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Related entries of code: 5vc3
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1x8bRCSB PDB    PDBbind289aa, >1X8B_1|Chain... *
2in6RCSB PDB    PDBbind287aa, >2IN6_1|Chain... at 99%
2io6RCSB PDB    PDBbind287aa, >2IO6_1|Chain... at 99%
3bi6RCSB PDB    PDBbind287aa, >3BI6_1|Chain... at 99%
3bizRCSB PDB    PDBbind287aa, >3BIZ_1|Chain... at 99%
5v5yRCSB PDB    PDBbind289aa, >5V5Y_1|Chain... at 99%
5vc4RCSB PDB    PDBbind289aa, >5VC4_1|Chain... at 99%
5vc5RCSB PDB    PDBbind289aa, >5VC5_1|Chain... at 99%
5vc6RCSB PDB    PDBbind289aa, >5VC6_1|Chain... at 99%
5vd2RCSB PDB    PDBbind289aa, >5VD2_1|Chain... at 99%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3ue4RCSB PDB    PDBbindDB8
6op9RCSB PDB    PDBbindDB8
4qmnRCSB PDB    PDBbindDB8
5i9xRCSB PDB    PDBbindDB8
5vcyRCSB PDB    PDBbindDB8
Entry Information
PDB ID5vc3
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameWee1-like protein kinase
Ligand NameDB8
EC.Number E.C.-.-.-.-
Resolution 1.97(Å)
Affinity (Kd/Ki/IC50)Kd=77.5nM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2017) J. Med. Chem. Vol. 60: pp. 7863-7875
Ligand Properties
Formula C26H31Cl2N5O3
Molecular Weight 532.462
Exact Mass 531.180
No. of atoms 67
No. of bonds 70
Polar Surface Area 85.28
LOGP Value 5.38      (Computed with XLOGP3)
5.57      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P30291  
Entrez Gene IDNCBI Entrez Gene ID: 7465  
ASDInformation of known allosteric effects of PDB entries
 
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