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Related entries of code: 5ovi
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5ovhRCSB PDB    PDBbind490aa, >5OVH_1|Chain... at 100%
5ovgRCSB PDB    PDBbind490aa, >5OVG_1|Chain... at 100%
5ovfRCSB PDB    PDBbind490aa, >5OVF_1|Chain... at 100%
5oveRCSB PDB    PDBbind490aa, >5OVE_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5ovi
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSon of sevenless homolog 1
Ligand NameAXH
EC.Number E.C.-.-.-.-
Resolution 2.2(Å)
Affinity (Kd/Ki/IC50)IC50=21nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Proc. Natl. Acad. Sci. U.S.A. Vol. 116: pp. 2551-2560
Ligand Properties
Formula C25H29N4O2S
Molecular Weight 449.588
Exact Mass 449.201
No. of atoms 61
No. of bonds 64
Polar Surface Area 101.12
LOGP Value 4.81      (Computed with XLOGP3)
4.62      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 8
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q07889  
Entrez Gene IDNCBI Entrez Gene ID: 6654  
ASDInformation of known allosteric effects of PDB entries
 
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