Browse entries in the PDBbind-CN Database
HEADER TRANSCRIPTION/DNA 07-MAR-18 5ZFZ TITLE CRYSTAL STRUCTURE OF HUMAN DUX4 HOMEODOMAINS BOUND TO A12T DNA MUTANT COMPND MOL_ID: 1; COMPND 2 MOLECULE: DOUBLE HOMEOBOX PROTEIN 4-LIKE PROTEIN 4; COMPND 3 CHAIN: A; COMPND 4 FRAGMENT: DOUBLE HOMEODOMAINS; COMPND 5 SYNONYM: DUX4; COMPND 6 ENGINEERED: YES; COMPND 7 MOL_ID: 2; COMPND 8 MOLECULE: DNA (5'- COMPND 9 D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'); COMPND 10 CHAIN: D; COMPND 11 ENGINEERED: YES; COMPND 12 MOL_ID: 3; COMPND 13 MOLECULE: DNA (5'- COMPND 14 D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'); COMPND 15 CHAIN: E; COMPND 16 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: DUX4L4; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 MOL_ID: 2; SOURCE 9 SYNTHETIC: YES; SOURCE 10 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 11 ORGANISM_TAXID: 32630; SOURCE 12 MOL_ID: 3; SOURCE 13 SYNTHETIC: YES; SOURCE 14 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 15 ORGANISM_TAXID: 32630 KEYWDS HOMEODOMAINS, DUX4, DNA RECOGNITION, TRANSCRIPTION-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR Y.Y.LI,B.X.WU,J.H.GAN REVDAT 2 14-NOV-18 5ZFZ 1 JRNL REVDAT 1 31-OCT-18 5ZFZ 0 JRNL AUTH Y.LI,B.WU,H.LIU,Y.GAO,C.YANG,X.CHEN,J.ZHANG,Y.CHEN,Y.GU, JRNL AUTH 2 J.LI,J.MA,J.GAN JRNL TITL STRUCTURAL BASIS FOR MULTIPLE GENE REGULATION BY HUMAN DUX4. JRNL REF BIOCHEM. BIOPHYS. RES. V. 505 1161 2018 JRNL REF 2 COMMUN. JRNL REFN ESSN 1090-2104 JRNL PMID 30322619 JRNL DOI 10.1016/J.BBRC.2018.10.056 REMARK 2 REMARK 2 RESOLUTION. 1.90 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : PHENIX (1.10.1_2155) REMARK 3 AUTHORS : PAUL ADAMS,PAVEL AFONINE,VINCENT CHEN,IAN REMARK 3 : DAVIS,KRESHNA GOPAL,RALF GROSSE-KUNSTLEVE, REMARK 3 : LI-WEI HUNG,ROBERT IMMORMINO,TOM IOERGER, REMARK 3 : AIRLIE MCCOY,ERIK MCKEE,NIGEL MORIARTY, REMARK 3 : REETAL PAI,RANDY READ,JANE RICHARDSON, REMARK 3 : DAVID RICHARDSON,TOD ROMO,JIM SACCHETTINI, REMARK 3 : NICHOLAS SAUTER,JACOB SMITH,LAURENT REMARK 3 : STORONI,TOM TERWILLIGER,PETER ZWART REMARK 3 REMARK 3 REFINEMENT TARGET : NULL REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.90 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 29.88 REMARK 3 MIN(FOBS/SIGMA_FOBS) : 1.510 REMARK 3 COMPLETENESS FOR RANGE (%) : 88.0 REMARK 3 NUMBER OF REFLECTIONS : 26645 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 R VALUE (WORKING + TEST SET) : 0.188 REMARK 3 R VALUE (WORKING SET) : 0.186 REMARK 3 FREE R VALUE : 0.221 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 5.140 REMARK 3 FREE R VALUE TEST SET COUNT : 1370 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT (IN BINS). REMARK 3 BIN RESOLUTION RANGE COMPL. NWORK NFREE RWORK RFREE REMARK 3 1 29.8808 - 4.0814 1.00 3059 171 0.1562 0.1716 REMARK 3 2 4.0814 - 3.2408 1.00 2919 151 0.1448 0.1642 REMARK 3 3 3.2408 - 2.8315 1.00 2876 158 0.1783 0.2318 REMARK 3 4 2.8315 - 2.5727 1.00 2868 157 0.2063 0.2686 REMARK 3 5 2.5727 - 2.3884 1.00 2818 166 0.1952 0.2572 REMARK 3 6 2.3884 - 2.2477 1.00 2834 151 0.2016 0.2412 REMARK 3 7 2.2477 - 2.1351 0.98 2830 149 0.2322 0.2750 REMARK 3 8 2.1351 - 2.0422 0.85 2403 125 0.2482 0.3038 REMARK 3 9 2.0422 - 1.9636 0.62 1736 110 0.2596 0.3005 REMARK 3 10 1.9636 - 1.8959 0.32 932 32 0.2751 0.2853 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : NULL REMARK 3 SOLVENT RADIUS : 1.11 REMARK 3 SHRINKAGE RADIUS : 0.90 REMARK 3 K_SOL : NULL REMARK 3 B_SOL : NULL REMARK 3 REMARK 3 ERROR ESTIMATES. REMARK 3 COORDINATE ERROR (MAXIMUM-LIKELIHOOD BASED) : 0.220 REMARK 3 PHASE ERROR (DEGREES, MAXIMUM-LIKELIHOOD BASED) : 21.030 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : NULL REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : NULL REMARK 3 B22 (A**2) : NULL REMARK 3 B33 (A**2) : NULL REMARK 3 B12 (A**2) : NULL REMARK 3 B13 (A**2) : NULL REMARK 3 B23 (A**2) : NULL REMARK 3 REMARK 3 TWINNING INFORMATION. REMARK 3 FRACTION: NULL REMARK 3 OPERATOR: NULL REMARK 3 REMARK 3 DEVIATIONS FROM IDEAL VALUES. REMARK 3 RMSD COUNT REMARK 3 BOND : 0.009 1907 REMARK 3 ANGLE : 0.992 2730 REMARK 3 CHIRALITY : 0.051 290 REMARK 3 PLANARITY : 0.007 227 REMARK 3 DIHEDRAL : 26.837 1022 REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 1 REMARK 3 TLS GROUP : 1 REMARK 3 SELECTION: ALL REMARK 3 ORIGIN FOR THE GROUP (A): -37.7334 14.5991 164.5078 REMARK 3 T TENSOR REMARK 3 T11: 0.1329 T22: 0.0836 REMARK 3 T33: 0.1048 T12: 0.0141 REMARK 3 T13: 0.0057 T23: -0.0465 REMARK 3 L TENSOR REMARK 3 L11: 0.1979 L22: 0.5198 REMARK 3 L33: 0.3684 L12: -0.0217 REMARK 3 L13: 0.0376 L23: 0.0531 REMARK 3 S TENSOR REMARK 3 S11: 0.0089 S12: 0.0328 S13: -0.0838 REMARK 3 S21: 0.0987 S22: 0.0175 S23: 0.0078 REMARK 3 S31: 0.0558 S32: 0.0018 S33: 0.0525 REMARK 3 REMARK 3 NCS DETAILS REMARK 3 NUMBER OF NCS GROUPS : NULL REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: NULL REMARK 4 REMARK 4 5ZFZ COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 13-MAR-18. REMARK 100 THE DEPOSITION ID IS D_1300007006. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 27-JAN-18 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 4.0 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : SSRF REMARK 200 BEAMLINE : BL18U1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.977776 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : HKL-3000 REMARK 200 DATA SCALING SOFTWARE : HKL-3000 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 29905 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.900 REMARK 200 RESOLUTION RANGE LOW (A) : 30.000 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 98.7 REMARK 200 DATA REDUNDANCY : 12.60 REMARK 200 R MERGE (I) : NULL REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 39.6400 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.90 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.97 REMARK 200 COMPLETENESS FOR SHELL (%) : NULL REMARK 200 DATA REDUNDANCY IN SHELL : NULL REMARK 200 R MERGE FOR SHELL (I) : NULL REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: 5Z6Z REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 61.40 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 3.19 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 0.1 M SODIUM MALONATE PH 4.0, 12% REMARK 280 POLYETHYLENE GLYCOL 3350, VAPOR DIFFUSION, SITTING DROP, REMARK 280 TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 32 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -Y,X-Y,Z+2/3 REMARK 290 3555 -X+Y,-X,Z+1/3 REMARK 290 4555 Y,X,-Z REMARK 290 5555 X-Y,-Y,-Z+1/3 REMARK 290 6555 -X,-X+Y,-Z+2/3 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 2 0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 1.000000 101.10733 REMARK 290 SMTRY1 3 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 3 -0.866025 -0.500000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 50.55367 REMARK 290 SMTRY1 4 -0.500000 0.866025 0.000000 0.00000 REMARK 290 SMTRY2 4 0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 5 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 5 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 5 0.000000 0.000000 -1.000000 50.55367 REMARK 290 SMTRY1 6 -0.500000 -0.866025 0.000000 0.00000 REMARK 290 SMTRY2 6 -0.866025 0.500000 0.000000 0.00000 REMARK 290 SMTRY3 6 0.000000 0.000000 -1.000000 101.10733 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TRIMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 5720 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 12020 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -20.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, D, E REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 375 REMARK 375 SPECIAL POSITION REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL REMARK 375 POSITIONS. REMARK 375 REMARK 375 ATOM RES CSSEQI REMARK 375 HOH A 326 LIES ON A SPECIAL POSITION. REMARK 375 HOH A 330 LIES ON A SPECIAL POSITION. REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 1 REMARK 465 ALA A 2 REMARK 465 LEU A 3 REMARK 465 PRO A 4 REMARK 465 THR A 5 REMARK 465 PRO A 6 REMARK 465 SER A 7 REMARK 465 ASP A 8 REMARK 465 SER A 9 REMARK 465 THR A 10 REMARK 465 LEU A 11 REMARK 465 PRO A 12 REMARK 465 ALA A 13 REMARK 465 GLU A 14 REMARK 465 ALA A 15 REMARK 465 ARG A 16 REMARK 465 GLY A 17 REMARK 465 ARG A 18 REMARK 465 ARG A 83 REMARK 465 PRO A 84 REMARK 465 TRP A 85 REMARK 465 PRO A 86 REMARK 465 GLY A 87 REMARK 465 ARG A 88 REMARK 465 ARG A 89 REMARK 465 GLY A 90 REMARK 465 PRO A 91 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT REMARK 500 REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT. REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE REMARK 500 O HOH A 302 O HOH A 325 2.10 REMARK 500 O HOH A 247 O HOH A 312 2.11 REMARK 500 OP2 DC D 9 O HOH D 101 2.17 REMARK 500 O HOH D 122 O HOH E 156 2.18 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION REMARK 500 DT E 5 O3' DT E 5 C3' -0.044 REMARK 500 DA E 8 O3' DA E 8 C3' -0.041 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DC D 8 O4' - C1' - N1 ANGL. DEV. = 2.3 DEGREES REMARK 500 DC D 16 O4' - C1' - N1 ANGL. DEV. = 2.7 DEGREES REMARK 500 DT E 5 O4' - C1' - N1 ANGL. DEV. = 3.4 DEGREES REMARK 500 DG E 11 O4' - C1' - N9 ANGL. DEV. = 4.1 DEGREES REMARK 500 DG E 18 O4' - C1' - N9 ANGL. DEV. = 2.7 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 ASN A 41 109.10 -164.23 REMARK 500 REMARK 500 REMARK: NULL REMARK 525 REMARK 525 SOLVENT REMARK 525 REMARK 525 THE SOLVENT MOLECULES HAVE CHAIN IDENTIFIERS THAT REMARK 525 INDICATE THE POLYMER CHAIN WITH WHICH THEY ARE MOST REMARK 525 CLOSELY ASSOCIATED. THE REMARK LISTS ALL THE SOLVENT REMARK 525 MOLECULES WHICH ARE MORE THAN 5A AWAY FROM THE REMARK 525 NEAREST POLYMER CHAIN (M = MODEL NUMBER; REMARK 525 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE REMARK 525 NUMBER; I=INSERTION CODE): REMARK 525 REMARK 525 M RES CSSEQI REMARK 525 HOH A 351 DISTANCE = 5.87 ANGSTROMS DBREF 5ZFZ A 1 149 UNP P0CJ87 DU4L4_HUMAN 1 149 DBREF 5ZFZ D 1 19 PDB 5ZFZ 5ZFZ 1 19 DBREF 5ZFZ E 1 19 PDB 5ZFZ 5ZFZ 1 19 SEQRES 1 A 149 MET ALA LEU PRO THR PRO SER ASP SER THR LEU PRO ALA SEQRES 2 A 149 GLU ALA ARG GLY ARG GLY ARG ARG ARG ARG LEU VAL TRP SEQRES 3 A 149 THR PRO SER GLN SER GLU ALA LEU ARG ALA CYS PHE GLU SEQRES 4 A 149 ARG ASN PRO TYR PRO GLY ILE ALA THR ARG GLU ARG LEU SEQRES 5 A 149 ALA GLN ALA ILE GLY ILE PRO GLU PRO ARG VAL GLN ILE SEQRES 6 A 149 TRP PHE GLN ASN GLU ARG SER ARG GLN LEU ARG GLN HIS SEQRES 7 A 149 ARG ARG GLU SER ARG PRO TRP PRO GLY ARG ARG GLY PRO SEQRES 8 A 149 PRO GLU GLY ARG ARG LYS ARG THR ALA VAL THR GLY SER SEQRES 9 A 149 GLN THR ALA LEU LEU LEU ARG ALA PHE GLU LYS ASP ARG SEQRES 10 A 149 PHE PRO GLY ILE ALA ALA ARG GLU GLU LEU ALA ARG GLU SEQRES 11 A 149 THR GLY LEU PRO GLU SER ARG ILE GLN ILE TRP PHE GLN SEQRES 12 A 149 ASN ARG ARG ALA ARG HIS SEQRES 1 D 19 DC DC DA DC DT DA DA DC DC DT DA DT DT SEQRES 2 D 19 DC DA DC DA DC DC SEQRES 1 E 19 DG DG DT DG DT DG DA DA DT DA DG DG DT SEQRES 2 E 19 DT DA DG DT DG DG FORMUL 4 HOH *265(H2 O) HELIX 1 AA1 THR A 27 ASN A 41 1 15 HELIX 2 AA2 GLY A 45 GLY A 57 1 13 HELIX 3 AA3 PRO A 59 SER A 82 1 24 HELIX 4 AA4 THR A 102 ASP A 116 1 15 HELIX 5 AA5 GLY A 120 GLY A 132 1 13 HELIX 6 AA6 PRO A 134 HIS A 149 1 16 CRYST1 65.013 65.013 151.661 90.00 90.00 120.00 P 32 2 1 6 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.015382 0.008881 0.000000 0.00000 SCALE2 0.000000 0.017761 0.000000 0.00000 SCALE3 0.000000 0.000000 0.006594 0.00000 ATOM 1 N GLY A 19 -33.982 19.293 180.486 1.00 27.91 N ANISOU 1 N GLY A 19 4414 3033 3159 216 -56 -282 N ATOM 2 CA GLY A 19 -34.077 20.614 179.870 1.00 27.52 C ANISOU 2 CA GLY A 19 4331 3012 3113 209 -43 -293 C ATOM 3 C GLY A 19 -34.142 20.569 178.349 1.00 24.71 C ANISOU 3 C GLY A 19 3899 2691 2801 201 -34 -308 C ATOM 4 O GLY A 19 -33.344 19.889 177.717 1.00 29.01 O ANISOU 4 O GLY A 19 4407 3242 3372 205 -64 -321 O ATOM 5 N ARG A 20 -35.084 21.286 177.747 1.00 19.42 N ANISOU 5 N ARG A 20 3203 2040 2134 192 7 -308 N ATOM 6 CA ARG A 20 -35.264 21.240 176.307 1.00 19.88 C ANISOU 6 CA ARG A 20 3195 2130 2229 185 18 -321 C ATOM 7 C ARG A 20 -34.817 22.551 175.677 1.00 26.62 C ANISOU 7 C ARG A 20 4021 3009 3083 182 10 -333 C ATOM 8 O ARG A 20 -34.663 23.571 176.353 1.00 21.07 O ANISOU 8 O ARG A 20 3352 2300 2355 183 6 -328 O ATOM 9 CB ARG A 20 -36.720 20.927 175.947 1.00 20.45 C ANISOU 9 CB ARG A 20 3253 2208 2311 178 68 -313 C ATOM 10 CG ARG A 20 -37.764 21.853 176.520 1.00 28.69 C ANISOU 10 CG ARG A 20 4323 3247 3329 176 108 -300 C ATOM 11 CD ARG A 20 -39.160 21.516 175.964 1.00 26.49 C ANISOU 11 CD ARG A 20 4015 2979 3070 169 154 -295 C ATOM 12 NE ARG A 20 -39.507 20.110 176.157 1.00 26.60 N ANISOU 12 NE ARG A 20 4034 2975 3096 164 161 -288 N ATOM 13 CZ ARG A 20 -40.502 19.485 175.529 1.00 18.98 C ANISOU 13 CZ ARG A 20 3036 2017 2157 154 190 -287 C ATOM 14 NH1 ARG A 20 -41.258 20.133 174.650 1.00 21.42 N ANISOU 14 NH1 ARG A 20 3302 2354 2483 150 212 -293 N ATOM 15 NH2 ARG A 20 -40.737 18.202 175.766 1.00 23.65 N ANISOU 15 NH2 ARG A 20 3638 2588 2760 147 194 -281 N ATOM 16 N ARG A 21 -34.573 22.518 174.367 1.00 18.50 N ANISOU 16 N ARG A 21 2935 2009 2085 177 7 -347 N ATOM 17 CA ARG A 21 -34.114 23.735 173.706 1.00 27.21 C ANISOU 17 CA ARG A 21 4013 3136 3190 171 1 -357 C ATOM 18 C ARG A 21 -35.169 24.838 173.831 1.00 20.35 C ANISOU 18 C ARG A 21 3159 2269 2302 168 37 -346 C ATOM 19 O ARG A 21 -36.353 24.582 174.065 1.00 16.00 O ANISOU 19 O ARG A 21 2620 1712 1747 170 72 -335 O ATOM 20 CB ARG A 21 -33.767 23.450 172.243 1.00 26.85 C ANISOU 20 CB ARG A 21 3906 3119 3177 166 -2 -373 C ATOM 21 CG ARG A 21 -34.869 23.685 171.270 1.00 28.16 C ANISOU 21 CG ARG A 21 4042 3304 3352 160 33 -372 C ATOM 22 CD ARG A 21 -34.634 22.934 169.943 1.00 30.92 C ANISOU 22 CD ARG A 21 4340 3676 3732 158 29 -388 C ATOM 23 NE ARG A 21 -33.293 23.118 169.406 1.00 31.52 N ANISOU 23 NE ARG A 21 4391 3767 3819 157 1 -404 N ATOM 24 CZ ARG A 21 -32.422 22.132 169.224 1.00 28.48 C ANISOU 24 CZ ARG A 21 3988 3381 3453 162 -23 -416 C ATOM 25 NH1 ARG A 21 -31.220 22.405 168.722 1.00 24.84 N ANISOU 25 NH1 ARG A 21 3499 2935 3003 161 -46 -431 N ATOM 26 NH2 ARG A 21 -32.758 20.871 169.521 1.00 28.17 N ANISOU 26 NH2 ARG A 21 3958 3324 3422 169 -24 -415 N ATOM 27 N ARG A 22 -34.725 26.083 173.709 1.00 22.70 N ANISOU 27 N ARG A 22 3458 2575 2590 164 28 -350 N ATOM 28 CA ARG A 22 -35.638 27.202 173.890 1.00 27.86 C ANISOU 28 CA ARG A 22 4125 3232 3229 163 58 -338 C ATOM 29 C ARG A 22 -36.516 27.339 172.655 1.00 25.84 C ANISOU 29 C ARG A 22 3828 2999 2990 161 87 -343 C ATOM 30 O ARG A 22 -36.019 27.395 171.524 1.00 28.98 O ANISOU 30 O ARG A 22 4186 3418 3406 155 76 -355 O ATOM 31 CB ARG A 22 -34.871 28.494 174.172 1.00 29.93 C ANISOU 31 CB ARG A 22 4401 3495 3477 157 38 -338 C ATOM 32 CG ARG A 22 -35.718 29.757 174.096 1.00 46.25 C ANISOU 32 CG ARG A 22 6471 5568 5534 156 65 -327 C ATOM 33 CD ARG A 22 -35.125 30.869 174.964 1.00 58.10 C ANISOU 33 CD ARG A 22 8007 7056 7013 152 46 -321 C ATOM 34 NE ARG A 22 -33.679 30.959 174.806 1.00 65.72 N ANISOU 34 NE ARG A 22 8965 8021 7984 143 5 -336 N ATOM 35 CZ ARG A 22 -32.847 31.403 175.743 1.00 72.07 C ANISOU 35 CZ ARG A 22 9802 8809 8772 140 -25 -335 C ATOM 36 NH1 ARG A 22 -33.315 31.802 176.922 1.00 72.65 N ANISOU 36 NH1 ARG A 22 9920 8864 8820 146 -18 -319 N ATOM 37 NH2 ARG A 22 -31.539 31.438 175.503 1.00 75.18 N ANISOU 37 NH2 ARG A 22 10183 9205 9176 131 -64 -351 N ATOM 38 N ARG A 23 -37.824 27.375 172.885 1.00 22.35 N ANISOU 38 N ARG A 23 3393 2554 2544 166 123 -330 N ATOM 39 CA ARG A 23 -38.817 27.312 171.824 1.00 13.06 C ANISOU 39 CA ARG A 23 2179 1396 1385 166 150 -334 C ATOM 40 C ARG A 23 -38.791 28.574 170.963 1.00 21.44 C ANISOU 40 C ARG A 23 3222 2478 2448 164 150 -337 C ATOM 41 O ARG A 23 -38.842 29.688 171.482 1.00 21.62 O ANISOU 41 O ARG A 23 3265 2496 2455 166 152 -327 O ATOM 42 CB ARG A 23 -40.180 27.117 172.476 1.00 18.21 C ANISOU 42 CB ARG A 23 2849 2038 2033 172 189 -321 C ATOM 43 CG ARG A 23 -41.358 27.218 171.573 1.00 21.78 C ANISOU 43 CG ARG A 23 3261 2509 2505 173 216 -321 C ATOM 44 CD ARG A 23 -42.632 26.906 172.348 1.00 17.35 C ANISOU 44 CD ARG A 23 2716 1936 1942 178 256 -308 C ATOM 45 NE ARG A 23 -43.810 27.147 171.513 1.00 14.61 N ANISOU 45 NE ARG A 23 2327 1608 1615 181 280 -308 N ATOM 46 CZ ARG A 23 -44.888 26.378 171.519 1.00 8.62 C ANISOU 46 CZ ARG A 23 1548 850 876 178 307 -304 C ATOM 47 NH1 ARG A 23 -44.943 25.311 172.309 1.00 8.77 N ANISOU 47 NH1 ARG A 23 1588 850 895 171 316 -298 N ATOM 48 NH2 ARG A 23 -45.911 26.668 170.717 1.00 16.08 N ANISOU 48 NH2 ARG A 23 2453 1814 1842 181 324 -306 N ATOM 49 N LEU A 24 -38.684 28.401 169.647 1.00 24.77 N ANISOU 49 N LEU A 24 3599 2924 2890 159 145 -347 N ATOM 50 CA LEU A 24 -38.745 29.528 168.728 1.00 21.06 C ANISOU 50 CA LEU A 24 3112 2470 2418 158 147 -349 C ATOM 51 C LEU A 24 -40.160 30.073 168.620 1.00 18.84 C ANISOU 51 C LEU A 24 2830 2192 2136 168 178 -340 C ATOM 52 O LEU A 24 -41.143 29.371 168.865 1.00 18.73 O ANISOU 52 O LEU A 24 2810 2176 2132 173 199 -335 O ATOM 53 CB LEU A 24 -38.332 29.126 167.316 1.00 23.93 C ANISOU 53 CB LEU A 24 3430 2860 2802 150 135 -361 C ATOM 54 CG LEU A 24 -36.936 28.679 166.947 1.00 41.40 C ANISOU 54 CG LEU A 24 5627 5080 5023 140 107 -374 C ATOM 55 CD1 LEU A 24 -36.993 28.300 165.492 1.00 40.46 C ANISOU 55 CD1 LEU A 24 5465 4984 4924 137 108 -385 C ATOM 56 CD2 LEU A 24 -35.947 29.807 167.163 1.00 49.54 C ANISOU 56 CD2 LEU A 24 6667 6115 6043 132 94 -376 C ATOM 57 N VAL A 25 -40.251 31.314 168.140 1.00 15.17 N ANISOU 57 N VAL A 25 2367 1734 1662 171 180 -338 N ATOM 58 CA VAL A 25 -41.510 31.960 167.790 1.00 14.06 C ANISOU 58 CA VAL A 25 2218 1599 1523 183 205 -331 C ATOM 59 C VAL A 25 -41.380 32.469 166.358 1.00 17.08 C ANISOU 59 C VAL A 25 2571 2004 1913 179 194 -336 C ATOM 60 O VAL A 25 -40.474 33.257 166.065 1.00 15.23 O ANISOU 60 O VAL A 25 2349 1771 1668 171 178 -338 O ATOM 61 CB VAL A 25 -41.842 33.109 168.761 1.00 23.32 C ANISOU 61 CB VAL A 25 3425 2757 2680 190 214 -317 C ATOM 62 CG1 VAL A 25 -43.057 33.906 168.285 1.00 20.84 C ANISOU 62 CG1 VAL A 25 3100 2448 2368 206 236 -312 C ATOM 63 CG2 VAL A 25 -42.090 32.547 170.172 1.00 24.75 C ANISOU 63 CG2 VAL A 25 3632 2919 2855 193 226 -308 C ATOM 64 N TRP A 26 -42.251 31.998 165.458 1.00 12.70 N ANISOU 64 N TRP A 26 1981 1469 1377 183 202 -338 N ATOM 65 CA TRP A 26 -42.139 32.402 164.058 1.00 17.87 C ANISOU 65 CA TRP A 26 2610 2145 2035 180 191 -343 C ATOM 66 C TRP A 26 -42.531 33.858 163.884 1.00 19.56 C ANISOU 66 C TRP A 26 2843 2355 2235 190 197 -334 C ATOM 67 O TRP A 26 -43.448 34.346 164.546 1.00 16.93 O ANISOU 67 O TRP A 26 2524 2010 1898 206 215 -326 O ATOM 68 CB TRP A 26 -43.038 31.562 163.147 1.00 13.50 C ANISOU 68 CB TRP A 26 2016 1611 1503 182 194 -348 C ATOM 69 CG TRP A 26 -43.023 30.088 163.401 1.00 12.29 C ANISOU 69 CG TRP A 26 1847 1457 1368 174 194 -355 C ATOM 70 CD1 TRP A 26 -44.071 29.327 163.843 1.00 15.93 C ANISOU 70 CD1 TRP A 26 2296 1913 1845 178 210 -353 C ATOM 71 CD2 TRP A 26 -41.921 29.195 163.231 1.00 13.18 C ANISOU 71 CD2 TRP A 26 1952 1571 1484 161 176 -366 C ATOM 72 NE1 TRP A 26 -43.688 28.011 163.954 1.00 12.04 N ANISOU 72 NE1 TRP A 26 1792 1417 1364 168 204 -361 N ATOM 73 CE2 TRP A 26 -42.370 27.906 163.588 1.00 14.98 C ANISOU 73 CE2 TRP A 26 2168 1793 1730 159 182 -370 C ATOM 74 CE3 TRP A 26 -40.595 29.357 162.811 1.00 21.70 C ANISOU 74 CE3 TRP A 26 3033 2656 2555 152 158 -374 C ATOM 75 CZ2 TRP A 26 -41.536 26.785 163.540 1.00 20.68 C ANISOU 75 CZ2 TRP A 26 2883 2513 2460 150 167 -380 C ATOM 76 CZ3 TRP A 26 -39.773 28.253 162.765 1.00 30.07 C ANISOU 76 CZ3 TRP A 26 4082 3718 3627 144 144 -386 C ATOM 77 CH2 TRP A 26 -40.243 26.981 163.129 1.00 29.18 C ANISOU 77 CH2 TRP A 26 3961 3598 3530 145 148 -389 C ATOM 78 N THR A 27 -41.859 34.533 162.961 1.00 17.81 N ANISOU 78 N THR A 27 2620 2143 2004 183 182 -335 N ATOM 79 CA THR A 27 -42.323 35.802 162.436 1.00 17.26 C ANISOU 79 CA THR A 27 2563 2073 1924 193 185 -327 C ATOM 80 C THR A 27 -43.398 35.545 161.393 1.00 26.89 C ANISOU 80 C THR A 27 3749 3312 3156 204 187 -327 C ATOM 81 O THR A 27 -43.486 34.446 160.848 1.00 20.67 O ANISOU 81 O THR A 27 2929 2541 2383 198 182 -336 O ATOM 82 CB THR A 27 -41.177 36.577 161.781 1.00 17.03 C ANISOU 82 CB THR A 27 2545 2046 1879 177 170 -327 C ATOM 83 OG1 THR A 27 -40.698 35.838 160.657 1.00 14.16 O ANISOU 83 OG1 THR A 27 2151 1707 1524 164 160 -336 O ATOM 84 CG2 THR A 27 -40.026 36.806 162.753 1.00 20.05 C ANISOU 84 CG2 THR A 27 2956 2411 2252 163 163 -329 C ATOM 85 N PRO A 28 -44.228 36.545 161.087 1.00 26.46 N ANISOU 85 N PRO A 28 3702 3255 3096 222 192 -318 N ATOM 86 CA PRO A 28 -45.228 36.341 160.024 1.00 22.83 C ANISOU 86 CA PRO A 28 3210 2815 2649 233 187 -319 C ATOM 87 C PRO A 28 -44.609 35.938 158.696 1.00 21.77 C ANISOU 87 C PRO A 28 3058 2703 2512 218 169 -327 C ATOM 88 O PRO A 28 -45.136 35.059 158.001 1.00 16.56 O ANISOU 88 O PRO A 28 2365 2060 1867 218 162 -335 O ATOM 89 CB PRO A 28 -45.937 37.700 159.953 1.00 23.25 C ANISOU 89 CB PRO A 28 3284 2858 2693 256 191 -307 C ATOM 90 CG PRO A 28 -45.809 38.254 161.333 1.00 23.04 C ANISOU 90 CG PRO A 28 3291 2805 2657 261 208 -302 C ATOM 91 CD PRO A 28 -44.484 37.768 161.871 1.00 24.89 C ANISOU 91 CD PRO A 28 3540 3033 2883 236 202 -308 C ATOM 92 N SER A 29 -43.469 36.522 158.345 1.00 15.52 N ANISOU 92 N SER A 29 2287 1909 1701 203 161 -326 N ATOM 93 CA SER A 29 -42.816 36.152 157.098 1.00 15.46 C ANISOU 93 CA SER A 29 2265 1922 1688 188 148 -333 C ATOM 94 C SER A 29 -42.343 34.702 157.112 1.00 13.21 C ANISOU 94 C SER A 29 1953 1648 1419 175 145 -349 C ATOM 95 O SER A 29 -42.354 34.018 156.079 1.00 15.92 O ANISOU 95 O SER A 29 2273 2011 1765 171 137 -359 O ATOM 96 CB SER A 29 -41.631 37.083 156.849 1.00 17.58 C ANISOU 96 CB SER A 29 2561 2184 1935 172 145 -328 C ATOM 97 OG SER A 29 -40.802 36.514 155.865 1.00 28.41 O ANISOU 97 OG SER A 29 3916 3576 3304 155 138 -339 O ATOM 98 N GLN A 30 -41.862 34.228 158.254 1.00 13.67 N ANISOU 98 N GLN A 30 2017 1693 1485 169 151 -352 N ATOM 99 CA GLN A 30 -41.428 32.839 158.316 1.00 8.49 C ANISOU 99 CA GLN A 30 1337 1044 843 159 147 -366 C ATOM 100 C GLN A 30 -42.623 31.902 158.218 1.00 9.78 C ANISOU 100 C GLN A 30 1475 1215 1028 169 150 -370 C ATOM 101 O GLN A 30 -42.584 30.924 157.469 1.00 15.63 O ANISOU 101 O GLN A 30 2191 1970 1778 163 142 -383 O ATOM 102 CB GLN A 30 -40.637 32.604 159.609 1.00 15.69 C ANISOU 102 CB GLN A 30 2266 1937 1757 153 149 -366 C ATOM 103 CG GLN A 30 -39.284 33.318 159.621 1.00 13.09 C ANISOU 103 CG GLN A 30 1956 1605 1414 138 142 -366 C ATOM 104 CD GLN A 30 -38.629 33.338 160.976 1.00 12.44 C ANISOU 104 CD GLN A 30 1896 1502 1331 134 140 -364 C ATOM 105 OE1 GLN A 30 -39.304 33.295 162.009 1.00 15.99 O ANISOU 105 OE1 GLN A 30 2361 1934 1781 145 148 -358 O ATOM 106 NE2 GLN A 30 -37.306 33.391 160.984 1.00 18.16 N ANISOU 106 NE2 GLN A 30 2620 2226 2052 118 129 -371 N ATOM 107 N SER A 31 -43.705 32.194 158.951 1.00 8.87 N ANISOU 107 N SER A 31 1364 1088 919 183 163 -360 N ATOM 108 CA SER A 31 -44.896 31.348 158.870 1.00 14.32 C ANISOU 108 CA SER A 31 2025 1784 1632 190 167 -364 C ATOM 109 C SER A 31 -45.418 31.274 157.445 1.00 14.71 C ANISOU 109 C SER A 31 2049 1855 1684 193 152 -370 C ATOM 110 O SER A 31 -45.791 30.198 156.964 1.00 12.62 O ANISOU 110 O SER A 31 1757 1601 1436 188 145 -382 O ATOM 111 CB SER A 31 -45.987 31.872 159.795 1.00 21.83 C ANISOU 111 CB SER A 31 2983 2722 2589 207 186 -352 C ATOM 112 OG SER A 31 -45.650 31.593 161.134 1.00 29.29 O ANISOU 112 OG SER A 31 3948 3647 3533 203 201 -348 O ATOM 113 N GLU A 32 -45.433 32.407 156.741 1.00 12.94 N ANISOU 113 N GLU A 32 1838 1637 1442 201 145 -363 N ATOM 114 CA GLU A 32 -45.954 32.393 155.380 1.00 14.72 C ANISOU 114 CA GLU A 32 2045 1882 1665 205 128 -368 C ATOM 115 C GLU A 32 -45.118 31.496 154.483 1.00 12.99 C ANISOU 115 C GLU A 32 1816 1678 1443 188 116 -383 C ATOM 116 O GLU A 32 -45.660 30.715 153.693 1.00 16.00 O ANISOU 116 O GLU A 32 2172 2073 1833 188 104 -395 O ATOM 117 CB GLU A 32 -46.003 33.807 154.807 1.00 10.42 C ANISOU 117 CB GLU A 32 1525 1338 1098 216 122 -355 C ATOM 118 CG GLU A 32 -46.677 33.831 153.444 1.00 14.95 C ANISOU 118 CG GLU A 32 2083 1930 1668 224 102 -358 C ATOM 119 CD GLU A 32 -46.431 35.117 152.678 1.00 26.40 C ANISOU 119 CD GLU A 32 3563 3380 3089 231 94 -346 C ATOM 120 OE1 GLU A 32 -45.936 36.077 153.302 1.00 27.26 O ANISOU 120 OE1 GLU A 32 3701 3472 3185 231 105 -334 O ATOM 121 OE2 GLU A 32 -46.738 35.159 151.459 1.00 19.35 O ANISOU 121 OE2 GLU A 32 2666 2502 2185 235 75 -349 O ATOM 122 N ALA A 33 -43.798 31.605 154.571 1.00 7.92 N ANISOU 122 N ALA A 33 1191 1033 786 175 119 -386 N ATOM 123 CA ALA A 33 -42.936 30.794 153.718 1.00 12.65 C ANISOU 123 CA ALA A 33 1779 1646 1380 161 111 -402 C ATOM 124 C ALA A 33 -43.085 29.308 154.033 1.00 11.40 C ANISOU 124 C ALA A 33 1597 1487 1246 156 110 -417 C ATOM 125 O ALA A 33 -43.107 28.476 153.121 1.00 10.68 O ANISOU 125 O ALA A 33 1489 1410 1158 152 99 -432 O ATOM 126 CB ALA A 33 -41.479 31.233 153.880 1.00 8.10 C ANISOU 126 CB ALA A 33 1222 1067 789 147 117 -401 C ATOM 127 N LEU A 34 -43.178 28.954 155.320 1.00 9.45 N ANISOU 127 N LEU A 34 1353 1223 1015 156 120 -412 N ATOM 128 CA LEU A 34 -43.364 27.550 155.684 1.00 9.98 C ANISOU 128 CA LEU A 34 1402 1285 1106 151 120 -424 C ATOM 129 C LEU A 34 -44.654 26.996 155.091 1.00 9.19 C ANISOU 129 C LEU A 34 1276 1194 1023 155 113 -430 C ATOM 130 O LEU A 34 -44.657 25.944 154.436 1.00 8.56 O ANISOU 130 O LEU A 34 1178 1121 953 148 102 -446 O ATOM 131 CB LEU A 34 -43.360 27.407 157.207 1.00 7.71 C ANISOU 131 CB LEU A 34 1127 975 828 152 134 -414 C ATOM 132 CG LEU A 34 -42.015 27.673 157.886 1.00 21.54 C ANISOU 132 CG LEU A 34 2902 2716 2567 146 135 -413 C ATOM 133 CD1 LEU A 34 -42.222 27.927 159.348 1.00 7.59 C ANISOU 133 CD1 LEU A 34 1156 926 801 150 148 -399 C ATOM 134 CD2 LEU A 34 -41.045 26.501 157.672 1.00 14.81 C ANISOU 134 CD2 LEU A 34 2038 1865 1723 137 125 -430 C ATOM 135 N ARG A 35 -45.760 27.706 155.302 1.00 12.01 N ANISOU 135 N ARG A 35 1630 1550 1385 167 118 -417 N ATOM 136 CA ARG A 35 -47.061 27.264 154.795 1.00 14.92 C ANISOU 136 CA ARG A 35 1969 1927 1773 171 110 -422 C ATOM 137 C ARG A 35 -47.083 27.188 153.270 1.00 10.93 C ANISOU 137 C ARG A 35 1454 1443 1257 171 86 -434 C ATOM 138 O ARG A 35 -47.629 26.238 152.696 1.00 11.93 O ANISOU 138 O ARG A 35 1557 1576 1399 165 73 -448 O ATOM 139 CB ARG A 35 -48.151 28.206 155.316 1.00 8.84 C ANISOU 139 CB ARG A 35 1196 1153 1009 188 121 -406 C ATOM 140 CG ARG A 35 -48.228 28.247 156.814 1.00 10.06 C ANISOU 140 CG ARG A 35 1363 1286 1172 189 146 -394 C ATOM 141 CD ARG A 35 -49.513 28.901 157.300 1.00 22.16 C ANISOU 141 CD ARG A 35 2885 2816 2719 206 160 -383 C ATOM 142 NE ARG A 35 -49.628 28.862 158.758 1.00 30.65 N ANISOU 142 NE ARG A 35 3973 3871 3800 207 189 -373 N ATOM 143 CZ ARG A 35 -50.311 27.928 159.433 1.00 41.77 C ANISOU 143 CZ ARG A 35 5364 5273 5235 200 205 -374 C ATOM 144 NH1 ARG A 35 -50.943 26.936 158.800 1.00 29.08 N ANISOU 144 NH1 ARG A 35 3721 3675 3652 189 195 -385 N ATOM 145 NH2 ARG A 35 -50.355 27.971 160.756 1.00 48.66 N ANISOU 145 NH2 ARG A 35 6256 6125 6106 201 233 -364 N ATOM 146 N ALA A 36 -46.481 28.167 152.586 1.00 9.87 N ANISOU 146 N ALA A 36 1340 1316 1092 175 81 -429 N ATOM 147 CA ALA A 36 -46.482 28.115 151.125 1.00 12.45 C ANISOU 147 CA ALA A 36 1664 1663 1404 175 60 -440 C ATOM 148 C ALA A 36 -45.714 26.906 150.623 1.00 13.97 C ANISOU 148 C ALA A 36 1850 1861 1597 160 54 -462 C ATOM 149 O ALA A 36 -46.123 26.260 149.652 1.00 13.55 O ANISOU 149 O ALA A 36 1783 1820 1545 158 36 -477 O ATOM 150 CB ALA A 36 -45.886 29.391 150.527 1.00 13.06 C ANISOU 150 CB ALA A 36 1769 1746 1446 179 59 -429 C ATOM 151 N CYS A 37 -44.586 26.592 151.259 1.00 11.38 N ANISOU 151 N CYS A 37 1532 1523 1268 151 68 -464 N ATOM 152 CA CYS A 37 -43.821 25.437 150.817 1.00 11.22 C ANISOU 152 CA CYS A 37 1505 1507 1250 141 64 -485 C ATOM 153 C CYS A 37 -44.549 24.140 151.158 1.00 8.26 C ANISOU 153 C CYS A 37 1109 1124 907 137 59 -497 C ATOM 154 O CYS A 37 -44.524 23.189 150.374 1.00 14.06 O ANISOU 154 O CYS A 37 1833 1864 1644 132 46 -517 O ATOM 155 CB CYS A 37 -42.422 25.467 151.432 1.00 22.81 C ANISOU 155 CB CYS A 37 2988 2968 2713 135 78 -485 C ATOM 156 SG CYS A 37 -41.171 24.760 150.324 1.00 29.45 S ANISOU 156 SG CYS A 37 3827 3823 3539 127 75 -510 S ATOM 157 N PHE A 38 -45.214 24.092 152.314 1.00 10.48 N ANISOU 157 N PHE A 38 1384 1389 1209 138 69 -484 N ATOM 158 CA PHE A 38 -46.035 22.930 152.652 1.00 8.40 C ANISOU 158 CA PHE A 38 1100 1116 977 132 67 -492 C ATOM 159 C PHE A 38 -47.127 22.709 151.613 1.00 13.80 C ANISOU 159 C PHE A 38 1762 1814 1669 132 47 -502 C ATOM 160 O PHE A 38 -47.392 21.571 151.202 1.00 12.96 O ANISOU 160 O PHE A 38 1640 1705 1578 123 35 -520 O ATOM 161 CB PHE A 38 -46.640 23.135 154.034 1.00 9.31 C ANISOU 161 CB PHE A 38 1215 1213 1110 134 87 -474 C ATOM 162 CG PHE A 38 -47.278 21.908 154.616 1.00 9.43 C ANISOU 162 CG PHE A 38 1214 1213 1156 123 91 -479 C ATOM 163 CD1 PHE A 38 -48.618 21.620 154.383 1.00 13.24 C ANISOU 163 CD1 PHE A 38 1668 1699 1663 120 86 -481 C ATOM 164 CD2 PHE A 38 -46.536 21.040 155.387 1.00 8.40 C ANISOU 164 CD2 PHE A 38 1096 1063 1032 115 99 -482 C ATOM 165 CE1 PHE A 38 -49.209 20.492 154.909 1.00 13.63 C ANISOU 165 CE1 PHE A 38 1702 1733 1742 107 93 -485 C ATOM 166 CE2 PHE A 38 -47.125 19.905 155.919 1.00 11.06 C ANISOU 166 CE2 PHE A 38 1423 1383 1397 104 104 -485 C ATOM 167 CZ PHE A 38 -48.464 19.636 155.681 1.00 10.28 C ANISOU 167 CZ PHE A 38 1296 1288 1323 98 102 -487 C ATOM 168 N GLU A 39 -47.758 23.794 151.161 1.00 13.97 N ANISOU 168 N GLU A 39 1782 1847 1679 144 40 -492 N ATOM 169 CA GLU A 39 -48.828 23.678 150.182 1.00 8.90 C ANISOU 169 CA GLU A 39 1118 1219 1044 146 16 -500 C ATOM 170 C GLU A 39 -48.316 23.043 148.900 1.00 9.30 C ANISOU 170 C GLU A 39 1175 1282 1077 140 -5 -523 C ATOM 171 O GLU A 39 -49.017 22.232 148.282 1.00 15.12 O ANISOU 171 O GLU A 39 1893 2024 1829 134 -26 -539 O ATOM 172 CB GLU A 39 -49.432 25.064 149.934 1.00 8.98 C ANISOU 172 CB GLU A 39 1132 1239 1040 164 11 -483 C ATOM 173 CG GLU A 39 -50.800 25.043 149.269 1.00 9.28 C ANISOU 173 CG GLU A 39 1142 1289 1096 170 -13 -488 C ATOM 174 CD GLU A 39 -50.713 24.945 147.783 1.00 20.39 C ANISOU 174 CD GLU A 39 2555 2713 2479 171 -44 -503 C ATOM 175 OE1 GLU A 39 -51.773 24.750 147.163 1.00 22.26 O ANISOU 175 OE1 GLU A 39 2769 2959 2730 175 -71 -510 O ATOM 176 OE2 GLU A 39 -49.592 25.105 147.269 1.00 13.83 O ANISOU 176 OE2 GLU A 39 1754 1887 1615 169 -42 -507 O ATOM 177 N ARG A 40 -47.087 23.395 148.487 1.00 8.86 N ANISOU 177 N ARG A 40 1145 1233 990 141 1 -525 N ATOM 178 CA ARG A 40 -46.503 22.800 147.283 1.00 17.54 C ANISOU 178 CA ARG A 40 2252 2343 2069 136 -14 -548 C ATOM 179 C ARG A 40 -46.143 21.339 147.507 1.00 17.42 C ANISOU 179 C ARG A 40 2228 2317 2075 125 -13 -568 C ATOM 180 O ARG A 40 -46.315 20.507 146.610 1.00 16.52 O ANISOU 180 O ARG A 40 2109 2208 1960 120 -31 -591 O ATOM 181 CB ARG A 40 -45.255 23.578 146.842 1.00 23.14 C ANISOU 181 CB ARG A 40 2989 3062 2742 139 -2 -544 C ATOM 182 CG ARG A 40 -45.459 25.068 146.571 1.00 33.45 C ANISOU 182 CG ARG A 40 4311 4377 4023 149 -2 -522 C ATOM 183 CD ARG A 40 -44.124 25.828 146.306 1.00 45.51 C ANISOU 183 CD ARG A 40 5865 5909 5517 146 15 -517 C ATOM 184 NE ARG A 40 -44.322 27.277 146.128 1.00 56.88 N ANISOU 184 NE ARG A 40 7325 7352 6934 155 16 -494 N ATOM 185 CZ ARG A 40 -43.980 28.215 147.019 1.00 61.08 C ANISOU 185 CZ ARG A 40 7869 7874 7467 156 33 -474 C ATOM 186 NH1 ARG A 40 -43.402 27.867 148.165 1.00 62.76 N ANISOU 186 NH1 ARG A 40 8075 8072 7698 150 50 -473 N ATOM 187 NH2 ARG A 40 -44.204 29.509 146.766 1.00 55.19 N ANISOU 187 NH2 ARG A 40 7143 7128 6699 164 31 -455 N ATOM 188 N ASN A 41 -45.638 21.002 148.692 1.00 13.00 N ANISOU 188 N ASN A 41 1668 1739 1533 121 7 -561 N ATOM 189 CA ASN A 41 -45.231 19.623 148.939 1.00 15.91 C ANISOU 189 CA ASN A 41 2033 2093 1920 112 7 -580 C ATOM 190 C ASN A 41 -45.061 19.388 150.429 1.00 14.26 C ANISOU 190 C ASN A 41 1824 1860 1733 109 27 -566 C ATOM 191 O ASN A 41 -44.113 19.903 151.037 1.00 10.92 O ANISOU 191 O ASN A 41 1416 1434 1298 113 41 -555 O ATOM 192 CB ASN A 41 -43.927 19.302 148.227 1.00 18.29 C ANISOU 192 CB ASN A 41 2349 2401 2200 113 9 -598 C ATOM 193 CG ASN A 41 -43.592 17.823 148.272 1.00 23.77 C ANISOU 193 CG ASN A 41 3038 3080 2913 107 4 -621 C ATOM 194 OD1 ASN A 41 -44.378 17.012 148.744 1.00 25.34 O ANISOU 194 OD1 ASN A 41 3225 3262 3140 99 -2 -623 O ATOM 195 ND2 ASN A 41 -42.425 17.469 147.768 1.00 25.01 N ANISOU 195 ND2 ASN A 41 3206 3241 3055 110 9 -638 N ATOM 196 N PRO A 42 -45.953 18.626 151.058 1.00 15.69 N ANISOU 196 N PRO A 42 1990 2026 1945 101 27 -564 N ATOM 197 CA PRO A 42 -45.842 18.407 152.505 1.00 16.86 C ANISOU 197 CA PRO A 42 2144 2150 2110 98 46 -549 C ATOM 198 C PRO A 42 -44.748 17.432 152.912 1.00 11.91 C ANISOU 198 C PRO A 42 1531 1506 1488 95 49 -560 C ATOM 199 O PRO A 42 -44.544 17.247 154.118 1.00 12.74 O ANISOU 199 O PRO A 42 1647 1591 1603 94 63 -547 O ATOM 200 CB PRO A 42 -47.236 17.876 152.884 1.00 21.31 C ANISOU 200 CB PRO A 42 2686 2704 2706 88 47 -545 C ATOM 201 CG PRO A 42 -47.862 17.476 151.653 1.00 20.69 C ANISOU 201 CG PRO A 42 2590 2639 2631 83 22 -564 C ATOM 202 CD PRO A 42 -47.247 18.196 150.518 1.00 16.04 C ANISOU 202 CD PRO A 42 2012 2074 2009 94 10 -572 C ATOM 203 N TYR A 43 -44.060 16.825 151.939 1.00 8.79 N ANISOU 203 N TYR A 43 1138 1118 1084 96 36 -583 N ATOM 204 CA TYR A 43 -42.960 15.876 152.142 1.00 8.78 C ANISOU 204 CA TYR A 43 1147 1103 1088 98 36 -598 C ATOM 205 C TYR A 43 -41.691 16.387 151.484 1.00 14.17 C ANISOU 205 C TYR A 43 1838 1803 1744 107 37 -607 C ATOM 206 O TYR A 43 -41.163 15.738 150.562 1.00 12.67 O ANISOU 206 O TYR A 43 1646 1619 1548 110 29 -631 O ATOM 207 CB TYR A 43 -43.328 14.499 151.575 1.00 9.02 C ANISOU 207 CB TYR A 43 1170 1120 1135 90 21 -622 C ATOM 208 CG TYR A 43 -44.563 13.923 152.228 1.00 11.11 C ANISOU 208 CG TYR A 43 1425 1366 1430 76 21 -613 C ATOM 209 CD1 TYR A 43 -45.825 14.075 151.654 1.00 11.94 C ANISOU 209 CD1 TYR A 43 1511 1482 1544 67 11 -614 C ATOM 210 CD2 TYR A 43 -44.477 13.266 153.448 1.00 9.13 C ANISOU 210 CD2 TYR A 43 1185 1086 1199 71 32 -602 C ATOM 211 CE1 TYR A 43 -46.966 13.569 152.287 1.00 11.84 C ANISOU 211 CE1 TYR A 43 1484 1453 1562 52 15 -606 C ATOM 212 CE2 TYR A 43 -45.591 12.751 154.066 1.00 9.28 C ANISOU 212 CE2 TYR A 43 1196 1087 1245 56 38 -593 C ATOM 213 CZ TYR A 43 -46.831 12.907 153.490 1.00 17.78 C ANISOU 213 CZ TYR A 43 2247 2176 2332 46 31 -595 C ATOM 214 OH TYR A 43 -47.922 12.404 154.147 1.00 15.74 O ANISOU 214 OH TYR A 43 1977 1900 2104 29 39 -585 O ATOM 215 N PRO A 44 -41.134 17.522 151.921 1.00 12.11 N ANISOU 215 N PRO A 44 1585 1551 1467 113 49 -589 N ATOM 216 CA PRO A 44 -39.886 18.010 151.328 1.00 10.69 C ANISOU 216 CA PRO A 44 1410 1387 1265 118 53 -597 C ATOM 217 C PRO A 44 -38.695 17.123 151.671 1.00 14.70 C ANISOU 217 C PRO A 44 1919 1881 1784 121 53 -599 C ATOM 218 O PRO A 44 -38.619 16.537 152.755 1.00 13.47 O ANISOU 218 O PRO A 44 1768 1703 1648 123 52 -596 O ATOM 219 CB PRO A 44 -39.715 19.406 151.928 1.00 9.98 C ANISOU 219 CB PRO A 44 1328 1303 1161 120 64 -573 C ATOM 220 CG PRO A 44 -40.410 19.301 153.311 1.00 11.51 C ANISOU 220 CG PRO A 44 1526 1474 1375 118 68 -554 C ATOM 221 CD PRO A 44 -41.617 18.408 153.017 1.00 9.46 C ANISOU 221 CD PRO A 44 1254 1207 1133 113 60 -562 C ATOM 222 N GLY A 45 -37.759 17.034 150.720 1.00 12.66 N ANISOU 222 N GLY A 45 1658 1638 1515 123 53 -605 N ATOM 223 CA GLY A 45 -36.490 16.375 150.938 1.00 11.50 C ANISOU 223 CA GLY A 45 1509 1483 1378 129 54 -610 C ATOM 224 C GLY A 45 -35.486 17.337 151.545 1.00 13.55 C ANISOU 224 C GLY A 45 1768 1748 1630 131 64 -597 C ATOM 225 O GLY A 45 -35.799 18.485 151.844 1.00 12.36 O ANISOU 225 O GLY A 45 1624 1604 1467 127 70 -584 O ATOM 226 N ILE A 46 -34.253 16.852 151.736 1.00 10.36 N ANISOU 226 N ILE A 46 1358 1340 1236 138 64 -604 N ATOM 227 CA ILE A 46 -33.276 17.649 152.480 1.00 14.05 C ANISOU 227 CA ILE A 46 1824 1810 1704 139 68 -597 C ATOM 228 C ILE A 46 -32.939 18.933 151.730 1.00 10.92 C ANISOU 228 C ILE A 46 1425 1440 1284 131 82 -593 C ATOM 229 O ILE A 46 -32.760 19.995 152.340 1.00 11.01 O ANISOU 229 O ILE A 46 1443 1454 1288 127 87 -581 O ATOM 230 CB ILE A 46 -32.014 16.822 152.807 1.00 9.65 C ANISOU 230 CB ILE A 46 1255 1246 1166 150 63 -611 C ATOM 231 CG1 ILE A 46 -31.002 17.667 153.586 1.00 15.54 C ANISOU 231 CG1 ILE A 46 1997 1995 1914 151 64 -608 C ATOM 232 CG2 ILE A 46 -31.357 16.281 151.552 1.00 16.28 C ANISOU 232 CG2 ILE A 46 2081 2102 2004 154 69 -629 C ATOM 233 CD1 ILE A 46 -31.536 18.240 154.904 1.00 19.08 C ANISOU 233 CD1 ILE A 46 2464 2425 2361 148 57 -591 C ATOM 234 N ALA A 47 -32.874 18.875 150.401 1.00 13.46 N ANISOU 234 N ALA A 47 1742 1780 1591 129 90 -602 N ATOM 235 CA ALA A 47 -32.508 20.073 149.644 1.00 14.18 C ANISOU 235 CA ALA A 47 1834 1895 1658 121 105 -598 C ATOM 236 C ALA A 47 -33.562 21.165 149.780 1.00 12.02 C ANISOU 236 C ALA A 47 1578 1624 1367 115 105 -581 C ATOM 237 O ALA A 47 -33.231 22.339 149.962 1.00 16.97 O ANISOU 237 O ALA A 47 2210 2258 1980 108 114 -571 O ATOM 238 CB ALA A 47 -32.303 19.717 148.175 1.00 20.04 C ANISOU 238 CB ALA A 47 2574 2655 2385 122 113 -611 C ATOM 239 N THR A 48 -34.837 20.802 149.670 1.00 9.41 N ANISOU 239 N THR A 48 1253 1286 1036 117 94 -579 N ATOM 240 CA THR A 48 -35.907 21.775 149.875 1.00 11.00 C ANISOU 240 CA THR A 48 1467 1488 1225 114 93 -565 C ATOM 241 C THR A 48 -35.879 22.346 151.289 1.00 11.67 C ANISOU 241 C THR A 48 1558 1558 1319 115 95 -552 C ATOM 242 O THR A 48 -36.013 23.560 151.476 1.00 8.81 O ANISOU 242 O THR A 48 1207 1201 941 112 101 -540 O ATOM 243 CB THR A 48 -37.252 21.108 149.586 1.00 14.48 C ANISOU 243 CB THR A 48 1906 1925 1671 117 81 -572 C ATOM 244 OG1 THR A 48 -37.231 20.611 148.253 1.00 21.61 O ANISOU 244 OG1 THR A 48 2807 2841 2562 117 77 -586 O ATOM 245 CG2 THR A 48 -38.388 22.068 149.719 1.00 13.06 C ANISOU 245 CG2 THR A 48 1734 1749 1481 118 79 -563 C ATOM 246 N ARG A 49 -35.680 21.487 152.301 1.00 10.59 N ANISOU 246 N ARG A 49 1417 1401 1206 119 89 -554 N ATOM 247 CA ARG A 49 -35.639 21.973 153.678 1.00 9.46 C ANISOU 247 CA ARG A 49 1285 1242 1069 120 89 -542 C ATOM 248 C ARG A 49 -34.445 22.892 153.906 1.00 11.10 C ANISOU 248 C ARG A 49 1495 1456 1267 116 95 -539 C ATOM 249 O ARG A 49 -34.562 23.896 154.612 1.00 11.99 O ANISOU 249 O ARG A 49 1622 1562 1372 112 97 -521 O ATOM 250 CB ARG A 49 -35.595 20.807 154.667 1.00 7.89 C ANISOU 250 CB ARG A 49 1086 1018 893 125 80 -546 C ATOM 251 CG ARG A 49 -36.860 19.962 154.723 1.00 7.91 C ANISOU 251 CG ARG A 49 1089 1009 908 127 76 -549 C ATOM 252 CD ARG A 49 -36.861 19.057 155.964 1.00 7.92 C ANISOU 252 CD ARG A 49 1098 981 929 130 71 -547 C ATOM 253 NE ARG A 49 -35.678 18.197 156.063 1.00 8.01 N ANISOU 253 NE ARG A 49 1106 986 952 136 61 -558 N ATOM 254 CZ ARG A 49 -35.581 17.006 155.486 1.00 12.83 C ANISOU 254 CZ ARG A 49 1707 1592 1576 139 54 -572 C ATOM 255 NH1 ARG A 49 -36.591 16.530 154.748 1.00 9.17 N ANISOU 255 NH1 ARG A 49 1239 1132 1115 134 54 -580 N ATOM 256 NH2 ARG A 49 -34.476 16.291 155.634 1.00 8.45 N ANISOU 256 NH2 ARG A 49 1147 1030 1032 147 46 -581 N ATOM 257 N GLU A 50 -33.285 22.571 153.327 1.00 13.82 N ANISOU 257 N GLU A 50 1824 1812 1615 114 97 -552 N ATOM 258 CA GLU A 50 -32.125 23.444 153.526 1.00 11.93 C ANISOU 258 CA GLU A 50 1582 1581 1371 108 103 -554 C ATOM 259 C GLU A 50 -32.330 24.802 152.860 1.00 12.98 C ANISOU 259 C GLU A 50 1725 1728 1477 97 116 -540 C ATOM 260 O GLU A 50 -32.049 25.847 153.458 1.00 15.18 O ANISOU 260 O GLU A 50 2016 2002 1750 88 117 -524 O ATOM 261 CB GLU A 50 -30.861 22.778 152.987 1.00 12.38 C ANISOU 261 CB GLU A 50 1615 1649 1439 110 106 -574 C ATOM 262 CG GLU A 50 -30.332 21.667 153.846 1.00 13.88 C ANISOU 262 CG GLU A 50 1796 1821 1656 122 91 -584 C ATOM 263 CD GLU A 50 -29.702 22.173 155.138 1.00 26.71 C ANISOU 263 CD GLU A 50 3427 3432 3290 120 80 -576 C ATOM 264 OE1 GLU A 50 -29.300 21.317 155.954 1.00 30.61 O ANISOU 264 OE1 GLU A 50 3918 3909 3804 131 64 -581 O ATOM 265 OE2 GLU A 50 -29.596 23.411 155.336 1.00 26.57 O ANISOU 265 OE2 GLU A 50 3418 3418 3259 108 85 -559 O ATOM 266 N ARG A 51 -32.824 24.800 151.617 1.00 12.56 N ANISOU 266 N ARG A 51 1673 1693 1408 96 123 -546 N ATOM 267 CA ARG A 51 -33.107 26.056 150.919 1.00 11.97 C ANISOU 267 CA ARG A 51 1613 1630 1305 87 133 -532 C ATOM 268 C ARG A 51 -34.121 26.896 151.692 1.00 17.10 C ANISOU 268 C ARG A 51 2284 2264 1951 89 127 -508 C ATOM 269 O ARG A 51 -33.885 28.074 151.980 1.00 15.08 O ANISOU 269 O ARG A 51 2042 2004 1683 81 132 -492 O ATOM 270 CB ARG A 51 -33.609 25.757 149.505 1.00 18.30 C ANISOU 270 CB ARG A 51 2415 2448 2088 89 136 -542 C ATOM 271 CG ARG A 51 -33.805 27.005 148.643 1.00 34.78 C ANISOU 271 CG ARG A 51 4522 4550 4144 81 147 -530 C ATOM 272 CD ARG A 51 -34.232 26.671 147.213 1.00 41.33 C ANISOU 272 CD ARG A 51 5356 5396 4951 84 147 -540 C ATOM 273 NE ARG A 51 -35.569 26.075 147.132 1.00 46.14 N ANISOU 273 NE ARG A 51 5966 6000 5566 95 128 -541 N ATOM 274 CZ ARG A 51 -35.809 24.802 146.818 1.00 47.26 C ANISOU 274 CZ ARG A 51 6096 6139 5723 101 118 -554 C ATOM 275 NH1 ARG A 51 -34.803 23.973 146.549 1.00 46.29 N ANISOU 275 NH1 ARG A 51 5960 6018 5610 99 125 -567 N ATOM 276 NH2 ARG A 51 -37.059 24.355 146.760 1.00 44.64 N ANISOU 276 NH2 ARG A 51 5763 5802 5396 108 101 -558 N ATOM 277 N LEU A 52 -35.244 26.291 152.086 1.00 9.84 N ANISOU 277 N LEU A 52 1364 1333 1041 99 117 -506 N ATOM 278 CA LEU A 52 -36.223 27.038 152.866 1.00 8.64 C ANISOU 278 CA LEU A 52 1229 1167 887 103 115 -485 C ATOM 279 C LEU A 52 -35.621 27.551 154.177 1.00 10.99 C ANISOU 279 C LEU A 52 1538 1447 1191 100 115 -473 C ATOM 280 O LEU A 52 -35.870 28.697 154.578 1.00 13.03 O ANISOU 280 O LEU A 52 1816 1697 1438 98 119 -455 O ATOM 281 CB LEU A 52 -37.446 26.151 153.133 1.00 13.92 C ANISOU 281 CB LEU A 52 1891 1827 1571 113 107 -487 C ATOM 282 CG LEU A 52 -38.578 26.802 153.926 1.00 20.14 C ANISOU 282 CG LEU A 52 2691 2601 2360 119 108 -467 C ATOM 283 CD1 LEU A 52 -39.143 27.949 153.126 1.00 21.25 C ANISOU 283 CD1 LEU A 52 2842 2753 2479 121 110 -456 C ATOM 284 CD2 LEU A 52 -39.654 25.782 154.208 1.00 18.53 C ANISOU 284 CD2 LEU A 52 2475 2389 2177 125 104 -471 C ATOM 285 N ALA A 53 -34.837 26.710 154.867 1.00 10.55 N ANISOU 285 N ALA A 53 1473 1383 1154 100 110 -483 N ATOM 286 CA ALA A 53 -34.244 27.114 156.138 1.00 12.62 C ANISOU 286 CA ALA A 53 1747 1626 1421 98 105 -474 C ATOM 287 C ALA A 53 -33.413 28.383 155.972 1.00 18.55 C ANISOU 287 C ALA A 53 2507 2383 2158 85 110 -466 C ATOM 288 O ALA A 53 -33.566 29.350 156.727 1.00 11.20 O ANISOU 288 O ALA A 53 1598 1439 1219 82 110 -450 O ATOM 289 CB ALA A 53 -33.384 25.975 156.691 1.00 12.10 C ANISOU 289 CB ALA A 53 1668 1553 1376 101 95 -489 C ATOM 290 N GLN A 54 -32.551 28.399 154.958 1.00 12.07 N ANISOU 290 N GLN A 54 1669 1582 1334 76 117 -478 N ATOM 291 CA GLN A 54 -31.689 29.555 154.717 1.00 16.58 C ANISOU 291 CA GLN A 54 2246 2159 1893 59 125 -472 C ATOM 292 C GLN A 54 -32.483 30.769 154.269 1.00 17.28 C ANISOU 292 C GLN A 54 2360 2248 1958 56 133 -453 C ATOM 293 O GLN A 54 -32.188 31.895 154.677 1.00 19.40 O ANISOU 293 O GLN A 54 2646 2506 2217 46 134 -440 O ATOM 294 CB GLN A 54 -30.643 29.201 153.671 1.00 13.09 C ANISOU 294 CB GLN A 54 1779 1741 1454 51 135 -490 C ATOM 295 CG GLN A 54 -29.827 27.992 154.060 1.00 28.92 C ANISOU 295 CG GLN A 54 3757 3745 3485 57 126 -509 C ATOM 296 CD GLN A 54 -29.010 28.226 155.316 1.00 40.99 C ANISOU 296 CD GLN A 54 5287 5258 5030 53 112 -506 C ATOM 297 OE1 GLN A 54 -28.684 29.369 155.665 1.00 41.31 O ANISOU 297 OE1 GLN A 54 5341 5293 5063 39 112 -493 O ATOM 298 NE2 GLN A 54 -28.690 27.144 156.015 1.00 46.60 N ANISOU 298 NE2 GLN A 54 5985 5959 5763 65 96 -517 N ATOM 299 N ALA A 55 -33.506 30.559 153.446 1.00 11.25 N ANISOU 299 N ALA A 55 1597 1493 1183 65 135 -453 N ATOM 300 CA ALA A 55 -34.280 31.687 152.949 1.00 16.78 C ANISOU 300 CA ALA A 55 2321 2194 1861 66 140 -436 C ATOM 301 C ALA A 55 -34.963 32.443 154.075 1.00 25.31 C ANISOU 301 C ALA A 55 3424 3250 2941 73 135 -418 C ATOM 302 O ALA A 55 -35.113 33.666 153.991 1.00 27.72 O ANISOU 302 O ALA A 55 3753 3549 3229 69 139 -402 O ATOM 303 CB ALA A 55 -35.316 31.205 151.928 1.00 16.28 C ANISOU 303 CB ALA A 55 2253 2144 1789 77 138 -440 C ATOM 304 N ILE A 56 -35.378 31.751 155.139 1.00 18.41 N ANISOU 304 N ILE A 56 2547 2363 2085 83 128 -419 N ATOM 305 CA ILE A 56 -36.161 32.385 156.193 1.00 11.31 C ANISOU 305 CA ILE A 56 1672 1443 1184 93 127 -403 C ATOM 306 C ILE A 56 -35.381 32.558 157.486 1.00 12.72 C ANISOU 306 C ILE A 56 1863 1602 1369 87 122 -401 C ATOM 307 O ILE A 56 -35.927 33.123 158.446 1.00 17.40 O ANISOU 307 O ILE A 56 2479 2175 1957 94 123 -389 O ATOM 308 CB ILE A 56 -37.472 31.626 156.452 1.00 19.31 C ANISOU 308 CB ILE A 56 2677 2453 2209 110 127 -403 C ATOM 309 CG1 ILE A 56 -37.212 30.332 157.222 1.00 20.75 C ANISOU 309 CG1 ILE A 56 2845 2627 2411 111 122 -415 C ATOM 310 CG2 ILE A 56 -38.141 31.291 155.120 1.00 17.38 C ANISOU 310 CG2 ILE A 56 2416 2228 1960 114 126 -410 C ATOM 311 CD1 ILE A 56 -38.491 29.575 157.585 1.00 22.68 C ANISOU 311 CD1 ILE A 56 3083 2866 2669 124 124 -413 C ATOM 312 N GLY A 57 -34.125 32.123 157.536 1.00 17.84 N ANISOU 312 N GLY A 57 2496 2255 2026 75 117 -413 N ATOM 313 CA GLY A 57 -33.274 32.316 158.704 1.00 20.96 C ANISOU 313 CA GLY A 57 2902 2633 2428 68 107 -413 C ATOM 314 C GLY A 57 -33.594 31.433 159.890 1.00 20.55 C ANISOU 314 C GLY A 57 2855 2564 2387 81 98 -414 C ATOM 315 O GLY A 57 -33.603 31.909 161.029 1.00 22.63 O ANISOU 315 O GLY A 57 3146 2807 2646 82 92 -405 O ATOM 316 N ILE A 58 -33.868 30.159 159.658 1.00 18.09 N ANISOU 316 N ILE A 58 2523 2259 2090 89 97 -425 N ATOM 317 CA ILE A 58 -34.203 29.244 160.750 1.00 17.17 C ANISOU 317 CA ILE A 58 2414 2125 1984 100 90 -425 C ATOM 318 C ILE A 58 -33.351 28.005 160.537 1.00 10.63 C ANISOU 318 C ILE A 58 1560 1304 1175 100 79 -443 C ATOM 319 O ILE A 58 -33.193 27.574 159.385 1.00 16.30 O ANISOU 319 O ILE A 58 2253 2043 1898 98 84 -455 O ATOM 320 CB ILE A 58 -35.712 28.906 160.758 1.00 19.92 C ANISOU 320 CB ILE A 58 2765 2470 2332 112 102 -417 C ATOM 321 CG1 ILE A 58 -36.536 30.107 161.203 1.00 21.51 C ANISOU 321 CG1 ILE A 58 2994 2661 2517 117 113 -400 C ATOM 322 CG2 ILE A 58 -36.026 27.708 161.607 1.00 16.94 C ANISOU 322 CG2 ILE A 58 2390 2078 1968 120 99 -420 C ATOM 323 CD1 ILE A 58 -36.158 30.655 162.589 1.00 27.39 C ANISOU 323 CD1 ILE A 58 3772 3381 3253 117 108 -391 C ATOM 324 N PRO A 59 -32.787 27.381 161.576 1.00 13.66 N ANISOU 324 N PRO A 59 1951 1671 1568 104 64 -445 N ATOM 325 CA PRO A 59 -32.023 26.150 161.348 1.00 7.71 C ANISOU 325 CA PRO A 59 1173 923 835 108 52 -463 C ATOM 326 C PRO A 59 -32.872 25.043 160.729 1.00 9.02 C ANISOU 326 C PRO A 59 1324 1092 1009 116 60 -470 C ATOM 327 O PRO A 59 -34.060 24.880 161.039 1.00 10.09 O ANISOU 327 O PRO A 59 1473 1218 1141 121 69 -460 O ATOM 328 CB PRO A 59 -31.506 25.768 162.738 1.00 20.23 C ANISOU 328 CB PRO A 59 2777 2483 2425 114 32 -460 C ATOM 329 CG PRO A 59 -31.567 27.036 163.539 1.00 17.19 C ANISOU 329 CG PRO A 59 2423 2086 2021 108 31 -445 C ATOM 330 CD PRO A 59 -32.695 27.849 162.982 1.00 12.35 C ANISOU 330 CD PRO A 59 1818 1481 1394 106 54 -433 C ATOM 331 N GLU A 60 -32.243 24.295 159.834 1.00 7.83 N ANISOU 331 N GLU A 60 1146 958 873 117 58 -489 N ATOM 332 CA GLU A 60 -32.965 23.239 159.116 1.00 8.20 C ANISOU 332 CA GLU A 60 1179 1008 927 123 63 -500 C ATOM 333 C GLU A 60 -33.660 22.232 160.025 1.00 9.92 C ANISOU 333 C GLU A 60 1411 1201 1155 131 58 -495 C ATOM 334 O GLU A 60 -34.779 21.786 159.664 1.00 10.11 O ANISOU 334 O GLU A 60 1434 1226 1182 132 67 -494 O ATOM 335 CB GLU A 60 -32.006 22.520 158.150 1.00 7.95 C ANISOU 335 CB GLU A 60 1119 994 908 125 60 -523 C ATOM 336 CG GLU A 60 -32.706 21.476 157.275 1.00 9.81 C ANISOU 336 CG GLU A 60 1343 1235 1151 130 64 -537 C ATOM 337 CD GLU A 60 -32.832 20.090 157.938 1.00 14.66 C ANISOU 337 CD GLU A 60 1961 1826 1785 141 52 -544 C ATOM 338 OE1 GLU A 60 -32.104 19.821 158.918 1.00 17.96 O ANISOU 338 OE1 GLU A 60 2386 2226 2211 147 38 -542 O ATOM 339 OE2 GLU A 60 -33.649 19.255 157.462 1.00 13.87 O ANISOU 339 OE2 GLU A 60 1857 1722 1690 142 54 -551 O ATOM 340 N PRO A 61 -33.110 21.788 161.160 1.00 10.92 N ANISOU 340 N PRO A 61 1553 1307 1290 137 43 -492 N ATOM 341 CA PRO A 61 -33.860 20.840 161.999 1.00 12.05 C ANISOU 341 CA PRO A 61 1714 1424 1439 143 41 -485 C ATOM 342 C PRO A 61 -35.175 21.399 162.507 1.00 10.36 C ANISOU 342 C PRO A 61 1522 1203 1213 139 59 -465 C ATOM 343 O PRO A 61 -36.131 20.634 162.671 1.00 8.05 O ANISOU 343 O PRO A 61 1233 898 928 140 67 -462 O ATOM 344 CB PRO A 61 -32.899 20.535 163.157 1.00 7.94 C ANISOU 344 CB PRO A 61 1212 883 923 150 20 -483 C ATOM 345 CG PRO A 61 -31.516 20.738 162.527 1.00 9.33 C ANISOU 345 CG PRO A 61 1361 1078 1107 151 7 -500 C ATOM 346 CD PRO A 61 -31.707 21.941 161.638 1.00 9.30 C ANISOU 346 CD PRO A 61 1344 1099 1089 139 25 -498 C ATOM 347 N ARG A 62 -35.242 22.707 162.774 1.00 7.68 N ANISOU 347 N ARG A 62 1195 867 856 136 65 -453 N ATOM 348 CA ARG A 62 -36.492 23.304 163.223 1.00 8.87 C ANISOU 348 CA ARG A 62 1363 1011 995 135 84 -435 C ATOM 349 C ARG A 62 -37.532 23.279 162.113 1.00 7.96 C ANISOU 349 C ARG A 62 1224 914 885 133 98 -439 C ATOM 350 O ARG A 62 -38.731 23.115 162.378 1.00 7.61 O ANISOU 350 O ARG A 62 1184 863 845 134 112 -430 O ATOM 351 CB ARG A 62 -36.249 24.747 163.685 1.00 7.60 C ANISOU 351 CB ARG A 62 1223 850 814 133 86 -423 C ATOM 352 CG ARG A 62 -35.163 24.900 164.766 1.00 11.57 C ANISOU 352 CG ARG A 62 1750 1336 1311 134 68 -421 C ATOM 353 CD ARG A 62 -35.526 24.145 166.001 1.00 13.43 C ANISOU 353 CD ARG A 62 2013 1544 1545 141 67 -412 C ATOM 354 NE ARG A 62 -34.877 22.836 166.061 1.00 15.06 N ANISOU 354 NE ARG A 62 2211 1742 1769 145 49 -423 N ATOM 355 CZ ARG A 62 -35.434 21.730 166.560 1.00 20.37 C ANISOU 355 CZ ARG A 62 2895 2397 2449 149 53 -419 C ATOM 356 NH1 ARG A 62 -36.688 21.747 167.017 1.00 18.26 N ANISOU 356 NH1 ARG A 62 2645 2119 2176 147 77 -405 N ATOM 357 NH2 ARG A 62 -34.743 20.589 166.587 1.00 14.89 N ANISOU 357 NH2 ARG A 62 2194 1693 1769 154 34 -430 N ATOM 358 N VAL A 63 -37.086 23.479 160.868 1.00 7.56 N ANISOU 358 N VAL A 63 1151 887 835 130 94 -452 N ATOM 359 CA VAL A 63 -37.969 23.351 159.702 1.00 7.56 C ANISOU 359 CA VAL A 63 1129 905 838 128 101 -458 C ATOM 360 C VAL A 63 -38.493 21.933 159.586 1.00 7.64 C ANISOU 360 C VAL A 63 1127 907 868 128 98 -468 C ATOM 361 O VAL A 63 -39.675 21.709 159.302 1.00 7.67 O ANISOU 361 O VAL A 63 1123 913 880 127 106 -466 O ATOM 362 CB VAL A 63 -37.218 23.754 158.407 1.00 7.56 C ANISOU 362 CB VAL A 63 1112 930 830 125 96 -471 C ATOM 363 CG1 VAL A 63 -38.080 23.479 157.180 1.00 7.60 C ANISOU 363 CG1 VAL A 63 1098 952 836 124 99 -479 C ATOM 364 CG2 VAL A 63 -36.789 25.215 158.471 1.00 8.22 C ANISOU 364 CG2 VAL A 63 1209 1020 895 121 100 -459 C ATOM 365 N GLN A 64 -37.615 20.952 159.757 1.00 7.69 N ANISOU 365 N GLN A 64 1133 904 886 130 86 -480 N ATOM 366 CA GLN A 64 -38.045 19.568 159.630 1.00 7.79 C ANISOU 366 CA GLN A 64 1138 906 918 130 83 -491 C ATOM 367 C GLN A 64 -39.056 19.232 160.714 1.00 11.50 C ANISOU 367 C GLN A 64 1624 1352 1394 128 93 -474 C ATOM 368 O GLN A 64 -40.084 18.613 160.437 1.00 7.92 O ANISOU 368 O GLN A 64 1160 895 954 122 99 -476 O ATOM 369 CB GLN A 64 -36.834 18.636 159.706 1.00 8.18 C ANISOU 369 CB GLN A 64 1185 946 977 136 67 -506 C ATOM 370 CG GLN A 64 -37.196 17.147 159.651 1.00 9.56 C ANISOU 370 CG GLN A 64 1357 1104 1172 137 61 -517 C ATOM 371 CD GLN A 64 -35.989 16.252 159.369 1.00 11.80 C ANISOU 371 CD GLN A 64 1633 1383 1467 146 45 -538 C ATOM 372 OE1 GLN A 64 -34.885 16.496 159.862 1.00 10.78 O ANISOU 372 OE1 GLN A 64 1508 1251 1335 154 35 -538 O ATOM 373 NE2 GLN A 64 -36.201 15.205 158.581 1.00 8.76 N ANISOU 373 NE2 GLN A 64 1236 997 1095 146 41 -557 N ATOM 374 N ILE A 65 -38.803 19.691 161.950 1.00 7.83 N ANISOU 374 N ILE A 65 1186 869 918 131 96 -458 N ATOM 375 CA ILE A 65 -39.755 19.471 163.038 1.00 7.90 C ANISOU 375 CA ILE A 65 1216 857 930 129 111 -440 C ATOM 376 C ILE A 65 -41.105 20.124 162.721 1.00 7.89 C ANISOU 376 C ILE A 65 1203 868 929 125 131 -432 C ATOM 377 O ILE A 65 -42.170 19.561 163.013 1.00 8.01 O ANISOU 377 O ILE A 65 1215 873 958 119 146 -426 O ATOM 378 CB ILE A 65 -39.171 19.988 164.368 1.00 7.91 C ANISOU 378 CB ILE A 65 1252 839 914 134 110 -425 C ATOM 379 CG1 ILE A 65 -38.000 19.116 164.836 1.00 7.99 C ANISOU 379 CG1 ILE A 65 1275 832 928 139 88 -433 C ATOM 380 CG2 ILE A 65 -40.246 20.115 165.430 1.00 8.00 C ANISOU 380 CG2 ILE A 65 1287 832 920 132 133 -406 C ATOM 381 CD1 ILE A 65 -38.347 17.712 165.117 1.00 13.64 C ANISOU 381 CD1 ILE A 65 1997 1526 1661 137 87 -434 C ATOM 382 N TRP A 66 -41.086 21.311 162.121 1.00 7.79 N ANISOU 382 N TRP A 66 1181 876 902 128 133 -430 N ATOM 383 CA TRP A 66 -42.337 21.984 161.765 1.00 7.81 C ANISOU 383 CA TRP A 66 1171 890 906 128 148 -423 C ATOM 384 C TRP A 66 -43.119 21.212 160.693 1.00 8.34 C ANISOU 384 C TRP A 66 1206 970 993 122 144 -436 C ATOM 385 O TRP A 66 -44.344 21.047 160.814 1.00 9.55 O ANISOU 385 O TRP A 66 1348 1121 1161 119 157 -430 O ATOM 386 CB TRP A 66 -42.064 23.424 161.305 1.00 7.70 C ANISOU 386 CB TRP A 66 1160 894 873 134 147 -419 C ATOM 387 CG TRP A 66 -43.373 24.153 160.958 1.00 7.76 C ANISOU 387 CG TRP A 66 1154 912 882 139 160 -411 C ATOM 388 CD1 TRP A 66 -44.172 24.897 161.804 1.00 7.82 C ANISOU 388 CD1 TRP A 66 1175 910 885 146 179 -394 C ATOM 389 CD2 TRP A 66 -44.019 24.165 159.690 1.00 7.80 C ANISOU 389 CD2 TRP A 66 1131 939 895 138 153 -419 C ATOM 390 NE1 TRP A 66 -45.278 25.365 161.122 1.00 7.90 N ANISOU 390 NE1 TRP A 66 1163 935 902 151 185 -393 N ATOM 391 CE2 TRP A 66 -45.209 24.919 159.826 1.00 7.89 C ANISOU 391 CE2 TRP A 66 1137 953 909 146 166 -407 C ATOM 392 CE3 TRP A 66 -43.721 23.586 158.453 1.00 7.81 C ANISOU 392 CE3 TRP A 66 1112 956 899 134 136 -437 C ATOM 393 CZ2 TRP A 66 -46.095 25.121 158.755 1.00 7.99 C ANISOU 393 CZ2 TRP A 66 1122 984 928 150 159 -412 C ATOM 394 CZ3 TRP A 66 -44.595 23.785 157.397 1.00 7.90 C ANISOU 394 CZ3 TRP A 66 1101 986 915 135 130 -442 C ATOM 395 CH2 TRP A 66 -45.760 24.558 157.551 1.00 7.99 C ANISOU 395 CH2 TRP A 66 1106 1000 929 144 139 -429 C ATOM 396 N PHE A 67 -42.437 20.719 159.646 1.00 8.82 N ANISOU 396 N PHE A 67 1252 1043 1056 120 126 -455 N ATOM 397 CA PHE A 67 -43.140 19.939 158.628 1.00 8.11 C ANISOU 397 CA PHE A 67 1136 963 982 114 119 -470 C ATOM 398 C PHE A 67 -43.782 18.709 159.247 1.00 9.83 C ANISOU 398 C PHE A 67 1353 1159 1224 106 125 -469 C ATOM 399 O PHE A 67 -44.890 18.331 158.867 1.00 8.27 O ANISOU 399 O PHE A 67 1135 964 1044 98 127 -472 O ATOM 400 CB PHE A 67 -42.207 19.527 157.482 1.00 8.51 C ANISOU 400 CB PHE A 67 1177 1029 1029 115 101 -492 C ATOM 401 CG PHE A 67 -42.157 20.543 156.362 1.00 9.27 C ANISOU 401 CG PHE A 67 1264 1151 1105 118 97 -495 C ATOM 402 CD1 PHE A 67 -41.256 21.615 156.407 1.00 9.31 C ANISOU 402 CD1 PHE A 67 1283 1165 1090 123 99 -488 C ATOM 403 CD2 PHE A 67 -43.039 20.465 155.304 1.00 8.03 C ANISOU 403 CD2 PHE A 67 1088 1010 952 116 89 -504 C ATOM 404 CE1 PHE A 67 -41.237 22.591 155.395 1.00 8.99 C ANISOU 404 CE1 PHE A 67 1238 1147 1029 125 97 -488 C ATOM 405 CE2 PHE A 67 -43.028 21.434 154.275 1.00 10.39 C ANISOU 405 CE2 PHE A 67 1385 1333 1231 121 84 -504 C ATOM 406 CZ PHE A 67 -42.135 22.494 154.323 1.00 7.90 C ANISOU 406 CZ PHE A 67 1085 1024 892 125 89 -496 C ATOM 407 N GLN A 68 -43.106 18.090 160.218 1.00 8.14 N ANISOU 407 N GLN A 68 1161 920 1011 106 125 -465 N ATOM 408 CA GLN A 68 -43.694 16.939 160.896 1.00 8.31 C ANISOU 408 CA GLN A 68 1189 917 1053 96 133 -462 C ATOM 409 C GLN A 68 -44.917 17.343 161.694 1.00 8.41 C ANISOU 409 C GLN A 68 1202 922 1070 91 158 -442 C ATOM 410 O GLN A 68 -45.938 16.641 161.671 1.00 8.60 O ANISOU 410 O GLN A 68 1211 939 1117 79 168 -442 O ATOM 411 CB GLN A 68 -42.646 16.278 161.791 1.00 8.32 C ANISOU 411 CB GLN A 68 1219 893 1051 100 126 -460 C ATOM 412 CG GLN A 68 -41.520 15.621 161.003 1.00 8.31 C ANISOU 412 CG GLN A 68 1210 895 1051 106 102 -482 C ATOM 413 CD GLN A 68 -40.351 15.253 161.906 1.00 9.80 C ANISOU 413 CD GLN A 68 1426 1062 1234 115 92 -479 C ATOM 414 OE1 GLN A 68 -40.391 15.484 163.130 1.00 13.57 O ANISOU 414 OE1 GLN A 68 1932 1522 1703 116 100 -460 O ATOM 415 NE2 GLN A 68 -39.299 14.744 161.312 1.00 8.33 N ANISOU 415 NE2 GLN A 68 1233 880 1051 123 73 -499 N ATOM 416 N ASN A 69 -44.838 18.468 162.431 1.00 8.31 N ANISOU 416 N ASN A 69 1209 912 1039 100 172 -426 N ATOM 417 CA ASN A 69 -45.979 18.885 163.237 1.00 8.44 C ANISOU 417 CA ASN A 69 1227 921 1059 99 200 -408 C ATOM 418 C ASN A 69 -47.132 19.327 162.344 1.00 14.93 C ANISOU 418 C ASN A 69 2012 1766 1895 97 204 -411 C ATOM 419 O ASN A 69 -48.301 19.057 162.644 1.00 9.10 O ANISOU 419 O ASN A 69 1258 1023 1177 89 224 -405 O ATOM 420 CB ASN A 69 -45.586 20.012 164.200 1.00 8.34 C ANISOU 420 CB ASN A 69 1247 904 1020 111 211 -392 C ATOM 421 CG ASN A 69 -44.908 19.505 165.453 1.00 8.39 C ANISOU 421 CG ASN A 69 1293 881 1015 110 214 -382 C ATOM 422 OD1 ASN A 69 -45.389 18.566 166.101 1.00 9.06 O ANISOU 422 OD1 ASN A 69 1387 943 1111 101 228 -376 O ATOM 423 ND2 ASN A 69 -43.812 20.141 165.830 1.00 8.39 N ANISOU 423 ND2 ASN A 69 1318 878 991 120 201 -380 N ATOM 424 N GLU A 70 -46.816 19.982 161.226 1.00 8.38 N ANISOU 424 N GLU A 70 1167 961 1056 105 185 -422 N ATOM 425 CA GLU A 70 -47.869 20.501 160.359 1.00 8.47 C ANISOU 425 CA GLU A 70 1146 994 1078 107 184 -425 C ATOM 426 C GLU A 70 -48.618 19.371 159.651 1.00 8.66 C ANISOU 426 C GLU A 70 1139 1020 1132 92 174 -439 C ATOM 427 O GLU A 70 -49.843 19.458 159.466 1.00 8.86 O ANISOU 427 O GLU A 70 1136 1052 1177 89 182 -437 O ATOM 428 CB GLU A 70 -47.270 21.491 159.361 1.00 8.31 C ANISOU 428 CB GLU A 70 1124 996 1036 118 166 -431 C ATOM 429 CG GLU A 70 -48.319 22.178 158.516 1.00 8.42 C ANISOU 429 CG GLU A 70 1111 1031 1056 124 161 -432 C ATOM 430 CD GLU A 70 -49.153 23.204 159.293 1.00 8.49 C ANISOU 430 CD GLU A 70 1123 1038 1065 136 184 -413 C ATOM 431 OE1 GLU A 70 -48.813 23.544 160.439 1.00 14.02 O ANISOU 431 OE1 GLU A 70 1851 1722 1754 140 204 -400 O ATOM 432 OE2 GLU A 70 -50.138 23.705 158.730 1.00 15.38 O ANISOU 432 OE2 GLU A 70 1970 1926 1948 144 181 -412 O ATOM 433 N ARG A 71 -47.917 18.289 159.267 1.00 8.65 N ANISOU 433 N ARG A 71 1142 1011 1135 83 157 -455 N ATOM 434 CA ARG A 71 -48.627 17.133 158.721 1.00 8.87 C ANISOU 434 CA ARG A 71 1145 1035 1191 67 148 -469 C ATOM 435 C ARG A 71 -49.546 16.529 159.773 1.00 13.26 C ANISOU 435 C ARG A 71 1699 1569 1772 54 174 -455 C ATOM 436 O ARG A 71 -50.660 16.099 159.469 1.00 10.59 O ANISOU 436 O ARG A 71 1330 1232 1461 40 176 -459 O ATOM 437 CB ARG A 71 -47.648 16.072 158.214 1.00 8.84 C ANISOU 437 CB ARG A 71 1152 1022 1186 63 128 -488 C ATOM 438 CG ARG A 71 -46.880 16.454 156.945 1.00 8.72 C ANISOU 438 CG ARG A 71 1131 1030 1150 73 104 -506 C ATOM 439 CD ARG A 71 -46.256 15.238 156.320 1.00 8.79 C ANISOU 439 CD ARG A 71 1143 1031 1167 67 86 -529 C ATOM 440 NE ARG A 71 -45.284 14.588 157.203 1.00 10.99 N ANISOU 440 NE ARG A 71 1447 1284 1444 69 90 -526 N ATOM 441 CZ ARG A 71 -43.967 14.773 157.150 1.00 12.18 C ANISOU 441 CZ ARG A 71 1614 1438 1576 82 83 -532 C ATOM 442 NH1 ARG A 71 -43.424 15.595 156.250 1.00 13.94 N ANISOU 442 NH1 ARG A 71 1830 1687 1778 91 75 -540 N ATOM 443 NH2 ARG A 71 -43.179 14.134 158.011 1.00 12.78 N ANISOU 443 NH2 ARG A 71 1712 1489 1655 85 83 -529 N ATOM 444 N SER A 72 -49.093 16.489 161.020 1.00 9.68 N ANISOU 444 N SER A 72 1278 1093 1307 55 194 -439 N ATOM 445 CA SER A 72 -49.928 15.941 162.080 1.00 18.37 C ANISOU 445 CA SER A 72 2382 2171 2426 42 223 -425 C ATOM 446 C SER A 72 -51.167 16.804 162.285 1.00 18.85 C ANISOU 446 C SER A 72 2419 2246 2499 44 247 -413 C ATOM 447 O SER A 72 -52.268 16.280 162.500 1.00 15.32 O ANISOU 447 O SER A 72 1947 1792 2080 28 265 -409 O ATOM 448 CB SER A 72 -49.105 15.834 163.365 1.00 22.00 C ANISOU 448 CB SER A 72 2889 2604 2865 46 236 -409 C ATOM 449 OG SER A 72 -49.761 15.028 164.314 1.00 45.57 O ANISOU 449 OG SER A 72 5885 5563 5867 30 262 -397 O ATOM 450 N ARG A 73 -51.012 18.129 162.187 1.00 13.54 N ANISOU 450 N ARG A 73 1749 1592 1804 64 247 -407 N ATOM 451 CA ARG A 73 -52.164 19.019 162.281 1.00 13.41 C ANISOU 451 CA ARG A 73 1707 1589 1798 72 267 -398 C ATOM 452 C ARG A 73 -53.102 18.837 161.102 1.00 18.07 C ANISOU 452 C ARG A 73 2248 2202 2417 66 249 -412 C ATOM 453 O ARG A 73 -54.320 18.829 161.272 1.00 17.58 O ANISOU 453 O ARG A 73 2153 2143 2383 60 267 -408 O ATOM 454 CB ARG A 73 -51.719 20.474 162.356 1.00 11.55 C ANISOU 454 CB ARG A 73 1489 1366 1532 96 267 -390 C ATOM 455 CG ARG A 73 -51.222 20.867 163.728 1.00 14.84 C ANISOU 455 CG ARG A 73 1950 1762 1925 103 293 -373 C ATOM 456 CD ARG A 73 -50.842 22.347 163.762 1.00 10.69 C ANISOU 456 CD ARG A 73 1443 1248 1372 125 291 -367 C ATOM 457 NE ARG A 73 -49.622 22.647 163.000 1.00 13.62 N ANISOU 457 NE ARG A 73 1827 1628 1721 130 259 -377 N ATOM 458 CZ ARG A 73 -48.401 22.736 163.515 1.00 15.97 C ANISOU 458 CZ ARG A 73 2161 1913 1993 132 252 -375 C ATOM 459 NH1 ARG A 73 -48.202 22.513 164.802 1.00 13.36 N ANISOU 459 NH1 ARG A 73 1864 1560 1654 130 271 -363 N ATOM 460 NH2 ARG A 73 -47.365 23.035 162.734 1.00 12.01 N ANISOU 460 NH2 ARG A 73 1664 1423 1476 135 225 -385 N ATOM 461 N GLN A 74 -52.562 18.705 159.897 1.00 12.22 N ANISOU 461 N GLN A 74 1499 1474 1668 67 213 -430 N ATOM 462 CA GLN A 74 -53.436 18.627 158.734 1.00 14.66 C ANISOU 462 CA GLN A 74 1766 1805 2000 64 191 -444 C ATOM 463 C GLN A 74 -54.131 17.275 158.658 1.00 22.59 C ANISOU 463 C GLN A 74 2746 2797 3041 37 189 -454 C ATOM 464 O GLN A 74 -55.320 17.203 158.337 1.00 22.78 O ANISOU 464 O GLN A 74 2728 2830 3096 30 189 -458 O ATOM 465 CB GLN A 74 -52.634 18.896 157.461 1.00 21.71 C ANISOU 465 CB GLN A 74 2664 2715 2869 73 154 -460 C ATOM 466 CG GLN A 74 -51.983 20.265 157.429 1.00 19.24 C ANISOU 466 CG GLN A 74 2374 2415 2522 96 154 -451 C ATOM 467 CD GLN A 74 -52.888 21.336 156.863 1.00 40.16 C ANISOU 467 CD GLN A 74 4999 5086 5174 111 148 -447 C ATOM 468 OE1 GLN A 74 -53.167 22.343 157.518 1.00 51.51 O ANISOU 468 OE1 GLN A 74 6444 6524 6605 127 168 -431 O ATOM 469 NE2 GLN A 74 -53.341 21.132 155.628 1.00 41.86 N ANISOU 469 NE2 GLN A 74 5188 5318 5398 109 117 -462 N ATOM 470 N LEU A 75 -53.413 16.191 158.961 1.00 21.71 N ANISOU 470 N LEU A 75 2659 2662 2928 23 188 -459 N ATOM 471 CA LEU A 75 -54.025 14.863 158.919 1.00 27.65 C ANISOU 471 CA LEU A 75 3393 3397 3715 -4 187 -468 C ATOM 472 C LEU A 75 -55.120 14.716 159.968 1.00 35.00 C ANISOU 472 C LEU A 75 4308 4316 4675 -19 226 -451 C ATOM 473 O LEU A 75 -56.152 14.087 159.708 1.00 39.76 O ANISOU 473 O LEU A 75 4874 4918 5315 -40 226 -457 O ATOM 474 CB LEU A 75 -52.962 13.787 159.112 1.00 21.98 C ANISOU 474 CB LEU A 75 2710 2653 2987 -13 179 -475 C ATOM 475 CG LEU A 75 -52.067 13.515 157.905 1.00 29.73 C ANISOU 475 CG LEU A 75 3698 3645 3953 -6 140 -499 C ATOM 476 CD1 LEU A 75 -50.859 12.652 158.305 1.00 24.18 C ANISOU 476 CD1 LEU A 75 3034 2916 3238 -7 137 -503 C ATOM 477 CD2 LEU A 75 -52.882 12.828 156.819 1.00 28.74 C ANISOU 477 CD2 LEU A 75 3538 3528 3856 -23 115 -521 C ATOM 478 N ARG A 76 -54.919 15.283 161.159 1.00 28.34 N ANISOU 478 N ARG A 76 3492 3462 3814 -8 260 -429 N ATOM 479 CA ARG A 76 -55.945 15.170 162.190 1.00 38.63 C ANISOU 479 CA ARG A 76 4783 4753 5140 -21 303 -412 C ATOM 480 C ARG A 76 -57.187 15.975 161.826 1.00 47.02 C ANISOU 480 C ARG A 76 5796 5843 6228 -14 310 -412 C ATOM 481 O ARG A 76 -58.317 15.501 161.998 1.00 42.18 O ANISOU 481 O ARG A 76 5145 5228 5654 -34 329 -411 O ATOM 482 CB ARG A 76 -55.388 15.612 163.539 1.00 41.23 C ANISOU 482 CB ARG A 76 5161 5065 5440 -10 336 -390 C ATOM 483 CG ARG A 76 -56.451 15.733 164.614 1.00 49.00 C ANISOU 483 CG ARG A 76 6135 6040 6441 -18 386 -372 C ATOM 484 CD ARG A 76 -55.838 15.979 165.984 1.00 51.45 C ANISOU 484 CD ARG A 76 6503 6328 6718 -9 417 -351 C ATOM 485 NE ARG A 76 -55.313 17.333 166.100 1.00 59.24 N ANISOU 485 NE ARG A 76 7509 7329 7670 22 414 -347 N ATOM 486 CZ ARG A 76 -54.022 17.653 166.060 1.00 62.70 C ANISOU 486 CZ ARG A 76 7986 7764 8072 36 389 -349 C ATOM 487 NH1 ARG A 76 -53.657 18.927 166.173 1.00 63.27 N ANISOU 487 NH1 ARG A 76 8074 7848 8117 61 389 -345 N ATOM 488 NH2 ARG A 76 -53.094 16.708 165.920 1.00 57.87 N ANISOU 488 NH2 ARG A 76 7398 7136 7454 26 365 -356 N ATOM 489 N GLN A 77 -56.999 17.190 161.308 1.00 50.24 N ANISOU 489 N GLN A 77 6200 6275 6614 14 295 -413 N ATOM 490 CA GLN A 77 -58.143 17.987 160.879 1.00 54.35 C ANISOU 490 CA GLN A 77 6673 6821 7158 25 296 -414 C ATOM 491 C GLN A 77 -58.844 17.351 159.684 1.00 55.92 C ANISOU 491 C GLN A 77 6823 7034 7391 9 261 -435 C ATOM 492 O GLN A 77 -60.078 17.281 159.656 1.00 59.78 O ANISOU 492 O GLN A 77 7262 7531 7920 0 271 -435 O ATOM 493 CB GLN A 77 -57.698 19.418 160.582 1.00 58.71 C ANISOU 493 CB GLN A 77 7240 7391 7677 59 284 -410 C ATOM 494 CG GLN A 77 -57.203 20.126 161.848 1.00 70.20 C ANISOU 494 CG GLN A 77 8739 8832 9102 74 321 -390 C ATOM 495 CD GLN A 77 -56.777 21.566 161.618 1.00 78.07 C ANISOU 495 CD GLN A 77 9754 9843 10067 105 311 -386 C ATOM 496 OE1 GLN A 77 -55.583 21.868 161.510 1.00 80.52 O ANISOU 496 OE1 GLN A 77 10103 10148 10341 113 295 -386 O ATOM 497 NE2 GLN A 77 -57.755 22.469 161.556 1.00 77.99 N ANISOU 497 NE2 GLN A 77 9713 9848 10071 124 322 -382 N ATOM 498 N HIS A 78 -58.081 16.853 158.703 1.00 56.55 N ANISOU 498 N HIS A 78 6915 7115 7456 5 219 -452 N ATOM 499 CA HIS A 78 -58.695 16.107 157.605 1.00 58.39 C ANISOU 499 CA HIS A 78 7109 7357 7719 -13 184 -474 C ATOM 500 C HIS A 78 -59.420 14.861 158.112 1.00 58.72 C ANISOU 500 C HIS A 78 7130 7378 7804 -48 203 -475 C ATOM 501 O HIS A 78 -60.405 14.425 157.505 1.00 53.49 O ANISOU 501 O HIS A 78 6420 6724 7180 -65 186 -488 O ATOM 502 CB HIS A 78 -57.636 15.709 156.566 1.00 59.67 C ANISOU 502 CB HIS A 78 7298 7521 7854 -11 143 -493 C ATOM 503 CG HIS A 78 -57.504 16.654 155.400 1.00 62.08 C ANISOU 503 CG HIS A 78 7597 7855 8136 13 107 -503 C ATOM 504 ND1 HIS A 78 -58.195 16.482 154.217 1.00 65.29 N ANISOU 504 ND1 HIS A 78 7967 8279 8560 8 68 -521 N ATOM 505 CD2 HIS A 78 -56.715 17.743 155.216 1.00 53.86 C ANISOU 505 CD2 HIS A 78 6584 6826 7055 39 103 -496 C ATOM 506 CE1 HIS A 78 -57.858 17.437 153.369 1.00 59.45 C ANISOU 506 CE1 HIS A 78 7238 7561 7790 33 43 -524 C ATOM 507 NE2 HIS A 78 -56.960 18.214 153.949 1.00 51.36 N ANISOU 507 NE2 HIS A 78 6251 6534 6731 51 65 -509 N ATOM 508 N ARG A 79 -58.952 14.279 159.223 1.00 58.57 N ANISOU 508 N ARG A 79 7146 7329 7778 -61 237 -461 N ATOM 509 CA ARG A 79 -59.515 13.035 159.736 1.00 58.25 C ANISOU 509 CA ARG A 79 7096 7264 7774 -97 256 -460 C ATOM 510 C ARG A 79 -60.911 13.226 160.317 1.00 69.12 C ANISOU 510 C ARG A 79 8425 8647 9192 -108 293 -449 C ATOM 511 O ARG A 79 -61.659 12.248 160.429 1.00 76.82 O ANISOU 511 O ARG A 79 9372 9607 10207 -142 302 -452 O ATOM 512 CB ARG A 79 -58.571 12.442 160.788 1.00 52.56 C ANISOU 512 CB ARG A 79 6433 6509 7029 -103 281 -446 C ATOM 513 CG ARG A 79 -58.889 11.035 161.254 1.00 53.33 C ANISOU 513 CG ARG A 79 6534 6574 7156 -140 296 -445 C ATOM 514 CD ARG A 79 -57.642 10.142 161.278 1.00 55.52 C ANISOU 514 CD ARG A 79 6864 6823 7409 -143 277 -451 C ATOM 515 NE ARG A 79 -56.388 10.879 161.456 1.00 63.62 N ANISOU 515 NE ARG A 79 7934 7854 8386 -111 270 -446 N ATOM 516 CZ ARG A 79 -55.840 11.182 162.635 1.00 65.20 C ANISOU 516 CZ ARG A 79 8177 8038 8560 -100 300 -424 C ATOM 517 NH1 ARG A 79 -56.432 10.822 163.768 1.00 71.24 N ANISOU 517 NH1 ARG A 79 8951 8780 9338 -117 343 -404 N ATOM 518 NH2 ARG A 79 -54.698 11.854 162.685 1.00 53.53 N ANISOU 518 NH2 ARG A 79 6733 6565 7041 -72 287 -423 N ATOM 519 N ARG A 80 -61.289 14.459 160.674 1.00 72.03 N ANISOU 519 N ARG A 80 8780 9034 9552 -82 314 -436 N ATOM 520 CA ARG A 80 -62.615 14.717 161.221 1.00 75.84 C ANISOU 520 CA ARG A 80 9215 9525 10076 -89 352 -426 C ATOM 521 C ARG A 80 -63.409 15.769 160.456 1.00 75.56 C ANISOU 521 C ARG A 80 9128 9525 10056 -64 332 -434 C ATOM 522 O ARG A 80 -64.546 16.061 160.843 1.00 72.99 O ANISOU 522 O ARG A 80 8756 9210 9768 -66 361 -428 O ATOM 523 CB ARG A 80 -62.510 15.116 162.699 1.00 79.38 C ANISOU 523 CB ARG A 80 9698 9958 10506 -81 412 -401 C ATOM 524 CG ARG A 80 -62.109 13.946 163.589 1.00 82.82 C ANISOU 524 CG ARG A 80 10173 10356 10938 -111 439 -391 C ATOM 525 CD ARG A 80 -61.726 14.406 164.975 1.00 84.97 C ANISOU 525 CD ARG A 80 10496 10612 11177 -99 488 -366 C ATOM 526 NE ARG A 80 -61.117 15.732 164.944 1.00 88.25 N ANISOU 526 NE ARG A 80 10934 11044 11552 -58 479 -363 N ATOM 527 CZ ARG A 80 -60.145 16.126 165.762 1.00 88.82 C ANISOU 527 CZ ARG A 80 11068 11100 11577 -41 493 -350 C ATOM 528 NH1 ARG A 80 -59.660 15.282 166.667 1.00 91.25 N ANISOU 528 NH1 ARG A 80 11423 11377 11872 -60 514 -338 N ATOM 529 NH2 ARG A 80 -59.652 17.357 165.670 1.00 82.94 N ANISOU 529 NH2 ARG A 80 10341 10371 10800 -7 483 -348 N ATOM 530 N GLU A 81 -62.847 16.348 159.394 1.00 77.30 N ANISOU 530 N GLU A 81 9356 9763 10249 -41 283 -447 N ATOM 531 CA GLU A 81 -63.631 17.085 158.408 1.00 77.88 C ANISOU 531 CA GLU A 81 9380 9868 10341 -22 250 -458 C ATOM 532 C GLU A 81 -64.051 16.173 157.255 1.00 80.36 C ANISOU 532 C GLU A 81 9659 10189 10686 -47 202 -482 C ATOM 533 O GLU A 81 -65.229 16.136 156.889 1.00 82.91 O ANISOU 533 O GLU A 81 9920 10527 11055 -55 192 -490 O ATOM 534 CB GLU A 81 -62.843 18.293 157.877 1.00 75.82 C ANISOU 534 CB GLU A 81 9152 9623 10033 17 225 -456 C ATOM 535 CG GLU A 81 -62.779 19.502 158.821 1.00 72.25 C ANISOU 535 CG GLU A 81 8720 9172 9559 47 265 -435 C ATOM 536 CD GLU A 81 -62.106 20.720 158.184 1.00 70.75 C ANISOU 536 CD GLU A 81 8558 8997 9326 83 236 -435 C ATOM 537 OE1 GLU A 81 -61.911 20.725 156.948 1.00 71.08 O ANISOU 537 OE1 GLU A 81 8594 9053 9360 87 187 -450 O ATOM 538 OE2 GLU A 81 -61.772 21.676 158.918 1.00 67.41 O ANISOU 538 OE2 GLU A 81 8165 8570 8877 107 264 -419 O ATOM 539 N SER A 82 -63.107 15.427 156.683 1.00 83.61 N ANISOU 539 N SER A 82 10107 10588 11073 -59 171 -495 N ATOM 540 CA SER A 82 -63.430 14.426 155.664 1.00 81.36 C ANISOU 540 CA SER A 82 9797 10303 10814 -85 127 -520 C ATOM 541 C SER A 82 -63.961 13.153 156.325 1.00 78.33 C ANISOU 541 C SER A 82 9396 9893 10473 -128 154 -519 C ATOM 542 O SER A 82 -64.773 13.208 157.254 1.00 73.45 O ANISOU 542 O SER A 82 8749 9271 9886 -138 199 -504 O ATOM 543 CB SER A 82 -62.205 14.095 154.793 1.00 79.55 C ANISOU 543 CB SER A 82 9615 10070 10541 -80 87 -536 C ATOM 544 OG SER A 82 -61.760 15.215 154.042 1.00 76.69 O ANISOU 544 OG SER A 82 9266 9731 10141 -45 60 -537 O ATOM 545 N PRO A 92 -41.125 11.446 145.353 1.00 51.11 N ANISOU 545 N PRO A 92 6525 6493 6401 103 -33 -728 N ATOM 546 CA PRO A 92 -40.384 11.511 146.626 1.00 49.04 C ANISOU 546 CA PRO A 92 6262 6217 6155 108 -17 -711 C ATOM 547 C PRO A 92 -39.046 12.245 146.504 1.00 40.21 C ANISOU 547 C PRO A 92 5146 5115 5017 118 1 -697 C ATOM 548 O PRO A 92 -38.148 11.750 145.814 1.00 39.48 O ANISOU 548 O PRO A 92 5058 5026 4917 125 6 -707 O ATOM 549 CB PRO A 92 -40.156 10.035 146.980 1.00 46.38 C ANISOU 549 CB PRO A 92 5929 5849 5843 108 -24 -723 C ATOM 550 CG PRO A 92 -40.196 9.320 145.657 1.00 45.61 C ANISOU 550 CG PRO A 92 5839 5757 5735 108 -36 -744 C ATOM 551 CD PRO A 92 -41.202 10.074 144.822 1.00 48.00 C ANISOU 551 CD PRO A 92 6138 6082 6018 100 -47 -749 C ATOM 552 N GLU A 93 -38.917 13.400 147.157 1.00 31.79 N ANISOU 552 N GLU A 93 4076 4059 3944 119 13 -678 N ATOM 553 CA GLU A 93 -37.654 14.128 147.134 1.00 23.27 C ANISOU 553 CA GLU A 93 2998 2993 2850 125 30 -666 C ATOM 554 C GLU A 93 -36.601 13.393 147.970 1.00 26.48 C ANISOU 554 C GLU A 93 3402 3381 3278 133 34 -666 C ATOM 555 O GLU A 93 -36.916 12.565 148.829 1.00 29.74 O ANISOU 555 O GLU A 93 3816 3769 3715 133 26 -667 O ATOM 556 CB GLU A 93 -37.861 15.565 147.622 1.00 20.81 C ANISOU 556 CB GLU A 93 2686 2694 2526 123 38 -646 C ATOM 557 CG GLU A 93 -38.803 16.383 146.726 1.00 23.22 C ANISOU 557 CG GLU A 93 2995 3019 2808 119 33 -647 C ATOM 558 CD GLU A 93 -39.059 17.791 147.262 1.00 31.80 C ANISOU 558 CD GLU A 93 4085 4115 3883 118 41 -628 C ATOM 559 OE1 GLU A 93 -38.287 18.255 148.135 1.00 29.99 O ANISOU 559 OE1 GLU A 93 3856 3880 3659 119 53 -614 O ATOM 560 OE2 GLU A 93 -40.038 18.429 146.820 1.00 35.81 O ANISOU 560 OE2 GLU A 93 4594 4634 4377 117 33 -629 O ATOM 561 N GLY A 94 -35.331 13.675 147.680 1.00 28.21 N ANISOU 561 N GLY A 94 3617 3613 3489 140 46 -666 N ATOM 562 CA GLY A 94 -34.249 12.874 148.235 1.00 20.20 C ANISOU 562 CA GLY A 94 2596 2584 2493 151 47 -672 C ATOM 563 C GLY A 94 -34.027 13.130 149.721 1.00 18.82 C ANISOU 563 C GLY A 94 2421 2394 2336 153 45 -657 C ATOM 564 O GLY A 94 -34.070 14.264 150.197 1.00 17.98 O ANISOU 564 O GLY A 94 2315 2296 2220 148 52 -642 O ATOM 565 N ARG A 95 -33.756 12.051 150.450 1.00 19.11 N ANISOU 565 N ARG A 95 2461 2405 2396 161 36 -663 N ATOM 566 CA ARG A 95 -33.481 12.133 151.877 1.00 19.72 C ANISOU 566 CA ARG A 95 2542 2463 2488 165 31 -651 C ATOM 567 C ARG A 95 -32.093 12.700 152.153 1.00 19.41 C ANISOU 567 C ARG A 95 2491 2436 2449 175 36 -651 C ATOM 568 O ARG A 95 -31.200 12.691 151.301 1.00 22.10 O ANISOU 568 O ARG A 95 2817 2795 2785 181 44 -664 O ATOM 569 CB ARG A 95 -33.582 10.759 152.531 1.00 20.12 C ANISOU 569 CB ARG A 95 2603 2480 2562 172 17 -658 C ATOM 570 CG ARG A 95 -34.935 10.130 152.448 1.00 17.75 C ANISOU 570 CG ARG A 95 2313 2163 2267 161 12 -660 C ATOM 571 CD ARG A 95 -34.908 8.805 153.188 1.00 17.86 C ANISOU 571 CD ARG A 95 2341 2140 2304 167 0 -665 C ATOM 572 NE ARG A 95 -36.241 8.237 153.329 1.00 19.42 N ANISOU 572 NE ARG A 95 2549 2316 2511 153 -5 -668 N ATOM 573 CZ ARG A 95 -36.529 7.265 154.184 1.00 21.70 C ANISOU 573 CZ ARG A 95 2855 2568 2820 153 -13 -668 C ATOM 574 NH1 ARG A 95 -35.572 6.782 154.955 1.00 20.27 N ANISOU 574 NH1 ARG A 95 2685 2368 2649 168 -19 -664 N ATOM 575 NH2 ARG A 95 -37.763 6.785 154.279 1.00 23.92 N ANISOU 575 NH2 ARG A 95 3144 2831 3114 137 -15 -672 N ATOM 576 N ARG A 96 -31.919 13.194 153.380 1.00 18.43 N ANISOU 576 N ARG A 96 2372 2300 2330 176 32 -638 N ATOM 577 CA ARG A 96 -30.592 13.528 153.872 1.00 14.78 C ANISOU 577 CA ARG A 96 1898 1843 1876 186 30 -642 C ATOM 578 C ARG A 96 -29.639 12.358 153.658 1.00 21.32 C ANISOU 578 C ARG A 96 2715 2663 2724 204 22 -662 C ATOM 579 O ARG A 96 -30.003 11.203 153.879 1.00 21.27 O ANISOU 579 O ARG A 96 2720 2632 2730 210 11 -666 O ATOM 580 CB ARG A 96 -30.651 13.875 155.369 1.00 19.69 C ANISOU 580 CB ARG A 96 2534 2443 2502 187 19 -628 C ATOM 581 CG ARG A 96 -29.280 14.164 155.973 1.00 24.12 C ANISOU 581 CG ARG A 96 3083 3006 3074 199 11 -636 C ATOM 582 CD ARG A 96 -29.295 14.238 157.482 1.00 19.64 C ANISOU 582 CD ARG A 96 2538 2413 2513 204 -6 -625 C ATOM 583 NE ARG A 96 -29.830 15.496 157.947 1.00 32.44 N ANISOU 583 NE ARG A 96 4172 4040 4115 191 2 -608 N ATOM 584 CZ ARG A 96 -29.094 16.507 158.392 1.00 27.00 C ANISOU 584 CZ ARG A 96 3479 3360 3421 189 -2 -608 C ATOM 585 NH1 ARG A 96 -29.701 17.602 158.795 1.00 27.91 N ANISOU 585 NH1 ARG A 96 3610 3478 3517 176 6 -587 N ATOM 586 NH2 ARG A 96 -27.769 16.413 158.453 1.00 31.85 N ANISOU 586 NH2 ARG A 96 4071 3980 4050 200 -13 -623 N ATOM 587 N LYS A 97 -28.412 12.662 153.228 1.00 21.21 N ANISOU 587 N LYS A 97 2678 2670 2713 212 29 -676 N ATOM 588 CA LYS A 97 -27.378 11.631 153.122 1.00 30.47 C ANISOU 588 CA LYS A 97 3835 3835 3907 232 21 -697 C ATOM 589 C LYS A 97 -27.067 11.018 154.486 1.00 27.02 C ANISOU 589 C LYS A 97 3408 3366 3492 248 -3 -695 C ATOM 590 O LYS A 97 -27.012 11.715 155.503 1.00 25.96 O ANISOU 590 O LYS A 97 3280 3226 3357 245 -12 -683 O ATOM 591 CB LYS A 97 -26.094 12.211 152.532 1.00 37.72 C ANISOU 591 CB LYS A 97 4722 4783 4828 238 35 -714 C ATOM 592 CG LYS A 97 -26.239 12.809 151.140 1.00 52.66 C ANISOU 592 CG LYS A 97 6607 6705 6695 224 61 -717 C ATOM 593 CD LYS A 97 -24.873 13.166 150.538 1.00 61.38 C ANISOU 593 CD LYS A 97 7679 7837 7806 231 79 -737 C ATOM 594 CE LYS A 97 -23.738 12.328 151.142 1.00 64.32 C ANISOU 594 CE LYS A 97 8029 8198 8212 256 64 -757 C ATOM 595 NZ LYS A 97 -22.494 12.336 150.304 1.00 63.90 N ANISOU 595 NZ LYS A 97 7941 8170 8168 265 85 -781 N ATOM 596 N ARG A 98 -26.826 9.708 154.490 1.00 21.50 N ANISOU 596 N ARG A 98 2712 2647 2812 264 -15 -707 N ATOM 597 CA ARG A 98 -26.573 8.964 155.720 1.00 20.33 C ANISOU 597 CA ARG A 98 2578 2463 2683 281 -41 -704 C ATOM 598 C ARG A 98 -25.327 9.489 156.427 1.00 22.39 C ANISOU 598 C ARG A 98 2820 2730 2958 296 -54 -712 C ATOM 599 O ARG A 98 -24.232 9.478 155.861 1.00 25.42 O ANISOU 599 O ARG A 98 3170 3133 3354 310 -50 -733 O ATOM 600 CB ARG A 98 -26.423 7.477 155.387 1.00 20.26 C ANISOU 600 CB ARG A 98 2575 2433 2691 298 -50 -718 C ATOM 601 CG ARG A 98 -26.205 6.592 156.578 1.00 15.06 C ANISOU 601 CG ARG A 98 1936 1735 2051 316 -77 -715 C ATOM 602 CD ARG A 98 -26.084 5.146 156.140 1.00 18.63 C ANISOU 602 CD ARG A 98 2394 2165 2518 331 -84 -729 C ATOM 603 NE ARG A 98 -25.868 4.261 157.278 1.00 19.53 N ANISOU 603 NE ARG A 98 2532 2238 2649 350 -111 -724 N ATOM 604 CZ ARG A 98 -26.835 3.575 157.871 1.00 24.15 C ANISOU 604 CZ ARG A 98 3155 2787 3233 341 -118 -709 C ATOM 605 NH1 ARG A 98 -28.078 3.662 157.418 1.00 30.14 N ANISOU 605 NH1 ARG A 98 3927 3548 3977 314 -101 -701 N ATOM 606 NH2 ARG A 98 -26.561 2.795 158.903 1.00 17.96 N ANISOU 606 NH2 ARG A 98 2395 1965 2463 358 -144 -703 N ATOM 607 N THR A 99 -25.494 9.985 157.655 1.00 20.72 N ANISOU 607 N THR A 99 2628 2502 2744 294 -70 -697 N ATOM 608 CA THR A 99 -24.350 10.481 158.406 1.00 16.48 C ANISOU 608 CA THR A 99 2074 1966 2221 309 -89 -706 C ATOM 609 C THR A 99 -23.399 9.336 158.714 1.00 22.68 C ANISOU 609 C THR A 99 2851 2732 3036 341 -114 -723 C ATOM 610 O THR A 99 -23.818 8.251 159.132 1.00 26.24 O ANISOU 610 O THR A 99 3329 3150 3492 350 -128 -716 O ATOM 611 CB THR A 99 -24.802 11.165 159.701 1.00 19.42 C ANISOU 611 CB THR A 99 2478 2320 2581 301 -104 -685 C ATOM 612 OG1 THR A 99 -25.641 12.272 159.380 1.00 25.29 O ANISOU 612 OG1 THR A 99 3227 3083 3299 274 -80 -671 O ATOM 613 CG2 THR A 99 -23.603 11.661 160.517 1.00 16.11 C ANISOU 613 CG2 THR A 99 2044 1901 2175 314 -129 -689 C ATOM 614 N ALA A 100 -22.116 9.564 158.461 1.00 29.64 N ANISOU 614 N ALA A 100 3692 3633 3937 357 -118 -747 N ATOM 615 CA ALA A 100 -21.097 8.592 158.817 1.00 25.80 C ANISOU 615 CA ALA A 100 3192 3129 3482 391 -146 -765 C ATOM 616 C ALA A 100 -20.744 8.761 160.288 1.00 28.29 C ANISOU 616 C ALA A 100 3526 3416 3806 405 -185 -757 C ATOM 617 O ALA A 100 -20.509 9.879 160.757 1.00 34.34 O ANISOU 617 O ALA A 100 4286 4199 4564 388 -188 -742 O ATOM 618 CB ALA A 100 -19.860 8.773 157.941 1.00 26.73 C ANISOU 618 CB ALA A 100 3254 3280 3621 404 -133 -795 C ATOM 619 N VAL A 101 -20.741 7.658 161.024 1.00 23.45 N ANISOU 619 N VAL A 101 2941 2765 3205 427 -215 -751 N ATOM 620 CA VAL A 101 -20.383 7.673 162.434 1.00 26.26 C ANISOU 620 CA VAL A 101 3321 3091 3564 440 -256 -737 C ATOM 621 C VAL A 101 -19.201 6.730 162.622 1.00 29.65 C ANISOU 621 C VAL A 101 3730 3507 4031 481 -290 -758 C ATOM 622 O VAL A 101 -19.309 5.527 162.355 1.00 33.07 O ANISOU 622 O VAL A 101 4173 3919 4473 497 -292 -763 O ATOM 623 CB VAL A 101 -21.565 7.279 163.328 1.00 20.04 C ANISOU 623 CB VAL A 101 2596 2264 2754 430 -264 -708 C ATOM 624 CG1 VAL A 101 -21.211 7.527 164.786 1.00 19.83 C ANISOU 624 CG1 VAL A 101 2599 2214 2722 436 -303 -685 C ATOM 625 CG2 VAL A 101 -22.818 8.077 162.947 1.00 20.74 C ANISOU 625 CG2 VAL A 101 2700 2369 2812 393 -227 -691 C ATOM 626 N THR A 102 -18.064 7.280 163.038 1.00 30.51 N ANISOU 626 N THR A 102 3805 3631 4157 491 -313 -763 N ATOM 627 CA THR A 102 -16.881 6.460 163.224 1.00 30.04 C ANISOU 627 CA THR A 102 3718 3560 4136 532 -348 -784 C ATOM 628 C THR A 102 -17.066 5.554 164.435 1.00 30.14 C ANISOU 628 C THR A 102 3785 3520 4147 555 -392 -767 C ATOM 629 O THR A 102 -17.971 5.741 165.257 1.00 32.65 O ANISOU 629 O THR A 102 4157 3814 4434 536 -397 -736 O ATOM 630 CB THR A 102 -15.643 7.337 163.411 1.00 27.62 C ANISOU 630 CB THR A 102 3359 3284 3851 534 -364 -792 C ATOM 631 OG1 THR A 102 -15.765 8.061 164.644 1.00 31.47 O ANISOU 631 OG1 THR A 102 3879 3759 4319 519 -394 -763 O ATOM 632 CG2 THR A 102 -15.522 8.332 162.278 1.00 27.62 C ANISOU 632 CG2 THR A 102 3313 3334 3848 506 -317 -805 C ATOM 633 N GLY A 103 -16.188 4.559 164.552 1.00 32.15 N ANISOU 633 N GLY A 103 4026 3756 4436 597 -424 -787 N ATOM 634 CA GLY A 103 -16.187 3.751 165.758 1.00 23.17 C ANISOU 634 CA GLY A 103 2938 2567 3297 621 -472 -769 C ATOM 635 C GLY A 103 -15.889 4.574 166.992 1.00 28.81 C ANISOU 635 C GLY A 103 3671 3278 3998 613 -509 -744 C ATOM 636 O GLY A 103 -16.423 4.304 168.072 1.00 32.76 O ANISOU 636 O GLY A 103 4234 3739 4475 612 -534 -717 O ATOM 637 N SER A 104 -15.059 5.608 166.847 1.00 28.16 N ANISOU 637 N SER A 104 3535 3235 3928 604 -511 -753 N ATOM 638 CA SER A 104 -14.731 6.451 167.988 1.00 29.65 C ANISOU 638 CA SER A 104 3739 3422 4105 594 -548 -732 C ATOM 639 C SER A 104 -15.922 7.301 168.415 1.00 30.18 C ANISOU 639 C SER A 104 3857 3486 4123 552 -523 -700 C ATOM 640 O SER A 104 -16.186 7.462 169.614 1.00 31.70 O ANISOU 640 O SER A 104 4103 3651 4292 549 -554 -674 O ATOM 641 CB SER A 104 -13.552 7.347 167.653 1.00 32.16 C ANISOU 641 CB SER A 104 3985 3784 4452 591 -553 -752 C ATOM 642 OG SER A 104 -13.372 8.250 168.718 1.00 37.49 O ANISOU 642 OG SER A 104 4679 4456 5110 575 -586 -731 O ATOM 643 N GLN A 105 -16.636 7.877 167.455 1.00 30.09 N ANISOU 643 N GLN A 105 3830 3504 4098 521 -469 -702 N ATOM 644 CA GLN A 105 -17.834 8.626 167.800 1.00 26.55 C ANISOU 644 CA GLN A 105 3428 3052 3607 484 -444 -674 C ATOM 645 C GLN A 105 -18.884 7.714 168.437 1.00 22.43 C ANISOU 645 C GLN A 105 2976 2484 3062 488 -447 -652 C ATOM 646 O GLN A 105 -19.476 8.051 169.469 1.00 23.88 O ANISOU 646 O GLN A 105 3213 2646 3215 475 -457 -624 O ATOM 647 CB GLN A 105 -18.357 9.326 166.550 1.00 26.04 C ANISOU 647 CB GLN A 105 3332 3028 3535 455 -388 -682 C ATOM 648 CG GLN A 105 -17.433 10.451 166.085 1.00 26.20 C ANISOU 648 CG GLN A 105 3294 3092 3570 442 -382 -696 C ATOM 649 CD GLN A 105 -17.784 10.987 164.708 1.00 26.26 C ANISOU 649 CD GLN A 105 3267 3138 3573 418 -328 -708 C ATOM 650 OE1 GLN A 105 -18.103 10.226 163.796 1.00 25.72 O ANISOU 650 OE1 GLN A 105 3190 3071 3511 427 -303 -724 O ATOM 651 NE2 GLN A 105 -17.735 12.311 164.556 1.00 25.67 N ANISOU 651 NE2 GLN A 105 3176 3092 3486 388 -311 -700 N ATOM 652 N THR A 106 -19.101 6.536 167.853 1.00 24.96 N ANISOU 652 N THR A 106 3297 2787 3398 506 -438 -666 N ATOM 653 CA THR A 106 -20.090 5.606 168.398 1.00 22.85 C ANISOU 653 CA THR A 106 3094 2475 3113 508 -438 -647 C ATOM 654 C THR A 106 -19.780 5.247 169.845 1.00 25.52 C ANISOU 654 C THR A 106 3483 2772 3442 527 -488 -626 C ATOM 655 O THR A 106 -20.668 5.280 170.706 1.00 24.77 O ANISOU 655 O THR A 106 3449 2649 3314 511 -485 -596 O ATOM 656 CB THR A 106 -20.159 4.341 167.542 1.00 23.57 C ANISOU 656 CB THR A 106 3175 2551 3227 528 -429 -669 C ATOM 657 OG1 THR A 106 -20.627 4.675 166.230 1.00 24.34 O ANISOU 657 OG1 THR A 106 3237 2686 3326 506 -380 -685 O ATOM 658 CG2 THR A 106 -21.117 3.325 168.167 1.00 25.44 C ANISOU 658 CG2 THR A 106 3478 2742 3447 524 -430 -643 C ATOM 659 N ALA A 107 -18.519 4.907 170.134 1.00 25.80 N ANISOU 659 N ALA A 107 3495 2802 3505 562 -535 -641 N ATOM 660 CA ALA A 107 -18.159 4.512 171.494 1.00 29.59 C ANISOU 660 CA ALA A 107 4026 3242 3977 584 -588 -622 C ATOM 661 C ALA A 107 -18.412 5.645 172.476 1.00 29.77 C ANISOU 661 C ALA A 107 4081 3268 3962 559 -597 -595 C ATOM 662 O ALA A 107 -18.794 5.416 173.630 1.00 23.81 O ANISOU 662 O ALA A 107 3394 2475 3178 561 -619 -568 O ATOM 663 CB ALA A 107 -16.696 4.082 171.548 1.00 33.40 C ANISOU 663 CB ALA A 107 4466 3724 4499 627 -639 -646 C ATOM 664 N LEU A 108 -18.205 6.880 172.035 1.00 27.34 N ANISOU 664 N LEU A 108 3728 3005 3654 535 -577 -602 N ATOM 665 CA LEU A 108 -18.448 8.007 172.918 1.00 22.63 C ANISOU 665 CA LEU A 108 3163 2412 3024 511 -583 -580 C ATOM 666 C LEU A 108 -19.940 8.158 173.195 1.00 22.67 C ANISOU 666 C LEU A 108 3226 2401 2986 482 -542 -552 C ATOM 667 O LEU A 108 -20.353 8.342 174.347 1.00 25.18 O ANISOU 667 O LEU A 108 3606 2691 3269 476 -556 -526 O ATOM 668 CB LEU A 108 -17.855 9.270 172.298 1.00 28.87 C ANISOU 668 CB LEU A 108 3891 3252 3826 491 -571 -595 C ATOM 669 CG LEU A 108 -17.501 10.401 173.254 1.00 36.93 C ANISOU 669 CG LEU A 108 4929 4277 4826 477 -599 -582 C ATOM 670 CD1 LEU A 108 -16.414 11.246 172.625 1.00 38.54 C ANISOU 670 CD1 LEU A 108 5057 4524 5062 471 -605 -606 C ATOM 671 CD2 LEU A 108 -18.735 11.231 173.538 1.00 37.83 C ANISOU 671 CD2 LEU A 108 5089 4391 4896 442 -560 -556 C ATOM 672 N LEU A 109 -20.767 8.065 172.149 1.00 22.64 N ANISOU 672 N LEU A 109 3203 2414 2986 463 -490 -558 N ATOM 673 CA LEU A 109 -22.212 8.126 172.348 1.00 21.66 C ANISOU 673 CA LEU A 109 3127 2276 2828 437 -450 -534 C ATOM 674 C LEU A 109 -22.705 6.963 173.201 1.00 14.64 C ANISOU 674 C LEU A 109 2302 1333 1926 450 -465 -515 C ATOM 675 O LEU A 109 -23.591 7.136 174.042 1.00 20.16 O ANISOU 675 O LEU A 109 3059 2010 2590 434 -452 -487 O ATOM 676 CB LEU A 109 -22.928 8.138 170.998 1.00 23.69 C ANISOU 676 CB LEU A 109 3346 2561 3096 418 -399 -548 C ATOM 677 CG LEU A 109 -22.590 9.332 170.113 1.00 21.88 C ANISOU 677 CG LEU A 109 3059 2382 2873 401 -377 -563 C ATOM 678 CD1 LEU A 109 -22.806 9.038 168.669 1.00 15.21 C ANISOU 678 CD1 LEU A 109 2169 1562 2048 396 -343 -586 C ATOM 679 CD2 LEU A 109 -23.428 10.519 170.550 1.00 27.39 C ANISOU 679 CD2 LEU A 109 3782 3089 3535 370 -353 -540 C ATOM 680 N LEU A 110 -22.157 5.768 172.983 1.00 15.43 N ANISOU 680 N LEU A 110 2397 1412 2055 480 -490 -529 N ATOM 681 CA LEU A 110 -22.592 4.614 173.761 1.00 23.95 C ANISOU 681 CA LEU A 110 3540 2437 3122 493 -505 -511 C ATOM 682 C LEU A 110 -22.306 4.807 175.246 1.00 30.84 C ANISOU 682 C LEU A 110 4473 3280 3965 502 -545 -486 C ATOM 683 O LEU A 110 -23.159 4.512 176.091 1.00 30.03 O ANISOU 683 O LEU A 110 4438 3141 3829 491 -536 -457 O ATOM 684 CB LEU A 110 -21.923 3.351 173.235 1.00 25.97 C ANISOU 684 CB LEU A 110 3777 2675 3416 527 -528 -534 C ATOM 685 CG LEU A 110 -22.471 2.016 173.734 1.00 38.51 C ANISOU 685 CG LEU A 110 5422 4212 4996 534 -532 -513 C ATOM 686 CD1 LEU A 110 -23.980 2.055 173.862 1.00 38.97 C ANISOU 686 CD1 LEU A 110 5522 4260 5026 495 -483 -488 C ATOM 687 CD2 LEU A 110 -22.041 0.896 172.788 1.00 38.66 C ANISOU 687 CD2 LEU A 110 5403 4232 5052 553 -533 -535 C ATOM 688 N ARG A 111 -21.126 5.331 175.588 1.00 29.82 N ANISOU 688 N ARG A 111 4320 3165 3846 521 -591 -496 N ATOM 689 CA ARG A 111 -20.842 5.606 176.994 1.00 28.51 C ANISOU 689 CA ARG A 111 4212 2973 3648 529 -633 -473 C ATOM 690 C ARG A 111 -21.849 6.583 177.577 1.00 26.49 C ANISOU 690 C ARG A 111 3998 2721 3346 494 -598 -447 C ATOM 691 O ARG A 111 -22.338 6.386 178.692 1.00 26.51 O ANISOU 691 O ARG A 111 4076 2687 3311 492 -606 -420 O ATOM 692 CB ARG A 111 -19.413 6.128 177.165 1.00 33.15 C ANISOU 692 CB ARG A 111 4757 3580 4257 551 -687 -492 C ATOM 693 CG ARG A 111 -18.352 5.029 177.019 1.00 41.39 C ANISOU 693 CG ARG A 111 5777 4607 5342 596 -735 -511 C ATOM 694 CD ARG A 111 -16.959 5.532 177.377 1.00 51.05 C ANISOU 694 CD ARG A 111 6964 5847 6586 618 -795 -527 C ATOM 695 NE ARG A 111 -16.469 6.512 176.413 1.00 57.31 N ANISOU 695 NE ARG A 111 7673 6695 7406 601 -773 -552 N ATOM 696 CZ ARG A 111 -15.787 6.194 175.316 1.00 56.90 C ANISOU 696 CZ ARG A 111 7547 6671 7403 616 -766 -583 C ATOM 697 NH1 ARG A 111 -15.511 4.918 175.057 1.00 57.72 N ANISOU 697 NH1 ARG A 111 7648 6749 7533 651 -781 -595 N ATOM 698 NH2 ARG A 111 -15.376 7.146 174.481 1.00 48.58 N ANISOU 698 NH2 ARG A 111 6423 5666 6368 597 -742 -603 N ATOM 699 N ALA A 112 -22.197 7.633 176.833 1.00 21.45 N ANISOU 699 N ALA A 112 3316 2126 2709 466 -557 -456 N ATOM 700 CA ALA A 112 -23.186 8.567 177.353 1.00 22.63 C ANISOU 700 CA ALA A 112 3503 2279 2816 435 -522 -433 C ATOM 701 C ALA A 112 -24.547 7.905 177.477 1.00 22.61 C ANISOU 701 C ALA A 112 3547 2249 2794 419 -478 -412 C ATOM 702 O ALA A 112 -25.277 8.146 178.449 1.00 21.20 O ANISOU 702 O ALA A 112 3432 2049 2576 406 -465 -385 O ATOM 703 CB ALA A 112 -23.275 9.802 176.456 1.00 24.04 C ANISOU 703 CB ALA A 112 3623 2508 3003 410 -489 -447 C ATOM 704 N PHE A 113 -24.908 7.080 176.487 1.00 19.40 N ANISOU 704 N PHE A 113 3110 1844 2416 419 -453 -425 N ATOM 705 CA PHE A 113 -26.208 6.413 176.495 1.00 24.64 C ANISOU 705 CA PHE A 113 3810 2484 3068 400 -411 -407 C ATOM 706 C PHE A 113 -26.366 5.513 177.715 1.00 23.21 C ANISOU 706 C PHE A 113 3709 2247 2863 412 -433 -381 C ATOM 707 O PHE A 113 -27.444 5.460 178.320 1.00 26.03 O ANISOU 707 O PHE A 113 4118 2583 3190 392 -399 -355 O ATOM 708 CB PHE A 113 -26.373 5.602 175.208 1.00 24.14 C ANISOU 708 CB PHE A 113 3700 2430 3043 402 -392 -430 C ATOM 709 CG PHE A 113 -27.733 5.005 175.035 1.00 24.19 C ANISOU 709 CG PHE A 113 3730 2417 3042 378 -346 -416 C ATOM 710 CD1 PHE A 113 -28.792 5.780 174.571 1.00 20.82 C ANISOU 710 CD1 PHE A 113 3286 2019 2606 346 -296 -411 C ATOM 711 CD2 PHE A 113 -27.953 3.660 175.300 1.00 24.84 C ANISOU 711 CD2 PHE A 113 3853 2454 3132 387 -355 -408 C ATOM 712 CE1 PHE A 113 -30.049 5.223 174.388 1.00 19.90 C ANISOU 712 CE1 PHE A 113 3186 1886 2488 323 -256 -400 C ATOM 713 CE2 PHE A 113 -29.204 3.107 175.121 1.00 25.39 C ANISOU 713 CE2 PHE A 113 3942 2506 3200 362 -313 -396 C ATOM 714 CZ PHE A 113 -30.256 3.895 174.662 1.00 24.03 C ANISOU 714 CZ PHE A 113 3747 2364 3019 329 -263 -393 C ATOM 715 N GLU A 114 -25.302 4.801 178.087 1.00 22.00 N ANISOU 715 N GLU A 114 3567 2070 2723 447 -488 -388 N ATOM 716 CA GLU A 114 -25.343 3.945 179.270 1.00 27.88 C ANISOU 716 CA GLU A 114 4391 2759 3442 461 -516 -362 C ATOM 717 C GLU A 114 -25.623 4.726 180.545 1.00 33.86 C ANISOU 717 C GLU A 114 5212 3505 4148 451 -518 -335 C ATOM 718 O GLU A 114 -26.230 4.182 181.476 1.00 39.51 O ANISOU 718 O GLU A 114 6003 4178 4832 447 -512 -306 O ATOM 719 CB GLU A 114 -24.029 3.185 179.417 1.00 26.75 C ANISOU 719 CB GLU A 114 4243 2596 3324 504 -582 -376 C ATOM 720 CG GLU A 114 -23.964 1.911 178.608 1.00 42.54 C ANISOU 720 CG GLU A 114 6214 4588 5361 515 -578 -388 C ATOM 721 CD GLU A 114 -22.590 1.674 178.005 1.00 60.35 C ANISOU 721 CD GLU A 114 8409 6860 7659 552 -624 -421 C ATOM 722 OE1 GLU A 114 -22.532 1.275 176.825 1.00 67.88 O ANISOU 722 OE1 GLU A 114 9306 7835 8649 553 -603 -445 O ATOM 723 OE2 GLU A 114 -21.569 1.895 178.699 1.00 64.64 O ANISOU 723 OE2 GLU A 114 8963 7396 8201 580 -681 -423 O ATOM 724 N LYS A 115 -25.182 5.986 180.623 1.00 31.91 N ANISOU 724 N LYS A 115 4939 3294 3892 446 -528 -342 N ATOM 725 CA LYS A 115 -25.457 6.778 181.821 1.00 28.81 C ANISOU 725 CA LYS A 115 4609 2890 3449 436 -529 -318 C ATOM 726 C LYS A 115 -26.853 7.379 181.792 1.00 34.63 C ANISOU 726 C LYS A 115 5360 3637 4160 399 -460 -302 C ATOM 727 O LYS A 115 -27.537 7.410 182.820 1.00 35.98 O ANISOU 727 O LYS A 115 5603 3780 4287 390 -443 -275 O ATOM 728 CB LYS A 115 -24.423 7.890 181.980 1.00 33.56 C ANISOU 728 CB LYS A 115 5181 3521 4050 444 -570 -333 C ATOM 729 CG LYS A 115 -22.992 7.422 181.853 1.00 52.81 C ANISOU 729 CG LYS A 115 7585 5958 6523 479 -637 -354 C ATOM 730 CD LYS A 115 -22.101 8.050 182.918 1.00 64.16 C ANISOU 730 CD LYS A 115 9055 7387 7936 493 -697 -351 C ATOM 731 CE LYS A 115 -20.680 7.487 182.848 1.00 71.40 C ANISOU 731 CE LYS A 115 9938 8301 8891 531 -768 -371 C ATOM 732 NZ LYS A 115 -20.654 5.994 182.953 1.00 73.35 N ANISOU 732 NZ LYS A 115 10215 8506 9150 558 -786 -365 N ATOM 733 N ASP A 116 -27.292 7.866 180.631 1.00 27.74 N ANISOU 733 N ASP A 116 4421 2806 3314 380 -418 -319 N ATOM 734 CA ASP A 116 -28.558 8.584 180.538 1.00 28.11 C ANISOU 734 CA ASP A 116 4472 2868 3341 348 -356 -307 C ATOM 735 C ASP A 116 -29.082 8.457 179.115 1.00 27.48 C ANISOU 735 C ASP A 116 4323 2820 3300 333 -317 -325 C ATOM 736 O ASP A 116 -28.418 8.875 178.159 1.00 25.67 O ANISOU 736 O ASP A 116 4028 2625 3099 338 -329 -351 O ATOM 737 CB ASP A 116 -28.367 10.055 180.935 1.00 31.51 C ANISOU 737 CB ASP A 116 4902 3324 3745 340 -358 -307 C ATOM 738 CG ASP A 116 -29.663 10.840 180.925 1.00 39.32 C ANISOU 738 CG ASP A 116 5900 4328 4713 312 -295 -294 C ATOM 739 OD1 ASP A 116 -30.741 10.209 180.917 1.00 41.97 O ANISOU 739 OD1 ASP A 116 6254 4646 5045 298 -252 -279 O ATOM 740 OD2 ASP A 116 -29.601 12.091 180.963 1.00 42.66 O ANISOU 740 OD2 ASP A 116 6311 4776 5121 304 -289 -298 O ATOM 741 N ARG A 117 -30.261 7.868 178.971 1.00 23.07 N ANISOU 741 N ARG A 117 3779 2246 2740 314 -272 -312 N ATOM 742 CA ARG A 117 -30.836 7.640 177.653 1.00 26.57 C ANISOU 742 CA ARG A 117 4162 2714 3218 300 -238 -329 C ATOM 743 C ARG A 117 -31.614 8.835 177.123 1.00 22.11 C ANISOU 743 C ARG A 117 3563 2190 2648 276 -194 -332 C ATOM 744 O ARG A 117 -32.020 8.815 175.955 1.00 22.60 O ANISOU 744 O ARG A 117 3571 2278 2737 265 -170 -348 O ATOM 745 CB ARG A 117 -31.767 6.426 177.684 1.00 27.61 C ANISOU 745 CB ARG A 117 4322 2811 3356 288 -211 -316 C ATOM 746 CG ARG A 117 -31.134 5.179 178.280 1.00 35.80 C ANISOU 746 CG ARG A 117 5406 3802 4396 311 -252 -310 C ATOM 747 CD ARG A 117 -31.917 3.958 177.859 1.00 37.59 C ANISOU 747 CD ARG A 117 5638 4001 4643 299 -227 -307 C ATOM 748 NE ARG A 117 -33.355 4.161 178.005 1.00 40.61 N ANISOU 748 NE ARG A 117 6035 4383 5012 264 -169 -288 N ATOM 749 CZ ARG A 117 -34.275 3.529 177.279 1.00 42.50 C ANISOU 749 CZ ARG A 117 6252 4619 5275 242 -134 -292 C ATOM 750 NH1 ARG A 117 -33.908 2.646 176.338 1.00 34.35 N ANISOU 750 NH1 ARG A 117 5188 3584 4281 252 -153 -315 N ATOM 751 NH2 ARG A 117 -35.563 3.790 177.486 1.00 46.51 N ANISOU 751 NH2 ARG A 117 6770 5129 5772 211 -82 -274 N ATOM 752 N PHE A 118 -31.851 9.854 177.951 1.00 20.00 N ANISOU 752 N PHE A 118 3327 1926 2345 269 -183 -316 N ATOM 753 CA PHE A 118 -32.669 11.006 177.586 1.00 18.85 C ANISOU 753 CA PHE A 118 3157 1813 2191 248 -141 -315 C ATOM 754 C PHE A 118 -31.902 12.310 177.834 1.00 22.27 C ANISOU 754 C PHE A 118 3585 2269 2608 254 -163 -321 C ATOM 755 O PHE A 118 -32.334 13.149 178.621 1.00 24.91 O ANISOU 755 O PHE A 118 3955 2600 2909 247 -147 -306 O ATOM 756 CB PHE A 118 -33.973 10.998 178.383 1.00 21.07 C ANISOU 756 CB PHE A 118 3486 2073 2445 230 -94 -288 C ATOM 757 CG PHE A 118 -34.881 9.844 178.046 1.00 25.67 C ANISOU 757 CG PHE A 118 4069 2638 3048 217 -65 -282 C ATOM 758 CD1 PHE A 118 -34.761 8.642 178.704 1.00 15.03 C ANISOU 758 CD1 PHE A 118 2769 1246 1695 224 -80 -269 C ATOM 759 CD2 PHE A 118 -35.860 9.971 177.065 1.00 17.11 C ANISOU 759 CD2 PHE A 118 2935 1578 1986 197 -24 -290 C ATOM 760 CE1 PHE A 118 -35.588 7.583 178.392 1.00 21.02 C ANISOU 760 CE1 PHE A 118 3529 1985 2474 208 -53 -264 C ATOM 761 CE2 PHE A 118 -36.697 8.910 176.742 1.00 18.97 C ANISOU 761 CE2 PHE A 118 3168 1796 2243 182 1 -286 C ATOM 762 CZ PHE A 118 -36.563 7.716 177.405 1.00 19.80 C ANISOU 762 CZ PHE A 118 3322 1856 2344 186 -13 -273 C ATOM 763 N PRO A 119 -30.761 12.501 177.158 1.00 19.16 N ANISOU 763 N PRO A 119 3144 1898 2239 267 -200 -345 N ATOM 764 CA PRO A 119 -30.003 13.749 177.381 1.00 15.09 C ANISOU 764 CA PRO A 119 2621 1402 1710 269 -222 -351 C ATOM 765 C PRO A 119 -30.804 14.960 176.947 1.00 19.63 C ANISOU 765 C PRO A 119 3176 2007 2276 249 -180 -350 C ATOM 766 O PRO A 119 -31.484 14.941 175.921 1.00 19.06 O ANISOU 766 O PRO A 119 3062 1957 2224 237 -146 -357 O ATOM 767 CB PRO A 119 -28.759 13.571 176.498 1.00 18.54 C ANISOU 767 CB PRO A 119 2999 1861 2184 283 -259 -378 C ATOM 768 CG PRO A 119 -29.195 12.626 175.420 1.00 16.61 C ANISOU 768 CG PRO A 119 2717 1622 1971 281 -237 -389 C ATOM 769 CD PRO A 119 -30.138 11.665 176.120 1.00 16.49 C ANISOU 769 CD PRO A 119 2755 1568 1941 278 -218 -367 C ATOM 770 N GLY A 120 -30.712 16.031 177.743 1.00 12.93 N ANISOU 770 N GLY A 120 2360 1158 1397 246 -184 -341 N ATOM 771 CA GLY A 120 -31.312 17.297 177.389 1.00 13.51 C ANISOU 771 CA GLY A 120 2417 1256 1460 231 -151 -341 C ATOM 772 C GLY A 120 -30.461 18.032 176.384 1.00 15.59 C ANISOU 772 C GLY A 120 2621 1555 1748 229 -168 -363 C ATOM 773 O GLY A 120 -29.428 17.543 175.933 1.00 18.66 O ANISOU 773 O GLY A 120 2977 1950 2162 239 -202 -379 O ATOM 774 N ILE A 121 -30.893 19.253 176.048 1.00 16.13 N ANISOU 774 N ILE A 121 2676 1645 1807 216 -142 -363 N ATOM 775 CA ILE A 121 -30.221 19.985 174.979 1.00 14.56 C ANISOU 775 CA ILE A 121 2421 1480 1630 209 -150 -382 C ATOM 776 C ILE A 121 -28.757 20.213 175.328 1.00 19.04 C ANISOU 776 C ILE A 121 2985 2047 2203 217 -201 -393 C ATOM 777 O ILE A 121 -27.872 20.053 174.477 1.00 16.71 O ANISOU 777 O ILE A 121 2638 1773 1939 219 -220 -412 O ATOM 778 CB ILE A 121 -30.959 21.305 174.669 1.00 22.63 C ANISOU 778 CB ILE A 121 3439 2521 2637 195 -116 -377 C ATOM 779 CG1 ILE A 121 -30.232 22.093 173.566 1.00 16.13 C ANISOU 779 CG1 ILE A 121 2563 1731 1835 187 -123 -395 C ATOM 780 CG2 ILE A 121 -31.123 22.152 175.932 1.00 22.37 C ANISOU 780 CG2 ILE A 121 3466 2467 2566 195 -118 -363 C ATOM 781 CD1 ILE A 121 -30.102 21.351 172.224 1.00 19.07 C ANISOU 781 CD1 ILE A 121 2878 2126 2242 187 -116 -410 C ATOM 782 N ALA A 122 -28.466 20.564 176.589 1.00 17.17 N ANISOU 782 N ALA A 122 2801 1786 1937 222 -226 -383 N ATOM 783 CA ALA A 122 -27.081 20.872 176.940 1.00 17.99 C ANISOU 783 CA ALA A 122 2899 1890 2047 227 -279 -395 C ATOM 784 C ALA A 122 -26.208 19.629 176.856 1.00 14.17 C ANISOU 784 C ALA A 122 2395 1398 1591 246 -317 -405 C ATOM 785 O ALA A 122 -25.078 19.680 176.347 1.00 21.17 O ANISOU 785 O ALA A 122 3234 2303 2507 249 -347 -424 O ATOM 786 CB ALA A 122 -27.008 21.484 178.342 1.00 18.26 C ANISOU 786 CB ALA A 122 3000 1897 2040 229 -301 -383 C ATOM 787 N ALA A 123 -26.720 18.494 177.330 1.00 17.12 N ANISOU 787 N ALA A 123 2803 1746 1957 258 -313 -394 N ATOM 788 CA ALA A 123 -25.984 17.244 177.171 1.00 14.22 C ANISOU 788 CA ALA A 123 2418 1368 1618 277 -345 -403 C ATOM 789 C ALA A 123 -25.803 16.884 175.693 1.00 15.65 C ANISOU 789 C ALA A 123 2525 1580 1840 276 -328 -424 C ATOM 790 O ALA A 123 -24.744 16.386 175.296 1.00 17.04 O ANISOU 790 O ALA A 123 2663 1763 2047 290 -361 -442 O ATOM 791 CB ALA A 123 -26.697 16.120 177.923 1.00 18.54 C ANISOU 791 CB ALA A 123 3020 1878 2147 288 -339 -384 C ATOM 792 N ARG A 124 -26.814 17.138 174.850 1.00 14.70 N ANISOU 792 N ARG A 124 2385 1478 1721 259 -278 -422 N ATOM 793 CA ARG A 124 -26.645 16.797 173.431 1.00 12.97 C ANISOU 793 CA ARG A 124 2102 1287 1537 258 -263 -442 C ATOM 794 C ARG A 124 -25.649 17.728 172.749 1.00 10.16 C ANISOU 794 C ARG A 124 1696 965 1199 251 -275 -460 C ATOM 795 O ARG A 124 -24.852 17.286 171.908 1.00 15.29 O ANISOU 795 O ARG A 124 2296 1632 1881 259 -286 -481 O ATOM 796 CB ARG A 124 -27.990 16.821 172.689 1.00 13.62 C ANISOU 796 CB ARG A 124 2178 1381 1616 243 -210 -436 C ATOM 797 CG ARG A 124 -28.998 15.791 173.218 1.00 16.68 C ANISOU 797 CG ARG A 124 2606 1738 1994 246 -194 -420 C ATOM 798 CD ARG A 124 -30.201 15.626 172.297 1.00 11.53 C ANISOU 798 CD ARG A 124 1933 1099 1349 232 -148 -420 C ATOM 799 NE ARG A 124 -30.877 16.881 171.983 1.00 11.73 N ANISOU 799 NE ARG A 124 1949 1147 1360 215 -117 -414 N ATOM 800 CZ ARG A 124 -31.895 17.360 172.684 1.00 12.74 C ANISOU 800 CZ ARG A 124 2115 1264 1462 206 -91 -394 C ATOM 801 NH1 ARG A 124 -32.352 16.680 173.722 1.00 12.75 N ANISOU 801 NH1 ARG A 124 2164 1231 1447 210 -89 -377 N ATOM 802 NH2 ARG A 124 -32.473 18.497 172.340 1.00 16.17 N ANISOU 802 NH2 ARG A 124 2539 1720 1886 194 -64 -391 N ATOM 803 N GLU A 125 -25.673 19.023 173.100 1.00 16.02 N ANISOU 803 N GLU A 125 2451 1715 1920 236 -272 -453 N ATOM 804 CA GLU A 125 -24.687 19.959 172.556 1.00 14.31 C ANISOU 804 CA GLU A 125 2191 1526 1720 226 -285 -469 C ATOM 805 C GLU A 125 -23.281 19.610 173.008 1.00 15.27 C ANISOU 805 C GLU A 125 2298 1643 1862 241 -338 -482 C ATOM 806 O GLU A 125 -22.321 19.790 172.249 1.00 15.44 O ANISOU 806 O GLU A 125 2263 1689 1913 239 -348 -501 O ATOM 807 CB GLU A 125 -25.008 21.387 172.985 1.00 11.18 C ANISOU 807 CB GLU A 125 1821 1132 1295 208 -275 -458 C ATOM 808 CG GLU A 125 -26.301 21.912 172.402 1.00 19.23 C ANISOU 808 CG GLU A 125 2845 2163 2299 194 -223 -447 C ATOM 809 CD GLU A 125 -26.193 22.303 170.932 1.00 24.49 C ANISOU 809 CD GLU A 125 3453 2864 2986 181 -198 -461 C ATOM 810 OE1 GLU A 125 -25.074 22.289 170.368 1.00 23.46 O ANISOU 810 OE1 GLU A 125 3280 2753 2883 181 -217 -479 O ATOM 811 OE2 GLU A 125 -27.250 22.630 170.344 1.00 28.26 O ANISOU 811 OE2 GLU A 125 3931 3352 3454 173 -160 -454 O ATOM 812 N GLU A 126 -23.128 19.144 174.254 1.00 13.70 N ANISOU 812 N GLU A 126 2148 1410 1646 256 -373 -471 N ATOM 813 CA GLU A 126 -21.811 18.657 174.675 1.00 16.60 C ANISOU 813 CA GLU A 126 2500 1770 2036 275 -429 -484 C ATOM 814 C GLU A 126 -21.363 17.491 173.801 1.00 23.27 C ANISOU 814 C GLU A 126 3297 2625 2921 294 -430 -502 C ATOM 815 O GLU A 126 -20.215 17.445 173.341 1.00 19.11 O ANISOU 815 O GLU A 126 2716 2115 2428 301 -455 -523 O ATOM 816 CB GLU A 126 -21.826 18.247 176.153 1.00 13.19 C ANISOU 816 CB GLU A 126 2137 1298 1576 291 -467 -468 C ATOM 817 CG GLU A 126 -20.590 17.433 176.535 1.00 20.62 C ANISOU 817 CG GLU A 126 3064 2227 2543 318 -526 -480 C ATOM 818 CD GLU A 126 -20.220 17.511 178.003 1.00 31.71 C ANISOU 818 CD GLU A 126 4529 3599 3919 329 -578 -468 C ATOM 819 OE1 GLU A 126 -21.130 17.545 178.855 1.00 34.98 O ANISOU 819 OE1 GLU A 126 5014 3987 4290 326 -564 -446 O ATOM 820 OE2 GLU A 126 -19.000 17.545 178.302 1.00 32.20 O ANISOU 820 OE2 GLU A 126 4569 3663 4003 340 -633 -482 O ATOM 821 N LEU A 127 -22.268 16.549 173.533 1.00 21.49 N ANISOU 821 N LEU A 127 3088 2386 2692 301 -403 -495 N ATOM 822 CA LEU A 127 -21.904 15.412 172.700 1.00 16.48 C ANISOU 822 CA LEU A 127 2413 1757 2092 319 -403 -513 C ATOM 823 C LEU A 127 -21.649 15.840 171.260 1.00 11.31 C ANISOU 823 C LEU A 127 1690 1143 1462 307 -373 -534 C ATOM 824 O LEU A 127 -20.769 15.288 170.593 1.00 18.66 O ANISOU 824 O LEU A 127 2573 2088 2428 322 -385 -556 O ATOM 825 CB LEU A 127 -23.010 14.366 172.768 1.00 16.45 C ANISOU 825 CB LEU A 127 2447 1727 2077 325 -380 -501 C ATOM 826 CG LEU A 127 -23.180 13.696 174.124 1.00 23.09 C ANISOU 826 CG LEU A 127 3355 2523 2895 340 -409 -481 C ATOM 827 CD1 LEU A 127 -24.405 12.765 174.106 1.00 19.40 C ANISOU 827 CD1 LEU A 127 2922 2031 2416 338 -377 -466 C ATOM 828 CD2 LEU A 127 -21.893 12.946 174.485 1.00 23.95 C ANISOU 828 CD2 LEU A 127 3452 2618 3029 370 -466 -494 C ATOM 829 N ALA A 128 -22.444 16.783 170.737 1.00 12.31 N ANISOU 829 N ALA A 128 1816 1290 1572 281 -331 -527 N ATOM 830 CA ALA A 128 -22.136 17.318 169.409 1.00 16.56 C ANISOU 830 CA ALA A 128 2296 1868 2129 267 -304 -545 C ATOM 831 C ALA A 128 -20.746 17.944 169.379 1.00 17.38 C ANISOU 831 C ALA A 128 2358 1991 2256 266 -332 -560 C ATOM 832 O ALA A 128 -19.967 17.703 168.449 1.00 19.36 O ANISOU 832 O ALA A 128 2553 2266 2538 271 -328 -582 O ATOM 833 CB ALA A 128 -23.187 18.339 168.992 1.00 15.86 C ANISOU 833 CB ALA A 128 2218 1793 2014 241 -261 -532 C ATOM 834 N ARG A 129 -20.406 18.726 170.407 1.00 19.84 N ANISOU 834 N ARG A 129 2695 2290 2552 259 -362 -550 N ATOM 835 CA ARG A 129 -19.075 19.327 170.469 1.00 19.00 C ANISOU 835 CA ARG A 129 2549 2200 2469 255 -393 -564 C ATOM 836 C ARG A 129 -17.992 18.261 170.505 1.00 16.13 C ANISOU 836 C ARG A 129 2152 1834 2144 284 -431 -583 C ATOM 837 O ARG A 129 -17.033 18.308 169.731 1.00 22.32 O ANISOU 837 O ARG A 129 2873 2645 2963 285 -431 -605 O ATOM 838 CB ARG A 129 -18.957 20.238 171.690 1.00 23.34 C ANISOU 838 CB ARG A 129 3143 2733 2995 244 -424 -550 C ATOM 839 CG ARG A 129 -17.494 20.623 171.984 1.00 24.80 C ANISOU 839 CG ARG A 129 3288 2926 3207 244 -471 -566 C ATOM 840 CD ARG A 129 -17.376 21.624 173.096 1.00 18.56 C ANISOU 840 CD ARG A 129 2541 2120 2392 230 -502 -554 C ATOM 841 NE ARG A 129 -17.963 21.176 174.352 1.00 20.43 N ANISOU 841 NE ARG A 129 2851 2318 2593 246 -526 -535 N ATOM 842 CZ ARG A 129 -17.386 20.324 175.198 1.00 19.18 C ANISOU 842 CZ ARG A 129 2710 2136 2442 273 -577 -537 C ATOM 843 NH1 ARG A 129 -17.998 20.005 176.331 1.00 15.69 N ANISOU 843 NH1 ARG A 129 2342 1658 1961 284 -593 -517 N ATOM 844 NH2 ARG A 129 -16.213 19.779 174.910 1.00 22.37 N ANISOU 844 NH2 ARG A 129 3058 2551 2889 289 -611 -558 N ATOM 845 N GLU A 130 -18.139 17.274 171.389 1.00 17.54 N ANISOU 845 N GLU A 130 2372 1978 2316 310 -462 -575 N ATOM 846 CA GLU A 130 -17.092 16.269 171.549 1.00 20.29 C ANISOU 846 CA GLU A 130 2693 2318 2699 342 -504 -592 C ATOM 847 C GLU A 130 -16.954 15.372 170.320 1.00 24.16 C ANISOU 847 C GLU A 130 3133 2825 3220 356 -477 -613 C ATOM 848 O GLU A 130 -15.843 14.941 169.992 1.00 20.49 O ANISOU 848 O GLU A 130 2616 2373 2796 376 -499 -636 O ATOM 849 CB GLU A 130 -17.368 15.423 172.783 1.00 21.08 C ANISOU 849 CB GLU A 130 2856 2373 2778 365 -542 -576 C ATOM 850 CG GLU A 130 -17.314 16.190 174.085 1.00 24.49 C ANISOU 850 CG GLU A 130 3340 2786 3180 357 -578 -558 C ATOM 851 CD GLU A 130 -17.796 15.346 175.241 1.00 34.35 C ANISOU 851 CD GLU A 130 4662 3990 4401 378 -604 -538 C ATOM 852 OE1 GLU A 130 -18.348 14.263 174.971 1.00 36.60 O ANISOU 852 OE1 GLU A 130 4960 4259 4688 393 -587 -535 O ATOM 853 OE2 GLU A 130 -17.638 15.754 176.411 1.00 39.09 O ANISOU 853 OE2 GLU A 130 5310 4568 4974 378 -642 -525 O ATOM 854 N THR A 131 -18.064 15.049 169.639 1.00 25.68 N ANISOU 854 N THR A 131 3341 3019 3397 349 -431 -608 N ATOM 855 CA THR A 131 -17.995 14.144 168.489 1.00 21.84 C ANISOU 855 CA THR A 131 2815 2545 2937 363 -406 -629 C ATOM 856 C THR A 131 -17.724 14.858 167.173 1.00 20.20 C ANISOU 856 C THR A 131 2550 2383 2744 343 -366 -646 C ATOM 857 O THR A 131 -17.193 14.235 166.244 1.00 25.71 O ANISOU 857 O THR A 131 3202 3096 3470 358 -354 -670 O ATOM 858 CB THR A 131 -19.301 13.347 168.324 1.00 21.02 C ANISOU 858 CB THR A 131 2753 2420 2812 364 -378 -617 C ATOM 859 OG1 THR A 131 -20.419 14.254 168.274 1.00 16.92 O ANISOU 859 OG1 THR A 131 2262 1907 2258 334 -342 -597 O ATOM 860 CG2 THR A 131 -19.496 12.358 169.465 1.00 13.92 C ANISOU 860 CG2 THR A 131 1909 1475 1905 388 -414 -603 C ATOM 861 N GLY A 132 -18.094 16.131 167.056 1.00 19.96 N ANISOU 861 N GLY A 132 2524 2370 2691 311 -343 -634 N ATOM 862 CA GLY A 132 -18.040 16.819 165.777 1.00 22.40 C ANISOU 862 CA GLY A 132 2789 2717 3004 290 -300 -646 C ATOM 863 C GLY A 132 -19.261 16.640 164.890 1.00 27.72 C ANISOU 863 C GLY A 132 3478 3396 3657 280 -254 -641 C ATOM 864 O GLY A 132 -19.311 17.237 163.807 1.00 30.49 O ANISOU 864 O GLY A 132 3801 3778 4007 262 -217 -649 O ATOM 865 N LEU A 133 -20.248 15.840 165.316 1.00 26.38 N ANISOU 865 N LEU A 133 3354 3197 3470 290 -254 -628 N ATOM 866 CA LEU A 133 -21.506 15.616 164.616 1.00 17.80 C ANISOU 866 CA LEU A 133 2286 2111 2365 281 -216 -623 C ATOM 867 C LEU A 133 -22.503 16.727 164.945 1.00 13.40 C ANISOU 867 C LEU A 133 1763 1555 1773 254 -197 -598 C ATOM 868 O LEU A 133 -22.431 17.329 166.018 1.00 20.63 O ANISOU 868 O LEU A 133 2707 2455 2675 249 -219 -581 O ATOM 869 CB LEU A 133 -22.098 14.273 165.022 1.00 17.59 C ANISOU 869 CB LEU A 133 2293 2051 2340 301 -227 -620 C ATOM 870 CG LEU A 133 -21.198 13.061 164.828 1.00 19.55 C ANISOU 870 CG LEU A 133 2515 2291 2621 332 -250 -643 C ATOM 871 CD1 LEU A 133 -21.776 11.848 165.532 1.00 21.26 C ANISOU 871 CD1 LEU A 133 2778 2465 2835 351 -267 -633 C ATOM 872 CD2 LEU A 133 -21.032 12.801 163.364 1.00 24.79 C ANISOU 872 CD2 LEU A 133 3136 2984 3300 334 -218 -668 C ATOM 873 N PRO A 134 -23.429 17.025 164.031 1.00 14.23 N ANISOU 873 N PRO A 134 1867 1676 1864 239 -159 -595 N ATOM 874 CA PRO A 134 -24.478 18.003 164.345 1.00 11.65 C ANISOU 874 CA PRO A 134 1574 1347 1507 218 -141 -572 C ATOM 875 C PRO A 134 -25.345 17.512 165.489 1.00 15.03 C ANISOU 875 C PRO A 134 2053 1739 1918 224 -152 -552 C ATOM 876 O PRO A 134 -25.638 16.320 165.603 1.00 16.17 O ANISOU 876 O PRO A 134 2208 1863 2071 239 -157 -555 O ATOM 877 CB PRO A 134 -25.290 18.079 163.050 1.00 13.57 C ANISOU 877 CB PRO A 134 1802 1612 1742 207 -103 -577 C ATOM 878 CG PRO A 134 -24.377 17.578 161.988 1.00 13.70 C ANISOU 878 CG PRO A 134 1773 1651 1783 216 -99 -604 C ATOM 879 CD PRO A 134 -23.510 16.548 162.640 1.00 13.98 C ANISOU 879 CD PRO A 134 1802 1666 1842 241 -132 -616 C ATOM 880 N GLU A 135 -25.810 18.455 166.308 1.00 14.34 N ANISOU 880 N GLU A 135 1999 1642 1806 212 -151 -531 N ATOM 881 CA GLU A 135 -26.660 18.084 167.429 1.00 9.60 C ANISOU 881 CA GLU A 135 1450 1009 1186 216 -155 -511 C ATOM 882 C GLU A 135 -27.928 17.382 166.965 1.00 13.19 C ANISOU 882 C GLU A 135 1914 1459 1639 214 -126 -506 C ATOM 883 O GLU A 135 -28.457 16.531 167.689 1.00 10.23 O ANISOU 883 O GLU A 135 1573 1055 1260 222 -131 -496 O ATOM 884 CB GLU A 135 -27.005 19.321 168.262 1.00 12.36 C ANISOU 884 CB GLU A 135 1834 1354 1508 202 -153 -491 C ATOM 885 CG GLU A 135 -27.946 19.018 169.434 1.00 15.96 C ANISOU 885 CG GLU A 135 2346 1777 1941 206 -151 -469 C ATOM 886 CD GLU A 135 -29.414 19.156 169.078 1.00 23.22 C ANISOU 886 CD GLU A 135 3276 2699 2848 195 -110 -457 C ATOM 887 OE1 GLU A 135 -30.261 18.571 169.796 1.00 22.71 O ANISOU 887 OE1 GLU A 135 3248 2609 2772 198 -101 -443 O ATOM 888 OE2 GLU A 135 -29.694 19.898 168.121 1.00 21.57 O ANISOU 888 OE2 GLU A 135 3040 2517 2639 183 -87 -462 O ATOM 889 N SER A 136 -28.445 17.719 165.773 1.00 8.78 N ANISOU 889 N SER A 136 1329 927 1082 202 -97 -513 N ATOM 890 CA SER A 136 -29.674 17.072 165.327 1.00 12.07 C ANISOU 890 CA SER A 136 1751 1338 1497 199 -73 -510 C ATOM 891 C SER A 136 -29.439 15.596 165.031 1.00 11.78 C ANISOU 891 C SER A 136 1705 1288 1483 214 -85 -526 C ATOM 892 O SER A 136 -30.366 14.783 165.156 1.00 13.56 O ANISOU 892 O SER A 136 1950 1494 1709 213 -75 -520 O ATOM 893 CB SER A 136 -30.229 17.755 164.086 1.00 10.53 C ANISOU 893 CB SER A 136 1529 1174 1297 185 -45 -516 C ATOM 894 OG SER A 136 -29.384 17.507 162.977 1.00 10.83 O ANISOU 894 OG SER A 136 1528 1234 1352 190 -47 -539 O ATOM 895 N ARG A 137 -28.218 15.245 164.627 1.00 8.98 N ANISOU 895 N ARG A 137 1321 942 1147 227 -104 -546 N ATOM 896 CA ARG A 137 -27.875 13.847 164.395 1.00 15.11 C ANISOU 896 CA ARG A 137 2091 1704 1947 245 -117 -563 C ATOM 897 C ARG A 137 -27.714 13.112 165.710 1.00 17.89 C ANISOU 897 C ARG A 137 2482 2016 2299 260 -145 -550 C ATOM 898 O ARG A 137 -28.053 11.928 165.812 1.00 14.41 O ANISOU 898 O ARG A 137 2058 1550 1868 269 -149 -552 O ATOM 899 CB ARG A 137 -26.600 13.755 163.572 1.00 10.63 C ANISOU 899 CB ARG A 137 1478 1159 1400 257 -126 -589 C ATOM 900 CG ARG A 137 -26.670 14.481 162.210 1.00 13.98 C ANISOU 900 CG ARG A 137 1867 1622 1821 243 -97 -602 C ATOM 901 CD ARG A 137 -27.872 13.991 161.376 1.00 14.28 C ANISOU 901 CD ARG A 137 1910 1662 1853 235 -73 -605 C ATOM 902 NE ARG A 137 -29.065 14.819 161.568 1.00 13.67 N ANISOU 902 NE ARG A 137 1854 1587 1753 215 -54 -583 N ATOM 903 CZ ARG A 137 -30.305 14.410 161.311 1.00 14.67 C ANISOU 903 CZ ARG A 137 1994 1706 1875 207 -39 -577 C ATOM 904 NH1 ARG A 137 -30.524 13.165 160.903 1.00 8.84 N ANISOU 904 NH1 ARG A 137 1254 954 1152 215 -42 -592 N ATOM 905 NH2 ARG A 137 -31.334 15.225 161.515 1.00 19.01 N ANISOU 905 NH2 ARG A 137 2558 2259 2406 192 -22 -558 N ATOM 906 N ILE A 138 -27.185 13.802 166.723 1.00 12.17 N ANISOU 906 N ILE A 138 1776 1285 1563 261 -165 -537 N ATOM 907 CA ILE A 138 -27.114 13.225 168.059 1.00 13.08 C ANISOU 907 CA ILE A 138 1936 1362 1671 273 -191 -522 C ATOM 908 C ILE A 138 -28.514 12.868 168.529 1.00 9.56 C ANISOU 908 C ILE A 138 1533 892 1207 262 -168 -500 C ATOM 909 O ILE A 138 -28.760 11.759 169.014 1.00 11.21 O ANISOU 909 O ILE A 138 1770 1069 1421 271 -177 -495 O ATOM 910 CB ILE A 138 -26.426 14.196 169.044 1.00 16.37 C ANISOU 910 CB ILE A 138 2369 1778 2073 273 -216 -511 C ATOM 911 CG1 ILE A 138 -24.898 14.053 169.038 1.00 21.16 C ANISOU 911 CG1 ILE A 138 2945 2392 2704 291 -254 -530 C ATOM 912 CG2 ILE A 138 -26.829 13.837 170.445 1.00 17.92 C ANISOU 912 CG2 ILE A 138 2626 1934 2247 278 -231 -488 C ATOM 913 CD1 ILE A 138 -24.224 14.441 167.812 1.00 29.08 C ANISOU 913 CD1 ILE A 138 3888 3432 3728 288 -243 -553 C ATOM 914 N GLN A 139 -29.455 13.804 168.365 1.00 9.30 N ANISOU 914 N GLN A 139 1503 876 1156 241 -137 -488 N ATOM 915 CA GLN A 139 -30.839 13.589 168.782 1.00 9.24 C ANISOU 915 CA GLN A 139 1528 849 1133 228 -110 -469 C ATOM 916 C GLN A 139 -31.432 12.355 168.110 1.00 12.08 C ANISOU 916 C GLN A 139 1878 1198 1512 228 -99 -478 C ATOM 917 O GLN A 139 -32.042 11.503 168.769 1.00 9.45 O ANISOU 917 O GLN A 139 1580 833 1177 227 -96 -465 O ATOM 918 CB GLN A 139 -31.668 14.834 168.455 1.00 8.97 C ANISOU 918 CB GLN A 139 1485 840 1083 209 -78 -460 C ATOM 919 CG GLN A 139 -33.090 14.807 169.009 1.00 11.57 C ANISOU 919 CG GLN A 139 1846 1153 1397 197 -48 -439 C ATOM 920 CD GLN A 139 -33.638 16.210 169.369 1.00 23.04 C ANISOU 920 CD GLN A 139 3310 2618 2825 186 -28 -424 C ATOM 921 OE1 GLN A 139 -33.289 17.213 168.751 1.00 22.98 O ANISOU 921 OE1 GLN A 139 3277 2639 2816 182 -27 -431 O ATOM 922 NE2 GLN A 139 -34.504 16.266 170.367 1.00 16.48 N ANISOU 922 NE2 GLN A 139 2519 1766 1975 181 -10 -402 N ATOM 923 N ILE A 140 -31.246 12.236 166.792 1.00 10.93 N ANISOU 923 N ILE A 140 1689 1080 1386 228 -92 -501 N ATOM 924 CA ILE A 140 -31.716 11.056 166.061 1.00 12.91 C ANISOU 924 CA ILE A 140 1930 1321 1656 228 -86 -514 C ATOM 925 C ILE A 140 -30.995 9.800 166.538 1.00 11.31 C ANISOU 925 C ILE A 140 1745 1084 1468 249 -115 -520 C ATOM 926 O ILE A 140 -31.591 8.723 166.641 1.00 12.73 O ANISOU 926 O ILE A 140 1945 1235 1656 247 -112 -518 O ATOM 927 CB ILE A 140 -31.527 11.253 164.543 1.00 9.17 C ANISOU 927 CB ILE A 140 1408 883 1193 226 -75 -539 C ATOM 928 CG1 ILE A 140 -32.376 12.426 164.034 1.00 8.90 C ANISOU 928 CG1 ILE A 140 1360 878 1143 206 -48 -531 C ATOM 929 CG2 ILE A 140 -31.834 9.925 163.780 1.00 9.32 C ANISOU 929 CG2 ILE A 140 1419 889 1233 230 -75 -558 C ATOM 930 CD1 ILE A 140 -33.824 12.315 164.418 1.00 16.51 C ANISOU 930 CD1 ILE A 140 2347 1827 2100 190 -26 -513 C ATOM 931 N TRP A 141 -29.699 9.900 166.814 1.00 9.73 N ANISOU 931 N TRP A 141 1537 886 1274 269 -144 -529 N ATOM 932 CA TRP A 141 -28.976 8.715 167.262 1.00 10.06 C ANISOU 932 CA TRP A 141 1595 895 1331 293 -176 -535 C ATOM 933 C TRP A 141 -29.593 8.144 168.530 1.00 14.62 C ANISOU 933 C TRP A 141 2232 1429 1895 291 -181 -508 C ATOM 934 O TRP A 141 -29.732 6.925 168.658 1.00 11.68 O ANISOU 934 O TRP A 141 1880 1023 1534 299 -190 -510 O ATOM 935 CB TRP A 141 -27.512 9.055 167.490 1.00 11.13 C ANISOU 935 CB TRP A 141 1711 1042 1476 314 -209 -547 C ATOM 936 CG TRP A 141 -26.643 7.868 167.718 1.00 11.20 C ANISOU 936 CG TRP A 141 1726 1023 1507 344 -243 -559 C ATOM 937 CD1 TRP A 141 -25.939 7.176 166.780 1.00 10.72 C ANISOU 937 CD1 TRP A 141 1627 970 1474 363 -251 -589 C ATOM 938 CD2 TRP A 141 -26.363 7.251 168.977 1.00 10.88 C ANISOU 938 CD2 TRP A 141 1732 941 1461 360 -276 -543 C ATOM 939 NE1 TRP A 141 -25.225 6.156 167.386 1.00 12.22 N ANISOU 939 NE1 TRP A 141 1837 1127 1680 392 -287 -592 N ATOM 940 CE2 TRP A 141 -25.483 6.183 168.738 1.00 11.92 C ANISOU 940 CE2 TRP A 141 1852 1057 1621 391 -305 -563 C ATOM 941 CE3 TRP A 141 -26.776 7.503 170.293 1.00 17.49 C ANISOU 941 CE3 TRP A 141 2625 1752 2270 354 -284 -513 C ATOM 942 CZ2 TRP A 141 -25.008 5.355 169.766 1.00 16.55 C ANISOU 942 CZ2 TRP A 141 2479 1601 2209 415 -344 -553 C ATOM 943 CZ3 TRP A 141 -26.311 6.674 171.314 1.00 13.87 C ANISOU 943 CZ3 TRP A 141 2209 1251 1810 376 -321 -502 C ATOM 944 CH2 TRP A 141 -25.435 5.615 171.044 1.00 15.22 C ANISOU 944 CH2 TRP A 141 2366 1406 2010 407 -352 -522 C ATOM 945 N PHE A 142 -29.973 9.020 169.474 1.00 12.97 N ANISOU 945 N PHE A 142 2052 1218 1658 279 -174 -484 N ATOM 946 CA PHE A 142 -30.540 8.586 170.744 1.00 10.31 C ANISOU 946 CA PHE A 142 1775 840 1302 276 -175 -457 C ATOM 947 C PHE A 142 -31.952 8.053 170.578 1.00 17.40 C ANISOU 947 C PHE A 142 2687 1724 2199 255 -139 -446 C ATOM 948 O PHE A 142 -32.330 7.093 171.254 1.00 16.14 O ANISOU 948 O PHE A 142 2570 1525 2038 255 -141 -432 O ATOM 949 CB PHE A 142 -30.532 9.738 171.764 1.00 10.24 C ANISOU 949 CB PHE A 142 1795 835 1262 271 -176 -436 C ATOM 950 CG PHE A 142 -29.259 9.825 172.541 1.00 11.16 C ANISOU 950 CG PHE A 142 1927 941 1374 293 -222 -437 C ATOM 951 CD1 PHE A 142 -28.147 10.453 172.004 1.00 13.95 C ANISOU 951 CD1 PHE A 142 2234 1325 1741 303 -244 -458 C ATOM 952 CD2 PHE A 142 -29.153 9.223 173.782 1.00 14.82 C ANISOU 952 CD2 PHE A 142 2449 1363 1820 305 -245 -418 C ATOM 953 CE1 PHE A 142 -26.949 10.498 172.696 1.00 15.94 C ANISOU 953 CE1 PHE A 142 2495 1568 1994 324 -290 -461 C ATOM 954 CE2 PHE A 142 -27.962 9.276 174.492 1.00 18.40 C ANISOU 954 CE2 PHE A 142 2916 1805 2271 328 -293 -420 C ATOM 955 CZ PHE A 142 -26.856 9.904 173.945 1.00 16.85 C ANISOU 955 CZ PHE A 142 2669 1641 2092 337 -317 -442 C ATOM 956 N GLN A 143 -32.761 8.681 169.719 1.00 9.99 N ANISOU 956 N GLN A 143 1716 818 1263 235 -106 -451 N ATOM 957 CA GLN A 143 -34.093 8.144 169.438 1.00 10.44 C ANISOU 957 CA GLN A 143 1776 863 1325 213 -74 -444 C ATOM 958 C GLN A 143 -34.003 6.740 168.850 1.00 14.43 C ANISOU 958 C GLN A 143 2277 1347 1858 219 -85 -461 C ATOM 959 O GLN A 143 -34.684 5.822 169.316 1.00 15.71 O ANISOU 959 O GLN A 143 2472 1474 2023 210 -77 -448 O ATOM 960 CB GLN A 143 -34.863 9.072 168.493 1.00 10.71 C ANISOU 960 CB GLN A 143 1771 938 1361 195 -44 -451 C ATOM 961 CG GLN A 143 -35.032 10.492 169.044 1.00 19.86 C ANISOU 961 CG GLN A 143 2936 2117 2494 189 -31 -435 C ATOM 962 CD GLN A 143 -35.915 11.388 168.186 1.00 19.42 C ANISOU 962 CD GLN A 143 2846 2096 2438 173 -1 -438 C ATOM 963 OE1 GLN A 143 -36.351 11.009 167.105 1.00 21.31 O ANISOU 963 OE1 GLN A 143 3052 2348 2694 165 7 -453 O ATOM 964 NE2 GLN A 143 -36.157 12.593 168.663 1.00 15.25 N ANISOU 964 NE2 GLN A 143 2326 1581 1888 168 12 -424 N ATOM 965 N ASN A 144 -33.153 6.540 167.836 1.00 10.33 N ANISOU 965 N ASN A 144 1719 847 1358 235 -103 -490 N ATOM 966 CA ASN A 144 -32.986 5.202 167.270 1.00 11.37 C ANISOU 966 CA ASN A 144 1849 957 1515 244 -115 -508 C ATOM 967 C ASN A 144 -32.472 4.211 168.320 1.00 14.17 C ANISOU 967 C ASN A 144 2252 1263 1870 262 -143 -497 C ATOM 968 O ASN A 144 -32.980 3.092 168.444 1.00 18.52 O ANISOU 968 O ASN A 144 2828 1776 2431 257 -141 -493 O ATOM 969 CB ASN A 144 -32.037 5.264 166.077 1.00 10.50 C ANISOU 969 CB ASN A 144 1691 877 1421 261 -128 -542 C ATOM 970 CG ASN A 144 -32.744 5.663 164.788 1.00 10.92 C ANISOU 970 CG ASN A 144 1706 966 1479 243 -102 -558 C ATOM 971 OD1 ASN A 144 -33.884 5.273 164.556 1.00 13.18 O ANISOU 971 OD1 ASN A 144 1998 1243 1769 222 -83 -553 O ATOM 972 ND2 ASN A 144 -32.050 6.411 163.925 1.00 10.39 N ANISOU 972 ND2 ASN A 144 1598 938 1412 250 -103 -577 N ATOM 973 N ARG A 145 -31.454 4.603 169.078 1.00 16.93 N ANISOU 973 N ARG A 145 2613 1609 2209 283 -171 -491 N ATOM 974 CA ARG A 145 -30.871 3.670 170.036 1.00 15.20 C ANISOU 974 CA ARG A 145 2440 1345 1991 305 -203 -481 C ATOM 975 C ARG A 145 -31.885 3.255 171.096 1.00 21.46 C ANISOU 975 C ARG A 145 3292 2098 2764 286 -186 -449 C ATOM 976 O ARG A 145 -31.915 2.089 171.512 1.00 22.26 O ANISOU 976 O ARG A 145 3432 2154 2872 294 -199 -442 O ATOM 977 CB ARG A 145 -29.647 4.289 170.698 1.00 21.68 C ANISOU 977 CB ARG A 145 3262 2174 2802 329 -238 -480 C ATOM 978 CG ARG A 145 -28.899 3.312 171.597 1.00 22.39 C ANISOU 978 CG ARG A 145 3395 2217 2894 357 -280 -473 C ATOM 979 CD ARG A 145 -27.737 2.682 170.875 1.00 26.14 C ANISOU 979 CD ARG A 145 3829 2701 3401 387 -309 -501 C ATOM 980 NE ARG A 145 -27.187 1.563 171.621 1.00 27.92 N ANISOU 980 NE ARG A 145 4093 2884 3632 411 -344 -491 N ATOM 981 CZ ARG A 145 -26.302 0.711 171.123 1.00 24.97 C ANISOU 981 CZ ARG A 145 3693 2507 3286 437 -369 -510 C ATOM 982 NH1 ARG A 145 -25.859 -0.298 171.866 1.00 24.97 N ANISOU 982 NH1 ARG A 145 3733 2467 3289 460 -402 -498 N ATOM 983 NH2 ARG A 145 -25.863 0.868 169.881 1.00 24.78 N ANISOU 983 NH2 ARG A 145 3607 2523 3286 442 -359 -540 N ATOM 984 N ARG A 146 -32.731 4.190 171.550 1.00 20.16 N ANISOU 984 N ARG A 146 3137 1948 2575 263 -156 -428 N ATOM 985 CA ARG A 146 -33.732 3.829 172.550 1.00 23.78 C ANISOU 985 CA ARG A 146 3651 2371 3016 243 -133 -397 C ATOM 986 C ARG A 146 -34.734 2.833 171.995 1.00 25.37 C ANISOU 986 C ARG A 146 3850 2552 3237 222 -108 -399 C ATOM 987 O ARG A 146 -35.212 1.954 172.720 1.00 20.92 O ANISOU 987 O ARG A 146 3335 1944 2670 214 -103 -380 O ATOM 988 CB ARG A 146 -34.464 5.065 173.059 1.00 22.60 C ANISOU 988 CB ARG A 146 3507 2243 2838 224 -101 -377 C ATOM 989 CG ARG A 146 -33.619 5.975 173.924 1.00 11.35 C ANISOU 989 CG ARG A 146 2101 824 1385 241 -125 -368 C ATOM 990 CD ARG A 146 -34.504 6.964 174.666 1.00 17.08 C ANISOU 990 CD ARG A 146 2852 1559 2081 221 -89 -345 C ATOM 991 NE ARG A 146 -35.222 7.860 173.770 1.00 18.48 N ANISOU 991 NE ARG A 146 2979 1777 2265 203 -56 -354 N ATOM 992 CZ ARG A 146 -34.837 9.097 173.477 1.00 18.25 C ANISOU 992 CZ ARG A 146 2921 1786 2228 206 -59 -362 C ATOM 993 NH1 ARG A 146 -33.723 9.591 174.005 1.00 12.71 N ANISOU 993 NH1 ARG A 146 2232 1086 1513 225 -93 -364 N ATOM 994 NH2 ARG A 146 -35.567 9.834 172.646 1.00 22.39 N ANISOU 994 NH2 ARG A 146 3404 2344 2760 190 -28 -369 N ATOM 995 N ALA A 147 -35.086 2.967 170.718 1.00 18.12 N ANISOU 995 N ALA A 147 2878 1666 2341 211 -94 -423 N ATOM 996 CA ALA A 147 -36.034 2.053 170.111 1.00 23.30 C ANISOU 996 CA ALA A 147 3528 2305 3019 189 -74 -429 C ATOM 997 C ALA A 147 -35.481 0.645 169.983 1.00 22.98 C ANISOU 997 C ALA A 147 3509 2225 2999 206 -102 -441 C ATOM 998 O ALA A 147 -36.264 -0.310 169.954 1.00 24.95 O ANISOU 998 O ALA A 147 3777 2440 3261 187 -89 -436 O ATOM 999 CB ALA A 147 -36.445 2.573 168.738 1.00 12.69 C ANISOU 999 CB ALA A 147 2124 1007 1691 177 -58 -453 C ATOM 1000 N ARG A 148 -34.160 0.493 169.911 1.00 21.22 N ANISOU 1000 N ARG A 148 3281 2001 2781 241 -141 -457 N ATOM 1001 CA ARG A 148 -33.539 -0.781 169.579 1.00 20.26 C ANISOU 1001 CA ARG A 148 3169 1845 2682 263 -169 -475 C ATOM 1002 C ARG A 148 -32.746 -1.412 170.719 1.00 25.69 C ANISOU 1002 C ARG A 148 3905 2496 3361 286 -201 -455 C ATOM 1003 O ARG A 148 -32.351 -2.577 170.603 1.00 25.97 O ANISOU 1003 O ARG A 148 3949 2505 3414 299 -220 -459 O ATOM 1004 CB ARG A 148 -32.617 -0.601 168.370 1.00 24.89 C ANISOU 1004 CB ARG A 148 3693 2476 3287 282 -182 -508 C ATOM 1005 CG ARG A 148 -33.361 -0.123 167.157 1.00 20.21 C ANISOU 1005 CG ARG A 148 3057 1920 2703 261 -155 -529 C ATOM 1006 CD ARG A 148 -32.447 0.376 166.043 1.00 19.85 C ANISOU 1006 CD ARG A 148 2952 1926 2666 276 -161 -555 C ATOM 1007 NE ARG A 148 -33.184 0.435 164.789 1.00 19.75 N ANISOU 1007 NE ARG A 148 2904 1938 2661 256 -138 -574 N ATOM 1008 CZ ARG A 148 -32.868 1.196 163.745 1.00 20.00 C ANISOU 1008 CZ ARG A 148 2887 2019 2691 257 -129 -592 C ATOM 1009 NH1 ARG A 148 -31.815 2.011 163.777 1.00 14.51 N ANISOU 1009 NH1 ARG A 148 2169 1354 1988 276 -140 -594 N ATOM 1010 NH2 ARG A 148 -33.615 1.144 162.647 1.00 17.15 N ANISOU 1010 NH2 ARG A 148 2503 1677 2336 238 -111 -607 N ATOM 1011 N HIS A 149 -32.512 -0.692 171.808 1.00 22.67 N ANISOU 1011 N HIS A 149 3554 2110 2950 292 -209 -432 N ATOM 1012 CA HIS A 149 -31.729 -1.198 172.918 1.00 24.71 C ANISOU 1012 CA HIS A 149 3858 2335 3196 316 -243 -412 C ATOM 1013 C HIS A 149 -32.320 -0.660 174.211 1.00 47.21 C ANISOU 1013 C HIS A 149 6766 5163 6007 302 -229 -378 C ATOM 1014 O HIS A 149 -33.544 -0.494 174.314 1.00 47.61 O ANISOU 1014 O HIS A 149 6832 5210 6049 268 -187 -363 O ATOM 1015 CB HIS A 149 -30.256 -0.800 172.785 1.00 23.33 C ANISOU 1015 CB HIS A 149 3649 2187 3027 352 -284 -429 C ATOM 1016 CG HIS A 149 -29.572 -1.372 171.577 1.00 26.83 C ANISOU 1016 CG HIS A 149 4039 2651 3506 370 -296 -462 C ATOM 1017 ND1 HIS A 149 -28.887 -2.569 171.603 1.00 33.97 N ANISOU 1017 ND1 HIS A 149 4953 3527 4427 394 -325 -466 N ATOM 1018 CD2 HIS A 149 -29.450 -0.899 170.313 1.00 30.22 C ANISOU 1018 CD2 HIS A 149 4405 3125 3952 366 -281 -491 C ATOM 1019 CE1 HIS A 149 -28.385 -2.816 170.404 1.00 33.27 C ANISOU 1019 CE1 HIS A 149 4810 3465 4366 406 -326 -497 C ATOM 1020 NE2 HIS A 149 -28.715 -1.820 169.601 1.00 31.34 N ANISOU 1020 NE2 HIS A 149 4521 3265 4121 388 -299 -512 N ATOM 1021 OXT HIS A 149 -31.598 -0.388 175.177 1.00 65.09 O ANISOU 1021 OXT HIS A 149 9062 7418 8249 322 -258 -363 O TER 1022 HIS A 149 ATOM 1023 O5' DC D 1 -56.896 28.530 186.419 1.00 57.89 O ANISOU 1023 O5' DC D 1 8137 6914 6942 245 964 -126 O ATOM 1024 C5' DC D 1 -58.197 29.122 186.410 1.00 50.98 C ANISOU 1024 C5' DC D 1 7216 6058 6097 258 1010 -129 C ATOM 1025 C4' DC D 1 -58.717 29.244 184.987 1.00 43.36 C ANISOU 1025 C4' DC D 1 6164 5126 5184 262 1002 -144 C ATOM 1026 O4' DC D 1 -58.025 30.324 184.294 1.00 40.74 O ANISOU 1026 O4' DC D 1 5826 4805 4847 281 945 -156 O ATOM 1027 C3' DC D 1 -58.526 27.996 184.131 1.00 43.55 C ANISOU 1027 C3' DC D 1 6155 5156 5236 239 996 -148 C ATOM 1028 O3' DC D 1 -59.724 27.689 183.459 1.00 48.69 O ANISOU 1028 O3' DC D 1 6728 5830 5940 235 1034 -154 O ATOM 1029 C2' DC D 1 -57.419 28.390 183.154 1.00 37.83 C ANISOU 1029 C2' DC D 1 5426 4440 4508 245 926 -161 C ATOM 1030 C1' DC D 1 -57.638 29.885 183.014 1.00 37.12 C ANISOU 1030 C1' DC D 1 5323 4364 4417 273 911 -167 C ATOM 1031 N1 DC D 1 -56.401 30.623 182.607 1.00 25.26 N ANISOU 1031 N1 DC D 1 3846 2860 2892 281 845 -174 N ATOM 1032 C2 DC D 1 -56.363 31.305 181.377 1.00 20.91 C ANISOU 1032 C2 DC D 1 3245 2332 2366 293 812 -188 C ATOM 1033 O2 DC D 1 -57.367 31.294 180.630 1.00 22.21 O ANISOU 1033 O2 DC D 1 3347 2519 2573 300 835 -195 O ATOM 1034 N3 DC D 1 -55.222 31.949 181.022 1.00 19.05 N ANISOU 1034 N3 DC D 1 3032 2094 2111 297 756 -192 N ATOM 1035 C4 DC D 1 -54.168 31.942 181.839 1.00 19.80 C ANISOU 1035 C4 DC D 1 3191 2166 2165 289 731 -185 C ATOM 1036 N4 DC D 1 -53.076 32.602 181.445 1.00 24.54 N ANISOU 1036 N4 DC D 1 3806 2767 2751 291 676 -190 N ATOM 1037 C5 DC D 1 -54.189 31.263 183.093 1.00 19.23 C ANISOU 1037 C5 DC D 1 3170 2070 2065 279 760 -171 C ATOM 1038 C6 DC D 1 -55.311 30.615 183.432 1.00 16.76 C ANISOU 1038 C6 DC D 1 2839 1758 1770 275 818 -166 C ATOM 1039 P DC D 2 -59.917 26.245 182.791 1.00 52.16 P ANISOU 1039 P DC D 2 7129 6273 6416 206 1050 -156 P ATOM 1040 OP1 DC D 2 -61.372 25.971 182.754 1.00 57.49 O ANISOU 1040 OP1 DC D 2 7741 6965 7139 198 1109 -155 O ATOM 1041 OP2 DC D 2 -58.960 25.312 183.433 1.00 50.57 O ANISOU 1041 OP2 DC D 2 6998 6041 6176 186 1041 -146 O ATOM 1042 O5' DC D 2 -59.440 26.456 181.282 1.00 52.37 O ANISOU 1042 O5' DC D 2 7105 6322 6470 213 996 -176 O ATOM 1043 C5' DC D 2 -60.108 27.409 180.467 1.00 46.26 C ANISOU 1043 C5' DC D 2 6270 5577 5729 235 987 -188 C ATOM 1044 C4' DC D 2 -59.392 27.560 179.149 1.00 42.05 C ANISOU 1044 C4' DC D 2 5709 5058 5209 241 930 -204 C ATOM 1045 O4' DC D 2 -58.187 28.354 179.328 1.00 36.62 O ANISOU 1045 O4' DC D 2 5078 4360 4476 253 879 -204 O ATOM 1046 C3' DC D 2 -58.938 26.242 178.528 1.00 40.87 C ANISOU 1046 C3' DC D 2 5547 4904 5076 213 918 -210 C ATOM 1047 O3' DC D 2 -59.268 26.238 177.168 1.00 46.19 O ANISOU 1047 O3' DC D 2 6145 5606 5797 212 883 -222 O ATOM 1048 C2' DC D 2 -57.426 26.260 178.729 1.00 38.38 C ANISOU 1048 C2' DC D 2 5299 4570 4713 212 868 -209 C ATOM 1049 C1' DC D 2 -57.145 27.744 178.619 1.00 33.25 C ANISOU 1049 C1' DC D 2 4658 3929 4044 240 836 -212 C ATOM 1050 N1 DC D 2 -55.850 28.139 179.215 1.00 27.77 N ANISOU 1050 N1 DC D 2 4034 3216 3300 243 794 -206 N ATOM 1051 C2 DC D 2 -55.026 29.033 178.535 1.00 17.54 C ANISOU 1051 C2 DC D 2 2739 1931 1996 255 740 -215 C ATOM 1052 O2 DC D 2 -55.413 29.507 177.465 1.00 21.99 O ANISOU 1052 O2 DC D 2 3250 2516 2588 266 728 -226 O ATOM 1053 N3 DC D 2 -53.836 29.375 179.085 1.00 19.91 N ANISOU 1053 N3 DC D 2 3097 2214 2255 254 702 -210 N ATOM 1054 C4 DC D 2 -53.459 28.841 180.246 1.00 21.57 C ANISOU 1054 C4 DC D 2 3364 2399 2433 244 713 -198 C ATOM 1055 N4 DC D 2 -52.273 29.208 180.752 1.00 21.13 N ANISOU 1055 N4 DC D 2 3360 2328 2341 244 671 -194 N ATOM 1056 C5 DC D 2 -54.285 27.917 180.946 1.00 22.48 C ANISOU 1056 C5 DC D 2 3486 2503 2554 233 769 -188 C ATOM 1057 C6 DC D 2 -55.457 27.594 180.393 1.00 24.26 C ANISOU 1057 C6 DC D 2 3651 2745 2821 231 809 -193 C ATOM 1058 P DA D 3 -59.462 24.854 176.383 1.00 48.58 P ANISOU 1058 P DA D 3 6397 5917 6145 176 863 -223 P ATOM 1059 OP1 DA D 3 -60.917 24.559 176.398 1.00 54.22 O ANISOU 1059 OP1 DA D 3 7049 6645 6907 168 914 -222 O ATOM 1060 OP2 DA D 3 -58.498 23.861 176.907 1.00 46.76 O ANISOU 1060 OP2 DA D 3 6222 5660 5886 152 848 -215 O ATOM 1061 O5' DA D 3 -59.034 25.243 174.903 1.00 49.15 O ANISOU 1061 O5' DA D 3 6426 6012 6234 185 798 -239 O ATOM 1062 C5' DA D 3 -59.480 26.478 174.366 1.00 48.47 C ANISOU 1062 C5' DA D 3 6312 5948 6159 216 792 -248 C ATOM 1063 C4' DA D 3 -58.597 26.924 173.218 1.00 43.94 C ANISOU 1063 C4' DA D 3 5732 5386 5577 224 726 -259 C ATOM 1064 O4' DA D 3 -57.382 27.519 173.734 1.00 43.04 O ANISOU 1064 O4' DA D 3 5689 5254 5411 235 707 -256 O ATOM 1065 C3' DA D 3 -58.166 25.820 172.259 1.00 36.81 C ANISOU 1065 C3' DA D 3 4800 4490 4696 196 682 -266 C ATOM 1066 O3' DA D 3 -58.164 26.332 170.935 1.00 37.27 O ANISOU 1066 O3' DA D 3 4817 4572 4771 208 639 -278 O ATOM 1067 C2' DA D 3 -56.764 25.463 172.744 1.00 35.05 C ANISOU 1067 C2' DA D 3 4643 4244 4430 186 659 -262 C ATOM 1068 C1' DA D 3 -56.253 26.794 173.291 1.00 32.65 C ANISOU 1068 C1' DA D 3 4389 3933 4084 215 660 -259 C ATOM 1069 N9 DA D 3 -55.339 26.643 174.427 1.00 24.67 N ANISOU 1069 N9 DA D 3 3452 2894 3029 211 666 -250 N ATOM 1070 C8 DA D 3 -55.488 25.812 175.511 1.00 26.36 C ANISOU 1070 C8 DA D 3 3697 3085 3231 195 702 -238 C ATOM 1071 N7 DA D 3 -54.505 25.897 176.387 1.00 17.10 N ANISOU 1071 N7 DA D 3 2595 1890 2013 197 693 -232 N ATOM 1072 C5 DA D 3 -53.663 26.842 175.839 1.00 14.23 C ANISOU 1072 C5 DA D 3 2241 1533 1632 213 651 -241 C ATOM 1073 C6 DA D 3 -52.444 27.380 176.271 1.00 18.02 C ANISOU 1073 C6 DA D 3 2779 1997 2069 221 620 -242 C ATOM 1074 N6 DA D 3 -51.849 27.026 177.415 1.00 15.52 N ANISOU 1074 N6 DA D 3 2526 1654 1717 216 626 -233 N ATOM 1075 N1 DA D 3 -51.855 28.305 175.481 1.00 20.91 N ANISOU 1075 N1 DA D 3 3136 2377 2432 233 583 -252 N ATOM 1076 C2 DA D 3 -52.466 28.667 174.346 1.00 18.37 C ANISOU 1076 C2 DA D 3 2756 2081 2143 240 575 -260 C ATOM 1077 N3 DA D 3 -53.613 28.229 173.832 1.00 22.36 N ANISOU 1077 N3 DA D 3 3204 2603 2689 236 597 -261 N ATOM 1078 C4 DA D 3 -54.167 27.316 174.633 1.00 13.27 C ANISOU 1078 C4 DA D 3 2059 1439 1544 222 635 -252 C ATOM 1079 P DC D 4 -57.742 25.416 169.685 1.00 37.47 P ANISOU 1079 P DC D 4 4810 4611 4818 185 588 -290 P ATOM 1080 OP1 DC D 4 -58.472 26.014 168.546 1.00 45.86 O ANISOU 1080 OP1 DC D 4 5814 5700 5910 200 567 -300 O ATOM 1081 OP2 DC D 4 -57.852 23.968 169.950 1.00 30.11 O ANISOU 1081 OP2 DC D 4 3870 3666 3904 152 598 -287 O ATOM 1082 O5' DC D 4 -56.175 25.744 169.525 1.00 31.75 O ANISOU 1082 O5' DC D 4 4137 3877 4049 190 546 -292 O ATOM 1083 C5' DC D 4 -55.780 27.090 169.307 1.00 22.41 C ANISOU 1083 C5' DC D 4 2974 2699 2841 216 531 -293 C ATOM 1084 C4' DC D 4 -54.274 27.209 169.243 1.00 24.42 C ANISOU 1084 C4' DC D 4 3276 2944 3059 213 495 -295 C ATOM 1085 O4' DC D 4 -53.710 27.016 170.569 1.00 19.45 O ANISOU 1085 O4' DC D 4 2704 2288 2399 209 516 -285 O ATOM 1086 C3' DC D 4 -53.574 26.190 168.324 1.00 21.00 C ANISOU 1086 C3' DC D 4 2825 2517 2636 191 455 -305 C ATOM 1087 O3' DC D 4 -52.657 26.876 167.499 1.00 18.49 O ANISOU 1087 O3' DC D 4 2515 2209 2299 200 415 -312 O ATOM 1088 C2' DC D 4 -52.860 25.258 169.310 1.00 14.85 C ANISOU 1088 C2' DC D 4 2088 1713 1840 174 463 -299 C ATOM 1089 C1' DC D 4 -52.558 26.223 170.455 1.00 19.25 C ANISOU 1089 C1' DC D 4 2700 2254 2361 192 484 -288 C ATOM 1090 N1 DC D 4 -52.317 25.572 171.769 1.00 17.25 N ANISOU 1090 N1 DC D 4 2492 1973 2088 182 509 -277 N ATOM 1091 C2 DC D 4 -51.260 26.015 172.571 1.00 12.66 C ANISOU 1091 C2 DC D 4 1971 1372 1465 189 498 -273 C ATOM 1092 O2 DC D 4 -50.533 26.932 172.162 1.00 13.15 O ANISOU 1092 O2 DC D 4 2045 1441 1511 200 470 -279 O ATOM 1093 N3 DC D 4 -51.064 25.428 173.782 1.00 12.95 N ANISOU 1093 N3 DC D 4 2056 1384 1483 181 519 -262 N ATOM 1094 C4 DC D 4 -51.870 24.438 174.180 1.00 14.23 C ANISOU 1094 C4 DC D 4 2206 1537 1663 166 551 -255 C ATOM 1095 N4 DC D 4 -51.633 23.882 175.378 1.00 13.91 N ANISOU 1095 N4 DC D 4 2218 1470 1599 159 571 -242 N ATOM 1096 C5 DC D 4 -52.967 23.987 173.380 1.00 18.07 C ANISOU 1096 C5 DC D 4 2628 2043 2195 157 565 -259 C ATOM 1097 C6 DC D 4 -53.156 24.579 172.201 1.00 14.03 C ANISOU 1097 C6 DC D 4 2070 1558 1703 166 541 -271 C ATOM 1098 P DT D 5 -51.881 26.097 166.327 1.00 20.48 P ANISOU 1098 P DT D 5 2749 2473 2559 184 372 -325 P ATOM 1099 OP1 DT D 5 -51.637 27.096 165.270 1.00 19.99 O ANISOU 1099 OP1 DT D 5 2677 2431 2489 198 345 -331 O ATOM 1100 OP2 DT D 5 -52.526 24.795 166.033 1.00 18.00 O ANISOU 1100 OP2 DT D 5 2398 2161 2278 164 375 -331 O ATOM 1101 O5' DT D 5 -50.485 25.747 167.019 1.00 22.33 O ANISOU 1101 O5' DT D 5 3033 2688 2764 175 361 -323 O ATOM 1102 C5' DT D 5 -49.591 26.790 167.386 1.00 16.52 C ANISOU 1102 C5' DT D 5 2338 1945 1995 188 352 -320 C ATOM 1103 C4' DT D 5 -48.325 26.183 167.941 1.00 10.25 C ANISOU 1103 C4' DT D 5 1580 1133 1182 177 336 -320 C ATOM 1104 O4' DT D 5 -48.626 25.601 169.244 1.00 10.86 O ANISOU 1104 O4' DT D 5 1686 1187 1254 172 364 -309 O ATOM 1105 C3' DT D 5 -47.762 25.036 167.094 1.00 9.00 C ANISOU 1105 C3' DT D 5 1397 982 1039 161 308 -333 C ATOM 1106 O3' DT D 5 -46.354 25.091 167.170 1.00 15.92 O ANISOU 1106 O3' DT D 5 2302 1853 1896 160 281 -337 O ATOM 1107 C2' DT D 5 -48.293 23.801 167.837 1.00 12.42 C ANISOU 1107 C2' DT D 5 1834 1398 1488 148 329 -327 C ATOM 1108 C1' DT D 5 -48.164 24.310 169.274 1.00 9.87 C ANISOU 1108 C1' DT D 5 1561 1052 1137 156 352 -313 C ATOM 1109 N1 DT D 5 -48.905 23.551 170.317 1.00 12.37 N ANISOU 1109 N1 DT D 5 1893 1349 1460 148 387 -301 N ATOM 1110 C2 DT D 5 -48.383 23.534 171.586 1.00 10.90 C ANISOU 1110 C2 DT D 5 1762 1137 1244 151 396 -290 C ATOM 1111 O2 DT D 5 -47.368 24.128 171.876 1.00 12.52 O ANISOU 1111 O2 DT D 5 1999 1336 1421 159 375 -291 O ATOM 1112 N3 DT D 5 -49.103 22.808 172.504 1.00 13.26 N ANISOU 1112 N3 DT D 5 2076 1417 1547 142 431 -278 N ATOM 1113 C4 DT D 5 -50.273 22.111 172.264 1.00 15.39 C ANISOU 1113 C4 DT D 5 2307 1692 1850 129 459 -277 C ATOM 1114 O4 DT D 5 -50.854 21.476 173.136 1.00 17.24 O ANISOU 1114 O4 DT D 5 2558 1907 2085 119 493 -265 O ATOM 1115 C5 DT D 5 -50.761 22.173 170.910 1.00 18.33 C ANISOU 1115 C5 DT D 5 2618 2091 2254 127 443 -290 C ATOM 1116 C7 DT D 5 -52.025 21.444 170.537 1.00 24.25 C ANISOU 1116 C7 DT D 5 3321 2850 3045 112 466 -291 C ATOM 1117 C6 DT D 5 -50.061 22.886 170.011 1.00 13.95 C ANISOU 1117 C6 DT D 5 2053 1555 1692 138 408 -301 C ATOM 1118 P DA D 6 -45.432 25.157 165.857 1.00 10.47 P ANISOU 1118 P DA D 6 1590 1182 1206 156 246 -352 P ATOM 1119 OP1 DA D 6 -45.659 26.444 165.155 1.00 11.76 O ANISOU 1119 OP1 DA D 6 1743 1363 1361 167 244 -352 O ATOM 1120 OP2 DA D 6 -45.556 23.868 165.139 1.00 10.65 O ANISOU 1120 OP2 DA D 6 1582 1211 1253 144 236 -364 O ATOM 1121 O5' DA D 6 -43.968 25.208 166.475 1.00 13.46 O ANISOU 1121 O5' DA D 6 2005 1547 1564 155 227 -353 O ATOM 1122 C5' DA D 6 -43.572 26.319 167.262 1.00 15.86 C ANISOU 1122 C5' DA D 6 2344 1840 1841 163 230 -344 C ATOM 1123 C4' DA D 6 -42.502 25.915 168.261 1.00 10.65 C ANISOU 1123 C4' DA D 6 1721 1159 1167 160 216 -342 C ATOM 1124 O4' DA D 6 -43.074 25.095 169.314 1.00 10.02 O ANISOU 1124 O4' DA D 6 1662 1057 1087 159 236 -333 O ATOM 1125 C3' DA D 6 -41.347 25.103 167.712 1.00 7.94 C ANISOU 1125 C3' DA D 6 1364 821 832 153 186 -356 C ATOM 1126 O3' DA D 6 -40.211 25.385 168.497 1.00 13.75 O ANISOU 1126 O3' DA D 6 2133 1542 1549 154 167 -355 O ATOM 1127 C2' DA D 6 -41.825 23.666 167.912 1.00 8.05 C ANISOU 1127 C2' DA D 6 1371 824 865 147 193 -356 C ATOM 1128 C1' DA D 6 -42.589 23.767 169.223 1.00 8.47 C ANISOU 1128 C1' DA D 6 1458 854 904 151 220 -339 C ATOM 1129 N9 DA D 6 -43.759 22.898 169.336 1.00 8.39 N ANISOU 1129 N9 DA D 6 1435 839 914 145 246 -334 N ATOM 1130 C8 DA D 6 -44.658 22.569 168.370 1.00 8.39 C ANISOU 1130 C8 DA D 6 1392 857 940 139 255 -340 C ATOM 1131 N7 DA D 6 -45.647 21.796 168.810 1.00 8.60 N ANISOU 1131 N7 DA D 6 1415 871 981 132 280 -333 N ATOM 1132 C5 DA D 6 -45.368 21.628 170.150 1.00 13.43 C ANISOU 1132 C5 DA D 6 2075 1456 1573 133 291 -320 C ATOM 1133 C6 DA D 6 -46.044 20.950 171.186 1.00 9.00 C ANISOU 1133 C6 DA D 6 1538 872 1011 126 321 -306 C ATOM 1134 N6 DA D 6 -47.168 20.256 170.999 1.00 9.18 N ANISOU 1134 N6 DA D 6 1533 895 1061 114 346 -303 N ATOM 1135 N1 DA D 6 -45.497 20.984 172.415 1.00 12.72 N ANISOU 1135 N1 DA D 6 2063 1318 1453 131 322 -295 N ATOM 1136 C2 DA D 6 -44.375 21.681 172.600 1.00 10.57 C ANISOU 1136 C2 DA D 6 1815 1045 1156 141 294 -298 C ATOM 1137 N3 DA D 6 -43.653 22.372 171.708 1.00 9.80 N ANISOU 1137 N3 DA D 6 1696 969 1060 147 266 -311 N ATOM 1138 C4 DA D 6 -44.214 22.304 170.494 1.00 12.99 C ANISOU 1138 C4 DA D 6 2049 1397 1491 142 268 -321 C ATOM 1139 P DA D 7 -38.809 24.654 168.251 1.00 12.66 P ANISOU 1139 P DA D 7 1987 1404 1419 150 133 -368 P ATOM 1140 OP1 DA D 7 -37.778 25.543 168.788 1.00 14.01 O ANISOU 1140 OP1 DA D 7 2183 1569 1571 151 115 -367 O ATOM 1141 OP2 DA D 7 -38.708 24.129 166.878 1.00 14.39 O ANISOU 1141 OP2 DA D 7 2162 1646 1659 145 126 -382 O ATOM 1142 O5' DA D 7 -38.875 23.404 169.221 1.00 11.58 O ANISOU 1142 O5' DA D 7 1874 1242 1285 151 133 -362 O ATOM 1143 C5' DA D 7 -38.786 23.617 170.621 1.00 12.67 C ANISOU 1143 C5' DA D 7 2061 1355 1400 156 135 -349 C ATOM 1144 C4' DA D 7 -38.905 22.309 171.361 1.00 11.85 C ANISOU 1144 C4' DA D 7 1977 1227 1300 156 135 -344 C ATOM 1145 O4' DA D 7 -40.210 21.757 171.146 1.00 10.50 O ANISOU 1145 O4' DA D 7 1790 1055 1143 150 167 -338 O ATOM 1146 C3' DA D 7 -37.898 21.229 170.930 1.00 13.74 C ANISOU 1146 C3' DA D 7 2199 1464 1557 156 103 -357 C ATOM 1147 O3' DA D 7 -37.126 20.861 172.048 1.00 17.93 O ANISOU 1147 O3' DA D 7 2771 1969 2073 162 81 -351 O ATOM 1148 C2' DA D 7 -38.777 20.069 170.425 1.00 11.72 C ANISOU 1148 C2' DA D 7 1921 1207 1325 150 120 -359 C ATOM 1149 C1' DA D 7 -40.116 20.360 171.101 1.00 9.31 C ANISOU 1149 C1' DA D 7 1635 892 1009 146 159 -341 C ATOM 1150 N9 DA D 7 -41.283 19.876 170.367 1.00 10.93 N ANISOU 1150 N9 DA D 7 1806 1109 1239 137 183 -343 N ATOM 1151 C8 DA D 7 -41.565 20.090 169.049 1.00 8.71 C ANISOU 1151 C8 DA D 7 1478 855 977 134 182 -356 C ATOM 1152 N7 DA D 7 -42.708 19.570 168.657 1.00 9.90 N ANISOU 1152 N7 DA D 7 1605 1009 1147 125 204 -355 N ATOM 1153 C5 DA D 7 -43.230 19.003 169.815 1.00 9.22 C ANISOU 1153 C5 DA D 7 1551 895 1056 121 225 -339 C ATOM 1154 C6 DA D 7 -44.425 18.298 170.072 1.00 12.05 C ANISOU 1154 C6 DA D 7 1904 1243 1431 109 255 -331 C ATOM 1155 N6 DA D 7 -45.349 18.041 169.135 1.00 13.34 N ANISOU 1155 N6 DA D 7 2023 1424 1622 100 265 -338 N ATOM 1156 N1 DA D 7 -44.638 17.862 171.333 1.00 14.47 N ANISOU 1156 N1 DA D 7 2254 1521 1724 107 274 -314 N ATOM 1157 C2 DA D 7 -43.711 18.126 172.271 1.00 10.07 C ANISOU 1157 C2 DA D 7 1744 946 1137 117 259 -307 C ATOM 1158 N3 DA D 7 -42.554 18.781 172.149 1.00 9.13 N ANISOU 1158 N3 DA D 7 1632 835 1002 129 227 -315 N ATOM 1159 C4 DA D 7 -42.368 19.189 170.880 1.00 9.94 C ANISOU 1159 C4 DA D 7 1689 967 1121 129 213 -331 C ATOM 1160 P DC D 8 -35.979 19.740 171.939 1.00 14.63 P ANISOU 1160 P DC D 8 2347 1543 1671 168 44 -363 P ATOM 1161 OP1 DC D 8 -35.002 20.000 173.015 1.00 18.43 O ANISOU 1161 OP1 DC D 8 2867 2004 2131 176 14 -359 O ATOM 1162 OP2 DC D 8 -35.545 19.635 170.541 1.00 12.22 O ANISOU 1162 OP2 DC D 8 1988 1265 1391 166 35 -383 O ATOM 1163 O5' DC D 8 -36.722 18.396 172.265 1.00 11.58 O ANISOU 1163 O5' DC D 8 1974 1133 1294 166 58 -355 O ATOM 1164 C5' DC D 8 -37.392 18.255 173.475 1.00 18.34 C ANISOU 1164 C5' DC D 8 2879 1961 2128 165 78 -335 C ATOM 1165 C4' DC D 8 -38.255 17.017 173.446 1.00 12.23 C ANISOU 1165 C4' DC D 8 2105 1171 1370 157 98 -329 C ATOM 1166 O4' DC D 8 -39.338 17.207 172.516 1.00 18.97 O ANISOU 1166 O4' DC D 8 2917 2048 2244 146 129 -333 O ATOM 1167 C3' DC D 8 -37.546 15.720 173.022 1.00 16.53 C ANISOU 1167 C3' DC D 8 2637 1705 1938 161 69 -341 C ATOM 1168 O3' DC D 8 -37.490 14.808 174.152 1.00 22.39 O ANISOU 1168 O3' DC D 8 3431 2409 2668 165 63 -326 O ATOM 1169 C2' DC D 8 -38.439 15.164 171.902 1.00 18.20 C ANISOU 1169 C2' DC D 8 2804 1931 2179 149 91 -350 C ATOM 1170 C1' DC D 8 -39.742 15.941 172.110 1.00 19.36 C ANISOU 1170 C1' DC D 8 2952 2087 2317 138 133 -336 C ATOM 1171 N1 DC D 8 -40.601 16.030 170.874 1.00 16.62 N ANISOU 1171 N1 DC D 8 2552 1767 1995 128 151 -347 N ATOM 1172 C2 DC D 8 -41.893 15.519 170.924 1.00 19.67 C ANISOU 1172 C2 DC D 8 2932 2146 2395 113 184 -339 C ATOM 1173 O2 DC D 8 -42.312 15.040 171.992 1.00 15.72 O ANISOU 1173 O2 DC D 8 2471 1617 1884 109 203 -321 O ATOM 1174 N3 DC D 8 -42.657 15.549 169.807 1.00 17.41 N ANISOU 1174 N3 DC D 8 2598 1883 2132 104 195 -350 N ATOM 1175 C4 DC D 8 -42.187 16.082 168.675 1.00 15.01 C ANISOU 1175 C4 DC D 8 2258 1609 1835 110 176 -367 C ATOM 1176 N4 DC D 8 -43.002 16.085 167.614 1.00 11.57 N ANISOU 1176 N4 DC D 8 1780 1195 1419 101 185 -377 N ATOM 1177 C5 DC D 8 -40.865 16.614 168.586 1.00 14.09 C ANISOU 1177 C5 DC D 8 2149 1502 1705 123 147 -376 C ATOM 1178 C6 DC D 8 -40.101 16.561 169.702 1.00 10.57 C ANISOU 1178 C6 DC D 8 1745 1032 1239 132 135 -366 C ATOM 1179 P DC D 9 -36.703 13.407 174.082 1.00 29.44 P ANISOU 1179 P DC D 9 4330 3278 3579 174 30 -333 P ATOM 1180 OP1 DC D 9 -36.144 13.249 175.434 1.00 35.67 O ANISOU 1180 OP1 DC D 9 5179 4034 4339 185 9 -318 O ATOM 1181 OP2 DC D 9 -35.851 13.323 172.893 1.00 30.90 O ANISOU 1181 OP2 DC D 9 4463 3488 3790 181 3 -359 O ATOM 1182 O5' DC D 9 -37.840 12.325 173.795 1.00 28.03 O ANISOU 1182 O5' DC D 9 4146 3085 3421 158 60 -328 O ATOM 1183 C5' DC D 9 -38.895 12.121 174.732 1.00 28.86 C ANISOU 1183 C5' DC D 9 4291 3166 3510 145 96 -304 C ATOM 1184 C4' DC D 9 -40.040 11.338 174.102 1.00 23.28 C ANISOU 1184 C4' DC D 9 3557 2458 2831 125 127 -305 C ATOM 1185 O4' DC D 9 -40.622 12.114 173.061 1.00 20.00 O ANISOU 1185 O4' DC D 9 3087 2080 2431 117 144 -318 O ATOM 1186 C3' DC D 9 -39.640 10.063 173.387 1.00 19.38 C ANISOU 1186 C3' DC D 9 3046 1951 2367 125 102 -320 C ATOM 1187 O3' DC D 9 -39.598 8.977 174.293 1.00 33.87 O ANISOU 1187 O3' DC D 9 4932 3740 4195 125 98 -304 O ATOM 1188 C2' DC D 9 -40.770 9.866 172.371 1.00 18.67 C ANISOU 1188 C2' DC D 9 2910 1880 2306 105 131 -329 C ATOM 1189 C1' DC D 9 -41.362 11.246 172.221 1.00 23.18 C ANISOU 1189 C1' DC D 9 3457 2485 2867 101 156 -326 C ATOM 1190 N1 DC D 9 -41.288 11.754 170.854 1.00 17.09 N ANISOU 1190 N1 DC D 9 2629 1752 2114 103 147 -349 N ATOM 1191 C2 DC D 9 -42.332 11.499 169.983 1.00 15.94 C ANISOU 1191 C2 DC D 9 2444 1620 1994 86 167 -357 C ATOM 1192 O2 DC D 9 -43.284 10.799 170.375 1.00 19.58 O ANISOU 1192 O2 DC D 9 2915 2060 2466 68 192 -345 O ATOM 1193 N3 DC D 9 -42.268 11.995 168.725 1.00 16.09 N ANISOU 1193 N3 DC D 9 2415 1674 2025 88 157 -377 N ATOM 1194 C4 DC D 9 -41.200 12.717 168.350 1.00 15.48 C ANISOU 1194 C4 DC D 9 2330 1617 1936 104 133 -388 C ATOM 1195 N4 DC D 9 -41.175 13.196 167.106 1.00 14.52 N ANISOU 1195 N4 DC D 9 2165 1529 1824 105 126 -407 N ATOM 1196 C5 DC D 9 -40.125 12.990 169.241 1.00 10.06 C ANISOU 1196 C5 DC D 9 1679 918 1227 120 114 -381 C ATOM 1197 C6 DC D 9 -40.213 12.496 170.472 1.00 18.90 C ANISOU 1197 C6 DC D 9 2846 2003 2334 119 120 -362 C ATOM 1198 P DT D 10 -39.038 7.556 173.793 1.00 36.31 P ANISOU 1198 P DT D 10 5239 4025 4530 131 68 -318 P ATOM 1199 OP1 DT D 10 -38.652 6.868 175.033 1.00 42.20 O ANISOU 1199 OP1 DT D 10 6052 4726 5255 139 54 -298 O ATOM 1200 OP2 DT D 10 -38.086 7.727 172.648 1.00 29.08 O ANISOU 1200 OP2 DT D 10 4276 3140 3635 147 35 -348 O ATOM 1201 O5' DT D 10 -40.320 6.849 173.152 1.00 39.30 O ANISOU 1201 O5' DT D 10 5593 4401 4939 103 102 -320 O ATOM 1202 C5' DT D 10 -41.559 6.816 173.835 1.00 27.28 C ANISOU 1202 C5' DT D 10 4092 2864 3410 79 147 -296 C ATOM 1203 C4' DT D 10 -42.606 6.138 172.958 1.00 24.02 C ANISOU 1203 C4' DT D 10 3640 2454 3033 53 169 -305 C ATOM 1204 O4' DT D 10 -42.892 6.963 171.794 1.00 21.10 O ANISOU 1204 O4' DT D 10 3208 2132 2679 51 172 -326 O ATOM 1205 C3' DT D 10 -42.207 4.773 172.410 1.00 27.01 C ANISOU 1205 C3' DT D 10 4020 2806 3438 53 141 -320 C ATOM 1206 O3' DT D 10 -43.317 3.898 172.476 1.00 32.44 O ANISOU 1206 O3' DT D 10 4712 3468 4145 22 171 -310 O ATOM 1207 C2' DT D 10 -41.824 5.068 170.961 1.00 23.20 C ANISOU 1207 C2' DT D 10 3477 2362 2976 62 119 -353 C ATOM 1208 C1' DT D 10 -42.786 6.185 170.617 1.00 18.01 C ANISOU 1208 C1' DT D 10 2781 1744 2319 48 151 -351 C ATOM 1209 N1 DT D 10 -42.298 7.082 169.551 1.00 13.42 N ANISOU 1209 N1 DT D 10 2152 1207 1738 62 134 -374 N ATOM 1210 C2 DT D 10 -43.072 7.300 168.437 1.00 18.55 C ANISOU 1210 C2 DT D 10 2752 1885 2409 48 145 -389 C ATOM 1211 O2 DT D 10 -44.145 6.758 168.245 1.00 16.87 O ANISOU 1211 O2 DT D 10 2526 1664 2218 24 165 -387 O ATOM 1212 N3 DT D 10 -42.540 8.175 167.533 1.00 15.47 N ANISOU 1212 N3 DT D 10 2327 1535 2016 62 129 -408 N ATOM 1213 C4 DT D 10 -41.336 8.845 167.625 1.00 16.47 C ANISOU 1213 C4 DT D 10 2460 1674 2122 86 106 -412 C ATOM 1214 O4 DT D 10 -40.955 9.608 166.744 1.00 15.07 O ANISOU 1214 O4 DT D 10 2250 1532 1943 95 97 -428 O ATOM 1215 C5 DT D 10 -40.570 8.580 168.821 1.00 14.97 C ANISOU 1215 C5 DT D 10 2320 1454 1914 99 94 -397 C ATOM 1216 C7 DT D 10 -39.237 9.255 169.046 1.00 9.72 C ANISOU 1216 C7 DT D 10 1662 800 1230 123 67 -402 C ATOM 1217 C6 DT D 10 -41.088 7.720 169.717 1.00 16.30 C ANISOU 1217 C6 DT D 10 2527 1584 2084 87 108 -378 C ATOM 1218 P DA D 11 -43.113 2.314 172.354 1.00 36.02 P ANISOU 1218 P DA D 11 5190 3876 4621 16 151 -315 P ATOM 1219 OP1 DA D 11 -44.139 1.724 173.241 1.00 38.09 O ANISOU 1219 OP1 DA D 11 5488 4101 4881 -14 190 -287 O ATOM 1220 OP2 DA D 11 -41.689 1.967 172.490 1.00 37.70 O ANISOU 1220 OP2 DA D 11 5429 4072 4822 50 104 -324 O ATOM 1221 O5' DA D 11 -43.507 2.012 170.855 1.00 29.29 O ANISOU 1221 O5' DA D 11 4277 3047 3806 4 144 -346 O ATOM 1222 C5' DA D 11 -44.790 2.403 170.409 1.00 30.59 C ANISOU 1222 C5' DA D 11 4400 3236 3988 -24 179 -346 C ATOM 1223 C4' DA D 11 -44.954 2.125 168.938 1.00 28.16 C ANISOU 1223 C4' DA D 11 4040 2950 3711 -30 161 -378 C ATOM 1224 O4' DA D 11 -44.401 3.220 168.168 1.00 33.07 O ANISOU 1224 O4' DA D 11 4622 3619 4323 -8 145 -397 O ATOM 1225 C3' DA D 11 -44.264 0.862 168.444 1.00 27.83 C ANISOU 1225 C3' DA D 11 4012 2876 3686 -22 127 -398 C ATOM 1226 O3' DA D 11 -45.164 0.173 167.627 1.00 33.68 O ANISOU 1226 O3' DA D 11 4725 3613 4460 -51 133 -413 O ATOM 1227 C2' DA D 11 -43.066 1.396 167.649 1.00 25.36 C ANISOU 1227 C2' DA D 11 3675 2595 3364 12 92 -424 C ATOM 1228 C1' DA D 11 -43.626 2.709 167.112 1.00 23.30 C ANISOU 1228 C1' DA D 11 3368 2387 3099 7 110 -427 C ATOM 1229 N9 DA D 11 -42.611 3.714 166.790 1.00 18.73 N ANISOU 1229 N9 DA D 11 2773 1843 2499 37 91 -438 N ATOM 1230 C8 DA D 11 -41.493 4.018 167.526 1.00 21.90 C ANISOU 1230 C8 DA D 11 3205 2239 2878 63 74 -430 C ATOM 1231 N7 DA D 11 -40.762 4.987 167.016 1.00 15.72 N ANISOU 1231 N7 DA D 11 2396 1494 2083 82 61 -443 N ATOM 1232 C5 DA D 11 -41.452 5.355 165.869 1.00 11.82 C ANISOU 1232 C5 DA D 11 1856 1033 1603 69 70 -459 C ATOM 1233 C6 DA D 11 -41.206 6.334 164.897 1.00 15.65 C ANISOU 1233 C6 DA D 11 2301 1563 2082 78 66 -476 C ATOM 1234 N6 DA D 11 -40.148 7.132 164.924 1.00 13.35 N ANISOU 1234 N6 DA D 11 2008 1292 1773 100 51 -480 N ATOM 1235 N1 DA D 11 -42.089 6.450 163.876 1.00 13.24 N ANISOU 1235 N1 DA D 11 1959 1281 1791 62 74 -489 N ATOM 1236 C2 DA D 11 -43.152 5.632 163.848 1.00 13.65 C ANISOU 1236 C2 DA D 11 2009 1312 1865 37 87 -487 C ATOM 1237 N3 DA D 11 -43.499 4.676 164.719 1.00 16.69 N ANISOU 1237 N3 DA D 11 2428 1655 2260 24 95 -472 N ATOM 1238 C4 DA D 11 -42.600 4.589 165.716 1.00 18.70 C ANISOU 1238 C4 DA D 11 2723 1887 2496 42 87 -457 C ATOM 1239 P DT D 12 -44.845 -1.303 167.085 1.00 36.43 P ANISOU 1239 P DT D 12 5088 3920 4832 -53 106 -433 P ATOM 1240 OP1 DT D 12 -46.155 -1.994 167.215 1.00 35.40 O ANISOU 1240 OP1 DT D 12 4956 3765 4728 -97 133 -422 O ATOM 1241 OP2 DT D 12 -43.615 -1.858 167.707 1.00 32.63 O ANISOU 1241 OP2 DT D 12 4657 3405 4336 -23 79 -428 O ATOM 1242 O5' DT D 12 -44.524 -1.050 165.548 1.00 29.00 O ANISOU 1242 O5' DT D 12 4097 3019 3903 -41 80 -472 O ATOM 1243 C5' DT D 12 -45.373 -0.201 164.803 1.00 27.66 C ANISOU 1243 C5' DT D 12 3875 2895 3741 -56 95 -480 C ATOM 1244 C4' DT D 12 -44.699 0.240 163.527 1.00 27.05 C ANISOU 1244 C4' DT D 12 3763 2856 3660 -33 68 -513 C ATOM 1245 O4' DT D 12 -43.746 1.296 163.807 1.00 23.81 O ANISOU 1245 O4' DT D 12 3353 2473 3220 -2 63 -507 O ATOM 1246 C3' DT D 12 -43.917 -0.853 162.800 1.00 25.45 C ANISOU 1246 C3' DT D 12 3571 2630 3469 -19 35 -542 C ATOM 1247 O3' DT D 12 -44.578 -1.150 161.564 1.00 28.97 O ANISOU 1247 O3' DT D 12 3983 3090 3936 -37 28 -570 O ATOM 1248 C2' DT D 12 -42.511 -0.239 162.572 1.00 18.88 C ANISOU 1248 C2' DT D 12 2737 1823 2614 22 15 -555 C ATOM 1249 C1' DT D 12 -42.758 1.247 162.815 1.00 14.15 C ANISOU 1249 C1' DT D 12 2115 1268 1995 23 34 -538 C ATOM 1250 N1 DT D 12 -41.533 2.035 163.278 1.00 21.07 N ANISOU 1250 N1 DT D 12 3002 2160 2845 55 24 -532 N ATOM 1251 C2 DT D 12 -41.100 3.092 162.506 1.00 16.76 C ANISOU 1251 C2 DT D 12 2422 1661 2286 69 20 -546 C ATOM 1252 O2 DT D 12 -41.646 3.423 161.470 1.00 20.23 O ANISOU 1252 O2 DT D 12 2827 2130 2731 59 23 -562 O ATOM 1253 N3 DT D 12 -39.987 3.745 162.979 1.00 11.94 N ANISOU 1253 N3 DT D 12 1820 1061 1655 95 11 -540 N ATOM 1254 C4 DT D 12 -39.290 3.474 164.130 1.00 20.11 C ANISOU 1254 C4 DT D 12 2894 2065 2681 110 2 -523 C ATOM 1255 O4 DT D 12 -38.306 4.150 164.478 1.00 17.63 O ANISOU 1255 O4 DT D 12 2583 1765 2350 132 -9 -520 O ATOM 1256 C5 DT D 12 -39.785 2.345 164.902 1.00 16.67 C ANISOU 1256 C5 DT D 12 2497 1581 2257 97 6 -508 C ATOM 1257 C7 DT D 12 -39.088 1.943 166.169 1.00 15.38 C ANISOU 1257 C7 DT D 12 2383 1380 2082 113 -6 -488 C ATOM 1258 C6 DT D 12 -40.872 1.685 164.444 1.00 17.56 C ANISOU 1258 C6 DT D 12 2600 1681 2390 69 18 -513 C ATOM 1259 P DT D 13 -43.916 -2.149 160.498 1.00 36.46 P ANISOU 1259 P DT D 13 4934 4024 4896 -23 -4 -608 P ATOM 1260 OP1 DT D 13 -45.047 -2.857 159.859 1.00 49.27 O ANISOU 1260 OP1 DT D 13 6542 5633 6546 -59 -5 -622 O ATOM 1261 OP2 DT D 13 -42.812 -2.900 161.140 1.00 36.11 O ANISOU 1261 OP2 DT D 13 4934 3941 4847 3 -20 -606 O ATOM 1262 O5' DT D 13 -43.271 -1.160 159.419 1.00 31.78 O ANISOU 1262 O5' DT D 13 4306 3486 4285 2 -16 -632 O ATOM 1263 C5' DT D 13 -43.990 0.009 159.071 1.00 26.14 C ANISOU 1263 C5' DT D 13 3554 2817 3562 -9 -1 -626 C ATOM 1264 C4' DT D 13 -43.192 0.885 158.142 1.00 25.87 C ANISOU 1264 C4' DT D 13 3496 2827 3506 17 -13 -645 C ATOM 1265 O4' DT D 13 -42.159 1.611 158.872 1.00 24.03 O ANISOU 1265 O4' DT D 13 3275 2604 3251 44 -9 -630 O ATOM 1266 C3' DT D 13 -42.486 0.151 157.023 1.00 18.70 C ANISOU 1266 C3' DT D 13 2587 1916 2600 33 -37 -684 C ATOM 1267 O3' DT D 13 -42.651 0.899 155.864 1.00 30.40 O ANISOU 1267 O3' DT D 13 4038 3444 4071 34 -40 -702 O ATOM 1268 C2' DT D 13 -41.025 0.145 157.476 1.00 26.58 C ANISOU 1268 C2' DT D 13 3606 2909 3586 68 -45 -684 C ATOM 1269 C1' DT D 13 -40.935 1.489 158.177 1.00 22.01 C ANISOU 1269 C1' DT D 13 3017 2359 2986 73 -28 -656 C ATOM 1270 N1 DT D 13 -39.834 1.602 159.177 1.00 19.66 N ANISOU 1270 N1 DT D 13 2744 2049 2679 98 -32 -641 N ATOM 1271 C2 DT D 13 -38.959 2.669 159.106 1.00 21.41 C ANISOU 1271 C2 DT D 13 2950 2305 2879 119 -32 -640 C ATOM 1272 O2 DT D 13 -39.002 3.512 158.231 1.00 22.67 O ANISOU 1272 O2 DT D 13 3080 2505 3027 119 -27 -651 O ATOM 1273 N3 DT D 13 -38.010 2.703 160.090 1.00 14.36 N ANISOU 1273 N3 DT D 13 2080 1397 1980 139 -39 -627 N ATOM 1274 C4 DT D 13 -37.880 1.824 161.143 1.00 16.54 C ANISOU 1274 C4 DT D 13 2394 1626 2265 142 -46 -612 C ATOM 1275 O4 DT D 13 -37.002 1.945 161.975 1.00 17.14 O ANISOU 1275 O4 DT D 13 2488 1691 2332 163 -56 -600 O ATOM 1276 C5 DT D 13 -38.836 0.727 161.164 1.00 19.23 C ANISOU 1276 C5 DT D 13 2752 1930 2625 119 -43 -611 C ATOM 1277 C7 DT D 13 -38.774 -0.325 162.243 1.00 19.15 C ANISOU 1277 C7 DT D 13 2788 1865 2624 119 -49 -594 C ATOM 1278 C6 DT D 13 -39.762 0.687 160.201 1.00 19.12 C ANISOU 1278 C6 DT D 13 2713 1932 2621 97 -35 -626 C ATOM 1279 P DC D 14 -42.203 0.318 154.446 1.00 35.67 P ANISOU 1279 P DC D 14 4699 4122 4733 45 -61 -736 P ATOM 1280 OP1 DC D 14 -43.363 0.607 153.566 1.00 44.78 O ANISOU 1280 OP1 DC D 14 5827 5295 5892 21 -64 -752 O ATOM 1281 OP2 DC D 14 -41.667 -1.046 154.640 1.00 30.53 O ANISOU 1281 OP2 DC D 14 4078 3429 4093 52 -72 -739 O ATOM 1282 O5' DC D 14 -40.998 1.267 153.989 1.00 33.52 O ANISOU 1282 O5' DC D 14 4415 3894 4428 75 -57 -730 O ATOM 1283 C5' DC D 14 -41.198 2.670 153.922 1.00 28.34 C ANISOU 1283 C5' DC D 14 3737 3277 3755 75 -46 -721 C ATOM 1284 C4' DC D 14 -39.893 3.384 153.643 1.00 27.64 C ANISOU 1284 C4' DC D 14 3642 3220 3640 101 -42 -714 C ATOM 1285 O4' DC D 14 -39.043 3.356 154.825 1.00 27.51 O ANISOU 1285 O4' DC D 14 3642 3184 3625 116 -39 -697 O ATOM 1286 C3' DC D 14 -39.057 2.784 152.520 1.00 28.45 C ANISOU 1286 C3' DC D 14 3744 3334 3733 115 -51 -729 C ATOM 1287 O3' DC D 14 -38.490 3.845 151.785 1.00 35.62 O ANISOU 1287 O3' DC D 14 4633 4285 4616 125 -44 -727 O ATOM 1288 C2' DC D 14 -37.993 1.976 153.274 1.00 27.17 C ANISOU 1288 C2' DC D 14 3601 3142 3580 135 -55 -724 C ATOM 1289 C1' DC D 14 -37.761 2.880 154.471 1.00 21.41 C ANISOU 1289 C1' DC D 14 2873 2415 2848 139 -46 -702 C ATOM 1290 N1 DC D 14 -37.179 2.213 155.672 1.00 18.75 N ANISOU 1290 N1 DC D 14 2560 2039 2523 151 -52 -692 N ATOM 1291 C2 DC D 14 -36.091 2.801 156.320 1.00 17.30 C ANISOU 1291 C2 DC D 14 2375 1865 2331 171 -52 -679 C ATOM 1292 O2 DC D 14 -35.609 3.838 155.859 1.00 24.12 O ANISOU 1292 O2 DC D 14 3217 2768 3179 177 -44 -678 O ATOM 1293 N3 DC D 14 -35.594 2.224 157.434 1.00 18.65 N ANISOU 1293 N3 DC D 14 2572 2002 2514 183 -61 -670 N ATOM 1294 C4 DC D 14 -36.138 1.110 157.902 1.00 21.74 C ANISOU 1294 C4 DC D 14 2990 2348 2922 175 -68 -670 C ATOM 1295 N4 DC D 14 -35.605 0.574 158.996 1.00 19.03 N ANISOU 1295 N4 DC D 14 2676 1969 2587 189 -78 -659 N ATOM 1296 C5 DC D 14 -37.258 0.492 157.262 1.00 21.74 C ANISOU 1296 C5 DC D 14 2991 2336 2932 152 -66 -683 C ATOM 1297 C6 DC D 14 -37.750 1.082 156.170 1.00 15.87 C ANISOU 1297 C6 DC D 14 2221 1630 2180 141 -59 -694 C ATOM 1298 P DA D 15 -37.678 3.572 150.432 1.00 41.26 P ANISOU 1298 P DA D 15 5342 5021 5314 139 -46 -744 P ATOM 1299 OP1 DA D 15 -37.941 4.753 149.572 1.00 40.13 O ANISOU 1299 OP1 DA D 15 5182 4918 5147 134 -39 -743 O ATOM 1300 OP2 DA D 15 -37.924 2.183 149.992 1.00 46.36 O ANISOU 1300 OP2 DA D 15 6002 5638 5973 136 -59 -763 O ATOM 1301 O5' DA D 15 -36.154 3.632 150.885 1.00 38.69 O ANISOU 1301 O5' DA D 15 5016 4698 4988 163 -40 -737 O ATOM 1302 C5' DA D 15 -35.726 4.703 151.682 1.00 31.87 C ANISOU 1302 C5' DA D 15 4144 3848 4118 168 -31 -718 C ATOM 1303 C4' DA D 15 -34.230 4.703 151.797 1.00 29.65 C ANISOU 1303 C4' DA D 15 3856 3573 3836 191 -28 -719 C ATOM 1304 O4' DA D 15 -33.825 4.016 153.010 1.00 36.54 O ANISOU 1304 O4' DA D 15 4743 4411 4728 201 -38 -713 O ATOM 1305 C3' DA D 15 -33.508 4.021 150.656 1.00 26.58 C ANISOU 1305 C3' DA D 15 3463 3193 3445 204 -28 -741 C ATOM 1306 O3' DA D 15 -32.366 4.798 150.337 1.00 32.49 O ANISOU 1306 O3' DA D 15 4191 3972 4183 217 -17 -741 O ATOM 1307 C2' DA D 15 -33.157 2.631 151.240 1.00 27.90 C ANISOU 1307 C2' DA D 15 3647 3320 3635 217 -41 -748 C ATOM 1308 C1' DA D 15 -32.954 2.939 152.713 1.00 28.46 C ANISOU 1308 C1' DA D 15 3724 3374 3717 220 -46 -729 C ATOM 1309 N9 DA D 15 -33.299 1.859 153.641 1.00 19.42 N ANISOU 1309 N9 DA D 15 2604 2181 2591 221 -59 -725 N ATOM 1310 C8 DA D 15 -34.379 1.027 153.589 1.00 19.24 C ANISOU 1310 C8 DA D 15 2601 2130 2578 204 -64 -730 C ATOM 1311 N7 DA D 15 -34.452 0.180 154.598 1.00 25.02 N ANISOU 1311 N7 DA D 15 3359 2820 3328 207 -75 -723 N ATOM 1312 C5 DA D 15 -33.364 0.509 155.385 1.00 16.48 C ANISOU 1312 C5 DA D 15 2275 1740 2248 228 -78 -713 C ATOM 1313 C6 DA D 15 -32.886 -0.005 156.599 1.00 20.60 C ANISOU 1313 C6 DA D 15 2819 2226 2782 242 -91 -702 C ATOM 1314 N6 DA D 15 -33.491 -0.998 157.269 1.00 17.66 N ANISOU 1314 N6 DA D 15 2480 1807 2424 235 -99 -697 N ATOM 1315 N1 DA D 15 -31.762 0.547 157.114 1.00 19.32 N ANISOU 1315 N1 DA D 15 2646 2077 2619 264 -97 -697 N ATOM 1316 C2 DA D 15 -31.174 1.544 156.448 1.00 17.30 C ANISOU 1316 C2 DA D 15 2357 1866 2351 268 -87 -702 C ATOM 1317 N3 DA D 15 -31.534 2.115 155.300 1.00 21.31 N ANISOU 1317 N3 DA D 15 2845 2409 2845 255 -72 -711 N ATOM 1318 C4 DA D 15 -32.647 1.546 154.816 1.00 21.59 C ANISOU 1318 C4 DA D 15 2893 2431 2880 236 -69 -716 C ATOM 1319 P DC D 16 -31.569 4.590 148.960 1.00 47.27 P ANISOU 1319 P DC D 16 6052 5865 6042 228 -7 -763 P ATOM 1320 OP1 DC D 16 -31.155 5.924 148.456 1.00 46.61 O ANISOU 1320 OP1 DC D 16 5951 5821 5939 224 10 -757 O ATOM 1321 OP2 DC D 16 -32.351 3.664 148.111 1.00 48.42 O ANISOU 1321 OP2 DC D 16 6214 5998 6186 221 -13 -778 O ATOM 1322 O5' DC D 16 -30.256 3.853 149.437 1.00 42.17 O ANISOU 1322 O5' DC D 16 5400 5205 5418 254 -11 -772 O ATOM 1323 C5' DC D 16 -29.568 4.363 150.536 1.00 41.45 C ANISOU 1323 C5' DC D 16 5299 5113 5338 263 -14 -760 C ATOM 1324 C4' DC D 16 -28.661 3.313 151.104 1.00 45.92 C ANISOU 1324 C4' DC D 16 5866 5652 5928 288 -28 -771 C ATOM 1325 O4' DC D 16 -29.370 2.505 152.078 1.00 46.85 O ANISOU 1325 O4' DC D 16 6011 5728 6060 285 -45 -761 O ATOM 1326 C3' DC D 16 -28.106 2.326 150.067 1.00 51.35 C ANISOU 1326 C3' DC D 16 6553 6339 6621 304 -24 -796 C ATOM 1327 O3' DC D 16 -26.709 2.291 150.182 1.00 55.77 O ANISOU 1327 O3' DC D 16 7089 6907 7194 329 -23 -808 O ATOM 1328 C2' DC D 16 -28.733 0.989 150.485 1.00 49.55 C ANISOU 1328 C2' DC D 16 6353 6066 6407 305 -42 -798 C ATOM 1329 C1' DC D 16 -28.843 1.213 151.979 1.00 41.03 C ANISOU 1329 C1' DC D 16 5283 4966 5341 305 -56 -777 C ATOM 1330 N1 DC D 16 -29.704 0.223 152.707 1.00 24.03 N ANISOU 1330 N1 DC D 16 3163 2768 3200 297 -71 -770 N ATOM 1331 C2 DC D 16 -29.339 -0.167 153.998 1.00 30.85 C ANISOU 1331 C2 DC D 16 4041 3600 4081 311 -88 -759 C ATOM 1332 O2 DC D 16 -28.333 0.342 154.513 1.00 40.29 O ANISOU 1332 O2 DC D 16 5219 4807 5282 328 -93 -756 O ATOM 1333 N3 DC D 16 -30.101 -1.077 154.655 1.00 27.50 N ANISOU 1333 N3 DC D 16 3650 3133 3667 303 -99 -751 N ATOM 1334 C4 DC D 16 -31.181 -1.600 154.061 1.00 24.94 C ANISOU 1334 C4 DC D 16 3340 2796 3339 282 -95 -757 C ATOM 1335 N4 DC D 16 -31.910 -2.502 154.754 1.00 19.83 N ANISOU 1335 N4 DC D 16 2726 2104 2705 272 -105 -750 N ATOM 1336 C5 DC D 16 -31.566 -1.218 152.736 1.00 22.41 C ANISOU 1336 C5 DC D 16 3004 2509 3003 269 -81 -770 C ATOM 1337 C6 DC D 16 -30.796 -0.320 152.100 1.00 21.63 C ANISOU 1337 C6 DC D 16 2875 2452 2891 278 -69 -775 C ATOM 1338 P DA D 17 -25.797 1.722 148.993 1.00 60.18 P ANISOU 1338 P DA D 17 7633 7479 7752 349 -9 -836 P ATOM 1339 OP1 DA D 17 -25.761 2.764 147.943 1.00 59.08 O ANISOU 1339 OP1 DA D 17 7479 7382 7588 335 16 -838 O ATOM 1340 OP2 DA D 17 -26.239 0.350 148.645 1.00 62.16 O ANISOU 1340 OP2 DA D 17 7911 7699 8010 355 -18 -848 O ATOM 1341 O5' DA D 17 -24.375 1.594 149.699 1.00 50.42 O ANISOU 1341 O5' DA D 17 6371 6241 6543 378 -17 -844 O ATOM 1342 C5' DA D 17 -24.150 2.262 150.932 1.00 44.02 C ANISOU 1342 C5' DA D 17 5553 5429 5744 379 -31 -828 C ATOM 1343 C4' DA D 17 -23.587 1.304 151.962 1.00 48.35 C ANISOU 1343 C4' DA D 17 6108 5941 6321 405 -58 -831 C ATOM 1344 O4' DA D 17 -24.670 0.599 152.615 1.00 48.02 O ANISOU 1344 O4' DA D 17 6105 5860 6279 394 -75 -815 O ATOM 1345 C3' DA D 17 -22.661 0.231 151.393 1.00 59.45 C ANISOU 1345 C3' DA D 17 7504 7339 7745 435 -59 -857 C ATOM 1346 O3' DA D 17 -21.488 0.128 152.193 1.00 71.19 O ANISOU 1346 O3' DA D 17 8968 8821 9259 464 -77 -863 O ATOM 1347 C2' DA D 17 -23.505 -1.045 151.447 1.00 51.55 C ANISOU 1347 C2' DA D 17 6543 6297 6746 434 -72 -855 C ATOM 1348 C1' DA D 17 -24.389 -0.780 152.649 1.00 43.74 C ANISOU 1348 C1' DA D 17 5579 5284 5755 416 -89 -828 C ATOM 1349 N9 DA D 17 -25.657 -1.519 152.629 1.00 28.54 N ANISOU 1349 N9 DA D 17 3693 3329 3823 397 -93 -820 N ATOM 1350 C8 DA D 17 -26.595 -1.525 151.634 1.00 23.33 C ANISOU 1350 C8 DA D 17 3042 2678 3144 374 -77 -824 C ATOM 1351 N7 DA D 17 -27.639 -2.282 151.895 1.00 32.02 N ANISOU 1351 N7 DA D 17 4176 3745 4247 359 -86 -817 N ATOM 1352 C5 DA D 17 -27.358 -2.812 153.151 1.00 21.67 C ANISOU 1352 C5 DA D 17 2880 2398 2955 373 -107 -806 C ATOM 1353 C6 DA D 17 -28.067 -3.696 153.996 1.00 25.77 C ANISOU 1353 C6 DA D 17 3437 2870 3485 367 -123 -794 C ATOM 1354 N6 DA D 17 -29.255 -4.229 153.681 1.00 30.49 N ANISOU 1354 N6 DA D 17 4060 3448 4078 342 -120 -794 N ATOM 1355 N1 DA D 17 -27.511 -4.011 155.185 1.00 22.03 N ANISOU 1355 N1 DA D 17 2975 2368 3027 386 -143 -783 N ATOM 1356 C2 DA D 17 -26.318 -3.484 155.499 1.00 25.35 C ANISOU 1356 C2 DA D 17 3369 2808 3454 411 -150 -786 C ATOM 1357 N3 DA D 17 -25.558 -2.652 154.789 1.00 31.88 N ANISOU 1357 N3 DA D 17 4157 3680 4276 418 -137 -799 N ATOM 1358 C4 DA D 17 -26.144 -2.348 153.615 1.00 25.22 C ANISOU 1358 C4 DA D 17 3305 2863 3415 398 -113 -807 C ATOM 1359 P DC D 18 -20.185 -0.604 151.610 1.00 71.67 P ANISOU 1359 P DC D 18 9001 8887 9342 499 -74 -893 P ATOM 1360 OP1 DC D 18 -18.995 0.131 152.102 1.00 71.35 O ANISOU 1360 OP1 DC D 18 8919 8870 9323 515 -79 -900 O ATOM 1361 OP2 DC D 18 -20.397 -0.780 150.152 1.00 69.21 O ANISOU 1361 OP2 DC D 18 8690 8594 9011 491 -43 -908 O ATOM 1362 O5' DC D 18 -20.241 -2.046 152.306 1.00 67.88 O ANISOU 1362 O5' DC D 18 8552 8356 8883 522 -104 -893 O ATOM 1363 C5' DC D 18 -20.363 -2.129 153.720 1.00 63.20 C ANISOU 1363 C5' DC D 18 7978 7733 8302 528 -137 -874 C ATOM 1364 C4' DC D 18 -20.834 -3.506 154.139 1.00 61.25 C ANISOU 1364 C4' DC D 18 7773 7435 8063 538 -158 -869 C ATOM 1365 O4' DC D 18 -22.250 -3.640 153.885 1.00 61.02 O ANISOU 1365 O4' DC D 18 7780 7393 8012 504 -147 -856 O ATOM 1366 C3' DC D 18 -20.169 -4.670 153.394 1.00 62.96 C ANISOU 1366 C3' DC D 18 7986 7641 8295 567 -156 -896 C ATOM 1367 O3' DC D 18 -19.332 -5.402 154.280 1.00 75.26 O ANISOU 1367 O3' DC D 18 9545 9169 9881 602 -188 -898 O ATOM 1368 C2' DC D 18 -21.342 -5.529 152.896 1.00 54.42 C ANISOU 1368 C2' DC D 18 6947 6531 7198 547 -149 -893 C ATOM 1369 C1' DC D 18 -22.510 -5.004 153.724 1.00 51.03 C ANISOU 1369 C1' DC D 18 6545 6089 6755 514 -155 -863 C ATOM 1370 N1 DC D 18 -23.826 -5.192 153.057 1.00 33.81 N ANISOU 1370 N1 DC D 18 4392 3903 4553 481 -139 -859 N ATOM 1371 C2 DC D 18 -24.790 -5.987 153.668 1.00 31.56 C ANISOU 1371 C2 DC D 18 4149 3572 4269 468 -153 -845 C ATOM 1372 O2 DC D 18 -24.536 -6.488 154.773 1.00 32.04 O ANISOU 1372 O2 DC D 18 4229 3599 4347 483 -177 -833 O ATOM 1373 N3 DC D 18 -25.978 -6.183 153.038 1.00 29.22 N ANISOU 1373 N3 DC D 18 3873 3270 3957 438 -140 -845 N ATOM 1374 C4 DC D 18 -26.198 -5.618 151.847 1.00 30.01 C ANISOU 1374 C4 DC D 18 3956 3408 4039 424 -118 -857 C ATOM 1375 N4 DC D 18 -27.376 -5.834 151.254 1.00 29.16 N ANISOU 1375 N4 DC D 18 3868 3293 3917 396 -110 -858 N ATOM 1376 C5 DC D 18 -25.214 -4.813 151.206 1.00 35.72 C ANISOU 1376 C5 DC D 18 4638 4176 4757 438 -102 -870 C ATOM 1377 C6 DC D 18 -24.052 -4.632 151.840 1.00 33.44 C ANISOU 1377 C6 DC D 18 4328 3893 4486 466 -112 -871 C ATOM 1378 P DC D 19 -18.230 -6.422 153.696 1.00 77.70 P ANISOU 1378 P DC D 19 9836 9472 10213 643 -190 -928 P ATOM 1379 OP1 DC D 19 -17.084 -6.383 154.638 1.00 75.76 O ANISOU 1379 OP1 DC D 19 9566 9222 9997 677 -221 -929 O ATOM 1380 OP2 DC D 19 -18.059 -6.175 152.237 1.00 67.43 O ANISOU 1380 OP2 DC D 19 8511 8209 8901 636 -151 -950 O ATOM 1381 O5' DC D 19 -18.933 -7.849 153.808 1.00 75.04 O ANISOU 1381 O5' DC D 19 9553 9082 9878 646 -204 -924 O ATOM 1382 C5' DC D 19 -19.197 -8.430 155.083 1.00 69.09 C ANISOU 1382 C5' DC D 19 8836 8282 9134 653 -239 -903 C ATOM 1383 C4' DC D 19 -20.029 -9.681 154.896 1.00 62.74 C ANISOU 1383 C4' DC D 19 8081 7433 8326 646 -240 -902 C ATOM 1384 O4' DC D 19 -21.387 -9.297 154.578 1.00 57.45 O ANISOU 1384 O4' DC D 19 7432 6765 7630 601 -220 -889 O ATOM 1385 C3' DC D 19 -19.567 -10.558 153.723 1.00 62.57 C ANISOU 1385 C3' DC D 19 8051 7410 8311 666 -225 -933 C ATOM 1386 O3' DC D 19 -18.810 -11.685 154.190 1.00 68.87 O ANISOU 1386 O3' DC D 19 8862 8171 9135 706 -252 -941 O ATOM 1387 C2' DC D 19 -20.860 -10.997 153.031 1.00 56.26 C ANISOU 1387 C2' DC D 19 7290 6596 7491 632 -207 -933 C ATOM 1388 C1' DC D 19 -21.979 -10.330 153.845 1.00 52.00 C ANISOU 1388 C1' DC D 19 6772 6051 6937 594 -211 -901 C ATOM 1389 N1 DC D 19 -23.043 -9.784 152.962 1.00 38.13 N ANISOU 1389 N1 DC D 19 5017 4317 5154 555 -184 -901 N ATOM 1390 C2 DC D 19 -24.367 -10.229 153.109 1.00 27.55 C ANISOU 1390 C2 DC D 19 3718 2946 3805 522 -185 -888 C ATOM 1391 O2 DC D 19 -24.647 -11.011 154.030 1.00 30.99 O ANISOU 1391 O2 DC D 19 4189 3335 4253 525 -205 -874 O ATOM 1392 N3 DC D 19 -25.313 -9.760 152.258 1.00 29.65 N ANISOU 1392 N3 DC D 19 3984 3234 4049 489 -163 -891 N ATOM 1393 C4 DC D 19 -24.970 -8.913 151.277 1.00 34.65 C ANISOU 1393 C4 DC D 19 4583 3917 4668 487 -141 -904 C ATOM 1394 N4 DC D 19 -25.932 -8.480 150.458 1.00 36.97 N ANISOU 1394 N4 DC D 19 4879 4228 4938 455 -124 -905 N ATOM 1395 C5 DC D 19 -23.624 -8.476 151.093 1.00 34.63 C ANISOU 1395 C5 DC D 19 4541 3945 4673 518 -136 -917 C ATOM 1396 C6 DC D 19 -22.700 -8.942 151.943 1.00 32.40 C ANISOU 1396 C6 DC D 19 4254 3641 4414 551 -158 -916 C TER 1397 DC D 19 ATOM 1398 O5' DG E 1 -36.233 -14.946 152.001 1.00 45.28 O ANISOU 1398 O5' DG E 1 6226 4926 6050 185 -185 -875 O ATOM 1399 C5' DG E 1 -34.870 -14.656 151.720 1.00 33.56 C ANISOU 1399 C5' DG E 1 4723 3473 4557 230 -182 -883 C ATOM 1400 C4' DG E 1 -34.007 -15.061 152.892 1.00 30.21 C ANISOU 1400 C4' DG E 1 4315 3018 4147 258 -189 -865 C ATOM 1401 O4' DG E 1 -32.605 -14.818 152.582 1.00 25.92 O ANISOU 1401 O4' DG E 1 3747 2504 3597 303 -189 -875 O ATOM 1402 C3' DG E 1 -34.284 -14.297 154.178 1.00 29.71 C ANISOU 1402 C3' DG E 1 4250 2953 4085 247 -187 -832 C ATOM 1403 O3' DG E 1 -34.004 -15.135 155.291 1.00 30.57 O ANISOU 1403 O3' DG E 1 4394 3010 4211 258 -198 -815 O ATOM 1404 C2' DG E 1 -33.304 -13.129 154.079 1.00 23.17 C ANISOU 1404 C2' DG E 1 3381 2179 3241 276 -182 -830 C ATOM 1405 C1' DG E 1 -32.094 -13.771 153.379 1.00 26.37 C ANISOU 1405 C1' DG E 1 3781 2588 3649 316 -187 -853 C ATOM 1406 N9 DG E 1 -31.391 -12.827 152.508 1.00 22.57 N ANISOU 1406 N9 DG E 1 3259 2166 3151 334 -176 -867 N ATOM 1407 C8 DG E 1 -31.917 -12.166 151.410 1.00 26.81 C ANISOU 1407 C8 DG E 1 3775 2743 3670 314 -163 -880 C ATOM 1408 N7 DG E 1 -31.071 -11.354 150.835 1.00 27.11 N ANISOU 1408 N7 DG E 1 3779 2829 3695 335 -152 -888 N ATOM 1409 C5 DG E 1 -29.905 -11.485 151.595 1.00 20.78 C ANISOU 1409 C5 DG E 1 2970 2018 2905 370 -160 -881 C ATOM 1410 C6 DG E 1 -28.655 -10.849 151.453 1.00 22.48 C ANISOU 1410 C6 DG E 1 3152 2271 3119 402 -155 -887 C ATOM 1411 O6 DG E 1 -28.311 -10.018 150.596 1.00 31.46 O ANISOU 1411 O6 DG E 1 4257 3455 4240 405 -139 -897 O ATOM 1412 N1 DG E 1 -27.754 -11.249 152.442 1.00 17.65 N ANISOU 1412 N1 DG E 1 2544 1635 2526 433 -171 -878 N ATOM 1413 C2 DG E 1 -28.032 -12.155 153.435 1.00 17.99 C ANISOU 1413 C2 DG E 1 2625 1626 2586 433 -190 -865 C ATOM 1414 N2 DG E 1 -27.040 -12.413 154.289 1.00 22.61 N ANISOU 1414 N2 DG E 1 3210 2194 3186 466 -208 -858 N ATOM 1415 N3 DG E 1 -29.199 -12.773 153.575 1.00 19.10 N ANISOU 1415 N3 DG E 1 2801 1730 2728 402 -191 -858 N ATOM 1416 C4 DG E 1 -30.089 -12.386 152.629 1.00 16.64 C ANISOU 1416 C4 DG E 1 2480 1441 2400 371 -176 -868 C ATOM 1417 P DG E 2 -34.294 -14.646 156.797 1.00 37.57 P ANISOU 1417 P DG E 2 5295 3879 5102 247 -198 -779 P ATOM 1418 OP1 DG E 2 -34.308 -15.888 157.615 1.00 34.30 O ANISOU 1418 OP1 DG E 2 4927 3399 4705 249 -210 -767 O ATOM 1419 OP2 DG E 2 -35.423 -13.680 156.791 1.00 39.58 O ANISOU 1419 OP2 DG E 2 5535 4157 5348 208 -183 -770 O ATOM 1420 O5' DG E 2 -32.976 -13.854 157.202 1.00 32.62 O ANISOU 1420 O5' DG E 2 4643 3286 4465 289 -204 -771 O ATOM 1421 C5' DG E 2 -31.779 -14.591 157.404 1.00 36.27 C ANISOU 1421 C5' DG E 2 5113 3730 4936 332 -221 -776 C ATOM 1422 C4' DG E 2 -30.699 -13.706 157.967 1.00 40.53 C ANISOU 1422 C4' DG E 2 5628 4302 5471 364 -229 -766 C ATOM 1423 O4' DG E 2 -30.153 -12.873 156.917 1.00 40.55 O ANISOU 1423 O4' DG E 2 5582 4362 5461 376 -218 -786 O ATOM 1424 C3' DG E 2 -31.164 -12.759 159.070 1.00 43.99 C ANISOU 1424 C3' DG E 2 6071 4745 5900 346 -226 -735 C ATOM 1425 O3' DG E 2 -30.258 -12.839 160.145 1.00 54.09 O ANISOU 1425 O3' DG E 2 7363 6006 7182 378 -247 -718 O ATOM 1426 C2' DG E 2 -31.139 -11.383 158.396 1.00 39.48 C ANISOU 1426 C2' DG E 2 5452 4237 5311 340 -209 -743 C ATOM 1427 C1' DG E 2 -30.014 -11.557 157.395 1.00 39.43 C ANISOU 1427 C1' DG E 2 5415 4258 5307 374 -213 -771 C ATOM 1428 N9 DG E 2 -30.105 -10.669 156.251 1.00 29.38 N ANISOU 1428 N9 DG E 2 4103 3040 4020 365 -194 -787 N ATOM 1429 C8 DG E 2 -31.176 -10.529 155.408 1.00 23.93 C ANISOU 1429 C8 DG E 2 3411 2362 3320 332 -179 -796 C ATOM 1430 N7 DG E 2 -30.968 -9.671 154.445 1.00 26.01 N ANISOU 1430 N7 DG E 2 3638 2677 3569 332 -166 -810 N ATOM 1431 C5 DG E 2 -29.666 -9.222 154.657 1.00 21.81 C ANISOU 1431 C5 DG E 2 3082 2168 3038 367 -170 -810 C ATOM 1432 C6 DG E 2 -28.894 -8.274 153.930 1.00 22.38 C ANISOU 1432 C6 DG E 2 3111 2293 3098 381 -158 -822 C ATOM 1433 O6 DG E 2 -29.213 -7.632 152.919 1.00 27.62 O ANISOU 1433 O6 DG E 2 3755 2995 3746 366 -141 -832 O ATOM 1434 N1 DG E 2 -27.625 -8.116 154.478 1.00 23.79 N ANISOU 1434 N1 DG E 2 3273 2478 3287 415 -169 -821 N ATOM 1435 C2 DG E 2 -27.165 -8.776 155.597 1.00 30.50 C ANISOU 1435 C2 DG E 2 4145 3288 4154 436 -192 -809 C ATOM 1436 N2 DG E 2 -25.914 -8.481 155.984 1.00 32.83 N ANISOU 1436 N2 DG E 2 4417 3598 4459 469 -205 -811 N ATOM 1437 N3 DG E 2 -27.882 -9.660 156.291 1.00 34.10 N ANISOU 1437 N3 DG E 2 4645 3694 4619 424 -203 -796 N ATOM 1438 C4 DG E 2 -29.117 -9.834 155.760 1.00 25.86 C ANISOU 1438 C4 DG E 2 3616 2643 3567 388 -190 -798 C ATOM 1439 P DT E 3 -30.604 -12.183 161.570 1.00 53.79 P ANISOU 1439 P DT E 3 7348 5955 7135 366 -250 -682 P ATOM 1440 OP1 DT E 3 -30.256 -13.194 162.599 1.00 52.49 O ANISOU 1440 OP1 DT E 3 7230 5735 6979 383 -274 -664 O ATOM 1441 OP2 DT E 3 -31.977 -11.627 161.508 1.00 55.30 O ANISOU 1441 OP2 DT E 3 7542 6152 7319 319 -226 -674 O ATOM 1442 O5' DT E 3 -29.552 -10.979 161.661 1.00 47.56 O ANISOU 1442 O5' DT E 3 6518 5218 6336 393 -257 -683 O ATOM 1443 C5' DT E 3 -28.279 -11.111 161.033 1.00 41.49 C ANISOU 1443 C5' DT E 3 5718 4473 5576 433 -270 -706 C ATOM 1444 C4' DT E 3 -27.471 -9.833 161.162 1.00 50.08 C ANISOU 1444 C4' DT E 3 6765 5609 6654 449 -273 -706 C ATOM 1445 O4' DT E 3 -27.474 -9.101 159.907 1.00 49.91 O ANISOU 1445 O4' DT E 3 6697 5640 6626 440 -250 -728 O ATOM 1446 C3' DT E 3 -27.956 -8.849 162.229 1.00 51.41 C ANISOU 1446 C3' DT E 3 6946 5780 6807 431 -272 -677 C ATOM 1447 O3' DT E 3 -26.822 -8.326 162.907 1.00 57.17 O ANISOU 1447 O3' DT E 3 7663 6523 7537 463 -296 -672 O ATOM 1448 C2' DT E 3 -28.677 -7.775 161.409 1.00 47.09 C ANISOU 1448 C2' DT E 3 6366 5279 6247 400 -241 -685 C ATOM 1449 C1' DT E 3 -27.829 -7.755 160.147 1.00 43.78 C ANISOU 1449 C1' DT E 3 5903 4898 5834 421 -237 -716 C ATOM 1450 N1 DT E 3 -28.536 -7.226 158.926 1.00 24.80 N ANISOU 1450 N1 DT E 3 3473 2532 3419 394 -208 -730 N ATOM 1451 C2 DT E 3 -27.865 -6.361 158.100 1.00 31.48 C ANISOU 1451 C2 DT E 3 4274 3430 4259 404 -198 -746 C ATOM 1452 O2 DT E 3 -26.720 -5.995 158.312 1.00 40.52 O ANISOU 1452 O2 DT E 3 5394 4592 5409 432 -210 -751 O ATOM 1453 N3 DT E 3 -28.575 -5.940 157.006 1.00 29.66 N ANISOU 1453 N3 DT E 3 4026 3229 4015 379 -175 -757 N ATOM 1454 C4 DT E 3 -29.860 -6.297 156.666 1.00 18.58 C ANISOU 1454 C4 DT E 3 2643 1809 2607 347 -164 -756 C ATOM 1455 O4 DT E 3 -30.412 -5.863 155.662 1.00 23.89 O ANISOU 1455 O4 DT E 3 3298 2512 3268 328 -147 -767 O ATOM 1456 C5 DT E 3 -30.516 -7.207 157.585 1.00 20.26 C ANISOU 1456 C5 DT E 3 2900 1967 2831 336 -175 -741 C ATOM 1457 C7 DT E 3 -31.914 -7.658 157.323 1.00 22.40 C ANISOU 1457 C7 DT E 3 3193 2215 3101 300 -165 -741 C ATOM 1458 C6 DT E 3 -29.829 -7.628 158.656 1.00 15.22 C ANISOU 1458 C6 DT E 3 2283 1299 2203 360 -195 -728 C ATOM 1459 P DG E 4 -26.970 -7.450 164.248 1.00 48.99 P ANISOU 1459 P DG E 4 6649 5481 6484 456 -306 -642 P ATOM 1460 OP1 DG E 4 -25.867 -7.900 165.129 1.00 47.48 O ANISOU 1460 OP1 DG E 4 6473 5265 6300 495 -346 -635 O ATOM 1461 OP2 DG E 4 -28.374 -7.460 164.730 1.00 38.49 O ANISOU 1461 OP2 DG E 4 5358 4126 5142 416 -286 -619 O ATOM 1462 O5' DG E 4 -26.627 -5.988 163.729 1.00 41.71 O ANISOU 1462 O5' DG E 4 5674 4620 5553 453 -293 -653 O ATOM 1463 C5' DG E 4 -25.560 -5.822 162.824 1.00 36.64 C ANISOU 1463 C5' DG E 4 4983 4014 4924 478 -296 -680 C ATOM 1464 C4' DG E 4 -25.341 -4.358 162.546 1.00 38.93 C ANISOU 1464 C4' DG E 4 5231 4357 5203 470 -282 -685 C ATOM 1465 O4' DG E 4 -26.001 -3.987 161.309 1.00 43.91 O ANISOU 1465 O4' DG E 4 5836 5020 5826 444 -248 -698 O ATOM 1466 C3' DG E 4 -25.881 -3.426 163.623 1.00 29.56 C ANISOU 1466 C3' DG E 4 4068 3166 3997 452 -284 -658 C ATOM 1467 O3' DG E 4 -24.944 -2.399 163.838 1.00 33.61 O ANISOU 1467 O3' DG E 4 4549 3712 4509 468 -296 -662 O ATOM 1468 C2' DG E 4 -27.198 -2.919 163.029 1.00 25.75 C ANISOU 1468 C2' DG E 4 3585 2701 3500 411 -247 -654 C ATOM 1469 C1' DG E 4 -26.909 -2.930 161.530 1.00 36.11 C ANISOU 1469 C1' DG E 4 4851 4050 4818 413 -229 -683 C ATOM 1470 N9 DG E 4 -28.083 -3.190 160.694 1.00 28.68 N ANISOU 1470 N9 DG E 4 3916 3110 3872 382 -202 -687 N ATOM 1471 C8 DG E 4 -29.126 -4.038 160.974 1.00 20.93 C ANISOU 1471 C8 DG E 4 2973 2088 2892 363 -199 -677 C ATOM 1472 N7 DG E 4 -30.029 -4.078 160.027 1.00 21.94 N ANISOU 1472 N7 DG E 4 3093 2227 3015 337 -177 -687 N ATOM 1473 C5 DG E 4 -29.544 -3.215 159.050 1.00 13.79 C ANISOU 1473 C5 DG E 4 2017 1248 1976 341 -165 -703 C ATOM 1474 C6 DG E 4 -30.097 -2.852 157.789 1.00 20.65 C ANISOU 1474 C6 DG E 4 2862 2150 2835 322 -144 -717 C ATOM 1475 O6 DG E 4 -31.155 -3.244 157.265 1.00 25.67 O ANISOU 1475 O6 DG E 4 3509 2776 3468 298 -134 -721 O ATOM 1476 N1 DG E 4 -29.288 -1.944 157.113 1.00 19.64 N ANISOU 1476 N1 DG E 4 2694 2069 2698 333 -136 -727 N ATOM 1477 C2 DG E 4 -28.104 -1.439 157.598 1.00 20.82 C ANISOU 1477 C2 DG E 4 2825 2233 2853 358 -147 -727 C ATOM 1478 N2 DG E 4 -27.462 -0.568 156.799 1.00 25.91 N ANISOU 1478 N2 DG E 4 3430 2923 3490 362 -134 -739 N ATOM 1479 N3 DG E 4 -27.576 -1.768 158.779 1.00 21.30 N ANISOU 1479 N3 DG E 4 2905 2264 2925 377 -171 -716 N ATOM 1480 C4 DG E 4 -28.350 -2.656 159.447 1.00 18.48 C ANISOU 1480 C4 DG E 4 2590 1860 2572 367 -178 -703 C ATOM 1481 P DT E 5 -25.194 -1.275 164.952 1.00 32.02 P ANISOU 1481 P DT E 5 4367 3511 4287 456 -302 -639 P ATOM 1482 OP1 DT E 5 -23.854 -0.782 165.350 1.00 36.31 O ANISOU 1482 OP1 DT E 5 4886 4070 4841 487 -334 -648 O ATOM 1483 OP2 DT E 5 -26.192 -1.719 165.957 1.00 19.47 O ANISOU 1483 OP2 DT E 5 2837 1876 2682 439 -303 -610 O ATOM 1484 O5' DT E 5 -25.879 -0.125 164.111 1.00 25.80 O ANISOU 1484 O5' DT E 5 3548 2769 3484 425 -265 -644 O ATOM 1485 C5' DT E 5 -25.116 0.551 163.135 1.00 16.32 C ANISOU 1485 C5' DT E 5 2294 1616 2292 432 -255 -667 C ATOM 1486 C4' DT E 5 -25.981 1.539 162.417 1.00 20.61 C ANISOU 1486 C4' DT E 5 2819 2194 2817 399 -220 -666 C ATOM 1487 O4' DT E 5 -26.951 0.826 161.589 1.00 25.68 O ANISOU 1487 O4' DT E 5 3469 2830 3458 380 -197 -670 O ATOM 1488 C3' DT E 5 -26.823 2.457 163.338 1.00 17.80 C ANISOU 1488 C3' DT E 5 2492 1833 2438 376 -213 -641 C ATOM 1489 O3' DT E 5 -26.868 3.700 162.752 1.00 17.27 O ANISOU 1489 O3' DT E 5 2392 1810 2360 361 -193 -646 O ATOM 1490 C2' DT E 5 -28.208 1.803 163.250 1.00 14.85 C ANISOU 1490 C2' DT E 5 2149 1434 2059 351 -194 -630 C ATOM 1491 C1' DT E 5 -28.177 1.463 161.764 1.00 21.61 C ANISOU 1491 C1' DT E 5 2971 2318 2924 348 -177 -653 C ATOM 1492 N1 DT E 5 -29.317 0.626 161.252 1.00 18.68 N ANISOU 1492 N1 DT E 5 2617 1926 2554 328 -161 -654 N ATOM 1493 C2 DT E 5 -29.749 0.840 159.975 1.00 14.44 C ANISOU 1493 C2 DT E 5 2053 1421 2013 312 -139 -668 C ATOM 1494 O2 DT E 5 -29.197 1.633 159.213 1.00 17.62 O ANISOU 1494 O2 DT E 5 2420 1866 2410 315 -130 -680 O ATOM 1495 N3 DT E 5 -30.826 0.072 159.594 1.00 15.42 N ANISOU 1495 N3 DT E 5 2196 1524 2140 293 -130 -670 N ATOM 1496 C4 DT E 5 -31.499 -0.848 160.370 1.00 18.12 C ANISOU 1496 C4 DT E 5 2579 1817 2490 285 -137 -659 C ATOM 1497 O4 DT E 5 -32.454 -1.489 159.952 1.00 21.04 O ANISOU 1497 O4 DT E 5 2960 2169 2864 265 -128 -664 O ATOM 1498 C5 DT E 5 -31.005 -1.002 161.713 1.00 17.61 C ANISOU 1498 C5 DT E 5 2543 1721 2427 301 -156 -641 C ATOM 1499 C7 DT E 5 -31.661 -1.971 162.643 1.00 22.17 C ANISOU 1499 C7 DT E 5 3170 2243 3011 293 -164 -625 C ATOM 1500 C6 DT E 5 -29.958 -0.256 162.092 1.00 19.72 C ANISOU 1500 C6 DT E 5 2793 2009 2690 322 -169 -639 C ATOM 1501 P DG E 6 -26.447 5.025 163.535 1.00 15.10 P ANISOU 1501 P DG E 6 2115 1551 2072 361 -202 -637 P ATOM 1502 OP1 DG E 6 -24.996 5.001 163.738 1.00 17.14 O ANISOU 1502 OP1 DG E 6 2350 1814 2349 392 -232 -652 O ATOM 1503 OP2 DG E 6 -27.368 5.176 164.706 1.00 16.43 O ANISOU 1503 OP2 DG E 6 2333 1688 2221 347 -203 -609 O ATOM 1504 O5' DG E 6 -26.805 6.163 162.473 1.00 15.99 O ANISOU 1504 O5' DG E 6 2191 1711 2172 338 -169 -643 O ATOM 1505 C5' DG E 6 -26.093 6.272 161.232 1.00 15.98 C ANISOU 1505 C5' DG E 6 2144 1746 2181 343 -158 -667 C ATOM 1506 C4' DG E 6 -26.991 6.888 160.167 1.00 10.60 C ANISOU 1506 C4' DG E 6 1449 1095 1482 316 -123 -666 C ATOM 1507 O4' DG E 6 -27.968 5.902 159.751 1.00 13.18 O ANISOU 1507 O4' DG E 6 1795 1403 1811 306 -114 -664 O ATOM 1508 C3' DG E 6 -27.805 8.110 160.620 1.00 12.45 C ANISOU 1508 C3' DG E 6 1697 1340 1694 293 -110 -646 C ATOM 1509 O3' DG E 6 -27.873 9.050 159.547 1.00 13.08 O ANISOU 1509 O3' DG E 6 1747 1461 1762 278 -86 -653 O ATOM 1510 C2' DG E 6 -29.179 7.505 160.931 1.00 13.03 C ANISOU 1510 C2' DG E 6 1805 1384 1761 277 -102 -631 C ATOM 1511 C1' DG E 6 -29.264 6.424 159.854 1.00 12.93 C ANISOU 1511 C1' DG E 6 1780 1371 1761 280 -97 -648 C ATOM 1512 N9 DG E 6 -30.172 5.322 160.198 1.00 14.15 N ANISOU 1512 N9 DG E 6 1967 1487 1922 274 -100 -641 N ATOM 1513 C8 DG E 6 -30.174 4.597 161.356 1.00 10.69 C ANISOU 1513 C8 DG E 6 1564 1006 1491 283 -118 -630 C ATOM 1514 N7 DG E 6 -31.094 3.679 161.401 1.00 11.95 N ANISOU 1514 N7 DG E 6 1748 1135 1656 272 -114 -627 N ATOM 1515 C5 DG E 6 -31.747 3.799 160.190 1.00 10.69 C ANISOU 1515 C5 DG E 6 1567 1002 1494 255 -95 -639 C ATOM 1516 C6 DG E 6 -32.838 3.067 159.682 1.00 17.46 C ANISOU 1516 C6 DG E 6 2433 1843 2356 237 -86 -644 C ATOM 1517 O6 DG E 6 -33.459 2.150 160.238 1.00 15.21 O ANISOU 1517 O6 DG E 6 2179 1517 2082 231 -90 -638 O ATOM 1518 N1 DG E 6 -33.221 3.518 158.410 1.00 12.28 N ANISOU 1518 N1 DG E 6 1749 1224 1692 225 -71 -655 N ATOM 1519 C2 DG E 6 -32.594 4.544 157.723 1.00 10.84 C ANISOU 1519 C2 DG E 6 1535 1085 1496 229 -63 -660 C ATOM 1520 N2 DG E 6 -33.085 4.844 156.509 1.00 14.19 N ANISOU 1520 N2 DG E 6 1941 1539 1912 216 -50 -669 N ATOM 1521 N3 DG E 6 -31.565 5.237 158.199 1.00 17.71 N ANISOU 1521 N3 DG E 6 2395 1969 2364 244 -68 -655 N ATOM 1522 C4 DG E 6 -31.196 4.810 159.434 1.00 11.79 C ANISOU 1522 C4 DG E 6 1671 1186 1623 257 -86 -646 C ATOM 1523 P DA E 7 -28.716 10.409 159.690 1.00 12.99 P ANISOU 1523 P DA E 7 1743 1467 1727 254 -68 -635 P ATOM 1524 OP1 DA E 7 -28.019 11.415 158.857 1.00 14.07 O ANISOU 1524 OP1 DA E 7 1845 1642 1857 250 -56 -645 O ATOM 1525 OP2 DA E 7 -29.033 10.664 161.114 1.00 11.02 O ANISOU 1525 OP2 DA E 7 1527 1189 1470 254 -81 -617 O ATOM 1526 O5' DA E 7 -30.104 10.083 158.996 1.00 14.76 O ANISOU 1526 O5' DA E 7 1976 1691 1942 235 -49 -629 O ATOM 1527 C5' DA E 7 -30.142 9.836 157.621 1.00 16.01 C ANISOU 1527 C5' DA E 7 2111 1871 2100 231 -36 -643 C ATOM 1528 C4' DA E 7 -31.565 9.789 157.118 1.00 17.82 C ANISOU 1528 C4' DA E 7 2350 2101 2319 212 -23 -636 C ATOM 1529 O4' DA E 7 -32.208 8.570 157.566 1.00 9.68 O ANISOU 1529 O4' DA E 7 1343 1034 1302 212 -32 -636 O ATOM 1530 C3' DA E 7 -32.462 10.953 157.565 1.00 13.36 C ANISOU 1530 C3' DA E 7 1795 1545 1738 196 -12 -618 C ATOM 1531 O3' DA E 7 -33.254 11.328 156.447 1.00 14.36 O ANISOU 1531 O3' DA E 7 1910 1695 1853 182 2 -621 O ATOM 1532 C2' DA E 7 -33.302 10.325 158.697 1.00 9.03 C ANISOU 1532 C2' DA E 7 1277 958 1197 193 -17 -608 C ATOM 1533 C1' DA E 7 -33.435 8.880 158.205 1.00 13.67 C ANISOU 1533 C1' DA E 7 1867 1526 1801 197 -25 -622 C ATOM 1534 N9 DA E 7 -33.656 7.914 159.283 1.00 16.55 N ANISOU 1534 N9 DA E 7 2262 1847 2180 201 -36 -617 N ATOM 1535 C8 DA E 7 -32.999 7.863 160.475 1.00 9.49 C ANISOU 1535 C8 DA E 7 1387 929 1287 215 -51 -608 C ATOM 1536 N7 DA E 7 -33.400 6.906 161.255 1.00 16.52 N ANISOU 1536 N7 DA E 7 2310 1779 2189 216 -59 -602 N ATOM 1537 C5 DA E 7 -34.383 6.263 160.523 1.00 9.72 C ANISOU 1537 C5 DA E 7 1445 913 1336 201 -49 -611 C ATOM 1538 C6 DA E 7 -35.197 5.148 160.814 1.00 9.93 C ANISOU 1538 C6 DA E 7 1496 900 1377 192 -50 -612 C ATOM 1539 N6 DA E 7 -35.130 4.474 161.976 1.00 10.11 N ANISOU 1539 N6 DA E 7 1556 880 1406 198 -61 -599 N ATOM 1540 N1 DA E 7 -36.093 4.758 159.872 1.00 15.18 N ANISOU 1540 N1 DA E 7 2149 1571 2050 175 -42 -625 N ATOM 1541 C2 DA E 7 -36.148 5.446 158.723 1.00 11.49 C ANISOU 1541 C2 DA E 7 1648 1145 1571 170 -33 -634 C ATOM 1542 N3 DA E 7 -35.424 6.508 158.344 1.00 14.20 N ANISOU 1542 N3 DA E 7 1971 1527 1899 178 -29 -631 N ATOM 1543 C4 DA E 7 -34.557 6.869 159.304 1.00 18.33 C ANISOU 1543 C4 DA E 7 2504 2043 2418 192 -37 -620 C ATOM 1544 P DA E 8 -34.342 12.505 156.509 1.00 13.19 P ANISOU 1544 P DA E 8 1765 1560 1688 166 16 -606 P ATOM 1545 OP1 DA E 8 -34.215 13.238 155.243 1.00 16.72 O ANISOU 1545 OP1 DA E 8 2192 2042 2118 161 26 -611 O ATOM 1546 OP2 DA E 8 -34.126 13.287 157.754 1.00 14.29 O ANISOU 1546 OP2 DA E 8 1919 1691 1821 168 15 -591 O ATOM 1547 O5' DA E 8 -35.726 11.739 156.715 1.00 21.71 O ANISOU 1547 O5' DA E 8 2857 2616 2777 156 16 -607 O ATOM 1548 C5' DA E 8 -36.602 11.571 155.673 1.00 23.73 C ANISOU 1548 C5' DA E 8 3102 2884 3031 146 20 -616 C ATOM 1549 C4' DA E 8 -37.580 10.432 155.938 1.00 20.93 C ANISOU 1549 C4' DA E 8 2757 2499 2696 138 15 -624 C ATOM 1550 O4' DA E 8 -37.038 9.481 156.858 1.00 16.35 O ANISOU 1550 O4' DA E 8 2196 1886 2131 147 6 -623 O ATOM 1551 C3' DA E 8 -38.898 10.830 156.563 1.00 12.07 C ANISOU 1551 C3' DA E 8 1640 1369 1577 123 25 -612 C ATOM 1552 O3' DA E 8 -39.757 11.237 155.566 1.00 14.34 O ANISOU 1552 O3' DA E 8 1909 1679 1859 113 28 -618 O ATOM 1553 C2' DA E 8 -39.394 9.523 157.145 1.00 21.98 C ANISOU 1553 C2' DA E 8 2911 2586 2855 116 21 -611 C ATOM 1554 C1' DA E 8 -38.120 8.747 157.399 1.00 17.00 C ANISOU 1554 C1' DA E 8 2293 1937 2231 135 7 -624 C ATOM 1555 N9 DA E 8 -37.864 8.494 158.797 1.00 13.86 N ANISOU 1555 N9 DA E 8 1921 1508 1836 139 6 -603 N ATOM 1556 C8 DA E 8 -36.975 9.141 159.599 1.00 10.25 C ANISOU 1556 C8 DA E 8 1473 1053 1367 152 4 -590 C ATOM 1557 N7 DA E 8 -36.921 8.645 160.812 1.00 13.70 N ANISOU 1557 N7 DA E 8 1940 1456 1809 154 0 -573 N ATOM 1558 C5 DA E 8 -37.825 7.605 160.795 1.00 9.41 C ANISOU 1558 C5 DA E 8 1406 887 1282 140 3 -574 C ATOM 1559 C6 DA E 8 -38.235 6.687 161.784 1.00 17.08 C ANISOU 1559 C6 DA E 8 2409 1816 2264 133 3 -559 C ATOM 1560 N6 DA E 8 -37.746 6.674 163.020 1.00 9.67 N ANISOU 1560 N6 DA E 8 1502 855 1317 143 -2 -539 N ATOM 1561 N1 DA E 8 -39.162 5.776 161.443 1.00 16.07 N ANISOU 1561 N1 DA E 8 2282 1671 2154 116 7 -564 N ATOM 1562 C2 DA E 8 -39.647 5.790 160.202 1.00 15.43 C ANISOU 1562 C2 DA E 8 2171 1612 2079 107 8 -585 C ATOM 1563 N3 DA E 8 -39.344 6.607 159.196 1.00 15.21 N ANISOU 1563 N3 DA E 8 2114 1624 2040 114 7 -601 N ATOM 1564 C4 DA E 8 -38.427 7.506 159.569 1.00 14.73 C ANISOU 1564 C4 DA E 8 2054 1580 1962 130 6 -593 C ATOM 1565 P DT E 9 -40.953 12.231 155.906 1.00 13.22 P ANISOU 1565 P DT E 9 1762 1549 1712 101 42 -594 P ATOM 1566 OP1 DT E 9 -41.289 12.834 154.599 1.00 14.74 O ANISOU 1566 OP1 DT E 9 1936 1773 1892 99 38 -606 O ATOM 1567 OP2 DT E 9 -40.566 13.104 157.055 1.00 11.32 O ANISOU 1567 OP2 DT E 9 1536 1305 1461 107 53 -569 O ATOM 1568 O5' DT E 9 -42.136 11.278 156.412 1.00 17.78 O ANISOU 1568 O5' DT E 9 2342 2099 2315 84 44 -588 O ATOM 1569 C5' DT E 9 -42.715 10.302 155.533 1.00 16.31 C ANISOU 1569 C5' DT E 9 2144 1907 2145 74 32 -610 C ATOM 1570 C4' DT E 9 -43.502 9.285 156.337 1.00 15.85 C ANISOU 1570 C4' DT E 9 2096 1814 2113 57 37 -601 C ATOM 1571 O4' DT E 9 -42.592 8.615 157.220 1.00 16.24 O ANISOU 1571 O4' DT E 9 2171 1834 2165 66 36 -597 O ATOM 1572 C3' DT E 9 -44.535 9.882 157.274 1.00 17.25 C ANISOU 1572 C3' DT E 9 2270 1988 2296 45 58 -573 C ATOM 1573 O3' DT E 9 -45.770 10.040 156.621 1.00 17.07 O ANISOU 1573 O3' DT E 9 2220 1980 2286 30 57 -576 O ATOM 1574 C2' DT E 9 -44.654 8.830 158.367 1.00 16.35 C ANISOU 1574 C2' DT E 9 2179 1833 2200 35 65 -562 C ATOM 1575 C1' DT E 9 -43.278 8.197 158.382 1.00 18.41 C ANISOU 1575 C1' DT E 9 2462 2079 2455 53 49 -575 C ATOM 1576 N1 DT E 9 -42.465 8.518 159.583 1.00 17.66 N ANISOU 1576 N1 DT E 9 2394 1970 2345 66 56 -555 N ATOM 1577 C2 DT E 9 -42.523 7.654 160.639 1.00 18.94 C ANISOU 1577 C2 DT E 9 2585 2093 2518 61 60 -541 C ATOM 1578 O2 DT E 9 -43.215 6.662 160.642 1.00 25.66 O ANISOU 1578 O2 DT E 9 3440 2920 3391 44 61 -544 O ATOM 1579 N3 DT E 9 -41.736 7.974 161.688 1.00 12.69 N ANISOU 1579 N3 DT E 9 1821 1290 1711 75 61 -525 N ATOM 1580 C4 DT E 9 -40.902 9.057 161.807 1.00 13.51 C ANISOU 1580 C4 DT E 9 1923 1417 1793 92 59 -521 C ATOM 1581 O4 DT E 9 -40.209 9.230 162.799 1.00 13.15 O ANISOU 1581 O4 DT E 9 1904 1357 1735 103 56 -507 O ATOM 1582 C5 DT E 9 -40.879 9.947 160.675 1.00 9.07 C ANISOU 1582 C5 DT E 9 1329 895 1223 95 57 -535 C ATOM 1583 C7 DT E 9 -40.007 11.174 160.710 1.00 8.84 C ANISOU 1583 C7 DT E 9 1297 891 1170 110 55 -531 C ATOM 1584 C6 DT E 9 -41.662 9.641 159.616 1.00 15.99 C ANISOU 1584 C6 DT E 9 2181 1783 2111 83 56 -550 C ATOM 1585 P DA E 10 -46.937 10.879 157.333 1.00 21.76 P ANISOU 1585 P DA E 10 2801 2582 2886 21 81 -550 P ATOM 1586 OP1 DA E 10 -47.938 11.115 156.272 1.00 24.62 O ANISOU 1586 OP1 DA E 10 3130 2968 3259 12 70 -562 O ATOM 1587 OP2 DA E 10 -46.372 12.032 158.094 1.00 19.17 O ANISOU 1587 OP2 DA E 10 2488 2263 2534 37 95 -530 O ATOM 1588 O5' DA E 10 -47.502 9.913 158.479 1.00 26.05 O ANISOU 1588 O5' DA E 10 3358 3087 3454 2 98 -536 O ATOM 1589 C5' DA E 10 -48.163 8.694 158.165 1.00 20.67 C ANISOU 1589 C5' DA E 10 2667 2384 2801 -20 90 -548 C ATOM 1590 C4' DA E 10 -48.721 8.081 159.446 1.00 15.91 C ANISOU 1590 C4' DA E 10 2081 1748 2216 -37 116 -526 C ATOM 1591 O4' DA E 10 -47.631 7.822 160.365 1.00 14.65 O ANISOU 1591 O4' DA E 10 1963 1563 2039 -24 119 -516 O ATOM 1592 C3' DA E 10 -49.692 8.959 160.194 1.00 20.92 C ANISOU 1592 C3' DA E 10 2702 2392 2854 -43 146 -502 C ATOM 1593 O3' DA E 10 -50.734 8.179 160.763 1.00 21.97 O ANISOU 1593 O3' DA E 10 2829 2501 3017 -71 166 -492 O ATOM 1594 C2' DA E 10 -48.831 9.613 161.274 1.00 13.68 C ANISOU 1594 C2' DA E 10 1821 1469 1907 -24 161 -481 C ATOM 1595 C1' DA E 10 -47.815 8.520 161.574 1.00 15.09 C ANISOU 1595 C1' DA E 10 2035 1616 2084 -21 147 -487 C ATOM 1596 N9 DA E 10 -46.516 9.058 162.021 1.00 17.11 N ANISOU 1596 N9 DA E 10 2320 1873 2309 5 140 -482 N ATOM 1597 C8 DA E 10 -45.749 10.002 161.377 1.00 19.69 C ANISOU 1597 C8 DA E 10 2637 2231 2615 25 125 -492 C ATOM 1598 N7 DA E 10 -44.640 10.320 162.019 1.00 17.25 N ANISOU 1598 N7 DA E 10 2355 1915 2283 43 121 -484 N ATOM 1599 C5 DA E 10 -44.686 9.544 163.168 1.00 12.56 C ANISOU 1599 C5 DA E 10 1794 1284 1694 36 131 -468 C ATOM 1600 C6 DA E 10 -43.805 9.414 164.264 1.00 17.53 C ANISOU 1600 C6 DA E 10 2465 1889 2307 48 129 -454 C ATOM 1601 N6 DA E 10 -42.660 10.107 164.385 1.00 12.67 N ANISOU 1601 N6 DA E 10 1859 1285 1670 70 114 -456 N ATOM 1602 N1 DA E 10 -44.152 8.542 165.247 1.00 17.77 N ANISOU 1602 N1 DA E 10 2526 1881 2345 37 141 -438 N ATOM 1603 C2 DA E 10 -45.295 7.858 165.119 1.00 15.84 C ANISOU 1603 C2 DA E 10 2269 1625 2125 12 157 -437 C ATOM 1604 N3 DA E 10 -46.199 7.902 164.133 1.00 15.39 N ANISOU 1604 N3 DA E 10 2170 1589 2088 -3 160 -450 N ATOM 1605 C4 DA E 10 -45.834 8.758 163.183 1.00 15.13 C ANISOU 1605 C4 DA E 10 2110 1593 2046 12 145 -466 C ATOM 1606 P DG E 11 -52.000 8.931 161.408 1.00 25.85 P ANISOU 1606 P DG E 11 3296 3005 3522 -82 202 -470 P ATOM 1607 OP1 DG E 11 -53.091 7.928 161.413 1.00 35.81 O ANISOU 1607 OP1 DG E 11 4536 4247 4824 -115 211 -472 O ATOM 1608 OP2 DG E 11 -52.196 10.236 160.748 1.00 28.54 O ANISOU 1608 OP2 DG E 11 3608 3386 3850 -63 195 -474 O ATOM 1609 O5' DG E 11 -51.569 9.234 162.910 1.00 22.29 O ANISOU 1609 O5' DG E 11 2888 2533 3048 -73 233 -441 O ATOM 1610 C5' DG E 11 -51.250 8.149 163.770 1.00 28.09 C ANISOU 1610 C5' DG E 11 3661 3225 3785 -85 242 -432 C ATOM 1611 C4' DG E 11 -50.632 8.642 165.053 1.00 27.21 C ANISOU 1611 C4' DG E 11 3596 3101 3643 -69 263 -407 C ATOM 1612 O4' DG E 11 -49.289 9.145 164.791 1.00 23.58 O ANISOU 1612 O4' DG E 11 3155 2652 3152 -41 235 -416 O ATOM 1613 C3' DG E 11 -51.379 9.802 165.743 1.00 27.87 C ANISOU 1613 C3' DG E 11 3670 3202 3717 -65 299 -387 C ATOM 1614 O3' DG E 11 -51.488 9.528 167.123 1.00 30.53 O ANISOU 1614 O3' DG E 11 4048 3509 4044 -72 332 -362 O ATOM 1615 C2' DG E 11 -50.431 10.981 165.527 1.00 25.21 C ANISOU 1615 C2' DG E 11 3341 2890 3346 -34 281 -391 C ATOM 1616 C1' DG E 11 -49.123 10.238 165.638 1.00 16.70 C ANISOU 1616 C1' DG E 11 2302 1790 2254 -25 254 -397 C ATOM 1617 N9 DG E 11 -47.930 11.026 165.308 1.00 17.91 N ANISOU 1617 N9 DG E 11 2465 1962 2379 2 229 -405 N ATOM 1618 C8 DG E 11 -47.745 11.921 164.269 1.00 11.06 C ANISOU 1618 C8 DG E 11 1566 1130 1505 15 212 -420 C ATOM 1619 N7 DG E 11 -46.563 12.501 164.304 1.00 14.92 N ANISOU 1619 N7 DG E 11 2074 1626 1968 35 196 -423 N ATOM 1620 C5 DG E 11 -45.959 11.973 165.454 1.00 16.08 C ANISOU 1620 C5 DG E 11 2266 1741 2103 38 199 -409 C ATOM 1621 C6 DG E 11 -44.694 12.215 166.031 1.00 13.79 C ANISOU 1621 C6 DG E 11 2009 1442 1788 56 183 -406 C ATOM 1622 O6 DG E 11 -43.802 12.978 165.635 1.00 16.14 O ANISOU 1622 O6 DG E 11 2303 1761 2070 72 165 -414 O ATOM 1623 N1 DG E 11 -44.500 11.463 167.199 1.00 15.25 N ANISOU 1623 N1 DG E 11 2237 1590 1968 53 190 -390 N ATOM 1624 C2 DG E 11 -45.415 10.595 167.731 1.00 16.23 C ANISOU 1624 C2 DG E 11 2371 1687 2107 33 212 -378 C ATOM 1625 N2 DG E 11 -45.068 9.945 168.860 1.00 10.16 N ANISOU 1625 N2 DG E 11 1651 881 1327 33 216 -362 N ATOM 1626 N3 DG E 11 -46.580 10.356 167.193 1.00 15.58 N ANISOU 1626 N3 DG E 11 2255 1613 2051 14 229 -382 N ATOM 1627 C4 DG E 11 -46.792 11.077 166.070 1.00 16.11 C ANISOU 1627 C4 DG E 11 2279 1717 2124 18 220 -398 C ATOM 1628 P DG E 12 -52.726 10.086 167.974 1.00 38.11 P ANISOU 1628 P DG E 12 4997 4472 5011 -84 384 -340 P ATOM 1629 OP1 DG E 12 -53.805 9.108 167.771 1.00 38.38 O ANISOU 1629 OP1 DG E 12 5002 4494 5087 -118 400 -342 O ATOM 1630 OP2 DG E 12 -52.959 11.507 167.659 1.00 35.73 O ANISOU 1630 OP2 DG E 12 4669 4209 4700 -62 388 -342 O ATOM 1631 O5' DG E 12 -52.197 10.026 169.486 1.00 34.11 O ANISOU 1631 O5' DG E 12 4557 3934 4471 -78 409 -315 O ATOM 1632 C5' DG E 12 -51.596 8.831 169.988 1.00 33.97 C ANISOU 1632 C5' DG E 12 4585 3876 4448 -87 399 -309 C ATOM 1633 C4' DG E 12 -50.521 9.156 171.015 1.00 31.49 C ANISOU 1633 C4' DG E 12 4333 3544 4089 -65 395 -294 C ATOM 1634 O4' DG E 12 -49.355 9.696 170.332 1.00 35.26 O ANISOU 1634 O4' DG E 12 4807 4041 4550 -38 350 -312 O ATOM 1635 C3' DG E 12 -50.922 10.199 172.067 1.00 34.45 C ANISOU 1635 C3' DG E 12 4728 3924 4437 -56 435 -273 C ATOM 1636 O3' DG E 12 -50.468 9.827 173.349 1.00 40.93 O ANISOU 1636 O3' DG E 12 5616 4708 5226 -54 447 -251 O ATOM 1637 C2' DG E 12 -50.197 11.437 171.605 1.00 35.28 C ANISOU 1637 C2' DG E 12 4823 4061 4520 -26 409 -284 C ATOM 1638 C1' DG E 12 -48.931 10.850 171.001 1.00 28.17 C ANISOU 1638 C1' DG E 12 3933 3155 3617 -16 358 -301 C ATOM 1639 N9 DG E 12 -48.332 11.784 170.050 1.00 20.78 N ANISOU 1639 N9 DG E 12 2967 2254 2675 4 328 -320 N ATOM 1640 C8 DG E 12 -48.872 12.212 168.861 1.00 22.44 C ANISOU 1640 C8 DG E 12 3121 2497 2907 2 321 -337 C ATOM 1641 N7 DG E 12 -48.142 13.110 168.256 1.00 20.43 N ANISOU 1641 N7 DG E 12 2857 2269 2638 23 297 -348 N ATOM 1642 C5 DG E 12 -47.064 13.297 169.104 1.00 14.81 C ANISOU 1642 C5 DG E 12 2192 1540 1894 38 286 -339 C ATOM 1643 C6 DG E 12 -45.953 14.146 168.977 1.00 15.03 C ANISOU 1643 C6 DG E 12 2230 1582 1897 59 261 -346 C ATOM 1644 O6 DG E 12 -45.704 14.945 168.063 1.00 9.21 O ANISOU 1644 O6 DG E 12 1465 876 1159 68 246 -359 O ATOM 1645 N1 DG E 12 -45.092 14.043 170.068 1.00 15.50 N ANISOU 1645 N1 DG E 12 2342 1617 1930 69 254 -334 N ATOM 1646 C2 DG E 12 -45.282 13.218 171.141 1.00 16.27 C ANISOU 1646 C2 DG E 12 2480 1679 2022 60 269 -317 C ATOM 1647 N2 DG E 12 -44.343 13.258 172.089 1.00 15.74 N ANISOU 1647 N2 DG E 12 2463 1590 1926 73 254 -307 N ATOM 1648 N3 DG E 12 -46.322 12.408 171.277 1.00 20.07 N ANISOU 1648 N3 DG E 12 2956 2145 2525 39 296 -309 N ATOM 1649 C4 DG E 12 -47.171 12.498 170.218 1.00 19.32 C ANISOU 1649 C4 DG E 12 2805 2075 2459 28 303 -322 C ATOM 1650 P DT E 13 -50.901 10.687 174.641 1.00 42.67 P ANISOU 1650 P DT E 13 5873 4925 5414 -48 494 -227 P ATOM 1651 OP1 DT E 13 -51.175 9.665 175.680 1.00 54.72 O ANISOU 1651 OP1 DT E 13 7449 6409 6934 -68 523 -205 O ATOM 1652 OP2 DT E 13 -51.895 11.742 174.298 1.00 32.59 O ANISOU 1652 OP2 DT E 13 4546 3684 4151 -46 524 -231 O ATOM 1653 O5' DT E 13 -49.578 11.448 175.068 1.00 29.67 O ANISOU 1653 O5' DT E 13 4271 3279 3723 -16 461 -227 O ATOM 1654 C5' DT E 13 -48.399 10.727 175.248 1.00 31.80 C ANISOU 1654 C5' DT E 13 4581 3523 3978 -7 421 -229 C ATOM 1655 C4' DT E 13 -47.317 11.628 175.801 1.00 35.02 C ANISOU 1655 C4' DT E 13 5028 3935 4344 21 396 -227 C ATOM 1656 O4' DT E 13 -46.810 12.515 174.760 1.00 31.74 O ANISOU 1656 O4' DT E 13 4568 3557 3936 37 366 -249 O ATOM 1657 C3' DT E 13 -47.754 12.531 176.945 1.00 37.54 C ANISOU 1657 C3' DT E 13 5384 4250 4628 27 436 -208 C ATOM 1658 O3' DT E 13 -46.680 12.583 177.884 1.00 35.19 O ANISOU 1658 O3' DT E 13 5153 3930 4289 44 411 -199 O ATOM 1659 C2' DT E 13 -48.007 13.880 176.238 1.00 27.39 C ANISOU 1659 C2' DT E 13 4051 3007 3348 39 438 -221 C ATOM 1660 C1' DT E 13 -46.911 13.863 175.178 1.00 23.64 C ANISOU 1660 C1' DT E 13 3550 2549 2884 51 382 -244 C ATOM 1661 N1 DT E 13 -47.173 14.683 173.945 1.00 17.73 N ANISOU 1661 N1 DT E 13 2738 1841 2157 56 374 -263 N ATOM 1662 C2 DT E 13 -46.224 15.596 173.536 1.00 16.02 C ANISOU 1662 C2 DT E 13 2517 1644 1924 75 341 -275 C ATOM 1663 O2 DT E 13 -45.205 15.840 174.169 1.00 19.06 O ANISOU 1663 O2 DT E 13 2944 2017 2280 89 318 -271 O ATOM 1664 N3 DT E 13 -46.527 16.256 172.383 1.00 11.69 N ANISOU 1664 N3 DT E 13 1915 1130 1395 78 336 -290 N ATOM 1665 C4 DT E 13 -47.634 16.067 171.586 1.00 13.07 C ANISOU 1665 C4 DT E 13 2040 1322 1603 64 354 -296 C ATOM 1666 O4 DT E 13 -47.808 16.695 170.547 1.00 17.17 O ANISOU 1666 O4 DT E 13 2517 1873 2136 69 343 -309 O ATOM 1667 C5 DT E 13 -48.581 15.091 172.060 1.00 16.64 C ANISOU 1667 C5 DT E 13 2495 1754 2074 44 386 -284 C ATOM 1668 C7 DT E 13 -49.828 14.827 171.278 1.00 18.09 C ANISOU 1668 C7 DT E 13 2623 1954 2298 27 405 -291 C ATOM 1669 C6 DT E 13 -48.302 14.435 173.193 1.00 13.72 C ANISOU 1669 C6 DT E 13 2178 1349 1685 39 396 -268 C ATOM 1670 P DT E 14 -46.771 13.463 179.218 1.00 38.00 P ANISOU 1670 P DT E 14 5568 4275 4597 55 439 -180 P ATOM 1671 OP1 DT E 14 -46.008 12.698 180.236 1.00 38.14 O ANISOU 1671 OP1 DT E 14 5658 4251 4583 59 419 -165 O ATOM 1672 OP2 DT E 14 -48.181 13.873 179.423 1.00 33.76 O ANISOU 1672 OP2 DT E 14 5011 3749 4069 42 502 -170 O ATOM 1673 O5' DT E 14 -45.876 14.741 178.875 1.00 36.19 O ANISOU 1673 O5' DT E 14 5328 4072 4350 80 403 -195 O ATOM 1674 C5' DT E 14 -44.493 14.565 178.671 1.00 34.98 C ANISOU 1674 C5' DT E 14 5187 3915 4191 94 344 -206 C ATOM 1675 C4' DT E 14 -43.795 15.897 178.484 1.00 31.34 C ANISOU 1675 C4' DT E 14 4718 3477 3711 113 320 -218 C ATOM 1676 O4' DT E 14 -44.239 16.525 177.252 1.00 25.85 O ANISOU 1676 O4' DT E 14 3954 2820 3046 111 326 -235 O ATOM 1677 C3' DT E 14 -44.015 16.924 179.593 1.00 25.73 C ANISOU 1677 C3' DT E 14 4057 2761 2959 122 345 -205 C ATOM 1678 O3' DT E 14 -42.767 17.524 179.854 1.00 24.52 O ANISOU 1678 O3' DT E 14 3930 2606 2780 139 299 -212 O ATOM 1679 C2' DT E 14 -45.021 17.909 178.966 1.00 27.11 C ANISOU 1679 C2' DT E 14 4182 2967 3150 120 381 -211 C ATOM 1680 C1' DT E 14 -44.602 17.864 177.500 1.00 22.05 C ANISOU 1680 C1' DT E 14 3477 2356 2547 120 347 -233 C ATOM 1681 N1 DT E 14 -45.653 18.215 176.497 1.00 18.87 N ANISOU 1681 N1 DT E 14 3010 1982 2177 112 374 -241 N ATOM 1682 C2 DT E 14 -45.301 19.014 175.425 1.00 15.68 C ANISOU 1682 C2 DT E 14 2563 1610 1785 120 350 -258 C ATOM 1683 O2 DT E 14 -44.195 19.503 175.292 1.00 16.47 O ANISOU 1683 O2 DT E 14 2672 1714 1870 131 312 -267 O ATOM 1684 N3 DT E 14 -46.299 19.255 174.532 1.00 12.07 N ANISOU 1684 N3 DT E 14 2052 1178 1358 114 371 -264 N ATOM 1685 C4 DT E 14 -47.571 18.746 174.553 1.00 10.28 C ANISOU 1685 C4 DT E 14 1802 949 1153 100 411 -257 C ATOM 1686 O4 DT E 14 -48.380 19.002 173.678 1.00 16.10 O ANISOU 1686 O4 DT E 14 2487 1711 1919 97 422 -265 O ATOM 1687 C5 DT E 14 -47.880 17.884 175.677 1.00 21.33 C ANISOU 1687 C5 DT E 14 3245 2316 2542 90 438 -240 C ATOM 1688 C7 DT E 14 -49.252 17.295 175.813 1.00 23.58 C ANISOU 1688 C7 DT E 14 3509 2597 2852 71 486 -230 C ATOM 1689 C6 DT E 14 -46.910 17.651 176.584 1.00 18.42 C ANISOU 1689 C6 DT E 14 2937 1922 2141 96 418 -232 C ATOM 1690 P DA E 15 -42.544 18.490 181.098 1.00 32.53 P ANISOU 1690 P DA E 15 5010 3607 3744 152 304 -202 P ATOM 1691 OP1 DA E 15 -41.160 18.262 181.572 1.00 34.39 O ANISOU 1691 OP1 DA E 15 5285 3823 3958 163 247 -205 O ATOM 1692 OP2 DA E 15 -43.715 18.393 182.003 1.00 33.63 O ANISOU 1692 OP2 DA E 15 5186 3729 3864 144 363 -183 O ATOM 1693 O5' DA E 15 -42.589 19.933 180.437 1.00 31.16 O ANISOU 1693 O5' DA E 15 4799 3466 3574 159 305 -217 O ATOM 1694 C5' DA E 15 -41.631 20.290 179.469 1.00 26.92 C ANISOU 1694 C5' DA E 15 4221 2951 3056 164 259 -236 C ATOM 1695 C4' DA E 15 -42.042 21.568 178.778 1.00 23.21 C ANISOU 1695 C4' DA E 15 3713 2511 2593 167 274 -245 C ATOM 1696 O4' DA E 15 -43.269 21.340 178.035 1.00 23.23 O ANISOU 1696 O4' DA E 15 3667 2531 2628 158 314 -245 O ATOM 1697 C3' DA E 15 -42.341 22.747 179.710 1.00 21.92 C ANISOU 1697 C3' DA E 15 3596 2340 2392 177 297 -238 C ATOM 1698 O3' DA E 15 -41.841 23.902 179.124 1.00 25.83 O ANISOU 1698 O3' DA E 15 4067 2857 2890 182 274 -249 O ATOM 1699 C2' DA E 15 -43.876 22.766 179.747 1.00 23.07 C ANISOU 1699 C2' DA E 15 3727 2491 2548 173 358 -228 C ATOM 1700 C1' DA E 15 -44.157 22.403 178.310 1.00 20.87 C ANISOU 1700 C1' DA E 15 3372 2240 2317 164 353 -240 C ATOM 1701 N9 DA E 15 -45.519 21.970 178.017 1.00 19.60 N ANISOU 1701 N9 DA E 15 3178 2088 2183 154 400 -234 N ATOM 1702 C8 DA E 15 -46.335 21.183 178.775 1.00 18.70 C ANISOU 1702 C8 DA E 15 3085 1953 2066 145 439 -219 C ATOM 1703 N7 DA E 15 -47.502 20.946 178.215 1.00 21.09 N ANISOU 1703 N7 DA E 15 3339 2271 2402 135 475 -219 N ATOM 1704 C5 DA E 15 -47.429 21.613 177.000 1.00 19.00 C ANISOU 1704 C5 DA E 15 3020 2037 2161 140 454 -235 C ATOM 1705 C6 DA E 15 -48.341 21.758 175.919 1.00 14.31 C ANISOU 1705 C6 DA E 15 2360 1471 1606 136 468 -243 C ATOM 1706 N6 DA E 15 -49.566 21.217 175.890 1.00 12.90 N ANISOU 1706 N6 DA E 15 2153 1295 1454 124 508 -237 N ATOM 1707 N1 DA E 15 -47.946 22.487 174.875 1.00 11.96 N ANISOU 1707 N1 DA E 15 2028 1199 1318 145 438 -258 N ATOM 1708 C2 DA E 15 -46.730 23.036 174.889 1.00 10.85 C ANISOU 1708 C2 DA E 15 1913 1057 1154 154 400 -264 C ATOM 1709 N3 DA E 15 -45.788 22.976 175.830 1.00 13.58 N ANISOU 1709 N3 DA E 15 2313 1379 1467 158 382 -259 N ATOM 1710 C4 DA E 15 -46.212 22.241 176.869 1.00 19.47 C ANISOU 1710 C4 DA E 15 3096 2099 2201 152 410 -244 C ATOM 1711 P DG E 16 -41.423 25.174 180.001 1.00 34.73 P ANISOU 1711 P DG E 16 5228 3983 3986 188 260 -239 P ATOM 1712 OP1 DG E 16 -40.011 25.012 180.374 1.00 37.40 O ANISOU 1712 OP1 DG E 16 5591 4310 4311 189 205 -243 O ATOM 1713 OP2 DG E 16 -42.458 25.393 181.030 1.00 32.24 O ANISOU 1713 OP2 DG E 16 4951 3652 3646 192 307 -222 O ATOM 1714 O5' DG E 16 -41.555 26.395 178.972 1.00 40.18 O ANISOU 1714 O5' DG E 16 5868 4704 4696 189 258 -248 O ATOM 1715 C5' DG E 16 -40.831 26.378 177.756 1.00 34.93 C ANISOU 1715 C5' DG E 16 5156 4060 4057 185 226 -265 C ATOM 1716 C4' DG E 16 -41.541 27.186 176.680 1.00 22.96 C ANISOU 1716 C4' DG E 16 3592 2571 2562 185 246 -271 C ATOM 1717 O4' DG E 16 -42.807 26.552 176.322 1.00 17.16 O ANISOU 1717 O4' DG E 16 2835 1839 1845 186 288 -271 O ATOM 1718 C3' DG E 16 -41.883 28.629 177.048 1.00 22.76 C ANISOU 1718 C3' DG E 16 3578 2549 2522 191 256 -262 C ATOM 1719 O3' DG E 16 -41.728 29.435 175.874 1.00 29.84 O ANISOU 1719 O3' DG E 16 4433 3469 3436 190 245 -272 O ATOM 1720 C2' DG E 16 -43.353 28.521 177.487 1.00 15.39 C ANISOU 1720 C2' DG E 16 2650 1611 1588 198 309 -251 C ATOM 1721 C1' DG E 16 -43.866 27.489 176.492 1.00 17.08 C ANISOU 1721 C1' DG E 16 2822 1836 1832 193 323 -262 C ATOM 1722 N9 DG E 16 -45.060 26.759 176.920 1.00 16.32 N ANISOU 1722 N9 DG E 16 2731 1730 1741 194 372 -255 N ATOM 1723 C8 DG E 16 -45.235 26.024 178.069 1.00 14.57 C ANISOU 1723 C8 DG E 16 2555 1482 1499 191 392 -244 C ATOM 1724 N7 DG E 16 -46.407 25.446 178.137 1.00 15.90 N ANISOU 1724 N7 DG E 16 2714 1647 1680 189 440 -240 N ATOM 1725 C5 DG E 16 -47.028 25.808 176.945 1.00 13.64 C ANISOU 1725 C5 DG E 16 2364 1389 1428 190 446 -249 C ATOM 1726 C6 DG E 16 -48.312 25.483 176.436 1.00 10.32 C ANISOU 1726 C6 DG E 16 1895 983 1041 186 482 -248 C ATOM 1727 O6 DG E 16 -49.202 24.786 176.959 1.00 16.82 O ANISOU 1727 O6 DG E 16 2718 1798 1874 178 521 -238 O ATOM 1728 N1 DG E 16 -48.525 26.056 175.186 1.00 13.57 N ANISOU 1728 N1 DG E 16 2253 1424 1480 190 468 -259 N ATOM 1729 C2 DG E 16 -47.611 26.842 174.514 1.00 11.96 C ANISOU 1729 C2 DG E 16 2046 1231 1268 197 428 -269 C ATOM 1730 N2 DG E 16 -47.989 27.326 173.318 1.00 12.96 N ANISOU 1730 N2 DG E 16 2122 1383 1419 201 420 -278 N ATOM 1731 N3 DG E 16 -46.426 27.155 174.986 1.00 15.66 N ANISOU 1731 N3 DG E 16 2557 1686 1707 199 399 -271 N ATOM 1732 C4 DG E 16 -46.200 26.605 176.194 1.00 11.13 C ANISOU 1732 C4 DG E 16 2032 1087 1110 195 406 -260 C ATOM 1733 P DT E 17 -42.307 30.937 175.770 1.00 27.95 P ANISOU 1733 P DT E 17 4190 3237 3191 198 259 -266 P ATOM 1734 OP1 DT E 17 -41.441 31.608 174.782 1.00 32.32 O ANISOU 1734 OP1 DT E 17 4720 3805 3754 192 228 -277 O ATOM 1735 OP2 DT E 17 -42.432 31.512 177.124 1.00 27.29 O ANISOU 1735 OP2 DT E 17 4156 3132 3079 204 268 -253 O ATOM 1736 O5' DT E 17 -43.755 30.782 175.101 1.00 33.95 O ANISOU 1736 O5' DT E 17 4915 4011 3973 206 300 -267 O ATOM 1737 C5' DT E 17 -43.876 30.214 173.801 1.00 32.31 C ANISOU 1737 C5' DT E 17 4662 3823 3793 202 296 -280 C ATOM 1738 C4' DT E 17 -44.896 30.954 172.954 1.00 30.78 C ANISOU 1738 C4' DT E 17 4435 3647 3614 213 317 -282 C ATOM 1739 O4' DT E 17 -46.218 30.413 173.192 1.00 28.45 O ANISOU 1739 O4' DT E 17 4128 3350 3331 220 359 -278 O ATOM 1740 C3' DT E 17 -45.021 32.448 173.222 1.00 36.02 C ANISOU 1740 C3' DT E 17 5115 4308 4264 222 317 -274 C ATOM 1741 O3' DT E 17 -45.491 33.105 172.018 1.00 35.76 O ANISOU 1741 O3' DT E 17 5048 4294 4247 230 318 -281 O ATOM 1742 C2' DT E 17 -46.065 32.495 174.355 1.00 25.11 C ANISOU 1742 C2' DT E 17 3755 2913 2873 233 356 -262 C ATOM 1743 C1' DT E 17 -46.998 31.349 173.957 1.00 26.43 C ANISOU 1743 C1' DT E 17 3891 3088 3065 233 385 -267 C ATOM 1744 N1 DT E 17 -47.630 30.595 175.114 1.00 17.40 N ANISOU 1744 N1 DT E 17 2771 1928 1914 232 421 -257 N ATOM 1745 C2 DT E 17 -48.881 30.080 174.932 1.00 24.72 C ANISOU 1745 C2 DT E 17 3669 2861 2863 236 462 -258 C ATOM 1746 O2 DT E 17 -49.521 30.258 173.902 1.00 18.73 O ANISOU 1746 O2 DT E 17 2866 2121 2130 243 468 -267 O ATOM 1747 N3 DT E 17 -49.374 29.363 176.002 1.00 19.63 N ANISOU 1747 N3 DT E 17 3051 2199 2211 232 497 -248 N ATOM 1748 C4 DT E 17 -48.726 29.106 177.198 1.00 15.22 C ANISOU 1748 C4 DT E 17 2546 1616 1619 226 491 -237 C ATOM 1749 O4 DT E 17 -49.244 28.456 178.103 1.00 22.86 O ANISOU 1749 O4 DT E 17 3540 2568 2579 223 526 -228 O ATOM 1750 C5 DT E 17 -47.407 29.651 177.311 1.00 13.17 C ANISOU 1750 C5 DT E 17 2314 1352 1339 224 443 -238 C ATOM 1751 C7 DT E 17 -46.626 29.436 178.567 1.00 11.36 C ANISOU 1751 C7 DT E 17 2144 1097 1075 219 429 -228 C ATOM 1752 C6 DT E 17 -46.917 30.362 176.273 1.00 15.12 C ANISOU 1752 C6 DT E 17 2532 1617 1597 226 411 -248 C ATOM 1753 P DG E 18 -45.672 34.707 171.970 1.00 44.69 P ANISOU 1753 P DG E 18 6191 5423 5367 242 317 -275 P ATOM 1754 OP1 DG E 18 -45.464 35.114 170.558 1.00 48.96 O ANISOU 1754 OP1 DG E 18 6704 5981 5918 242 300 -284 O ATOM 1755 OP2 DG E 18 -44.896 35.316 173.086 1.00 38.71 O ANISOU 1755 OP2 DG E 18 5479 4645 4584 237 303 -267 O ATOM 1756 O5' DG E 18 -47.217 34.912 172.280 1.00 38.15 O ANISOU 1756 O5' DG E 18 5352 4595 4548 262 358 -269 O ATOM 1757 C5' DG E 18 -48.176 34.376 171.395 1.00 34.12 C ANISOU 1757 C5' DG E 18 4799 4101 4063 270 377 -277 C ATOM 1758 C4' DG E 18 -49.546 34.469 172.007 1.00 35.86 C ANISOU 1758 C4' DG E 18 5013 4320 4293 286 419 -271 C ATOM 1759 O4' DG E 18 -49.626 33.577 173.157 1.00 38.56 O ANISOU 1759 O4' DG E 18 5375 4648 4627 277 440 -264 O ATOM 1760 C3' DG E 18 -49.917 35.864 172.551 1.00 29.70 C ANISOU 1760 C3' DG E 18 4255 3529 3499 304 427 -262 C ATOM 1761 O3' DG E 18 -51.281 36.089 172.299 1.00 27.07 O ANISOU 1761 O3' DG E 18 3892 3206 3188 325 458 -264 O ATOM 1762 C2' DG E 18 -49.661 35.705 174.041 1.00 29.09 C ANISOU 1762 C2' DG E 18 4222 3432 3399 297 438 -252 C ATOM 1763 C1' DG E 18 -50.218 34.305 174.194 1.00 33.64 C ANISOU 1763 C1' DG E 18 4778 4012 3991 290 465 -253 C ATOM 1764 N9 DG E 18 -49.998 33.654 175.481 1.00 21.30 N ANISOU 1764 N9 DG E 18 3254 2431 2410 279 479 -244 N ATOM 1765 C8 DG E 18 -48.938 33.798 176.351 1.00 19.77 C ANISOU 1765 C8 DG E 18 3109 2219 2185 270 455 -238 C ATOM 1766 N7 DG E 18 -49.067 33.072 177.439 1.00 17.91 N ANISOU 1766 N7 DG E 18 2903 1967 1935 265 477 -229 N ATOM 1767 C5 DG E 18 -50.293 32.423 177.266 1.00 13.82 C ANISOU 1767 C5 DG E 18 2352 1458 1442 269 520 -230 C ATOM 1768 C6 DG E 18 -50.995 31.527 178.113 1.00 14.49 C ANISOU 1768 C6 DG E 18 2449 1532 1525 264 563 -222 C ATOM 1769 O6 DG E 18 -50.656 31.081 179.220 1.00 15.72 O ANISOU 1769 O6 DG E 18 2652 1666 1654 257 570 -212 O ATOM 1770 N1 DG E 18 -52.198 31.123 177.546 1.00 14.69 N ANISOU 1770 N1 DG E 18 2424 1572 1585 269 600 -227 N ATOM 1771 C2 DG E 18 -52.676 31.540 176.335 1.00 15.10 C ANISOU 1771 C2 DG E 18 2423 1647 1667 279 593 -238 C ATOM 1772 N2 DG E 18 -53.863 31.049 175.960 1.00 16.25 N ANISOU 1772 N2 DG E 18 2522 1805 1846 282 632 -241 N ATOM 1773 N3 DG E 18 -52.041 32.381 175.544 1.00 19.24 N ANISOU 1773 N3 DG E 18 2941 2180 2188 285 553 -244 N ATOM 1774 C4 DG E 18 -50.864 32.780 176.072 1.00 17.98 C ANISOU 1774 C4 DG E 18 2828 2007 1997 278 520 -240 C ATOM 1775 P DG E 19 -51.783 37.519 171.784 1.00 34.47 P ANISOU 1775 P DG E 19 4825 4145 4127 350 455 -264 P ATOM 1776 OP1 DG E 19 -51.313 37.716 170.394 1.00 37.80 O ANISOU 1776 OP1 DG E 19 5229 4580 4555 349 425 -272 O ATOM 1777 OP2 DG E 19 -51.352 38.477 172.834 1.00 31.47 O ANISOU 1777 OP2 DG E 19 4494 3744 3719 351 452 -254 O ATOM 1778 O5' DG E 19 -53.377 37.362 171.757 1.00 36.55 O ANISOU 1778 O5' DG E 19 5048 4420 4421 373 497 -265 O ATOM 1779 C5' DG E 19 -53.983 36.360 170.931 1.00 39.67 C ANISOU 1779 C5' DG E 19 5393 4834 4847 372 507 -274 C ATOM 1780 C4' DG E 19 -55.173 35.717 171.638 1.00 41.57 C ANISOU 1780 C4' DG E 19 5608 5076 5109 377 555 -272 C ATOM 1781 O4' DG E 19 -54.714 34.926 172.770 1.00 34.93 O ANISOU 1781 O4' DG E 19 4800 4222 4251 355 568 -264 O ATOM 1782 C3' DG E 19 -56.209 36.691 172.187 1.00 40.30 C ANISOU 1782 C3' DG E 19 5444 4914 4954 404 583 -267 C ATOM 1783 O3' DG E 19 -57.516 36.254 171.824 1.00 47.26 O ANISOU 1783 O3' DG E 19 6268 5813 5878 418 615 -273 O ATOM 1784 C2' DG E 19 -55.991 36.638 173.701 1.00 34.39 C ANISOU 1784 C2' DG E 19 4743 4146 4179 393 604 -257 C ATOM 1785 C1' DG E 19 -55.483 35.216 173.904 1.00 27.35 C ANISOU 1785 C1' DG E 19 3853 3252 3286 364 606 -256 C ATOM 1786 N9 DG E 19 -54.631 35.072 175.084 1.00 19.01 N ANISOU 1786 N9 DG E 19 2855 2174 2193 348 602 -246 N ATOM 1787 C8 DG E 19 -53.380 35.612 175.278 1.00 17.79 C ANISOU 1787 C8 DG E 19 2745 2006 2007 340 563 -243 C ATOM 1788 N7 DG E 19 -52.866 35.332 176.462 1.00 15.00 N ANISOU 1788 N7 DG E 19 2439 1634 1626 328 568 -234 N ATOM 1789 C5 DG E 19 -53.851 34.567 177.083 1.00 14.27 C ANISOU 1789 C5 DG E 19 2335 1541 1545 328 615 -229 C ATOM 1790 C6 DG E 19 -53.870 33.985 178.369 1.00 16.83 C ANISOU 1790 C6 DG E 19 2699 1846 1848 318 642 -219 C ATOM 1791 O6 DG E 19 -52.990 34.026 179.244 1.00 18.44 O ANISOU 1791 O6 DG E 19 2958 2031 2019 309 625 -211 O ATOM 1792 N1 DG E 19 -55.059 33.306 178.610 1.00 14.95 N ANISOU 1792 N1 DG E 19 2432 1614 1634 319 693 -216 N ATOM 1793 C2 DG E 19 -56.094 33.207 177.729 1.00 12.53 C ANISOU 1793 C2 DG E 19 2063 1330 1369 328 713 -224 C ATOM 1794 N2 DG E 19 -57.158 32.511 178.142 1.00 19.03 N ANISOU 1794 N2 DG E 19 2862 2157 2213 325 764 -221 N ATOM 1795 N3 DG E 19 -56.096 33.753 176.521 1.00 17.46 N ANISOU 1795 N3 DG E 19 2649 1972 2013 340 685 -235 N ATOM 1796 C4 DG E 19 -54.941 34.406 176.261 1.00 16.61 C ANISOU 1796 C4 DG E 19 2573 1857 1880 339 637 -237 C TER 1797 DG E 19 HETATM 1798 O HOH A 201 -20.995 4.848 181.028 1.00 44.04 O ANISOU 1798 O HOH A 201 6418 4811 5505 559 -734 -393 O HETATM 1799 O HOH A 202 -62.145 21.482 154.797 1.00 51.24 O ANISOU 1799 O HOH A 202 6057 6576 6835 112 103 -471 O HETATM 1800 O HOH A 203 -37.064 10.304 148.442 1.00 45.57 O ANISOU 1800 O HOH A 203 5829 5742 5745 137 8 -695 O HETATM 1801 O HOH A 204 -51.871 15.098 167.024 1.00 46.56 O ANISOU 1801 O HOH A 204 6034 5653 6005 10 362 -348 O HETATM 1802 O HOH A 205 -31.566 13.358 181.470 1.00 40.22 O ANISOU 1802 O HOH A 205 6040 4476 4765 269 -199 -272 O HETATM 1803 O HOH A 206 -29.194 19.855 159.464 1.00 19.96 O ANISOU 1803 O HOH A 206 2612 2485 2487 156 10 -562 O HETATM 1804 O HOH A 207 -28.011 21.863 157.910 1.00 37.32 O ANISOU 1804 O HOH A 207 4775 4735 4670 131 36 -568 O HETATM 1805 O HOH A 208 -32.425 23.476 146.228 1.00 34.27 O ANISOU 1805 O HOH A 208 4415 4509 4099 94 152 -584 O HETATM 1806 O HOH A 209 -38.589 36.793 159.711 1.00 23.23 O ANISOU 1806 O HOH A 209 3312 2861 2653 130 144 -339 O HETATM 1807 O HOH A 210 -49.416 14.843 166.828 1.00 31.29 O ANISOU 1807 O HOH A 210 4154 3706 4029 30 305 -360 O HETATM 1808 O HOH A 211 -38.799 35.042 156.426 1.00 31.39 O ANISOU 1808 O HOH A 211 4272 3960 3697 124 137 -361 O HETATM 1809 O HOH A 212 -27.607 13.628 180.407 1.00 39.29 O ANISOU 1809 O HOH A 212 5811 4399 4718 316 -357 -335 O HETATM 1810 O HOH A 213 -40.864 20.735 147.631 1.00 32.41 O ANISOU 1810 O HOH A 213 4171 4215 3929 121 42 -597 O HETATM 1811 O HOH A 214 -30.037 32.423 156.011 1.00 37.18 O ANISOU 1811 O HOH A 214 4891 4745 4491 21 123 -444 O HETATM 1812 O HOH A 215 -14.410 7.041 171.496 1.00 40.59 O ANISOU 1812 O HOH A 215 5242 4739 5443 602 -672 -672 O HETATM 1813 O HOH A 216 -38.378 33.008 164.504 1.00 24.86 O ANISOU 1813 O HOH A 216 3532 3018 2896 143 141 -356 O HETATM 1814 O HOH A 217 -26.884 11.008 178.316 1.00 40.96 O ANISOU 1814 O HOH A 217 5923 4613 5028 344 -375 -370 O HETATM 1815 O HOH A 218 -41.907 29.168 150.874 1.00 21.59 O ANISOU 1815 O HOH A 218 2887 2822 2494 143 89 -442 O HETATM 1816 O HOH A 219 -42.177 21.444 150.116 1.00 22.21 O ANISOU 1816 O HOH A 219 2873 2891 2675 121 51 -553 O HETATM 1817 O HOH A 220 -45.926 13.990 161.793 1.00 11.80 O ANISOU 1817 O HOH A 220 1623 1301 1559 56 156 -458 O HETATM 1818 O HOH A 221 -33.684 16.663 180.814 1.00 48.38 O ANISOU 1818 O HOH A 221 7031 5580 5771 227 -84 -272 O HETATM 1819 O HOH A 222 -26.128 13.962 156.648 1.00 30.34 O ANISOU 1819 O HOH A 222 3824 3800 3902 235 -14 -675 O HETATM 1820 O HOH A 223 -32.744 17.704 160.922 1.00 14.75 O ANISOU 1820 O HOH A 223 2018 1758 1829 163 16 -532 O HETATM 1821 O HOH A 224 -50.793 25.319 160.937 1.00 31.09 O ANISOU 1821 O HOH A 224 3994 3893 3926 167 236 -379 O HETATM 1822 O HOH A 225 -45.738 33.301 165.503 1.00 33.13 O ANISOU 1822 O HOH A 225 4551 4058 3978 228 259 -320 O HETATM 1823 O HOH A 226 -14.328 4.245 162.630 1.00 35.48 O ANISOU 1823 O HOH A 226 4322 4238 4920 632 -395 -851 O HETATM 1824 O HOH A 227 -22.314 7.870 154.858 1.00 35.96 O ANISOU 1824 O HOH A 227 4458 4473 4730 356 -54 -780 O HETATM 1825 O HOH A 228 -47.835 34.787 158.157 1.00 26.39 O ANISOU 1825 O HOH A 228 3565 3312 3150 254 175 -331 O HETATM 1826 O HOH A 229 -14.380 20.634 173.094 1.00 34.46 O ANISOU 1826 O HOH A 229 4438 4153 4502 265 -599 -600 O HETATM 1827 O HOH A 230 -38.977 -0.212 169.723 1.00 32.58 O ANISOU 1827 O HOH A 230 4728 3412 4238 113 -13 -415 O HETATM 1828 O HOH A 231 -49.768 26.562 163.023 1.00 31.74 O ANISOU 1828 O HOH A 231 4152 3943 3964 181 270 -356 O HETATM 1829 O HOH A 232 -40.507 15.574 154.481 1.00 12.88 O ANISOU 1829 O HOH A 232 1700 1584 1610 112 53 -582 O HETATM 1830 O HOH A 233 -36.975 13.877 162.478 1.00 25.39 O ANISOU 1830 O HOH A 233 3426 3009 3213 147 39 -505 O HETATM 1831 O HOH A 234 -40.291 23.625 164.576 1.00 8.06 O ANISOU 1831 O HOH A 234 1289 883 889 140 144 -396 O HETATM 1832 O HOH A 235 -24.033 2.276 159.833 1.00 37.75 O ANISOU 1832 O HOH A 235 4876 4459 5009 421 -194 -724 O HETATM 1833 O HOH A 236 -52.542 13.610 163.076 1.00 24.59 O ANISOU 1833 O HOH A 236 3132 2915 3296 -18 273 -413 O HETATM 1834 O HOH A 237 -42.221 34.894 153.478 1.00 20.79 O ANISOU 1834 O HOH A 237 2894 2657 2347 167 119 -357 O HETATM 1835 O HOH A 238 -43.776 29.251 169.740 1.00 12.82 O ANISOU 1835 O HOH A 238 2063 1416 1390 191 265 -318 O HETATM 1836 O HOH A 239 -22.162 21.722 170.281 1.00 23.66 O ANISOU 1836 O HOH A 239 3228 2794 2969 196 -292 -516 O HETATM 1837 O HOH A 240 -32.758 16.354 158.089 1.00 17.45 O ANISOU 1837 O HOH A 240 2309 2136 2187 164 26 -574 O HETATM 1838 O HOH A 241 -34.529 14.847 178.884 1.00 41.72 O ANISOU 1838 O HOH A 241 6099 4752 5001 215 -50 -284 O HETATM 1839 O HOH A 242 -33.511 16.666 148.809 1.00 21.04 O ANISOU 1839 O HOH A 242 2699 2736 2559 137 78 -630 O HETATM 1840 O HOH A 243 -37.355 6.127 170.087 1.00 16.92 O ANISOU 1840 O HOH A 243 2655 1614 2160 156 -3 -406 O HETATM 1841 O HOH A 244 -31.614 20.005 166.090 1.00 23.29 O ANISOU 1841 O HOH A 244 3219 2770 2861 167 -27 -465 O HETATM 1842 O HOH A 245 -58.181 14.907 151.903 1.00 48.48 O ANISOU 1842 O HOH A 245 5824 6157 6438 -18 -15 -573 O HETATM 1843 O HOH A 246 -21.209 11.841 157.097 1.00 37.58 O ANISOU 1843 O HOH A 246 4633 4716 4931 329 -70 -769 O HETATM 1844 O HOH A 247 -28.199 19.841 161.935 1.00 18.74 O ANISOU 1844 O HOH A 247 2490 2289 2342 167 -34 -545 O HETATM 1845 O HOH A 248 -40.248 35.981 166.758 1.00 32.20 O ANISOU 1845 O HOH A 248 4557 3894 3783 176 177 -321 O HETATM 1846 O HOH A 249 -26.778 2.640 167.883 1.00 17.40 O ANISOU 1846 O HOH A 249 2587 1676 2349 396 -288 -567 O HETATM 1847 O HOH A 250 -35.502 18.162 148.594 1.00 20.96 O ANISOU 1847 O HOH A 250 2707 2737 2522 124 75 -610 O HETATM 1848 O HOH A 251 -29.652 24.901 158.875 1.00 28.45 O ANISOU 1848 O HOH A 251 3715 3601 3495 103 51 -513 O HETATM 1849 O HOH A 252 -28.739 21.823 166.264 1.00 25.51 O ANISOU 1849 O HOH A 252 3473 3075 3145 160 -72 -481 O HETATM 1850 O HOH A 253 -41.438 14.291 148.116 1.00 33.13 O ANISOU 1850 O HOH A 253 4234 4224 4130 105 1 -673 O HETATM 1851 O HOH A 254 -47.209 29.381 161.998 1.00 36.42 O ANISOU 1851 O HOH A 254 4809 4546 4484 198 225 -354 O HETATM 1852 O HOH A 255 -20.064 12.440 159.594 1.00 34.51 O ANISOU 1852 O HOH A 255 4251 4298 4564 338 -137 -740 O HETATM 1853 O HOH A 256 -19.475 12.840 177.167 1.00 44.58 O ANISOU 1853 O HOH A 256 6123 5180 5634 420 -621 -489 O HETATM 1854 O HOH A 257 -20.992 19.786 166.145 1.00 28.86 O ANISOU 1854 O HOH A 257 3712 3534 3718 213 -230 -582 O HETATM 1855 O HOH A 258 -33.697 9.369 149.475 1.00 30.07 O ANISOU 1855 O HOH A 258 3857 3762 3807 174 19 -699 O HETATM 1856 O HOH A 259 -32.561 29.820 150.142 1.00 36.30 O ANISOU 1856 O HOH A 259 4743 4723 4328 54 161 -486 O HETATM 1857 O HOH A 260 -30.149 8.349 154.060 1.00 30.20 O ANISOU 1857 O HOH A 260 3873 3707 3896 231 -14 -686 O HETATM 1858 O HOH A 261 -33.281 12.907 175.007 1.00 28.35 O ANISOU 1858 O HOH A 261 4224 3113 3433 222 -90 -351 O HETATM 1859 O HOH A 262 -28.609 2.936 179.010 1.00 36.45 O ANISOU 1859 O HOH A 262 5538 3807 4505 391 -383 -322 O HETATM 1860 O HOH A 263 -36.989 35.747 157.973 1.00 29.39 O ANISOU 1860 O HOH A 263 4047 3679 3440 101 134 -359 O HETATM 1861 O HOH A 264 -26.449 8.525 151.891 1.00 44.99 O ANISOU 1861 O HOH A 264 5666 5648 5781 273 11 -742 O HETATM 1862 O HOH A 265 -59.240 12.938 155.309 1.00 53.62 O ANISOU 1862 O HOH A 265 6459 6736 7176 -82 96 -536 O HETATM 1863 O HOH A 266 -13.983 14.385 172.144 1.00 39.29 O ANISOU 1863 O HOH A 266 5012 4712 5204 423 -631 -639 O HETATM 1864 O HOH A 267 -50.029 20.344 151.099 1.00 28.97 O ANISOU 1864 O HOH A 267 3609 3729 3670 109 15 -530 O HETATM 1865 O HOH A 268 -46.462 28.988 169.040 1.00 18.29 O ANISOU 1865 O HOH A 268 2694 2131 2124 202 317 -312 O HETATM 1866 O HOH A 269 -38.156 25.975 175.886 1.00 37.45 O ANISOU 1866 O HOH A 269 5410 4405 4414 175 131 -302 O HETATM 1867 O HOH A 270 -58.573 19.990 152.284 1.00 44.06 O ANISOU 1867 O HOH A 270 5270 5659 5813 88 12 -513 O HETATM 1868 O HOH A 271 -32.025 23.037 165.459 1.00 23.00 O ANISOU 1868 O HOH A 271 3180 2769 2790 143 3 -451 O HETATM 1869 O HOH A 272 -30.147 20.556 178.992 1.00 30.35 O ANISOU 1869 O HOH A 272 4611 3395 3526 226 -194 -340 O HETATM 1870 O HOH A 273 -30.561 28.205 158.236 1.00 34.00 O ANISOU 1870 O HOH A 273 4457 4316 4147 73 81 -476 O HETATM 1871 O HOH A 274 -34.844 15.308 145.273 1.00 40.05 O ANISOU 1871 O HOH A 274 5125 5167 4927 135 69 -668 O HETATM 1872 O HOH A 275 -60.599 23.153 155.900 1.00 40.34 O ANISOU 1872 O HOH A 275 4764 5182 5380 151 145 -441 O HETATM 1873 O HOH A 276 -19.551 9.956 176.687 1.00 36.24 O ANISOU 1873 O HOH A 276 5075 4076 4617 472 -631 -496 O HETATM 1874 O HOH A 277 -29.145 15.776 180.236 1.00 35.93 O ANISOU 1874 O HOH A 277 5384 4011 4257 277 -276 -325 O HETATM 1875 O HOH A 278 -33.470 17.991 165.897 1.00 31.13 O ANISOU 1875 O HOH A 278 4220 3738 3869 169 -2 -462 O HETATM 1876 O HOH A 279 -44.626 30.648 166.637 1.00 20.07 O ANISOU 1876 O HOH A 279 2899 2390 2336 198 252 -328 O HETATM 1877 O HOH A 280 -23.333 -0.193 168.729 1.00 51.64 O ANISOU 1877 O HOH A 280 6925 5946 6750 511 -412 -593 O HETATM 1878 O HOH A 281 -24.795 21.248 166.061 1.00 24.58 O ANISOU 1878 O HOH A 281 3272 2980 3090 175 -146 -528 O HETATM 1879 O HOH A 282 -37.840 33.012 168.587 1.00 25.70 O ANISOU 1879 O HOH A 282 3739 3055 2970 150 133 -340 O HETATM 1880 O HOH A 283 -24.835 10.593 180.105 1.00 39.41 O ANISOU 1880 O HOH A 283 5787 4372 4815 391 -493 -367 O HETATM 1881 O HOH A 284 -18.073 2.586 174.295 1.00 38.67 O ANISOU 1881 O HOH A 284 5334 4266 5095 640 -694 -573 O HETATM 1882 O HOH A 285 -34.599 17.646 175.456 1.00 18.93 O ANISOU 1882 O HOH A 285 3035 1987 2171 194 -19 -334 O HETATM 1883 O HOH A 286 -38.668 16.870 177.490 1.00 36.00 O ANISOU 1883 O HOH A 286 5297 4093 4289 166 121 -272 O HETATM 1884 O HOH A 287 -24.250 -2.421 170.465 1.00 41.48 O ANISOU 1884 O HOH A 287 5766 4550 5446 516 -440 -543 O HETATM 1885 O HOH A 288 -25.083 23.092 167.465 1.00 46.33 O ANISOU 1885 O HOH A 288 6081 5715 5805 155 -156 -501 O HETATM 1886 O HOH A 289 -42.276 38.989 159.606 1.00 25.12 O ANISOU 1886 O HOH A 289 3586 3078 2880 198 166 -307 O HETATM 1887 O HOH A 290 -28.844 18.410 179.483 1.00 28.84 O ANISOU 1887 O HOH A 290 4431 3171 3358 254 -263 -344 O HETATM 1888 O HOH A 291 -29.964 2.609 166.098 1.00 22.34 O ANISOU 1888 O HOH A 291 3203 2321 2966 320 -192 -567 O HETATM 1889 O HOH A 292 -34.364 -4.347 169.142 1.00 42.16 O ANISOU 1889 O HOH A 292 5997 4515 5507 245 -175 -479 O HETATM 1890 O HOH A 293 -40.214 8.146 153.067 1.00 31.18 O ANISOU 1890 O HOH A 293 4034 3791 4021 103 -7 -681 O HETATM 1891 O HOH A 294 -50.010 20.908 166.688 1.00 19.73 O ANISOU 1891 O HOH A 294 2675 2327 2494 108 335 -342 O HETATM 1892 O HOH A 295 -24.907 15.230 158.794 1.00 31.41 O ANISOU 1892 O HOH A 295 3965 3922 4048 238 -50 -662 O HETATM 1893 O HOH A 296 -28.885 0.600 167.664 1.00 25.22 O ANISOU 1893 O HOH A 296 3635 2602 3343 362 -251 -550 O HETATM 1894 O HOH A 297 -26.645 19.866 155.227 1.00 47.22 O ANISOU 1894 O HOH A 297 5959 6032 5951 152 58 -632 O HETATM 1895 O HOH A 298 -43.197 37.557 153.196 1.00 38.94 O ANISOU 1895 O HOH A 298 5247 4935 4615 194 116 -323 O HETATM 1896 O HOH A 299 -12.760 5.946 164.764 1.00 37.03 O ANISOU 1896 O HOH A 299 4490 4446 5135 631 -480 -827 O HETATM 1897 O HOH A 300 -35.588 19.265 183.188 1.00 48.27 O ANISOU 1897 O HOH A 300 7148 5547 5645 217 4 -236 O HETATM 1898 O HOH A 301 -33.360 35.886 152.608 1.00 44.69 O ANISOU 1898 O HOH A 301 5932 5706 5341 27 160 -386 O HETATM 1899 O HOH A 302 -30.564 13.767 148.392 1.00 39.55 O ANISOU 1899 O HOH A 302 5011 5066 4949 172 79 -681 O HETATM 1900 O HOH A 303 -26.529 19.207 159.410 1.00 38.55 O ANISOU 1900 O HOH A 303 4917 4851 4881 173 -16 -595 O HETATM 1901 O HOH A 304 -19.308 1.658 176.435 1.00 44.66 O ANISOU 1901 O HOH A 304 6255 4931 5784 636 -719 -508 O HETATM 1902 O HOH A 305 -35.126 -2.103 164.237 1.00 37.31 O ANISOU 1902 O HOH A 305 5173 4082 4922 215 -124 -583 O HETATM 1903 O HOH A 306 -31.483 26.343 173.698 1.00 34.52 O ANISOU 1903 O HOH A 306 4934 4079 4105 157 -68 -378 O HETATM 1904 O HOH A 307 -39.599 24.422 174.228 1.00 34.00 O ANISOU 1904 O HOH A 307 4900 3989 4027 169 172 -311 O HETATM 1905 O HOH A 308 -27.345 -0.086 174.757 1.00 32.97 O ANISOU 1905 O HOH A 308 4902 3402 4222 430 -398 -418 O HETATM 1906 O HOH A 309 -40.404 16.677 156.842 1.00 20.30 O ANISOU 1906 O HOH A 309 2667 2500 2546 115 73 -538 O HETATM 1907 O HOH A 310 -31.881 6.231 181.294 1.00 38.92 O ANISOU 1907 O HOH A 310 5956 4149 4682 299 -235 -245 O HETATM 1908 O HOH A 311 -34.498 16.955 163.081 1.00 32.81 O ANISOU 1908 O HOH A 311 4366 3990 4112 160 22 -495 O HETATM 1909 O HOH A 312 -27.926 20.399 163.956 1.00 13.35 O ANISOU 1909 O HOH A 312 1851 1573 1646 169 -63 -521 O HETATM 1910 O HOH A 313 -37.085 16.123 168.154 1.00 24.89 O ANISOU 1910 O HOH A 313 3515 2871 3072 153 56 -411 O HETATM 1911 O HOH A 314 -12.129 4.247 167.919 1.00 47.74 O ANISOU 1911 O HOH A 314 5950 5688 6500 707 -634 -792 O HETATM 1912 O HOH A 315 -38.626 10.113 151.769 1.00 34.34 O ANISOU 1912 O HOH A 315 4417 4260 4371 123 5 -668 O HETATM 1913 O HOH A 316 -38.436 28.277 176.171 1.00 33.30 O ANISOU 1913 O HOH A 316 4895 3890 3866 176 142 -291 O HETATM 1914 O HOH A 317 -33.718 15.709 164.982 1.00 31.10 O ANISOU 1914 O HOH A 317 4195 3721 3901 176 -7 -485 O HETATM 1915 O HOH A 318 -20.256 9.569 179.177 1.00 38.12 O ANISOU 1915 O HOH A 318 5469 4236 4778 481 -673 -445 O HETATM 1916 O HOH A 319 -59.330 20.998 154.099 1.00 43.95 O ANISOU 1916 O HOH A 319 5242 5636 5821 104 76 -480 O HETATM 1917 O HOH A 320 -38.115 27.709 149.216 1.00 36.46 O ANISOU 1917 O HOH A 320 4762 4737 4355 110 107 -490 O HETATM 1918 O HOH A 321 -41.019 14.588 176.452 1.00 30.97 O ANISOU 1918 O HOH A 321 4608 3445 3715 130 192 -264 O HETATM 1919 O HOH A 322 -38.534 4.038 171.518 1.00 23.31 O ANISOU 1919 O HOH A 322 3549 2333 2974 132 18 -371 O HETATM 1920 O HOH A 323 -11.811 5.445 170.591 1.00 49.51 O ANISOU 1920 O HOH A 323 6245 5880 6685 693 -732 -740 O HETATM 1921 O HOH A 324 -32.101 35.841 155.386 1.00 43.34 O ANISOU 1921 O HOH A 324 5760 5499 5207 17 141 -391 O HETATM 1922 O HOH A 325 -28.940 14.994 148.898 1.00 44.09 O ANISOU 1922 O HOH A 325 5564 5663 5528 173 95 -680 O HETATM 1923 O HOH A 326 -26.357 0.000 176.938 0.50 40.12 O ANISOU 1923 O HOH A 326 5916 4239 5087 0 0 -394 O HETATM 1924 O HOH A 327 -20.539 22.108 168.212 1.00 41.42 O ANISOU 1924 O HOH A 327 5360 5103 5273 181 -276 -553 O HETATM 1925 O HOH A 328 -36.813 29.510 149.096 1.00 42.05 O ANISOU 1925 O HOH A 328 5495 5448 5033 94 127 -471 O HETATM 1926 O HOH A 329 -23.185 14.005 156.442 1.00 41.42 O ANISOU 1926 O HOH A 329 5156 5232 5351 266 -24 -727 O HETATM 1927 O HOH A 330 -52.243 22.118 151.661 0.50 35.01 O ANISOU 1927 O HOH A 330 4344 4500 4460 135 233 -135 O HETATM 1928 O HOH A 331 -42.182 40.309 161.553 1.00 46.39 O ANISOU 1928 O HOH A 331 6342 5727 5558 208 179 -298 O HETATM 1929 O HOH A 332 -22.022 -1.547 170.282 1.00 48.48 O ANISOU 1929 O HOH A 332 6577 5482 6361 568 -494 -579 O HETATM 1930 O HOH A 333 -33.658 26.903 167.282 1.00 29.27 O ANISOU 1930 O HOH A 333 4069 3540 3513 131 37 -403 O HETATM 1931 O HOH A 334 -21.337 13.176 178.377 1.00 40.18 O ANISOU 1931 O HOH A 334 5680 4585 5000 395 -578 -445 O HETATM 1932 O HOH A 335 -37.144 -1.393 165.526 1.00 25.82 O ANISOU 1932 O HOH A 335 3752 2608 3450 162 -81 -537 O HETATM 1933 O HOH A 336 -43.048 11.560 149.336 1.00 42.64 O ANISOU 1933 O HOH A 336 5430 5363 5408 83 -20 -699 O HETATM 1934 O HOH A 337 -22.668 15.399 158.173 1.00 42.83 O ANISOU 1934 O HOH A 337 5344 5402 5527 251 -53 -694 O HETATM 1935 O HOH A 338 -36.040 32.726 165.396 1.00 39.99 O ANISOU 1935 O HOH A 338 5462 4921 4810 121 105 -367 O HETATM 1936 O HOH A 339 -37.549 36.645 165.365 1.00 42.01 O ANISOU 1936 O HOH A 339 5794 5150 5019 135 135 -338 O HETATM 1937 O HOH A 340 -30.994 15.875 147.236 1.00 38.13 O ANISOU 1937 O HOH A 340 4840 4926 4722 151 102 -665 O HETATM 1938 O HOH A 341 -25.031 13.324 178.785 1.00 40.54 O ANISOU 1938 O HOH A 341 5837 4603 4965 346 -439 -390 O HETATM 1939 O HOH A 342 -21.823 11.271 179.712 1.00 44.61 O ANISOU 1939 O HOH A 342 6345 5072 5534 428 -606 -416 O HETATM 1940 O HOH A 343 -46.962 10.388 149.954 1.00 43.23 O ANISOU 1940 O HOH A 343 5460 5404 5561 30 -42 -686 O HETATM 1941 O HOH A 344 -17.753 0.774 172.942 1.00 35.36 O ANISOU 1941 O HOH A 344 4871 3837 4726 673 -682 -603 O HETATM 1942 O HOH A 345 -35.882 33.295 167.557 1.00 41.14 O ANISOU 1942 O HOH A 345 5675 5026 4932 127 98 -358 O HETATM 1943 O HOH A 346 -39.631 40.452 162.215 1.00 41.15 O ANISOU 1943 O HOH A 346 5706 5049 4880 161 159 -306 O HETATM 1944 O HOH A 347 -33.883 30.887 147.858 1.00 41.08 O ANISOU 1944 O HOH A 347 5385 5350 4874 55 168 -472 O HETATM 1945 O HOH A 348 -59.124 13.009 150.272 1.00 51.59 O ANISOU 1945 O HOH A 348 6180 6546 6876 -61 -82 -621 O HETATM 1946 O HOH A 349 -32.606 29.526 166.330 1.00 47.18 O ANISOU 1946 O HOH A 349 6331 5831 5766 108 34 -404 O HETATM 1947 O HOH A 350 -44.654 10.305 150.217 1.00 43.95 O ANISOU 1947 O HOH A 350 5585 5490 5623 57 -28 -693 O HETATM 1948 O HOH A 351 -37.395 39.134 164.221 1.00 38.05 O ANISOU 1948 O HOH A 351 5321 4641 4494 126 136 -326 O HETATM 1949 O HOH D 101 -35.262 13.855 170.876 1.00 32.63 O ANISOU 1949 O HOH D 101 4597 3760 4040 182 -6 -394 O HETATM 1950 O HOH D 102 -56.832 25.181 182.816 1.00 43.70 O ANISOU 1950 O HOH D 102 6180 5158 5266 187 945 -157 O HETATM 1951 O HOH D 103 -36.204 0.627 150.306 1.00 40.18 O ANISOU 1951 O HOH D 103 5240 4820 5207 169 -64 -773 O HETATM 1952 O HOH D 104 -51.196 29.333 165.864 1.00 44.58 O ANISOU 1952 O HOH D 104 5844 5536 5559 230 353 -320 O HETATM 1953 O HOH D 105 -54.011 24.593 178.385 1.00 34.34 O ANISOU 1953 O HOH D 105 4875 4023 4148 175 729 -209 O HETATM 1954 O HOH D 106 -52.143 22.530 167.175 1.00 24.02 O ANISOU 1954 O HOH D 106 3187 2888 3052 127 392 -326 O HETATM 1955 O HOH D 107 -36.529 19.266 168.189 1.00 17.51 O ANISOU 1955 O HOH D 107 2579 1977 2097 154 60 -403 O HETATM 1956 O HOH D 108 -36.026 15.462 176.756 1.00 45.84 O ANISOU 1956 O HOH D 108 6516 5332 5569 189 16 -302 O HETATM 1957 O HOH D 109 -46.375 5.439 168.330 1.00 26.94 O ANISOU 1957 O HOH D 109 3789 2908 3539 -32 212 -374 O HETATM 1958 O HOH D 110 -40.200 2.203 170.361 1.00 22.99 O ANISOU 1958 O HOH D 110 3486 2262 2986 87 46 -384 O HETATM 1959 O HOH D 111 -51.167 31.904 183.097 1.00 40.86 O ANISOU 1959 O HOH D 111 5986 4790 4750 271 635 -175 O HETATM 1960 O HOH D 112 -46.286 28.725 166.300 1.00 11.65 O ANISOU 1960 O HOH D 112 1775 1336 1316 193 274 -332 O HETATM 1961 O HOH D 113 -57.504 29.494 175.502 1.00 42.73 O ANISOU 1961 O HOH D 113 5735 5191 5311 282 762 -247 O HETATM 1962 O HOH D 114 -54.934 29.502 171.870 1.00 35.70 O ANISOU 1962 O HOH D 114 4795 4338 4430 264 582 -274 O HETATM 1963 O HOH D 115 -36.153 -1.903 154.453 1.00 33.59 O ANISOU 1963 O HOH D 115 4486 3836 4441 176 -88 -738 O HETATM 1964 O HOH D 116 -55.349 23.153 170.566 1.00 34.43 O ANISOU 1964 O HOH D 116 4520 4176 4386 136 554 -283 O HETATM 1965 O HOH D 117 -43.372 4.064 159.462 1.00 19.87 O ANISOU 1965 O HOH D 117 2712 2139 2700 28 31 -588 O HETATM 1966 O HOH D 118 -35.220 26.475 168.905 1.00 18.76 O ANISOU 1966 O HOH D 118 2791 2173 2162 144 61 -381 O HETATM 1967 O HOH D 119 -47.110 26.836 162.880 1.00 9.34 O ANISOU 1967 O HOH D 119 1367 1099 1083 173 233 -363 O HETATM 1968 O HOH D 120 -36.230 0.843 164.403 1.00 22.08 O ANISOU 1968 O HOH D 120 3199 2235 2954 183 -79 -560 O HETATM 1969 O HOH D 121 -29.927 4.274 154.604 1.00 33.42 O ANISOU 1969 O HOH D 121 4321 4019 4356 267 -54 -714 O HETATM 1970 O HOH D 122 -38.980 11.113 165.492 1.00 27.68 O ANISOU 1970 O HOH D 122 3807 3186 3523 126 60 -458 O HETATM 1971 O HOH D 123 -39.070 14.391 165.732 1.00 20.10 O ANISOU 1971 O HOH D 123 2836 2283 2518 130 83 -438 O HETATM 1972 O HOH D 124 -38.277 6.162 167.489 1.00 13.53 O ANISOU 1972 O HOH D 124 2129 1239 1771 135 15 -449 O HETATM 1973 O HOH D 125 -43.043 22.680 164.851 1.00 7.95 O ANISOU 1973 O HOH D 125 1256 861 904 136 187 -383 O HETATM 1974 O HOH D 126 -60.062 30.969 179.966 1.00 40.02 O ANISOU 1974 O HOH D 126 5477 4813 4917 311 922 -202 O HETATM 1975 O HOH D 127 -35.794 3.284 165.354 1.00 25.08 O ANISOU 1975 O HOH D 127 3566 2671 3293 189 -65 -529 O HETATM 1976 O HOH D 128 -46.100 3.704 164.176 1.00 28.86 O ANISOU 1976 O HOH D 128 3931 3182 3852 -39 130 -471 O HETATM 1977 O HOH D 129 -18.341 -14.425 154.740 1.00 50.58 O ANISOU 1977 O HOH D 129 6610 5756 6854 761 -295 -952 O HETATM 1978 O HOH D 130 -49.380 28.984 170.578 1.00 37.66 O ANISOU 1978 O HOH D 130 5141 4571 4597 222 410 -293 O HETATM 1979 O HOH D 131 -42.318 17.201 165.056 1.00 8.36 O ANISOU 1979 O HOH D 131 1305 851 1020 110 154 -412 O HETATM 1980 O HOH D 132 -41.483 23.050 173.473 1.00 16.63 O ANISOU 1980 O HOH D 132 2652 1799 1868 160 221 -306 O HETATM 1981 O HOH D 133 -36.688 -2.063 159.443 1.00 25.96 O ANISOU 1981 O HOH D 133 3614 2749 3502 168 -92 -664 O HETATM 1982 O HOH D 134 -23.855 -2.165 157.071 1.00 48.99 O ANISOU 1982 O HOH D 134 6312 5829 6471 462 -183 -782 O HETATM 1983 O HOH D 135 -39.646 5.702 156.453 1.00 21.96 O ANISOU 1983 O HOH D 135 2931 2505 2906 109 -11 -661 O HETATM 1984 O HOH D 136 -47.925 20.134 167.876 1.00 21.04 O ANISOU 1984 O HOH D 136 2916 2455 2621 106 312 -338 O HETATM 1985 O HOH D 137 -53.404 21.929 176.754 1.00 33.07 O ANISOU 1985 O HOH D 137 4648 3867 4052 123 662 -217 O HETATM 1986 O HOH D 138 -35.696 -3.056 157.025 1.00 41.23 O ANISOU 1986 O HOH D 138 5513 4718 5436 190 -103 -708 O HETATM 1987 O HOH D 139 -40.274 -0.369 173.804 1.00 44.42 O ANISOU 1987 O HOH D 139 6398 4816 5666 78 48 -306 O HETATM 1988 O HOH D 140 -30.877 -4.501 151.086 1.00 34.37 O ANISOU 1988 O HOH D 140 4553 3966 4541 302 -97 -825 O HETATM 1989 O HOH D 141 -23.112 -0.848 155.405 1.00 52.01 O ANISOU 1989 O HOH D 141 6630 6289 6843 456 -145 -808 O HETATM 1990 O HOH D 142 -52.394 25.130 179.899 1.00 44.06 O ANISOU 1990 O HOH D 142 6230 5215 5295 189 705 -202 O HETATM 1991 O HOH D 143 -40.921 -1.095 171.826 1.00 54.98 O ANISOU 1991 O HOH D 143 7659 6173 7060 56 49 -348 O HETATM 1992 O HOH D 144 -45.628 2.823 161.586 1.00 37.14 O ANISOU 1992 O HOH D 144 4933 4252 4925 -33 77 -536 O HETATM 1993 O HOH D 145 -47.193 3.501 166.429 1.00 44.89 O ANISOU 1993 O HOH D 145 6013 5166 5878 -68 187 -416 O HETATM 1994 O HOH D 146 -55.131 26.208 184.824 1.00 46.25 O ANISOU 1994 O HOH D 146 6653 5437 5484 205 894 -138 O HETATM 1995 O HOH D 147 -42.662 4.678 157.222 1.00 33.63 O ANISOU 1995 O HOH D 147 4413 3939 4426 48 6 -634 O HETATM 1996 O HOH D 148 -27.710 -4.561 147.863 1.00 43.42 O ANISOU 1996 O HOH D 148 5639 5192 5666 371 -59 -894 O HETATM 1997 O HOH D 149 -36.808 13.290 179.185 1.00 42.58 O ANISOU 1997 O HOH D 149 6238 4825 5114 188 32 -254 O HETATM 1998 O HOH D 150 -61.777 30.805 181.843 1.00 44.50 O ANISOU 1998 O HOH D 150 6053 5369 5486 311 1027 -184 O HETATM 1999 O HOH D 151 -48.471 29.943 164.881 1.00 27.56 O ANISOU 1999 O HOH D 151 3732 3382 3357 217 290 -329 O HETATM 2000 O HOH D 152 -29.875 -6.101 147.772 1.00 44.52 O ANISOU 2000 O HOH D 152 5839 5269 5808 333 -81 -897 O HETATM 2001 O HOH E 101 -31.143 -7.738 151.729 1.00 42.27 O ANISOU 2001 O HOH E 101 5626 4851 5582 315 -129 -841 O HETATM 2002 O HOH E 102 -43.947 27.121 181.291 1.00 37.08 O ANISOU 2002 O HOH E 102 5555 4282 4254 201 363 -211 O HETATM 2003 O HOH E 103 -26.642 -13.326 156.365 1.00 42.97 O ANISOU 2003 O HOH E 103 5835 4702 5789 490 -246 -825 O HETATM 2004 O HOH E 104 -55.317 9.683 166.120 1.00 47.87 O ANISOU 2004 O HOH E 104 6100 5748 6340 -128 388 -368 O HETATM 2005 O HOH E 105 -59.160 37.856 172.501 1.00 40.57 O ANISOU 2005 O HOH E 105 5406 4965 5045 466 654 -270 O HETATM 2006 O HOH E 106 -28.514 -1.152 165.646 1.00 28.79 O ANISOU 2006 O HOH E 106 4040 3061 3839 375 -245 -592 O HETATM 2007 O HOH E 107 -32.745 -8.942 152.950 1.00 42.68 O ANISOU 2007 O HOH E 107 5735 4826 5657 278 -145 -823 O HETATM 2008 O HOH E 108 -39.201 30.725 174.234 1.00 29.67 O ANISOU 2008 O HOH E 108 4374 3474 3427 174 164 -297 O HETATM 2009 O HOH E 109 -48.973 27.674 180.514 1.00 34.39 O ANISOU 2009 O HOH E 109 5105 3980 3982 216 553 -203 O HETATM 2010 O HOH E 110 -45.894 19.728 182.012 1.00 36.14 O ANISOU 2010 O HOH E 110 5470 4075 4188 141 464 -177 O HETATM 2011 O HOH E 111 -43.751 24.220 174.912 1.00 16.90 O ANISOU 2011 O HOH E 111 2728 1819 1873 169 307 -280 O HETATM 2012 O HOH E 112 -42.540 35.359 174.100 1.00 48.86 O ANISOU 2012 O HOH E 112 6817 5909 5839 212 248 -267 O HETATM 2013 O HOH E 113 -31.705 -10.134 148.650 1.00 45.03 O ANISOU 2013 O HOH E 113 6013 5174 5923 311 -129 -913 O HETATM 2014 O HOH E 114 -35.486 9.805 162.620 1.00 29.73 O ANISOU 2014 O HOH E 114 3999 3481 3815 174 -12 -544 O HETATM 2015 O HOH E 115 -28.375 4.767 167.064 1.00 12.15 O ANISOU 2015 O HOH E 115 1892 1071 1653 341 -222 -563 O HETATM 2016 O HOH E 116 -39.130 14.623 158.608 1.00 13.44 O ANISOU 2016 O HOH E 116 1830 1574 1703 122 60 -541 O HETATM 2017 O HOH E 117 -23.438 4.552 165.796 1.00 19.82 O ANISOU 2017 O HOH E 117 2724 2103 2704 441 -309 -645 O HETATM 2018 O HOH E 118 -47.228 32.987 179.307 1.00 27.20 O ANISOU 2018 O HOH E 118 4178 3105 3053 250 436 -217 O HETATM 2019 O HOH E 119 -46.839 16.082 165.989 1.00 16.37 O ANISOU 2019 O HOH E 119 2287 1842 2091 68 244 -380 O HETATM 2020 O HOH E 120 -52.440 5.365 161.689 1.00 39.54 O ANISOU 2020 O HOH E 120 5060 4645 5317 -146 194 -484 O HETATM 2021 O HOH E 121 -37.807 -16.466 150.475 1.00 27.06 O ANISOU 2021 O HOH E 121 3952 2578 3753 133 -198 -915 O HETATM 2022 O HOH E 122 -40.704 33.948 173.696 1.00 30.20 O ANISOU 2022 O HOH E 122 4440 3551 3484 189 201 -282 O HETATM 2023 O HOH E 123 -23.222 4.064 161.956 1.00 21.68 O ANISOU 2023 O HOH E 123 2848 2424 2968 430 -233 -703 O HETATM 2024 O HOH E 124 -50.056 23.651 179.239 1.00 33.02 O ANISOU 2024 O HOH E 124 4852 3802 3891 166 597 -208 O HETATM 2025 O HOH E 125 -44.218 37.061 169.171 1.00 47.87 O ANISOU 2025 O HOH E 125 6575 5847 5765 236 258 -287 O HETATM 2026 O HOH E 126 -36.265 13.911 153.618 1.00 17.09 O ANISOU 2026 O HOH E 126 2232 2118 2145 140 37 -612 O HETATM 2027 O HOH E 127 -33.313 13.271 160.335 1.00 18.79 O ANISOU 2027 O HOH E 127 2530 2214 2396 184 -5 -573 O HETATM 2028 O HOH E 128 -32.462 -5.251 160.269 1.00 32.07 O ANISOU 2028 O HOH E 128 4435 3446 4305 281 -161 -674 O HETATM 2029 O HOH E 129 -29.743 6.194 156.433 1.00 16.45 O ANISOU 2029 O HOH E 129 2173 1879 2197 261 -57 -682 O HETATM 2030 O HOH E 130 -50.774 18.250 172.647 1.00 28.19 O ANISOU 2030 O HOH E 130 3923 3264 3522 69 472 -268 O HETATM 2031 O HOH E 131 -28.207 9.812 163.567 1.00 10.96 O ANISOU 2031 O HOH E 131 1575 1117 1473 284 -134 -601 O HETATM 2032 O HOH E 132 -47.659 24.164 180.245 1.00 31.96 O ANISOU 2032 O HOH E 132 4823 3637 3685 180 520 -211 O HETATM 2033 O HOH E 133 -33.440 -4.579 158.077 1.00 32.49 O ANISOU 2033 O HOH E 133 4438 3560 4346 249 -133 -705 O HETATM 2034 O HOH E 134 -42.500 16.113 174.728 1.00 23.86 O ANISOU 2034 O HOH E 134 3609 2610 2847 119 237 -280 O HETATM 2035 O HOH E 135 -32.685 7.204 155.095 1.00 22.81 O ANISOU 2035 O HOH E 135 2986 2713 2968 207 -24 -668 O HETATM 2036 O HOH E 136 -40.057 11.885 152.291 1.00 33.66 O ANISOU 2036 O HOH E 136 4322 4192 4274 110 17 -652 O HETATM 2037 O HOH E 137 -29.231 7.199 164.276 1.00 11.66 O ANISOU 2037 O HOH E 137 1724 1127 1579 294 -147 -591 O HETATM 2038 O HOH E 138 -47.984 5.762 164.213 1.00 23.69 O ANISOU 2038 O HOH E 138 3215 2588 3197 -57 179 -449 O HETATM 2039 O HOH E 139 -32.704 -6.216 154.108 1.00 42.12 O ANISOU 2039 O HOH E 139 5619 4821 5564 269 -129 -783 O HETATM 2040 O HOH E 140 -48.659 31.173 181.184 1.00 27.09 O ANISOU 2040 O HOH E 140 4210 3061 3021 247 521 -197 O HETATM 2041 O HOH E 141 -38.429 27.323 180.513 1.00 36.15 O ANISOU 2041 O HOH E 141 5434 4168 4135 190 143 -249 O HETATM 2042 O HOH E 142 -45.855 35.746 175.698 1.00 32.72 O ANISOU 2042 O HOH E 142 4790 3851 3791 252 347 -245 O HETATM 2043 O HOH E 143 -34.655 -2.381 161.498 1.00 37.02 O ANISOU 2043 O HOH E 143 5058 4110 4898 220 -120 -635 O HETATM 2044 O HOH E 144 -42.452 12.803 163.102 1.00 15.10 O ANISOU 2044 O HOH E 144 2119 1671 1948 86 116 -464 O HETATM 2045 O HOH E 145 -47.932 13.118 160.284 1.00 15.22 O ANISOU 2045 O HOH E 145 1994 1749 2040 28 151 -478 O HETATM 2046 O HOH E 146 -50.503 12.405 161.685 1.00 24.91 O ANISOU 2046 O HOH E 146 3198 2947 3318 -11 206 -450 O HETATM 2047 O HOH E 147 -44.640 15.625 164.715 1.00 18.22 O ANISOU 2047 O HOH E 147 2520 2086 2314 82 184 -411 O HETATM 2048 O HOH E 148 -43.840 12.771 160.610 1.00 17.13 O ANISOU 2048 O HOH E 148 2306 1972 2230 70 109 -496 O HETATM 2049 O HOH E 149 -29.524 -15.370 154.920 1.00 22.05 O ANISOU 2049 O HOH E 149 3263 1978 3138 408 -224 -847 O HETATM 2050 O HOH E 150 -52.307 9.241 157.919 1.00 47.54 O ANISOU 2050 O HOH E 150 5967 5817 6279 -74 121 -533 O HETATM 2051 O HOH E 151 -45.216 9.964 172.675 1.00 41.66 O ANISOU 2051 O HOH E 151 5783 4796 5250 33 271 -292 O HETATM 2052 O HOH E 152 -47.829 7.840 168.343 1.00 48.57 O ANISOU 2052 O HOH E 152 6071 5980 6404 -68 63 -577 O HETATM 2053 O HOH E 153 -51.359 19.911 178.023 1.00 36.33 O ANISOU 2053 O HOH E 153 5172 4216 4414 99 615 -201 O HETATM 2054 O HOH E 154 -52.831 40.050 168.970 1.00 42.41 O ANISOU 2054 O HOH E 154 5790 5168 5154 411 426 -273 O HETATM 2055 O HOH E 155 -46.787 34.342 167.821 1.00 44.08 O ANISOU 2055 O HOH E 155 5999 5405 5343 256 309 -305 O HETATM 2056 O HOH E 156 -37.674 10.896 163.760 1.00 32.82 O ANISOU 2056 O HOH E 156 4414 3868 4187 142 30 -499 O HETATM 2057 O HOH E 157 -60.015 31.107 177.195 1.00 35.87 O ANISOU 2057 O HOH E 157 4845 4329 4455 322 857 -230 O HETATM 2058 O HOH E 158 -24.416 2.252 166.796 1.00 33.55 O ANISOU 2058 O HOH E 158 4550 3756 4441 449 -326 -615 O HETATM 2059 O HOH E 159 -35.828 12.107 161.070 1.00 23.99 O ANISOU 2059 O HOH E 159 3222 2830 3064 161 12 -550 O HETATM 2060 O HOH E 160 -36.893 -14.351 148.334 1.00 42.08 O ANISOU 2060 O HOH E 160 5780 4611 5599 168 -183 -942 O HETATM 2061 O HOH E 161 -45.376 8.946 152.309 1.00 44.75 O ANISOU 2061 O HOH E 161 5694 5531 5777 35 -12 -669 O HETATM 2062 O HOH E 162 -48.546 30.732 169.234 1.00 40.14 O ANISOU 2062 O HOH E 162 5453 4904 4896 236 367 -301 O MASTER 355 0 0 6 0 0 0 6 2059 3 0 16 END
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Related entries of code: 5zfz
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
5z6z
RCSB PDB
PDBbind
19aa, >5Z6Z_3|Chain... *
5zfw
RCSB PDB
PDBbind
19aa, >5ZFW_3|Chain... at 94%
5zfy
RCSB PDB
PDBbind
19aa, >5ZFY_3|Chain... at 94%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
5zfz
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
human DUX4 homeodomains, DUX4-DH
Ligand Name
DNA1 A12T mutant
EC.Number
E.C.-.-.-.-
Resolution
1.9(Å)
Affinity (Kd/Ki/IC50)
Kd=58.14nM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) Biochem. Biophys. Res. Commun. Vol. 505: pp. 1161-1167
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q9UBX2
Entrez Gene ID
NCBI Entrez Gene ID:
100288687
ASD
Information of known allosteric effects of PDB entries
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