Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 28-APR-17 5VMV TITLE KAISO (ZBTB33) ZINC FINGER DNA BINDING DOMAIN IN COMPLEX WITH ITS TITLE 2 DOUBLE CPG-METHYLATED DNA CONSENSUS BINDING SITE COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTIONAL REGULATOR KAISO; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: RESIDUES 471-604; COMPND 5 SYNONYM: ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 33; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*TP*GP*CP*TP*TP*CP*TP*(5CM)P*GP*(5CM) COMPND 9 P*GP*AP*GP*AP*AP*GP*CP*A)-3'); COMPND 10 CHAIN: D, E; COMPND 11 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: ZBTB33, KAISO, ZNF348; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21(DE3); SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) [DNAY]; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET21D; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 14 ORGANISM_TAXID: 9606 KEYWDS DNA METHYLATION, ZINC FINGER, TRANSCRIPTIONAL REGULATOR, KEYWDS 2 TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR E.N.NIKOLOVA,R.L.STANFIELD,M.A.MARTINEZ-YAMOUT,H.J.DYSON,P.E.WRIGHT REVDAT 2 25-APR-18 5VMV 1 JRNL REVDAT 1 04-APR-18 5VMV 0 JRNL AUTH E.N.NIKOLOVA,R.L.STANFIELD,H.J.DYSON,P.E.WRIGHT JRNL TITL CH···O HYDROGEN BONDS MEDIATE HIGHLY SPECIFIC JRNL TITL 2 RECOGNITION OF METHYLATED CPG SITES BY THE ZINC FINGER JRNL TITL 3 PROTEIN KAISO. JRNL REF BIOCHEMISTRY V. 57 2109 2018 JRNL REFN ISSN 1520-4995 JRNL PMID 29546986 JRNL DOI 10.1021/ACS.BIOCHEM.8B00065 REMARK 2 REMARK 2 RESOLUTION. 2.31 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX 1.9_1692 REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : ML REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.31 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 45.44 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.350 REMARK 3 COMPLETENESS FOR RANGE (%) : 90.7 REMARK 3 NUMBER OF REFLECTIONS : 17361 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.208 REMARK 3 R VALUE (WORKING SET) : 0.203 REMARK 3 FREE R VALUE : 0.247 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 10.010 REMARK 3 FREE R VALUE TEST SET COUNT : 1738 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 45.4518 - 5.2940 0.99 1542 172 0.2183 0.2494 REMARK 3 2 5.2940 - 4.2029 1.00 1471 163 0.1754 0.2115 REMARK 3 3 4.2029 - 3.6719 1.00 1432 159 0.1736 0.2236 REMARK 3 4 3.6719 - 3.3363 1.00 1439 161 0.1889 0.2486 REMARK 3 5 3.3363 - 3.0972 1.00 1437 159 0.2198 0.2823 REMARK 3 6 3.0972 - 2.9147 1.00 1410 156 0.2207 0.2565 REMARK 3 7 2.9147 - 2.7687 1.00 1409 157 0.2133 0.2685 REMARK 3 8 2.7687 - 2.6482 0.98 1412 157 0.2320 0.2688 REMARK 3 9 2.6482 - 2.5463 0.95 1341 149 0.2353 0.2628 REMARK 3 10 2.5463 - 2.4584 0.84 1175 131 0.2344 0.3080 REMARK 3 11 2.4584 - 2.3816 0.61 863 97 0.2323 0.2331 REMARK 3 12 2.3816 - 2.3135 0.50 692 77 0.2229 0.2967 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : FLAT BULK SOLVENT MODEL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.220 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 28.090 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : 35.35 REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.011 2116 REMARK 3 ANGLE : 1.203 3012 REMARK 3 CHIRALITY : 0.050 315 REMARK 3 PLANARITY : 0.005 221 REMARK 3 DIHEDRAL : 27.666 822 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 12 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 481 THROUGH 496 ) REMARK 3 ORIGIN FOR THE GROUP (A): 20.6940 4.8865 27.6925 REMARK 3 T TENSOR REMARK 3 T11: 0.8813 T22: 0.1874 REMARK 3 T33: 1.2898 T12: 0.0558 REMARK 3 T13: -0.0204 T23: -0.1295 REMARK 3 L TENSOR REMARK 3 L11: 0.7296 L22: 5.4921 REMARK 3 L33: 1.9339 L12: -1.7920 REMARK 3 L13: -0.6677 L23: 0.4051 REMARK 3 S TENSOR REMARK 3 S11: -0.1111 S12: -0.2972 S13: -0.6070 REMARK 3 S21: 0.3474 S22: 0.0726 S23: -0.0977 REMARK 3 S31: 0.4379 S32: 0.1881 S33: -0.3006 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 497 THROUGH 505 ) REMARK 3 ORIGIN FOR THE GROUP (A): 17.0317 9.4900 21.9111 REMARK 3 T TENSOR REMARK 3 T11: 0.7243 T22: 0.0781 REMARK 3 T33: 1.0532 T12: 0.0443 REMARK 3 T13: 0.0036 T23: -0.1634 REMARK 3 L TENSOR REMARK 3 L11: 3.8594 L22: 4.0473 REMARK 3 L33: 4.7964 L12: 2.6836 REMARK 3 L13: 2.4378 L23: 1.8570 REMARK 3 S TENSOR REMARK 3 S11: 0.0872 S12: 0.2245 S13: -0.4898 REMARK 3 S21: -0.1187 S22: 0.2012 S23: 0.2610 REMARK 3 S31: 0.5084 S32: 0.2725 S33: -0.2064 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 506 THROUGH 527 ) REMARK 3 ORIGIN FOR THE GROUP (A): 5.5258 18.7422 23.5479 REMARK 3 T TENSOR REMARK 3 T11: 0.4353 T22: 0.1909 REMARK 3 T33: 1.4447 T12: -0.1216 REMARK 3 T13: -0.0346 T23: 0.0232 REMARK 3 L TENSOR REMARK 3 L11: 0.5135 L22: 2.5373 REMARK 3 L33: 1.3688 L12: -0.5324 REMARK 3 L13: 0.6468 L23: 0.1448 REMARK 3 S TENSOR REMARK 3 S11: 0.1431 S12: -0.2746 S13: -0.7745 REMARK 3 S21: -0.0790 S22: 0.2894 S23: 1.4217 REMARK 3 S31: 0.8630 S32: -0.2982 S33: 0.0951 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 528 THROUGH 533 ) REMARK 3 ORIGIN FOR THE GROUP (A): 2.1254 24.7628 18.0569 REMARK 3 T TENSOR REMARK 3 T11: 0.5365 T22: 0.0277 REMARK 3 T33: 1.3126 T12: 0.0207 REMARK 3 T13: -0.2811 T23: -0.1432 REMARK 3 L TENSOR REMARK 3 L11: 1.0853 L22: 1.5758 REMARK 3 L33: 1.2808 L12: 1.2384 REMARK 3 L13: 0.4669 L23: 0.1242 REMARK 3 S TENSOR REMARK 3 S11: 0.1821 S12: 0.0191 S13: -0.3320 REMARK 3 S21: -0.5424 S22: -0.0075 S23: 0.8931 REMARK 3 S31: 0.3983 S32: -0.2259 S33: -0.2582 REMARK 3 TLS GROUP : 5 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 534 THROUGH 545 ) REMARK 3 ORIGIN FOR THE GROUP (A): 6.8230 31.6496 21.0907 REMARK 3 T TENSOR REMARK 3 T11: 0.3877 T22: 0.2296 REMARK 3 T33: 0.6598 T12: 0.0280 REMARK 3 T13: -0.0380 T23: -0.0815 REMARK 3 L TENSOR REMARK 3 L11: 1.5341 L22: 2.2140 REMARK 3 L33: 4.7098 L12: -1.1944 REMARK 3 L13: 0.4977 L23: -2.2913 REMARK 3 S TENSOR REMARK 3 S11: -0.1007 S12: -0.1025 S13: -0.4803 REMARK 3 S21: -0.0348 S22: 0.3776 S23: 0.3213 REMARK 3 S31: 0.0726 S32: -0.3137 S33: -0.2803 REMARK 3 TLS GROUP : 6 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 546 THROUGH 573 ) REMARK 3 ORIGIN FOR THE GROUP (A): 21.2438 41.5289 19.3166 REMARK 3 T TENSOR REMARK 3 T11: 0.2066 T22: 0.1561 REMARK 3 T33: 0.4016 T12: 0.0481 REMARK 3 T13: -0.0507 T23: 0.0046 REMARK 3 L TENSOR REMARK 3 L11: 7.6557 L22: 0.7197 REMARK 3 L33: 1.7631 L12: 0.8547 REMARK 3 L13: -2.0680 L23: 0.6410 REMARK 3 S TENSOR REMARK 3 S11: 0.0077 S12: 0.3741 S13: -0.0117 REMARK 3 S21: -0.1465 S22: -0.0274 S23: 0.3759 REMARK 3 S31: 0.0700 S32: 0.0418 S33: -0.0293 REMARK 3 TLS GROUP : 7 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 574 THROUGH 583 ) REMARK 3 ORIGIN FOR THE GROUP (A): 31.0923 38.5425 24.4438 REMARK 3 T TENSOR REMARK 3 T11: 0.4416 T22: 0.4016 REMARK 3 T33: 0.7014 T12: 0.0223 REMARK 3 T13: -0.0748 T23: 0.0061 REMARK 3 L TENSOR REMARK 3 L11: 6.2006 L22: 5.0837 REMARK 3 L33: 6.5144 L12: -3.1204 REMARK 3 L13: -5.5345 L23: 5.1541 REMARK 3 S TENSOR REMARK 3 S11: -0.5048 S12: -1.2796 S13: -1.0846 REMARK 3 S21: 1.4199 S22: 0.4116 S23: -0.8843 REMARK 3 S31: 1.0335 S32: 0.8363 S33: 0.2301 REMARK 3 TLS GROUP : 8 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 584 THROUGH 596 ) REMARK 3 ORIGIN FOR THE GROUP (A): 12.2746 38.8653 29.9899 REMARK 3 T TENSOR REMARK 3 T11: 0.4063 T22: 0.1769 REMARK 3 T33: 0.5322 T12: 0.0602 REMARK 3 T13: 0.0335 T23: 0.0301 REMARK 3 L TENSOR REMARK 3 L11: 3.9535 L22: 3.9985 REMARK 3 L33: 3.3327 L12: -3.8102 REMARK 3 L13: 0.5477 L23: 0.5416 REMARK 3 S TENSOR REMARK 3 S11: -0.1462 S12: -0.7279 S13: -0.8330 REMARK 3 S21: 0.5891 S22: 0.0881 S23: 0.3924 REMARK 3 S31: 0.3563 S32: -0.0884 S33: -0.1349 REMARK 3 TLS GROUP : 9 REMARK 3 SELECTION: CHAIN 'D' AND (RESID 1 THROUGH 8 ) REMARK 3 ORIGIN FOR THE GROUP (A): 19.7199 29.6160 10.6758 REMARK 3 T TENSOR REMARK 3 T11: 0.7033 T22: 0.4702 REMARK 3 T33: 0.4919 T12: 0.1370 REMARK 3 T13: 0.1831 T23: -0.0003 REMARK 3 L TENSOR REMARK 3 L11: 2.8524 L22: 4.3756 REMARK 3 L33: 7.3931 L12: -0.6478 REMARK 3 L13: 3.0956 L23: -4.8063 REMARK 3 S TENSOR REMARK 3 S11: 0.4215 S12: 0.7704 S13: 0.2370 REMARK 3 S21: -0.2978 S22: 0.1906 S23: 0.7560 REMARK 3 S31: -0.5467 S32: 0.3205 S33: -0.4908 REMARK 3 TLS GROUP : 10 REMARK 3 SELECTION: CHAIN 'D' AND (RESID 9 THROUGH 18 ) REMARK 3 ORIGIN FOR THE GROUP (A): 11.4267 22.1114 39.3357 REMARK 3 T TENSOR REMARK 3 T11: 1.3790 T22: 0.8066 REMARK 3 T33: 0.9347 T12: 0.1695 REMARK 3 T13: 0.4324 T23: 0.0865 REMARK 3 L TENSOR REMARK 3 L11: 6.3470 L22: 0.9323 REMARK 3 L33: 5.5691 L12: 1.5558 REMARK 3 L13: 1.1935 L23: -0.8937 REMARK 3 S TENSOR REMARK 3 S11: 0.1177 S12: -1.7596 S13: 0.3935 REMARK 3 S21: 2.4678 S22: 0.3806 S23: 0.8939 REMARK 3 S31: 0.7411 S32: -1.0670 S33: -0.4108 REMARK 3 TLS GROUP : 11 REMARK 3 SELECTION: CHAIN 'E' AND (RESID 19 THROUGH 26 ) REMARK 3 ORIGIN FOR THE GROUP (A): 9.4049 19.9568 43.7955 REMARK 3 T TENSOR REMARK 3 T11: 1.7060 T22: 1.1368 REMARK 3 T33: 1.0664 T12: -0.0194 REMARK 3 T13: 0.5120 T23: 0.3701 REMARK 3 L TENSOR REMARK 3 L11: 5.4242 L22: 1.0079 REMARK 3 L33: 0.8049 L12: -1.3399 REMARK 3 L13: -1.8508 L23: 0.7959 REMARK 3 S TENSOR REMARK 3 S11: -0.4082 S12: -2.5111 S13: -0.7050 REMARK 3 S21: 1.9804 S22: 0.0378 S23: 0.2373 REMARK 3 S31: 1.9877 S32: 0.3653 S33: 0.9646 REMARK 3 TLS GROUP : 12 REMARK 3 SELECTION: CHAIN 'E' AND (RESID 27 THROUGH 36 ) REMARK 3 ORIGIN FOR THE GROUP (A): 20.3464 25.7129 13.8652 REMARK 3 T TENSOR REMARK 3 T11: 0.9167 T22: 0.5660 REMARK 3 T33: 0.4856 T12: -0.2195 REMARK 3 T13: 0.0959 T23: -0.0639 REMARK 3 L TENSOR REMARK 3 L11: 8.1278 L22: 6.0268 REMARK 3 L33: 2.6601 L12: -3.4594 REMARK 3 L13: -1.3332 L23: 2.1146 REMARK 3 S TENSOR REMARK 3 S11: -0.2648 S12: 1.8078 S13: -0.3831 REMARK 3 S21: -1.5727 S22: 0.1095 S23: -0.0165 REMARK 3 S31: 0.2552 S32: -0.2965 S33: 0.2069 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 5VMV COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 03-MAY-17. REMARK 100 THE DEPOSITION ID IS D_1000226559. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 05-MAR-14 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 8.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRL REMARK 200 BEAMLINE : BL11-1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.9795 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 17383 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.313 REMARK 200 RESOLUTION RANGE LOW (A) : 45.443 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 90.8 REMARK 200 DATA REDUNDANCY : 6.000 REMARK 200 R MERGE (I) : 0.08636 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 13.1100 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.31 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.40 REMARK 200 COMPLETENESS FOR SHELL (%) : 51.2 REMARK 200 DATA REDUNDANCY IN SHELL : 3.60 REMARK 200 R MERGE FOR SHELL (I) : 0.27650 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 4.290 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX 1.9_1692 REMARK 200 STARTING MODEL: 4F6N REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 68.38 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.89 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1 M TRIS PH 8.5, 0.2 M AMMONIUM REMARK 280 ACETATE, 30 % (V/V) 2-PROPANOL, VAPOR DIFFUSION, SITTING DROP, REMARK 280 TEMPERATURE 277K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 2 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z REMARK 290 3555 -X,Y,-Z REMARK 290 4555 X,-Y,-Z REMARK 290 5555 X+1/2,Y+1/2,Z REMARK 290 6555 -X+1/2,-Y+1/2,Z REMARK 290 7555 -X+1/2,Y+1/2,-Z REMARK 290 8555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 22.10950 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 91.89600 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 22.10950 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 91.89600 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 22.10950 REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 91.89600 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 22.10950 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 91.89600 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, D, E REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 CL CL A 704 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 846 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 471 REMARK 465 ALA A 472 REMARK 465 ASN A 473 REMARK 465 LYS A 474 REMARK 465 ARG A 475 REMARK 465 MET A 476 REMARK 465 LYS A 477 REMARK 465 VAL A 478 REMARK 465 LYS A 479 REMARK 465 HIS A 480 REMARK 465 TYR A 597 REMARK 465 ALA A 598 REMARK 465 TYR A 599 REMARK 465 LEU A 600 REMARK 465 SER A 601 REMARK 465 ASP A 602 REMARK 465 ARG A 603 REMARK 465 SER A 604 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 SG CYS A 527 O HOH A 803 2.13 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DC D 3 O4' - C1' - N1 ANGL. DEV. = 1.9 DEGREES REMARK 500 DA E 30 O4' - C1' - N9 ANGL. DEV. = 1.9 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 CYS A 555 -12.04 -140.61 REMARK 500 SER A 574 52.20 32.40 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 701 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 496 SG REMARK 620 2 CYS A 499 SG 120.2 REMARK 620 3 HIS A 512 NE2 109.0 98.6 REMARK 620 4 HIS A 516 NE2 111.8 111.0 104.2 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 702 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 524 SG REMARK 620 2 CYS A 527 SG 121.9 REMARK 620 3 HIS A 540 NE2 111.4 107.9 REMARK 620 4 HIS A 544 NE2 108.3 110.0 93.7 REMARK 620 5 HOH A 803 O 177.5 56.8 71.1 70.9 REMARK 620 N 1 2 3 4 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 703 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 552 SG REMARK 620 2 CYS A 555 SG 112.9 REMARK 620 3 HIS A 568 NE2 114.2 110.3 REMARK 620 4 HIS A 573 NE2 100.6 113.7 104.5 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 701 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 702 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 703 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue CL A 704 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5VMW RELATED DB: PDB REMARK 900 RELATED ID: 5VMU RELATED DB: PDB REMARK 900 RELATED ID: 5VMX RELATED DB: PDB REMARK 900 RELATED ID: 5VMY RELATED DB: PDB REMARK 900 RELATED ID: 5VMZ RELATED DB: PDB DBREF 5VMV A 471 604 UNP Q86T24 KAISO_HUMAN 471 604 DBREF 5VMV D 1 18 PDB 5VMV 5VMV 1 18 DBREF 5VMV E 19 36 PDB 5VMV 5VMV 19 36 SEQRES 1 A 134 MET ALA ASN LYS ARG MET LYS VAL LYS HIS ASP ASP HIS SEQRES 2 A 134 TYR GLU LEU ILE VAL ASP GLY ARG VAL TYR TYR ILE CYS SEQRES 3 A 134 ILE VAL CYS LYS ARG SER TYR VAL CYS LEU THR SER LEU SEQRES 4 A 134 ARG ARG HIS PHE ASN ILE HIS SER TRP GLU LYS LYS TYR SEQRES 5 A 134 PRO CYS ARG TYR CYS GLU LYS VAL PHE PRO LEU ALA GLU SEQRES 6 A 134 TYR ARG THR LYS HIS GLU ILE HIS HIS THR GLY GLU ARG SEQRES 7 A 134 ARG TYR GLN CYS LEU ALA CYS GLY LYS SER PHE ILE ASN SEQRES 8 A 134 TYR GLN PHE MET SER SER HIS ILE LYS SER VAL HIS SER SEQRES 9 A 134 GLN ASP PRO SER GLY ASP SER LYS LEU TYR ARG LEU HIS SEQRES 10 A 134 PRO CYS ARG SER LEU GLN ILE ARG GLN TYR ALA TYR LEU SEQRES 11 A 134 SER ASP ARG SER SEQRES 1 D 18 DT DG DC DT DT DC DT 5CM DG 5CM DG DA DG SEQRES 2 D 18 DA DA DG DC DA SEQRES 1 E 18 DT DG DC DT DT DC DT 5CM DG 5CM DG DA DG SEQRES 2 E 18 DA DA DG DC DA HET 5CM D 8 20 HET 5CM D 10 20 HET 5CM E 26 20 HET 5CM E 28 20 HET ZN A 701 1 HET ZN A 702 1 HET ZN A 703 1 HET CL A 704 1 HETNAM 5CM 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE HETNAM ZN ZINC ION HETNAM CL CHLORIDE ION FORMUL 2 5CM 4(C10 H16 N3 O7 P) FORMUL 4 ZN 3(ZN 2+) FORMUL 7 CL CL 1- FORMUL 8 HOH *76(H2 O) HELIX 1 AA1 CYS A 505 TRP A 518 1 14 HELIX 2 AA2 LEU A 533 GLY A 546 1 14 HELIX 3 AA3 ASN A 561 SER A 574 1 14 SHEET 1 AA1 3 HIS A 483 VAL A 488 0 SHEET 2 AA1 3 ARG A 491 CYS A 496 -1 O ILE A 495 N TYR A 484 SHEET 3 AA1 3 SER A 502 TYR A 503 -1 O TYR A 503 N TYR A 494 SHEET 1 AA2 2 TYR A 522 PRO A 523 0 SHEET 2 AA2 2 VAL A 530 PHE A 531 -1 O PHE A 531 N TYR A 522 SHEET 1 AA3 3 SER A 558 PHE A 559 0 SHEET 2 AA3 3 TYR A 550 CYS A 552 -1 N TYR A 550 O PHE A 559 SHEET 3 AA3 3 TYR A 584 LEU A 586 -1 O ARG A 585 N GLN A 551 LINK SG CYS A 496 ZN ZN A 701 1555 1555 2.28 LINK SG CYS A 499 ZN ZN A 701 1555 1555 2.19 LINK NE2 HIS A 512 ZN ZN A 701 1555 1555 1.96 LINK NE2 HIS A 516 ZN ZN A 701 1555 1555 1.95 LINK SG CYS A 524 ZN ZN A 702 1555 1555 2.21 LINK SG CYS A 527 ZN ZN A 702 1555 1555 2.31 LINK NE2 HIS A 540 ZN ZN A 702 1555 1555 2.03 LINK NE2 HIS A 544 ZN ZN A 702 1555 1555 2.12 LINK SG CYS A 552 ZN ZN A 703 1555 1555 2.27 LINK SG CYS A 555 ZN ZN A 703 1555 1555 2.31 LINK NE2 HIS A 568 ZN ZN A 703 1555 1555 1.93 LINK NE2 HIS A 573 ZN ZN A 703 1555 1555 2.02 LINK O3' DT D 7 P 5CM D 8 1555 1555 1.60 LINK O3' 5CM D 8 P DG D 9 1555 1555 1.60 LINK O3' DG D 9 P 5CM D 10 1555 1555 1.61 LINK O3' 5CM D 10 P DG D 11 1555 1555 1.61 LINK O3' DT E 25 P 5CM E 26 1555 1555 1.60 LINK O3' 5CM E 26 P DG E 27 1555 1555 1.60 LINK O3' DG E 27 P 5CM E 28 1555 1555 1.61 LINK O3' 5CM E 28 P DG E 29 1555 1555 1.60 LINK ZN ZN A 702 O HOH A 803 1555 1555 2.17 SITE 1 AC1 4 CYS A 496 CYS A 499 HIS A 512 HIS A 516 SITE 1 AC2 5 CYS A 524 CYS A 527 HIS A 540 HIS A 544 SITE 2 AC2 5 HOH A 803 SITE 1 AC3 4 CYS A 552 CYS A 555 HIS A 568 HIS A 573 SITE 1 AC4 1 ARG A 548 CRYST1 44.219 183.792 104.566 90.00 90.00 90.00 C 2 2 2 16 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.022615 0.000000 0.000000 0.00000 SCALE2 0.000000 0.005441 0.000000 0.00000 SCALE3 0.000000 0.000000 0.009563 0.00000 ATOM 1 N ASP A 481 7.393 0.931 27.015 1.00 94.47 N ANISOU 1 N ASP A 481 11958 6451 17485 -484 483 -1088 N ATOM 2 CA ASP A 481 8.190 2.091 27.398 1.00 98.14 C ANISOU 2 CA ASP A 481 12573 7071 17643 -390 463 -1043 C ATOM 3 C ASP A 481 8.250 3.138 26.300 1.00 97.13 C ANISOU 3 C ASP A 481 12413 7130 17361 -360 257 -1198 C ATOM 4 O ASP A 481 7.625 2.985 25.253 1.00103.46 O ANISOU 4 O ASP A 481 13087 7935 18286 -398 117 -1340 O ATOM 5 CB ASP A 481 9.610 1.667 27.761 1.00100.78 C ANISOU 5 CB ASP A 481 13151 7409 17732 -298 457 -953 C ATOM 6 CG ASP A 481 9.725 1.188 29.186 1.00100.36 C ANISOU 6 CG ASP A 481 13220 7203 17709 -267 672 -765 C ATOM 7 OD1 ASP A 481 9.865 2.054 30.083 1.00101.33 O ANISOU 7 OD1 ASP A 481 13435 7357 17708 -208 750 -678 O ATOM 8 OD2 ASP A 481 9.681 -0.045 29.402 1.00 88.74 O ANISOU 8 OD2 ASP A 481 11782 5569 16368 -289 762 -704 O ATOM 9 N ASP A 482 9.007 4.206 26.549 1.00 86.79 N ANISOU 9 N ASP A 482 11236 5961 15781 -283 236 -1171 N ATOM 10 CA ASP A 482 9.299 5.192 25.513 1.00 77.53 C ANISOU 10 CA ASP A 482 10092 4961 14406 -236 71 -1299 C ATOM 11 C ASP A 482 10.802 5.232 25.225 1.00 74.59 C ANISOU 11 C ASP A 482 9910 4674 13757 -153 13 -1287 C ATOM 12 O ASP A 482 11.238 5.813 24.233 1.00 78.18 O ANISOU 12 O ASP A 482 10425 5247 14035 -108 -94 -1381 O ATOM 13 CB ASP A 482 8.772 6.581 25.913 1.00 69.76 C ANISOU 13 CB ASP A 482 9069 4065 13372 -225 107 -1303 C ATOM 14 CG ASP A 482 9.386 7.094 27.200 1.00 72.60 C ANISOU 14 CG ASP A 482 9565 4426 13593 -183 238 -1162 C ATOM 15 OD1 ASP A 482 9.939 6.278 27.970 1.00 84.80 O ANISOU 15 OD1 ASP A 482 11201 5867 15150 -168 323 -1047 O ATOM 16 OD2 ASP A 482 9.295 8.309 27.455 1.00 70.10 O ANISOU 16 OD2 ASP A 482 9284 4200 13153 -154 248 -1168 O ATOM 17 N HIS A 483 11.596 4.601 26.080 1.00 64.29 N ANISOU 17 N HIS A 483 8703 3294 12431 -124 95 -1168 N ATOM 18 CA HIS A 483 13.035 4.544 25.848 1.00 71.88 C ANISOU 18 CA HIS A 483 9799 4313 13200 -42 43 -1160 C ATOM 19 C HIS A 483 13.702 3.232 26.305 1.00 75.64 C ANISOU 19 C HIS A 483 10352 4650 13739 -11 89 -1071 C ATOM 20 O HIS A 483 13.055 2.367 26.886 1.00 66.26 O ANISOU 20 O HIS A 483 9139 3314 12720 -56 179 -1002 O ATOM 21 CB HIS A 483 13.708 5.701 26.554 1.00 61.69 C ANISOU 21 CB HIS A 483 8578 3116 11748 11 57 -1119 C ATOM 22 CG HIS A 483 13.853 5.500 28.024 1.00 62.54 C ANISOU 22 CG HIS A 483 8760 3110 11891 41 155 -980 C ATOM 23 ND1 HIS A 483 12.771 5.447 28.877 1.00 63.74 N ANISOU 23 ND1 HIS A 483 8885 3160 12172 -2 278 -901 N ATOM 24 CD2 HIS A 483 14.951 5.349 28.802 1.00 62.66 C ANISOU 24 CD2 HIS A 483 8895 3079 11834 127 151 -903 C ATOM 25 CE1 HIS A 483 13.197 5.273 30.114 1.00 64.90 C ANISOU 25 CE1 HIS A 483 9177 3198 12283 66 357 -771 C ATOM 26 NE2 HIS A 483 14.517 5.210 30.097 1.00 63.91 N ANISOU 26 NE2 HIS A 483 9143 3102 12036 150 260 -776 N ATOM 27 N TYR A 484 15.000 3.109 26.029 1.00 63.81 N ANISOU 27 N TYR A 484 8941 3189 12115 70 41 -1073 N ATOM 28 CA TYR A 484 15.831 2.116 26.699 1.00 64.91 C ANISOU 28 CA TYR A 484 9171 3205 12287 137 80 -975 C ATOM 29 C TYR A 484 17.177 2.743 27.074 1.00 72.92 C ANISOU 29 C TYR A 484 10237 4286 13182 238 38 -955 C ATOM 30 O TYR A 484 17.637 3.678 26.420 1.00 71.96 O ANISOU 30 O TYR A 484 10078 4303 12960 247 -16 -1036 O ATOM 31 CB TYR A 484 16.029 0.875 25.821 1.00 65.99 C ANISOU 31 CB TYR A 484 9335 3260 12477 139 57 -1011 C ATOM 32 CG TYR A 484 16.690 1.119 24.478 1.00 65.00 C ANISOU 32 CG TYR A 484 9227 3235 12235 177 -23 -1119 C ATOM 33 CD1 TYR A 484 18.071 1.170 24.366 1.00 64.53 C ANISOU 33 CD1 TYR A 484 9216 3206 12097 278 -34 -1106 C ATOM 34 CD2 TYR A 484 15.938 1.264 23.318 1.00 64.91 C ANISOU 34 CD2 TYR A 484 9193 3263 12206 125 -80 -1232 C ATOM 35 CE1 TYR A 484 18.695 1.376 23.143 1.00 63.95 C ANISOU 35 CE1 TYR A 484 9180 3196 11923 322 -64 -1190 C ATOM 36 CE2 TYR A 484 16.555 1.469 22.083 1.00 64.31 C ANISOU 36 CE2 TYR A 484 9199 3246 11991 183 -126 -1316 C ATOM 37 CZ TYR A 484 17.939 1.516 22.006 1.00 63.83 C ANISOU 37 CZ TYR A 484 9198 3209 11847 279 -99 -1287 C ATOM 38 OH TYR A 484 18.590 1.733 20.807 1.00 63.51 O ANISOU 38 OH TYR A 484 9256 3202 11674 347 -104 -1355 O ATOM 39 N GLU A 485 17.811 2.236 28.126 1.00 67.87 N ANISOU 39 N GLU A 485 9687 3532 12568 323 61 -849 N ATOM 40 CA GLU A 485 19.105 2.771 28.549 1.00 64.57 C ANISOU 40 CA GLU A 485 9289 3151 12094 429 -8 -841 C ATOM 41 C GLU A 485 20.272 2.110 27.807 1.00 68.70 C ANISOU 41 C GLU A 485 9785 3669 12649 503 -52 -876 C ATOM 42 O GLU A 485 20.190 0.962 27.373 1.00 78.14 O ANISOU 42 O GLU A 485 11020 4776 13895 508 -19 -861 O ATOM 43 CB GLU A 485 19.293 2.599 30.058 1.00 69.43 C ANISOU 43 CB GLU A 485 10041 3625 12712 527 7 -715 C ATOM 44 CG GLU A 485 18.280 3.334 30.921 1.00 70.63 C ANISOU 44 CG GLU A 485 10257 3758 12819 484 73 -662 C ATOM 45 CD GLU A 485 18.448 3.024 32.401 1.00 81.74 C ANISOU 45 CD GLU A 485 11879 4984 14195 617 104 -519 C ATOM 46 OE1 GLU A 485 17.850 3.740 33.232 1.00 89.02 O ANISOU 46 OE1 GLU A 485 12899 5873 15051 623 155 -463 O ATOM 47 OE2 GLU A 485 19.169 2.053 32.733 1.00 84.92 O ANISOU 47 OE2 GLU A 485 12379 5262 14623 735 81 -454 O ATOM 48 N LEU A 486 21.363 2.853 27.678 1.00 71.80 N ANISOU 48 N LEU A 486 10106 4144 13031 560 -120 -925 N ATOM 49 CA LEU A 486 22.559 2.386 26.998 1.00 64.76 C ANISOU 49 CA LEU A 486 9159 3244 12201 640 -145 -959 C ATOM 50 C LEU A 486 23.750 2.807 27.828 1.00 66.21 C ANISOU 50 C LEU A 486 9279 3407 12470 749 -241 -944 C ATOM 51 O LEU A 486 24.019 3.992 27.928 1.00 74.91 O ANISOU 51 O LEU A 486 10299 4603 13560 722 -291 -1003 O ATOM 52 CB LEU A 486 22.652 2.977 25.587 1.00 63.52 C ANISOU 52 CB LEU A 486 8943 3212 11980 586 -118 -1067 C ATOM 53 CG LEU A 486 23.256 2.116 24.472 1.00 80.04 C ANISOU 53 CG LEU A 486 11060 5260 14092 640 -78 -1095 C ATOM 54 CD1 LEU A 486 22.940 2.685 23.093 1.00 63.35 C ANISOU 54 CD1 LEU A 486 8983 3237 11851 592 -39 -1188 C ATOM 55 CD2 LEU A 486 24.752 1.964 24.653 1.00 86.28 C ANISOU 55 CD2 LEU A 486 11757 6009 15016 759 -99 -1084 C ATOM 56 N ILE A 487 24.462 1.862 28.438 1.00 73.11 N ANISOU 56 N ILE A 487 10191 4149 13438 881 -285 -872 N ATOM 57 CA ILE A 487 25.575 2.252 29.295 1.00 68.27 C ANISOU 57 CA ILE A 487 9506 3502 12931 1009 -434 -870 C ATOM 58 C ILE A 487 26.925 1.919 28.690 1.00 72.87 C ANISOU 58 C ILE A 487 9928 4077 13682 1103 -478 -917 C ATOM 59 O ILE A 487 27.252 0.748 28.469 1.00 70.48 O ANISOU 59 O ILE A 487 9672 3682 13425 1190 -438 -866 O ATOM 60 CB ILE A 487 25.500 1.601 30.671 1.00 70.06 C ANISOU 60 CB ILE A 487 9909 3570 13141 1146 -499 -748 C ATOM 61 CG1 ILE A 487 24.073 1.618 31.202 1.00 69.58 C ANISOU 61 CG1 ILE A 487 10034 3469 12935 1061 -383 -673 C ATOM 62 CG2 ILE A 487 26.421 2.315 31.629 1.00 71.13 C ANISOU 62 CG2 ILE A 487 9992 3687 13346 1275 -721 -768 C ATOM 63 CD1 ILE A 487 23.968 1.087 32.601 1.00 71.57 C ANISOU 63 CD1 ILE A 487 10519 3540 13135 1215 -407 -536 C ATOM 64 N VAL A 488 27.711 2.960 28.426 1.00 68.91 N ANISOU 64 N VAL A 488 9236 3660 13287 1087 -544 -1014 N ATOM 65 CA VAL A 488 29.055 2.769 27.896 1.00 74.84 C ANISOU 65 CA VAL A 488 9792 4389 14254 1176 -569 -1064 C ATOM 66 C VAL A 488 30.061 3.443 28.807 1.00 78.82 C ANISOU 66 C VAL A 488 10123 4866 14959 1269 -797 -1114 C ATOM 67 O VAL A 488 29.931 4.635 29.093 1.00 83.31 O ANISOU 67 O VAL A 488 10638 5502 15513 1188 -867 -1184 O ATOM 68 CB VAL A 488 29.216 3.339 26.476 1.00 71.58 C ANISOU 68 CB VAL A 488 9284 4075 13840 1075 -405 -1151 C ATOM 69 CG1 VAL A 488 30.546 2.875 25.889 1.00 70.77 C ANISOU 69 CG1 VAL A 488 9007 3910 13970 1183 -369 -1175 C ATOM 70 CG2 VAL A 488 28.065 2.916 25.585 1.00 67.58 C ANISOU 70 CG2 VAL A 488 8971 3607 13100 981 -251 -1130 C ATOM 71 N ASP A 489 31.065 2.689 29.248 1.00 73.99 N ANISOU 71 N ASP A 489 9426 4152 14535 1448 -932 -1088 N ATOM 72 CA ASP A 489 32.062 3.186 30.200 1.00 90.85 C ANISOU 72 CA ASP A 489 11394 6242 16882 1576 -1229 -1147 C ATOM 73 C ASP A 489 31.403 3.677 31.488 1.00 91.63 C ANISOU 73 C ASP A 489 11695 6320 16800 1603 -1422 -1116 C ATOM 74 O ASP A 489 31.909 4.596 32.131 1.00 98.33 O ANISOU 74 O ASP A 489 12439 7171 17751 1634 -1668 -1207 O ATOM 75 CB ASP A 489 32.891 4.335 29.605 1.00 94.01 C ANISOU 75 CB ASP A 489 11480 6705 17533 1487 -1236 -1295 C ATOM 76 CG ASP A 489 33.228 4.130 28.144 1.00 92.17 C ANISOU 76 CG ASP A 489 11126 6507 17389 1416 -946 -1317 C ATOM 77 OD1 ASP A 489 33.580 2.993 27.757 1.00 80.24 O ANISOU 77 OD1 ASP A 489 9633 4934 15921 1520 -862 -1251 O ATOM 78 OD2 ASP A 489 33.128 5.119 27.384 1.00 94.53 O ANISOU 78 OD2 ASP A 489 11347 6887 17684 1268 -795 -1394 O ATOM 79 N GLY A 490 30.267 3.089 31.851 1.00 82.40 N ANISOU 79 N GLY A 490 10825 5116 15369 1591 -1304 -994 N ATOM 80 CA GLY A 490 29.524 3.542 33.014 1.00 78.41 C ANISOU 80 CA GLY A 490 10556 4573 14662 1617 -1415 -942 C ATOM 81 C GLY A 490 28.704 4.803 32.759 1.00 80.03 C ANISOU 81 C GLY A 490 10763 4893 14752 1414 -1318 -1007 C ATOM 82 O GLY A 490 27.849 5.167 33.567 1.00 78.15 O ANISOU 82 O GLY A 490 10748 4628 14317 1407 -1326 -950 O ATOM 83 N ARG A 491 28.966 5.479 31.642 1.00 82.36 N ANISOU 83 N ARG A 491 10832 5307 15153 1265 -1207 -1118 N ATOM 84 CA ARG A 491 28.147 6.622 31.231 1.00 89.27 C ANISOU 84 CA ARG A 491 11725 6306 15887 1079 -1080 -1172 C ATOM 85 C ARG A 491 26.757 6.122 30.796 1.00 85.28 C ANISOU 85 C ARG A 491 11404 5833 15165 980 -838 -1083 C ATOM 86 O ARG A 491 26.638 5.189 29.996 1.00 82.32 O ANISOU 86 O ARG A 491 11027 5452 14799 970 -699 -1050 O ATOM 87 CB ARG A 491 28.820 7.412 30.094 1.00 85.11 C ANISOU 87 CB ARG A 491 10949 5883 15508 973 -997 -1298 C ATOM 88 CG ARG A 491 30.150 8.068 30.464 1.00 95.51 C ANISOU 88 CG ARG A 491 12025 7160 17105 1034 -1222 -1414 C ATOM 89 CD ARG A 491 30.710 8.931 29.315 1.00111.26 C ANISOU 89 CD ARG A 491 13792 9236 19247 911 -1062 -1526 C ATOM 90 NE ARG A 491 32.002 9.548 29.641 1.00119.51 N ANISOU 90 NE ARG A 491 14555 10218 20635 949 -1260 -1653 N ATOM 91 CZ ARG A 491 32.722 10.298 28.804 1.00113.33 C ANISOU 91 CZ ARG A 491 13533 9458 20067 860 -1126 -1755 C ATOM 92 NH1 ARG A 491 33.882 10.804 29.200 1.00114.21 N ANISOU 92 NH1 ARG A 491 13357 9487 20552 892 -1325 -1880 N ATOM 93 NH2 ARG A 491 32.278 10.559 27.580 1.00106.28 N ANISOU 93 NH2 ARG A 491 12700 8659 19024 751 -801 -1737 N ATOM 94 N VAL A 492 25.706 6.735 31.327 1.00 78.73 N ANISOU 94 N VAL A 492 10732 5027 14156 912 -799 -1052 N ATOM 95 CA VAL A 492 24.346 6.315 31.012 1.00 67.16 C ANISOU 95 CA VAL A 492 9404 3577 12538 820 -599 -981 C ATOM 96 C VAL A 492 23.676 7.204 29.984 1.00 63.13 C ANISOU 96 C VAL A 492 8828 3228 11931 662 -478 -1060 C ATOM 97 O VAL A 492 23.491 8.382 30.219 1.00 63.39 O ANISOU 97 O VAL A 492 8863 3331 11891 610 -507 -1109 O ATOM 98 CB VAL A 492 23.469 6.302 32.265 1.00 65.90 C ANISOU 98 CB VAL A 492 9475 3310 12255 865 -592 -873 C ATOM 99 CG1 VAL A 492 22.010 6.079 31.890 1.00 64.84 C ANISOU 99 CG1 VAL A 492 9419 3198 12021 743 -387 -825 C ATOM 100 CG2 VAL A 492 23.959 5.238 33.222 1.00 74.39 C ANISOU 100 CG2 VAL A 492 10689 4205 13370 1051 -678 -765 C ATOM 101 N TYR A 493 23.302 6.637 28.848 1.00 62.45 N ANISOU 101 N TYR A 493 8713 3189 11825 603 -360 -1074 N ATOM 102 CA TYR A 493 22.490 7.354 27.890 1.00 60.74 C ANISOU 102 CA TYR A 493 8490 3105 11485 489 -269 -1136 C ATOM 103 C TYR A 493 21.075 6.803 27.892 1.00 62.86 C ANISOU 103 C TYR A 493 8855 3346 11684 431 -191 -1082 C ATOM 104 O TYR A 493 20.844 5.654 28.258 1.00 61.74 O ANISOU 104 O TYR A 493 8772 3085 11602 464 -168 -1006 O ATOM 105 CB TYR A 493 23.093 7.264 26.502 1.00 60.40 C ANISOU 105 CB TYR A 493 8368 3123 11459 485 -218 -1209 C ATOM 106 CG TYR A 493 24.536 7.650 26.507 1.00 68.77 C ANISOU 106 CG TYR A 493 9292 4176 12662 543 -269 -1257 C ATOM 107 CD1 TYR A 493 24.918 8.983 26.546 1.00 60.53 C ANISOU 107 CD1 TYR A 493 8178 3208 11613 503 -289 -1329 C ATOM 108 CD2 TYR A 493 25.529 6.683 26.513 1.00 68.74 C ANISOU 108 CD2 TYR A 493 9216 4074 12827 640 -300 -1235 C ATOM 109 CE1 TYR A 493 26.239 9.334 26.572 1.00 66.87 C ANISOU 109 CE1 TYR A 493 8815 3984 12610 543 -340 -1387 C ATOM 110 CE2 TYR A 493 26.852 7.032 26.535 1.00 63.69 C ANISOU 110 CE2 TYR A 493 8404 3413 12381 696 -356 -1289 C ATOM 111 CZ TYR A 493 27.198 8.355 26.570 1.00 63.22 C ANISOU 111 CZ TYR A 493 8249 3422 12349 641 -378 -1369 C ATOM 112 OH TYR A 493 28.515 8.706 26.593 1.00 71.33 O ANISOU 112 OH TYR A 493 9066 4409 13628 683 -434 -1437 O ATOM 113 N TYR A 494 20.131 7.652 27.510 1.00 68.90 N ANISOU 113 N TYR A 494 9628 4209 12340 347 -151 -1125 N ATOM 114 CA TYR A 494 18.744 7.272 27.374 1.00 59.31 C ANISOU 114 CA TYR A 494 8447 2976 11114 282 -93 -1102 C ATOM 115 C TYR A 494 18.367 7.393 25.903 1.00 58.52 C ANISOU 115 C TYR A 494 8314 2968 10953 240 -86 -1196 C ATOM 116 O TYR A 494 18.515 8.446 25.302 1.00 65.86 O ANISOU 116 O TYR A 494 9242 4009 11774 231 -91 -1265 O ATOM 117 CB TYR A 494 17.866 8.152 28.257 1.00 58.95 C ANISOU 117 CB TYR A 494 8446 2939 11015 248 -65 -1069 C ATOM 118 CG TYR A 494 18.268 8.157 29.717 1.00 59.95 C ANISOU 118 CG TYR A 494 8675 2950 11156 320 -80 -976 C ATOM 119 CD1 TYR A 494 19.097 9.140 30.220 1.00 59.62 C ANISOU 119 CD1 TYR A 494 8654 2941 11056 363 -158 -1006 C ATOM 120 CD2 TYR A 494 17.818 7.174 30.591 1.00 72.49 C ANISOU 120 CD2 TYR A 494 10359 4372 12811 358 -18 -858 C ATOM 121 CE1 TYR A 494 19.466 9.159 31.550 1.00 60.85 C ANISOU 121 CE1 TYR A 494 8938 2970 11211 457 -210 -930 C ATOM 122 CE2 TYR A 494 18.183 7.181 31.931 1.00 65.16 C ANISOU 122 CE2 TYR A 494 9590 3309 11857 464 -34 -762 C ATOM 123 CZ TYR A 494 19.001 8.183 32.401 1.00 69.25 C ANISOU 123 CZ TYR A 494 10142 3865 12307 521 -146 -802 C ATOM 124 OH TYR A 494 19.374 8.214 33.723 1.00 74.12 O ANISOU 124 OH TYR A 494 10947 4332 12882 654 -204 -716 O ATOM 125 N ILE A 495 17.898 6.302 25.318 1.00 59.34 N ANISOU 125 N ILE A 495 8423 3005 11119 225 -76 -1198 N ATOM 126 CA ILE A 495 17.659 6.240 23.884 1.00 59.07 C ANISOU 126 CA ILE A 495 8409 3016 11019 217 -93 -1288 C ATOM 127 C ILE A 495 16.166 6.190 23.584 1.00 66.58 C ANISOU 127 C ILE A 495 9332 3958 12007 146 -108 -1327 C ATOM 128 O ILE A 495 15.432 5.361 24.134 1.00 66.48 O ANISOU 128 O ILE A 495 9275 3841 12142 101 -90 -1280 O ATOM 129 CB ILE A 495 18.347 4.995 23.218 1.00 62.55 C ANISOU 129 CB ILE A 495 8895 3367 11505 267 -92 -1288 C ATOM 130 CG1 ILE A 495 19.823 5.252 22.881 1.00 59.89 C ANISOU 130 CG1 ILE A 495 8568 3058 11130 349 -75 -1299 C ATOM 131 CG2 ILE A 495 17.689 4.704 21.900 1.00 66.48 C ANISOU 131 CG2 ILE A 495 9459 3855 11944 255 -118 -1373 C ATOM 132 CD1 ILE A 495 20.702 5.671 24.033 1.00 68.31 C ANISOU 132 CD1 ILE A 495 9558 4129 12269 381 -84 -1246 C ATOM 133 N CYS A 496 15.730 7.086 22.705 1.00 68.24 N ANISOU 133 N CYS A 496 9567 4260 12100 144 -138 -1414 N ATOM 134 CA CYS A 496 14.349 7.140 22.239 1.00 67.04 C ANISOU 134 CA CYS A 496 9369 4099 12003 96 -184 -1480 C ATOM 135 C CYS A 496 13.990 5.912 21.392 1.00 66.77 C ANISOU 135 C CYS A 496 9349 3958 12060 88 -237 -1530 C ATOM 136 O CYS A 496 14.620 5.689 20.363 1.00 60.63 O ANISOU 136 O CYS A 496 8699 3175 11164 148 -254 -1578 O ATOM 137 CB CYS A 496 14.146 8.419 21.427 1.00 57.95 C ANISOU 137 CB CYS A 496 8285 3060 10673 127 -210 -1563 C ATOM 138 SG CYS A 496 12.498 8.649 20.798 1.00 69.92 S ANISOU 138 SG CYS A 496 9732 4565 12269 97 -300 -1667 S ATOM 139 N ILE A 497 12.984 5.130 21.798 1.00 59.52 N ANISOU 139 N ILE A 497 8905 3243 10466 14 -175 -929 N ATOM 140 CA ILE A 497 12.683 3.885 21.069 1.00 65.23 C ANISOU 140 CA ILE A 497 9755 3810 11221 -21 -251 -978 C ATOM 141 C ILE A 497 12.237 4.139 19.631 1.00 66.97 C ANISOU 141 C ILE A 497 9910 4065 11472 -51 -293 -1061 C ATOM 142 O ILE A 497 12.430 3.284 18.765 1.00 59.56 O ANISOU 142 O ILE A 497 9068 3029 10532 -35 -349 -1162 O ATOM 143 CB ILE A 497 11.582 3.004 21.752 1.00 70.40 C ANISOU 143 CB ILE A 497 10495 4293 11961 -199 -284 -886 C ATOM 144 CG1 ILE A 497 10.300 3.794 22.006 1.00 74.12 C ANISOU 144 CG1 ILE A 497 10777 4829 12558 -349 -254 -832 C ATOM 145 CG2 ILE A 497 12.088 2.357 23.036 1.00 78.07 C ANISOU 145 CG2 ILE A 497 11628 5135 12898 -211 -277 -807 C ATOM 146 CD1 ILE A 497 9.174 2.919 22.509 1.00 75.06 C ANISOU 146 CD1 ILE A 497 10952 4777 12789 -578 -283 -771 C ATOM 147 N VAL A 498 11.644 5.304 19.377 1.00 58.80 N ANISOU 147 N VAL A 498 8717 3144 10481 -100 -279 -1030 N ATOM 148 CA VAL A 498 11.152 5.627 18.043 1.00 57.73 C ANISOU 148 CA VAL A 498 8539 3009 10386 -158 -348 -1088 C ATOM 149 C VAL A 498 12.277 6.020 17.076 1.00 64.64 C ANISOU 149 C VAL A 498 9466 3939 11157 -89 -343 -1207 C ATOM 150 O VAL A 498 12.394 5.430 16.004 1.00 69.42 O ANISOU 150 O VAL A 498 10157 4467 11751 -121 -400 -1328 O ATOM 151 CB VAL A 498 10.112 6.773 18.086 1.00 67.39 C ANISOU 151 CB VAL A 498 9571 4295 11739 -225 -370 -1019 C ATOM 152 CG1 VAL A 498 9.823 7.301 16.679 1.00 65.01 C ANISOU 152 CG1 VAL A 498 9258 3980 11464 -279 -478 -1065 C ATOM 153 CG2 VAL A 498 8.834 6.301 18.757 1.00 56.34 C ANISOU 153 CG2 VAL A 498 8073 2816 10516 -334 -386 -966 C ATOM 154 N CYS A 499 13.097 7.009 17.439 1.00 62.72 N ANISOU 154 N CYS A 499 9169 3813 10847 -21 -276 -1197 N ATOM 155 CA CYS A 499 14.119 7.513 16.514 1.00 53.86 C ANISOU 155 CA CYS A 499 8080 2732 9653 -8 -270 -1330 C ATOM 156 C CYS A 499 15.559 7.207 16.952 1.00 56.06 C ANISOU 156 C CYS A 499 8369 3057 9874 132 -199 -1440 C ATOM 157 O CYS A 499 16.521 7.696 16.351 1.00 53.98 O ANISOU 157 O CYS A 499 8091 2846 9575 137 -171 -1589 O ATOM 158 CB CYS A 499 13.931 9.028 16.298 1.00 63.96 C ANISOU 158 CB CYS A 499 9295 4078 10930 -82 -281 -1258 C ATOM 159 SG CYS A 499 14.303 10.110 17.701 1.00 52.04 S ANISOU 159 SG CYS A 499 7684 2693 9395 -2 -189 -1140 S ATOM 160 N LYS A 500 15.697 6.359 17.969 1.00 53.98 N ANISOU 160 N LYS A 500 8131 2756 9621 227 -184 -1389 N ATOM 161 CA LYS A 500 16.998 5.965 18.531 1.00 63.10 C ANISOU 161 CA LYS A 500 9282 3932 10761 382 -150 -1479 C ATOM 162 C LYS A 500 17.933 7.125 18.884 1.00 64.64 C ANISOU 162 C LYS A 500 9373 4270 10916 419 -79 -1496 C ATOM 163 O LYS A 500 19.148 6.965 18.843 1.00 73.99 O ANISOU 163 O LYS A 500 10504 5493 12117 533 -55 -1659 O ATOM 164 CB LYS A 500 17.763 5.008 17.588 1.00 73.88 C ANISOU 164 CB LYS A 500 10677 5231 12163 472 -184 -1731 C ATOM 165 CG LYS A 500 16.993 4.357 16.425 1.00 79.00 C ANISOU 165 CG LYS A 500 11411 5770 12834 377 -249 -1821 C ATOM 166 CD LYS A 500 15.918 3.362 16.858 1.00 81.24 C ANISOU 166 CD LYS A 500 11802 5902 13163 326 -312 -1677 C ATOM 167 CE LYS A 500 14.885 3.174 15.731 1.00 87.89 C ANISOU 167 CE LYS A 500 12697 6672 14026 171 -375 -1713 C ATOM 168 NZ LYS A 500 13.759 2.247 16.066 1.00 90.77 N ANISOU 168 NZ LYS A 500 13146 6888 14453 83 -437 -1593 N ATOM 169 N ARG A 501 17.394 8.281 19.251 1.00 61.49 N ANISOU 169 N ARG A 501 8929 3946 10489 330 -50 -1353 N ATOM 170 CA ARG A 501 18.265 9.400 19.622 1.00 61.56 C ANISOU 170 CA ARG A 501 8859 4066 10464 345 13 -1364 C ATOM 171 C ARG A 501 18.757 9.283 21.047 1.00 58.53 C ANISOU 171 C ARG A 501 8460 3712 10068 436 44 -1286 C ATOM 172 O ARG A 501 18.046 8.782 21.929 1.00 60.73 O ANISOU 172 O ARG A 501 8792 3933 10351 426 26 -1162 O ATOM 173 CB ARG A 501 17.559 10.733 19.451 1.00 60.80 C ANISOU 173 CB ARG A 501 8740 4009 10354 222 11 -1254 C ATOM 174 CG ARG A 501 17.820 11.402 18.137 1.00 61.10 C ANISOU 174 CG ARG A 501 8808 4025 10383 107 -15 -1361 C ATOM 175 CD ARG A 501 17.415 12.852 18.258 1.00 60.72 C ANISOU 175 CD ARG A 501 8761 3992 10320 11 -36 -1233 C ATOM 176 NE ARG A 501 17.019 13.420 16.981 1.00 66.64 N ANISOU 176 NE ARG A 501 9602 4651 11068 -157 -131 -1250 N ATOM 177 CZ ARG A 501 17.745 14.301 16.309 1.00 84.38 C ANISOU 177 CZ ARG A 501 11925 6871 13265 -315 -151 -1320 C ATOM 178 NH1 ARG A 501 18.908 14.716 16.800 1.00 84.59 N ANISOU 178 NH1 ARG A 501 11905 6970 13264 -302 -57 -1400 N ATOM 179 NH2 ARG A 501 17.302 14.773 15.151 1.00 93.38 N ANISOU 179 NH2 ARG A 501 13193 7904 14383 -524 -276 -1310 N ATOM 180 N SER A 502 19.970 9.780 21.256 1.00 50.60 N ANISOU 180 N SER A 502 7382 2784 9060 497 91 -1379 N ATOM 181 CA SER A 502 20.698 9.617 22.506 1.00 49.54 C ANISOU 181 CA SER A 502 7234 2660 8929 592 102 -1343 C ATOM 182 C SER A 502 20.544 10.822 23.434 1.00 47.85 C ANISOU 182 C SER A 502 6993 2518 8669 521 154 -1215 C ATOM 183 O SER A 502 20.674 11.970 23.005 1.00 47.07 O ANISOU 183 O SER A 502 6841 2491 8554 445 197 -1234 O ATOM 184 CB SER A 502 22.172 9.382 22.201 1.00 53.44 C ANISOU 184 CB SER A 502 7622 3196 9487 717 114 -1566 C ATOM 185 OG SER A 502 22.908 9.218 23.391 1.00 67.68 O ANISOU 185 OG SER A 502 9410 4989 11318 818 94 -1532 O ATOM 186 N TYR A 503 20.271 10.567 24.709 1.00 47.73 N ANISOU 186 N TYR A 503 7033 2459 8642 527 146 -1098 N ATOM 187 CA TYR A 503 20.065 11.657 25.652 1.00 46.60 C ANISOU 187 CA TYR A 503 6861 2374 8471 458 203 -1012 C ATOM 188 C TYR A 503 20.752 11.388 26.978 1.00 50.67 C ANISOU 188 C TYR A 503 7423 2840 8990 502 198 -980 C ATOM 189 O TYR A 503 20.593 10.325 27.570 1.00 53.34 O ANISOU 189 O TYR A 503 7872 3048 9348 523 139 -931 O ATOM 190 CB TYR A 503 18.564 11.911 25.866 1.00 49.45 C ANISOU 190 CB TYR A 503 7218 2718 8851 354 217 -917 C ATOM 191 CG TYR A 503 17.873 12.453 24.629 1.00 55.58 C ANISOU 191 CG TYR A 503 7947 3527 9643 307 201 -935 C ATOM 192 CD1 TYR A 503 17.281 11.587 23.716 1.00 46.71 C ANISOU 192 CD1 TYR A 503 6860 2339 8549 297 146 -954 C ATOM 193 CD2 TYR A 503 17.845 13.833 24.356 1.00 45.28 C ANISOU 193 CD2 TYR A 503 6592 2282 8330 263 221 -933 C ATOM 194 CE1 TYR A 503 16.662 12.052 22.584 1.00 46.76 C ANISOU 194 CE1 TYR A 503 6845 2343 8581 241 110 -968 C ATOM 195 CE2 TYR A 503 17.223 14.316 23.213 1.00 45.49 C ANISOU 195 CE2 TYR A 503 6618 2285 8381 210 168 -936 C ATOM 196 CZ TYR A 503 16.638 13.409 22.331 1.00 55.25 C ANISOU 196 CZ TYR A 503 7882 3460 9650 197 113 -953 C ATOM 197 OH TYR A 503 16.017 13.838 21.185 1.00 53.41 O ANISOU 197 OH TYR A 503 7665 3177 9451 128 41 -954 O ATOM 198 N VAL A 504 21.525 12.369 27.425 1.00 51.67 N ANISOU 198 N VAL A 504 7488 3041 9105 499 249 -1006 N ATOM 199 CA VAL A 504 22.223 12.304 28.699 1.00 55.50 C ANISOU 199 CA VAL A 504 8015 3469 9602 524 241 -979 C ATOM 200 C VAL A 504 21.229 12.400 29.835 1.00 56.81 C ANISOU 200 C VAL A 504 8263 3565 9757 407 272 -866 C ATOM 201 O VAL A 504 21.377 11.765 30.872 1.00 60.17 O ANISOU 201 O VAL A 504 8808 3852 10201 387 228 -807 O ATOM 202 CB VAL A 504 23.265 13.439 28.830 1.00 52.44 C ANISOU 202 CB VAL A 504 7530 3176 9219 523 300 -1053 C ATOM 203 CG1 VAL A 504 23.659 13.653 30.282 1.00 46.81 C ANISOU 203 CG1 VAL A 504 6877 2397 8513 497 306 -1001 C ATOM 204 CG2 VAL A 504 24.484 13.136 27.964 1.00 47.26 C ANISOU 204 CG2 VAL A 504 6758 2559 8637 635 277 -1224 C ATOM 205 N CYS A 505 20.198 13.200 29.627 1.00 57.41 N ANISOU 205 N CYS A 505 8267 3712 9833 318 346 -850 N ATOM 206 CA CYS A 505 19.199 13.406 30.656 1.00 53.34 C ANISOU 206 CA CYS A 505 7755 3143 9368 198 425 -806 C ATOM 207 C CYS A 505 17.842 12.879 30.197 1.00 54.15 C ANISOU 207 C CYS A 505 7826 3206 9543 140 429 -788 C ATOM 208 O CYS A 505 17.376 13.163 29.094 1.00 56.15 O ANISOU 208 O CYS A 505 8000 3529 9806 172 409 -814 O ATOM 209 CB CYS A 505 19.119 14.894 31.018 1.00 50.27 C ANISOU 209 CB CYS A 505 7268 2848 8986 157 534 -850 C ATOM 210 SG CYS A 505 20.741 15.622 31.448 1.00 63.52 S ANISOU 210 SG CYS A 505 8975 4568 10591 197 532 -883 S ATOM 211 N LEU A 506 17.220 12.083 31.050 1.00 56.35 N ANISOU 211 N LEU A 506 7350 3199 10861 609 226 -150 N ATOM 212 CA LEU A 506 15.903 11.549 30.764 1.00 64.25 C ANISOU 212 CA LEU A 506 8244 4015 12152 391 186 8 C ATOM 213 C LEU A 506 14.860 12.658 30.499 1.00 53.57 C ANISOU 213 C LEU A 506 6559 2776 11018 247 299 79 C ATOM 214 O LEU A 506 14.029 12.552 29.590 1.00 54.31 O ANISOU 214 O LEU A 506 6526 2826 11283 97 174 91 O ATOM 215 CB LEU A 506 15.465 10.657 31.925 1.00 56.87 C ANISOU 215 CB LEU A 506 7432 2866 11311 350 285 217 C ATOM 216 CG LEU A 506 14.232 9.806 31.717 1.00 59.64 C ANISOU 216 CG LEU A 506 7731 3007 11922 129 223 386 C ATOM 217 CD1 LEU A 506 14.498 8.729 30.674 1.00 68.98 C ANISOU 217 CD1 LEU A 506 9097 4063 13048 114 -59 269 C ATOM 218 CD2 LEU A 506 13.841 9.187 33.052 1.00 61.91 C ANISOU 218 CD2 LEU A 506 8119 3130 12275 94 390 612 C ATOM 219 N THR A 507 14.878 13.716 31.291 1.00 52.20 N ANISOU 219 N THR A 507 6251 2751 10834 300 530 126 N ATOM 220 CA THR A 507 13.880 14.776 31.064 1.00 57.80 C ANISOU 220 CA THR A 507 6648 3564 11749 177 645 194 C ATOM 221 C THR A 507 14.010 15.326 29.641 1.00 49.94 C ANISOU 221 C THR A 507 5564 2697 10713 153 456 9 C ATOM 222 O THR A 507 13.006 15.546 28.951 1.00 50.50 O ANISOU 222 O THR A 507 5446 2754 10988 10 392 51 O ATOM 223 CB THR A 507 13.999 15.911 32.086 1.00 54.64 C ANISOU 223 CB THR A 507 6138 3321 11302 262 926 251 C ATOM 224 OG1 THR A 507 15.311 16.491 32.027 1.00 47.78 O ANISOU 224 OG1 THR A 507 5385 2643 10127 441 897 58 O ATOM 225 CG2 THR A 507 13.733 15.364 33.486 1.00 52.10 C ANISOU 225 CG2 THR A 507 5909 2865 11021 279 1132 460 C ATOM 226 N SER A 508 15.248 15.480 29.191 1.00 48.17 N ANISOU 226 N SER A 508 5492 2598 10211 298 359 -190 N ATOM 227 CA SER A 508 15.510 15.801 27.795 1.00 46.95 C ANISOU 227 CA SER A 508 5318 2547 9973 286 173 -363 C ATOM 228 C SER A 508 14.802 14.834 26.856 1.00 52.73 C ANISOU 228 C SER A 508 6085 3101 10848 161 -43 -344 C ATOM 229 O SER A 508 14.142 15.248 25.890 1.00 56.69 O ANISOU 229 O SER A 508 6445 3640 11454 62 -144 -371 O ATOM 230 CB SER A 508 17.005 15.772 27.513 1.00 45.46 C ANISOU 230 CB SER A 508 5333 2492 9447 464 103 -554 C ATOM 231 OG SER A 508 17.668 16.894 28.078 1.00 44.29 O ANISOU 231 OG SER A 508 5127 2571 9130 566 260 -604 O ATOM 232 N LEU A 509 14.930 13.540 27.145 1.00 50.89 N ANISOU 232 N LEU A 509 6052 2674 10608 168 -122 -294 N ATOM 233 CA LEU A 509 14.314 12.545 26.288 1.00 55.08 C ANISOU 233 CA LEU A 509 6642 3034 11251 54 -335 -277 C ATOM 234 C LEU A 509 12.795 12.691 26.269 1.00 54.46 C ANISOU 234 C LEU A 509 6323 2884 11485 -140 -316 -109 C ATOM 235 O LEU A 509 12.201 12.602 25.212 1.00 55.08 O ANISOU 235 O LEU A 509 6340 2942 11647 -229 -489 -144 O ATOM 236 CB LEU A 509 14.702 11.107 26.703 1.00 54.98 C ANISOU 236 CB LEU A 509 6896 2815 11178 93 -411 -241 C ATOM 237 CG LEU A 509 13.949 10.073 25.862 1.00 57.36 C ANISOU 237 CG LEU A 509 7246 2933 11616 -42 -625 -208 C ATOM 238 CD1 LEU A 509 14.862 8.954 25.378 1.00 63.60 C ANISOU 238 CD1 LEU A 509 8326 3625 12212 64 -792 -331 C ATOM 239 CD2 LEU A 509 12.755 9.531 26.636 1.00 59.91 C ANISOU 239 CD2 LEU A 509 7479 3078 12206 -209 -558 26 C ATOM 240 N ARG A 510 12.164 12.878 27.421 1.00 55.25 N ANISOU 240 N ARG A 510 6296 2950 11748 -196 -105 76 N ATOM 241 CA ARG A 510 10.714 13.128 27.446 1.00 66.80 C ANISOU 241 CA ARG A 510 7497 4382 13504 -365 -57 238 C ATOM 242 C ARG A 510 10.344 14.318 26.548 1.00 59.26 C ANISOU 242 C ARG A 510 6326 3603 12586 -380 -98 145 C ATOM 243 O ARG A 510 9.531 14.187 25.595 1.00 60.20 O ANISOU 243 O ARG A 510 6356 3685 12831 -479 -276 140 O ATOM 244 CB ARG A 510 10.222 13.412 28.871 1.00 66.72 C ANISOU 244 CB ARG A 510 7365 4364 13620 -387 238 441 C ATOM 245 CG ARG A 510 10.707 12.454 29.949 1.00 68.66 C ANISOU 245 CG ARG A 510 7842 4460 13787 -341 329 539 C ATOM 246 CD ARG A 510 10.084 11.091 29.835 1.00 81.47 C ANISOU 246 CD ARG A 510 9568 5853 15533 -474 187 647 C ATOM 247 NE ARG A 510 10.262 10.335 31.071 1.00 85.93 N ANISOU 247 NE ARG A 510 10307 6277 16066 -455 333 798 N ATOM 248 CZ ARG A 510 10.084 9.024 31.177 1.00 76.55 C ANISOU 248 CZ ARG A 510 9306 4871 14910 -531 221 878 C ATOM 249 NH1 ARG A 510 9.719 8.318 30.115 1.00 78.12 N ANISOU 249 NH1 ARG A 510 9533 4970 15181 -629 -34 819 N ATOM 250 NH2 ARG A 510 10.273 8.420 32.345 1.00 78.15 N ANISOU 250 NH2 ARG A 510 9680 4951 15062 -504 365 1018 N ATOM 251 N ARG A 511 10.962 15.466 26.859 1.00 52.48 N ANISOU 251 N ARG A 511 5402 2932 11606 -273 58 71 N ATOM 252 CA ARG A 511 10.745 16.693 26.109 1.00 50.66 C ANISOU 252 CA ARG A 511 4992 2879 11378 -270 40 -22 C ATOM 253 C ARG A 511 10.791 16.373 24.619 1.00 50.76 C ANISOU 253 C ARG A 511 5093 2876 11319 -294 -246 -161 C ATOM 254 O ARG A 511 9.945 16.800 23.847 1.00 51.08 O ANISOU 254 O ARG A 511 4987 2943 11479 -364 -346 -159 O ATOM 255 CB ARG A 511 11.797 17.762 26.482 1.00 47.82 C ANISOU 255 CB ARG A 511 4644 2715 10809 -133 194 -135 C ATOM 256 CG ARG A 511 11.551 19.138 25.866 1.00 45.95 C ANISOU 256 CG ARG A 511 4217 2664 10577 -134 210 -213 C ATOM 257 CD ARG A 511 12.434 20.213 26.535 1.00 54.71 C ANISOU 257 CD ARG A 511 5315 3961 11512 -24 410 -278 C ATOM 258 NE ARG A 511 13.836 19.910 26.309 1.00 42.32 N ANISOU 258 NE ARG A 511 3989 2455 9636 91 331 -436 N ATOM 259 CZ ARG A 511 14.856 20.568 26.832 1.00 41.09 C ANISOU 259 CZ ARG A 511 3902 2466 9246 204 451 -511 C ATOM 260 NH1 ARG A 511 14.657 21.632 27.607 1.00 48.60 N ANISOU 260 NH1 ARG A 511 4711 3536 10219 207 657 -450 N ATOM 261 NH2 ARG A 511 16.091 20.160 26.566 1.00 40.62 N ANISOU 261 NH2 ARG A 511 4062 2466 8905 319 357 -646 N ATOM 262 N HIS A 512 11.757 15.561 24.224 1.00 51.32 N ANISOU 262 N HIS A 512 5420 2891 11187 -223 -378 -276 N ATOM 263 CA HIS A 512 11.842 15.144 22.830 1.00 51.11 C ANISOU 263 CA HIS A 512 5509 2836 11075 -233 -633 -400 C ATOM 264 C HIS A 512 10.694 14.229 22.356 1.00 53.95 C ANISOU 264 C HIS A 512 5840 3008 11649 -373 -807 -298 C ATOM 265 O HIS A 512 10.104 14.448 21.306 1.00 57.30 O ANISOU 265 O HIS A 512 6201 3446 12123 -423 -966 -338 O ATOM 266 CB HIS A 512 13.164 14.446 22.609 1.00 50.64 C ANISOU 266 CB HIS A 512 5731 2763 10748 -106 -705 -538 C ATOM 267 CG HIS A 512 13.173 13.570 21.405 1.00 54.53 C ANISOU 267 CG HIS A 512 6382 3153 11182 -123 -951 -619 C ATOM 268 ND1 HIS A 512 13.322 14.060 20.126 1.00 61.30 N ANISOU 268 ND1 HIS A 512 7255 4112 11924 -101 -1077 -749 N ATOM 269 CD2 HIS A 512 13.010 12.234 21.281 1.00 65.43 C ANISOU 269 CD2 HIS A 512 7918 4334 12609 -160 -1090 -582 C ATOM 270 CE1 HIS A 512 13.271 13.060 19.266 1.00 52.77 C ANISOU 270 CE1 HIS A 512 6332 2901 10818 -116 -1279 -791 C ATOM 271 NE2 HIS A 512 13.082 11.943 19.943 1.00 77.49 N ANISOU 271 NE2 HIS A 512 9544 5849 14048 -152 -1296 -695 N ATOM 272 N PHE A 513 10.383 13.199 23.129 1.00 60.97 N ANISOU 272 N PHE A 513 6787 3721 12656 -432 -780 -165 N ATOM 273 CA PHE A 513 9.471 12.133 22.706 1.00 59.03 C ANISOU 273 CA PHE A 513 6560 3282 12585 -559 -958 -79 C ATOM 274 C PHE A 513 8.062 12.679 22.535 1.00 70.05 C ANISOU 274 C PHE A 513 7677 4694 14247 -682 -959 35 C ATOM 275 O PHE A 513 7.208 12.094 21.822 1.00 73.43 O ANISOU 275 O PHE A 513 8077 5004 14819 -780 -1151 70 O ATOM 276 CB PHE A 513 9.489 10.999 23.723 1.00 61.05 C ANISOU 276 CB PHE A 513 6941 3356 12901 -596 -893 52 C ATOM 277 CG PHE A 513 8.850 9.725 23.237 1.00 64.09 C ANISOU 277 CG PHE A 513 7414 3527 13408 -707 -1100 108 C ATOM 278 CD1 PHE A 513 9.597 8.779 22.557 1.00 73.83 C ANISOU 278 CD1 PHE A 513 8914 4665 14471 -642 -1291 -15 C ATOM 279 CD2 PHE A 513 7.513 9.468 23.476 1.00 66.57 C ANISOU 279 CD2 PHE A 513 7543 3741 14009 -869 -1097 283 C ATOM 280 CE1 PHE A 513 9.021 7.593 22.118 1.00 74.65 C ANISOU 280 CE1 PHE A 513 9104 4568 14691 -739 -1485 34 C ATOM 281 CE2 PHE A 513 6.930 8.287 23.041 1.00 73.99 C ANISOU 281 CE2 PHE A 513 8562 4481 15069 -974 -1292 334 C ATOM 282 CZ PHE A 513 7.684 7.349 22.360 1.00 73.16 C ANISOU 282 CZ PHE A 513 8730 4275 14794 -911 -1491 209 C ATOM 283 N ASN A 514 7.809 13.820 23.173 1.00 65.61 N ANISOU 283 N ASN A 514 6904 4276 13748 -665 -748 89 N ATOM 284 CA ASN A 514 6.508 14.424 22.955 1.00 64.22 C ANISOU 284 CA ASN A 514 6465 4128 13805 -751 -750 180 C ATOM 285 C ASN A 514 6.295 14.759 21.476 1.00 61.71 C ANISOU 285 C ASN A 514 6154 3854 13441 -743 -993 47 C ATOM 286 O ASN A 514 5.158 14.827 21.022 1.00 60.89 O ANISOU 286 O ASN A 514 5898 3703 13535 -823 -1094 112 O ATOM 287 CB ASN A 514 6.320 15.666 23.809 1.00 62.75 C ANISOU 287 CB ASN A 514 6069 4102 13673 -707 -484 241 C ATOM 288 CG ASN A 514 4.869 16.109 23.860 1.00 67.96 C ANISOU 288 CG ASN A 514 6463 4758 14602 -788 -450 372 C ATOM 289 OD1 ASN A 514 3.968 15.290 24.048 1.00 67.79 O ANISOU 289 OD1 ASN A 514 6384 4588 14783 -902 -491 507 O ATOM 290 ND2 ASN A 514 4.635 17.402 23.679 1.00 71.27 N ANISOU 290 ND2 ASN A 514 6727 5334 15019 -726 -380 329 N ATOM 291 N ILE A 515 7.378 14.922 20.714 1.00 57.31 N ANISOU 291 N ILE A 515 5783 3375 12617 -643 -1088 -133 N ATOM 292 CA ILE A 515 7.228 15.218 19.293 1.00 57.06 C ANISOU 292 CA ILE A 515 5790 3380 12512 -629 -1306 -253 C ATOM 293 C ILE A 515 6.784 13.978 18.514 1.00 73.31 C ANISOU 293 C ILE A 515 7970 5246 14640 -700 -1559 -246 C ATOM 294 O ILE A 515 6.256 14.098 17.408 1.00 74.60 O ANISOU 294 O ILE A 515 8124 5393 14829 -718 -1753 -294 O ATOM 295 CB ILE A 515 8.528 15.805 18.678 1.00 63.57 C ANISOU 295 CB ILE A 515 6780 4358 13018 -501 -1310 -443 C ATOM 296 CG1 ILE A 515 8.200 16.633 17.435 1.00 76.74 C ANISOU 296 CG1 ILE A 515 8412 6115 14629 -485 -1446 -532 C ATOM 297 CG2 ILE A 515 9.522 14.740 18.320 1.00 55.97 C ANISOU 297 CG2 ILE A 515 6097 3310 11858 -445 -1417 -541 C ATOM 298 CD1 ILE A 515 9.404 16.952 16.575 1.00 77.55 C ANISOU 298 CD1 ILE A 515 8718 6333 14415 -377 -1490 -712 C ATOM 299 N HIS A 516 6.972 12.795 19.103 1.00 72.06 N ANISOU 299 N HIS A 516 7931 4933 14515 -738 -1559 -181 N ATOM 300 CA HIS A 516 6.474 11.550 18.518 1.00 72.76 C ANISOU 300 CA HIS A 516 8124 4821 14703 -816 -1788 -153 C ATOM 301 C HIS A 516 5.034 11.285 18.958 1.00 80.24 C ANISOU 301 C HIS A 516 8848 5653 15987 -963 -1787 34 C ATOM 302 O HIS A 516 4.189 10.887 18.153 1.00 78.62 O ANISOU 302 O HIS A 516 8603 5343 15925 -1033 -1999 51 O ATOM 303 CB HIS A 516 7.352 10.354 18.916 1.00 64.96 C ANISOU 303 CB HIS A 516 7388 3708 13588 -782 -1800 -173 C ATOM 304 CG HIS A 516 8.777 10.470 18.472 1.00 62.74 C ANISOU 304 CG HIS A 516 7331 3525 12981 -627 -1807 -357 C ATOM 305 ND1 HIS A 516 9.130 10.849 17.194 1.00 66.21 N ANISOU 305 ND1 HIS A 516 7852 4049 13255 -557 -1952 -511 N ATOM 306 CD2 HIS A 516 9.941 10.250 19.132 1.00 61.48 C ANISOU 306 CD2 HIS A 516 7335 3394 12632 -522 -1681 -410 C ATOM 307 CE1 HIS A 516 10.447 10.862 17.088 1.00 64.01 C ANISOU 307 CE1 HIS A 516 7762 3854 12703 -421 -1902 -647 C ATOM 308 NE2 HIS A 516 10.962 10.495 18.247 1.00 59.82 N ANISOU 308 NE2 HIS A 516 7282 3293 12155 -393 -1747 -594 N ATOM 309 N SER A 517 4.746 11.498 20.240 1.00 82.27 N ANISOU 309 N SER A 517 8959 5926 16373 -1005 -1544 178 N ATOM 310 CA SER A 517 3.409 11.147 20.725 1.00 70.00 C ANISOU 310 CA SER A 517 7201 4258 15138 -1146 -1518 367 C ATOM 311 C SER A 517 2.358 12.268 20.682 1.00 77.27 C ANISOU 311 C SER A 517 7827 5285 16247 -1167 -1449 427 C ATOM 312 O SER A 517 1.160 11.993 20.706 1.00 76.78 O ANISOU 312 O SER A 517 7596 5124 16454 -1275 -1497 551 O ATOM 313 CB SER A 517 3.506 10.619 22.153 1.00 70.92 C ANISOU 313 CB SER A 517 7326 4305 15315 -1193 -1288 519 C ATOM 314 OG SER A 517 3.888 11.629 23.061 1.00 68.64 O ANISOU 314 OG SER A 517 6939 4181 14961 -1117 -1012 543 O ATOM 315 N TRP A 518 2.801 13.521 20.630 1.00 75.69 N ANISOU 315 N TRP A 518 7569 5279 15909 -1061 -1338 339 N ATOM 316 CA TRP A 518 1.898 14.667 20.766 1.00 67.98 C ANISOU 316 CA TRP A 518 6329 4410 15089 -1056 -1232 397 C ATOM 317 C TRP A 518 0.936 14.520 21.935 1.00 69.50 C ANISOU 317 C TRP A 518 6317 4547 15544 -1144 -1027 605 C ATOM 318 O TRP A 518 -0.211 14.935 21.844 1.00 70.43 O ANISOU 318 O TRP A 518 6224 4656 15881 -1187 -1031 683 O ATOM 319 CB TRP A 518 1.103 14.888 19.476 1.00 68.23 C ANISOU 319 CB TRP A 518 6304 4410 15211 -1073 -1491 339 C ATOM 320 CG TRP A 518 1.846 15.696 18.485 1.00 71.12 C ANISOU 320 CG TRP A 518 6786 4909 15326 -961 -1591 156 C ATOM 321 CD1 TRP A 518 2.666 15.237 17.495 1.00 72.53 C ANISOU 321 CD1 TRP A 518 7207 5067 15284 -918 -1787 9 C ATOM 322 CD2 TRP A 518 1.867 17.122 18.395 1.00 69.12 C ANISOU 322 CD2 TRP A 518 6428 4833 15003 -874 -1488 100 C ATOM 323 NE1 TRP A 518 3.195 16.288 16.788 1.00 65.81 N ANISOU 323 NE1 TRP A 518 6403 4373 14228 -818 -1803 -128 N ATOM 324 CE2 TRP A 518 2.718 17.460 17.321 1.00 73.28 C ANISOU 324 CE2 TRP A 518 7139 5440 15264 -792 -1628 -76 C ATOM 325 CE3 TRP A 518 1.254 18.146 19.122 1.00 64.31 C ANISOU 325 CE3 TRP A 518 5599 4316 14520 -851 -1284 183 C ATOM 326 CZ2 TRP A 518 2.962 18.783 16.952 1.00 71.06 C ANISOU 326 CZ2 TRP A 518 6827 5327 14847 -703 -1576 -166 C ATOM 327 CZ3 TRP A 518 1.491 19.454 18.753 1.00 64.26 C ANISOU 327 CZ3 TRP A 518 5568 4468 14379 -752 -1244 86 C ATOM 328 CH2 TRP A 518 2.343 19.763 17.679 1.00 67.01 C ANISOU 328 CH2 TRP A 518 6100 4894 14468 -685 -1391 -85 C ATOM 329 N GLU A 519 1.400 13.914 23.023 1.00 74.64 N ANISOU 329 N GLU A 519 7042 5151 16165 -1166 -846 695 N ATOM 330 CA GLU A 519 0.532 13.641 24.161 1.00 78.94 C ANISOU 330 CA GLU A 519 7425 5632 16937 -1257 -636 904 C ATOM 331 C GLU A 519 0.136 14.952 24.821 1.00 76.19 C ANISOU 331 C GLU A 519 6862 5447 16638 -1187 -385 956 C ATOM 332 O GLU A 519 -1.011 15.127 25.266 1.00 73.62 O ANISOU 332 O GLU A 519 6327 5099 16546 -1248 -278 1097 O ATOM 333 CB GLU A 519 1.218 12.713 25.170 1.00 83.65 C ANISOU 333 CB GLU A 519 8192 6139 17452 -1283 -496 986 C ATOM 334 CG GLU A 519 0.686 12.837 26.599 1.00 93.94 C ANISOU 334 CG GLU A 519 9353 7452 18888 -1321 -171 1188 C ATOM 335 CD GLU A 519 1.311 11.837 27.563 1.00103.77 C ANISOU 335 CD GLU A 519 10797 8581 20049 -1351 -49 1281 C ATOM 336 OE1 GLU A 519 2.522 11.548 27.439 1.00104.80 O ANISOU 336 OE1 GLU A 519 11173 8705 19943 -1270 -113 1162 O ATOM 337 OE2 GLU A 519 0.579 11.325 28.441 1.00106.76 O ANISOU 337 OE2 GLU A 519 11100 8869 20594 -1453 110 1474 O ATOM 338 N LYS A 520 1.093 15.873 24.876 1.00 67.03 N ANISOU 338 N LYS A 520 5764 4449 15254 -1054 -291 836 N ATOM 339 CA LYS A 520 0.826 17.221 25.355 1.00 66.78 C ANISOU 339 CA LYS A 520 5565 4577 15231 -964 -82 852 C ATOM 340 C LYS A 520 0.928 18.213 24.210 1.00 65.59 C ANISOU 340 C LYS A 520 5404 4535 14983 -884 -249 685 C ATOM 341 O LYS A 520 1.788 18.089 23.332 1.00 61.81 O ANISOU 341 O LYS A 520 5094 4077 14315 -847 -432 528 O ATOM 342 CB LYS A 520 1.779 17.601 26.488 1.00 67.30 C ANISOU 342 CB LYS A 520 5699 4742 15130 -870 197 868 C ATOM 343 CG LYS A 520 1.444 16.887 27.791 1.00 75.30 C ANISOU 343 CG LYS A 520 6691 5667 16254 -936 427 1069 C ATOM 344 CD LYS A 520 2.666 16.663 28.672 1.00 75.78 C ANISOU 344 CD LYS A 520 6934 5747 16112 -864 599 1064 C ATOM 345 CE LYS A 520 3.071 17.934 29.407 1.00 77.39 C ANISOU 345 CE LYS A 520 7076 6126 16204 -722 858 1048 C ATOM 346 NZ LYS A 520 4.318 17.740 30.219 1.00 80.37 N ANISOU 346 NZ LYS A 520 7639 6516 16379 -640 1013 1033 N ATOM 347 N LYS A 521 0.013 19.179 24.222 1.00 66.15 N ANISOU 347 N LYS A 521 5292 4665 15178 -857 -185 723 N ATOM 348 CA LYS A 521 -0.045 20.199 23.192 1.00 68.75 C ANISOU 348 CA LYS A 521 5610 5083 15429 -783 -331 585 C ATOM 349 C LYS A 521 0.189 21.578 23.784 1.00 68.02 C ANISOU 349 C LYS A 521 5467 5148 15229 -661 -107 560 C ATOM 350 O LYS A 521 -0.315 21.902 24.865 1.00 62.99 O ANISOU 350 O LYS A 521 4720 4527 14687 -651 134 688 O ATOM 351 CB LYS A 521 -1.387 20.157 22.451 1.00 64.50 C ANISOU 351 CB LYS A 521 4935 4445 15126 -854 -514 628 C ATOM 352 CG LYS A 521 -1.405 19.103 21.349 1.00 74.32 C ANISOU 352 CG LYS A 521 6286 5557 16396 -934 -827 572 C ATOM 353 CD LYS A 521 -2.541 19.292 20.366 1.00 81.42 C ANISOU 353 CD LYS A 521 7078 6377 17480 -969 -1049 567 C ATOM 354 CE LYS A 521 -2.560 18.175 19.324 1.00 84.06 C ANISOU 354 CE LYS A 521 7535 6567 17839 -1044 -1359 519 C ATOM 355 NZ LYS A 521 -2.660 16.810 19.928 1.00 83.09 N ANISOU 355 NZ LYS A 521 7432 6299 17840 -1161 -1342 637 N ATOM 356 N TYR A 522 0.971 22.377 23.070 1.00 56.84 N ANISOU 356 N TYR A 522 4151 3846 13600 -570 -187 395 N ATOM 357 CA TYR A 522 1.206 23.753 23.466 1.00 65.38 C ANISOU 357 CA TYR A 522 5213 5064 14562 -454 -13 351 C ATOM 358 C TYR A 522 0.635 24.728 22.440 1.00 60.80 C ANISOU 358 C TYR A 522 4608 4516 13977 -421 -171 265 C ATOM 359 O TYR A 522 1.341 25.173 21.543 1.00 58.59 O ANISOU 359 O TYR A 522 4440 4312 13509 -370 -301 114 O ATOM 360 CB TYR A 522 2.702 23.980 23.666 1.00 67.63 C ANISOU 360 CB TYR A 522 5642 5464 14591 -369 70 234 C ATOM 361 CG TYR A 522 3.273 23.020 24.681 1.00 59.50 C ANISOU 361 CG TYR A 522 4653 4389 13565 -398 220 319 C ATOM 362 CD1 TYR A 522 3.183 23.287 26.041 1.00 53.84 C ANISOU 362 CD1 TYR A 522 3880 3691 12884 -358 509 441 C ATOM 363 CD2 TYR A 522 3.866 21.836 24.282 1.00 56.83 C ANISOU 363 CD2 TYR A 522 4440 3973 13179 -465 70 281 C ATOM 364 CE1 TYR A 522 3.684 22.412 26.974 1.00 56.14 C ANISOU 364 CE1 TYR A 522 4224 3933 13172 -382 652 528 C ATOM 365 CE2 TYR A 522 4.370 20.948 25.211 1.00 60.09 C ANISOU 365 CE2 TYR A 522 4923 4323 13587 -492 199 361 C ATOM 366 CZ TYR A 522 4.282 21.252 26.558 1.00 57.12 C ANISOU 366 CZ TYR A 522 4474 3974 13255 -451 495 487 C ATOM 367 OH TYR A 522 4.778 20.379 27.496 1.00 57.42 O ANISOU 367 OH TYR A 522 4602 3941 13275 -473 630 576 O ATOM 368 N PRO A 523 -0.661 25.044 22.562 1.00 67.69 N ANISOU 368 N PRO A 523 5336 5326 15057 -456 -157 363 N ATOM 369 CA PRO A 523 -1.315 25.978 21.643 1.00 61.51 C ANISOU 369 CA PRO A 523 4527 4552 14292 -429 -303 293 C ATOM 370 C PRO A 523 -0.863 27.403 21.893 1.00 58.38 C ANISOU 370 C PRO A 523 4200 4286 13696 -322 -164 215 C ATOM 371 O PRO A 523 -0.712 27.783 23.052 1.00 56.37 O ANISOU 371 O PRO A 523 3941 4078 13398 -288 84 281 O ATOM 372 CB PRO A 523 -2.798 25.820 21.984 1.00 59.10 C ANISOU 372 CB PRO A 523 4035 4137 14284 -504 -280 439 C ATOM 373 CG PRO A 523 -2.789 25.481 23.431 1.00 59.85 C ANISOU 373 CG PRO A 523 4073 4239 14428 -521 1 579 C ATOM 374 CD PRO A 523 -1.591 24.570 23.602 1.00 71.47 C ANISOU 374 CD PRO A 523 5668 5724 15762 -524 9 547 C ATOM 375 N CYS A 524 -0.644 28.170 20.828 1.00 62.39 N ANISOU 375 N CYS A 524 4789 4845 14071 -274 -323 80 N ATOM 376 CA CYS A 524 -0.384 29.609 20.943 1.00 60.34 C ANISOU 376 CA CYS A 524 4604 4689 13635 -191 -221 6 C ATOM 377 C CYS A 524 -1.612 30.337 21.435 1.00 50.89 C ANISOU 377 C CYS A 524 3295 3452 12588 -212 -133 98 C ATOM 378 O CYS A 524 -2.718 30.059 20.980 1.00 61.25 O ANISOU 378 O CYS A 524 4482 4663 14126 -269 -264 152 O ATOM 379 CB CYS A 524 0.033 30.191 19.597 1.00 55.88 C ANISOU 379 CB CYS A 524 4143 4180 12909 -150 -428 -148 C ATOM 380 SG CYS A 524 0.347 31.944 19.622 1.00 45.30 S ANISOU 380 SG CYS A 524 2910 2953 11347 -67 -329 -243 S ATOM 381 N ARG A 525 -1.431 31.276 22.356 1.00 53.46 N ANISOU 381 N ARG A 525 3672 3859 12781 -173 81 113 N ATOM 382 CA ARG A 525 -2.562 32.085 22.834 1.00 55.90 C ANISOU 382 CA ARG A 525 3886 4162 13192 -197 169 190 C ATOM 383 C ARG A 525 -3.026 33.142 21.813 1.00 56.93 C ANISOU 383 C ARG A 525 4038 4297 13296 -179 3 90 C ATOM 384 O ARG A 525 -4.077 33.775 22.009 1.00 63.88 O ANISOU 384 O ARG A 525 4818 5159 14296 -204 31 142 O ATOM 385 CB ARG A 525 -2.199 32.787 24.156 1.00 57.93 C ANISOU 385 CB ARG A 525 4212 4528 13269 -171 435 239 C ATOM 386 CG ARG A 525 -1.788 34.273 23.977 1.00 77.84 C ANISOU 386 CG ARG A 525 6878 7168 15528 -131 442 127 C ATOM 387 CD ARG A 525 -1.203 34.937 25.235 1.00 67.55 C ANISOU 387 CD ARG A 525 5682 6003 13982 -111 670 161 C ATOM 388 NE ARG A 525 -0.193 34.112 25.891 1.00 63.75 N ANISOU 388 NE ARG A 525 5275 5528 13419 -92 780 186 N ATOM 389 CZ ARG A 525 0.588 34.520 26.887 1.00 66.13 C ANISOU 389 CZ ARG A 525 5699 5946 13481 -68 946 200 C ATOM 390 NH1 ARG A 525 0.505 35.769 27.340 1.00 68.34 N ANISOU 390 NH1 ARG A 525 6042 6368 13555 -61 1012 190 N ATOM 391 NH2 ARG A 525 1.469 33.677 27.417 1.00 62.66 N ANISOU 391 NH2 ARG A 525 5318 5487 13002 -50 1032 223 N ATOM 392 N TYR A 526 -2.249 33.346 20.742 1.00 53.67 N ANISOU 392 N TYR A 526 3749 3915 12727 -134 -162 -50 N ATOM 393 CA TYR A 526 -2.489 34.478 19.831 1.00 56.39 C ANISOU 393 CA TYR A 526 4149 4284 12995 -103 -295 -153 C ATOM 394 C TYR A 526 -2.989 34.027 18.477 1.00 64.89 C ANISOU 394 C TYR A 526 5177 5268 14212 -112 -576 -194 C ATOM 395 O TYR A 526 -3.546 34.811 17.710 1.00 70.72 O ANISOU 395 O TYR A 526 5914 5984 14973 -96 -710 -247 O ATOM 396 CB TYR A 526 -1.227 35.298 19.620 1.00 50.12 C ANISOU 396 CB TYR A 526 3548 3616 11879 -39 -260 -283 C ATOM 397 CG TYR A 526 -0.674 35.926 20.865 1.00 55.23 C ANISOU 397 CG TYR A 526 4281 4362 12341 -38 -16 -259 C ATOM 398 CD1 TYR A 526 -1.199 37.107 21.372 1.00 53.84 C ANISOU 398 CD1 TYR A 526 4111 4247 12097 -55 76 -239 C ATOM 399 CD2 TYR A 526 0.390 35.345 21.530 1.00 63.41 C ANISOU 399 CD2 TYR A 526 5396 5443 13253 -24 110 -256 C ATOM 400 CE1 TYR A 526 -0.670 37.692 22.513 1.00 56.29 C ANISOU 400 CE1 TYR A 526 4506 4677 12205 -60 277 -210 C ATOM 401 CE2 TYR A 526 0.919 35.921 22.663 1.00 64.68 C ANISOU 401 CE2 TYR A 526 5652 5705 13220 -31 312 -229 C ATOM 402 CZ TYR A 526 0.392 37.089 23.148 1.00 52.23 C ANISOU 402 CZ TYR A 526 4082 4210 11551 -51 388 -202 C ATOM 403 OH TYR A 526 0.917 37.638 24.287 1.00 62.80 O ANISOU 403 OH TYR A 526 5503 5671 12688 -55 568 -166 O ATOM 404 N CYS A 527 -2.767 32.763 18.174 1.00 50.10 N ANISOU 404 N CYS A 527 3275 3342 12417 -143 -676 -172 N ATOM 405 CA CYS A 527 -3.271 32.200 16.937 1.00 56.59 C ANISOU 405 CA CYS A 527 4067 4072 13363 -171 -958 -198 C ATOM 406 C CYS A 527 -3.505 30.705 17.111 1.00 65.47 C ANISOU 406 C CYS A 527 5105 5096 14675 -248 -1011 -107 C ATOM 407 O CYS A 527 -3.472 30.183 18.229 1.00 54.52 O ANISOU 407 O CYS A 527 3651 3704 13361 -280 -818 -8 O ATOM 408 CB CYS A 527 -2.301 32.449 15.786 1.00 50.96 C ANISOU 408 CB CYS A 527 3523 3448 12391 -121 -1116 -340 C ATOM 409 SG CYS A 527 -0.821 31.409 15.879 1.00 53.35 S ANISOU 409 SG CYS A 527 3943 3838 12491 -125 -1079 -384 S ATOM 410 N GLU A 528 -3.704 30.020 15.992 1.00 71.41 N ANISOU 410 N GLU A 528 7017 5537 14580 219 -2730 -846 N ATOM 411 CA GLU A 528 -4.180 28.645 16.006 1.00 75.00 C ANISOU 411 CA GLU A 528 7463 5910 15124 191 -2809 -829 C ATOM 412 C GLU A 528 -3.070 27.599 16.049 1.00 70.25 C ANISOU 412 C GLU A 528 7089 5346 14256 179 -2704 -839 C ATOM 413 O GLU A 528 -3.348 26.419 16.245 1.00 80.67 O ANISOU 413 O GLU A 528 8412 6605 15634 148 -2736 -824 O ATOM 414 CB GLU A 528 -5.066 28.406 14.780 1.00 87.77 C ANISOU 414 CB GLU A 528 9088 7403 16859 195 -3103 -822 C ATOM 415 CG GLU A 528 -4.333 28.571 13.454 1.00103.75 C ANISOU 415 CG GLU A 528 11374 9424 18622 214 -3218 -847 C ATOM 416 CD GLU A 528 -5.255 28.456 12.249 1.00118.11 C ANISOU 416 CD GLU A 528 13199 11114 20563 211 -3522 -830 C ATOM 417 OE1 GLU A 528 -6.385 27.940 12.403 1.00123.80 O ANISOU 417 OE1 GLU A 528 13751 11740 21547 193 -3645 -797 O ATOM 418 OE2 GLU A 528 -4.846 28.877 11.144 1.00122.81 O ANISOU 418 OE2 GLU A 528 13975 11697 20990 226 -3640 -845 O ATOM 419 N LYS A 529 -1.822 28.016 15.861 1.00 59.56 N ANISOU 419 N LYS A 529 5924 4083 12622 204 -2584 -863 N ATOM 420 CA LYS A 529 -0.706 27.066 15.855 1.00 55.09 C ANISOU 420 CA LYS A 529 5566 3546 11819 203 -2487 -878 C ATOM 421 C LYS A 529 -0.542 26.330 17.191 1.00 51.83 C ANISOU 421 C LYS A 529 5076 3162 11454 171 -2320 -849 C ATOM 422 O LYS A 529 -0.801 26.884 18.262 1.00 60.65 O ANISOU 422 O LYS A 529 6024 4328 12690 157 -2192 -824 O ATOM 423 CB LYS A 529 0.603 27.775 15.498 1.00 53.65 C ANISOU 423 CB LYS A 529 5574 3458 11351 241 -2372 -907 C ATOM 424 CG LYS A 529 0.721 28.235 14.045 1.00 52.52 C ANISOU 424 CG LYS A 529 5581 3277 11097 267 -2533 -940 C ATOM 425 CD LYS A 529 2.073 28.909 13.817 1.00 63.30 C ANISOU 425 CD LYS A 529 7129 4739 12185 302 -2392 -966 C ATOM 426 CE LYS A 529 2.312 29.203 12.348 1.00 70.66 C ANISOU 426 CE LYS A 529 8239 5624 12983 320 -2543 -1004 C ATOM 427 NZ LYS A 529 1.117 29.854 11.726 1.00 74.89 N ANISOU 427 NZ LYS A 529 8667 6083 13704 311 -2767 -985 N ATOM 428 N VAL A 530 -0.122 25.072 17.111 1.00 53.94 N ANISOU 428 N VAL A 530 5471 3388 11635 157 -2328 -853 N ATOM 429 CA VAL A 530 0.125 24.245 18.293 1.00 57.88 C ANISOU 429 CA VAL A 530 5933 3900 12159 123 -2195 -820 C ATOM 430 C VAL A 530 1.534 23.676 18.199 1.00 55.33 C ANISOU 430 C VAL A 530 5827 3619 11578 146 -2096 -841 C ATOM 431 O VAL A 530 2.033 23.446 17.098 1.00 53.82 O ANISOU 431 O VAL A 530 5809 3401 11240 178 -2172 -887 O ATOM 432 CB VAL A 530 -0.916 23.106 18.430 1.00 60.91 C ANISOU 432 CB VAL A 530 6231 4167 12746 74 -2321 -794 C ATOM 433 CG1 VAL A 530 -0.715 22.357 19.727 1.00 53.33 C ANISOU 433 CG1 VAL A 530 5226 3215 11821 30 -2185 -751 C ATOM 434 CG2 VAL A 530 -2.334 23.680 18.372 1.00 54.94 C ANISOU 434 CG2 VAL A 530 5254 3356 12264 61 -2438 -777 C ATOM 435 N PHE A 531 2.188 23.496 19.345 1.00 49.59 N ANISOU 435 N PHE A 531 5086 2952 10802 133 -1925 -809 N ATOM 436 CA PHE A 531 3.603 23.142 19.379 1.00 48.46 C ANISOU 436 CA PHE A 531 5124 2858 10429 164 -1815 -824 C ATOM 437 C PHE A 531 3.840 21.951 20.288 1.00 58.55 C ANISOU 437 C PHE A 531 6407 4098 11742 129 -1767 -787 C ATOM 438 O PHE A 531 3.136 21.783 21.287 1.00 68.91 O ANISOU 438 O PHE A 531 7568 5394 13222 75 -1740 -737 O ATOM 439 CB PHE A 531 4.450 24.336 19.861 1.00 51.67 C ANISOU 439 CB PHE A 531 5526 3387 10719 192 -1655 -820 C ATOM 440 CG PHE A 531 4.395 25.527 18.947 1.00 52.61 C ANISOU 440 CG PHE A 531 5672 3543 10775 228 -1698 -855 C ATOM 441 CD1 PHE A 531 3.506 26.570 19.192 1.00 46.25 C ANISOU 441 CD1 PHE A 531 4714 2764 10093 212 -1697 -836 C ATOM 442 CD2 PHE A 531 5.238 25.608 17.847 1.00 46.25 C ANISOU 442 CD2 PHE A 531 5043 2737 9793 277 -1741 -909 C ATOM 443 CE1 PHE A 531 3.458 27.662 18.351 1.00 46.05 C ANISOU 443 CE1 PHE A 531 4723 2762 10012 243 -1751 -862 C ATOM 444 CE2 PHE A 531 5.186 26.683 17.003 1.00 46.04 C ANISOU 444 CE2 PHE A 531 5056 2735 9702 303 -1789 -935 C ATOM 445 CZ PHE A 531 4.286 27.725 17.255 1.00 45.93 C ANISOU 445 CZ PHE A 531 4896 2746 9809 286 -1802 -908 C ATOM 446 N PRO A 532 4.844 21.122 19.954 1.00 60.56 N ANISOU 446 N PRO A 532 6815 4322 11873 161 -1773 -817 N ATOM 447 CA PRO A 532 5.115 19.906 20.725 1.00 58.18 C ANISOU 447 CA PRO A 532 6533 3964 11607 131 -1754 -782 C ATOM 448 C PRO A 532 6.045 20.166 21.906 1.00 58.38 C ANISOU 448 C PRO A 532 6539 4073 11572 129 -1587 -738 C ATOM 449 O PRO A 532 6.160 19.272 22.752 1.00 56.28 O ANISOU 449 O PRO A 532 6266 3763 11354 90 -1567 -691 O ATOM 450 CB PRO A 532 5.777 18.997 19.701 1.00 50.41 C ANISOU 450 CB PRO A 532 5721 2903 10528 177 -1842 -846 C ATOM 451 CG PRO A 532 6.524 19.957 18.815 1.00 51.38 C ANISOU 451 CG PRO A 532 5930 3095 10495 243 -1809 -907 C ATOM 452 CD PRO A 532 5.732 21.234 18.779 1.00 54.09 C ANISOU 452 CD PRO A 532 6160 3504 10888 227 -1806 -889 C ATOM 453 N LEU A 533 6.684 21.344 21.938 1.00 48.59 N ANISOU 453 N LEU A 533 5296 2939 10225 165 -1481 -749 N ATOM 454 CA LEU A 533 7.544 21.796 23.034 1.00 45.24 C ANISOU 454 CA LEU A 533 4850 2604 9735 160 -1318 -705 C ATOM 455 C LEU A 533 7.088 23.159 23.540 1.00 44.14 C ANISOU 455 C LEU A 533 4588 2559 9626 139 -1221 -683 C ATOM 456 O LEU A 533 6.752 24.040 22.760 1.00 52.88 O ANISOU 456 O LEU A 533 5685 3692 10716 166 -1258 -721 O ATOM 457 CB LEU A 533 9.018 21.915 22.598 1.00 44.47 C ANISOU 457 CB LEU A 533 4893 2549 9453 231 -1265 -745 C ATOM 458 CG LEU A 533 10.023 20.764 22.747 1.00 63.85 C ANISOU 458 CG LEU A 533 7451 4951 11857 259 -1267 -748 C ATOM 459 CD1 LEU A 533 9.672 19.576 21.861 1.00 46.71 C ANISOU 459 CD1 LEU A 533 5357 2655 9735 272 -1416 -795 C ATOM 460 CD2 LEU A 533 11.451 21.272 22.452 1.00 51.35 C ANISOU 460 CD2 LEU A 533 5972 3441 10098 330 -1176 -784 C ATOM 461 N ALA A 534 7.139 23.344 24.848 1.00 40.56 N ANISOU 461 N ALA A 534 4691 2460 8259 176 -403 -249 N ATOM 462 CA ALA A 534 6.757 24.586 25.468 1.00 39.46 C ANISOU 462 CA ALA A 534 4417 2550 8027 276 -316 -168 C ATOM 463 C ALA A 534 7.639 25.743 24.971 1.00 54.92 C ANISOU 463 C ALA A 534 6449 4603 9817 358 -296 -384 C ATOM 464 O ALA A 534 7.159 26.882 24.785 1.00 46.27 O ANISOU 464 O ALA A 534 5308 3636 8638 369 -285 -382 O ATOM 465 CB ALA A 534 6.836 24.443 26.982 1.00 39.71 C ANISOU 465 CB ALA A 534 4375 2667 8047 440 -195 5 C ATOM 466 N GLU A 535 8.917 25.455 24.722 1.00 37.71 N ANISOU 466 N GLU A 535 4382 2364 7583 417 -291 -550 N ATOM 467 CA GLU A 535 9.848 26.536 24.406 1.00 41.86 C ANISOU 467 CA GLU A 535 4946 3002 7955 481 -270 -708 C ATOM 468 C GLU A 535 9.608 27.050 22.985 1.00 43.45 C ANISOU 468 C GLU A 535 5193 3187 8131 368 -345 -836 C ATOM 469 O GLU A 535 9.829 28.231 22.709 1.00 47.51 O ANISOU 469 O GLU A 535 5710 3809 8532 381 -335 -906 O ATOM 470 CB GLU A 535 11.305 26.088 24.588 1.00 35.76 C ANISOU 470 CB GLU A 535 4231 2228 7127 587 -235 -798 C ATOM 471 CG GLU A 535 11.754 24.959 23.666 1.00 36.72 C ANISOU 471 CG GLU A 535 4462 2189 7300 574 -272 -889 C ATOM 472 CD GLU A 535 13.227 24.643 23.837 1.00 43.01 C ANISOU 472 CD GLU A 535 5287 3042 8013 726 -212 -947 C ATOM 473 OE1 GLU A 535 13.588 24.139 24.920 1.00 40.37 O ANISOU 473 OE1 GLU A 535 4918 2729 7691 832 -156 -850 O ATOM 474 OE2 GLU A 535 14.026 24.863 22.896 1.00 38.52 O ANISOU 474 OE2 GLU A 535 4762 2514 7360 754 -215 -1067 O ATOM 475 N TYR A 536 9.146 26.164 22.102 1.00 37.86 N ANISOU 475 N TYR A 536 4540 2328 7517 255 -430 -862 N ATOM 476 CA TYR A 536 8.767 26.542 20.745 1.00 36.45 C ANISOU 476 CA TYR A 536 4411 2127 7312 146 -517 -969 C ATOM 477 C TYR A 536 7.607 27.519 20.801 1.00 37.81 C ANISOU 477 C TYR A 536 4463 2425 7479 90 -524 -860 C ATOM 478 O TYR A 536 7.582 28.553 20.117 1.00 36.81 O ANISOU 478 O TYR A 536 4345 2384 7255 86 -529 -939 O ATOM 479 CB TYR A 536 8.344 25.319 19.933 1.00 38.14 C ANISOU 479 CB TYR A 536 4737 2153 7602 23 -634 -991 C ATOM 480 CG TYR A 536 9.422 24.319 19.640 1.00 38.91 C ANISOU 480 CG TYR A 536 5009 2188 7588 110 -609 -1077 C ATOM 481 CD1 TYR A 536 10.705 24.482 20.123 1.00 43.69 C ANISOU 481 CD1 TYR A 536 5613 2881 8106 284 -495 -1122 C ATOM 482 CD2 TYR A 536 9.150 23.192 18.880 1.00 48.69 C ANISOU 482 CD2 TYR A 536 6427 3264 8808 24 -706 -1104 C ATOM 483 CE1 TYR A 536 11.691 23.556 19.852 1.00 46.71 C ANISOU 483 CE1 TYR A 536 6145 3198 8406 401 -460 -1182 C ATOM 484 CE2 TYR A 536 10.128 22.268 18.601 1.00 46.22 C ANISOU 484 CE2 TYR A 536 6314 2863 8385 146 -667 -1180 C ATOM 485 CZ TYR A 536 11.397 22.452 19.093 1.00 51.68 C ANISOU 485 CZ TYR A 536 6978 3650 9008 350 -535 -1213 C ATOM 486 OH TYR A 536 12.385 21.532 18.822 1.00 68.65 O ANISOU 486 OH TYR A 536 9315 5712 11057 511 -482 -1271 O ATOM 487 N ARG A 537 6.640 27.181 21.644 1.00 36.96 N ANISOU 487 N ARG A 537 4238 2338 7468 66 -514 -654 N ATOM 488 CA ARG A 537 5.492 28.036 21.807 1.00 50.05 C ANISOU 488 CA ARG A 537 5763 4146 9109 61 -496 -503 C ATOM 489 C ARG A 537 5.899 29.398 22.363 1.00 47.49 C ANISOU 489 C ARG A 537 5460 3963 8621 231 -387 -535 C ATOM 490 O ARG A 537 5.408 30.409 21.900 1.00 43.48 O ANISOU 490 O ARG A 537 4944 3547 8031 245 -384 -538 O ATOM 491 CB ARG A 537 4.438 27.412 22.715 1.00 43.50 C ANISOU 491 CB ARG A 537 4775 3351 8403 35 -480 -229 C ATOM 492 CG ARG A 537 3.309 28.414 23.029 1.00 47.21 C ANISOU 492 CG ARG A 537 5090 4032 8816 109 -418 -35 C ATOM 493 CD ARG A 537 2.170 27.791 23.795 1.00 52.42 C ANISOU 493 CD ARG A 537 5546 4772 9600 77 -400 285 C ATOM 494 NE ARG A 537 2.602 27.342 25.109 1.00 62.93 N ANISOU 494 NE ARG A 537 6879 6092 10941 216 -290 376 N ATOM 495 CZ ARG A 537 1.784 26.973 26.085 1.00 54.83 C ANISOU 495 CZ ARG A 537 5680 5172 9981 270 -217 677 C ATOM 496 NH1 ARG A 537 0.468 27.023 25.913 1.00 57.90 N ANISOU 496 NH1 ARG A 537 5852 5709 10437 192 -240 941 N ATOM 497 NH2 ARG A 537 2.292 26.586 27.245 1.00 57.23 N ANISOU 497 NH2 ARG A 537 6012 5461 10273 415 -115 734 N ATOM 498 N THR A 538 6.793 29.411 23.345 1.00 40.10 N ANISOU 498 N THR A 538 4573 3034 7631 356 -312 -558 N ATOM 499 CA THR A 538 7.214 30.652 23.976 1.00 34.26 C ANISOU 499 CA THR A 538 3898 2394 6725 495 -242 -590 C ATOM 500 C THR A 538 7.965 31.553 23.002 1.00 37.71 C ANISOU 500 C THR A 538 4441 2830 7056 448 -282 -781 C ATOM 501 O THR A 538 7.697 32.748 22.905 1.00 50.64 O ANISOU 501 O THR A 538 6137 4528 8576 493 -265 -791 O ATOM 502 CB THR A 538 8.101 30.352 25.178 1.00 37.97 C ANISOU 502 CB THR A 538 4402 2867 7158 607 -190 -580 C ATOM 503 OG1 THR A 538 7.339 29.632 26.154 1.00 35.23 O ANISOU 503 OG1 THR A 538 3956 2536 6892 673 -134 -375 O ATOM 504 CG2 THR A 538 8.608 31.600 25.788 1.00 33.65 C ANISOU 504 CG2 THR A 538 3967 2392 6427 715 -162 -631 C ATOM 505 N LYS A 539 8.910 30.985 22.266 1.00 34.74 N ANISOU 505 N LYS A 539 4101 2387 6713 375 -326 -920 N ATOM 506 CA LYS A 539 9.600 31.782 21.249 1.00 43.32 C ANISOU 506 CA LYS A 539 5260 3494 7706 328 -356 -1068 C ATOM 507 C LYS A 539 8.599 32.340 20.231 1.00 39.16 C ANISOU 507 C LYS A 539 4729 2979 7171 263 -393 -1070 C ATOM 508 O LYS A 539 8.665 33.515 19.853 1.00 39.43 O ANISOU 508 O LYS A 539 4824 3064 7094 271 -386 -1114 O ATOM 509 CB LYS A 539 10.684 30.946 20.557 1.00 32.91 C ANISOU 509 CB LYS A 539 3965 2125 6416 301 -377 -1182 C ATOM 510 CG LYS A 539 11.786 30.524 21.520 1.00 48.31 C ANISOU 510 CG LYS A 539 5902 4104 8351 382 -336 -1168 C ATOM 511 CD LYS A 539 12.993 29.836 20.847 1.00 46.70 C ANISOU 511 CD LYS A 539 5713 3896 8134 411 -330 -1255 C ATOM 512 CE LYS A 539 14.050 29.463 21.895 1.00 62.22 C ANISOU 512 CE LYS A 539 7634 5931 10077 505 -288 -1206 C ATOM 513 NZ LYS A 539 15.295 28.813 21.318 1.00 77.04 N ANISOU 513 NZ LYS A 539 9503 7850 11920 582 -258 -1252 N ATOM 514 N HIS A 540 7.665 31.499 19.810 1.00 33.22 N ANISOU 514 N HIS A 540 3911 2179 6533 191 -444 -1008 N ATOM 515 CA HIS A 540 6.623 31.912 18.879 1.00 35.55 C ANISOU 515 CA HIS A 540 4172 2509 6826 122 -498 -981 C ATOM 516 C HIS A 540 5.802 33.098 19.394 1.00 41.66 C ANISOU 516 C HIS A 540 4912 3406 7512 221 -432 -856 C ATOM 517 O HIS A 540 5.569 34.094 18.690 1.00 42.68 O ANISOU 517 O HIS A 540 5086 3586 7544 233 -433 -894 O ATOM 518 CB HIS A 540 5.695 30.728 18.605 1.00 34.97 C ANISOU 518 CB HIS A 540 4017 2369 6900 -1 -590 -888 C ATOM 519 CG HIS A 540 4.508 31.070 17.761 1.00 36.28 C ANISOU 519 CG HIS A 540 4108 2605 7072 -89 -667 -817 C ATOM 520 ND1 HIS A 540 4.600 31.255 16.402 1.00 37.82 N ANISOU 520 ND1 HIS A 540 4381 2774 7215 -164 -752 -958 N ATOM 521 CD2 HIS A 540 3.202 31.235 18.078 1.00 36.75 C ANISOU 521 CD2 HIS A 540 4005 2782 7174 -103 -672 -598 C ATOM 522 CE1 HIS A 540 3.403 31.529 15.917 1.00 36.69 C ANISOU 522 CE1 HIS A 540 4133 2724 7084 -233 -819 -841 C ATOM 523 NE2 HIS A 540 2.539 31.527 16.913 1.00 37.35 N ANISOU 523 NE2 HIS A 540 4056 2906 7227 -198 -770 -612 N ATOM 524 N GLU A 541 5.356 32.983 20.634 1.00 33.91 N ANISOU 524 N GLU A 541 3867 2470 6548 320 -365 -697 N ATOM 525 CA GLU A 541 4.493 33.984 21.210 1.00 40.19 C ANISOU 525 CA GLU A 541 4647 3383 7239 469 -285 -551 C ATOM 526 C GLU A 541 5.252 35.318 21.372 1.00 48.57 C ANISOU 526 C GLU A 541 5906 4432 8114 572 -242 -672 C ATOM 527 O GLU A 541 4.727 36.431 21.079 1.00 40.81 O ANISOU 527 O GLU A 541 4997 3501 7009 658 -211 -646 O ATOM 528 CB GLU A 541 3.935 33.464 22.540 1.00 42.62 C ANISOU 528 CB GLU A 541 4853 3748 7593 580 -210 -343 C ATOM 529 CG GLU A 541 2.959 32.295 22.379 1.00 36.54 C ANISOU 529 CG GLU A 541 3874 3002 7008 452 -264 -162 C ATOM 530 CD GLU A 541 2.249 31.916 23.687 1.00 46.52 C ANISOU 530 CD GLU A 541 5003 4366 8307 579 -168 105 C ATOM 531 OE1 GLU A 541 2.885 32.010 24.761 1.00 46.48 O ANISOU 531 OE1 GLU A 541 5089 4342 8228 729 -84 89 O ATOM 532 OE2 GLU A 541 1.064 31.499 23.643 1.00 48.08 O ANISOU 532 OE2 GLU A 541 4993 4673 8604 525 -182 348 O ATOM 533 N ILE A 542 6.511 35.216 21.791 1.00 45.50 N ANISOU 533 N ILE A 542 5613 3973 7701 553 -252 -796 N ATOM 534 CA ILE A 542 7.261 36.446 21.985 1.00 42.45 C ANISOU 534 CA ILE A 542 5418 3563 7147 599 -247 -893 C ATOM 535 C ILE A 542 7.419 37.068 20.611 1.00 40.91 C ANISOU 535 C ILE A 542 5267 3355 6921 497 -292 -1000 C ATOM 536 O ILE A 542 7.358 38.290 20.460 1.00 32.04 O ANISOU 536 O ILE A 542 4294 2222 5659 544 -282 -1019 O ATOM 537 CB ILE A 542 8.601 36.200 22.683 1.00 37.18 C ANISOU 537 CB ILE A 542 4808 2857 6463 569 -273 -976 C ATOM 538 CG1 ILE A 542 8.317 35.607 24.063 1.00 43.72 C ANISOU 538 CG1 ILE A 542 5598 3707 7307 698 -220 -854 C ATOM 539 CG2 ILE A 542 9.323 37.481 22.880 1.00 39.24 C ANISOU 539 CG2 ILE A 542 5271 3085 6555 567 -306 -1054 C ATOM 540 CD1 ILE A 542 9.487 35.588 25.007 1.00 44.29 C ANISOU 540 CD1 ILE A 542 5749 3764 7314 712 -246 -906 C ATOM 541 N HIS A 543 7.564 36.223 19.595 1.00 36.45 N ANISOU 541 N HIS A 543 4596 2780 6472 372 -341 -1062 N ATOM 542 CA HIS A 543 7.570 36.747 18.237 1.00 31.54 C ANISOU 542 CA HIS A 543 4007 2164 5813 298 -377 -1145 C ATOM 543 C HIS A 543 6.270 37.487 17.922 1.00 43.31 C ANISOU 543 C HIS A 543 5493 3715 7246 371 -355 -1044 C ATOM 544 O HIS A 543 6.312 38.516 17.233 1.00 46.98 O ANISOU 544 O HIS A 543 6061 4185 7605 378 -352 -1090 O ATOM 545 CB HIS A 543 7.806 35.638 17.220 1.00 36.44 C ANISOU 545 CB HIS A 543 4548 2757 6540 189 -438 -1224 C ATOM 546 CG HIS A 543 7.999 36.139 15.828 1.00 39.61 C ANISOU 546 CG HIS A 543 4998 3171 6880 134 -469 -1320 C ATOM 547 ND1 HIS A 543 6.945 36.362 14.967 1.00 54.68 N ANISOU 547 ND1 HIS A 543 6878 5118 8780 118 -505 -1288 N ATOM 548 CD2 HIS A 543 9.119 36.488 15.150 1.00 51.69 C ANISOU 548 CD2 HIS A 543 6590 4705 8346 99 -467 -1424 C ATOM 549 CE1 HIS A 543 7.409 36.812 13.815 1.00 62.42 C ANISOU 549 CE1 HIS A 543 7921 6108 9687 85 -522 -1386 C ATOM 550 NE2 HIS A 543 8.725 36.902 13.900 1.00 60.18 N ANISOU 550 NE2 HIS A 543 7689 5806 9371 75 -492 -1462 N ATOM 551 N HIS A 544 5.124 37.002 18.427 1.00 38.29 N ANISOU 551 N HIS A 544 4730 3143 6675 432 -333 -883 N ATOM 552 CA HIS A 544 3.856 37.738 18.237 1.00 33.61 C ANISOU 552 CA HIS A 544 4102 2657 6012 541 -295 -740 C ATOM 553 C HIS A 544 3.915 39.144 18.826 1.00 49.45 C ANISOU 553 C HIS A 544 6312 4652 7823 724 -210 -725 C ATOM 554 O HIS A 544 3.352 40.101 18.266 1.00 34.14 O ANISOU 554 O HIS A 544 4443 2755 5772 808 -182 -691 O ATOM 555 CB HIS A 544 2.646 37.040 18.887 1.00 34.80 C ANISOU 555 CB HIS A 544 4051 2920 6253 597 -269 -509 C ATOM 556 CG HIS A 544 1.971 36.021 18.023 1.00 46.83 C ANISOU 556 CG HIS A 544 5381 4481 7930 416 -379 -455 C ATOM 557 ND1 HIS A 544 1.215 36.362 16.922 1.00 42.62 N ANISOU 557 ND1 HIS A 544 4783 4036 7374 369 -438 -422 N ATOM 558 CD2 HIS A 544 1.912 34.668 18.116 1.00 36.09 C ANISOU 558 CD2 HIS A 544 3902 3070 6741 264 -460 -422 C ATOM 559 CE1 HIS A 544 0.748 35.261 16.360 1.00 50.41 C ANISOU 559 CE1 HIS A 544 5625 5021 8507 176 -569 -382 C ATOM 560 NE2 HIS A 544 1.151 34.220 17.067 1.00 54.28 N ANISOU 560 NE2 HIS A 544 6092 5413 9117 106 -585 -382 N ATOM 561 N THR A 545 4.506 39.273 20.008 1.00 49.04 N ANISOU 561 N THR A 545 6378 4540 7714 805 -172 -737 N ATOM 562 CA THR A 545 4.435 40.607 20.616 1.00 41.53 C ANISOU 562 CA THR A 545 5679 3549 6552 994 -110 -719 C ATOM 563 C THR A 545 5.419 41.618 20.019 1.00 38.22 C ANISOU 563 C THR A 545 5488 3006 6027 897 -166 -886 C ATOM 564 O THR A 545 5.222 42.834 20.140 1.00 44.77 O ANISOU 564 O THR A 545 6559 3775 6676 1026 -135 -877 O ATOM 565 CB THR A 545 4.667 40.572 22.133 1.00 49.08 C ANISOU 565 CB THR A 545 6743 4473 7433 1138 -65 -673 C ATOM 566 OG1 THR A 545 6.053 40.320 22.396 1.00 33.88 O ANISOU 566 OG1 THR A 545 4890 2446 5538 980 -146 -828 O ATOM 567 CG2 THR A 545 3.735 39.544 22.829 1.00 35.33 C ANISOU 567 CG2 THR A 545 4762 2864 5799 1237 4 -473 C ATOM 568 N GLY A 546 6.478 41.142 19.385 1.00 34.72 N ANISOU 568 N GLY A 546 2812 3234 7145 270 -865 -564 N ATOM 569 CA GLY A 546 7.452 42.049 18.783 1.00 28.74 C ANISOU 569 CA GLY A 546 2084 2551 6284 366 -925 -335 C ATOM 570 C GLY A 546 8.462 42.567 19.775 1.00 27.07 C ANISOU 570 C GLY A 546 2022 2124 6141 371 -811 -252 C ATOM 571 O GLY A 546 9.345 43.380 19.423 1.00 34.84 O ANISOU 571 O GLY A 546 3037 3122 7078 436 -827 -76 O ATOM 572 N GLU A 547 8.363 42.086 21.015 1.00 29.38 N ANISOU 572 N GLU A 547 2385 2249 6527 291 -688 -378 N ATOM 573 CA GLU A 547 9.281 42.495 22.071 1.00 33.65 C ANISOU 573 CA GLU A 547 3044 2739 7003 234 -560 -330 C ATOM 574 C GLU A 547 10.722 42.229 21.652 1.00 36.89 C ANISOU 574 C GLU A 547 3578 3197 7243 270 -567 -257 C ATOM 575 O GLU A 547 10.981 41.271 20.922 1.00 34.98 O ANISOU 575 O GLU A 547 3361 2983 6945 297 -623 -307 O ATOM 576 CB GLU A 547 8.967 41.757 23.379 1.00 30.71 C ANISOU 576 CB GLU A 547 2690 2346 6631 138 -436 -435 C ATOM 577 CG GLU A 547 9.864 42.188 24.557 1.00 23.60 C ANISOU 577 CG GLU A 547 1836 1480 5650 100 -315 -401 C ATOM 578 CD GLU A 547 9.462 41.539 25.858 1.00 34.12 C ANISOU 578 CD GLU A 547 3146 2810 7007 30 -201 -469 C ATOM 579 OE1 GLU A 547 8.589 40.637 25.839 1.00 32.28 O ANISOU 579 OE1 GLU A 547 2895 2551 6818 5 -197 -518 O ATOM 580 OE2 GLU A 547 9.991 41.933 26.910 1.00 37.68 O ANISOU 580 OE2 GLU A 547 3579 3282 7457 -10 -106 -486 O ATOM 581 N ARG A 548 11.653 43.058 22.115 1.00 24.17 N ANISOU 581 N ARG A 548 2021 1605 5558 257 -496 -178 N ATOM 582 CA ARG A 548 13.067 42.874 21.815 1.00 22.66 C ANISOU 582 CA ARG A 548 1937 1461 5210 288 -492 -119 C ATOM 583 C ARG A 548 13.827 42.826 23.112 1.00 36.76 C ANISOU 583 C ARG A 548 3772 3258 6938 234 -367 -150 C ATOM 584 O ARG A 548 14.116 43.867 23.719 1.00 34.90 O ANISOU 584 O ARG A 548 3490 3017 6755 207 -293 -157 O ATOM 585 CB ARG A 548 13.599 43.997 20.930 1.00 25.18 C ANISOU 585 CB ARG A 548 2239 1812 5514 348 -538 20 C ATOM 586 CG ARG A 548 12.786 44.172 19.645 1.00 32.45 C ANISOU 586 CG ARG A 548 3051 2792 6487 430 -680 116 C ATOM 587 CD ARG A 548 13.597 44.845 18.582 1.00 29.18 C ANISOU 587 CD ARG A 548 2627 2482 5979 502 -739 305 C ATOM 588 NE ARG A 548 12.866 45.902 17.930 1.00 50.39 N ANISOU 588 NE ARG A 548 5192 5212 8742 550 -772 495 N ATOM 589 CZ ARG A 548 12.768 46.019 16.617 1.00 62.15 C ANISOU 589 CZ ARG A 548 6575 6922 10118 630 -905 680 C ATOM 590 NH1 ARG A 548 13.373 45.130 15.839 1.00 66.18 N ANISOU 590 NH1 ARG A 548 7090 7649 10408 633 -1011 630 N ATOM 591 NH2 ARG A 548 12.078 47.028 16.096 1.00 59.69 N ANISOU 591 NH2 ARG A 548 6150 6659 9871 682 -909 898 N ATOM 592 N ARG A 549 14.163 41.616 23.539 1.00 23.19 N ANISOU 592 N ARG A 549 2115 1543 5155 226 -333 -170 N ATOM 593 CA ARG A 549 14.680 41.432 24.880 1.00 29.70 C ANISOU 593 CA ARG A 549 2936 2372 5976 196 -225 -168 C ATOM 594 C ARG A 549 16.199 41.458 24.876 1.00 26.66 C ANISOU 594 C ARG A 549 2613 2035 5479 247 -209 -104 C ATOM 595 O ARG A 549 16.838 41.640 25.922 1.00 32.53 O ANISOU 595 O ARG A 549 3323 2894 6144 213 -122 -97 O ATOM 596 CB ARG A 549 14.180 40.114 25.471 1.00 39.10 C ANISOU 596 CB ARG A 549 4127 3514 7214 173 -174 -159 C ATOM 597 CG ARG A 549 12.663 39.964 25.538 1.00 36.06 C ANISOU 597 CG ARG A 549 3669 3085 6946 117 -178 -243 C ATOM 598 CD ARG A 549 12.300 38.546 26.023 1.00 28.17 C ANISOU 598 CD ARG A 549 2676 2018 6011 90 -100 -213 C ATOM 599 NE ARG A 549 12.986 38.282 27.288 1.00 39.16 N ANISOU 599 NE ARG A 549 4054 3437 7387 80 7 -87 N ATOM 600 CZ ARG A 549 13.207 37.076 27.807 1.00 43.61 C ANISOU 600 CZ ARG A 549 4622 3972 7975 88 99 59 C ATOM 601 NH1 ARG A 549 12.769 35.971 27.192 1.00 39.77 N ANISOU 601 NH1 ARG A 549 4157 3331 7621 96 122 39 N ATOM 602 NH2 ARG A 549 13.869 36.983 28.960 1.00 31.97 N ANISOU 602 NH2 ARG A 549 3100 2689 6359 80 184 228 N ATOM 603 N TYR A 550 16.794 41.266 23.703 1.00 20.44 N ANISOU 603 N TYR A 550 1902 1275 4591 297 -285 -68 N ATOM 604 CA TYR A 550 18.253 41.155 23.645 1.00 29.52 C ANISOU 604 CA TYR A 550 3106 2478 5631 351 -272 -15 C ATOM 605 C TYR A 550 18.837 42.477 23.198 1.00 32.45 C ANISOU 605 C TYR A 550 3469 2885 5974 352 -285 -11 C ATOM 606 O TYR A 550 18.529 42.938 22.091 1.00 38.62 O ANISOU 606 O TYR A 550 4253 3651 6769 371 -362 19 O ATOM 607 CB TYR A 550 18.692 40.030 22.694 1.00 20.18 C ANISOU 607 CB TYR A 550 1990 1291 4385 397 -318 -7 C ATOM 608 CG TYR A 550 18.365 38.643 23.179 1.00 29.97 C ANISOU 608 CG TYR A 550 3229 2469 5690 391 -252 4 C ATOM 609 CD1 TYR A 550 19.358 37.800 23.648 1.00 29.71 C ANISOU 609 CD1 TYR A 550 3214 2443 5633 445 -183 98 C ATOM 610 CD2 TYR A 550 17.050 38.180 23.195 1.00 30.47 C ANISOU 610 CD2 TYR A 550 3251 2459 5868 337 -245 -60 C ATOM 611 CE1 TYR A 550 19.065 36.541 24.111 1.00 29.87 C ANISOU 611 CE1 TYR A 550 3212 2378 5757 445 -96 158 C ATOM 612 CE2 TYR A 550 16.749 36.923 23.658 1.00 28.84 C ANISOU 612 CE2 TYR A 550 3029 2170 5758 323 -156 -36 C ATOM 613 CZ TYR A 550 17.758 36.108 24.106 1.00 41.50 C ANISOU 613 CZ TYR A 550 4652 3761 7355 377 -76 86 C ATOM 614 OH TYR A 550 17.450 34.851 24.568 1.00 30.42 O ANISOU 614 OH TYR A 550 3213 2252 6092 369 36 154 O ATOM 615 N GLN A 551 19.688 43.078 24.036 1.00 36.29 N ANISOU 615 N GLN A 551 3926 3468 6394 316 -195 -35 N ATOM 616 CA GLN A 551 20.308 44.385 23.710 1.00 35.28 C ANISOU 616 CA GLN A 551 3770 3338 6294 299 -161 -54 C ATOM 617 C GLN A 551 21.823 44.296 23.646 1.00 29.14 C ANISOU 617 C GLN A 551 3040 2703 5327 313 -137 -43 C ATOM 618 O GLN A 551 22.463 43.790 24.579 1.00 30.55 O ANISOU 618 O GLN A 551 3198 3041 5369 298 -81 -67 O ATOM 619 CB GLN A 551 19.903 45.469 24.733 1.00 30.90 C ANISOU 619 CB GLN A 551 3083 2763 5895 206 -35 -183 C ATOM 620 CG GLN A 551 20.387 46.907 24.361 1.00 26.69 C ANISOU 620 CG GLN A 551 2488 2139 5512 179 44 -216 C ATOM 621 CD GLN A 551 19.856 47.960 25.323 1.00 33.35 C ANISOU 621 CD GLN A 551 3162 2913 6596 75 200 -403 C ATOM 622 OE1 GLN A 551 19.528 47.659 26.482 1.00 28.83 O ANISOU 622 OE1 GLN A 551 2509 2475 5970 -7 264 -549 O ATOM 623 NE2 GLN A 551 19.766 49.205 24.853 1.00 29.26 N ANISOU 623 NE2 GLN A 551 2564 2218 6336 64 277 -393 N ATOM 624 N CYS A 552 22.387 44.776 22.534 1.00 30.93 N ANISOU 624 N CYS A 552 3313 2905 5534 346 -181 14 N ATOM 625 CA CYS A 552 23.832 44.903 22.382 1.00 31.15 C ANISOU 625 CA CYS A 552 3374 3060 5403 348 -149 5 C ATOM 626 C CYS A 552 24.298 46.014 23.298 1.00 35.58 C ANISOU 626 C CYS A 552 3833 3666 6022 257 -4 -117 C ATOM 627 O CYS A 552 23.694 47.086 23.314 1.00 29.51 O ANISOU 627 O CYS A 552 2986 2749 5480 210 64 -153 O ATOM 628 CB CYS A 552 24.212 45.215 20.933 1.00 28.04 C ANISOU 628 CB CYS A 552 3034 2647 4975 387 -221 102 C ATOM 629 SG CYS A 552 25.881 45.848 20.735 1.00 29.21 S ANISOU 629 SG CYS A 552 3193 2913 4991 359 -146 75 S ATOM 630 N LEU A 553 25.371 45.786 24.049 1.00 25.34 N ANISOU 630 N LEU A 553 2506 2581 4543 230 58 -195 N ATOM 631 CA LEU A 553 25.786 46.768 25.048 1.00 38.25 C ANISOU 631 CA LEU A 553 3995 4331 6207 111 214 -385 C ATOM 632 C LEU A 553 26.848 47.661 24.460 1.00 43.35 C ANISOU 632 C LEU A 553 4637 4967 6869 77 284 -435 C ATOM 633 O LEU A 553 27.276 48.627 25.087 1.00 51.51 O ANISOU 633 O LEU A 553 5534 6059 7979 -39 442 -635 O ATOM 634 CB LEU A 553 26.295 46.097 26.328 1.00 34.77 C ANISOU 634 CB LEU A 553 3462 4220 5528 82 255 -450 C ATOM 635 CG LEU A 553 25.210 45.368 27.134 1.00 43.56 C ANISOU 635 CG LEU A 553 4537 5367 6647 84 232 -401 C ATOM 636 CD1 LEU A 553 25.738 44.774 28.462 1.00 44.16 C ANISOU 636 CD1 LEU A 553 4477 5843 6460 53 283 -403 C ATOM 637 CD2 LEU A 553 24.070 46.309 27.389 1.00 38.11 C ANISOU 637 CD2 LEU A 553 3760 4507 6214 -10 305 -543 C ATOM 638 N ALA A 554 27.247 47.355 23.234 1.00 40.18 N ANISOU 638 N ALA A 554 4363 4498 6405 162 181 -278 N ATOM 639 CA ALA A 554 28.264 48.157 22.566 1.00 37.98 C ANISOU 639 CA ALA A 554 4088 4212 6132 130 245 -289 C ATOM 640 C ALA A 554 27.690 49.384 21.869 1.00 44.97 C ANISOU 640 C ALA A 554 4934 4827 7326 104 312 -208 C ATOM 641 O ALA A 554 28.380 50.395 21.750 1.00 51.40 O ANISOU 641 O ALA A 554 5682 5584 8264 31 453 -267 O ATOM 642 CB ALA A 554 29.034 47.293 21.564 1.00 35.56 C ANISOU 642 CB ALA A 554 3907 4003 5601 218 120 -167 C ATOM 643 N CYS A 555 26.438 49.300 21.405 1.00 41.28 N ANISOU 643 N CYS A 555 4486 4194 7006 166 224 -57 N ATOM 644 CA CYS A 555 25.811 50.420 20.685 1.00 37.79 C ANISOU 644 CA CYS A 555 3979 3502 6876 176 276 103 C ATOM 645 C CYS A 555 24.331 50.600 21.063 1.00 38.81 C ANISOU 645 C CYS A 555 4031 3458 7257 194 270 117 C ATOM 646 O CYS A 555 23.723 51.595 20.695 1.00 38.33 O ANISOU 646 O CYS A 555 3874 3174 7517 208 341 242 O ATOM 647 CB CYS A 555 25.912 50.204 19.175 1.00 29.64 C ANISOU 647 CB CYS A 555 3029 2516 5718 264 136 380 C ATOM 648 SG CYS A 555 24.817 48.839 18.622 1.00 35.46 S ANISOU 648 SG CYS A 555 3842 3364 6266 361 -97 474 S ATOM 649 N GLY A 556 23.743 49.626 21.761 1.00 31.17 N ANISOU 649 N GLY A 556 3095 2592 6156 200 191 15 N ATOM 650 CA GLY A 556 22.433 49.808 22.368 1.00 23.23 C ANISOU 650 CA GLY A 556 1998 1451 5376 187 215 -42 C ATOM 651 C GLY A 556 21.270 49.227 21.580 1.00 28.40 C ANISOU 651 C GLY A 556 2704 2108 5979 269 44 143 C ATOM 652 O GLY A 556 20.129 49.232 22.046 1.00 25.00 O ANISOU 652 O GLY A 556 2212 1653 5634 240 45 93 O ATOM 653 N LYS A 557 21.555 48.715 20.387 1.00 24.54 N ANISOU 653 N LYS A 557 2304 1691 5329 354 -94 323 N ATOM 654 CA LYS A 557 20.502 48.188 19.522 1.00 26.80 C ANISOU 654 CA LYS A 557 2601 2038 5543 413 -245 457 C ATOM 655 C LYS A 557 19.866 46.940 20.111 1.00 28.92 C ANISOU 655 C LYS A 557 2915 2358 5714 406 -310 320 C ATOM 656 O LYS A 557 20.563 46.097 20.669 1.00 25.89 O ANISOU 656 O LYS A 557 2598 2029 5211 402 -302 214 O ATOM 657 CB LYS A 557 21.059 47.864 18.135 1.00 35.36 C ANISOU 657 CB LYS A 557 3723 3252 6459 490 -372 638 C ATOM 658 CG LYS A 557 21.326 49.085 17.265 1.00 40.55 C ANISOU 658 CG LYS A 557 4307 3879 7223 514 -331 884 C ATOM 659 CD LYS A 557 21.185 48.685 15.815 1.00 51.64 C ANISOU 659 CD LYS A 557 5689 5525 8409 578 -497 1093 C ATOM 660 CE LYS A 557 22.417 48.986 15.020 1.00 57.30 C ANISOU 660 CE LYS A 557 6436 6381 8953 564 -480 1210 C ATOM 661 NZ LYS A 557 22.541 50.443 14.776 1.00 55.92 N ANISOU 661 NZ LYS A 557 6159 6037 9054 587 -360 1482 N ATOM 662 N SER A 558 18.548 46.804 19.968 1.00 34.32 N ANISOU 662 N SER A 558 3550 3029 6461 409 -365 339 N ATOM 663 CA SER A 558 17.854 45.649 20.519 1.00 23.62 C ANISOU 663 CA SER A 558 2221 1694 5058 392 -404 215 C ATOM 664 C SER A 558 17.416 44.621 19.455 1.00 38.26 C ANISOU 664 C SER A 558 4083 3621 6834 457 -555 246 C ATOM 665 O SER A 558 17.255 44.971 18.282 1.00 36.21 O ANISOU 665 O SER A 558 3760 3446 6553 515 -655 385 O ATOM 666 CB SER A 558 16.655 46.132 21.322 1.00 36.53 C ANISOU 666 CB SER A 558 3763 3253 6862 333 -341 148 C ATOM 667 OG SER A 558 17.106 46.953 22.382 1.00 36.81 O ANISOU 667 OG SER A 558 3743 3238 7003 266 -196 52 O ATOM 668 N PHE A 559 17.231 43.357 19.870 1.00 23.50 N ANISOU 668 N PHE A 559 2255 1745 4929 442 -562 119 N ATOM 669 CA PHE A 559 16.919 42.254 18.943 1.00 27.15 C ANISOU 669 CA PHE A 559 2712 2312 5290 446 -651 51 C ATOM 670 C PHE A 559 15.989 41.256 19.607 1.00 25.75 C ANISOU 670 C PHE A 559 2521 2040 5223 407 -616 -79 C ATOM 671 O PHE A 559 15.937 41.137 20.847 1.00 22.20 O ANISOU 671 O PHE A 559 2099 1489 4846 375 -518 -95 O ATOM 672 CB PHE A 559 18.197 41.544 18.473 1.00 35.16 C ANISOU 672 CB PHE A 559 3806 3421 6131 452 -646 10 C ATOM 673 CG PHE A 559 19.219 42.477 17.900 1.00 26.81 C ANISOU 673 CG PHE A 559 2769 2460 4956 477 -662 131 C ATOM 674 CD1 PHE A 559 19.215 42.788 16.542 1.00 33.22 C ANISOU 674 CD1 PHE A 559 3518 3468 5637 491 -760 210 C ATOM 675 CD2 PHE A 559 20.134 43.100 18.722 1.00 22.81 C ANISOU 675 CD2 PHE A 559 2316 1886 4464 475 -570 170 C ATOM 676 CE1 PHE A 559 20.137 43.700 16.000 1.00 23.99 C ANISOU 676 CE1 PHE A 559 2357 2384 4373 509 -760 362 C ATOM 677 CE2 PHE A 559 21.071 43.990 18.184 1.00 25.01 C ANISOU 677 CE2 PHE A 559 2604 2233 4666 485 -562 271 C ATOM 678 CZ PHE A 559 21.051 44.293 16.818 1.00 22.25 C ANISOU 678 CZ PHE A 559 2208 2037 4211 505 -654 385 C ATOM 679 N ILE A 560 15.238 40.547 18.779 1.00 32.42 N ANISOU 679 N ILE A 560 3299 2963 6056 389 -682 -180 N ATOM 680 CA ILE A 560 14.177 39.709 19.269 1.00 28.14 C ANISOU 680 CA ILE A 560 2716 2322 5656 339 -642 -311 C ATOM 681 C ILE A 560 14.696 38.337 19.740 1.00 27.60 C ANISOU 681 C ILE A 560 2710 2137 5638 312 -533 -406 C ATOM 682 O ILE A 560 13.970 37.586 20.383 1.00 51.50 O ANISOU 682 O ILE A 560 5714 5033 8819 269 -455 -475 O ATOM 683 CB ILE A 560 13.091 39.524 18.193 1.00 26.31 C ANISOU 683 CB ILE A 560 2344 2247 5404 315 -742 -415 C ATOM 684 CG1 ILE A 560 13.629 38.726 17.005 1.00 40.14 C ANISOU 684 CG1 ILE A 560 4060 4189 7004 287 -778 -557 C ATOM 685 CG2 ILE A 560 12.543 40.862 17.746 1.00 39.25 C ANISOU 685 CG2 ILE A 560 3888 3997 7028 372 -845 -245 C ATOM 686 CD1 ILE A 560 12.504 38.192 16.085 1.00 41.47 C ANISOU 686 CD1 ILE A 560 4049 4561 7147 222 -843 -761 C ATOM 687 N ASN A 561 15.944 38.009 19.443 1.00 25.31 N ANISOU 687 N ASN A 561 2485 1881 5250 342 -512 -391 N ATOM 688 CA ASN A 561 16.491 36.759 19.977 1.00 31.09 C ANISOU 688 CA ASN A 561 3255 2468 6091 344 -389 -425 C ATOM 689 C ASN A 561 18.020 36.711 20.017 1.00 35.29 C ANISOU 689 C ASN A 561 3860 3034 6514 405 -361 -339 C ATOM 690 O ASN A 561 18.698 37.667 19.636 1.00 39.08 O ANISOU 690 O ASN A 561 4374 3654 6821 429 -432 -274 O ATOM 691 CB ASN A 561 15.951 35.577 19.180 1.00 25.07 C ANISOU 691 CB ASN A 561 2406 1662 5458 288 -354 -657 C ATOM 692 CG ASN A 561 16.337 35.632 17.731 1.00 33.46 C ANISOU 692 CG ASN A 561 3409 2945 6359 268 -442 -810 C ATOM 693 OD1 ASN A 561 17.401 36.149 17.370 1.00 49.69 O ANISOU 693 OD1 ASN A 561 5519 5120 8240 313 -489 -725 O ATOM 694 ND2 ASN A 561 15.494 35.095 16.886 1.00 27.50 N ANISOU 694 ND2 ASN A 561 2522 2286 5642 187 -457 -1052 N ATOM 695 N TYR A 562 18.551 35.589 20.491 1.00 37.41 N ANISOU 695 N TYR A 562 4142 3218 6852 412 -240 -313 N ATOM 696 CA TYR A 562 19.981 35.412 20.647 1.00 23.23 C ANISOU 696 CA TYR A 562 2394 1458 4973 479 -201 -220 C ATOM 697 C TYR A 562 20.708 35.454 19.320 1.00 43.34 C ANISOU 697 C TYR A 562 4927 4069 7470 501 -269 -376 C ATOM 698 O TYR A 562 21.802 35.985 19.224 1.00 38.64 O ANISOU 698 O TYR A 562 4380 3594 6709 542 -299 -305 O ATOM 699 CB TYR A 562 20.308 34.060 21.334 1.00 32.71 C ANISOU 699 CB TYR A 562 3578 2556 6294 492 -51 -133 C ATOM 700 CG TYR A 562 21.785 33.907 21.639 1.00 33.29 C ANISOU 700 CG TYR A 562 3678 2680 6290 582 -15 -1 C ATOM 701 CD1 TYR A 562 22.306 34.257 22.888 1.00 24.00 C ANISOU 701 CD1 TYR A 562 2509 1595 5015 636 12 229 C ATOM 702 CD2 TYR A 562 22.667 33.466 20.665 1.00 25.04 C ANISOU 702 CD2 TYR A 562 2620 1616 5280 615 -11 -129 C ATOM 703 CE1 TYR A 562 23.663 34.146 23.154 1.00 24.16 C ANISOU 703 CE1 TYR A 562 2522 1698 4958 730 35 350 C ATOM 704 CE2 TYR A 562 24.019 33.372 20.916 1.00 28.39 C ANISOU 704 CE2 TYR A 562 3056 2098 5634 704 16 -16 C ATOM 705 CZ TYR A 562 24.516 33.700 22.158 1.00 30.71 C ANISOU 705 CZ TYR A 562 3358 2493 5816 765 35 232 C ATOM 706 OH TYR A 562 25.894 33.567 22.373 1.00 28.12 O ANISOU 706 OH TYR A 562 3011 2254 5419 864 57 339 O ATOM 707 N AGLN A 563 20.102 34.849 18.307 0.48 40.46 N ANISOU 707 N AGLN A 563 4482 3707 7182 438 -278 -606 N ATOM 708 N BGLN A 563 20.126 34.854 18.292 0.52 40.60 N ANISOU 708 N BGLN A 563 4501 3729 7197 439 -279 -607 N ATOM 709 CA AGLN A 563 20.738 34.714 17.006 0.48 34.83 C ANISOU 709 CA AGLN A 563 3721 3167 6346 409 -320 -794 C ATOM 710 CA BGLN A 563 20.839 34.739 17.028 0.52 34.76 C ANISOU 710 CA BGLN A 563 3718 3160 6328 415 -320 -783 C ATOM 711 C AGLN A 563 20.983 36.083 16.362 0.48 35.58 C ANISOU 711 C AGLN A 563 3845 3537 6136 405 -467 -700 C ATOM 712 C BGLN A 563 21.003 36.105 16.347 0.52 35.84 C ANISOU 712 C BGLN A 563 3879 3575 6163 406 -469 -698 C ATOM 713 O AGLN A 563 22.065 36.345 15.846 0.48 37.34 O ANISOU 713 O AGLN A 563 4091 3896 6200 423 -489 -694 O ATOM 714 O BGLN A 563 22.054 36.387 15.784 0.52 37.40 O ANISOU 714 O BGLN A 563 4096 3918 6195 420 -496 -696 O ATOM 715 CB AGLN A 563 19.875 33.834 16.096 0.48 31.83 C ANISOU 715 CB AGLN A 563 3197 2804 6091 309 -289 -1111 C ATOM 716 CB BGLN A 563 20.119 33.755 16.108 0.52 32.36 C ANISOU 716 CB BGLN A 563 3272 2858 6163 320 -276 -1107 C ATOM 717 CG AGLN A 563 19.854 32.351 16.467 0.48 43.84 C ANISOU 717 CG AGLN A 563 4655 4014 7988 302 -96 -1254 C ATOM 718 CG BGLN A 563 20.759 33.608 14.748 0.52 35.53 C ANISOU 718 CG BGLN A 563 3582 3514 6402 262 -311 -1347 C ATOM 719 CD AGLN A 563 19.062 32.029 17.737 0.48 45.46 C ANISOU 719 CD AGLN A 563 4900 4021 8352 307 -9 -1039 C ATOM 720 CD BGLN A 563 20.078 34.467 13.695 0.52 40.82 C ANISOU 720 CD BGLN A 563 4167 4564 6779 189 -472 -1399 C ATOM 721 OE1AGLN A 563 18.185 32.799 18.176 0.48 27.93 O ANISOU 721 OE1AGLN A 563 2714 1834 6065 300 -92 -941 O ATOM 722 OE1BGLN A 563 18.875 34.318 13.436 0.52 41.66 O ANISOU 722 OE1BGLN A 563 4165 4739 6924 119 -498 -1527 O ATOM 723 NE2AGLN A 563 19.377 30.882 18.340 0.48 30.33 N ANISOU 723 NE2AGLN A 563 2964 1964 6597 306 159 -936 N ATOM 724 NE2BGLN A 563 20.841 35.376 13.084 0.52 36.60 N ANISOU 724 NE2BGLN A 563 3660 4294 5950 208 -576 -1275 N ATOM 725 N PHE A 564 19.981 36.960 16.402 1.00 26.42 N ANISOU 725 N PHE A 564 2671 2442 4926 387 -552 -609 N ATOM 726 CA PHE A 564 20.110 38.277 15.776 1.00 29.82 C ANISOU 726 CA PHE A 564 3099 3090 5141 395 -667 -467 C ATOM 727 C PHE A 564 21.123 39.115 16.500 1.00 23.85 C ANISOU 727 C PHE A 564 2451 2276 4335 450 -636 -278 C ATOM 728 O PHE A 564 21.900 39.840 15.881 1.00 34.94 O ANISOU 728 O PHE A 564 3867 3834 5575 456 -677 -201 O ATOM 729 CB PHE A 564 18.775 38.998 15.735 1.00 30.54 C ANISOU 729 CB PHE A 564 3121 3219 5263 384 -743 -386 C ATOM 730 CG PHE A 564 17.875 38.512 14.639 1.00 39.62 C ANISOU 730 CG PHE A 564 4117 4589 6350 321 -815 -562 C ATOM 731 CD1 PHE A 564 18.174 38.783 13.316 1.00 40.75 C ANISOU 731 CD1 PHE A 564 4157 5084 6244 293 -907 -578 C ATOM 732 CD2 PHE A 564 16.736 37.784 14.932 1.00 45.00 C ANISOU 732 CD2 PHE A 564 4729 5168 7200 274 -782 -722 C ATOM 733 CE1 PHE A 564 17.350 38.339 12.303 1.00 59.72 C ANISOU 733 CE1 PHE A 564 6370 7785 8537 217 -974 -767 C ATOM 734 CE2 PHE A 564 15.908 37.336 13.924 1.00 51.90 C ANISOU 734 CE2 PHE A 564 5426 6293 8001 197 -839 -931 C ATOM 735 CZ PHE A 564 16.213 37.610 12.610 1.00 58.35 C ANISOU 735 CZ PHE A 564 6120 7510 8539 166 -938 -963 C ATOM 736 N MET A 565 21.127 38.980 17.824 1.00 23.57 N ANISOU 736 N MET A 565 2471 2050 4433 476 -552 -214 N ATOM 737 CA MET A 565 22.024 39.754 18.679 1.00 28.40 C ANISOU 737 CA MET A 565 3146 2653 4993 506 -504 -85 C ATOM 738 C MET A 565 23.453 39.283 18.404 1.00 39.22 C ANISOU 738 C MET A 565 4552 4096 6252 537 -474 -116 C ATOM 739 O MET A 565 24.319 40.087 18.114 1.00 35.26 O ANISOU 739 O MET A 565 4075 3706 5615 538 -488 -66 O ATOM 740 CB MET A 565 21.641 39.570 20.173 1.00 26.15 C ANISOU 740 CB MET A 565 2864 2242 4830 508 -419 -32 C ATOM 741 CG MET A 565 22.695 40.083 21.184 1.00 28.84 C ANISOU 741 CG MET A 565 3222 2652 5082 522 -349 46 C ATOM 742 SD MET A 565 24.155 39.015 21.368 1.00 33.97 S ANISOU 742 SD MET A 565 3892 3361 5654 595 -294 75 S ATOM 743 CE MET A 565 23.446 37.543 22.114 1.00 39.74 C ANISOU 743 CE MET A 565 4583 3931 6586 629 -219 131 C ATOM 744 N SER A 566 23.690 37.973 18.499 1.00 27.14 N ANISOU 744 N SER A 566 3010 2483 4819 564 -416 -198 N ATOM 745 CA SER A 566 25.021 37.381 18.234 1.00 32.07 C ANISOU 745 CA SER A 566 3641 3151 5392 609 -375 -241 C ATOM 746 C SER A 566 25.539 37.752 16.850 1.00 28.08 C ANISOU 746 C SER A 566 3123 2838 4710 568 -446 -349 C ATOM 747 O SER A 566 26.686 38.151 16.690 1.00 39.41 O ANISOU 747 O SER A 566 4586 4385 6003 585 -443 -321 O ATOM 748 CB SER A 566 24.971 35.851 18.370 1.00 24.97 C ANISOU 748 CB SER A 566 2689 2072 4724 644 -279 -324 C ATOM 749 OG SER A 566 26.223 35.236 18.077 1.00 37.86 O ANISOU 749 OG SER A 566 4303 3721 6363 698 -226 -376 O ATOM 750 N SER A 567 24.691 37.585 15.843 1.00 30.48 N ANISOU 750 N SER A 567 3359 3222 5001 505 -506 -478 N ATOM 751 CA SER A 567 25.070 37.924 14.480 1.00 37.63 C ANISOU 751 CA SER A 567 4211 4396 5691 451 -578 -564 C ATOM 752 C SER A 567 25.454 39.408 14.396 1.00 33.95 C ANISOU 752 C SER A 567 3795 4053 5051 457 -635 -344 C ATOM 753 O SER A 567 26.466 39.776 13.785 1.00 36.55 O ANISOU 753 O SER A 567 4130 4548 5209 443 -643 -334 O ATOM 754 CB SER A 567 23.921 37.596 13.528 1.00 38.62 C ANISOU 754 CB SER A 567 4211 4666 5797 373 -640 -720 C ATOM 755 OG SER A 567 24.380 37.433 12.199 1.00 58.24 O ANISOU 755 OG SER A 567 6591 7463 8074 302 -680 -887 O ATOM 756 N HIS A 568 24.663 40.252 15.059 1.00 36.06 N ANISOU 756 N HIS A 568 4086 4213 5403 472 -649 -178 N ATOM 757 CA HIS A 568 24.960 41.689 15.110 1.00 35.78 C ANISOU 757 CA HIS A 568 4074 4210 5310 475 -655 23 C ATOM 758 C HIS A 568 26.327 41.960 15.698 1.00 37.46 C ANISOU 758 C HIS A 568 4356 4400 5476 490 -574 33 C ATOM 759 O HIS A 568 27.164 42.616 15.092 1.00 29.90 O ANISOU 759 O HIS A 568 3402 3572 4388 470 -573 90 O ATOM 760 CB HIS A 568 23.938 42.456 15.936 1.00 23.63 C ANISOU 760 CB HIS A 568 2526 2501 3949 486 -640 141 C ATOM 761 CG HIS A 568 24.408 43.824 16.322 1.00 29.22 C ANISOU 761 CG HIS A 568 3246 3150 4706 484 -577 286 C ATOM 762 ND1 HIS A 568 24.393 44.887 15.439 1.00 29.00 N ANISOU 762 ND1 HIS A 568 3164 3201 4655 481 -604 469 N ATOM 763 CD2 HIS A 568 24.889 44.313 17.491 1.00 20.43 C ANISOU 763 CD2 HIS A 568 2161 1918 3683 472 -470 265 C ATOM 764 CE1 HIS A 568 24.886 45.964 16.036 1.00 30.72 C ANISOU 764 CE1 HIS A 568 3385 3288 4997 467 -495 539 C ATOM 765 NE2 HIS A 568 25.175 45.646 17.283 1.00 27.03 N ANISOU 765 NE2 HIS A 568 2962 2723 4587 451 -415 385 N ATOM 766 N ILE A 569 26.551 41.464 16.902 1.00 26.07 N ANISOU 766 N ILE A 569 2949 2826 4129 522 -502 -9 N ATOM 767 CA ILE A 569 27.778 41.784 17.581 1.00 24.06 C ANISOU 767 CA ILE A 569 2724 2607 3811 533 -427 0 C ATOM 768 C ILE A 569 28.986 41.242 16.832 1.00 34.95 C ANISOU 768 C ILE A 569 4111 4122 5045 547 -432 -84 C ATOM 769 O ILE A 569 29.971 41.956 16.643 1.00 44.86 O ANISOU 769 O ILE A 569 5378 5484 6185 524 -404 -66 O ATOM 770 CB ILE A 569 27.729 41.248 18.991 1.00 20.31 C ANISOU 770 CB ILE A 569 2243 2053 3422 569 -360 2 C ATOM 771 CG1 ILE A 569 26.610 41.967 19.718 1.00 18.88 C ANISOU 771 CG1 ILE A 569 2036 1773 3365 531 -343 50 C ATOM 772 CG2 ILE A 569 29.046 41.488 19.706 1.00 25.48 C ANISOU 772 CG2 ILE A 569 2885 2830 3964 581 -290 0 C ATOM 773 CD1 ILE A 569 26.652 41.812 21.233 1.00 28.83 C ANISOU 773 CD1 ILE A 569 3255 3050 4650 532 -262 60 C ATOM 774 N LYS A 570 28.920 39.995 16.376 1.00 29.70 N ANISOU 774 N LYS A 570 3423 3446 4415 572 -448 -202 N ATOM 775 CA LYS A 570 30.060 39.436 15.632 1.00 33.43 C ANISOU 775 CA LYS A 570 3876 4043 4783 578 -436 -326 C ATOM 776 C LYS A 570 30.340 40.273 14.389 1.00 38.94 C ANISOU 776 C LYS A 570 4560 4958 5279 503 -493 -322 C ATOM 777 O LYS A 570 31.477 40.628 14.105 1.00 50.10 O ANISOU 777 O LYS A 570 5983 6498 6555 489 -469 -334 O ATOM 778 CB LYS A 570 29.809 37.979 15.237 1.00 32.59 C ANISOU 778 CB LYS A 570 3707 3859 4817 597 -414 -504 C ATOM 779 CG LYS A 570 29.940 36.980 16.394 1.00 39.41 C ANISOU 779 CG LYS A 570 4560 4510 5902 695 -324 -460 C ATOM 780 CD LYS A 570 29.649 35.536 15.936 1.00 43.06 C ANISOU 780 CD LYS A 570 4935 4824 6602 706 -259 -650 C ATOM 781 CE LYS A 570 29.876 34.522 17.061 1.00 37.86 C ANISOU 781 CE LYS A 570 4242 3931 6211 825 -145 -529 C ATOM 782 NZ LYS A 570 29.517 33.119 16.663 1.00 44.09 N ANISOU 782 NZ LYS A 570 4925 4493 7335 831 -37 -714 N ATOM 783 N SER A 571 29.290 40.614 13.663 1.00 31.21 N ANISOU 783 N SER A 571 3541 4046 4272 455 -567 -278 N ATOM 784 CA SER A 571 29.477 41.296 12.386 1.00 33.64 C ANISOU 784 CA SER A 571 3794 4621 4365 389 -625 -222 C ATOM 785 C SER A 571 29.897 42.775 12.487 1.00 41.01 C ANISOU 785 C SER A 571 4765 5561 5256 378 -599 15 C ATOM 786 O SER A 571 30.751 43.230 11.751 1.00 41.12 O ANISOU 786 O SER A 571 4762 5761 5101 336 -590 54 O ATOM 787 CB SER A 571 28.186 41.206 11.591 1.00 29.62 C ANISOU 787 CB SER A 571 3188 4244 3823 352 -716 -212 C ATOM 788 OG SER A 571 28.309 41.931 10.393 1.00 55.98 O ANISOU 788 OG SER A 571 6442 7901 6925 296 -778 -84 O ATOM 789 N VAL A 572 29.234 43.517 13.366 1.00 46.77 N ANISOU 789 N VAL A 572 5524 6082 6166 405 -568 157 N ATOM 790 CA VAL A 572 29.367 44.965 13.479 1.00 37.45 C ANISOU 790 CA VAL A 572 4340 4837 5053 386 -509 365 C ATOM 791 C VAL A 572 30.507 45.325 14.417 1.00 33.36 C ANISOU 791 C VAL A 572 3872 4231 4571 373 -389 286 C ATOM 792 O VAL A 572 31.243 46.261 14.160 1.00 47.24 O ANISOU 792 O VAL A 572 5619 6020 6310 330 -317 368 O ATOM 793 CB VAL A 572 28.060 45.637 14.020 1.00 31.20 C ANISOU 793 CB VAL A 572 3515 3843 4495 410 -506 506 C ATOM 794 CG1 VAL A 572 28.304 47.148 14.357 1.00 23.80 C ANISOU 794 CG1 VAL A 572 2552 2749 3742 387 -383 672 C ATOM 795 CG2 VAL A 572 26.902 45.506 13.035 1.00 24.34 C ANISOU 795 CG2 VAL A 572 2560 3109 3579 424 -627 625 C ATOM 796 N HIS A 573 30.639 44.556 15.497 1.00 22.37 N ANISOU 796 N HIS A 573 2513 2759 3229 409 -362 138 N ATOM 797 CA HIS A 573 31.580 44.821 16.566 1.00 21.47 C ANISOU 797 CA HIS A 573 2404 2631 3123 399 -257 54 C ATOM 798 C HIS A 573 32.792 43.862 16.608 1.00 35.04 C ANISOU 798 C HIS A 573 4134 4493 4686 436 -256 -77 C ATOM 799 O HIS A 573 33.591 43.924 17.559 1.00 36.04 O ANISOU 799 O HIS A 573 4236 4673 4784 442 -181 -142 O ATOM 800 CB HIS A 573 30.840 44.769 17.906 1.00 19.53 C ANISOU 800 CB HIS A 573 2138 2256 3028 413 -217 29 C ATOM 801 CG HIS A 573 29.737 45.773 18.028 1.00 40.41 C ANISOU 801 CG HIS A 573 4746 4738 5870 377 -190 121 C ATOM 802 ND1 HIS A 573 29.962 47.129 17.960 1.00 40.27 N ANISOU 802 ND1 HIS A 573 4681 4648 5973 312 -86 171 N ATOM 803 CD2 HIS A 573 28.407 45.625 18.255 1.00 37.63 C ANISOU 803 CD2 HIS A 573 4379 4260 5659 397 -234 167 C ATOM 804 CE1 HIS A 573 28.816 47.774 18.113 1.00 31.75 C ANISOU 804 CE1 HIS A 573 3552 3390 5120 307 -67 255 C ATOM 805 NE2 HIS A 573 27.858 46.886 18.298 1.00 34.56 N ANISOU 805 NE2 HIS A 573 3930 3730 5471 357 -166 249 N ATOM 806 N SER A 574 32.928 43.003 15.589 1.00 38.50 N ANISOU 806 N SER A 574 3429 3887 7311 -205 654 -1442 N ATOM 807 CA SER A 574 33.947 41.952 15.534 1.00 49.04 C ANISOU 807 CA SER A 574 4622 5069 8943 -134 513 -1467 C ATOM 808 C SER A 574 34.285 41.406 16.905 1.00 48.04 C ANISOU 808 C SER A 574 4298 4777 9179 -85 247 -1548 C ATOM 809 O SER A 574 35.446 41.369 17.291 1.00 44.62 O ANISOU 809 O SER A 574 3706 4280 8966 -79 80 -1680 O ATOM 810 CB SER A 574 35.218 42.456 14.869 1.00 40.83 C ANISOU 810 CB SER A 574 3523 4019 7973 -154 616 -1565 C ATOM 811 OG SER A 574 34.930 42.886 13.555 1.00 50.63 O ANISOU 811 OG SER A 574 4877 5390 8970 -241 810 -1443 O ATOM 812 N GLN A 575 33.245 41.007 17.633 1.00 31.57 N ANISOU 812 N GLN A 575 2298 2729 6968 -162 137 -1381 N ATOM 813 CA GLN A 575 33.378 40.441 18.971 1.00 34.45 C ANISOU 813 CA GLN A 575 2538 3046 7503 -228 -205 -1279 C ATOM 814 C GLN A 575 32.423 39.266 19.152 1.00 36.35 C ANISOU 814 C GLN A 575 2837 3101 7875 -265 -161 -1066 C ATOM 815 O GLN A 575 31.433 39.140 18.426 1.00 35.10 O ANISOU 815 O GLN A 575 2837 3002 7497 -271 124 -1066 O ATOM 816 CB GLN A 575 33.098 41.505 20.034 1.00 33.44 C ANISOU 816 CB GLN A 575 2465 3148 7093 -355 -347 -1334 C ATOM 817 CG GLN A 575 34.286 42.277 20.478 1.00 33.09 C ANISOU 817 CG GLN A 575 2238 3273 7061 -338 -504 -1574 C ATOM 818 CD GLN A 575 33.886 43.623 21.035 1.00 41.25 C ANISOU 818 CD GLN A 575 3410 4512 7751 -485 -413 -1693 C ATOM 819 OE1 GLN A 575 33.852 43.845 22.254 1.00 39.03 O ANISOU 819 OE1 GLN A 575 3042 4467 7319 -524 -718 -1746 O ATOM 820 NE2 GLN A 575 33.544 44.533 20.134 1.00 48.70 N ANISOU 820 NE2 GLN A 575 4552 5395 8558 -518 -4 -1735 N ATOM 821 N ASP A 576 32.725 38.423 20.139 1.00 36.53 N ANISOU 821 N ASP A 576 2913 3051 7917 -93 -374 -799 N ATOM 822 CA ASP A 576 32.034 37.160 20.388 1.00 35.67 C ANISOU 822 CA ASP A 576 3022 2679 7854 -27 -193 -511 C ATOM 823 C ASP A 576 31.369 37.222 21.746 1.00 37.43 C ANISOU 823 C ASP A 576 3591 3005 7627 38 -261 -225 C ATOM 824 O ASP A 576 32.039 37.319 22.762 1.00 48.32 O ANISOU 824 O ASP A 576 5026 4551 8782 293 -583 -55 O ATOM 825 CB ASP A 576 33.034 35.995 20.338 1.00 39.22 C ANISOU 825 CB ASP A 576 3362 2873 8665 245 -274 -352 C ATOM 826 CG ASP A 576 32.368 34.616 20.308 1.00 41.26 C ANISOU 826 CG ASP A 576 3844 2719 9116 270 93 -113 C ATOM 827 OD1 ASP A 576 33.058 33.647 19.923 1.00 57.98 O ANISOU 827 OD1 ASP A 576 5857 4551 11622 441 154 -42 O ATOM 828 OD2 ASP A 576 31.176 34.469 20.652 1.00 52.32 O ANISOU 828 OD2 ASP A 576 5510 4044 10326 104 374 -34 O ATOM 829 N PRO A 577 30.036 37.175 21.766 1.00 41.14 N ANISOU 829 N PRO A 577 4271 3420 7942 -175 46 -220 N ATOM 830 CA PRO A 577 29.196 37.186 22.971 1.00 37.57 C ANISOU 830 CA PRO A 577 4183 3011 7082 -177 100 27 C ATOM 831 C PRO A 577 29.341 35.922 23.806 1.00 42.62 C ANISOU 831 C PRO A 577 5136 3326 7730 89 213 455 C ATOM 832 O PRO A 577 29.158 35.946 25.020 1.00 48.97 O ANISOU 832 O PRO A 577 6274 4201 8130 256 137 753 O ATOM 833 CB PRO A 577 27.780 37.258 22.416 1.00 35.04 C ANISOU 833 CB PRO A 577 3890 2665 6760 -496 486 -209 C ATOM 834 CG PRO A 577 27.917 37.581 20.988 1.00 42.16 C ANISOU 834 CG PRO A 577 4449 3641 7929 -593 535 -579 C ATOM 835 CD PRO A 577 29.243 37.144 20.529 1.00 38.26 C ANISOU 835 CD PRO A 577 3755 2999 7782 -417 370 -534 C ATOM 836 N SER A 578 29.625 34.809 23.152 1.00 48.73 N ANISOU 836 N SER A 578 5846 3721 8948 152 451 497 N ATOM 837 CA SER A 578 29.678 33.526 23.851 1.00 56.34 C ANISOU 837 CA SER A 578 7188 4257 9962 431 712 933 C ATOM 838 C SER A 578 30.571 33.575 25.094 1.00 76.16 C ANISOU 838 C SER A 578 9928 6956 12054 959 292 1339 C ATOM 839 O SER A 578 31.602 34.264 25.112 1.00 73.47 O ANISOU 839 O SER A 578 9276 7013 11625 1147 -234 1199 O ATOM 840 CB SER A 578 30.153 32.444 22.904 1.00 50.94 C ANISOU 840 CB SER A 578 6333 3165 9858 470 964 883 C ATOM 841 OG SER A 578 31.382 32.828 22.349 1.00 77.19 O ANISOU 841 OG SER A 578 9268 6717 13342 637 520 731 O ATOM 842 N GLY A 579 30.137 32.865 26.136 1.00 90.43 N ANISOU 842 N GLY A 579 12277 8498 13583 1206 565 1794 N ATOM 843 CA GLY A 579 30.769 32.918 27.445 1.00 97.54 C ANISOU 843 CA GLY A 579 13481 9653 13929 1784 194 2199 C ATOM 844 C GLY A 579 30.343 34.141 28.243 1.00 98.08 C ANISOU 844 C GLY A 579 13579 10241 13446 1647 -108 2084 C ATOM 845 O GLY A 579 29.525 34.947 27.780 1.00 85.16 O ANISOU 845 O GLY A 579 11763 8722 11872 1112 2 1726 O ATOM 846 N ASP A 580 30.897 34.282 29.446 1.00107.17 N ANISOU 846 N ASP A 580 14953 11737 14030 2174 -490 2368 N ATOM 847 CA ASP A 580 30.670 35.478 30.258 1.00107.22 C ANISOU 847 CA ASP A 580 14928 12304 13504 2081 -835 2205 C ATOM 848 C ASP A 580 31.398 36.647 29.593 1.00 96.96 C ANISOU 848 C ASP A 580 12958 11479 12402 1831 -1301 1620 C ATOM 849 O ASP A 580 32.524 36.992 29.964 1.00 96.21 O ANISOU 849 O ASP A 580 12565 11848 12143 2192 -1828 1465 O ATOM 850 CB ASP A 580 31.157 35.258 31.700 1.00114.62 C ANISOU 850 CB ASP A 580 16246 13556 13749 2788 -1143 2614 C ATOM 851 CG ASP A 580 30.921 36.466 32.611 1.00111.21 C ANISOU 851 CG ASP A 580 15774 13736 12745 2692 -1488 2408 C ATOM 852 OD1 ASP A 580 30.679 37.587 32.117 1.00102.35 O ANISOU 852 OD1 ASP A 580 14244 12850 11795 2140 -1589 1910 O ATOM 853 OD2 ASP A 580 30.980 36.283 33.848 1.00117.19 O ANISOU 853 OD2 ASP A 580 16944 14732 12850 3214 -1627 2759 O ATOM 854 N SER A 581 30.747 37.244 28.602 1.00 80.98 N ANISOU 854 N SER A 581 10702 9339 10727 1239 -1060 1264 N ATOM 855 CA SER A 581 31.364 38.302 27.816 1.00 65.68 C ANISOU 855 CA SER A 581 8223 7695 9036 984 -1317 745 C ATOM 856 C SER A 581 30.907 39.667 28.285 1.00 61.58 C ANISOU 856 C SER A 581 7659 7560 8179 700 -1424 476 C ATOM 857 O SER A 581 31.649 40.641 28.185 1.00 70.35 O ANISOU 857 O SER A 581 8393 9012 9324 625 -1696 77 O ATOM 858 CB SER A 581 31.024 38.132 26.340 1.00 58.00 C ANISOU 858 CB SER A 581 7051 6370 8616 618 -968 531 C ATOM 859 OG SER A 581 29.634 38.349 26.121 1.00 67.76 O ANISOU 859 OG SER A 581 8487 7468 9792 244 -579 494 O ATOM 860 N LYS A 582 29.677 39.715 28.793 1.00 56.45 N ANISOU 860 N LYS A 582 7391 6817 7241 522 -1147 660 N ATOM 861 CA LYS A 582 28.978 40.959 29.080 1.00 45.01 C ANISOU 861 CA LYS A 582 5940 5634 5529 193 -1128 414 C ATOM 862 C LYS A 582 28.936 41.839 27.854 1.00 39.94 C ANISOU 862 C LYS A 582 4960 4974 5243 -156 -1005 -5 C ATOM 863 O LYS A 582 29.149 43.037 27.962 1.00 52.11 O ANISOU 863 O LYS A 582 6328 6792 6681 -304 -1119 -314 O ATOM 864 CB LYS A 582 29.638 41.716 30.234 1.00 55.43 C ANISOU 864 CB LYS A 582 7186 7472 6402 391 -1559 307 C ATOM 865 CG LYS A 582 29.829 40.877 31.499 1.00 68.78 C ANISOU 865 CG LYS A 582 9238 9275 7618 896 -1740 744 C ATOM 866 CD LYS A 582 30.875 41.489 32.420 1.00 73.78 C ANISOU 866 CD LYS A 582 9614 10547 7872 1223 -2293 508 C ATOM 867 CE LYS A 582 31.080 40.648 33.677 1.00 79.96 C ANISOU 867 CE LYS A 582 10801 11513 8067 1871 -2498 974 C ATOM 868 NZ LYS A 582 29.801 40.410 34.403 1.00 81.97 N ANISOU 868 NZ LYS A 582 11676 11536 7931 1785 -2116 1387 N ATOM 869 N LEU A 583 28.658 41.257 26.691 1.00 37.53 N ANISOU 869 N LEU A 583 4583 4338 5341 -263 -728 -29 N ATOM 870 CA LEU A 583 28.501 42.049 25.469 1.00 33.26 C ANISOU 870 CA LEU A 583 3807 3781 5051 -505 -558 -379 C ATOM 871 C LEU A 583 26.999 42.316 25.184 1.00 44.88 C ANISOU 871 C LEU A 583 5452 5219 6384 -731 -224 -441 C ATOM 872 O LEU A 583 26.647 43.183 24.365 1.00 27.89 O ANISOU 872 O LEU A 583 3196 3141 4259 -848 -81 -702 O ATOM 873 CB LEU A 583 29.162 41.354 24.274 1.00 32.66 C ANISOU 873 CB LEU A 583 3490 3462 5458 -442 -489 -453 C ATOM 874 CG LEU A 583 30.701 41.178 24.314 1.00 44.42 C ANISOU 874 CG LEU A 583 4706 5005 7166 -226 -802 -509 C ATOM 875 CD1 LEU A 583 31.271 40.559 23.029 1.00 34.34 C ANISOU 875 CD1 LEU A 583 3189 3466 6390 -210 -679 -617 C ATOM 876 CD2 LEU A 583 31.393 42.483 24.602 1.00 44.43 C ANISOU 876 CD2 LEU A 583 4499 5315 7069 -306 -984 -839 C ATOM 877 N TYR A 584 26.117 41.592 25.867 1.00 32.93 N ANISOU 877 N TYR A 584 3444 2884 6182 1037 -592 -172 N ATOM 878 CA TYR A 584 24.672 41.829 25.719 1.00 35.32 C ANISOU 878 CA TYR A 584 3969 3059 6394 974 -500 -186 C ATOM 879 C TYR A 584 23.948 41.667 27.021 1.00 28.95 C ANISOU 879 C TYR A 584 3318 2260 5422 949 -609 -215 C ATOM 880 O TYR A 584 24.439 41.040 27.962 1.00 30.26 O ANISOU 880 O TYR A 584 3488 2513 5497 1040 -745 -194 O ATOM 881 CB TYR A 584 24.034 40.886 24.706 1.00 36.81 C ANISOU 881 CB TYR A 584 4292 3180 6513 1092 -386 -121 C ATOM 882 CG TYR A 584 23.927 39.429 25.152 1.00 33.30 C ANISOU 882 CG TYR A 584 3968 2751 5934 1197 -457 -54 C ATOM 883 CD1 TYR A 584 25.023 38.571 25.102 1.00 30.18 C ANISOU 883 CD1 TYR A 584 3491 2434 5542 1350 -529 -1 C ATOM 884 CD2 TYR A 584 22.706 38.892 25.561 1.00 28.70 C ANISOU 884 CD2 TYR A 584 3573 2098 5236 1145 -429 -32 C ATOM 885 CE1 TYR A 584 24.889 37.203 25.488 1.00 31.68 C ANISOU 885 CE1 TYR A 584 3825 2603 5608 1449 -574 73 C ATOM 886 CE2 TYR A 584 22.573 37.557 25.933 1.00 28.21 C ANISOU 886 CE2 TYR A 584 3616 1995 5107 1226 -458 56 C ATOM 887 CZ TYR A 584 23.650 36.720 25.892 1.00 30.60 C ANISOU 887 CZ TYR A 584 3875 2350 5400 1376 -529 109 C ATOM 888 OH TYR A 584 23.484 35.391 26.278 1.00 30.55 O ANISOU 888 OH TYR A 584 3998 2273 5336 1456 -543 207 O ATOM 889 N ARG A 585 22.772 42.255 27.061 1.00 27.96 N ANISOU 889 N ARG A 585 3326 2059 5239 858 -536 -256 N ATOM 890 CA ARG A 585 21.880 42.112 28.195 1.00 42.56 C ANISOU 890 CA ARG A 585 5331 3926 6913 858 -580 -252 C ATOM 891 C ARG A 585 20.640 41.388 27.712 1.00 36.53 C ANISOU 891 C ARG A 585 4702 3043 6136 872 -448 -184 C ATOM 892 O ARG A 585 20.090 41.744 26.651 1.00 39.12 O ANISOU 892 O ARG A 585 5036 3316 6512 824 -338 -230 O ATOM 893 CB ARG A 585 21.516 43.487 28.776 1.00 45.76 C ANISOU 893 CB ARG A 585 5757 4364 7267 753 -626 -383 C ATOM 894 CG ARG A 585 20.576 43.472 29.976 1.00 54.99 C ANISOU 894 CG ARG A 585 7086 5593 8212 800 -654 -377 C ATOM 895 CD ARG A 585 20.662 44.795 30.768 1.00 47.06 C ANISOU 895 CD ARG A 585 6086 4660 7136 767 -795 -547 C ATOM 896 NE ARG A 585 20.579 45.961 29.896 1.00 65.50 N ANISOU 896 NE ARG A 585 8369 6887 9631 623 -748 -656 N ATOM 897 CZ ARG A 585 20.504 47.219 30.333 1.00 76.90 C ANISOU 897 CZ ARG A 585 9833 8321 11066 569 -856 -817 C ATOM 898 NH1 ARG A 585 20.522 47.466 31.640 1.00 83.60 N ANISOU 898 NH1 ARG A 585 10745 9287 11733 672 -1043 -917 N ATOM 899 NH2 ARG A 585 20.408 48.228 29.467 1.00 59.85 N ANISOU 899 NH2 ARG A 585 7651 6025 9066 445 -783 -881 N ATOM 900 N LEU A 586 20.196 40.394 28.480 1.00 27.19 N ANISOU 900 N LEU A 586 3621 1846 4866 936 -449 -71 N ATOM 901 CA LEU A 586 18.899 39.795 28.246 1.00 26.86 C ANISOU 901 CA LEU A 586 3670 1673 4863 908 -330 -13 C ATOM 902 C LEU A 586 17.892 40.410 29.207 1.00 30.89 C ANISOU 902 C LEU A 586 4257 2251 5229 852 -273 -10 C ATOM 903 O LEU A 586 17.891 40.118 30.405 1.00 35.29 O ANISOU 903 O LEU A 586 4885 2892 5631 922 -284 100 O ATOM 904 CB LEU A 586 18.955 38.256 28.396 1.00 36.69 C ANISOU 904 CB LEU A 586 4971 2813 6158 994 -326 143 C ATOM 905 CG LEU A 586 17.575 37.606 28.270 1.00 37.86 C ANISOU 905 CG LEU A 586 5180 2866 6337 903 -195 198 C ATOM 906 CD1 LEU A 586 16.918 38.127 27.008 1.00 26.26 C ANISOU 906 CD1 LEU A 586 3668 1475 4835 798 -146 31 C ATOM 907 CD2 LEU A 586 17.640 36.019 28.269 1.00 39.44 C ANISOU 907 CD2 LEU A 586 5445 2958 6584 946 -189 331 C ATOM 908 N HIS A 587 17.058 41.306 28.693 1.00 35.66 N ANISOU 908 N HIS A 587 4858 2840 5853 769 -211 -130 N ATOM 909 CA HIS A 587 15.972 41.865 29.497 1.00 36.92 C ANISOU 909 CA HIS A 587 5083 3073 5871 742 -143 -136 C ATOM 910 C HIS A 587 14.921 40.833 29.894 1.00 27.83 C ANISOU 910 C HIS A 587 3959 1856 4761 739 -6 26 C ATOM 911 O HIS A 587 14.638 39.884 29.137 1.00 27.14 O ANISOU 911 O HIS A 587 3829 1599 4885 709 34 64 O ATOM 912 CB HIS A 587 15.295 43.009 28.748 1.00 30.96 C ANISOU 912 CB HIS A 587 4324 2306 5134 679 -111 -310 C ATOM 913 CG HIS A 587 16.192 44.186 28.514 1.00 40.37 C ANISOU 913 CG HIS A 587 5496 3534 6309 658 -210 -439 C ATOM 914 ND1 HIS A 587 16.507 45.093 29.504 1.00 43.61 N ANISOU 914 ND1 HIS A 587 5941 4053 6575 668 -316 -508 N ATOM 915 CD2 HIS A 587 16.844 44.600 27.401 1.00 23.35 C ANISOU 915 CD2 HIS A 587 3281 1341 4249 622 -202 -488 C ATOM 916 CE1 HIS A 587 17.297 46.031 29.005 1.00 37.54 C ANISOU 916 CE1 HIS A 587 5118 3241 5904 610 -388 -618 C ATOM 917 NE2 HIS A 587 17.530 45.744 27.736 1.00 33.16 N ANISOU 917 NE2 HIS A 587 4503 2582 5514 589 -300 -589 N ATOM 918 N PRO A 588 14.331 41.013 31.087 1.00 35.50 N ANISOU 918 N PRO A 588 4993 2952 5543 784 67 123 N ATOM 919 CA PRO A 588 13.159 40.216 31.470 1.00 29.62 C ANISOU 919 CA PRO A 588 4237 2148 4867 757 257 302 C ATOM 920 C PRO A 588 12.119 40.260 30.362 1.00 38.33 C ANISOU 920 C PRO A 588 5236 3121 6207 633 318 173 C ATOM 921 O PRO A 588 12.057 41.249 29.618 1.00 40.42 O ANISOU 921 O PRO A 588 5488 3420 6452 615 246 -46 O ATOM 922 CB PRO A 588 12.631 40.930 32.719 1.00 38.21 C ANISOU 922 CB PRO A 588 5401 3458 5661 857 329 356 C ATOM 923 CG PRO A 588 13.809 41.728 33.250 1.00 36.11 C ANISOU 923 CG PRO A 588 5215 3341 5165 977 123 237 C ATOM 924 CD PRO A 588 14.603 42.113 32.038 1.00 30.26 C ANISOU 924 CD PRO A 588 4398 2490 4610 871 -20 42 C ATOM 925 N CYS A 589 11.300 39.224 30.253 1.00 37.89 N ANISOU 925 N CYS A 589 5104 2908 6386 561 442 299 N ATOM 926 CA CYS A 589 10.204 39.217 29.295 1.00 29.28 C ANISOU 926 CA CYS A 589 3884 1701 5540 465 472 144 C ATOM 927 C CYS A 589 9.040 39.996 29.872 1.00 33.25 C ANISOU 927 C CYS A 589 4340 2373 5923 451 608 131 C ATOM 928 O CYS A 589 8.504 39.628 30.932 1.00 35.84 O ANISOU 928 O CYS A 589 4649 2766 6203 452 789 366 O ATOM 929 CB CYS A 589 9.783 37.786 28.974 1.00 32.60 C ANISOU 929 CB CYS A 589 4207 1853 6327 379 519 256 C ATOM 930 SG CYS A 589 8.321 37.729 27.942 1.00 38.06 S ANISOU 930 SG CYS A 589 4692 2511 7258 262 502 28 S ATOM 931 N ARG A 590 8.644 41.086 29.209 1.00 39.15 N ANISOU 931 N ARG A 590 5078 3203 6595 469 540 -122 N ATOM 932 CA ARG A 590 7.557 41.927 29.752 1.00 28.78 C ANISOU 932 CA ARG A 590 3731 2077 5126 494 650 -163 C ATOM 933 C ARG A 590 6.285 41.931 28.924 1.00 30.83 C ANISOU 933 C ARG A 590 3822 2280 5614 438 683 -336 C ATOM 934 O ARG A 590 5.232 42.382 29.401 1.00 30.04 O ANISOU 934 O ARG A 590 3641 2331 5442 453 806 -340 O ATOM 935 CB ARG A 590 8.035 43.372 29.899 1.00 32.73 C ANISOU 935 CB ARG A 590 4383 2750 5304 598 539 -323 C ATOM 936 CG ARG A 590 8.267 44.104 28.573 1.00 31.17 C ANISOU 936 CG ARG A 590 4216 2470 5155 609 400 -587 C ATOM 937 CD ARG A 590 8.914 45.436 28.857 1.00 38.10 C ANISOU 937 CD ARG A 590 5246 3458 5772 681 300 -691 C ATOM 938 NE ARG A 590 9.211 46.207 27.656 1.00 28.27 N ANISOU 938 NE ARG A 590 4064 2202 4476 675 207 -823 N ATOM 939 CZ ARG A 590 9.809 47.399 27.695 1.00 32.01 C ANISOU 939 CZ ARG A 590 4649 2734 4780 676 156 -869 C ATOM 940 NH1 ARG A 590 10.160 47.928 28.862 1.00 23.06 N ANISOU 940 NH1 ARG A 590 3584 1608 3571 755 77 -940 N ATOM 941 NH2 ARG A 590 10.072 48.052 26.573 1.00 27.73 N ANISOU 941 NH2 ARG A 590 4148 2239 4147 621 172 -838 N ATOM 942 N SER A 591 6.382 41.448 27.685 1.00 28.12 N ANISOU 942 N SER A 591 3420 1737 5528 409 559 -499 N ATOM 943 CA SER A 591 5.280 41.589 26.759 1.00 33.57 C ANISOU 943 CA SER A 591 3967 2417 6372 406 511 -734 C ATOM 944 C SER A 591 4.271 40.484 26.981 1.00 35.93 C ANISOU 944 C SER A 591 4017 2553 7081 274 632 -648 C ATOM 945 O SER A 591 3.181 40.527 26.440 1.00 33.06 O ANISOU 945 O SER A 591 3470 2175 6917 260 614 -843 O ATOM 946 CB SER A 591 5.764 41.570 25.315 1.00 39.16 C ANISOU 946 CB SER A 591 4748 3263 6870 426 274 -838 C ATOM 947 OG SER A 591 6.226 40.271 24.956 1.00 30.94 O ANISOU 947 OG SER A 591 3654 2091 6010 368 211 -756 O ATOM 948 N LEU A 592 4.640 39.506 27.794 1.00 44.41 N ANISOU 948 N LEU A 592 5083 3525 8267 178 750 -341 N ATOM 949 CA LEU A 592 3.737 38.409 28.181 1.00 47.73 C ANISOU 949 CA LEU A 592 5267 3782 9085 15 914 -162 C ATOM 950 C LEU A 592 4.327 37.736 29.415 1.00 55.36 C ANISOU 950 C LEU A 592 6335 4734 9967 -12 1103 253 C ATOM 951 O LEU A 592 5.476 37.985 29.778 1.00 56.57 O ANISOU 951 O LEU A 592 6719 4973 9803 99 1040 333 O ATOM 952 CB LEU A 592 3.537 37.400 27.035 1.00 36.93 C ANISOU 952 CB LEU A 592 3751 2100 8180 -64 733 -351 C ATOM 953 CG LEU A 592 4.794 36.928 26.281 1.00 43.16 C ANISOU 953 CG LEU A 592 4720 2975 8702 19 483 -391 C ATOM 954 CD1 LEU A 592 5.451 35.772 26.983 1.00 38.16 C ANISOU 954 CD1 LEU A 592 4146 2176 8179 -47 562 -90 C ATOM 955 CD2 LEU A 592 4.505 36.540 24.830 1.00 44.93 C ANISOU 955 CD2 LEU A 592 4850 3258 8961 59 225 -665 C ATOM 956 N GLN A 593 3.543 36.891 30.062 1.00 61.09 N ANISOU 956 N GLN A 593 6879 5350 10984 -145 1339 520 N ATOM 957 CA GLN A 593 3.955 36.286 31.323 1.00 65.13 C ANISOU 957 CA GLN A 593 7502 5870 11376 -122 1573 958 C ATOM 958 C GLN A 593 4.576 34.894 31.146 1.00 60.15 C ANISOU 958 C GLN A 593 6909 4871 11076 -208 1533 1126 C ATOM 959 O GLN A 593 3.860 33.928 30.881 1.00 57.76 O ANISOU 959 O GLN A 593 6390 4297 11259 -386 1596 1183 O ATOM 960 CB GLN A 593 2.749 36.207 32.262 1.00 69.74 C ANISOU 960 CB GLN A 593 7885 6566 12048 -182 1929 1236 C ATOM 961 CG GLN A 593 3.067 35.902 33.715 1.00 75.98 C ANISOU 961 CG GLN A 593 8831 7481 12555 -55 2219 1705 C ATOM 962 CD GLN A 593 1.924 36.311 34.635 1.00 85.46 C ANISOU 962 CD GLN A 593 9874 8947 13649 -9 2564 1924 C ATOM 963 OE1 GLN A 593 1.286 37.341 34.417 1.00 78.38 O ANISOU 963 OE1 GLN A 593 8887 8298 12598 42 2517 1671 O ATOM 964 NE2 GLN A 593 1.649 35.497 35.653 1.00 90.93 N ANISOU 964 NE2 GLN A 593 10537 9592 14421 -2 2930 2410 N ATOM 965 N ILE A 594 5.903 34.814 31.282 1.00 56.33 N ANISOU 965 N ILE A 594 6686 4404 10314 -69 1399 1172 N ATOM 966 CA ILE A 594 6.648 33.536 31.368 1.00 53.97 C ANISOU 966 CA ILE A 594 6483 3886 10137 -75 1353 1351 C ATOM 967 C ILE A 594 7.466 33.477 32.651 1.00 56.51 C ANISOU 967 C ILE A 594 7051 4299 10122 102 1520 1724 C ATOM 968 O ILE A 594 7.635 34.488 33.332 1.00 71.50 O ANISOU 968 O ILE A 594 9051 6544 11572 256 1557 1722 O ATOM 969 CB ILE A 594 7.639 33.333 30.193 1.00 56.83 C ANISOU 969 CB ILE A 594 6931 4255 10409 -20 979 1014 C ATOM 970 CG1 ILE A 594 8.689 34.447 30.172 1.00 50.93 C ANISOU 970 CG1 ILE A 594 6371 3700 9281 150 856 896 C ATOM 971 CG2 ILE A 594 6.912 33.311 28.884 1.00 63.77 C ANISOU 971 CG2 ILE A 594 7613 5105 11512 -109 790 657 C ATOM 972 CD1 ILE A 594 10.031 34.088 29.473 1.00 37.21 C ANISOU 972 CD1 ILE A 594 4766 2010 7362 245 586 743 C ATOM 973 N ARG A 595 8.006 32.307 32.964 1.00 54.65 N ANISOU 973 N ARG A 595 6905 3955 9906 122 1511 1903 N ATOM 974 CA ARG A 595 8.875 32.168 34.126 1.00 62.61 C ANISOU 974 CA ARG A 595 8166 5069 10552 347 1620 2219 C ATOM 975 C ARG A 595 10.048 33.169 34.115 1.00 69.01 C ANISOU 975 C ARG A 595 9162 6100 10957 558 1401 2039 C ATOM 976 O ARG A 595 10.547 33.560 33.051 1.00 68.09 O ANISOU 976 O ARG A 595 9011 5967 10895 517 1132 1697 O ATOM 977 CB ARG A 595 9.412 30.747 34.202 1.00 63.64 C ANISOU 977 CB ARG A 595 8380 5023 10779 341 1561 2338 C ATOM 978 CG ARG A 595 10.117 30.430 35.505 1.00 73.89 C ANISOU 978 CG ARG A 595 9926 6430 11720 592 1708 2690 C ATOM 979 CD ARG A 595 10.511 28.973 35.554 1.00 80.20 C ANISOU 979 CD ARG A 595 10806 7007 12659 572 1669 2811 C ATOM 980 NE ARG A 595 11.318 28.604 34.398 1.00 74.48 N ANISOU 980 NE ARG A 595 10102 6161 12037 525 1312 2483 N ATOM 981 CZ ARG A 595 11.581 27.349 34.051 1.00 72.90 C ANISOU 981 CZ ARG A 595 9952 5725 12020 475 1207 2484 C ATOM 982 NH1 ARG A 595 11.081 26.350 34.767 1.00 63.65 N ANISOU 982 NH1 ARG A 595 8804 4381 10998 433 1431 2797 N ATOM 983 NH2 ARG A 595 12.334 27.097 32.983 1.00 64.40 N ANISOU 983 NH2 ARG A 595 8914 4591 10964 485 891 2179 N ATOM 984 N GLN A 596 10.471 33.589 35.305 1.00 69.37 N ANISOU 984 N GLN A 596 9380 6430 10548 794 1484 2213 N ATOM 985 CA GLN A 596 11.602 34.500 35.443 1.00 66.77 C ANISOU 985 CA GLN A 596 9185 6374 9810 985 1227 1986 C ATOM 986 C GLN A 596 12.236 34.371 36.826 1.00 66.16 C ANISOU 986 C GLN A 596 9331 6499 9309 1298 1294 2240 C ATOM 987 O GLN A 596 13.433 34.611 36.996 1.00 65.02 O ANISOU 987 O GLN A 596 9306 6485 8914 1478 1056 2109 O ATOM 988 CB GLN A 596 11.159 35.945 35.176 1.00 63.57 C ANISOU 988 CB GLN A 596 8691 6212 9252 943 1147 1685 C ATOM 989 CG GLN A 596 9.863 36.357 35.874 1.00 67.05 C ANISOU 989 CG GLN A 596 9061 6805 9611 946 1419 1831 C ATOM 990 CD GLN A 596 9.482 37.812 35.592 1.00 78.73 C ANISOU 990 CD GLN A 596 10486 8515 10915 939 1305 1509 C ATOM 991 OE1 GLN A 596 9.958 38.414 34.628 1.00 73.74 O ANISOU 991 OE1 GLN A 596 9825 7850 10344 858 1063 1188 O ATOM 992 NE2 GLN A 596 8.619 38.378 36.435 1.00 81.68 N ANISOU 992 NE2 GLN A 596 10854 9121 11058 1050 1496 1612 N TER 993 GLN A 596 ATOM 994 O5'A DT D 1 26.843 33.218 2.954 0.51 76.30 O ANISOU 994 O5'A DT D 1 10693 12171 6125 883 2122 1137 O ATOM 995 O5'B DT D 1 33.033 31.909 3.374 0.49 77.41 O ANISOU 995 O5'B DT D 1 9433 14370 5608 785 2407 1658 O ATOM 996 C5'A DT D 1 27.029 34.367 2.136 0.51 79.09 C ANISOU 996 C5'A DT D 1 11011 12721 6319 644 2132 1550 C ATOM 997 C5'B DT D 1 32.223 31.612 2.247 0.49 76.70 C ANISOU 997 C5'B DT D 1 9504 14287 5351 1147 2370 1476 C ATOM 998 C4'A DT D 1 25.696 35.011 1.798 0.51 80.40 C ANISOU 998 C4'A DT D 1 11412 12370 6767 610 1999 1600 C ATOM 999 C4'B DT D 1 31.135 32.656 2.080 0.49 76.01 C ANISOU 999 C4'B DT D 1 9678 13879 5321 874 2343 1609 C ATOM 1000 O4'A DT D 1 25.011 34.214 0.796 0.51 81.38 O ANISOU 1000 O4'A DT D 1 11573 12603 6744 987 1863 1419 O ATOM 1001 O4'B DT D 1 30.119 32.142 1.186 0.49 74.38 O ANISOU 1001 O4'B DT D 1 9691 13582 4988 1263 2268 1352 O ATOM 1002 C3'A DT D 1 24.722 35.111 2.960 0.51 75.76 C ANISOU 1002 C3'A DT D 1 11038 11067 6680 560 1975 1424 C ATOM 1003 C3'B DT D 1 30.423 33.039 3.371 0.49 73.03 C ANISOU 1003 C3'B DT D 1 9551 12974 5224 578 2362 1548 C ATOM 1004 O3'A DT D 1 24.933 36.319 3.665 0.51 73.94 O ANISOU 1004 O3'A DT D 1 10957 10524 6613 182 2031 1665 O ATOM 1005 O3'B DT D 1 31.003 34.239 3.894 0.49 76.68 O ANISOU 1005 O3'B DT D 1 9973 13395 5768 24 2362 1971 O ATOM 1006 C2'A DT D 1 23.375 35.106 2.250 0.51 74.63 C ANISOU 1006 C2'A DT D 1 11003 10651 6703 756 1823 1419 C ATOM 1007 C2'B DT D 1 28.975 33.268 2.936 0.49 69.86 C ANISOU 1007 C2'B DT D 1 9455 12248 4839 726 2329 1462 C ATOM 1008 C1'A DT D 1 23.631 34.124 1.112 0.51 77.03 C ANISOU 1008 C1'A DT D 1 11202 11456 6609 1054 1720 1289 C ATOM 1009 C1'B DT D 1 28.829 32.376 1.704 0.49 70.11 C ANISOU 1009 C1'B DT D 1 9461 12548 4630 1200 2237 1237 C ATOM 1010 N1 A DT D 1 23.311 32.703 1.457 0.51 72.71 N ANISOU 1010 N1 A DT D 1 10685 10826 6115 1360 1603 896 N ATOM 1011 N1 B DT D 1 28.166 31.051 1.964 0.49 68.70 N ANISOU 1011 N1 B DT D 1 9466 12115 4523 1613 2128 753 N ATOM 1012 C2 A DT D 1 21.998 32.290 1.464 0.51 71.97 C ANISOU 1012 C2 A DT D 1 10704 10316 6326 1479 1388 807 C ATOM 1013 C2 B DT D 1 26.804 30.946 1.826 0.49 71.81 C ANISOU 1013 C2 B DT D 1 10143 12064 5077 1725 1976 599 C ATOM 1014 O2 A DT D 1 21.062 33.027 1.208 0.51 75.07 O ANISOU 1014 O2 A DT D 1 11146 10423 6956 1388 1323 1034 O ATOM 1015 O2 B DT D 1 26.092 31.886 1.516 0.49 76.44 O ANISOU 1015 O2 B DT D 1 10814 12392 5838 1502 1922 815 O ATOM 1016 N3 A DT D 1 21.818 30.973 1.787 0.51 70.00 N ANISOU 1016 N3 A DT D 1 10495 10002 6101 1703 1225 486 N ATOM 1017 N3 B DT D 1 26.295 29.697 2.072 0.49 69.70 N ANISOU 1017 N3 B DT D 1 10033 11558 4892 2040 1800 198 N ATOM 1018 C4 A DT D 1 22.798 30.046 2.095 0.51 68.94 C ANISOU 1018 C4 A DT D 1 10328 10148 5718 1865 1275 214 C ATOM 1019 C4 B DT D 1 27.002 28.563 2.428 0.49 68.35 C ANISOU 1019 C4 B DT D 1 9796 11528 4646 2275 1772 -76 C ATOM 1020 O4 A DT D 1 22.538 28.881 2.373 0.51 69.60 O ANISOU 1020 O4 A DT D 1 10497 10100 5848 2059 1074 -64 O ATOM 1021 O4 B DT D 1 26.454 27.483 2.624 0.49 71.32 O ANISOU 1021 O4 B DT D 1 10363 11628 5109 2519 1552 -404 O ATOM 1022 C5 A DT D 1 24.147 30.543 2.068 0.51 67.84 C ANISOU 1022 C5 A DT D 1 10036 10473 5269 1779 1548 327 C ATOM 1023 C5 B DT D 1 28.429 28.739 2.548 0.49 67.72 C ANISOU 1023 C5 B DT D 1 9389 11842 4500 2137 1933 99 C ATOM 1024 C7 A DT D 1 25.292 29.627 2.386 0.51 70.04 C ANISOU 1024 C7 A DT D 1 10216 11127 5269 1981 1644 107 C ATOM 1025 C7 B DT D 1 29.303 27.580 2.930 0.49 66.82 C ANISOU 1025 C7 B DT D 1 9153 11823 4414 2347 1882 -113 C ATOM 1026 C6 A DT D 1 24.337 31.830 1.752 0.51 68.20 C ANISOU 1026 C6 A DT D 1 10017 10607 5290 1509 1685 678 C ATOM 1027 C6 B DT D 1 28.936 29.959 2.310 0.49 68.79 C ANISOU 1027 C6 B DT D 1 9348 12239 4551 1816 2096 502 C ATOM 1028 P A DG D 2 25.190 36.285 5.249 0.45 96.20 P ANISOU 1028 P A DG D 2 13914 12973 9666 23 2116 1507 P ATOM 1029 P B DG D 2 31.231 34.421 5.477 0.55 90.60 P ANISOU 1029 P B DG D 2 11855 14806 7762 -341 2376 1975 P ATOM 1030 OP1A DG D 2 26.180 37.339 5.565 0.45 99.07 O ANISOU 1030 OP1A DG D 2 14359 13374 9909 -434 2111 1831 O ATOM 1031 OP1B DG D 2 32.212 35.513 5.662 0.55 91.01 O ANISOU 1031 OP1B DG D 2 11813 14934 7833 -873 2268 2445 O ATOM 1032 OP2A DG D 2 25.465 34.878 5.621 0.45 88.51 O ANISOU 1032 OP2A DG D 2 12757 12226 8647 275 2148 1165 O ATOM 1033 OP2B DG D 2 31.504 33.089 6.059 0.55 89.04 O ANISOU 1033 OP2B DG D 2 11542 14673 7615 -16 2421 1588 O ATOM 1034 O5'A DG D 2 23.777 36.690 5.872 0.45 82.44 O ANISOU 1034 O5'A DG D 2 12460 10524 8339 145 2119 1423 O ATOM 1035 O5'B DG D 2 29.812 34.924 6.014 0.55 77.63 O ANISOU 1035 O5'B DG D 2 10665 12389 6443 -410 2324 1793 O ATOM 1036 C5'A DG D 2 23.065 37.797 5.339 0.45 87.01 C ANISOU 1036 C5'A DG D 2 13226 10815 9019 98 2069 1685 C ATOM 1037 C5'B DG D 2 29.259 36.133 5.517 0.55 80.02 C ANISOU 1037 C5'B DG D 2 11184 12409 6811 -641 2234 2057 C ATOM 1038 C4'A DG D 2 21.606 37.443 5.112 0.45 89.99 C ANISOU 1038 C4'A DG D 2 13592 10925 9676 448 2039 1605 C ATOM 1039 C4'B DG D 2 27.761 36.167 5.739 0.55 82.33 C ANISOU 1039 C4'B DG D 2 11813 12017 7453 -427 2196 1758 C ATOM 1040 O4'A DG D 2 21.514 36.126 4.507 0.45 91.73 O ANISOU 1040 O4'A DG D 2 13548 11518 9787 678 1941 1404 O ATOM 1041 O4'B DG D 2 27.158 35.006 5.113 0.55 83.24 O ANISOU 1041 O4'B DG D 2 11803 12300 7524 64 2206 1440 O ATOM 1042 C3'A DG D 2 20.745 37.401 6.374 0.45 87.06 C ANISOU 1042 C3'A DG D 2 13389 10033 9656 615 2158 1468 C ATOM 1043 C3'B DG D 2 27.328 36.162 7.207 0.55 83.87 C ANISOU 1043 C3'B DG D 2 12297 11585 7986 -508 2213 1521 C ATOM 1044 O3'A DG D 2 19.522 38.081 6.146 0.45 90.31 O ANISOU 1044 O3'A DG D 2 13911 10087 10314 801 2163 1666 O ATOM 1045 O3'B DG D 2 26.436 37.261 7.463 0.55 86.70 O ANISOU 1045 O3'B DG D 2 13048 11317 8578 -621 2169 1617 O ATOM 1046 C2'A DG D 2 20.525 35.909 6.619 0.45 83.14 C ANISOU 1046 C2'A DG D 2 12642 9724 9222 830 2119 1183 C ATOM 1047 C2'B DG D 2 26.655 34.797 7.407 0.55 79.30 C ANISOU 1047 C2'B DG D 2 11621 10968 7542 -66 2251 1092 C ATOM 1048 C1'A DG D 2 20.591 35.331 5.214 0.45 84.36 C ANISOU 1048 C1'A DG D 2 12588 10311 9152 909 1931 1208 C ATOM 1049 C1'B DG D 2 26.255 34.380 5.995 0.55 82.82 C ANISOU 1049 C1'B DG D 2 11909 11751 7807 248 2194 1088 C ATOM 1050 N9 A DG D 2 21.063 33.950 5.186 0.45 82.05 N ANISOU 1050 N9 A DG D 2 12130 10340 8703 1032 1841 921 N ATOM 1051 N9 B DG D 2 26.339 32.933 5.778 0.55 83.25 N ANISOU 1051 N9 B DG D 2 11795 12094 7741 624 2166 771 N ATOM 1052 C8 A DG D 2 22.352 33.514 5.378 0.45 81.98 C ANISOU 1052 C8 A DG D 2 12044 10689 8416 948 1905 776 C ATOM 1053 C8 B DG D 2 27.482 32.168 5.766 0.55 83.83 C ANISOU 1053 C8 B DG D 2 11641 12684 7528 725 2228 708 C ATOM 1054 N7 A DG D 2 22.481 32.218 5.302 0.45 80.72 N ANISOU 1054 N7 A DG D 2 11784 10726 8162 1158 1791 512 N ATOM 1055 N7 B DG D 2 27.262 30.901 5.548 0.55 81.12 N ANISOU 1055 N7 B DG D 2 11275 12432 7114 1122 2149 383 N ATOM 1056 C5 A DG D 2 21.194 31.762 5.044 0.45 80.58 C ANISOU 1056 C5 A DG D 2 11790 10451 8378 1335 1596 495 C ATOM 1057 C5 B DG D 2 25.883 30.814 5.409 0.55 77.71 C ANISOU 1057 C5 B DG D 2 11042 11531 6954 1231 1996 257 C ATOM 1058 C6 A DG D 2 20.713 30.440 4.859 0.45 77.41 C ANISOU 1058 C6 A DG D 2 11369 10049 7995 1551 1332 284 C ATOM 1059 C6 B DG D 2 25.063 29.686 5.160 0.55 72.02 C ANISOU 1059 C6 B DG D 2 10417 10649 6299 1558 1782 -31 C ATOM 1060 O6 A DG D 2 21.352 29.377 4.889 0.45 72.88 O ANISOU 1060 O6 A DG D 2 10791 9683 7217 1687 1237 17 O ATOM 1061 O6 B DG D 2 25.408 28.508 5.012 0.55 66.60 O ANISOU 1061 O6 B DG D 2 9728 10155 5422 1853 1677 -292 O ATOM 1062 N1 A DG D 2 19.339 30.422 4.619 0.45 79.76 N ANISOU 1062 N1 A DG D 2 11667 10056 8582 1605 1135 446 N ATOM 1063 N1 B DG D 2 23.716 30.031 5.090 0.55 73.30 N ANISOU 1063 N1 B DG D 2 10707 10364 6781 1519 1653 37 N ATOM 1064 C2 A DG D 2 18.534 31.540 4.564 0.45 83.25 C ANISOU 1064 C2 A DG D 2 12104 10264 9264 1530 1235 761 C ATOM 1065 C2 B DG D 2 23.224 31.306 5.240 0.55 79.38 C ANISOU 1065 C2 B DG D 2 11529 10867 7765 1277 1759 311 C ATOM 1066 N2 A DG D 2 17.230 31.324 4.322 0.45 82.62 N ANISOU 1066 N2 A DG D 2 11957 9975 9459 1609 1017 952 N ATOM 1067 N2 B DG D 2 21.894 31.444 5.140 0.55 80.12 N ANISOU 1067 N2 B DG D 2 11699 10587 8157 1335 1634 385 N ATOM 1068 N3 A DG D 2 18.973 32.782 4.737 0.45 85.61 N ANISOU 1068 N3 A DG D 2 12472 10523 9535 1384 1498 913 N ATOM 1069 N3 B DG D 2 23.982 32.375 5.474 0.55 81.19 N ANISOU 1069 N3 B DG D 2 11753 11180 7917 996 1944 531 N ATOM 1070 C4 A DG D 2 20.309 32.817 4.971 0.45 84.04 C ANISOU 1070 C4 A DG D 2 12294 10583 9056 1263 1643 769 C ATOM 1071 C4 B DG D 2 25.297 32.055 5.543 0.55 80.88 C ANISOU 1071 C4 B DG D 2 11562 11586 7580 954 2035 505 C ATOM 1072 P A DC D 3 18.663 38.646 7.381 0.49 69.47 P ANISOU 1072 P A DC D 3 11553 6867 7974 1003 2354 1673 P ATOM 1073 P B DC D 3 25.679 37.407 8.876 0.51 84.55 P ANISOU 1073 P B DC D 3 13161 10337 8629 -577 2227 1384 P ATOM 1074 OP1A DC D 3 17.837 39.749 6.848 0.49 72.45 O ANISOU 1074 OP1A DC D 3 12097 6952 8478 1124 2348 1976 O ATOM 1075 OP1B DC D 3 25.391 38.844 9.083 0.51 83.60 O ANISOU 1075 OP1B DC D 3 13495 9695 8574 -804 2161 1619 O ATOM 1076 OP2A DC D 3 19.570 38.876 8.529 0.49 66.77 O ANISOU 1076 OP2A DC D 3 11492 6355 7522 801 2457 1511 O ATOM 1077 OP2B DC D 3 26.450 36.687 9.911 0.51 84.60 O ANISOU 1077 OP2B DC D 3 13095 10439 8611 -683 2267 1205 O ATOM 1078 O5'A DC D 3 17.704 37.427 7.769 0.49 79.93 O ANISOU 1078 O5'A DC D 3 12578 8243 9549 1314 2374 1546 O ATOM 1079 O5'B DC D 3 24.295 36.640 8.630 0.51 70.18 O ANISOU 1079 O5'B DC D 3 11252 8368 7047 -91 2283 1138 O ATOM 1080 C5'A DC D 3 16.913 36.801 6.769 0.49 75.46 C ANISOU 1080 C5'A DC D 3 11704 7891 9077 1452 2184 1665 C ATOM 1081 C5'B DC D 3 23.574 36.877 7.423 0.51 72.35 C ANISOU 1081 C5'B DC D 3 11446 8722 7320 78 2219 1279 C ATOM 1082 C4'A DC D 3 16.333 35.497 7.281 0.49 67.75 C ANISOU 1082 C4'A DC D 3 10468 6989 8285 1615 2120 1533 C ATOM 1083 C4'B DC D 3 22.232 36.166 7.427 0.51 75.46 C ANISOU 1083 C4'B DC D 3 11772 8912 7987 464 2220 1108 C ATOM 1084 O4'A DC D 3 17.289 34.421 7.081 0.49 65.15 O ANISOU 1084 O4'A DC D 3 10036 7003 7716 1475 1968 1241 O ATOM 1085 O4'B DC D 3 22.416 34.756 7.133 0.51 72.94 O ANISOU 1085 O4'B DC D 3 11171 8969 7573 648 2142 871 O ATOM 1086 C3'A DC D 3 15.985 35.481 8.778 0.49 66.23 C ANISOU 1086 C3'A DC D 3 10355 6514 8296 1766 2368 1468 C ATOM 1087 C3'B DC D 3 21.461 36.231 8.741 0.51 73.85 C ANISOU 1087 C3'B DC D 3 11773 8197 8089 588 2349 993 C ATOM 1088 O3'A DC D 3 14.708 34.873 8.967 0.49 68.30 O ANISOU 1088 O3'A DC D 3 10333 6751 8868 2012 2322 1657 O ATOM 1089 O3'B DC D 3 20.072 36.418 8.461 0.51 72.88 O ANISOU 1089 O3'B DC D 3 11649 7818 8223 870 2353 1110 O ATOM 1090 C2'A DC D 3 17.097 34.615 9.371 0.49 63.98 C ANISOU 1090 C2'A DC D 3 10066 6413 7830 1580 2348 1117 C ATOM 1091 C2'B DC D 3 21.750 34.868 9.376 0.51 67.85 C ANISOU 1091 C2'B DC D 3 10807 7628 7346 672 2345 698 C ATOM 1092 C1'A DC D 3 17.291 33.629 8.238 0.49 64.28 C ANISOU 1092 C1'A DC D 3 9870 6820 7733 1527 2038 1045 C ATOM 1093 C1'B DC D 3 21.840 33.971 8.154 0.51 65.59 C ANISOU 1093 C1'B DC D 3 10233 7791 6897 805 2173 648 C ATOM 1094 N1 A DC D 3 18.556 32.823 8.311 0.49 65.97 N ANISOU 1094 N1 A DC D 3 10066 7325 7675 1380 1973 734 N ATOM 1095 N1 B DC D 3 22.701 32.766 8.347 0.51 62.08 N ANISOU 1095 N1 B DC D 3 9609 7691 6286 835 2123 395 N ATOM 1096 C2 A DC D 3 18.534 31.495 7.882 0.49 63.08 C ANISOU 1096 C2 A DC D 3 9535 7180 7251 1458 1705 570 C ATOM 1097 C2 B DC D 3 22.134 31.491 8.266 0.51 64.47 C ANISOU 1097 C2 B DC D 3 9784 8029 6681 1084 1964 189 C ATOM 1098 O2 A DC D 3 17.483 31.033 7.433 0.49 63.86 O ANISOU 1098 O2 A DC D 3 9520 7219 7526 1577 1482 704 O ATOM 1099 O2 B DC D 3 20.921 31.384 8.049 0.51 64.94 O ANISOU 1099 O2 B DC D 3 9839 7863 6971 1230 1856 263 O ATOM 1100 N3 A DC D 3 19.663 30.757 7.958 0.49 62.52 N ANISOU 1100 N3 A DC D 3 9456 7373 6925 1405 1668 297 N ATOM 1101 N3 B DC D 3 22.933 30.406 8.424 0.51 63.37 N ANISOU 1101 N3 B DC D 3 9534 8166 6376 1152 1900 -49 N ATOM 1102 C4 A DC D 3 20.781 31.291 8.446 0.49 64.11 C ANISOU 1102 C4 A DC D 3 9737 7665 6956 1234 1880 236 C ATOM 1103 C4 B DC D 3 24.238 30.566 8.652 0.51 60.57 C ANISOU 1103 C4 B DC D 3 9126 8102 5784 994 2024 -51 C ATOM 1104 N4 A DC D 3 21.870 30.512 8.498 0.49 63.54 N ANISOU 1104 N4 A DC D 3 9596 7902 6642 1218 1847 18 N ATOM 1105 N4 B DC D 3 24.985 29.467 8.805 0.51 66.85 N ANISOU 1105 N4 B DC D 3 9798 9177 6426 1122 1973 -268 N ATOM 1106 C5 A DC D 3 20.829 32.647 8.901 0.49 65.02 C ANISOU 1106 C5 A DC D 3 10033 7541 7132 1074 2102 423 C ATOM 1107 C5 B DC D 3 24.833 31.856 8.736 0.51 55.80 C ANISOU 1107 C5 B DC D 3 8601 7506 5094 688 2171 210 C ATOM 1108 C6 A DC D 3 19.701 33.370 8.819 0.49 63.84 C ANISOU 1108 C6 A DC D 3 9959 7085 7213 1178 2144 641 C ATOM 1109 C6 B DC D 3 24.035 32.917 8.575 0.51 58.89 C ANISOU 1109 C6 B DC D 3 9170 7565 5639 613 2197 408 C ATOM 1110 P A DT D 4 13.561 35.601 9.830 0.50 65.25 P ANISOU 1110 P A DT D 4 9981 6052 8760 2364 2621 1941 P ATOM 1111 P B DT D 4 18.966 36.288 9.620 0.50 78.81 P ANISOU 1111 P B DT D 4 12482 8163 9299 1148 2513 1064 P ATOM 1112 OP1A DT D 4 12.278 35.355 9.140 0.50 69.88 O ANISOU 1112 OP1A DT D 4 10204 6735 9614 2537 2457 2337 O ATOM 1113 OP1B DT D 4 17.872 37.223 9.271 0.50 78.49 O ANISOU 1113 OP1B DT D 4 12558 7828 9439 1359 2569 1342 O ATOM 1114 OP2A DT D 4 14.001 36.982 10.127 0.50 70.43 O ANISOU 1114 OP2A DT D 4 11099 6385 9274 2391 2861 1922 O ATOM 1115 OP2B DT D 4 19.638 36.429 10.935 0.50 74.19 O ANISOU 1115 OP2B DT D 4 12156 7376 8657 1015 2657 893 O ATOM 1116 O5'A DT D 4 13.543 34.797 11.205 0.50 63.48 O ANISOU 1116 O5'A DT D 4 9682 5818 8619 2443 2768 1776 O ATOM 1117 O5'B DT D 4 18.439 34.780 9.463 0.50 62.63 O ANISOU 1117 O5'B DT D 4 10047 6371 7377 1322 2373 934 O ATOM 1118 C5'A DT D 4 14.232 33.561 11.301 0.50 64.83 C ANISOU 1118 C5'A DT D 4 9706 6224 8702 2209 2551 1492 C ATOM 1119 C5'B DT D 4 17.314 34.324 10.212 0.50 64.14 C ANISOU 1119 C5'B DT D 4 10124 6374 7874 1573 2440 981 C ATOM 1120 C4'A DT D 4 13.412 32.419 10.722 0.50 64.05 C ANISOU 1120 C4'A DT D 4 9198 6339 8798 2217 2203 1671 C ATOM 1121 C4'B DT D 4 16.945 32.902 9.817 0.50 65.33 C ANISOU 1121 C4'B DT D 4 9940 6777 8103 1631 2172 909 C ATOM 1122 O4'A DT D 4 14.316 31.477 10.087 0.50 66.09 O ANISOU 1122 O4'A DT D 4 9460 6816 8838 1975 1882 1364 O ATOM 1123 O4'B DT D 4 18.161 32.128 9.620 0.50 65.88 O ANISOU 1123 O4'B DT D 4 9993 7136 7901 1462 2045 615 O ATOM 1124 C3'A DT D 4 12.680 31.598 11.767 0.50 62.72 C ANISOU 1124 C3'A DT D 4 8764 6190 8878 2336 2232 1795 C ATOM 1125 C3'B DT D 4 16.131 32.131 10.861 0.50 61.74 C ANISOU 1125 C3'B DT D 4 9314 6217 7928 1781 2203 931 C ATOM 1126 O3'A DT D 4 11.620 30.826 11.180 0.50 63.29 O ANISOU 1126 O3'A DT D 4 8452 6403 9191 2341 1878 2144 O ATOM 1127 O3'B DT D 4 15.213 31.237 10.215 0.50 62.67 O ANISOU 1127 O3'B DT D 4 9142 6453 8218 1855 1884 1096 O ATOM 1128 C2'A DT D 4 13.802 30.708 12.261 0.50 63.35 C ANISOU 1128 C2'A DT D 4 8941 6354 8775 2114 2135 1363 C ATOM 1129 C2'B DT D 4 17.216 31.367 11.604 0.50 59.59 C ANISOU 1129 C2'B DT D 4 9085 6051 7503 1623 2202 586 C ATOM 1130 C1'A DT D 4 14.555 30.388 10.965 0.50 64.94 C ANISOU 1130 C1'A DT D 4 9218 6722 8736 1922 1812 1166 C ATOM 1131 C1'B DT D 4 18.118 30.990 10.447 0.50 58.39 C ANISOU 1131 C1'B DT D 4 8920 6202 7063 1496 1975 434 C ATOM 1132 N1 A DT D 4 16.045 30.227 11.160 0.50 64.39 N ANISOU 1132 N1 A DT D 4 9364 6745 8358 1746 1867 751 N ATOM 1133 N1 B DT D 4 19.505 30.616 10.841 0.50 58.04 N ANISOU 1133 N1 B DT D 4 8940 6340 6772 1334 2016 152 N ATOM 1134 C2 A DT D 4 16.627 28.980 11.022 0.50 54.86 C ANISOU 1134 C2 A DT D 4 8095 5714 7036 1656 1583 493 C ATOM 1135 C2 B DT D 4 19.843 29.287 10.866 0.50 59.43 C ANISOU 1135 C2 B DT D 4 8987 6700 6895 1369 1803 -72 C ATOM 1136 O2 A DT D 4 16.009 27.977 10.727 0.50 48.62 O ANISOU 1136 O2 A DT D 4 7147 4961 6367 1678 1237 554 O ATOM 1137 O2 B DT D 4 19.063 28.390 10.585 0.50 56.46 O ANISOU 1137 O2 B DT D 4 8490 6305 6656 1487 1537 -59 O ATOM 1138 N3 A DT D 4 17.979 28.954 11.227 0.50 56.67 N ANISOU 1138 N3 A DT D 4 8473 6068 6992 1536 1686 189 N ATOM 1139 N3 B DT D 4 21.136 29.035 11.226 0.50 58.85 N ANISOU 1139 N3 B DT D 4 8942 6820 6598 1250 1871 -280 N ATOM 1140 C4 A DT D 4 18.795 30.016 11.559 0.50 57.51 C ANISOU 1140 C4 A DT D 4 8775 6135 6940 1425 1986 151 C ATOM 1141 C4 B DT D 4 22.116 29.946 11.561 0.50 53.14 C ANISOU 1141 C4 B DT D 4 8340 6142 5709 1042 2090 -246 C ATOM 1142 O4 A DT D 4 20.003 29.886 11.726 0.50 59.36 O ANISOU 1142 O4 A DT D 4 9076 6533 6944 1284 2027 -51 O ATOM 1143 O4 B DT D 4 23.258 29.599 11.870 0.50 54.33 O ANISOU 1143 O4 B DT D 4 8450 6517 5676 927 2114 -376 O ATOM 1144 C5 A DT D 4 18.130 31.288 11.694 0.50 59.53 C ANISOU 1144 C5 A DT D 4 9165 6138 7316 1488 2215 403 C ATOM 1145 C5 B DT D 4 21.706 31.326 11.518 0.50 51.93 C ANISOU 1145 C5 B DT D 4 8374 5745 5612 965 2251 -12 C ATOM 1146 C7 A DT D 4 18.915 32.514 12.056 0.50 62.98 C ANISOU 1146 C7 A DT D 4 9914 6432 7583 1339 2456 397 C ATOM 1147 C7 B DT D 4 22.684 32.407 11.863 0.50 45.66 C ANISOU 1147 C7 B DT D 4 7791 4915 4642 679 2397 79 C ATOM 1148 C6 A DT D 4 16.804 31.332 11.493 0.50 61.46 C ANISOU 1148 C6 A DT D 4 9263 6269 7821 1681 2171 672 C ATOM 1149 C6 B DT D 4 20.429 31.597 11.164 0.50 57.31 C ANISOU 1149 C6 B DT D 4 9046 6222 6507 1144 2226 155 C ATOM 1150 P A DT D 5 10.523 30.106 12.121 0.57 72.07 P ANISOU 1150 P A DT D 5 9163 7590 10630 2468 1871 2508 P ATOM 1151 P B DT D 5 13.807 30.874 10.910 0.43 67.80 P ANISOU 1151 P B DT D 5 9508 7005 9247 2045 1893 1427 P ATOM 1152 OP1A DT D 5 9.178 30.476 11.632 0.57 67.95 O ANISOU 1152 OP1A DT D 5 8310 7125 10383 2650 1823 3104 O ATOM 1153 OP1B DT D 5 12.739 31.197 9.934 0.43 68.14 O ANISOU 1153 OP1B DT D 5 9377 7060 9455 2140 1727 1828 O ATOM 1154 OP2A DT D 5 10.877 30.356 13.536 0.57 69.73 O ANISOU 1154 OP2A DT D 5 9009 7201 10284 2611 2306 2332 O ATOM 1155 OP2B DT D 5 13.801 31.519 12.243 0.43 61.01 O ANISOU 1155 OP2B DT D 5 8785 5953 8442 2187 2322 1416 O ATOM 1156 O5'A DT D 5 10.752 28.545 11.863 0.57 79.22 O ANISOU 1156 O5'A DT D 5 9936 8626 11539 2168 1321 2360 O ATOM 1157 O5'B DT D 5 13.859 29.279 11.120 0.43 69.83 O ANISOU 1157 O5'B DT D 5 9574 7402 9555 1922 1529 1282 O ATOM 1158 C5'A DT D 5 11.812 28.113 11.025 0.57 80.09 C ANISOU 1158 C5'A DT D 5 10319 8757 11353 1962 1037 1926 C ATOM 1159 C5'B DT D 5 12.805 28.611 11.863 0.43 77.57 C ANISOU 1159 C5'B DT D 5 10245 8373 10854 1993 1447 1574 C ATOM 1160 C4'A DT D 5 12.456 26.849 11.567 0.57 73.43 C ANISOU 1160 C4'A DT D 5 9508 7952 10441 1802 796 1602 C ATOM 1161 C4'B DT D 5 13.027 27.101 11.924 0.43 73.17 C ANISOU 1161 C4'B DT D 5 9599 7901 10299 1815 1005 1403 C ATOM 1162 O4'A DT D 5 13.881 27.057 11.790 0.57 71.12 O ANISOU 1162 O4'A DT D 5 9524 7664 9832 1759 1025 1102 O ATOM 1163 O4'B DT D 5 14.446 26.826 11.797 0.43 71.64 O ANISOU 1163 O4'B DT D 5 9685 7759 9776 1712 998 899 O ATOM 1164 C3'A DT D 5 11.926 26.362 12.910 0.57 66.36 C ANISOU 1164 C3'A DT D 5 8361 7058 9797 1830 909 1785 C ATOM 1165 C3'B DT D 5 12.586 26.429 13.231 0.43 68.61 C ANISOU 1165 C3'B DT D 5 8795 7322 9952 1817 1053 1529 C ATOM 1166 O3'A DT D 5 12.070 24.972 12.933 0.57 53.70 O ANISOU 1166 O3'A DT D 5 6712 5479 8213 1632 421 1668 O ATOM 1167 O3'B DT D 5 12.137 25.059 12.996 0.43 59.30 O ANISOU 1167 O3'B DT D 5 7435 6186 8909 1645 474 1645 O ATOM 1168 C2'A DT D 5 12.909 27.009 13.874 0.57 70.67 C ANISOU 1168 C2'A DT D 5 9159 7534 10158 1897 1411 1430 C ATOM 1169 C2'B DT D 5 13.860 26.486 14.068 0.43 70.82 C ANISOU 1169 C2'B DT D 5 9333 7568 10008 1768 1334 1064 C ATOM 1170 C1'A DT D 5 14.177 26.693 13.126 0.57 72.23 C ANISOU 1170 C1'A DT D 5 9634 7773 10037 1741 1216 971 C ATOM 1171 C1'B DT D 5 14.952 26.303 13.012 0.43 72.76 C ANISOU 1171 C1'B DT D 5 9825 7883 9937 1661 1122 694 C ATOM 1172 N1 A DT D 5 15.392 27.425 13.593 0.57 75.02 N ANISOU 1172 N1 A DT D 5 10274 8095 10136 1715 1592 632 N ATOM 1173 N1 B DT D 5 16.247 27.006 13.341 0.43 74.43 N ANISOU 1173 N1 B DT D 5 10302 8104 9875 1619 1471 363 N ATOM 1174 C2 A DT D 5 16.611 26.815 13.470 0.57 73.73 C ANISOU 1174 C2 A DT D 5 10247 8039 9726 1583 1462 249 C ATOM 1175 C2 B DT D 5 17.441 26.393 13.035 0.43 73.83 C ANISOU 1175 C2 B DT D 5 10349 8170 9533 1525 1323 7 C ATOM 1176 O2 A DT D 5 16.745 25.704 13.009 0.57 75.70 O ANISOU 1176 O2 A DT D 5 10451 8376 9934 1542 1074 124 O ATOM 1177 O2 B DT D 5 17.515 25.301 12.506 0.43 79.88 O ANISOU 1177 O2 B DT D 5 11090 9015 10245 1525 934 -113 O ATOM 1178 N3 A DT D 5 17.672 27.550 13.919 0.57 73.06 N ANISOU 1178 N3 A DT D 5 10378 7948 9434 1509 1779 44 N ATOM 1179 N3 B DT D 5 18.557 27.109 13.371 0.43 70.97 N ANISOU 1179 N3 B DT D 5 10164 7848 8951 1443 1627 -177 N ATOM 1180 C4 A DT D 5 17.639 28.819 14.467 0.57 73.79 C ANISOU 1180 C4 A DT D 5 10651 7867 9518 1538 2160 145 C ATOM 1181 C4 B DT D 5 18.609 28.353 13.975 0.43 72.46 C ANISOU 1181 C4 B DT D 5 10507 7881 9142 1418 2002 -79 C ATOM 1182 O4 A DT D 5 18.659 29.401 14.837 0.57 73.41 O ANISOU 1182 O4 A DT D 5 10834 7792 9266 1400 2343 -20 O ATOM 1183 O4 B DT D 5 19.675 28.913 14.238 0.43 66.62 O ANISOU 1183 O4 B DT D 5 9952 7168 8193 1273 2174 -216 O ATOM 1184 C5 A DT D 5 16.320 29.408 14.572 0.57 75.85 C ANISOU 1184 C5 A DT D 5 10828 7976 10016 1749 2298 493 C ATOM 1185 C5 B DT D 5 17.324 28.946 14.270 0.43 74.06 C ANISOU 1185 C5 B DT D 5 10658 7885 9596 1584 2152 231 C ATOM 1186 C7 A DT D 5 16.144 30.783 15.153 0.57 77.59 C ANISOU 1186 C7 A DT D 5 11326 7946 10209 1882 2698 604 C ATOM 1187 C7 B DT D 5 17.251 30.293 14.928 0.43 74.96 C ANISOU 1187 C7 B DT D 5 11038 7756 9686 1650 2540 327 C ATOM 1188 C6 A DT D 5 15.272 28.680 14.148 0.57 76.26 C ANISOU 1188 C6 A DT D 5 10572 8105 10296 1832 2032 738 C ATOM 1189 C6 B DT D 5 16.216 28.252 13.943 0.43 75.55 C ANISOU 1189 C6 B DT D 5 10578 8107 10020 1688 1908 455 C ATOM 1190 P DC D 6 11.632 24.114 14.212 1.00108.18 P ANISOU 1190 P DC D 6 13339 12412 15353 1564 367 1847 P ATOM 1191 OP1 DC D 6 10.514 23.253 13.756 1.00102.30 O ANISOU 1191 OP1 DC D 6 12298 11704 14869 1410 -212 2323 O ATOM 1192 OP2 DC D 6 11.429 24.947 15.414 1.00107.51 O ANISOU 1192 OP2 DC D 6 13157 12348 15343 1770 978 1976 O ATOM 1193 O5' DC D 6 12.892 23.181 14.482 1.00 96.99 O ANISOU 1193 O5' DC D 6 12189 10951 13713 1416 178 1292 O ATOM 1194 C5' DC D 6 13.726 22.802 13.396 1.00 83.90 C ANISOU 1194 C5' DC D 6 10840 9269 11769 1372 -133 912 C ATOM 1195 C4' DC D 6 14.965 22.099 13.902 1.00 70.43 C ANISOU 1195 C4' DC D 6 9338 7565 9858 1325 -151 428 C ATOM 1196 O4' DC D 6 15.981 23.080 14.253 1.00 68.73 O ANISOU 1196 O4' DC D 6 9273 7411 9429 1398 393 159 O ATOM 1197 C3' DC D 6 14.753 21.249 15.152 1.00 66.95 C ANISOU 1197 C3' DC D 6 8715 7088 9635 1207 -244 505 C ATOM 1198 O3' DC D 6 15.489 20.071 15.029 1.00 72.18 O ANISOU 1198 O3' DC D 6 9570 7696 10158 1138 -660 166 O ATOM 1199 C2' DC D 6 15.310 22.135 16.268 1.00 66.58 C ANISOU 1199 C2' DC D 6 8677 7080 9540 1269 390 386 C ATOM 1200 C1' DC D 6 16.469 22.798 15.547 1.00 66.46 C ANISOU 1200 C1' DC D 6 8956 7111 9185 1331 588 18 C ATOM 1201 N1 DC D 6 16.940 24.079 16.163 1.00 61.55 N ANISOU 1201 N1 DC D 6 8446 6477 8462 1373 1160 -33 N ATOM 1202 C2 DC D 6 18.241 24.170 16.672 1.00 67.28 C ANISOU 1202 C2 DC D 6 9352 7243 8967 1285 1348 -367 C ATOM 1203 O2 DC D 6 18.981 23.178 16.627 1.00 70.75 O ANISOU 1203 O2 DC D 6 9810 7763 9308 1226 1090 -617 O ATOM 1204 N3 DC D 6 18.656 25.350 17.203 1.00 73.33 N ANISOU 1204 N3 DC D 6 10292 7943 9626 1268 1777 -383 N ATOM 1205 C4 DC D 6 17.826 26.403 17.235 1.00 67.32 C ANISOU 1205 C4 DC D 6 9567 7055 8954 1397 2039 -124 C ATOM 1206 N4 DC D 6 18.280 27.548 17.767 1.00 60.75 N ANISOU 1206 N4 DC D 6 9015 6086 7980 1380 2400 -167 N ATOM 1207 C5 DC D 6 16.502 26.325 16.719 1.00 58.21 C ANISOU 1207 C5 DC D 6 8188 5897 8032 1548 1909 218 C ATOM 1208 C6 DC D 6 16.107 25.158 16.197 1.00 65.05 C ANISOU 1208 C6 DC D 6 8846 6852 9018 1499 1459 272 C ATOM 1209 P DT D 7 15.162 18.813 15.964 1.00 62.96 P ANISOU 1209 P DT D 7 8259 6444 9221 956 -1045 277 P ATOM 1210 OP1 DT D 7 15.328 17.625 15.112 1.00 62.67 O ANISOU 1210 OP1 DT D 7 8491 6255 9064 917 -1737 96 O ATOM 1211 OP2 DT D 7 13.878 19.107 16.651 1.00 73.77 O ANISOU 1211 OP2 DT D 7 9222 7869 10938 881 -931 848 O ATOM 1212 O5' DT D 7 16.336 18.825 17.033 1.00 40.32 O ANISOU 1212 O5' DT D 7 5465 3628 6227 965 -664 -93 O ATOM 1213 C5' DT D 7 17.678 18.782 16.598 1.00 45.25 C ANISOU 1213 C5' DT D 7 6376 4301 6518 1075 -592 -568 C ATOM 1214 C4' DT D 7 18.611 19.064 17.752 1.00 49.66 C ANISOU 1214 C4' DT D 7 6920 4933 7016 1027 -166 -767 C ATOM 1215 O4' DT D 7 18.671 20.483 17.974 1.00 52.85 O ANISOU 1215 O4' DT D 7 7315 5401 7364 1059 398 -685 O ATOM 1216 C3' DT D 7 18.167 18.466 19.082 1.00 48.33 C ANISOU 1216 C3' DT D 7 6551 4704 7109 859 -219 -594 C ATOM 1217 O3' DT D 7 19.031 17.446 19.438 1.00 43.14 O ANISOU 1217 O3' DT D 7 5995 4018 6378 809 -473 -881 O ATOM 1218 C2' DT D 7 18.231 19.634 20.093 1.00 39.73 C ANISOU 1218 C2' DT D 7 5405 3670 6022 850 410 -509 C ATOM 1219 C1' DT D 7 18.964 20.713 19.323 1.00 38.49 C ANISOU 1219 C1' DT D 7 5456 3571 5598 957 719 -698 C ATOM 1220 N1 DT D 7 18.502 22.089 19.648 1.00 41.12 N ANISOU 1220 N1 DT D 7 5813 3869 5943 1021 1204 -499 N ATOM 1221 C2 DT D 7 19.393 22.990 20.168 1.00 34.04 C ANISOU 1221 C2 DT D 7 5130 2956 4848 970 1590 -666 C ATOM 1222 O2 DT D 7 20.560 22.724 20.398 1.00 32.81 O ANISOU 1222 O2 DT D 7 5075 2864 4526 849 1574 -928 O ATOM 1223 N3 DT D 7 18.871 24.233 20.420 1.00 35.10 N ANISOU 1223 N3 DT D 7 5375 2984 4977 1070 1975 -485 N ATOM 1224 C4 DT D 7 17.578 24.661 20.223 1.00 43.95 C ANISOU 1224 C4 DT D 7 6363 4061 6276 1261 2064 -146 C ATOM 1225 O4 DT D 7 17.227 25.815 20.484 1.00 45.77 O ANISOU 1225 O4 DT D 7 6757 4175 6460 1408 2434 -18 O ATOM 1226 C5 DT D 7 16.681 23.664 19.674 1.00 43.23 C ANISOU 1226 C5 DT D 7 5956 4055 6416 1278 1658 75 C ATOM 1227 C7 DT D 7 15.250 23.998 19.406 1.00 41.60 C ANISOU 1227 C7 DT D 7 5507 3865 6436 1452 1688 539 C ATOM 1228 C6 DT D 7 17.182 22.439 19.415 1.00 46.76 C ANISOU 1228 C6 DT D 7 6355 4553 6858 1135 1224 -119 C HETATM 1229 N1 5CM D 8 18.779 20.511 24.085 1.00 33.11 N ANISOU 1229 N1 5CM D 8 4590 2811 5180 624 1411 -471 N HETATM 1230 C2 5CM D 8 19.475 21.816 24.106 1.00 47.84 C ANISOU 1230 C2 5CM D 8 6773 4611 6793 661 1832 -638 C HETATM 1231 N3 5CM D 8 18.713 23.057 23.798 1.00 34.33 N ANISOU 1231 N3 5CM D 8 5161 2829 5055 877 2170 -436 N HETATM 1232 C4 5CM D 8 17.335 23.007 23.440 1.00 36.24 C ANISOU 1232 C4 5CM D 8 5130 3120 5519 1069 2128 -61 C HETATM 1233 C5 5CM D 8 16.627 21.691 23.415 1.00 40.07 C ANISOU 1233 C5 5CM D 8 5238 3719 6269 988 1695 164 C HETATM 1234 C5A 5CM D 8 15.146 21.610 23.052 1.00 39.42 C ANISOU 1234 C5A 5CM D 8 4803 3731 6443 1127 1591 673 C HETATM 1235 C6 5CM D 8 17.375 20.450 23.729 1.00 41.62 C ANISOU 1235 C6 5CM D 8 5403 3927 6484 752 1315 -64 C HETATM 1236 O2 5CM D 8 20.626 21.856 24.385 1.00 31.45 O ANISOU 1236 O2 5CM D 8 4873 2534 4544 509 1866 -895 O HETATM 1237 N4 5CM D 8 16.667 24.259 23.147 1.00 38.12 N ANISOU 1237 N4 5CM D 8 5478 3286 5719 1324 2481 135 N HETATM 1238 C1' 5CM D 8 19.577 19.327 24.387 1.00 31.86 C ANISOU 1238 C1' 5CM D 8 4403 2670 5031 443 1061 -690 C HETATM 1239 C2' 5CM D 8 18.769 17.985 24.567 1.00 32.90 C ANISOU 1239 C2' 5CM D 8 4257 2806 5439 353 573 -461 C HETATM 1240 C3' 5CM D 8 19.932 17.029 24.406 1.00 35.73 C ANISOU 1240 C3' 5CM D 8 4739 3133 5703 260 230 -822 C HETATM 1241 C4' 5CM D 8 20.690 17.520 23.403 1.00 31.14 C ANISOU 1241 C4' 5CM D 8 4348 2584 4899 392 309 -1076 C HETATM 1242 O4' 5CM D 8 20.323 19.083 23.348 1.00 41.96 O ANISOU 1242 O4' 5CM D 8 5787 3972 6183 480 842 -938 O HETATM 1243 O3' 5CM D 8 20.710 17.213 25.648 1.00 37.23 O ANISOU 1243 O3' 5CM D 8 4996 3348 5804 116 518 -946 O HETATM 1244 C5' 5CM D 8 20.386 16.900 22.078 1.00 38.07 C ANISOU 1244 C5' 5CM D 8 5264 3420 5782 527 -140 -1106 C HETATM 1245 O5' 5CM D 8 19.000 16.761 21.905 1.00 34.15 O ANISOU 1245 O5' 5CM D 8 4588 2861 5524 502 -346 -730 O HETATM 1246 P 5CM D 8 18.521 16.285 20.415 1.00 43.83 P ANISOU 1246 P 5CM D 8 5918 4001 6735 611 -850 -707 P HETATM 1247 OP1 5CM D 8 19.198 15.011 19.985 1.00 55.35 O ANISOU 1247 OP1 5CM D 8 7606 5341 8085 650 -1393 -1012 O HETATM 1248 OP2 5CM D 8 17.002 16.260 20.335 1.00 45.33 O ANISOU 1248 OP2 5CM D 8 5852 4161 7211 521 -1055 -195 O ATOM 1249 P DG D 9 21.048 15.974 26.604 1.00 61.39 P ANISOU 1249 P DG D 9 8465 5498 9364 1681 -1328 109 P ATOM 1250 OP1 DG D 9 21.615 14.882 25.773 1.00 67.48 O ANISOU 1250 OP1 DG D 9 9167 6330 10143 1675 -1609 -57 O ATOM 1251 OP2 DG D 9 19.918 15.690 27.504 1.00 55.03 O ANISOU 1251 OP2 DG D 9 8103 4197 8608 1650 -966 394 O ATOM 1252 O5' DG D 9 22.167 16.585 27.564 1.00 47.68 O ANISOU 1252 O5' DG D 9 6946 3918 7251 1883 -1514 -7 O ATOM 1253 C5' DG D 9 23.405 17.023 27.034 1.00 39.12 C ANISOU 1253 C5' DG D 9 5575 3274 6016 1872 -1827 -260 C ATOM 1254 C4' DG D 9 23.970 18.140 27.886 1.00 38.33 C ANISOU 1254 C4' DG D 9 5578 3290 5696 1958 -1881 -325 C ATOM 1255 O4' DG D 9 23.182 19.344 27.669 1.00 45.49 O ANISOU 1255 O4' DG D 9 6163 4260 6861 1821 -1635 -239 O ATOM 1256 C3' DG D 9 23.931 17.881 29.380 1.00 42.24 C ANISOU 1256 C3' DG D 9 6698 3456 5894 2198 -1858 -231 C ATOM 1257 O3' DG D 9 25.059 18.460 29.966 1.00 42.60 O ANISOU 1257 O3' DG D 9 6882 3701 5605 2324 -2125 -419 O ATOM 1258 C2' DG D 9 22.629 18.561 29.825 1.00 56.20 C ANISOU 1258 C2' DG D 9 8516 4963 7872 2156 -1456 -48 C ATOM 1259 C1' DG D 9 22.529 19.741 28.860 1.00 46.58 C ANISOU 1259 C1' DG D 9 6672 4067 6958 1975 -1409 -124 C ATOM 1260 N9 DG D 9 21.162 20.119 28.495 1.00 57.29 N ANISOU 1260 N9 DG D 9 7792 5276 8700 1854 -1013 51 N ATOM 1261 C8 DG D 9 20.119 19.276 28.204 1.00 58.74 C ANISOU 1261 C8 DG D 9 8027 5197 9094 1769 -777 236 C ATOM 1262 N7 DG D 9 19.028 19.905 27.861 1.00 55.24 N ANISOU 1262 N7 DG D 9 7265 4738 8984 1614 -490 339 N ATOM 1263 C5 DG D 9 19.374 21.246 27.908 1.00 43.42 C ANISOU 1263 C5 DG D 9 5519 3494 7485 1637 -524 215 C ATOM 1264 C6 DG D 9 18.597 22.391 27.635 1.00 40.82 C ANISOU 1264 C6 DG D 9 4759 3284 7467 1475 -287 255 C ATOM 1265 O6 DG D 9 17.401 22.456 27.287 1.00 38.24 O ANISOU 1265 O6 DG D 9 4096 2922 7510 1261 76 450 O ATOM 1266 N1 DG D 9 19.330 23.550 27.803 1.00 37.38 N ANISOU 1266 N1 DG D 9 4266 3028 6909 1538 -449 98 N ATOM 1267 C2 DG D 9 20.645 23.603 28.180 1.00 43.40 C ANISOU 1267 C2 DG D 9 5263 3878 7349 1674 -772 -55 C ATOM 1268 N2 DG D 9 21.180 24.821 28.277 1.00 34.51 N ANISOU 1268 N2 DG D 9 4012 2883 6219 1644 -897 -177 N ATOM 1269 N3 DG D 9 21.384 22.538 28.439 1.00 42.74 N ANISOU 1269 N3 DG D 9 5486 3756 6998 1777 -992 -97 N ATOM 1270 C4 DG D 9 20.682 21.397 28.288 1.00 45.88 C ANISOU 1270 C4 DG D 9 6009 3948 7473 1773 -838 50 C HETATM 1271 N1 5CM D 10 20.720 22.128 31.988 1.00 52.89 N ANISOU 1271 N1 5CM D 10 8394 4124 7577 2357 -582 -131 N HETATM 1272 C2 5CM D 10 19.725 23.164 31.595 1.00 52.84 C ANISOU 1272 C2 5CM D 10 7964 4070 8043 2272 -215 -121 C HETATM 1273 N3 5CM D 10 18.388 22.751 31.095 1.00 52.09 N ANISOU 1273 N3 5CM D 10 7619 3886 8287 2076 233 145 N HETATM 1274 C4 5CM D 10 18.050 21.356 30.961 1.00 45.62 C ANISOU 1274 C4 5CM D 10 7015 2959 7359 1953 283 372 C HETATM 1275 C5 5CM D 10 19.035 20.324 31.346 1.00 59.23 C ANISOU 1275 C5 5CM D 10 9269 4569 8667 2125 -126 339 C HETATM 1276 C5A 5CM D 10 18.658 18.843 31.205 1.00 60.02 C ANISOU 1276 C5A 5CM D 10 9635 4461 8709 1993 -92 582 C HETATM 1277 C6 5CM D 10 20.379 20.730 31.847 1.00 46.73 C ANISOU 1277 C6 5CM D 10 7831 3185 6738 2300 -545 89 C HETATM 1278 O2 5CM D 10 19.975 24.321 31.687 1.00 56.93 O ANISOU 1278 O2 5CM D 10 8295 4678 8659 2291 -242 -293 O HETATM 1279 N4 5CM D 10 16.748 20.970 30.470 1.00 45.86 N ANISOU 1279 N4 5CM D 10 6749 2982 7693 1660 720 644 N HETATM 1280 C1' 5CM D 10 22.055 22.511 32.462 1.00 47.64 C ANISOU 1280 C1' 5CM D 10 7908 3662 6531 2490 -1003 -351 C HETATM 1281 C2' 5CM D 10 22.409 21.987 33.901 1.00 50.47 C ANISOU 1281 C2' 5CM D 10 9108 3821 6247 2759 -1048 -367 C HETATM 1282 C3' 5CM D 10 23.916 21.786 33.861 1.00 55.90 C ANISOU 1282 C3' 5CM D 10 9814 4799 6626 2849 -1616 -503 C HETATM 1283 C4' 5CM D 10 24.287 21.974 32.578 1.00 49.74 C ANISOU 1283 C4' 5CM D 10 8358 4325 6215 2630 -1795 -551 C HETATM 1284 O4' 5CM D 10 22.944 21.943 31.704 1.00 43.86 O ANISOU 1284 O4' 5CM D 10 7176 3457 6030 2407 -1372 -363 O HETATM 1285 O3' 5CM D 10 24.605 22.809 34.696 1.00 61.05 O ANISOU 1285 O3' 5CM D 10 10747 5503 6944 3034 -1798 -749 O HETATM 1286 C5' 5CM D 10 25.177 20.883 32.092 1.00 50.89 C ANISOU 1286 C5' 5CM D 10 8455 4662 6219 2608 -2105 -561 C HETATM 1287 O5' 5CM D 10 24.536 19.642 32.193 1.00 57.21 O ANISOU 1287 O5' 5CM D 10 9503 5202 7034 2621 -1932 -348 O HETATM 1288 P 5CM D 10 25.336 18.367 31.548 1.00 50.27 P ANISOU 1288 P 5CM D 10 8537 4448 6114 2598 -2196 -385 P HETATM 1289 OP1 5CM D 10 26.805 18.622 31.708 1.00 49.14 O ANISOU 1289 OP1 5CM D 10 8411 4590 5671 2697 -2552 -644 O HETATM 1290 OP2 5CM D 10 24.867 17.075 32.172 1.00 58.56 O ANISOU 1290 OP2 5CM D 10 10089 5131 7030 2692 -2099 -162 O ATOM 1291 P DG D 11 24.448 22.814 36.298 1.00 67.48 P ANISOU 1291 P DG D 11 12397 6076 7167 3271 -1607 -791 P ATOM 1292 OP1 DG D 11 25.596 23.564 36.841 1.00 69.34 O ANISOU 1292 OP1 DG D 11 12788 6529 7030 3388 -1992 -1060 O ATOM 1293 OP2 DG D 11 24.146 21.446 36.767 1.00 59.17 O ANISOU 1293 OP2 DG D 11 11785 4861 5835 3306 -1504 -484 O ATOM 1294 O5' DG D 11 23.113 23.657 36.562 1.00 65.74 O ANISOU 1294 O5' DG D 11 12057 5728 7192 3097 -962 -845 O ATOM 1295 C5' DG D 11 23.066 25.031 36.293 1.00 56.52 C ANISOU 1295 C5' DG D 11 10536 4597 6343 3048 -915 -1112 C ATOM 1296 C4' DG D 11 21.698 25.573 36.637 1.00 59.23 C ANISOU 1296 C4' DG D 11 10821 4794 6890 2948 -254 -1123 C ATOM 1297 O4' DG D 11 20.697 24.951 35.781 1.00 61.14 O ANISOU 1297 O4' DG D 11 10695 4956 7578 2806 27 -816 O ATOM 1298 C3' DG D 11 21.230 25.289 38.065 1.00 66.52 C ANISOU 1298 C3' DG D 11 12349 5708 7218 2979 140 -1134 C ATOM 1299 O3' DG D 11 20.387 26.324 38.476 1.00 76.20 O ANISOU 1299 O3' DG D 11 13488 6878 8587 2963 621 -1355 O ATOM 1300 C2' DG D 11 20.425 24.016 37.884 1.00 72.74 C ANISOU 1300 C2' DG D 11 13189 6422 8028 2872 391 -726 C ATOM 1301 C1' DG D 11 19.699 24.381 36.606 1.00 67.42 C ANISOU 1301 C1' DG D 11 11833 5685 8100 2747 544 -646 C ATOM 1302 N9 DG D 11 19.090 23.249 35.925 1.00 67.78 N ANISOU 1302 N9 DG D 11 11729 5666 8358 2595 641 -283 N ATOM 1303 C8 DG D 11 19.468 21.936 36.007 1.00 59.34 C ANISOU 1303 C8 DG D 11 11003 4533 7011 2596 405 -54 C ATOM 1304 N7 DG D 11 18.726 21.140 35.291 1.00 58.20 N ANISOU 1304 N7 DG D 11 10642 4298 7172 2410 563 225 N ATOM 1305 C5 DG D 11 17.797 21.977 34.701 1.00 59.32 C ANISOU 1305 C5 DG D 11 10234 4503 7801 2276 932 203 C ATOM 1306 C6 DG D 11 16.732 21.680 33.828 1.00 62.43 C ANISOU 1306 C6 DG D 11 10172 4897 8650 2031 1233 446 C ATOM 1307 O6 DG D 11 16.400 20.576 33.372 1.00 54.98 O ANISOU 1307 O6 DG D 11 9242 3874 7772 1854 1227 705 O ATOM 1308 N1 DG D 11 16.026 22.829 33.466 1.00 54.35 N ANISOU 1308 N1 DG D 11 8633 3970 8049 1993 1551 365 N ATOM 1309 C2 DG D 11 16.306 24.094 33.904 1.00 58.84 C ANISOU 1309 C2 DG D 11 9170 4559 8628 2175 1572 63 C ATOM 1310 N2 DG D 11 15.509 25.086 33.444 1.00 54.58 N ANISOU 1310 N2 DG D 11 8099 4056 8585 2138 1887 44 N ATOM 1311 N3 DG D 11 17.301 24.380 34.733 1.00 61.80 N ANISOU 1311 N3 DG D 11 9999 4913 8567 2375 1292 -201 N ATOM 1312 C4 DG D 11 17.998 23.279 35.089 1.00 57.13 C ANISOU 1312 C4 DG D 11 9877 4295 7533 2410 987 -101 C ATOM 1313 P DA D 12 20.821 27.305 39.664 1.00 89.79 P ANISOU 1313 P DA D 12 15608 8657 9850 3062 656 -1794 P ATOM 1314 OP1 DA D 12 22.102 27.927 39.243 1.00 81.64 O ANISOU 1314 OP1 DA D 12 14466 7663 8892 3102 45 -2011 O ATOM 1315 OP2 DA D 12 20.689 26.552 40.937 1.00 83.31 O ANISOU 1315 OP2 DA D 12 15386 7982 8286 3069 870 -1714 O ATOM 1316 O5' DA D 12 19.695 28.425 39.643 1.00 72.46 O ANISOU 1316 O5' DA D 12 13109 6319 8104 3068 1205 -2013 O ATOM 1317 C5' DA D 12 19.479 29.178 38.465 1.00 69.97 C ANISOU 1317 C5' DA D 12 12176 5846 8563 3040 1134 -2011 C ATOM 1318 C4' DA D 12 17.996 29.354 38.204 1.00 72.43 C ANISOU 1318 C4' DA D 12 12130 6075 9316 3019 1759 -1876 C ATOM 1319 O4' DA D 12 17.441 28.126 37.677 1.00 76.37 O ANISOU 1319 O4' DA D 12 12487 6662 9870 2881 1873 -1415 O ATOM 1320 C3' DA D 12 17.150 29.690 39.428 1.00 81.02 C ANISOU 1320 C3' DA D 12 13540 7196 10047 3116 2363 -2111 C ATOM 1321 O3' DA D 12 16.128 30.555 39.035 1.00 86.31 O ANISOU 1321 O3' DA D 12 13716 7764 11315 3149 2750 -2166 O ATOM 1322 C2' DA D 12 16.577 28.332 39.829 1.00 79.16 C ANISOU 1322 C2' DA D 12 13545 7153 9379 3002 2631 -1728 C ATOM 1323 C1' DA D 12 16.331 27.738 38.460 1.00 79.13 C ANISOU 1323 C1' DA D 12 13030 7093 9945 2859 2479 -1315 C ATOM 1324 N9 DA D 12 16.262 26.287 38.434 1.00 80.74 N ANISOU 1324 N9 DA D 12 13441 7385 9853 2708 2426 -908 N ATOM 1325 C8 DA D 12 17.037 25.406 39.133 1.00 79.72 C ANISOU 1325 C8 DA D 12 13870 7321 9098 2712 2141 -833 C ATOM 1326 N7 DA D 12 16.759 24.151 38.885 1.00 73.93 N ANISOU 1326 N7 DA D 12 13215 6582 8296 2561 2134 -425 N ATOM 1327 C5 DA D 12 15.740 24.216 37.949 1.00 72.79 C ANISOU 1327 C5 DA D 12 12514 6402 8740 2424 2438 -236 C ATOM 1328 C6 DA D 12 15.000 23.226 37.272 1.00 72.37 C ANISOU 1328 C6 DA D 12 12254 6329 8916 2194 2578 175 C ATOM 1329 N6 DA D 12 15.185 21.903 37.440 1.00 71.42 N ANISOU 1329 N6 DA D 12 12509 6148 8478 2072 2411 477 N ATOM 1330 N1 DA D 12 14.056 23.645 36.412 1.00 66.61 N ANISOU 1330 N1 DA D 12 10915 5630 8764 2082 2881 275 N ATOM 1331 C2 DA D 12 13.869 24.954 36.236 1.00 66.73 C ANISOU 1331 C2 DA D 12 10559 5653 9141 2223 3026 6 C ATOM 1332 N3 DA D 12 14.496 25.968 36.809 1.00 67.55 N ANISOU 1332 N3 DA D 12 10833 5711 9121 2449 2912 -397 N ATOM 1333 C4 DA D 12 15.428 25.528 37.660 1.00 74.76 C ANISOU 1333 C4 DA D 12 12350 6634 9421 2524 2619 -511 C ATOM 1334 P DG D 13 15.584 31.661 40.047 1.00 86.18 P ANISOU 1334 P DG D 13 13771 7769 11203 3260 3108 -2611 P ATOM 1335 OP1 DG D 13 16.300 32.922 39.743 1.00 96.26 O ANISOU 1335 OP1 DG D 13 14809 8887 12878 3250 2641 -2925 O ATOM 1336 OP2 DG D 13 15.579 31.094 41.416 1.00 88.81 O ANISOU 1336 OP2 DG D 13 14779 8290 10676 3329 3424 -2772 O ATOM 1337 O5' DG D 13 14.067 31.824 39.624 1.00 96.42 O ANISOU 1337 O5' DG D 13 14543 9110 12981 3269 3646 -2391 O ATOM 1338 C5' DG D 13 13.095 31.136 40.337 1.00 92.57 C ANISOU 1338 C5' DG D 13 14261 8815 12098 3306 4287 -2278 C ATOM 1339 C4' DG D 13 11.998 30.672 39.421 1.00 85.60 C ANISOU 1339 C4' DG D 13 12839 7992 11693 3202 4606 -1809 C ATOM 1340 O4' DG D 13 12.347 29.375 38.888 1.00 83.69 O ANISOU 1340 O4' DG D 13 12707 7773 11319 3021 4414 -1389 O ATOM 1341 C3' DG D 13 10.673 30.472 40.121 1.00 95.46 C ANISOU 1341 C3' DG D 13 14059 9502 12709 3239 5332 -1749 C ATOM 1342 O3' DG D 13 9.627 30.601 39.206 1.00 90.66 O ANISOU 1342 O3' DG D 13 12782 8959 12705 3147 5520 -1413 O ATOM 1343 C2' DG D 13 10.799 29.048 40.630 1.00 94.65 C ANISOU 1343 C2' DG D 13 14439 9599 11926 3066 5424 -1450 C ATOM 1344 C1' DG D 13 11.523 28.383 39.469 1.00 86.92 C ANISOU 1344 C1' DG D 13 13297 8455 11275 2874 4837 -1099 C ATOM 1345 N9 DG D 13 12.351 27.254 39.880 1.00 84.28 N ANISOU 1345 N9 DG D 13 13502 8181 10341 2724 4467 -926 N ATOM 1346 C8 DG D 13 13.432 27.276 40.729 1.00 91.09 C ANISOU 1346 C8 DG D 13 14931 9040 10639 2814 4134 -1202 C ATOM 1347 N7 DG D 13 13.968 26.100 40.919 1.00 93.68 N ANISOU 1347 N7 DG D 13 15636 9424 10534 2667 3838 -907 N ATOM 1348 C5 DG D 13 13.188 25.247 40.151 1.00 87.50 C ANISOU 1348 C5 DG D 13 14544 8646 10055 2453 3987 -438 C ATOM 1349 C6 DG D 13 13.284 23.852 39.956 1.00 86.39 C ANISOU 1349 C6 DG D 13 14611 8491 9722 2232 3790 9 C ATOM 1350 O6 DG D 13 14.108 23.061 40.442 1.00 91.40 O ANISOU 1350 O6 DG D 13 15749 9098 9881 2216 3430 108 O ATOM 1351 N1 DG D 13 12.293 23.385 39.094 1.00 79.39 N ANISOU 1351 N1 DG D 13 13278 7611 9274 2014 4040 368 N ATOM 1352 C2 DG D 13 11.332 24.172 38.503 1.00 78.83 C ANISOU 1352 C2 DG D 13 12605 7603 9743 2022 4433 337 C ATOM 1353 N2 DG D 13 10.464 23.549 37.703 1.00 77.43 N ANISOU 1353 N2 DG D 13 12042 7478 9900 1761 4619 733 N ATOM 1354 N3 DG D 13 11.231 25.477 38.680 1.00 79.94 N ANISOU 1354 N3 DG D 13 12536 7744 10095 2267 4618 -53 N ATOM 1355 C4 DG D 13 12.188 25.946 39.510 1.00 83.33 C ANISOU 1355 C4 DG D 13 13424 8122 10117 2468 4377 -441 C ATOM 1356 P DA D 14 8.213 31.163 39.702 1.00109.79 P ANISOU 1356 P DA D 14 14895 11640 15180 3236 6073 -1474 P ATOM 1357 OP1 DA D 14 7.933 32.401 38.938 1.00116.35 O ANISOU 1357 OP1 DA D 14 15184 12322 16702 3308 5812 -1548 O ATOM 1358 OP2 DA D 14 8.228 31.202 41.183 1.00114.04 O ANISOU 1358 OP2 DA D 14 15963 12369 14997 3379 6390 -1869 O ATOM 1359 O5' DA D 14 7.196 30.027 39.241 1.00113.34 O ANISOU 1359 O5' DA D 14 15069 12353 15642 2997 6476 -894 O ATOM 1360 C5' DA D 14 7.309 29.476 37.937 1.00102.08 C ANISOU 1360 C5' DA D 14 13281 10824 14682 2772 6203 -457 C ATOM 1361 C4' DA D 14 6.671 28.106 37.878 1.00 96.89 C ANISOU 1361 C4' DA D 14 12644 10418 13753 2505 6569 25 C ATOM 1362 O4' DA D 14 7.610 27.115 38.366 1.00100.00 O ANISOU 1362 O4' DA D 14 13685 10754 13555 2380 6282 62 O ATOM 1363 C3' DA D 14 5.403 27.941 38.721 1.00 99.80 C ANISOU 1363 C3' DA D 14 12975 11199 13745 2441 7115 117 C ATOM 1364 O3' DA D 14 4.461 27.167 37.999 1.00 94.39 O ANISOU 1364 O3' DA D 14 11885 10738 13242 2088 7182 646 O ATOM 1365 C2' DA D 14 5.908 27.201 39.961 1.00103.91 C ANISOU 1365 C2' DA D 14 14248 11834 13400 2452 7350 9 C ATOM 1366 C1' DA D 14 6.982 26.319 39.347 1.00105.06 C ANISOU 1366 C1' DA D 14 14663 11716 13539 2222 6679 238 C ATOM 1367 N9 DA D 14 8.000 25.865 40.291 1.00108.94 N ANISOU 1367 N9 DA D 14 15890 12157 13346 2230 6363 72 N ATOM 1368 C8 DA D 14 8.710 26.629 41.175 1.00110.18 C ANISOU 1368 C8 DA D 14 16432 12260 13171 2505 6280 -441 C ATOM 1369 N7 DA D 14 9.573 25.945 41.893 1.00110.03 N ANISOU 1369 N7 DA D 14 17031 12255 12521 2424 5960 -432 N ATOM 1370 C5 DA D 14 9.414 24.643 41.448 1.00106.88 C ANISOU 1370 C5 DA D 14 16672 11866 12073 2099 5821 120 C ATOM 1371 C6 DA D 14 10.034 23.431 41.811 1.00101.34 C ANISOU 1371 C6 DA D 14 16499 11135 10872 1897 5476 422 C ATOM 1372 N6 DA D 14 10.983 23.336 42.747 1.00104.47 N ANISOU 1372 N6 DA D 14 17476 11549 10670 1995 5199 233 N ATOM 1373 N1 DA D 14 9.640 22.316 41.167 1.00 96.28 N ANISOU 1373 N1 DA D 14 15763 10436 10382 1586 5413 935 N ATOM 1374 C2 DA D 14 8.693 22.406 40.229 1.00 98.37 C ANISOU 1374 C2 DA D 14 15430 10734 11212 1455 5683 1133 C ATOM 1375 N3 DA D 14 8.038 23.482 39.803 1.00102.95 N ANISOU 1375 N3 DA D 14 15445 11396 12276 1618 6017 926 N ATOM 1376 C4 DA D 14 8.450 24.578 40.459 1.00107.66 C ANISOU 1376 C4 DA D 14 16166 11988 12751 1959 6067 415 C ATOM 1377 P DA D 15 2.925 27.098 38.460 1.00121.43 P ANISOU 1377 P DA D 15 15018 14642 16478 1960 7562 813 P ATOM 1378 OP1 DA D 15 2.126 27.450 37.266 1.00120.48 O ANISOU 1378 OP1 DA D 15 14242 14561 16974 1836 7320 1045 O ATOM 1379 OP2 DA D 15 2.744 27.849 39.727 1.00123.50 O ANISOU 1379 OP2 DA D 15 15498 15077 16348 2271 7910 362 O ATOM 1380 O5' DA D 15 2.703 25.543 38.761 1.00120.13 O ANISOU 1380 O5' DA D 15 15162 14709 15773 1539 7669 1256 O ATOM 1381 C5' DA D 15 3.065 24.579 37.772 1.00108.47 C ANISOU 1381 C5' DA D 15 13662 13046 14505 1213 7307 1631 C ATOM 1382 C4' DA D 15 3.158 23.187 38.368 1.00102.89 C ANISOU 1382 C4' DA D 15 13475 12437 13180 867 7354 1958 C ATOM 1383 O4' DA D 15 4.295 23.111 39.270 1.00101.14 O ANISOU 1383 O4' DA D 15 13972 12025 12431 1070 7459 1762 O ATOM 1384 C3' DA D 15 1.939 22.739 39.178 1.00111.12 C ANISOU 1384 C3' DA D 15 14468 13990 13763 622 7637 2142 C ATOM 1385 O3' DA D 15 1.626 21.402 38.839 1.00110.34 O ANISOU 1385 O3' DA D 15 14442 13953 13531 127 7380 2581 O ATOM 1386 C2' DA D 15 2.418 22.852 40.628 1.00114.39 C ANISOU 1386 C2' DA D 15 15488 14508 13468 816 7965 1917 C ATOM 1387 C1' DA D 15 3.890 22.510 40.481 1.00108.48 C ANISOU 1387 C1' DA D 15 15316 13278 12622 907 7706 1885 C ATOM 1388 N9 DA D 15 4.731 23.023 41.563 1.00111.78 N ANISOU 1388 N9 DA D 15 16281 13662 12531 1229 7719 1449 N ATOM 1389 C8 DA D 15 4.702 24.279 42.112 1.00113.46 C ANISOU 1389 C8 DA D 15 16398 13970 12742 1639 7991 905 C ATOM 1390 N7 DA D 15 5.582 24.458 43.070 1.00115.79 N ANISOU 1390 N7 DA D 15 17261 14225 12507 1805 7797 554 N ATOM 1391 C5 DA D 15 6.238 23.237 43.154 1.00115.74 C ANISOU 1391 C5 DA D 15 17740 14092 12142 1508 7364 928 C ATOM 1392 C6 DA D 15 7.286 22.772 43.977 1.00113.95 C ANISOU 1392 C6 DA D 15 18193 13798 11303 1503 6978 865 C ATOM 1393 N6 DA D 15 7.877 23.523 44.911 1.00116.49 N ANISOU 1393 N6 DA D 15 18834 14213 11212 1774 6974 363 N ATOM 1394 N1 DA D 15 7.701 21.501 43.804 1.00111.72 N ANISOU 1394 N1 DA D 15 18250 13346 10855 1206 6587 1337 N ATOM 1395 C2 DA D 15 7.110 20.748 42.868 1.00112.14 C ANISOU 1395 C2 DA D 15 18003 13289 11316 910 6586 1796 C ATOM 1396 N3 DA D 15 6.121 21.071 42.035 1.00112.46 N ANISOU 1396 N3 DA D 15 17406 13421 11905 839 6927 1896 N ATOM 1397 C4 DA D 15 5.727 22.342 42.231 1.00114.05 C ANISOU 1397 C4 DA D 15 17259 13807 12268 1163 7309 1462 C ATOM 1398 P DG D 16 0.260 20.719 39.334 1.00125.26 P ANISOU 1398 P DG D 16 16150 16407 15036 -284 7528 2869 P ATOM 1399 OP1 DG D 16 -0.459 20.334 38.097 1.00118.15 O ANISOU 1399 OP1 DG D 16 14749 15580 14563 -602 7175 3054 O ATOM 1400 OP2 DG D 16 -0.414 21.568 40.351 1.00122.66 O ANISOU 1400 OP2 DG D 16 15686 16515 14403 -46 8014 2630 O ATOM 1401 O5' DG D 16 0.773 19.403 40.085 1.00122.17 O ANISOU 1401 O5' DG D 16 16442 15935 14043 -613 7421 3188 O ATOM 1402 C5' DG D 16 1.957 18.744 39.629 1.00108.21 C ANISOU 1402 C5' DG D 16 15122 13620 12373 -642 7037 3283 C ATOM 1403 C4' DG D 16 2.528 17.849 40.713 1.00110.04 C ANISOU 1403 C4' DG D 16 16106 13779 11927 -790 7000 3503 C ATOM 1404 O4' DG D 16 3.437 18.611 41.554 1.00110.98 O ANISOU 1404 O4' DG D 16 16684 13796 11686 -357 7222 3181 O ATOM 1405 C3' DG D 16 1.491 17.236 41.658 1.00117.40 C ANISOU 1405 C3' DG D 16 17035 15255 12317 -1169 7190 3797 C ATOM 1406 O3' DG D 16 1.826 15.884 41.915 1.00119.08 O ANISOU 1406 O3' DG D 16 17738 15274 12231 -1546 6835 4208 O ATOM 1407 C2' DG D 16 1.618 18.093 42.918 1.00121.78 C ANISOU 1407 C2' DG D 16 17811 16116 12342 -832 7638 3501 C ATOM 1408 C1' DG D 16 3.106 18.394 42.911 1.00121.11 C ANISOU 1408 C1' DG D 16 18284 15494 12237 -458 7470 3257 C ATOM 1409 N9 DG D 16 3.484 19.577 43.691 1.00121.38 N ANISOU 1409 N9 DG D 16 18453 15675 11989 9 7817 2753 N ATOM 1410 C8 DG D 16 3.045 20.869 43.514 1.00119.26 C ANISOU 1410 C8 DG D 16 17670 15566 12077 365 8136 2308 C ATOM 1411 N7 DG D 16 3.564 21.716 44.363 1.00121.30 N ANISOU 1411 N7 DG D 16 18209 15901 11978 741 8330 1830 N ATOM 1412 C5 DG D 16 4.404 20.938 45.151 1.00122.89 C ANISOU 1412 C5 DG D 16 19158 16040 11493 616 8128 1992 C ATOM 1413 C6 DG D 16 5.236 21.304 46.239 1.00125.80 C ANISOU 1413 C6 DG D 16 20062 16495 11242 846 8060 1616 C ATOM 1414 O6 DG D 16 5.401 22.429 46.736 1.00127.65 O ANISOU 1414 O6 DG D 16 20253 16855 11394 1217 8251 1019 O ATOM 1415 N1 DG D 16 5.920 20.202 46.757 1.00126.93 N ANISOU 1415 N1 DG D 16 20818 16552 10859 588 7655 1987 N ATOM 1416 C2 DG D 16 5.810 18.913 46.282 1.00125.66 C ANISOU 1416 C2 DG D 16 20791 16176 10777 184 7402 2627 C ATOM 1417 N2 DG D 16 6.543 17.982 46.907 1.00127.62 N ANISOU 1417 N2 DG D 16 21662 16317 10509 15 7005 2930 N ATOM 1418 N3 DG D 16 5.036 18.560 45.266 1.00123.04 N ANISOU 1418 N3 DG D 16 19980 15740 11031 -48 7462 2928 N ATOM 1419 C4 DG D 16 4.366 19.619 44.750 1.00121.70 C ANISOU 1419 C4 DG D 16 19162 15718 11360 178 7806 2586 C ATOM 1420 P DC D 17 0.781 14.911 42.651 1.00138.92 P ANISOU 1420 P DC D 17 20220 18294 14269 -2094 6868 4671 P ATOM 1421 OP1 DC D 17 0.823 13.620 41.929 1.00134.93 O ANISOU 1421 OP1 DC D 17 19804 17459 14006 -2513 6357 5049 O ATOM 1422 OP2 DC D 17 -0.505 15.633 42.792 1.00139.32 O ANISOU 1422 OP2 DC D 17 19642 19005 14289 -2137 7284 4551 O ATOM 1423 O5' DC D 17 1.409 14.713 44.113 1.00133.79 O ANISOU 1423 O5' DC D 17 20231 17739 12864 -2018 6970 4759 O ATOM 1424 C5' DC D 17 2.783 14.362 44.246 1.00129.83 C ANISOU 1424 C5' DC D 17 20409 16663 12258 -1822 6626 4747 C ATOM 1425 C4' DC D 17 3.217 14.359 45.702 1.00135.01 C ANISOU 1425 C4' DC D 17 21597 17581 12121 -1748 6742 4778 C ATOM 1426 O4' DC D 17 3.588 15.705 46.118 1.00135.98 O ANISOU 1426 O4' DC D 17 21739 17864 12065 -1252 7116 4220 O ATOM 1427 C3' DC D 17 2.155 13.892 46.707 1.00142.72 C ANISOU 1427 C3' DC D 17 22412 19266 12550 -2159 6972 5144 C ATOM 1428 O3' DC D 17 2.768 13.057 47.681 1.00147.17 O ANISOU 1428 O3' DC D 17 23567 19800 12552 -2307 6700 5489 O ATOM 1429 C2' DC D 17 1.695 15.207 47.328 1.00145.14 C ANISOU 1429 C2' DC D 17 22417 20150 12578 -1846 7553 4662 C ATOM 1430 C1' DC D 17 3.018 15.932 47.383 1.00141.61 C ANISOU 1430 C1' DC D 17 22439 19261 12105 -1329 7476 4205 C ATOM 1431 N1 DC D 17 2.915 17.393 47.633 1.00141.19 N ANISOU 1431 N1 DC D 17 22128 19485 12033 -865 7941 3570 N ATOM 1432 C2 DC D 17 3.749 17.973 48.591 1.00143.56 C ANISOU 1432 C2 DC D 17 22886 19881 11778 -549 8000 3189 C ATOM 1433 O2 DC D 17 4.552 17.252 49.194 1.00145.69 O ANISOU 1433 O2 DC D 17 23753 20032 11572 -669 7654 3430 O ATOM 1434 N3 DC D 17 3.660 19.306 48.825 1.00143.50 N ANISOU 1434 N3 DC D 17 22636 20091 11798 -121 8375 2547 N ATOM 1435 C4 DC D 17 2.777 20.042 48.147 1.00142.18 C ANISOU 1435 C4 DC D 17 21794 20020 12208 17 8680 2333 C ATOM 1436 N4 DC D 17 2.724 21.354 48.411 1.00143.35 N ANISOU 1436 N4 DC D 17 21715 20318 12433 462 8985 1683 N ATOM 1437 C5 DC D 17 1.911 19.465 47.167 1.00140.00 C ANISOU 1437 C5 DC D 17 21031 19688 12473 -305 8616 2760 C ATOM 1438 C6 DC D 17 2.012 18.148 46.946 1.00139.41 C ANISOU 1438 C6 DC D 17 21210 19423 12338 -751 8246 3347 C ATOM 1439 P DA D 18 1.881 12.178 48.695 1.00161.67 P ANISOU 1439 P DA D 18 25320 22271 13835 -2799 6768 6082 P ATOM 1440 OP1 DA D 18 1.624 10.890 48.015 1.00159.02 O ANISOU 1440 OP1 DA D 18 24931 21562 13928 -3178 6350 6637 O ATOM 1441 OP2 DA D 18 0.742 12.981 49.197 1.00163.61 O ANISOU 1441 OP2 DA D 18 25018 23364 13781 -2832 7343 5901 O ATOM 1442 O5' DA D 18 2.860 11.944 49.943 1.00165.86 O ANISOU 1442 O5' DA D 18 26511 22845 13664 -2694 6599 6171 O ATOM 1443 C5' DA D 18 4.024 12.763 50.095 1.00161.27 C ANISOU 1443 C5' DA D 18 26345 21983 12947 -2217 6552 5642 C ATOM 1444 C4' DA D 18 4.019 13.490 51.431 1.00165.55 C ANISOU 1444 C4' DA D 18 26973 23237 12690 -2083 6911 5375 C ATOM 1445 O4' DA D 18 3.817 14.913 51.218 1.00164.79 O ANISOU 1445 O4' DA D 18 26558 23328 12728 -1679 7381 4669 O ATOM 1446 C3' DA D 18 2.930 13.049 52.420 1.00173.10 C ANISOU 1446 C3' DA D 18 27635 25044 13091 -2488 7186 5806 C ATOM 1447 O3' DA D 18 3.516 12.755 53.679 1.00180.11 O ANISOU 1447 O3' DA D 18 28944 26261 13229 -2518 7050 5980 O ATOM 1448 C2' DA D 18 2.003 14.267 52.511 1.00174.65 C ANISOU 1448 C2' DA D 18 27259 25869 13230 -2312 7820 5274 C ATOM 1449 C1' DA D 18 2.978 15.398 52.236 1.00169.91 C ANISOU 1449 C1' DA D 18 26899 24856 12804 -1750 7859 4536 C ATOM 1450 N9 DA D 18 2.365 16.667 51.803 1.00168.37 N ANISOU 1450 N9 DA D 18 26173 24840 12961 -1412 8345 3924 N ATOM 1451 C8 DA D 18 2.793 17.926 52.131 1.00166.82 C ANISOU 1451 C8 DA D 18 26003 24724 12656 -919 8598 3191 C ATOM 1452 N7 DA D 18 2.072 18.892 51.610 1.00164.01 N ANISOU 1452 N7 DA D 18 25081 24472 12766 -661 8980 2769 N ATOM 1453 C5 DA D 18 1.098 18.227 50.884 1.00164.63 C ANISOU 1453 C5 DA D 18 24722 24589 13243 -1029 8979 3259 C ATOM 1454 C6 DA D 18 0.023 18.690 50.096 1.00161.87 C ANISOU 1454 C6 DA D 18 23668 24375 13461 -1007 9240 3168 C ATOM 1455 N6 DA D 18 -0.249 19.987 49.911 1.00160.39 N ANISOU 1455 N6 DA D 18 23085 24262 13596 -545 9575 2550 N ATOM 1456 N1 DA D 18 -0.765 17.766 49.506 1.00162.76 N ANISOU 1456 N1 DA D 18 23488 24542 13811 -1487 9088 3733 N ATOM 1457 C2 DA D 18 -0.492 16.469 49.696 1.00165.16 C ANISOU 1457 C2 DA D 18 24177 24723 13854 -1932 8709 4347 C ATOM 1458 N3 DA D 18 0.488 15.911 50.409 1.00166.40 N ANISOU 1458 N3 DA D 18 24990 24699 13536 -1964 8435 4526 N ATOM 1459 C4 DA D 18 1.257 16.852 50.987 1.00166.96 C ANISOU 1459 C4 DA D 18 25344 24770 13324 -1506 8589 3956 C TER 1460 DA D 18 ATOM 1461 O5' DT E 19 6.237 27.189 56.881 1.00177.92 O ANISOU 1461 O5' DT E 19 25164 28701 13736 -614 5755 669 O ATOM 1462 C5' DT E 19 5.308 26.692 55.927 1.00175.65 C ANISOU 1462 C5' DT E 19 25102 27553 14084 -1013 6132 972 C ATOM 1463 C4' DT E 19 5.286 25.173 55.931 1.00182.05 C ANISOU 1463 C4' DT E 19 26605 27954 14612 -835 6334 1907 C ATOM 1464 O4' DT E 19 4.104 24.717 55.251 1.00180.19 O ANISOU 1464 O4' DT E 19 26577 26993 14894 -1302 6811 2138 O ATOM 1465 C3' DT E 19 6.456 24.508 55.205 1.00182.59 C ANISOU 1465 C3' DT E 19 26840 27638 14900 -429 5969 2273 C ATOM 1466 O3' DT E 19 7.425 24.039 56.153 1.00191.42 O ANISOU 1466 O3' DT E 19 28184 29354 15194 121 5705 2620 O ATOM 1467 C2' DT E 19 5.817 23.341 54.421 1.00180.09 C ANISOU 1467 C2' DT E 19 26997 26431 14998 -632 6346 2916 C ATOM 1468 C1' DT E 19 4.332 23.418 54.780 1.00180.71 C ANISOU 1468 C1' DT E 19 27151 26461 15051 -1133 6899 2877 C ATOM 1469 N1 DT E 19 3.409 23.165 53.622 1.00173.38 N ANISOU 1469 N1 DT E 19 26176 24691 15008 -1578 7144 2877 N ATOM 1470 C2 DT E 19 3.115 21.867 53.261 1.00176.65 C ANISOU 1470 C2 DT E 19 26892 24493 15732 -1570 7193 3471 C ATOM 1471 O2 DT E 19 3.577 20.893 53.828 1.00183.49 O ANISOU 1471 O2 DT E 19 28141 25414 16162 -1256 7159 4057 O ATOM 1472 N3 DT E 19 2.256 21.748 52.197 1.00170.56 N ANISOU 1472 N3 DT E 19 25913 23055 15836 -1931 7250 3310 N ATOM 1473 C4 DT E 19 1.672 22.777 51.478 1.00162.78 C ANISOU 1473 C4 DT E 19 24453 21959 15437 -2260 7233 2689 C ATOM 1474 O4 DT E 19 0.911 22.570 50.537 1.00159.63 O ANISOU 1474 O4 DT E 19 23884 21001 15767 -2502 7222 2585 O ATOM 1475 C5 DT E 19 2.019 24.110 51.911 1.00157.71 C ANISOU 1475 C5 DT E 19 23489 21932 14500 -2270 7189 2130 C ATOM 1476 C7 DT E 19 1.449 25.305 51.207 1.00148.53 C ANISOU 1476 C7 DT E 19 21744 20683 14009 -2588 7128 1450 C ATOM 1477 C6 DT E 19 2.859 24.238 52.951 1.00163.69 C ANISOU 1477 C6 DT E 19 24448 23351 14393 -1956 7160 2211 C ATOM 1478 P DG E 20 8.512 25.050 56.775 1.00217.01 P ANISOU 1478 P DG E 20 30935 33463 18055 480 5175 1993 P ATOM 1479 OP1 DG E 20 8.280 25.107 58.236 1.00221.68 O ANISOU 1479 OP1 DG E 20 31608 34942 17679 618 5289 2023 O ATOM 1480 OP2 DG E 20 8.486 26.291 55.969 1.00210.07 O ANISOU 1480 OP2 DG E 20 29430 32416 17970 189 5013 1172 O ATOM 1481 O5' DG E 20 9.920 24.344 56.497 1.00194.43 O ANISOU 1481 O5' DG E 20 28275 30514 15086 1048 4739 2410 O ATOM 1482 C5' DG E 20 10.101 22.973 56.798 1.00199.51 C ANISOU 1482 C5' DG E 20 29545 30989 15272 1353 4877 3322 C ATOM 1483 C4' DG E 20 10.338 22.182 55.528 1.00195.81 C ANISOU 1483 C4' DG E 20 29318 29555 15525 1338 4874 3734 C ATOM 1484 O4' DG E 20 9.155 22.223 54.713 1.00190.85 O ANISOU 1484 O4' DG E 20 28682 28234 15597 767 5286 3642 O ATOM 1485 C3' DG E 20 11.458 22.720 54.636 1.00192.04 C ANISOU 1485 C3' DG E 20 28458 28922 15587 1537 4350 3315 C ATOM 1486 O3' DG E 20 12.673 21.944 54.820 1.00197.39 O ANISOU 1486 O3' DG E 20 29405 29715 15881 2116 4015 3805 O ATOM 1487 C2' DG E 20 10.895 22.652 53.198 1.00184.11 C ANISOU 1487 C2' DG E 20 27402 26970 15583 1125 4533 3259 C ATOM 1488 C1' DG E 20 9.529 21.987 53.383 1.00185.34 C ANISOU 1488 C1' DG E 20 27943 26786 15691 734 5139 3670 C ATOM 1489 N9 DG E 20 8.478 22.502 52.504 1.00178.02 N ANISOU 1489 N9 DG E 20 26766 25358 15516 171 5421 3281 N ATOM 1490 C8 DG E 20 8.253 23.811 52.148 1.00171.43 C ANISOU 1490 C8 DG E 20 25343 24679 15114 -98 5312 2502 C ATOM 1491 N7 DG E 20 7.226 23.964 51.353 1.00165.97 N ANISOU 1491 N7 DG E 20 24551 23463 15047 -573 5638 2353 N ATOM 1492 C5 DG E 20 6.739 22.672 51.171 1.00168.23 C ANISOU 1492 C5 DG E 20 25385 23210 15324 -639 5981 3037 C ATOM 1493 C6 DG E 20 5.635 22.203 50.407 1.00162.52 C ANISOU 1493 C6 DG E 20 24801 21813 15136 -1075 6416 3181 C ATOM 1494 O6 DG E 20 4.841 22.860 49.714 1.00154.74 O ANISOU 1494 O6 DG E 20 23479 20596 14720 -1488 6577 2743 O ATOM 1495 N1 DG E 20 5.495 20.817 50.502 1.00165.31 N ANISOU 1495 N1 DG E 20 25721 21754 15336 -987 6674 3911 N ATOM 1496 C2 DG E 20 6.315 19.994 51.241 1.00171.76 C ANISOU 1496 C2 DG E 20 26927 22779 15554 -521 6539 4476 C ATOM 1497 N2 DG E 20 6.027 18.688 51.215 1.00173.78 N ANISOU 1497 N2 DG E 20 27442 22571 16016 -525 6589 4987 N ATOM 1498 N3 DG E 20 7.346 20.421 51.957 1.00177.44 N ANISOU 1498 N3 DG E 20 27547 24161 15710 -90 6142 4384 N ATOM 1499 C4 DG E 20 7.498 21.764 51.877 1.00175.57 C ANISOU 1499 C4 DG E 20 26744 24336 15628 -186 5866 3625 C ATOM 1500 P DC E 21 12.963 20.568 54.027 1.00199.97 P ANISOU 1500 P DC E 21 30246 29206 16527 2273 4101 4604 P ATOM 1501 OP1 DC E 21 13.933 19.815 54.853 1.00206.37 O ANISOU 1501 OP1 DC E 21 31375 30463 16572 2878 3884 5162 O ATOM 1502 OP2 DC E 21 13.309 20.884 52.621 1.00187.86 O ANISOU 1502 OP2 DC E 21 28432 27028 15917 2135 3885 4274 O ATOM 1503 O5' DC E 21 11.581 19.759 54.072 1.00185.08 O ANISOU 1503 O5' DC E 21 28795 26822 14704 1872 4760 5112 O ATOM 1504 C5' DC E 21 11.582 18.333 54.106 1.00185.34 C ANISOU 1504 C5' DC E 21 29419 26396 14605 2059 5021 6001 C ATOM 1505 C4' DC E 21 11.401 17.744 52.713 1.00177.07 C ANISOU 1505 C4' DC E 21 28479 24331 14469 1824 5143 6153 C ATOM 1506 O4' DC E 21 10.388 18.479 51.983 1.00169.98 O ANISOU 1506 O4' DC E 21 27257 23113 14216 1244 5354 5586 O ATOM 1507 C3' DC E 21 12.653 17.749 51.821 1.00170.42 C ANISOU 1507 C3' DC E 21 27476 23242 14034 2142 4633 6046 C ATOM 1508 O3' DC E 21 12.978 16.406 51.456 1.00171.51 O ANISOU 1508 O3' DC E 21 28001 22764 14401 2314 4684 6700 O ATOM 1509 C2' DC E 21 12.243 18.600 50.607 1.00161.55 C ANISOU 1509 C2' DC E 21 25898 21701 13784 1705 4585 5375 C ATOM 1510 C1' DC E 21 10.733 18.460 50.624 1.00162.29 C ANISOU 1510 C1' DC E 21 26116 21499 14048 1169 5169 5413 C ATOM 1511 N1 DC E 21 10.015 19.567 49.919 1.00153.88 N ANISOU 1511 N1 DC E 21 24553 20339 13574 696 5215 4686 N ATOM 1512 C2 DC E 21 8.937 19.262 49.080 1.00148.80 C ANISOU 1512 C2 DC E 21 23958 19033 13544 227 5622 4697 C ATOM 1513 O2 DC E 21 8.595 18.080 48.945 1.00152.91 O ANISOU 1513 O2 DC E 21 24898 19044 14157 190 5915 5254 O ATOM 1514 N3 DC E 21 8.292 20.274 48.442 1.00138.13 N ANISOU 1514 N3 DC E 21 22142 17631 12712 -170 5664 4065 N ATOM 1515 C4 DC E 21 8.693 21.535 48.618 1.00132.61 C ANISOU 1515 C4 DC E 21 20948 17460 11978 -120 5342 3455 C ATOM 1516 N4 DC E 21 8.028 22.499 47.970 1.00123.24 N ANISOU 1516 N4 DC E 21 19303 16183 11341 -503 5426 2884 N ATOM 1517 C5 DC E 21 9.794 21.864 49.465 1.00138.62 C ANISOU 1517 C5 DC E 21 21639 18872 12158 335 4933 3393 C ATOM 1518 C6 DC E 21 10.420 20.859 50.088 1.00148.08 C ANISOU 1518 C6 DC E 21 23299 20161 12802 734 4872 4012 C ATOM 1519 P DT E 22 13.872 16.081 50.160 1.00169.36 P ANISOU 1519 P DT E 22 27689 21870 14791 2485 4380 6725 P ATOM 1520 OP1 DT E 22 14.425 14.726 50.374 1.00174.93 O ANISOU 1520 OP1 DT E 22 28622 22294 15549 2722 4251 7246 O ATOM 1521 OP2 DT E 22 14.798 17.202 49.870 1.00163.47 O ANISOU 1521 OP2 DT E 22 26486 21533 14092 2686 3857 6125 O ATOM 1522 O5' DT E 22 12.804 15.982 48.976 1.00159.64 O ANISOU 1522 O5' DT E 22 26352 19849 14455 1905 4711 6502 O ATOM 1523 C5' DT E 22 12.046 14.789 48.792 1.00159.84 C ANISOU 1523 C5' DT E 22 26508 19290 14932 1609 4962 6760 C ATOM 1524 C4' DT E 22 11.587 14.688 47.353 1.00153.63 C ANISOU 1524 C4' DT E 22 25520 17801 15053 1254 5028 6463 C ATOM 1525 O4' DT E 22 10.677 15.777 47.088 1.00148.60 O ANISOU 1525 O4' DT E 22 24640 17265 14557 855 5261 5987 O ATOM 1526 C3' DT E 22 12.723 14.814 46.332 1.00152.54 C ANISOU 1526 C3' DT E 22 25256 17425 15275 1537 4636 6363 C ATOM 1527 O3' DT E 22 12.990 13.564 45.617 1.00156.19 O ANISOU 1527 O3' DT E 22 25757 17309 16280 1554 4533 6545 O ATOM 1528 C2' DT E 22 12.317 15.954 45.399 1.00143.39 C ANISOU 1528 C2' DT E 22 23779 16167 14538 1254 4704 5844 C ATOM 1529 C1' DT E 22 10.875 16.265 45.787 1.00142.74 C ANISOU 1529 C1' DT E 22 23628 16167 14441 755 5134 5634 C ATOM 1530 N1 DT E 22 10.596 17.721 45.776 1.00139.07 N ANISOU 1530 N1 DT E 22 22786 16111 13942 569 5127 5069 N ATOM 1531 C2 DT E 22 9.442 18.183 45.193 1.00133.79 C ANISOU 1531 C2 DT E 22 21873 15221 13740 63 5434 4694 C ATOM 1532 O2 DT E 22 8.602 17.449 44.699 1.00132.19 O ANISOU 1532 O2 DT E 22 21682 14564 13983 -231 5617 4724 O ATOM 1533 N3 DT E 22 9.297 19.545 45.219 1.00127.73 N ANISOU 1533 N3 DT E 22 20599 14894 13038 -83 5277 4061 N ATOM 1534 C4 DT E 22 10.178 20.470 45.752 1.00126.64 C ANISOU 1534 C4 DT E 22 20166 15366 12586 207 4858 3735 C ATOM 1535 O4 DT E 22 9.958 21.676 45.728 1.00122.00 O ANISOU 1535 O4 DT E 22 19102 15103 12150 36 4778 3152 O ATOM 1536 C5 DT E 22 11.375 19.917 46.338 1.00133.40 C ANISOU 1536 C5 DT E 22 21292 16447 12949 729 4535 4118 C ATOM 1537 C7 DT E 22 12.406 20.820 46.946 1.00134.72 C ANISOU 1537 C7 DT E 22 21145 17292 12752 1079 4066 3765 C ATOM 1538 C6 DT E 22 11.526 18.586 46.317 1.00138.75 C ANISOU 1538 C6 DT E 22 22479 16709 13531 891 4679 4776 C ATOM 1539 P DT E 23 11.843 12.679 44.902 1.00134.09 P ANISOU 1539 P DT E 23 22881 13920 14146 1090 4829 6442 P ATOM 1540 OP1 DT E 23 10.935 12.109 45.920 1.00143.23 O ANISOU 1540 OP1 DT E 23 24247 15172 15004 921 5179 6713 O ATOM 1541 OP2 DT E 23 12.556 11.768 43.977 1.00130.79 O ANISOU 1541 OP2 DT E 23 22413 13065 14217 1228 4584 6491 O ATOM 1542 O5' DT E 23 11.027 13.688 43.975 1.00123.71 O ANISOU 1542 O5' DT E 23 21222 12499 13282 695 4944 5878 O ATOM 1543 C5' DT E 23 9.668 13.416 43.678 1.00121.65 C ANISOU 1543 C5' DT E 23 20837 11994 13390 235 5258 5660 C ATOM 1544 C4' DT E 23 9.218 14.167 42.439 1.00115.60 C ANISOU 1544 C4' DT E 23 19667 11064 13191 -39 5222 5109 C ATOM 1545 O4' DT E 23 9.377 15.588 42.641 1.00112.69 O ANISOU 1545 O4' DT E 23 19156 11070 12589 -38 5209 4876 O ATOM 1546 C3' DT E 23 9.973 13.822 41.153 1.00109.78 C ANISOU 1546 C3' DT E 23 18742 10001 12969 108 4912 4972 C ATOM 1547 O3' DT E 23 9.040 13.342 40.187 1.00107.59 O ANISOU 1547 O3' DT E 23 18222 9422 13235 -209 5014 4657 O ATOM 1548 C2' DT E 23 10.635 15.145 40.732 1.00104.77 C ANISOU 1548 C2' DT E 23 17879 9572 12358 238 4709 4714 C ATOM 1549 C1' DT E 23 9.778 16.183 41.436 1.00105.54 C ANISOU 1549 C1' DT E 23 17919 10008 12172 -25 5000 4533 C ATOM 1550 N1 DT E 23 10.500 17.441 41.772 1.00102.04 N ANISOU 1550 N1 DT E 23 17427 9934 11408 177 4925 4472 N ATOM 1551 C2 DT E 23 9.898 18.647 41.514 1.00101.46 C ANISOU 1551 C2 DT E 23 16957 10065 11530 -114 5033 3982 C ATOM 1552 O2 DT E 23 8.799 18.750 41.000 1.00104.08 O ANISOU 1552 O2 DT E 23 17057 10242 12248 -511 5237 3684 O ATOM 1553 N3 DT E 23 10.633 19.739 41.874 1.00 95.77 N ANISOU 1553 N3 DT E 23 15891 9878 10619 104 4651 3632 N ATOM 1554 C4 DT E 23 11.880 19.757 42.457 1.00 99.33 C ANISOU 1554 C4 DT E 23 16418 10658 10664 573 4245 3765 C ATOM 1555 O4 DT E 23 12.457 20.805 42.741 1.00101.80 O ANISOU 1555 O4 DT E 23 16360 11446 10872 724 3930 3368 O ATOM 1556 C5 DT E 23 12.458 18.458 42.709 1.00104.53 C ANISOU 1556 C5 DT E 23 17599 11060 11058 875 4229 4391 C ATOM 1557 C7 DT E 23 13.815 18.348 43.337 1.00109.82 C ANISOU 1557 C7 DT E 23 18385 12079 11262 1412 3796 4595 C ATOM 1558 C6 DT E 23 11.746 17.374 42.360 1.00104.01 C ANISOU 1558 C6 DT E 23 17881 10435 11201 666 4621 4766 C ATOM 1559 P DC E 24 9.405 13.275 38.624 1.00101.89 P ANISOU 1559 P DC E 24 17152 8478 13084 -188 4744 4311 P ATOM 1560 OP1 DC E 24 8.508 12.262 38.027 1.00102.72 O ANISOU 1560 OP1 DC E 24 17179 8308 13541 -420 4896 4183 O ATOM 1561 OP2 DC E 24 10.870 13.132 38.461 1.00100.84 O ANISOU 1561 OP2 DC E 24 17099 8327 12889 208 4393 4517 O ATOM 1562 O5' DC E 24 8.927 14.699 38.074 1.00 99.91 O ANISOU 1562 O5' DC E 24 16510 8438 13012 -378 4747 3835 O ATOM 1563 C5' DC E 24 7.576 15.107 38.280 1.00 94.99 C ANISOU 1563 C5' DC E 24 15753 7928 12412 -738 5023 3577 C ATOM 1564 C4' DC E 24 7.339 16.499 37.736 1.00 90.70 C ANISOU 1564 C4' DC E 24 14801 7608 12054 -858 4970 3139 C ATOM 1565 O4' DC E 24 8.235 17.432 38.395 1.00 91.68 O ANISOU 1565 O4' DC E 24 15011 7951 11873 -666 4924 3279 O ATOM 1566 C3' DC E 24 7.590 16.664 36.228 1.00 89.02 C ANISOU 1566 C3' DC E 24 14185 7313 12328 -794 4716 2803 C ATOM 1567 O3' DC E 24 6.532 17.427 35.641 1.00 82.10 O ANISOU 1567 O3' DC E 24 12908 6603 11683 -1039 4775 2345 O ATOM 1568 C2' DC E 24 8.922 17.412 36.178 1.00 82.00 C ANISOU 1568 C2' DC E 24 13255 6498 11404 -492 4489 2896 C ATOM 1569 C1' DC E 24 8.797 18.274 37.419 1.00 83.04 C ANISOU 1569 C1' DC E 24 13541 6878 11134 -562 4709 2999 C ATOM 1570 N1 DC E 24 10.088 18.821 37.936 1.00 84.21 N ANISOU 1570 N1 DC E 24 13850 7129 11016 -218 4587 3259 N ATOM 1571 C2 DC E 24 10.303 20.194 37.882 1.00 80.93 C ANISOU 1571 C2 DC E 24 13079 6976 10694 -220 4556 2964 C ATOM 1572 O2 DC E 24 9.423 20.912 37.392 1.00 80.46 O ANISOU 1572 O2 DC E 24 12641 6967 10963 -541 4733 2586 O ATOM 1573 N3 DC E 24 11.469 20.701 38.363 1.00 81.81 N ANISOU 1573 N3 DC E 24 13099 7440 10545 164 4139 2920 N ATOM 1574 C4 DC E 24 12.388 19.884 38.883 1.00 86.22 C ANISOU 1574 C4 DC E 24 14058 7969 10732 525 3939 3336 C ATOM 1575 N4 DC E 24 13.520 20.429 39.347 1.00 84.65 N ANISOU 1575 N4 DC E 24 13728 8155 10279 901 3521 3243 N ATOM 1576 C5 DC E 24 12.183 18.473 38.953 1.00 87.75 C ANISOU 1576 C5 DC E 24 14784 7732 10826 520 4176 3858 C ATOM 1577 C6 DC E 24 11.027 17.989 38.473 1.00 87.71 C ANISOU 1577 C6 DC E 24 14703 7499 11125 131 4430 3710 C ATOM 1578 P DT E 25 6.370 17.513 34.042 1.00 89.75 P ANISOU 1578 P DT E 25 13434 7580 13086 -1004 4571 1967 P ATOM 1579 OP1 DT E 25 4.926 17.407 33.742 1.00 78.12 O ANISOU 1579 OP1 DT E 25 11802 6173 11707 -1253 4714 1676 O ATOM 1580 OP2 DT E 25 7.370 16.630 33.391 1.00 74.47 O ANISOU 1580 OP2 DT E 25 11581 5440 11273 -766 4366 2144 O ATOM 1581 O5' DT E 25 6.741 19.028 33.721 1.00 80.24 O ANISOU 1581 O5' DT E 25 11848 6630 12009 -930 4440 1712 O ATOM 1582 C5' DT E 25 5.954 20.052 34.287 1.00 78.24 C ANISOU 1582 C5' DT E 25 11447 6614 11667 -1130 4575 1497 C ATOM 1583 C4' DT E 25 6.549 21.413 34.009 1.00 64.65 C ANISOU 1583 C4' DT E 25 9358 5088 10118 -1013 4446 1297 C ATOM 1584 O4' DT E 25 7.819 21.539 34.685 1.00 66.19 O ANISOU 1584 O4' DT E 25 9768 5205 10176 -831 4456 1614 O ATOM 1585 C3' DT E 25 6.805 21.717 32.538 1.00 59.58 C ANISOU 1585 C3' DT E 25 8298 4495 9846 -820 4192 1051 C ATOM 1586 O3' DT E 25 6.287 22.976 32.264 1.00 68.95 O ANISOU 1586 O3' DT E 25 9098 5933 11166 -851 4121 705 O ATOM 1587 C2' DT E 25 8.333 21.693 32.415 1.00 58.92 C ANISOU 1587 C2' DT E 25 8248 4284 9857 -534 4043 1291 C ATOM 1588 C1' DT E 25 8.755 22.105 33.813 1.00 62.11 C ANISOU 1588 C1' DT E 25 8922 4685 9993 -580 4224 1521 C ATOM 1589 N1 DT E 25 10.085 21.633 34.224 1.00 66.72 N ANISOU 1589 N1 DT E 25 9846 5065 10440 -288 4119 1934 N ATOM 1590 C2 DT E 25 10.979 22.548 34.688 1.00 63.69 C ANISOU 1590 C2 DT E 25 9351 4800 10048 -95 4035 1956 C ATOM 1591 O2 DT E 25 10.739 23.729 34.755 1.00 71.36 O ANISOU 1591 O2 DT E 25 9887 6075 11150 -191 4041 1593 O ATOM 1592 N3 DT E 25 12.183 22.039 35.058 1.00 68.45 N ANISOU 1592 N3 DT E 25 10230 5392 10386 298 3703 2223 N ATOM 1593 C4 DT E 25 12.582 20.729 35.038 1.00 68.66 C ANISOU 1593 C4 DT E 25 10739 5075 10272 455 3677 2657 C ATOM 1594 O4 DT E 25 13.693 20.390 35.414 1.00 70.81 O ANISOU 1594 O4 DT E 25 11219 5388 10297 829 3363 2881 O ATOM 1595 C5 DT E 25 11.598 19.793 34.547 1.00 69.24 C ANISOU 1595 C5 DT E 25 10857 5037 10413 174 3807 2582 C ATOM 1596 C7 DT E 25 11.925 18.328 34.472 1.00 72.47 C ANISOU 1596 C7 DT E 25 11593 5258 10683 289 3662 2841 C ATOM 1597 C6 DT E 25 10.399 20.283 34.168 1.00 68.18 C ANISOU 1597 C6 DT E 25 10403 5037 10465 -161 4003 2220 C HETATM 1598 N1 5CM E 26 11.727 23.577 30.968 1.00 54.02 N ANISOU 1598 N1 5CM E 26 6776 3756 9993 293 3387 1278 N HETATM 1599 C2 5CM E 26 12.867 23.669 31.912 1.00 56.44 C ANISOU 1599 C2 5CM E 26 7365 3880 10198 538 3273 1548 C HETATM 1600 N3 5CM E 26 13.637 22.448 32.237 1.00 60.44 N ANISOU 1600 N3 5CM E 26 8382 4217 10367 758 3066 1904 N HETATM 1601 C4 5CM E 26 13.295 21.175 31.659 1.00 57.03 C ANISOU 1601 C4 5CM E 26 8136 3730 9802 648 3020 1965 C HETATM 1602 C5 5CM E 26 12.158 21.081 30.714 1.00 57.59 C ANISOU 1602 C5 5CM E 26 7916 3922 10044 383 3167 1681 C HETATM 1603 C5A 5CM E 26 11.788 19.739 30.094 1.00 55.91 C ANISOU 1603 C5A 5CM E 26 7870 3611 9763 301 3138 1713 C HETATM 1604 C6 5CM E 26 11.368 22.300 30.376 1.00 56.68 C ANISOU 1604 C6 5CM E 26 7327 4032 10175 242 3334 1347 C HETATM 1605 O2 5CM E 26 13.158 24.714 32.396 1.00 60.53 O ANISOU 1605 O2 5CM E 26 7631 4588 10781 606 3228 1368 O HETATM 1606 N4 5CM E 26 14.082 20.014 32.007 1.00 60.51 N ANISOU 1606 N4 5CM E 26 9017 4012 9963 843 2815 2283 N HETATM 1607 C1' 5CM E 26 11.004 24.807 30.676 1.00 47.38 C ANISOU 1607 C1' 5CM E 26 5454 3143 9406 191 3501 912 C HETATM 1608 C2' 5CM E 26 10.122 24.769 29.376 1.00 44.10 C ANISOU 1608 C2' 5CM E 26 4781 2885 9091 230 3411 633 C HETATM 1609 C3' 5CM E 26 9.216 25.961 29.654 1.00 58.38 C ANISOU 1609 C3' 5CM E 26 6528 4750 10904 109 3365 329 C HETATM 1610 C4' 5CM E 26 8.996 25.961 30.982 1.00 58.76 C ANISOU 1610 C4' 5CM E 26 6776 4833 10719 -151 3599 410 C HETATM 1611 O4' 5CM E 26 10.137 25.005 31.613 1.00 55.76 O ANISOU 1611 O4' 5CM E 26 6705 4231 10248 -83 3727 848 O HETATM 1612 O3' 5CM E 26 10.064 27.128 29.396 1.00 51.94 O ANISOU 1612 O3' 5CM E 26 5519 4046 10171 166 2967 290 O HETATM 1613 C5' 5CM E 26 7.648 25.411 31.326 1.00 58.58 C ANISOU 1613 C5' 5CM E 26 7005 4863 10390 -437 3742 356 C HETATM 1614 O5' 5CM E 26 7.321 24.405 30.417 1.00 56.23 O ANISOU 1614 O5' 5CM E 26 6783 4480 10102 -380 3701 393 O HETATM 1615 P 5CM E 26 6.035 23.446 30.755 1.00 56.68 P ANISOU 1615 P 5CM E 26 7137 4500 9897 -662 3875 405 P HETATM 1616 OP1 5CM E 26 4.782 24.293 30.774 1.00 71.04 O ANISOU 1616 OP1 5CM E 26 8820 6517 11655 -801 3826 116 O HETATM 1617 OP2 5CM E 26 5.988 22.268 29.806 1.00 61.90 O ANISOU 1617 OP2 5CM E 26 7855 5038 10626 -587 3848 462 O ATOM 1618 P DG E 27 9.468 28.476 28.782 1.00 42.95 P ANISOU 1618 P DG E 27 5447 3622 7251 -186 110 1193 P ATOM 1619 OP1 DG E 27 8.195 28.779 29.469 1.00 53.66 O ANISOU 1619 OP1 DG E 27 6538 5035 8814 -106 129 1288 O ATOM 1620 OP2 DG E 27 9.509 28.401 27.301 1.00 41.68 O ANISOU 1620 OP2 DG E 27 5353 3434 7048 -607 -117 1023 O ATOM 1621 O5' DG E 27 10.586 29.556 29.172 1.00 42.67 O ANISOU 1621 O5' DG E 27 5468 3752 6992 141 -104 1176 O ATOM 1622 C5' DG E 27 11.017 29.633 30.515 1.00 31.48 C ANISOU 1622 C5' DG E 27 4051 2425 5485 632 54 1245 C ATOM 1623 C4' DG E 27 12.363 30.322 30.628 1.00 33.21 C ANISOU 1623 C4' DG E 27 4330 2735 5554 867 -126 1109 C ATOM 1624 O4' DG E 27 13.396 29.337 30.830 1.00 34.83 O ANISOU 1624 O4' DG E 27 4750 2853 5632 1019 145 1095 O ATOM 1625 C3' DG E 27 12.829 31.130 29.419 1.00 35.87 C ANISOU 1625 C3' DG E 27 4665 3045 5919 551 -430 998 C ATOM 1626 O3' DG E 27 13.806 32.098 29.884 1.00 40.15 O ANISOU 1626 O3' DG E 27 5119 3668 6470 843 -608 860 O ATOM 1627 C2' DG E 27 13.485 30.027 28.566 1.00 34.58 C ANISOU 1627 C2' DG E 27 4740 2731 5666 293 -214 960 C ATOM 1628 C1' DG E 27 14.170 29.179 29.644 1.00 29.18 C ANISOU 1628 C1' DG E 27 4160 2023 4903 687 88 975 C ATOM 1629 N9 DG E 27 14.207 27.744 29.362 1.00 40.19 N ANISOU 1629 N9 DG E 27 5742 3221 6306 540 432 1020 N ATOM 1630 C8 DG E 27 13.251 27.002 28.718 1.00 33.56 C ANISOU 1630 C8 DG E 27 4910 2230 5610 168 555 1054 C ATOM 1631 N7 DG E 27 13.540 25.731 28.650 1.00 39.13 N ANISOU 1631 N7 DG E 27 5773 2719 6376 124 891 1057 N ATOM 1632 C5 DG E 27 14.745 25.614 29.322 1.00 42.42 C ANISOU 1632 C5 DG E 27 6310 3170 6638 521 992 1063 C ATOM 1633 C6 DG E 27 15.546 24.475 29.570 1.00 49.20 C ANISOU 1633 C6 DG E 27 7297 3973 7423 660 1253 1026 C ATOM 1634 O6 DG E 27 15.328 23.282 29.259 1.00 47.32 O ANISOU 1634 O6 DG E 27 7117 3555 7309 474 1510 1016 O ATOM 1635 N1 DG E 27 16.696 24.809 30.271 1.00 46.14 N ANISOU 1635 N1 DG E 27 6918 3780 6834 1062 1167 962 N ATOM 1636 C2 DG E 27 17.026 26.078 30.685 1.00 43.59 C ANISOU 1636 C2 DG E 27 6460 3687 6416 1281 854 875 C ATOM 1637 N2 DG E 27 18.186 26.208 31.350 1.00 38.32 N ANISOU 1637 N2 DG E 27 5739 3228 5592 1593 750 717 N ATOM 1638 N3 DG E 27 16.298 27.144 30.441 1.00 42.43 N ANISOU 1638 N3 DG E 27 6192 3567 6363 1166 627 903 N ATOM 1639 C4 DG E 27 15.171 26.844 29.767 1.00 44.46 C ANISOU 1639 C4 DG E 27 6455 3667 6772 781 699 1013 C HETATM 1640 N1 5CM E 28 17.827 28.503 27.578 1.00 36.86 N ANISOU 1640 N1 5CM E 28 5502 2783 5718 394 241 543 N HETATM 1641 C2 5CM E 28 18.553 27.232 27.784 1.00 37.28 C ANISOU 1641 C2 5CM E 28 5723 2711 5730 530 543 487 C HETATM 1642 N3 5CM E 28 17.979 25.976 27.250 1.00 39.13 N ANISOU 1642 N3 5CM E 28 6122 2764 5980 262 793 533 N HETATM 1643 C4 5CM E 28 16.725 26.005 26.542 1.00 39.13 C ANISOU 1643 C4 5CM E 28 6092 2753 6023 -122 705 584 C HETATM 1644 C5 5CM E 28 15.996 27.285 26.334 1.00 38.88 C ANISOU 1644 C5 5CM E 28 5897 2897 5978 -228 369 648 C HETATM 1645 C5A 5CM E 28 14.673 27.318 25.579 1.00 38.86 C ANISOU 1645 C5A 5CM E 28 5835 2916 6014 -584 224 670 C HETATM 1646 C6 5CM E 28 16.565 28.521 26.876 1.00 28.73 C ANISOU 1646 C6 5CM E 28 4476 1748 4692 37 160 652 C HETATM 1647 O2 5CM E 28 19.577 27.243 28.370 1.00 42.19 O ANISOU 1647 O2 5CM E 28 6319 3364 6346 862 567 377 O HETATM 1648 N4 5CM E 28 16.175 24.794 26.025 1.00 33.22 N ANISOU 1648 N4 5CM E 28 5439 1808 5375 -388 924 534 N HETATM 1649 C1' 5CM E 28 18.382 29.744 28.106 1.00 27.42 C ANISOU 1649 C1' 5CM E 28 4106 1701 4611 645 7 450 C HETATM 1650 C2' 5CM E 28 18.487 30.883 27.014 1.00 38.97 C ANISOU 1650 C2' 5CM E 28 5491 3152 6164 315 -189 448 C HETATM 1651 C3' 5CM E 28 18.279 32.161 27.804 1.00 26.80 C ANISOU 1651 C3' 5CM E 28 3687 1688 4808 562 -456 416 C HETATM 1652 C4' 5CM E 28 17.920 31.775 29.049 1.00 26.74 C ANISOU 1652 C4' 5CM E 28 3636 1785 4739 940 -434 401 C HETATM 1653 O4' 5CM E 28 17.514 30.226 28.930 1.00 27.24 O ANISOU 1653 O4' 5CM E 28 3951 1783 4618 841 -125 536 O HETATM 1654 O3' 5CM E 28 19.589 32.838 27.933 1.00 27.09 O ANISOU 1654 O3' 5CM E 28 3563 1678 5052 713 -501 193 O HETATM 1655 C5' 5CM E 28 16.733 32.489 29.584 1.00 27.95 C ANISOU 1655 C5' 5CM E 28 3634 2058 4928 1015 -614 492 C HETATM 1656 O5' 5CM E 28 15.875 32.748 28.525 1.00 33.62 O ANISOU 1656 O5' 5CM E 28 4385 2696 5693 606 -711 662 O HETATM 1657 P 5CM E 28 14.387 33.263 28.936 1.00 29.83 P ANISOU 1657 P 5CM E 28 3744 2305 5284 633 -882 787 P HETATM 1658 OP1 5CM E 28 14.500 34.514 29.799 1.00 39.63 O ANISOU 1658 OP1 5CM E 28 4756 3762 6538 872 -1006 591 O HETATM 1659 OP2 5CM E 28 13.537 33.502 27.713 1.00 30.78 O ANISOU 1659 OP2 5CM E 28 3897 2386 5413 215 -1021 930 O ATOM 1660 P DG E 29 20.338 33.425 26.646 1.00 30.53 P ANISOU 1660 P DG E 29 4006 1969 5626 360 -441 210 P ATOM 1661 OP1 DG E 29 21.001 34.694 27.073 1.00 28.64 O ANISOU 1661 OP1 DG E 29 3444 1650 5787 527 -601 29 O ATOM 1662 OP2 DG E 29 19.446 33.355 25.453 1.00 28.30 O ANISOU 1662 OP2 DG E 29 3923 1687 5144 -38 -430 480 O ATOM 1663 O5' DG E 29 21.518 32.371 26.442 1.00 37.47 O ANISOU 1663 O5' DG E 29 5013 2808 6418 382 -166 43 O ATOM 1664 C5' DG E 29 22.274 32.002 27.554 1.00 32.85 C ANISOU 1664 C5' DG E 29 4312 2274 5897 808 -165 -207 C ATOM 1665 C4' DG E 29 23.343 31.034 27.167 1.00 29.09 C ANISOU 1665 C4' DG E 29 3957 1733 5363 788 93 -342 C ATOM 1666 O4' DG E 29 22.743 29.776 26.774 1.00 28.87 O ANISOU 1666 O4' DG E 29 4236 1689 5045 629 291 -176 O ATOM 1667 C3' DG E 29 24.179 31.471 26.004 1.00 30.20 C ANISOU 1667 C3' DG E 29 4064 1748 5663 457 240 -385 C ATOM 1668 O3' DG E 29 25.464 30.960 26.194 1.00 34.25 O ANISOU 1668 O3' DG E 29 4496 2222 6296 638 388 -662 O ATOM 1669 C2' DG E 29 23.484 30.830 24.804 1.00 39.44 C ANISOU 1669 C2' DG E 29 5555 2914 6517 49 404 -144 C ATOM 1670 C1' DG E 29 22.989 29.510 25.394 1.00 32.10 C ANISOU 1670 C1' DG E 29 4806 2019 5373 210 476 -139 C ATOM 1671 N9 DG E 29 21.723 29.032 24.845 1.00 29.51 N ANISOU 1671 N9 DG E 29 4677 1711 4823 -62 475 61 N ATOM 1672 C8 DG E 29 20.675 29.805 24.406 1.00 39.09 C ANISOU 1672 C8 DG E 29 5871 2989 5990 -273 278 249 C ATOM 1673 N7 DG E 29 19.633 29.105 24.037 1.00 34.64 N ANISOU 1673 N7 DG E 29 5453 2445 5264 -464 286 335 N ATOM 1674 C5 DG E 29 19.995 27.787 24.277 1.00 30.17 C ANISOU 1674 C5 DG E 29 5013 1781 4670 -386 533 215 C ATOM 1675 C6 DG E 29 19.265 26.596 24.072 1.00 43.63 C ANISOU 1675 C6 DG E 29 6858 3399 6322 -533 673 203 C ATOM 1676 O6 DG E 29 18.111 26.466 23.625 1.00 42.44 O ANISOU 1676 O6 DG E 29 6720 3273 6131 -771 577 256 O ATOM 1677 N1 DG E 29 20.003 25.468 24.437 1.00 35.08 N ANISOU 1677 N1 DG E 29 5872 2164 5293 -368 947 89 N ATOM 1678 C2 DG E 29 21.275 25.488 24.949 1.00 41.80 C ANISOU 1678 C2 DG E 29 6686 2997 6199 -68 1035 -13 C ATOM 1679 N2 DG E 29 21.803 24.287 25.251 1.00 32.73 N ANISOU 1679 N2 DG E 29 5649 1685 5100 96 1293 -94 N ATOM 1680 N3 DG E 29 21.985 26.606 25.144 1.00 30.65 N ANISOU 1680 N3 DG E 29 5108 1694 4845 68 878 -57 N ATOM 1681 C4 DG E 29 21.273 27.717 24.797 1.00 35.32 C ANISOU 1681 C4 DG E 29 5608 2390 5424 -115 647 70 C ATOM 1682 P DA E 30 26.710 31.612 25.442 1.00 33.46 P ANISOU 1682 P DA E 30 4191 1991 6532 454 549 -830 P ATOM 1683 OP1 DA E 30 27.880 31.358 26.314 1.00 45.62 O ANISOU 1683 OP1 DA E 30 5511 3761 8062 768 466 -1106 O ATOM 1684 OP2 DA E 30 26.301 32.965 25.027 1.00 46.90 O ANISOU 1684 OP2 DA E 30 5751 3598 8470 237 448 -665 O ATOM 1685 O5' DA E 30 26.883 30.701 24.142 1.00 33.90 O ANISOU 1685 O5' DA E 30 4561 2005 6314 99 896 -710 O ATOM 1686 C5' DA E 30 27.127 29.326 24.316 1.00 36.48 C ANISOU 1686 C5' DA E 30 5071 2354 6434 233 1037 -823 C ATOM 1687 C4' DA E 30 26.909 28.563 23.027 1.00 34.75 C ANISOU 1687 C4' DA E 30 5167 2127 5911 -142 1300 -708 C ATOM 1688 O4' DA E 30 25.481 28.282 22.852 1.00 44.26 O ANISOU 1688 O4' DA E 30 6597 3398 6821 -298 1176 -468 O ATOM 1689 C3' DA E 30 27.341 29.302 21.752 1.00 38.56 C ANISOU 1689 C3' DA E 30 5649 2593 6411 -490 1496 -622 C ATOM 1690 O3' DA E 30 27.896 28.353 20.854 1.00 42.29 O ANISOU 1690 O3' DA E 30 6313 3070 6687 -647 1812 -739 O ATOM 1691 C2' DA E 30 26.011 29.832 21.219 1.00 37.91 C ANISOU 1691 C2' DA E 30 5735 2601 6070 -723 1326 -293 C ATOM 1692 C1' DA E 30 25.144 28.623 21.531 1.00 43.09 C ANISOU 1692 C1' DA E 30 6601 3307 6462 -677 1255 -315 C ATOM 1693 N9 DA E 30 23.700 28.805 21.411 1.00 49.08 N ANISOU 1693 N9 DA E 30 7470 4155 7021 -808 1027 -91 N ATOM 1694 C8 DA E 30 22.996 29.974 21.283 1.00 33.86 C ANISOU 1694 C8 DA E 30 5465 2283 5117 -885 805 142 C ATOM 1695 N7 DA E 30 21.687 29.789 21.160 1.00 33.52 N ANISOU 1695 N7 DA E 30 5528 2329 4878 -989 617 273 N ATOM 1696 C5 DA E 30 21.541 28.403 21.202 1.00 33.66 C ANISOU 1696 C5 DA E 30 5693 2322 4776 -1006 750 107 C ATOM 1697 C6 DA E 30 20.425 27.550 21.108 1.00 40.56 C ANISOU 1697 C6 DA E 30 6674 3212 5524 -1122 689 90 C ATOM 1698 N6 DA E 30 19.172 27.977 20.961 1.00 34.12 N ANISOU 1698 N6 DA E 30 5829 2493 4642 -1233 438 233 N ATOM 1699 N1 DA E 30 20.649 26.208 21.180 1.00 40.11 N ANISOU 1699 N1 DA E 30 6724 3035 5481 -1116 908 -105 N ATOM 1700 C2 DA E 30 21.896 25.771 21.320 1.00 42.88 C ANISOU 1700 C2 DA E 30 7092 3292 5910 -978 1143 -258 C ATOM 1701 N3 DA E 30 23.017 26.478 21.404 1.00 45.64 N ANISOU 1701 N3 DA E 30 7333 3653 6356 -855 1200 -281 N ATOM 1702 C4 DA E 30 22.772 27.791 21.336 1.00 42.02 C ANISOU 1702 C4 DA E 30 6754 3285 5926 -890 1005 -98 C ATOM 1703 P DG E 31 29.279 28.650 20.101 1.00 54.82 P ANISOU 1703 P DG E 31 7760 4592 8476 -756 2166 -885 P ATOM 1704 OP1 DG E 31 30.284 28.926 21.149 1.00 56.02 O ANISOU 1704 OP1 DG E 31 7533 4631 9119 -439 2103 -1166 O ATOM 1705 OP2 DG E 31 29.077 29.656 19.033 1.00 56.11 O ANISOU 1705 OP2 DG E 31 7986 4793 8541 -1054 2294 -590 O ATOM 1706 O5' DG E 31 29.572 27.280 19.349 1.00 59.51 O ANISOU 1706 O5' DG E 31 8617 5228 8766 -854 2445 -1057 O ATOM 1707 C5' DG E 31 29.466 26.052 20.040 1.00 54.98 C ANISOU 1707 C5' DG E 31 8127 4600 8163 -637 2384 -1240 C ATOM 1708 C4' DG E 31 28.582 25.086 19.274 1.00 62.92 C ANISOU 1708 C4' DG E 31 9473 5665 8769 -856 2437 -1210 C ATOM 1709 O4' DG E 31 27.197 25.504 19.373 1.00 79.13 O ANISOU 1709 O4' DG E 31 11622 7800 10643 -962 2150 -947 O ATOM 1710 C3' DG E 31 28.885 24.951 17.774 1.00 68.51 C ANISOU 1710 C3' DG E 31 10361 6498 9171 -1158 2727 -1271 C ATOM 1711 O3' DG E 31 29.130 23.563 17.473 1.00 77.42 O ANISOU 1711 O3' DG E 31 11639 7563 10211 -1153 2915 -1568 O ATOM 1712 C2' DG E 31 27.621 25.496 17.091 1.00 70.57 C ANISOU 1712 C2' DG E 31 10810 6942 9060 -1395 2529 -998 C ATOM 1713 C1' DG E 31 26.558 25.250 18.149 1.00 74.96 C ANISOU 1713 C1' DG E 31 11339 7415 9725 -1266 2201 -917 C ATOM 1714 N9 DG E 31 25.403 26.135 18.046 1.00 61.84 N ANISOU 1714 N9 DG E 31 9702 5878 7916 -1379 1912 -626 N ATOM 1715 C8 DG E 31 25.413 27.504 18.043 1.00 55.36 C ANISOU 1715 C8 DG E 31 8754 5101 7177 -1387 1811 -365 C ATOM 1716 N7 DG E 31 24.221 28.032 17.956 1.00 58.92 N ANISOU 1716 N7 DG E 31 9255 5653 7477 -1468 1530 -138 N ATOM 1717 C5 DG E 31 23.366 26.941 17.894 1.00 48.41 C ANISOU 1717 C5 DG E 31 8069 4356 5968 -1534 1441 -282 C ATOM 1718 C6 DG E 31 21.953 26.889 17.792 1.00 52.13 C ANISOU 1718 C6 DG E 31 8598 4926 6285 -1637 1156 -197 C ATOM 1719 O6 DG E 31 21.155 27.833 17.728 1.00 57.40 O ANISOU 1719 O6 DG E 31 9219 5695 6893 -1667 900 48 O ATOM 1720 N1 DG E 31 21.479 25.574 17.766 1.00 41.40 N ANISOU 1720 N1 DG E 31 7325 3504 4901 -1704 1193 -454 N ATOM 1721 C2 DG E 31 22.282 24.456 17.823 1.00 54.72 C ANISOU 1721 C2 DG E 31 9066 5038 6687 -1661 1474 -727 C ATOM 1722 N2 DG E 31 21.653 23.263 17.782 1.00 43.37 N ANISOU 1722 N2 DG E 31 7689 3488 5303 -1748 1497 -954 N ATOM 1723 N3 DG E 31 23.612 24.499 17.923 1.00 59.30 N ANISOU 1723 N3 DG E 31 9612 5549 7372 -1536 1722 -795 N ATOM 1724 C4 DG E 31 24.079 25.764 17.956 1.00 54.61 C ANISOU 1724 C4 DG E 31 8907 5029 6816 -1486 1687 -576 C ATOM 1725 P A DA E 32 29.125 23.026 15.955 0.60 74.20 P ANISOU 1725 P A DA E 32 11486 7329 9378 -1428 3160 -1732 P ATOM 1726 P B DA E 32 29.143 23.016 15.962 0.40 73.55 P ANISOU 1726 P B DA E 32 11402 7245 9300 -1425 3163 -1736 P ATOM 1727 OP1A DA E 32 29.808 21.712 15.959 0.60 75.92 O ANISOU 1727 OP1A DA E 32 11730 7392 9725 -1329 3390 -2110 O ATOM 1728 OP1B DA E 32 30.080 21.872 15.930 0.40 76.94 O ANISOU 1728 OP1B DA E 32 11820 7530 9886 -1316 3441 -2109 O ATOM 1729 OP2A DA E 32 29.579 24.098 15.045 0.60 71.13 O ANISOU 1729 OP2A DA E 32 11094 7132 8799 -1577 3343 -1552 O ATOM 1730 OP2B DA E 32 29.313 24.125 14.998 0.40 71.01 O ANISOU 1730 OP2B DA E 32 11116 7144 8720 -1602 3285 -1515 O ATOM 1731 O5'A DA E 32 27.582 22.762 15.643 0.60 81.11 O ANISOU 1731 O5'A DA E 32 12567 8313 9936 -1599 2874 -1649 O ATOM 1732 O5'B DA E 32 27.674 22.431 15.788 0.40 77.29 O ANISOU 1732 O5'B DA E 32 12079 7767 9520 -1562 2902 -1728 O ATOM 1733 C5'A DA E 32 26.949 21.587 16.130 0.60 71.12 C ANISOU 1733 C5'A DA E 32 11356 6861 8805 -1557 2785 -1833 C ATOM 1734 C5'B DA E 32 27.134 21.586 16.794 0.40 68.89 C ANISOU 1734 C5'B DA E 32 10983 6461 8729 -1420 2768 -1784 C ATOM 1735 C4'A DA E 32 25.668 21.336 15.371 0.60 64.12 C ANISOU 1735 C4'A DA E 32 10635 6132 7598 -1795 2587 -1886 C ATOM 1736 C4'B DA E 32 25.900 20.872 16.289 0.40 63.22 C ANISOU 1736 C4'B DA E 32 10426 5769 7824 -1625 2630 -1901 C ATOM 1737 O4'A DA E 32 24.777 22.447 15.584 0.60 64.07 O ANISOU 1737 O4'A DA E 32 10584 6267 7494 -1834 2279 -1528 O ATOM 1738 O4'B DA E 32 24.787 21.797 16.249 0.40 62.58 O ANISOU 1738 O4'B DA E 32 10343 5869 7567 -1737 2313 -1617 O ATOM 1739 C3'A DA E 32 25.843 21.205 13.857 0.60 66.18 C ANISOU 1739 C3'A DA E 32 11084 6687 7373 -1983 2722 -2112 C ATOM 1740 C3'B DA E 32 26.016 20.303 14.886 0.40 63.49 C ANISOU 1740 C3'B DA E 32 10638 5984 7502 -1836 2783 -2239 C ATOM 1741 O3'A DA E 32 25.480 19.886 13.447 0.60 66.03 O ANISOU 1741 O3'A DA E 32 11155 6585 7350 -2074 2756 -2550 O ATOM 1742 O3'B DA E 32 25.235 19.138 14.793 0.40 63.43 O ANISOU 1742 O3'B DA E 32 10646 5857 7599 -1913 2702 -2486 O ATOM 1743 C2'A DA E 32 24.917 22.284 13.257 0.60 69.25 C ANISOU 1743 C2'A DA E 32 11555 7400 7358 -2104 2443 -1818 C ATOM 1744 C2'B DA E 32 25.453 21.425 14.015 0.40 66.35 C ANISOU 1744 C2'B DA E 32 11091 6721 7397 -1994 2602 -2012 C ATOM 1745 C1'A DA E 32 24.022 22.675 14.425 0.60 66.75 C ANISOU 1745 C1'A DA E 32 11081 6908 7372 -2038 2135 -1552 C ATOM 1746 C1'B DA E 32 24.368 22.003 14.914 0.40 64.59 C ANISOU 1746 C1'B DA E 32 10758 6429 7353 -1964 2256 -1699 C ATOM 1747 N9 A DA E 32 23.618 24.088 14.426 0.60 65.26 N ANISOU 1747 N9 A DA E 32 10855 6888 7053 -2035 1927 -1132 N ATOM 1748 N9 B DA E 32 24.151 23.435 14.731 0.40 65.18 N ANISOU 1748 N9 B DA E 32 10814 6720 7231 -1979 2094 -1313 N ATOM 1749 C8 A DA E 32 24.430 25.177 14.571 0.60 62.85 C ANISOU 1749 C8 A DA E 32 10462 6581 6836 -1951 2056 -848 C ATOM 1750 C8 B DA E 32 25.100 24.416 14.687 0.40 62.92 C ANISOU 1750 C8 B DA E 32 10461 6471 6973 -1910 2264 -1091 C ATOM 1751 N7 A DA E 32 23.788 26.326 14.554 0.60 63.11 N ANISOU 1751 N7 A DA E 32 10466 6721 6790 -1963 1824 -492 N ATOM 1752 N7 B DA E 32 24.606 25.621 14.526 0.40 63.09 N ANISOU 1752 N7 B DA E 32 10471 6632 6867 -1940 2080 -733 N ATOM 1753 C5 A DA E 32 22.462 25.964 14.392 0.60 64.96 C ANISOU 1753 C5 A DA E 32 10771 7072 6840 -2048 1502 -554 C ATOM 1754 C5 B DA E 32 23.239 25.414 14.468 0.40 64.41 C ANISOU 1754 C5 B DA E 32 10700 6898 6877 -2019 1738 -734 C ATOM 1755 C6 A DA E 32 21.268 26.719 14.293 0.60 68.24 C ANISOU 1755 C6 A DA E 32 11176 7637 7114 -2078 1136 -309 C ATOM 1756 C6 B DA E 32 22.150 26.293 14.310 0.40 66.84 C ANISOU 1756 C6 B DA E 32 11012 7368 7017 -2058 1401 -452 C ATOM 1757 N6 A DA E 32 21.223 28.061 14.351 0.60 63.44 N ANISOU 1757 N6 A DA E 32 10513 7065 6528 -2019 1042 95 N ATOM 1758 N6 B DA E 32 22.281 27.617 14.175 0.40 67.71 N ANISOU 1758 N6 B DA E 32 11094 7544 7091 -2017 1371 -62 N ATOM 1759 N1 A DA E 32 20.113 26.038 14.136 0.60 71.15 N ANISOU 1759 N1 A DA E 32 11563 8087 7385 -2170 871 -522 N ATOM 1760 N1 B DA E 32 20.915 25.756 14.296 0.40 70.47 N ANISOU 1760 N1 B DA E 32 11480 7888 7409 -2136 1106 -597 N ATOM 1761 C2 A DA E 32 20.152 24.704 14.085 0.60 73.51 C ANISOU 1761 C2 A DA E 32 11888 8282 7759 -2242 988 -939 C ATOM 1762 C2 B DA E 32 20.782 24.435 14.429 0.40 72.38 C ANISOU 1762 C2 B DA E 32 11723 7994 7785 -2192 1177 -985 C ATOM 1763 N3 A DA E 32 21.204 23.891 14.159 0.60 73.51 N ANISOU 1763 N3 A DA E 32 11925 8118 7889 -2214 1332 -1175 N ATOM 1764 N3 B DA E 32 21.726 23.512 14.585 0.40 70.99 N ANISOU 1764 N3 B DA E 32 11566 7628 7778 -2157 1496 -1245 N ATOM 1765 C4 A DA E 32 22.338 24.588 14.316 0.60 66.46 C ANISOU 1765 C4 A DA E 32 11015 7188 7049 -2107 1567 -961 C ATOM 1766 C4 B DA E 32 22.942 24.073 14.597 0.40 65.67 C ANISOU 1766 C4 B DA E 32 10889 6943 7121 -2059 1751 -1103 C ATOM 1767 P A DA E 33 25.506 19.464 11.897 0.54 67.95 P ANISOU 1767 P A DA E 33 11596 7160 7060 -2230 2847 -2939 P ATOM 1768 P B DA E 33 25.511 18.071 13.632 0.46 62.21 P ANISOU 1768 P B DA E 33 10528 5829 7280 -2004 2823 -2898 P ATOM 1769 OP1A DA E 33 25.924 18.046 11.827 0.54 70.75 O ANISOU 1769 OP1A DA E 33 11813 7335 7733 -2158 2959 -3270 O ATOM 1770 OP1B DA E 33 25.325 16.733 14.233 0.46 63.50 O ANISOU 1770 OP1B DA E 33 10500 5711 7916 -1885 2810 -2972 O ATOM 1771 OP2A DA E 33 26.279 20.486 11.149 0.54 66.01 O ANISOU 1771 OP2A DA E 33 11441 7240 6401 -2211 3036 -2705 O ATOM 1772 OP2B DA E 33 26.783 18.426 12.967 0.46 71.02 O ANISOU 1772 OP2B DA E 33 11700 7120 8163 -1966 3104 -2958 O ATOM 1773 O5'A DA E 33 23.971 19.534 11.473 0.54 64.86 O ANISOU 1773 O5'A DA E 33 11255 6972 6417 -2383 2429 -2988 O ATOM 1774 O5'B DA E 33 24.348 18.351 12.583 0.46 63.00 O ANISOU 1774 O5'B DA E 33 10816 6220 6900 -2264 2589 -3107 O ATOM 1775 C5'A DA E 33 22.986 19.016 12.355 0.54 63.92 C ANISOU 1775 C5'A DA E 33 10991 6543 6755 -2422 2214 -3013 C ATOM 1776 C5'B DA E 33 23.023 18.479 13.037 0.46 62.94 C ANISOU 1776 C5'B DA E 33 10765 6131 7020 -2367 2283 -3027 C ATOM 1777 C4'A DA E 33 21.594 19.438 11.928 0.54 66.59 C ANISOU 1777 C4'A DA E 33 11321 7139 6840 -2552 1793 -2992 C ATOM 1778 C4'B DA E 33 22.222 19.335 12.086 0.46 66.51 C ANISOU 1778 C4'B DA E 33 11323 7038 6909 -2495 1977 -2975 C ATOM 1779 O4'A DA E 33 21.399 20.854 12.199 0.54 63.16 O ANISOU 1779 O4'A DA E 33 10877 6890 6233 -2482 1619 -2444 O ATOM 1780 O4'B DA E 33 22.598 20.720 12.245 0.46 64.30 O ANISOU 1780 O4'B DA E 33 11063 6942 6426 -2396 1959 -2453 O ATOM 1781 C3'A DA E 33 21.293 19.238 10.445 0.54 71.13 C ANISOU 1781 C3'A DA E 33 12055 8155 6816 -2649 1661 -3398 C ATOM 1782 C3'B DA E 33 22.426 19.007 10.605 0.46 69.75 C ANISOU 1782 C3'B DA E 33 11919 7832 6750 -2570 2018 -3397 C ATOM 1783 O3'A DA E 33 20.030 18.630 10.295 0.54 72.21 O ANISOU 1783 O3'A DA E 33 12073 8271 7092 -2788 1333 -3763 O ATOM 1784 O3'B DA E 33 21.213 18.491 10.068 0.46 72.46 O ANISOU 1784 O3'B DA E 33 12229 8303 7000 -2708 1681 -3789 O ATOM 1785 C2'A DA E 33 21.310 20.661 9.877 0.54 72.53 C ANISOU 1785 C2'A DA E 33 12373 8774 6411 -2573 1536 -2936 C ATOM 1786 C2'B DA E 33 22.831 20.351 9.962 0.46 70.15 C ANISOU 1786 C2'B DA E 33 12123 8307 6224 -2496 2034 -2974 C ATOM 1787 C1'A DA E 33 20.835 21.477 11.068 0.54 64.76 C ANISOU 1787 C1'A DA E 33 11217 7559 5830 -2533 1372 -2431 C ATOM 1788 C1'B DA E 33 22.419 21.365 11.018 0.46 67.02 C ANISOU 1788 C1'B DA E 33 11583 7753 6129 -2443 1852 -2420 C ATOM 1789 N9 A DA E 33 21.279 22.872 11.040 0.54 67.18 N ANISOU 1789 N9 A DA E 33 11585 8034 5906 -2429 1411 -1883 N ATOM 1790 N9 B DA E 33 23.211 22.598 11.013 0.46 67.83 N ANISOU 1790 N9 B DA E 33 11722 7962 6090 -2345 2021 -1940 N ATOM 1791 C8 A DA E 33 22.567 23.326 11.055 0.54 66.64 C ANISOU 1791 C8 A DA E 33 11560 7921 5840 -2344 1785 -1673 C ATOM 1792 C8 B DA E 33 24.575 22.716 10.979 0.46 63.32 C ANISOU 1792 C8 B DA E 33 11156 7318 5587 -2273 2436 -1893 C ATOM 1793 N7 A DA E 33 22.670 24.632 11.028 0.54 66.61 N ANISOU 1793 N7 A DA E 33 11566 8027 5716 -2282 1762 -1182 N ATOM 1794 N7 B DA E 33 25.000 23.961 10.992 0.46 62.36 N ANISOU 1794 N7 B DA E 33 11012 7263 5418 -2219 2526 -1437 N ATOM 1795 C5 A DA E 33 21.356 25.070 10.992 0.54 64.98 C ANISOU 1795 C5 A DA E 33 11345 7970 5375 -2305 1323 -1045 C ATOM 1796 C5 B DA E 33 23.834 24.707 11.040 0.46 65.42 C ANISOU 1796 C5 B DA E 33 11409 7781 5667 -2239 2131 -1148 C ATOM 1797 C6 A DA E 33 20.782 26.363 10.956 0.54 63.67 C ANISOU 1797 C6 A DA E 33 11177 7938 5078 -2245 1086 -567 C ATOM 1798 C6 B DA E 33 23.585 26.100 11.075 0.46 61.07 C ANISOU 1798 C6 B DA E 33 10838 7305 5061 -2195 2014 -628 C ATOM 1799 N6 A DA E 33 21.498 27.491 10.942 0.54 61.09 N ANISOU 1799 N6 A DA E 33 10863 7580 4770 -2170 1296 -117 N ATOM 1800 N6 B DA E 33 24.544 27.037 11.065 0.46 61.10 N ANISOU 1800 N6 B DA E 33 10793 7234 5187 -2145 2320 -295 N ATOM 1801 N1 A DA E 33 19.435 26.446 10.929 0.54 65.47 N ANISOU 1801 N1 A DA E 33 11357 8301 5219 -2267 635 -589 N ATOM 1802 N1 B DA E 33 22.302 26.494 11.119 0.46 60.59 N ANISOU 1802 N1 B DA E 33 10776 7364 4880 -2205 1580 -481 N ATOM 1803 C2 A DA E 33 18.722 25.313 10.941 0.54 65.83 C ANISOU 1803 C2 A DA E 33 11335 8328 5349 -2368 457 -1073 C ATOM 1804 C2 B DA E 33 21.333 25.575 11.129 0.46 64.45 C ANISOU 1804 C2 B DA E 33 11256 7897 5337 -2276 1293 -844 C ATOM 1805 N3 A DA E 33 19.145 24.049 10.978 0.54 63.36 N ANISOU 1805 N3 A DA E 33 11014 7852 5208 -2448 670 -1539 N ATOM 1806 N3 B DA E 33 21.438 24.251 11.101 0.46 63.03 N ANISOU 1806 N3 B DA E 33 11075 7620 5253 -2345 1385 -1346 N ATOM 1807 C4 A DA E 33 20.485 23.997 10.998 0.54 63.87 C ANISOU 1807 C4 A DA E 33 11156 7806 5305 -2399 1098 -1488 C ATOM 1808 C4 B DA E 33 22.725 23.878 11.056 0.46 65.48 C ANISOU 1808 C4 B DA E 33 11418 7812 5649 -2313 1809 -1462 C ATOM 1809 P A DG E 34 19.510 18.216 8.837 0.59 79.43 P ANISOU 1809 P A DG E 34 13051 9649 7481 -2823 1074 -4302 P ATOM 1810 P B DG E 34 21.036 18.263 8.488 0.41 79.49 P ANISOU 1810 P B DG E 34 13243 9728 7230 -2696 1523 -4206 P ATOM 1811 OP1A DG E 34 18.623 17.043 9.002 0.59 81.40 O ANISOU 1811 OP1A DG E 34 12984 9614 8332 -2877 884 -4701 O ATOM 1812 OP1B DG E 34 20.076 17.150 8.322 0.41 85.12 O ANISOU 1812 OP1B DG E 34 13708 10314 8322 -2744 1244 -4681 O ATOM 1813 OP2A DG E 34 20.687 18.145 7.942 0.59 83.42 O ANISOU 1813 OP2A DG E 34 13751 10426 7518 -2693 1370 -4389 O ATOM 1814 OP2B DG E 34 22.369 18.173 7.851 0.41 81.21 O ANISOU 1814 OP2B DG E 34 13595 10102 7158 -2566 1904 -4226 O ATOM 1815 O5'A DG E 34 18.623 19.466 8.389 0.59 83.97 O ANISOU 1815 O5'A DG E 34 13717 10698 7489 -2802 654 -3999 O ATOM 1816 O5'B DG E 34 20.308 19.599 8.016 0.41 79.48 O ANISOU 1816 O5'B DG E 34 13393 10204 6603 -2680 1187 -3848 O ATOM 1817 C5'A DG E 34 17.550 19.888 9.214 0.59 77.79 C ANISOU 1817 C5'A DG E 34 12716 9743 7099 -2855 351 -3735 C ATOM 1818 C5'B DG E 34 19.266 20.131 8.818 0.41 78.64 C ANISOU 1818 C5'B DG E 34 13103 9951 6826 -2721 855 -3533 C ATOM 1819 C4'A DG E 34 16.905 21.149 8.673 0.59 77.80 C ANISOU 1819 C4'A DG E 34 12804 10223 6532 -2748 -27 -3369 C ATOM 1820 C4'B DG E 34 18.905 21.532 8.378 0.41 79.85 C ANISOU 1820 C4'B DG E 34 13380 10527 6433 -2608 609 -3026 C ATOM 1821 O4'A DG E 34 17.783 22.283 8.884 0.59 79.29 O ANISOU 1821 O4'A DG E 34 13155 10457 6514 -2609 212 -2710 O ATOM 1822 O4'B DG E 34 19.995 22.443 8.683 0.41 76.45 O ANISOU 1822 O4'B DG E 34 13049 10031 5966 -2502 957 -2464 O ATOM 1823 C3'A DG E 34 16.587 21.131 7.175 0.59 86.31 C ANISOU 1823 C3'A DG E 34 14065 11918 6809 -2667 -306 -3747 C ATOM 1824 C3'B DG E 34 18.627 21.683 6.879 0.41 85.97 C ANISOU 1824 C3'B DG E 34 14385 11935 6346 -2515 396 -3262 C ATOM 1825 O3'A DG E 34 15.246 21.561 6.977 0.59 91.25 O ANISOU 1825 O3'A DG E 34 14552 12796 7323 -2648 -856 -3782 O ATOM 1826 O3'B DG E 34 17.417 22.403 6.693 0.41 88.38 O ANISOU 1826 O3'B DG E 34 14639 12515 6427 -2463 -110 -3090 O ATOM 1827 C2'A DG E 34 17.594 22.129 6.588 0.59 88.39 C ANISOU 1827 C2'A DG E 34 14657 12508 6419 -2477 -39 -3224 C ATOM 1828 C2'B DG E 34 19.835 22.476 6.374 0.41 85.41 C ANISOU 1828 C2'B DG E 34 14582 12074 5796 -2370 806 -2814 C ATOM 1829 C1'A DG E 34 17.720 23.100 7.746 0.59 82.66 C ANISOU 1829 C1'A DG E 34 13821 11432 6155 -2469 56 -2531 C ATOM 1830 C1'B DG E 34 20.156 23.317 7.596 0.41 80.12 C ANISOU 1830 C1'B DG E 34 13763 10985 5694 -2380 947 -2202 C ATOM 1831 N9 A DG E 34 18.899 23.973 7.709 0.59 80.02 N ANISOU 1831 N9 A DG E 34 13668 11106 5630 -2359 459 -1994 N ATOM 1832 N9 B DG E 34 21.512 23.870 7.613 0.41 80.21 N ANISOU 1832 N9 B DG E 34 13873 10917 5686 -2311 1445 -1838 N ATOM 1833 C8 A DG E 34 20.221 23.608 7.598 0.59 80.55 C ANISOU 1833 C8 A DG E 34 13837 11062 5707 -2355 964 -2059 C ATOM 1834 C8 B DG E 34 22.699 23.186 7.487 0.41 78.18 C ANISOU 1834 C8 B DG E 34 13654 10541 5511 -2323 1902 -2096 C ATOM 1835 N7 A DG E 34 21.044 24.627 7.610 0.59 80.73 N ANISOU 1835 N7 A DG E 34 13950 11084 5638 -2266 1257 -1517 N ATOM 1836 N7 B DG E 34 23.752 23.959 7.540 0.41 76.77 N ANISOU 1836 N7 B DG E 34 13504 10300 5365 -2261 2294 -1686 N ATOM 1837 C5 A DG E 34 20.212 25.733 7.744 0.59 78.72 C ANISOU 1837 C5 A DG E 34 13672 10928 5310 -2199 925 -1049 C ATOM 1838 C5 B DG E 34 23.228 25.236 7.713 0.41 76.36 C ANISOU 1838 C5 B DG E 34 13445 10303 5264 -2209 2090 -1112 C ATOM 1839 C6 A DG E 34 20.521 27.119 7.816 0.59 78.22 C ANISOU 1839 C6 A DG E 34 13653 10850 5216 -2098 1040 -378 C ATOM 1840 C6 B DG E 34 23.884 26.488 7.839 0.41 75.50 C ANISOU 1840 C6 B DG E 34 13322 10108 5258 -2149 2352 -520 C ATOM 1841 O6 A DG E 34 21.634 27.670 7.778 0.59 79.47 O ANISOU 1841 O6 A DG E 34 13860 10896 5441 -2066 1488 -62 O ATOM 1842 O6 B DG E 34 25.099 26.728 7.824 0.41 76.73 O ANISOU 1842 O6 B DG E 34 13445 10128 5583 -2140 2834 -395 O ATOM 1843 N1 A DG E 34 19.370 27.893 7.951 0.59 77.00 N ANISOU 1843 N1 A DG E 34 13442 10789 5024 -2036 584 -94 N ATOM 1844 N1 B DG E 34 22.975 27.530 7.999 0.41 76.98 N ANISOU 1844 N1 B DG E 34 13495 10345 5411 -2099 2004 -74 N ATOM 1845 C2 A DG E 34 18.089 27.396 8.006 0.59 76.44 C ANISOU 1845 C2 A DG E 34 13261 10836 4948 -2073 82 -430 C ATOM 1846 C2 B DG E 34 21.608 27.382 8.036 0.41 77.29 C ANISOU 1846 C2 B DG E 34 13521 10533 5313 -2100 1463 -192 C ATOM 1847 N2 A DG E 34 17.106 28.292 8.134 0.59 74.39 N ANISOU 1847 N2 A DG E 34 12931 10661 4673 -1986 -314 -98 N ATOM 1848 N2 B DG E 34 20.893 28.503 8.194 0.41 76.25 N ANISOU 1848 N2 B DG E 34 13360 10426 5186 -2026 1186 283 N ATOM 1849 N3 A DG E 34 17.790 26.111 7.938 0.59 75.69 N ANISOU 1849 N3 A DG E 34 13094 10743 4923 -2190 -13 -1069 N ATOM 1850 N3 B DG E 34 20.984 26.220 7.918 0.41 77.68 N ANISOU 1850 N3 B DG E 34 13555 10673 5290 -2171 1219 -761 N ATOM 1851 C4 A DG E 34 18.893 25.342 7.803 0.59 77.49 C ANISOU 1851 C4 A DG E 34 13402 10862 5178 -2244 424 -1337 C ATOM 1852 C4 B DG E 34 21.853 25.194 7.760 0.41 78.63 C ANISOU 1852 C4 B DG E 34 13702 10715 5457 -2226 1560 -1192 C ATOM 1853 P A DC E 35 14.263 20.751 5.997 0.52111.69 P ANISOU 1853 P A DC E 35 17024 15738 9673 -2678 -1320 -4611 P ATOM 1854 P B DC E 35 16.300 21.868 5.671 0.48113.18 P ANISOU 1854 P B DC E 35 17752 16111 9139 -2442 -626 -3730 P ATOM 1855 OP1A DC E 35 13.078 20.361 6.792 0.52110.29 O ANISOU 1855 OP1A DC E 35 16422 15191 10292 -2846 -1597 -4811 O ATOM 1856 OP1B DC E 35 15.049 21.699 6.448 0.48103.87 O ANISOU 1856 OP1B DC E 35 16217 14661 8588 -2583 -1012 -3862 O ATOM 1857 OP2A DC E 35 15.051 19.718 5.287 0.52116.29 O ANISOU 1857 OP2A DC E 35 17678 16326 10181 -2584 -1057 -5068 O ATOM 1858 OP2B DC E 35 16.868 20.724 4.925 0.48119.58 O ANISOU 1858 OP2B DC E 35 18632 17017 9786 -2443 -434 -4390 O ATOM 1859 O5'A DC E 35 13.819 21.844 4.920 0.52120.75 O ANISOU 1859 O5'A DC E 35 18399 17612 9867 -2388 -1735 -4352 O ATOM 1860 O5'B DC E 35 16.121 23.076 4.637 0.48118.01 O ANISOU 1860 O5'B DC E 35 18659 17376 8803 -2163 -853 -3296 O ATOM 1861 C5'A DC E 35 14.612 23.009 4.735 0.52120.49 C ANISOU 1861 C5'A DC E 35 18699 17778 9303 -2197 -1482 -3587 C ATOM 1862 C5'B DC E 35 17.185 23.996 4.434 0.48117.83 C ANISOU 1862 C5'B DC E 35 18921 17439 8412 -2021 -426 -2638 C ATOM 1863 C4'A DC E 35 13.761 24.261 4.816 0.52120.17 C ANISOU 1863 C4'A DC E 35 18638 17937 9084 -2038 -1878 -3026 C ATOM 1864 C4'B DC E 35 16.934 25.290 5.190 0.48114.62 C ANISOU 1864 C4'B DC E 35 18444 16826 8282 -1978 -493 -1863 C ATOM 1865 O4'A DC E 35 14.571 25.367 5.287 0.52115.00 O ANISOU 1865 O4'A DC E 35 18149 17093 8454 -1964 -1503 -2186 O ATOM 1866 O4'B DC E 35 18.170 25.730 5.817 0.48110.26 O ANISOU 1866 O4'B DC E 35 17923 15896 8075 -2020 63 -1401 O ATOM 1867 C3'A DC E 35 13.195 24.724 3.488 0.52127.16 C ANISOU 1867 C3'A DC E 35 19744 19571 8999 -1729 -2322 -3096 C ATOM 1868 C3'B DC E 35 16.508 26.455 4.317 0.48118.77 C ANISOU 1868 C3'B DC E 35 19212 17856 8058 -1702 -736 -1368 C ATOM 1869 O3'A DC E 35 12.019 25.491 3.704 0.52126.39 O ANISOU 1869 O3'A DC E 35 19466 19573 8985 -1632 -2846 -2857 O ATOM 1870 O3'B DC E 35 15.812 27.427 5.097 0.48115.37 O ANISOU 1870 O3'B DC E 35 18602 17201 8031 -1690 -995 -868 O ATOM 1871 C2'A DC E 35 14.336 25.575 2.932 0.52128.46 C ANISOU 1871 C2'A DC E 35 20342 19953 8513 -1511 -1865 -2427 C ATOM 1872 C2'B DC E 35 17.855 26.982 3.850 0.48119.38 C ANISOU 1872 C2'B DC E 35 19588 17992 7777 -1599 -127 -904 C ATOM 1873 C1'A DC E 35 14.922 26.207 4.199 0.52120.75 C ANISOU 1873 C1'A DC E 35 19250 18340 8289 -1679 -1466 -1786 C ATOM 1874 C1'B DC E 35 18.681 26.856 5.123 0.48111.99 C ANISOU 1874 C1'B DC E 35 18416 16390 7745 -1826 275 -792 C ATOM 1875 N1 A DC E 35 16.414 26.338 4.165 0.52119.58 N ANISOU 1875 N1 A DC E 35 19327 18035 8073 -1690 -788 -1463 N ATOM 1876 N1 B DC E 35 20.136 26.638 4.869 0.48112.35 N ANISOU 1876 N1 B DC E 35 18602 16357 7727 -1843 915 -764 N ATOM 1877 C2 A DC E 35 17.011 27.591 4.366 0.52117.57 C ANISOU 1877 C2 A DC E 35 19201 17652 7817 -1589 -486 -647 C ATOM 1878 C2 B DC E 35 21.026 27.722 4.917 0.48110.96 C ANISOU 1878 C2 B DC E 35 18510 16048 7603 -1778 1351 -97 C ATOM 1879 O2 A DC E 35 16.293 28.578 4.570 0.52117.37 O ANISOU 1879 O2 A DC E 35 19128 17641 7827 -1479 -789 -185 O ATOM 1880 O2 B DC E 35 20.590 28.852 5.174 0.48108.65 O ANISOU 1880 O2 B DC E 35 18189 15685 7410 -1702 1193 466 O ATOM 1881 N3 A DC E 35 18.365 27.686 4.333 0.52115.90 N ANISOU 1881 N3 A DC E 35 19129 17278 7629 -1616 141 -412 N ATOM 1882 N3 B DC E 35 22.345 27.498 4.686 0.48110.38 N ANISOU 1882 N3 B DC E 35 18510 15894 7535 -1806 1949 -115 N ATOM 1883 C4 A DC E 35 19.106 26.598 4.110 0.52116.98 C ANISOU 1883 C4 A DC E 35 19299 17402 7745 -1717 447 -941 C ATOM 1884 C4 B DC E 35 22.774 26.263 4.415 0.48111.20 C ANISOU 1884 C4 B DC E 35 18632 16061 7556 -1872 2098 -751 C ATOM 1885 N4 A DC E 35 20.436 26.741 4.085 0.52116.10 N ANISOU 1885 N4 A DC E 35 19286 17131 7695 -1734 1064 -710 N ATOM 1886 N4 B DC E 35 24.079 26.087 4.192 0.48111.71 N ANISOU 1886 N4 B DC E 35 18745 16049 7651 -1884 2695 -763 N ATOM 1887 C5 A DC E 35 18.517 25.316 3.902 0.52119.99 C ANISOU 1887 C5 A DC E 35 19577 17902 8111 -1806 144 -1760 C ATOM 1888 C5 B DC E 35 21.883 25.152 4.358 0.48112.66 C ANISOU 1888 C5 B DC E 35 18751 16360 7694 -1933 1657 -1429 C ATOM 1889 C6 A DC E 35 17.183 25.233 3.937 0.52120.84 C ANISOU 1889 C6 A DC E 35 19527 18146 8240 -1800 -461 -1999 C ATOM 1890 C6 B DC E 35 20.588 25.383 4.588 0.48113.20 C ANISOU 1890 C6 B DC E 35 18723 16494 7795 -1926 1085 -1414 C ATOM 1891 P A DA E 36 10.864 25.528 2.588 0.65128.68 P ANISOU 1891 P A DA E 36 19715 20380 8797 -1237 -3516 -3210 P ATOM 1892 P B DA E 36 14.432 28.060 4.563 0.35119.94 P ANISOU 1892 P B DA E 36 19173 18209 8188 -1477 -1656 -776 P ATOM 1893 OP1A DA E 36 9.619 25.017 3.202 0.65129.18 O ANISOU 1893 OP1A DA E 36 19308 20160 9616 -1457 -3962 -3686 O ATOM 1894 OP1B DA E 36 13.499 28.086 5.713 0.35112.88 O ANISOU 1894 OP1B DA E 36 17877 16923 8088 -1639 -1973 -835 O ATOM 1895 OP2A DA E 36 11.390 24.869 1.371 0.65129.53 O ANISOU 1895 OP2A DA E 36 20154 20761 8299 -1060 -3415 -3579 O ATOM 1896 OP2B DA E 36 14.055 27.349 3.320 0.35124.54 O ANISOU 1896 OP2B DA E 36 19919 19402 8000 -1327 -1949 -1363 O ATOM 1897 O5'A DA E 36 10.681 27.089 2.292 0.65130.18 O ANISOU 1897 O5'A DA E 36 20127 20890 8447 -870 -3655 -2347 O ATOM 1898 O5'B DA E 36 14.807 29.570 4.164 0.35116.62 O ANISOU 1898 O5'B DA E 36 19037 17928 7346 -1213 -1485 134 O ATOM 1899 C5'A DA E 36 11.786 27.974 2.442 0.65125.72 C ANISOU 1899 C5'A DA E 36 19861 20247 7660 -853 -3100 -1534 C ATOM 1900 C5'B DA E 36 16.173 29.997 4.132 0.35116.11 C ANISOU 1900 C5'B DA E 36 19173 17669 7275 -1221 -819 593 C ATOM 1901 C4'A DA E 36 12.225 28.518 1.097 0.65133.88 C ANISOU 1901 C4'A DA E 36 21298 21817 7754 -331 -2978 -1203 C ATOM 1902 C4'B DA E 36 16.618 30.280 2.706 0.35121.57 C ANISOU 1902 C4'B DA E 36 20262 18921 7008 -904 -613 823 C ATOM 1903 O4'A DA E 36 13.483 29.211 1.244 0.65131.57 O ANISOU 1903 O4'A DA E 36 21244 21344 7404 -383 -2293 -468 O ATOM 1904 O4'B DA E 36 18.027 29.970 2.561 0.35121.31 O ANISOU 1904 O4'B DA E 36 20347 18745 6999 -994 80 844 O ATOM 1905 C3'A DA E 36 12.501 27.471 0.035 0.65139.79 C ANISOU 1905 C3'A DA E 36 22400 22685 8028 -355 -2980 -1822 C ATOM 1906 C3'B DA E 36 15.888 29.465 1.636 0.35127.38 C ANISOU 1906 C3'B DA E 36 21025 20283 7090 -658 -1044 183 C ATOM 1907 O3'A DA E 36 11.289 27.076 -0.592 0.65144.57 O ANISOU 1907 O3'A DA E 36 22835 23587 8508 -455 -3597 -2311 O ATOM 1908 O3'B DA E 36 15.180 30.332 0.765 0.35133.41 O ANISOU 1908 O3'B DA E 36 21860 21548 7282 -199 -1356 577 O ATOM 1909 C2'A DA E 36 13.404 28.235 -0.924 0.65146.34 C ANISOU 1909 C2'A DA E 36 23688 23787 8127 -243 -2509 -1144 C ATOM 1910 C2'B DA E 36 17.000 28.703 0.898 0.35131.06 C ANISOU 1910 C2'B DA E 36 21660 20942 7194 -610 -538 -119 C ATOM 1911 C1'A DA E 36 14.223 29.104 0.037 0.65140.07 C ANISOU 1911 C1'A DA E 36 22620 22879 7723 -39 -1970 -442 C ATOM 1912 C1'B DA E 36 18.253 29.489 1.262 0.35126.38 C ANISOU 1912 C1'B DA E 36 21155 19963 6901 -702 166 583 C ATOM 1913 N9 A DA E 36 15.537 28.550 0.342 0.65136.96 N ANISOU 1913 N9 A DA E 36 22318 22163 7559 -337 -1318 -513 N ATOM 1914 N9 B DA E 36 19.472 28.672 1.258 0.35124.02 N ANISOU 1914 N9 B DA E 36 20878 19504 6740 -873 723 255 N ATOM 1915 C8 A DA E 36 15.892 27.228 0.360 0.65135.26 C ANISOU 1915 C8 A DA E 36 22040 21851 7501 -550 -1222 -1293 C ATOM 1916 C8 B DA E 36 19.557 27.325 1.027 0.35124.79 C ANISOU 1916 C8 B DA E 36 20933 19719 6764 -961 667 -568 C ATOM 1917 N7 A DA E 36 17.151 27.024 0.664 0.65132.09 N ANISOU 1917 N7 A DA E 36 21707 21146 7333 -759 -577 -1167 N ATOM 1918 N7 B DA E 36 20.779 26.851 1.081 0.35123.14 N ANISOU 1918 N7 B DA E 36 20722 19302 6763 -1075 1240 -686 N ATOM 1919 C5 A DA E 36 17.657 28.301 0.855 0.65130.67 C ANISOU 1919 C5 A DA E 36 21648 20820 7181 -691 -230 -262 C ATOM 1920 C5 B DA E 36 21.556 27.962 1.359 0.35120.40 C ANISOU 1920 C5 B DA E 36 20401 18694 6652 -1077 1704 88 C ATOM 1921 C6 A DA E 36 18.938 28.772 1.198 0.65125.65 C ANISOU 1921 C6 A DA E 36 21076 19819 6847 -814 461 241 C ATOM 1922 C6 B DA E 36 22.945 28.127 1.540 0.35117.10 C ANISOU 1922 C6 B DA E 36 19925 17969 6599 -1165 2382 328 C ATOM 1923 N6 A DA E 36 19.980 27.965 1.415 0.65122.37 N ANISOU 1923 N6 A DA E 36 20630 19162 6701 -1022 926 -107 N ATOM 1924 N6 B DA E 36 23.821 27.121 1.460 0.35114.41 N ANISOU 1924 N6 B DA E 36 19525 17559 6388 -1255 2713 -181 N ATOM 1925 N1 A DA E 36 19.106 30.109 1.307 0.65123.94 N ANISOU 1925 N1 A DA E 36 20894 19464 6735 -696 651 1086 N ATOM 1926 N1 B DA E 36 23.399 29.371 1.805 0.35116.21 N ANISOU 1926 N1 B DA E 36 19758 17596 6799 -1146 2688 1083 N ATOM 1927 C2 A DA E 36 18.059 30.912 1.087 0.65126.08 C ANISOU 1927 C2 A DA E 36 21160 19964 6781 -458 185 1435 C ATOM 1928 C2 B DA E 36 22.516 30.376 1.884 0.35117.21 C ANISOU 1928 C2 B DA E 36 19914 17760 6861 -1032 2347 1590 C ATOM 1929 N3 A DA E 36 16.809 30.587 0.760 0.65130.62 N ANISOU 1929 N3 A DA E 36 21685 20925 7018 -302 -488 1036 N ATOM 1930 N3 B DA E 36 21.190 30.344 1.733 0.35118.93 N ANISOU 1930 N3 B DA E 36 20208 18270 6709 -918 1706 1460 N ATOM 1931 C4 A DA E 36 16.675 29.253 0.658 0.65133.33 C ANISOU 1931 C4 A DA E 36 21979 21385 7295 -437 -668 166 C ATOM 1932 C4 B DA E 36 20.769 29.096 1.470 0.35121.29 C ANISOU 1932 C4 B DA E 36 20539 18836 6708 -955 1403 679 C TER 1933 DA E 36 HETATM 1934 ZN ZN A 701 12.664 10.208 19.143 1.00 57.61 ZN HETATM 1935 ZN ZN A 702 0.690 32.183 17.448 1.00 40.63 ZN HETATM 1936 ZN ZN A 703 25.872 46.789 18.671 1.00 30.60 ZN HETATM 1937 CL CL A 704 11.074 45.950 23.362 0.50 28.56 CL HETATM 1938 O HOH A 801 4.215 11.382 25.362 1.00 56.24 O HETATM 1939 O HOH A 802 12.720 23.377 27.074 1.00 33.51 O HETATM 1940 O HOH A 803 0.944 32.465 15.312 1.00 33.19 O HETATM 1941 O HOH A 804 26.925 34.057 20.206 1.00 38.48 O HETATM 1942 O HOH A 805 8.520 28.568 17.839 1.00 51.86 O HETATM 1943 O HOH A 806 10.406 47.259 31.244 1.00 25.94 O HETATM 1944 O HOH A 807 15.995 45.852 31.888 1.00 48.36 O HETATM 1945 O HOH A 808 8.571 45.547 25.266 1.00 23.45 O HETATM 1946 O HOH A 809 -4.387 34.837 15.181 1.00 58.85 O HETATM 1947 O HOH A 810 9.552 39.487 19.487 1.00 26.63 O HETATM 1948 O HOH A 811 21.388 40.894 13.422 1.00 35.87 O HETATM 1949 O HOH A 812 -3.382 27.605 19.147 1.00 51.01 O HETATM 1950 O HOH A 813 11.686 37.397 32.260 1.00 47.81 O HETATM 1951 O HOH A 814 0.619 39.046 17.086 1.00 46.22 O HETATM 1952 O HOH A 815 16.211 34.098 14.175 1.00 62.14 O HETATM 1953 O HOH A 816 0.596 30.449 26.169 1.00 33.63 O HETATM 1954 O HOH A 817 38.047 41.106 16.302 1.00 37.61 O HETATM 1955 O HOH A 818 7.256 37.307 31.873 1.00 51.08 O HETATM 1956 O HOH A 819 12.935 35.387 24.453 1.00 31.08 O HETATM 1957 O HOH A 820 34.236 40.657 27.069 1.00 47.02 O HETATM 1958 O HOH A 821 5.001 43.232 32.085 1.00 38.34 O HETATM 1959 O HOH A 822 16.972 33.347 21.348 1.00 39.86 O HETATM 1960 O HOH A 823 12.832 39.282 22.495 1.00 30.71 O HETATM 1961 O HOH A 824 4.262 42.309 16.619 1.00 42.03 O HETATM 1962 O HOH A 825 6.469 4.618 23.068 1.00 63.63 O HETATM 1963 O HOH A 826 13.208 35.468 39.835 1.00 69.95 O HETATM 1964 O HOH A 827 23.741 52.914 18.025 1.00 62.02 O HETATM 1965 O HOH A 828 9.274 38.223 11.281 1.00 66.39 O HETATM 1966 O HOH A 829 35.632 38.444 20.831 1.00 52.53 O HETATM 1967 O HOH A 830 15.180 17.690 24.498 1.00 28.31 O HETATM 1968 O HOH A 831 23.649 44.531 12.551 1.00 42.90 O HETATM 1969 O HOH A 832 24.875 41.943 30.810 1.00 50.07 O HETATM 1970 O HOH A 833 10.349 23.229 26.238 1.00 36.89 O HETATM 1971 O HOH A 834 19.944 2.237 35.683 1.00 68.29 O HETATM 1972 O HOH A 835 28.664 52.004 19.165 1.00 41.11 O HETATM 1973 O HOH A 836 15.750 41.659 15.947 1.00 36.92 O HETATM 1974 O HOH A 837 7.223 31.816 14.869 1.00 57.81 O HETATM 1975 O HOH A 838 12.884 35.257 22.118 1.00 36.33 O HETATM 1976 O HOH A 839 21.706 39.602 31.126 1.00 46.40 O HETATM 1977 O HOH A 840 26.575 34.171 15.133 1.00 48.02 O HETATM 1978 O HOH A 841 23.017 51.913 11.997 1.00 68.90 O HETATM 1979 O HOH A 842 11.464 34.973 19.425 1.00 45.92 O HETATM 1980 O HOH A 843 10.488 48.407 13.658 1.00 58.41 O HETATM 1981 O HOH A 844 29.497 38.118 36.749 1.00 70.79 O HETATM 1982 O HOH A 845 30.166 -0.361 30.208 1.00 51.97 O HETATM 1983 O HOH A 846 33.164 45.948 24.756 0.50 55.62 O HETATM 1984 O HOH A 847 -4.435 37.902 19.063 1.00 39.38 O HETATM 1985 O HOH A 848 -3.092 12.941 21.555 1.00 56.02 O HETATM 1986 O HOH A 849 14.522 33.583 22.420 1.00 40.75 O HETATM 1987 O HOH A 850 15.549 31.121 24.663 1.00 23.96 O HETATM 1988 O HOH A 851 30.832 45.895 25.599 1.00 46.32 O HETATM 1989 O HOH A 852 10.100 43.303 33.447 1.00 35.25 O HETATM 1990 O HOH A 853 12.808 37.145 42.065 1.00 68.98 O HETATM 1991 O HOH D 101 2.979 23.884 45.000 1.00 80.37 O HETATM 1992 O HOH D 102 26.550 24.233 34.368 1.00 62.79 O HETATM 1993 O HOH D 103 23.084 20.769 25.256 1.00 31.36 O HETATM 1994 O HOH D 104 22.257 20.989 22.252 1.00 57.54 O HETATM 1995 O HOH D 105 15.707 18.463 29.660 1.00 49.17 O HETATM 1996 O HOH D 106 15.537 17.806 22.210 1.00 32.19 O HETATM 1997 O HOH D 107 14.138 18.056 12.506 1.00 69.38 O HETATM 1998 O HOH D 108 24.282 22.900 28.236 1.00 42.63 O HETATM 1999 O HOH D 109 19.334 18.199 35.713 1.00 57.40 O HETATM 2000 O HOH D 110 23.765 41.087 11.285 1.00 59.28 O HETATM 2001 O HOH D 111 21.829 18.286 34.228 1.00 56.83 O HETATM 2002 O HOH E 101 21.557 28.081 29.154 1.00 50.22 O HETATM 2003 O HOH E 102 25.039 24.955 21.417 1.00 38.83 O HETATM 2004 O HOH E 103 17.955 31.931 23.886 1.00 22.16 O HETATM 2005 O HOH E 104 8.400 21.382 29.152 1.00 46.58 O HETATM 2006 O HOH E 105 20.820 35.082 29.694 1.00 35.07 O HETATM 2007 O HOH E 106 26.777 34.908 26.811 1.00 44.20 O HETATM 2008 O HOH E 107 14.944 33.975 25.389 1.00 23.39 O HETATM 2009 O HOH E 108 12.970 34.963 32.103 1.00 43.45 O HETATM 2010 O HOH E 109 17.303 29.668 31.682 1.00 57.87 O HETATM 2011 O HOH E 110 11.567 29.357 25.629 1.00 28.99 O HETATM 2012 O HOH E 111 24.688 23.509 25.636 1.00 39.91 O HETATM 2013 O HOH E 112 24.046 26.793 27.350 1.00 46.11 O CONECT 138 1934 CONECT 159 1934 CONECT 271 1934 CONECT 308 1934 CONECT 380 1935 CONECT 409 1935 CONECT 523 1935 CONECT 560 1935 CONECT 629 1936 CONECT 648 1936 CONECT 765 1936 CONECT 805 1936 CONECT 1217 1246 CONECT 1229 1230 1235 1238 CONECT 1230 1229 1231 1236 CONECT 1231 1230 1232 CONECT 1232 1231 1233 1237 CONECT 1233 1232 1234 1235 CONECT 1234 1233 CONECT 1235 1229 1233 CONECT 1236 1230 CONECT 1237 1232 CONECT 1238 1229 1239 1242 CONECT 1239 1238 1240 CONECT 1240 1239 1241 1243 CONECT 1241 1240 1242 1244 CONECT 1242 1238 1241 CONECT 1243 1240 1249 CONECT 1244 1241 1245 CONECT 1245 1244 1246 CONECT 1246 1217 1245 1247 1248 CONECT 1247 1246 CONECT 1248 1246 CONECT 1249 1243 CONECT 1257 1288 CONECT 1271 1272 1277 1280 CONECT 1272 1271 1273 1278 CONECT 1273 1272 1274 CONECT 1274 1273 1275 1279 CONECT 1275 1274 1276 1277 CONECT 1276 1275 CONECT 1277 1271 1275 CONECT 1278 1272 CONECT 1279 1274 CONECT 1280 1271 1281 1284 CONECT 1281 1280 1282 CONECT 1282 1281 1283 1285 CONECT 1283 1282 1284 1286 CONECT 1284 1280 1283 CONECT 1285 1282 1291 CONECT 1286 1283 1287 CONECT 1287 1286 1288 CONECT 1288 1257 1287 1289 1290 CONECT 1289 1288 CONECT 1290 1288 CONECT 1291 1285 CONECT 1586 1615 CONECT 1598 1599 1604 1607 CONECT 1599 1598 1600 1605 CONECT 1600 1599 1601 CONECT 1601 1600 1602 1606 CONECT 1602 1601 1603 1604 CONECT 1603 1602 CONECT 1604 1598 1602 CONECT 1605 1599 CONECT 1606 1601 CONECT 1607 1598 1608 1611 CONECT 1608 1607 1609 CONECT 1609 1608 1610 1612 CONECT 1610 1609 1611 1613 CONECT 1611 1607 1610 CONECT 1612 1609 1618 CONECT 1613 1610 1614 CONECT 1614 1613 1615 CONECT 1615 1586 1614 1616 1617 CONECT 1616 1615 CONECT 1617 1615 CONECT 1618 1612 CONECT 1626 1657 CONECT 1640 1641 1646 1649 CONECT 1641 1640 1642 1647 CONECT 1642 1641 1643 CONECT 1643 1642 1644 1648 CONECT 1644 1643 1645 1646 CONECT 1645 1644 CONECT 1646 1640 1644 CONECT 1647 1641 CONECT 1648 1643 CONECT 1649 1640 1650 1653 CONECT 1650 1649 1651 CONECT 1651 1650 1652 1654 CONECT 1652 1651 1653 1655 CONECT 1653 1649 1652 CONECT 1654 1651 1660 CONECT 1655 1652 1656 CONECT 1656 1655 1657 CONECT 1657 1626 1656 1658 1659 CONECT 1658 1657 CONECT 1659 1657 CONECT 1660 1654 CONECT 1934 138 159 271 308 CONECT 1935 380 409 523 560 CONECT 1935 1940 CONECT 1936 629 648 765 805 CONECT 1940 1935 MASTER 534 0 8 3 8 0 5 6 1799 3 105 15 END
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Related entries of code: 5vmv
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
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Protein Sequence Similarity
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Complexes with the same small molecule ligand
PDB Code
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Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5vmv
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Transcriptional regulator Kaiso
Ligand Name
double CpG-methylated DNA consensus binding site, MeCG2
EC.Number
E.C.-.-.-.-
Resolution
2.31(Å)
Affinity (Kd/Ki/IC50)
Kd=0.43nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Biochemistry Vol. 57: pp. 2109-2120
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q86T24
Entrez Gene ID
NCBI Entrez Gene ID:
10009
ASD
Information of known allosteric effects of PDB entries
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times since Nov 2007.
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娌狪CP澶2021015625鍙-3
娌叕缃戝畨澶囷細
姝ｅ湪鐢宠涓
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娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓