Browse entries in the PDBbind-CN Database

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Related entries of code: 5ttf
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
3k5kRCSB PDB    PDBbind283aa, >3K5K_1|Chains... at 99%
3rjwRCSB PDB    PDBbind283aa, >3RJW_1|Chains... at 99%
4nvqRCSB PDB    PDBbind285aa, >4NVQ_1|Chains... *
5tuyRCSB PDB    PDBbind268aa, >5TUY_1|Chains... at 99%
5vscRCSB PDB    PDBbind275aa, >5VSC_1|Chains... at 100%
5vseRCSB PDB    PDBbind275aa, >5VSE_1|Chains... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
5ttgRCSB PDB    PDBbind7KZ
Entry Information
PDB ID5ttf
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameHistone-lysine N-methyltransferase EHMT2
Ligand Name7KZ
EC.Number E.C.2.1.1.-; 2.1.1.43
Resolution 1.72(Å)
Affinity (Kd/Ki/IC50)Kd=610nM
Release Year2016
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 1876-1891
Ligand Properties
Formula C17H26N5O2
Molecular Weight 332.421
Exact Mass 332.209
No. of atoms 50
No. of bonds 52
Polar Surface Area 84.91
LOGP Value 2.61      (Computed with XLOGP3)
2.93      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 7
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q96KQ7  
Entrez Gene IDNCBI Entrez Gene ID: 10919  
ASDInformation of known allosteric effects of PDB entries
 
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