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Related entries of code: 5urk
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5urjRCSB PDB    PDBbind1738aa, >5URJ_1|Chain... *
5urmRCSB PDB    PDBbind1738aa, >5URM_1|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5urk
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameSpliceosomal RNA Helicase Brr2
Ligand Name8LP
EC.Number E.C.-.-.-.-
Resolution 2.95(Å)
Affinity (Kd/Ki/IC50)IC50=0.79uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 5759-5771
Ligand Properties
Formula C27H23N3O3
Molecular Weight 437.490
Exact Mass 437.174
No. of atoms 56
No. of bonds 60
Polar Surface Area 62.21
LOGP Value 3.51      (Computed with XLOGP3)
4.40      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O75643  
Entrez Gene IDNCBI Entrez Gene ID: 23020  
ASDInformation of known allosteric effects of PDB entries
 
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