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Related entries of code: 5x02
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
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Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5x02
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameReceptor-type tyrosine-protein kinase FLT3
Ligand NameF6M
EC.Number E.C.2.7.10.1
Resolution 2.4(Å)
Affinity (Kd/Ki/IC50)IC50=0.14nM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Blood Vol. 131: pp. 426-438
Ligand Properties
Formula C29H41N8O2
Molecular Weight 533.688
Exact Mass 533.335
No. of atoms 80
No. of bonds 81
Polar Surface Area 127.48
LOGP Value 3.59      (Computed with XLOGP3)
2.47      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 5
No. of Rotatable Bonds: 17
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 2
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P36888  
Entrez Gene IDNCBI Entrez Gene ID: 2322  
ASDInformation of known allosteric effects of PDB entries
 
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