Browse entries in the PDBbind-CN Database

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Related entries of code: 6by8
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4gq4RCSB PDB    PDBbind489aa, >4GQ4_1|Chain... *
4og3RCSB PDB    PDBbind480aa, >4OG3_1|Chain... at 100%
4og4RCSB PDB    PDBbind480aa, >4OG4_1|Chain... at 100%
4og5RCSB PDB    PDBbind480aa, >4OG5_1|Chain... at 100%
4og6RCSB PDB    PDBbind489aa, >4OG6_1|Chain... at 99%
4og7RCSB PDB    PDBbind489aa, >4OG7_1|Chain... at 99%
4og8RCSB PDB    PDBbind489aa, >4OG8_1|Chain... at 99%
4x5yRCSB PDB    PDBbind489aa, >4X5Y_1|Chain... at 100%
4x5zRCSB PDB    PDBbind489aa, >4X5Z_1|Chain... at 100%
5db0RCSB PDB    PDBbind489aa, >5DB0_1|Chain... at 100%
5db1RCSB PDB    PDBbind489aa, >5DB1_1|Chain... at 100%
5db2RCSB PDB    PDBbind489aa, >5DB2_1|Chain... at 100%
5db3RCSB PDB    PDBbind489aa, >5DB3_1|Chain... at 100%
5dd9RCSB PDB    PDBbind489aa, >5DD9_1|Chain... at 100%
5ddaRCSB PDB    PDBbind489aa, >5DDA_1|Chain... at 100%
5ddbRCSB PDB    PDBbind489aa, >5DDB_1|Chain... at 100%
5ddcRCSB PDB    PDBbind489aa, >5DDC_1|Chain... at 100%
5dddRCSB PDB    PDBbind489aa, >5DDD_1|Chain... at 100%
5ddeRCSB PDB    PDBbind489aa, >5DDE_1|Chain... at 100%
5ddfRCSB PDB    PDBbind489aa, >5DDF_1|Chain... at 100%
6bxyRCSB PDB    PDBbind489aa, >6BXY_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6by8
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMenin
Ligand NameFNV
EC.Number E.C.-.-.-.-
Resolution 1.9(Å)
Affinity (Kd/Ki/IC50)IC50=123nM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J.Med.Chem. Vol. 61: pp. 4832-4850
Ligand Properties
Formula C29H31F3N7O2S
Molecular Weight 598.662
Exact Mass 598.221
No. of atoms 73
No. of bonds 78
Polar Surface Area 137.54
LOGP Value 4.83      (Computed with XLOGP3)
5.08      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): O00255  
Entrez Gene IDNCBI Entrez Gene ID: 4221  
ASDInformation of known allosteric effects of PDB entries
 
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