 REMARK 470 ILE A 229 CG1 CG2 CD1 REMARK 470 LEU A 232 CG CD1 CD2 REMARK 470 LYS A 233 CG CD CE NZ REMARK 470 LEU A 234 CD1 CD2 REMARK 470 LEU A 236 CG CD1 CD2 REMARK 470 ARG A 237 CG CD NE CZ NH1 NH2 REMARK 470 LEU A 238 CD1 CD2 REMARK 470 LEU A 246 CG CD1 CD2 REMARK 470 LEU A 247 CG CD1 CD2 REMARK 470 LYS A 248 CG CD CE NZ REMARK 470 LYS A 249 CG CD CE NZ REMARK 470 ILE A 250 CG1 CG2 CD1 REMARK 470 LEU A 262 CG CD1 CD2 REMARK 470 GLN A 264 CG CD OE1 NE2 REMARK 470 LYS A 267 CG CD CE NZ REMARK 470 ILE A 275 CG1 CG2 CD1 REMARK 470 LEU A 280 CD1 CD2 REMARK 470 GLU A 286 CG CD OE1 OE2 REMARK 470 LYS A 287 CG CD CE NZ REMARK 470 VAL A 290 CG1 CG2 REMARK 470 ASP A 292 CG OD1 OD2 REMARK 470 ASP A 294 CG OD1 OD2 REMARK 470 LYS A 295 CG CD CE NZ REMARK 470 ASP A 315 CG OD1 OD2 REMARK 470 ASP A 331 OD1 OD2 REMARK 470 LEU A 333 CG CD1 CD2 REMARK 470 ASP A 335 CG OD1 OD2 REMARK 470 LYS A 338 CG CD CE NZ REMARK 470 LEU A 340 CD1 CD2 REMARK 470 VAL A 349 CG1 CG2 REMARK 470 LEU A 353 CG CD1 CD2 REMARK 470 ARG B 384 CG CD NE CZ NH1 NH2 REMARK 470 SER B 393 OG REMARK 470 VAL B 403 CG1 CG2 REMARK 470 LEU B 405 CD1 CD2 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 NZ LYS A 53 OE2 GLU A 71 2.12 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 GLN A 11 138.04 -171.41 REMARK 500 GLN A 60 -81.58 -70.86 REMARK 500 ASN A 100 -35.14 -136.52 REMARK 500 ARG A 149 -2.15 71.21 REMARK 500 PRO A 224 59.43 -69.95 REMARK 500 ALA A 244 -71.20 -63.55 REMARK 500 GLU A 245 -95.67 -52.06 REMARK 500 LEU A 246 -88.67 56.56 REMARK 500 LYS A 249 32.40 -168.99 REMARK 500 LEU A 289 46.63 -94.66 REMARK 500 REMARK 500 REMARK: NULL REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue SB4 A 401 DBREF 5O90 A 1 360 UNP P47811 MK14_MOUSE 1 360 DBREF 5O90 B 384 412 UNP Q15750 TAB1_HUMAN 386 414 SEQADV 5O90 GLY A 185 UNP P47811 THR 185 ENGINEERED MUTATION SEQRES 1 A 360 MET SER GLN GLU ARG PRO THR PHE TYR ARG GLN GLU LEU SEQRES 2 A 360 ASN LYS THR ILE TRP GLU VAL PRO GLU ARG TYR GLN ASN SEQRES 3 A 360 LEU SER PRO VAL GLY SER GLY ALA TYR GLY SER VAL CYS SEQRES 4 A 360 ALA ALA PHE ASP THR LYS THR GLY HIS ARG VAL ALA VAL SEQRES 5 A 360 LYS LYS LEU SER ARG PRO PHE GLN SER ILE ILE HIS ALA SEQRES 6 A 360 LYS ARG THR TYR ARG GLU LEU ARG LEU LEU LYS HIS MET SEQRES 7 A 360 LYS HIS GLU ASN VAL ILE GLY LEU LEU ASP VAL PHE THR SEQRES 8 A 360 PRO ALA ARG SER LEU GLU GLU PHE ASN ASP VAL TYR LEU SEQRES 9 A 360 VAL THR HIS LEU MET GLY ALA ASP LEU ASN ASN ILE VAL SEQRES 10 A 360 LYS CYS GLN LYS LEU THR ASP ASP HIS VAL GLN PHE LEU SEQRES 11 A 360 ILE TYR GLN ILE LEU ARG GLY LEU LYS TYR ILE HIS SER SEQRES 12 A 360 ALA ASP ILE ILE HIS ARG ASP LEU LYS PRO SER ASN LEU SEQRES 13 A 360 ALA VAL ASN GLU ASP CYS GLU LEU LYS ILE LEU ASP PHE SEQRES 14 A 360 GLY LEU ALA ARG HIS THR ASP ASP GLU MET THR GLY TYR SEQRES 15 A 360 VAL ALA GLY ARG TRP TYR ARG ALA PRO GLU ILE MET LEU SEQRES 16 A 360 ASN TRP MET HIS TYR ASN GLN THR VAL ASP ILE TRP SER SEQRES 17 A 360 VAL GLY CYS ILE MET ALA GLU LEU LEU THR GLY ARG THR SEQRES 18 A 360 LEU PHE PRO GLY THR ASP HIS ILE ASP GLN LEU LYS LEU SEQRES 19 A 360 ILE LEU ARG LEU VAL GLY THR PRO GLY ALA GLU LEU LEU SEQRES 20 A 360 LYS LYS ILE SER SER GLU SER ALA ARG ASN TYR ILE GLN SEQRES 21 A 360 SER LEU ALA GLN MET PRO LYS MET ASN PHE ALA ASN VAL SEQRES 22 A 360 PHE ILE GLY ALA ASN PRO LEU ALA VAL ASP LEU LEU GLU SEQRES 23 A 360 LYS MET LEU VAL LEU ASP SER ASP LYS ARG ILE THR ALA SEQRES 24 A 360 ALA GLN ALA LEU ALA HIS ALA TYR PHE ALA GLN TYR HIS SEQRES 25 A 360 ASP PRO ASP ASP GLU PRO VAL ALA ASP PRO TYR ASP GLN SEQRES 26 A 360 SER PHE GLU SER ARG ASP LEU LEU ILE ASP GLU TRP LYS SEQRES 27 A 360 SER LEU THR TYR ASP GLU VAL ILE SER PHE VAL PRO PRO SEQRES 28 A 360 PRO LEU ASP GLN GLU GLU MET GLU SER SEQRES 1 B 29 ARG VAL TYR PRO VAL SER VAL PRO TYR SER SER ALA GLN SEQRES 2 B 29 SER THR SER LYS THR SER VAL THR LEU SER LEU VAL MET SEQRES 3 B 29 PRO SER GLN HET SB4 A 401 25 HETNAM SB4 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4- HETNAM 2 SB4 PYRIMIDINYL)-IMIDAZOLE HETSYN SB4 SB220025 FORMUL 3 SB4 C18 H19 F N6 FORMUL 4 HOH *8(H2 O) HELIX 1 AA1 SER A 61 MET A 78 1 18 HELIX 2 AA2 SER A 95 PHE A 99 5 5 HELIX 3 AA3 LEU A 113 LYS A 118 1 6 HELIX 4 AA4 THR A 123 SER A 143 1 21 HELIX 5 AA5 LYS A 152 SER A 154 5 3 HELIX 6 AA6 VAL A 183 ARG A 189 5 7 HELIX 7 AA7 ALA A 190 LEU A 195 1 6 HELIX 8 AA8 THR A 203 GLY A 219 1 17 HELIX 9 AA9 ASP A 227 GLY A 240 1 14 HELIX 10 AB1 ASN A 269 VAL A 273 5 5 HELIX 11 AB2 ASN A 278 LEU A 289 1 12 HELIX 12 AB3 ASP A 292 ARG A 296 5 5 HELIX 13 AB4 THR A 298 HIS A 305 1 8 HELIX 14 AB5 ALA A 306 ALA A 309 5 4 HELIX 15 AB6 ASP A 313 GLU A 317 5 5 HELIX 16 AB7 GLN A 325 ARG A 330 5 6 HELIX 17 AB8 LEU A 333 SER A 347 1 15 SHEET 1 AA1 2 PHE A 8 GLU A 12 0 SHEET 2 AA1 2 ILE A 17 PRO A 21 -1 O TRP A 18 N GLN A 11 SHEET 1 AA2 5 TYR A 24 GLY A 33 0 SHEET 2 AA2 5 GLY A 36 ASP A 43 -1 O ALA A 40 N SER A 28 SHEET 3 AA2 5 ARG A 49 LEU A 55 -1 O VAL A 50 N ALA A 41 SHEET 4 AA2 5 TYR A 103 HIS A 107 -1 O LEU A 104 N LYS A 53 SHEET 5 AA2 5 ASP A 88 PHE A 90 -1 N PHE A 90 O TYR A 103 SHEET 1 AA3 3 ALA A 111 ASP A 112 0 SHEET 2 AA3 3 LEU A 156 VAL A 158 -1 O VAL A 158 N ALA A 111 SHEET 3 AA3 3 LEU A 164 ILE A 166 -1 O LYS A 165 N ALA A 157 SITE 1 AC1 11 VAL A 30 SER A 32 GLY A 33 ALA A 51 SITE 2 AC1 11 LEU A 104 VAL A 105 THR A 106 HIS A 107 SITE 3 AC1 11 LEU A 108 MET A 109 LEU A 167 CRYST1 45.920 73.580 58.970 90.00 91.09 90.00 P 1 21 1 2 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.021777 0.000000 0.000414 0.00000 SCALE2 0.000000 0.013591 0.000000 0.00000 SCALE3 0.000000 0.000000 0.016961 0.00000 ATOM 1 N ARG A 5 -24.067 -1.293 -55.430 1.00103.33 N ATOM 2 CA ARG A 5 -24.688 -0.418 -54.440 1.00108.85 C ATOM 3 C ARG A 5 -25.997 -0.993 -53.915 1.00108.17 C ATOM 4 O ARG A 5 -26.896 -1.324 -54.696 1.00111.52 O ATOM 5 CB ARG A 5 -24.942 0.972 -55.022 1.00105.90 C ATOM 6 CG ARG A 5 -25.585 1.935 -54.029 1.00 99.89 C ATOM 7 CD ARG A 5 -26.132 3.155 -54.742 1.00103.54 C ATOM 8 NE ARG A 5 -26.765 4.106 -53.836 1.00101.06 N ATOM 9 CZ ARG A 5 -28.064 4.126 -53.555 1.00101.13 C ATOM 10 NH1 ARG A 5 -28.881 3.227 -54.093 1.00101.15 N ATOM 11 NH2 ARG A 5 -28.544 5.040 -52.725 1.00 99.54 N ATOM 12 N PRO A 6 -26.095 -1.117 -52.594 1.00102.05 N ATOM 13 CA PRO A 6 -27.310 -1.666 -51.989 1.00101.65 C ATOM 14 C PRO A 6 -28.454 -0.667 -52.022 1.00100.69 C ATOM 15 O PRO A 6 -28.271 0.541 -52.189 1.00101.93 O ATOM 16 CB PRO A 6 -26.882 -1.972 -50.545 1.00 98.26 C ATOM 17 CG PRO A 6 -25.770 -1.013 -50.277 1.00 97.78 C ATOM 18 CD PRO A 6 -25.026 -0.923 -51.601 1.00105.94 C ATOM 19 N THR A 7 -29.657 -1.206 -51.857 1.00 99.94 N ATOM 20 CA THR A 7 -30.849 -0.380 -51.785 1.00 97.02 C ATOM 21 C THR A 7 -30.993 0.167 -50.379 1.00 92.51 C ATOM 22 O THR A 7 -30.857 -0.571 -49.398 1.00 92.09 O ATOM 23 CB THR A 7 -32.086 -1.183 -52.174 1.00 99.45 C ATOM 24 OG1 THR A 7 -31.958 -1.607 -53.540 1.00109.87 O ATOM 25 CG2 THR A 7 -33.343 -0.332 -52.015 1.00 99.61 C ATOM 26 N PHE A 8 -31.257 1.460 -50.283 1.00 91.98 N ATOM 27 CA PHE A 8 -31.433 2.127 -49.008 1.00 87.91 C ATOM 28 C PHE A 8 -32.911 2.272 -48.695 1.00 91.40 C ATOM 29 O PHE A 8 -33.782 2.015 -49.533 1.00 95.29 O ATOM 30 CB PHE A 8 -30.779 3.505 -49.029 1.00 86.57 C ATOM 31 CG PHE A 8 -29.295 3.473 -48.911 1.00 82.14 C ATOM 32 CD1 PHE A 8 -28.668 4.137 -47.895 1.00 78.09 C ATOM 33 CD2 PHE A 8 -28.527 2.786 -49.836 1.00 92.07 C ATOM 34 CE1 PHE A 8 -27.305 4.124 -47.782 1.00 78.46 C ATOM 35 CE2 PHE A 8 -27.154 2.767 -49.728 1.00 93.01 C ATOM 36 CZ PHE A 8 -26.545 3.441 -48.689 1.00 81.63 C ATOM 37 N TYR A 9 -33.181 2.715 -47.470 1.00 83.50 N ATOM 38 CA TYR A 9 -34.518 3.081 -47.045 1.00 88.37 C ATOM 39 C TYR A 9 -34.412 4.196 -46.014 1.00 95.52 C ATOM 40 O TYR A 9 -33.395 4.342 -45.335 1.00 98.32 O ATOM 41 CB TYR A 9 -35.277 1.875 -46.488 1.00 95.71 C ATOM 42 CG TYR A 9 -34.985 1.494 -45.054 1.00 93.10 C ATOM 43 CD1 TYR A 9 -35.764 1.996 -44.017 1.00 98.35 C ATOM 44 CD2 TYR A 9 -33.971 0.590 -44.739 1.00 91.84 C ATOM 45 CE1 TYR A 9 -35.522 1.638 -42.698 1.00 97.86 C ATOM 46 CE2 TYR A 9 -33.725 0.217 -43.423 1.00 93.27 C ATOM 47 CZ TYR A 9 -34.502 0.749 -42.410 1.00 97.97 C ATOM 48 OH TYR A 9 -34.260 0.381 -41.106 1.00 99.86 O ATOM 49 N ARG A 10 -35.469 4.997 -45.908 1.00 97.98 N ATOM 50 CA ARG A 10 -35.469 6.184 -45.063 1.00 97.22 C ATOM 51 C ARG A 10 -36.405 6.006 -43.875 1.00 98.25 C ATOM 52 O ARG A 10 -37.372 5.242 -43.934 1.00 97.45 O ATOM 53 CB ARG A 10 -35.883 7.431 -45.853 1.00 93.28 C ATOM 54 N GLN A 11 -36.113 6.731 -42.795 1.00 99.52 N ATOM 55 CA GLN A 11 -36.937 6.706 -41.595 1.00101.65 C ATOM 56 C GLN A 11 -36.450 7.793 -40.649 1.00110.83 C ATOM 57 O GLN A 11 -35.240 7.975 -40.484 1.00111.03 O ATOM 58 CB GLN A 11 -36.886 5.337 -40.909 1.00100.27 C ATOM 59 N GLU A 12 -37.394 8.506 -40.030 1.00111.81 N ATOM 60 CA GLU A 12 -37.076 9.632 -39.160 1.00109.43 C ATOM 61 C GLU A 12 -36.955 9.164 -37.721 1.00110.26 C ATOM 62 O GLU A 12 -37.745 8.337 -37.262 1.00115.35 O ATOM 63 CB GLU A 12 -38.152 10.718 -39.255 1.00112.09 C ATOM 64 N LEU A 13 -35.977 9.717 -37.007 1.00112.80 N ATOM 65 CA LEU A 13 -35.661 9.279 -35.649 1.00114.39 C ATOM 66 C LEU A 13 -35.104 10.457 -34.873 1.00116.85 C ATOM 67 O LEU A 13 -34.111 11.059 -35.297 1.00116.68 O ATOM 68 CB LEU A 13 -34.654 8.128 -35.657 1.00110.97 C ATOM 69 N ASN A 14 -35.732 10.757 -33.732 1.00118.62 N ATOM 70 CA ASN A 14 -35.479 11.994 -32.992 1.00118.91 C ATOM 71 C ASN A 14 -35.492 13.192 -33.941 1.00121.48 C ATOM 72 O ASN A 14 -34.643 14.082 -33.873 1.00125.03 O ATOM 73 CB ASN A 14 -34.171 11.915 -32.202 1.00115.66 C ATOM 74 N LYS A 15 -36.458 13.187 -34.861 1.00121.29 N ATOM 75 CA LYS A 15 -36.708 14.294 -35.780 1.00122.53 C ATOM 76 C LYS A 15 -35.555 14.527 -36.754 1.00119.35 C ATOM 77 O LYS A 15 -35.238 15.675 -37.072 1.00122.98 O ATOM 78 CB LYS A 15 -37.021 15.591 -35.020 1.00120.91 C ATOM 79 N THR A 16 -34.907 13.461 -37.223 1.00115.40 N ATOM 80 CA THR A 16 -34.045 13.549 -38.398 1.00116.90 C ATOM 81 C THR A 16 -34.130 12.257 -39.196 1.00108.40 C ATOM 82 O THR A 16 -34.458 11.194 -38.671 1.00113.11 O ATOM 83 CB THR A 16 -32.573 13.844 -38.069 1.00115.71 C ATOM 84 OG1 THR A 16 -31.776 13.618 -39.247 1.00113.29 O ATOM 85 CG2 THR A 16 -32.089 12.974 -36.911 1.00110.90 C ATOM 86 N ILE A 17 -33.818 12.361 -40.465 1.00107.29 N ATOM 87 CA ILE A 17 -34.016 11.259 -41.398 1.00108.07 C ATOM 88 C ILE A 17 -32.718 10.483 -41.553 1.00106.69 C ATOM 89 O ILE A 17 -31.628 11.063 -41.670 1.00105.51 O ATOM 90 CB ILE A 17 -34.525 11.771 -42.757 1.00104.05 C ATOM 91 N TRP A 18 -32.842 9.158 -41.562 1.00104.90 N ATOM 92 CA TRP A 18 -31.718 8.242 -41.679 1.00 95.08 C ATOM 93 C TRP A 18 -31.870 7.426 -42.955 1.00 95.83 C ATOM 94 O TRP A 18 -32.959 6.909 -43.229 1.00100.09 O ATOM 95 CB TRP A 18 -31.669 7.300 -40.479 1.00 94.26 C ATOM 96 CG TRP A 18 -31.323 7.933 -39.161 1.00 99.31 C ATOM 97 CD1 TRP A 18 -31.994 8.941 -38.520 1.00 99.68 C ATOM 98 CD2 TRP A 18 -30.237 7.566 -38.309 1.00 88.26 C ATOM 99 NE1 TRP A 18 -31.377 9.228 -37.323 1.00 99.60 N ATOM 100 CE2 TRP A 18 -30.297 8.400 -37.171 1.00 90.29 C ATOM 101 CE3 TRP A 18 -29.210 6.623 -38.405 1.00 81.90 C ATOM 102 CZ2 TRP A 18 -29.372 8.312 -36.130 1.00 89.04 C ATOM 103 CZ3 TRP A 18 -28.300 6.523 -37.365 1.00 90.07 C ATOM 104 CH2 TRP A 18 -28.386 7.368 -36.238 1.00 85.66 C ATOM 105 N GLU A 19 -30.784 7.291 -43.721 1.00 92.78 N ATOM 106 CA GLU A 19 -30.786 6.538 -44.979 1.00 94.37 C ATOM 107 C GLU A 19 -29.708 5.459 -44.891 1.00 88.20 C ATOM 108 O GLU A 19 -28.511 5.772 -44.900 1.00 87.59 O ATOM 109 CB GLU A 19 -30.558 7.460 -46.184 1.00 78.26 C ATOM 110 N VAL A 20 -30.128 4.196 -44.823 1.00 83.49 N ATOM 111 CA VAL A 20 -29.236 3.087 -44.484 1.00 80.98 C ATOM 112 C VAL A 20 -29.475 1.930 -45.441 1.00 81.57 C ATOM 113 O VAL A 20 -30.573 1.778 -45.993 1.00 85.63 O ATOM 114 CB VAL A 20 -29.456 2.607 -43.040 1.00 84.13 C ATOM 115 CG1 VAL A 20 -29.578 3.773 -42.095 1.00 86.71 C ATOM 116 CG2 VAL A 20 -30.714 1.808 -42.971 1.00 87.21 C ATOM 117 N PRO A 21 -28.463 1.084 -45.648 1.00 84.47 N ATOM 118 CA PRO A 21 -28.708 -0.152 -46.397 1.00 79.45 C ATOM 119 C PRO A 21 -29.797 -0.978 -45.735 1.00 77.30 C ATOM 120 O PRO A 21 -30.070 -0.852 -44.540 1.00 78.16 O ATOM 121 CB PRO A 21 -27.354 -0.876 -46.374 1.00 70.18 C ATOM 122 CG PRO A 21 -26.342 0.196 -46.194 1.00 80.13 C ATOM 123 CD PRO A 21 -27.032 1.269 -45.339 1.00 82.30 C ATOM 124 N GLU A 22 -30.458 -1.805 -46.549 1.00 84.34 N ATOM 125 CA GLU A 22 -31.546 -2.633 -46.039 1.00 80.25 C ATOM 126 C GLU A 22 -31.052 -3.586 -44.957 1.00 75.97 C ATOM 127 O GLU A 22 -31.807 -3.932 -44.045 1.00 72.15 O ATOM 128 CB GLU A 22 -32.195 -3.404 -47.202 1.00 77.78 C ATOM 129 N ARG A 23 -29.777 -3.978 -45.022 1.00 70.75 N ATOM 130 CA ARG A 23 -29.242 -4.953 -44.082 1.00 71.86 C ATOM 131 C ARG A 23 -29.455 -4.537 -42.617 1.00 76.67 C ATOM 132 O ARG A 23 -29.739 -5.386 -41.763 1.00 75.86 O ATOM 133 CB ARG A 23 -27.760 -5.208 -44.384 1.00 66.63 C ATOM 134 CG ARG A 23 -26.825 -4.072 -44.112 1.00 65.52 C ATOM 135 CD ARG A 23 -25.425 -4.410 -44.557 1.00 58.73 C ATOM 136 NE ARG A 23 -24.783 -5.425 -43.731 1.00 58.53 N ATOM 137 CZ ARG A 23 -23.480 -5.699 -43.781 1.00 66.50 C ATOM 138 NH1 ARG A 23 -22.700 -5.017 -44.614 1.00 63.47 N ATOM 139 NH2 ARG A 23 -22.945 -6.640 -43.006 1.00 61.10 N ATOM 140 N TYR A 24 -29.341 -3.254 -42.288 1.00 73.21 N ATOM 141 CA TYR A 24 -29.508 -2.855 -40.888 1.00 74.02 C ATOM 142 C TYR A 24 -30.991 -2.592 -40.622 1.00 78.96 C ATOM 143 O TYR A 24 -31.628 -1.812 -41.342 1.00 83.79 O ATOM 144 CB TYR A 24 -28.640 -1.638 -40.553 1.00 67.75 C ATOM 145 CG TYR A 24 -27.190 -1.812 -40.942 1.00 62.43 C ATOM 146 CD1 TYR A 24 -26.677 -1.148 -42.031 1.00 71.12 C ATOM 147 CD2 TYR A 24 -26.336 -2.611 -40.217 1.00 68.66 C ATOM 148 CE1 TYR A 24 -25.369 -1.296 -42.415 1.00 62.90 C ATOM 149 CE2 TYR A 24 -25.001 -2.759 -40.604 1.00 66.62 C ATOM 150 CZ TYR A 24 -24.542 -2.093 -41.715 1.00 58.18 C ATOM 151 OH TYR A 24 -23.242 -2.201 -42.122 1.00 61.70 O ATOM 152 N GLN A 25 -31.540 -3.245 -39.592 1.00 83.68 N ATOM 153 CA GLN A 25 -32.984 -3.302 -39.368 1.00 85.10 C ATOM 154 C GLN A 25 -33.333 -3.043 -37.902 1.00 85.22 C ATOM 155 O GLN A 25 -32.530 -3.276 -36.984 1.00 86.39 O ATOM 156 CB GLN A 25 -33.572 -4.667 -39.791 1.00 83.31 C ATOM 157 CG GLN A 25 -33.503 -4.975 -41.291 1.00 83.13 C ATOM 158 CD GLN A 25 -34.453 -4.099 -42.097 1.00 90.31 C ATOM 159 OE1 GLN A 25 -35.552 -3.767 -41.638 1.00 89.98 O ATOM 160 NE2 GLN A 25 -34.024 -3.700 -43.295 1.00 84.61 N ATOM 161 N ASN A 26 -34.574 -2.597 -37.685 1.00 87.46 N ATOM 162 CA ASN A 26 -35.078 -2.275 -36.349 1.00 83.24 C ATOM 163 C ASN A 26 -34.213 -1.205 -35.675 1.00 87.22 C ATOM 164 O ASN A 26 -33.824 -1.338 -34.510 1.00 96.05 O ATOM 165 CB ASN A 26 -35.180 -3.534 -35.473 1.00 84.49 C ATOM 166 CG ASN A 26 -35.882 -4.711 -36.191 1.00102.47 C ATOM 167 OD1 ASN A 26 -37.083 -4.642 -36.495 1.00102.98 O ATOM 168 ND2 ASN A 26 -35.133 -5.791 -36.454 1.00 92.58 N ATOM 169 N LEU A 27 -33.901 -0.135 -36.413 1.00 77.41 N ATOM 170 CA LEU A 27 -33.018 0.894 -35.864 1.00 86.96 C ATOM 171 C LEU A 27 -33.670 1.575 -34.658 1.00 93.03 C ATOM 172 O LEU A 27 -34.854 1.928 -34.700 1.00 95.48 O ATOM 173 CB LEU A 27 -32.669 1.936 -36.927 1.00 81.97 C ATOM 174 CG LEU A 27 -31.535 1.505 -37.871 1.00 87.16 C ATOM 175 N SER A 28 -32.895 1.748 -33.579 1.00 82.98 N ATOM 176 CA SER A 28 -33.379 2.292 -32.317 1.00 83.40 C ATOM 177 C SER A 28 -32.338 3.203 -31.670 1.00 86.58 C ATOM 178 O SER A 28 -31.202 2.767 -31.421 1.00 85.07 O ATOM 179 CB SER A 28 -33.749 1.143 -31.364 1.00 90.08 C ATOM 180 OG SER A 28 -34.361 1.602 -30.172 1.00 89.96 O ATOM 181 N PRO A 29 -32.685 4.465 -31.384 1.00 90.54 N ATOM 182 CA PRO A 29 -31.720 5.387 -30.758 1.00 89.88 C ATOM 183 C PRO A 29 -31.228 4.891 -29.408 1.00 81.03 C ATOM 184 O PRO A 29 -31.975 4.259 -28.657 1.00 86.29 O ATOM 185 CB PRO A 29 -32.523 6.687 -30.610 1.00 93.72 C ATOM 186 CG PRO A 29 -33.537 6.619 -31.737 1.00 92.24 C ATOM 187 CD PRO A 29 -33.914 5.155 -31.806 1.00 95.43 C ATOM 188 N VAL A 30 -29.953 5.180 -29.102 1.00 81.75 N ATOM 189 CA VAL A 30 -29.371 4.796 -27.813 1.00 81.77 C ATOM 190 C VAL A 30 -28.589 5.958 -27.198 1.00 81.97 C ATOM 191 O VAL A 30 -27.800 5.756 -26.252 1.00 87.41 O ATOM 192 CB VAL A 30 -28.456 3.559 -27.924 1.00 71.03 C ATOM 193 N GLY A 31 -28.793 7.178 -27.707 1.00 86.97 N ATOM 194 CA GLY A 31 -28.228 8.343 -27.067 1.00 83.10 C ATOM 195 C GLY A 31 -27.291 9.095 -28.005 1.00 83.17 C ATOM 196 O GLY A 31 -27.442 9.042 -29.236 1.00 84.14 O ATOM 197 N SER A 32 -26.328 9.796 -27.397 1.00 86.23 N ATOM 198 CA SER A 32 -25.432 10.677 -28.116 1.00 83.73 C ATOM 199 C SER A 32 -24.053 10.049 -28.261 1.00 76.86 C ATOM 200 O SER A 32 -23.617 9.276 -27.406 1.00 77.74 O ATOM 201 CB SER A 32 -25.306 12.018 -27.403 1.00 82.84 C ATOM 202 OG SER A 32 -26.573 12.630 -27.229 1.00 96.51 O ATOM 203 N GLY A 33 -23.363 10.413 -29.339 1.00 81.15 N ATOM 204 CA GLY A 33 -21.952 10.132 -29.479 1.00 78.18 C ATOM 205 C GLY A 33 -21.233 11.346 -30.035 1.00 83.78 C ATOM 206 O GLY A 33 -21.797 12.449 -30.051 1.00 88.45 O ATOM 207 N ALA A 34 -19.996 11.177 -30.502 1.00 71.83 N ATOM 208 CA ALA A 34 -19.170 12.350 -30.752 1.00 70.75 C ATOM 209 C ALA A 34 -19.585 12.990 -32.070 1.00 79.32 C ATOM 210 O ALA A 34 -19.428 12.394 -33.148 1.00 82.32 O ATOM 211 CB ALA A 34 -17.694 11.977 -30.754 1.00 72.53 C ATOM 212 N TYR A 35 -20.134 14.202 -31.978 1.00 76.84 N ATOM 213 CA TYR A 35 -20.574 14.991 -33.137 1.00 80.63 C ATOM 214 C TYR A 35 -21.712 14.314 -33.908 1.00 85.03 C ATOM 215 O TYR A 35 -21.833 14.488 -35.132 1.00 87.20 O ATOM 216 CB TYR A 35 -19.425 15.295 -34.110 1.00 80.70 C ATOM 217 CG TYR A 35 -18.060 15.620 -33.556 1.00 84.01 C ATOM 218 CD1 TYR A 35 -17.821 16.807 -32.863 1.00 90.57 C ATOM 219 CD2 TYR A 35 -16.982 14.788 -33.808 1.00 81.55 C ATOM 220 CE1 TYR A 35 -16.545 17.122 -32.397 1.00 89.92 C ATOM 221 CE2 TYR A 35 -15.716 15.086 -33.342 1.00 84.36 C ATOM 222 CZ TYR A 35 -15.496 16.253 -32.644 1.00 85.95 C ATOM 223 OH TYR A 35 -14.214 16.520 -32.207 1.00 86.70 O ATOM 224 N GLY A 36 -22.548 13.553 -33.207 1.00 81.30 N ATOM 225 CA GLY A 36 -23.697 12.926 -33.843 1.00 76.74 C ATOM 226 C GLY A 36 -24.532 12.175 -32.822 1.00 86.10 C ATOM 227 O GLY A 36 -24.349 12.323 -31.602 1.00 76.07 O ATOM 228 N SER A 37 -25.459 11.352 -33.340 1.00 76.92 N ATOM 229 CA SER A 37 -26.232 10.434 -32.502 1.00 87.10 C ATOM 230 C SER A 37 -26.231 9.035 -33.104 1.00 79.95 C ATOM 231 O SER A 37 -25.992 8.855 -34.300 1.00 87.24 O ATOM 232 CB SER A 37 -27.668 10.936 -32.246 1.00 88.97 C ATOM 233 OG SER A 37 -27.686 12.307 -31.874 1.00 93.33 O ATOM 234 N VAL A 38 -26.472 8.037 -32.258 1.00 71.84 N ATOM 235 CA VAL A 38 -26.206 6.660 -32.650 1.00 77.18 C ATOM 236 C VAL A 38 -27.453 5.806 -32.427 1.00 78.87 C ATOM 237 O VAL A 38 -28.196 6.002 -31.458 1.00 79.60 O ATOM 238 CB VAL A 38 -24.990 6.071 -31.878 1.00 74.32 C ATOM 239 CG1 VAL A 38 -23.814 7.056 -31.788 1.00 69.38 C ATOM 240 CG2 VAL A 38 -25.409 5.664 -30.516 1.00 79.93 C ATOM 241 N CYS A 39 -27.681 4.835 -33.315 1.00 71.99 N ATOM 242 CA CYS A 39 -28.755 3.863 -33.103 1.00 77.30 C ATOM 243 C CYS A 39 -28.205 2.452 -32.917 1.00 73.28 C ATOM 244 O CYS A 39 -27.161 2.099 -33.483 1.00 71.61 O ATOM 245 CB CYS A 39 -29.744 3.860 -34.256 1.00 79.75 C ATOM 246 SG CYS A 39 -30.657 5.419 -34.434 1.00 92.90 S ATOM 247 N ALA A 40 -28.891 1.657 -32.092 1.00 72.13 N ATOM 248 CA ALA A 40 -28.700 0.212 -32.108 1.00 67.15 C ATOM 249 C ALA A 40 -29.505 -0.384 -33.243 1.00 73.95 C ATOM 250 O ALA A 40 -30.692 -0.085 -33.396 1.00 74.78 O ATOM 251 CB ALA A 40 -29.149 -0.436 -30.801 1.00 76.61 C ATOM 252 N ALA A 41 -28.863 -1.238 -34.038 1.00 71.22 N ATOM 253 CA ALA A 41 -29.557 -1.873 -35.146 1.00 72.64 C ATOM 254 C ALA A 41 -29.187 -3.343 -35.230 1.00 67.43 C ATOM 255 O ALA A 41 -28.146 -3.781 -34.730 1.00 66.83 O ATOM 256 CB ALA A 41 -29.235 -1.173 -36.473 1.00 74.62 C ATOM 257 N PHE A 42 -30.053 -4.101 -35.901 1.00 78.48 N ATOM 258 CA PHE A 42 -29.811 -5.508 -36.213 1.00 73.61 C ATOM 259 C PHE A 42 -29.309 -5.621 -37.641 1.00 71.25 C ATOM 260 O PHE A 42 -29.966 -5.131 -38.563 1.00 74.49 O ATOM 261 CB PHE A 42 -31.081 -6.340 -36.020 1.00 72.51 C ATOM 262 CG PHE A 42 -30.856 -7.815 -36.116 1.00 74.31 C ATOM 263 CD1 PHE A 42 -30.778 -8.453 -37.358 1.00 73.08 C ATOM 264 CD2 PHE A 42 -30.693 -8.569 -34.971 1.00 75.34 C ATOM 265 CE1 PHE A 42 -30.566 -9.828 -37.436 1.00 78.07 C ATOM 266 CE2 PHE A 42 -30.479 -9.927 -35.041 1.00 74.94 C ATOM 267 CZ PHE A 42 -30.416 -10.558 -36.279 1.00 76.81 C ATOM 268 N ASP A 43 -28.170 -6.297 -37.824 1.00 66.30 N ATOM 269 CA ASP A 43 -27.553 -6.436 -39.146 1.00 77.87 C ATOM 270 C ASP A 43 -27.986 -7.754 -39.802 1.00 79.10 C ATOM 271 O ASP A 43 -27.450 -8.826 -39.492 1.00 79.31 O ATOM 272 CB ASP A 43 -26.032 -6.357 -39.038 1.00 75.56 C ATOM 273 CG ASP A 43 -25.359 -6.449 -40.402 1.00 74.99 C ATOM 274 OD1 ASP A 43 -26.098 -6.356 -41.403 1.00 75.02 O ATOM 275 OD2 ASP A 43 -24.118 -6.600 -40.480 1.00 75.96 O ATOM 276 N THR A 44 -28.933 -7.686 -40.745 1.00 75.05 N ATOM 277 CA THR A 44 -29.461 -8.931 -41.295 1.00 71.94 C ATOM 278 C THR A 44 -28.471 -9.641 -42.199 1.00 76.66 C ATOM 279 O THR A 44 -28.694 -10.806 -42.538 1.00 80.36 O ATOM 280 CB THR A 44 -30.783 -8.706 -42.028 1.00 74.90 C ATOM 281 OG1 THR A 44 -30.588 -7.870 -43.189 1.00 75.85 O ATOM 282 CG2 THR A 44 -31.807 -8.117 -41.092 1.00 75.89 C ATOM 283 N LYS A 45 -27.380 -8.987 -42.588 1.00 80.71 N ATOM 284 CA LYS A 45 -26.337 -9.726 -43.293 1.00 80.63 C ATOM 285 C LYS A 45 -25.540 -10.618 -42.343 1.00 79.45 C ATOM 286 O LYS A 45 -25.175 -11.741 -42.703 1.00 77.34 O ATOM 287 CB LYS A 45 -25.405 -8.767 -44.030 1.00 70.29 C ATOM 288 CG LYS A 45 -24.295 -9.450 -44.785 1.00 66.33 C ATOM 289 N THR A 46 -25.244 -10.153 -41.131 1.00 76.68 N ATOM 290 CA THR A 46 -24.371 -10.942 -40.286 1.00 78.39 C ATOM 291 C THR A 46 -25.066 -11.581 -39.098 1.00 78.69 C ATOM 292 O THR A 46 -24.501 -12.511 -38.515 1.00 73.37 O ATOM 293 CB THR A 46 -23.202 -10.098 -39.762 1.00 80.34 C ATOM 294 OG1 THR A 46 -23.713 -8.998 -38.998 1.00 80.72 O ATOM 295 CG2 THR A 46 -22.339 -9.587 -40.917 1.00 77.44 C ATOM 296 N GLY A 47 -26.255 -11.105 -38.718 1.00 78.23 N ATOM 297 CA GLY A 47 -26.917 -11.556 -37.505 1.00 77.58 C ATOM 298 C GLY A 47 -26.516 -10.857 -36.205 1.00 80.58 C ATOM 299 O GLY A 47 -27.053 -11.202 -35.146 1.00 76.08 O ATOM 300 N HIS A 48 -25.607 -9.886 -36.232 1.00 79.38 N ATOM 301 CA HIS A 48 -25.167 -9.225 -35.011 1.00 76.00 C ATOM 302 C HIS A 48 -25.902 -7.911 -34.784 1.00 67.73 C ATOM 303 O HIS A 48 -26.362 -7.256 -35.717 1.00 77.78 O ATOM 304 CB HIS A 48 -23.669 -8.962 -35.041 1.00 75.38 C ATOM 305 CG HIS A 48 -22.863 -10.194 -35.283 1.00 80.75 C ATOM 306 ND1 HIS A 48 -21.769 -10.217 -36.124 1.00 84.84 N ATOM 307 CD2 HIS A 48 -23.006 -11.453 -34.811 1.00 86.91 C ATOM 308 CE1 HIS A 48 -21.267 -11.439 -36.150 1.00 90.79 C ATOM 309 NE2 HIS A 48 -22.003 -12.209 -35.369 1.00 89.13 N ATOM 310 N ARG A 49 -26.017 -7.537 -33.524 1.00 73.06 N ATOM 311 CA ARG A 49 -26.480 -6.205 -33.175 1.00 73.10 C ATOM 312 C ARG A 49 -25.346 -5.209 -33.426 1.00 69.81 C ATOM 313 O ARG A 49 -24.187 -5.452 -33.058 1.00 66.18 O ATOM 314 CB ARG A 49 -26.936 -6.190 -31.712 1.00 72.03 C ATOM 315 CG ARG A 49 -28.458 -6.045 -31.516 1.00 75.90 C ATOM 316 N VAL A 50 -25.663 -4.102 -34.084 1.00 65.65 N ATOM 317 CA VAL A 50 -24.659 -3.078 -34.332 1.00 68.97 C ATOM 318 C VAL A 50 -25.145 -1.729 -33.815 1.00 70.02 C ATOM 319 O VAL A 50 -26.348 -1.466 -33.712 1.00 69.16 O ATOM 320 CB VAL A 50 -24.322 -2.955 -35.836 1.00 71.75 C ATOM 321 CG1 VAL A 50 -23.766 -4.287 -36.396 1.00 64.65 C ATOM 322 CG2 VAL A 50 -25.554 -2.481 -36.585 1.00 69.84 C ATOM 323 N ALA A 51 -24.181 -0.864 -33.500 1.00 66.57 N ATOM 324 CA ALA A 51 -24.431 0.548 -33.223 1.00 62.98 C ATOM 325 C ALA A 51 -24.075 1.347 -34.460 1.00 61.68 C ATOM 326 O ALA A 51 -22.990 1.156 -35.022 1.00 61.57 O ATOM 327 CB ALA A 51 -23.604 1.042 -32.038 1.00 61.13 C ATOM 328 N VAL A 52 -24.998 2.205 -34.898 1.00 65.31 N ATOM 329 CA VAL A 52 -24.814 3.090 -36.053 1.00 68.55 C ATOM 330 C VAL A 52 -24.815 4.538 -35.567 1.00 70.00 C ATOM 331 O VAL A 52 -25.781 4.976 -34.933 1.00 68.91 O ATOM 332 CB VAL A 52 -25.915 2.892 -37.109 1.00 60.83 C ATOM 333 CG1 VAL A 52 -25.664 3.803 -38.289 1.00 68.15 C ATOM 334 CG2 VAL A 52 -25.928 1.478 -37.593 1.00 65.42 C ATOM 335 N LYS A 53 -23.744 5.279 -35.865 1.00 71.02 N ATOM 336 CA LYS A 53 -23.647 6.722 -35.629 1.00 70.93 C ATOM 337 C LYS A 53 -23.775 7.478 -36.938 1.00 72.66 C ATOM 338 O LYS A 53 -23.063 7.169 -37.903 1.00 66.27 O ATOM 339 CB LYS A 53 -22.310 7.092 -35.003 1.00 72.95 C ATOM 340 CG LYS A 53 -22.112 8.582 -34.784 1.00 70.06 C ATOM 341 CD LYS A 53 -20.646 8.882 -34.721 1.00 68.38 C ATOM 342 CE LYS A 53 -20.194 9.217 -33.331 1.00 68.67 C ATOM 343 NZ LYS A 53 -18.750 9.516 -33.441 1.00 66.08 N ATOM 344 N LYS A 54 -24.689 8.458 -36.983 1.00 80.28 N ATOM 345 CA LYS A 54 -24.759 9.416 -38.096 1.00 83.12 C ATOM 346 C LYS A 54 -24.196 10.742 -37.601 1.00 78.13 C ATOM 347 O LYS A 54 -24.696 11.295 -36.618 1.00 74.71 O ATOM 348 CB LYS A 54 -26.188 9.614 -38.613 1.00 81.94 C ATOM 349 N LEU A 55 -23.148 11.230 -38.260 1.00 73.92 N ATOM 350 CA LEU A 55 -22.498 12.452 -37.801 1.00 84.34 C ATOM 351 C LEU A 55 -23.283 13.706 -38.201 1.00 82.64 C ATOM 352 O LEU A 55 -24.027 13.719 -39.183 1.00 79.54 O ATOM 353 CB LEU A 55 -21.064 12.525 -38.300 1.00 80.40 C ATOM 354 CG LEU A 55 -20.188 11.427 -37.695 1.00 78.55 C ATOM 355 CD1 LEU A 55 -19.108 11.020 -38.644 1.00 76.78 C ATOM 356 CD2 LEU A 55 -19.596 11.858 -36.370 1.00 75.05 C ATOM 357 N SER A 56 -23.124 14.766 -37.403 1.00 85.48 N ATOM 358 CA SER A 56 -23.878 16.011 -37.588 1.00 91.84 C ATOM 359 C SER A 56 -23.132 16.993 -38.485 1.00 85.93 C ATOM 360 O SER A 56 -21.999 17.381 -38.184 1.00 88.47 O ATOM 361 CB SER A 56 -24.174 16.648 -36.239 1.00 77.36 C ATOM 362 OG SER A 56 -25.201 15.907 -35.623 1.00 93.54 O ATOM 363 N ARG A 57 -23.790 17.407 -39.564 1.00 88.38 N ATOM 364 CA ARG A 57 -23.309 18.427 -40.494 1.00 90.93 C ATOM 365 C ARG A 57 -21.809 18.231 -40.783 1.00 89.80 C ATOM 366 O ARG A 57 -21.017 19.149 -40.580 1.00 90.72 O ATOM 367 CB ARG A 57 -23.592 19.829 -39.965 1.00 90.39 C ATOM 368 N PRO A 58 -21.418 17.048 -41.261 1.00 99.20 N ATOM 369 CA PRO A 58 -19.981 16.724 -41.348 1.00 94.36 C ATOM 370 C PRO A 58 -19.154 17.718 -42.133 1.00 94.35 C ATOM 371 O PRO A 58 -17.955 17.832 -41.864 1.00 92.64 O ATOM 372 CB PRO A 58 -19.982 15.347 -42.030 1.00 89.19 C ATOM 373 CG PRO A 58 -21.284 15.258 -42.723 1.00 89.53 C ATOM 374 CD PRO A 58 -22.250 15.990 -41.858 1.00 95.54 C ATOM 375 N PHE A 59 -19.747 18.445 -43.088 1.00 97.86 N ATOM 376 CA PHE A 59 -18.986 19.321 -43.972 1.00 96.26 C ATOM 377 C PHE A 59 -19.578 20.731 -44.001 1.00101.49 C ATOM 378 O PHE A 59 -19.372 21.490 -44.954 1.00 98.31 O ATOM 379 CB PHE A 59 -18.897 18.706 -45.372 1.00101.43 C ATOM 380 CG PHE A 59 -18.494 17.251 -45.359 1.00 96.22 C ATOM 381 CD1 PHE A 59 -17.189 16.891 -45.063 1.00 96.75 C ATOM 382 CD2 PHE A 59 -19.418 16.252 -45.602 1.00 94.91 C ATOM 383 CE1 PHE A 59 -16.809 15.558 -45.026 1.00 94.21 C ATOM 384 CE2 PHE A 59 -19.044 14.909 -45.574 1.00 96.04 C ATOM 385 CZ PHE A 59 -17.738 14.563 -45.282 1.00 92.53 C ATOM 386 N GLN A 60 -20.310 21.089 -42.944 1.00 99.80 N ATOM 387 CA GLN A 60 -20.782 22.444 -42.687 1.00100.03 C ATOM 388 C GLN A 60 -19.590 23.320 -42.296 1.00104.07 C ATOM 389 O GLN A 60 -19.003 24.000 -43.152 1.00 96.94 O ATOM 390 CB GLN A 60 -21.878 22.395 -41.599 1.00 91.62 C ATOM 391 CG GLN A 60 -22.180 23.652 -40.798 1.00 93.42 C ATOM 392 CD GLN A 60 -22.755 23.337 -39.429 1.00 92.01 C ATOM 393 N SER A 61 -19.186 23.252 -41.025 1.00 99.21 N ATOM 394 CA SER A 61 -18.104 24.076 -40.511 1.00102.96 C ATOM 395 C SER A 61 -16.748 23.595 -41.026 1.00 99.77 C ATOM 396 O SER A 61 -16.612 22.504 -41.580 1.00106.57 O ATOM 397 CB SER A 61 -18.116 24.059 -38.984 1.00102.81 C ATOM 398 OG SER A 61 -17.062 24.852 -38.489 1.00109.14 O ATOM 399 N ILE A 62 -15.731 24.436 -40.850 1.00 97.53 N ATOM 400 CA ILE A 62 -14.387 24.036 -41.248 1.00 99.62 C ATOM 401 C ILE A 62 -13.868 22.966 -40.305 1.00103.06 C ATOM 402 O ILE A 62 -13.371 21.915 -40.739 1.00104.15 O ATOM 403 CB ILE A 62 -13.444 25.250 -41.297 1.00105.24 C ATOM 404 N ILE A 63 -13.989 23.214 -38.995 1.00 98.34 N ATOM 405 CA ILE A 63 -13.674 22.171 -38.026 1.00100.92 C ATOM 406 C ILE A 63 -14.409 20.900 -38.399 1.00 98.68 C ATOM 407 O ILE A 63 -13.821 19.813 -38.427 1.00 97.74 O ATOM 408 CB ILE A 63 -14.014 22.606 -36.583 1.00 90.92 C ATOM 409 CG1 ILE A 63 -15.245 23.507 -36.536 1.00 94.39 C ATOM 410 CG2 ILE A 63 -12.828 23.281 -35.956 1.00 93.66 C ATOM 411 N HIS A 64 -15.689 21.026 -38.756 1.00 94.74 N ATOM 412 CA HIS A 64 -16.500 19.839 -38.968 1.00 97.06 C ATOM 413 C HIS A 64 -15.892 18.948 -40.038 1.00 90.17 C ATOM 414 O HIS A 64 -15.675 17.761 -39.802 1.00 87.04 O ATOM 415 CB HIS A 64 -17.934 20.230 -39.300 1.00 98.08 C ATOM 416 CG HIS A 64 -18.723 20.600 -38.087 1.00 98.68 C ATOM 417 ND1 HIS A 64 -19.996 21.126 -38.149 1.00 95.68 N ATOM 418 CD2 HIS A 64 -18.406 20.524 -36.772 1.00 96.85 C ATOM 419 CE1 HIS A 64 -20.430 21.354 -36.924 1.00104.80 C ATOM 420 NE2 HIS A 64 -19.485 20.998 -36.070 1.00105.74 N ATOM 421 N ALA A 65 -15.556 19.505 -41.204 1.00 96.89 N ATOM 422 CA ALA A 65 -14.875 18.687 -42.211 1.00 90.48 C ATOM 423 C ALA A 65 -13.601 18.077 -41.638 1.00 93.73 C ATOM 424 O ALA A 65 -13.323 16.883 -41.830 1.00 83.41 O ATOM 425 CB ALA A 65 -14.572 19.507 -43.457 1.00 90.75 C ATOM 426 N LYS A 66 -12.827 18.875 -40.901 1.00 95.59 N ATOM 427 CA LYS A 66 -11.638 18.341 -40.255 1.00 91.63 C ATOM 428 C LYS A 66 -12.015 17.321 -39.188 1.00 84.75 C ATOM 429 O LYS A 66 -11.400 16.258 -39.092 1.00 76.08 O ATOM 430 CB LYS A 66 -10.808 19.478 -39.653 1.00 87.79 C ATOM 431 N ARG A 67 -13.016 17.638 -38.368 1.00 83.84 N ATOM 432 CA ARG A 67 -13.437 16.699 -37.339 1.00 80.63 C ATOM 433 C ARG A 67 -13.985 15.426 -37.975 1.00 80.22 C ATOM 434 O ARG A 67 -13.759 14.318 -37.476 1.00 76.90 O ATOM 435 CB ARG A 67 -14.473 17.349 -36.419 1.00 79.36 C ATOM 436 N THR A 68 -14.656 15.559 -39.111 1.00 78.41 N ATOM 437 CA THR A 68 -15.248 14.394 -39.743 1.00 77.00 C ATOM 438 C THR A 68 -14.185 13.527 -40.412 1.00 76.92 C ATOM 439 O THR A 68 -14.207 12.293 -40.288 1.00 67.77 O ATOM 440 CB THR A 68 -16.333 14.847 -40.712 1.00 76.49 C ATOM 441 OG1 THR A 68 -17.508 15.159 -39.959 1.00 80.01 O ATOM 442 CG2 THR A 68 -16.649 13.768 -41.731 1.00 83.99 C ATOM 443 N TYR A 69 -13.219 14.154 -41.077 1.00 73.51 N ATOM 444 CA TYR A 69 -12.124 13.385 -41.655 1.00 72.83 C ATOM 445 C TYR A 69 -11.345 12.663 -40.563 1.00 65.60 C ATOM 446 O TYR A 69 -10.937 11.502 -40.730 1.00 62.77 O ATOM 447 CB TYR A 69 -11.203 14.311 -42.475 1.00 77.21 C ATOM 448 CG TYR A 69 -10.091 13.580 -43.195 1.00 69.04 C ATOM 449 CD1 TYR A 69 -10.380 12.629 -44.130 1.00 73.65 C ATOM 450 CD2 TYR A 69 -8.753 13.836 -42.907 1.00 74.96 C ATOM 451 CE1 TYR A 69 -9.378 11.931 -44.790 1.00 79.75 C ATOM 452 CE2 TYR A 69 -7.732 13.138 -43.555 1.00 72.26 C ATOM 453 CZ TYR A 69 -8.057 12.187 -44.504 1.00 81.04 C ATOM 454 OH TYR A 69 -7.091 11.455 -45.188 1.00 84.84 O ATOM 455 N ARG A 70 -11.163 13.339 -39.431 1.00 66.51 N ATOM 456 CA ARG A 70 -10.297 12.863 -38.363 1.00 62.10 C ATOM 457 C ARG A 70 -10.846 11.584 -37.743 1.00 62.02 C ATOM 458 O ARG A 70 -10.116 10.606 -37.566 1.00 56.07 O ATOM 459 CB ARG A 70 -10.146 13.958 -37.294 1.00 62.65 C ATOM 460 CG ARG A 70 -9.264 13.567 -36.102 1.00 66.77 C ATOM 461 CD ARG A 70 -9.153 14.673 -35.039 1.00 73.75 C ATOM 462 NE ARG A 70 -8.359 15.782 -35.540 1.00 71.42 N ATOM 463 CZ ARG A 70 -8.854 16.984 -35.782 1.00 81.37 C ATOM 464 NH1 ARG A 70 -8.068 17.941 -36.264 1.00 79.94 N ATOM 465 NH2 ARG A 70 -10.138 17.222 -35.554 1.00 82.65 N ATOM 466 N GLU A 71 -12.126 11.596 -37.371 1.00 57.83 N ATOM 467 CA GLU A 71 -12.741 10.417 -36.791 1.00 60.77 C ATOM 468 C GLU A 71 -12.646 9.238 -37.747 1.00 60.05 C ATOM 469 O GLU A 71 -12.112 8.175 -37.388 1.00 53.71 O ATOM 470 CB GLU A 71 -14.194 10.708 -36.414 1.00 64.25 C ATOM 471 CG GLU A 71 -14.932 9.522 -35.762 1.00 63.86 C ATOM 472 CD GLU A 71 -16.235 9.974 -35.156 1.00 65.44 C ATOM 473 OE1 GLU A 71 -16.642 11.095 -35.502 1.00 71.36 O ATOM 474 OE2 GLU A 71 -16.849 9.239 -34.344 1.00 71.56 O ATOM 475 N LEU A 72 -13.103 9.428 -38.996 1.00 60.61 N ATOM 476 CA LEU A 72 -13.066 8.313 -39.941 1.00 57.13 C ATOM 477 C LEU A 72 -11.640 7.840 -40.179 1.00 56.07 C ATOM 478 O LEU A 72 -11.412 6.637 -40.324 1.00 61.79 O ATOM 479 CB LEU A 72 -13.751 8.671 -41.273 1.00 51.60 C ATOM 480 CG LEU A 72 -13.821 7.512 -42.286 1.00 66.62 C ATOM 481 CD1 LEU A 72 -14.459 6.244 -41.665 1.00 48.98 C ATOM 482 CD2 LEU A 72 -14.515 7.900 -43.705 1.00 61.98 C ATOM 483 N ARG A 73 -10.656 8.727 -40.137 1.00 53.12 N ATOM 484 CA ARG A 73 -9.288 8.236 -40.238 1.00 58.32 C ATOM 485 C ARG A 73 -8.942 7.336 -39.039 1.00 64.45 C ATOM 486 O ARG A 73 -8.445 6.215 -39.212 1.00 60.77 O ATOM 487 CB ARG A 73 -8.326 9.421 -40.337 1.00 68.24 C ATOM 488 CG ARG A 73 -8.180 10.081 -41.711 1.00 72.82 C ATOM 489 CD ARG A 73 -7.725 9.128 -42.816 1.00 71.18 C ATOM 490 NE ARG A 73 -6.394 8.562 -42.611 1.00 70.41 N ATOM 491 CZ ARG A 73 -5.248 9.223 -42.745 1.00 76.45 C ATOM 492 NH1 ARG A 73 -4.095 8.602 -42.552 1.00 84.64 N ATOM 493 NH2 ARG A 73 -5.251 10.514 -43.038 1.00 87.04 N ATOM 494 N LEU A 74 -9.221 7.811 -37.808 1.00 58.39 N ATOM 495 CA LEU A 74 -8.901 7.036 -36.612 1.00 62.33 C ATOM 496 C LEU A 74 -9.672 5.726 -36.596 1.00 63.44 C ATOM 497 O LEU A 74 -9.120 4.674 -36.258 1.00 60.83 O ATOM 498 CB LEU A 74 -9.224 7.845 -35.353 1.00 60.23 C ATOM 499 CG LEU A 74 -8.262 8.974 -35.026 1.00 68.58 C ATOM 500 CD1 LEU A 74 -8.896 9.954 -34.032 1.00 63.43 C ATOM 501 CD2 LEU A 74 -6.914 8.445 -34.540 1.00 67.22 C ATOM 502 N LEU A 75 -10.956 5.777 -36.947 1.00 56.60 N ATOM 503 CA LEU A 75 -11.756 4.574 -36.846 1.00 62.17 C ATOM 504 C LEU A 75 -11.350 3.554 -37.894 1.00 60.08 C ATOM 505 O LEU A 75 -11.445 2.351 -37.638 1.00 64.15 O ATOM 506 CB LEU A 75 -13.238 4.909 -36.950 1.00 59.16 C ATOM 507 CG LEU A 75 -13.853 5.648 -35.754 1.00 62.76 C ATOM 508 CD1 LEU A 75 -15.345 5.852 -35.994 1.00 60.59 C ATOM 509 CD2 LEU A 75 -13.562 4.974 -34.345 1.00 63.05 C ATOM 510 N LYS A 76 -10.832 3.997 -39.037 1.00 61.31 N ATOM 511 CA LYS A 76 -10.392 3.016 -40.024 1.00 65.07 C ATOM 512 C LYS A 76 -9.077 2.379 -39.612 1.00 61.05 C ATOM 513 O LYS A 76 -8.754 1.271 -40.057 1.00 60.66 O ATOM 514 CB LYS A 76 -10.251 3.668 -41.416 1.00 62.32 C ATOM 515 CG LYS A 76 -11.564 4.050 -42.066 1.00 63.35 C ATOM 516 CD LYS A 76 -11.338 4.629 -43.486 1.00 73.32 C ATOM 517 CE LYS A 76 -10.780 3.553 -44.460 1.00 74.02 C ATOM 518 NZ LYS A 76 -10.399 3.994 -45.801 1.00 60.11 N ATOM 519 N HIS A 77 -8.314 3.049 -38.766 1.00 66.71 N ATOM 520 CA HIS A 77 -7.031 2.491 -38.378 1.00 65.30 C ATOM 521 C HIS A 77 -7.108 1.594 -37.146 1.00 69.10 C ATOM 522 O HIS A 77 -6.245 0.730 -36.982 1.00 71.49 O ATOM 523 CB HIS A 77 -6.016 3.617 -38.144 1.00 66.31 C ATOM 524 CG HIS A 77 -4.610 3.130 -37.976 1.00 75.19 C ATOM 525 ND1 HIS A 77 -3.856 2.650 -39.032 1.00 78.26 N ATOM 526 CD2 HIS A 77 -3.811 3.070 -36.882 1.00 72.11 C ATOM 527 CE1 HIS A 77 -2.657 2.309 -38.591 1.00 80.81 C ATOM 528 NE2 HIS A 77 -2.604 2.557 -37.290 1.00 81.64 N ATOM 529 N MET A 78 -8.105 1.760 -36.276 1.00 68.35 N ATOM 530 CA MET A 78 -8.088 1.083 -34.979 1.00 64.19 C ATOM 531 C MET A 78 -8.606 -0.335 -35.112 1.00 65.96 C ATOM 532 O MET A 78 -9.781 -0.550 -35.414 1.00 61.93 O ATOM 533 CB MET A 78 -8.919 1.830 -33.951 1.00 58.72 C ATOM 534 CG MET A 78 -8.454 3.248 -33.724 1.00 70.11 C ATOM 535 SD MET A 78 -6.842 3.491 -32.939 1.00 85.44 S ATOM 536 CE MET A 78 -5.779 3.924 -34.306 1.00 80.07 C ATOM 537 N LYS A 79 -7.739 -1.304 -34.830 1.00 70.43 N ATOM 538 CA LYS A 79 -8.086 -2.727 -34.912 1.00 73.49 C ATOM 539 C LYS A 79 -7.590 -3.375 -33.610 1.00 71.09 C ATOM 540 O LYS A 79 -6.422 -3.748 -33.477 1.00 79.10 O ATOM 541 CB LYS A 79 -7.499 -3.347 -36.177 1.00 66.70 C ATOM 542 CG LYS A 79 -7.994 -2.670 -37.443 1.00 64.28 C ATOM 543 CD LYS A 79 -7.915 -3.549 -38.729 1.00 74.38 C ATOM 544 N HIS A 80 -8.486 -3.490 -32.633 1.00 72.13 N ATOM 545 CA HIS A 80 -8.098 -3.911 -31.290 1.00 65.82 C ATOM 546 C HIS A 80 -9.377 -4.252 -30.531 1.00 65.94 C ATOM 547 O HIS A 80 -10.442 -3.664 -30.765 1.00 63.27 O ATOM 548 CB HIS A 80 -7.263 -2.832 -30.596 1.00 66.78 C ATOM 549 CG HIS A 80 -6.614 -3.266 -29.305 1.00 72.87 C ATOM 550 ND1 HIS A 80 -5.243 -3.403 -29.170 1.00 72.24 N ATOM 551 CD2 HIS A 80 -7.141 -3.555 -28.090 1.00 67.27 C ATOM 552 CE1 HIS A 80 -4.962 -3.783 -27.940 1.00 74.82 C ATOM 553 NE2 HIS A 80 -6.095 -3.882 -27.265 1.00 73.51 N ATOM 554 N GLU A 81 -9.263 -5.240 -29.630 1.00 61.10 N ATOM 555 CA GLU A 81 -10.445 -5.750 -28.944 1.00 57.89 C ATOM 556 C GLU A 81 -11.025 -4.735 -27.975 1.00 60.16 C ATOM 557 O GLU A 81 -12.245 -4.687 -27.793 1.00 63.09 O ATOM 558 CB GLU A 81 -10.118 -7.040 -28.206 1.00 70.68 C ATOM 559 CG GLU A 81 -9.350 -8.089 -29.024 1.00 81.92 C ATOM 560 CD GLU A 81 -7.877 -7.759 -29.263 1.00 88.97 C ATOM 561 OE1 GLU A 81 -7.468 -6.584 -29.033 1.00 95.40 O ATOM 562 OE2 GLU A 81 -7.153 -8.679 -29.733 1.00107.88 O ATOM 563 N ASN A 82 -10.184 -3.919 -27.345 1.00 56.52 N ATOM 564 CA ASN A 82 -10.663 -2.906 -26.427 1.00 59.22 C ATOM 565 C ASN A 82 -10.786 -1.542 -27.055 1.00 57.34 C ATOM 566 O ASN A 82 -10.914 -0.565 -26.332 1.00 54.65 O ATOM 567 CB ASN A 82 -9.745 -2.795 -25.211 1.00 64.58 C ATOM 568 CG ASN A 82 -9.437 -4.109 -24.615 1.00 61.21 C ATOM 569 OD1 ASN A 82 -8.280 -4.449 -24.463 1.00 64.65 O ATOM 570 ND2 ASN A 82 -10.474 -4.896 -24.328 1.00 57.44 N ATOM 571 N VAL A 83 -10.713 -1.444 -28.376 1.00 61.54 N ATOM 572 CA VAL A 83 -10.832 -0.162 -29.037 1.00 60.94 C ATOM 573 C VAL A 83 -11.903 -0.289 -30.099 1.00 59.23 C ATOM 574 O VAL A 83 -11.810 -1.139 -30.997 1.00 61.65 O ATOM 575 CB VAL A 83 -9.510 0.314 -29.642 1.00 57.67 C ATOM 576 CG1 VAL A 83 -9.678 1.613 -30.415 1.00 59.15 C ATOM 577 CG2 VAL A 83 -8.488 0.520 -28.550 1.00 52.31 C ATOM 578 N ILE A 84 -12.931 0.546 -29.988 1.00 59.10 N ATOM 579 CA ILE A 84 -13.986 0.552 -30.992 1.00 61.28 C ATOM 580 C ILE A 84 -13.370 0.603 -32.382 1.00 62.86 C ATOM 581 O ILE A 84 -12.432 1.397 -32.648 1.00 51.83 O ATOM 582 CB ILE A 84 -14.933 1.727 -30.721 1.00 56.78 C ATOM 583 CG1 ILE A 84 -15.869 1.353 -29.574 1.00 58.71 C ATOM 584 CG2 ILE A 84 -15.698 2.053 -31.919 1.00 60.91 C ATOM 585 CD1 ILE A 84 -17.109 0.630 -29.982 1.00 57.83 C ATOM 586 N GLY A 85 -13.825 -0.328 -33.235 1.00 61.53 N ATOM 587 CA GLY A 85 -13.456 -0.339 -34.629 1.00 62.72 C ATOM 588 C GLY A 85 -14.699 -0.237 -35.504 1.00 58.45 C ATOM 589 O GLY A 85 -15.841 -0.196 -35.028 1.00 59.75 O ATOM 590 N LEU A 86 -14.454 -0.151 -36.797 1.00 59.55 N ATOM 591 CA LEU A 86 -15.538 0.031 -37.760 1.00 68.41 C ATOM 592 C LEU A 86 -15.866 -1.336 -38.367 1.00 62.72 C ATOM 593 O LEU A 86 -14.977 -2.023 -38.896 1.00 53.11 O ATOM 594 CB LEU A 86 -15.157 1.064 -38.841 1.00 67.52 C ATOM 595 CG LEU A 86 -15.399 2.587 -38.714 1.00 61.30 C ATOM 596 CD1 LEU A 86 -15.209 3.219 -40.086 1.00 71.00 C ATOM 597 CD2 LEU A 86 -16.781 2.967 -38.211 1.00 57.47 C ATOM 598 N LEU A 87 -17.126 -1.748 -38.225 1.00 61.61 N ATOM 599 CA LEU A 87 -17.646 -2.830 -39.056 1.00 66.92 C ATOM 600 C LEU A 87 -17.962 -2.325 -40.467 1.00 70.23 C ATOM 601 O LEU A 87 -17.839 -3.076 -41.450 1.00 65.80 O ATOM 602 CB LEU A 87 -18.887 -3.447 -38.399 1.00 58.10 C ATOM 603 CG LEU A 87 -18.607 -4.139 -37.056 1.00 71.64 C ATOM 604 CD1 LEU A 87 -19.842 -4.615 -36.228 1.00 63.81 C ATOM 605 CD2 LEU A 87 -17.661 -5.315 -37.345 1.00 70.46 C ATOM 606 N ASP A 88 -18.327 -1.050 -40.591 1.00 67.87 N ATOM 607 CA ASP A 88 -18.819 -0.541 -41.865 1.00 76.55 C ATOM 608 C ASP A 88 -18.885 0.987 -41.810 1.00 70.82 C ATOM 609 O ASP A 88 -18.951 1.580 -40.727 1.00 67.28 O ATOM 610 CB ASP A 88 -20.191 -1.167 -42.172 1.00 69.35 C ATOM 611 CG ASP A 88 -20.732 -0.796 -43.521 1.00 76.14 C ATOM 612 OD1 ASP A 88 -19.946 -0.465 -44.433 1.00 72.52 O ATOM 613 OD2 ASP A 88 -21.975 -0.831 -43.656 1.00 80.49 O ATOM 614 N VAL A 89 -18.796 1.614 -42.985 1.00 72.87 N ATOM 615 CA VAL A 89 -19.101 3.037 -43.152 1.00 75.81 C ATOM 616 C VAL A 89 -19.754 3.234 -44.508 1.00 70.90 C ATOM 617 O VAL A 89 -19.264 2.729 -45.523 1.00 74.39 O ATOM 618 CB VAL A 89 -17.877 3.966 -43.024 1.00 72.02 C ATOM 619 CG1 VAL A 89 -16.748 3.539 -43.944 1.00 68.52 C ATOM 620 CG2 VAL A 89 -18.299 5.368 -43.361 1.00 67.18 C ATOM 621 N PHE A 90 -20.866 3.958 -44.524 1.00 72.22 N ATOM 622 CA PHE A 90 -21.628 4.143 -45.749 1.00 81.15 C ATOM 623 C PHE A 90 -22.236 5.541 -45.756 1.00 80.97 C ATOM 624 O PHE A 90 -22.335 6.209 -44.714 1.00 78.85 O ATOM 625 CB PHE A 90 -22.725 3.065 -45.891 1.00 73.62 C ATOM 626 CG PHE A 90 -23.724 3.070 -44.767 1.00 75.80 C ATOM 627 CD1 PHE A 90 -24.827 3.914 -44.799 1.00 79.25 C ATOM 628 CD2 PHE A 90 -23.536 2.266 -43.644 1.00 72.40 C ATOM 629 CE1 PHE A 90 -25.737 3.950 -43.739 1.00 81.92 C ATOM 630 CE2 PHE A 90 -24.440 2.281 -42.595 1.00 70.08 C ATOM 631 CZ PHE A 90 -25.540 3.120 -42.638 1.00 76.57 C ATOM 632 N THR A 91 -22.643 5.959 -46.954 1.00 79.07 N ATOM 633 CA THR A 91 -23.420 7.162 -47.215 1.00 82.83 C ATOM 634 C THR A 91 -24.466 6.828 -48.268 1.00 82.92 C ATOM 635 O THR A 91 -24.221 5.983 -49.141 1.00 76.65 O ATOM 636 CB THR A 91 -22.543 8.331 -47.703 1.00 85.78 C ATOM 637 OG1 THR A 91 -23.353 9.508 -47.892 1.00 90.60 O ATOM 638 CG2 THR A 91 -21.845 7.983 -49.033 1.00 83.39 C ATOM 639 N PRO A 92 -25.647 7.454 -48.199 1.00 78.28 N ATOM 640 CA PRO A 92 -26.635 7.280 -49.267 1.00 86.81 C ATOM 641 C PRO A 92 -26.208 7.841 -50.621 1.00 92.52 C ATOM 642 O PRO A 92 -26.808 7.458 -51.636 1.00 90.89 O ATOM 643 CB PRO A 92 -27.869 8.011 -48.727 1.00 80.77 C ATOM 644 CG PRO A 92 -27.400 8.857 -47.667 1.00 87.52 C ATOM 645 CD PRO A 92 -26.219 8.178 -47.060 1.00 87.42 C ATOM 646 N ALA A 93 -25.183 8.686 -50.686 1.00 85.75 N ATOM 647 CA ALA A 93 -24.841 9.346 -51.938 1.00 95.44 C ATOM 648 C ALA A 93 -24.089 8.413 -52.874 1.00 96.63 C ATOM 649 O ALA A 93 -23.201 7.670 -52.447 1.00 86.33 O ATOM 650 CB ALA A 93 -23.997 10.590 -51.670 1.00100.82 C ATOM 651 N ARG A 94 -24.427 8.491 -54.171 1.00104.10 N ATOM 652 CA ARG A 94 -23.866 7.602 -55.185 1.00 98.50 C ATOM 653 C ARG A 94 -22.639 8.176 -55.890 1.00102.67 C ATOM 654 O ARG A 94 -21.982 7.448 -56.639 1.00106.59 O ATOM 655 CB ARG A 94 -24.939 7.227 -56.217 1.00 90.18 C ATOM 656 N SER A 95 -22.306 9.446 -55.677 1.00106.23 N ATOM 657 CA SER A 95 -21.011 9.968 -56.099 1.00105.36 C ATOM 658 C SER A 95 -20.677 11.177 -55.238 1.00106.90 C ATOM 659 O SER A 95 -21.512 11.679 -54.476 1.00106.90 O ATOM 660 CB SER A 95 -20.971 10.335 -57.585 1.00112.03 C ATOM 661 OG SER A 95 -19.631 10.561 -58.004 1.00115.97 O ATOM 662 N LEU A 96 -19.432 11.641 -55.378 1.00106.30 N ATOM 663 CA LEU A 96 -18.944 12.734 -54.546 1.00106.91 C ATOM 664 C LEU A 96 -19.837 13.964 -54.644 1.00110.70 C ATOM 665 O LEU A 96 -20.041 14.664 -53.646 1.00107.89 O ATOM 666 CB LEU A 96 -17.506 13.080 -54.945 1.00106.81 C ATOM 667 CG LEU A 96 -16.817 14.167 -54.119 1.00100.23 C ATOM 668 N GLU A 97 -20.399 14.225 -55.829 1.00113.72 N ATOM 669 CA GLU A 97 -21.184 15.436 -56.034 1.00115.05 C ATOM 670 C GLU A 97 -22.421 15.497 -55.147 1.00112.64 C ATOM 671 O GLU A 97 -22.930 16.595 -54.895 1.00114.54 O ATOM 672 CB GLU A 97 -21.585 15.552 -57.506 1.00113.84 C ATOM 673 CG GLU A 97 -20.452 16.011 -58.399 1.00118.42 C ATOM 674 CD GLU A 97 -19.607 14.864 -58.908 1.00117.58 C ATOM 675 OE1 GLU A 97 -18.362 14.965 -58.820 1.00117.25 O ATOM 676 OE2 GLU A 97 -20.187 13.872 -59.403 1.00117.91 O ATOM 677 N GLU A 98 -22.914 14.359 -54.664 1.00106.37 N ATOM 678 CA GLU A 98 -24.015 14.363 -53.714 1.00108.30 C ATOM 679 C GLU A 98 -23.603 13.921 -52.312 1.00107.22 C ATOM 680 O GLU A 98 -24.459 13.841 -51.422 1.00109.69 O ATOM 681 CB GLU A 98 -25.158 13.488 -54.249 1.00106.64 C ATOM 682 CG GLU A 98 -24.718 12.164 -54.836 1.00108.68 C ATOM 683 CD GLU A 98 -25.903 11.303 -55.230 1.00109.61 C ATOM 684 OE1 GLU A 98 -26.892 11.880 -55.728 1.00120.23 O ATOM 685 OE2 GLU A 98 -25.863 10.066 -55.023 1.00103.08 O ATOM 686 N PHE A 99 -22.314 13.669 -52.083 1.00106.75 N ATOM 687 CA PHE A 99 -21.788 13.257 -50.782 1.00 98.68 C ATOM 688 C PHE A 99 -22.086 14.277 -49.679 1.00101.48 C ATOM 689 O PHE A 99 -21.530 15.380 -49.682 1.00103.13 O ATOM 690 CB PHE A 99 -20.284 13.016 -50.926 1.00 94.36 C ATOM 691 CG PHE A 99 -19.633 12.506 -49.700 1.00 95.97 C ATOM 692 CD1 PHE A 99 -20.218 11.496 -48.952 1.00 98.66 C ATOM 693 CD2 PHE A 99 -18.431 13.038 -49.273 1.00 97.73 C ATOM 694 CE1 PHE A 99 -19.615 11.029 -47.801 1.00 87.31 C ATOM 695 CE2 PHE A 99 -17.824 12.569 -48.118 1.00 89.69 C ATOM 696 CZ PHE A 99 -18.413 11.564 -47.390 1.00 86.90 C ATOM 697 N ASN A 100 -22.943 13.921 -48.711 1.00104.47 N ATOM 698 CA ASN A 100 -23.399 14.895 -47.715 1.00101.33 C ATOM 699 C ASN A 100 -23.422 14.367 -46.288 1.00100.05 C ATOM 700 O ASN A 100 -23.188 15.121 -45.338 1.00102.90 O ATOM 701 CB ASN A 100 -24.800 15.380 -48.070 1.00107.50 C ATOM 702 CG ASN A 100 -24.818 16.226 -49.325 1.00105.75 C ATOM 703 OD1 ASN A 100 -25.538 15.925 -50.276 1.00105.74 O ATOM 704 ND2 ASN A 100 -24.033 17.295 -49.330 1.00107.92 N ATOM 705 N ASP A 101 -23.747 13.095 -46.111 1.00 98.18 N ATOM 706 CA ASP A 101 -23.913 12.524 -44.786 1.00 97.80 C ATOM 707 C ASP A 101 -23.001 11.316 -44.652 1.00 96.91 C ATOM 708 O ASP A 101 -22.622 10.707 -45.655 1.00 91.96 O ATOM 709 CB ASP A 101 -25.378 12.139 -44.532 1.00 98.67 C ATOM 710 CG ASP A 101 -26.246 13.348 -44.191 1.00106.76 C ATOM 711 OD1 ASP A 101 -25.691 14.362 -43.693 1.00104.76 O ATOM 712 OD2 ASP A 101 -27.477 13.280 -44.401 1.00105.92 O ATOM 713 N VAL A 102 -22.600 10.993 -43.418 1.00 93.10 N ATOM 714 CA VAL A 102 -21.717 9.851 -43.186 1.00 84.62 C ATOM 715 C VAL A 102 -22.175 9.087 -41.948 1.00 80.80 C ATOM 716 O VAL A 102 -22.480 9.678 -40.910 1.00 81.73 O ATOM 717 CB VAL A 102 -20.233 10.262 -43.085 1.00 85.26 C ATOM 718 CG1 VAL A 102 -19.824 11.178 -44.253 1.00 90.97 C ATOM 719 CG2 VAL A 102 -20.000 11.000 -41.840 1.00 85.97 C ATOM 720 N TYR A 103 -22.256 7.773 -42.079 1.00 82.13 N ATOM 721 CA TYR A 103 -22.714 6.891 -41.024 1.00 74.39 C ATOM 722 C TYR A 103 -21.573 5.964 -40.664 1.00 72.29 C ATOM 723 O TYR A 103 -20.917 5.414 -41.551 1.00 71.69 O ATOM 724 CB TYR A 103 -23.922 6.071 -41.463 1.00 76.96 C ATOM 725 CG TYR A 103 -25.108 6.881 -41.914 1.00 81.08 C ATOM 726 CD1 TYR A 103 -25.237 7.270 -43.245 1.00 82.76 C ATOM 727 CD2 TYR A 103 -26.100 7.244 -41.022 1.00 81.19 C ATOM 728 CE1 TYR A 103 -26.335 8.021 -43.654 1.00 88.64 C ATOM 729 CE2 TYR A 103 -27.194 7.994 -41.420 1.00 79.35 C ATOM 730 CZ TYR A 103 -27.308 8.377 -42.732 1.00 85.18 C ATOM 731 OH TYR A 103 -28.401 9.116 -43.133 1.00 99.85 O ATOM 732 N LEU A 104 -21.325 5.795 -39.371 1.00 65.38 N ATOM 733 CA LEU A 104 -20.312 4.865 -38.913 1.00 60.01 C ATOM 734 C LEU A 104 -21.035 3.769 -38.149 1.00 57.14 C ATOM 735 O LEU A 104 -22.090 4.031 -37.579 1.00 59.70 O ATOM 736 CB LEU A 104 -19.299 5.594 -38.059 1.00 61.60 C ATOM 737 CG LEU A 104 -18.750 6.958 -38.462 1.00 59.00 C ATOM 738 CD1 LEU A 104 -18.264 7.608 -37.150 1.00 66.01 C ATOM 739 CD2 LEU A 104 -17.605 6.803 -39.346 1.00 48.74 C ATOM 740 N VAL A 105 -20.529 2.531 -38.187 1.00 54.26 N ATOM 741 CA VAL A 105 -21.202 1.409 -37.517 1.00 61.18 C ATOM 742 C VAL A 105 -20.172 0.523 -36.824 1.00 57.22 C ATOM 743 O VAL A 105 -19.041 0.369 -37.300 1.00 56.47 O ATOM 744 CB VAL A 105 -22.128 0.597 -38.471 1.00 63.71 C ATOM 745 CG1 VAL A 105 -21.468 0.301 -39.703 1.00 64.62 C ATOM 746 CG2 VAL A 105 -22.558 -0.721 -37.876 1.00 60.38 C ATOM 747 N THR A 106 -20.539 0.010 -35.649 1.00 55.31 N ATOM 748 CA THR A 106 -19.623 -0.770 -34.834 1.00 57.34 C ATOM 749 C THR A 106 -20.425 -1.834 -34.102 1.00 53.26 C ATOM 750 O THR A 106 -21.659 -1.820 -34.113 1.00 54.96 O ATOM 751 CB THR A 106 -18.854 0.152 -33.858 1.00 57.46 C ATOM 752 OG1 THR A 106 -17.627 -0.457 -33.465 1.00 55.04 O ATOM 753 CG2 THR A 106 -19.703 0.462 -32.627 1.00 58.22 C ATOM 754 N HIS A 107 -19.722 -2.801 -33.517 1.00 56.33 N ATOM 755 CA HIS A 107 -20.399 -3.759 -32.643 1.00 65.87 C ATOM 756 C HIS A 107 -21.142 -3.021 -31.544 1.00 63.44 C ATOM 757 O HIS A 107 -20.595 -2.095 -30.937 1.00 58.95 O ATOM 758 CB HIS A 107 -19.409 -4.717 -31.987 1.00 67.37 C ATOM 759 CG HIS A 107 -18.555 -5.454 -32.952 1.00 75.32 C ATOM 760 ND1 HIS A 107 -18.914 -6.678 -33.475 1.00 87.19 N ATOM 761 CD2 HIS A 107 -17.344 -5.160 -33.476 1.00 78.40 C ATOM 762 CE1 HIS A 107 -17.965 -7.104 -34.291 1.00 85.66 C ATOM 763 NE2 HIS A 107 -16.997 -6.204 -34.304 1.00 89.26 N ATOM 764 N LEU A 108 -22.384 -3.439 -31.304 1.00 64.90 N ATOM 765 CA LEU A 108 -23.238 -2.794 -30.324 1.00 62.11 C ATOM 766 C LEU A 108 -22.793 -3.212 -28.933 1.00 63.76 C ATOM 767 O LEU A 108 -22.684 -4.409 -28.638 1.00 70.68 O ATOM 768 CB LEU A 108 -24.700 -3.154 -30.546 1.00 62.95 C ATOM 769 CG LEU A 108 -25.688 -2.534 -29.536 1.00 68.64 C ATOM 770 CD1 LEU A 108 -25.772 -0.971 -29.561 1.00 61.66 C ATOM 771 CD2 LEU A 108 -27.082 -3.122 -29.717 1.00 71.62 C ATOM 772 N MET A 109 -22.497 -2.241 -28.086 1.00 64.65 N ATOM 773 CA MET A 109 -22.140 -2.536 -26.706 1.00 61.92 C ATOM 774 C MET A 109 -23.312 -2.141 -25.812 1.00 53.42 C ATOM 775 O MET A 109 -24.068 -1.226 -26.130 1.00 64.57 O ATOM 776 CB MET A 109 -20.850 -1.803 -26.343 1.00 63.80 C ATOM 777 CG MET A 109 -19.674 -2.114 -27.344 1.00 61.84 C ATOM 778 SD MET A 109 -18.880 -3.712 -27.016 1.00 61.54 S ATOM 779 CE MET A 109 -18.300 -3.541 -25.323 1.00 65.12 C ATOM 780 N GLY A 110 -23.516 -2.863 -24.727 1.00 60.64 N ATOM 781 CA GLY A 110 -24.713 -2.602 -23.949 1.00 66.55 C ATOM 782 C GLY A 110 -24.681 -1.382 -23.032 1.00 70.96 C ATOM 783 O GLY A 110 -25.701 -0.686 -22.892 1.00 66.22 O ATOM 784 N ALA A 111 -23.534 -1.084 -22.415 1.00 60.26 N ATOM 785 CA ALA A 111 -23.471 0.025 -21.465 1.00 63.27 C ATOM 786 C ALA A 111 -22.110 0.723 -21.535 1.00 59.95 C ATOM 787 O ALA A 111 -21.194 0.311 -22.266 1.00 57.07 O ATOM 788 CB ALA A 111 -23.730 -0.460 -20.036 1.00 60.74 C ATOM 789 N ASP A 112 -22.012 1.813 -20.777 1.00 61.95 N ATOM 790 CA ASP A 112 -20.780 2.533 -20.509 1.00 61.59 C ATOM 791 C ASP A 112 -20.546 2.550 -19.002 1.00 60.11 C ATOM 792 O ASP A 112 -21.491 2.418 -18.222 1.00 64.30 O ATOM 793 CB ASP A 112 -20.846 3.966 -21.048 1.00 60.27 C ATOM 794 CG ASP A 112 -21.911 4.813 -20.344 1.00 65.42 C ATOM 795 OD1 ASP A 112 -21.758 5.049 -19.136 1.00 72.74 O ATOM 796 OD2 ASP A 112 -22.902 5.234 -20.964 1.00 65.41 O ATOM 797 N LEU A 113 -19.279 2.739 -18.587 1.00 62.67 N ATOM 798 CA LEU A 113 -18.913 2.563 -17.174 1.00 63.33 C ATOM 799 C LEU A 113 -19.632 3.547 -16.265 1.00 64.71 C ATOM 800 O LEU A 113 -19.774 3.290 -15.071 1.00 68.93 O ATOM 801 CB LEU A 113 -17.407 2.689 -16.959 1.00 54.66 C ATOM 802 CG LEU A 113 -16.551 1.443 -17.230 1.00 55.51 C ATOM 803 CD1 LEU A 113 -15.088 1.615 -16.805 1.00 54.47 C ATOM 804 CD2 LEU A 113 -17.152 0.153 -16.661 1.00 57.74 C ATOM 805 N ASN A 114 -20.094 4.663 -16.809 1.00 71.39 N ATOM 806 CA ASN A 114 -20.905 5.590 -16.040 1.00 71.05 C ATOM 807 C ASN A 114 -22.208 4.925 -15.604 1.00 75.98 C ATOM 808 O ASN A 114 -22.563 4.947 -14.416 1.00 81.88 O ATOM 809 CB ASN A 114 -21.139 6.837 -16.888 1.00 73.44 C ATOM 810 CG ASN A 114 -21.747 7.962 -16.113 1.00 78.99 C ATOM 811 OD1 ASN A 114 -21.099 8.551 -15.252 1.00 87.86 O ATOM 812 ND2 ASN A 114 -22.989 8.305 -16.441 1.00 81.43 N ATOM 813 N ASN A 115 -22.902 4.263 -16.537 1.00 74.91 N ATOM 814 CA ASN A 115 -24.119 3.543 -16.177 1.00 74.30 C ATOM 815 C ASN A 115 -23.854 2.374 -15.243 1.00 79.47 C ATOM 816 O ASN A 115 -24.690 2.085 -14.386 1.00 89.33 O ATOM 817 CB ASN A 115 -24.830 3.030 -17.425 1.00 81.86 C ATOM 818 CG ASN A 115 -25.248 4.156 -18.367 1.00 87.28 C ATOM 819 OD1 ASN A 115 -25.546 5.281 -17.922 1.00 84.06 O ATOM 820 ND2 ASN A 115 -25.277 3.859 -19.669 1.00 74.47 N ATOM 821 N ILE A 116 -22.711 1.701 -15.367 1.00 71.69 N ATOM 822 CA ILE A 116 -22.456 0.532 -14.524 1.00 69.75 C ATOM 823 C ILE A 116 -22.292 0.947 -13.065 1.00 81.43 C ATOM 824 O ILE A 116 -23.022 0.490 -12.178 1.00 82.87 O ATOM 825 CB ILE A 116 -21.221 -0.231 -15.025 1.00 67.57 C ATOM 826 CG1 ILE A 116 -21.500 -0.887 -16.392 1.00 68.65 C ATOM 827 CG2 ILE A 116 -20.751 -1.242 -14.003 1.00 68.57 C ATOM 828 CD1 ILE A 116 -22.954 -1.247 -16.638 1.00 70.11 C ATOM 829 N VAL A 117 -21.322 1.821 -12.793 1.00 80.19 N ATOM 830 CA VAL A 117 -21.055 2.205 -11.418 1.00 80.75 C ATOM 831 C VAL A 117 -22.281 2.866 -10.796 1.00 82.10 C ATOM 832 O VAL A 117 -22.495 2.775 -9.580 1.00 81.72 O ATOM 833 CB VAL A 117 -19.807 3.105 -11.360 1.00 77.56 C ATOM 834 CG1 VAL A 117 -20.101 4.497 -11.951 1.00 80.89 C ATOM 835 CG2 VAL A 117 -19.311 3.179 -9.925 1.00 79.57 C ATOM 836 N LYS A 118 -23.137 3.479 -11.622 1.00 84.38 N ATOM 837 CA LYS A 118 -24.373 4.100 -11.158 1.00 80.80 C ATOM 838 C LYS A 118 -25.465 3.099 -10.843 1.00 91.49 C ATOM 839 O LYS A 118 -26.585 3.533 -10.548 1.00 95.15 O ATOM 840 CB LYS A 118 -24.912 5.081 -12.194 1.00 82.03 C ATOM 841 N CYS A 119 -25.196 1.791 -10.944 1.00 86.21 N ATOM 842 CA CYS A 119 -26.194 0.788 -10.609 1.00 84.20 C ATOM 843 C CYS A 119 -25.633 -0.451 -9.941 1.00 86.14 C ATOM 844 O CYS A 119 -26.403 -1.390 -9.723 1.00 85.92 O ATOM 845 CB CYS A 119 -26.966 0.327 -11.854 1.00 86.32 C ATOM 846 SG CYS A 119 -27.426 1.591 -12.989 1.00103.65 S ATOM 847 N GLN A 120 -24.330 -0.523 -9.664 1.00 85.71 N ATOM 848 CA GLN A 120 -23.768 -1.683 -8.977 1.00 87.13 C ATOM 849 C GLN A 120 -22.473 -1.302 -8.295 1.00 76.81 C ATOM 850 O GLN A 120 -21.778 -0.372 -8.703 1.00 76.47 O ATOM 851 CB GLN A 120 -23.406 -2.837 -9.920 1.00 85.73 C ATOM 852 CG GLN A 120 -24.511 -3.364 -10.723 1.00 93.13 C ATOM 853 CD GLN A 120 -24.108 -3.547 -12.169 1.00 91.51 C ATOM 854 OE1 GLN A 120 -24.807 -3.067 -13.062 1.00 89.03 O ATOM 855 NE2 GLN A 120 -23.035 -4.299 -12.415 1.00 88.10 N ATOM 856 N LYS A 121 -22.109 -2.119 -7.323 1.00 81.07 N ATOM 857 CA LYS A 121 -20.758 -2.136 -6.814 1.00 84.79 C ATOM 858 C LYS A 121 -19.907 -3.063 -7.679 1.00 75.78 C ATOM 859 O LYS A 121 -20.402 -3.759 -8.567 1.00 81.53 O ATOM 860 CB LYS A 121 -20.752 -2.541 -5.345 1.00 87.99 C ATOM 861 N LEU A 122 -18.601 -3.052 -7.437 1.00 69.34 N ATOM 862 CA LEU A 122 -17.665 -3.729 -8.324 1.00 74.75 C ATOM 863 C LEU A 122 -16.559 -4.337 -7.488 1.00 75.11 C ATOM 864 O LEU A 122 -15.987 -3.668 -6.629 1.00 78.25 O ATOM 865 CB LEU A 122 -17.048 -2.773 -9.370 1.00 72.29 C ATOM 866 CG LEU A 122 -17.964 -2.059 -10.358 1.00 71.53 C ATOM 867 CD1 LEU A 122 -17.216 -0.886 -11.018 1.00 72.23 C ATOM 868 CD2 LEU A 122 -18.501 -3.061 -11.414 1.00 73.44 C ATOM 869 N THR A 123 -16.230 -5.583 -7.785 1.00 73.57 N ATOM 870 CA THR A 123 -15.241 -6.306 -7.010 1.00 82.71 C ATOM 871 C THR A 123 -13.843 -5.914 -7.417 1.00 78.65 C ATOM 872 O THR A 123 -13.631 -5.209 -8.384 1.00 77.12 O ATOM 873 CB THR A 123 -15.401 -7.814 -7.182 1.00 84.29 C ATOM 874 OG1 THR A 123 -14.916 -8.189 -8.492 1.00 83.45 O ATOM 875 CG2 THR A 123 -16.862 -8.216 -7.006 1.00 85.95 C ATOM 876 N ASP A 124 -12.865 -6.413 -6.670 1.00 86.51 N ATOM 877 CA ASP A 124 -11.507 -6.190 -7.128 1.00 86.74 C ATOM 878 C ASP A 124 -11.246 -6.970 -8.401 1.00 83.10 C ATOM 879 O ASP A 124 -10.420 -6.557 -9.214 1.00 83.25 O ATOM 880 CB ASP A 124 -10.493 -6.560 -6.057 1.00 86.36 C ATOM 881 CG ASP A 124 -9.084 -6.179 -6.453 1.00 92.19 C ATOM 882 OD1 ASP A 124 -8.800 -4.967 -6.551 1.00 89.80 O ATOM 883 OD2 ASP A 124 -8.264 -7.089 -6.691 1.00100.96 O ATOM 884 N ASP A 125 -11.947 -8.091 -8.587 1.00 81.90 N ATOM 885 CA ASP A 125 -11.822 -8.842 -9.824 1.00 82.93 C ATOM 886 C ASP A 125 -12.372 -8.042 -10.996 1.00 79.31 C ATOM 887 O ASP A 125 -11.773 -8.020 -12.072 1.00 72.48 O ATOM 888 CB ASP A 125 -12.533 -10.186 -9.699 1.00 85.15 C ATOM 889 CG ASP A 125 -11.967 -11.027 -8.587 1.00 96.45 C ATOM 890 OD1 ASP A 125 -12.741 -11.443 -7.687 1.00101.95 O ATOM 891 OD2 ASP A 125 -10.736 -11.256 -8.617 1.00 97.10 O ATOM 892 N HIS A 126 -13.507 -7.371 -10.796 1.00 76.28 N ATOM 893 CA HIS A 126 -14.068 -6.516 -11.831 1.00 75.54 C ATOM 894 C HIS A 126 -13.100 -5.406 -12.205 1.00 79.32 C ATOM 895 O HIS A 126 -12.751 -5.245 -13.385 1.00 78.57 O ATOM 896 CB HIS A 126 -15.393 -5.934 -11.360 1.00 79.39 C ATOM 897 CG HIS A 126 -16.489 -6.947 -11.279 1.00 86.99 C ATOM 898 ND1 HIS A 126 -16.982 -7.417 -10.078 1.00 87.67 N ATOM 899 CD2 HIS A 126 -17.184 -7.585 -12.251 1.00 84.48 C ATOM 900 CE1 HIS A 126 -17.931 -8.304 -10.314 1.00 91.25 C ATOM 901 NE2 HIS A 126 -18.075 -8.422 -11.624 1.00 92.14 N ATOM 902 N VAL A 127 -12.651 -4.627 -11.214 1.00 70.31 N ATOM 903 CA VAL A 127 -11.779 -3.509 -11.541 1.00 78.06 C ATOM 904 C VAL A 127 -10.441 -4.021 -12.059 1.00 78.44 C ATOM 905 O VAL A 127 -9.763 -3.334 -12.829 1.00 79.42 O ATOM 906 CB VAL A 127 -11.639 -2.559 -10.326 1.00 73.71 C ATOM 907 CG1 VAL A 127 -11.365 -3.326 -9.119 1.00 88.01 C ATOM 908 CG2 VAL A 127 -10.508 -1.575 -10.514 1.00 72.78 C ATOM 909 N GLN A 128 -10.040 -5.225 -11.660 1.00 77.47 N ATOM 910 CA GLN A 128 -8.807 -5.809 -12.179 1.00 78.21 C ATOM 911 C GLN A 128 -8.888 -5.890 -13.690 1.00 81.81 C ATOM 912 O GLN A 128 -8.033 -5.379 -14.432 1.00 79.09 O ATOM 913 CB GLN A 128 -8.596 -7.226 -11.602 1.00 83.38 C ATOM 914 CG GLN A 128 -7.753 -7.379 -10.308 1.00 94.41 C ATOM 915 CD GLN A 128 -7.166 -8.796 -10.120 1.00 90.13 C ATOM 916 OE1 GLN A 128 -6.010 -8.939 -9.734 1.00 95.13 O ATOM 917 NE2 GLN A 128 -7.965 -9.830 -10.385 1.00 84.61 N ATOM 918 N PHE A 129 -9.956 -6.540 -14.144 1.00 75.04 N ATOM 919 CA PHE A 129 -10.168 -6.816 -15.546 1.00 69.27 C ATOM 920 C PHE A 129 -10.484 -5.533 -16.318 1.00 70.73 C ATOM 921 O PHE A 129 -9.873 -5.265 -17.361 1.00 70.42 O ATOM 922 CB PHE A 129 -11.299 -7.843 -15.651 1.00 71.13 C ATOM 923 CG PHE A 129 -11.487 -8.418 -17.022 1.00 65.97 C ATOM 924 CD1 PHE A 129 -10.402 -8.649 -17.831 1.00 59.94 C ATOM 925 CD2 PHE A 129 -12.755 -8.747 -17.462 1.00 66.91 C ATOM 926 CE1 PHE A 129 -10.569 -9.179 -19.073 1.00 62.39 C ATOM 927 CE2 PHE A 129 -12.945 -9.276 -18.709 1.00 66.69 C ATOM 928 CZ PHE A 129 -11.850 -9.499 -19.525 1.00 63.99 C ATOM 929 N LEU A 130 -11.432 -4.724 -15.818 1.00 64.49 N ATOM 930 CA LEU A 130 -11.799 -3.491 -16.511 1.00 66.95 C ATOM 931 C LEU A 130 -10.573 -2.614 -16.721 1.00 69.90 C ATOM 932 O LEU A 130 -10.214 -2.289 -17.866 1.00 66.33 O ATOM 933 CB LEU A 130 -12.868 -2.713 -15.744 1.00 59.91 C ATOM 934 CG LEU A 130 -14.273 -3.304 -15.659 1.00 63.12 C ATOM 935 CD1 LEU A 130 -15.202 -2.428 -14.832 1.00 61.21 C ATOM 936 CD2 LEU A 130 -14.876 -3.566 -17.054 1.00 66.84 C ATOM 937 N ILE A 131 -9.909 -2.231 -15.620 1.00 67.38 N ATOM 938 CA ILE A 131 -8.720 -1.402 -15.744 1.00 65.94 C ATOM 939 C ILE A 131 -7.744 -2.047 -16.706 1.00 69.03 C ATOM 940 O ILE A 131 -7.327 -1.414 -17.680 1.00 75.29 O ATOM 941 CB ILE A 131 -8.086 -1.137 -14.376 1.00 67.61 C ATOM 942 CG1 ILE A 131 -9.068 -0.328 -13.557 1.00 68.90 C ATOM 943 CG2 ILE A 131 -6.823 -0.340 -14.510 1.00 64.93 C ATOM 944 CD1 ILE A 131 -9.497 0.960 -14.287 1.00 65.17 C ATOM 945 N TYR A 132 -7.470 -3.349 -16.538 1.00 68.22 N ATOM 946 CA TYR A 132 -6.586 -4.054 -17.473 1.00 72.15 C ATOM 947 C TYR A 132 -6.929 -3.707 -18.917 1.00 63.25 C ATOM 948 O TYR A 132 -6.056 -3.319 -19.693 1.00 67.17 O ATOM 949 CB TYR A 132 -6.647 -5.583 -17.267 1.00 75.67 C ATOM 950 CG TYR A 132 -5.785 -6.322 -18.278 1.00 73.86 C ATOM 951 CD1 TYR A 132 -4.414 -6.094 -18.335 1.00 81.60 C ATOM 952 CD2 TYR A 132 -6.331 -7.242 -19.166 1.00 72.95 C ATOM 953 CE1 TYR A 132 -3.602 -6.754 -19.267 1.00 86.31 C ATOM 954 CE2 TYR A 132 -5.517 -7.915 -20.097 1.00 80.57 C ATOM 955 CZ TYR A 132 -4.155 -7.661 -20.133 1.00 81.67 C ATOM 956 OH TYR A 132 -3.332 -8.309 -21.027 1.00 84.20 O ATOM 957 N GLN A 133 -8.203 -3.816 -19.286 1.00 63.99 N ATOM 958 CA GLN A 133 -8.568 -3.664 -20.695 1.00 65.02 C ATOM 959 C GLN A 133 -8.278 -2.246 -21.178 1.00 66.70 C ATOM 960 O GLN A 133 -7.723 -2.052 -22.269 1.00 58.41 O ATOM 961 CB GLN A 133 -10.050 -4.005 -20.894 1.00 59.30 C ATOM 962 CG GLN A 133 -10.346 -5.480 -20.761 1.00 61.24 C ATOM 963 CD GLN A 133 -11.815 -5.868 -20.949 1.00 65.63 C ATOM 964 OE1 GLN A 133 -12.247 -6.138 -22.100 1.00 66.18 O ATOM 965 NE2 GLN A 133 -12.549 -6.030 -19.842 1.00 55.89 N ATOM 966 N ILE A 134 -8.590 -1.243 -20.341 1.00 62.43 N ATOM 967 CA ILE A 134 -8.299 0.132 -20.717 1.00 65.27 C ATOM 968 C ILE A 134 -6.822 0.324 -21.048 1.00 68.39 C ATOM 969 O ILE A 134 -6.491 0.956 -22.049 1.00 62.30 O ATOM 970 CB ILE A 134 -8.739 1.096 -19.616 1.00 64.54 C ATOM 971 CG1 ILE A 134 -10.234 0.928 -19.313 1.00 60.69 C ATOM 972 CG2 ILE A 134 -8.360 2.497 -20.063 1.00 61.16 C ATOM 973 CD1 ILE A 134 -10.636 1.614 -18.030 1.00 66.17 C ATOM 974 N LEU A 135 -5.900 -0.203 -20.225 1.00 66.87 N ATOM 975 CA LEU A 135 -4.495 0.099 -20.536 1.00 68.08 C ATOM 976 C LEU A 135 -3.973 -0.746 -21.691 1.00 70.11 C ATOM 977 O LEU A 135 -2.922 -0.439 -22.267 1.00 70.68 O ATOM 978 CB LEU A 135 -3.574 -0.007 -19.338 1.00 78.35 C ATOM 979 CG LEU A 135 -4.001 0.662 -18.028 1.00 76.12 C ATOM 980 CD1 LEU A 135 -4.626 -0.368 -17.109 1.00 71.00 C ATOM 981 CD2 LEU A 135 -2.853 1.449 -17.351 1.00 86.70 C ATOM 982 N ARG A 136 -4.669 -1.813 -22.048 1.00 63.11 N ATOM 983 CA ARG A 136 -4.308 -2.530 -23.261 1.00 69.05 C ATOM 984 C ARG A 136 -4.698 -1.707 -24.492 1.00 70.05 C ATOM 985 O ARG A 136 -3.889 -1.498 -25.405 1.00 71.56 O ATOM 986 CB ARG A 136 -4.987 -3.902 -23.252 1.00 68.65 C ATOM 987 CG ARG A 136 -4.576 -4.825 -24.360 1.00 79.94 C ATOM 988 CD ARG A 136 -5.140 -6.218 -24.107 1.00 79.60 C ATOM 989 NE ARG A 136 -4.906 -7.159 -25.195 1.00 80.18 N ATOM 990 CZ ARG A 136 -5.757 -7.333 -26.200 1.00 91.25 C ATOM 991 NH1 ARG A 136 -6.866 -6.595 -26.233 1.00 80.24 N ATOM 992 NH2 ARG A 136 -5.503 -8.221 -27.176 1.00 86.43 N ATOM 993 N GLY A 137 -5.938 -1.210 -24.509 1.00 65.50 N ATOM 994 CA GLY A 137 -6.319 -0.187 -25.462 1.00 61.42 C ATOM 995 C GLY A 137 -5.332 0.960 -25.484 1.00 66.78 C ATOM 996 O GLY A 137 -4.778 1.297 -26.536 1.00 64.21 O ATOM 997 N LEU A 138 -5.068 1.557 -24.307 1.00 68.14 N ATOM 998 CA LEU A 138 -4.209 2.739 -24.246 1.00 66.66 C ATOM 999 C LEU A 138 -2.807 2.456 -24.773 1.00 72.09 C ATOM 1000 O LEU A 138 -2.210 3.320 -25.433 1.00 64.11 O ATOM 1001 CB LEU A 138 -4.143 3.252 -22.815 1.00 68.88 C ATOM 1002 CG LEU A 138 -5.218 4.311 -22.572 1.00 63.22 C ATOM 1003 CD1 LEU A 138 -4.991 4.951 -21.231 1.00 63.55 C ATOM 1004 CD2 LEU A 138 -5.229 5.340 -23.716 1.00 58.15 C ATOM 1005 N LYS A 139 -2.260 1.259 -24.485 1.00 74.61 N ATOM 1006 CA LYS A 139 -0.960 0.880 -25.038 1.00 71.39 C ATOM 1007 C LYS A 139 -1.020 0.886 -26.546 1.00 72.55 C ATOM 1008 O LYS A 139 -0.196 1.514 -27.226 1.00 78.03 O ATOM 1009 CB LYS A 139 -0.533 -0.496 -24.531 1.00 79.27 C ATOM 1010 CG LYS A 139 0.735 -1.061 -25.200 1.00 76.35 C ATOM 1011 N TYR A 140 -2.038 0.237 -27.083 1.00 74.27 N ATOM 1012 CA TYR A 140 -2.258 0.237 -28.519 1.00 74.43 C ATOM 1013 C TYR A 140 -2.413 1.656 -29.068 1.00 72.96 C ATOM 1014 O TYR A 140 -1.748 2.041 -30.043 1.00 76.21 O ATOM 1015 CB TYR A 140 -3.498 -0.592 -28.804 1.00 70.97 C ATOM 1016 CG TYR A 140 -3.854 -0.660 -30.248 1.00 71.60 C ATOM 1017 CD1 TYR A 140 -4.711 0.255 -30.820 1.00 70.30 C ATOM 1018 CD2 TYR A 140 -3.357 -1.680 -31.036 1.00 80.12 C ATOM 1019 CE1 TYR A 140 -5.048 0.165 -32.172 1.00 72.62 C ATOM 1020 CE2 TYR A 140 -3.690 -1.783 -32.354 1.00 75.67 C ATOM 1021 CZ TYR A 140 -4.519 -0.873 -32.920 1.00 67.29 C ATOM 1022 OH TYR A 140 -4.822 -1.067 -34.227 1.00 70.25 O ATOM 1023 N ILE A 141 -3.314 2.447 -28.474 1.00 69.77 N ATOM 1024 CA ILE A 141 -3.595 3.781 -29.008 1.00 69.16 C ATOM 1025 C ILE A 141 -2.365 4.666 -28.898 1.00 68.69 C ATOM 1026 O ILE A 141 -1.946 5.303 -29.874 1.00 70.40 O ATOM 1027 CB ILE A 141 -4.801 4.402 -28.285 1.00 71.90 C ATOM 1028 CG1 ILE A 141 -6.090 3.780 -28.826 1.00 70.91 C ATOM 1029 CG2 ILE A 141 -4.819 5.964 -28.423 1.00 73.59 C ATOM 1030 N HIS A 142 -1.770 4.720 -27.697 1.00 72.29 N ATOM 1031 CA HIS A 142 -0.581 5.539 -27.471 1.00 72.56 C ATOM 1032 C HIS A 142 0.545 5.178 -28.424 1.00 78.32 C ATOM 1033 O HIS A 142 1.369 6.026 -28.774 1.00 83.11 O ATOM 1034 CB HIS A 142 -0.102 5.363 -26.044 1.00 75.98 C ATOM 1035 CG HIS A 142 -0.966 6.059 -25.048 1.00 73.97 C ATOM 1036 ND1 HIS A 142 -0.810 5.910 -23.689 1.00 76.57 N ATOM 1037 CD2 HIS A 142 -2.004 6.912 -25.220 1.00 70.14 C ATOM 1038 CE1 HIS A 142 -1.713 6.649 -23.066 1.00 80.18 C ATOM 1039 NE2 HIS A 142 -2.449 7.268 -23.973 1.00 72.18 N ATOM 1040 N SER A 143 0.588 3.925 -28.854 1.00 73.52 N ATOM 1041 CA SER A 143 1.677 3.423 -29.669 1.00 72.50 C ATOM 1042 C SER A 143 1.612 3.919 -31.098 1.00 80.46 C ATOM 1043 O SER A 143 2.592 3.775 -31.836 1.00 80.24 O ATOM 1044 CB SER A 143 1.592 1.959 -29.740 1.00 76.44 C ATOM 1045 OG SER A 143 0.581 1.690 -30.702 1.00 73.96 O ATOM 1046 N ALA A 144 0.455 4.435 -31.513 1.00 75.99 N ATOM 1047 CA ALA A 144 0.257 5.104 -32.781 1.00 66.52 C ATOM 1048 C ALA A 144 0.343 6.624 -32.647 1.00 76.48 C ATOM 1049 O ALA A 144 -0.133 7.361 -33.533 1.00 66.24 O ATOM 1050 CB ALA A 144 -1.095 4.693 -33.355 1.00 66.43 C ATOM 1051 N ASP A 145 0.891 7.111 -31.530 1.00 75.16 N ATOM 1052 CA ASP A 145 1.027 8.546 -31.288 1.00 75.64 C ATOM 1053 C ASP A 145 -0.322 9.240 -31.169 1.00 71.01 C ATOM 1054 O ASP A 145 -0.422 10.452 -31.409 1.00 65.94 O ATOM 1055 CB ASP A 145 1.877 9.226 -32.381 1.00 77.31 C ATOM 1056 N ILE A 146 -1.365 8.502 -30.801 1.00 70.84 N ATOM 1057 CA ILE A 146 -2.681 9.077 -30.548 1.00 69.28 C ATOM 1058 C ILE A 146 -2.881 9.162 -29.034 1.00 71.02 C ATOM 1059 O ILE A 146 -2.608 8.193 -28.305 1.00 70.04 O ATOM 1060 CB ILE A 146 -3.805 8.240 -31.180 1.00 70.59 C ATOM 1061 CG1 ILE A 146 -3.505 7.859 -32.643 1.00 70.70 C ATOM 1062 CG2 ILE A 146 -5.108 9.014 -31.107 1.00 67.56 C ATOM 1063 CD1 ILE A 146 -3.078 8.999 -33.537 1.00 75.19 C ATOM 1064 N ILE A 147 -3.334 10.322 -28.560 1.00 67.74 N ATOM 1065 CA ILE A 147 -3.744 10.519 -27.178 1.00 65.41 C ATOM 1066 C ILE A 147 -5.260 10.559 -27.122 1.00 67.41 C ATOM 1067 O ILE A 147 -5.896 11.301 -27.878 1.00 71.83 O ATOM 1068 CB ILE A 147 -3.173 11.806 -26.561 1.00 73.11 C ATOM 1069 CG1 ILE A 147 -1.656 11.748 -26.441 1.00 79.10 C ATOM 1070 CG2 ILE A 147 -3.731 11.946 -25.156 1.00 71.56 C ATOM 1071 N HIS A 148 -5.838 9.813 -26.187 1.00 64.08 N ATOM 1072 CA HIS A 148 -7.257 9.997 -25.948 1.00 60.76 C ATOM 1073 C HIS A 148 -7.524 11.445 -25.563 1.00 64.06 C ATOM 1074 O HIS A 148 -8.179 12.184 -26.314 1.00 66.45 O ATOM 1075 CB HIS A 148 -7.784 9.042 -24.867 1.00 53.82 C ATOM 1076 CG HIS A 148 -9.270 8.959 -24.878 1.00 53.81 C ATOM 1077 ND1 HIS A 148 -10.069 10.027 -24.544 1.00 55.17 N ATOM 1078 CD2 HIS A 148 -10.104 7.994 -25.331 1.00 59.59 C ATOM 1079 CE1 HIS A 148 -11.336 9.703 -24.747 1.00 58.87 C ATOM 1080 NE2 HIS A 148 -11.385 8.469 -25.219 1.00 57.43 N ATOM 1081 N ARG A 149 -7.017 11.832 -24.392 1.00 58.41 N ATOM 1082 CA ARG A 149 -7.055 13.153 -23.742 1.00 69.71 C ATOM 1083 C ARG A 149 -8.428 13.566 -23.211 1.00 61.28 C ATOM 1084 O ARG A 149 -8.531 14.623 -22.603 1.00 67.81 O ATOM 1085 CB ARG A 149 -6.463 14.276 -24.633 1.00 66.60 C ATOM 1086 CG ARG A 149 -7.391 14.936 -25.587 1.00 67.39 C ATOM 1087 CD ARG A 149 -6.619 16.023 -26.339 1.00 81.15 C ATOM 1088 NE ARG A 149 -5.679 15.483 -27.310 1.00 81.97 N ATOM 1089 CZ ARG A 149 -4.381 15.777 -27.340 1.00 82.06 C ATOM 1090 NH1 ARG A 149 -3.873 16.619 -26.449 1.00 75.96 N ATOM 1091 NH2 ARG A 149 -3.596 15.236 -28.273 1.00 84.36 N ATOM 1092 N ASP A 150 -9.469 12.773 -23.394 1.00 57.52 N ATOM 1093 CA ASP A 150 -10.720 13.058 -22.696 1.00 56.23 C ATOM 1094 C ASP A 150 -11.253 11.798 -22.016 1.00 55.48 C ATOM 1095 O ASP A 150 -12.464 11.564 -21.948 1.00 54.98 O ATOM 1096 CB ASP A 150 -11.778 13.637 -23.638 1.00 55.24 C ATOM 1097 CG ASP A 150 -12.921 14.331 -22.898 1.00 59.65 C ATOM 1098 OD1 ASP A 150 -12.735 14.773 -21.747 1.00 65.90 O ATOM 1099 OD2 ASP A 150 -14.038 14.397 -23.447 1.00 73.30 O ATOM 1100 N LEU A 151 -10.357 10.961 -21.535 1.00 56.42 N ATOM 1101 CA LEU A 151 -10.767 9.641 -21.082 1.00 56.05 C ATOM 1102 C LEU A 151 -11.625 9.766 -19.821 1.00 60.72 C ATOM 1103 O LEU A 151 -11.246 10.418 -18.847 1.00 55.07 O ATOM 1104 CB LEU A 151 -9.548 8.773 -20.814 1.00 52.41 C ATOM 1105 CG LEU A 151 -9.786 7.278 -20.823 1.00 62.55 C ATOM 1106 CD1 LEU A 151 -10.319 6.763 -22.231 1.00 54.67 C ATOM 1107 CD2 LEU A 151 -8.498 6.566 -20.425 1.00 59.19 C ATOM 1108 N LYS A 152 -12.808 9.173 -19.863 1.00 59.24 N ATOM 1109 CA LYS A 152 -13.757 9.328 -18.779 1.00 63.28 C ATOM 1110 C LYS A 152 -14.729 8.169 -18.833 1.00 63.15 C ATOM 1111 O LYS A 152 -14.850 7.514 -19.854 1.00 60.35 O ATOM 1112 CB LYS A 152 -14.478 10.669 -18.873 1.00 57.76 C ATOM 1113 CG LYS A 152 -15.261 10.829 -20.191 1.00 59.77 C ATOM 1114 CD LYS A 152 -15.927 12.212 -20.185 1.00 60.47 C ATOM 1115 CE LYS A 152 -16.169 12.701 -21.550 1.00 64.41 C ATOM 1116 NZ LYS A 152 -16.719 14.087 -21.419 1.00 80.72 N ATOM 1117 N PRO A 153 -15.457 7.917 -17.755 1.00 66.27 N ATOM 1118 CA PRO A 153 -16.269 6.694 -17.720 1.00 59.64 C ATOM 1119 C PRO A 153 -17.280 6.573 -18.849 1.00 56.33 C ATOM 1120 O PRO A 153 -17.628 5.445 -19.229 1.00 56.66 O ATOM 1121 CB PRO A 153 -16.950 6.778 -16.343 1.00 56.94 C ATOM 1122 CG PRO A 153 -15.866 7.483 -15.483 1.00 61.64 C ATOM 1123 CD PRO A 153 -15.356 8.572 -16.427 1.00 53.13 C ATOM 1124 N SER A 154 -17.783 7.681 -19.384 1.00 52.12 N ATOM 1125 CA SER A 154 -18.809 7.567 -20.413 1.00 54.43 C ATOM 1126 C SER A 154 -18.208 7.224 -21.772 1.00 60.08 C ATOM 1127 O SER A 154 -18.950 7.010 -22.740 1.00 52.40 O ATOM 1128 CB SER A 154 -19.590 8.873 -20.509 1.00 60.95 C ATOM 1129 OG SER A 154 -18.738 9.942 -20.900 1.00 63.62 O ATOM 1130 N ASN A 155 -16.879 7.206 -21.853 1.00 62.73 N ATOM 1131 CA ASN A 155 -16.118 6.849 -23.038 1.00 67.55 C ATOM 1132 C ASN A 155 -15.654 5.398 -22.991 1.00 57.81 C ATOM 1133 O ASN A 155 -14.751 5.001 -23.745 1.00 53.54 O ATOM 1134 CB ASN A 155 -14.882 7.764 -23.187 1.00 60.58 C ATOM 1135 CG ASN A 155 -15.221 9.163 -23.602 1.00 61.33 C ATOM 1136 OD1 ASN A 155 -16.285 9.424 -24.170 1.00 71.44 O ATOM 1137 ND2 ASN A 155 -14.270 10.074 -23.411 1.00 62.26 N ATOM 1138 N LEU A 156 -16.196 4.612 -22.097 1.00 53.11 N ATOM 1139 CA LEU A 156 -15.748 3.240 -21.970 1.00 54.45 C ATOM 1140 C LEU A 156 -16.987 2.373 -22.131 1.00 53.06 C ATOM 1141 O LEU A 156 -17.915 2.457 -21.318 1.00 55.39 O ATOM 1142 CB LEU A 156 -15.021 3.051 -20.641 1.00 65.75 C ATOM 1143 CG LEU A 156 -13.793 3.976 -20.526 1.00 58.12 C ATOM 1144 CD1 LEU A 156 -13.265 3.921 -19.168 1.00 66.72 C ATOM 1145 CD2 LEU A 156 -12.741 3.481 -21.475 1.00 59.18 C ATOM 1146 N ALA A 157 -17.034 1.584 -23.204 1.00 45.56 N ATOM 1147 CA ALA A 157 -18.224 0.791 -23.470 1.00 52.59 C ATOM 1148 C ALA A 157 -18.035 -0.625 -22.920 1.00 51.26 C ATOM 1149 O ALA A 157 -16.936 -1.198 -22.983 1.00 46.96 O ATOM 1150 CB ALA A 157 -18.505 0.763 -24.981 1.00 62.82 C ATOM 1151 N VAL A 158 -19.089 -1.187 -22.357 1.00 48.79 N ATOM 1152 CA VAL A 158 -18.925 -2.497 -21.756 1.00 57.91 C ATOM 1153 C VAL A 158 -20.094 -3.384 -22.112 1.00 59.19 C ATOM 1154 O VAL A 158 -21.201 -2.927 -22.408 1.00 54.26 O ATOM 1155 CB VAL A 158 -18.761 -2.463 -20.216 1.00 53.70 C ATOM 1156 CG1 VAL A 158 -17.443 -1.857 -19.847 1.00 56.41 C ATOM 1157 CG2 VAL A 158 -19.909 -1.713 -19.598 1.00 52.26 C ATOM 1158 N ASN A 159 -19.817 -4.675 -22.020 1.00 66.75 N ATOM 1159 CA ASN A 159 -20.735 -5.758 -22.309 1.00 67.82 C ATOM 1160 C ASN A 159 -21.164 -6.424 -21.013 1.00 73.70 C ATOM 1161 O ASN A 159 -20.560 -6.240 -19.951 1.00 64.11 O ATOM 1162 CB ASN A 159 -20.063 -6.808 -23.196 1.00 67.79 C ATOM 1163 CG ASN A 159 -19.983 -6.397 -24.638 1.00 80.90 C ATOM 1164 OD1 ASN A 159 -20.699 -5.473 -25.104 1.00 73.82 O ATOM 1165 ND2 ASN A 159 -19.105 -7.079 -25.377 1.00 80.93 N ATOM 1166 N GLU A 160 -22.195 -7.263 -21.157 1.00 83.41 N ATOM 1167 CA GLU A 160 -22.615 -8.194 -20.120 1.00 75.06 C ATOM 1168 C GLU A 160 -21.501 -9.144 -19.717 1.00 78.80 C ATOM 1169 O GLU A 160 -21.539 -9.698 -18.614 1.00 84.75 O ATOM 1170 CB GLU A 160 -23.818 -8.990 -20.609 1.00 84.60 C ATOM 1171 N ASP A 161 -20.506 -9.347 -20.573 1.00 74.73 N ATOM 1172 CA ASP A 161 -19.402 -10.240 -20.260 1.00 76.69 C ATOM 1173 C ASP A 161 -18.186 -9.515 -19.695 1.00 70.97 C ATOM 1174 O ASP A 161 -17.080 -10.070 -19.728 1.00 67.27 O ATOM 1175 CB ASP A 161 -19.027 -11.047 -21.505 1.00 76.87 C ATOM 1176 CG ASP A 161 -20.227 -11.779 -22.093 1.00 92.60 C ATOM 1177 OD1 ASP A 161 -21.362 -11.485 -21.651 1.00 95.53 O ATOM 1178 OD2 ASP A 161 -20.044 -12.639 -22.988 1.00 97.06 O ATOM 1179 N CYS A 162 -18.358 -8.280 -19.205 1.00 76.35 N ATOM 1180 CA CYS A 162 -17.291 -7.454 -18.625 1.00 74.12 C ATOM 1181 C CYS A 162 -16.251 -7.010 -19.649 1.00 68.09 C ATOM 1182 O CYS A 162 -15.178 -6.543 -19.271 1.00 65.26 O ATOM 1183 CB CYS A 162 -16.600 -8.191 -17.453 1.00 79.27 C ATOM 1184 SG CYS A 162 -15.860 -7.167 -16.162 1.00 79.63 S ATOM 1185 N GLU A 163 -16.537 -7.138 -20.944 1.00 69.03 N ATOM 1186 CA GLU A 163 -15.600 -6.710 -21.979 1.00 67.29 C ATOM 1187 C GLU A 163 -15.708 -5.205 -22.190 1.00 60.04 C ATOM 1188 O GLU A 163 -16.814 -4.669 -22.261 1.00 58.86 O ATOM 1189 CB GLU A 163 -15.864 -7.459 -23.284 1.00 75.75 C ATOM 1190 CG GLU A 163 -15.652 -8.943 -23.124 1.00 81.49 C ATOM 1191 CD GLU A 163 -16.050 -9.732 -24.338 1.00 87.09 C ATOM 1192 OE1 GLU A 163 -15.272 -10.626 -24.720 1.00 93.59 O ATOM 1193 OE2 GLU A 163 -17.131 -9.462 -24.904 1.00 91.79 O ATOM 1194 N LEU A 164 -14.556 -4.524 -22.284 1.00 60.02 N ATOM 1195 CA LEU A 164 -14.502 -3.061 -22.360 1.00 62.96 C ATOM 1196 C LEU A 164 -13.915 -2.567 -23.681 1.00 58.27 C ATOM 1197 O LEU A 164 -12.935 -3.133 -24.177 1.00 61.77 O ATOM 1198 CB LEU A 164 -13.664 -2.465 -21.227 1.00 61.07 C ATOM 1199 CG LEU A 164 -13.416 -0.932 -21.267 1.00 60.25 C ATOM 1200 CD1 LEU A 164 -13.346 -0.439 -19.817 1.00 60.68 C ATOM 1201 CD2 LEU A 164 -12.179 -0.408 -22.073 1.00 50.21 C ATOM 1202 N LYS A 165 -14.466 -1.466 -24.212 1.00 52.53 N ATOM 1203 CA LYS A 165 -13.906 -0.793 -25.391 1.00 57.91 C ATOM 1204 C LYS A 165 -13.766 0.721 -25.185 1.00 55.70 C ATOM 1205 O LYS A 165 -14.670 1.379 -24.661 1.00 54.38 O ATOM 1206 CB LYS A 165 -14.750 -1.077 -26.644 1.00 52.78 C ATOM 1207 CG LYS A 165 -14.495 -2.478 -27.190 1.00 60.73 C ATOM 1208 CD LYS A 165 -15.446 -2.911 -28.293 1.00 58.60 C ATOM 1209 CE LYS A 165 -15.307 -4.399 -28.609 1.00 60.11 C ATOM 1210 NZ LYS A 165 -16.071 -4.751 -29.843 1.00 74.75 N ATOM 1211 N ILE A 166 -12.624 1.266 -25.578 1.00 50.79 N ATOM 1212 CA ILE A 166 -12.457 2.704 -25.528 1.00 53.38 C ATOM 1213 C ILE A 166 -13.125 3.311 -26.734 1.00 57.37 C ATOM 1214 O ILE A 166 -13.031 2.785 -27.859 1.00 59.75 O ATOM 1215 CB ILE A 166 -10.988 3.113 -25.522 1.00 54.58 C ATOM 1216 CG1 ILE A 166 -10.220 2.326 -24.458 1.00 48.54 C ATOM 1217 CG2 ILE A 166 -10.897 4.660 -25.355 1.00 44.31 C ATOM 1218 CD1 ILE A 166 -8.754 2.628 -24.459 1.00 51.64 C ATOM 1219 N LEU A 167 -13.798 4.432 -26.528 1.00 57.56 N ATOM 1220 CA LEU A 167 -14.212 5.165 -27.711 1.00 58.57 C ATOM 1221 C LEU A 167 -14.012 6.656 -27.502 1.00 55.82 C ATOM 1222 O LEU A 167 -13.669 7.123 -26.403 1.00 51.36 O ATOM 1223 CB LEU A 167 -15.641 4.835 -28.108 1.00 56.42 C ATOM 1224 CG LEU A 167 -16.894 5.142 -27.338 1.00 60.73 C ATOM 1225 CD1 LEU A 167 -18.003 5.171 -28.376 1.00 73.29 C ATOM 1226 CD2 LEU A 167 -17.187 4.059 -26.349 1.00 64.55 C ATOM 1227 N ASP A 168 -14.148 7.380 -28.616 1.00 56.67 N ATOM 1228 CA ASP A 168 -14.039 8.834 -28.681 1.00 61.25 C ATOM 1229 C ASP A 168 -12.610 9.335 -28.450 1.00 60.50 C ATOM 1230 O ASP A 168 -12.394 10.515 -28.156 1.00 61.60 O ATOM 1231 CB ASP A 168 -15.056 9.499 -27.740 1.00 56.66 C ATOM 1232 CG ASP A 168 -16.488 9.416 -28.293 1.00 63.30 C ATOM 1233 OD1 ASP A 168 -16.609 9.134 -29.522 1.00 64.21 O ATOM 1234 OD2 ASP A 168 -17.480 9.621 -27.534 1.00 54.93 O ATOM 1235 N PHE A 169 -11.632 8.446 -28.626 1.00 62.88 N ATOM 1236 CA PHE A 169 -10.219 8.789 -28.504 1.00 61.61 C ATOM 1237 C PHE A 169 -9.768 9.645 -29.676 1.00 58.85 C ATOM 1238 O PHE A 169 -10.255 9.482 -30.798 1.00 60.41 O ATOM 1239 CB PHE A 169 -9.357 7.536 -28.495 1.00 56.95 C ATOM 1240 CG PHE A 169 -9.769 6.567 -29.530 1.00 56.33 C ATOM 1241 CD1 PHE A 169 -10.688 5.578 -29.245 1.00 59.83 C ATOM 1242 CD2 PHE A 169 -9.320 6.709 -30.820 1.00 66.35 C ATOM 1243 CE1 PHE A 169 -11.110 4.689 -30.234 1.00 61.82 C ATOM 1244 CE2 PHE A 169 -9.733 5.837 -31.821 1.00 68.39 C ATOM 1245 CZ PHE A 169 -10.627 4.819 -31.517 1.00 67.99 C ATOM 1246 N GLY A 170 -8.770 10.494 -29.418 1.00 59.23 N ATOM 1247 CA GLY A 170 -8.089 11.280 -30.401 1.00 60.03 C ATOM 1248 C GLY A 170 -8.950 12.333 -31.048 1.00 67.52 C ATOM 1249 O GLY A 170 -8.535 12.930 -32.056 1.00 66.69 O ATOM 1250 N LEU A 171 -10.147 12.567 -30.518 1.00 61.05 N ATOM 1251 CA LEU A 171 -11.046 13.524 -31.136 1.00 67.39 C ATOM 1252 C LEU A 171 -10.989 14.893 -30.471 1.00 69.10 C ATOM 1253 O LEU A 171 -11.395 15.876 -31.091 1.00 72.38 O ATOM 1254 CB LEU A 171 -12.495 13.003 -31.122 1.00 64.11 C ATOM 1255 CG LEU A 171 -12.819 11.639 -31.731 1.00 61.37 C ATOM 1256 CD1 LEU A 171 -14.320 11.341 -31.777 1.00 61.06 C ATOM 1257 CD2 LEU A 171 -12.272 11.578 -33.111 1.00 70.25 C ATOM 1258 N ALA A 172 -10.498 14.983 -29.239 1.00 71.13 N ATOM 1259 CA ALA A 172 -10.561 16.240 -28.492 1.00 72.87 C ATOM 1260 C ALA A 172 -9.474 17.209 -28.890 1.00 75.23 C ATOM 1261 O ALA A 172 -8.417 17.197 -28.276 1.00 74.81 O ATOM 1262 CB ALA A 172 -10.470 15.969 -27.016 1.00 71.55 C ATOM 1263 N TYR A 182 -19.397 18.429 -20.853 1.00 96.79 N ATOM 1264 CA TYR A 182 -18.142 19.099 -20.522 1.00 96.99 C ATOM 1265 C TYR A 182 -17.887 19.142 -19.035 1.00 92.20 C ATOM 1266 O TYR A 182 -16.740 19.103 -18.576 1.00 88.54 O ATOM 1267 CB TYR A 182 -18.143 20.533 -21.048 1.00 97.83 C ATOM 1268 CG TYR A 182 -17.067 21.413 -20.446 1.00 87.73 C ATOM 1269 CD1 TYR A 182 -15.781 21.422 -20.971 1.00 94.86 C ATOM 1270 CD2 TYR A 182 -17.341 22.246 -19.368 1.00 89.23 C ATOM 1271 CE1 TYR A 182 -14.790 22.240 -20.436 1.00 93.04 C ATOM 1272 CE2 TYR A 182 -16.354 23.063 -18.818 1.00 92.14 C ATOM 1273 CZ TYR A 182 -15.083 23.057 -19.363 1.00 93.28 C ATOM 1274 OH TYR A 182 -14.104 23.866 -18.828 1.00 96.95 O ATOM 1275 N VAL A 183 -18.971 19.294 -18.279 1.00 98.32 N ATOM 1276 CA VAL A 183 -18.825 19.501 -16.845 1.00 93.19 C ATOM 1277 C VAL A 183 -18.247 18.255 -16.204 1.00 88.72 C ATOM 1278 O VAL A 183 -17.278 18.325 -15.435 1.00 89.80 O ATOM 1279 CB VAL A 183 -20.172 19.901 -16.212 1.00 96.45 C ATOM 1280 N ALA A 184 -18.814 17.092 -16.542 1.00 92.70 N ATOM 1281 CA ALA A 184 -18.314 15.840 -15.992 1.00 84.26 C ATOM 1282 C ALA A 184 -16.852 15.631 -16.364 1.00 81.49 C ATOM 1283 O ALA A 184 -16.036 15.263 -15.507 1.00 82.62 O ATOM 1284 CB ALA A 184 -19.177 14.677 -16.479 1.00 82.95 C ATOM 1285 N GLY A 185 -16.493 15.932 -17.620 1.00 78.56 N ATOM 1286 CA GLY A 185 -15.155 15.647 -18.109 1.00 69.15 C ATOM 1287 C GLY A 185 -14.051 16.327 -17.329 1.00 72.58 C ATOM 1288 O GLY A 185 -12.908 15.855 -17.335 1.00 69.19 O ATOM 1289 N ARG A 186 -14.358 17.441 -16.656 1.00 72.51 N ATOM 1290 CA ARG A 186 -13.346 18.105 -15.848 1.00 73.07 C ATOM 1291 C ARG A 186 -12.780 17.190 -14.770 1.00 69.61 C ATOM 1292 O ARG A 186 -11.622 17.353 -14.377 1.00 67.49 O ATOM 1293 CB ARG A 186 -13.941 19.361 -15.177 1.00 83.64 C ATOM 1294 CG ARG A 186 -12.900 20.141 -14.355 1.00 82.76 C ATOM 1295 CD ARG A 186 -13.457 21.285 -13.486 1.00 98.42 C ATOM 1296 NE ARG A 186 -14.168 22.310 -14.237 1.00 95.10 N ATOM 1297 CZ ARG A 186 -15.492 22.405 -14.270 1.00 99.20 C ATOM 1298 NH1 ARG A 186 -16.244 21.544 -13.586 1.00100.02 N ATOM 1299 NH2 ARG A 186 -16.061 23.374 -14.978 1.00 95.99 N ATOM 1300 N TRP A 187 -13.554 16.208 -14.299 1.00 67.97 N ATOM 1301 CA TRP A 187 -13.086 15.451 -13.139 1.00 71.30 C ATOM 1302 C TRP A 187 -11.888 14.570 -13.451 1.00 66.77 C ATOM 1303 O TRP A 187 -11.083 14.279 -12.553 1.00 71.22 O ATOM 1304 CB TRP A 187 -14.218 14.607 -12.544 1.00 72.16 C ATOM 1305 CG TRP A 187 -15.310 15.476 -12.008 1.00 76.87 C ATOM 1306 CD1 TRP A 187 -15.174 16.740 -11.493 1.00 79.90 C ATOM 1307 CD2 TRP A 187 -16.713 15.195 -12.009 1.00 81.39 C ATOM 1308 NE1 TRP A 187 -16.404 17.249 -11.157 1.00 81.79 N ATOM 1309 CE2 TRP A 187 -17.368 16.327 -11.469 1.00 79.75 C ATOM 1310 CE3 TRP A 187 -17.480 14.090 -12.392 1.00 77.38 C ATOM 1311 CZ2 TRP A 187 -18.753 16.384 -11.308 1.00 80.08 C ATOM 1312 CZ3 TRP A 187 -18.865 14.146 -12.233 1.00 78.96 C ATOM 1313 CH2 TRP A 187 -19.483 15.284 -11.697 1.00 86.74 C ATOM 1314 N TYR A 188 -11.720 14.158 -14.691 1.00 66.48 N ATOM 1315 CA TYR A 188 -10.715 13.154 -14.996 1.00 71.67 C ATOM 1316 C TYR A 188 -9.545 13.739 -15.741 1.00 72.79 C ATOM 1317 O TYR A 188 -8.668 12.989 -16.184 1.00 75.83 O ATOM 1318 CB TYR A 188 -11.337 11.995 -15.803 1.00 62.65 C ATOM 1319 CG TYR A 188 -12.599 11.500 -15.146 1.00 60.98 C ATOM 1320 CD1 TYR A 188 -12.573 10.493 -14.192 1.00 58.93 C ATOM 1321 CD2 TYR A 188 -13.802 12.123 -15.406 1.00 64.97 C ATOM 1322 CE1 TYR A 188 -13.731 10.077 -13.579 1.00 61.07 C ATOM 1323 CE2 TYR A 188 -14.941 11.727 -14.798 1.00 60.23 C ATOM 1324 CZ TYR A 188 -14.919 10.713 -13.901 1.00 61.33 C ATOM 1325 OH TYR A 188 -16.134 10.401 -13.343 1.00 67.07 O ATOM 1326 N ARG A 189 -9.511 15.055 -15.895 1.00 71.95 N ATOM 1327 CA ARG A 189 -8.477 15.654 -16.703 1.00 78.39 C ATOM 1328 C ARG A 189 -7.219 15.802 -15.879 1.00 71.39 C ATOM 1329 O ARG A 189 -7.267 16.130 -14.701 1.00 69.21 O ATOM 1330 CB ARG A 189 -8.911 16.996 -17.273 1.00 84.83 C ATOM 1331 CG ARG A 189 -10.255 16.956 -17.926 1.00 85.47 C ATOM 1332 CD ARG A 189 -10.460 18.187 -18.771 1.00 81.46 C ATOM 1333 NE ARG A 189 -9.689 18.124 -20.005 1.00 86.43 N ATOM 1334 CZ ARG A 189 -10.235 17.904 -21.198 1.00 92.07 C ATOM 1335 NH1 ARG A 189 -9.496 17.883 -22.316 1.00 83.78 N ATOM 1336 NH2 ARG A 189 -11.542 17.687 -21.261 1.00 87.25 N ATOM 1337 N ALA A 190 -6.096 15.481 -16.497 1.00 81.61 N ATOM 1338 CA ALA A 190 -4.820 15.729 -15.863 1.00 82.94 C ATOM 1339 C ALA A 190 -4.701 17.219 -15.551 1.00 87.15 C ATOM 1340 O ALA A 190 -5.234 18.053 -16.293 1.00 89.02 O ATOM 1341 CB ALA A 190 -3.684 15.259 -16.774 1.00 84.24 C ATOM 1342 N PRO A 191 -4.045 17.588 -14.449 1.00 89.28 N ATOM 1343 CA PRO A 191 -4.025 19.009 -14.064 1.00 88.52 C ATOM 1344 C PRO A 191 -3.306 19.897 -15.065 1.00 94.27 C ATOM 1345 O PRO A 191 -3.823 20.967 -15.416 1.00 97.34 O ATOM 1346 CB PRO A 191 -3.314 18.976 -12.699 1.00 90.19 C ATOM 1347 CG PRO A 191 -2.489 17.704 -12.727 1.00 88.36 C ATOM 1348 CD PRO A 191 -3.362 16.733 -13.455 1.00 86.69 C ATOM 1349 N GLU A 192 -2.136 19.470 -15.553 1.00 93.79 N ATOM 1350 CA GLU A 192 -1.400 20.265 -16.530 1.00 98.63 C ATOM 1351 C GLU A 192 -2.216 20.590 -17.775 1.00101.62 C ATOM 1352 O GLU A 192 -1.939 21.598 -18.430 1.00107.13 O ATOM 1353 CB GLU A 192 -0.110 19.562 -16.941 1.00 94.18 C ATOM 1354 CG GLU A 192 -0.320 18.234 -17.610 1.00 92.58 C ATOM 1355 CD GLU A 192 -0.306 17.096 -16.613 1.00 96.21 C ATOM 1356 OE1 GLU A 192 0.021 15.967 -17.030 1.00 87.80 O ATOM 1357 OE2 GLU A 192 -0.617 17.337 -15.411 1.00 94.53 O ATOM 1358 N ILE A 193 -3.206 19.774 -18.123 1.00 99.84 N ATOM 1359 CA ILE A 193 -4.055 20.071 -19.277 1.00100.17 C ATOM 1360 C ILE A 193 -5.171 21.037 -18.908 1.00102.25 C ATOM 1361 O ILE A 193 -5.397 22.026 -19.606 1.00109.04 O ATOM 1362 CB ILE A 193 -4.626 18.771 -19.886 1.00 95.77 C ATOM 1363 CG1 ILE A 193 -3.505 17.865 -20.373 1.00 90.67 C ATOM 1364 CG2 ILE A 193 -5.578 19.096 -21.035 1.00100.68 C ATOM 1365 N MET A 194 -5.899 20.751 -17.827 1.00103.52 N ATOM 1366 CA MET A 194 -6.975 21.632 -17.388 1.00104.84 C ATOM 1367 C MET A 194 -6.508 23.078 -17.354 1.00111.06 C ATOM 1368 O MET A 194 -7.163 23.973 -17.902 1.00113.39 O ATOM 1369 CB MET A 194 -7.474 21.201 -16.003 1.00103.17 C ATOM 1370 N LEU A 195 -5.339 23.310 -16.754 1.00112.33 N ATOM 1371 CA LEU A 195 -4.815 24.649 -16.528 1.00114.39 C ATOM 1372 C LEU A 195 -3.607 24.986 -17.400 1.00116.05 C ATOM 1373 O LEU A 195 -2.815 25.853 -17.022 1.00123.50 O ATOM 1374 CB LEU A 195 -4.463 24.831 -15.054 1.00112.59 C ATOM 1375 N ASN A 196 -3.439 24.317 -18.544 1.00117.39 N ATOM 1376 CA ASN A 196 -2.412 24.662 -19.551 1.00119.64 C ATOM 1377 C ASN A 196 -1.003 24.826 -18.956 1.00120.46 C ATOM 1378 O ASN A 196 -0.324 25.825 -19.204 1.00124.87 O ATOM 1379 CB ASN A 196 -2.804 25.943 -20.315 1.00120.29 C ATOM 1380 CG ASN A 196 -4.201 25.883 -20.929 1.00119.71 C ATOM 1381 OD1 ASN A 196 -5.199 25.658 -20.243 1.00118.47 O ATOM 1382 ND2 ASN A 196 -4.273 26.123 -22.234 1.00118.34 N ATOM 1383 N TRP A 197 -0.535 23.819 -18.199 1.00116.65 N ATOM 1384 CA TRP A 197 0.754 23.940 -17.504 1.00113.74 C ATOM 1385 C TRP A 197 1.964 23.631 -18.363 1.00115.42 C ATOM 1386 O TRP A 197 3.037 24.195 -18.133 1.00117.07 O ATOM 1387 CB TRP A 197 0.847 22.983 -16.330 1.00113.97 C ATOM 1388 CG TRP A 197 0.021 23.331 -15.200 1.00113.40 C ATOM 1389 CD1 TRP A 197 -0.830 24.390 -15.091 1.00114.02 C ATOM 1390 CD2 TRP A 197 -0.047 22.620 -13.974 1.00107.32 C ATOM 1391 NE1 TRP A 197 -1.439 24.371 -13.861 1.00114.52 N ATOM 1392 CE2 TRP A 197 -0.973 23.290 -13.158 1.00107.66 C ATOM 1393 CE3 TRP A 197 0.581 21.472 -13.490 1.00100.54 C ATOM 1394 CZ2 TRP A 197 -1.285 22.852 -11.890 1.00104.74 C ATOM 1395 CZ3 TRP A 197 0.274 21.040 -12.236 1.00102.38 C ATOM 1396 CH2 TRP A 197 -0.651 21.726 -11.445 1.00105.62 C ATOM 1397 N MET A 198 1.851 22.658 -19.255 1.00120.83 N ATOM 1398 CA MET A 198 2.949 22.251 -20.114 1.00125.97 C ATOM 1399 C MET A 198 2.362 21.820 -21.449 1.00124.60 C ATOM 1400 O MET A 198 1.159 21.937 -21.684 1.00123.54 O ATOM 1401 CB MET A 198 3.778 21.111 -19.485 1.00118.74 C ATOM 1402 CG MET A 198 3.659 20.959 -17.984 1.00113.70 C ATOM 1403 N HIS A 199 3.229 21.329 -22.331 1.00126.91 N ATOM 1404 CA HIS A 199 2.772 20.545 -23.471 1.00128.33 C ATOM 1405 C HIS A 199 2.386 19.148 -22.996 1.00124.47 C ATOM 1406 O HIS A 199 3.164 18.480 -22.305 1.00125.17 O ATOM 1407 CB HIS A 199 3.852 20.472 -24.550 1.00130.21 C ATOM 1408 CG HIS A 199 5.246 20.383 -24.011 1.00132.20 C ATOM 1409 ND1 HIS A 199 5.967 21.495 -23.636 1.00133.31 N ATOM 1410 CD2 HIS A 199 6.053 19.319 -23.783 1.00134.73 C ATOM 1411 CE1 HIS A 199 7.156 21.121 -23.198 1.00134.06 C ATOM 1412 NE2 HIS A 199 7.234 19.805 -23.277 1.00138.95 N ATOM 1413 N TYR A 200 1.183 18.699 -23.359 1.00116.71 N ATOM 1414 CA TYR A 200 0.659 17.449 -22.819 1.00102.29 C ATOM 1415 C TYR A 200 1.305 16.262 -23.509 1.00101.02 C ATOM 1416 O TYR A 200 1.390 16.224 -24.742 1.00109.47 O ATOM 1417 CB TYR A 200 -0.859 17.387 -22.989 1.00 95.76 C ATOM 1418 N ASN A 201 1.754 15.300 -22.722 1.00 95.87 N ATOM 1419 CA ASN A 201 2.234 14.041 -23.256 1.00 93.95 C ATOM 1420 C ASN A 201 1.173 12.952 -23.059 1.00 91.98 C ATOM 1421 O ASN A 201 0.056 13.220 -22.603 1.00 88.86 O ATOM 1422 CB ASN A 201 3.547 13.668 -22.571 1.00 89.46 C ATOM 1423 CG ASN A 201 3.339 13.269 -21.145 1.00 93.30 C ATOM 1424 OD1 ASN A 201 2.722 14.010 -20.369 1.00100.98 O ATOM 1425 ND2 ASN A 201 3.840 12.096 -20.773 1.00 96.05 N ATOM 1426 N GLN A 202 1.529 11.698 -23.394 1.00 89.59 N ATOM 1427 CA GLN A 202 0.534 10.626 -23.420 1.00 86.86 C ATOM 1428 C GLN A 202 0.026 10.248 -22.034 1.00 82.82 C ATOM 1429 O GLN A 202 -1.121 9.807 -21.914 1.00 80.76 O ATOM 1430 CB GLN A 202 1.093 9.371 -24.096 1.00 83.18 C ATOM 1431 CG GLN A 202 2.148 9.599 -25.130 1.00 86.63 C ATOM 1432 CD GLN A 202 2.558 8.294 -25.781 1.00 90.28 C ATOM 1433 OE1 GLN A 202 3.011 7.377 -25.098 1.00 93.04 O ATOM 1434 NE2 GLN A 202 2.391 8.197 -27.108 1.00 86.13 N ATOM 1435 N THR A 203 0.858 10.374 -20.989 1.00 83.32 N ATOM 1436 CA THR A 203 0.454 10.007 -19.628 1.00 84.58 C ATOM 1437 C THR A 203 -0.762 10.778 -19.136 1.00 84.51 C ATOM 1438 O THR A 203 -1.345 10.397 -18.110 1.00 83.81 O ATOM 1439 CB THR A 203 1.589 10.230 -18.613 1.00 93.91 C ATOM 1440 OG1 THR A 203 2.094 11.571 -18.744 1.00 89.49 O ATOM 1441 CG2 THR A 203 2.726 9.195 -18.774 1.00 93.06 C ATOM 1442 N VAL A 204 -1.126 11.871 -19.809 1.00 79.17 N ATOM 1443 CA VAL A 204 -2.357 12.581 -19.484 1.00 78.34 C ATOM 1444 C VAL A 204 -3.519 11.607 -19.342 1.00 78.82 C ATOM 1445 O VAL A 204 -4.409 11.789 -18.496 1.00 73.98 O ATOM 1446 CB VAL A 204 -2.630 13.649 -20.556 1.00 84.32 C ATOM 1447 CG1 VAL A 204 -4.114 14.026 -20.628 1.00 85.65 C ATOM 1448 CG2 VAL A 204 -1.767 14.852 -20.279 1.00 84.61 C ATOM 1449 N ASP A 205 -3.526 10.552 -20.166 1.00 73.04 N ATOM 1450 CA ASP A 205 -4.610 9.586 -20.112 1.00 68.60 C ATOM 1451 C ASP A 205 -4.495 8.697 -18.898 1.00 65.62 C ATOM 1452 O ASP A 205 -5.512 8.276 -18.351 1.00 67.49 O ATOM 1453 CB ASP A 205 -4.615 8.714 -21.369 1.00 70.36 C ATOM 1454 CG ASP A 205 -5.052 9.453 -22.607 1.00 66.27 C ATOM 1455 OD1 ASP A 205 -4.689 8.951 -23.675 1.00 73.39 O ATOM 1456 OD2 ASP A 205 -5.762 10.487 -22.529 1.00 61.33 O ATOM 1457 N ILE A 206 -3.271 8.365 -18.497 1.00 66.65 N ATOM 1458 CA ILE A 206 -3.083 7.537 -17.313 1.00 72.12 C ATOM 1459 C ILE A 206 -3.645 8.231 -16.070 1.00 72.85 C ATOM 1460 O ILE A 206 -4.215 7.577 -15.191 1.00 74.98 O ATOM 1461 CB ILE A 206 -1.597 7.185 -17.149 1.00 75.68 C ATOM 1462 CG1 ILE A 206 -1.121 6.380 -18.358 1.00 83.43 C ATOM 1463 CG2 ILE A 206 -1.379 6.415 -15.891 1.00 76.72 C ATOM 1464 CD1 ILE A 206 -1.522 4.879 -18.312 1.00 83.97 C ATOM 1465 N TRP A 207 -3.506 9.556 -15.976 1.00 69.52 N ATOM 1466 CA TRP A 207 -4.156 10.287 -14.890 1.00 74.20 C ATOM 1467 C TRP A 207 -5.646 10.009 -14.869 1.00 70.43 C ATOM 1468 O TRP A 207 -6.234 9.736 -13.812 1.00 67.04 O ATOM 1469 CB TRP A 207 -3.913 11.790 -15.025 1.00 71.51 C ATOM 1470 CG TRP A 207 -4.604 12.603 -13.953 1.00 76.73 C ATOM 1471 CD1 TRP A 207 -5.856 13.161 -14.016 1.00 78.05 C ATOM 1472 CD2 TRP A 207 -4.089 12.935 -12.651 1.00 75.76 C ATOM 1473 NE1 TRP A 207 -6.143 13.823 -12.846 1.00 73.67 N ATOM 1474 CE2 TRP A 207 -5.076 13.701 -11.991 1.00 82.18 C ATOM 1475 CE3 TRP A 207 -2.886 12.667 -11.982 1.00 78.58 C ATOM 1476 CZ2 TRP A 207 -4.890 14.211 -10.686 1.00 76.99 C ATOM 1477 CZ3 TRP A 207 -2.709 13.173 -10.694 1.00 83.06 C ATOM 1478 CH2 TRP A 207 -3.708 13.934 -10.067 1.00 77.20 C ATOM 1479 N SER A 208 -6.271 10.086 -16.041 1.00 67.83 N ATOM 1480 CA SER A 208 -7.681 9.753 -16.160 1.00 69.22 C ATOM 1481 C SER A 208 -7.925 8.312 -15.760 1.00 64.01 C ATOM 1482 O SER A 208 -8.928 8.000 -15.103 1.00 63.79 O ATOM 1483 CB SER A 208 -8.144 10.034 -17.595 1.00 57.06 C ATOM 1484 OG SER A 208 -7.847 11.392 -17.888 1.00 58.37 O ATOM 1485 N VAL A 209 -6.992 7.430 -16.107 1.00 62.23 N ATOM 1486 CA VAL A 209 -7.134 6.037 -15.719 1.00 66.20 C ATOM 1487 C VAL A 209 -7.127 5.922 -14.201 1.00 66.15 C ATOM 1488 O VAL A 209 -7.939 5.190 -13.622 1.00 63.48 O ATOM 1489 CB VAL A 209 -6.037 5.195 -16.393 1.00 68.42 C ATOM 1490 CG1 VAL A 209 -6.037 3.774 -15.854 1.00 63.67 C ATOM 1491 CG2 VAL A 209 -6.246 5.237 -17.963 1.00 65.72 C ATOM 1492 N GLY A 210 -6.269 6.699 -13.534 1.00 64.11 N ATOM 1493 CA GLY A 210 -6.208 6.693 -12.087 1.00 73.20 C ATOM 1494 C GLY A 210 -7.538 7.053 -11.483 1.00 70.08 C ATOM 1495 O GLY A 210 -8.140 6.286 -10.717 1.00 66.85 O ATOM 1496 N CYS A 211 -8.017 8.214 -11.911 1.00 63.63 N ATOM 1497 CA CYS A 211 -9.304 8.713 -11.472 1.00 66.10 C ATOM 1498 C CYS A 211 -10.411 7.696 -11.680 1.00 66.14 C ATOM 1499 O CYS A 211 -11.257 7.520 -10.799 1.00 62.62 O ATOM 1500 CB CYS A 211 -9.586 10.041 -12.189 1.00 64.97 C ATOM 1501 SG CYS A 211 -8.265 11.237 -11.850 1.00 65.88 S ATOM 1502 N ILE A 212 -10.395 6.983 -12.816 1.00 63.43 N ATOM 1503 CA ILE A 212 -11.463 6.031 -13.120 1.00 60.58 C ATOM 1504 C ILE A 212 -11.367 4.794 -12.232 1.00 65.19 C ATOM 1505 O ILE A 212 -12.374 4.312 -11.704 1.00 63.09 O ATOM 1506 CB ILE A 212 -11.429 5.635 -14.604 1.00 58.47 C ATOM 1507 CG1 ILE A 212 -11.974 6.768 -15.505 1.00 59.04 C ATOM 1508 CG2 ILE A 212 -12.142 4.314 -14.803 1.00 44.17 C ATOM 1509 CD1 ILE A 212 -11.491 6.654 -17.006 1.00 47.64 C ATOM 1510 N MET A 213 -10.167 4.223 -12.117 1.00 65.36 N ATOM 1511 CA MET A 213 -9.994 3.046 -11.283 1.00 64.19 C ATOM 1512 C MET A 213 -10.436 3.345 -9.864 1.00 71.82 C ATOM 1513 O MET A 213 -11.189 2.565 -9.266 1.00 68.57 O ATOM 1514 CB MET A 213 -8.542 2.576 -11.291 1.00 72.26 C ATOM 1515 CG MET A 213 -8.170 1.762 -10.070 1.00 67.82 C ATOM 1516 SD MET A 213 -6.847 0.580 -10.468 1.00 79.44 S ATOM 1517 CE MET A 213 -5.427 1.634 -10.621 1.00 81.38 C ATOM 1518 N ALA A 214 -10.018 4.503 -9.323 1.00 74.92 N ATOM 1519 CA ALA A 214 -10.405 4.831 -7.951 1.00 79.23 C ATOM 1520 C ALA A 214 -11.910 4.957 -7.866 1.00 74.61 C ATOM 1521 O ALA A 214 -12.532 4.481 -6.908 1.00 65.80 O ATOM 1522 CB ALA A 214 -9.726 6.124 -7.476 1.00 66.30 C ATOM 1523 N GLU A 215 -12.523 5.549 -8.898 1.00 64.79 N ATOM 1524 CA GLU A 215 -13.966 5.668 -8.851 1.00 66.23 C ATOM 1525 C GLU A 215 -14.658 4.324 -9.116 1.00 66.84 C ATOM 1526 O GLU A 215 -15.804 4.134 -8.699 1.00 68.08 O ATOM 1527 CB GLU A 215 -14.411 6.744 -9.821 1.00 59.24 C ATOM 1528 CG GLU A 215 -15.883 6.834 -9.957 1.00 62.41 C ATOM 1529 CD GLU A 215 -16.324 8.017 -10.779 1.00 65.06 C ATOM 1530 OE1 GLU A 215 -15.522 8.983 -10.981 1.00 67.84 O ATOM 1531 OE2 GLU A 215 -17.484 7.977 -11.244 1.00 64.21 O ATOM 1532 N LEU A 216 -13.994 3.364 -9.772 1.00 65.13 N ATOM 1533 CA LEU A 216 -14.657 2.072 -9.987 1.00 72.15 C ATOM 1534 C LEU A 216 -14.655 1.259 -8.703 1.00 73.82 C ATOM 1535 O LEU A 216 -15.641 0.586 -8.376 1.00 77.56 O ATOM 1536 CB LEU A 216 -13.981 1.275 -11.114 1.00 64.28 C ATOM 1537 CG LEU A 216 -14.064 1.683 -12.594 1.00 63.89 C ATOM 1538 CD1 LEU A 216 -13.435 0.582 -13.440 1.00 68.17 C ATOM 1539 CD2 LEU A 216 -15.477 1.966 -13.072 1.00 51.77 C ATOM 1540 N LEU A 217 -13.531 1.300 -7.986 1.00 73.87 N ATOM 1541 CA LEU A 217 -13.415 0.705 -6.664 1.00 72.99 C ATOM 1542 C LEU A 217 -14.471 1.242 -5.704 1.00 80.47 C ATOM 1543 O LEU A 217 -15.198 0.458 -5.086 1.00 92.53 O ATOM 1544 CB LEU A 217 -12.010 0.968 -6.147 1.00 71.53 C ATOM 1545 CG LEU A 217 -11.037 0.100 -6.940 1.00 77.75 C ATOM 1546 CD1 LEU A 217 -9.629 0.664 -6.938 1.00 75.27 C ATOM 1547 CD2 LEU A 217 -11.036 -1.274 -6.305 1.00 75.67 C ATOM 1548 N THR A 218 -14.597 2.573 -5.591 1.00 74.27 N ATOM 1549 CA THR A 218 -15.357 3.198 -4.509 1.00 75.37 C ATOM 1550 C THR A 218 -16.810 3.427 -4.856 1.00 72.37 C ATOM 1551 O THR A 218 -17.669 3.379 -3.972 1.00 83.01 O ATOM 1552 CB THR A 218 -14.756 4.559 -4.111 1.00 82.45 C ATOM 1553 OG1 THR A 218 -14.918 5.526 -5.186 1.00 77.80 O ATOM 1554 CG2 THR A 218 -13.278 4.419 -3.681 1.00 81.54 C ATOM 1555 N GLY A 219 -17.096 3.702 -6.110 1.00 74.72 N ATOM 1556 CA GLY A 219 -18.413 4.138 -6.505 1.00 77.62 C ATOM 1557 C GLY A 219 -18.622 5.631 -6.508 1.00 69.26 C ATOM 1558 O GLY A 219 -19.728 6.068 -6.841 1.00 73.30 O ATOM 1559 N ARG A 220 -17.603 6.433 -6.147 1.00 69.63 N ATOM 1560 CA ARG A 220 -17.746 7.892 -6.045 1.00 70.16 C ATOM 1561 C ARG A 220 -16.611 8.617 -6.772 1.00 61.89 C ATOM 1562 O ARG A 220 -15.437 8.248 -6.666 1.00 63.66 O ATOM 1563 CB ARG A 220 -17.790 8.345 -4.573 1.00 69.84 C ATOM 1564 N THR A 221 -16.962 9.650 -7.510 1.00 53.36 N ATOM 1565 CA THR A 221 -15.960 10.428 -8.231 1.00 62.90 C ATOM 1566 C THR A 221 -14.842 10.915 -7.306 1.00 68.40 C ATOM 1567 O THR A 221 -15.116 11.464 -6.241 1.00 67.56 O ATOM 1568 CB THR A 221 -16.654 11.609 -8.868 1.00 63.33 C ATOM 1569 OG1 THR A 221 -16.681 12.657 -7.914 1.00 73.31 O ATOM 1570 CG2 THR A 221 -18.082 11.244 -9.138 1.00 64.77 C ATOM 1571 N LEU A 222 -13.572 10.708 -7.710 1.00 65.97 N ATOM 1572 CA LEU A 222 -12.440 10.945 -6.802 1.00 65.78 C ATOM 1573 C LEU A 222 -12.212 12.435 -6.555 1.00 75.07 C ATOM 1574 O LEU A 222 -12.033 12.858 -5.408 1.00 78.78 O ATOM 1575 CB LEU A 222 -11.159 10.306 -7.338 1.00 59.47 C ATOM 1576 CG LEU A 222 -10.045 9.905 -6.335 1.00 73.93 C ATOM 1577 CD1 LEU A 222 -8.757 9.363 -6.967 1.00 81.00 C ATOM 1578 CD2 LEU A 222 -9.639 10.997 -5.421 1.00 78.49 C ATOM 1579 N PHE A 223 -12.195 13.235 -7.612 1.00 73.00 N ATOM 1580 CA PHE A 223 -11.921 14.669 -7.555 1.00 69.21 C ATOM 1581 C PHE A 223 -13.079 15.438 -8.167 1.00 69.24 C ATOM 1582 O PHE A 223 -12.912 16.079 -9.208 1.00 74.74 O ATOM 1583 CB PHE A 223 -10.645 15.003 -8.328 1.00 72.51 C ATOM 1584 CG PHE A 223 -9.419 14.286 -7.863 1.00 76.84 C ATOM 1585 CD1 PHE A 223 -8.992 14.413 -6.539 1.00 78.75 C ATOM 1586 CD2 PHE A 223 -8.657 13.538 -8.747 1.00 67.80 C ATOM 1587 CE1 PHE A 223 -7.834 13.779 -6.101 1.00 76.00 C ATOM 1588 CE2 PHE A 223 -7.503 12.901 -8.329 1.00 72.78 C ATOM 1589 CZ PHE A 223 -7.089 13.015 -6.992 1.00 81.02 C ATOM 1590 N PRO A 224 -14.256 15.387 -7.573 1.00 71.45 N ATOM 1591 CA PRO A 224 -15.377 16.165 -8.130 1.00 78.87 C ATOM 1592 C PRO A 224 -15.257 17.681 -7.976 1.00 87.98 C ATOM 1593 O PRO A 224 -16.143 18.313 -7.394 1.00 93.83 O ATOM 1594 CB PRO A 224 -16.590 15.637 -7.358 1.00 67.69 C ATOM 1595 CG PRO A 224 -16.018 15.141 -6.072 1.00 77.94 C ATOM 1596 CD PRO A 224 -14.650 14.588 -6.398 1.00 67.89 C ATOM 1597 N GLY A 225 -14.208 18.290 -8.522 1.00 85.99 N ATOM 1598 CA GLY A 225 -14.043 19.727 -8.367 1.00 93.43 C ATOM 1599 C GLY A 225 -15.208 20.505 -8.962 1.00102.14 C ATOM 1600 O GLY A 225 -15.740 20.165 -10.025 1.00 96.63 O ATOM 1601 N THR A 226 -15.583 21.588 -8.273 1.00107.47 N ATOM 1602 CA THR A 226 -16.746 22.391 -8.630 1.00103.74 C ATOM 1603 C THR A 226 -16.443 23.438 -9.696 1.00107.45 C ATOM 1604 O THR A 226 -17.332 23.802 -10.480 1.00105.34 O ATOM 1605 CB THR A 226 -17.300 23.058 -7.374 1.00103.86 C ATOM 1606 OG1 THR A 226 -16.288 23.884 -6.789 1.00108.85 O ATOM 1607 CG2 THR A 226 -17.705 21.996 -6.378 1.00106.50 C ATOM 1608 N ASP A 227 -15.211 23.929 -9.747 1.00105.43 N ATOM 1609 CA ASP A 227 -14.762 24.752 -10.858 1.00105.85 C ATOM 1610 C ASP A 227 -13.283 24.474 -11.050 1.00102.24 C ATOM 1611 O ASP A 227 -12.688 23.664 -10.333 1.00103.44 O ATOM 1612 CB ASP A 227 -15.037 26.252 -10.626 1.00106.86 C ATOM 1613 CG ASP A 227 -14.488 26.764 -9.307 1.00105.02 C ATOM 1614 OD1 ASP A 227 -13.263 26.679 -9.085 1.00106.33 O ATOM 1615 OD2 ASP A 227 -15.284 27.280 -8.498 1.00108.68 O ATOM 1616 N HIS A 228 -12.690 25.167 -12.022 1.00101.13 N ATOM 1617 CA HIS A 228 -11.273 24.982 -12.295 1.00102.91 C ATOM 1618 C HIS A 228 -10.444 25.153 -11.027 1.00105.55 C ATOM 1619 O HIS A 228 -9.514 24.379 -10.776 1.00104.09 O ATOM 1620 CB HIS A 228 -10.824 25.958 -13.387 1.00103.48 C ATOM 1621 N ILE A 229 -10.805 26.125 -10.187 1.00101.45 N ATOM 1622 CA ILE A 229 -10.013 26.404 -8.990 1.00108.95 C ATOM 1623 C ILE A 229 -10.194 25.298 -7.949 1.00101.00 C ATOM 1624 O ILE A 229 -9.216 24.770 -7.406 1.00100.30 O ATOM 1625 CB ILE A 229 -10.365 27.795 -8.422 1.00106.38 C ATOM 1626 N ASP A 230 -11.445 24.927 -7.657 1.00102.04 N ATOM 1627 CA ASP A 230 -11.694 23.874 -6.670 1.00105.04 C ATOM 1628 C ASP A 230 -11.022 22.562 -7.071 1.00105.03 C ATOM 1629 O ASP A 230 -10.467 21.854 -6.215 1.00 95.39 O ATOM 1630 CB ASP A 230 -13.201 23.669 -6.496 1.00105.40 C ATOM 1631 CG ASP A 230 -13.550 22.762 -5.315 1.00112.38 C ATOM 1632 OD1 ASP A 230 -12.662 22.065 -4.772 1.00110.59 O ATOM 1633 OD2 ASP A 230 -14.736 22.751 -4.925 1.00116.96 O ATOM 1634 N GLN A 231 -11.065 22.229 -8.374 1.00103.59 N ATOM 1635 CA GLN A 231 -10.493 20.980 -8.873 1.00 94.40 C ATOM 1636 C GLN A 231 -9.069 20.783 -8.370 1.00 99.38 C ATOM 1637 O GLN A 231 -8.757 19.761 -7.746 1.00 99.35 O ATOM 1638 CB GLN A 231 -10.537 20.961 -10.396 1.00 97.94 C ATOM 1639 CG GLN A 231 -9.995 19.688 -11.004 1.00 96.18 C ATOM 1640 CD GLN A 231 -10.966 18.524 -10.907 1.00 83.62 C ATOM 1641 OE1 GLN A 231 -12.175 18.678 -11.108 1.00 81.60 O ATOM 1642 NE2 GLN A 231 -10.442 17.360 -10.556 1.00 79.02 N ATOM 1643 N LEU A 232 -8.202 21.781 -8.590 1.00101.24 N ATOM 1644 CA LEU A 232 -6.829 21.699 -8.095 1.00101.59 C ATOM 1645 C LEU A 232 -6.791 21.495 -6.590 1.00 97.59 C ATOM 1646 O LEU A 232 -6.013 20.674 -6.088 1.00 97.02 O ATOM 1647 CB LEU A 232 -6.047 22.957 -8.468 1.00100.01 C ATOM 1648 N LYS A 233 -7.627 22.230 -5.855 1.00100.15 N ATOM 1649 CA LYS A 233 -7.636 22.104 -4.400 1.00100.15 C ATOM 1650 C LYS A 233 -7.905 20.665 -3.987 1.00 96.79 C ATOM 1651 O LYS A 233 -7.187 20.096 -3.153 1.00 95.39 O ATOM 1652 CB LYS A 233 -8.678 23.050 -3.797 1.00 99.73 C ATOM 1653 N LEU A 234 -8.929 20.050 -4.590 1.00 99.99 N ATOM 1654 CA LEU A 234 -9.179 18.633 -4.356 1.00 93.17 C ATOM 1655 C LEU A 234 -8.019 17.788 -4.858 1.00 87.07 C ATOM 1656 O LEU A 234 -7.631 16.813 -4.210 1.00 85.01 O ATOM 1657 CB LEU A 234 -10.478 18.215 -5.032 1.00 91.25 C ATOM 1658 CG LEU A 234 -11.733 18.993 -4.656 1.00 94.26 C ATOM 1659 N ILE A 235 -7.444 18.153 -6.009 1.00 93.41 N ATOM 1660 CA ILE A 235 -6.282 17.427 -6.527 1.00 93.60 C ATOM 1661 C ILE A 235 -5.170 17.416 -5.484 1.00 94.78 C ATOM 1662 O ILE A 235 -4.722 16.356 -5.027 1.00 89.84 O ATOM 1663 CB ILE A 235 -5.785 18.044 -7.852 1.00 92.57 C ATOM 1664 CG1 ILE A 235 -6.833 18.042 -8.973 1.00 90.87 C ATOM 1665 CG2 ILE A 235 -4.552 17.310 -8.335 1.00 91.50 C ATOM 1666 CD1 ILE A 235 -7.285 16.679 -9.488 1.00 80.60 C ATOM 1667 N LEU A 236 -4.713 18.614 -5.093 1.00 97.33 N ATOM 1668 CA LEU A 236 -3.586 18.721 -4.172 1.00101.38 C ATOM 1669 C LEU A 236 -3.917 18.140 -2.801 1.00103.36 C ATOM 1670 O LEU A 236 -3.018 17.647 -2.111 1.00112.22 O ATOM 1671 CB LEU A 236 -3.146 20.180 -4.047 1.00 93.31 C ATOM 1672 N ARG A 237 -5.196 18.152 -2.410 1.00 99.56 N ATOM 1673 CA ARG A 237 -5.583 17.621 -1.106 1.00104.88 C ATOM 1674 C ARG A 237 -5.159 16.166 -0.923 1.00105.12 C ATOM 1675 O ARG A 237 -4.840 15.754 0.197 1.00106.49 O ATOM 1676 CB ARG A 237 -7.095 17.758 -0.913 1.00102.59 C ATOM 1677 N LEU A 238 -5.145 15.374 -1.992 1.00101.88 N ATOM 1678 CA LEU A 238 -4.805 13.965 -1.860 1.00 99.15 C ATOM 1679 C LEU A 238 -3.362 13.661 -2.236 1.00103.06 C ATOM 1680 O LEU A 238 -2.667 12.954 -1.502 1.00106.69 O ATOM 1681 CB LEU A 238 -5.747 13.115 -2.710 1.00 98.76 C ATOM 1682 CG LEU A 238 -5.351 11.641 -2.802 1.00100.73 C ATOM 1683 N VAL A 239 -2.892 14.174 -3.375 1.00107.23 N ATOM 1684 CA VAL A 239 -1.590 13.760 -3.897 1.00111.03 C ATOM 1685 C VAL A 239 -0.434 14.569 -3.320 1.00118.63 C ATOM 1686 O VAL A 239 0.737 14.183 -3.490 1.00119.79 O ATOM 1687 CB VAL A 239 -1.608 13.840 -5.434 1.00102.55 C ATOM 1688 CG1 VAL A 239 -1.677 15.289 -5.881 1.00105.77 C ATOM 1689 CG2 VAL A 239 -0.403 13.127 -6.025 1.00 97.27 C ATOM 1690 N GLY A 240 -0.719 15.661 -2.623 1.00117.23 N ATOM 1691 CA GLY A 240 0.318 16.470 -2.020 1.00120.72 C ATOM 1692 C GLY A 240 0.690 17.658 -2.882 1.00127.31 C ATOM 1693 O GLY A 240 0.181 17.863 -3.990 1.00122.50 O ATOM 1694 N THR A 241 1.598 18.457 -2.339 1.00129.49 N ATOM 1695 CA THR A 241 2.071 19.627 -3.043 1.00129.90 C ATOM 1696 C THR A 241 3.111 19.232 -4.084 1.00134.64 C ATOM 1697 O THR A 241 3.718 18.158 -4.000 1.00133.11 O ATOM 1698 CB THR A 241 2.651 20.637 -2.058 1.00132.91 C ATOM 1699 OG1 THR A 241 3.464 19.956 -1.095 1.00133.87 O ATOM 1700 CG2 THR A 241 1.526 21.381 -1.357 1.00133.40 C ATOM 1701 N PRO A 242 3.311 20.074 -5.097 1.00134.47 N ATOM 1702 CA PRO A 242 4.324 19.773 -6.112 1.00135.21 C ATOM 1703 C PRO A 242 5.709 19.732 -5.489 1.00139.31 C ATOM 1704 O PRO A 242 6.105 20.643 -4.756 1.00137.19 O ATOM 1705 CB PRO A 242 4.179 20.930 -7.108 1.00132.51 C ATOM 1706 CG PRO A 242 2.844 21.507 -6.849 1.00126.74 C ATOM 1707 CD PRO A 242 2.604 21.332 -5.395 1.00127.75 C ATOM 1708 N GLY A 243 6.441 18.660 -5.786 1.00139.82 N ATOM 1709 CA GLY A 243 7.777 18.463 -5.254 1.00144.83 C ATOM 1710 C GLY A 243 8.816 19.442 -5.775 1.00148.68 C ATOM 1711 O GLY A 243 8.508 20.616 -6.018 1.00150.21 O ATOM 1712 N ALA A 244 10.049 18.963 -5.963 1.00146.44 N ATOM 1713 CA ALA A 244 11.181 19.824 -6.289 1.00148.47 C ATOM 1714 C ALA A 244 11.029 20.532 -7.629 1.00147.54 C ATOM 1715 O ALA A 244 10.844 21.753 -7.668 1.00147.96 O ATOM 1716 CB ALA A 244 12.477 19.013 -6.285 1.00147.21 C ATOM 1717 N GLU A 245 11.138 19.777 -8.725 1.00148.54 N ATOM 1718 CA GLU A 245 11.006 20.316 -10.075 1.00150.27 C ATOM 1719 C GLU A 245 9.715 21.114 -10.213 1.00147.83 C ATOM 1720 O GLU A 245 9.683 22.310 -9.908 1.00145.11 O ATOM 1721 CB GLU A 245 11.047 19.187 -11.110 1.00152.96 C ATOM 1722 CG GLU A 245 12.305 18.328 -11.084 1.00154.02 C ATOM 1723 CD GLU A 245 12.269 17.259 -10.010 1.00150.80 C ATOM 1724 OE1 GLU A 245 11.190 17.047 -9.417 1.00148.08 O ATOM 1725 OE2 GLU A 245 13.315 16.620 -9.774 1.00150.44 O ATOM 1726 N LEU A 246 8.664 20.467 -10.716 1.00150.01 N ATOM 1727 CA LEU A 246 7.294 20.937 -10.535 1.00147.45 C ATOM 1728 C LEU A 246 7.058 22.357 -11.032 1.00147.42 C ATOM 1729 O LEU A 246 6.648 22.563 -12.181 1.00147.41 O ATOM 1730 CB LEU A 246 6.926 20.845 -9.058 1.00144.35 C ATOM 1731 N LEU A 247 7.282 23.341 -10.151 1.00146.45 N ATOM 1732 CA LEU A 247 7.181 24.737 -10.561 1.00146.03 C ATOM 1733 C LEU A 247 8.188 25.055 -11.655 1.00142.44 C ATOM 1734 O LEU A 247 7.945 25.931 -12.494 1.00137.99 O ATOM 1735 CB LEU A 247 7.381 25.657 -9.355 1.00144.69 C ATOM 1736 N LYS A 248 9.318 24.345 -11.663 1.00144.80 N ATOM 1737 CA LYS A 248 10.274 24.390 -12.762 1.00145.54 C ATOM 1738 C LYS A 248 9.772 23.541 -13.925 1.00141.87 C ATOM 1739 O LYS A 248 10.492 22.657 -14.401 1.00142.05 O ATOM 1740 CB LYS A 248 11.650 23.902 -12.298 1.00145.03 C ATOM 1741 N LYS A 249 8.536 23.794 -14.374 1.00140.19 N ATOM 1742 CA LYS A 249 7.919 23.052 -15.470 1.00134.63 C ATOM 1743 C LYS A 249 6.636 23.731 -15.933 1.00131.05 C ATOM 1744 O LYS A 249 5.690 23.057 -16.359 1.00127.33 O ATOM 1745 CB LYS A 249 7.621 21.610 -15.053 1.00136.76 C ATOM 1746 N ILE A 250 6.594 25.058 -15.846 1.00130.84 N ATOM 1747 CA ILE A 250 5.463 25.830 -16.340 1.00125.18 C ATOM 1748 C ILE A 250 5.953 26.841 -17.369 1.00119.58 C ATOM 1749 O ILE A 250 6.186 28.006 -17.051 1.00121.87 O ATOM 1750 CB ILE A 250 4.713 26.526 -15.188 1.00127.99 C ATOM 1751 N SER A 261 2.194 29.177 -3.550 1.00143.68 N ATOM 1752 CA SER A 261 1.245 30.269 -3.353 1.00145.70 C ATOM 1753 C SER A 261 -0.052 29.790 -2.695 1.00146.53 C ATOM 1754 O SER A 261 -1.008 30.552 -2.549 1.00146.67 O ATOM 1755 CB SER A 261 0.938 30.959 -4.688 1.00146.33 C ATOM 1756 OG SER A 261 0.680 30.021 -5.721 1.00149.64 O ATOM 1757 N LEU A 262 -0.076 28.523 -2.295 1.00142.93 N ATOM 1758 CA LEU A 262 -1.199 27.948 -1.571 1.00142.66 C ATOM 1759 C LEU A 262 -0.649 27.093 -0.433 1.00145.91 C ATOM 1760 O LEU A 262 0.567 26.955 -0.270 1.00147.68 O ATOM 1761 CB LEU A 262 -2.103 27.136 -2.508 1.00139.60 C ATOM 1762 N ALA A 263 -1.553 26.515 0.359 1.00144.03 N ATOM 1763 CA ALA A 263 -1.142 25.756 1.535 1.00143.95 C ATOM 1764 C ALA A 263 -0.259 24.576 1.145 1.00142.80 C ATOM 1765 O ALA A 263 -0.500 23.908 0.139 1.00148.07 O ATOM 1766 CB ALA A 263 -2.371 25.262 2.297 1.00143.48 C ATOM 1767 N GLN A 264 0.768 24.314 1.959 1.00138.54 N ATOM 1768 CA GLN A 264 1.761 23.278 1.655 1.00139.70 C ATOM 1769 C GLN A 264 1.343 21.953 2.295 1.00139.96 C ATOM 1770 O GLN A 264 1.890 21.510 3.306 1.00141.37 O ATOM 1771 CB GLN A 264 3.145 23.711 2.120 1.00140.54 C ATOM 1772 N MET A 265 0.358 21.289 1.658 1.00140.12 N ATOM 1773 CA MET A 265 -0.141 19.989 2.081 1.00134.71 C ATOM 1774 C MET A 265 0.846 18.875 1.733 1.00135.70 C ATOM 1775 O MET A 265 1.575 18.965 0.743 1.00138.08 O ATOM 1776 CB MET A 265 -1.480 19.691 1.418 1.00131.69 C ATOM 1777 CG MET A 265 -2.669 20.396 2.044 1.00133.84 C ATOM 1778 SD MET A 265 -3.211 21.857 1.152 1.00136.69 S ATOM 1779 CE MET A 265 -4.034 21.115 -0.262 1.00124.00 C ATOM 1780 N PRO A 266 0.890 17.816 2.534 1.00137.09 N ATOM 1781 CA PRO A 266 1.772 16.683 2.246 1.00133.01 C ATOM 1782 C PRO A 266 1.056 15.605 1.438 1.00130.79 C ATOM 1783 O PRO A 266 -0.171 15.598 1.302 1.00126.50 O ATOM 1784 CB PRO A 266 2.118 16.173 3.649 1.00131.37 C ATOM 1785 CG PRO A 266 0.849 16.400 4.405 1.00131.53 C ATOM 1786 CD PRO A 266 0.248 17.682 3.854 1.00134.07 C ATOM 1787 N LYS A 267 1.856 14.677 0.915 1.00129.71 N ATOM 1788 CA LYS A 267 1.351 13.633 0.032 1.00128.73 C ATOM 1789 C LYS A 267 0.787 12.474 0.845 1.00129.67 C ATOM 1790 O LYS A 267 1.476 11.909 1.701 1.00127.09 O ATOM 1791 CB LYS A 267 2.458 13.134 -0.900 1.00128.25 C ATOM 1792 N MET A 268 -0.465 12.117 0.564 1.00127.21 N ATOM 1793 CA MET A 268 -1.119 11.041 1.291 1.00119.47 C ATOM 1794 C MET A 268 -0.475 9.705 0.963 1.00119.64 C ATOM 1795 O MET A 268 -0.152 9.417 -0.191 1.00125.28 O ATOM 1796 CB MET A 268 -2.603 10.987 0.936 1.00115.21 C ATOM 1797 CG MET A 268 -3.454 12.008 1.644 1.00115.53 C ATOM 1798 SD MET A 268 -3.931 11.378 3.257 1.00122.88 S ATOM 1799 CE MET A 268 -5.378 12.370 3.619 1.00125.87 C ATOM 1800 N ASN A 269 -0.278 8.889 1.989 1.00124.48 N ATOM 1801 CA ASN A 269 0.066 7.488 1.780 1.00125.05 C ATOM 1802 C ASN A 269 -1.192 6.756 1.329 1.00125.47 C ATOM 1803 O ASN A 269 -2.126 6.578 2.115 1.00123.79 O ATOM 1804 CB ASN A 269 0.638 6.879 3.054 1.00126.42 C ATOM 1805 CG ASN A 269 1.474 5.658 2.780 1.00131.57 C ATOM 1806 OD1 ASN A 269 1.160 4.557 3.229 1.00137.52 O ATOM 1807 ND2 ASN A 269 2.555 5.846 2.038 1.00131.99 N ATOM 1808 N PHE A 270 -1.209 6.337 0.059 1.00129.01 N ATOM 1809 CA PHE A 270 -2.432 5.884 -0.602 1.00125.17 C ATOM 1810 C PHE A 270 -3.103 4.734 0.137 1.00125.61 C ATOM 1811 O PHE A 270 -4.334 4.611 0.111 1.00123.92 O ATOM 1812 CB PHE A 270 -2.119 5.476 -2.047 1.00120.91 C ATOM 1813 CG PHE A 270 -1.265 6.470 -2.795 1.00120.92 C ATOM 1814 CD1 PHE A 270 -1.830 7.295 -3.766 1.00121.01 C ATOM 1815 CD2 PHE A 270 0.099 6.581 -2.532 1.00120.02 C ATOM 1816 CE1 PHE A 270 -1.045 8.218 -4.453 1.00119.74 C ATOM 1817 CE2 PHE A 270 0.888 7.496 -3.204 1.00119.26 C ATOM 1818 CZ PHE A 270 0.320 8.316 -4.173 1.00121.97 C ATOM 1819 N ALA A 271 -2.309 3.889 0.800 1.00129.37 N ATOM 1820 CA ALA A 271 -2.857 2.802 1.604 1.00126.96 C ATOM 1821 C ALA A 271 -3.844 3.321 2.640 1.00122.89 C ATOM 1822 O ALA A 271 -4.855 2.671 2.930 1.00119.73 O ATOM 1823 CB ALA A 271 -1.723 2.032 2.283 1.00129.61 C ATOM 1824 N ASN A 272 -3.583 4.508 3.185 1.00124.37 N ATOM 1825 CA ASN A 272 -4.451 5.077 4.211 1.00124.56 C ATOM 1826 C ASN A 272 -5.783 5.580 3.666 1.00119.68 C ATOM 1827 O ASN A 272 -6.718 5.782 4.443 1.00118.03 O ATOM 1828 CB ASN A 272 -3.727 6.218 4.924 1.00123.59 C ATOM 1829 CG ASN A 272 -2.396 5.795 5.486 1.00124.56 C ATOM 1830 OD1 ASN A 272 -1.422 6.543 5.424 1.00128.08 O ATOM 1831 ND2 ASN A 272 -2.338 4.583 6.024 1.00126.66 N ATOM 1832 N VAL A 273 -5.897 5.798 2.365 1.00119.93 N ATOM 1833 CA VAL A 273 -7.135 6.350 1.827 1.00115.95 C ATOM 1834 C VAL A 273 -8.081 5.259 1.372 1.00108.91 C ATOM 1835 O VAL A 273 -9.272 5.280 1.694 1.00107.10 O ATOM 1836 CB VAL A 273 -6.831 7.336 0.682 1.00115.03 C ATOM 1837 CG1 VAL A 273 -8.009 8.268 0.467 1.00110.99 C ATOM 1838 CG2 VAL A 273 -5.568 8.124 0.975 1.00114.45 C ATOM 1839 N PHE A 274 -7.573 4.290 0.631 1.00109.05 N ATOM 1840 CA PHE A 274 -8.421 3.283 -0.014 1.00110.29 C ATOM 1841 C PHE A 274 -8.490 2.033 0.860 1.00112.36 C ATOM 1842 O PHE A 274 -7.910 0.985 0.571 1.00114.08 O ATOM 1843 CB PHE A 274 -7.911 2.973 -1.422 1.00109.95 C ATOM 1844 CG PHE A 274 -7.935 4.168 -2.351 1.00108.24 C ATOM 1845 CD1 PHE A 274 -9.141 4.710 -2.777 1.00104.74 C ATOM 1846 CD2 PHE A 274 -6.754 4.730 -2.813 1.00108.55 C ATOM 1847 CE1 PHE A 274 -9.166 5.810 -3.638 1.00 98.92 C ATOM 1848 CE2 PHE A 274 -6.772 5.825 -3.675 1.00106.64 C ATOM 1849 CZ PHE A 274 -7.980 6.364 -4.088 1.00 96.69 C ATOM 1850 N ILE A 275 -9.231 2.171 1.957 1.00110.86 N ATOM 1851 CA ILE A 275 -9.274 1.126 2.971 1.00108.86 C ATOM 1852 C ILE A 275 -9.977 -0.104 2.415 1.00113.42 C ATOM 1853 O ILE A 275 -10.969 0.000 1.678 1.00107.76 O ATOM 1854 CB ILE A 275 -9.976 1.635 4.240 1.00106.98 C ATOM 1855 N GLY A 276 -9.465 -1.280 2.779 1.00111.32 N ATOM 1856 CA GLY A 276 -10.012 -2.530 2.307 1.00108.90 C ATOM 1857 C GLY A 276 -9.725 -2.829 0.861 1.00109.37 C ATOM 1858 O GLY A 276 -10.400 -3.679 0.274 1.00110.16 O ATOM 1859 N ALA A 277 -8.763 -2.146 0.263 1.00109.56 N ATOM 1860 CA ALA A 277 -8.363 -2.424 -1.105 1.00105.90 C ATOM 1861 C ALA A 277 -7.246 -3.444 -1.125 1.00109.14 C ATOM 1862 O ALA A 277 -6.448 -3.527 -0.187 1.00111.62 O ATOM 1863 CB ALA A 277 -7.885 -1.147 -1.794 1.00106.73 C ATOM 1864 N ASN A 278 -7.205 -4.232 -2.188 1.00109.41 N ATOM 1865 CA ASN A 278 -6.000 -4.982 -2.481 1.00112.11 C ATOM 1866 C ASN A 278 -4.821 -4.025 -2.382 1.00112.75 C ATOM 1867 O ASN A 278 -4.822 -2.991 -3.058 1.00114.22 O ATOM 1868 CB ASN A 278 -6.061 -5.601 -3.883 1.00110.07 C ATOM 1869 CG ASN A 278 -4.750 -6.282 -4.297 1.00108.53 C ATOM 1870 OD1 ASN A 278 -3.769 -6.293 -3.560 1.00115.34 O ATOM 1871 ND2 ASN A 278 -4.756 -6.886 -5.459 1.00100.06 N ATOM 1872 N PRO A 279 -3.840 -4.292 -1.518 1.00117.67 N ATOM 1873 CA PRO A 279 -2.644 -3.436 -1.508 1.00118.51 C ATOM 1874 C PRO A 279 -1.912 -3.402 -2.846 1.00118.86 C ATOM 1875 O PRO A 279 -1.240 -2.404 -3.153 1.00118.48 O ATOM 1876 CB PRO A 279 -1.786 -4.037 -0.390 1.00126.55 C ATOM 1877 CG PRO A 279 -2.777 -4.726 0.510 1.00127.90 C ATOM 1878 CD PRO A 279 -3.825 -5.275 -0.420 1.00122.88 C ATOM 1879 N LEU A 280 -2.035 -4.454 -3.663 1.00115.00 N ATOM 1880 CA LEU A 280 -1.455 -4.423 -5.001 1.00111.46 C ATOM 1881 C LEU A 280 -2.123 -3.353 -5.867 1.00110.61 C ATOM 1882 O LEU A 280 -1.463 -2.703 -6.689 1.00104.25 O ATOM 1883 CB LEU A 280 -1.570 -5.805 -5.641 1.00105.31 C ATOM 1884 CG LEU A 280 -0.449 -6.132 -6.627 1.00105.47 C ATOM 1885 N ALA A 281 -3.427 -3.135 -5.669 1.00110.00 N ATOM 1886 CA ALA A 281 -4.157 -2.142 -6.449 1.00105.27 C ATOM 1887 C ALA A 281 -3.773 -0.721 -6.056 1.00106.57 C ATOM 1888 O ALA A 281 -3.660 0.160 -6.920 1.00106.92 O ATOM 1889 CB ALA A 281 -5.660 -2.347 -6.271 1.00106.10 C ATOM 1890 N VAL A 282 -3.586 -0.467 -4.759 1.00102.03 N ATOM 1891 CA VAL A 282 -3.267 0.895 -4.353 1.00101.47 C ATOM 1892 C VAL A 282 -1.855 1.271 -4.790 1.00 97.81 C ATOM 1893 O VAL A 282 -1.587 2.435 -5.095 1.00 98.53 O ATOM 1894 CB VAL A 282 -3.484 1.074 -2.833 1.00110.80 C ATOM 1895 CG1 VAL A 282 -4.972 1.050 -2.503 1.00108.09 C ATOM 1896 CG2 VAL A 282 -2.759 0.012 -2.037 1.00108.98 C ATOM 1897 N ASP A 283 -0.937 0.308 -4.854 1.00 98.85 N ATOM 1898 CA ASP A 283 0.405 0.619 -5.338 1.00103.18 C ATOM 1899 C ASP A 283 0.365 1.121 -6.778 1.00108.14 C ATOM 1900 O ASP A 283 1.115 2.033 -7.148 1.00105.09 O ATOM 1901 CB ASP A 283 1.307 -0.610 -5.220 1.00109.85 C ATOM 1902 CG ASP A 283 2.743 -0.334 -5.656 1.00115.54 C ATOM 1903 OD1 ASP A 283 3.160 0.843 -5.627 1.00120.94 O ATOM 1904 OD2 ASP A 283 3.453 -1.292 -6.040 1.00116.66 O ATOM 1905 N LEU A 284 -0.505 0.535 -7.608 1.00106.10 N ATOM 1906 CA LEU A 284 -0.684 1.044 -8.965 1.00100.14 C ATOM 1907 C LEU A 284 -1.297 2.440 -8.948 1.00 96.27 C ATOM 1908 O LEU A 284 -0.785 3.360 -9.600 1.00 93.48 O ATOM 1909 CB LEU A 284 -1.549 0.086 -9.794 1.00 97.54 C ATOM 1910 CG LEU A 284 -1.818 0.491 -11.252 1.00 94.88 C ATOM 1911 CD1 LEU A 284 -0.521 0.615 -12.035 1.00 94.43 C ATOM 1912 CD2 LEU A 284 -2.751 -0.491 -11.935 1.00 90.02 C ATOM 1913 N LEU A 285 -2.401 2.616 -8.211 1.00 93.01 N ATOM 1914 CA LEU A 285 -2.988 3.943 -8.076 1.00 91.51 C ATOM 1915 C LEU A 285 -1.934 4.973 -7.702 1.00 97.23 C ATOM 1916 O LEU A 285 -1.933 6.095 -8.223 1.00 91.69 O ATOM 1917 CB LEU A 285 -4.093 3.918 -7.028 1.00 92.41 C ATOM 1918 CG LEU A 285 -5.516 3.692 -7.492 1.00 90.66 C ATOM 1919 CD1 LEU A 285 -6.406 3.570 -6.267 1.00 91.04 C ATOM 1920 CD2 LEU A 285 -5.954 4.876 -8.359 1.00 80.05 C ATOM 1921 N GLU A 286 -1.020 4.594 -6.805 1.00104.81 N ATOM 1922 CA GLU A 286 0.063 5.483 -6.403 1.00104.74 C ATOM 1923 C GLU A 286 0.949 5.836 -7.586 1.00102.56 C ATOM 1924 O GLU A 286 1.389 6.986 -7.720 1.00104.82 O ATOM 1925 CB GLU A 286 0.891 4.822 -5.301 1.00110.84 C ATOM 1926 N LYS A 287 1.216 4.859 -8.462 1.00 96.20 N ATOM 1927 CA LYS A 287 2.113 5.075 -9.591 1.00 95.16 C ATOM 1928 C LYS A 287 1.462 5.915 -10.677 1.00 94.31 C ATOM 1929 O LYS A 287 2.151 6.655 -11.385 1.00 91.63 O ATOM 1930 CB LYS A 287 2.571 3.729 -10.169 1.00 97.96 C ATOM 1931 N MET A 288 0.145 5.829 -10.807 1.00 92.55 N ATOM 1932 CA MET A 288 -0.553 6.541 -11.860 1.00 88.83 C ATOM 1933 C MET A 288 -0.909 7.959 -11.470 1.00 92.02 C ATOM 1934 O MET A 288 -0.945 8.844 -12.334 1.00 88.08 O ATOM 1935 CB MET A 288 -1.832 5.798 -12.238 1.00 88.43 C ATOM 1936 CG MET A 288 -1.561 4.438 -12.800 1.00 84.20 C ATOM 1937 SD MET A 288 -2.966 3.594 -13.501 1.00 83.60 S ATOM 1938 CE MET A 288 -4.280 4.182 -12.500 1.00 75.17 C ATOM 1939 N LEU A 289 -1.189 8.207 -10.201 1.00 92.46 N ATOM 1940 CA LEU A 289 -1.632 9.548 -9.832 1.00 87.41 C ATOM 1941 C LEU A 289 -0.466 10.405 -9.361 1.00 88.40 C ATOM 1942 O LEU A 289 -0.554 11.070 -8.343 1.00 93.10 O ATOM 1943 CB LEU A 289 -2.723 9.457 -8.781 1.00 87.61 C ATOM 1944 CG LEU A 289 -4.010 8.806 -9.286 1.00 84.84 C ATOM 1945 CD1 LEU A 289 -4.974 8.441 -8.111 1.00 72.92 C ATOM 1946 CD2 LEU A 289 -4.678 9.736 -10.322 1.00 75.26 C ATOM 1947 N VAL A 290 0.644 10.399 -10.094 1.00 89.96 N ATOM 1948 CA VAL A 290 1.809 11.206 -9.747 1.00 88.21 C ATOM 1949 C VAL A 290 1.699 12.539 -10.472 1.00 93.99 C ATOM 1950 O VAL A 290 1.423 12.577 -11.677 1.00 97.16 O ATOM 1951 CB VAL A 290 3.115 10.484 -10.117 1.00 91.62 C ATOM 1952 N LEU A 291 1.931 13.633 -9.746 1.00 92.05 N ATOM 1953 CA LEU A 291 1.733 14.961 -10.321 1.00 96.13 C ATOM 1954 C LEU A 291 2.683 15.225 -11.495 1.00 98.37 C ATOM 1955 O LEU A 291 2.251 15.703 -12.556 1.00105.61 O ATOM 1956 CB LEU A 291 1.891 16.017 -9.223 1.00101.75 C ATOM 1957 CG LEU A 291 1.253 17.393 -9.442 1.00 96.91 C ATOM 1958 CD1 LEU A 291 1.901 18.151 -10.613 1.00101.69 C ATOM 1959 CD2 LEU A 291 -0.249 17.267 -9.646 1.00 92.32 C ATOM 1960 N ASP A 292 3.972 14.919 -11.341 1.00 98.13 N ATOM 1961 CA ASP A 292 4.944 15.208 -12.398 1.00102.28 C ATOM 1962 C ASP A 292 4.791 14.178 -13.514 1.00 97.96 C ATOM 1963 O ASP A 292 5.072 12.986 -13.323 1.00 98.39 O ATOM 1964 CB ASP A 292 6.366 15.221 -11.847 1.00100.92 C ATOM 1965 N SER A 293 4.336 14.650 -14.676 1.00100.31 N ATOM 1966 CA SER A 293 4.109 13.812 -15.846 1.00 96.44 C ATOM 1967 C SER A 293 5.273 12.871 -16.114 1.00 99.06 C ATOM 1968 O SER A 293 5.069 11.697 -16.452 1.00 96.59 O ATOM 1969 CB SER A 293 3.875 14.671 -17.074 1.00 92.72 C ATOM 1970 OG SER A 293 4.353 13.990 -18.221 1.00 97.34 O ATOM 1971 N ASP A 294 6.498 13.386 -15.964 1.00100.74 N ATOM 1972 CA ASP A 294 7.691 12.569 -16.143 1.00 99.86 C ATOM 1973 C ASP A 294 7.696 11.350 -15.240 1.00 97.14 C ATOM 1974 O ASP A 294 8.337 10.345 -15.578 1.00104.61 O ATOM 1975 CB ASP A 294 8.947 13.397 -15.871 1.00 98.18 C ATOM 1976 N LYS A 295 6.981 11.403 -14.116 1.00 93.79 N ATOM 1977 CA LYS A 295 7.028 10.327 -13.139 1.00 99.79 C ATOM 1978 C LYS A 295 5.892 9.318 -13.267 1.00102.59 C ATOM 1979 O LYS A 295 6.009 8.218 -12.714 1.00100.02 O ATOM 1980 CB LYS A 295 7.016 10.910 -11.717 1.00 97.52 C ATOM 1981 N ARG A 296 4.811 9.649 -13.975 1.00101.26 N ATOM 1982 CA ARG A 296 3.668 8.746 -14.037 1.00 93.28 C ATOM 1983 C ARG A 296 4.022 7.476 -14.786 1.00 87.95 C ATOM 1984 O ARG A 296 4.860 7.469 -15.689 1.00 92.73 O ATOM 1985 CB ARG A 296 2.463 9.405 -14.693 1.00 91.14 C ATOM 1986 CG ARG A 296 1.982 10.592 -13.912 1.00 92.45 C ATOM 1987 CD ARG A 296 0.518 10.872 -14.106 1.00 81.89 C ATOM 1988 NE ARG A 296 0.331 11.720 -15.255 1.00 85.33 N ATOM 1989 CZ ARG A 296 0.203 13.040 -15.230 1.00 91.92 C ATOM 1990 NH1 ARG A 296 0.234 13.714 -14.088 1.00 87.25 N ATOM 1991 NH2 ARG A 296 0.039 13.691 -16.374 1.00 88.23 N ATOM 1992 N ILE A 297 3.376 6.384 -14.381 1.00 88.71 N ATOM 1993 CA ILE A 297 3.562 5.114 -15.057 1.00 89.58 C ATOM 1994 C ILE A 297 2.913 5.188 -16.432 1.00 90.83 C ATOM 1995 O ILE A 297 1.950 5.938 -16.652 1.00 91.05 O ATOM 1996 CB ILE A 297 2.960 3.986 -14.202 1.00 89.87 C ATOM 1997 CG1 ILE A 297 3.364 2.614 -14.735 1.00 87.78 C ATOM 1998 CG2 ILE A 297 1.471 4.148 -14.073 1.00 86.02 C ATOM 1999 CD1 ILE A 297 4.786 2.297 -14.418 1.00 92.82 C ATOM 2000 N THR A 298 3.455 4.425 -17.374 1.00 95.02 N ATOM 2001 CA THR A 298 2.909 4.368 -18.720 1.00 90.80 C ATOM 2002 C THR A 298 2.002 3.155 -18.868 1.00 96.63 C ATOM 2003 O THR A 298 2.067 2.195 -18.093 1.00 95.08 O ATOM 2004 CB THR A 298 4.016 4.322 -19.777 1.00 95.13 C ATOM 2005 OG1 THR A 298 4.555 2.994 -19.882 1.00 92.17 O ATOM 2006 CG2 THR A 298 5.119 5.316 -19.433 1.00 91.13 C ATOM 2007 N ALA A 299 1.137 3.217 -19.882 1.00 91.38 N ATOM 2008 CA ALA A 299 0.230 2.108 -20.133 1.00 86.50 C ATOM 2009 C ALA A 299 1.011 0.822 -20.322 1.00 89.09 C ATOM 2010 O ALA A 299 0.720 -0.199 -19.696 1.00 90.56 O ATOM 2011 CB ALA A 299 -0.624 2.396 -21.370 1.00 82.88 C ATOM 2012 N ALA A 300 1.985 0.850 -21.228 1.00 93.28 N ATOM 2013 CA ALA A 300 2.778 -0.343 -21.471 1.00 89.59 C ATOM 2014 C ALA A 300 3.459 -0.772 -20.197 1.00 96.78 C ATOM 2015 O ALA A 300 3.489 -1.964 -19.867 1.00 99.08 O ATOM 2016 CB ALA A 300 3.809 -0.085 -22.563 1.00 99.64 C ATOM 2017 N GLN A 301 3.968 0.200 -19.438 1.00 97.40 N ATOM 2018 CA GLN A 301 4.550 -0.117 -18.138 1.00100.04 C ATOM 2019 C GLN A 301 3.495 -0.665 -17.179 1.00 96.40 C ATOM 2020 O GLN A 301 3.699 -1.713 -16.559 1.00 96.59 O ATOM 2021 CB GLN A 301 5.236 1.114 -17.541 1.00 96.41 C ATOM 2022 CG GLN A 301 6.532 1.550 -18.223 1.00100.62 C ATOM 2023 CD GLN A 301 6.989 2.928 -17.754 1.00101.39 C ATOM 2024 OE1 GLN A 301 6.347 3.548 -16.901 1.00102.74 O ATOM 2025 NE2 GLN A 301 8.087 3.419 -18.320 1.00101.69 N ATOM 2026 N ALA A 302 2.353 0.018 -17.060 1.00 93.34 N ATOM 2027 CA ALA A 302 1.359 -0.366 -16.064 1.00 91.62 C ATOM 2028 C ALA A 302 0.820 -1.769 -16.311 1.00 94.79 C ATOM 2029 O ALA A 302 0.336 -2.422 -15.374 1.00 96.76 O ATOM 2030 CB ALA A 302 0.216 0.643 -16.042 1.00 89.04 C ATOM 2031 N LEU A 303 0.907 -2.254 -17.552 1.00 86.60 N ATOM 2032 CA LEU A 303 0.349 -3.563 -17.873 1.00 91.04 C ATOM 2033 C LEU A 303 1.104 -4.679 -17.163 1.00 98.72 C ATOM 2034 O LEU A 303 0.492 -5.620 -16.641 1.00101.27 O ATOM 2035 CB LEU A 303 0.379 -3.787 -19.385 1.00 95.27 C ATOM 2036 CG LEU A 303 -0.558 -2.928 -20.243 1.00 89.24 C ATOM 2037 CD1 LEU A 303 -0.054 -2.875 -21.675 1.00 91.61 C ATOM 2038 CD2 LEU A 303 -1.966 -3.482 -20.209 1.00 83.23 C ATOM 2039 N ALA A 304 2.437 -4.583 -17.124 1.00 98.20 N ATOM 2040 CA ALA A 304 3.272 -5.639 -16.563 1.00102.70 C ATOM 2041 C ALA A 304 3.182 -5.744 -15.041 1.00102.39 C ATOM 2042 O ALA A 304 3.655 -6.739 -14.484 1.00105.77 O ATOM 2043 CB ALA A 304 4.726 -5.420 -16.991 1.00 98.69 C ATOM 2044 N HIS A 305 2.572 -4.769 -14.369 1.00 97.04 N ATOM 2045 CA HIS A 305 2.551 -4.765 -12.920 1.00100.55 C ATOM 2046 C HIS A 305 1.665 -5.901 -12.417 1.00104.70 C ATOM 2047 O HIS A 305 0.813 -6.430 -13.142 1.00102.70 O ATOM 2048 CB HIS A 305 2.112 -3.389 -12.416 1.00104.95 C ATOM 2049 CG HIS A 305 1.544 -3.378 -11.031 1.00104.46 C ATOM 2050 ND1 HIS A 305 0.271 -3.786 -10.738 1.00104.77 N ATOM 2051 CD2 HIS A 305 2.106 -3.033 -9.848 1.00109.05 C ATOM 2052 CE1 HIS A 305 0.064 -3.662 -9.436 1.00107.56 C ATOM 2053 NE2 HIS A 305 1.166 -3.214 -8.870 1.00110.66 N ATOM 2054 N ALA A 306 1.899 -6.288 -11.152 1.00105.19 N ATOM 2055 CA ALA A 306 1.416 -7.559 -10.606 1.00105.38 C ATOM 2056 C ALA A 306 -0.088 -7.591 -10.352 1.00106.58 C ATOM 2057 O ALA A 306 -0.652 -8.684 -10.268 1.00111.27 O ATOM 2058 CB ALA A 306 2.163 -7.878 -9.309 1.00106.92 C ATOM 2059 N TYR A 307 -0.746 -6.435 -10.201 1.00101.85 N ATOM 2060 CA TYR A 307 -2.205 -6.428 -10.076 1.00101.03 C ATOM 2061 C TYR A 307 -2.858 -7.079 -11.279 1.00100.58 C ATOM 2062 O TYR A 307 -3.922 -7.705 -11.161 1.00 98.76 O ATOM 2063 CB TYR A 307 -2.701 -5.005 -9.933 1.00 98.71 C ATOM 2064 CG TYR A 307 -4.137 -4.819 -9.564 1.00 96.69 C ATOM 2065 CD1 TYR A 307 -4.708 -5.534 -8.544 1.00 96.07 C ATOM 2066 CD2 TYR A 307 -4.914 -3.858 -10.207 1.00 94.51 C ATOM 2067 CE1 TYR A 307 -6.015 -5.335 -8.179 1.00 98.30 C ATOM 2068 CE2 TYR A 307 -6.220 -3.650 -9.860 1.00 90.65 C ATOM 2069 CZ TYR A 307 -6.766 -4.394 -8.842 1.00 97.34 C ATOM 2070 OH TYR A 307 -8.071 -4.193 -8.481 1.00 97.16 O ATOM 2071 N PHE A 308 -2.245 -6.927 -12.446 1.00 97.08 N ATOM 2072 CA PHE A 308 -2.733 -7.560 -13.650 1.00 94.57 C ATOM 2073 C PHE A 308 -2.017 -8.856 -13.949 1.00 97.72 C ATOM 2074 O PHE A 308 -2.186 -9.391 -15.046 1.00 95.67 O ATOM 2075 CB PHE A 308 -2.601 -6.610 -14.833 1.00 90.31 C ATOM 2076 CG PHE A 308 -3.199 -5.272 -14.584 1.00 89.11 C ATOM 2077 CD1 PHE A 308 -2.410 -4.138 -14.597 1.00 86.03 C ATOM 2078 CD2 PHE A 308 -4.552 -5.154 -14.302 1.00 85.66 C ATOM 2079 CE1 PHE A 308 -2.962 -2.923 -14.361 1.00 87.63 C ATOM 2080 CE2 PHE A 308 -5.109 -3.930 -14.056 1.00 80.34 C ATOM 2081 CZ PHE A 308 -4.318 -2.815 -14.086 1.00 85.23 C ATOM 2082 N ALA A 309 -1.241 -9.391 -13.000 1.00 99.57 N ATOM 2083 CA ALA A 309 -0.502 -10.620 -13.286 1.00102.45 C ATOM 2084 C ALA A 309 -1.429 -11.749 -13.723 1.00 98.02 C ATOM 2085 O ALA A 309 -1.030 -12.581 -14.542 1.00101.14 O ATOM 2086 CB ALA A 309 0.326 -11.046 -12.077 1.00101.29 C ATOM 2087 N GLN A 310 -2.674 -11.768 -13.225 1.00 93.95 N ATOM 2088 CA GLN A 310 -3.639 -12.785 -13.638 1.00 91.37 C ATOM 2089 C GLN A 310 -3.992 -12.659 -15.118 1.00 93.81 C ATOM 2090 O GLN A 310 -4.192 -13.666 -15.804 1.00 98.83 O ATOM 2091 CB GLN A 310 -4.898 -12.684 -12.777 1.00 91.93 C ATOM 2092 CG GLN A 310 -6.036 -13.595 -13.213 1.00 92.27 C ATOM 2093 CD GLN A 310 -7.358 -13.247 -12.541 1.00 93.79 C ATOM 2094 OE1 GLN A 310 -7.406 -12.436 -11.606 1.00 96.18 O ATOM 2095 NE2 GLN A 310 -8.440 -13.865 -13.013 1.00 89.58 N ATOM 2096 N TYR A 311 -4.073 -11.436 -15.633 1.00 93.18 N ATOM 2097 CA TYR A 311 -4.386 -11.234 -17.043 1.00 93.93 C ATOM 2098 C TYR A 311 -3.170 -10.809 -17.861 1.00 91.90 C ATOM 2099 O TYR A 311 -3.176 -10.972 -19.088 1.00 91.31 O ATOM 2100 CB TYR A 311 -5.492 -10.188 -17.197 1.00 88.17 C ATOM 2101 CG TYR A 311 -6.756 -10.418 -16.378 1.00 84.18 C ATOM 2102 CD1 TYR A 311 -7.794 -11.208 -16.853 1.00 78.36 C ATOM 2103 CD2 TYR A 311 -6.911 -9.821 -15.138 1.00 81.45 C ATOM 2104 CE1 TYR A 311 -8.966 -11.400 -16.087 1.00 77.92 C ATOM 2105 CE2 TYR A 311 -8.065 -10.008 -14.374 1.00 83.78 C ATOM 2106 CZ TYR A 311 -9.087 -10.792 -14.843 1.00 77.80 C ATOM 2107 OH TYR A 311 -10.216 -10.939 -14.049 1.00 72.19 O ATOM 2108 N HIS A 312 -2.140 -10.276 -17.202 1.00 98.19 N ATOM 2109 CA HIS A 312 -0.905 -9.854 -17.851 1.00 96.54 C ATOM 2110 C HIS A 312 -0.330 -10.969 -18.700 1.00 98.70 C ATOM 2111 O HIS A 312 0.049 -12.025 -18.182 1.00103.19 O ATOM 2112 CB HIS A 312 0.106 -9.397 -16.789 1.00 99.46 C ATOM 2113 CG HIS A 312 1.440 -9.010 -17.340 1.00100.13 C ATOM 2114 ND1 HIS A 312 1.585 -8.314 -18.519 1.00104.09 N ATOM 2115 CD2 HIS A 312 2.693 -9.207 -16.862 1.00104.43 C ATOM 2116 CE1 HIS A 312 2.872 -8.117 -18.752 1.00106.35 C ATOM 2117 NE2 HIS A 312 3.566 -8.646 -17.760 1.00102.08 N ATOM 2118 N ASP A 313 -0.266 -10.715 -20.002 1.00101.56 N ATOM 2119 CA ASP A 313 0.255 -11.678 -20.973 1.00102.00 C ATOM 2120 C ASP A 313 0.978 -10.873 -22.037 1.00103.48 C ATOM 2121 O ASP A 313 0.369 -10.422 -23.016 1.00103.52 O ATOM 2122 CB ASP A 313 -0.867 -12.518 -21.580 1.00101.96 C ATOM 2123 CG ASP A 313 -0.411 -13.405 -22.752 1.00110.46 C ATOM 2124 OD1 ASP A 313 0.750 -13.320 -23.225 1.00110.01 O ATOM 2125 OD2 ASP A 313 -1.262 -14.184 -23.228 1.00106.22 O ATOM 2126 N PRO A 314 2.290 -10.657 -21.871 1.00104.71 N ATOM 2127 CA PRO A 314 3.072 -9.891 -22.857 1.00104.40 C ATOM 2128 C PRO A 314 2.901 -10.360 -24.296 1.00107.71 C ATOM 2129 O PRO A 314 3.075 -9.579 -25.241 1.00102.42 O ATOM 2130 CB PRO A 314 4.512 -10.087 -22.365 1.00106.50 C ATOM 2131 CG PRO A 314 4.354 -10.193 -20.867 1.00108.03 C ATOM 2132 CD PRO A 314 3.049 -10.914 -20.634 1.00106.97 C ATOM 2133 N ASP A 315 2.532 -11.621 -24.487 1.00106.04 N ATOM 2134 CA ASP A 315 2.359 -12.132 -25.838 1.00107.77 C ATOM 2135 C ASP A 315 0.990 -11.815 -26.435 1.00106.62 C ATOM 2136 O ASP A 315 0.719 -12.237 -27.565 1.00103.44 O ATOM 2137 CB ASP A 315 2.602 -13.643 -25.863 1.00103.84 C ATOM 2138 N ASP A 316 0.132 -11.076 -25.721 1.00103.21 N ATOM 2139 CA ASP A 316 -1.204 -10.715 -26.212 1.00 96.93 C ATOM 2140 C ASP A 316 -1.524 -9.262 -25.886 1.00 97.90 C ATOM 2141 O ASP A 316 -2.632 -8.933 -25.451 1.00100.08 O ATOM 2142 CB ASP A 316 -2.283 -11.630 -25.630 1.00 99.38 C ATOM 2143 CG ASP A 316 -3.623 -11.473 -26.332 1.00 91.01 C ATOM 2144 OD1 ASP A 316 -3.623 -11.080 -27.514 1.00 98.50 O ATOM 2145 OD2 ASP A 316 -4.675 -11.745 -25.712 1.00 94.65 O ATOM 2146 N GLU A 317 -0.562 -8.364 -26.074 1.00 94.76 N ATOM 2147 CA GLU A 317 -0.747 -6.946 -25.755 1.00 94.11 C ATOM 2148 C GLU A 317 -0.182 -6.107 -26.892 1.00 89.01 C ATOM 2149 O GLU A 317 0.871 -5.470 -26.766 1.00 88.59 O ATOM 2150 CB GLU A 317 -0.119 -6.617 -24.399 1.00 92.85 C ATOM 2151 CG GLU A 317 -0.934 -7.279 -23.272 1.00 93.96 C ATOM 2152 CD GLU A 317 -0.250 -7.339 -21.926 1.00 96.77 C ATOM 2153 OE1 GLU A 317 -0.815 -8.006 -21.028 1.00 95.72 O ATOM 2154 OE2 GLU A 317 0.831 -6.733 -21.762 1.00100.72 O ATOM 2155 N PRO A 318 -0.877 -6.078 -28.025 1.00 88.07 N ATOM 2156 CA PRO A 318 -0.253 -5.605 -29.264 1.00 88.57 C ATOM 2157 C PRO A 318 -0.244 -4.095 -29.453 1.00 84.63 C ATOM 2158 O PRO A 318 -1.013 -3.334 -28.856 1.00 81.18 O ATOM 2159 CB PRO A 318 -1.106 -6.266 -30.358 1.00 90.78 C ATOM 2160 CG PRO A 318 -2.442 -6.449 -29.723 1.00 89.05 C ATOM 2161 CD PRO A 318 -2.147 -6.790 -28.291 1.00 88.90 C ATOM 2162 N VAL A 319 0.629 -3.704 -30.377 1.00 90.78 N ATOM 2163 CA VAL A 319 0.889 -2.332 -30.776 1.00 88.13 C ATOM 2164 C VAL A 319 0.218 -2.086 -32.128 1.00 83.29 C ATOM 2165 O VAL A 319 0.035 -3.004 -32.931 1.00 81.90 O ATOM 2166 CB VAL A 319 2.417 -2.101 -30.844 1.00 82.82 C ATOM 2167 CG1 VAL A 319 3.012 -2.724 -32.102 1.00 93.49 C ATOM 2168 CG2 VAL A 319 2.743 -0.697 -30.842 1.00 83.99 C ATOM 2169 N ALA A 320 -0.159 -0.831 -32.384 1.00 88.99 N ATOM 2170 CA ALA A 320 -0.794 -0.462 -33.653 1.00 84.30 C ATOM 2171 C ALA A 320 0.243 -0.242 -34.750 1.00 91.33 C ATOM 2172 O ALA A 320 1.383 0.147 -34.478 1.00 91.69 O ATOM 2173 CB ALA A 320 -1.627 0.820 -33.513 1.00 71.21 C ATOM 2174 N ASP A 321 -0.180 -0.450 -36.006 1.00 81.99 N ATOM 2175 CA ASP A 321 0.633 -0.050 -37.143 1.00 90.23 C ATOM 2176 C ASP A 321 0.811 1.468 -37.157 1.00 90.42 C ATOM 2177 O ASP A 321 -0.001 2.208 -36.603 1.00 87.05 O ATOM 2178 CB ASP A 321 -0.008 -0.512 -38.464 1.00 86.66 C ATOM 2179 CG ASP A 321 -0.155 -2.017 -38.537 1.00 94.14 C ATOM 2180 OD1 ASP A 321 0.528 -2.714 -37.753 1.00 99.65 O ATOM 2181 OD2 ASP A 321 -0.965 -2.509 -39.354 1.00 97.33 O ATOM 2182 N PRO A 322 1.877 1.946 -37.792 1.00 91.01 N ATOM 2183 CA PRO A 322 2.069 3.392 -37.944 1.00 88.49 C ATOM 2184 C PRO A 322 0.859 4.022 -38.608 1.00 87.25 C ATOM 2185 O PRO A 322 0.228 3.426 -39.484 1.00 89.12 O ATOM 2186 CB PRO A 322 3.306 3.490 -38.843 1.00 94.05 C ATOM 2187 CG PRO A 322 4.041 2.214 -38.611 1.00 96.23 C ATOM 2188 CD PRO A 322 2.998 1.165 -38.345 1.00 92.28 C ATOM 2189 N TYR A 323 0.552 5.241 -38.184 1.00 81.03 N ATOM 2190 CA TYR A 323 -0.660 5.945 -38.561 1.00 78.91 C ATOM 2191 C TYR A 323 -0.268 7.360 -38.947 1.00 92.84 C ATOM 2192 O TYR A 323 0.367 8.068 -38.156 1.00 96.33 O ATOM 2193 CB TYR A 323 -1.676 5.974 -37.409 1.00 79.31 C ATOM 2194 CG TYR A 323 -2.874 6.863 -37.666 1.00 80.19 C ATOM 2195 CD1 TYR A 323 -3.736 6.592 -38.723 1.00 76.14 C ATOM 2196 CD2 TYR A 323 -3.148 7.966 -36.860 1.00 76.56 C ATOM 2197 CE1 TYR A 323 -4.830 7.394 -38.978 1.00 74.17 C ATOM 2198 CE2 TYR A 323 -4.255 8.775 -37.098 1.00 76.61 C ATOM 2199 CZ TYR A 323 -5.087 8.476 -38.166 1.00 78.77 C ATOM 2200 OH TYR A 323 -6.186 9.253 -38.444 1.00 81.18 O ATOM 2201 N ASP A 324 -0.656 7.766 -40.153 1.00 87.90 N ATOM 2202 CA ASP A 324 -0.255 9.040 -40.731 1.00 86.04 C ATOM 2203 C ASP A 324 -1.225 10.126 -40.275 1.00 93.24 C ATOM 2204 O ASP A 324 -2.411 10.099 -40.629 1.00 94.11 O ATOM 2205 CB ASP A 324 -0.215 8.923 -42.253 1.00 97.28 C ATOM 2206 CG ASP A 324 0.293 10.184 -42.931 1.00101.91 C ATOM 2207 OD1 ASP A 324 0.603 11.172 -42.233 1.00100.12 O ATOM 2208 OD2 ASP A 324 0.372 10.185 -44.184 1.00114.68 O ATOM 2209 N GLN A 325 -0.704 11.096 -39.507 1.00 94.57 N ATOM 2210 CA GLN A 325 -1.429 12.285 -39.070 1.00 91.07 C ATOM 2211 C GLN A 325 -0.971 13.551 -39.801 1.00 92.92 C ATOM 2212 O GLN A 325 -1.087 14.651 -39.258 1.00 91.79 O ATOM 2213 CB GLN A 325 -1.272 12.488 -37.560 1.00 89.00 C ATOM 2214 CG GLN A 325 -1.731 11.324 -36.684 1.00 83.54 C ATOM 2215 CD GLN A 325 -1.592 11.597 -35.183 1.00 82.25 C ATOM 2216 OE1 GLN A 325 -0.790 10.951 -34.502 1.00 81.72 O ATOM 2217 NE2 GLN A 325 -2.387 12.535 -34.658 1.00 82.89 N ATOM 2218 N SER A 326 -0.455 13.426 -41.029 1.00 96.64 N ATOM 2219 CA SER A 326 0.148 14.586 -41.688 1.00 91.43 C ATOM 2220 C SER A 326 -0.873 15.689 -41.942 1.00 91.71 C ATOM 2221 O SER A 326 -0.552 16.877 -41.848 1.00 91.75 O ATOM 2222 CB SER A 326 0.775 14.170 -43.006 1.00 98.59 C ATOM 2223 OG SER A 326 -0.264 13.975 -43.944 1.00106.30 O ATOM 2224 N PHE A 327 -2.099 15.315 -42.292 1.00 91.73 N ATOM 2225 CA PHE A 327 -3.150 16.281 -42.574 1.00 91.20 C ATOM 2226 C PHE A 327 -3.442 17.209 -41.409 1.00 93.67 C ATOM 2227 O PHE A 327 -4.155 18.202 -41.601 1.00 93.77 O ATOM 2228 CB PHE A 327 -4.431 15.546 -42.923 1.00 91.14 C ATOM 2229 CG PHE A 327 -4.989 14.779 -41.774 1.00 85.98 C ATOM 2230 CD1 PHE A 327 -5.954 15.337 -40.951 1.00 82.04 C ATOM 2231 CD2 PHE A 327 -4.508 13.512 -41.489 1.00 92.12 C ATOM 2232 CE1 PHE A 327 -6.446 14.634 -39.868 1.00 88.19 C ATOM 2233 CE2 PHE A 327 -4.998 12.787 -40.397 1.00 92.52 C ATOM 2234 CZ PHE A 327 -5.969 13.350 -39.586 1.00 86.19 C ATOM 2235 N GLU A 328 -2.961 16.889 -40.203 1.00 93.36 N ATOM 2236 CA GLU A 328 -3.366 17.645 -39.024 1.00 93.03 C ATOM 2237 C GLU A 328 -2.859 19.078 -39.088 1.00 97.28 C ATOM 2238 O GLU A 328 -3.592 20.016 -38.747 1.00 95.02 O ATOM 2239 CB GLU A 328 -2.858 16.943 -37.758 1.00 92.01 C ATOM 2240 CG GLU A 328 -3.540 15.622 -37.447 1.00 85.48 C ATOM 2241 CD GLU A 328 -4.920 15.776 -36.809 1.00 82.68 C ATOM 2242 OE1 GLU A 328 -5.475 16.905 -36.777 1.00 79.24 O ATOM 2243 OE2 GLU A 328 -5.466 14.744 -36.360 1.00 83.64 O ATOM 2244 N SER A 329 -1.609 19.258 -39.521 1.00101.21 N ATOM 2245 CA SER A 329 -0.993 20.565 -39.709 1.00103.89 C ATOM 2246 C SER A 329 -1.467 21.259 -40.980 1.00101.14 C ATOM 2247 O SER A 329 -1.108 22.422 -41.209 1.00 99.99 O ATOM 2248 CB SER A 329 0.536 20.421 -39.728 1.00102.68 C ATOM 2249 OG SER A 329 0.968 19.515 -40.737 1.00 91.84 O ATOM 2250 N ARG A 330 -2.282 20.582 -41.781 1.00101.44 N ATOM 2251 CA ARG A 330 -2.637 21.039 -43.110 1.00104.54 C ATOM 2252 C ARG A 330 -3.887 21.904 -43.073 1.00105.41 C ATOM 2253 O ARG A 330 -4.840 21.626 -42.339 1.00104.69 O ATOM 2254 CB ARG A 330 -2.853 19.843 -44.035 1.00101.77 C ATOM 2255 CG ARG A 330 -1.605 19.043 -44.323 1.00102.60 C ATOM 2256 CD ARG A 330 -1.561 18.637 -45.785 1.00108.44 C ATOM 2257 NE ARG A 330 -0.655 19.486 -46.559 1.00121.30 N ATOM 2258 CZ ARG A 330 -1.035 20.510 -47.316 1.00119.21 C ATOM 2259 NH1 ARG A 330 -2.302 20.860 -47.412 1.00117.44 N ATOM 2260 NH2 ARG A 330 -0.109 21.195 -47.975 1.00117.04 N ATOM 2261 N ASP A 331 -3.871 22.959 -43.872 1.00104.13 N ATOM 2262 CA ASP A 331 -4.962 23.919 -43.909 1.00111.77 C ATOM 2263 C ASP A 331 -5.504 23.856 -45.332 1.00119.06 C ATOM 2264 O ASP A 331 -4.937 24.472 -46.234 1.00125.89 O ATOM 2265 CB ASP A 331 -4.458 25.325 -43.513 1.00113.33 C ATOM 2266 CG ASP A 331 -5.566 26.229 -43.031 1.00114.02 C ATOM 2267 N LEU A 332 -6.577 23.088 -45.545 1.00116.53 N ATOM 2268 CA LEU A 332 -7.143 22.885 -46.880 1.00112.37 C ATOM 2269 C LEU A 332 -8.600 23.308 -46.836 1.00111.35 C ATOM 2270 O LEU A 332 -9.158 23.592 -45.768 1.00112.42 O ATOM 2271 CB LEU A 332 -7.074 21.420 -47.352 1.00111.05 C ATOM 2272 CG LEU A 332 -5.676 20.881 -47.597 1.00116.24 C ATOM 2273 CD1 LEU A 332 -5.235 20.599 -46.206 1.00113.71 C ATOM 2274 CD2 LEU A 332 -5.631 19.579 -48.347 1.00108.98 C ATOM 2275 N LEU A 333 -9.226 23.319 -48.005 1.00108.60 N ATOM 2276 CA LEU A 333 -10.607 23.760 -48.081 1.00111.30 C ATOM 2277 C LEU A 333 -11.567 22.620 -47.764 1.00107.22 C ATOM 2278 O LEU A 333 -11.244 21.442 -47.920 1.00101.46 O ATOM 2279 CB LEU A 333 -10.906 24.316 -49.476 1.00115.53 C ATOM 2280 N ILE A 334 -12.774 22.996 -47.324 1.00108.19 N ATOM 2281 CA ILE A 334 -13.748 21.998 -46.892 1.00102.88 C ATOM 2282 C ILE A 334 -14.044 21.030 -48.019 1.00100.61 C ATOM 2283 O ILE A 334 -14.276 19.841 -47.780 1.00100.00 O ATOM 2284 CB ILE A 334 -15.048 22.650 -46.367 1.00105.64 C ATOM 2285 CG1 ILE A 334 -15.883 23.232 -47.512 1.00103.85 C ATOM 2286 CG2 ILE A 334 -14.748 23.697 -45.285 1.00102.41 C ATOM 2287 CD1 ILE A 334 -16.998 22.299 -47.974 1.00101.67 C ATOM 2288 N ASP A 335 -14.033 21.511 -49.261 1.00104.17 N ATOM 2289 CA ASP A 335 -14.282 20.624 -50.385 1.00101.96 C ATOM 2290 C ASP A 335 -13.154 19.617 -50.549 1.00101.01 C ATOM 2291 O ASP A 335 -13.377 18.516 -51.062 1.00103.37 O ATOM 2292 CB ASP A 335 -14.475 21.437 -51.666 1.00102.55 C ATOM 2293 N GLU A 336 -11.940 19.966 -50.130 1.00101.61 N ATOM 2294 CA GLU A 336 -10.876 18.976 -50.186 1.00 99.88 C ATOM 2295 C GLU A 336 -10.956 18.038 -48.986 1.00103.13 C ATOM 2296 O GLU A 336 -10.752 16.823 -49.126 1.00 96.26 O ATOM 2297 CB GLU A 336 -9.513 19.660 -50.259 1.00 98.90 C ATOM 2298 CG GLU A 336 -8.362 18.695 -50.434 1.00103.17 C ATOM 2299 CD GLU A 336 -7.162 19.329 -51.110 1.00109.51 C ATOM 2300 OE1 GLU A 336 -6.206 18.578 -51.418 1.00110.37 O ATOM 2301 OE2 GLU A 336 -7.151 20.571 -51.287 1.00111.97 O ATOM 2302 N TRP A 337 -11.270 18.585 -47.806 1.00105.26 N ATOM 2303 CA TRP A 337 -11.559 17.733 -46.664 1.00 96.93 C ATOM 2304 C TRP A 337 -12.688 16.762 -46.995 1.00 95.03 C ATOM 2305 O TRP A 337 -12.570 15.562 -46.727 1.00 92.85 O ATOM 2306 CB TRP A 337 -11.904 18.573 -45.432 1.00 94.62 C ATOM 2307 CG TRP A 337 -10.766 19.353 -44.767 1.00 98.11 C ATOM 2308 CD1 TRP A 337 -10.755 20.692 -44.497 1.00103.04 C ATOM 2309 CD2 TRP A 337 -9.517 18.838 -44.260 1.00 95.49 C ATOM 2310 NE1 TRP A 337 -9.587 21.045 -43.866 1.00101.64 N ATOM 2311 CE2 TRP A 337 -8.806 19.931 -43.719 1.00 95.40 C ATOM 2312 CE3 TRP A 337 -8.932 17.566 -44.216 1.00 93.53 C ATOM 2313 CZ2 TRP A 337 -7.545 19.794 -43.147 1.00 99.91 C ATOM 2314 CZ3 TRP A 337 -7.673 17.432 -43.649 1.00 90.69 C ATOM 2315 CH2 TRP A 337 -6.995 18.540 -43.120 1.00100.86 C ATOM 2316 N LYS A 338 -13.761 17.252 -47.639 1.00 98.13 N ATOM 2317 CA LYS A 338 -14.891 16.394 -48.013 1.00 95.12 C ATOM 2318 C LYS A 338 -14.470 15.317 -49.005 1.00 91.38 C ATOM 2319 O LYS A 338 -14.897 14.158 -48.906 1.00 82.97 O ATOM 2320 CB LYS A 338 -16.023 17.237 -48.612 1.00 96.19 C ATOM 2321 N SER A 339 -13.647 15.692 -49.982 1.00 94.07 N ATOM 2322 CA SER A 339 -13.146 14.713 -50.935 1.00 94.12 C ATOM 2323 C SER A 339 -12.234 13.707 -50.252 1.00 87.58 C ATOM 2324 O SER A 339 -12.238 12.520 -50.597 1.00 83.74 O ATOM 2325 CB SER A 339 -12.413 15.417 -52.076 1.00 86.96 C ATOM 2326 OG SER A 339 -12.015 14.470 -53.052 1.00 92.72 O ATOM 2327 N LEU A 340 -11.438 14.168 -49.291 1.00 92.48 N ATOM 2328 CA LEU A 340 -10.603 13.245 -48.532 1.00 92.52 C ATOM 2329 C LEU A 340 -11.454 12.247 -47.743 1.00 79.73 C ATOM 2330 O LEU A 340 -11.195 11.040 -47.790 1.00 75.20 O ATOM 2331 CB LEU A 340 -9.651 14.039 -47.635 1.00 91.51 C ATOM 2332 CG LEU A 340 -8.514 14.659 -48.464 1.00 89.40 C ATOM 2333 N THR A 341 -12.509 12.715 -47.065 1.00 73.16 N ATOM 2334 CA THR A 341 -13.380 11.759 -46.385 1.00 80.38 C ATOM 2335 C THR A 341 -14.067 10.827 -47.386 1.00 80.44 C ATOM 2336 O THR A 341 -14.047 9.601 -47.215 1.00 77.06 O ATOM 2337 CB THR A 341 -14.413 12.459 -45.494 1.00 80.91 C ATOM 2338 OG1 THR A 341 -15.580 12.789 -46.240 1.00 91.70 O ATOM 2339 CG2 THR A 341 -13.866 13.707 -44.862 1.00 86.13 C ATOM 2340 N TYR A 342 -14.666 11.378 -48.447 1.00 84.71 N ATOM 2341 CA TYR A 342 -15.335 10.512 -49.408 1.00 80.27 C ATOM 2342 C TYR A 342 -14.375 9.464 -49.935 1.00 77.50 C ATOM 2343 O TYR A 342 -14.731 8.287 -50.053 1.00 76.41 O ATOM 2344 CB TYR A 342 -15.919 11.325 -50.551 1.00 88.81 C ATOM 2345 CG TYR A 342 -16.862 10.530 -51.417 1.00 90.54 C ATOM 2346 CD1 TYR A 342 -18.022 9.970 -50.896 1.00 92.80 C ATOM 2347 CD2 TYR A 342 -16.584 10.321 -52.754 1.00 90.54 C ATOM 2348 CE1 TYR A 342 -18.890 9.232 -51.703 1.00 95.43 C ATOM 2349 CE2 TYR A 342 -17.437 9.597 -53.560 1.00 93.27 C ATOM 2350 CZ TYR A 342 -18.582 9.048 -53.039 1.00 96.32 C ATOM 2351 OH TYR A 342 -19.397 8.320 -53.887 1.00 98.16 O ATOM 2352 N ASP A 343 -13.132 9.864 -50.192 1.00 78.39 N ATOM 2353 CA ASP A 343 -12.106 8.893 -50.552 1.00 84.38 C ATOM 2354 C ASP A 343 -12.001 7.794 -49.508 1.00 81.00 C ATOM 2355 O ASP A 343 -11.937 6.604 -49.856 1.00 76.88 O ATOM 2356 CB ASP A 343 -10.759 9.591 -50.711 1.00 94.52 C ATOM 2357 CG ASP A 343 -10.709 10.523 -51.914 1.00 99.31 C ATOM 2358 OD1 ASP A 343 -11.549 10.397 -52.849 1.00101.94 O ATOM 2359 OD2 ASP A 343 -9.818 11.397 -51.904 1.00102.92 O ATOM 2360 N GLU A 344 -11.969 8.175 -48.222 1.00 73.96 N ATOM 2361 CA GLU A 344 -11.922 7.178 -47.159 1.00 74.19 C ATOM 2362 C GLU A 344 -13.185 6.322 -47.130 1.00 66.96 C ATOM 2363 O GLU A 344 -13.092 5.116 -46.963 1.00 67.95 O ATOM 2364 CB GLU A 344 -11.710 7.878 -45.786 1.00 74.83 C ATOM 2365 CG GLU A 344 -10.338 8.543 -45.550 1.00 68.27 C ATOM 2366 CD GLU A 344 -9.239 7.535 -45.616 1.00 68.02 C ATOM 2367 OE1 GLU A 344 -9.580 6.403 -45.284 1.00 71.13 O ATOM 2368 OE2 GLU A 344 -8.075 7.836 -45.982 1.00 74.87 O ATOM 2369 N VAL A 345 -14.361 6.924 -47.268 1.00 64.32 N ATOM 2370 CA VAL A 345 -15.593 6.146 -47.315 1.00 65.58 C ATOM 2371 C VAL A 345 -15.541 5.111 -48.437 1.00 76.26 C ATOM 2372 O VAL A 345 -15.802 3.918 -48.219 1.00 78.29 O ATOM 2373 CB VAL A 345 -16.807 7.067 -47.500 1.00 76.00 C ATOM 2374 CG1 VAL A 345 -18.040 6.224 -47.792 1.00 76.28 C ATOM 2375 CG2 VAL A 345 -16.997 7.991 -46.299 1.00 62.16 C ATOM 2376 N ILE A 346 -15.210 5.561 -49.656 1.00 73.59 N ATOM 2377 CA ILE A 346 -15.154 4.693 -50.832 1.00 67.91 C ATOM 2378 C ILE A 346 -14.177 3.552 -50.617 1.00 71.67 C ATOM 2379 O ILE A 346 -14.456 2.399 -50.950 1.00 75.56 O ATOM 2380 CB ILE A 346 -14.751 5.512 -52.076 1.00 76.43 C ATOM 2381 CG1 ILE A 346 -15.898 6.332 -52.649 1.00 74.55 C ATOM 2382 CG2 ILE A 346 -14.121 4.650 -53.166 1.00 81.96 C ATOM 2383 CD1 ILE A 346 -15.413 7.072 -53.882 1.00 86.04 C ATOM 2384 N SER A 347 -12.994 3.861 -50.115 1.00 73.12 N ATOM 2385 CA SER A 347 -11.949 2.850 -50.033 1.00 73.04 C ATOM 2386 C SER A 347 -12.173 1.840 -48.913 1.00 80.78 C ATOM 2387 O SER A 347 -11.310 0.979 -48.711 1.00 86.28 O ATOM 2388 CB SER A 347 -10.579 3.504 -49.861 1.00 73.89 C ATOM 2389 OG SER A 347 -10.616 4.555 -48.911 1.00 78.32 O ATOM 2390 N PHE A 348 -13.295 1.919 -48.191 1.00 78.82 N ATOM 2391 CA PHE A 348 -13.464 1.100 -46.999 1.00 82.17 C ATOM 2392 C PHE A 348 -13.568 -0.375 -47.362 1.00 82.77 C ATOM 2393 O PHE A 348 -14.352 -0.756 -48.237 1.00 75.26 O ATOM 2394 CB PHE A 348 -14.702 1.526 -46.221 1.00 81.61 C ATOM 2395 CG PHE A 348 -15.004 0.640 -45.057 1.00 79.79 C ATOM 2396 CD1 PHE A 348 -16.006 -0.303 -45.134 1.00 85.58 C ATOM 2397 CD2 PHE A 348 -14.268 0.730 -43.893 1.00 76.83 C ATOM 2398 CE1 PHE A 348 -16.279 -1.122 -44.067 1.00 83.66 C ATOM 2399 CE2 PHE A 348 -14.530 -0.087 -42.835 1.00 71.69 C ATOM 2400 CZ PHE A 348 -15.536 -1.013 -42.916 1.00 79.36 C ATOM 2401 N VAL A 349 -12.779 -1.192 -46.672 1.00 80.64 N ATOM 2402 CA VAL A 349 -12.729 -2.638 -46.839 1.00 86.71 C ATOM 2403 C VAL A 349 -13.284 -3.271 -45.560 1.00 89.64 C ATOM 2404 O VAL A 349 -12.613 -3.249 -44.516 1.00 87.79 O ATOM 2405 CB VAL A 349 -11.296 -3.108 -47.128 1.00 83.14 C ATOM 2406 N PRO A 350 -14.495 -3.833 -45.586 1.00 93.80 N ATOM 2407 CA PRO A 350 -15.040 -4.446 -44.373 1.00 91.81 C ATOM 2408 C PRO A 350 -14.159 -5.566 -43.891 1.00 92.56 C ATOM 2409 O PRO A 350 -13.396 -6.175 -44.672 1.00 96.25 O ATOM 2410 CB PRO A 350 -16.415 -4.960 -44.832 1.00 92.10 C ATOM 2411 CG PRO A 350 -16.776 -4.054 -45.984 1.00 89.36 C ATOM 2412 CD PRO A 350 -15.470 -3.818 -46.689 1.00 85.37 C ATOM 2413 N PRO A 351 -14.202 -5.884 -42.599 1.00 93.95 N ATOM 2414 CA PRO A 351 -13.319 -6.914 -42.036 1.00102.62 C ATOM 2415 C PRO A 351 -13.759 -8.312 -42.432 1.00104.19 C ATOM 2416 O PRO A 351 -14.864 -8.503 -42.961 1.00105.12 O ATOM 2417 CB PRO A 351 -13.452 -6.697 -40.522 1.00100.86 C ATOM 2418 CG PRO A 351 -14.791 -6.060 -40.362 1.00 91.22 C ATOM 2419 CD PRO A 351 -14.969 -5.183 -41.557 1.00 92.10 C ATOM 2420 N PRO A 352 -12.900 -9.319 -42.205 1.00109.21 N ATOM 2421 CA PRO A 352 -13.267 -10.719 -42.509 1.00115.53 C ATOM 2422 C PRO A 352 -14.562 -11.193 -41.852 1.00116.18 C ATOM 2423 O PRO A 352 -14.636 -11.289 -40.620 1.00113.99 O ATOM 2424 CB PRO A 352 -12.076 -11.519 -41.959 1.00119.49 C ATOM 2425 CG PRO A 352 -10.944 -10.541 -41.816 1.00114.85 C ATOM 2426 CD PRO A 352 -11.482 -9.157 -41.820 1.00106.76 C ATOM 2427 N LEU A 353 -15.576 -11.525 -42.649 1.00115.83 N ATOM 2428 CA LEU A 353 -16.834 -12.045 -42.094 1.00116.36 C ATOM 2429 C LEU A 353 -16.695 -13.500 -41.638 1.00116.05 C ATOM 2430 O LEU A 353 -16.798 -13.806 -40.446 1.00113.09 O ATOM 2431 CB LEU A 353 -17.962 -11.926 -43.124 1.00110.00 C TER 2432 LEU A 353 ATOM 2433 N ARG B 384 -10.012 12.996 3.383 1.00108.20 N ATOM 2434 CA ARG B 384 -11.055 11.981 3.370 1.00106.31 C ATOM 2435 C ARG B 384 -10.484 10.666 2.901 1.00109.93 C ATOM 2436 O ARG B 384 -9.597 10.632 2.047 1.00111.29 O ATOM 2437 CB ARG B 384 -12.224 12.387 2.467 1.00110.58 C ATOM 2438 N VAL B 385 -11.001 9.582 3.458 1.00112.06 N ATOM 2439 CA VAL B 385 -10.652 8.233 3.032 1.00107.28 C ATOM 2440 C VAL B 385 -11.833 7.660 2.268 1.00102.74 C ATOM 2441 O VAL B 385 -12.991 8.043 2.473 1.00102.26 O ATOM 2442 CB VAL B 385 -10.267 7.321 4.217 1.00107.76 C ATOM 2443 CG1 VAL B 385 -9.162 7.963 5.039 1.00108.91 C ATOM 2444 CG2 VAL B 385 -11.484 7.043 5.078 1.00101.99 C ATOM 2445 N TYR B 386 -11.528 6.749 1.359 1.00102.69 N ATOM 2446 CA TYR B 386 -12.537 6.172 0.479 1.00107.85 C ATOM 2447 C TYR B 386 -12.344 4.668 0.470 1.00103.06 C ATOM 2448 O TYR B 386 -11.353 4.172 -0.093 1.00100.86 O ATOM 2449 CB TYR B 386 -12.458 6.778 -0.923 1.00103.41 C ATOM 2450 CG TYR B 386 -12.847 8.249 -0.944 1.00108.32 C ATOM 2451 CD1 TYR B 386 -14.027 8.675 -0.331 1.00112.39 C ATOM 2452 CD2 TYR B 386 -12.042 9.210 -1.551 1.00104.97 C ATOM 2453 CE1 TYR B 386 -14.393 10.010 -0.331 1.00113.75 C ATOM 2454 CE2 TYR B 386 -12.405 10.555 -1.557 1.00100.86 C ATOM 2455 CZ TYR B 386 -13.585 10.944 -0.940 1.00110.85 C ATOM 2456 OH TYR B 386 -13.976 12.263 -0.916 1.00115.36 O ATOM 2457 N PRO B 387 -13.217 3.930 1.135 1.00105.04 N ATOM 2458 CA PRO B 387 -13.119 2.471 1.157 1.00108.44 C ATOM 2459 C PRO B 387 -13.815 1.842 -0.040 1.00102.65 C ATOM 2460 O PRO B 387 -14.725 2.412 -0.645 1.00102.81 O ATOM 2461 CB PRO B 387 -13.846 2.111 2.458 1.00109.48 C ATOM 2462 CG PRO B 387 -14.914 3.170 2.543 1.00108.03 C ATOM 2463 CD PRO B 387 -14.284 4.431 2.013 1.00105.28 C ATOM 2464 N VAL B 388 -13.378 0.627 -0.354 1.00104.01 N ATOM 2465 CA VAL B 388 -13.831 -0.059 -1.554 1.00 96.62 C ATOM 2466 C VAL B 388 -15.286 -0.481 -1.412 1.00101.62 C ATOM 2467 O VAL B 388 -15.767 -0.781 -0.312 1.00111.15 O ATOM 2468 CB VAL B 388 -12.927 -1.274 -1.810 1.00103.02 C ATOM 2469 CG1 VAL B 388 -13.007 -1.712 -3.269 1.00104.75 C ATOM 2470 CG2 VAL B 388 -11.519 -0.941 -1.403 1.00104.46 C ATOM 2471 N SER B 389 -15.993 -0.524 -2.545 1.00100.25 N ATOM 2472 CA SER B 389 -17.389 -0.960 -2.539 1.00104.97 C ATOM 2473 C SER B 389 -17.545 -2.332 -1.895 1.00102.63 C ATOM 2474 O SER B 389 -18.426 -2.538 -1.055 1.00 94.05 O ATOM 2475 CB SER B 389 -17.948 -0.954 -3.960 1.00 91.90 C ATOM 2476 OG SER B 389 -18.174 0.369 -4.408 1.00 99.86 O ATOM 2477 N VAL B 390 -16.708 -3.276 -2.294 1.00 98.53 N ATOM 2478 CA VAL B 390 -16.632 -4.594 -1.683 1.00105.48 C ATOM 2479 C VAL B 390 -15.212 -4.761 -1.158 1.00111.84 C ATOM 2480 O VAL B 390 -14.245 -4.659 -1.920 1.00109.51 O ATOM 2481 CB VAL B 390 -17.036 -5.740 -2.631 1.00100.33 C ATOM 2482 CG1 VAL B 390 -18.283 -5.362 -3.414 1.00 95.49 C ATOM 2483 CG2 VAL B 390 -15.919 -6.180 -3.564 1.00 96.75 C ATOM 2484 N PRO B 391 -15.041 -4.937 0.149 1.00111.68 N ATOM 2485 CA PRO B 391 -13.695 -5.005 0.727 1.00108.70 C ATOM 2486 C PRO B 391 -12.894 -6.135 0.105 1.00111.89 C ATOM 2487 O PRO B 391 -13.433 -7.184 -0.251 1.00111.97 O ATOM 2488 CB PRO B 391 -13.968 -5.255 2.213 1.00113.77 C ATOM 2489 CG PRO B 391 -15.412 -5.717 2.260 1.00116.78 C ATOM 2490 CD PRO B 391 -16.097 -5.011 1.167 1.00105.52 C ATOM 2491 N TYR B 392 -11.597 -5.897 -0.043 1.00111.43 N ATOM 2492 CA TYR B 392 -10.737 -6.875 -0.683 1.00115.07 C ATOM 2493 C TYR B 392 -10.726 -8.160 0.121 1.00120.25 C ATOM 2494 O TYR B 392 -10.592 -8.143 1.350 1.00126.12 O ATOM 2495 CB TYR B 392 -9.319 -6.339 -0.833 1.00113.31 C ATOM 2496 CG TYR B 392 -8.334 -7.349 -1.385 1.00116.59 C ATOM 2497 CD1 TYR B 392 -7.221 -7.733 -0.652 1.00121.37 C ATOM 2498 CD2 TYR B 392 -8.521 -7.924 -2.639 1.00118.63 C ATOM 2499 CE1 TYR B 392 -6.314 -8.647 -1.156 1.00121.87 C ATOM 2500 CE2 TYR B 392 -7.619 -8.849 -3.146 1.00116.69 C ATOM 2501 CZ TYR B 392 -6.520 -9.204 -2.398 1.00116.39 C ATOM 2502 OH TYR B 392 -5.610 -10.116 -2.868 1.00113.94 O ATOM 2503 N SER B 393 -10.882 -9.275 -0.582 1.00121.65 N ATOM 2504 CA SER B 393 -10.824 -10.608 -0.004 1.00126.83 C ATOM 2505 C SER B 393 -9.593 -11.330 -0.537 1.00129.18 C ATOM 2506 O SER B 393 -9.315 -11.293 -1.741 1.00126.71 O ATOM 2507 CB SER B 393 -12.088 -11.400 -0.341 1.00126.73 C ATOM 2508 N SER B 394 -8.856 -11.980 0.358 1.00128.36 N ATOM 2509 CA SER B 394 -7.624 -12.662 -0.030 1.00129.91 C ATOM 2510 C SER B 394 -7.692 -14.161 0.250 1.00131.83 C ATOM 2511 O SER B 394 -6.954 -14.948 -0.344 1.00131.36 O ATOM 2512 CB SER B 394 -6.431 -12.052 0.701 1.00126.34 C ATOM 2513 OG SER B 394 -6.597 -10.653 0.847 1.00119.23 O ATOM 2514 N VAL B 403 -15.576 -17.420 -11.056 1.00123.53 N ATOM 2515 CA VAL B 403 -14.239 -16.962 -11.405 1.00124.45 C ATOM 2516 C VAL B 403 -14.223 -16.402 -12.820 1.00126.86 C ATOM 2517 O VAL B 403 -13.176 -16.355 -13.464 1.00127.59 O ATOM 2518 CB VAL B 403 -13.203 -18.087 -11.259 1.00123.96 C ATOM 2519 N THR B 404 -15.396 -15.995 -13.305 1.00123.89 N ATOM 2520 CA THR B 404 -15.533 -15.268 -14.561 1.00116.80 C ATOM 2521 C THR B 404 -16.465 -14.086 -14.326 1.00113.95 C ATOM 2522 O THR B 404 -17.447 -14.201 -13.581 1.00112.14 O ATOM 2523 CB THR B 404 -16.043 -16.179 -15.711 1.00118.36 C ATOM 2524 OG1 THR B 404 -15.747 -15.571 -16.978 1.00120.25 O ATOM 2525 CG2 THR B 404 -17.544 -16.444 -15.609 1.00117.20 C ATOM 2526 N LEU B 405 -16.136 -12.940 -14.930 1.00108.26 N ATOM 2527 CA LEU B 405 -16.728 -11.667 -14.520 1.00101.87 C ATOM 2528 C LEU B 405 -17.944 -11.310 -15.377 1.00 91.75 C ATOM 2529 O LEU B 405 -18.060 -11.741 -16.525 1.00 91.53 O ATOM 2530 CB LEU B 405 -15.681 -10.542 -14.583 1.00 94.02 C ATOM 2531 CG LEU B 405 -14.424 -10.595 -13.700 1.00 85.20 C ATOM 2532 N SER B 406 -18.864 -10.527 -14.800 1.00 92.14 N ATOM 2533 CA SER B 406 -20.060 -10.093 -15.525 1.00 90.59 C ATOM 2534 C SER B 406 -20.612 -8.804 -14.912 1.00 88.20 C ATOM 2535 O SER B 406 -20.354 -8.507 -13.748 1.00 93.48 O ATOM 2536 CB SER B 406 -21.130 -11.191 -15.542 1.00 91.41 C ATOM 2537 OG SER B 406 -22.040 -11.064 -14.456 1.00 92.48 O ATOM 2538 N LEU B 407 -21.394 -8.041 -15.698 1.00 82.46 N ATOM 2539 CA LEU B 407 -22.086 -6.857 -15.189 1.00 88.95 C ATOM 2540 C LEU B 407 -23.555 -6.913 -15.560 1.00 88.02 C ATOM 2541 O LEU B 407 -23.922 -7.523 -16.567 1.00 89.39 O ATOM 2542 CB LEU B 407 -21.537 -5.526 -15.757 1.00 85.74 C ATOM 2543 CG LEU B 407 -20.109 -4.999 -15.617 1.00 83.53 C ATOM 2544 CD1 LEU B 407 -19.705 -4.890 -14.210 1.00 88.34 C ATOM 2545 CD2 LEU B 407 -19.177 -5.888 -16.309 1.00 89.13 C ATOM 2546 N VAL B 408 -24.417 -6.234 -14.796 1.00 86.74 N ATOM 2547 CA VAL B 408 -25.820 -6.123 -15.208 1.00 94.06 C ATOM 2548 C VAL B 408 -26.009 -4.893 -16.079 1.00 96.79 C ATOM 2549 O VAL B 408 -25.568 -3.781 -15.710 1.00 96.36 O ATOM 2550 CB VAL B 408 -26.788 -6.103 -14.008 1.00 95.68 C ATOM 2551 CG1 VAL B 408 -26.359 -5.118 -12.969 1.00 99.38 C ATOM 2552 CG2 VAL B 408 -28.182 -5.782 -14.542 1.00 96.51 C ATOM 2553 N MET B 409 -26.686 -5.087 -17.199 1.00 89.93 N ATOM 2554 CA MET B 409 -27.004 -4.042 -18.146 1.00 97.34 C ATOM 2555 C MET B 409 -28.220 -3.232 -17.688 1.00 98.36 C ATOM 2556 O MET B 409 -29.207 -3.804 -17.223 1.00101.74 O ATOM 2557 CB MET B 409 -27.290 -4.652 -19.515 1.00 90.27 C ATOM 2558 CG MET B 409 -26.093 -5.367 -20.075 1.00 89.88 C ATOM 2559 SD MET B 409 -24.629 -4.355 -19.821 1.00 93.05 S ATOM 2560 CE MET B 409 -23.859 -4.633 -21.402 1.00 79.02 C ATOM 2561 N PRO B 410 -28.175 -1.900 -17.798 1.00100.60 N ATOM 2562 CA PRO B 410 -29.384 -1.087 -17.660 1.00100.45 C ATOM 2563 C PRO B 410 -30.407 -1.373 -18.761 1.00100.94 C ATOM 2564 O PRO B 410 -30.068 -1.985 -19.784 1.00 99.58 O ATOM 2565 CB PRO B 410 -28.854 0.353 -17.775 1.00 97.62 C ATOM 2566 CG PRO B 410 -27.425 0.271 -17.373 1.00 92.86 C ATOM 2567 CD PRO B 410 -26.951 -1.085 -17.835 1.00100.23 C TER 2568 PRO B 410 HETATM 2569 CA1 SB4 A 401 -23.821 5.699 -27.146 1.00 64.67 C HETATM 2570 CA2 SB4 A 401 -24.415 6.479 -25.954 1.00 76.14 C HETATM 2571 NA3 SB4 A 401 -23.884 6.076 -24.592 1.00 63.23 N HETATM 2572 CA4 SB4 A 401 -22.383 6.119 -24.525 1.00 60.58 C HETATM 2573 CA5 SB4 A 401 -21.808 6.469 -25.916 1.00 62.26 C HETATM 2574 CA6 SB4 A 401 -22.339 5.512 -26.950 1.00 61.34 C HETATM 2575 CB1 SB4 A 401 -21.299 4.296 -32.150 1.00 64.42 C HETATM 2576 CB2 SB4 A 401 -21.034 3.725 -33.389 1.00 62.34 C HETATM 2577 CB3 SB4 A 401 -19.804 3.953 -33.973 1.00 60.73 C HETATM 2578 CB4 SB4 A 401 -18.848 4.728 -33.330 1.00 68.64 C HETATM 2579 CB5 SB4 A 401 -19.130 5.287 -32.085 1.00 63.99 C HETATM 2580 CB6 SB4 A 401 -20.349 5.053 -31.478 1.00 65.15 C HETATM 2581 FB7 SB4 A 401 -19.528 3.412 -35.173 1.00 58.15 F HETATM 2582 CC1 SB4 A 401 -20.970 2.468 -29.649 1.00 63.81 C HETATM 2583 CC2 SB4 A 401 -21.794 3.453 -29.168 1.00 65.46 C HETATM 2584 NC3 SB4 A 401 -22.853 3.024 -28.478 1.00 67.41 N HETATM 2585 CC4 SB4 A 401 -23.117 1.700 -28.309 1.00 63.57 C HETATM 2586 NC5 SB4 A 401 -22.297 0.745 -28.836 1.00 62.21 N HETATM 2587 CC6 SB4 A 401 -21.227 1.136 -29.495 1.00 57.96 C HETATM 2588 NC7 SB4 A 401 -24.304 1.320 -27.558 1.00 62.13 N HETATM 2589 ND1 SB4 A 401 -21.662 5.734 -28.267 1.00 68.13 N HETATM 2590 CD2 SB4 A 401 -21.177 6.927 -28.641 1.00 62.31 C HETATM 2591 ND3 SB4 A 401 -20.640 6.791 -29.845 1.00 66.17 N HETATM 2592 CD4 SB4 A 401 -20.799 5.523 -30.238 1.00 71.37 C HETATM 2593 CD5 SB4 A 401 -21.475 4.832 -29.234 1.00 65.90 C HETATM 2594 O HOH A 501 -12.722 9.329 -10.390 1.00 57.12 O HETATM 2595 O HOH A 502 -11.025 12.889 -27.759 1.00 60.24 O HETATM 2596 O HOH A 503 -28.075 -3.851 -47.455 1.00 77.52 O HETATM 2597 O HOH A 504 -25.193 11.976 -49.108 1.00 99.10 O HETATM 2598 O HOH A 505 -10.840 -8.207 -23.910 1.00 72.29 O HETATM 2599 O HOH A 506 -19.011 0.964 -7.748 1.00 77.97 O HETATM 2600 O HOH A 507 -25.007 0.846 -6.208 1.00 80.40 O HETATM 2601 O HOH B 501 -14.256 -13.017 -17.369 1.00 85.25 O CONECT 2569 2570 2574 CONECT 2570 2569 2571 CONECT 2571 2570 2572 CONECT 2572 2571 2573 CONECT 2573 2572 2574 CONECT 2574 2569 2573 2589 CONECT 2575 2576 2580 CONECT 2576 2575 2577 CONECT 2577 2576 2578 2581 CONECT 2578 2577 2579 CONECT 2579 2578 2580 CONECT 2580 2575 2579 2592 CONECT 2581 2577 CONECT 2582 2583 2587 CONECT 2583 2582 2584 2593 CONECT 2584 2583 2585 CONECT 2585 2584 2586 2588 CONECT 2586 2585 2587 CONECT 2587 2582 2586 CONECT 2588 2585 CONECT 2589 2574 2590 2593 CONECT 2590 2589 2591 CONECT 2591 2590 2592 CONECT 2592 2580 2591 2593 CONECT 2593 2583 2589 2592 MASTER 356 0 1 17 10 0 3 6 2599 2 25 31 END
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360aa, >1WBV_1|Chain... at 99%
1wbw
RCSB PDB
PDBbind
360aa, >1WBW_1|Chain... at 99%
1yqj
RCSB PDB
PDBbind
366aa, >1YQJ_1|Chain... at 98%
1yw2
RCSB PDB
PDBbind
360aa, >1YW2_1|Chain... at 98%
1ywr
RCSB PDB
PDBbind
360aa, >1YWR_1|Chain... at 98%
1zyj
RCSB PDB
PDBbind
360aa, >1ZYJ_1|Chain... at 99%
1zz2
RCSB PDB
PDBbind
360aa, >1ZZ2_1|Chain... at 99%
1zzl
RCSB PDB
PDBbind
351aa, >1ZZL_1|Chain... at 99%
2baj
RCSB PDB
PDBbind
365aa, >2BAJ_1|Chain... at 99%
2bak
RCSB PDB
PDBbind
365aa, >2BAK_1|Chain... at 99%
2bal
RCSB PDB
PDBbind
365aa, >2BAL_1|Chain... at 99%
2ewa
RCSB PDB
PDBbind
379aa, >2EWA_1|Chain... at 96%
2gfs
RCSB PDB
PDBbind
372aa, >2GFS_1|Chain... at 98%
2i0h
RCSB PDB
PDBbind
366aa, >2I0H_1|Chain... at 98%
2onl
RCSB PDB
PDBbind
366aa, >2ONL_1|Chains... at 98%
2oza
RCSB PDB
PDBbind
366aa, >2OZA_2|Chain... at 98%
2qd9
RCSB PDB
PDBbind
366aa, >2QD9_1|Chain... at 98%
2rg5
RCSB PDB
PDBbind
366aa, >2RG5_1|Chain... at 98%
2rg6
RCSB PDB
PDBbind
366aa, >2RG6_1|Chain... at 98%
2yis
RCSB PDB
PDBbind
359aa, >2YIS_1|Chain... at 99%
2yiw
RCSB PDB
PDBbind
359aa, >2YIW_1|Chain... at 99%
2yix
RCSB PDB
PDBbind
351aa, >2YIX_1|Chain... at 99%
2zaz
RCSB PDB
PDBbind
360aa, >2ZAZ_1|Chain... at 99%
2zb0
RCSB PDB
PDBbind
360aa, >2ZB0_1|Chain... at 99%
2zb1
RCSB PDB
PDBbind
360aa, >2ZB1_1|Chain... at 99%
3bv2
RCSB PDB
PDBbind
366aa, >3BV2_1|Chain... at 98%
3bv3
RCSB PDB
PDBbind
366aa, >3BV3_1|Chain... at 98%
3bx5
RCSB PDB
PDBbind
366aa, >3BX5_1|Chain... at 98%
3c5u
RCSB PDB
PDBbind
366aa, >3C5U_1|Chain... at 98%
3ctq
RCSB PDB
PDBbind
348aa, >3CTQ_1|Chain... at 98%
3d7z
RCSB PDB
PDBbind
360aa, >3D7Z_1|Chain... at 99%
3d83
RCSB PDB
PDBbind
360aa, >3D83_1|Chain... at 99%
3ds6
RCSB PDB
PDBbind
366aa, >3DS6_1|Chains... at 98%
3dt1
RCSB PDB
PDBbind
383aa, >3DT1_1|Chain... at 95%
3e92
RCSB PDB
PDBbind
371aa, >3E92_1|Chain... at 97%
3e93
RCSB PDB
PDBbind
371aa, >3E93_1|Chain... at 97%
3fc1
RCSB PDB
PDBbind
366aa, >3FC1_1|Chain... at 98%
3gc7
RCSB PDB
PDBbind
366aa, >3GC7_1|Chain... at 98%
3gcp
RCSB PDB
PDBbind
360aa, >3GCP_1|Chain... at 99%
3gcq
RCSB PDB
PDBbind
360aa, >3GCQ_1|Chain... at 99%
3gcs
RCSB PDB
PDBbind
360aa, >3GCS_1|Chain... at 99%
3gcu
RCSB PDB
PDBbind
360aa, >3GCU_1|Chains... at 99%
3gcv
RCSB PDB
PDBbind
360aa, >3GCV_1|Chain... at 99%
3gfe
RCSB PDB
PDBbind
366aa, >3GFE_1|Chain... at 98%
3hec
RCSB PDB
PDBbind
348aa, >3HEC_1|Chain... at 99%
3heg
RCSB PDB
PDBbind
348aa, >3HEG_1|Chain... at 99%
3hl7
RCSB PDB
PDBbind
360aa, >3HL7_1|Chain... at 99%
3hll
RCSB PDB
PDBbind
360aa, >3HLL_1|Chain... at 99%
3hp2
RCSB PDB
PDBbind
360aa, >3HP2_1|Chain... at 99%
3hp5
RCSB PDB
PDBbind
360aa, >3HP5_1|Chain... at 99%
3hrb
RCSB PDB
PDBbind
359aa, >3HRB_1|Chain... at 99%
3hub
RCSB PDB
PDBbind
360aa, >3HUB_1|Chain... at 99%
3huc
RCSB PDB
PDBbind
360aa, >3HUC_1|Chain... at 99%
3hv3
RCSB PDB
PDBbind
360aa, >3HV3_1|Chain... at 99%
3hv4
RCSB PDB
PDBbind
360aa, >3HV4_1|Chains... at 99%
3hv5
RCSB PDB
PDBbind
360aa, >3HV5_1|Chains... at 99%
3hv6
RCSB PDB
PDBbind
360aa, >3HV6_1|Chain... at 99%
3hv7
RCSB PDB
PDBbind
360aa, >3HV7_1|Chain... at 99%
3hvc
RCSB PDB
PDBbind
362aa, >3HVC_1|Chain... at 99%
3iph
RCSB PDB
PDBbind
360aa, >3IPH_1|Chain... at 99%
3itz
RCSB PDB
PDBbind
366aa, >3ITZ_1|Chain... at 98%
3iw5
RCSB PDB
PDBbind
360aa, >3IW5_1|Chain... at 99%
3iw6
RCSB PDB
PDBbind
360aa, >3IW6_1|Chain... at 99%
3iw7
RCSB PDB
PDBbind
360aa, >3IW7_1|Chain... at 99%
3iw8
RCSB PDB
PDBbind
360aa, >3IW8_1|Chain... at 99%
3k3i
RCSB PDB
PDBbind
350aa, >3K3I_1|Chain... at 98%
3k3j
RCSB PDB
PDBbind
362aa, >3K3J_1|Chain... at 99%
3kf7
RCSB PDB
PDBbind
360aa, >3KF7_1|Chain... at 99%
3l8s
RCSB PDB
PDBbind
360aa, >3L8S_1|Chain... at 99%
3l8x
RCSB PDB
PDBbind
366aa, >3L8X_1|Chain... at 98%
3lhj
RCSB PDB
PDBbind
366aa, >3LHJ_1|Chain... at 98%
3mpt
RCSB PDB
PDBbind
371aa, >3MPT_1|Chain... at 97%
3mvl
RCSB PDB
PDBbind
366aa, >3MVL_1|Chains... at 98%
3mvm
RCSB PDB
PDBbind
366aa, >3MVM_1|Chains... at 98%
3mw1
RCSB PDB
PDBbind
359aa, >3MW1_1|Chain... at 99%
3new
RCSB PDB
PDBbind
366aa, >3NEW_1|Chain... at 98%
3nnu
RCSB PDB
PDBbind
354aa, >3NNU_1|Chain... at 99%
3nnv
RCSB PDB
PDBbind
354aa, >3NNV_1|Chain... at 99%
3nnw
RCSB PDB
PDBbind
354aa, >3NNW_1|Chain... at 99%
3nnx
RCSB PDB
PDBbind
354aa, >3NNX_1|Chain... at 99%
3nww
RCSB PDB
PDBbind
366aa, >3NWW_1|Chain... at 98%
3o8p
RCSB PDB
PDBbind
360aa, >3O8P_1|Chain... at 99%
3ocg
RCSB PDB
PDBbind
366aa, >3OCG_1|Chain... at 98%
3p5k
RCSB PDB
PDBbind
366aa, >3P5K_1|Chain... at 98%
3p78
RCSB PDB
PDBbind
366aa, >3P78_1|Chain... at 98%
3p79
RCSB PDB
PDBbind
366aa, >3P79_1|Chain... at 98%
3p7a
RCSB PDB
PDBbind
366aa, >3P7A_1|Chain... at 98%
3p7b
RCSB PDB
PDBbind
366aa, >3P7B_1|Chain... at 98%
3p7c
RCSB PDB
PDBbind
366aa, >3P7C_1|Chain... at 98%
3que
RCSB PDB
PDBbind
360aa, >3QUE_1|Chain... at 99%
3rin
RCSB PDB
PDBbind
360aa, >3RIN_1|Chain... at 99%
3roc
RCSB PDB
PDBbind
360aa, >3ROC_1|Chain... at 99%
3s3i
RCSB PDB
PDBbind
349aa, >3S3I_1|Chain... at 99%
3s4q
RCSB PDB
PDBbind
366aa, >3S4Q_1|Chain... at 98%
3u8w
RCSB PDB
PDBbind
366aa, >3U8W_1|Chain... at 98%
3uvp
RCSB PDB
PDBbind
360aa, >3UVP_1|Chain... at 99%
3uvq
RCSB PDB
PDBbind
360aa, >3UVQ_1|Chain... at 99%
3zya
RCSB PDB
PDBbind
366aa, >3ZYA_1|Chain... at 98%
4aa0
RCSB PDB
PDBbind
365aa, >4AA0_1|Chain... at 99%
4aa4
RCSB PDB
PDBbind
365aa, >4AA4_1|Chain... at 99%
4aa5
RCSB PDB
PDBbind
365aa, >4AA5_1|Chain... at 99%
4aac
RCSB PDB
PDBbind
365aa, >4AAC_1|Chain... at 99%
4dli
RCSB PDB
PDBbind
360aa, >4DLI_1|Chain... at 99%
4dlj
RCSB PDB
PDBbind
360aa, >4DLJ_1|Chain... at 99%
4e6c
RCSB PDB
PDBbind
360aa, >4E6C_1|Chain... at 99%
4eh2
RCSB PDB
PDBbind
360aa, >4EH2_1|Chain... at 99%
4eh3
RCSB PDB
PDBbind
360aa, >4EH3_1|Chain... at 99%
4eh4
RCSB PDB
PDBbind
360aa, >4EH4_1|Chain... at 99%
4eh5
RCSB PDB
PDBbind
360aa, >4EH5_1|Chain... at 99%
4eh6
RCSB PDB
PDBbind
360aa, >4EH6_1|Chain... at 99%
4eh7
RCSB PDB
PDBbind
360aa, >4EH7_1|Chain... at 99%
4eh8
RCSB PDB
PDBbind
360aa, >4EH8_1|Chain... at 99%
4eh9
RCSB PDB
PDBbind
360aa, >4EH9_1|Chain... at 99%
4ehv
RCSB PDB
PDBbind
360aa, >4EHV_1|Chain... at 99%
4f9w
RCSB PDB
PDBbind
383aa, >4F9W_1|Chain... at 96%
4f9y
RCSB PDB
PDBbind
383aa, >4F9Y_1|Chain... at 96%
4kin
RCSB PDB
PDBbind
366aa, >4KIN_1|Chains... at 98%
4kip
RCSB PDB
PDBbind
366aa, >4KIP_1|Chains... at 98%
4kiq
RCSB PDB
PDBbind
366aa, >4KIQ_1|Chains... at 98%
4l8m
RCSB PDB
PDBbind
360aa, >4L8M_1|Chain... at 99%
4loo
RCSB PDB
PDBbind
361aa, >4LOO_1|Chain... at 98%
4lop
RCSB PDB
PDBbind
361aa, >4LOP_1|Chains... at 98%
4loq
RCSB PDB
PDBbind
361aa, >4LOQ_1|Chains... at 98%
4r3c
RCSB PDB
PDBbind
383aa, >4R3C_1|Chain... at 96%
5ml5
RCSB PDB
PDBbind
360aa, >5ML5_1|Chain... at 99%
5mtx
RCSB PDB
PDBbind
360aa, >5MTX_1|Chain... at 99%
5mty
RCSB PDB
PDBbind
360aa, >5MTY_1|Chain... at 99%
5mz3
RCSB PDB
PDBbind
369aa, >5MZ3_1|Chain... at 98%
5nzz
RCSB PDB
PDBbind
360aa, >5NZZ_2|Chains... at 98%
5tbe
RCSB PDB
PDBbind
360aa, >5TBE_1|Chain... at 99%
5tco
RCSB PDB
PDBbind
360aa, >5TCO_1|Chain... at 99%
5wjj
RCSB PDB
PDBbind
365aa, >5WJJ_1|Chain... at 100%
5xyx
RCSB PDB
PDBbind
380aa, >5XYX_1|Chain... at 96%
5xyy
RCSB PDB
PDBbind
380aa, >5XYY_1|Chain... at 96%
6anl
RCSB PDB
PDBbind
365aa, >6ANL_1|Chain... at 100%
6ohd
RCSB PDB
PDBbind
388aa, >6OHD_1|Chain... at 100%
6m9l
RCSB PDB
PDBbind
388aa, >6M9L_1|Chain... at 99%
6m95
RCSB PDB
PDBbind
388aa, >6M95_1|Chain... *
6hwv
RCSB PDB
PDBbind
362aa, >6HWV_1|Chain... at 99%
6hwu
RCSB PDB
PDBbind
362aa, >6HWU_1|Chain... at 99%
6sfi
RCSB PDB
PDBbind
361aa, >6SFI_1|Chain... at 98%
6sfj
RCSB PDB
PDBbind
361aa, >6SFJ_1|Chain... at 98%
6sfk
RCSB PDB
PDBbind
361aa, >6SFK_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5o90
Complex Type
Protein-Protein
PDBbind Subset
general set
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
EC.Number
E.C.2.7.11.24
Resolution
2.49(Å)
Affinity (Kd/Ki/IC50)
Kd=1.1uM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Mol. Cell. Biol. Vol. 38: pp. e00409-17
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
P47811
Q15750
Entrez Gene ID
NCBI Entrez Gene ID:
26416
10454
ASD
Information of known allosteric effects of PDB entries
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