Browse entries in the PDBbind-CN Database

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Related entries of code: 5yjp
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1t31RCSB PDB    PDBbind226aa, >1T31_1|Chain... *
2hvxRCSB PDB    PDBbind226aa, >2HVX_1|Chain... at 100%
3n7oRCSB PDB    PDBbind226aa, >3N7O_1|Chain... at 99%
3s0nRCSB PDB    PDBbind226aa, >3S0N_1|Chain... at 100%
4k2yRCSB PDB    PDBbind226aa, >4K2Y_1|Chain... at 100%
4k5zRCSB PDB    PDBbind226aa, >4K5Z_1|Chain... at 100%
4k60RCSB PDB    PDBbind226aa, >4K60_1|Chain... at 100%
4k69RCSB PDB    PDBbind226aa, >4K69_1|Chain... at 100%
4kp0RCSB PDB    PDBbind226aa, >4KP0_1|Chain... at 98%
5yjmRCSB PDB    PDBbind226aa, >5YJM_1|Chain... at 98%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID5yjp
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namehuman chymase
Ligand Name8W6
EC.Number E.C.-.-.-.-
Resolution 1.8(Å)
Affinity (Kd/Ki/IC50)IC50=0.24uM
Release Year2017
Protein/NA SequenceCheck fasta file
Primary Reference (2018) Bioorg. Med. Chem. Lett. Vol. 28: pp. 188-192
Ligand Properties
Formula C26H31ClN4O6
Molecular Weight 531.001
Exact Mass 530.193
No. of atoms 68
No. of bonds 70
Polar Surface Area 129.56
LOGP Value 5.51      (Computed with XLOGP3)
4.51      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 10
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P23946  
Entrez Gene IDNCBI Entrez Gene ID: 1215  
ASDInformation of known allosteric effects of PDB entries
 
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