Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 28-APR-17 5VMZ TITLE KAISO (ZBTB33) E535Q MUTANT ZINC FINGER DNA BINDING DOMAIN IN COMPLEX TITLE 2 WITH A DOUBLE CPG-METHYLATED DNA RESEMBLING THE SPECIFIC KAISO TITLE 3 BINDING SEQUENCE (KBS) COMPND MOL_ID: 1; COMPND 2 MOLECULE: TRANSCRIPTIONAL REGULATOR KAISO; COMPND 3 CHAIN: A; COMPND 4 SYNONYM: ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 33; COMPND 5 ENGINEERED: YES; COMPND 6 MUTATION: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM) COMPND 9 P*GP*AP*AP*TP*AP*AP*CP*G)-3'); COMPND 10 CHAIN: D; COMPND 11 ENGINEERED: YES; COMPND 12 MOL_ID: 3; COMPND 13 MOLECULE: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM) COMPND 14 P*GP*GP*GP*AP*AP*GP*CP*A)-3'); COMPND 15 CHAIN: E; COMPND 16 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: ZBTB33, KAISO, ZNF348; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21(DE3); SOURCE 7 EXPRESSION_SYSTEM_TAXID: 469008; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3) [DNAY]; SOURCE 9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID; SOURCE 10 EXPRESSION_SYSTEM_PLASMID: PET21D; SOURCE 11 MOL_ID: 2; SOURCE 12 SYNTHETIC: YES; SOURCE 13 ORGANISM_SCIENTIFIC: UNIDENTIFIED; SOURCE 14 ORGANISM_TAXID: 32644; SOURCE 15 MOL_ID: 3; SOURCE 16 SYNTHETIC: YES; SOURCE 17 ORGANISM_SCIENTIFIC: UNIDENTIFIED; SOURCE 18 ORGANISM_TAXID: 32644 KEYWDS DNA METHYLATION, ZINC FINGER, TRANSCRIPTIONAL REGULATOR, KEYWDS 2 TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR E.N.NIKOLOVA,R.L.STANFIELD,M.A.MARTINEZ-YAMOUT,H.J.DYSON,P.E.WRIGHT REVDAT 2 25-APR-18 5VMZ 1 JRNL REVDAT 1 04-APR-18 5VMZ 0 JRNL AUTH E.N.NIKOLOVA,R.L.STANFIELD,H.J.DYSON,P.E.WRIGHT JRNL TITL CH···O HYDROGEN BONDS MEDIATE HIGHLY SPECIFIC JRNL TITL 2 RECOGNITION OF METHYLATED CPG SITES BY THE ZINC FINGER JRNL TITL 3 PROTEIN KAISO. JRNL REF BIOCHEMISTRY V. 57 2109 2018 JRNL REFN ISSN 1520-4995 JRNL PMID 29546986 JRNL DOI 10.1021/ACS.BIOCHEM.8B00065 REMARK 2 REMARK 2 RESOLUTION. 2.32 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX 1.9_1692 REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : NULL REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.32 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 45.24 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.370 REMARK 3 COMPLETENESS FOR RANGE (%) : 98.3 REMARK 3 NUMBER OF REFLECTIONS : 18646 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.170 REMARK 3 R VALUE (WORKING SET) : 0.167 REMARK 3 FREE R VALUE : 0.199 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 10.000 REMARK 3 FREE R VALUE TEST SET COUNT : 1864 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 45.2482 - 5.4493 0.99 1419 156 0.1572 0.1753 REMARK 3 2 5.4493 - 4.3264 1.00 1346 150 0.1370 0.1582 REMARK 3 3 4.3264 - 3.7798 1.00 1312 146 0.1381 0.1645 REMARK 3 4 3.7798 - 3.4344 1.00 1321 146 0.1608 0.1919 REMARK 3 5 3.4344 - 3.1883 1.00 1314 147 0.1784 0.2194 REMARK 3 6 3.1883 - 3.0003 1.00 1305 145 0.1867 0.2216 REMARK 3 7 3.0003 - 2.8501 1.00 1302 145 0.1973 0.2361 REMARK 3 8 2.8501 - 2.7261 1.00 1291 144 0.1985 0.2254 REMARK 3 9 2.7261 - 2.6211 0.99 1271 140 0.1892 0.2408 REMARK 3 10 2.6211 - 2.5307 1.00 1307 146 0.1868 0.2451 REMARK 3 11 2.5307 - 2.4516 0.98 1261 139 0.1964 0.2106 REMARK 3 12 2.4516 - 2.3815 0.97 1255 140 0.2186 0.2865 REMARK 3 13 2.3815 - 2.3188 0.85 1078 120 0.2192 0.2730 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : NULL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.210 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 21.440 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.009 1967 REMARK 3 ANGLE : 1.161 2790 REMARK 3 CHIRALITY : 0.050 290 REMARK 3 PLANARITY : 0.006 227 REMARK 3 DIHEDRAL : 25.761 744 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 9 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 481 THROUGH 496 ) REMARK 3 ORIGIN FOR THE GROUP (A): -20.5467 -4.9854 27.3697 REMARK 3 T TENSOR REMARK 3 T11: 0.8175 T22: 0.2819 REMARK 3 T33: 0.7333 T12: 0.0500 REMARK 3 T13: 0.0015 T23: 0.0231 REMARK 3 L TENSOR REMARK 3 L11: 8.0883 L22: 7.8145 REMARK 3 L33: 8.2163 L12: -7.8556 REMARK 3 L13: -3.8366 L23: 4.5833 REMARK 3 S TENSOR REMARK 3 S11: -0.0966 S12: -0.0598 S13: 0.6800 REMARK 3 S21: 0.1675 S22: 0.2003 S23: 0.1086 REMARK 3 S31: -0.3119 S32: -0.1060 S33: -0.0440 REMARK 3 TLS GROUP : 2 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 497 THROUGH 517 ) REMARK 3 ORIGIN FOR THE GROUP (A): -13.1019 -11.8581 23.2658 REMARK 3 T TENSOR REMARK 3 T11: 0.4940 T22: 0.2573 REMARK 3 T33: 0.6535 T12: -0.0328 REMARK 3 T13: -0.0490 T23: 0.0053 REMARK 3 L TENSOR REMARK 3 L11: 7.7113 L22: 7.0937 REMARK 3 L33: 7.0978 L12: -1.1894 REMARK 3 L13: -3.5038 L23: -1.6577 REMARK 3 S TENSOR REMARK 3 S11: 0.0916 S12: 0.1527 S13: 0.9717 REMARK 3 S21: 0.0398 S22: 0.1066 S23: -0.9377 REMARK 3 S31: -0.7847 S32: 0.1583 S33: -0.2036 REMARK 3 TLS GROUP : 3 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 518 THROUGH 552 ) REMARK 3 ORIGIN FOR THE GROUP (A): -5.8948 -30.5648 21.0571 REMARK 3 T TENSOR REMARK 3 T11: 0.2795 T22: 0.3335 REMARK 3 T33: 0.4476 T12: 0.0154 REMARK 3 T13: -0.0075 T23: 0.0235 REMARK 3 L TENSOR REMARK 3 L11: 8.4183 L22: 4.0894 REMARK 3 L33: 2.0672 L12: 3.2154 REMARK 3 L13: -2.0080 L23: -1.2837 REMARK 3 S TENSOR REMARK 3 S11: -0.0847 S12: -0.1891 S13: 0.1421 REMARK 3 S21: -0.3494 S22: -0.0600 S23: -1.1284 REMARK 3 S31: -0.2643 S32: 0.3183 S33: 0.1250 REMARK 3 TLS GROUP : 4 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 553 THROUGH 586 ) REMARK 3 ORIGIN FOR THE GROUP (A): -26.1150 -40.2864 21.5123 REMARK 3 T TENSOR REMARK 3 T11: 0.2101 T22: 0.2875 REMARK 3 T33: 0.3194 T12: 0.0667 REMARK 3 T13: 0.0463 T23: 0.0033 REMARK 3 L TENSOR REMARK 3 L11: 7.1981 L22: 4.8692 REMARK 3 L33: 6.7194 L12: 4.2734 REMARK 3 L13: 3.2730 L23: -0.7721 REMARK 3 S TENSOR REMARK 3 S11: 0.1145 S12: -0.4174 S13: 0.0229 REMARK 3 S21: 0.2809 S22: -0.1447 S23: 0.3610 REMARK 3 S31: -0.0897 S32: -0.5448 S33: 0.0150 REMARK 3 TLS GROUP : 5 REMARK 3 SELECTION: CHAIN 'A' AND (RESID 587 THROUGH 602 ) REMARK 3 ORIGIN FOR THE GROUP (A): -12.1481 -37.7525 32.5109 REMARK 3 T TENSOR REMARK 3 T11: 0.4074 T22: 0.3714 REMARK 3 T33: 0.3178 T12: 0.0685 REMARK 3 T13: -0.0743 T23: 0.0343 REMARK 3 L TENSOR REMARK 3 L11: 1.5771 L22: 3.3127 REMARK 3 L33: 2.1989 L12: 2.1665 REMARK 3 L13: -1.8678 L23: -2.4139 REMARK 3 S TENSOR REMARK 3 S11: -0.0764 S12: -0.5276 S13: 0.0946 REMARK 3 S21: 0.7363 S22: 0.3132 S23: -0.2703 REMARK 3 S31: -0.4070 S32: 0.2188 S33: -0.1716 REMARK 3 TLS GROUP : 6 REMARK 3 SELECTION: CHAIN 'D' AND (RESID 1 THROUGH 8 ) REMARK 3 ORIGIN FOR THE GROUP (A): -18.3343 -28.3251 11.9234 REMARK 3 T TENSOR REMARK 3 T11: 1.0037 T22: 0.4349 REMARK 3 T33: 0.3010 T12: -0.0799 REMARK 3 T13: -0.0870 T23: 0.0898 REMARK 3 L TENSOR REMARK 3 L11: 5.5591 L22: 2.2428 REMARK 3 L33: 8.5357 L12: -1.3860 REMARK 3 L13: 1.7481 L23: 3.3908 REMARK 3 S TENSOR REMARK 3 S11: 0.4489 S12: 0.6644 S13: -0.0872 REMARK 3 S21: -1.5288 S22: 0.3041 S23: -0.4410 REMARK 3 S31: 0.9682 S32: -0.3445 S33: -0.4717 REMARK 3 TLS GROUP : 7 REMARK 3 SELECTION: CHAIN 'D' AND (RESID 9 THROUGH 18 ) REMARK 3 ORIGIN FOR THE GROUP (A): -11.4112 -21.9390 39.1710 REMARK 3 T TENSOR REMARK 3 T11: 1.2104 T22: 0.8283 REMARK 3 T33: 0.6246 T12: -0.0256 REMARK 3 T13: -0.4629 T23: -0.0963 REMARK 3 L TENSOR REMARK 3 L11: 3.8036 L22: 0.4536 REMARK 3 L33: 2.9514 L12: -0.0291 REMARK 3 L13: -0.0565 L23: -1.0404 REMARK 3 S TENSOR REMARK 3 S11: -0.2739 S12: -1.1637 S13: 0.6870 REMARK 3 S21: 2.3388 S22: -0.0264 S23: -0.8676 REMARK 3 S31: -1.4775 S32: 0.8273 S33: 0.1601 REMARK 3 TLS GROUP : 8 REMARK 3 SELECTION: CHAIN 'E' AND (RESID 19 THROUGH 25 ) REMARK 3 ORIGIN FOR THE GROUP (A): -9.1128 -19.0541 45.1524 REMARK 3 T TENSOR REMARK 3 T11: 1.9927 T22: 1.3676 REMARK 3 T33: 0.7450 T12: -0.0337 REMARK 3 T13: -0.7614 T23: -0.2736 REMARK 3 L TENSOR REMARK 3 L11: 5.6118 L22: 4.7679 REMARK 3 L33: 3.3971 L12: -3.0161 REMARK 3 L13: 0.6743 L23: -3.5673 REMARK 3 S TENSOR REMARK 3 S11: -0.4131 S12: -2.5686 S13: 0.1618 REMARK 3 S21: 2.8553 S22: 0.3731 S23: -0.3131 REMARK 3 S31: -0.5062 S32: -0.3064 S33: 0.1860 REMARK 3 TLS GROUP : 9 REMARK 3 SELECTION: CHAIN 'E' AND (RESID 26 THROUGH 36 ) REMARK 3 ORIGIN FOR THE GROUP (A): -18.7444 -26.4043 17.6368 REMARK 3 T TENSOR REMARK 3 T11: 0.4505 T22: 0.2758 REMARK 3 T33: 0.2776 T12: -0.0077 REMARK 3 T13: -0.0282 T23: -0.0280 REMARK 3 L TENSOR REMARK 3 L11: 6.5780 L22: 5.4479 REMARK 3 L33: 8.8794 L12: -1.2905 REMARK 3 L13: -0.3488 L23: -0.4307 REMARK 3 S TENSOR REMARK 3 S11: -0.0377 S12: 0.8233 S13: 0.1025 REMARK 3 S21: -0.7997 S22: 0.1716 S23: 0.0075 REMARK 3 S31: -0.7637 S32: -0.2673 S33: -0.1000 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 5VMZ COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 01-MAY-17. REMARK 100 THE DEPOSITION ID IS D_1000227668. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 27-MAR-16 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 7.2 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRL REMARK 200 BEAMLINE : BL12-2 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.97946 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-2000 REMARK 200 DATA SCALING SOFTWARE : HKL-2000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 18669 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.319 REMARK 200 RESOLUTION RANGE LOW (A) : 45.240 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 98.4 REMARK 200 DATA REDUNDANCY : 6.500 REMARK 200 R MERGE (I) : 0.06340 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 18.9000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.32 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.40 REMARK 200 COMPLETENESS FOR SHELL (%) : 87.8 REMARK 200 DATA REDUNDANCY IN SHELL : 5.50 REMARK 200 R MERGE FOR SHELL (I) : 0.30900 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 4.530 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHENIX 1.9_1692 REMARK 200 STARTING MODEL: 4F6N REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 68.29 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.88 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1 M DISODIUM TARTRATE, 20 % PEG REMARK 280 3350, PH 7.2, VAPOR DIFFUSION, SITTING DROP, TEMPERATURE 295K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 2 2 2 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,-Y,Z REMARK 290 3555 -X,Y,-Z REMARK 290 4555 X,-Y,-Z REMARK 290 5555 X+1/2,Y+1/2,Z REMARK 290 6555 -X+1/2,-Y+1/2,Z REMARK 290 7555 -X+1/2,Y+1/2,-Z REMARK 290 8555 X+1/2,-Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 3 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 4 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 22.20450 REMARK 290 SMTRY2 5 0.000000 1.000000 0.000000 91.74350 REMARK 290 SMTRY3 5 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 6 -1.000000 0.000000 0.000000 22.20450 REMARK 290 SMTRY2 6 0.000000 -1.000000 0.000000 91.74350 REMARK 290 SMTRY3 6 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 7 -1.000000 0.000000 0.000000 22.20450 REMARK 290 SMTRY2 7 0.000000 1.000000 0.000000 91.74350 REMARK 290 SMTRY3 7 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 8 1.000000 0.000000 0.000000 22.20450 REMARK 290 SMTRY2 8 0.000000 -1.000000 0.000000 91.74350 REMARK 290 SMTRY3 8 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 8000 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 11270 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -7.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, D, E REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 CL CL A 704 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 471 REMARK 465 ALA A 472 REMARK 465 ASN A 473 REMARK 465 LYS A 474 REMARK 465 ARG A 475 REMARK 465 MET A 476 REMARK 465 LYS A 477 REMARK 465 VAL A 478 REMARK 465 LYS A 479 REMARK 465 HIS A 480 REMARK 465 ARG A 603 REMARK 465 SER A 604 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DG D 11 O4' - C1' - N9 ANGL. DEV. = 2.0 DEGREES REMARK 500 DT D 14 O4' - C1' - N1 ANGL. DEV. = 2.1 DEGREES REMARK 500 DG E 30 O4' - C1' - N9 ANGL. DEV. = 3.5 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASP A 482 -7.21 -140.20 REMARK 500 CYS A 527 -159.44 -143.84 REMARK 500 SER A 581 -59.30 -138.97 REMARK 500 LYS A 582 70.41 64.75 REMARK 500 REMARK 500 REMARK: NULL REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 701 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 496 SG REMARK 620 2 CYS A 499 SG 115.3 REMARK 620 3 HIS A 512 NE2 105.4 105.6 REMARK 620 4 HIS A 516 NE2 110.6 112.2 107.0 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 702 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 524 SG REMARK 620 2 CYS A 527 SG 117.2 REMARK 620 3 HIS A 540 NE2 105.9 112.3 REMARK 620 4 HIS A 544 NE2 103.0 114.4 102.5 REMARK 620 N 1 2 3 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 ZN A 703 ZN REMARK 620 N RES CSSEQI ATOM REMARK 620 1 CYS A 552 SG REMARK 620 2 CYS A 555 SG 116.7 REMARK 620 3 HIS A 568 NE2 112.7 108.3 REMARK 620 4 HIS A 573 NE2 103.7 110.3 104.3 REMARK 620 N 1 2 3 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 701 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 702 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue ZN A 703 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue CL A 704 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue TLA A 705 REMARK 900 REMARK 900 RELATED ENTRIES REMARK 900 RELATED ID: 5VMU RELATED DB: PDB REMARK 900 RELATED ID: 5VMV RELATED DB: PDB REMARK 900 RELATED ID: 5VMW RELATED DB: PDB REMARK 900 RELATED ID: 5VMX RELATED DB: PDB REMARK 900 RELATED ID: 5VMY RELATED DB: PDB DBREF 5VMZ A 471 604 UNP Q86T24 KAISO_HUMAN 471 604 DBREF 5VMZ D 1 18 PDB 5VMZ 5VMZ 1 18 DBREF 5VMZ E 19 36 PDB 5VMZ 5VMZ 19 36 SEQADV 5VMZ GLN A 535 UNP Q86T24 GLU 535 ENGINEERED MUTATION SEQRES 1 A 134 MET ALA ASN LYS ARG MET LYS VAL LYS HIS ASP ASP HIS SEQRES 2 A 134 TYR GLU LEU ILE VAL ASP GLY ARG VAL TYR TYR ILE CYS SEQRES 3 A 134 ILE VAL CYS LYS ARG SER TYR VAL CYS LEU THR SER LEU SEQRES 4 A 134 ARG ARG HIS PHE ASN ILE HIS SER TRP GLU LYS LYS TYR SEQRES 5 A 134 PRO CYS ARG TYR CYS GLU LYS VAL PHE PRO LEU ALA GLN SEQRES 6 A 134 TYR ARG THR LYS HIS GLU ILE HIS HIS THR GLY GLU ARG SEQRES 7 A 134 ARG TYR GLN CYS LEU ALA CYS GLY LYS SER PHE ILE ASN SEQRES 8 A 134 TYR GLN PHE MET SER SER HIS ILE LYS SER VAL HIS SER SEQRES 9 A 134 GLN ASP PRO SER GLY ASP SER LYS LEU TYR ARG LEU HIS SEQRES 10 A 134 PRO CYS ARG SER LEU GLN ILE ARG GLN TYR ALA TYR LEU SEQRES 11 A 134 SER ASP ARG SER SEQRES 1 D 18 DT DG DC DT DT DC DC 5CM DG 5CM DG DA DA SEQRES 2 D 18 DT DA DA DC DG SEQRES 1 E 18 DC DG DT DT DA DT DT 5CM DG 5CM DG DG DG SEQRES 2 E 18 DA DA DG DC DA HET 5CM D 8 20 HET 5CM D 10 20 HET 5CM E 26 20 HET 5CM E 28 20 HET ZN A 701 1 HET ZN A 702 1 HET ZN A 703 1 HET CL A 704 1 HET TLA A 705 10 HETNAM 5CM 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE HETNAM ZN ZINC ION HETNAM CL CHLORIDE ION HETNAM TLA L(+)-TARTARIC ACID FORMUL 2 5CM 4(C10 H16 N3 O7 P) FORMUL 4 ZN 3(ZN 2+) FORMUL 7 CL CL 1- FORMUL 8 TLA C4 H6 O6 FORMUL 9 HOH *84(H2 O) HELIX 1 AA1 CYS A 505 TRP A 518 1 14 HELIX 2 AA2 LEU A 533 GLY A 546 1 14 HELIX 3 AA3 ASN A 561 SER A 574 1 14 HELIX 4 AA4 TYR A 597 ASP A 602 5 6 SHEET 1 AA1 3 HIS A 483 VAL A 488 0 SHEET 2 AA1 3 ARG A 491 CYS A 496 -1 O ILE A 495 N TYR A 484 SHEET 3 AA1 3 SER A 502 TYR A 503 -1 O TYR A 503 N TYR A 494 SHEET 1 AA2 2 TYR A 522 PRO A 523 0 SHEET 2 AA2 2 VAL A 530 PHE A 531 -1 O PHE A 531 N TYR A 522 SHEET 1 AA3 3 SER A 558 PHE A 559 0 SHEET 2 AA3 3 TYR A 550 CYS A 552 -1 N TYR A 550 O PHE A 559 SHEET 3 AA3 3 TYR A 584 LEU A 586 -1 O ARG A 585 N GLN A 551 LINK SG CYS A 496 ZN ZN A 701 1555 1555 2.27 LINK SG CYS A 499 ZN ZN A 701 1555 1555 2.21 LINK NE2 HIS A 512 ZN ZN A 701 1555 1555 2.05 LINK NE2 HIS A 516 ZN ZN A 701 1555 1555 2.01 LINK SG CYS A 524 ZN ZN A 702 1555 1555 2.20 LINK SG CYS A 527 ZN ZN A 702 1555 1555 2.29 LINK NE2 HIS A 540 ZN ZN A 702 1555 1555 1.99 LINK NE2 HIS A 544 ZN ZN A 702 1555 1555 2.05 LINK SG CYS A 552 ZN ZN A 703 1555 1555 2.21 LINK SG CYS A 555 ZN ZN A 703 1555 1555 2.34 LINK NE2 HIS A 568 ZN ZN A 703 1555 1555 2.04 LINK NE2 HIS A 573 ZN ZN A 703 1555 1555 2.13 LINK O3' DC D 7 P 5CM D 8 1555 1555 1.60 LINK O3' 5CM D 8 P DG D 9 1555 1555 1.61 LINK O3' DG D 9 P 5CM D 10 1555 1555 1.61 LINK O3' 5CM D 10 P DG D 11 1555 1555 1.60 LINK O3' DT E 25 P 5CM E 26 1555 1555 1.60 LINK O3' 5CM E 26 P DG E 27 1555 1555 1.61 LINK O3' DG E 27 P 5CM E 28 1555 1555 1.61 LINK O3' 5CM E 28 P DG E 29 1555 1555 1.61 SITE 1 AC1 4 CYS A 496 CYS A 499 HIS A 512 HIS A 516 SITE 1 AC2 4 CYS A 524 CYS A 527 HIS A 540 HIS A 544 SITE 1 AC3 4 CYS A 552 CYS A 555 HIS A 568 HIS A 573 SITE 1 AC4 3 ARG A 548 ARG A 590 HOH A 827 SITE 1 AC5 15 LYS A 539 TYR A 550 ASN A 561 TYR A 562 SITE 2 AC5 15 GLN A 563 HOH A 801 HOH A 815 HOH A 816 SITE 3 AC5 15 HOH A 821 HOH A 828 HOH A 829 DC D 6 SITE 4 AC5 15 DC D 7 DG E 30 HOH E 106 CRYST1 44.409 183.487 104.003 90.00 90.00 90.00 C 2 2 2 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.022518 0.000000 0.000000 0.00000 SCALE2 0.000000 0.005450 0.000000 0.00000 SCALE3 0.000000 0.000000 0.009615 0.00000 ATOM 1 N ASP A 481 -7.607 -0.748 26.851 1.00109.75 N ANISOU 1 N ASP A 481 12891 10138 18669 -1587 819 -3202 N ATOM 2 CA ASP A 481 -8.103 -1.989 27.437 1.00112.14 C ANISOU 2 CA ASP A 481 13512 11043 18052 -1043 257 -3091 C ATOM 3 C ASP A 481 -8.044 -3.141 26.420 1.00105.67 C ANISOU 3 C ASP A 481 12968 10486 16698 -897 319 -2463 C ATOM 4 O ASP A 481 -7.110 -3.223 25.625 1.00114.58 O ANISOU 4 O ASP A 481 13818 11648 18068 -1101 590 -2454 O ATOM 5 CB ASP A 481 -9.532 -1.790 27.951 1.00115.60 C ANISOU 5 CB ASP A 481 14448 11297 18178 -816 121 -2760 C ATOM 6 CG ASP A 481 -9.899 -2.762 29.064 1.00120.11 C ANISOU 6 CG ASP A 481 15213 12400 18022 -267 -393 -2942 C ATOM 7 OD1 ASP A 481 -9.274 -3.845 29.147 1.00124.81 O ANISOU 7 OD1 ASP A 481 15772 13483 18167 9 -610 -3043 O ATOM 8 OD2 ASP A 481 -10.816 -2.444 29.851 1.00116.54 O ANISOU 8 OD2 ASP A 481 14992 11860 17427 -63 -525 -2950 O ATOM 9 N ASP A 482 -9.030 -4.037 26.464 1.00 86.49 N ANISOU 9 N ASP A 482 11051 8229 13584 -546 94 -1991 N ATOM 10 CA ASP A 482 -9.198 -5.069 25.440 1.00 79.99 C ANISOU 10 CA ASP A 482 10534 7559 12301 -415 151 -1408 C ATOM 11 C ASP A 482 -10.684 -5.265 25.113 1.00 73.68 C ANISOU 11 C ASP A 482 10236 6564 11196 -287 160 -830 C ATOM 12 O ASP A 482 -11.050 -5.995 24.187 1.00 63.11 O ANISOU 12 O ASP A 482 9147 5292 9538 -178 196 -387 O ATOM 13 CB ASP A 482 -8.574 -6.395 25.887 1.00 74.00 C ANISOU 13 CB ASP A 482 9767 7361 10987 -53 -205 -1644 C ATOM 14 CG ASP A 482 -9.306 -7.022 27.056 1.00 70.97 C ANISOU 14 CG ASP A 482 9699 7154 10114 352 -525 -1734 C ATOM 15 OD1 ASP A 482 -9.875 -6.274 27.883 1.00 81.72 O ANISOU 15 OD1 ASP A 482 11059 8347 11645 356 -576 -1926 O ATOM 16 OD2 ASP A 482 -9.304 -8.268 27.152 1.00 58.45 O ANISOU 16 OD2 ASP A 482 8392 5843 7973 698 -670 -1597 O ATOM 17 N HIS A 483 -11.535 -4.606 25.890 1.00 56.88 N ANISOU 17 N HIS A 483 8201 4229 9182 -274 104 -916 N ATOM 18 CA HIS A 483 -12.971 -4.619 25.651 1.00 62.81 C ANISOU 18 CA HIS A 483 9311 4812 9741 -169 126 -477 C ATOM 19 C HIS A 483 -13.596 -3.302 26.068 1.00 64.98 C ANISOU 19 C HIS A 483 9592 4712 10387 -268 253 -541 C ATOM 20 O HIS A 483 -12.961 -2.505 26.758 1.00 63.75 O ANISOU 20 O HIS A 483 9177 4428 10618 -408 266 -999 O ATOM 21 CB HIS A 483 -13.642 -5.732 26.426 1.00 51.21 C ANISOU 21 CB HIS A 483 8054 3606 7796 112 -133 -482 C ATOM 22 CG HIS A 483 -13.712 -5.467 27.894 1.00 52.45 C ANISOU 22 CG HIS A 483 8172 3836 7920 288 -298 -882 C ATOM 23 ND1 HIS A 483 -12.625 -5.624 28.727 1.00 62.57 N ANISOU 23 ND1 HIS A 483 9245 5403 9125 458 -493 -1396 N ATOM 24 CD2 HIS A 483 -14.731 -5.046 28.676 1.00 61.87 C ANISOU 24 CD2 HIS A 483 9500 4909 9099 406 -315 -880 C ATOM 25 CE1 HIS A 483 -12.974 -5.312 29.962 1.00 67.99 C ANISOU 25 CE1 HIS A 483 9973 6148 9714 722 -638 -1695 C ATOM 26 NE2 HIS A 483 -14.245 -4.949 29.958 1.00 63.20 N ANISOU 26 NE2 HIS A 483 9583 5275 9155 672 -508 -1360 N ATOM 27 N TYR A 484 -14.838 -3.088 25.643 1.00 54.51 N ANISOU 27 N TYR A 484 8533 3230 8950 -165 324 -151 N ATOM 28 CA TYR A 484 -15.699 -2.095 26.260 1.00 62.36 C ANISOU 28 CA TYR A 484 9607 3963 10125 -127 354 -208 C ATOM 29 C TYR A 484 -17.013 -2.776 26.635 1.00 69.45 C ANISOU 29 C TYR A 484 10680 5065 10642 110 167 -55 C ATOM 30 O TYR A 484 -17.304 -3.875 26.150 1.00 72.62 O ANISOU 30 O TYR A 484 11147 5699 10746 186 89 132 O ATOM 31 CB TYR A 484 -15.923 -0.889 25.338 1.00 67.60 C ANISOU 31 CB TYR A 484 10403 4173 11110 -191 729 94 C ATOM 32 CG TYR A 484 -16.616 -1.169 24.017 1.00 68.53 C ANISOU 32 CG TYR A 484 10771 4346 10922 41 841 620 C ATOM 33 CD1 TYR A 484 -18.002 -1.140 23.922 1.00 62.71 C ANISOU 33 CD1 TYR A 484 10206 3693 9927 325 715 797 C ATOM 34 CD2 TYR A 484 -15.883 -1.406 22.852 1.00 66.26 C ANISOU 34 CD2 TYR A 484 10517 4064 10596 43 1068 887 C ATOM 35 CE1 TYR A 484 -18.651 -1.371 22.714 1.00 59.47 C ANISOU 35 CE1 TYR A 484 9963 3423 9209 642 737 1141 C ATOM 36 CE2 TYR A 484 -16.522 -1.635 21.633 1.00 60.78 C ANISOU 36 CE2 TYR A 484 10065 3486 9543 397 1122 1306 C ATOM 37 CZ TYR A 484 -17.911 -1.615 21.574 1.00 65.27 C ANISOU 37 CZ TYR A 484 10771 4183 9843 715 920 1390 C ATOM 38 OH TYR A 484 -18.577 -1.842 20.384 1.00 66.29 O ANISOU 38 OH TYR A 484 11078 4525 9585 1165 883 1667 O ATOM 39 N GLU A 485 -17.784 -2.152 27.524 1.00 66.82 N ANISOU 39 N GLU A 485 10391 4631 10365 215 123 -182 N ATOM 40 CA GLU A 485 -19.068 -2.711 27.941 1.00 55.14 C ANISOU 40 CA GLU A 485 9016 3317 8617 411 41 -61 C ATOM 41 C GLU A 485 -20.233 -2.002 27.284 1.00 66.24 C ANISOU 41 C GLU A 485 10504 4587 10075 513 131 189 C ATOM 42 O GLU A 485 -20.161 -0.823 26.908 1.00 76.70 O ANISOU 42 O GLU A 485 11905 5611 11625 516 275 253 O ATOM 43 CB GLU A 485 -19.265 -2.636 29.456 1.00 54.31 C ANISOU 43 CB GLU A 485 8921 3289 8425 590 -55 -351 C ATOM 44 CG GLU A 485 -18.215 -3.303 30.310 1.00 70.68 C ANISOU 44 CG GLU A 485 10952 5587 10315 703 -189 -666 C ATOM 45 CD GLU A 485 -18.519 -3.140 31.793 1.00 85.88 C ANISOU 45 CD GLU A 485 12954 7627 12052 1057 -275 -937 C ATOM 46 OE1 GLU A 485 -19.617 -2.634 32.121 1.00 85.26 O ANISOU 46 OE1 GLU A 485 12952 7444 11997 1155 -197 -825 O ATOM 47 OE2 GLU A 485 -17.664 -3.511 32.626 1.00 97.81 O ANISOU 47 OE2 GLU A 485 14449 9375 13339 1318 -430 -1280 O ATOM 48 N LEU A 486 -21.332 -2.731 27.202 1.00 60.89 N ANISOU 48 N LEU A 486 9805 4120 9210 626 78 288 N ATOM 49 CA LEU A 486 -22.543 -2.240 26.594 1.00 61.92 C ANISOU 49 CA LEU A 486 9934 4271 9322 817 87 425 C ATOM 50 C LEU A 486 -23.671 -2.696 27.503 1.00 59.51 C ANISOU 50 C LEU A 486 9511 4128 8971 889 75 307 C ATOM 51 O LEU A 486 -23.653 -3.816 27.974 1.00 57.71 O ANISOU 51 O LEU A 486 9225 4018 8683 787 111 248 O ATOM 52 CB LEU A 486 -22.662 -2.788 25.175 1.00 67.70 C ANISOU 52 CB LEU A 486 10635 5170 9917 894 34 581 C ATOM 53 CG LEU A 486 -23.745 -2.386 24.189 1.00 82.98 C ANISOU 53 CG LEU A 486 12552 7253 11723 1246 -30 666 C ATOM 54 CD1 LEU A 486 -23.163 -2.466 22.791 1.00 84.33 C ANISOU 54 CD1 LEU A 486 12847 7473 11720 1420 -19 866 C ATOM 55 CD2 LEU A 486 -24.899 -3.347 24.322 1.00 89.73 C ANISOU 55 CD2 LEU A 486 13102 8429 12563 1253 -178 431 C ATOM 56 N ILE A 487 -24.625 -1.825 27.804 1.00 65.54 N ANISOU 56 N ILE A 487 10267 4865 9770 1089 92 290 N ATOM 57 CA ILE A 487 -25.716 -2.237 28.675 1.00 60.88 C ANISOU 57 CA ILE A 487 9526 4437 9170 1160 159 188 C ATOM 58 C ILE A 487 -27.056 -1.907 28.050 1.00 68.91 C ANISOU 58 C ILE A 487 10342 5645 10196 1372 108 161 C ATOM 59 O ILE A 487 -27.371 -0.738 27.801 1.00 68.01 O ANISOU 59 O ILE A 487 10343 5457 10042 1639 60 212 O ATOM 60 CB ILE A 487 -25.643 -1.575 30.062 1.00 63.17 C ANISOU 60 CB ILE A 487 9948 4609 9446 1289 219 89 C ATOM 61 CG1 ILE A 487 -24.239 -1.706 30.651 1.00 62.78 C ANISOU 61 CG1 ILE A 487 10047 4445 9360 1197 176 -20 C ATOM 62 CG2 ILE A 487 -26.665 -2.203 30.999 1.00 55.98 C ANISOU 62 CG2 ILE A 487 8915 3863 8493 1385 406 55 C ATOM 63 CD1 ILE A 487 -24.067 -0.969 31.952 1.00 55.80 C ANISOU 63 CD1 ILE A 487 9270 3495 8436 1419 144 -243 C ATOM 64 N VAL A 488 -27.833 -2.951 27.780 1.00 68.49 N ANISOU 64 N VAL A 488 9974 5829 10218 1279 131 31 N ATOM 65 CA VAL A 488 -29.207 -2.786 27.337 1.00 71.50 C ANISOU 65 CA VAL A 488 10013 6500 10655 1491 56 -158 C ATOM 66 C VAL A 488 -30.109 -3.465 28.342 1.00 74.56 C ANISOU 66 C VAL A 488 10107 6957 11265 1338 324 -313 C ATOM 67 O VAL A 488 -29.871 -4.620 28.694 1.00 78.36 O ANISOU 67 O VAL A 488 10539 7337 11899 1032 549 -325 O ATOM 68 CB VAL A 488 -29.457 -3.396 25.950 1.00 68.45 C ANISOU 68 CB VAL A 488 9371 6383 10255 1546 -165 -334 C ATOM 69 CG1 VAL A 488 -30.778 -2.883 25.391 1.00 65.13 C ANISOU 69 CG1 VAL A 488 8608 6345 9792 1956 -352 -605 C ATOM 70 CG2 VAL A 488 -28.316 -3.075 25.010 1.00 59.55 C ANISOU 70 CG2 VAL A 488 8595 5133 8898 1649 -294 -93 C ATOM 71 N ASP A 489 -31.132 -2.750 28.801 1.00 68.48 N ANISOU 71 N ASP A 489 9175 6330 10512 1584 366 -404 N ATOM 72 CA ASP A 489 -32.103 -3.293 29.749 1.00 82.84 C ANISOU 72 CA ASP A 489 10680 8223 12574 1477 718 -533 C ATOM 73 C ASP A 489 -31.424 -3.932 30.956 1.00 83.93 C ANISOU 73 C ASP A 489 11130 8065 12694 1303 1093 -306 C ATOM 74 O ASP A 489 -31.843 -4.993 31.420 1.00 87.22 O ANISOU 74 O ASP A 489 11364 8411 13363 1076 1513 -337 O ATOM 75 CB ASP A 489 -33.001 -4.331 29.067 1.00 94.19 C ANISOU 75 CB ASP A 489 11510 9890 14390 1242 780 -908 C ATOM 76 CG ASP A 489 -33.441 -3.907 27.680 1.00102.35 C ANISOU 76 CG ASP A 489 12260 11300 15327 1528 306 -1204 C ATOM 77 OD1 ASP A 489 -33.836 -2.733 27.503 1.00106.51 O ANISOU 77 OD1 ASP A 489 12867 12012 15588 1993 85 -1184 O ATOM 78 OD2 ASP A 489 -33.391 -4.755 26.764 1.00106.93 O ANISOU 78 OD2 ASP A 489 12574 11997 16057 1365 157 -1469 O ATOM 79 N GLY A 490 -30.355 -3.309 31.439 1.00 78.39 N ANISOU 79 N GLY A 490 10900 7179 11705 1446 971 -113 N ATOM 80 CA GLY A 490 -29.615 -3.856 32.560 1.00 81.62 C ANISOU 80 CA GLY A 490 11635 7408 11968 1458 1232 38 C ATOM 81 C GLY A 490 -28.698 -5.004 32.172 1.00 87.31 C ANISOU 81 C GLY A 490 12474 8005 12695 1194 1280 104 C ATOM 82 O GLY A 490 -27.716 -5.271 32.865 1.00 86.62 O ANISOU 82 O GLY A 490 12735 7813 12366 1309 1333 202 O ATOM 83 N ARG A 491 -29.016 -5.692 31.076 1.00 89.36 N ANISOU 83 N ARG A 491 12435 8317 13200 911 1231 -7 N ATOM 84 CA ARG A 491 -28.147 -6.749 30.559 1.00 88.80 C ANISOU 84 CA ARG A 491 12480 8130 13130 681 1230 30 C ATOM 85 C ARG A 491 -26.787 -6.172 30.200 1.00 80.29 C ANISOU 85 C ARG A 491 11699 7036 11772 763 870 114 C ATOM 86 O ARG A 491 -26.681 -5.252 29.394 1.00 82.20 O ANISOU 86 O ARG A 491 11891 7353 11991 824 564 85 O ATOM 87 CB ARG A 491 -28.761 -7.429 29.332 1.00 91.03 C ANISOU 87 CB ARG A 491 12345 8517 13725 424 1138 -213 C ATOM 88 CG ARG A 491 -30.078 -8.125 29.590 1.00102.60 C ANISOU 88 CG ARG A 491 13373 9970 15638 231 1535 -433 C ATOM 89 CD ARG A 491 -29.859 -9.412 30.359 1.00108.86 C ANISOU 89 CD ARG A 491 14374 10399 16590 28 2122 -283 C ATOM 90 NE ARG A 491 -28.899 -10.279 29.682 1.00109.63 N ANISOU 90 NE ARG A 491 14667 10365 16623 -129 1994 -271 N ATOM 91 CZ ARG A 491 -28.531 -11.474 30.130 1.00109.74 C ANISOU 91 CZ ARG A 491 14952 10027 16717 -255 2461 -131 C ATOM 92 NH1 ARG A 491 -27.650 -12.200 29.451 1.00102.33 N ANISOU 92 NH1 ARG A 491 14193 9006 15683 -349 2288 -143 N ATOM 93 NH2 ARG A 491 -29.048 -11.945 31.258 1.00114.68 N ANISOU 93 NH2 ARG A 491 15715 10366 17492 -229 3155 51 N ATOM 94 N VAL A 492 -25.745 -6.718 30.805 1.00 73.13 N ANISOU 94 N VAL A 492 11101 6025 10660 806 958 209 N ATOM 95 CA VAL A 492 -24.400 -6.248 30.552 1.00 62.23 C ANISOU 95 CA VAL A 492 9904 4649 9092 847 661 200 C ATOM 96 C VAL A 492 -23.705 -7.114 29.520 1.00 62.32 C ANISOU 96 C VAL A 492 9905 4671 9104 645 563 223 C ATOM 97 O VAL A 492 -23.665 -8.335 29.646 1.00 59.99 O ANISOU 97 O VAL A 492 9688 4315 8792 578 773 262 O ATOM 98 CB VAL A 492 -23.584 -6.231 31.843 1.00 60.51 C ANISOU 98 CB VAL A 492 9971 4430 8591 1133 714 164 C ATOM 99 CG1 VAL A 492 -22.112 -5.986 31.544 1.00 54.40 C ANISOU 99 CG1 VAL A 492 9263 3698 7709 1118 428 36 C ATOM 100 CG2 VAL A 492 -24.149 -5.168 32.786 1.00 56.58 C ANISOU 100 CG2 VAL A 492 9490 3948 8059 1398 720 84 C ATOM 101 N TYR A 493 -23.162 -6.483 28.487 1.00 63.70 N ANISOU 101 N TYR A 493 10022 4885 9295 583 301 223 N ATOM 102 CA TYR A 493 -22.409 -7.220 27.484 1.00 61.11 C ANISOU 102 CA TYR A 493 9704 4605 8911 462 196 254 C ATOM 103 C TYR A 493 -21.000 -6.678 27.391 1.00 58.44 C ANISOU 103 C TYR A 493 9478 4254 8474 475 72 260 C ATOM 104 O TYR A 493 -20.779 -5.480 27.539 1.00 61.64 O ANISOU 104 O TYR A 493 9877 4568 8974 510 32 230 O ATOM 105 CB TYR A 493 -23.096 -7.145 26.124 1.00 59.63 C ANISOU 105 CB TYR A 493 9312 4529 8817 446 54 240 C ATOM 106 CG TYR A 493 -24.508 -7.642 26.169 1.00 56.59 C ANISOU 106 CG TYR A 493 8664 4206 8631 404 144 77 C ATOM 107 CD1 TYR A 493 -24.786 -8.998 26.081 1.00 57.65 C ANISOU 107 CD1 TYR A 493 8693 4299 8913 219 281 -57 C ATOM 108 CD2 TYR A 493 -25.567 -6.759 26.326 1.00 56.06 C ANISOU 108 CD2 TYR A 493 8426 4215 8659 541 132 13 C ATOM 109 CE1 TYR A 493 -26.082 -9.464 26.140 1.00 60.47 C ANISOU 109 CE1 TYR A 493 8708 4669 9598 101 435 -298 C ATOM 110 CE2 TYR A 493 -26.866 -7.212 26.386 1.00 58.62 C ANISOU 110 CE2 TYR A 493 8401 4641 9231 484 232 -218 C ATOM 111 CZ TYR A 493 -27.117 -8.568 26.293 1.00 65.60 C ANISOU 111 CZ TYR A 493 9112 5463 10352 227 400 -397 C ATOM 112 OH TYR A 493 -28.407 -9.025 26.346 1.00 76.69 O ANISOU 112 OH TYR A 493 10070 6925 12142 94 564 -716 O ATOM 113 N TYR A 494 -20.051 -7.579 27.171 1.00 55.97 N ANISOU 113 N TYR A 494 9242 4007 8015 440 44 257 N ATOM 114 CA TYR A 494 -18.659 -7.213 26.973 1.00 48.09 C ANISOU 114 CA TYR A 494 8248 3052 6974 423 -55 197 C ATOM 115 C TYR A 494 -18.318 -7.392 25.506 1.00 46.15 C ANISOU 115 C TYR A 494 7952 2856 6727 344 -104 342 C ATOM 116 O TYR A 494 -18.565 -8.460 24.928 1.00 54.46 O ANISOU 116 O TYR A 494 9031 3996 7665 349 -137 385 O ATOM 117 CB TYR A 494 -17.747 -8.063 27.860 1.00 48.56 C ANISOU 117 CB TYR A 494 8431 3237 6782 574 -68 52 C ATOM 118 CG TYR A 494 -18.186 -8.066 29.301 1.00 50.43 C ANISOU 118 CG TYR A 494 8804 3469 6890 819 22 -46 C ATOM 119 CD1 TYR A 494 -17.879 -7.003 30.153 1.00 51.00 C ANISOU 119 CD1 TYR A 494 8805 3564 7009 951 -83 -295 C ATOM 120 CD2 TYR A 494 -18.928 -9.117 29.808 1.00 48.75 C ANISOU 120 CD2 TYR A 494 8797 3193 6533 944 262 95 C ATOM 121 CE1 TYR A 494 -18.300 -7.009 31.483 1.00 50.75 C ANISOU 121 CE1 TYR A 494 8933 3580 6771 1298 -12 -388 C ATOM 122 CE2 TYR A 494 -19.349 -9.132 31.121 1.00 50.12 C ANISOU 122 CE2 TYR A 494 9155 3353 6536 1258 443 80 C ATOM 123 CZ TYR A 494 -19.035 -8.084 31.955 1.00 51.93 C ANISOU 123 CZ TYR A 494 9338 3690 6702 1481 275 -154 C ATOM 124 OH TYR A 494 -19.471 -8.136 33.259 1.00 54.21 O ANISOU 124 OH TYR A 494 9849 4014 6735 1908 453 -163 O ATOM 125 N ILE A 495 -17.753 -6.349 24.913 1.00 46.80 N ANISOU 125 N ILE A 495 7979 2848 6953 300 -63 406 N ATOM 126 CA ILE A 495 -17.508 -6.317 23.479 1.00 55.77 C ANISOU 126 CA ILE A 495 9130 4020 8040 346 -28 619 C ATOM 127 C ILE A 495 -16.019 -6.249 23.201 1.00 60.03 C ANISOU 127 C ILE A 495 9610 4574 8625 248 64 602 C ATOM 128 O ILE A 495 -15.307 -5.370 23.703 1.00 55.69 O ANISOU 128 O ILE A 495 8948 3863 8350 105 189 458 O ATOM 129 CB ILE A 495 -18.195 -5.116 22.786 1.00 63.84 C ANISOU 129 CB ILE A 495 10212 4876 9167 484 97 822 C ATOM 130 CG1 ILE A 495 -19.703 -5.335 22.668 1.00 67.97 C ANISOU 130 CG1 ILE A 495 10710 5524 9589 665 -47 796 C ATOM 131 CG2 ILE A 495 -17.647 -4.947 21.386 1.00 67.89 C ANISOU 131 CG2 ILE A 495 10819 5405 9569 647 237 1089 C ATOM 132 CD1 ILE A 495 -20.459 -5.197 23.950 1.00 69.89 C ANISOU 132 CD1 ILE A 495 10890 5705 9960 581 -63 624 C ATOM 133 N CYS A 496 -15.561 -7.200 22.400 1.00 58.99 N ANISOU 133 N CYS A 496 9507 4642 8263 322 2 684 N ATOM 134 CA CYS A 496 -14.184 -7.252 21.964 1.00 56.33 C ANISOU 134 CA CYS A 496 9079 4385 7940 268 108 684 C ATOM 135 C CYS A 496 -13.813 -5.983 21.209 1.00 56.32 C ANISOU 135 C CYS A 496 9053 4132 8214 221 458 903 C ATOM 136 O CYS A 496 -14.523 -5.580 20.294 1.00 59.11 O ANISOU 136 O CYS A 496 9587 4401 8472 437 572 1209 O ATOM 137 CB CYS A 496 -13.979 -8.475 21.083 1.00 49.61 C ANISOU 137 CB CYS A 496 8317 3789 6742 438 -21 779 C ATOM 138 SG CYS A 496 -12.319 -8.669 20.514 1.00 59.25 S ANISOU 138 SG CYS A 496 9406 5185 7922 429 113 784 S ATOM 139 N ILE A 497 -12.704 -5.357 21.582 1.00 56.75 N ANISOU 139 N ILE A 497 8021 3199 10344 -492 604 724 N ATOM 140 CA ILE A 497 -12.284 -4.125 20.916 1.00 67.89 C ANISOU 140 CA ILE A 497 9513 4253 12030 -559 951 953 C ATOM 141 C ILE A 497 -11.927 -4.369 19.451 1.00 71.99 C ANISOU 141 C ILE A 497 9898 4939 12517 -507 1226 1406 C ATOM 142 O ILE A 497 -12.193 -3.523 18.589 1.00 79.11 O ANISOU 142 O ILE A 497 10922 5735 13402 -330 1540 1787 O ATOM 143 CB ILE A 497 -11.085 -3.470 21.630 1.00 71.99 C ANISOU 143 CB ILE A 497 9958 4502 12892 -974 883 580 C ATOM 144 CG1 ILE A 497 -11.544 -2.828 22.937 1.00 84.84 C ANISOU 144 CG1 ILE A 497 11859 5886 14489 -988 720 189 C ATOM 145 CG2 ILE A 497 -10.456 -2.394 20.759 1.00 81.18 C ANISOU 145 CG2 ILE A 497 11116 5384 14343 -1085 1253 845 C ATOM 146 CD1 ILE A 497 -10.544 -1.836 23.541 1.00 93.33 C ANISOU 146 CD1 ILE A 497 12963 6620 15877 -1390 705 -137 C ATOM 147 N VAL A 498 -11.344 -5.532 19.173 1.00 63.35 N ANISOU 147 N VAL A 498 8565 4178 11327 -621 1108 1354 N ATOM 148 CA VAL A 498 -10.872 -5.855 17.827 1.00 64.52 C ANISOU 148 CA VAL A 498 8610 4541 11365 -586 1386 1710 C ATOM 149 C VAL A 498 -11.994 -6.200 16.842 1.00 65.97 C ANISOU 149 C VAL A 498 8947 5149 10971 -215 1436 2054 C ATOM 150 O VAL A 498 -12.141 -5.527 15.828 1.00 68.05 O ANISOU 150 O VAL A 498 9326 5357 11171 -46 1763 2504 O ATOM 151 CB VAL A 498 -9.864 -7.033 17.853 1.00 72.47 C ANISOU 151 CB VAL A 498 9319 5840 12378 -783 1261 1491 C ATOM 152 CG1 VAL A 498 -9.635 -7.581 16.444 1.00 72.78 C ANISOU 152 CG1 VAL A 498 9335 6188 12130 -660 1556 1813 C ATOM 153 CG2 VAL A 498 -8.547 -6.588 18.467 1.00 60.70 C ANISOU 153 CG2 VAL A 498 7564 4007 11493 -1165 1270 1287 C ATOM 154 N CYS A 499 -12.773 -7.244 17.120 1.00 56.76 N ANISOU 154 N CYS A 499 7766 4422 9379 -100 1113 1859 N ATOM 155 CA CYS A 499 -13.757 -7.713 16.143 1.00 56.79 C ANISOU 155 CA CYS A 499 7845 4915 8818 163 1093 2114 C ATOM 156 C CYS A 499 -15.205 -7.363 16.490 1.00 60.37 C ANISOU 156 C CYS A 499 8388 5485 9063 442 927 2221 C ATOM 157 O CYS A 499 -16.110 -7.639 15.699 1.00 61.20 O ANISOU 157 O CYS A 499 8499 6044 8712 656 861 2458 O ATOM 158 CB CYS A 499 -13.640 -9.231 15.964 1.00 48.29 C ANISOU 158 CB CYS A 499 6666 4275 7408 63 907 1843 C ATOM 159 SG CYS A 499 -13.991 -10.157 17.463 1.00 47.92 S ANISOU 159 SG CYS A 499 6531 4266 7410 -34 515 1363 S ATOM 160 N LYS A 500 -15.411 -6.761 17.662 1.00 61.06 N ANISOU 160 N LYS A 500 8533 5196 9472 441 862 2039 N ATOM 161 CA LYS A 500 -16.732 -6.326 18.143 1.00 54.58 C ANISOU 161 CA LYS A 500 7789 4405 8543 741 783 2142 C ATOM 162 C LYS A 500 -17.660 -7.492 18.508 1.00 58.11 C ANISOU 162 C LYS A 500 8103 5359 8618 788 452 1946 C ATOM 163 O LYS A 500 -18.878 -7.324 18.553 1.00 58.18 O ANISOU 163 O LYS A 500 8077 5581 8448 1063 392 2132 O ATOM 164 CB LYS A 500 -17.434 -5.434 17.110 1.00 61.80 C ANISOU 164 CB LYS A 500 8779 5379 9323 1099 1021 2723 C ATOM 165 CG LYS A 500 -16.558 -4.354 16.475 1.00 76.14 C ANISOU 165 CG LYS A 500 10735 6720 11476 1074 1435 3038 C ATOM 166 CD LYS A 500 -16.950 -4.132 15.014 1.00 84.98 C ANISOU 166 CD LYS A 500 11869 8206 12212 1374 1611 3638 C ATOM 167 CE LYS A 500 -15.838 -3.445 14.231 1.00 95.34 C ANISOU 167 CE LYS A 500 13247 9234 13742 1236 1991 3822 C ATOM 168 NZ LYS A 500 -15.809 -3.891 12.810 1.00 97.83 N ANISOU 168 NZ LYS A 500 13559 10074 13538 1379 2082 4221 N ATOM 169 N ARG A 501 -17.105 -8.670 18.776 1.00 49.92 N ANISOU 169 N ARG A 501 6966 4499 7503 532 271 1601 N ATOM 170 CA ARG A 501 -17.955 -9.772 19.204 1.00 50.57 C ANISOU 170 CA ARG A 501 6941 4960 7313 538 17 1411 C ATOM 171 C ARG A 501 -18.447 -9.504 20.617 1.00 56.61 C ANISOU 171 C ARG A 501 7760 5506 8244 625 -61 1223 C ATOM 172 O ARG A 501 -17.758 -8.868 21.415 1.00 58.66 O ANISOU 172 O ARG A 501 8143 5345 8801 552 -4 1051 O ATOM 173 CB ARG A 501 -17.224 -11.117 19.123 1.00 40.45 C ANISOU 173 CB ARG A 501 5582 3846 5940 280 -82 1123 C ATOM 174 CG ARG A 501 -17.345 -11.764 17.744 1.00 46.35 C ANISOU 174 CG ARG A 501 6298 4993 6320 243 -54 1240 C ATOM 175 CD ARG A 501 -16.500 -13.017 17.626 1.00 54.65 C ANISOU 175 CD ARG A 501 7329 6094 7342 18 -45 953 C ATOM 176 NE ARG A 501 -16.257 -13.363 16.231 1.00 57.24 N ANISOU 176 NE ARG A 501 7714 6683 7353 -21 90 1045 N ATOM 177 CZ ARG A 501 -16.858 -14.363 15.597 1.00 61.56 C ANISOU 177 CZ ARG A 501 8278 7605 7507 -105 -8 902 C ATOM 178 NH1 ARG A 501 -17.736 -15.125 16.238 1.00 58.79 N ANISOU 178 NH1 ARG A 501 7848 7382 7106 -179 -222 694 N ATOM 179 NH2 ARG A 501 -16.575 -14.603 14.323 1.00 67.57 N ANISOU 179 NH2 ARG A 501 9148 8605 7920 -135 131 952 N ATOM 180 N SER A 502 -19.649 -9.987 20.910 1.00 49.40 N ANISOU 180 N SER A 502 6748 4900 7124 765 -182 1246 N ATOM 181 CA SER A 502 -20.317 -9.698 22.169 1.00 42.10 C ANISOU 181 CA SER A 502 5884 3819 6292 925 -185 1137 C ATOM 182 C SER A 502 -20.297 -10.911 23.095 1.00 43.63 C ANISOU 182 C SER A 502 6029 4143 6405 774 -346 824 C ATOM 183 O SER A 502 -20.549 -12.028 22.665 1.00 39.75 O ANISOU 183 O SER A 502 5383 3984 5736 646 -451 795 O ATOM 184 CB SER A 502 -21.753 -9.251 21.895 1.00 43.98 C ANISOU 184 CB SER A 502 5999 4296 6414 1254 -130 1475 C ATOM 185 OG SER A 502 -22.612 -9.554 22.976 1.00 53.49 O ANISOU 185 OG SER A 502 7159 5560 7606 1378 -149 1366 O ATOM 186 N TYR A 503 -19.990 -10.685 24.368 1.00 46.06 N ANISOU 186 N TYR A 503 6497 4177 6829 790 -348 587 N ATOM 187 CA TYR A 503 -19.912 -11.767 25.342 1.00 39.37 C ANISOU 187 CA TYR A 503 5639 3437 5884 706 -470 353 C ATOM 188 C TYR A 503 -20.655 -11.411 26.618 1.00 46.24 C ANISOU 188 C TYR A 503 6651 4212 6707 929 -402 279 C ATOM 189 O TYR A 503 -20.577 -10.277 27.094 1.00 52.62 O ANISOU 189 O TYR A 503 7670 4708 7617 1051 -302 213 O ATOM 190 CB TYR A 503 -18.451 -12.089 25.657 1.00 34.20 C ANISOU 190 CB TYR A 503 5029 2629 5335 482 -583 117 C ATOM 191 CG TYR A 503 -17.729 -12.567 24.438 1.00 44.99 C ANISOU 191 CG TYR A 503 6257 4096 6741 299 -576 194 C ATOM 192 CD1 TYR A 503 -17.019 -11.676 23.630 1.00 36.68 C ANISOU 192 CD1 TYR A 503 5217 2859 5860 227 -478 293 C ATOM 193 CD2 TYR A 503 -17.784 -13.919 24.065 1.00 35.66 C ANISOU 193 CD2 TYR A 503 4958 3162 5429 203 -609 172 C ATOM 194 CE1 TYR A 503 -16.370 -12.123 22.481 1.00 42.99 C ANISOU 194 CE1 TYR A 503 5911 3772 6652 93 -412 384 C ATOM 195 CE2 TYR A 503 -17.151 -14.369 22.929 1.00 36.66 C ANISOU 195 CE2 TYR A 503 5011 3369 5551 60 -550 208 C ATOM 196 CZ TYR A 503 -16.443 -13.476 22.142 1.00 45.74 C ANISOU 196 CZ TYR A 503 6171 4386 6822 21 -452 321 C ATOM 197 OH TYR A 503 -15.822 -13.946 21.012 1.00 49.53 O ANISOU 197 OH TYR A 503 6601 4965 7253 -89 -339 369 O ATOM 198 N VAL A 504 -21.369 -12.391 27.157 1.00 45.11 N ANISOU 198 N VAL A 504 6414 4309 6418 973 -413 282 N ATOM 199 CA VAL A 504 -22.113 -12.263 28.403 1.00 52.52 C ANISOU 199 CA VAL A 504 7480 5215 7260 1204 -297 238 C ATOM 200 C VAL A 504 -21.191 -12.450 29.616 1.00 52.02 C ANISOU 200 C VAL A 504 7662 5007 7098 1155 -400 -56 C ATOM 201 O VAL A 504 -21.452 -11.952 30.705 1.00 51.20 O ANISOU 201 O VAL A 504 7796 4785 6872 1343 -313 -182 O ATOM 202 CB VAL A 504 -23.276 -13.292 28.423 1.00 49.88 C ANISOU 202 CB VAL A 504 6897 5212 6843 1244 -227 412 C ATOM 203 CG1 VAL A 504 -23.705 -13.659 29.835 1.00 46.01 C ANISOU 203 CG1 VAL A 504 6544 4717 6220 1413 -96 349 C ATOM 204 CG2 VAL A 504 -24.439 -12.756 27.626 1.00 48.82 C ANISOU 204 CG2 VAL A 504 6521 5261 6767 1401 -130 704 C ATOM 205 N CYS A 505 -20.092 -13.159 29.408 1.00 50.09 N ANISOU 205 N CYS A 505 7354 4798 6881 924 -583 -158 N ATOM 206 CA CYS A 505 -19.126 -13.425 30.470 1.00 50.19 C ANISOU 206 CA CYS A 505 7513 4774 6784 883 -749 -385 C ATOM 207 C CYS A 505 -17.767 -12.859 30.077 1.00 53.43 C ANISOU 207 C CYS A 505 7901 5018 7381 657 -924 -545 C ATOM 208 O CYS A 505 -17.249 -13.158 28.996 1.00 52.74 O ANISOU 208 O CYS A 505 7616 4955 7469 493 -933 -442 O ATOM 209 CB CYS A 505 -19.008 -14.944 30.746 1.00 47.95 C ANISOU 209 CB CYS A 505 7114 4706 6399 864 -781 -300 C ATOM 210 SG CYS A 505 -20.591 -15.809 30.972 1.00 59.21 S ANISOU 210 SG CYS A 505 8465 6310 7723 1019 -524 -69 S ATOM 211 N LEU A 506 -17.187 -12.051 30.955 1.00 52.26 N ANISOU 211 N LEU A 506 7952 4710 7194 629 -1049 -814 N ATOM 212 CA LEU A 506 -15.881 -11.474 30.698 1.00 47.57 C ANISOU 212 CA LEU A 506 7286 3958 6830 359 -1224 -991 C ATOM 213 C LEU A 506 -14.855 -12.586 30.447 1.00 51.18 C ANISOU 213 C LEU A 506 7456 4644 7345 230 -1399 -920 C ATOM 214 O LEU A 506 -13.993 -12.463 29.572 1.00 53.60 O ANISOU 214 O LEU A 506 7554 4882 7931 29 -1410 -877 O ATOM 215 CB LEU A 506 -15.450 -10.587 31.867 1.00 49.25 C ANISOU 215 CB LEU A 506 7758 4016 6939 299 -1388 -1371 C ATOM 216 CG LEU A 506 -14.331 -9.569 31.630 1.00 61.02 C ANISOU 216 CG LEU A 506 9210 5223 8753 -39 -1511 -1614 C ATOM 217 CD1 LEU A 506 -14.694 -8.585 30.528 1.00 66.23 C ANISOU 217 CD1 LEU A 506 9908 5503 9752 -73 -1197 -1455 C ATOM 218 CD2 LEU A 506 -14.007 -8.827 32.916 1.00 58.22 C ANISOU 218 CD2 LEU A 506 9145 4761 8215 -134 -1715 -2077 C ATOM 219 N THR A 507 -14.960 -13.684 31.190 1.00 44.44 N ANISOU 219 N THR A 507 6594 4043 6246 381 -1477 -866 N ATOM 220 CA THR A 507 -13.975 -14.752 31.037 1.00 44.37 C ANISOU 220 CA THR A 507 6330 4216 6315 330 -1597 -766 C ATOM 221 C THR A 507 -14.024 -15.319 29.622 1.00 39.99 C ANISOU 221 C THR A 507 5589 3624 5981 253 -1381 -560 C ATOM 222 O THR A 507 -13.001 -15.664 29.052 1.00 48.20 O ANISOU 222 O THR A 507 6405 4681 7228 140 -1406 -516 O ATOM 223 CB THR A 507 -14.169 -15.881 32.067 1.00 47.95 C ANISOU 223 CB THR A 507 6843 4904 6474 566 -1644 -664 C ATOM 224 OG1 THR A 507 -15.446 -16.500 31.882 1.00 40.77 O ANISOU 224 OG1 THR A 507 6030 3990 5472 707 -1362 -483 O ATOM 225 CG2 THR A 507 -14.052 -15.336 33.488 1.00 41.86 C ANISOU 225 CG2 THR A 507 6290 4242 5372 661 -1881 -883 C ATOM 226 N SER A 508 -15.210 -15.375 29.040 1.00 44.31 N ANISOU 226 N SER A 508 6219 4146 6471 312 -1167 -443 N ATOM 227 CA SER A 508 -15.338 -15.754 27.637 1.00 42.34 C ANISOU 227 CA SER A 508 5839 3900 6346 210 -996 -305 C ATOM 228 C SER A 508 -14.639 -14.787 26.673 1.00 43.60 C ANISOU 228 C SER A 508 5922 3919 6725 50 -967 -304 C ATOM 229 O SER A 508 -14.019 -15.222 25.703 1.00 51.11 O ANISOU 229 O SER A 508 6734 4893 7791 -49 -869 -229 O ATOM 230 CB SER A 508 -16.808 -15.860 27.261 1.00 38.77 C ANISOU 230 CB SER A 508 5445 3526 5761 283 -846 -194 C ATOM 231 OG SER A 508 -17.404 -16.976 27.893 1.00 39.98 O ANISOU 231 OG SER A 508 5615 3789 5788 370 -792 -152 O ATOM 232 N LEU A 509 -14.741 -13.482 26.928 1.00 41.05 N ANISOU 232 N LEU A 509 5715 3414 6469 36 -994 -377 N ATOM 233 CA LEU A 509 -14.096 -12.502 26.057 1.00 42.92 C ANISOU 233 CA LEU A 509 5897 3449 6962 -119 -905 -334 C ATOM 234 C LEU A 509 -12.596 -12.647 26.152 1.00 45.48 C ANISOU 234 C LEU A 509 6006 3751 7522 -312 -1020 -430 C ATOM 235 O LEU A 509 -11.879 -12.510 25.161 1.00 50.46 O ANISOU 235 O LEU A 509 6481 4324 8369 -441 -878 -314 O ATOM 236 CB LEU A 509 -14.492 -11.065 26.418 1.00 41.18 C ANISOU 236 CB LEU A 509 5883 2937 6826 -96 -858 -408 C ATOM 237 CG LEU A 509 -13.748 -9.984 25.616 1.00 40.23 C ANISOU 237 CG LEU A 509 5726 2518 7042 -278 -715 -344 C ATOM 238 CD1 LEU A 509 -14.704 -8.870 25.210 1.00 56.40 C ANISOU 238 CD1 LEU A 509 7985 4324 9121 -115 -480 -173 C ATOM 239 CD2 LEU A 509 -12.580 -9.418 26.400 1.00 43.33 C ANISOU 239 CD2 LEU A 509 6070 2706 7689 -540 -889 -639 C ATOM 240 N ARG A 510 -12.129 -12.892 27.367 1.00 45.89 N ANISOU 240 N ARG A 510 6034 3885 7518 -314 -1274 -621 N ATOM 241 CA ARG A 510 -10.717 -13.121 27.592 1.00 54.11 C ANISOU 241 CA ARG A 510 6784 5003 8773 -469 -1449 -689 C ATOM 242 C ARG A 510 -10.288 -14.370 26.823 1.00 51.89 C ANISOU 242 C ARG A 510 6288 4887 8539 -391 -1299 -478 C ATOM 243 O ARG A 510 -9.287 -14.341 26.105 1.00 52.47 O ANISOU 243 O ARG A 510 6103 4934 8900 -520 -1201 -396 O ATOM 244 CB ARG A 510 -10.417 -13.253 29.089 1.00 54.32 C ANISOU 244 CB ARG A 510 6830 5195 8614 -430 -1801 -904 C ATOM 245 CG ARG A 510 -10.702 -11.988 29.897 1.00 62.90 C ANISOU 245 CG ARG A 510 8176 6086 9637 -541 -1937 -1208 C ATOM 246 CD ARG A 510 -9.555 -11.001 29.840 1.00 65.50 C ANISOU 246 CD ARG A 510 8310 6240 10336 -907 -2079 -1413 C ATOM 247 NE ARG A 510 -10.007 -9.607 29.709 1.00 74.14 N ANISOU 247 NE ARG A 510 9691 6899 11579 -1053 -1916 -1583 N ATOM 248 CZ ARG A 510 -10.410 -8.841 30.720 1.00 79.52 C ANISOU 248 CZ ARG A 510 10707 7426 12082 -1076 -2035 -1925 C ATOM 249 NH1 ARG A 510 -10.444 -9.321 31.954 1.00 79.08 N ANISOU 249 NH1 ARG A 510 10750 7676 11620 -964 -2346 -2132 N ATOM 250 NH2 ARG A 510 -10.791 -7.590 30.496 1.00 93.26 N ANISOU 250 NH2 ARG A 510 12718 8688 14027 -1181 -1801 -2046 N ATOM 251 N ARG A 511 -11.054 -15.453 26.965 1.00 46.26 N ANISOU 251 N ARG A 511 5695 4309 7574 -187 -1232 -394 N ATOM 252 CA ARG A 511 -10.756 -16.704 26.263 1.00 39.34 C ANISOU 252 CA ARG A 511 4699 3512 6737 -110 -1033 -244 C ATOM 253 C ARG A 511 -10.646 -16.448 24.768 1.00 40.08 C ANISOU 253 C ARG A 511 4763 3514 6950 -227 -758 -155 C ATOM 254 O ARG A 511 -9.716 -16.909 24.109 1.00 46.79 O ANISOU 254 O ARG A 511 5423 4371 7985 -246 -594 -74 O ATOM 255 CB ARG A 511 -11.833 -17.769 26.532 1.00 36.41 C ANISOU 255 CB ARG A 511 4520 3205 6110 56 -941 -199 C ATOM 256 CG ARG A 511 -11.678 -19.040 25.679 1.00 33.15 C ANISOU 256 CG ARG A 511 4072 2777 5747 92 -667 -109 C ATOM 257 CD ARG A 511 -12.592 -20.159 26.156 1.00 34.27 C ANISOU 257 CD ARG A 511 4377 2922 5722 210 -574 -81 C ATOM 258 NE ARG A 511 -13.997 -19.753 26.118 1.00 36.51 N ANISOU 258 NE ARG A 511 4826 3238 5810 150 -583 -127 N ATOM 259 CZ ARG A 511 -14.994 -20.460 26.633 1.00 33.73 C ANISOU 259 CZ ARG A 511 4584 2897 5333 208 -513 -99 C ATOM 260 NH1 ARG A 511 -14.756 -21.629 27.229 1.00 32.70 N ANISOU 260 NH1 ARG A 511 4477 2704 5244 333 -402 -17 N ATOM 261 NH2 ARG A 511 -16.232 -19.999 26.551 1.00 35.31 N ANISOU 261 NH2 ARG A 511 4849 3168 5400 160 -520 -111 N ATOM 262 N HIS A 512 -11.602 -15.686 24.254 1.00 36.95 N ANISOU 262 N HIS A 512 4554 3055 6428 -264 -689 -140 N ATOM 263 CA HIS A 512 -11.687 -15.379 22.837 1.00 41.69 C ANISOU 263 CA HIS A 512 5181 3632 7026 -330 -442 -13 C ATOM 264 C HIS A 512 -10.563 -14.469 22.347 1.00 50.67 C ANISOU 264 C HIS A 512 6151 4620 8481 -473 -341 60 C ATOM 265 O HIS A 512 -10.012 -14.676 21.265 1.00 54.72 O ANISOU 265 O HIS A 512 6587 5150 9052 -505 -84 184 O ATOM 266 CB HIS A 512 -13.030 -14.715 22.530 1.00 39.58 C ANISOU 266 CB HIS A 512 5114 3385 6538 -276 -433 51 C ATOM 267 CG HIS A 512 -12.965 -13.755 21.388 1.00 49.40 C ANISOU 267 CG HIS A 512 6387 4561 7822 -317 -247 234 C ATOM 268 ND1 HIS A 512 -12.960 -14.167 20.073 1.00 45.11 N ANISOU 268 ND1 HIS A 512 5861 4168 7110 -324 -43 358 N ATOM 269 CD2 HIS A 512 -12.879 -12.406 21.360 1.00 56.73 C ANISOU 269 CD2 HIS A 512 7360 5264 8931 -341 -198 329 C ATOM 270 CE1 HIS A 512 -12.879 -13.113 19.283 1.00 38.87 C ANISOU 270 CE1 HIS A 512 5112 3295 6362 -319 116 573 C ATOM 271 NE2 HIS A 512 -12.836 -12.031 20.039 1.00 62.65 N ANISOU 271 NE2 HIS A 512 8136 6044 9623 -331 45 573 N ATOM 272 N PHE A 513 -10.237 -13.452 23.140 1.00 46.00 N ANISOU 272 N PHE A 513 5517 3865 8094 -578 -512 -33 N ATOM 273 CA PHE A 513 -9.323 -12.399 22.694 1.00 48.97 C ANISOU 273 CA PHE A 513 5745 4027 8834 -779 -391 29 C ATOM 274 C PHE A 513 -7.908 -12.934 22.420 1.00 54.15 C ANISOU 274 C PHE A 513 6030 4757 9787 -876 -310 82 C ATOM 275 O PHE A 513 -7.116 -12.277 21.742 1.00 58.61 O ANISOU 275 O PHE A 513 6422 5177 10670 -1038 -94 208 O ATOM 276 CB PHE A 513 -9.281 -11.271 23.734 1.00 43.60 C ANISOU 276 CB PHE A 513 5123 3118 8325 -926 -610 -177 C ATOM 277 CG PHE A 513 -8.590 -10.004 23.263 1.00 51.33 C ANISOU 277 CG PHE A 513 6021 3760 9721 -1178 -432 -123 C ATOM 278 CD1 PHE A 513 -9.240 -9.109 22.429 1.00 52.60 C ANISOU 278 CD1 PHE A 513 6416 3680 9888 -1121 -135 91 C ATOM 279 CD2 PHE A 513 -7.309 -9.698 23.688 1.00 53.52 C ANISOU 279 CD2 PHE A 513 5965 3965 10403 -1472 -559 -263 C ATOM 280 CE1 PHE A 513 -8.622 -7.941 22.009 1.00 57.02 C ANISOU 280 CE1 PHE A 513 6934 3860 10873 -1346 98 183 C ATOM 281 CE2 PHE A 513 -6.677 -8.521 23.278 1.00 61.50 C ANISOU 281 CE2 PHE A 513 6887 4612 11870 -1764 -359 -223 C ATOM 282 CZ PHE A 513 -7.335 -7.642 22.436 1.00 62.11 C ANISOU 282 CZ PHE A 513 7254 4380 11963 -1695 2 7 C ATOM 283 N ASN A 514 -7.587 -14.125 22.922 1.00 55.21 N ANISOU 283 N ASN A 514 6024 5104 9847 -749 -430 33 N ATOM 284 CA ASN A 514 -6.244 -14.657 22.701 1.00 56.32 C ANISOU 284 CA ASN A 514 5766 5331 10300 -772 -328 129 C ATOM 285 C ASN A 514 -6.019 -14.931 21.225 1.00 48.82 C ANISOU 285 C ASN A 514 4833 4352 9365 -727 140 331 C ATOM 286 O ASN A 514 -4.893 -14.920 20.744 1.00 51.48 O ANISOU 286 O ASN A 514 4842 4683 10036 -786 357 465 O ATOM 287 CB ASN A 514 -5.992 -15.924 23.514 1.00 56.01 C ANISOU 287 CB ASN A 514 5600 5505 10176 -561 -497 106 C ATOM 288 CG ASN A 514 -4.523 -16.287 23.554 1.00 63.68 C ANISOU 288 CG ASN A 514 6064 6597 11537 -557 -468 228 C ATOM 289 OD1 ASN A 514 -3.688 -15.508 24.032 1.00 67.28 O ANISOU 289 OD1 ASN A 514 6172 7084 12306 -776 -695 179 O ATOM 290 ND2 ASN A 514 -4.191 -17.465 23.043 1.00 64.46 N ANISOU 290 ND2 ASN A 514 6095 6753 11643 -317 -173 380 N ATOM 291 N ILE A 515 -7.117 -15.154 20.515 1.00 46.00 N ANISOU 291 N ILE A 515 4848 4010 8622 -623 291 352 N ATOM 292 CA ILE A 515 -7.109 -15.319 19.071 1.00 47.11 C ANISOU 292 CA ILE A 515 5109 4170 8620 -580 703 506 C ATOM 293 C ILE A 515 -6.476 -14.123 18.350 1.00 60.08 C ANISOU 293 C ILE A 515 6634 5659 10534 -728 948 712 C ATOM 294 O ILE A 515 -5.775 -14.297 17.348 1.00 67.90 O ANISOU 294 O ILE A 515 7538 6668 11594 -701 1343 882 O ATOM 295 CB ILE A 515 -8.541 -15.541 18.571 1.00 42.46 C ANISOU 295 CB ILE A 515 4915 3690 7530 -496 690 464 C ATOM 296 CG1 ILE A 515 -8.963 -16.982 18.870 1.00 44.54 C ANISOU 296 CG1 ILE A 515 5281 4064 7578 -385 641 292 C ATOM 297 CG2 ILE A 515 -8.667 -15.224 17.091 1.00 45.14 C ANISOU 297 CG2 ILE A 515 5421 4093 7638 -481 1032 645 C ATOM 298 CD1 ILE A 515 -10.428 -17.237 18.660 1.00 47.10 C ANISOU 298 CD1 ILE A 515 5899 4518 7478 -372 531 201 C ATOM 299 N HIS A 516 -6.701 -12.916 18.871 1.00 61.14 N ANISOU 299 N HIS A 516 6784 5606 10840 -878 768 702 N ATOM 300 CA HIS A 516 -6.105 -11.701 18.294 1.00 61.40 C ANISOU 300 CA HIS A 516 6715 5394 11219 -1054 1033 908 C ATOM 301 C HIS A 516 -4.665 -11.483 18.765 1.00 65.82 C ANISOU 301 C HIS A 516 6781 5860 12366 -1291 1019 881 C ATOM 302 O HIS A 516 -3.784 -11.140 17.970 1.00 70.21 O ANISOU 302 O HIS A 516 7114 6325 13238 -1391 1400 1110 O ATOM 303 CB HIS A 516 -6.944 -10.466 18.640 1.00 51.38 C ANISOU 303 CB HIS A 516 5696 3874 9950 -1117 911 902 C ATOM 304 CG HIS A 516 -8.390 -10.585 18.263 1.00 59.19 C ANISOU 304 CG HIS A 516 7072 5006 10412 -873 880 968 C ATOM 305 ND1 HIS A 516 -8.804 -10.959 17.003 1.00 59.45 N ANISOU 305 ND1 HIS A 516 7274 5256 10059 -703 1142 1193 N ATOM 306 CD2 HIS A 516 -9.521 -10.378 18.983 1.00 53.15 C ANISOU 306 CD2 HIS A 516 6523 4237 9434 -773 612 841 C ATOM 307 CE1 HIS A 516 -10.126 -10.973 16.961 1.00 52.87 C ANISOU 307 CE1 HIS A 516 6694 4578 8818 -535 987 1204 C ATOM 308 NE2 HIS A 516 -10.585 -10.621 18.148 1.00 47.30 N ANISOU 308 NE2 HIS A 516 6007 3726 8238 -560 695 1015 N ATOM 309 N SER A 517 -4.421 -11.687 20.057 1.00 64.83 N ANISOU 309 N SER A 517 6460 5800 12374 -1378 580 619 N ATOM 310 CA SER A 517 -3.125 -11.341 20.648 1.00 68.55 C ANISOU 310 CA SER A 517 6410 6243 13395 -1656 441 554 C ATOM 311 C SER A 517 -2.082 -12.458 20.549 1.00 74.45 C ANISOU 311 C SER A 517 6707 7271 14309 -1524 526 666 C ATOM 312 O SER A 517 -0.893 -12.187 20.426 1.00 78.80 O ANISOU 312 O SER A 517 6749 7823 15367 -1717 641 776 O ATOM 313 CB SER A 517 -3.308 -10.957 22.120 1.00 65.41 C ANISOU 313 CB SER A 517 6007 5841 13004 -1815 -114 206 C ATOM 314 OG SER A 517 -3.781 -12.067 22.877 1.00 65.65 O ANISOU 314 OG SER A 517 6139 6169 12636 -1540 -413 89 O ATOM 315 N TRP A 518 -2.535 -13.707 20.616 1.00 74.17 N ANISOU 315 N TRP A 518 7929 5572 14680 -1224 995 -314 N ATOM 316 CA TRP A 518 -1.640 -14.860 20.726 1.00 70.91 C ANISOU 316 CA TRP A 518 7493 5581 13868 -1301 834 -341 C ATOM 317 C TRP A 518 -0.704 -14.696 21.910 1.00 70.21 C ANISOU 317 C TRP A 518 7229 5585 13862 -1589 733 -827 C ATOM 318 O TRP A 518 0.438 -15.151 21.869 1.00 64.25 O ANISOU 318 O TRP A 518 6337 5042 13033 -1709 664 -778 O ATOM 319 CB TRP A 518 -0.825 -15.070 19.442 1.00 67.14 C ANISOU 319 CB TRP A 518 6983 5134 13394 -1283 950 127 C ATOM 320 CG TRP A 518 -1.582 -15.784 18.383 1.00 66.58 C ANISOU 320 CG TRP A 518 7095 5252 12949 -1062 966 551 C ATOM 321 CD1 TRP A 518 -2.252 -15.224 17.336 1.00 68.67 C ANISOU 321 CD1 TRP A 518 7430 5326 13337 -968 1096 992 C ATOM 322 CD2 TRP A 518 -1.772 -17.197 18.273 1.00 63.50 C ANISOU 322 CD2 TRP A 518 6824 5300 12004 -941 845 582 C ATOM 323 NE1 TRP A 518 -2.846 -16.203 16.577 1.00 67.95 N ANISOU 323 NE1 TRP A 518 7506 5579 12732 -829 1048 1266 N ATOM 324 CE2 TRP A 518 -2.566 -17.425 17.132 1.00 62.58 C ANISOU 324 CE2 TRP A 518 6867 5256 11654 -806 917 988 C ATOM 325 CE3 TRP A 518 -1.344 -18.295 19.028 1.00 71.92 C ANISOU 325 CE3 TRP A 518 7850 6701 12774 -950 684 331 C ATOM 326 CZ2 TRP A 518 -2.937 -18.707 16.720 1.00 61.64 C ANISOU 326 CZ2 TRP A 518 6892 5515 11014 -700 863 1070 C ATOM 327 CZ3 TRP A 518 -1.719 -19.576 18.618 1.00 72.49 C ANISOU 327 CZ3 TRP A 518 8049 7094 12400 -803 643 457 C ATOM 328 CH2 TRP A 518 -2.507 -19.767 17.475 1.00 64.65 C ANISOU 328 CH2 TRP A 518 7238 6146 11182 -690 747 783 C ATOM 329 N GLU A 519 -1.189 -14.032 22.956 1.00 69.67 N ANISOU 329 N GLU A 519 7162 5424 13884 -1691 732 -1278 N ATOM 330 CA GLU A 519 -0.423 -13.872 24.185 1.00 67.10 C ANISOU 330 CA GLU A 519 6712 5340 13442 -1979 606 -1752 C ATOM 331 C GLU A 519 -0.061 -15.231 24.772 1.00 68.14 C ANISOU 331 C GLU A 519 6773 5984 13134 -2074 310 -1811 C ATOM 332 O GLU A 519 1.100 -15.486 25.105 1.00 70.41 O ANISOU 332 O GLU A 519 6876 6530 13346 -2266 173 -1833 O ATOM 333 CB GLU A 519 -1.203 -13.039 25.204 1.00 76.93 C ANISOU 333 CB GLU A 519 8020 6496 14716 -2047 691 -2223 C ATOM 334 CG GLU A 519 -0.856 -13.354 26.648 1.00 87.09 C ANISOU 334 CG GLU A 519 9258 8240 15591 -2335 486 -2699 C ATOM 335 CD GLU A 519 -0.983 -12.152 27.554 1.00101.83 C ANISOU 335 CD GLU A 519 11119 9978 17594 -2522 657 -3175 C ATOM 336 OE1 GLU A 519 -0.851 -11.016 27.052 1.00107.55 O ANISOU 336 OE1 GLU A 519 11793 10252 18818 -2485 914 -3138 O ATOM 337 OE2 GLU A 519 -1.222 -12.341 28.767 1.00107.98 O ANISOU 337 OE2 GLU A 519 11930 11119 17978 -2709 550 -3569 O ATOM 338 N LYS A 520 -1.056 -16.103 24.892 1.00 62.27 N ANISOU 338 N LYS A 520 6197 5479 11985 -1852 203 -1741 N ATOM 339 CA LYS A 520 -0.804 -17.487 25.264 1.00 62.47 C ANISOU 339 CA LYS A 520 6191 6032 11510 -1802 -59 -1626 C ATOM 340 C LYS A 520 -0.790 -18.368 24.033 1.00 62.37 C ANISOU 340 C LYS A 520 6262 6049 11386 -1506 -6 -1120 C ATOM 341 O LYS A 520 -1.589 -18.171 23.111 1.00 56.37 O ANISOU 341 O LYS A 520 5679 5055 10685 -1292 157 -891 O ATOM 342 CB LYS A 520 -1.855 -18.007 26.243 1.00 67.86 C ANISOU 342 CB LYS A 520 6993 7010 11780 -1771 -210 -1875 C ATOM 343 CG LYS A 520 -1.754 -17.417 27.637 1.00 86.76 C ANISOU 343 CG LYS A 520 9287 9558 14118 -2142 -293 -2432 C ATOM 344 CD LYS A 520 -2.707 -18.139 28.586 1.00 95.44 C ANISOU 344 CD LYS A 520 10490 11055 14716 -2122 -454 -2614 C ATOM 345 CE LYS A 520 -2.849 -17.400 29.912 1.00104.11 C ANISOU 345 CE LYS A 520 11609 12323 15627 -2416 -435 -3109 C ATOM 346 NZ LYS A 520 -3.886 -18.021 30.788 1.00101.06 N ANISOU 346 NZ LYS A 520 11351 12297 14751 -2374 -530 -3244 N ATOM 347 N LYS A 521 0.124 -19.337 24.032 1.00 62.42 N ANISOU 347 N LYS A 521 6115 6356 11247 -1521 -133 -947 N ATOM 348 CA LYS A 521 0.177 -20.367 23.006 1.00 54.20 C ANISOU 348 CA LYS A 521 5135 5392 10066 -1279 -56 -561 C ATOM 349 C LYS A 521 -0.170 -21.730 23.591 1.00 56.35 C ANISOU 349 C LYS A 521 5410 6050 9952 -1165 -261 -528 C ATOM 350 O LYS A 521 0.230 -22.050 24.720 1.00 52.48 O ANISOU 350 O LYS A 521 4738 5849 9353 -1324 -499 -670 O ATOM 351 CB LYS A 521 1.565 -20.427 22.367 1.00 54.53 C ANISOU 351 CB LYS A 521 4958 5380 10381 -1360 57 -355 C ATOM 352 CG LYS A 521 1.770 -19.473 21.216 1.00 59.70 C ANISOU 352 CG LYS A 521 5670 5665 11350 -1366 339 -184 C ATOM 353 CD LYS A 521 2.359 -18.184 21.709 1.00 69.30 C ANISOU 353 CD LYS A 521 6731 6641 12960 -1630 354 -408 C ATOM 354 CE LYS A 521 2.649 -17.230 20.572 1.00 69.10 C ANISOU 354 CE LYS A 521 6720 6231 13305 -1647 638 -174 C ATOM 355 NZ LYS A 521 3.335 -16.038 21.112 1.00 77.51 N ANISOU 355 NZ LYS A 521 7597 7040 14813 -1930 663 -419 N ATOM 356 N TYR A 522 -0.904 -22.530 22.816 1.00 49.79 N ANISOU 356 N TYR A 522 4767 5239 8912 -919 -172 -320 N ATOM 357 CA TYR A 522 -1.168 -23.927 23.164 1.00 49.30 C ANISOU 357 CA TYR A 522 4694 5477 8563 -789 -308 -233 C ATOM 358 C TYR A 522 -0.618 -24.842 22.071 1.00 48.59 C ANISOU 358 C TYR A 522 4567 5359 8538 -660 -110 37 C ATOM 359 O TYR A 522 -1.289 -25.098 21.074 1.00 48.72 O ANISOU 359 O TYR A 522 4801 5297 8415 -521 68 146 O ATOM 360 CB TYR A 522 -2.672 -24.166 23.368 1.00 47.27 C ANISOU 360 CB TYR A 522 4690 5286 7986 -642 -368 -310 C ATOM 361 CG TYR A 522 -3.278 -23.233 24.395 1.00 51.91 C ANISOU 361 CG TYR A 522 5316 5864 8542 -773 -482 -629 C ATOM 362 CD1 TYR A 522 -3.351 -23.599 25.729 1.00 54.01 C ANISOU 362 CD1 TYR A 522 5483 6455 8585 -901 -721 -821 C ATOM 363 CD2 TYR A 522 -3.763 -21.981 24.032 1.00 51.45 C ANISOU 363 CD2 TYR A 522 5372 5475 8704 -791 -325 -733 C ATOM 364 CE1 TYR A 522 -3.889 -22.751 26.672 1.00 57.23 C ANISOU 364 CE1 TYR A 522 5927 6876 8940 -1068 -770 -1185 C ATOM 365 CE2 TYR A 522 -4.306 -21.121 24.973 1.00 50.69 C ANISOU 365 CE2 TYR A 522 5291 5315 8656 -922 -356 -1086 C ATOM 366 CZ TYR A 522 -4.369 -21.517 26.290 1.00 52.76 C ANISOU 366 CZ TYR A 522 5477 5924 8644 -1073 -564 -1350 C ATOM 367 OH TYR A 522 -4.902 -20.682 27.242 1.00 51.81 O ANISOU 367 OH TYR A 522 5377 5771 8538 -1249 -547 -1773 O ATOM 368 N PRO A 523 0.625 -25.309 22.236 1.00 46.88 N ANISOU 368 N PRO A 523 4053 5212 8549 -731 -121 138 N ATOM 369 CA PRO A 523 1.228 -26.118 21.169 1.00 50.24 C ANISOU 369 CA PRO A 523 4415 5559 9117 -627 151 340 C ATOM 370 C PRO A 523 0.855 -27.593 21.278 1.00 53.17 C ANISOU 370 C PRO A 523 4773 6075 9353 -458 137 426 C ATOM 371 O PRO A 523 0.889 -28.120 22.394 1.00 49.77 O ANISOU 371 O PRO A 523 4167 5848 8896 -466 -132 447 O ATOM 372 CB PRO A 523 2.735 -25.915 21.383 1.00 48.36 C ANISOU 372 CB PRO A 523 3806 5294 9276 -775 156 416 C ATOM 373 CG PRO A 523 2.875 -25.633 22.857 1.00 49.07 C ANISOU 373 CG PRO A 523 3711 5606 9327 -937 -222 304 C ATOM 374 CD PRO A 523 1.598 -24.914 23.273 1.00 48.70 C ANISOU 374 CD PRO A 523 3975 5565 8966 -952 -336 63 C ATOM 375 N CYS A 524 0.488 -28.229 20.159 1.00 58.20 N ANISOU 375 N CYS A 524 5585 6629 9899 -340 423 474 N ATOM 376 CA CYS A 524 0.217 -29.673 20.153 1.00 55.97 C ANISOU 376 CA CYS A 524 5270 6416 9580 -197 484 526 C ATOM 377 C CYS A 524 1.458 -30.398 20.580 1.00 51.50 C ANISOU 377 C CYS A 524 4284 5837 9445 -192 499 676 C ATOM 378 O CYS A 524 2.540 -30.143 20.056 1.00 50.06 O ANISOU 378 O CYS A 524 3911 5522 9586 -259 708 732 O ATOM 379 CB CYS A 524 -0.210 -30.192 18.777 1.00 56.94 C ANISOU 379 CB CYS A 524 5625 6453 9557 -147 851 491 C ATOM 380 SG CYS A 524 -0.384 -32.029 18.706 1.00 37.34 S ANISOU 380 SG CYS A 524 3056 3966 7166 -3 1022 492 S ATOM 381 N ARG A 525 1.319 -31.316 21.521 1.00 54.96 N ANISOU 381 N ARG A 525 4545 6414 9922 -114 283 784 N ATOM 382 CA ARG A 525 2.505 -32.019 22.002 1.00 67.73 C ANISOU 382 CA ARG A 525 5691 8027 12017 -103 258 1023 C ATOM 383 C ARG A 525 2.798 -33.280 21.184 1.00 61.81 C ANISOU 383 C ARG A 525 4824 7050 11610 51 659 1092 C ATOM 384 O ARG A 525 3.494 -34.177 21.653 1.00 73.29 O ANISOU 384 O ARG A 525 6044 8456 13348 121 618 1297 O ATOM 385 CB ARG A 525 2.340 -32.363 23.478 1.00 76.29 C ANISOU 385 CB ARG A 525 6564 9402 13020 -131 -191 1191 C ATOM 386 CG ARG A 525 1.572 -31.294 24.250 1.00 87.32 C ANISOU 386 CG ARG A 525 8201 11030 13947 -281 -515 991 C ATOM 387 CD ARG A 525 0.636 -31.977 25.223 1.00 93.12 C ANISOU 387 CD ARG A 525 8979 12021 14382 -233 -789 1052 C ATOM 388 NE ARG A 525 -0.474 -31.149 25.687 1.00 81.17 N ANISOU 388 NE ARG A 525 7795 10655 12390 -315 -958 783 N ATOM 389 CZ ARG A 525 -0.462 -30.457 26.819 1.00 84.35 C ANISOU 389 CZ ARG A 525 8125 11343 12583 -533 -1269 685 C ATOM 390 NH1 ARG A 525 0.610 -30.467 27.595 1.00 86.82 N ANISOU 390 NH1 ARG A 525 8075 11871 13042 -709 -1481 853 N ATOM 391 NH2 ARG A 525 -1.527 -29.761 27.179 1.00 91.65 N ANISOU 391 NH2 ARG A 525 9344 12345 13135 -590 -1341 402 N ATOM 392 N TYR A 526 2.281 -33.338 19.957 1.00 52.28 N ANISOU 392 N TYR A 526 3946 5698 10219 74 1029 880 N ATOM 393 CA TYR A 526 2.508 -34.492 19.083 1.00 52.40 C ANISOU 393 CA TYR A 526 3892 5492 10525 163 1489 830 C ATOM 394 C TYR A 526 2.953 -34.062 17.700 1.00 55.49 C ANISOU 394 C TYR A 526 4423 5747 10915 54 1946 653 C ATOM 395 O TYR A 526 3.556 -34.854 16.963 1.00 62.86 O ANISOU 395 O TYR A 526 5321 6474 12088 77 2322 569 O ATOM 396 CB TYR A 526 1.251 -35.348 18.946 1.00 52.49 C ANISOU 396 CB TYR A 526 4178 5530 10235 250 1528 703 C ATOM 397 CG TYR A 526 0.739 -35.893 20.244 1.00 53.22 C ANISOU 397 CG TYR A 526 4142 5765 10312 351 1124 893 C ATOM 398 CD1 TYR A 526 1.149 -37.135 20.714 1.00 52.00 C ANISOU 398 CD1 TYR A 526 3781 5477 10499 447 1131 1077 C ATOM 399 CD2 TYR A 526 -0.149 -35.158 21.011 1.00 47.74 C ANISOU 399 CD2 TYR A 526 3669 5332 9139 310 706 876 C ATOM 400 CE1 TYR A 526 0.675 -37.628 21.910 1.00 48.58 C ANISOU 400 CE1 TYR A 526 3299 5214 9945 492 750 1285 C ATOM 401 CE2 TYR A 526 -0.622 -35.639 22.198 1.00 47.43 C ANISOU 401 CE2 TYR A 526 3518 5475 9029 365 355 1042 C ATOM 402 CZ TYR A 526 -0.219 -36.872 22.643 1.00 44.80 C ANISOU 402 CZ TYR A 526 2918 5054 9051 458 376 1273 C ATOM 403 OH TYR A 526 -0.711 -37.335 23.840 1.00 54.38 O ANISOU 403 OH TYR A 526 4134 6482 10047 460 22 1448 O ATOM 404 N CYS A 527 2.632 -32.821 17.335 1.00 46.79 N ANISOU 404 N CYS A 527 3601 4752 9427 -72 1852 582 N ATOM 405 CA CYS A 527 3.112 -32.280 16.075 1.00 48.52 C ANISOU 405 CA CYS A 527 3927 4893 9616 -210 2245 490 C ATOM 406 C CYS A 527 3.430 -30.787 16.237 1.00 52.96 C ANISOU 406 C CYS A 527 4511 5497 10114 -330 2030 580 C ATOM 407 O CYS A 527 3.649 -30.302 17.350 1.00 56.20 O ANISOU 407 O CYS A 527 4748 5957 10649 -323 1648 679 O ATOM 408 CB CYS A 527 2.098 -32.515 14.952 1.00 45.40 C ANISOU 408 CB CYS A 527 3941 4581 8726 -282 2501 298 C ATOM 409 SG CYS A 527 0.625 -31.485 15.047 1.00 52.10 S ANISOU 409 SG CYS A 527 5211 5647 8938 -318 2114 325 S ATOM 410 N GLU A 528 3.470 -30.062 15.129 1.00 54.42 N ANISOU 410 N GLU A 528 4894 5673 10111 -470 2289 547 N ATOM 411 CA GLU A 528 3.973 -28.693 15.161 1.00 71.29 C ANISOU 411 CA GLU A 528 6988 7768 12330 -592 2178 653 C ATOM 412 C GLU A 528 2.863 -27.675 15.421 1.00 62.82 C ANISOU 412 C GLU A 528 6212 6772 10885 -613 1860 672 C ATOM 413 O GLU A 528 3.133 -26.588 15.895 1.00 68.36 O ANISOU 413 O GLU A 528 6842 7403 11727 -685 1668 724 O ATOM 414 CB GLU A 528 4.712 -28.369 13.851 1.00 84.82 C ANISOU 414 CB GLU A 528 8705 9418 14107 -748 2638 675 C ATOM 415 CG GLU A 528 3.820 -28.330 12.599 1.00 99.83 C ANISOU 415 CG GLU A 528 10991 11463 15476 -855 2878 634 C ATOM 416 CD GLU A 528 3.337 -29.713 12.146 1.00106.62 C ANISOU 416 CD GLU A 528 11960 12405 16147 -817 3133 432 C ATOM 417 OE1 GLU A 528 3.934 -30.732 12.559 1.00105.85 O ANISOU 417 OE1 GLU A 528 11597 12175 16447 -706 3265 336 O ATOM 418 OE2 GLU A 528 2.351 -29.778 11.379 1.00107.03 O ANISOU 418 OE2 GLU A 528 12340 12648 15680 -912 3200 384 O ATOM 419 N LYS A 529 1.618 -28.049 15.141 1.00 56.01 N ANISOU 419 N LYS A 529 5650 6031 9598 -555 1820 619 N ATOM 420 CA LYS A 529 0.492 -27.125 15.224 1.00 53.60 C ANISOU 420 CA LYS A 529 5606 5774 8985 -560 1579 669 C ATOM 421 C LYS A 529 0.369 -26.418 16.577 1.00 53.41 C ANISOU 421 C LYS A 529 5482 5698 9115 -521 1194 629 C ATOM 422 O LYS A 529 0.573 -27.011 17.637 1.00 48.62 O ANISOU 422 O LYS A 529 4699 5150 8624 -455 994 552 O ATOM 423 CB LYS A 529 -0.811 -27.857 14.904 1.00 50.62 C ANISOU 423 CB LYS A 529 5500 5562 8171 -491 1556 618 C ATOM 424 CG LYS A 529 -0.864 -28.411 13.485 1.00 57.89 C ANISOU 424 CG LYS A 529 6572 6597 8826 -612 1938 609 C ATOM 425 CD LYS A 529 -2.232 -29.010 13.165 1.00 69.24 C ANISOU 425 CD LYS A 529 8279 8233 9797 -593 1873 560 C ATOM 426 CE LYS A 529 -2.268 -29.585 11.750 1.00 80.15 C ANISOU 426 CE LYS A 529 9811 9792 10849 -791 2263 496 C ATOM 427 NZ LYS A 529 -1.171 -30.575 11.503 1.00 85.84 N ANISOU 427 NZ LYS A 529 10345 10407 11864 -822 2658 284 N ATOM 428 N VAL A 530 0.049 -25.131 16.523 1.00 50.97 N ANISOU 428 N VAL A 530 5265 5283 8818 -590 1111 689 N ATOM 429 CA VAL A 530 -0.152 -24.351 17.728 1.00 51.99 C ANISOU 429 CA VAL A 530 5327 5345 9082 -602 814 572 C ATOM 430 C VAL A 530 -1.585 -23.805 17.736 1.00 54.57 C ANISOU 430 C VAL A 530 5907 5653 9176 -533 695 578 C ATOM 431 O VAL A 530 -2.120 -23.455 16.687 1.00 59.35 O ANISOU 431 O VAL A 530 6679 6226 9646 -535 836 770 O ATOM 432 CB VAL A 530 0.893 -23.225 17.805 1.00 61.46 C ANISOU 432 CB VAL A 530 6333 6346 10674 -766 861 587 C ATOM 433 CG1 VAL A 530 0.662 -22.335 19.004 1.00 44.68 C ANISOU 433 CG1 VAL A 530 4151 4142 8683 -840 605 388 C ATOM 434 CG2 VAL A 530 2.310 -23.839 17.841 1.00 56.35 C ANISOU 434 CG2 VAL A 530 5385 5734 10293 -825 967 608 C ATOM 435 N PHE A 531 -2.217 -23.757 18.907 1.00 48.76 N ANISOU 435 N PHE A 531 5176 4965 8386 -486 441 393 N ATOM 436 CA PHE A 531 -3.611 -23.317 19.006 1.00 43.92 C ANISOU 436 CA PHE A 531 4763 4319 7606 -399 347 383 C ATOM 437 C PHE A 531 -3.761 -22.155 19.968 1.00 44.03 C ANISOU 437 C PHE A 531 4710 4149 7871 -476 234 181 C ATOM 438 O PHE A 531 -2.998 -22.054 20.926 1.00 45.52 O ANISOU 438 O PHE A 531 4722 4375 8198 -600 127 -32 O ATOM 439 CB PHE A 531 -4.512 -24.487 19.449 1.00 45.36 C ANISOU 439 CB PHE A 531 5050 4744 7439 -264 208 309 C ATOM 440 CG PHE A 531 -4.461 -25.665 18.520 1.00 39.60 C ANISOU 440 CG PHE A 531 4393 4163 6490 -212 359 436 C ATOM 441 CD1 PHE A 531 -3.490 -26.637 18.669 1.00 37.32 C ANISOU 441 CD1 PHE A 531 3936 3950 6294 -221 421 400 C ATOM 442 CD2 PHE A 531 -5.374 -25.781 17.480 1.00 38.21 C ANISOU 442 CD2 PHE A 531 4425 4047 6044 -180 455 591 C ATOM 443 CE1 PHE A 531 -3.439 -27.718 17.806 1.00 44.13 C ANISOU 443 CE1 PHE A 531 4854 4894 7020 -191 632 450 C ATOM 444 CE2 PHE A 531 -5.330 -26.844 16.613 1.00 34.91 C ANISOU 444 CE2 PHE A 531 4083 3781 5401 -194 631 631 C ATOM 445 CZ PHE A 531 -4.361 -27.824 16.773 1.00 37.29 C ANISOU 445 CZ PHE A 531 4231 4104 5833 -196 749 526 C ATOM 446 N PRO A 532 -4.752 -21.272 19.717 1.00 46.09 N ANISOU 446 N PRO A 532 5087 4211 8213 -423 270 247 N ATOM 447 CA PRO A 532 -5.002 -20.083 20.535 1.00 49.22 C ANISOU 447 CA PRO A 532 5419 4347 8934 -498 250 16 C ATOM 448 C PRO A 532 -6.025 -20.290 21.667 1.00 49.79 C ANISOU 448 C PRO A 532 5551 4534 8833 -441 99 -277 C ATOM 449 O PRO A 532 -6.213 -19.389 22.492 1.00 51.64 O ANISOU 449 O PRO A 532 5726 4579 9317 -540 116 -574 O ATOM 450 CB PRO A 532 -5.531 -19.082 19.508 1.00 51.11 C ANISOU 450 CB PRO A 532 5709 4274 9436 -446 415 333 C ATOM 451 CG PRO A 532 -6.302 -19.920 18.572 1.00 44.15 C ANISOU 451 CG PRO A 532 4989 3623 8162 -305 401 647 C ATOM 452 CD PRO A 532 -5.561 -21.246 18.485 1.00 43.31 C ANISOU 452 CD PRO A 532 4893 3845 7720 -325 373 591 C ATOM 453 N LEU A 533 -6.676 -21.449 21.695 1.00 42.07 N ANISOU 453 N LEU A 533 4683 3850 7450 -306 -14 -217 N ATOM 454 CA LEU A 533 -7.523 -21.849 22.819 1.00 43.66 C ANISOU 454 CA LEU A 533 4924 4235 7430 -271 -164 -479 C ATOM 455 C LEU A 533 -7.086 -23.210 23.359 1.00 46.39 C ANISOU 455 C LEU A 533 5225 4959 7442 -279 -331 -509 C ATOM 456 O LEU A 533 -6.754 -24.121 22.593 1.00 38.02 O ANISOU 456 O LEU A 533 4186 4005 6256 -201 -299 -276 O ATOM 457 CB LEU A 533 -8.997 -21.933 22.410 1.00 43.29 C ANISOU 457 CB LEU A 533 5031 4157 7259 -81 -149 -333 C ATOM 458 CG LEU A 533 -9.927 -20.777 22.760 1.00 48.96 C ANISOU 458 CG LEU A 533 5741 4573 8288 -51 -59 -464 C ATOM 459 CD1 LEU A 533 -9.549 -19.587 21.944 1.00 40.06 C ANISOU 459 CD1 LEU A 533 4544 3052 7624 -85 117 -264 C ATOM 460 CD2 LEU A 533 -11.382 -21.160 22.503 1.00 42.54 C ANISOU 460 CD2 LEU A 533 5038 3829 7298 143 -96 -300 C ATOM 461 N ALA A 534 -7.126 -23.366 24.676 1.00 46.41 N ANISOU 461 N ALA A 534 5153 5170 7312 -388 -489 -788 N ATOM 462 CA ALA A 534 -6.776 -24.642 25.281 1.00 39.33 C ANISOU 462 CA ALA A 534 4169 4637 6139 -397 -672 -740 C ATOM 463 C ALA A 534 -7.618 -25.780 24.703 1.00 40.86 C ANISOU 463 C ALA A 534 4504 4933 6087 -177 -669 -522 C ATOM 464 O ALA A 534 -7.087 -26.857 24.393 1.00 42.89 O ANISOU 464 O ALA A 534 4694 5310 6290 -124 -681 -336 O ATOM 465 CB ALA A 534 -6.940 -24.572 26.790 1.00 41.32 C ANISOU 465 CB ALA A 534 4338 5159 6205 -575 -853 -1039 C ATOM 466 N GLN A 535 -8.920 -25.546 24.520 1.00 29.83 N ANISOU 466 N GLN A 535 3279 3464 4591 -57 -629 -544 N ATOM 467 CA GLN A 535 -9.782 -26.654 24.122 1.00 33.62 C ANISOU 467 CA GLN A 535 3879 4086 4808 106 -654 -381 C ATOM 468 C GLN A 535 -9.538 -27.033 22.663 1.00 34.69 C ANISOU 468 C GLN A 535 4090 4124 4964 177 -500 -123 C ATOM 469 O GLN A 535 -9.717 -28.183 22.301 1.00 39.44 O ANISOU 469 O GLN A 535 4736 4860 5390 246 -490 -21 O ATOM 470 CB GLN A 535 -11.265 -26.335 24.374 1.00 30.21 C ANISOU 470 CB GLN A 535 3574 3637 4268 200 -668 -461 C ATOM 471 CG GLN A 535 -11.891 -25.418 23.359 1.00 35.83 C ANISOU 471 CG GLN A 535 4376 4076 5163 279 -530 -316 C ATOM 472 CD GLN A 535 -13.389 -25.312 23.530 1.00 37.18 C ANISOU 472 CD GLN A 535 4624 4244 5258 399 -549 -322 C ATOM 473 OE1 GLN A 535 -13.867 -24.746 24.513 1.00 33.22 O ANISOU 473 OE1 GLN A 535 4080 3698 4845 373 -546 -581 O ATOM 474 NE2 GLN A 535 -14.145 -25.855 22.565 1.00 31.17 N ANISOU 474 NE2 GLN A 535 3964 3547 4333 507 -552 -52 N ATOM 475 N TYR A 536 -9.101 -26.096 21.823 1.00 29.07 N ANISOU 475 N TYR A 536 3385 3191 4468 130 -358 -30 N ATOM 476 CA TYR A 536 -8.840 -26.471 20.434 1.00 28.71 C ANISOU 476 CA TYR A 536 3413 3127 4367 140 -194 201 C ATOM 477 C TYR A 536 -7.672 -27.450 20.386 1.00 35.20 C ANISOU 477 C TYR A 536 4113 4037 5226 99 -130 197 C ATOM 478 O TYR A 536 -7.690 -28.414 19.625 1.00 41.43 O ANISOU 478 O TYR A 536 4960 4907 5872 124 -8 276 O ATOM 479 CB TYR A 536 -8.549 -25.254 19.544 1.00 30.23 C ANISOU 479 CB TYR A 536 3612 3092 4782 75 -53 362 C ATOM 480 CG TYR A 536 -9.694 -24.266 19.379 1.00 32.63 C ANISOU 480 CG TYR A 536 3987 3248 5163 135 -75 470 C ATOM 481 CD1 TYR A 536 -10.958 -24.516 19.905 1.00 35.57 C ANISOU 481 CD1 TYR A 536 4427 3705 5381 246 -197 407 C ATOM 482 CD2 TYR A 536 -9.502 -23.079 18.688 1.00 35.42 C ANISOU 482 CD2 TYR A 536 4304 3354 5801 84 40 673 C ATOM 483 CE1 TYR A 536 -11.993 -23.591 19.758 1.00 34.54 C ANISOU 483 CE1 TYR A 536 4307 3400 5418 318 -194 535 C ATOM 484 CE2 TYR A 536 -10.518 -22.162 18.532 1.00 38.04 C ANISOU 484 CE2 TYR A 536 4639 3499 6314 156 34 835 C ATOM 485 CZ TYR A 536 -11.760 -22.411 19.074 1.00 41.35 C ANISOU 485 CZ TYR A 536 5106 3988 6617 279 -78 761 C ATOM 486 OH TYR A 536 -12.766 -21.469 18.897 1.00 45.59 O ANISOU 486 OH TYR A 536 5594 4299 7427 366 -60 959 O ATOM 487 N ARG A 537 -6.662 -27.216 21.216 1.00 35.66 N ANISOU 487 N ARG A 537 3973 4076 5499 17 -202 96 N ATOM 488 CA ARG A 537 -5.537 -28.125 21.262 1.00 40.41 C ANISOU 488 CA ARG A 537 4387 4741 6226 -6 -154 145 C ATOM 489 C ARG A 537 -5.960 -29.503 21.781 1.00 38.40 C ANISOU 489 C ARG A 537 4105 4669 5815 92 -249 160 C ATOM 490 O ARG A 537 -5.600 -30.530 21.205 1.00 38.46 O ANISOU 490 O ARG A 537 4066 4665 5881 139 -88 241 O ATOM 491 CB ARG A 537 -4.405 -27.572 22.125 1.00 36.63 C ANISOU 491 CB ARG A 537 3658 4255 6003 -141 -266 78 C ATOM 492 CG ARG A 537 -3.362 -28.645 22.379 1.00 45.35 C ANISOU 492 CG ARG A 537 4502 5456 7275 -140 -271 193 C ATOM 493 CD ARG A 537 -2.205 -28.154 23.177 1.00 46.03 C ANISOU 493 CD ARG A 537 4299 5589 7602 -303 -411 179 C ATOM 494 NE ARG A 537 -2.603 -27.766 24.521 1.00 52.00 N ANISOU 494 NE ARG A 537 5019 6559 8181 -418 -704 24 N ATOM 495 CZ ARG A 537 -1.741 -27.367 25.447 1.00 45.85 C ANISOU 495 CZ ARG A 537 3985 5929 7505 -626 -894 -26 C ATOM 496 NH1 ARG A 537 -0.449 -27.338 25.165 1.00 50.06 N ANISOU 496 NH1 ARG A 537 4261 6395 8364 -703 -835 109 N ATOM 497 NH2 ARG A 537 -2.162 -27.023 26.657 1.00 49.07 N ANISOU 497 NH2 ARG A 537 4382 6585 7677 -784 -1133 -218 N ATOM 498 N THR A 538 -6.711 -29.509 22.875 1.00 36.55 N ANISOU 498 N THR A 538 3886 4588 5414 108 -478 70 N ATOM 499 CA THR A 538 -7.190 -30.743 23.479 1.00 37.48 C ANISOU 499 CA THR A 538 3966 4887 5388 190 -590 120 C ATOM 500 C THR A 538 -7.936 -31.598 22.476 1.00 40.44 C ANISOU 500 C THR A 538 4518 5216 5631 299 -418 174 C ATOM 501 O THR A 538 -7.671 -32.788 22.346 1.00 38.44 O ANISOU 501 O THR A 538 4173 4968 5466 350 -333 252 O ATOM 502 CB THR A 538 -8.123 -30.468 24.662 1.00 38.70 C ANISOU 502 CB THR A 538 4167 5230 5308 170 -821 -4 C ATOM 503 OG1 THR A 538 -7.394 -29.802 25.697 1.00 31.84 O ANISOU 503 OG1 THR A 538 3117 4473 4507 3 -982 -102 O ATOM 504 CG2 THR A 538 -8.694 -31.775 25.213 1.00 30.20 C ANISOU 504 CG2 THR A 538 3056 4343 4077 254 -925 97 C ATOM 505 N LYS A 539 -8.868 -30.992 21.757 1.00 34.19 N ANISOU 505 N LYS A 539 3958 4377 4657 315 -358 140 N ATOM 506 CA LYS A 539 -9.631 -31.743 20.772 1.00 30.31 C ANISOU 506 CA LYS A 539 3637 3907 3973 356 -219 177 C ATOM 507 C LYS A 539 -8.727 -32.273 19.672 1.00 36.88 C ANISOU 507 C LYS A 539 4438 4648 4927 294 66 204 C ATOM 508 O LYS A 539 -8.898 -33.391 19.201 1.00 37.22 O ANISOU 508 O LYS A 539 4512 4710 4922 300 218 171 O ATOM 509 CB LYS A 539 -10.738 -30.878 20.183 1.00 28.70 C ANISOU 509 CB LYS A 539 3633 3706 3566 356 -241 211 C ATOM 510 CG LYS A 539 -11.685 -30.322 21.235 1.00 31.91 C ANISOU 510 CG LYS A 539 4054 4160 3912 421 -454 144 C ATOM 511 CD LYS A 539 -12.180 -31.385 22.187 1.00 41.80 C ANISOU 511 CD LYS A 539 5265 5576 5039 483 -585 87 C ATOM 512 CE LYS A 539 -13.240 -30.816 23.122 1.00 40.81 C ANISOU 512 CE LYS A 539 5173 5522 4812 525 -743 -6 C ATOM 513 NZ LYS A 539 -13.810 -31.844 24.042 1.00 39.50 N ANISOU 513 NZ LYS A 539 4970 5553 4485 568 -867 -30 N ATOM 514 N HIS A 540 -7.766 -31.457 19.261 1.00 34.47 N ANISOU 514 N HIS A 540 4065 4230 4802 217 172 238 N ATOM 515 CA HIS A 540 -6.796 -31.862 18.259 1.00 32.54 C ANISOU 515 CA HIS A 540 3765 3899 4700 139 483 243 C ATOM 516 C HIS A 540 -5.941 -33.035 18.731 1.00 38.44 C ANISOU 516 C HIS A 540 4267 4582 5756 194 571 226 C ATOM 517 O HIS A 540 -5.684 -33.971 17.977 1.00 39.57 O ANISOU 517 O HIS A 540 4400 4661 5973 170 865 161 O ATOM 518 CB HIS A 540 -5.890 -30.694 17.902 1.00 34.14 C ANISOU 518 CB HIS A 540 3902 3989 5080 47 556 307 C ATOM 519 CG HIS A 540 -4.686 -31.091 17.109 1.00 33.17 C ANISOU 519 CG HIS A 540 3653 3773 5178 -32 881 303 C ATOM 520 ND1 HIS A 540 -4.757 -31.414 15.772 1.00 36.54 N ANISOU 520 ND1 HIS A 540 4228 4242 5415 -146 1196 272 N ATOM 521 CD2 HIS A 540 -3.382 -31.209 17.457 1.00 33.03 C ANISOU 521 CD2 HIS A 540 3357 3638 5555 -37 957 322 C ATOM 522 CE1 HIS A 540 -3.549 -31.710 15.328 1.00 39.19 C ANISOU 522 CE1 HIS A 540 4391 4464 6034 -207 1492 237 C ATOM 523 NE2 HIS A 540 -2.696 -31.588 16.329 1.00 46.81 N ANISOU 523 NE2 HIS A 540 5083 5314 7388 -126 1347 288 N ATOM 524 N GLU A 541 -5.494 -32.985 19.979 1.00 32.73 N ANISOU 524 N GLU A 541 3322 3881 5233 246 329 291 N ATOM 525 CA GLU A 541 -4.670 -34.067 20.503 1.00 37.29 C ANISOU 525 CA GLU A 541 3598 4406 6165 304 368 384 C ATOM 526 C GLU A 541 -5.431 -35.378 20.646 1.00 39.25 C ANISOU 526 C GLU A 541 3873 4672 6370 399 399 383 C ATOM 527 O GLU A 541 -4.844 -36.449 20.506 1.00 40.80 O ANISOU 527 O GLU A 541 3863 4720 6918 448 608 434 O ATOM 528 CB GLU A 541 -4.054 -33.661 21.836 1.00 35.69 C ANISOU 528 CB GLU A 541 3132 4314 6116 284 47 508 C ATOM 529 CG GLU A 541 -3.061 -32.511 21.679 1.00 33.58 C ANISOU 529 CG GLU A 541 2768 3982 6010 166 64 499 C ATOM 530 CD GLU A 541 -2.337 -32.204 22.956 1.00 38.54 C ANISOU 530 CD GLU A 541 3098 4759 6786 83 -242 600 C ATOM 531 OE1 GLU A 541 -2.911 -32.471 24.032 1.00 47.13 O ANISOU 531 OE1 GLU A 541 4157 6067 7685 84 -525 633 O ATOM 532 OE2 GLU A 541 -1.205 -31.689 22.880 1.00 44.12 O ANISOU 532 OE2 GLU A 541 3595 5397 7770 -12 -201 649 O ATOM 533 N ILE A 542 -6.733 -35.305 20.896 1.00 35.62 N ANISOU 533 N ILE A 542 3643 4356 5536 425 223 326 N ATOM 534 CA ILE A 542 -7.531 -36.521 20.970 1.00 32.23 C ANISOU 534 CA ILE A 542 3252 3935 5057 495 263 314 C ATOM 535 C ILE A 542 -7.455 -37.274 19.639 1.00 36.29 C ANISOU 535 C ILE A 542 3860 4290 5637 440 678 159 C ATOM 536 O ILE A 542 -7.375 -38.502 19.610 1.00 41.35 O ANISOU 536 O ILE A 542 4377 4794 6538 484 863 143 O ATOM 537 CB ILE A 542 -8.994 -36.211 21.346 1.00 40.83 C ANISOU 537 CB ILE A 542 4579 5212 5721 514 27 267 C ATOM 538 CG1 ILE A 542 -9.119 -36.156 22.865 1.00 35.00 C ANISOU 538 CG1 ILE A 542 3684 4641 4974 560 -310 392 C ATOM 539 CG2 ILE A 542 -9.935 -37.289 20.817 1.00 36.95 C ANISOU 539 CG2 ILE A 542 4225 4710 5106 528 169 184 C ATOM 540 CD1 ILE A 542 -8.873 -37.522 23.520 1.00 37.35 C ANISOU 540 CD1 ILE A 542 3733 4922 5538 632 -325 573 C ATOM 541 N HIS A 543 -7.440 -36.525 18.540 1.00 37.10 N ANISOU 541 N HIS A 543 4162 4412 5522 319 845 46 N ATOM 542 CA HIS A 543 -7.233 -37.102 17.214 1.00 34.83 C ANISOU 542 CA HIS A 543 3966 4041 5228 189 1271 -142 C ATOM 543 C HIS A 543 -5.906 -37.827 17.077 1.00 41.76 C ANISOU 543 C HIS A 543 4553 4665 6649 208 1604 -168 C ATOM 544 O HIS A 543 -5.817 -38.780 16.317 1.00 40.83 O ANISOU 544 O HIS A 543 4439 4417 6657 134 1993 -372 O ATOM 545 CB HIS A 543 -7.307 -36.020 16.136 1.00 31.22 C ANISOU 545 CB HIS A 543 3729 3710 4424 24 1355 -173 C ATOM 546 CG HIS A 543 -8.704 -35.581 15.825 1.00 50.24 C ANISOU 546 CG HIS A 543 6414 6348 6328 -35 1157 -154 C ATOM 547 ND1 HIS A 543 -9.337 -34.566 16.511 1.00 58.41 N ANISOU 547 ND1 HIS A 543 7498 7466 7228 54 798 6 N ATOM 548 CD2 HIS A 543 -9.592 -36.022 14.905 1.00 52.92 C ANISOU 548 CD2 HIS A 543 6964 6853 6289 -191 1278 -272 C ATOM 549 CE1 HIS A 543 -10.556 -34.405 16.029 1.00 57.06 C ANISOU 549 CE1 HIS A 543 7534 7478 6669 -10 702 30 C ATOM 550 NE2 HIS A 543 -10.734 -35.274 15.052 1.00 58.32 N ANISOU 550 NE2 HIS A 543 7796 7721 6643 -171 963 -122 N ATOM 551 N HIS A 544 -4.861 -37.353 17.758 1.00 36.15 N ANISOU 551 N HIS A 544 3575 3879 6283 283 1481 17 N ATOM 552 CA HIS A 544 -3.577 -38.056 17.712 1.00 37.65 C ANISOU 552 CA HIS A 544 3415 3812 7079 326 1778 57 C ATOM 553 C HIS A 544 -3.670 -39.423 18.422 1.00 38.17 C ANISOU 553 C HIS A 544 3236 3720 7547 468 1793 156 C ATOM 554 O HIS A 544 -3.094 -40.408 17.959 1.00 46.86 O ANISOU 554 O HIS A 544 4144 4540 9119 484 2204 69 O ATOM 555 CB HIS A 544 -2.458 -37.223 18.352 1.00 36.69 C ANISOU 555 CB HIS A 544 3022 3686 7232 352 1587 278 C ATOM 556 CG HIS A 544 -1.858 -36.175 17.455 1.00 53.48 C ANISOU 556 CG HIS A 544 5248 5817 9256 213 1765 195 C ATOM 557 ND1 HIS A 544 -1.013 -36.480 16.411 1.00 52.53 N ANISOU 557 ND1 HIS A 544 5046 5523 9392 128 2253 63 N ATOM 558 CD2 HIS A 544 -1.951 -34.821 17.475 1.00 36.40 C ANISOU 558 CD2 HIS A 544 3232 3791 6806 135 1543 239 C ATOM 559 CE1 HIS A 544 -0.621 -35.365 15.817 1.00 40.90 C ANISOU 559 CE1 HIS A 544 3675 4116 7749 -1 2301 60 C ATOM 560 NE2 HIS A 544 -1.168 -34.345 16.447 1.00 48.06 N ANISOU 560 NE2 HIS A 544 4713 5189 8359 9 1872 180 N ATOM 561 N THR A 545 -4.387 -39.493 19.543 1.00 37.60 N ANISOU 561 N THR A 545 3153 3809 7324 562 1373 343 N ATOM 562 CA THR A 545 -4.406 -40.737 20.328 1.00 40.07 C ANISOU 562 CA THR A 545 3182 3987 8056 696 1345 543 C ATOM 563 C THR A 545 -5.478 -41.701 19.849 1.00 39.87 C ANISOU 563 C THR A 545 3364 3879 7906 683 1549 327 C ATOM 564 O THR A 545 -5.415 -42.895 20.130 1.00 37.49 O ANISOU 564 O THR A 545 2905 3366 7973 726 1648 420 O ATOM 565 CB THR A 545 -4.659 -40.490 21.827 1.00 34.66 C ANISOU 565 CB THR A 545 2353 3559 7256 766 810 874 C ATOM 566 OG1 THR A 545 -6.038 -40.149 22.019 1.00 31.55 O ANISOU 566 OG1 THR A 545 2311 3405 6274 736 578 749 O ATOM 567 CG2 THR A 545 -3.766 -39.391 22.383 1.00 35.02 C ANISOU 567 CG2 THR A 545 2240 3767 7299 713 547 1030 C ATOM 568 N GLY A 546 -6.487 -41.175 19.162 1.00 33.41 N ANISOU 568 N GLY A 546 2958 3252 6485 560 1533 70 N ATOM 569 CA GLY A 546 -7.516 -42.025 18.599 1.00 33.37 C ANISOU 569 CA GLY A 546 3160 3213 6306 491 1726 -170 C ATOM 570 C GLY A 546 -8.505 -42.537 19.629 1.00 44.70 C ANISOU 570 C GLY A 546 4581 4746 7657 597 1402 6 C ATOM 571 O GLY A 546 -9.288 -43.449 19.329 1.00 33.82 O ANISOU 571 O GLY A 546 3297 3288 6267 555 1563 -154 O ATOM 572 N GLU A 547 -8.468 -41.964 20.837 1.00 32.96 N ANISOU 572 N GLU A 547 2973 3449 6102 702 965 312 N ATOM 573 CA GLU A 547 -9.370 -42.389 21.901 1.00 32.91 C ANISOU 573 CA GLU A 547 2938 3589 5978 782 653 503 C ATOM 574 C GLU A 547 -10.798 -42.116 21.473 1.00 34.59 C ANISOU 574 C GLU A 547 3525 3990 5625 703 579 282 C ATOM 575 O GLU A 547 -11.080 -41.072 20.895 1.00 33.32 O ANISOU 575 O GLU A 547 3609 3984 5067 619 530 137 O ATOM 576 CB GLU A 547 -9.069 -41.672 23.225 1.00 39.87 C ANISOU 576 CB GLU A 547 3652 4724 6773 833 216 808 C ATOM 577 CG GLU A 547 -10.109 -41.949 24.349 1.00 30.37 C ANISOU 577 CG GLU A 547 2461 3763 5316 870 -114 980 C ATOM 578 CD GLU A 547 -9.676 -41.457 25.733 1.00 37.03 C ANISOU 578 CD GLU A 547 3189 4880 6000 802 -470 1192 C ATOM 579 OE1 GLU A 547 -8.738 -40.641 25.832 1.00 35.79 O ANISOU 579 OE1 GLU A 547 2942 4773 5883 751 -537 1211 O ATOM 580 OE2 GLU A 547 -10.253 -41.915 26.738 1.00 35.66 O ANISOU 580 OE2 GLU A 547 3066 4860 5622 746 -627 1270 O ATOM 581 N ARG A 548 -11.700 -43.049 21.753 1.00 32.67 N ANISOU 581 N ARG A 548 3297 3730 5385 726 569 294 N ATOM 582 CA ARG A 548 -13.109 -42.829 21.442 1.00 34.00 C ANISOU 582 CA ARG A 548 3773 4101 5043 651 463 129 C ATOM 583 C ARG A 548 -13.950 -42.780 22.709 1.00 34.72 C ANISOU 583 C ARG A 548 3829 4411 4951 740 93 349 C ATOM 584 O ARG A 548 -14.332 -43.816 23.236 1.00 39.23 O ANISOU 584 O ARG A 548 4272 4913 5721 787 95 472 O ATOM 585 CB ARG A 548 -13.610 -43.920 20.494 1.00 29.58 C ANISOU 585 CB ARG A 548 3309 3368 4563 534 807 -133 C ATOM 586 CG ARG A 548 -13.157 -43.698 19.050 1.00 35.83 C ANISOU 586 CG ARG A 548 4257 4095 5262 352 1162 -451 C ATOM 587 CD ARG A 548 -13.130 -45.006 18.304 1.00 43.94 C ANISOU 587 CD ARG A 548 5250 4850 6596 225 1612 -737 C ATOM 588 NE ARG A 548 -13.001 -44.811 16.869 1.00 57.48 N ANISOU 588 NE ARG A 548 7176 6622 8042 -36 1946 -1105 N ATOM 589 CZ ARG A 548 -12.754 -45.795 16.010 1.00 75.40 C ANISOU 589 CZ ARG A 548 9433 8661 10555 -218 2442 -1469 C ATOM 590 NH1 ARG A 548 -12.589 -47.043 16.447 1.00 71.54 N ANISOU 590 NH1 ARG A 548 8713 7807 10661 -143 2622 -1457 N ATOM 591 NH2 ARG A 548 -12.651 -45.531 14.715 1.00 90.92 N ANISOU 591 NH2 ARG A 548 11601 10785 12160 -517 2609 -1722 N ATOM 592 N ARG A 549 -14.258 -41.574 23.186 1.00 26.68 N ANISOU 592 N ARG A 549 2917 3646 3573 749 -190 384 N ATOM 593 CA ARG A 549 -14.808 -41.423 24.532 1.00 25.63 C ANISOU 593 CA ARG A 549 2708 3746 3285 808 -509 572 C ATOM 594 C ARG A 549 -16.338 -41.448 24.566 1.00 24.79 C ANISOU 594 C ARG A 549 2798 3795 2827 796 -605 486 C ATOM 595 O ARG A 549 -16.937 -41.626 25.618 1.00 34.86 O ANISOU 595 O ARG A 549 4071 5099 4074 703 -722 540 O ATOM 596 CB ARG A 549 -14.315 -40.118 25.163 1.00 35.85 C ANISOU 596 CB ARG A 549 3981 5216 4424 794 -725 600 C ATOM 597 CG ARG A 549 -12.818 -40.027 25.364 1.00 40.55 C ANISOU 597 CG ARG A 549 4334 5724 5351 789 -703 733 C ATOM 598 CD ARG A 549 -12.433 -38.687 25.969 1.00 36.23 C ANISOU 598 CD ARG A 549 3826 5315 4624 699 -886 658 C ATOM 599 NE ARG A 549 -13.105 -38.442 27.246 1.00 42.01 N ANISOU 599 NE ARG A 549 4694 6109 5159 569 -1030 564 N ATOM 600 CZ ARG A 549 -13.315 -37.232 27.766 1.00 40.17 C ANISOU 600 CZ ARG A 549 4576 5925 4762 459 -1115 435 C ATOM 601 NH1 ARG A 549 -12.913 -36.145 27.123 1.00 36.02 N ANISOU 601 NH1 ARG A 549 4056 5427 4204 460 -1103 365 N ATOM 602 NH2 ARG A 549 -13.935 -37.106 28.927 1.00 35.86 N ANISOU 602 NH2 ARG A 549 4109 5424 4092 367 -1181 383 N ATOM 603 N TYR A 550 -16.963 -41.228 23.419 1.00 19.69 N ANISOU 603 N TYR A 550 2377 3121 1983 726 -476 280 N ATOM 604 CA TYR A 550 -18.412 -41.091 23.369 1.00 27.44 C ANISOU 604 CA TYR A 550 3518 4257 2652 695 -579 222 C ATOM 605 C TYR A 550 -19.016 -42.390 22.900 1.00 34.49 C ANISOU 605 C TYR A 550 4427 5069 3608 642 -428 157 C ATOM 606 O TYR A 550 -18.769 -42.814 21.767 1.00 37.39 O ANISOU 606 O TYR A 550 4871 5306 4030 522 -180 -21 O ATOM 607 CB TYR A 550 -18.824 -39.945 22.433 1.00 20.64 C ANISOU 607 CB TYR A 550 2827 3372 1643 550 -526 106 C ATOM 608 CG TYR A 550 -18.472 -38.583 22.997 1.00 30.96 C ANISOU 608 CG TYR A 550 4097 4614 3052 501 -581 139 C ATOM 609 CD1 TYR A 550 -19.438 -37.804 23.651 1.00 24.91 C ANISOU 609 CD1 TYR A 550 3330 3792 2344 395 -604 147 C ATOM 610 CD2 TYR A 550 -17.175 -38.093 22.919 1.00 27.05 C ANISOU 610 CD2 TYR A 550 3561 4145 2572 602 -608 151 C ATOM 611 CE1 TYR A 550 -19.125 -36.584 24.180 1.00 37.42 C ANISOU 611 CE1 TYR A 550 4891 5376 3952 412 -642 131 C ATOM 612 CE2 TYR A 550 -16.848 -36.851 23.455 1.00 37.02 C ANISOU 612 CE2 TYR A 550 4796 5375 3897 560 -667 151 C ATOM 613 CZ TYR A 550 -17.830 -36.101 24.080 1.00 35.67 C ANISOU 613 CZ TYR A 550 4643 5166 3744 459 -678 132 C ATOM 614 OH TYR A 550 -17.525 -34.877 24.618 1.00 28.88 O ANISOU 614 OH TYR A 550 3760 4316 2895 469 -734 94 O ATOM 615 N GLN A 551 -19.796 -43.031 23.762 1.00 26.48 N ANISOU 615 N GLN A 551 3336 4129 2595 690 -546 275 N ATOM 616 CA GLN A 551 -20.345 -44.342 23.402 1.00 38.22 C ANISOU 616 CA GLN A 551 4808 5485 4229 619 -378 211 C ATOM 617 C GLN A 551 -21.870 -44.337 23.330 1.00 27.84 C ANISOU 617 C GLN A 551 3621 4365 2593 563 -500 162 C ATOM 618 O GLN A 551 -22.541 -43.965 24.278 1.00 31.13 O ANISOU 618 O GLN A 551 4006 4748 3075 496 -594 254 O ATOM 619 CB GLN A 551 -19.870 -45.425 24.389 1.00 26.37 C ANISOU 619 CB GLN A 551 3043 3831 3145 707 -355 451 C ATOM 620 CG GLN A 551 -20.337 -46.836 24.003 1.00 29.95 C ANISOU 620 CG GLN A 551 3448 4053 3877 632 -124 374 C ATOM 621 CD GLN A 551 -19.770 -47.894 24.916 1.00 33.87 C ANISOU 621 CD GLN A 551 3633 4341 4894 732 -79 688 C ATOM 622 OE1 GLN A 551 -19.412 -47.602 26.055 1.00 34.45 O ANISOU 622 OE1 GLN A 551 3540 4581 4968 836 -319 1018 O ATOM 623 NE2 GLN A 551 -19.668 -49.134 24.419 1.00 32.07 N ANISOU 623 NE2 GLN A 551 3303 3751 5132 677 241 597 N ATOM 624 N CYS A 552 -22.402 -44.756 22.192 1.00 29.92 N ANISOU 624 N CYS A 552 4015 4605 2749 393 -346 -52 N ATOM 625 CA CYS A 552 -23.839 -44.943 22.043 1.00 32.77 C ANISOU 625 CA CYS A 552 4452 5136 2863 303 -448 -84 C ATOM 626 C CYS A 552 -24.327 -46.079 22.942 1.00 41.36 C ANISOU 626 C CYS A 552 5393 6145 4177 353 -449 31 C ATOM 627 O CYS A 552 -23.844 -47.211 22.842 1.00 39.75 O ANISOU 627 O CYS A 552 5089 5672 4341 309 -220 -20 O ATOM 628 CB CYS A 552 -24.190 -45.225 20.584 1.00 31.77 C ANISOU 628 CB CYS A 552 4478 5055 2538 42 -285 -347 C ATOM 629 SG CYS A 552 -25.907 -45.702 20.332 1.00 30.14 S ANISOU 629 SG CYS A 552 4321 4834 2298 -94 -364 -330 S ATOM 630 N LEU A 553 -25.279 -45.773 23.824 1.00 33.83 N ANISOU 630 N LEU A 553 3819 4173 4863 -79 4 709 N ATOM 631 CA LEU A 553 -25.765 -46.752 24.773 1.00 32.78 C ANISOU 631 CA LEU A 553 3716 4079 4659 -406 -147 957 C ATOM 632 C LEU A 553 -26.818 -47.647 24.159 1.00 35.46 C ANISOU 632 C LEU A 553 4032 4375 5065 -529 -223 993 C ATOM 633 O LEU A 553 -27.227 -48.623 24.773 1.00 40.09 O ANISOU 633 O LEU A 553 4665 4945 5622 -847 -415 1238 O ATOM 634 CB LEU A 553 -26.324 -46.078 26.025 1.00 39.57 C ANISOU 634 CB LEU A 553 4524 5334 5175 -633 9 1004 C ATOM 635 CG LEU A 553 -25.274 -45.471 26.959 1.00 50.29 C ANISOU 635 CG LEU A 553 5975 6727 6405 -675 -5 1052 C ATOM 636 CD1 LEU A 553 -25.923 -44.917 28.212 1.00 49.91 C ANISOU 636 CD1 LEU A 553 5903 7105 5958 -958 173 1038 C ATOM 637 CD2 LEU A 553 -24.218 -46.523 27.308 1.00 45.95 C ANISOU 637 CD2 LEU A 553 5529 5880 6050 -799 -350 1349 C ATOM 638 N ALA A 554 -27.259 -47.340 22.946 1.00 38.41 N ANISOU 638 N ALA A 554 4350 4734 5510 -340 -117 791 N ATOM 639 CA ALA A 554 -28.264 -48.204 22.313 1.00 41.59 C ANISOU 639 CA ALA A 554 4749 5098 5957 -504 -220 839 C ATOM 640 C ALA A 554 -27.642 -49.426 21.612 1.00 44.17 C ANISOU 640 C ALA A 554 5265 4966 6552 -477 -466 815 C ATOM 641 O ALA A 554 -28.256 -50.488 21.576 1.00 54.55 O ANISOU 641 O ALA A 554 6669 6142 7918 -726 -674 952 O ATOM 642 CB ALA A 554 -29.114 -47.395 21.317 1.00 33.82 C ANISOU 642 CB ALA A 554 3620 4309 4921 -378 -52 671 C ATOM 643 N CYS A 555 -26.437 -49.281 21.050 1.00 42.62 N ANISOU 643 N CYS A 555 5121 4541 6532 -183 -444 621 N ATOM 644 CA CYS A 555 -25.818 -50.389 20.303 1.00 38.30 C ANISOU 644 CA CYS A 555 4715 3564 6274 -79 -623 481 C ATOM 645 C CYS A 555 -24.346 -50.617 20.661 1.00 38.45 C ANISOU 645 C CYS A 555 4732 3326 6553 151 -714 456 C ATOM 646 O CYS A 555 -23.744 -51.600 20.230 1.00 47.85 O ANISOU 646 O CYS A 555 6001 4117 8061 291 -880 323 O ATOM 647 CB CYS A 555 -25.928 -50.150 18.804 1.00 32.82 C ANISOU 647 CB CYS A 555 4029 2893 5550 58 -472 158 C ATOM 648 SG CYS A 555 -24.896 -48.784 18.218 1.00 34.04 S ANISOU 648 SG CYS A 555 4046 3275 5611 348 -201 -63 S ATOM 649 N GLY A 556 -23.769 -49.699 21.431 1.00 32.52 N ANISOU 649 N GLY A 556 3877 2795 5684 199 -614 565 N ATOM 650 CA GLY A 556 -22.419 -49.861 21.930 1.00 31.51 C ANISOU 650 CA GLY A 556 3702 2485 5785 358 -739 629 C ATOM 651 C GLY A 556 -21.304 -49.177 21.137 1.00 33.10 C ANISOU 651 C GLY A 556 3764 2761 6050 674 -545 361 C ATOM 652 O GLY A 556 -20.157 -49.145 21.594 1.00 34.76 O ANISOU 652 O GLY A 556 3870 2906 6429 799 -629 440 O ATOM 653 N LYS A 557 -21.621 -48.679 19.943 1.00 28.98 N ANISOU 653 N LYS A 557 3224 2399 5386 757 -317 79 N ATOM 654 CA LYS A 557 -20.628 -48.006 19.098 1.00 37.57 C ANISOU 654 CA LYS A 557 4174 3646 6455 964 -127 -160 C ATOM 655 C LYS A 557 -20.031 -46.807 19.789 1.00 35.42 C ANISOU 655 C LYS A 557 3820 3623 6014 940 -69 10 C ATOM 656 O LYS A 557 -20.747 -46.020 20.429 1.00 35.15 O ANISOU 656 O LYS A 557 3859 3752 5745 777 -41 168 O ATOM 657 CB LYS A 557 -21.240 -47.544 17.773 1.00 36.97 C ANISOU 657 CB LYS A 557 4125 3765 6155 925 63 -403 C ATOM 658 CG LYS A 557 -21.263 -48.583 16.664 1.00 53.77 C ANISOU 658 CG LYS A 557 6307 5706 8417 996 78 -729 C ATOM 659 CD LYS A 557 -21.140 -47.880 15.316 1.00 65.25 C ANISOU 659 CD LYS A 557 7711 7474 9606 962 300 -988 C ATOM 660 CE LYS A 557 -21.071 -48.865 14.171 1.00 70.94 C ANISOU 660 CE LYS A 557 8496 8069 10389 1003 364 -1393 C ATOM 661 NZ LYS A 557 -22.286 -49.704 14.137 1.00 71.73 N ANISOU 661 NZ LYS A 557 8818 7914 10523 834 195 -1350 N ATOM 662 N SER A 558 -18.725 -46.638 19.634 1.00 40.96 N ANISOU 662 N SER A 558 4356 4372 6833 1099 -42 -53 N ATOM 663 CA SER A 558 -18.048 -45.473 20.194 1.00 32.90 C ANISOU 663 CA SER A 558 3274 3587 5637 1034 -15 110 C ATOM 664 C SER A 558 -17.592 -44.454 19.145 1.00 38.14 C ANISOU 664 C SER A 558 3849 4547 6095 1044 173 -56 C ATOM 665 O SER A 558 -17.310 -44.808 18.002 1.00 43.10 O ANISOU 665 O SER A 558 4371 5242 6763 1143 298 -319 O ATOM 666 CB SER A 558 -16.855 -45.931 21.015 1.00 33.18 C ANISOU 666 CB SER A 558 3163 3513 5932 1113 -195 288 C ATOM 667 OG SER A 558 -17.294 -46.757 22.069 1.00 35.05 O ANISOU 667 OG SER A 558 3514 3496 6305 1005 -433 528 O ATOM 668 N PHE A 559 -17.481 -43.193 19.561 1.00 32.59 N ANISOU 668 N PHE A 559 3204 4023 5156 904 172 98 N ATOM 669 CA PHE A 559 -17.167 -42.083 18.652 1.00 28.12 C ANISOU 669 CA PHE A 559 2607 3717 4361 819 270 31 C ATOM 670 C PHE A 559 -16.141 -41.162 19.289 1.00 32.12 C ANISOU 670 C PHE A 559 3073 4361 4770 714 188 226 C ATOM 671 O PHE A 559 -16.021 -41.119 20.530 1.00 26.43 O ANISOU 671 O PHE A 559 2429 3535 4079 665 64 415 O ATOM 672 CB PHE A 559 -18.462 -41.338 18.284 1.00 29.25 C ANISOU 672 CB PHE A 559 2936 3861 4315 714 287 18 C ATOM 673 CG PHE A 559 -19.493 -42.254 17.712 1.00 29.76 C ANISOU 673 CG PHE A 559 3033 3816 4457 760 332 -124 C ATOM 674 CD1 PHE A 559 -19.513 -42.527 16.351 1.00 30.83 C ANISOU 674 CD1 PHE A 559 3119 4066 4528 735 422 -323 C ATOM 675 CD2 PHE A 559 -20.365 -42.942 18.546 1.00 29.92 C ANISOU 675 CD2 PHE A 559 3132 3652 4584 775 276 -55 C ATOM 676 CE1 PHE A 559 -20.424 -43.431 15.817 1.00 30.27 C ANISOU 676 CE1 PHE A 559 3108 3880 4511 735 436 -458 C ATOM 677 CE2 PHE A 559 -21.275 -43.848 18.024 1.00 26.10 C ANISOU 677 CE2 PHE A 559 2683 3067 4168 768 280 -154 C ATOM 678 CZ PHE A 559 -21.309 -44.088 16.658 1.00 33.14 C ANISOU 678 CZ PHE A 559 3555 4026 5011 756 350 -360 C ATOM 679 N ILE A 560 -15.370 -40.461 18.455 1.00 31.04 N ANISOU 679 N ILE A 560 2819 4491 4483 620 239 200 N ATOM 680 CA ILE A 560 -14.331 -39.597 18.985 1.00 33.46 C ANISOU 680 CA ILE A 560 3080 4951 4683 466 131 411 C ATOM 681 C ILE A 560 -14.932 -38.336 19.609 1.00 28.70 C ANISOU 681 C ILE A 560 2793 4238 3874 283 1 556 C ATOM 682 O ILE A 560 -14.323 -37.767 20.515 1.00 31.23 O ANISOU 682 O ILE A 560 3183 4558 4124 149 -133 739 O ATOM 683 CB ILE A 560 -13.274 -39.176 17.923 1.00 39.96 C ANISOU 683 CB ILE A 560 3657 6162 5362 343 209 376 C ATOM 684 CG1 ILE A 560 -13.898 -38.345 16.815 1.00 54.75 C ANISOU 684 CG1 ILE A 560 5676 8164 6963 144 235 324 C ATOM 685 CG2 ILE A 560 -12.547 -40.379 17.339 1.00 38.88 C ANISOU 685 CG2 ILE A 560 3153 6170 5451 570 381 146 C ATOM 686 CD1 ILE A 560 -12.849 -37.676 15.932 1.00 61.87 C ANISOU 686 CD1 ILE A 560 6381 9513 7614 -126 258 385 C ATOM 687 N ASN A 561 -16.108 -37.904 19.148 1.00 25.03 N ANISOU 687 N ASN A 561 2509 3665 3334 282 23 463 N ATOM 688 CA ASN A 561 -16.677 -36.657 19.673 1.00 36.32 C ANISOU 688 CA ASN A 561 4212 4945 4642 177 -104 536 C ATOM 689 C ASN A 561 -18.199 -36.637 19.740 1.00 37.56 C ANISOU 689 C ASN A 561 4497 4910 4863 306 -60 411 C ATOM 690 O ASN A 561 -18.863 -37.555 19.268 1.00 31.38 O ANISOU 690 O ASN A 561 3614 4129 4179 421 47 308 O ATOM 691 CB ASN A 561 -16.186 -35.461 18.853 1.00 26.40 C ANISOU 691 CB ASN A 561 3016 3802 3211 -48 -241 643 C ATOM 692 CG ASN A 561 -16.601 -35.526 17.392 1.00 28.76 C ANISOU 692 CG ASN A 561 3233 4236 3457 -94 -199 578 C ATOM 693 OD1 ASN A 561 -17.676 -36.029 17.045 1.00 35.41 O ANISOU 693 OD1 ASN A 561 4085 4977 4394 45 -123 451 O ATOM 694 ND2 ASN A 561 -15.747 -35.002 16.522 1.00 25.00 N ANISOU 694 ND2 ASN A 561 2674 4034 2790 -354 -265 689 N ATOM 695 N TYR A 562 -18.740 -35.579 20.340 1.00 33.59 N ANISOU 695 N TYR A 562 4205 4241 4315 289 -150 403 N ATOM 696 CA TYR A 562 -20.178 -35.450 20.538 1.00 27.74 C ANISOU 696 CA TYR A 562 3520 3354 3666 444 -95 263 C ATOM 697 C TYR A 562 -20.911 -35.460 19.208 1.00 35.80 C ANISOU 697 C TYR A 562 4456 4386 4762 483 -125 252 C ATOM 698 O TYR A 562 -21.962 -36.098 19.062 1.00 38.32 O ANISOU 698 O TYR A 562 4678 4702 5179 598 -32 171 O ATOM 699 CB TYR A 562 -20.511 -34.165 21.306 1.00 31.44 C ANISOU 699 CB TYR A 562 4212 3624 4110 458 -188 188 C ATOM 700 CG TYR A 562 -21.984 -33.972 21.600 1.00 29.73 C ANISOU 700 CG TYR A 562 3978 3296 4024 669 -98 -8 C ATOM 701 CD1 TYR A 562 -22.500 -34.245 22.857 1.00 26.05 C ANISOU 701 CD1 TYR A 562 3520 2880 3499 723 78 -168 C ATOM 702 CD2 TYR A 562 -22.859 -33.508 20.615 1.00 28.41 C ANISOU 702 CD2 TYR A 562 3748 3018 4028 785 -199 -17 C ATOM 703 CE1 TYR A 562 -23.853 -34.075 23.134 1.00 28.13 C ANISOU 703 CE1 TYR A 562 3688 3128 3872 919 205 -378 C ATOM 704 CE2 TYR A 562 -24.209 -33.335 20.879 1.00 30.00 C ANISOU 704 CE2 TYR A 562 3852 3149 4400 1009 -121 -191 C ATOM 705 CZ TYR A 562 -24.709 -33.622 22.138 1.00 33.58 C ANISOU 705 CZ TYR A 562 4270 3695 4795 1093 108 -394 C ATOM 706 OH TYR A 562 -26.062 -33.432 22.394 1.00 29.73 O ANISOU 706 OH TYR A 562 3610 3216 4470 1320 225 -596 O ATOM 707 N GLN A 563 -20.354 -34.743 18.241 1.00 31.52 N ANISOU 707 N GLN A 563 3949 3886 4141 322 -282 367 N ATOM 708 CA GLN A 563 -21.019 -34.538 16.960 1.00 28.93 C ANISOU 708 CA GLN A 563 3582 3578 3832 264 -384 413 C ATOM 709 C GLN A 563 -21.225 -35.846 16.196 1.00 33.20 C ANISOU 709 C GLN A 563 3948 4315 4353 266 -216 332 C ATOM 710 O GLN A 563 -22.312 -36.088 15.673 1.00 39.26 O ANISOU 710 O GLN A 563 4673 5049 5196 308 -233 309 O ATOM 711 CB GLN A 563 -20.230 -33.534 16.115 1.00 27.19 C ANISOU 711 CB GLN A 563 3450 3423 3458 -20 -618 606 C ATOM 712 CG GLN A 563 -20.344 -32.096 16.599 1.00 36.03 C ANISOU 712 CG GLN A 563 4807 4227 4656 -39 -892 695 C ATOM 713 CD GLN A 563 -19.376 -31.750 17.722 1.00 38.67 C ANISOU 713 CD GLN A 563 5269 4515 4907 -83 -885 690 C ATOM 714 OE1 GLN A 563 -18.553 -32.568 18.138 1.00 31.98 O ANISOU 714 OE1 GLN A 563 4298 3895 3958 -108 -699 671 O ATOM 715 NE2 GLN A 563 -19.471 -30.521 18.214 1.00 36.81 N ANISOU 715 NE2 GLN A 563 5291 3956 4738 -99 -1125 710 N ATOM 716 N PHE A 564 -20.206 -36.700 16.131 1.00 29.89 N ANISOU 716 N PHE A 564 3418 4082 3857 230 -71 277 N ATOM 717 CA PHE A 564 -20.386 -37.978 15.425 1.00 36.51 C ANISOU 717 CA PHE A 564 4127 5036 4708 261 83 128 C ATOM 718 C PHE A 564 -21.340 -38.880 16.210 1.00 33.24 C ANISOU 718 C PHE A 564 3711 4446 4474 447 158 52 C ATOM 719 O PHE A 564 -22.165 -39.587 15.631 1.00 37.13 O ANISOU 719 O PHE A 564 4176 4934 4999 444 189 -21 O ATOM 720 CB PHE A 564 -19.044 -38.691 15.199 1.00 40.65 C ANISOU 720 CB PHE A 564 4494 5764 5186 248 221 28 C ATOM 721 CG PHE A 564 -18.102 -37.947 14.280 1.00 45.75 C ANISOU 721 CG PHE A 564 5076 6717 5590 -6 189 91 C ATOM 722 CD1 PHE A 564 -18.593 -37.150 13.258 1.00 52.93 C ANISOU 722 CD1 PHE A 564 6076 7728 6308 -261 50 195 C ATOM 723 CD2 PHE A 564 -16.725 -38.038 14.452 1.00 41.41 C ANISOU 723 CD2 PHE A 564 4350 6383 5001 -30 267 87 C ATOM 724 CE1 PHE A 564 -17.725 -36.462 12.416 1.00 56.36 C ANISOU 724 CE1 PHE A 564 6456 8495 6461 -591 -8 302 C ATOM 725 CE2 PHE A 564 -15.852 -37.364 13.619 1.00 40.28 C ANISOU 725 CE2 PHE A 564 4107 6608 4591 -323 251 163 C ATOM 726 CZ PHE A 564 -16.350 -36.573 12.599 1.00 51.30 C ANISOU 726 CZ PHE A 564 5624 8125 5742 -632 114 275 C ATOM 727 N MET A 565 -21.218 -38.852 17.534 1.00 29.62 N ANISOU 727 N MET A 565 3290 3874 4090 546 171 92 N ATOM 728 CA MET A 565 -22.112 -39.607 18.408 1.00 23.49 C ANISOU 728 CA MET A 565 2509 2997 3421 636 227 68 C ATOM 729 C MET A 565 -23.562 -39.174 18.178 1.00 32.88 C ANISOU 729 C MET A 565 3692 4161 4642 664 203 58 C ATOM 730 O MET A 565 -24.438 -40.017 18.014 1.00 30.82 O ANISOU 730 O MET A 565 3364 3909 4436 660 237 34 O ATOM 731 CB MET A 565 -21.722 -39.401 19.880 1.00 24.59 C ANISOU 731 CB MET A 565 2709 3090 3542 644 228 132 C ATOM 732 CG MET A 565 -22.702 -39.974 20.922 1.00 22.12 C ANISOU 732 CG MET A 565 2394 2761 3248 646 287 133 C ATOM 733 SD MET A 565 -24.195 -38.984 21.252 1.00 37.32 S ANISOU 733 SD MET A 565 4311 4719 5150 718 352 33 S ATOM 734 CE MET A 565 -23.502 -37.459 21.897 1.00 32.11 C ANISOU 734 CE MET A 565 3823 3982 4396 733 303 -15 C ATOM 735 N SER A 566 -23.810 -37.860 18.188 1.00 26.07 N ANISOU 735 N SER A 566 2887 3245 3775 691 113 86 N ATOM 736 CA SER A 566 -25.173 -37.341 18.031 1.00 30.39 C ANISOU 736 CA SER A 566 3367 3744 4436 781 63 73 C ATOM 737 C SER A 566 -25.725 -37.651 16.645 1.00 33.55 C ANISOU 737 C SER A 566 3693 4206 4848 679 -35 140 C ATOM 738 O SER A 566 -26.893 -38.000 16.479 1.00 36.94 O ANISOU 738 O SER A 566 3997 4669 5370 707 -38 150 O ATOM 739 CB SER A 566 -25.208 -35.830 18.274 1.00 26.94 C ANISOU 739 CB SER A 566 3026 3145 4067 867 -72 70 C ATOM 740 OG SER A 566 -26.496 -35.301 18.021 1.00 35.98 O ANISOU 740 OG SER A 566 4051 4211 5407 1008 -155 53 O ATOM 741 N SER A 567 -24.869 -37.488 15.649 1.00 38.80 N ANISOU 741 N SER A 567 4425 4934 5382 513 -118 194 N ATOM 742 CA SER A 567 -25.200 -37.780 14.260 1.00 35.59 C ANISOU 742 CA SER A 567 3990 4646 4888 322 -208 245 C ATOM 743 C SER A 567 -25.665 -39.233 14.114 1.00 35.94 C ANISOU 743 C SER A 567 3975 4751 4930 302 -74 133 C ATOM 744 O SER A 567 -26.654 -39.534 13.440 1.00 40.34 O ANISOU 744 O SER A 567 4482 5349 5495 201 -157 181 O ATOM 745 CB SER A 567 -23.967 -37.516 13.388 1.00 38.61 C ANISOU 745 CB SER A 567 4438 5189 5044 100 -238 266 C ATOM 746 OG SER A 567 -24.320 -37.288 12.046 1.00 55.19 O ANISOU 746 OG SER A 567 6547 7425 6998 -168 -397 370 O ATOM 747 N HIS A 568 -24.932 -40.124 14.769 1.00 30.41 N ANISOU 747 N HIS A 568 3289 4027 4238 381 86 10 N ATOM 748 CA HIS A 568 -25.217 -41.549 14.738 1.00 30.92 C ANISOU 748 CA HIS A 568 3347 4057 4344 365 162 -96 C ATOM 749 C HIS A 568 -26.570 -41.858 15.362 1.00 37.60 C ANISOU 749 C HIS A 568 4125 4863 5297 385 133 -9 C ATOM 750 O HIS A 568 -27.394 -42.565 14.781 1.00 38.76 O ANISOU 750 O HIS A 568 4258 5031 5438 258 81 -4 O ATOM 751 CB HIS A 568 -24.122 -42.333 15.469 1.00 23.57 C ANISOU 751 CB HIS A 568 2431 3039 3485 474 262 -192 C ATOM 752 CG HIS A 568 -24.545 -43.712 15.871 1.00 25.64 C ANISOU 752 CG HIS A 568 2716 3152 3875 481 259 -233 C ATOM 753 ND1 HIS A 568 -24.488 -44.787 15.008 1.00 26.64 N ANISOU 753 ND1 HIS A 568 2896 3205 4022 423 260 -409 N ATOM 754 CD2 HIS A 568 -25.060 -44.189 17.030 1.00 24.77 C ANISOU 754 CD2 HIS A 568 2603 2950 3859 490 227 -116 C ATOM 755 CE1 HIS A 568 -24.940 -45.866 15.624 1.00 35.28 C ANISOU 755 CE1 HIS A 568 4040 4105 5261 411 187 -373 C ATOM 756 NE2 HIS A 568 -25.295 -45.531 16.852 1.00 36.24 N ANISOU 756 NE2 HIS A 568 4116 4242 5410 424 163 -168 N ATOM 757 N ILE A 569 -26.799 -41.317 16.549 1.00 35.41 N ANISOU 757 N ILE A 569 3798 4569 5089 512 172 48 N ATOM 758 CA ILE A 569 -27.988 -41.655 17.296 1.00 30.37 C ANISOU 758 CA ILE A 569 3040 3987 4512 512 202 103 C ATOM 759 C ILE A 569 -29.233 -41.113 16.596 1.00 36.77 C ANISOU 759 C ILE A 569 3698 4888 5386 497 106 177 C ATOM 760 O ILE A 569 -30.258 -41.809 16.519 1.00 33.08 O ANISOU 760 O ILE A 569 3112 4517 4941 386 83 244 O ATOM 761 CB ILE A 569 -27.871 -41.151 18.739 1.00 27.72 C ANISOU 761 CB ILE A 569 2682 3679 4171 619 309 87 C ATOM 762 CG1 ILE A 569 -26.813 -41.978 19.479 1.00 28.02 C ANISOU 762 CG1 ILE A 569 2842 3641 4165 562 336 99 C ATOM 763 CG2 ILE A 569 -29.175 -41.302 19.483 1.00 25.18 C ANISOU 763 CG2 ILE A 569 2173 3530 3864 599 387 111 C ATOM 764 CD1 ILE A 569 -26.645 -41.582 20.945 1.00 31.24 C ANISOU 764 CD1 ILE A 569 3263 4116 4490 566 421 109 C ATOM 765 N LYS A 570 -29.138 -39.903 16.049 1.00 33.03 N ANISOU 765 N LYS A 570 3221 4374 4955 573 2 206 N ATOM 766 CA LYS A 570 -30.265 -39.318 15.329 1.00 35.35 C ANISOU 766 CA LYS A 570 3349 4709 5372 568 -167 327 C ATOM 767 C LYS A 570 -30.559 -40.131 14.078 1.00 36.33 C ANISOU 767 C LYS A 570 3509 4911 5384 293 -289 411 C ATOM 768 O LYS A 570 -31.709 -40.431 13.775 1.00 44.26 O ANISOU 768 O LYS A 570 4345 6015 6455 204 -382 525 O ATOM 769 CB LYS A 570 -30.000 -37.853 14.956 1.00 29.60 C ANISOU 769 CB LYS A 570 2659 3844 4745 670 -346 387 C ATOM 770 CG LYS A 570 -30.037 -36.872 16.135 1.00 44.10 C ANISOU 770 CG LYS A 570 4455 5559 6742 961 -270 266 C ATOM 771 CD LYS A 570 -29.752 -35.404 15.692 1.00 41.68 C ANISOU 771 CD LYS A 570 4244 5014 6577 1041 -534 343 C ATOM 772 CE LYS A 570 -29.798 -34.431 16.871 1.00 40.79 C ANISOU 772 CE LYS A 570 4138 4724 6636 1341 -461 148 C ATOM 773 NZ LYS A 570 -29.459 -33.014 16.496 1.00 58.42 N ANISOU 773 NZ LYS A 570 6526 6632 9038 1405 -776 224 N ATOM 774 N SER A 571 -29.507 -40.513 13.369 1.00 38.70 N ANISOU 774 N SER A 571 4012 5196 5495 141 -275 333 N ATOM 775 CA SER A 571 -29.659 -41.212 12.104 1.00 34.97 C ANISOU 775 CA SER A 571 3621 4811 4853 -151 -367 336 C ATOM 776 C SER A 571 -30.029 -42.691 12.279 1.00 37.11 C ANISOU 776 C SER A 571 3934 5063 5104 -249 -289 240 C ATOM 777 O SER A 571 -30.953 -43.186 11.647 1.00 41.30 O ANISOU 777 O SER A 571 4437 5663 5591 -468 -417 325 O ATOM 778 CB SER A 571 -28.369 -41.092 11.304 1.00 42.58 C ANISOU 778 CB SER A 571 4754 5828 5596 -279 -327 214 C ATOM 779 OG SER A 571 -28.398 -41.963 10.194 1.00 63.14 O ANISOU 779 OG SER A 571 7464 8539 7986 -563 -336 102 O ATOM 780 N VAL A 572 -29.301 -43.404 13.127 1.00 36.67 N ANISOU 780 N VAL A 572 3957 4887 5087 -121 -131 94 N ATOM 781 CA VAL A 572 -29.525 -44.841 13.257 1.00 32.91 C ANISOU 781 CA VAL A 572 3575 4305 4624 -236 -129 18 C ATOM 782 C VAL A 572 -30.654 -45.155 14.232 1.00 33.67 C ANISOU 782 C VAL A 572 3519 4449 4824 -262 -162 200 C ATOM 783 O VAL A 572 -31.451 -46.064 13.995 1.00 38.62 O ANISOU 783 O VAL A 572 4168 5076 5432 -487 -269 266 O ATOM 784 CB VAL A 572 -28.234 -45.573 13.706 1.00 31.85 C ANISOU 784 CB VAL A 572 3579 3978 4546 -100 -16 -182 C ATOM 785 CG1 VAL A 572 -28.479 -47.100 13.870 1.00 27.80 C ANISOU 785 CG1 VAL A 572 3199 3245 4119 -212 -94 -245 C ATOM 786 CG2 VAL A 572 -27.125 -45.337 12.693 1.00 27.52 C ANISOU 786 CG2 VAL A 572 3110 3477 3869 -92 64 -402 C ATOM 787 N HIS A 573 -30.745 -44.392 15.315 1.00 32.79 N ANISOU 787 N HIS A 573 3253 4415 4791 -74 -68 272 N ATOM 788 CA HIS A 573 -31.711 -44.707 16.361 1.00 29.65 C ANISOU 788 CA HIS A 573 2678 4156 4433 -125 -37 402 C ATOM 789 C HIS A 573 -32.926 -43.763 16.415 1.00 34.03 C ANISOU 789 C HIS A 573 2910 4956 5063 -54 -36 508 C ATOM 790 O HIS A 573 -33.821 -43.959 17.239 1.00 36.43 O ANISOU 790 O HIS A 573 2988 5477 5376 -107 32 589 O ATOM 791 CB HIS A 573 -30.990 -44.737 17.709 1.00 26.22 C ANISOU 791 CB HIS A 573 2288 3681 3995 -15 94 367 C ATOM 792 CG HIS A 573 -29.909 -45.772 17.775 1.00 36.73 C ANISOU 792 CG HIS A 573 3864 4752 5342 -63 40 309 C ATOM 793 ND1 HIS A 573 -30.131 -47.102 17.479 1.00 35.64 N ANISOU 793 ND1 HIS A 573 3854 4455 5231 -272 -105 342 N ATOM 794 CD2 HIS A 573 -28.596 -45.672 18.088 1.00 24.79 C ANISOU 794 CD2 HIS A 573 2472 3083 3865 86 83 218 C ATOM 795 CE1 HIS A 573 -28.997 -47.773 17.610 1.00 34.46 C ANISOU 795 CE1 HIS A 573 3887 4027 5181 -198 -148 247 C ATOM 796 NE2 HIS A 573 -28.051 -46.929 17.980 1.00 38.09 N ANISOU 796 NE2 HIS A 573 4315 4513 5644 18 -29 184 N ATOM 797 N SER A 574 -32.962 -42.766 15.526 1.00 36.62 N ANISOU 797 N SER A 574 3194 5264 5457 47 -131 517 N ATOM 798 CA SER A 574 -34.060 -41.785 15.469 1.00 41.14 C ANISOU 798 CA SER A 574 3439 5988 6206 180 -195 618 C ATOM 799 C SER A 574 -34.390 -41.225 16.831 1.00 37.53 C ANISOU 799 C SER A 574 2758 5657 5844 427 15 514 C ATOM 800 O SER A 574 -35.556 -41.153 17.224 1.00 39.26 O ANISOU 800 O SER A 574 2622 6129 6166 461 64 562 O ATOM 801 CB SER A 574 -35.333 -42.392 14.872 1.00 44.74 C ANISOU 801 CB SER A 574 3683 6635 6681 -65 -350 816 C ATOM 802 OG SER A 574 -35.167 -42.690 13.499 1.00 65.12 O ANISOU 802 OG SER A 574 6462 9128 9152 -317 -568 896 O ATOM 803 N GLN A 575 -33.353 -40.855 17.561 1.00 34.08 N ANISOU 803 N GLN A 575 2512 5088 5347 572 153 357 N ATOM 804 CA GLN A 575 -33.523 -40.253 18.872 1.00 36.83 C ANISOU 804 CA GLN A 575 2717 5556 5720 773 369 199 C ATOM 805 C GLN A 575 -32.552 -39.085 19.018 1.00 38.13 C ANISOU 805 C GLN A 575 3076 5474 5937 1004 366 55 C ATOM 806 O GLN A 575 -31.566 -38.993 18.286 1.00 39.20 O ANISOU 806 O GLN A 575 3467 5401 6026 947 231 106 O ATOM 807 CB GLN A 575 -33.287 -41.289 19.974 1.00 41.11 C ANISOU 807 CB GLN A 575 3332 6250 6039 565 532 196 C ATOM 808 CG GLN A 575 -34.436 -42.241 20.214 1.00 42.43 C ANISOU 808 CG GLN A 575 3251 6731 6138 315 557 337 C ATOM 809 CD GLN A 575 -33.996 -43.480 20.960 1.00 38.63 C ANISOU 809 CD GLN A 575 2960 6276 5443 0 565 443 C ATOM 810 OE1 GLN A 575 -33.547 -44.451 20.352 1.00 44.83 O ANISOU 810 OE1 GLN A 575 3981 6833 6217 -184 382 560 O ATOM 811 NE2 GLN A 575 -34.110 -43.454 22.279 1.00 34.90 N ANISOU 811 NE2 GLN A 575 2395 6066 4800 -80 756 393 N ATOM 812 N ASP A 576 -32.820 -38.219 19.989 1.00 41.27 N ANISOU 812 N ASP A 576 3352 5924 6406 1235 524 -146 N ATOM 813 CA ASP A 576 -32.015 -37.028 20.225 1.00 38.20 C ANISOU 813 CA ASP A 576 3164 5272 6079 1439 491 -298 C ATOM 814 C ASP A 576 -31.325 -37.095 21.587 1.00 37.33 C ANISOU 814 C ASP A 576 3214 5236 5732 1392 716 -470 C ATOM 815 O ASP A 576 -31.996 -37.128 22.622 1.00 44.56 O ANISOU 815 O ASP A 576 3944 6416 6572 1423 954 -646 O ATOM 816 CB ASP A 576 -32.906 -35.773 20.139 1.00 42.50 C ANISOU 816 CB ASP A 576 3517 5718 6911 1755 424 -410 C ATOM 817 CG ASP A 576 -32.120 -34.467 20.303 1.00 52.96 C ANISOU 817 CG ASP A 576 5135 6690 8296 1912 317 -527 C ATOM 818 OD1 ASP A 576 -30.872 -34.467 20.177 1.00 52.27 O ANISOU 818 OD1 ASP A 576 5313 6436 8110 1803 230 -498 O ATOM 819 OD2 ASP A 576 -32.766 -33.428 20.537 1.00 66.75 O ANISOU 819 OD2 ASP A 576 6830 8317 10216 2139 304 -645 O ATOM 820 N PRO A 577 -29.982 -37.088 21.596 1.00 32.92 N ANISOU 820 N PRO A 577 2979 4494 5035 1284 640 -416 N ATOM 821 CA PRO A 577 -29.228 -37.051 22.862 1.00 37.59 C ANISOU 821 CA PRO A 577 3747 5136 5398 1198 787 -531 C ATOM 822 C PRO A 577 -29.350 -35.733 23.653 1.00 37.88 C ANISOU 822 C PRO A 577 3830 5093 5470 1409 881 -832 C ATOM 823 O PRO A 577 -28.980 -35.694 24.826 1.00 58.98 O ANISOU 823 O PRO A 577 6621 7885 7904 1299 1039 -971 O ATOM 824 CB PRO A 577 -27.770 -37.260 22.422 1.00 33.28 C ANISOU 824 CB PRO A 577 3472 4401 4773 1062 625 -365 C ATOM 825 CG PRO A 577 -27.816 -37.687 21.031 1.00 31.17 C ANISOU 825 CG PRO A 577 3158 4063 4623 1036 469 -205 C ATOM 826 CD PRO A 577 -29.091 -37.161 20.430 1.00 30.06 C ANISOU 826 CD PRO A 577 2800 3932 4688 1193 419 -237 C ATOM 827 N ASER A 578 -29.828 -34.668 23.016 0.51 42.55 N ANISOU 827 N ASER A 578 4355 5455 6359 1686 749 -929 N ATOM 828 N BSER A 578 -29.879 -34.687 23.024 0.49 42.76 N ANISOU 828 N BSER A 578 4367 5492 6387 1689 757 -932 N ATOM 829 CA ASER A 578 -29.925 -33.359 23.671 0.51 45.08 C ANISOU 829 CA ASER A 578 4773 5581 6775 1913 786 -1235 C ATOM 830 CA BSER A 578 -30.122 -33.421 23.717 0.49 45.67 C ANISOU 830 CA BSER A 578 4800 5700 6852 1920 818 -1242 C ATOM 831 C ASER A 578 -30.617 -33.428 25.029 0.51 50.42 C ANISOU 831 C ASER A 578 5332 6569 7257 1905 1136 -1514 C ATOM 832 C BSER A 578 -31.521 -33.371 24.334 0.49 49.91 C ANISOU 832 C BSER A 578 5051 6490 7424 2032 1064 -1400 C ATOM 833 O ASER A 578 -31.433 -34.317 25.272 0.51 55.11 O ANISOU 833 O ASER A 578 5655 7530 7756 1799 1317 -1458 O ATOM 834 O BSER A 578 -31.895 -32.380 24.967 0.49 50.06 O ANISOU 834 O BSER A 578 5106 6405 7509 2219 1157 -1666 O ATOM 835 CB ASER A 578 -30.664 -32.373 22.773 0.51 48.45 C ANISOU 835 CB ASER A 578 5131 5729 7547 2132 561 -1160 C ATOM 836 CB BSER A 578 -29.927 -32.242 22.768 0.49 46.02 C ANISOU 836 CB BSER A 578 4998 5304 7183 2073 483 -1151 C ATOM 837 OG ASER A 578 -29.937 -32.114 21.587 0.51 47.34 O ANISOU 837 OG ASER A 578 5150 5313 7523 2065 211 -906 O ATOM 838 OG BSER A 578 -31.153 -31.863 22.172 0.49 57.96 O ANISOU 838 OG BSER A 578 6269 6792 8961 2248 410 -1087 O ATOM 839 N AGLY A 579 -30.284 -32.485 25.909 0.51 55.84 N ANISOU 839 N AGLY A 579 6239 7120 7859 1975 1214 -1810 N ATOM 840 N BGLY A 579 -32.297 -34.435 24.145 0.49 51.06 N ANISOU 840 N BGLY A 579 4904 6965 7531 1914 1161 -1244 N ATOM 841 CA AGLY A 579 -30.817 -32.461 27.260 0.51 60.80 C ANISOU 841 CA AGLY A 579 6806 8065 8229 1920 1550 -2110 C ATOM 842 CA BGLY A 579 -33.521 -34.610 24.908 0.49 44.67 C ANISOU 842 CA BGLY A 579 3797 6504 6674 1934 1431 -1380 C ATOM 843 C AGLY A 579 -30.195 -33.582 28.063 0.51 63.47 C ANISOU 843 C AGLY A 579 7193 8801 8123 1531 1714 -2052 C ATOM 844 C BGLY A 579 -33.116 -35.139 26.268 0.49 55.43 C ANISOU 844 C BGLY A 579 5249 8193 7620 1672 1699 -1543 C ATOM 845 O AGLY A 579 -29.078 -34.004 27.774 0.51 60.15 O ANISOU 845 O AGLY A 579 6990 8264 7602 1334 1533 -1809 O ATOM 846 O BGLY A 579 -31.935 -35.419 26.482 0.49 62.75 O ANISOU 846 O BGLY A 579 6437 9064 8342 1498 1649 -1510 O ATOM 847 N AASP A 580 -30.915 -34.101 29.049 0.51 68.18 N ANISOU 847 N AASP A 580 7618 9847 8442 1343 1991 -2142 N ATOM 848 N BASP A 580 -34.057 -35.321 27.186 0.49 61.69 N ANISOU 848 N BASP A 580 5817 9368 8256 1600 1970 -1691 N ATOM 849 CA AASP A 580 -30.414 -35.287 29.717 0.51 68.53 C ANISOU 849 CA AASP A 580 7693 10283 8062 880 2077 -1959 C ATOM 850 CA BASP A 580 -33.639 -35.848 28.475 0.49 70.94 C ANISOU 850 CA BASP A 580 7102 10890 8961 1254 2178 -1788 C ATOM 851 C AASP A 580 -30.999 -36.487 28.986 0.51 66.80 C ANISOU 851 C AASP A 580 7179 10253 7949 782 2018 -1622 C ATOM 852 C BASP A 580 -33.728 -37.361 28.405 0.49 72.31 C ANISOU 852 C BASP A 580 7148 11400 8928 854 2150 -1452 C ATOM 853 O AASP A 580 -32.170 -36.827 29.157 0.51 72.29 O ANISOU 853 O AASP A 580 7591 11222 8655 757 2145 -1611 O ATOM 854 O BASP A 580 -34.799 -37.959 28.509 0.49 74.48 O ANISOU 854 O BASP A 580 7127 11999 9173 726 2238 -1362 O ATOM 855 CB AASP A 580 -30.812 -35.283 31.195 0.51 72.98 C ANISOU 855 CB AASP A 580 8267 11249 8213 612 2336 -2159 C ATOM 856 CB BASP A 580 -34.511 -35.294 29.600 0.49 77.60 C ANISOU 856 CB BASP A 580 7804 12018 9663 1302 2475 -2125 C ATOM 857 CG AASP A 580 -30.423 -36.561 31.908 0.51 74.69 C ANISOU 857 CG AASP A 580 8520 11870 7991 44 2342 -1851 C ATOM 858 CG BASP A 580 -35.987 -35.348 29.266 0.49 79.28 C ANISOU 858 CG BASP A 580 7579 12426 10119 1471 2569 -2114 C ATOM 859 OD1AASP A 580 -29.455 -37.224 31.469 0.51 72.38 O ANISOU 859 OD1AASP A 580 8386 11433 7684 -139 2120 -1509 O ATOM 860 OD1BASP A 580 -36.313 -35.527 28.072 0.49 74.88 O ANISOU 860 OD1BASP A 580 6874 11678 9899 1612 2363 -1866 O ATOM 861 OD2AASP A 580 -31.088 -36.900 32.911 0.51 75.27 O ANISOU 861 OD2AASP A 580 8479 12354 7768 -232 2506 -1895 O ATOM 862 OD2BASP A 580 -36.816 -35.208 30.189 0.49 84.18 O ANISOU 862 OD2BASP A 580 7990 13412 10580 1442 2845 -2352 O ATOM 863 N ASER A 581 -30.164 -37.133 28.177 0.51 56.92 N ANISOU 863 N ASER A 581 6089 8738 6798 685 1733 -1247 N ATOM 864 N BSER A 581 -32.562 -37.962 28.224 0.49 69.94 N ANISOU 864 N BSER A 581 7076 11006 8492 648 2005 -1256 N ATOM 865 CA ASER A 581 -30.618 -38.213 27.312 0.51 48.46 C ANISOU 865 CA ASER A 581 4834 7705 5872 607 1603 -927 C ATOM 866 CA BSER A 581 -32.433 -39.395 28.051 0.49 63.49 C ANISOU 866 CA BSER A 581 6220 10379 7526 269 1892 -878 C ATOM 867 C ASER A 581 -30.664 -39.582 27.966 0.51 56.98 C ANISOU 867 C ASER A 581 5895 9092 6664 151 1600 -648 C ATOM 868 C BSER A 581 -31.238 -39.965 28.806 0.49 63.98 C ANISOU 868 C BSER A 581 6643 10375 7292 -100 1766 -668 C ATOM 869 O ASER A 581 -31.641 -40.314 27.801 0.51 59.73 O ANISOU 869 O ASER A 581 5978 9703 7015 28 1643 -534 O ATOM 870 O BSER A 581 -31.397 -40.816 29.684 0.49 74.57 O ANISOU 870 O BSER A 581 7963 12067 8304 -539 1803 -495 O ATOM 871 CB ASER A 581 -29.734 -38.296 26.073 0.51 43.35 C ANISOU 871 CB ASER A 581 4380 6618 5473 713 1297 -695 C ATOM 872 CB BSER A 581 -32.355 -39.737 26.569 0.49 58.16 C ANISOU 872 CB BSER A 581 5559 9332 7205 427 1605 -631 C ATOM 873 OG ASER A 581 -28.353 -38.268 26.404 0.51 39.71 O ANISOU 873 OG ASER A 581 4238 5968 4883 578 1171 -594 O ATOM 874 OG BSER A 581 -33.643 -39.659 25.983 0.49 52.42 O ANISOU 874 OG BSER A 581 4441 8791 6685 586 1666 -673 O ATOM 875 N ALYS A 582 -29.599 -39.910 28.701 0.51 54.52 N ANISOU 875 N ALYS A 582 5865 8731 6119 -128 1501 -499 N ATOM 876 N BLYS A 582 -30.053 -39.455 28.456 0.49 58.05 N ANISOU 876 N BLYS A 582 6201 9192 6665 55 1587 -654 N ATOM 877 CA ALYS A 582 -29.311 -41.279 29.127 0.51 53.63 C ANISOU 877 CA ALYS A 582 5820 8717 5839 -560 1330 -118 C ATOM 878 CA BLYS A 582 -28.769 -40.155 28.564 0.49 52.13 C ANISOU 878 CA BLYS A 582 5742 8217 5846 -185 1329 -336 C ATOM 879 C ALYS A 582 -29.139 -42.175 27.888 0.51 52.96 C ANISOU 879 C ALYS A 582 5743 8298 6082 -474 1065 145 C ATOM 880 C BLYS A 582 -28.752 -41.362 27.629 0.49 51.14 C ANISOU 880 C BLYS A 582 5578 7915 5936 -244 1097 -14 C ATOM 881 O ALYS A 582 -29.337 -43.386 27.950 0.51 60.11 O ANISOU 881 O ALYS A 582 6635 9243 6963 -763 909 427 O ATOM 882 O BLYS A 582 -28.812 -42.508 28.068 0.49 55.95 O ANISOU 882 O BLYS A 582 6195 8637 6427 -585 985 253 O ATOM 883 CB ALYS A 582 -30.414 -41.807 30.056 0.51 65.27 C ANISOU 883 CB ALYS A 582 7064 10752 6982 -924 1527 -106 C ATOM 884 CB BLYS A 582 -28.471 -40.594 30.001 0.49 55.19 C ANISOU 884 CB BLYS A 582 6242 8912 5814 -641 1369 -233 C ATOM 885 CG ALYS A 582 -30.052 -43.009 30.918 0.51 60.80 C ANISOU 885 CG ALYS A 582 6631 10339 6132 -1495 1325 297 C ATOM 886 CG BLYS A 582 -28.281 -39.455 30.981 0.49 62.37 C ANISOU 886 CG BLYS A 582 7276 9977 6446 -652 1582 -578 C ATOM 887 CD ALYS A 582 -31.253 -43.442 31.752 0.51 62.98 C ANISOU 887 CD ALYS A 582 6660 11211 6060 -1883 1507 306 C ATOM 888 CD BLYS A 582 -28.334 -39.966 32.412 0.49 66.10 C ANISOU 888 CD BLYS A 582 7798 10910 6408 -1201 1668 -488 C ATOM 889 CE ALYS A 582 -31.042 -44.804 32.397 0.51 66.02 C ANISOU 889 CE ALYS A 582 7198 11619 6269 -2444 1150 785 C ATOM 890 CE BLYS A 582 -28.388 -38.819 33.409 0.49 68.11 C ANISOU 890 CE BLYS A 582 8154 11404 6319 -1232 1960 -946 C ATOM 891 NZ ALYS A 582 -32.269 -45.282 33.112 0.51 74.38 N ANISOU 891 NZ ALYS A 582 8060 13134 7067 -2754 1195 784 N ATOM 892 NZ BLYS A 582 -28.630 -39.313 34.790 0.49 72.73 N ANISOU 892 NZ BLYS A 582 8765 12395 6472 -1754 1977 -854 N ATOM 893 N ALEU A 583 -28.742 -41.569 26.768 0.51 46.23 N ANISOU 893 N ALEU A 583 4937 7112 5515 -115 997 44 N ATOM 894 N BLEU A 583 -28.697 -41.077 26.329 0.49 44.48 N ANISOU 894 N BLEU A 583 4714 6788 5400 62 1005 -49 N ATOM 895 CA ALEU A 583 -28.564 -42.290 25.503 0.51 38.53 C ANISOU 895 CA ALEU A 583 3978 5857 4804 -30 794 200 C ATOM 896 CA BLEU A 583 -28.548 -42.101 25.293 0.49 37.49 C ANISOU 896 CA BLEU A 583 3844 5688 4713 38 798 165 C ATOM 897 C ALEU A 583 -27.084 -42.507 25.146 0.51 37.43 C ANISOU 897 C ALEU A 583 4060 5381 4779 18 600 306 C ATOM 898 C BLEU A 583 -27.077 -42.426 25.049 0.49 37.23 C ANISOU 898 C BLEU A 583 4034 5343 4768 46 603 290 C ATOM 899 O ALEU A 583 -26.754 -43.365 24.324 0.51 31.53 O ANISOU 899 O ALEU A 583 3348 4421 4210 32 441 414 O ATOM 900 O BLEU A 583 -26.741 -43.292 24.237 0.49 30.36 O ANISOU 900 O BLEU A 583 3198 4264 4072 55 445 399 O ATOM 901 CB ALEU A 583 -29.254 -41.538 24.358 0.51 36.96 C ANISOU 901 CB ALEU A 583 3631 5599 4813 268 839 42 C ATOM 902 CB BLEU A 583 -29.187 -41.638 23.982 0.49 31.54 C ANISOU 902 CB BLEU A 583 2956 4841 4186 295 790 66 C ATOM 903 CG ALEU A 583 -30.779 -41.374 24.441 0.51 47.31 C ANISOU 903 CG ALEU A 583 4623 7227 6123 289 998 -48 C ATOM 904 CG BLEU A 583 -30.710 -41.496 24.002 0.49 43.95 C ANISOU 904 CG BLEU A 583 4219 6712 5768 313 930 -6 C ATOM 905 CD1ALEU A 583 -31.298 -40.432 23.353 0.51 44.60 C ANISOU 905 CD1ALEU A 583 4143 6760 6043 611 967 -169 C ATOM 906 CD1BLEU A 583 -31.217 -40.627 22.850 0.49 42.64 C ANISOU 906 CD1BLEU A 583 3924 6424 5854 606 882 -103 C ATOM 907 CD2ALEU A 583 -31.483 -42.726 24.364 0.51 43.58 C ANISOU 907 CD2ALEU A 583 4044 6915 5599 -17 916 188 C ATOM 908 CD2BLEU A 583 -31.365 -42.872 23.986 0.49 40.56 C ANISOU 908 CD2BLEU A 583 3701 6432 5278 1 849 223 C ATOM 909 N TYR A 584 -26.193 -41.720 25.743 1.00 31.20 N ANISOU 909 N TYR A 584 3405 4560 3890 45 617 248 N ATOM 910 CA TYR A 584 -24.773 -41.893 25.496 1.00 32.03 C ANISOU 910 CA TYR A 584 3647 4426 4099 74 441 368 C ATOM 911 C TYR A 584 -24.002 -41.776 26.780 1.00 32.30 C ANISOU 911 C TYR A 584 3807 4535 3929 -147 387 481 C ATOM 912 O TYR A 584 -24.467 -41.186 27.754 1.00 34.88 O ANISOU 912 O TYR A 584 4169 5092 3993 -284 532 373 O ATOM 913 CB TYR A 584 -24.258 -40.884 24.459 1.00 28.54 C ANISOU 913 CB TYR A 584 3232 3836 3776 327 444 229 C ATOM 914 CG TYR A 584 -24.044 -39.469 24.963 1.00 26.68 C ANISOU 914 CG TYR A 584 3103 3625 3409 378 511 81 C ATOM 915 CD1 TYR A 584 -25.078 -38.543 24.950 1.00 24.96 C ANISOU 915 CD1 TYR A 584 2833 3463 3187 521 645 -140 C ATOM 916 CD2 TYR A 584 -22.795 -39.049 25.417 1.00 24.81 C ANISOU 916 CD2 TYR A 584 3014 3325 3087 291 410 159 C ATOM 917 CE1 TYR A 584 -24.882 -37.233 25.398 1.00 31.99 C ANISOU 917 CE1 TYR A 584 3862 4287 4006 596 674 -324 C ATOM 918 CE2 TYR A 584 -22.592 -37.748 25.868 1.00 30.92 C ANISOU 918 CE2 TYR A 584 3943 4073 3733 300 433 14 C ATOM 919 CZ TYR A 584 -23.639 -36.845 25.850 1.00 38.68 C ANISOU 919 CZ TYR A 584 4917 5051 4730 463 562 -247 C ATOM 920 OH TYR A 584 -23.448 -35.559 26.295 1.00 36.37 O ANISOU 920 OH TYR A 584 4813 4649 4355 498 556 -436 O ATOM 921 N ARG A 585 -22.827 -42.387 26.786 1.00 35.83 N ANISOU 921 N ARG A 585 4305 4806 4502 -195 174 691 N ATOM 922 CA ARG A 585 -21.926 -42.258 27.900 1.00 26.93 C ANISOU 922 CA ARG A 585 3291 3729 3211 -426 51 863 C ATOM 923 C ARG A 585 -20.697 -41.549 27.394 1.00 33.57 C ANISOU 923 C ARG A 585 4159 4436 4160 -263 -20 846 C ATOM 924 O ARG A 585 -20.151 -41.927 26.341 1.00 29.38 O ANISOU 924 O ARG A 585 3518 3741 3902 -51 -84 850 O ATOM 925 CB ARG A 585 -21.548 -43.628 28.486 1.00 32.12 C ANISOU 925 CB ARG A 585 3940 4300 3963 -666 -222 1211 C ATOM 926 CG ARG A 585 -20.502 -43.525 29.590 1.00 45.12 C ANISOU 926 CG ARG A 585 5686 5991 5467 -939 -426 1465 C ATOM 927 CD ARG A 585 -20.312 -44.829 30.294 1.00 57.59 C ANISOU 927 CD ARG A 585 7266 7482 7132 -1235 -754 1861 C ATOM 928 NE ARG A 585 -21.599 -45.462 30.541 1.00 75.42 N ANISOU 928 NE ARG A 585 9525 9886 9245 -1449 -691 1882 N ATOM 929 CZ ARG A 585 -21.748 -46.734 30.881 1.00 80.29 C ANISOU 929 CZ ARG A 585 10151 10373 9984 -1703 -997 2220 C ATOM 930 NH1 ARG A 585 -20.679 -47.512 31.010 1.00 85.72 N ANISOU 930 NH1 ARG A 585 10838 10726 11005 -1711 -1399 2542 N ATOM 931 NH2 ARG A 585 -22.965 -47.224 31.086 1.00 75.50 N ANISOU 931 NH2 ARG A 585 9533 9961 9192 -1954 -931 2251 N ATOM 932 N LEU A 586 -20.278 -40.524 28.134 1.00 30.69 N ANISOU 932 N LEU A 586 3939 4170 3552 -396 -1 806 N ATOM 933 CA LEU A 586 -18.984 -39.894 27.948 1.00 29.16 C ANISOU 933 CA LEU A 586 3784 3901 3394 -378 -131 886 C ATOM 934 C LEU A 586 -18.000 -40.527 28.930 1.00 35.30 C ANISOU 934 C LEU A 586 4568 4705 4137 -654 -383 1227 C ATOM 935 O LEU A 586 -18.125 -40.347 30.140 1.00 31.35 O ANISOU 935 O LEU A 586 4227 4357 3327 -981 -414 1301 O ATOM 936 CB LEU A 586 -19.067 -38.380 28.180 1.00 31.28 C ANISOU 936 CB LEU A 586 4251 4204 3431 -401 -34 667 C ATOM 937 CG LEU A 586 -17.709 -37.678 28.097 1.00 38.17 C ANISOU 937 CG LEU A 586 5191 5029 4282 -487 -213 802 C ATOM 938 CD1 LEU A 586 -16.999 -38.060 26.802 1.00 24.74 C ANISOU 938 CD1 LEU A 586 3261 3265 2876 -279 -277 895 C ATOM 939 CD2 LEU A 586 -17.837 -36.137 28.221 1.00 42.39 C ANISOU 939 CD2 LEU A 586 5981 5501 4625 -514 -173 573 C ATOM 940 N HIS A 587 -17.039 -41.289 28.416 1.00 30.43 N ANISOU 940 N HIS A 587 3935 4005 3623 433 -183 1346 N ATOM 941 CA HIS A 587 -16.021 -41.906 29.272 1.00 26.51 C ANISOU 941 CA HIS A 587 3467 3512 3094 552 -267 1188 C ATOM 942 C HIS A 587 -15.009 -40.841 29.708 1.00 26.49 C ANISOU 942 C HIS A 587 3484 3462 3117 596 -364 970 C ATOM 943 O HIS A 587 -14.782 -39.878 28.991 1.00 27.26 O ANISOU 943 O HIS A 587 3556 3500 3301 484 -358 894 O ATOM 944 CB HIS A 587 -15.303 -43.043 28.530 1.00 29.70 C ANISOU 944 CB HIS A 587 3817 3886 3581 412 -249 1159 C ATOM 945 CG HIS A 587 -16.186 -44.215 28.220 1.00 33.59 C ANISOU 945 CG HIS A 587 4333 4417 4011 345 -149 1349 C ATOM 946 ND1 HIS A 587 -16.565 -45.139 29.173 1.00 30.51 N ANISOU 946 ND1 HIS A 587 3982 4089 3521 513 -140 1439 N ATOM 947 CD2 HIS A 587 -16.787 -44.597 27.069 1.00 25.47 C ANISOU 947 CD2 HIS A 587 3312 3379 2986 100 -58 1474 C ATOM 948 CE1 HIS A 587 -17.357 -46.040 28.621 1.00 31.10 C ANISOU 948 CE1 HIS A 587 4083 4181 3551 381 -41 1586 C ATOM 949 NE2 HIS A 587 -17.509 -45.731 27.344 1.00 31.96 N ANISOU 949 NE2 HIS A 587 4181 4251 3712 116 6 1603 N ATOM 950 N PRO A 588 -14.415 -41.005 30.891 1.00 31.62 N ANISOU 950 N PRO A 588 4188 4149 3680 736 -463 882 N ATOM 951 CA PRO A 588 -13.246 -40.196 31.252 1.00 33.26 C ANISOU 951 CA PRO A 588 4406 4331 3901 714 -590 682 C ATOM 952 C PRO A 588 -12.191 -40.230 30.153 1.00 39.26 C ANISOU 952 C PRO A 588 5030 5035 4851 551 -624 586 C ATOM 953 O PRO A 588 -12.076 -41.255 29.484 1.00 39.43 O ANISOU 953 O PRO A 588 4968 5043 4971 490 -564 658 O ATOM 954 CB PRO A 588 -12.701 -40.876 32.520 1.00 30.47 C ANISOU 954 CB PRO A 588 4082 4060 3435 833 -717 676 C ATOM 955 CG PRO A 588 -13.713 -41.960 32.892 1.00 27.00 C ANISOU 955 CG PRO A 588 3671 3675 2914 951 -630 859 C ATOM 956 CD PRO A 588 -14.895 -41.855 31.997 1.00 28.69 C ANISOU 956 CD PRO A 588 3881 3853 3167 902 -468 984 C ATOM 957 N CYS A 589 -11.455 -39.137 29.960 1.00 36.10 N ANISOU 957 N CYS A 589 4629 4588 4501 471 -692 426 N ATOM 958 CA CYS A 589 -10.316 -39.142 29.046 1.00 33.14 C ANISOU 958 CA CYS A 589 4123 4156 4314 329 -728 326 C ATOM 959 C CYS A 589 -9.149 -39.907 29.672 1.00 31.98 C ANISOU 959 C CYS A 589 3874 4055 4222 379 -855 318 C ATOM 960 O CYS A 589 -8.652 -39.544 30.736 1.00 38.69 O ANISOU 960 O CYS A 589 4758 4975 4965 433 -1011 271 O ATOM 961 CB CYS A 589 -9.887 -37.715 28.701 1.00 32.24 C ANISOU 961 CB CYS A 589 4035 3981 4234 231 -768 166 C ATOM 962 SG CYS A 589 -8.523 -37.633 27.514 1.00 37.39 S ANISOU 962 SG CYS A 589 4528 4550 5129 52 -794 44 S ATOM 963 N ARG A 590 -8.726 -40.985 29.029 1.00 34.47 N ANISOU 963 N ARG A 590 4069 4327 4701 346 -774 386 N ATOM 964 CA ARG A 590 -7.621 -41.770 29.569 1.00 35.68 C ANISOU 964 CA ARG A 590 4082 4511 4963 412 -861 436 C ATOM 965 C ARG A 590 -6.421 -41.763 28.652 1.00 28.89 C ANISOU 965 C ARG A 590 3065 3547 4365 299 -824 378 C ATOM 966 O ARG A 590 -5.349 -42.221 29.051 1.00 33.30 O ANISOU 966 O ARG A 590 3461 4125 5065 347 -902 442 O ATOM 967 CB ARG A 590 -8.053 -43.219 29.817 1.00 30.89 C ANISOU 967 CB ARG A 590 3461 3918 4358 519 -752 605 C ATOM 968 CG ARG A 590 -8.338 -44.000 28.534 1.00 34.05 C ANISOU 968 CG ARG A 590 3862 4185 4891 407 -506 641 C ATOM 969 CD ARG A 590 -8.944 -45.385 28.821 1.00 39.15 C ANISOU 969 CD ARG A 590 4543 4838 5494 498 -378 800 C ATOM 970 NE ARG A 590 -9.325 -46.061 27.581 1.00 30.61 N ANISOU 970 NE ARG A 590 3526 3623 4482 332 -130 822 N ATOM 971 CZ ARG A 590 -9.944 -47.235 27.521 1.00 27.23 C ANISOU 971 CZ ARG A 590 3172 3168 4008 338 32 942 C ATOM 972 NH1 ARG A 590 -10.262 -47.876 28.635 1.00 26.35 N ANISOU 972 NH1 ARG A 590 3054 3157 3802 533 -30 1056 N ATOM 973 NH2 ARG A 590 -10.241 -47.767 26.341 1.00 29.17 N ANISOU 973 NH2 ARG A 590 3516 3283 4284 124 260 945 N ATOM 974 N SER A 591 -6.576 -41.283 27.418 1.00 27.54 N ANISOU 974 N SER A 591 2926 3264 4273 144 -697 284 N ATOM 975 CA SER A 591 -5.466 -41.449 26.474 1.00 40.37 C ANISOU 975 CA SER A 591 4417 4760 6161 35 -607 237 C ATOM 976 C SER A 591 -4.472 -40.306 26.580 1.00 38.25 C ANISOU 976 C SER A 591 4065 4510 5959 -19 -781 111 C ATOM 977 O SER A 591 -3.403 -40.351 25.972 1.00 41.01 O ANISOU 977 O SER A 591 4272 4766 6543 -88 -737 83 O ATOM 978 CB SER A 591 -5.961 -41.574 25.034 1.00 41.46 C ANISOU 978 CB SER A 591 4642 4758 6354 -150 -380 198 C ATOM 979 OG SER A 591 -6.381 -40.327 24.521 1.00 37.16 O ANISOU 979 OG SER A 591 4174 4216 5729 -270 -432 84 O ATOM 980 N LEU A 592 -4.829 -39.283 27.352 1.00 42.30 N ANISOU 980 N LEU A 592 4679 5127 6266 5 -954 37 N ATOM 981 CA LEU A 592 -3.862 -38.258 27.762 1.00 49.70 C ANISOU 981 CA LEU A 592 5564 6110 7210 -53 -1153 -70 C ATOM 982 C LEU A 592 -4.290 -37.586 29.058 1.00 43.81 C ANISOU 982 C LEU A 592 4973 5491 6182 1 -1325 -99 C ATOM 983 O LEU A 592 -5.327 -37.916 29.635 1.00 47.22 O ANISOU 983 O LEU A 592 5538 5969 6436 105 -1279 -33 O ATOM 984 CB LEU A 592 -3.658 -37.215 26.659 1.00 46.85 C ANISOU 984 CB LEU A 592 5222 5640 6940 -210 -1094 -234 C ATOM 985 CG LEU A 592 -4.924 -36.777 25.931 1.00 46.09 C ANISOU 985 CG LEU A 592 5285 5485 6745 -260 -943 -271 C ATOM 986 CD1 LEU A 592 -5.527 -35.626 26.646 1.00 48.26 C ANISOU 986 CD1 LEU A 592 5718 5811 6806 -230 -1026 -346 C ATOM 987 CD2 LEU A 592 -4.603 -36.420 24.496 1.00 45.89 C ANISOU 987 CD2 LEU A 592 5216 5325 6894 -433 -821 -358 C ATOM 988 N GLN A 593 -3.472 -36.653 29.519 1.00 44.33 N ANISOU 988 N GLN A 593 5039 5605 6200 -90 -1509 -198 N ATOM 989 CA GLN A 593 -3.694 -36.029 30.811 1.00 52.13 C ANISOU 989 CA GLN A 593 6210 6697 6898 -92 -1666 -237 C ATOM 990 C GLN A 593 -4.439 -34.714 30.681 1.00 44.05 C ANISOU 990 C GLN A 593 5425 5596 5717 -147 -1577 -409 C ATOM 991 O GLN A 593 -3.860 -33.716 30.280 1.00 45.65 O ANISOU 991 O GLN A 593 5638 5746 5960 -280 -1616 -552 O ATOM 992 CB GLN A 593 -2.360 -35.803 31.527 1.00 51.45 C ANISOU 992 CB GLN A 593 6015 6727 6809 -204 -1934 -218 C ATOM 993 CG GLN A 593 -1.521 -37.059 31.611 1.00 71.54 C ANISOU 993 CG GLN A 593 8270 9338 9575 -139 -2006 2 C ATOM 994 CD GLN A 593 -0.953 -37.285 32.996 1.00 91.50 C ANISOU 994 CD GLN A 593 10768 12056 11942 -173 -2282 144 C ATOM 995 OE1 GLN A 593 -0.259 -36.424 33.544 1.00 97.03 O ANISOU 995 OE1 GLN A 593 11511 12844 12511 -351 -2504 86 O ATOM 996 NE2 GLN A 593 -1.256 -38.445 33.578 1.00 93.05 N ANISOU 996 NE2 GLN A 593 10902 12323 12130 -28 -2277 339 N ATOM 997 N ILE A 594 -5.728 -34.731 30.995 1.00 39.94 N ANISOU 997 N ILE A 594 5083 5053 5040 -37 -1435 -376 N ATOM 998 CA ILE A 594 -6.501 -33.498 31.104 1.00 40.07 C ANISOU 998 CA ILE A 594 5335 4983 4908 -56 -1316 -493 C ATOM 999 C ILE A 594 -7.272 -33.485 32.411 1.00 45.13 C ANISOU 999 C ILE A 594 6211 5663 5273 35 -1293 -461 C ATOM 1000 O ILE A 594 -7.470 -34.534 33.022 1.00 50.74 O ANISOU 1000 O ILE A 594 6887 6468 5925 135 -1343 -328 O ATOM 1001 CB ILE A 594 -7.502 -33.314 29.952 1.00 38.68 C ANISOU 1001 CB ILE A 594 5137 4698 4863 -18 -1090 -452 C ATOM 1002 CG1 ILE A 594 -8.490 -34.468 29.890 1.00 36.72 C ANISOU 1002 CG1 ILE A 594 4843 4485 4621 115 -985 -259 C ATOM 1003 CG2 ILE A 594 -6.798 -33.184 28.639 1.00 39.38 C ANISOU 1003 CG2 ILE A 594 5047 4726 5189 -143 -1089 -508 C ATOM 1004 CD1 ILE A 594 -9.575 -34.244 28.833 1.00 28.02 C ANISOU 1004 CD1 ILE A 594 3728 3306 3615 111 -788 -169 C ATOM 1005 N ARG A 595 -7.704 -32.300 32.834 1.00 48.08 N ANISOU 1005 N ARG A 595 6840 5944 5482 -1 -1189 -583 N ATOM 1006 CA ARG A 595 -8.542 -32.174 34.017 1.00 50.79 C ANISOU 1006 CA ARG A 595 7457 6275 5567 80 -1092 -565 C ATOM 1007 C ARG A 595 -9.718 -33.154 33.967 1.00 56.19 C ANISOU 1007 C ARG A 595 8081 6976 6291 283 -949 -367 C ATOM 1008 O ARG A 595 -10.366 -33.302 32.932 1.00 57.72 O ANISOU 1008 O ARG A 595 8136 7118 6676 346 -808 -271 O ATOM 1009 CB ARG A 595 -9.059 -30.752 34.155 1.00 64.50 C ANISOU 1009 CB ARG A 595 9468 7840 7199 44 -877 -700 C ATOM 1010 CG ARG A 595 -10.330 -30.692 34.969 1.00 75.05 C ANISOU 1010 CG ARG A 595 11046 9095 8374 196 -636 -625 C ATOM 1011 CD ARG A 595 -11.299 -29.720 34.375 1.00 63.88 C ANISOU 1011 CD ARG A 595 9707 7487 7076 279 -316 -604 C ATOM 1012 NE ARG A 595 -10.762 -28.379 34.482 1.00 50.91 N ANISOU 1012 NE ARG A 595 8277 5711 5354 125 -253 -816 N ATOM 1013 CZ ARG A 595 -11.161 -27.361 33.733 1.00 50.03 C ANISOU 1013 CZ ARG A 595 8180 5432 5398 141 -26 -833 C ATOM 1014 NH1 ARG A 595 -12.106 -27.535 32.815 1.00 37.79 N ANISOU 1014 NH1 ARG A 595 6424 3848 4089 291 134 -624 N ATOM 1015 NH2 ARG A 595 -10.618 -26.166 33.906 1.00 50.49 N ANISOU 1015 NH2 ARG A 595 8460 5361 5364 -11 37 -1041 N ATOM 1016 N GLN A 596 -9.971 -33.836 35.081 1.00 47.50 N ANISOU 1016 N GLN A 596 7088 5960 5001 356 -1000 -294 N ATOM 1017 CA GLN A 596 -10.986 -34.872 35.133 1.00 46.09 C ANISOU 1017 CA GLN A 596 6849 5818 4848 537 -894 -102 C ATOM 1018 C GLN A 596 -12.221 -34.405 35.892 1.00 59.45 C ANISOU 1018 C GLN A 596 8806 7414 6369 656 -657 -69 C ATOM 1019 O GLN A 596 -12.123 -34.021 37.057 1.00 73.03 O ANISOU 1019 O GLN A 596 10790 9120 7836 615 -667 -159 O ATOM 1020 CB GLN A 596 -10.414 -36.126 35.794 1.00 56.78 C ANISOU 1020 CB GLN A 596 8097 7331 6145 560 -1103 -9 C ATOM 1021 CG GLN A 596 -9.128 -36.637 35.154 1.00 63.98 C ANISOU 1021 CG GLN A 596 8735 8318 7255 463 -1304 -7 C ATOM 1022 CD GLN A 596 -9.396 -37.547 33.968 1.00 68.57 C ANISOU 1022 CD GLN A 596 9083 8878 8093 531 -1202 113 C ATOM 1023 OE1 GLN A 596 -10.326 -38.357 33.999 1.00 76.82 O ANISOU 1023 OE1 GLN A 596 10128 9936 9126 658 -1088 252 O ATOM 1024 NE2 GLN A 596 -8.585 -37.419 32.915 1.00 61.71 N ANISOU 1024 NE2 GLN A 596 8035 7968 7444 426 -1233 59 N ATOM 1025 N TYR A 597 -13.378 -34.419 35.235 1.00 56.95 N ANISOU 1025 N TYR A 597 8425 7024 6189 782 -433 78 N ATOM 1026 CA TYR A 597 -14.629 -34.128 35.931 1.00 52.59 C ANISOU 1026 CA TYR A 597 8078 6377 5529 930 -176 172 C ATOM 1027 C TYR A 597 -15.062 -35.357 36.708 1.00 56.13 C ANISOU 1027 C TYR A 597 8529 6938 5860 1049 -226 306 C ATOM 1028 O TYR A 597 -15.193 -36.433 36.133 1.00 54.73 O ANISOU 1028 O TYR A 597 8124 6865 5806 1091 -303 449 O ATOM 1029 CB TYR A 597 -15.735 -33.726 34.964 1.00 43.40 C ANISOU 1029 CB TYR A 597 6798 5113 4578 1018 67 347 C ATOM 1030 CG TYR A 597 -15.628 -32.329 34.440 1.00 52.62 C ANISOU 1030 CG TYR A 597 8028 6125 5841 948 208 248 C ATOM 1031 CD1 TYR A 597 -15.746 -31.235 35.289 1.00 52.49 C ANISOU 1031 CD1 TYR A 597 8323 5941 5679 957 405 118 C ATOM 1032 CD2 TYR A 597 -15.433 -32.095 33.086 1.00 54.61 C ANISOU 1032 CD2 TYR A 597 8049 6379 6320 859 170 285 C ATOM 1033 CE1 TYR A 597 -15.649 -29.941 34.801 1.00 52.88 C ANISOU 1033 CE1 TYR A 597 8439 5826 5826 897 565 29 C ATOM 1034 CE2 TYR A 597 -15.338 -30.810 32.592 1.00 56.63 C ANISOU 1034 CE2 TYR A 597 8353 6491 6674 799 301 205 C ATOM 1035 CZ TYR A 597 -15.451 -29.741 33.451 1.00 52.34 C ANISOU 1035 CZ TYR A 597 8106 5779 6001 829 502 81 C ATOM 1036 OH TYR A 597 -15.366 -28.473 32.944 1.00 49.60 O ANISOU 1036 OH TYR A 597 7810 5271 5762 775 660 8 O ATOM 1037 N ALA A 598 -15.293 -35.193 38.006 1.00 59.00 N ANISOU 1037 N ALA A 598 9175 7270 5973 1086 -163 255 N ATOM 1038 CA ALA A 598 -15.688 -36.309 38.862 1.00 59.57 C ANISOU 1038 CA ALA A 598 9279 7447 5907 1194 -211 374 C ATOM 1039 C ALA A 598 -16.963 -37.011 38.380 1.00 57.98 C ANISOU 1039 C ALA A 598 8926 7249 5855 1377 -37 623 C ATOM 1040 O ALA A 598 -17.084 -38.230 38.500 1.00 57.22 O ANISOU 1040 O ALA A 598 8708 7280 5754 1442 -141 746 O ATOM 1041 CB ALA A 598 -15.868 -35.831 40.299 1.00 55.04 C ANISOU 1041 CB ALA A 598 9088 6800 5025 1181 -114 274 C ATOM 1042 N TYR A 599 -17.903 -36.254 37.821 1.00 52.92 N ANISOU 1042 N TYR A 599 8279 6473 5354 1449 225 723 N ATOM 1043 CA TYR A 599 -19.203 -36.825 37.471 1.00 52.38 C ANISOU 1043 CA TYR A 599 8076 6416 5410 1600 392 1003 C ATOM 1044 C TYR A 599 -19.094 -37.899 36.383 1.00 61.57 C ANISOU 1044 C TYR A 599 8933 7727 6733 1542 223 1134 C ATOM 1045 O TYR A 599 -19.992 -38.726 36.232 1.00 63.92 O ANISOU 1045 O TYR A 599 9127 8088 7072 1625 282 1358 O ATOM 1046 CB TYR A 599 -20.181 -35.722 37.034 1.00 41.57 C ANISOU 1046 CB TYR A 599 6719 4875 4198 1675 703 1136 C ATOM 1047 CG TYR A 599 -20.072 -35.300 35.589 1.00 51.16 C ANISOU 1047 CG TYR A 599 7688 6092 5658 1567 672 1202 C ATOM 1048 CD1 TYR A 599 -20.830 -35.929 34.602 1.00 53.62 C ANISOU 1048 CD1 TYR A 599 7734 6496 6145 1563 669 1480 C ATOM 1049 CD2 TYR A 599 -19.233 -34.255 35.207 1.00 54.69 C ANISOU 1049 CD2 TYR A 599 8185 6450 6145 1443 645 995 C ATOM 1050 CE1 TYR A 599 -20.739 -35.541 33.273 1.00 52.27 C ANISOU 1050 CE1 TYR A 599 7358 6332 6171 1424 631 1551 C ATOM 1051 CE2 TYR A 599 -19.140 -33.854 33.879 1.00 50.67 C ANISOU 1051 CE2 TYR A 599 7459 5940 5854 1336 619 1059 C ATOM 1052 CZ TYR A 599 -19.892 -34.502 32.917 1.00 49.22 C ANISOU 1052 CZ TYR A 599 7020 5852 5830 1321 609 1337 C ATOM 1053 OH TYR A 599 -19.797 -34.121 31.594 1.00 47.70 O ANISOU 1053 OH TYR A 599 6632 5666 5827 1175 571 1409 O ATOM 1054 N LEU A 600 -17.990 -37.890 35.639 1.00 65.72 N ANISOU 1054 N LEU A 600 9335 8295 7340 1385 32 993 N ATOM 1055 CA LEU A 600 -17.794 -38.830 34.537 1.00 62.82 C ANISOU 1055 CA LEU A 600 8723 8023 7121 1293 -80 1086 C ATOM 1056 C LEU A 600 -17.456 -40.255 35.004 1.00 68.10 C ANISOU 1056 C LEU A 600 9350 8814 7712 1330 -218 1116 C ATOM 1057 O LEU A 600 -17.637 -41.219 34.251 1.00 59.88 O ANISOU 1057 O LEU A 600 8158 7830 6764 1282 -232 1240 O ATOM 1058 CB LEU A 600 -16.702 -38.316 33.601 1.00 56.08 C ANISOU 1058 CB LEU A 600 7768 7144 6396 1119 -196 922 C ATOM 1059 CG LEU A 600 -17.079 -37.106 32.741 1.00 50.70 C ANISOU 1059 CG LEU A 600 7057 6356 5850 1054 -64 942 C ATOM 1060 CD1 LEU A 600 -15.900 -36.670 31.890 1.00 42.83 C ANISOU 1060 CD1 LEU A 600 5973 5338 4964 879 -193 759 C ATOM 1061 CD2 LEU A 600 -18.311 -37.393 31.867 1.00 42.42 C ANISOU 1061 CD2 LEU A 600 5864 5329 4924 1049 65 1231 C ATOM 1062 N SER A 601 -16.969 -40.387 36.235 1.00 75.93 N ANISOU 1062 N SER A 601 10487 9838 8525 1392 -311 1014 N ATOM 1063 CA SER A 601 -16.741 -41.708 36.821 1.00 86.16 C ANISOU 1063 CA SER A 601 11745 11246 9746 1453 -424 1080 C ATOM 1064 C SER A 601 -17.510 -41.876 38.131 1.00 99.01 C ANISOU 1064 C SER A 601 13570 12886 11162 1602 -349 1143 C ATOM 1065 O SER A 601 -17.161 -42.717 38.958 1.00 99.23 O ANISOU 1065 O SER A 601 13622 13004 11077 1641 -468 1154 O ATOM 1066 CB SER A 601 -15.250 -41.947 37.061 1.00 79.13 C ANISOU 1066 CB SER A 601 10793 10417 8856 1363 -656 947 C ATOM 1067 OG SER A 601 -14.684 -40.898 37.823 1.00 79.71 O ANISOU 1067 OG SER A 601 11039 10465 8783 1301 -733 782 O ATOM 1068 N ASP A 602 -18.558 -41.069 38.298 1.00114.14 N ANISOU 1068 N ASP A 602 15617 14702 13049 1679 -132 1197 N ATOM 1069 CA ASP A 602 -19.367 -41.042 39.517 1.00125.47 C ANISOU 1069 CA ASP A 602 17277 16103 14294 1820 7 1248 C ATOM 1070 C ASP A 602 -18.523 -40.772 40.759 1.00129.96 C ANISOU 1070 C ASP A 602 18082 16683 14613 1764 -121 1059 C ATOM 1071 O ASP A 602 -18.694 -39.751 41.426 1.00130.41 O ANISOU 1071 O ASP A 602 18404 16616 14529 1751 19 949 O ATOM 1072 CB ASP A 602 -20.138 -42.353 39.683 1.00131.07 C ANISOU 1072 CB ASP A 602 17790 16885 15126 1793 41 1322 C ATOM 1073 CG ASP A 602 -21.202 -42.536 38.625 1.00133.00 C ANISOU 1073 CG ASP A 602 17798 17112 15624 1710 181 1427 C ATOM 1074 OD1 ASP A 602 -21.522 -41.549 37.933 1.00133.11 O ANISOU 1074 OD1 ASP A 602 17797 17052 15727 1710 291 1483 O ATOM 1075 OD2 ASP A 602 -21.723 -43.663 38.488 1.00135.20 O ANISOU 1075 OD2 ASP A 602 17920 17449 16000 1628 172 1456 O TER 1076 ASP A 602 ATOM 1077 O5' DT D 1 -27.127 -32.490 -0.338 1.00108.61 O ANISOU 1077 O5' DT D 1 19170 14378 7720 -829 -2818 -67 O ATOM 1078 C5' DT D 1 -26.020 -33.377 -0.497 1.00104.37 C ANISOU 1078 C5' DT D 1 19050 13407 7198 -848 -2784 -252 C ATOM 1079 C4' DT D 1 -25.341 -33.661 0.836 1.00 94.55 C ANISOU 1079 C4' DT D 1 17857 11693 6373 -1065 -2738 -168 C ATOM 1080 O4' DT D 1 -24.290 -32.686 1.076 1.00 83.48 O ANISOU 1080 O4' DT D 1 16461 10211 5047 -839 -2354 26 O ATOM 1081 C3' DT D 1 -26.245 -33.594 2.065 1.00 91.44 C ANISOU 1081 C3' DT D 1 17108 11335 6301 -1397 -2889 -9 C ATOM 1082 O3' DT D 1 -25.746 -34.480 3.051 1.00 98.18 O ANISOU 1082 O3' DT D 1 18145 11710 7450 -1674 -2991 -37 O ATOM 1083 C2' DT D 1 -26.054 -32.152 2.507 1.00 83.55 C ANISOU 1083 C2' DT D 1 15808 10521 5417 -1189 -2590 277 C ATOM 1084 C1' DT D 1 -24.557 -32.017 2.292 1.00 79.12 C ANISOU 1084 C1' DT D 1 15573 9651 4837 -979 -2298 267 C ATOM 1085 N1 DT D 1 -24.078 -30.620 2.181 1.00 74.02 N ANISOU 1085 N1 DT D 1 14796 9149 4180 -716 -1938 505 N ATOM 1086 C2 DT D 1 -22.777 -30.402 1.818 1.00 77.16 C ANISOU 1086 C2 DT D 1 15460 9369 4489 -531 -1616 486 C ATOM 1087 O2 DT D 1 -21.987 -31.301 1.575 1.00 80.30 O ANISOU 1087 O2 DT D 1 16176 9540 4793 -510 -1621 246 O ATOM 1088 N3 DT D 1 -22.422 -29.089 1.743 1.00 78.26 N ANISOU 1088 N3 DT D 1 15480 9614 4643 -362 -1283 737 N ATOM 1089 C4 DT D 1 -23.200 -27.982 1.994 1.00 79.95 C ANISOU 1089 C4 DT D 1 15370 10048 4960 -312 -1278 989 C ATOM 1090 O4 DT D 1 -22.760 -26.833 1.889 1.00 77.98 O ANISOU 1090 O4 DT D 1 15091 9800 4736 -170 -982 1208 O ATOM 1091 C5 DT D 1 -24.563 -28.272 2.376 1.00 81.41 C ANISOU 1091 C5 DT D 1 15262 10465 5205 -439 -1640 957 C ATOM 1092 C7 DT D 1 -25.516 -27.152 2.672 1.00 81.95 C ANISOU 1092 C7 DT D 1 14956 10844 5336 -327 -1686 1159 C ATOM 1093 C6 DT D 1 -24.936 -29.568 2.451 1.00 74.71 C ANISOU 1093 C6 DT D 1 14501 9547 4337 -657 -1930 722 C ATOM 1094 P DG D 2 -26.622 -35.719 3.576 1.00109.13 P ANISOU 1094 P DG D 2 19569 12929 8966 -2155 -3361 -123 P ATOM 1095 OP1 DG D 2 -27.225 -36.391 2.402 1.00110.86 O ANISOU 1095 OP1 DG D 2 19931 13304 8889 -2157 -3584 -401 O ATOM 1096 OP2 DG D 2 -27.475 -35.225 4.680 1.00105.74 O ANISOU 1096 OP2 DG D 2 18678 12735 8762 -2416 -3364 110 O ATOM 1097 O5' DG D 2 -25.527 -36.690 4.221 1.00114.22 O ANISOU 1097 O5' DG D 2 20648 12930 9821 -2240 -3418 -175 O ATOM 1098 C5' DG D 2 -24.382 -37.077 3.461 1.00110.00 C ANISOU 1098 C5' DG D 2 20519 12137 9141 -1893 -3351 -417 C ATOM 1099 C4' DG D 2 -23.102 -36.896 4.263 1.00104.79 C ANISOU 1099 C4' DG D 2 19979 11157 8679 -1708 -3150 -360 C ATOM 1100 O4' DG D 2 -22.654 -35.516 4.176 1.00100.38 O ANISOU 1100 O4' DG D 2 19162 10912 8066 -1441 -2769 -216 O ATOM 1101 C3' DG D 2 -23.213 -37.194 5.757 1.00105.73 C ANISOU 1101 C3' DG D 2 20030 11005 9139 -2022 -3259 -142 C ATOM 1102 O3' DG D 2 -21.995 -37.768 6.206 1.00112.44 O ANISOU 1102 O3' DG D 2 21200 11417 10104 -1805 -3253 -262 O ATOM 1103 C2' DG D 2 -23.410 -35.802 6.349 1.00 94.33 C ANISOU 1103 C2' DG D 2 18095 9940 7807 -1998 -2986 114 C ATOM 1104 C1' DG D 2 -22.464 -35.008 5.475 1.00 89.84 C ANISOU 1104 C1' DG D 2 17593 9508 7035 -1551 -2663 6 C ATOM 1105 N9 DG D 2 -22.729 -33.578 5.456 1.00 87.01 N ANISOU 1105 N9 DG D 2 16829 9557 6673 -1433 -2390 220 N ATOM 1106 C8 DG D 2 -23.906 -32.939 5.779 1.00 87.01 C ANISOU 1106 C8 DG D 2 16388 9912 6758 -1589 -2447 411 C ATOM 1107 N7 DG D 2 -23.841 -31.639 5.662 1.00 82.88 N ANISOU 1107 N7 DG D 2 15599 9664 6227 -1356 -2184 566 N ATOM 1108 C5 DG D 2 -22.537 -31.404 5.236 1.00 83.17 C ANISOU 1108 C5 DG D 2 15920 9518 6164 -1099 -1901 504 C ATOM 1109 C6 DG D 2 -21.878 -30.186 4.939 1.00 81.26 C ANISOU 1109 C6 DG D 2 15611 9391 5875 -841 -1522 640 C ATOM 1110 O6 DG D 2 -22.334 -29.033 4.995 1.00 84.05 O ANISOU 1110 O6 DG D 2 15662 9983 6288 -756 -1401 854 O ATOM 1111 N1 DG D 2 -20.557 -30.399 4.537 1.00 79.16 N ANISOU 1111 N1 DG D 2 15687 8925 5466 -669 -1268 489 N ATOM 1112 C2 DG D 2 -19.956 -31.636 4.438 1.00 84.69 C ANISOU 1112 C2 DG D 2 16737 9361 6080 -661 -1409 196 C ATOM 1113 N2 DG D 2 -18.683 -31.649 4.031 1.00 86.36 N ANISOU 1113 N2 DG D 2 17180 9503 6129 -423 -1105 9 N ATOM 1114 N3 DG D 2 -20.564 -32.783 4.715 1.00 84.39 N ANISOU 1114 N3 DG D 2 16800 9145 6119 -867 -1811 75 N ATOM 1115 C4 DG D 2 -21.845 -32.591 5.105 1.00 85.16 C ANISOU 1115 C4 DG D 2 16582 9425 6351 -1118 -2020 262 C ATOM 1116 P DC D 3 -21.933 -38.585 7.587 1.00114.98 P ANISOU 1116 P DC D 3 21664 11321 10703 -2056 -3472 -94 P ATOM 1117 OP1 DC D 3 -22.203 -40.004 7.281 1.00105.60 O ANISOU 1117 OP1 DC D 3 20885 9762 9477 -2201 -3826 -218 O ATOM 1118 OP2 DC D 3 -22.746 -37.862 8.592 1.00114.20 O ANISOU 1118 OP2 DC D 3 21132 11493 10768 -2404 -3412 237 O ATOM 1119 O5' DC D 3 -20.414 -38.439 8.043 1.00 92.31 O ANISOU 1119 O5' DC D 3 18895 8249 7929 -1597 -3280 -231 O ATOM 1120 C5' DC D 3 -19.981 -37.240 8.631 1.00 77.33 C ANISOU 1120 C5' DC D 3 16659 6603 6121 -1475 -2966 -119 C ATOM 1121 C4' DC D 3 -18.839 -36.649 7.842 1.00 78.37 C ANISOU 1121 C4' DC D 3 16803 6881 6094 -1003 -2625 -389 C ATOM 1122 O4' DC D 3 -19.295 -35.444 7.172 1.00 70.57 O ANISOU 1122 O4' DC D 3 15547 6333 4934 -1030 -2363 -257 O ATOM 1123 C3' DC D 3 -17.659 -36.215 8.695 1.00 79.63 C ANISOU 1123 C3' DC D 3 16841 7001 6415 -712 -2384 -474 C ATOM 1124 O3' DC D 3 -16.464 -36.251 7.941 1.00 82.75 O ANISOU 1124 O3' DC D 3 17306 7440 6696 -270 -2131 -842 O ATOM 1125 C2' DC D 3 -18.038 -34.791 9.056 1.00 62.08 C ANISOU 1125 C2' DC D 3 14231 5147 4208 -849 -2121 -203 C ATOM 1126 C1' DC D 3 -18.675 -34.316 7.760 1.00 63.75 C ANISOU 1126 C1' DC D 3 14419 5646 4157 -890 -2021 -153 C ATOM 1127 N1 DC D 3 -19.688 -33.244 7.971 1.00 71.35 N ANISOU 1127 N1 DC D 3 14946 6959 5203 -1103 -1943 178 N ATOM 1128 C2 DC D 3 -19.315 -31.913 7.770 1.00 69.31 C ANISOU 1128 C2 DC D 3 14457 6965 4911 -924 -1553 301 C ATOM 1129 O2 DC D 3 -18.164 -31.667 7.402 1.00 68.89 O ANISOU 1129 O2 DC D 3 14592 6872 4712 -662 -1240 145 O ATOM 1130 N3 DC D 3 -20.228 -30.932 7.972 1.00 66.86 N ANISOU 1130 N3 DC D 3 13714 6958 4732 -1029 -1514 559 N ATOM 1131 C4 DC D 3 -21.463 -31.241 8.366 1.00 68.66 C ANISOU 1131 C4 DC D 3 13697 7312 5078 -1293 -1814 651 C ATOM 1132 N4 DC D 3 -22.327 -30.235 8.545 1.00 63.58 N ANISOU 1132 N4 DC D 3 12609 7021 4527 -1300 -1771 835 N ATOM 1133 C5 DC D 3 -21.867 -32.598 8.590 1.00 70.50 C ANISOU 1133 C5 DC D 3 14156 7308 5322 -1556 -2162 551 C ATOM 1134 C6 DC D 3 -20.951 -33.559 8.386 1.00 70.22 C ANISOU 1134 C6 DC D 3 14598 6888 5193 -1454 -2229 338 C ATOM 1135 P DT D 4 -15.050 -36.315 8.701 1.00 81.49 P ANISOU 1135 P DT D 4 16987 7206 6768 132 -1933 -1104 P ATOM 1136 OP1 DT D 4 -14.010 -36.501 7.668 1.00 82.55 O ANISOU 1136 OP1 DT D 4 17115 7495 6755 525 -1700 -1510 O ATOM 1137 OP2 DT D 4 -15.179 -37.260 9.827 1.00 87.49 O ANISOU 1137 OP2 DT D 4 17843 7623 7777 75 -2297 -998 O ATOM 1138 O5' DT D 4 -14.868 -34.859 9.329 1.00 74.22 O ANISOU 1138 O5' DT D 4 15731 6554 5916 81 -1547 -959 O ATOM 1139 C5' DT D 4 -14.089 -33.913 8.641 1.00 70.06 C ANISOU 1139 C5' DT D 4 15050 6330 5239 281 -1041 -1125 C ATOM 1140 C4' DT D 4 -14.108 -32.569 9.332 1.00 65.44 C ANISOU 1140 C4' DT D 4 13982 5978 4906 166 -686 -833 C ATOM 1141 O4' DT D 4 -15.452 -32.097 9.462 1.00 63.38 O ANISOU 1141 O4' DT D 4 13676 5799 4605 -192 -881 -379 O ATOM 1142 C3' DT D 4 -13.527 -32.527 10.747 1.00 61.89 C ANISOU 1142 C3' DT D 4 13175 5453 4888 290 -663 -900 C ATOM 1143 O3' DT D 4 -12.213 -31.979 10.675 1.00 60.68 O ANISOU 1143 O3' DT D 4 12705 5489 4861 581 -176 -1225 O ATOM 1144 C2' DT D 4 -14.507 -31.605 11.535 1.00 54.11 C ANISOU 1144 C2' DT D 4 11840 4611 4108 -21 -689 -427 C ATOM 1145 C1' DT D 4 -15.443 -31.093 10.441 1.00 60.07 C ANISOU 1145 C1' DT D 4 12768 5521 4534 -244 -677 -159 C ATOM 1146 N1 DT D 4 -16.854 -30.868 10.850 1.00 62.52 N ANISOU 1146 N1 DT D 4 13004 5929 4823 -573 -1000 232 N ATOM 1147 C2 DT D 4 -17.362 -29.596 10.820 1.00 54.86 C ANISOU 1147 C2 DT D 4 11743 5212 3888 -649 -812 519 C ATOM 1148 O2 DT D 4 -16.710 -28.614 10.520 1.00 56.58 O ANISOU 1148 O2 DT D 4 11797 5511 4190 -507 -381 517 O ATOM 1149 N3 DT D 4 -18.671 -29.504 11.165 1.00 58.91 N ANISOU 1149 N3 DT D 4 12035 5897 4452 -891 -1124 748 N ATOM 1150 C4 DT D 4 -19.528 -30.517 11.513 1.00 57.45 C ANISOU 1150 C4 DT D 4 11838 5673 4319 -1134 -1517 735 C ATOM 1151 O4 DT D 4 -20.702 -30.303 11.799 1.00 60.06 O ANISOU 1151 O4 DT D 4 11801 6259 4762 -1332 -1674 872 O ATOM 1152 C5 DT D 4 -18.947 -31.834 11.520 1.00 54.93 C ANISOU 1152 C5 DT D 4 11996 4985 3889 -1124 -1716 531 C ATOM 1153 C7 DT D 4 -19.780 -33.022 11.879 1.00 53.11 C ANISOU 1153 C7 DT D 4 11876 4584 3720 -1443 -2118 551 C ATOM 1154 C6 DT D 4 -17.652 -31.949 11.178 1.00 61.00 C ANISOU 1154 C6 DT D 4 13059 5577 4540 -807 -1494 279 C ATOM 1155 P DT D 5 -11.404 -31.555 11.995 1.00 63.20 P ANISOU 1155 P DT D 5 12504 5881 5628 762 7 -1367 P ATOM 1156 OP1 DT D 5 -9.980 -31.570 11.592 1.00 61.15 O ANISOU 1156 OP1 DT D 5 12090 5795 5348 1109 382 -1896 O ATOM 1157 OP2 DT D 5 -11.872 -32.345 13.152 1.00 73.47 O ANISOU 1157 OP2 DT D 5 13893 6935 7087 758 -471 -1261 O ATOM 1158 O5' DT D 5 -11.862 -30.046 12.265 1.00 68.41 O ANISOU 1158 O5' DT D 5 12728 6761 6503 493 326 -982 O ATOM 1159 C5' DT D 5 -11.845 -29.121 11.205 1.00 59.01 C ANISOU 1159 C5' DT D 5 11546 5737 5136 360 723 -855 C ATOM 1160 C4' DT D 5 -12.430 -27.793 11.634 1.00 56.89 C ANISOU 1160 C4' DT D 5 10952 5562 5102 138 883 -467 C ATOM 1161 O4' DT D 5 -13.859 -27.905 11.840 1.00 55.16 O ANISOU 1161 O4' DT D 5 10884 5294 4780 -68 440 -75 O ATOM 1162 C3' DT D 5 -11.852 -27.194 12.916 1.00 52.80 C ANISOU 1162 C3' DT D 5 9874 5112 5076 226 1041 -593 C ATOM 1163 O3' DT D 5 -11.519 -25.854 12.641 1.00 54.32 O ANISOU 1163 O3' DT D 5 9818 5401 5420 108 1512 -502 O ATOM 1164 C2' DT D 5 -13.003 -27.306 13.929 1.00 43.76 C ANISOU 1164 C2' DT D 5 8634 3936 4057 110 581 -281 C ATOM 1165 C1' DT D 5 -14.218 -27.224 13.019 1.00 49.66 C ANISOU 1165 C1' DT D 5 9754 4672 4443 -124 379 93 C ATOM 1166 N1 DT D 5 -15.442 -27.877 13.548 1.00 51.49 N ANISOU 1166 N1 DT D 5 10089 4900 4576 -294 -152 330 N ATOM 1167 C2 DT D 5 -16.603 -27.159 13.579 1.00 44.08 C ANISOU 1167 C2 DT D 5 9048 4125 3575 -479 -305 674 C ATOM 1168 O2 DT D 5 -16.673 -26.011 13.218 1.00 48.93 O ANISOU 1168 O2 DT D 5 9544 4818 4228 -466 -57 812 O ATOM 1169 N3 DT D 5 -17.690 -27.841 14.043 1.00 50.07 N ANISOU 1169 N3 DT D 5 9861 4956 4207 -684 -771 842 N ATOM 1170 C4 DT D 5 -17.740 -29.150 14.469 1.00 52.38 C ANISOU 1170 C4 DT D 5 10367 5095 4441 -768 -1091 755 C ATOM 1171 O4 DT D 5 -18.784 -29.666 14.870 1.00 50.57 O ANISOU 1171 O4 DT D 5 10104 4967 4143 -1032 -1449 909 O ATOM 1172 C5 DT D 5 -16.478 -29.864 14.413 1.00 56.23 C ANISOU 1172 C5 DT D 5 11037 5320 5008 -513 -947 410 C ATOM 1173 C7 DT D 5 -16.396 -31.305 14.857 1.00 44.99 C ANISOU 1173 C7 DT D 5 9949 3619 3526 -526 -1313 294 C ATOM 1174 C6 DT D 5 -15.400 -29.199 13.952 1.00 43.76 C ANISOU 1174 C6 DT D 5 9334 3756 3538 -271 -490 189 C ATOM 1175 P DC D 6 -10.954 -24.873 13.772 1.00 61.40 P ANISOU 1175 P DC D 6 10103 6380 6848 136 1761 -628 P ATOM 1176 OP1 DC D 6 -9.988 -24.038 13.021 1.00 60.41 O ANISOU 1176 OP1 DC D 6 9886 6320 6748 36 2361 -775 O ATOM 1177 OP2 DC D 6 -10.566 -25.563 15.031 1.00 55.27 O ANISOU 1177 OP2 DC D 6 9017 5655 6329 379 1523 -924 O ATOM 1178 O5' DC D 6 -12.226 -24.014 14.155 1.00 57.52 O ANISOU 1178 O5' DC D 6 9550 5850 6454 -35 1532 -161 O ATOM 1179 C5' DC D 6 -12.915 -23.301 13.165 1.00 54.97 C ANISOU 1179 C5' DC D 6 9546 5459 5881 -211 1609 208 C ATOM 1180 C4' DC D 6 -14.041 -22.552 13.810 1.00 51.04 C ANISOU 1180 C4' DC D 6 8880 4984 5530 -262 1318 527 C ATOM 1181 O4' DC D 6 -15.050 -23.508 14.233 1.00 49.81 O ANISOU 1181 O4' DC D 6 8806 4929 5189 -264 780 638 O ATOM 1182 C3' DC D 6 -13.621 -21.786 15.070 1.00 46.80 C ANISOU 1182 C3' DC D 6 7758 4495 5528 -185 1420 359 C ATOM 1183 O3' DC D 6 -14.080 -20.454 14.985 1.00 47.18 O ANISOU 1183 O3' DC D 6 7756 4454 5716 -252 1506 601 O ATOM 1184 C2' DC D 6 -14.277 -22.564 16.223 1.00 40.99 C ANISOU 1184 C2' DC D 6 6790 3937 4848 -93 931 344 C ATOM 1185 C1' DC D 6 -15.478 -23.187 15.531 1.00 43.42 C ANISOU 1185 C1' DC D 6 7540 4264 4692 -220 555 658 C ATOM 1186 N1 DC D 6 -16.005 -24.435 16.165 1.00 36.00 N ANISOU 1186 N1 DC D 6 6634 3426 3620 -248 117 655 N ATOM 1187 C2 DC D 6 -17.355 -24.485 16.531 1.00 42.69 C ANISOU 1187 C2 DC D 6 7425 4482 4314 -386 -303 924 C ATOM 1188 O2 DC D 6 -18.054 -23.483 16.356 1.00 41.26 O ANISOU 1188 O2 DC D 6 7141 4415 4121 -397 -331 1113 O ATOM 1189 N3 DC D 6 -17.856 -25.624 17.070 1.00 37.26 N ANISOU 1189 N3 DC D 6 6805 3871 3482 -508 -673 960 N ATOM 1190 C4 DC D 6 -17.065 -26.684 17.237 1.00 42.62 C ANISOU 1190 C4 DC D 6 7670 4353 4170 -439 -672 754 C ATOM 1191 N4 DC D 6 -17.606 -27.785 17.776 1.00 38.66 N ANISOU 1191 N4 DC D 6 7311 3857 3521 -596 -1053 841 N ATOM 1192 C5 DC D 6 -15.679 -26.662 16.856 1.00 39.60 C ANISOU 1192 C5 DC D 6 7342 3773 3931 -208 -285 433 C ATOM 1193 C6 DC D 6 -15.201 -25.526 16.324 1.00 40.19 C ANISOU 1193 C6 DC D 6 7284 3848 4140 -150 117 390 C ATOM 1194 P DC D 7 -13.676 -19.357 16.092 1.00 46.64 P ANISOU 1194 P DC D 7 7122 4377 6220 -191 1646 425 P ATOM 1195 OP1 DC D 7 -13.734 -18.050 15.380 1.00 51.96 O ANISOU 1195 OP1 DC D 7 8017 4782 6941 -316 1914 658 O ATOM 1196 OP2 DC D 7 -12.433 -19.778 16.781 1.00 47.46 O ANISOU 1196 OP2 DC D 7 6826 4580 6626 -105 1884 -41 O ATOM 1197 O5' DC D 7 -14.891 -19.397 17.121 1.00 44.94 O ANISOU 1197 O5' DC D 7 6633 4394 6047 -65 1096 557 O ATOM 1198 C5' DC D 7 -16.195 -19.068 16.654 1.00 45.98 C ANISOU 1198 C5' DC D 7 7032 4557 5879 -83 773 923 C ATOM 1199 C4' DC D 7 -17.254 -19.434 17.671 1.00 44.47 C ANISOU 1199 C4' DC D 7 6511 4731 5655 -1 261 965 C ATOM 1200 O4' DC D 7 -17.215 -20.841 17.917 1.00 41.51 O ANISOU 1200 O4' DC D 7 6189 4499 5087 -69 90 895 O ATOM 1201 C3' DC D 7 -17.112 -18.774 19.050 1.00 45.01 C ANISOU 1201 C3' DC D 7 5940 4977 6183 165 199 746 C ATOM 1202 O3' DC D 7 -18.170 -17.838 19.232 1.00 41.46 O ANISOU 1202 O3' DC D 7 5366 4659 5726 276 -88 901 O ATOM 1203 C2' DC D 7 -17.213 -19.949 20.050 1.00 32.48 C ANISOU 1203 C2' DC D 7 4076 3722 4542 180 -65 632 C ATOM 1204 C1' DC D 7 -17.775 -21.061 19.174 1.00 34.63 C ANISOU 1204 C1' DC D 7 4869 3969 4318 -12 -244 857 C ATOM 1205 N1 DC D 7 -17.416 -22.435 19.575 1.00 38.09 N ANISOU 1205 N1 DC D 7 5376 4445 4652 -64 -346 756 N ATOM 1206 C2 DC D 7 -18.398 -23.267 20.112 1.00 40.50 C ANISOU 1206 C2 DC D 7 5654 5028 4706 -206 -767 920 C ATOM 1207 O2 DC D 7 -19.531 -22.808 20.294 1.00 40.29 O ANISOU 1207 O2 DC D 7 5447 5308 4553 -271 -1033 1096 O ATOM 1208 N3 DC D 7 -18.079 -24.547 20.426 1.00 39.01 N ANISOU 1208 N3 DC D 7 5646 4771 4406 -270 -880 870 N ATOM 1209 C4 DC D 7 -16.839 -24.997 20.216 1.00 40.43 C ANISOU 1209 C4 DC D 7 5996 4659 4706 -119 -620 618 C ATOM 1210 N4 DC D 7 -16.568 -26.270 20.546 1.00 36.04 N ANISOU 1210 N4 DC D 7 5673 3996 4024 -123 -795 565 N ATOM 1211 C5 DC D 7 -15.826 -24.168 19.649 1.00 37.00 C ANISOU 1211 C5 DC D 7 5515 4037 4506 32 -176 400 C ATOM 1212 C6 DC D 7 -16.158 -22.906 19.337 1.00 33.57 C ANISOU 1212 C6 DC D 7 4938 3630 4189 13 -38 504 C HETATM 1213 N1 5CM D 8 -18.785 -20.560 23.784 1.00 34.66 N ANISOU 1213 N1 5CM D 8 2931 5319 4919 413 -984 504 N HETATM 1214 C2 5CM D 8 -19.420 -21.868 23.940 1.00 40.18 C ANISOU 1214 C2 5CM D 8 3886 6167 5213 175 -1212 673 C HETATM 1215 N3 5CM D 8 -18.611 -23.084 23.820 1.00 33.25 N ANISOU 1215 N3 5CM D 8 3312 5060 4263 102 -1162 688 N HETATM 1216 C4 5CM D 8 -17.235 -23.000 23.536 1.00 35.15 C ANISOU 1216 C4 5CM D 8 3647 4928 4780 292 -792 407 C HETATM 1217 C5 5CM D 8 -16.606 -21.689 23.375 1.00 31.20 C ANISOU 1217 C5 5CM D 8 2884 4303 4667 468 -470 183 C HETATM 1218 C5A 5CM D 8 -15.119 -21.619 23.081 1.00 27.16 C ANISOU 1218 C5A 5CM D 8 2405 3484 4429 600 -42 -158 C HETATM 1219 C6 5CM D 8 -17.398 -20.470 23.502 1.00 34.26 C ANISOU 1219 C6 5CM D 8 2983 4868 5167 510 -574 257 C HETATM 1220 O2 5CM D 8 -20.615 -21.941 24.192 1.00 34.59 O ANISOU 1220 O2 5CM D 8 3295 5563 4285 73 -1281 640 O HETATM 1221 N4 5CM D 8 -16.459 -24.192 23.425 1.00 31.65 N ANISOU 1221 N4 5CM D 8 3551 4241 4234 309 -747 315 N HETATM 1222 C1' 5CM D 8 -19.608 -19.384 23.903 1.00 31.30 C ANISOU 1222 C1' 5CM D 8 2421 4956 4515 506 -1051 390 C HETATM 1223 C2' 5CM D 8 -18.807 -18.074 24.226 1.00 29.83 C ANISOU 1223 C2' 5CM D 8 2002 4719 4613 723 -735 184 C HETATM 1224 C3' 5CM D 8 -19.891 -17.069 23.930 1.00 37.11 C ANISOU 1224 C3' 5CM D 8 2980 5693 5427 809 -929 199 C HETATM 1225 C4' 5CM D 8 -20.509 -17.535 22.828 1.00 41.88 C ANISOU 1225 C4' 5CM D 8 3793 6217 5903 692 -1197 615 C HETATM 1226 O4' 5CM D 8 -20.122 -19.101 22.755 1.00 39.72 O ANISOU 1226 O4' 5CM D 8 3722 5961 5410 436 -1159 732 O HETATM 1227 O3' 5CM D 8 -20.869 -17.213 25.031 1.00 39.10 O ANISOU 1227 O3' 5CM D 8 3304 5709 5845 535 -1101 259 O HETATM 1228 C5' 5CM D 8 -20.084 -16.846 21.572 1.00 30.04 C ANISOU 1228 C5' 5CM D 8 2783 4158 4474 683 -933 756 C HETATM 1229 O5' 5CM D 8 -18.656 -16.884 21.518 1.00 34.69 O ANISOU 1229 O5' 5CM D 8 3418 4360 5401 630 -472 564 O HETATM 1230 P 5CM D 8 -17.953 -16.537 20.143 1.00 38.36 P ANISOU 1230 P 5CM D 8 4480 4252 5842 484 -52 688 P HETATM 1231 OP1 5CM D 8 -18.665 -15.364 19.488 1.00 43.14 O ANISOU 1231 OP1 5CM D 8 5364 4644 6385 583 -157 904 O HETATM 1232 OP2 5CM D 8 -16.474 -16.349 20.352 1.00 35.73 O ANISOU 1232 OP2 5CM D 8 3983 3659 5935 443 423 379 O ATOM 1233 P DG D 9 -20.986 -16.131 26.214 1.00 46.54 P ANISOU 1233 P DG D 9 6176 4663 6843 949 677 26 P ATOM 1234 OP1 DG D 9 -21.539 -14.863 25.671 1.00 48.21 O ANISOU 1234 OP1 DG D 9 6478 4604 7234 994 895 73 O ATOM 1235 OP2 DG D 9 -19.747 -16.112 26.999 1.00 49.27 O ANISOU 1235 OP2 DG D 9 6760 4834 7125 667 59 -121 O ATOM 1236 O5' DG D 9 -22.075 -16.783 27.169 1.00 45.48 O ANISOU 1236 O5' DG D 9 6511 4563 6208 1343 1032 -104 O ATOM 1237 C5' DG D 9 -23.315 -17.208 26.634 1.00 37.38 C ANISOU 1237 C5' DG D 9 5247 3840 5114 1588 1582 38 C ATOM 1238 C4' DG D 9 -23.892 -18.312 27.482 1.00 31.05 C ANISOU 1238 C4' DG D 9 4602 3290 3903 1612 1559 8 C ATOM 1239 O4' DG D 9 -23.123 -19.528 27.242 1.00 45.35 O ANISOU 1239 O4' DG D 9 6000 5380 5853 1512 1418 79 O ATOM 1240 C3' DG D 9 -23.830 -18.051 28.978 1.00 39.86 C ANISOU 1240 C3' DG D 9 6503 4046 4596 1852 1470 -253 C ATOM 1241 O3' DG D 9 -25.044 -18.514 29.614 1.00 40.89 O ANISOU 1241 O3' DG D 9 6706 4397 4431 1848 1567 -153 O ATOM 1242 C2' DG D 9 -22.577 -18.827 29.432 1.00 45.83 C ANISOU 1242 C2' DG D 9 7245 4820 5349 1735 1056 -321 C ATOM 1243 C1' DG D 9 -22.493 -19.969 28.422 1.00 36.04 C ANISOU 1243 C1' DG D 9 5245 4039 4412 1685 1232 -78 C ATOM 1244 N9 DG D 9 -21.133 -20.369 28.055 1.00 41.20 N ANISOU 1244 N9 DG D 9 5461 4818 5374 1353 766 -8 N ATOM 1245 C8 DG D 9 -20.103 -19.554 27.661 1.00 40.79 C ANISOU 1245 C8 DG D 9 5265 4613 5619 1030 354 -11 C ATOM 1246 N7 DG D 9 -19.008 -20.209 27.358 1.00 39.44 N ANISOU 1246 N7 DG D 9 4647 4661 5676 793 8 83 N ATOM 1247 C5 DG D 9 -19.341 -21.542 27.540 1.00 33.92 C ANISOU 1247 C5 DG D 9 3791 4251 4845 978 212 144 C ATOM 1248 C6 DG D 9 -18.563 -22.712 27.348 1.00 27.84 C ANISOU 1248 C6 DG D 9 2567 3780 4230 882 23 252 C ATOM 1249 O6 DG D 9 -17.379 -22.799 26.987 1.00 31.07 O ANISOU 1249 O6 DG D 9 2608 4291 4907 615 -380 317 O ATOM 1250 N1 DG D 9 -19.280 -23.856 27.645 1.00 28.55 N ANISOU 1250 N1 DG D 9 2661 4054 4132 1137 346 289 N ATOM 1251 C2 DG D 9 -20.596 -23.875 28.058 1.00 35.84 C ANISOU 1251 C2 DG D 9 3954 4921 4743 1436 798 245 C ATOM 1252 N2 DG D 9 -21.127 -25.082 28.298 1.00 28.16 N ANISOU 1252 N2 DG D 9 3046 4038 3615 1311 847 261 N ATOM 1253 N3 DG D 9 -21.334 -22.789 28.236 1.00 37.84 N ANISOU 1253 N3 DG D 9 4617 4930 4830 1542 985 148 N ATOM 1254 C4 DG D 9 -20.644 -21.663 27.962 1.00 37.35 C ANISOU 1254 C4 DG D 9 4579 4649 4962 1307 675 96 C HETATM 1255 N1 5CM D 10 -20.592 -22.244 31.636 1.00 49.04 N ANISOU 1255 N1 5CM D 10 7631 5752 5252 1590 185 -287 N HETATM 1256 C2 5CM D 10 -19.585 -23.263 31.335 1.00 45.61 C ANISOU 1256 C2 5CM D 10 6691 5573 5067 1408 -97 -136 C HETATM 1257 N3 5CM D 10 -18.275 -22.862 30.840 1.00 43.04 N ANISOU 1257 N3 5CM D 10 6042 5226 5084 1054 -573 -114 N HETATM 1258 C4 5CM D 10 -17.966 -21.497 30.639 1.00 37.44 C ANISOU 1258 C4 5CM D 10 5505 4232 4487 858 -773 -228 C HETATM 1259 C5 5CM D 10 -18.963 -20.473 30.930 1.00 42.71 C ANISOU 1259 C5 5CM D 10 6693 4599 4936 1034 -495 -386 C HETATM 1260 C5A 5CM D 10 -18.635 -18.990 30.724 1.00 41.49 C ANISOU 1260 C5A 5CM D 10 6748 4082 4934 825 -710 -509 C HETATM 1261 C6 5CM D 10 -20.280 -20.882 31.427 1.00 42.81 C ANISOU 1261 C6 5CM D 10 7023 4656 4588 1417 -6 -415 C HETATM 1262 O2 5CM D 10 -19.819 -24.440 31.498 1.00 53.51 O ANISOU 1262 O2 5CM D 10 7533 6801 5997 1550 59 -22 O HETATM 1263 N4 5CM D 10 -16.675 -21.149 30.164 1.00 41.63 N ANISOU 1263 N4 5CM D 10 5694 4772 5349 494 -1247 -177 N HETATM 1264 C1' 5CM D 10 -21.900 -22.629 32.100 1.00 42.91 C ANISOU 1264 C1' 5CM D 10 7142 5038 4125 1946 666 -289 C HETATM 1265 C2' 5CM D 10 -22.298 -22.070 33.506 1.00 47.23 C ANISOU 1265 C2' 5CM D 10 8497 5332 4117 2120 596 -516 C HETATM 1266 C3' 5CM D 10 -23.814 -21.960 33.423 1.00 55.07 C ANISOU 1266 C3' 5CM D 10 9394 6404 5127 2219 1036 -354 C HETATM 1267 C4' 5CM D 10 -24.136 -22.120 32.136 1.00 48.38 C ANISOU 1267 C4' 5CM D 10 7933 5737 4713 2060 1223 -155 C HETATM 1268 O4' 5CM D 10 -22.765 -22.094 31.313 1.00 40.91 O ANISOU 1268 O4' 5CM D 10 6761 4776 4008 2061 1082 -250 O HETATM 1269 O3' 5CM D 10 -24.481 -23.091 34.121 1.00 56.71 O ANISOU 1269 O3' 5CM D 10 9498 6805 5243 2256 1097 -171 O HETATM 1270 C5' 5CM D 10 -25.057 -21.053 31.649 1.00 40.40 C ANISOU 1270 C5' 5CM D 10 6881 4631 3838 1981 1377 -114 C HETATM 1271 O5' 5CM D 10 -24.405 -19.804 31.692 1.00 56.58 O ANISOU 1271 O5' 5CM D 10 9330 6346 5822 2064 1299 -356 O HETATM 1272 P 5CM D 10 -25.180 -18.495 31.213 1.00 46.24 P ANISOU 1272 P 5CM D 10 8049 4881 4639 2034 1462 -339 P HETATM 1273 OP1 5CM D 10 -26.625 -18.604 31.626 1.00 51.02 O ANISOU 1273 OP1 5CM D 10 8627 5630 5129 2049 1602 -172 O HETATM 1274 OP2 5CM D 10 -24.449 -17.311 31.792 1.00 52.49 O ANISOU 1274 OP2 5CM D 10 9478 5181 5287 2099 1242 -666 O ATOM 1275 P DG D 11 -24.598 -23.126 35.718 1.00 58.95 P ANISOU 1275 P DG D 11 10335 6985 5080 2408 956 -288 P ATOM 1276 OP1 DG D 11 -25.780 -23.959 36.019 1.00 59.87 O ANISOU 1276 OP1 DG D 11 10192 7246 5310 2421 1138 -63 O ATOM 1277 OP2 DG D 11 -24.443 -21.757 36.266 1.00 55.15 O ANISOU 1277 OP2 DG D 11 10394 6209 4353 2436 818 -549 O ATOM 1278 O5' DG D 11 -23.286 -23.917 36.187 1.00 58.48 O ANISOU 1278 O5' DG D 11 10443 7008 4768 2434 633 -383 O ATOM 1279 C5' DG D 11 -23.076 -25.266 35.806 1.00 50.45 C ANISOU 1279 C5' DG D 11 8992 6258 3917 2439 695 -175 C ATOM 1280 C4' DG D 11 -21.677 -25.715 36.197 1.00 47.24 C ANISOU 1280 C4' DG D 11 8704 5934 3313 2361 226 -230 C ATOM 1281 O4' DG D 11 -20.698 -25.036 35.358 1.00 48.46 O ANISOU 1281 O4' DG D 11 8544 5976 3894 2050 -90 -278 O ATOM 1282 C3' DG D 11 -21.264 -25.385 37.639 1.00 54.69 C ANISOU 1282 C3' DG D 11 10263 6763 3756 2362 -157 -402 C ATOM 1283 O3' DG D 11 -20.393 -26.374 38.100 1.00 65.53 O ANISOU 1283 O3' DG D 11 11466 8310 5123 2265 -493 -253 O ATOM 1284 C2' DG D 11 -20.498 -24.085 37.453 1.00 53.16 C ANISOU 1284 C2' DG D 11 10211 6289 3697 2098 -527 -625 C ATOM 1285 C1' DG D 11 -19.729 -24.461 36.205 1.00 52.31 C ANISOU 1285 C1' DG D 11 9390 6300 4186 1858 -632 -442 C ATOM 1286 N9 DG D 11 -19.076 -23.347 35.540 1.00 52.81 N ANISOU 1286 N9 DG D 11 9351 6153 4561 1582 -882 -556 N ATOM 1287 C8 DG D 11 -19.450 -22.026 35.565 1.00 53.11 C ANISOU 1287 C8 DG D 11 9777 5880 4522 1577 -835 -773 C ATOM 1288 N7 DG D 11 -18.650 -21.251 34.890 1.00 53.13 N ANISOU 1288 N7 DG D 11 9565 5737 4885 1275 -1122 -804 N ATOM 1289 C5 DG D 11 -17.679 -22.113 34.398 1.00 50.94 C ANISOU 1289 C5 DG D 11 8714 5720 4920 1076 -1375 -601 C ATOM 1290 C6 DG D 11 -16.544 -21.851 33.600 1.00 49.64 C ANISOU 1290 C6 DG D 11 8084 5586 5191 730 -1737 -519 C ATOM 1291 O6 DG D 11 -16.156 -20.766 33.150 1.00 49.15 O ANISOU 1291 O6 DG D 11 8021 5308 5345 502 -1919 -598 O ATOM 1292 N1 DG D 11 -15.827 -23.014 33.328 1.00 49.80 N ANISOU 1292 N1 DG D 11 7590 5926 5404 663 -1885 -310 N ATOM 1293 C2 DG D 11 -16.157 -24.267 33.778 1.00 47.78 C ANISOU 1293 C2 DG D 11 7292 5892 4968 891 -1713 -192 C ATOM 1294 N2 DG D 11 -15.335 -25.268 33.417 1.00 44.33 N ANISOU 1294 N2 DG D 11 6335 5720 4789 798 -1895 2 N ATOM 1295 N3 DG D 11 -17.217 -24.524 34.526 1.00 46.41 N ANISOU 1295 N3 DG D 11 7549 5686 4399 1193 -1381 -249 N ATOM 1296 C4 DG D 11 -17.930 -23.405 34.791 1.00 50.83 C ANISOU 1296 C4 DG D 11 8597 5973 4743 1272 -1228 -456 C ATOM 1297 P DA D 12 -20.767 -27.279 39.367 1.00 62.30 P ANISOU 1297 P DA D 12 11249 8032 4388 2421 -436 -150 P ATOM 1298 OP1 DA D 12 -21.996 -28.003 38.972 1.00 71.43 O ANISOU 1298 OP1 DA D 12 12063 9264 5815 2573 115 21 O ATOM 1299 OP2 DA D 12 -20.713 -26.452 40.590 1.00 61.32 O ANISOU 1299 OP2 DA D 12 11639 7752 3908 2385 -655 -372 O ATOM 1300 O5' DA D 12 -19.571 -28.337 39.414 1.00 54.91 O ANISOU 1300 O5' DA D 12 10037 7307 3518 2313 -846 61 O ATOM 1301 C5' DA D 12 -19.383 -29.204 38.305 1.00 51.05 C ANISOU 1301 C5' DA D 12 8906 6951 3539 2268 -700 280 C ATOM 1302 C4' DA D 12 -17.912 -29.500 38.062 1.00 48.42 C ANISOU 1302 C4' DA D 12 8196 6680 3521 1998 -1206 363 C ATOM 1303 O4' DA D 12 -17.261 -28.368 37.426 1.00 52.37 O ANISOU 1303 O4' DA D 12 8608 7028 4262 1733 -1460 190 O ATOM 1304 C3' DA D 12 -17.075 -29.824 39.286 1.00 53.64 C ANISOU 1304 C3' DA D 12 9118 7415 3845 1949 -1674 406 C ATOM 1305 O3' DA D 12 -16.125 -30.779 38.885 1.00 51.62 O ANISOU 1305 O3' DA D 12 8342 7319 3954 1844 -1897 632 O ATOM 1306 C2' DA D 12 -16.423 -28.471 39.610 1.00 53.68 C ANISOU 1306 C2' DA D 12 9460 7241 3696 1712 -2089 133 C ATOM 1307 C1' DA D 12 -16.173 -27.925 38.214 1.00 54.24 C ANISOU 1307 C1' DA D 12 9082 7222 4306 1523 -2032 96 C ATOM 1308 N9 DA D 12 -16.147 -26.473 38.118 1.00 57.60 N ANISOU 1308 N9 DA D 12 9810 7390 4684 1365 -2154 -174 N ATOM 1309 C8 DA D 12 -17.039 -25.595 38.666 1.00 57.25 C ANISOU 1309 C8 DA D 12 10341 7144 4269 1507 -1956 -405 C ATOM 1310 N7 DA D 12 -16.799 -24.345 38.370 1.00 62.88 N ANISOU 1310 N7 DA D 12 11208 7604 5080 1316 -2114 -618 N ATOM 1311 C5 DA D 12 -15.682 -24.401 37.556 1.00 63.13 C ANISOU 1311 C5 DA D 12 10713 7703 5572 1014 -2437 -503 C ATOM 1312 C6 DA D 12 -14.920 -23.401 36.910 1.00 60.74 C ANISOU 1312 C6 DA D 12 10261 7233 5585 691 -2735 -596 C ATOM 1313 N6 DA D 12 -15.193 -22.087 36.989 1.00 60.32 N ANISOU 1313 N6 DA D 12 10618 6853 5448 615 -2753 -846 N ATOM 1314 N1 DA D 12 -13.864 -23.804 36.175 1.00 53.69 N ANISOU 1314 N1 DA D 12 8776 6518 5105 452 -3012 -412 N ATOM 1315 C2 DA D 12 -13.588 -25.112 36.101 1.00 55.77 C ANISOU 1315 C2 DA D 12 8644 7078 5467 547 -2988 -174 C ATOM 1316 N3 DA D 12 -14.227 -26.137 36.664 1.00 52.50 N ANISOU 1316 N3 DA D 12 8333 6805 4810 838 -2725 -70 N ATOM 1317 C4 DA D 12 -15.274 -25.710 37.382 1.00 59.34 C ANISOU 1317 C4 DA D 12 9773 7514 5259 1053 -2457 -237 C ATOM 1318 P DA D 13 -15.122 -31.468 39.913 1.00 57.19 P ANISOU 1318 P DA D 13 9073 8168 4489 1770 -2330 785 P ATOM 1319 OP1 DA D 13 -15.063 -32.872 39.451 1.00 70.11 O ANISOU 1319 OP1 DA D 13 10202 9936 6500 1852 -2131 1068 O ATOM 1320 OP2 DA D 13 -15.480 -31.146 41.312 1.00 64.86 O ANISOU 1320 OP2 DA D 13 10596 9115 4935 1814 -2353 672 O ATOM 1321 O5' DA D 13 -13.714 -30.805 39.564 1.00 71.67 O ANISOU 1321 O5' DA D 13 10681 9996 6554 1428 -2866 709 O ATOM 1322 C5' DA D 13 -13.185 -30.960 38.261 1.00 59.65 C ANISOU 1322 C5' DA D 13 8564 8517 5584 1305 -2887 788 C ATOM 1323 C4' DA D 13 -11.807 -30.336 38.148 1.00 54.81 C ANISOU 1323 C4' DA D 13 7732 7935 5158 936 -3319 731 C ATOM 1324 O4' DA D 13 -11.920 -28.895 38.030 1.00 59.46 O ANISOU 1324 O4' DA D 13 8657 8305 5631 779 -3487 462 O ATOM 1325 C3' DA D 13 -10.865 -30.589 39.312 1.00 58.96 C ANISOU 1325 C3' DA D 13 8364 8601 5438 822 -3625 789 C ATOM 1326 O3' DA D 13 -9.560 -30.744 38.797 1.00 60.53 O ANISOU 1326 O3' DA D 13 8049 8960 5991 614 -3781 859 O ATOM 1327 C2' DA D 13 -10.995 -29.308 40.144 1.00 66.28 C ANISOU 1327 C2' DA D 13 9902 9345 5938 705 -3858 504 C ATOM 1328 C1' DA D 13 -11.169 -28.265 39.053 1.00 64.21 C ANISOU 1328 C1' DA D 13 9578 8877 5940 570 -3848 332 C ATOM 1329 N9 DA D 13 -11.902 -27.069 39.471 1.00 68.54 N ANISOU 1329 N9 DA D 13 10761 9155 6126 585 -3861 34 N ATOM 1330 C8 DA D 13 -12.974 -27.005 40.317 1.00 71.26 C ANISOU 1330 C8 DA D 13 11668 9418 5990 850 -3621 -85 C ATOM 1331 N7 DA D 13 -13.444 -25.786 40.486 1.00 72.50 N ANISOU 1331 N7 DA D 13 12308 9311 5926 816 -3614 -383 N ATOM 1332 C5 DA D 13 -12.635 -25.001 39.682 1.00 69.41 C ANISOU 1332 C5 DA D 13 11667 8803 5902 492 -3910 -450 C ATOM 1333 C6 DA D 13 -12.607 -23.609 39.414 1.00 71.05 C ANISOU 1333 C6 DA D 13 12119 8704 6172 287 -4016 -712 C ATOM 1334 N6 DA D 13 -13.458 -22.724 39.951 1.00 68.01 N ANISOU 1334 N6 DA D 13 12338 8052 5451 410 -3836 -993 N ATOM 1335 N1 DA D 13 -11.662 -23.162 38.567 1.00 71.53 N ANISOU 1335 N1 DA D 13 11766 8742 6671 -44 -4305 -663 N ATOM 1336 C2 DA D 13 -10.803 -24.036 38.028 1.00 71.30 C ANISOU 1336 C2 DA D 13 11073 8998 7021 -142 -4363 -381 C ATOM 1337 N3 DA D 13 -10.730 -25.353 38.200 1.00 67.38 N ANISOU 1337 N3 DA D 13 10286 8784 6530 40 -4234 -145 N ATOM 1338 C4 DA D 13 -11.681 -25.777 39.048 1.00 67.23 C ANISOU 1338 C4 DA D 13 10722 8760 6063 346 -4042 -186 C ATOM 1339 P DT D 14 -8.322 -31.050 39.762 1.00 76.90 P ANISOU 1339 P DT D 14 10082 11237 7901 512 -4087 929 P ATOM 1340 OP1 DT D 14 -7.452 -31.970 39.003 1.00 82.14 O ANISOU 1340 OP1 DT D 14 10164 12083 8960 558 -3963 1062 O ATOM 1341 OP2 DT D 14 -8.824 -31.417 41.105 1.00 75.84 O ANISOU 1341 OP2 DT D 14 10381 11146 7289 662 -4137 991 O ATOM 1342 O5' DT D 14 -7.574 -29.643 39.863 1.00 88.78 O ANISOU 1342 O5' DT D 14 11750 12629 9353 184 -4420 697 O ATOM 1343 C5' DT D 14 -7.220 -28.950 38.670 1.00 79.38 C ANISOU 1343 C5' DT D 14 10263 11346 8554 0 -4374 610 C ATOM 1344 C4' DT D 14 -6.704 -27.555 38.982 1.00 80.33 C ANISOU 1344 C4' DT D 14 10662 11304 8558 -300 -4693 400 C ATOM 1345 O4' DT D 14 -7.813 -26.682 39.339 1.00 73.79 O ANISOU 1345 O4' DT D 14 10407 10188 7443 -273 -4708 191 O ATOM 1346 C3' DT D 14 -5.719 -27.460 40.156 1.00 90.37 C ANISOU 1346 C3' DT D 14 12087 12712 9539 -431 -5036 380 C ATOM 1347 O3' DT D 14 -4.730 -26.492 39.847 1.00101.64 O ANISOU 1347 O3' DT D 14 13403 14088 11129 -732 -5246 279 O ATOM 1348 C2' DT D 14 -6.616 -26.952 41.280 1.00 88.88 C ANISOU 1348 C2' DT D 14 12565 12358 8845 -373 -5135 202 C ATOM 1349 C1' DT D 14 -7.430 -25.962 40.479 1.00 81.68 C ANISOU 1349 C1' DT D 14 11845 11122 8069 -423 -5018 17 C ATOM 1350 N1 DT D 14 -8.630 -25.400 41.167 1.00 82.02 N ANISOU 1350 N1 DT D 14 12557 10925 7683 -276 -4945 -210 N ATOM 1351 C2 DT D 14 -8.893 -24.058 41.021 1.00 83.49 C ANISOU 1351 C2 DT D 14 13099 10788 7835 -429 -5027 -484 C ATOM 1352 O2 DT D 14 -8.201 -23.312 40.349 1.00 80.83 O ANISOU 1352 O2 DT D 14 12540 10353 7820 -701 -5178 -518 O ATOM 1353 N3 DT D 14 -10.001 -23.614 41.682 1.00 86.86 N ANISOU 1353 N3 DT D 14 14145 11011 7848 -234 -4876 -711 N ATOM 1354 C4 DT D 14 -10.863 -24.348 42.465 1.00 90.62 C ANISOU 1354 C4 DT D 14 14895 11595 7940 90 -4632 -676 C ATOM 1355 O4 DT D 14 -11.840 -23.835 43.015 1.00 92.79 O ANISOU 1355 O4 DT D 14 15698 11691 7866 270 -4429 -894 O ATOM 1356 C5 DT D 14 -10.537 -25.757 42.588 1.00 81.85 C ANISOU 1356 C5 DT D 14 13379 10824 6896 211 -4586 -353 C ATOM 1357 C7 DT D 14 -11.401 -26.661 43.414 1.00 75.86 C ANISOU 1357 C7 DT D 14 12837 10208 5779 541 -4309 -247 C ATOM 1358 C6 DT D 14 -9.442 -26.211 41.940 1.00 81.09 C ANISOU 1358 C6 DT D 14 12692 10906 7211 26 -4753 -145 C ATOM 1359 P DA D 15 -3.172 -26.878 39.840 1.00 93.79 P ANISOU 1359 P DA D 15 11988 13368 10282 -839 -5389 399 P ATOM 1360 OP1 DA D 15 -3.010 -27.862 38.743 1.00 93.19 O ANISOU 1360 OP1 DA D 15 11396 13430 10581 -660 -5057 559 O ATOM 1361 OP2 DA D 15 -2.753 -27.178 41.232 1.00 90.00 O ANISOU 1361 OP2 DA D 15 11737 13060 9398 -827 -5660 414 O ATOM 1362 O5' DA D 15 -2.446 -25.514 39.426 1.00 90.49 O ANISOU 1362 O5' DA D 15 11570 12797 10014 -1175 -5579 258 O ATOM 1363 C5' DA D 15 -2.897 -24.784 38.286 1.00 86.41 C ANISOU 1363 C5' DA D 15 10970 12060 9801 -1255 -5398 200 C ATOM 1364 C4' DA D 15 -2.941 -23.291 38.577 1.00 89.34 C ANISOU 1364 C4' DA D 15 11740 12138 10067 -1531 -5655 -10 C ATOM 1365 O4' DA D 15 -4.160 -22.967 39.297 1.00 91.02 O ANISOU 1365 O4' DA D 15 12524 12113 9948 -1438 -5685 -187 O ATOM 1366 C3' DA D 15 -1.790 -22.757 39.430 1.00 94.05 C ANISOU 1366 C3' DA D 15 12443 12812 10482 -1775 -6026 -77 C ATOM 1367 O3' DA D 15 -1.402 -21.482 38.952 1.00 88.63 O ANISOU 1367 O3' DA D 15 11797 11908 9970 -2055 -6149 -178 O ATOM 1368 C2' DA D 15 -2.401 -22.678 40.831 1.00 97.65 C ANISOU 1368 C2' DA D 15 13467 13196 10438 -1726 -6215 -243 C ATOM 1369 C1' DA D 15 -3.849 -22.327 40.519 1.00 97.15 C ANISOU 1369 C1' DA D 15 13747 12821 10344 -1590 -6009 -372 C ATOM 1370 N9 DA D 15 -4.801 -22.785 41.534 1.00 99.30 N ANISOU 1370 N9 DA D 15 14469 13087 10174 -1355 -5964 -459 N ATOM 1371 C8 DA D 15 -4.964 -24.062 42.003 1.00 96.07 C ANISOU 1371 C8 DA D 15 13942 12955 9604 -1103 -5853 -280 C ATOM 1372 N7 DA D 15 -5.908 -24.178 42.911 1.00 94.86 N ANISOU 1372 N7 DA D 15 14277 12742 9023 -912 -5794 -394 N ATOM 1373 C5 DA D 15 -6.400 -22.888 43.046 1.00 96.87 C ANISOU 1373 C5 DA D 15 15017 12646 9143 -1030 -5856 -700 C ATOM 1374 C6 DA D 15 -7.419 -22.332 43.854 1.00 94.95 C ANISOU 1374 C6 DA D 15 15421 12183 8473 -894 -5777 -970 C ATOM 1375 N6 DA D 15 -8.156 -23.042 44.716 1.00 93.08 N ANISOU 1375 N6 DA D 15 15444 12084 7841 -608 -5609 -949 N ATOM 1376 N1 DA D 15 -7.654 -21.010 43.736 1.00 95.89 N ANISOU 1376 N1 DA D 15 15898 11940 8596 -1045 -5836 -1255 N ATOM 1377 C2 DA D 15 -6.919 -20.291 42.879 1.00 99.61 C ANISOU 1377 C2 DA D 15 16095 12280 9473 -1335 -5989 -1243 C ATOM 1378 N3 DA D 15 -5.945 -20.697 42.066 1.00102.97 N ANISOU 1378 N3 DA D 15 15906 12910 10309 -1488 -6062 -987 N ATOM 1379 C4 DA D 15 -5.730 -22.018 42.202 1.00101.44 C ANISOU 1379 C4 DA D 15 15374 13073 10096 -1313 -5979 -736 C ATOM 1380 P DA D 16 -0.099 -20.748 39.533 1.00124.41 P ANISOU 1380 P DA D 16 16356 16501 14413 -2361 -6517 -239 P ATOM 1381 OP1 DA D 16 0.747 -20.407 38.369 1.00124.87 O ANISOU 1381 OP1 DA D 16 15970 16609 14867 -2489 -6425 -112 O ATOM 1382 OP2 DA D 16 0.468 -21.540 40.651 1.00125.11 O ANISOU 1382 OP2 DA D 16 16463 16888 14186 -2295 -6700 -201 O ATOM 1383 O5' DA D 16 -0.691 -19.401 40.144 1.00109.62 O ANISOU 1383 O5' DA D 16 15092 14234 12324 -2560 -6734 -530 O ATOM 1384 C5' DA D 16 -2.074 -19.120 40.000 1.00 95.93 C ANISOU 1384 C5' DA D 16 13718 12194 10537 -2418 -6559 -666 C ATOM 1385 C4' DA D 16 -2.423 -17.770 40.598 1.00100.32 C ANISOU 1385 C4' DA D 16 14862 12363 10891 -2608 -6765 -978 C ATOM 1386 O4' DA D 16 -3.454 -17.939 41.597 1.00101.28 O ANISOU 1386 O4' DA D 16 15531 12378 10574 -2402 -6727 -1187 O ATOM 1387 C3' DA D 16 -1.287 -17.055 41.316 1.00109.24 C ANISOU 1387 C3' DA D 16 16083 13528 11894 -2920 -7130 -1085 C ATOM 1388 O3' DA D 16 -1.525 -15.653 41.280 1.00110.01 O ANISOU 1388 O3' DA D 16 16563 13207 12027 -3131 -7244 -1325 O ATOM 1389 C2' DA D 16 -1.389 -17.618 42.734 1.00114.15 C ANISOU 1389 C2' DA D 16 17025 14335 12011 -2807 -7263 -1204 C ATOM 1390 C1' DA D 16 -2.899 -17.807 42.897 1.00114.24 C ANISOU 1390 C1' DA D 16 17448 14136 11821 -2511 -7008 -1337 C ATOM 1391 N9 DA D 16 -3.272 -18.990 43.669 1.00115.65 N ANISOU 1391 N9 DA D 16 17669 14604 11667 -2233 -6918 -1257 N ATOM 1392 C8 DA D 16 -2.692 -20.232 43.627 1.00110.01 C ANISOU 1392 C8 DA D 16 16486 14297 11015 -2118 -6884 -968 C ATOM 1393 N7 DA D 16 -3.255 -21.107 44.431 1.00106.42 N ANISOU 1393 N7 DA D 16 16200 14021 10213 -1859 -6795 -938 N ATOM 1394 C5 DA D 16 -4.278 -20.391 45.036 1.00110.79 C ANISOU 1394 C5 DA D 16 17375 14282 10438 -1788 -6745 -1236 C ATOM 1395 C6 DA D 16 -5.254 -20.740 45.995 1.00106.90 C ANISOU 1395 C6 DA D 16 17322 13814 9483 -1519 -6605 -1351 C ATOM 1396 N6 DA D 16 -5.366 -21.960 46.536 1.00106.05 N ANISOU 1396 N6 DA D 16 17082 14046 9166 -1288 -6517 -1144 N ATOM 1397 N1 DA D 16 -6.118 -19.780 46.378 1.00108.91 N ANISOU 1397 N1 DA D 16 18149 13730 9502 -1479 -6528 -1679 N ATOM 1398 C2 DA D 16 -6.020 -18.557 45.840 1.00111.27 C ANISOU 1398 C2 DA D 16 18584 13667 10027 -1701 -6609 -1873 C ATOM 1399 N3 DA D 16 -5.154 -18.110 44.936 1.00113.05 N ANISOU 1399 N3 DA D 16 18436 13826 10691 -1982 -6762 -1771 N ATOM 1400 C4 DA D 16 -4.301 -19.085 44.573 1.00114.89 C ANISOU 1400 C4 DA D 16 18092 14426 11134 -2008 -6816 -1448 C ATOM 1401 P DC D 17 -0.604 -14.633 42.111 1.00133.72 P ANISOU 1401 P DC D 17 19817 16129 14862 -3478 -7629 -1532 P ATOM 1402 OP1 DC D 17 -0.603 -13.356 41.363 1.00129.81 O ANISOU 1402 OP1 DC D 17 19395 15252 14675 -3701 -7657 -1608 O ATOM 1403 OP2 DC D 17 0.680 -15.300 42.424 1.00136.70 O ANISOU 1403 OP2 DC D 17 19788 16948 15204 -3577 -7813 -1346 O ATOM 1404 O5' DC D 17 -1.402 -14.437 43.484 1.00128.43 O ANISOU 1404 O5' DC D 17 19823 15315 13660 -3368 -7695 -1881 O ATOM 1405 C5' DC D 17 -2.790 -14.117 43.457 1.00122.22 C ANISOU 1405 C5' DC D 17 19488 14178 12771 -3145 -7452 -2079 C ATOM 1406 C4' DC D 17 -3.322 -13.895 44.860 1.00124.23 C ANISOU 1406 C4' DC D 17 20356 14361 12483 -3047 -7514 -2420 C ATOM 1407 O4' DC D 17 -3.691 -15.166 45.458 1.00122.50 O ANISOU 1407 O4' DC D 17 20097 14495 11953 -2752 -7389 -2305 O ATOM 1408 C3' DC D 17 -2.336 -13.244 45.830 1.00131.86 C ANISOU 1408 C3' DC D 17 21482 15392 13226 -3358 -7889 -2619 C ATOM 1409 O3' DC D 17 -3.016 -12.288 46.626 1.00142.62 O ANISOU 1409 O3' DC D 17 23487 16415 14287 -3344 -7891 -3032 O ATOM 1410 C2' DC D 17 -1.853 -14.424 46.671 1.00132.88 C ANISOU 1410 C2' DC D 17 21417 16037 13036 -3255 -7985 -2475 C ATOM 1411 C1' DC D 17 -3.120 -15.253 46.742 1.00128.92 C ANISOU 1411 C1' DC D 17 21080 15554 12350 -2840 -7640 -2438 C ATOM 1412 N1 DC D 17 -2.886 -16.684 47.062 1.00126.58 N ANISOU 1412 N1 DC D 17 20448 15738 11909 -2648 -7601 -2158 N ATOM 1413 C2 DC D 17 -3.748 -17.337 47.947 1.00125.55 C ANISOU 1413 C2 DC D 17 20619 15744 11340 -2339 -7438 -2222 C ATOM 1414 O2 DC D 17 -4.689 -16.706 48.446 1.00127.35 O ANISOU 1414 O2 DC D 17 21384 15702 11300 -2217 -7309 -2522 O ATOM 1415 N3 DC D 17 -3.529 -18.646 48.232 1.00123.73 N ANISOU 1415 N3 DC D 17 20072 15943 10998 -2163 -7402 -1942 N ATOM 1416 C4 DC D 17 -2.503 -19.291 47.669 1.00122.04 C ANISOU 1416 C4 DC D 17 19275 16004 11092 -2266 -7507 -1633 C ATOM 1417 N4 DC D 17 -2.331 -20.582 47.978 1.00120.55 N ANISOU 1417 N4 DC D 17 18795 16213 10795 -2064 -7451 -1364 N ATOM 1418 C5 DC D 17 -1.612 -18.639 46.763 1.00122.02 C ANISOU 1418 C5 DC D 17 18956 15883 11525 -2562 -7648 -1579 C ATOM 1419 C6 DC D 17 -1.838 -17.348 46.491 1.00124.90 C ANISOU 1419 C6 DC D 17 19629 15833 11993 -2753 -7698 -1834 C ATOM 1420 P DG D 18 -2.212 -11.069 47.296 1.00154.48 P ANISOU 1420 P DG D 18 25251 17753 15693 -3724 -8243 -3336 P ATOM 1421 OP1 DG D 18 -2.872 -9.823 46.843 1.00152.23 O ANISOU 1421 OP1 DG D 18 25328 16905 15606 -3766 -8128 -3576 O ATOM 1422 OP2 DG D 18 -0.767 -11.276 47.040 1.00154.30 O ANISOU 1422 OP2 DG D 18 24707 18043 15877 -4033 -8538 -3089 O ATOM 1423 O5' DG D 18 -2.457 -11.270 48.869 1.00156.06 O ANISOU 1423 O5' DG D 18 25878 18152 15268 -3607 -8321 -3628 O ATOM 1424 C5' DG D 18 -3.787 -11.331 49.384 1.00154.67 C ANISOU 1424 C5' DG D 18 26173 17826 14769 -3248 -8018 -3843 C ATOM 1425 C4' DG D 18 -3.821 -12.030 50.735 1.00156.66 C ANISOU 1425 C4' DG D 18 26581 18489 14453 -3103 -8077 -3936 C ATOM 1426 O4' DG D 18 -3.523 -13.443 50.565 1.00153.18 O ANISOU 1426 O4' DG D 18 25666 18512 14022 -2962 -8041 -3533 O ATOM 1427 C3' DG D 18 -2.819 -11.502 51.766 1.00163.21 C ANISOU 1427 C3' DG D 18 27516 19491 15006 -3428 -8474 -4174 C ATOM 1428 O3' DG D 18 -3.450 -11.362 53.034 1.00169.80 O ANISOU 1428 O3' DG D 18 28830 20394 15292 -3259 -8418 -4512 O ATOM 1429 C2' DG D 18 -1.741 -12.584 51.795 1.00161.37 C ANISOU 1429 C2' DG D 18 26724 19801 14790 -3522 -8682 -3807 C ATOM 1430 C1' DG D 18 -2.559 -13.831 51.514 1.00155.88 C ANISOU 1430 C1' DG D 18 25868 19296 14065 -3118 -8349 -3516 C ATOM 1431 N9 DG D 18 -1.777 -14.939 50.968 1.00151.16 N ANISOU 1431 N9 DG D 18 24649 19081 13702 -3123 -8405 -3074 N ATOM 1432 C8 DG D 18 -0.699 -14.860 50.115 1.00148.14 C ANISOU 1432 C8 DG D 18 23789 18743 13753 -3388 -8580 -2849 C ATOM 1433 N7 DG D 18 -0.200 -16.025 49.799 1.00143.88 N ANISOU 1433 N7 DG D 18 22741 18589 13339 -3283 -8552 -2474 N ATOM 1434 C5 DG D 18 -0.996 -16.934 50.488 1.00142.45 C ANISOU 1434 C5 DG D 18 22713 18621 12790 -2945 -8366 -2437 C ATOM 1435 C6 DG D 18 -0.937 -18.350 50.537 1.00139.02 C ANISOU 1435 C6 DG D 18 21915 18596 12312 -2696 -8253 -2093 C ATOM 1436 O6 DG D 18 -0.140 -19.106 49.959 1.00136.50 O ANISOU 1436 O6 DG D 18 21053 18532 12281 -2709 -8286 -1763 O ATOM 1437 N1 DG D 18 -1.936 -18.879 51.359 1.00138.92 N ANISOU 1437 N1 DG D 18 22225 18686 11873 -2389 -8063 -2155 N ATOM 1438 C2 DG D 18 -2.869 -18.129 52.044 1.00141.76 C ANISOU 1438 C2 DG D 18 23177 18800 11885 -2314 -7970 -2518 C ATOM 1439 N2 DG D 18 -3.753 -18.806 52.785 1.00141.33 N ANISOU 1439 N2 DG D 18 23337 18923 11439 -1994 -7754 -2505 N ATOM 1440 N3 DG D 18 -2.932 -16.807 52.003 1.00145.02 N ANISOU 1440 N3 DG D 18 23938 18821 12342 -2525 -8061 -2865 N ATOM 1441 C4 DG D 18 -1.970 -16.279 51.211 1.00145.17 C ANISOU 1441 C4 DG D 18 23658 18721 12781 -2844 -8269 -2797 C TER 1442 DG D 18 ATOM 1443 O5' DC E 19 -3.015 -28.497 54.602 1.00172.21 O ANISOU 1443 O5' DC E 19 27667 25112 12654 501 -7741 1777 O ATOM 1444 C5' DC E 19 -4.109 -27.709 54.139 1.00171.41 C ANISOU 1444 C5' DC E 19 27720 24848 12561 474 -7505 1423 C ATOM 1445 C4' DC E 19 -4.201 -26.409 54.919 1.00179.62 C ANISOU 1445 C4' DC E 19 29028 26174 13045 574 -7597 840 C ATOM 1446 O4' DC E 19 -3.169 -25.489 54.461 1.00179.53 O ANISOU 1446 O4' DC E 19 28813 25837 13562 382 -7929 319 O ATOM 1447 C3' DC E 19 -5.520 -25.649 54.768 1.00177.24 C ANISOU 1447 C3' DC E 19 28987 25854 12503 661 -7265 547 C ATOM 1448 O3' DC E 19 -5.818 -24.970 55.998 1.00186.22 O ANISOU 1448 O3' DC E 19 30513 27473 12769 897 -7241 299 O ATOM 1449 C2' DC E 19 -5.191 -24.673 53.646 1.00168.25 C ANISOU 1449 C2' DC E 19 27617 24164 12147 428 -7385 -11 C ATOM 1450 C1' DC E 19 -3.781 -24.286 54.042 1.00173.07 C ANISOU 1450 C1' DC E 19 28098 24795 12865 343 -7819 -237 C ATOM 1451 N1 DC E 19 -2.971 -23.674 52.944 1.00160.93 N ANISOU 1451 N1 DC E 19 26204 22720 12221 99 -7996 -537 N ATOM 1452 C2 DC E 19 -3.040 -22.292 52.730 1.00154.12 C ANISOU 1452 C2 DC E 19 25385 21652 11523 45 -8040 -1120 C ATOM 1453 O2 DC E 19 -3.787 -21.614 53.443 1.00155.10 O ANISOU 1453 O2 DC E 19 25865 22013 11051 203 -7938 -1424 O ATOM 1454 N3 DC E 19 -2.289 -21.739 51.744 1.00146.83 N ANISOU 1454 N3 DC E 19 24116 20269 11404 -151 -8167 -1298 N ATOM 1455 C4 DC E 19 -1.497 -22.514 50.998 1.00144.03 C ANISOU 1455 C4 DC E 19 23415 19677 11633 -272 -8233 -943 C ATOM 1456 N4 DC E 19 -0.774 -21.930 50.039 1.00138.48 N ANISOU 1456 N4 DC E 19 22391 18556 11669 -421 -8315 -1076 N ATOM 1457 C5 DC E 19 -1.414 -23.924 51.203 1.00146.33 C ANISOU 1457 C5 DC E 19 23685 20146 11768 -218 -8196 -401 C ATOM 1458 C6 DC E 19 -2.154 -24.455 52.181 1.00154.01 C ANISOU 1458 C6 DC E 19 24974 21562 11980 -42 -8088 -206 C ATOM 1459 P DG E 20 -6.878 -23.761 56.056 1.00176.16 P ANISOU 1459 P DG E 20 29565 26186 11182 1039 -6972 -230 P ATOM 1460 OP1 DG E 20 -6.178 -22.529 55.628 1.00174.48 O ANISOU 1460 OP1 DG E 20 29246 25598 11451 859 -7276 -925 O ATOM 1461 OP2 DG E 20 -7.519 -23.799 57.389 1.00185.75 O ANISOU 1461 OP2 DG E 20 31218 27992 11366 1388 -6745 -73 O ATOM 1462 O5' DG E 20 -7.987 -24.150 54.971 1.00160.58 O ANISOU 1462 O5' DG E 20 27482 23917 9613 987 -6576 30 O ATOM 1463 C5' DG E 20 -9.367 -23.919 55.241 1.00163.51 C ANISOU 1463 C5' DG E 20 28171 24507 9447 1245 -6101 103 C ATOM 1464 C4' DG E 20 -9.673 -22.433 55.365 1.00165.82 C ANISOU 1464 C4' DG E 20 28694 24731 9579 1355 -6050 -644 C ATOM 1465 O4' DG E 20 -8.609 -21.653 54.766 1.00162.72 O ANISOU 1465 O4' DG E 20 28040 23910 9878 1071 -6477 -1187 O ATOM 1466 C3' DG E 20 -10.925 -21.981 54.645 1.00162.38 C ANISOU 1466 C3' DG E 20 28321 24116 9259 1433 -5614 -743 C ATOM 1467 O3' DG E 20 -11.398 -20.780 55.235 1.00166.84 O ANISOU 1467 O3' DG E 20 29230 24812 9349 1702 -5441 -1280 O ATOM 1468 C2' DG E 20 -10.405 -21.752 53.225 1.00151.70 C ANISOU 1468 C2' DG E 20 26537 22156 8947 1045 -5863 -998 C ATOM 1469 C1' DG E 20 -9.010 -21.181 53.489 1.00156.23 C ANISOU 1469 C1' DG E 20 26980 22610 9769 894 -6353 -1412 C ATOM 1470 N9 DG E 20 -7.991 -21.594 52.519 1.00150.96 N ANISOU 1470 N9 DG E 20 25842 21535 9980 563 -6656 -1312 N ATOM 1471 C8 DG E 20 -7.608 -22.880 52.220 1.00146.64 C ANISOU 1471 C8 DG E 20 25074 20954 9687 447 -6732 -754 C ATOM 1472 N7 DG E 20 -6.654 -22.948 51.330 1.00139.91 N ANISOU 1472 N7 DG E 20 23827 19699 9634 202 -6966 -797 N ATOM 1473 C5 DG E 20 -6.376 -21.621 51.024 1.00140.54 C ANISOU 1473 C5 DG E 20 23836 19547 10015 138 -7052 -1372 C ATOM 1474 C6 DG E 20 -5.430 -21.070 50.123 1.00133.71 C ANISOU 1474 C6 DG E 20 22589 18257 9958 -69 -7240 -1582 C ATOM 1475 O6 DG E 20 -4.622 -21.668 49.395 1.00129.52 O ANISOU 1475 O6 DG E 20 21718 17474 10018 -217 -7356 -1323 O ATOM 1476 N1 DG E 20 -5.477 -19.677 50.116 1.00134.88 N ANISOU 1476 N1 DG E 20 22792 18277 10181 -64 -7259 -2110 N ATOM 1477 C2 DG E 20 -6.328 -18.912 50.881 1.00140.96 C ANISOU 1477 C2 DG E 20 23960 19273 10326 128 -7117 -2449 C ATOM 1478 N2 DG E 20 -6.226 -17.583 50.738 1.00140.60 N ANISOU 1478 N2 DG E 20 23916 19006 10499 105 -7169 -2940 N ATOM 1479 N3 DG E 20 -7.218 -19.415 51.730 1.00147.43 N ANISOU 1479 N3 DG E 20 25159 20505 10351 358 -6908 -2279 N ATOM 1480 C4 DG E 20 -7.187 -20.772 51.751 1.00147.17 C ANISOU 1480 C4 DG E 20 25055 20628 10234 343 -6886 -1713 C ATOM 1481 P DT E 21 -12.705 -20.052 54.655 1.00176.00 P ANISOU 1481 P DT E 21 30498 25844 10529 1868 -4942 -1482 P ATOM 1482 OP1 DT E 21 -13.338 -19.313 55.770 1.00183.66 O ANISOU 1482 OP1 DT E 21 31931 27191 10661 2326 -4619 -1720 O ATOM 1483 OP2 DT E 21 -13.483 -21.051 53.889 1.00169.43 O ANISOU 1483 OP2 DT E 21 29488 24967 9920 1796 -4637 -847 O ATOM 1484 O5' DT E 21 -12.117 -19.002 53.609 1.00160.20 O ANISOU 1484 O5' DT E 21 28210 23259 9401 1545 -5256 -2134 O ATOM 1485 C5' DT E 21 -12.990 -18.293 52.761 1.00156.16 C ANISOU 1485 C5' DT E 21 27643 22490 9201 1563 -4942 -2381 C ATOM 1486 C4' DT E 21 -12.221 -17.296 51.925 1.00152.48 C ANISOU 1486 C4' DT E 21 26861 21509 9565 1263 -5271 -2931 C ATOM 1487 O4' DT E 21 -10.989 -17.906 51.454 1.00149.47 O ANISOU 1487 O4' DT E 21 26086 20905 9801 913 -5717 -2756 O ATOM 1488 C3' DT E 21 -12.959 -16.809 50.679 1.00149.78 C ANISOU 1488 C3' DT E 21 26280 20822 9807 1163 -5009 -3070 C ATOM 1489 O3' DT E 21 -12.765 -15.415 50.518 1.00152.07 O ANISOU 1489 O3' DT E 21 26543 20839 10397 1155 -5066 -3660 O ATOM 1490 C2' DT E 21 -12.300 -17.602 49.554 1.00142.48 C ANISOU 1490 C2' DT E 21 24857 19571 9707 774 -5270 -2778 C ATOM 1491 C1' DT E 21 -10.876 -17.697 50.066 1.00145.76 C ANISOU 1491 C1' DT E 21 25172 19974 10236 638 -5736 -2826 C ATOM 1492 N1 DT E 21 -10.088 -18.814 49.465 1.00142.79 N ANISOU 1492 N1 DT E 21 24431 19449 10374 380 -5976 -2397 N ATOM 1493 C2 DT E 21 -9.107 -18.515 48.551 1.00137.72 C ANISOU 1493 C2 DT E 21 23341 18408 10578 128 -6203 -2508 C ATOM 1494 O2 DT E 21 -8.841 -17.378 48.202 1.00139.03 O ANISOU 1494 O2 DT E 21 23375 18340 11110 80 -6237 -2902 O ATOM 1495 N3 DT E 21 -8.439 -19.598 48.055 1.00129.55 N ANISOU 1495 N3 DT E 21 22024 17255 9943 -36 -6359 -2094 N ATOM 1496 C4 DT E 21 -8.640 -20.928 48.366 1.00127.55 C ANISOU 1496 C4 DT E 21 21879 17201 9385 -13 -6351 -1592 C ATOM 1497 O4 DT E 21 -7.971 -21.829 47.857 1.00120.73 O ANISOU 1497 O4 DT E 21 20751 16163 8956 -159 -6496 -1255 O ATOM 1498 C5 DT E 21 -9.688 -21.180 49.332 1.00134.68 C ANISOU 1498 C5 DT E 21 23233 18525 9412 227 -6122 -1441 C ATOM 1499 C7 DT E 21 -10.004 -22.585 49.750 1.00133.76 C ANISOU 1499 C7 DT E 21 23251 18655 8916 278 -6061 -789 C ATOM 1500 C6 DT E 21 -10.355 -20.122 49.830 1.00141.68 C ANISOU 1500 C6 DT E 21 24411 19568 9854 431 -5924 -1845 C ATOM 1501 P DT E 22 -13.863 -14.540 49.739 1.00147.19 P ANISOU 1501 P DT E 22 25885 20029 10010 1258 -4639 -3914 P ATOM 1502 OP1 DT E 22 -13.854 -13.184 50.331 1.00149.95 O ANISOU 1502 OP1 DT E 22 26492 20313 10168 1449 -4623 -4466 O ATOM 1503 OP2 DT E 22 -15.116 -15.331 49.697 1.00145.32 O ANISOU 1503 OP2 DT E 22 25821 20088 9308 1475 -4164 -3484 O ATOM 1504 O5' DT E 22 -13.305 -14.461 48.243 1.00129.73 O ANISOU 1504 O5' DT E 22 23066 17336 8891 849 -4835 -3914 O ATOM 1505 C5' DT E 22 -12.111 -13.740 47.960 1.00129.82 C ANISOU 1505 C5' DT E 22 22782 17027 9516 621 -5204 -4172 C ATOM 1506 C4' DT E 22 -11.595 -14.107 46.585 1.00122.40 C ANISOU 1506 C4' DT E 22 21256 15761 9490 308 -5300 -3937 C ATOM 1507 O4' DT E 22 -10.936 -15.388 46.659 1.00121.21 O ANISOU 1507 O4' DT E 22 21000 15704 9349 181 -5530 -3513 O ATOM 1508 C3' DT E 22 -12.690 -14.286 45.532 1.00122.99 C ANISOU 1508 C3' DT E 22 21144 15745 9840 296 -4939 -3818 C ATOM 1509 O3' DT E 22 -12.863 -13.109 44.666 1.00125.78 O ANISOU 1509 O3' DT E 22 21218 15807 10767 252 -4784 -4111 O ATOM 1510 C2' DT E 22 -12.286 -15.541 44.750 1.00114.56 C ANISOU 1510 C2' DT E 22 19733 14587 9207 73 -5078 -3359 C ATOM 1511 C1' DT E 22 -10.954 -15.951 45.378 1.00115.95 C ANISOU 1511 C1' DT E 22 19898 14805 9355 -7 -5463 -3240 C ATOM 1512 N1 DT E 22 -10.783 -17.436 45.474 1.00116.53 N ANISOU 1512 N1 DT E 22 19980 14999 9296 -74 -5580 -2763 N ATOM 1513 C2 DT E 22 -9.714 -18.025 44.841 1.00113.72 C ANISOU 1513 C2 DT E 22 19249 14431 9526 -252 -5796 -2516 C ATOM 1514 O2 DT E 22 -8.870 -17.394 44.230 1.00111.49 O ANISOU 1514 O2 DT E 22 18638 13904 9818 -338 -5884 -2633 O ATOM 1515 N3 DT E 22 -9.658 -19.388 44.960 1.00111.80 N ANISOU 1515 N3 DT E 22 19056 14276 9148 -298 -5884 -2080 N ATOM 1516 C4 DT E 22 -10.545 -20.212 45.626 1.00112.90 C ANISOU 1516 C4 DT E 22 19559 14696 8641 -206 -5791 -1807 C ATOM 1517 O4 DT E 22 -10.397 -21.433 45.674 1.00109.80 O ANISOU 1517 O4 DT E 22 19173 14333 8214 -274 -5895 -1359 O ATOM 1518 C5 DT E 22 -11.654 -19.535 46.260 1.00118.14 C ANISOU 1518 C5 DT E 22 20611 15616 8662 6 -5527 -2030 C ATOM 1519 C7 DT E 22 -12.686 -20.321 47.014 1.00121.25 C ANISOU 1519 C7 DT E 22 21435 16375 8258 182 -5318 -1640 C ATOM 1520 C6 DT E 22 -11.723 -18.194 46.148 1.00119.16 C ANISOU 1520 C6 DT E 22 20707 15647 8922 72 -5430 -2524 C ATOM 1521 P DA E 23 -11.641 -12.293 43.990 1.00124.86 P ANISOU 1521 P DA E 23 20660 15347 11433 49 -5026 -4211 P ATOM 1522 OP1 DA E 23 -10.787 -11.675 45.025 1.00131.76 O ANISOU 1522 OP1 DA E 23 21789 16236 12037 84 -5339 -4461 O ATOM 1523 OP2 DA E 23 -12.273 -11.414 42.984 1.00119.63 O ANISOU 1523 OP2 DA E 23 19734 14476 11245 47 -4732 -4358 O ATOM 1524 O5' DA E 23 -10.788 -13.371 43.171 1.00107.54 O ANISOU 1524 O5' DA E 23 18041 13056 9764 -157 -5200 -3765 O ATOM 1525 C5' DA E 23 -9.371 -13.224 43.125 1.00106.43 C ANISOU 1525 C5' DA E 23 17687 12767 9985 -270 -5522 -3689 C ATOM 1526 C4' DA E 23 -8.765 -13.815 41.859 1.00 96.86 C ANISOU 1526 C4' DA E 23 15982 11367 9454 -386 -5510 -3318 C ATOM 1527 O4' DA E 23 -8.820 -15.261 41.897 1.00 95.44 O ANISOU 1527 O4' DA E 23 15837 11306 9120 -416 -5544 -2977 O ATOM 1528 C3' DA E 23 -9.399 -13.393 40.542 1.00 91.05 C ANISOU 1528 C3' DA E 23 14895 10472 9228 -388 -5190 -3294 C ATOM 1529 O3' DA E 23 -8.353 -13.197 39.589 1.00 87.41 O ANISOU 1529 O3' DA E 23 14031 9797 9385 -425 -5270 -3090 O ATOM 1530 C2' DA E 23 -10.301 -14.581 40.195 1.00 88.08 C ANISOU 1530 C2' DA E 23 14527 10204 8734 -399 -5017 -3063 C ATOM 1531 C1' DA E 23 -9.527 -15.757 40.780 1.00 91.67 C ANISOU 1531 C1' DA E 23 15105 10742 8982 -441 -5289 -2789 C ATOM 1532 N9 DA E 23 -10.373 -16.846 41.258 1.00 96.44 N ANISOU 1532 N9 DA E 23 15993 11530 9120 -436 -5261 -2631 N ATOM 1533 C8 DA E 23 -11.547 -16.736 41.940 1.00100.12 C ANISOU 1533 C8 DA E 23 16841 12202 8998 -343 -5119 -2784 C ATOM 1534 N7 DA E 23 -12.079 -17.888 42.277 1.00 97.36 N ANISOU 1534 N7 DA E 23 16724 11998 8272 -354 -5149 -2494 N ATOM 1535 C5 DA E 23 -11.190 -18.817 41.779 1.00 93.34 C ANISOU 1535 C5 DA E 23 15948 11334 8181 -479 -5334 -2170 C ATOM 1536 C6 DA E 23 -11.177 -20.221 41.798 1.00 92.18 C ANISOU 1536 C6 DA E 23 15866 11189 7971 -563 -5466 -1754 C ATOM 1537 N6 DA E 23 -12.132 -20.968 42.367 1.00 94.97 N ANISOU 1537 N6 DA E 23 16577 11734 7775 -564 -5450 -1518 N ATOM 1538 N1 DA E 23 -10.140 -20.834 41.204 1.00 93.10 N ANISOU 1538 N1 DA E 23 15693 11095 8586 -630 -5603 -1536 N ATOM 1539 C2 DA E 23 -9.185 -20.097 40.633 1.00 93.67 C ANISOU 1539 C2 DA E 23 15452 11007 9132 -603 -5598 -1675 C ATOM 1540 N3 DA E 23 -9.084 -18.775 40.556 1.00 93.51 N ANISOU 1540 N3 DA E 23 15333 10977 9220 -551 -5507 -2001 N ATOM 1541 C4 DA E 23 -10.128 -18.189 41.153 1.00 94.17 C ANISOU 1541 C4 DA E 23 15689 11236 8855 -502 -5382 -2258 C ATOM 1542 P DT E 24 -8.627 -13.175 38.006 1.00 88.97 P ANISOU 1542 P DT E 24 13788 9855 10160 -395 -4992 -2886 P ATOM 1543 OP1 DT E 24 -7.533 -12.367 37.419 1.00 88.47 O ANISOU 1543 OP1 DT E 24 13456 9586 10570 -360 -5124 -2822 O ATOM 1544 OP2 DT E 24 -10.030 -12.781 37.750 1.00 79.46 O ANISOU 1544 OP2 DT E 24 12616 8714 8860 -371 -4676 -3076 O ATOM 1545 O5' DT E 24 -8.359 -14.688 37.567 1.00 87.37 O ANISOU 1545 O5' DT E 24 13490 9669 10038 -408 -5018 -2507 O ATOM 1546 C5' DT E 24 -7.128 -15.301 37.931 1.00 78.96 C ANISOU 1546 C5' DT E 24 12458 8560 8984 -424 -5307 -2307 C ATOM 1547 C4' DT E 24 -6.937 -16.629 37.227 1.00 75.36 C ANISOU 1547 C4' DT E 24 11878 8042 8714 -403 -5273 -1954 C ATOM 1548 O4' DT E 24 -7.807 -17.631 37.811 1.00 76.69 O ANISOU 1548 O4' DT E 24 12299 8355 8483 -469 -5258 -1914 O ATOM 1549 C3' DT E 24 -7.231 -16.631 35.727 1.00 77.05 C ANISOU 1549 C3' DT E 24 11762 8126 9388 -308 -5015 -1818 C ATOM 1550 O3' DT E 24 -6.234 -17.405 35.068 1.00 72.79 O ANISOU 1550 O3' DT E 24 11095 7423 9138 -227 -5110 -1520 O ATOM 1551 C2' DT E 24 -8.609 -17.294 35.652 1.00 68.68 C ANISOU 1551 C2' DT E 24 10790 7173 8133 -365 -4826 -1837 C ATOM 1552 C1' DT E 24 -8.503 -18.295 36.787 1.00 72.44 C ANISOU 1552 C1' DT E 24 11595 7740 8187 -454 -5055 -1754 C ATOM 1553 N1 DT E 24 -9.802 -18.745 37.337 1.00 79.95 N ANISOU 1553 N1 DT E 24 12796 8837 8746 -537 -4998 -1822 N ATOM 1554 C2 DT E 24 -10.035 -20.090 37.457 1.00 77.86 C ANISOU 1554 C2 DT E 24 12671 8547 8364 -605 -5110 -1563 C ATOM 1555 O2 DT E 24 -9.233 -20.939 37.119 1.00 73.36 O ANISOU 1555 O2 DT E 24 12030 7833 8009 -591 -5228 -1310 O ATOM 1556 N3 DT E 24 -11.248 -20.414 37.993 1.00 78.31 N ANISOU 1556 N3 DT E 24 12992 8733 8029 -688 -5098 -1587 N ATOM 1557 C4 DT E 24 -12.237 -19.554 38.418 1.00 78.64 C ANISOU 1557 C4 DT E 24 13198 8934 7746 -672 -4959 -1864 C ATOM 1558 O4 DT E 24 -13.297 -19.958 38.890 1.00 80.96 O ANISOU 1558 O4 DT E 24 13791 9348 7621 -728 -4965 -1812 O ATOM 1559 C5 DT E 24 -11.935 -18.152 38.269 1.00 78.12 C ANISOU 1559 C5 DT E 24 12975 8870 7837 -579 -4817 -2178 C ATOM 1560 C7 DT E 24 -12.936 -17.122 38.696 1.00 80.40 C ANISOU 1560 C7 DT E 24 13462 9285 7801 -516 -4639 -2520 C ATOM 1561 C6 DT E 24 -10.739 -17.815 37.747 1.00 77.93 C ANISOU 1561 C6 DT E 24 12667 8711 8231 -537 -4861 -2126 C ATOM 1562 P DT E 25 -6.174 -17.505 33.465 1.00 75.59 P ANISOU 1562 P DT E 25 11150 7614 9958 -56 -4912 -1349 P ATOM 1563 OP1 DT E 25 -4.757 -17.338 33.080 1.00 79.18 O ANISOU 1563 OP1 DT E 25 11499 7859 10728 52 -5099 -1190 O ATOM 1564 OP2 DT E 25 -7.228 -16.679 32.840 1.00 60.21 O ANISOU 1564 OP2 DT E 25 9039 5739 8100 -21 -4643 -1511 O ATOM 1565 O5' DT E 25 -6.520 -19.029 33.204 1.00 81.57 O ANISOU 1565 O5' DT E 25 12008 8328 10657 -65 -4895 -1156 O ATOM 1566 C5' DT E 25 -5.736 -20.016 33.833 1.00 63.43 C ANISOU 1566 C5' DT E 25 9897 5967 8236 -118 -5134 -987 C ATOM 1567 C4' DT E 25 -6.369 -21.369 33.669 1.00 67.12 C ANISOU 1567 C4' DT E 25 10492 6379 8631 -158 -5124 -844 C ATOM 1568 O4' DT E 25 -7.628 -21.402 34.377 1.00 68.91 O ANISOU 1568 O4' DT E 25 10870 6787 8527 -308 -5077 -973 O ATOM 1569 C3' DT E 25 -6.680 -21.760 32.222 1.00 58.82 C ANISOU 1569 C3' DT E 25 9271 5159 7920 -9 -4949 -764 C ATOM 1570 O3' DT E 25 -6.205 -23.056 32.008 1.00 59.06 O ANISOU 1570 O3' DT E 25 9431 4982 8027 14 -5093 -566 O ATOM 1571 C2' DT E 25 -8.210 -21.681 32.144 1.00 58.22 C ANISOU 1571 C2' DT E 25 9176 5222 7723 -101 -4775 -887 C ATOM 1572 C1' DT E 25 -8.587 -22.028 33.570 1.00 62.29 C ANISOU 1572 C1' DT E 25 9972 5873 7824 -309 -4944 -915 C ATOM 1573 N1 DT E 25 -9.925 -21.564 34.016 1.00 70.24 N ANISOU 1573 N1 DT E 25 11035 7064 8591 -442 -4830 -1102 N ATOM 1574 C2 DT E 25 -10.771 -22.477 34.585 1.00 70.15 C ANISOU 1574 C2 DT E 25 11254 7062 8339 -610 -4954 -1009 C ATOM 1575 O2 DT E 25 -10.493 -23.646 34.704 1.00 75.18 O ANISOU 1575 O2 DT E 25 12033 7553 8977 -660 -5148 -772 O ATOM 1576 N3 DT E 25 -11.967 -21.978 34.998 1.00 67.16 N ANISOU 1576 N3 DT E 25 10955 6841 7720 -723 -4869 -1179 N ATOM 1577 C4 DT E 25 -12.395 -20.677 34.926 1.00 66.52 C ANISOU 1577 C4 DT E 25 10758 6898 7617 -674 -4658 -1462 C ATOM 1578 O4 DT E 25 -13.497 -20.336 35.341 1.00 68.26 O ANISOU 1578 O4 DT E 25 11116 7235 7584 -764 -4603 -1609 O ATOM 1579 C5 DT E 25 -11.455 -19.749 34.328 1.00 67.61 C ANISOU 1579 C5 DT E 25 10638 7008 8043 -511 -4535 -1544 C ATOM 1580 C7 DT E 25 -11.810 -18.294 34.187 1.00 64.82 C ANISOU 1580 C7 DT E 25 10149 6750 7729 -463 -4331 -1818 C ATOM 1581 C6 DT E 25 -10.270 -20.234 33.913 1.00 62.69 C ANISOU 1581 C6 DT E 25 9934 6240 7647 -408 -4639 -1346 C HETATM 1582 N1 5CM E 26 -11.558 -23.602 30.715 1.00 42.80 N ANISOU 1582 N1 5CM E 26 6125 4729 5407 -461 -937 -1552 N HETATM 1583 C2 5CM E 26 -12.703 -23.713 31.608 1.00 35.79 C ANISOU 1583 C2 5CM E 26 5440 3840 4319 -69 -937 -1520 C HETATM 1584 N3 5CM E 26 -13.490 -22.537 31.927 1.00 43.34 N ANISOU 1584 N3 5CM E 26 6820 4494 5154 21 -939 -1648 N HETATM 1585 C4 5CM E 26 -13.163 -21.287 31.372 1.00 43.16 C ANISOU 1585 C4 5CM E 26 7068 4099 5230 -287 -951 -1781 C HETATM 1586 C5 5CM E 26 -12.008 -21.158 30.478 1.00 46.69 C ANISOU 1586 C5 5CM E 26 7336 4513 5889 -754 -954 -1783 C HETATM 1587 C5A 5CM E 26 -11.655 -19.801 29.904 1.00 39.30 C ANISOU 1587 C5A 5CM E 26 6583 3248 5100 -1079 -864 -1809 C HETATM 1588 C6 5CM E 26 -11.201 -22.345 30.153 1.00 38.87 C ANISOU 1588 C6 5CM E 26 5854 3917 4999 -826 -934 -1670 C HETATM 1589 O2 5CM E 26 -12.997 -24.793 32.087 1.00 39.99 O ANISOU 1589 O2 5CM E 26 5792 4617 4787 197 -913 -1373 O HETATM 1590 N4 5CM E 26 -13.970 -20.178 31.718 1.00 51.62 N ANISOU 1590 N4 5CM E 26 8468 4923 6221 -123 -869 -1815 N HETATM 1591 C1' 5CM E 26 -10.841 -24.828 30.459 1.00 47.31 C ANISOU 1591 C1' 5CM E 26 6278 5618 6080 -433 -910 -1439 C HETATM 1592 C2' 5CM E 26 -9.945 -24.775 29.180 1.00 40.08 C ANISOU 1592 C2' 5CM E 26 5155 4704 5368 -769 -787 -1411 C HETATM 1593 C3' 5CM E 26 -9.080 -25.993 29.423 1.00 45.40 C ANISOU 1593 C3' 5CM E 26 5392 5764 6095 -631 -825 -1374 C HETATM 1594 C4' 5CM E 26 -8.875 -26.001 30.746 1.00 49.33 C ANISOU 1594 C4' 5CM E 26 5851 6449 6443 -502 -1054 -1474 C HETATM 1595 O4' 5CM E 26 -10.004 -25.070 31.407 1.00 50.93 O ANISOU 1595 O4' 5CM E 26 6523 6369 6460 -424 -1105 -1554 O HETATM 1596 O3' 5CM E 26 -9.943 -27.144 29.070 1.00 39.56 O ANISOU 1596 O3' 5CM E 26 4679 4980 5373 -300 -679 -1178 O HETATM 1597 C5' 5CM E 26 -7.558 -25.437 31.144 1.00 43.10 C ANISOU 1597 C5' 5CM E 26 4794 5907 5676 -817 -1259 -1682 C HETATM 1598 O5' 5CM E 26 -7.125 -24.503 30.178 1.00 45.91 O ANISOU 1598 O5' 5CM E 26 5175 6075 6194 -1274 -1149 -1748 O HETATM 1599 P 5CM E 26 -5.883 -23.577 30.531 1.00 51.79 P ANISOU 1599 P 5CM E 26 5698 6977 7003 -1774 -1357 -1994 P HETATM 1600 OP1 5CM E 26 -4.618 -24.401 30.585 1.00 56.60 O ANISOU 1600 OP1 5CM E 26 5661 8141 7703 -1767 -1430 -1984 O HETATM 1601 OP2 5CM E 26 -5.788 -22.424 29.560 1.00 58.96 O ANISOU 1601 OP2 5CM E 26 6832 7507 8063 -2252 -1189 -1983 O ATOM 1602 P DG E 27 -9.324 -28.560 28.622 1.00 40.20 P ANISOU 1602 P DG E 27 4431 5261 5582 -119 -582 -1083 P ATOM 1603 OP1 DG E 27 -8.133 -28.836 29.450 1.00 43.89 O ANISOU 1603 OP1 DG E 27 4556 6077 6043 -60 -753 -1149 O ATOM 1604 OP2 DG E 27 -9.187 -28.629 27.156 1.00 35.48 O ANISOU 1604 OP2 DG E 27 3808 4581 5091 -272 -366 -1071 O ATOM 1605 O5' DG E 27 -10.508 -29.567 28.946 1.00 34.20 O ANISOU 1605 O5' DG E 27 3835 4365 4794 214 -531 -909 O ATOM 1606 C5' DG E 27 -10.662 -30.082 30.254 1.00 32.45 C ANISOU 1606 C5' DG E 27 3604 4266 4460 481 -656 -819 C ATOM 1607 C4' DG E 27 -12.094 -30.534 30.479 1.00 32.83 C ANISOU 1607 C4' DG E 27 3878 4128 4470 649 -561 -644 C ATOM 1608 O4' DG E 27 -12.952 -29.375 30.699 1.00 32.09 O ANISOU 1608 O4' DG E 27 4020 3935 4238 568 -577 -707 O ATOM 1609 C3' DG E 27 -12.732 -31.299 29.336 1.00 29.36 C ANISOU 1609 C3' DG E 27 3475 3475 4206 624 -388 -564 C ATOM 1610 O3' DG E 27 -13.661 -32.225 29.887 1.00 34.50 O ANISOU 1610 O3' DG E 27 4195 4043 4872 806 -332 -357 O ATOM 1611 C2' DG E 27 -13.450 -30.184 28.545 1.00 25.63 C ANISOU 1611 C2' DG E 27 3178 2867 3694 417 -347 -643 C ATOM 1612 C1' DG E 27 -13.916 -29.266 29.672 1.00 31.82 C ANISOU 1612 C1' DG E 27 4105 3692 4291 489 -443 -657 C ATOM 1613 N9 DG E 27 -14.007 -27.843 29.340 1.00 39.80 N ANISOU 1613 N9 DG E 27 5302 4584 5236 320 -472 -793 N ATOM 1614 C8 DG E 27 -13.082 -27.080 28.660 1.00 42.42 C ANISOU 1614 C8 DG E 27 5629 4868 5621 47 -490 -926 C ATOM 1615 N7 DG E 27 -13.414 -25.812 28.576 1.00 41.12 N ANISOU 1615 N7 DG E 27 5725 4510 5390 -58 -511 -1000 N ATOM 1616 C5 DG E 27 -14.617 -25.725 29.270 1.00 34.44 C ANISOU 1616 C5 DG E 27 5038 3624 4424 215 -510 -938 C ATOM 1617 C6 DG E 27 -15.453 -24.611 29.520 1.00 38.57 C ANISOU 1617 C6 DG E 27 5866 3954 4836 324 -514 -983 C ATOM 1618 O6 DG E 27 -15.299 -23.424 29.184 1.00 46.17 O ANISOU 1618 O6 DG E 27 7085 4661 5796 182 -535 -1083 O ATOM 1619 N1 DG E 27 -16.565 -24.966 30.253 1.00 34.92 N ANISOU 1619 N1 DG E 27 5407 3600 4262 646 -467 -884 N ATOM 1620 C2 DG E 27 -16.854 -26.218 30.696 1.00 34.83 C ANISOU 1620 C2 DG E 27 5164 3812 4259 783 -418 -729 C ATOM 1621 N2 DG E 27 -17.996 -26.341 31.393 1.00 32.17 N ANISOU 1621 N2 DG E 27 4841 3580 3803 1057 -333 -614 N ATOM 1622 N3 DG E 27 -16.086 -27.281 30.477 1.00 40.53 N ANISOU 1622 N3 DG E 27 5663 4636 5101 675 -427 -674 N ATOM 1623 C4 DG E 27 -14.986 -26.960 29.762 1.00 37.84 C ANISOU 1623 C4 DG E 27 5288 4233 4856 421 -478 -801 C HETATM 1624 N1 5CM E 28 -17.937 -28.714 27.863 1.00 36.69 N ANISOU 1624 N1 5CM E 28 4992 4014 4934 557 -231 -394 N HETATM 1625 C2 5CM E 28 -18.590 -27.431 27.988 1.00 38.77 C ANISOU 1625 C2 5CM E 28 5431 4230 5070 668 -247 -414 C HETATM 1626 N3 5CM E 28 -17.943 -26.251 27.398 1.00 33.47 N ANISOU 1626 N3 5CM E 28 4973 3387 4358 540 -291 -535 N HETATM 1627 C4 5CM E 28 -16.709 -26.374 26.713 1.00 31.70 C ANISOU 1627 C4 5CM E 28 4712 3126 4206 283 -293 -619 C HETATM 1628 C5 5CM E 28 -16.073 -27.681 26.593 1.00 28.91 C ANISOU 1628 C5 5CM E 28 4124 2899 3962 223 -265 -618 C HETATM 1629 C5A 5CM E 28 -14.761 -27.836 25.852 1.00 27.06 C ANISOU 1629 C5A 5CM E 28 3794 2695 3794 15 -226 -711 C HETATM 1630 C6 5CM E 28 -16.707 -28.841 27.183 1.00 30.39 C ANISOU 1630 C6 5CM E 28 4172 3173 4202 378 -245 -509 C HETATM 1631 O2 5CM E 28 -19.653 -27.379 28.576 1.00 38.18 O ANISOU 1631 O2 5CM E 28 5325 4247 4933 869 -204 -315 O HETATM 1632 N4 5CM E 28 -16.064 -25.251 26.146 1.00 29.51 N ANISOU 1632 N4 5CM E 28 4626 2681 3906 91 -297 -690 N HETATM 1633 C1' 5CM E 28 -18.525 -29.883 28.433 1.00 39.41 C ANISOU 1633 C1' 5CM E 28 5188 4437 5350 642 -173 -241 C HETATM 1634 C2' 5CM E 28 -18.835 -30.926 27.311 1.00 31.02 C ANISOU 1634 C2' 5CM E 28 4027 3295 4464 482 -150 -219 C HETATM 1635 C3' 5CM E 28 -18.423 -32.252 27.908 1.00 31.64 C ANISOU 1635 C3' 5CM E 28 4026 3328 4667 508 -102 -129 C HETATM 1636 C4' 5CM E 28 -17.999 -31.983 29.156 1.00 35.36 C ANISOU 1636 C4' 5CM E 28 4516 3907 5013 676 -108 -69 C HETATM 1637 O4' 5CM E 28 -17.594 -30.439 29.135 1.00 33.68 O ANISOU 1637 O4' 5CM E 28 4420 3747 4628 679 -188 -243 O HETATM 1638 O3' 5CM E 28 -19.663 -33.049 28.000 1.00 29.26 O ANISOU 1638 O3' 5CM E 28 3628 3010 4479 457 -41 40 O HETATM 1639 C5' 5CM E 28 -16.820 -32.763 29.632 1.00 28.20 C ANISOU 1639 C5' 5CM E 28 3572 2992 4149 756 -129 -56 C HETATM 1640 O5' 5CM E 28 -15.803 -32.754 28.649 1.00 32.96 O ANISOU 1640 O5' 5CM E 28 4147 3540 4835 651 -159 -241 O HETATM 1641 P 5CM E 28 -14.365 -33.340 28.969 1.00 33.72 P ANISOU 1641 P 5CM E 28 4134 3704 4975 775 -196 -276 P HETATM 1642 OP1 5CM E 28 -14.431 -34.592 29.820 1.00 34.03 O ANISOU 1642 OP1 5CM E 28 4171 3677 5081 987 -164 -50 O HETATM 1643 OP2 5CM E 28 -13.600 -33.497 27.677 1.00 32.40 O ANISOU 1643 OP2 5CM E 28 3906 3485 4917 665 -146 -456 O ATOM 1644 P DG E 29 -20.445 -33.535 26.684 1.00 33.24 P ANISOU 1644 P DG E 29 4075 3434 5120 230 -80 -32 P ATOM 1645 OP1 DG E 29 -21.074 -34.831 27.052 1.00 29.24 O ANISOU 1645 OP1 DG E 29 3482 2813 4816 115 -11 127 O ATOM 1646 OP2 DG E 29 -19.588 -33.463 25.487 1.00 35.83 O ANISOU 1646 OP2 DG E 29 4508 3671 5434 142 -135 -259 O ATOM 1647 O5' DG E 29 -21.575 -32.428 26.496 1.00 33.28 O ANISOU 1647 O5' DG E 29 4004 3645 4996 280 -124 7 O ATOM 1648 C5' DG E 29 -22.347 -32.020 27.598 1.00 34.91 C ANISOU 1648 C5' DG E 29 4113 4026 5123 455 -44 184 C ATOM 1649 C4' DG E 29 -23.392 -30.999 27.175 1.00 27.28 C ANISOU 1649 C4' DG E 29 3065 3244 4055 562 -93 195 C ATOM 1650 O4' DG E 29 -22.744 -29.745 26.827 1.00 31.62 O ANISOU 1650 O4' DG E 29 3854 3718 4443 688 -159 55 O ATOM 1651 C3' DG E 29 -24.220 -31.388 25.966 1.00 29.81 C ANISOU 1651 C3' DG E 29 3219 3632 4476 363 -208 168 C ATOM 1652 O3' DG E 29 -25.511 -30.861 26.116 1.00 30.76 O ANISOU 1652 O3' DG E 29 3104 4031 4551 509 -208 299 O ATOM 1653 C2' DG E 29 -23.470 -30.729 24.807 1.00 33.09 C ANISOU 1653 C2' DG E 29 3863 3935 4775 340 -328 -16 C ATOM 1654 C1' DG E 29 -22.933 -29.447 25.454 1.00 26.95 C ANISOU 1654 C1' DG E 29 3294 3111 3835 589 -277 -19 C ATOM 1655 N9 DG E 29 -21.636 -29.016 24.942 1.00 30.75 N ANISOU 1655 N9 DG E 29 4020 3409 4256 507 -297 -164 N ATOM 1656 C8 DG E 29 -20.582 -29.832 24.551 1.00 26.40 C ANISOU 1656 C8 DG E 29 3495 2749 3785 320 -279 -276 C ATOM 1657 N7 DG E 29 -19.524 -29.165 24.171 1.00 29.79 N ANISOU 1657 N7 DG E 29 4091 3092 4137 273 -268 -372 N ATOM 1658 C5 DG E 29 -19.891 -27.822 24.330 1.00 36.13 C ANISOU 1658 C5 DG E 29 5044 3870 4816 407 -292 -322 C ATOM 1659 C6 DG E 29 -19.152 -26.636 24.081 1.00 36.10 C ANISOU 1659 C6 DG E 29 5277 3720 4719 368 -285 -367 C ATOM 1660 O6 DG E 29 -17.988 -26.523 23.658 1.00 34.22 O ANISOU 1660 O6 DG E 29 5100 3415 4486 177 -243 -448 O ATOM 1661 N1 DG E 29 -19.897 -25.492 24.376 1.00 31.80 N ANISOU 1661 N1 DG E 29 4900 3099 4083 576 -312 -298 N ATOM 1662 C2 DG E 29 -21.186 -25.493 24.858 1.00 32.04 C ANISOU 1662 C2 DG E 29 4819 3260 4095 836 -327 -201 C ATOM 1663 N2 DG E 29 -21.743 -24.286 25.078 1.00 36.17 N ANISOU 1663 N2 DG E 29 5546 3676 4521 1096 -334 -159 N ATOM 1664 N3 DG E 29 -21.886 -26.592 25.096 1.00 30.77 N ANISOU 1664 N3 DG E 29 4364 3309 4017 841 -320 -141 N ATOM 1665 C4 DG E 29 -21.181 -27.717 24.812 1.00 29.53 C ANISOU 1665 C4 DG E 29 4102 3151 3967 598 -310 -205 C ATOM 1666 P DG E 30 -26.754 -31.484 25.322 1.00 33.91 P ANISOU 1666 P DG E 30 3149 4651 5084 289 -326 345 P ATOM 1667 OP1 DG E 30 -27.945 -31.186 26.144 1.00 37.84 O ANISOU 1667 OP1 DG E 30 3310 5487 5580 478 -210 558 O ATOM 1668 OP2 DG E 30 -26.452 -32.871 24.909 1.00 43.02 O ANISOU 1668 OP2 DG E 30 4301 5599 6445 -102 -363 259 O ATOM 1669 O5' DG E 30 -26.810 -30.649 23.970 1.00 31.58 O ANISOU 1669 O5' DG E 30 2959 4415 4626 359 -543 215 O ATOM 1670 C5' DG E 30 -27.083 -29.270 24.028 1.00 39.03 C ANISOU 1670 C5' DG E 30 3987 5463 5379 738 -552 281 C ATOM 1671 C4' DG E 30 -26.568 -28.578 22.794 1.00 34.53 C ANISOU 1671 C4' DG E 30 3700 4782 4637 763 -707 178 C ATOM 1672 O4' DG E 30 -25.112 -28.491 22.846 1.00 35.93 O ANISOU 1672 O4' DG E 30 4238 4628 4786 667 -619 54 O ATOM 1673 C3' DG E 30 -26.896 -29.285 21.453 1.00 40.10 C ANISOU 1673 C3' DG E 30 4287 5622 5326 490 -926 77 C ATOM 1674 O3' DG E 30 -27.316 -28.307 20.547 1.00 39.85 O ANISOU 1674 O3' DG E 30 4328 5744 5069 714 -1088 139 O ATOM 1675 C2' DG E 30 -25.530 -29.829 21.029 1.00 33.16 C ANISOU 1675 C2' DG E 30 3717 4437 4447 251 -872 -112 C ATOM 1676 C1' DG E 30 -24.680 -28.685 21.537 1.00 28.78 C ANISOU 1676 C1' DG E 30 3462 3683 3789 484 -737 -60 C ATOM 1677 N9 DG E 30 -23.250 -28.880 21.468 1.00 38.39 N ANISOU 1677 N9 DG E 30 4926 4649 5012 337 -632 -191 N ATOM 1678 C8 DG E 30 -22.555 -30.070 21.417 1.00 40.79 C ANISOU 1678 C8 DG E 30 5207 4845 5445 110 -581 -333 C ATOM 1679 N7 DG E 30 -21.264 -29.902 21.296 1.00 31.92 N ANISOU 1679 N7 DG E 30 4277 3567 4283 70 -483 -422 N ATOM 1680 C5 DG E 30 -21.106 -28.518 21.236 1.00 32.23 C ANISOU 1680 C5 DG E 30 4495 3578 4171 206 -473 -334 C ATOM 1681 C6 DG E 30 -19.943 -27.738 21.087 1.00 33.00 C ANISOU 1681 C6 DG E 30 4809 3536 4193 161 -381 -361 C ATOM 1682 O6 DG E 30 -18.769 -28.126 20.991 1.00 38.28 O ANISOU 1682 O6 DG E 30 5490 4150 4903 18 -283 -470 O ATOM 1683 N1 DG E 30 -20.238 -26.368 21.073 1.00 35.33 N ANISOU 1683 N1 DG E 30 5304 3748 4371 304 -401 -236 N ATOM 1684 C2 DG E 30 -21.510 -25.843 21.178 1.00 40.19 C ANISOU 1684 C2 DG E 30 5896 4443 4932 550 -497 -105 C ATOM 1685 N2 DG E 30 -21.621 -24.508 21.142 1.00 33.78 N ANISOU 1685 N2 DG E 30 5350 3466 4017 725 -495 6 N ATOM 1686 N3 DG E 30 -22.599 -26.572 21.303 1.00 33.93 N ANISOU 1686 N3 DG E 30 4825 3870 4198 618 -582 -78 N ATOM 1687 C4 DG E 30 -22.325 -27.887 21.323 1.00 31.80 C ANISOU 1687 C4 DG E 30 4378 3649 4057 399 -566 -196 C ATOM 1688 P DG E 31 -28.592 -28.507 19.610 1.00 45.73 P ANISOU 1688 P DG E 31 4718 6920 5738 695 -1373 172 P ATOM 1689 OP1 DG E 31 -29.748 -28.686 20.514 1.00 42.27 O ANISOU 1689 OP1 DG E 31 3801 6777 5481 790 -1329 315 O ATOM 1690 OP2 DG E 31 -28.277 -29.514 18.575 1.00 60.26 O ANISOU 1690 OP2 DG E 31 6602 8753 7543 300 -1532 -54 O ATOM 1691 O5' DG E 31 -28.688 -27.089 18.867 1.00 52.38 O ANISOU 1691 O5' DG E 31 5813 7809 6279 1100 -1482 317 O ATOM 1692 C5' DG E 31 -28.614 -25.899 19.634 1.00 42.98 C ANISOU 1692 C5' DG E 31 4823 6442 5067 1511 -1318 473 C ATOM 1693 C4' DG E 31 -27.784 -24.847 18.927 1.00 45.13 C ANISOU 1693 C4' DG E 31 5621 6412 5112 1649 -1309 530 C ATOM 1694 O4' DG E 31 -26.374 -25.139 19.103 1.00 41.98 O ANISOU 1694 O4' DG E 31 5527 5651 4773 1335 -1131 376 O ATOM 1695 C3' DG E 31 -28.018 -24.741 17.418 1.00 47.56 C ANISOU 1695 C3' DG E 31 6001 6934 5138 1644 -1558 586 C ATOM 1696 O3' DG E 31 -28.086 -23.392 17.058 1.00 48.66 O ANISOU 1696 O3' DG E 31 6477 6935 5078 2045 -1572 819 O ATOM 1697 C2' DG E 31 -26.783 -25.404 16.827 1.00 47.15 C ANISOU 1697 C2' DG E 31 6202 6684 5031 1224 -1481 391 C ATOM 1698 C1' DG E 31 -25.729 -25.061 17.862 1.00 39.98 C ANISOU 1698 C1' DG E 31 5539 5350 4302 1181 -1195 355 C ATOM 1699 N9 DG E 31 -24.628 -26.001 17.861 1.00 47.72 N ANISOU 1699 N9 DG E 31 6567 6188 5377 801 -1071 139 N ATOM 1700 C8 DG E 31 -24.712 -27.365 17.962 1.00 43.05 C ANISOU 1700 C8 DG E 31 5710 5708 4938 534 -1104 -51 C ATOM 1701 N7 DG E 31 -23.554 -27.955 17.931 1.00 43.37 N ANISOU 1701 N7 DG E 31 5886 5557 5035 304 -961 -215 N ATOM 1702 C5 DG E 31 -22.647 -26.914 17.800 1.00 38.98 C ANISOU 1702 C5 DG E 31 5648 4803 4359 373 -826 -126 C ATOM 1703 C6 DG E 31 -21.241 -26.950 17.702 1.00 36.77 C ANISOU 1703 C6 DG E 31 5549 4340 4083 197 -638 -218 C ATOM 1704 O6 DG E 31 -20.498 -27.955 17.715 1.00 31.73 O ANISOU 1704 O6 DG E 31 4833 3680 3544 14 -551 -407 O ATOM 1705 N1 DG E 31 -20.701 -25.663 17.575 1.00 30.85 N ANISOU 1705 N1 DG E 31 5086 3413 3222 256 -542 -61 N ATOM 1706 C2 DG E 31 -21.444 -24.498 17.552 1.00 42.23 C ANISOU 1706 C2 DG E 31 6694 4790 4563 508 -619 157 C ATOM 1707 N2 DG E 31 -20.761 -23.337 17.426 1.00 31.19 N ANISOU 1707 N2 DG E 31 5635 3118 3099 495 -498 295 N ATOM 1708 N3 DG E 31 -22.768 -24.469 17.641 1.00 39.78 N ANISOU 1708 N3 DG E 31 6217 4665 4234 761 -797 242 N ATOM 1709 C4 DG E 31 -23.294 -25.706 17.753 1.00 41.90 C ANISOU 1709 C4 DG E 31 6139 5174 4608 653 -892 92 C ATOM 1710 P DA E 32 -28.310 -22.945 15.532 1.00 62.62 P ANISOU 1710 P DA E 32 8432 8900 6462 2177 -1811 987 P ATOM 1711 OP1 DA E 32 -29.255 -21.805 15.564 1.00 65.12 O ANISOU 1711 OP1 DA E 32 8745 9255 6743 2668 -1855 1245 O ATOM 1712 OP2 DA E 32 -28.559 -24.134 14.689 1.00 65.95 O ANISOU 1712 OP2 DA E 32 8562 9724 6772 1836 -2037 793 O ATOM 1713 O5' DA E 32 -26.886 -22.387 15.108 1.00 54.76 O ANISOU 1713 O5' DA E 32 8028 7439 5338 1997 -1596 1021 O ATOM 1714 C5' DA E 32 -26.183 -21.544 15.990 1.00 51.12 C ANISOU 1714 C5' DA E 32 7897 6475 5050 2063 -1340 1068 C ATOM 1715 C4' DA E 32 -24.923 -21.033 15.334 1.00 56.22 C ANISOU 1715 C4' DA E 32 9030 6779 5550 1826 -1170 1140 C ATOM 1716 O4' DA E 32 -23.876 -22.028 15.459 1.00 55.84 O ANISOU 1716 O4' DA E 32 8879 6720 5618 1354 -1026 867 O ATOM 1717 C3' DA E 32 -25.041 -20.740 13.845 1.00 58.22 C ANISOU 1717 C3' DA E 32 9503 7225 5395 1901 -1301 1364 C ATOM 1718 O3' DA E 32 -24.189 -19.654 13.528 1.00 69.64 O ANISOU 1718 O3' DA E 32 11487 8229 6744 1875 -1099 1600 O ATOM 1719 C2' DA E 32 -24.560 -22.044 13.205 1.00 55.34 C ANISOU 1719 C2' DA E 32 8930 7173 4926 1490 -1325 1093 C ATOM 1720 C1' DA E 32 -23.475 -22.476 14.179 1.00 55.00 C ANISOU 1720 C1' DA E 32 8852 6827 5219 1154 -1058 855 C ATOM 1721 N9 DA E 32 -23.257 -23.926 14.254 1.00 59.64 N ANISOU 1721 N9 DA E 32 9112 7631 5918 853 -1074 524 N ATOM 1722 C8 DA E 32 -24.193 -24.914 14.385 1.00 57.13 C ANISOU 1722 C8 DA E 32 8401 7621 5685 844 -1284 358 C ATOM 1723 N7 DA E 32 -23.679 -26.129 14.453 1.00 46.74 N ANISOU 1723 N7 DA E 32 6935 6328 4494 535 -1225 69 N ATOM 1724 C5 DA E 32 -22.319 -25.915 14.369 1.00 50.54 C ANISOU 1724 C5 DA E 32 7679 6566 4957 379 -962 44 C ATOM 1725 C6 DA E 32 -21.205 -26.787 14.384 1.00 48.53 C ANISOU 1725 C6 DA E 32 7411 6232 4797 119 -775 -195 C ATOM 1726 N6 DA E 32 -21.288 -28.128 14.490 1.00 33.39 N ANISOU 1726 N6 DA E 32 5280 4386 3019 -29 -827 -472 N ATOM 1727 N1 DA E 32 -19.991 -26.226 14.283 1.00 45.86 N ANISOU 1727 N1 DA E 32 7284 5723 4419 21 -524 -130 N ATOM 1728 C2 DA E 32 -19.885 -24.901 14.178 1.00 47.74 C ANISOU 1728 C2 DA E 32 7782 5806 4551 113 -461 151 C ATOM 1729 N3 DA E 32 -20.842 -23.989 14.156 1.00 54.50 N ANISOU 1729 N3 DA E 32 8758 6631 5319 373 -614 392 N ATOM 1730 C4 DA E 32 -22.045 -24.563 14.254 1.00 52.53 C ANISOU 1730 C4 DA E 32 8245 6625 5091 527 -865 323 C ATOM 1731 P DA E 33 -24.202 -18.981 12.072 1.00 68.22 P ANISOU 1731 P DA E 33 11600 8141 6180 1950 -1123 1914 P ATOM 1732 OP1 DA E 33 -24.309 -17.530 12.306 1.00 78.71 O ANISOU 1732 OP1 DA E 33 13205 9025 7675 2150 -995 2144 O ATOM 1733 OP2 DA E 33 -25.154 -19.705 11.189 1.00 70.83 O ANISOU 1733 OP2 DA E 33 11602 9082 6229 2075 -1432 1879 O ATOM 1734 O5' DA E 33 -22.738 -19.268 11.512 1.00 61.13 O ANISOU 1734 O5' DA E 33 11000 7123 5101 1498 -870 1899 O ATOM 1735 C5' DA E 33 -21.625 -19.133 12.368 1.00 52.94 C ANISOU 1735 C5' DA E 33 10031 5679 4403 1151 -586 1754 C ATOM 1736 C4' DA E 33 -20.412 -19.766 11.734 1.00 54.23 C ANISOU 1736 C4' DA E 33 10173 5987 4443 705 -359 1630 C ATOM 1737 O4' DA E 33 -20.443 -21.207 11.929 1.00 53.43 O ANISOU 1737 O4' DA E 33 9620 6251 4429 570 -443 1229 O ATOM 1738 C3' DA E 33 -20.304 -19.540 10.232 1.00 59.56 C ANISOU 1738 C3' DA E 33 11129 6896 4603 725 -322 1910 C ATOM 1739 O3' DA E 33 -18.983 -19.156 9.929 1.00 58.95 O ANISOU 1739 O3' DA E 33 11277 6618 4504 349 44 2026 O ATOM 1740 C2' DA E 33 -20.676 -20.904 9.624 1.00 56.73 C ANISOU 1740 C2' DA E 33 10427 7112 4014 711 -507 1595 C ATOM 1741 C1' DA E 33 -20.208 -21.861 10.701 1.00 50.17 C ANISOU 1741 C1' DA E 33 9215 6219 3628 466 -433 1176 C ATOM 1742 N9 DA E 33 -20.912 -23.150 10.729 1.00 58.52 N ANISOU 1742 N9 DA E 33 9894 7634 4707 495 -678 832 N ATOM 1743 C8 DA E 33 -22.266 -23.371 10.695 1.00 61.97 C ANISOU 1743 C8 DA E 33 10134 8323 5089 749 -1031 821 C ATOM 1744 N7 DA E 33 -22.598 -24.646 10.764 1.00 58.55 N ANISOU 1744 N7 DA E 33 9367 8135 4743 615 -1179 466 N ATOM 1745 C5 DA E 33 -21.381 -25.300 10.862 1.00 54.09 C ANISOU 1745 C5 DA E 33 8816 7447 4290 323 -902 232 C ATOM 1746 C6 DA E 33 -21.025 -26.664 10.973 1.00 52.85 C ANISOU 1746 C6 DA E 33 8449 7357 4274 109 -873 -165 C ATOM 1747 N6 DA E 33 -21.901 -27.678 11.003 1.00 49.72 N ANISOU 1747 N6 DA E 33 7799 7139 3953 70 -1137 -419 N ATOM 1748 N1 DA E 33 -19.719 -26.950 11.050 1.00 55.19 N ANISOU 1748 N1 DA E 33 8802 7516 4651 -69 -557 -285 N ATOM 1749 C2 DA E 33 -18.824 -25.964 11.022 1.00 56.23 C ANISOU 1749 C2 DA E 33 9137 7488 4740 -112 -291 -38 C ATOM 1750 N3 DA E 33 -19.027 -24.662 10.927 1.00 54.74 N ANISOU 1750 N3 DA E 33 9188 7167 4444 -2 -282 333 N ATOM 1751 C4 DA E 33 -20.336 -24.389 10.847 1.00 55.39 C ANISOU 1751 C4 DA E 33 9259 7355 4433 250 -596 454 C ATOM 1752 P DG E 34 -18.547 -18.850 8.421 1.00 73.60 P ANISOU 1752 P DG E 34 13391 8710 5866 276 219 2327 P ATOM 1753 OP1 DG E 34 -17.623 -17.698 8.493 1.00 84.63 O ANISOU 1753 OP1 DG E 34 15011 9662 7481 5 532 2598 O ATOM 1754 OP2 DG E 34 -19.745 -18.788 7.556 1.00 76.98 O ANISOU 1754 OP2 DG E 34 13792 9490 5968 674 -101 2459 O ATOM 1755 O5' DG E 34 -17.708 -20.144 8.043 1.00 71.10 O ANISOU 1755 O5' DG E 34 12819 8807 5388 -10 390 1973 O ATOM 1756 C5' DG E 34 -16.877 -20.718 9.029 1.00 63.18 C ANISOU 1756 C5' DG E 34 11480 7682 4844 -297 543 1629 C ATOM 1757 C4' DG E 34 -16.063 -21.859 8.463 1.00 63.11 C ANISOU 1757 C4' DG E 34 11231 8080 4668 -479 735 1323 C ATOM 1758 O4' DG E 34 -16.766 -23.111 8.662 1.00 66.31 O ANISOU 1758 O4' DG E 34 11340 8733 5121 -319 452 909 O ATOM 1759 C3' DG E 34 -15.763 -21.773 6.974 1.00 65.68 C ANISOU 1759 C3' DG E 34 11816 8757 4382 -480 924 1529 C ATOM 1760 O3' DG E 34 -14.459 -22.280 6.753 1.00 73.09 O ANISOU 1760 O3' DG E 34 12573 9879 5319 -756 1317 1367 O ATOM 1761 C2' DG E 34 -16.843 -22.667 6.357 1.00 64.42 C ANISOU 1761 C2' DG E 34 11603 8998 3875 -187 559 1284 C ATOM 1762 C1' DG E 34 -16.974 -23.747 7.420 1.00 66.88 C ANISOU 1762 C1' DG E 34 11494 9243 4673 -226 405 805 C ATOM 1763 N9 DG E 34 -18.279 -24.403 7.462 1.00 73.14 N ANISOU 1763 N9 DG E 34 12149 10205 5434 -7 -35 591 N ATOM 1764 C8 DG E 34 -19.522 -23.812 7.442 1.00 76.48 C ANISOU 1764 C8 DG E 34 12648 10644 5769 256 -378 818 C ATOM 1765 N7 DG E 34 -20.508 -24.672 7.510 1.00 71.11 N ANISOU 1765 N7 DG E 34 11714 10192 5114 350 -732 533 N ATOM 1766 C5 DG E 34 -19.871 -25.904 7.594 1.00 66.48 C ANISOU 1766 C5 DG E 34 10943 9662 4653 132 -611 90 C ATOM 1767 C6 DG E 34 -20.410 -27.207 7.688 1.00 63.63 C ANISOU 1767 C6 DG E 34 10329 9446 4402 67 -848 -352 C ATOM 1768 O6 DG E 34 -21.602 -27.545 7.726 1.00 66.00 O ANISOU 1768 O6 DG E 34 10451 9910 4718 138 -1230 -445 O ATOM 1769 N1 DG E 34 -19.407 -28.177 7.747 1.00 57.82 N ANISOU 1769 N1 DG E 34 9542 8641 3788 -107 -593 -700 N ATOM 1770 C2 DG E 34 -18.057 -27.912 7.715 1.00 65.67 C ANISOU 1770 C2 DG E 34 10628 9537 4787 -193 -166 -627 C ATOM 1771 N2 DG E 34 -17.237 -28.965 7.776 1.00 57.85 N ANISOU 1771 N2 DG E 34 9532 8529 3919 -278 32 -992 N ATOM 1772 N3 DG E 34 -17.543 -26.697 7.626 1.00 75.01 N ANISOU 1772 N3 DG E 34 11986 10635 5877 -200 57 -216 N ATOM 1773 C4 DG E 34 -18.502 -25.748 7.571 1.00 71.34 C ANISOU 1773 C4 DG E 34 11657 10146 5301 -42 -183 123 C ATOM 1774 P DC E 35 -13.812 -22.324 5.285 1.00 95.52 P ANISOU 1774 P DC E 35 15592 13155 7548 -800 1651 1520 P ATOM 1775 OP1 DC E 35 -12.366 -22.074 5.481 1.00 89.86 O ANISOU 1775 OP1 DC E 35 14676 12398 7070 -1160 2121 1593 O ATOM 1776 OP2 DC E 35 -14.614 -21.494 4.351 1.00 95.37 O ANISOU 1776 OP2 DC E 35 15846 13208 7181 -565 1462 1912 O ATOM 1777 O5' DC E 35 -13.985 -23.850 4.858 1.00 97.08 O ANISOU 1777 O5' DC E 35 15598 13786 7502 -631 1537 972 O ATOM 1778 C5' DC E 35 -13.543 -24.879 5.738 1.00 87.70 C ANISOU 1778 C5' DC E 35 14005 12536 6782 -691 1545 509 C ATOM 1779 C4' DC E 35 -13.581 -26.221 5.042 1.00 83.34 C ANISOU 1779 C4' DC E 35 13394 12354 5917 -530 1512 32 C ATOM 1780 O4' DC E 35 -14.883 -26.833 5.240 1.00 79.06 O ANISOU 1780 O4' DC E 35 12850 11770 5418 -358 1010 -223 O ATOM 1781 C3' DC E 35 -13.372 -26.153 3.533 1.00 88.16 C ANISOU 1781 C3' DC E 35 14210 13410 5875 -415 1683 130 C ATOM 1782 O3' DC E 35 -12.616 -27.259 3.106 1.00 90.37 O ANISOU 1782 O3' DC E 35 14309 13958 6069 -324 1901 -293 O ATOM 1783 C2' DC E 35 -14.796 -26.207 2.987 1.00 89.77 C ANISOU 1783 C2' DC E 35 14591 13750 5769 -196 1179 106 C ATOM 1784 C1' DC E 35 -15.458 -27.134 3.988 1.00 82.38 C ANISOU 1784 C1' DC E 35 13505 12579 5216 -196 850 -321 C ATOM 1785 N1 DC E 35 -16.925 -26.950 4.093 1.00 80.17 N ANISOU 1785 N1 DC E 35 13277 12276 4908 -65 325 -258 N ATOM 1786 C2 DC E 35 -17.742 -28.074 4.132 1.00 79.59 C ANISOU 1786 C2 DC E 35 13048 12291 4902 -24 -46 -724 C ATOM 1787 O2 DC E 35 -17.214 -29.186 4.069 1.00 81.36 O ANISOU 1787 O2 DC E 35 13162 12536 5214 -69 75 -1175 O ATOM 1788 N3 DC E 35 -19.087 -27.914 4.234 1.00 72.57 N ANISOU 1788 N3 DC E 35 12092 11454 4027 66 -519 -658 N ATOM 1789 C4 DC E 35 -19.605 -26.686 4.293 1.00 70.70 C ANISOU 1789 C4 DC E 35 11959 11172 3731 199 -621 -153 C ATOM 1790 N4 DC E 35 -20.933 -26.571 4.388 1.00 67.81 N ANISOU 1790 N4 DC E 35 11443 10912 3409 327 -1073 -97 N ATOM 1791 C5 DC E 35 -18.780 -25.519 4.254 1.00 73.97 C ANISOU 1791 C5 DC E 35 12602 11411 4093 190 -247 322 C ATOM 1792 C6 DC E 35 -17.458 -25.697 4.156 1.00 76.14 C ANISOU 1792 C6 DC E 35 12919 11649 4361 15 215 254 C ATOM 1793 P DA E 36 -11.624 -27.125 1.849 1.00117.19 P ANISOU 1793 P DA E 36 17708 17799 9018 -236 2327 -153 P ATOM 1794 OP1 DA E 36 -10.365 -26.528 2.348 1.00114.51 O ANISOU 1794 OP1 DA E 36 17140 17366 9004 -491 2791 122 O ATOM 1795 OP2 DA E 36 -12.342 -26.474 0.726 1.00111.65 O ANISOU 1795 OP2 DA E 36 17270 17391 7759 -132 2155 148 O ATOM 1796 O5' DA E 36 -11.349 -28.647 1.452 1.00112.17 O ANISOU 1796 O5' DA E 36 16983 17354 8283 41 2343 -773 O ATOM 1797 C5' DA E 36 -12.201 -29.674 1.957 1.00104.73 C ANISOU 1797 C5' DA E 36 16046 16182 7564 129 1925 -1248 C ATOM 1798 C4' DA E 36 -12.944 -30.359 0.825 1.00107.00 C ANISOU 1798 C4' DA E 36 16588 16654 7412 381 1627 -1542 C ATOM 1799 O4' DA E 36 -14.360 -30.054 0.921 1.00105.93 O ANISOU 1799 O4' DA E 36 16459 16544 7245 283 1103 -1491 O ATOM 1800 C3' DA E 36 -12.516 -29.929 -0.580 1.00110.53 C ANISOU 1800 C3' DA E 36 17301 17416 7278 539 1883 -1310 C ATOM 1801 O3' DA E 36 -12.542 -31.047 -1.456 1.00115.09 O ANISOU 1801 O3' DA E 36 18313 17818 7599 184 1960 -1836 O ATOM 1802 C2' DA E 36 -13.580 -28.903 -0.957 1.00110.22 C ANISOU 1802 C2' DA E 36 17185 17742 6951 -8 1572 -1014 C ATOM 1803 C1' DA E 36 -14.806 -29.518 -0.306 1.00109.71 C ANISOU 1803 C1' DA E 36 17163 17352 7170 -50 1057 -1315 C ATOM 1804 N9 DA E 36 -15.883 -28.569 -0.038 1.00109.81 N ANISOU 1804 N9 DA E 36 17228 17344 7150 -15 690 -915 N ATOM 1805 C8 DA E 36 -15.858 -27.208 -0.190 1.00110.76 C ANISOU 1805 C8 DA E 36 17464 17535 7084 16 789 -295 C ATOM 1806 N7 DA E 36 -16.992 -26.618 0.130 1.00104.85 N ANISOU 1806 N7 DA E 36 16779 16637 6421 70 386 -46 N ATOM 1807 C5 DA E 36 -17.811 -27.666 0.515 1.00 98.88 C ANISOU 1807 C5 DA E 36 15897 15805 5867 44 1 -532 C ATOM 1808 C6 DA E 36 -19.146 -27.721 0.966 1.00 89.15 C ANISOU 1808 C6 DA E 36 14577 14469 4828 85 -511 -558 C ATOM 1809 N6 DA E 36 -19.938 -26.645 1.116 1.00 83.35 N ANISOU 1809 N6 DA E 36 13869 13698 4102 231 -738 -85 N ATOM 1810 N1 DA E 36 -19.642 -28.935 1.262 1.00 82.86 N ANISOU 1810 N1 DA E 36 13651 13575 4258 -25 -768 -1076 N ATOM 1811 C2 DA E 36 -18.876 -30.013 1.116 1.00 84.96 C ANISOU 1811 C2 DA E 36 13960 13738 4582 -125 -538 -1527 C ATOM 1812 N3 DA E 36 -17.620 -30.092 0.702 1.00 91.97 N ANISOU 1812 N3 DA E 36 14936 14681 5326 -115 -62 -1567 N ATOM 1813 C4 DA E 36 -17.140 -28.874 0.415 1.00101.61 C ANISOU 1813 C4 DA E 36 16180 16134 6293 -40 188 -1061 C TER 1814 DA E 36 HETATM 1815 ZN ZN A 701 -12.395 -10.339 18.979 1.00 49.50 ZN HETATM 1816 ZN ZN A 702 -0.862 -32.319 16.579 1.00 46.02 ZN HETATM 1817 ZN ZN A 703 -25.970 -46.713 18.369 1.00 33.80 ZN HETATM 1818 CL CL A 704 -11.102 -45.872 23.360 0.50 35.01 CL HETATM 1819 O1 TLA A 705 -15.669 -29.704 18.302 1.00 33.54 O HETATM 1820 O11 TLA A 705 -15.237 -28.971 20.352 1.00 33.50 O HETATM 1821 C1 TLA A 705 -15.357 -29.907 19.506 1.00 38.11 C HETATM 1822 C2 TLA A 705 -15.130 -31.328 19.925 1.00 40.96 C HETATM 1823 O2 TLA A 705 -15.404 -32.130 18.797 1.00 36.02 O HETATM 1824 C3 TLA A 705 -16.078 -31.593 21.070 1.00 48.66 C HETATM 1825 O3 TLA A 705 -17.408 -31.284 20.682 1.00 50.03 O HETATM 1826 C4 TLA A 705 -15.968 -33.034 21.547 1.00 49.21 C HETATM 1827 O4 TLA A 705 -17.011 -33.741 21.527 1.00 38.79 O HETATM 1828 O41 TLA A 705 -14.862 -33.510 21.970 1.00 40.04 O HETATM 1829 O HOH A 801 -18.616 -30.247 22.259 1.00 25.08 O HETATM 1830 O HOH A 802 -0.731 -39.144 25.542 1.00 42.36 O HETATM 1831 O HOH A 803 -23.612 -44.628 12.678 1.00 45.71 O HETATM 1832 O HOH A 804 -9.132 -28.524 17.572 1.00 36.17 O HETATM 1833 O HOH A 805 -27.690 -37.938 11.781 1.00 46.94 O HETATM 1834 O HOH A 806 -23.279 -10.106 31.493 1.00 49.43 O HETATM 1835 O HOH A 807 -7.145 -5.142 29.891 1.00 66.45 O HETATM 1836 O HOH A 808 -20.036 -48.603 28.719 1.00 51.11 O HETATM 1837 O HOH A 809 -11.981 -32.234 25.889 1.00 31.55 O HETATM 1838 O HOH A 810 -16.717 -17.814 33.798 1.00 62.84 O HETATM 1839 O HOH A 811 -27.392 -33.746 19.991 1.00 44.65 O HETATM 1840 O HOH A 812 -16.298 -45.549 31.801 1.00 39.87 O HETATM 1841 O HOH A 813 -15.027 -34.171 25.274 1.00 27.44 O HETATM 1842 O HOH A 814 -12.703 -23.592 26.652 1.00 36.73 O HETATM 1843 O HOH A 815 -13.322 -27.098 19.989 1.00 34.05 O HETATM 1844 O HOH A 816 -13.446 -33.538 17.571 1.00 41.57 O HETATM 1845 O HOH A 817 -21.672 -40.681 13.200 1.00 35.15 O HETATM 1846 O HOH A 818 -7.829 -18.713 24.859 1.00 46.27 O HETATM 1847 O HOH A 819 -12.975 -38.101 34.629 1.00 58.73 O HETATM 1848 O HOH A 820 -11.994 -37.361 32.071 1.00 38.07 O HETATM 1849 O HOH A 821 -13.062 -35.548 21.627 1.00 24.88 O HETATM 1850 O HOH A 822 -15.125 -17.622 24.813 1.00 40.22 O HETATM 1851 O HOH A 823 -12.759 -39.331 22.207 1.00 31.54 O HETATM 1852 O HOH A 824 -7.114 -12.769 26.721 1.00 50.43 O HETATM 1853 O HOH A 825 -10.086 -23.307 25.658 1.00 34.24 O HETATM 1854 O HOH A 826 -16.338 -30.890 24.693 1.00 26.64 O HETATM 1855 O HOH A 827 -8.603 -45.432 24.971 1.00 30.89 O HETATM 1856 O HOH A 828 -13.320 -29.430 16.819 1.00 38.48 O HETATM 1857 O HOH A 829 -16.592 -28.887 22.800 1.00 28.23 O HETATM 1858 O HOH A 830 -17.283 -44.025 34.006 1.00 59.38 O HETATM 1859 O HOH A 831 -8.305 -21.174 26.085 1.00 41.15 O HETATM 1860 O HOH A 832 3.912 -35.685 14.204 1.00 65.00 O HETATM 1861 O HOH A 833 -10.316 -47.101 31.440 1.00 35.34 O HETATM 1862 O HOH A 834 -24.015 -33.787 15.137 1.00 43.83 O HETATM 1863 O HOH A 835 -15.712 -41.203 15.653 1.00 38.44 O HETATM 1864 O HOH A 836 -26.656 -33.779 15.534 1.00 61.99 O HETATM 1865 O HOH A 837 2.314 -19.329 25.971 1.00 68.06 O HETATM 1866 O HOH A 838 -7.416 -31.283 14.524 1.00 53.25 O HETATM 1867 O HOH A 839 -37.721 -39.859 18.793 1.00 53.03 O HETATM 1868 O HOH A 840 3.559 -37.902 17.175 1.00 59.45 O HETATM 1869 O HOH A 841 -11.717 -34.569 19.380 1.00 31.36 O HETATM 1870 O HOH A 842 -12.792 -35.438 24.146 1.00 35.82 O HETATM 1871 O HOH A 843 -4.985 -43.204 31.931 1.00 64.93 O HETATM 1872 O HOH A 844 -24.624 -38.400 29.211 1.00 53.85 O HETATM 1873 O HOH A 845 -13.483 -18.921 20.610 1.00 36.28 O HETATM 1874 O HOH A 846 -17.314 -14.233 33.616 1.00 61.65 O HETATM 1875 O HOH A 847 -9.636 -31.147 16.238 1.00 48.81 O HETATM 1876 O HOH A 848 -35.576 -45.459 24.699 1.00 54.96 O HETATM 1877 O HOH A 849 -21.092 -30.914 31.152 1.00 45.46 O HETATM 1878 O HOH A 850 -14.002 -45.572 32.711 1.00 52.52 O HETATM 1879 O HOH A 851 -10.061 -43.275 33.169 1.00 41.63 O HETATM 1880 O HOH D 101 -22.349 -14.411 23.494 1.00 51.70 O HETATM 1881 O HOH D 102 -22.582 -20.605 24.065 1.00 54.94 O HETATM 1882 O HOH D 103 -10.133 -19.845 15.830 1.00 52.91 O HETATM 1883 O HOH D 104 -8.151 -33.582 37.234 1.00 49.80 O HETATM 1884 O HOH D 105 -20.049 -13.391 20.316 1.00 48.86 O HETATM 1885 O HOH D 106 -14.179 -16.394 19.235 1.00 40.07 O HETATM 1886 O HOH D 107 -18.892 -21.611 14.752 1.00 54.17 O HETATM 1887 O HOH D 108 -15.248 -17.924 22.156 1.00 43.86 O HETATM 1888 O HOH D 109 -21.373 -20.744 20.841 1.00 42.03 O HETATM 1889 O HOH D 110 -18.050 -27.204 34.932 1.00 48.05 O HETATM 1890 O HOH D 111 -21.108 -26.681 32.664 1.00 50.67 O HETATM 1891 O HOH D 112 -15.142 -18.268 12.914 1.00 54.35 O HETATM 1892 O HOH D 113 -15.584 -18.513 29.584 1.00 31.77 O HETATM 1893 O HOH D 114 -19.160 -18.374 34.571 1.00 54.09 O HETATM 1894 O HOH D 115 -24.418 -23.288 27.540 1.00 40.31 O HETATM 1895 O HOH D 116 -21.501 -18.261 33.720 1.00 56.94 O HETATM 1896 O HOH D 117 -11.714 -27.615 17.898 1.00 29.71 O HETATM 1897 O HOH D 118 -24.071 -19.081 22.098 1.00 45.67 O HETATM 1898 O HOH E 101 -7.042 -29.963 31.302 1.00 45.00 O HETATM 1899 O HOH E 102 -13.048 -34.774 31.864 1.00 43.58 O HETATM 1900 O HOH E 103 -26.196 -34.377 26.894 1.00 41.34 O HETATM 1901 O HOH E 104 -21.345 -35.490 29.493 1.00 37.94 O HETATM 1902 O HOH E 105 -21.872 -28.227 29.639 1.00 37.82 O HETATM 1903 O HOH E 106 -18.395 -32.221 23.512 1.00 30.97 O HETATM 1904 O HOH E 107 -23.137 -30.576 17.630 1.00 44.90 O HETATM 1905 O HOH E 108 -16.581 -23.675 11.698 1.00 51.79 O HETATM 1906 O HOH E 109 -25.040 -25.266 21.514 1.00 38.12 O HETATM 1907 O HOH E 110 -24.065 -22.277 18.878 1.00 36.82 O HETATM 1908 O HOH E 111 -11.490 -29.555 25.718 1.00 29.46 O HETATM 1909 O HOH E 112 -23.416 -22.116 21.477 1.00 43.68 O HETATM 1910 O HOH E 113 -29.617 -26.731 23.115 1.00 69.28 O HETATM 1911 O HOH E 114 -19.302 -29.535 32.423 1.00 56.22 O HETATM 1912 O HOH E 115 -24.652 -26.732 27.442 1.00 71.26 O CONECT 138 1815 CONECT 159 1815 CONECT 271 1815 CONECT 308 1815 CONECT 380 1816 CONECT 409 1816 CONECT 523 1816 CONECT 560 1816 CONECT 629 1817 CONECT 648 1817 CONECT 756 1817 CONECT 796 1817 CONECT 1202 1230 CONECT 1213 1214 1219 1222 CONECT 1214 1213 1215 1220 CONECT 1215 1214 1216 CONECT 1216 1215 1217 1221 CONECT 1217 1216 1218 1219 CONECT 1218 1217 CONECT 1219 1213 1217 CONECT 1220 1214 CONECT 1221 1216 CONECT 1222 1213 1223 1226 CONECT 1223 1222 1224 CONECT 1224 1223 1225 1227 CONECT 1225 1224 1226 1228 CONECT 1226 1222 1225 CONECT 1227 1224 1233 CONECT 1228 1225 1229 CONECT 1229 1228 1230 CONECT 1230 1202 1229 1231 1232 CONECT 1231 1230 CONECT 1232 1230 CONECT 1233 1227 CONECT 1241 1272 CONECT 1255 1256 1261 1264 CONECT 1256 1255 1257 1262 CONECT 1257 1256 1258 CONECT 1258 1257 1259 1263 CONECT 1259 1258 1260 1261 CONECT 1260 1259 CONECT 1261 1255 1259 CONECT 1262 1256 CONECT 1263 1258 CONECT 1264 1255 1265 1268 CONECT 1265 1264 1266 CONECT 1266 1265 1267 1269 CONECT 1267 1266 1268 1270 CONECT 1268 1264 1267 CONECT 1269 1266 1275 CONECT 1270 1267 1271 CONECT 1271 1270 1272 CONECT 1272 1241 1271 1273 1274 CONECT 1273 1272 CONECT 1274 1272 CONECT 1275 1269 CONECT 1570 1599 CONECT 1582 1583 1588 1591 CONECT 1583 1582 1584 1589 CONECT 1584 1583 1585 CONECT 1585 1584 1586 1590 CONECT 1586 1585 1587 1588 CONECT 1587 1586 CONECT 1588 1582 1586 CONECT 1589 1583 CONECT 1590 1585 CONECT 1591 1582 1592 1595 CONECT 1592 1591 1593 CONECT 1593 1592 1594 1596 CONECT 1594 1593 1595 1597 CONECT 1595 1591 1594 CONECT 1596 1593 1602 CONECT 1597 1594 1598 CONECT 1598 1597 1599 CONECT 1599 1570 1598 1600 1601 CONECT 1600 1599 CONECT 1601 1599 CONECT 1602 1596 CONECT 1610 1641 CONECT 1624 1625 1630 1633 CONECT 1625 1624 1626 1631 CONECT 1626 1625 1627 CONECT 1627 1626 1628 1632 CONECT 1628 1627 1629 1630 CONECT 1629 1628 CONECT 1630 1624 1628 CONECT 1631 1625 CONECT 1632 1627 CONECT 1633 1624 1634 1637 CONECT 1634 1633 1635 CONECT 1635 1634 1636 1638 CONECT 1636 1635 1637 1639 CONECT 1637 1633 1636 CONECT 1638 1635 1644 CONECT 1639 1636 1640 CONECT 1640 1639 1641 CONECT 1641 1610 1640 1642 1643 CONECT 1642 1641 CONECT 1643 1641 CONECT 1644 1638 CONECT 1815 138 159 271 308 CONECT 1816 380 409 523 560 CONECT 1817 629 648 756 796 CONECT 1819 1821 CONECT 1820 1821 CONECT 1821 1819 1820 1822 CONECT 1822 1821 1823 1824 CONECT 1823 1822 CONECT 1824 1822 1825 1826 CONECT 1825 1824 CONECT 1826 1824 1827 1828 CONECT 1827 1826 CONECT 1828 1826 MASTER 483 0 9 4 8 0 8 6 1868 3 113 15 END
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Related entries of code: 5vmz
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5vmu
RCSB PDB
PDBbind
18aa, >5VMU_3|Chain... *
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
5vmu
RCSB PDB
PDBbind
double CpG-methylated DNA resembling the specific Kaiso binding sequence, MeKBS(1)
Entry Information
PDB ID
5vmz
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Transcriptional regulator Kaiso (ZBTB33) E535Q mutant zinc finger DNA binding domain
Ligand Name
double CpG-methylated DNA resembling the specific Kaiso binding sequence, MeKBS(1)
EC.Number
E.C.-.-.-.-
Resolution
2.32(Å)
Affinity (Kd/Ki/IC50)
Kd=7.2nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Biochemistry Vol. 57: pp. 2109-2120
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q86T24
Entrez Gene ID
NCBI Entrez Gene ID:
10009
ASD
Information of known allosteric effects of PDB entries
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times since Nov 2007.
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