Browse entries in the PDBbind-CN Database
HEADER DNA BINDING PROTEIN/DNA 05-JAN-18 6C1T TITLE MBD2 IN COMPLEX WITH A PARTIALLY METHYLATED DNA COMPND MOL_ID: 1; COMPND 2 MOLECULE: METHYL-CPG-BINDING DOMAIN PROTEIN 2; COMPND 3 CHAIN: A, D; COMPND 4 SYNONYM: DEMETHYLASE,DMTASE,METHYL-CPG-BINDING PROTEIN MBD2; COMPND 5 ENGINEERED: YES; COMPND 6 MOL_ID: 2; COMPND 7 MOLECULE: 12-MER DNA; COMPND 8 CHAIN: B; COMPND 9 ENGINEERED: YES; COMPND 10 MOL_ID: 3; COMPND 11 MOLECULE: 12-MER DNA; COMPND 12 CHAIN: C; COMPND 13 ENGINEERED: YES SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS; SOURCE 3 ORGANISM_COMMON: HUMAN; SOURCE 4 ORGANISM_TAXID: 9606; SOURCE 5 GENE: MBD2; SOURCE 6 EXPRESSION_SYSTEM: ESCHERICHIA COLI; SOURCE 7 EXPRESSION_SYSTEM_TAXID: 562; SOURCE 8 EXPRESSION_SYSTEM_STRAIN: BL21(DE3)-V2R-RIL; SOURCE 9 EXPRESSION_SYSTEM_PLASMID: PET28-MHL; SOURCE 10 MOL_ID: 2; SOURCE 11 SYNTHETIC: YES; SOURCE 12 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 13 ORGANISM_TAXID: 32630; SOURCE 14 MOL_ID: 3; SOURCE 15 SYNTHETIC: YES; SOURCE 16 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT; SOURCE 17 ORGANISM_TAXID: 32630 KEYWDS MBD, DNA-BINDING, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS KEYWDS 2 CONSORTIUM, SGC, DNA BINDING PROTEIN-DNA COMPLEX EXPDTA X-RAY DIFFRACTION AUTHOR M.LEI,W.TEMPEL,C.H.ARROWSMITH,C.BOUNTRA,A.M.EDWARDS,J.MIN,STRUCTURAL AUTHOR 2 GENOMICS CONSORTIUM (SGC) REVDAT 3 23-MAY-18 6C1T 1 JRNL REVDAT 2 18-APR-18 6C1T 1 JRNL REVDAT 1 14-FEB-18 6C1T 0 JRNL AUTH K.LIU,C.XU,M.LEI,A.YANG,P.LOPPNAU,T.R.HUGHES,J.MIN JRNL TITL STRUCTURAL BASIS FOR THE ABILITY OF MBD DOMAINS TO BIND JRNL TITL 2 METHYL-CG AND TG SITES IN DNA. JRNL REF J. BIOL. CHEM. V. 293 7344 2018 JRNL REFN ESSN 1083-351X JRNL PMID 29567833 JRNL DOI 10.1074/JBC.RA118.001785 REMARK 2 REMARK 2 RESOLUTION. 1.84 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.8.0158 REMARK 3 AUTHORS : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,STEINER, REMARK 3 : NICHOLLS,WINN,LONG,VAGIN REMARK 3 REMARK 3 REFINEMENT TARGET : NULL REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 1.84 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 49.00 REMARK 3 DATA CUTOFF (SIGMA(F)) : 0.000 REMARK 3 COMPLETENESS FOR RANGE (%) : 99.0 REMARK 3 NUMBER OF REFLECTIONS : 21271 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : NULL REMARK 3 R VALUE (WORKING + TEST SET) : 0.215 REMARK 3 R VALUE (WORKING SET) : 0.214 REMARK 3 FREE R VALUE : 0.247 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.900 REMARK 3 FREE R VALUE TEST SET COUNT : 1095 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 1.84 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 1.89 REMARK 3 REFLECTION IN BIN (WORKING SET) : 1428 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 92.81 REMARK 3 BIN R VALUE (WORKING SET) : 0.3360 REMARK 3 BIN FREE R VALUE SET COUNT : 82 REMARK 3 BIN FREE R VALUE : 0.3680 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 996 REMARK 3 NUCLEIC ACID ATOMS : 487 REMARK 3 HETEROGEN ATOMS : 35 REMARK 3 SOLVENT ATOMS : 41 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 49.51 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -0.13000 REMARK 3 B22 (A**2) : 0.01000 REMARK 3 B33 (A**2) : 0.13000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : -0.06000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.129 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.126 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.114 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 7.995 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.959 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.951 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 1576 ; 0.014 ; 0.017 REMARK 3 BOND LENGTHS OTHERS (A): 1195 ; 0.002 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 2229 ; 1.758 ; 1.701 REMARK 3 BOND ANGLES OTHERS (DEGREES): 2771 ; 1.182 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 131 ; 6.071 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 38 ;29.368 ;21.579 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 157 ;11.697 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 8 ;20.662 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 216 ; 0.099 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 1434 ; 0.013 ; 0.021 REMARK 3 GENERAL PLANES OTHERS (A): 346 ; 0.002 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 531 ; 1.375 ; 2.957 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 530 ; 1.376 ; 2.953 REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 661 ; 2.027 ; 4.418 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : 4 REMARK 3 REMARK 3 TLS GROUP : 1 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : A 148 A 215 REMARK 3 ORIGIN FOR THE GROUP (A): -15.1745 26.9201 108.8401 REMARK 3 T TENSOR REMARK 3 T11: 0.1818 T22: 0.0948 REMARK 3 T33: 0.0158 T12: -0.0658 REMARK 3 T13: -0.0001 T23: -0.0019 REMARK 3 L TENSOR REMARK 3 L11: 2.8517 L22: 3.7358 REMARK 3 L33: 6.3125 L12: -0.9724 REMARK 3 L13: 1.3119 L23: -1.2599 REMARK 3 S TENSOR REMARK 3 S11: 0.0445 S12: 0.0091 S13: -0.2085 REMARK 3 S21: -0.2683 S22: 0.0849 S23: 0.0972 REMARK 3 S31: 0.3120 S32: -0.0897 S33: -0.1294 REMARK 3 REMARK 3 TLS GROUP : 2 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : B 1 B 12 REMARK 3 ORIGIN FOR THE GROUP (A): -15.9714 32.1378 124.1032 REMARK 3 T TENSOR REMARK 3 T11: 0.0940 T22: 0.1452 REMARK 3 T33: 0.0586 T12: -0.0233 REMARK 3 T13: 0.0348 T23: -0.0115 REMARK 3 L TENSOR REMARK 3 L11: 8.0348 L22: 3.9760 REMARK 3 L33: 1.8834 L12: 4.0273 REMARK 3 L13: 0.9462 L23: -0.3218 REMARK 3 S TENSOR REMARK 3 S11: -0.1763 S12: -0.1470 S13: -0.3687 REMARK 3 S21: -0.1475 S22: 0.0971 S23: -0.0461 REMARK 3 S31: 0.0775 S32: -0.1042 S33: 0.0792 REMARK 3 REMARK 3 TLS GROUP : 3 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : C 1 C 12 REMARK 3 ORIGIN FOR THE GROUP (A): -16.1925 33.4383 123.3795 REMARK 3 T TENSOR REMARK 3 T11: 0.1319 T22: 0.1569 REMARK 3 T33: 0.0091 T12: -0.0570 REMARK 3 T13: 0.0013 T23: -0.0013 REMARK 3 L TENSOR REMARK 3 L11: 6.7615 L22: 3.8020 REMARK 3 L33: 0.7873 L12: 3.9007 REMARK 3 L13: 0.8079 L23: -0.1614 REMARK 3 S TENSOR REMARK 3 S11: -0.0883 S12: -0.1743 S13: 0.2003 REMARK 3 S21: -0.0173 S22: 0.0538 S23: 0.1574 REMARK 3 S31: -0.0071 S32: -0.1591 S33: 0.0345 REMARK 3 REMARK 3 TLS GROUP : 4 REMARK 3 NUMBER OF COMPONENTS GROUP : 1 REMARK 3 COMPONENTS C SSSEQI TO C SSSEQI REMARK 3 RESIDUE RANGE : D 149 D 214 REMARK 3 ORIGIN FOR THE GROUP (A): -6.0204 43.8811 138.4985 REMARK 3 T TENSOR REMARK 3 T11: 0.2923 T22: 0.5024 REMARK 3 T33: 0.1006 T12: -0.0733 REMARK 3 T13: -0.0502 T23: -0.0461 REMARK 3 L TENSOR REMARK 3 L11: 2.2468 L22: 5.3269 REMARK 3 L33: 7.1232 L12: 0.0718 REMARK 3 L13: -1.6750 L23: -2.9222 REMARK 3 S TENSOR REMARK 3 S11: -0.0129 S12: -0.8720 S13: 0.2677 REMARK 3 S21: 0.8714 S22: -0.0727 S23: -0.0660 REMARK 3 S31: -0.3416 S32: 0.2516 S33: 0.0857 REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : NULL REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: THE IDENTITY OF THE 'SULFATE' NEAR SER REMARK 3 -183 IS UNCLEAR. SIMILAR DENSITY WAS ALSO OBSERVED IN ANOTHER REMARK 3 MBD2-DNA COMPLEX CRYSTAL WHERE THE CRYSTALLIZATION BUFFER DID REMARK 3 NOT INCLUDE SULFATE. REMARK 4 REMARK 4 6C1T COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 09-JAN-18. REMARK 100 THE DEPOSITION ID IS D_1000230207. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : 17-SEP-17 REMARK 200 TEMPERATURE (KELVIN) : 100 REMARK 200 PH : 5.5 REMARK 200 NUMBER OF CRYSTALS USED : 1 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y REMARK 200 RADIATION SOURCE : CLSI REMARK 200 BEAMLINE : 08ID-1 REMARK 200 X-RAY GENERATOR MODEL : NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M REMARK 200 WAVELENGTH OR RANGE (A) : 0.97949 REMARK 200 MONOCHROMATOR : NULL REMARK 200 OPTICS : NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL REMARK 200 DETECTOR MANUFACTURER : DECTRIS PILATUS3 6M REMARK 200 INTENSITY-INTEGRATION SOFTWARE : XDS REMARK 200 DATA SCALING SOFTWARE : AIMLESS 0.5.32 REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 22367 REMARK 200 RESOLUTION RANGE HIGH (A) : 1.840 REMARK 200 RESOLUTION RANGE LOW (A) : 49.420 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : NULL REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 99.0 REMARK 200 DATA REDUNDANCY : 3.200 REMARK 200 R MERGE (I) : 0.05200 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 9.8000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.84 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 1.88 REMARK 200 COMPLETENESS FOR SHELL (%) : 91.3 REMARK 200 DATA REDUNDANCY IN SHELL : 3.00 REMARK 200 R MERGE FOR SHELL (I) : 1.24400 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : NULL REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: CURRENTLY UNPUBLISHED MODEL OF MBD2-DNA COMPLEX REMARK 200 REMARK 200 REMARK: NULL REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 53.00 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.62 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 27% PEG-3350, 0.1 M BIS-TRIS, 0.15 M REMARK 280 AMMONIUM SULFATE, PH 5.5, VAPOR DIFFUSION, SITTING DROP, REMARK 280 TEMPERATURE 291K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,Y+1/2,Z REMARK 290 4555 -X+1/2,Y+1/2,-Z REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 35.73650 REMARK 290 SMTRY2 3 0.000000 1.000000 0.000000 18.46650 REMARK 290 SMTRY3 3 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 35.73650 REMARK 290 SMTRY2 4 0.000000 1.000000 0.000000 18.46650 REMARK 290 SMTRY3 4 0.000000 0.000000 -1.000000 0.00000 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TETRAMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 TOTAL BURIED SURFACE AREA: 4890 ANGSTROM**2 REMARK 350 SURFACE AREA OF THE COMPLEX: 10850 ANGSTROM**2 REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -38.0 KCAL/MOL REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 GLY A 142 REMARK 465 ALA A 143 REMARK 465 THR A 144 REMARK 465 GLU A 145 REMARK 465 SER A 146 REMARK 465 GLY A 147 REMARK 465 SER A 216 REMARK 465 LYS A 217 REMARK 465 LEU A 218 REMARK 465 GLN A 219 REMARK 465 LYS A 220 REMARK 465 GLY D 142 REMARK 465 ALA D 143 REMARK 465 THR D 144 REMARK 465 GLU D 145 REMARK 465 SER D 146 REMARK 465 GLY D 147 REMARK 465 LYS D 148 REMARK 465 PRO D 215 REMARK 465 SER D 216 REMARK 465 LYS D 217 REMARK 465 LEU D 218 REMARK 465 GLN D 219 REMARK 465 LYS D 220 REMARK 470 REMARK 470 MISSING ATOM REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 470 I=INSERTION CODE): REMARK 470 M RES CSSEQI ATOMS REMARK 470 LYS A 148 CG CD CE NZ REMARK 470 LYS A 161 NZ REMARK 470 LYS A 167 CD CE NZ REMARK 470 SER A 171 OG REMARK 470 LYS A 174 CD CE NZ REMARK 470 ARG A 195 CD NE CZ NH1 NH2 REMARK 470 LYS A 212 CD CE NZ REMARK 470 MET A 214 SD CE REMARK 470 PRO A 215 CA C O CB CG CD REMARK 470 MET D 150 CG SD CE REMARK 470 ASP D 151 CG OD1 OD2 REMARK 470 LYS D 160 CG CD CE NZ REMARK 470 LYS D 167 CD CE NZ REMARK 470 LYS D 174 CE NZ REMARK 470 SER D 183 OG REMARK 470 LYS D 185 CG CD CE NZ REMARK 470 LYS D 186 CG CD CE NZ REMARK 470 ARG D 195 CG CD NE CZ NH1 NH2 REMARK 470 ASN D 199 CG OD1 ND2 REMARK 470 THR D 200 OG1 CG2 REMARK 470 LYS D 212 CD CE NZ REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: COVALENT BOND ANGLES REMARK 500 REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1) REMARK 500 REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999 REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996 REMARK 500 REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3 REMARK 500 DA B 5 O5' - P - OP2 ANGL. DEV. = -9.8 DEGREES REMARK 500 DC B 8 O5' - P - OP2 ANGL. DEV. = -5.6 DEGREES REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: PLANAR GROUPS REMARK 500 REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS REMARK 500 AN RMSD GREATER THAN THIS VALUE REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 M RES CSSEQI RMS TYPE REMARK 500 DT B 9 0.07 SIDE CHAIN REMARK 500 REMARK 500 REMARK: NULL REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue SO4 A 301 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: binding site for residue GOL C 106 DBREF 6C1T A 143 220 UNP Q9UBB5 MBD2_HUMAN 143 220 DBREF 6C1T B 1 12 PDB 6C1T 6C1T 1 12 DBREF 6C1T C 1 12 PDB 6C1T 6C1T 1 12 DBREF 6C1T D 143 220 UNP Q9UBB5 MBD2_HUMAN 143 220 SEQADV 6C1T GLY A 142 UNP Q9UBB5 EXPRESSION TAG SEQADV 6C1T GLY D 142 UNP Q9UBB5 EXPRESSION TAG SEQRES 1 A 79 GLY ALA THR GLU SER GLY LYS ARG MET ASP CYS PRO ALA SEQRES 2 A 79 LEU PRO PRO GLY TRP LYS LYS GLU GLU VAL ILE ARG LYS SEQRES 3 A 79 SER GLY LEU SER ALA GLY LYS SER ASP VAL TYR TYR PHE SEQRES 4 A 79 SER PRO SER GLY LYS LYS PHE ARG SER LYS PRO GLN LEU SEQRES 5 A 79 ALA ARG TYR LEU GLY ASN THR VAL ASP LEU SER SER PHE SEQRES 6 A 79 ASP PHE ARG THR GLY LYS MET MET PRO SER LYS LEU GLN SEQRES 7 A 79 LYS SEQRES 1 B 12 DG DC DC DT DA 5CM DA DC DT DC DC DG SEQRES 1 C 12 DC DG DG DA DG DT DG DT DA DG DG DC SEQRES 1 D 79 GLY ALA THR GLU SER GLY LYS ARG MET ASP CYS PRO ALA SEQRES 2 D 79 LEU PRO PRO GLY TRP LYS LYS GLU GLU VAL ILE ARG LYS SEQRES 3 D 79 SER GLY LEU SER ALA GLY LYS SER ASP VAL TYR TYR PHE SEQRES 4 D 79 SER PRO SER GLY LYS LYS PHE ARG SER LYS PRO GLN LEU SEQRES 5 D 79 ALA ARG TYR LEU GLY ASN THR VAL ASP LEU SER SER PHE SEQRES 6 D 79 ASP PHE ARG THR GLY LYS MET MET PRO SER LYS LEU GLN SEQRES 7 D 79 LYS HET 5CM B 6 20 HET SO4 A 301 5 HET UNX A 302 1 HET UNX A 303 1 HET UNX A 304 1 HET UNX A 305 1 HET UNX A 306 1 HET UNX A 307 1 HET UNX A 308 1 HET UNX A 309 1 HET UNX A 310 1 HET UNX A 311 1 HET UNX A 312 1 HET UNX A 313 1 HET UNX A 314 1 HET UNX B 101 1 HET UNX B 102 1 HET UNX B 103 1 HET UNX C 101 1 HET UNX C 102 1 HET UNX C 103 1 HET UNX C 104 1 HET UNX C 105 1 HET GOL C 106 6 HET UNX D 301 1 HET UNX D 302 1 HET UNX D 303 1 HETNAM 5CM 5-METHYL-2'-DEOXY-CYTIDINE-5'-MONOPHOSPHATE HETNAM SO4 SULFATE ION HETNAM UNX UNKNOWN ATOM OR ION HETNAM GOL GLYCEROL HETSYN GOL GLYCERIN; PROPANE-1,2,3-TRIOL FORMUL 2 5CM C10 H16 N3 O7 P FORMUL 5 SO4 O4 S 2- FORMUL 6 UNX 24(X) FORMUL 27 GOL C3 H8 O3 FORMUL 31 HOH *41(H2 O) HELIX 1 AA1 SER A 189 GLY A 198 1 10 HELIX 2 AA2 ASN A 199 VAL A 201 5 3 HELIX 3 AA3 SER D 189 GLY D 198 1 10 HELIX 4 AA4 ASN D 199 VAL D 201 5 3 SHEET 1 AA1 4 MET A 150 ASP A 151 0 SHEET 2 AA1 4 LYS A 160 ILE A 165 -1 O LYS A 161 N MET A 150 SHEET 3 AA1 4 SER A 175 PHE A 180 -1 O TYR A 178 N GLU A 162 SHEET 4 AA1 4 LYS A 186 PHE A 187 -1 O PHE A 187 N TYR A 179 SHEET 1 AA2 2 PHE A 206 ASP A 207 0 SHEET 2 AA2 2 LYS A 212 MET A 213 -1 O LYS A 212 N ASP A 207 SHEET 1 AA3 4 MET D 150 ASP D 151 0 SHEET 2 AA3 4 LYS D 160 ILE D 165 -1 O LYS D 161 N MET D 150 SHEET 3 AA3 4 SER D 175 PHE D 180 -1 O TYR D 178 N GLU D 162 SHEET 4 AA3 4 LYS D 186 PHE D 187 -1 O PHE D 187 N TYR D 179 SHEET 1 AA4 2 PHE D 206 ASP D 207 0 SHEET 2 AA4 2 LYS D 212 MET D 213 -1 O LYS D 212 N ASP D 207 LINK O3' DA B 5 P 5CM B 6 1555 1555 1.58 LINK O3' 5CM B 6 P DA B 7 1555 1555 1.59 SITE 1 AC1 5 SER A 181 PRO A 182 SER A 183 LYS A 185 SITE 2 AC1 5 TYR A 196 SITE 1 AC2 8 DC C 1 DG C 11 HOH C 201 HOH C 204 SITE 2 AC2 8 ILE D 165 ARG D 166 LYS D 167 HOH D 402 CRYST1 71.473 36.933 104.076 90.00 108.25 90.00 C 1 2 1 8 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.013991 0.000000 0.004613 0.00000 SCALE2 0.000000 0.027076 0.000000 0.00000 SCALE3 0.000000 0.000000 0.010117 0.00000 ATOM 1 N LYS A 148 -5.377 20.240 112.102 1.00 57.45 N ANISOU 1 N LYS A 148 8071 7333 6423 874 84 -75 N ATOM 2 CA LYS A 148 -4.828 20.274 110.729 1.00 57.24 C ANISOU 2 CA LYS A 148 8009 7403 6337 1022 216 -160 C ATOM 3 C LYS A 148 -5.751 21.126 109.855 1.00 53.39 C ANISOU 3 C LYS A 148 7562 6886 5835 764 265 -198 C ATOM 4 O LYS A 148 -6.986 21.103 110.018 1.00 50.59 O ANISOU 4 O LYS A 148 7379 6337 5503 561 184 -193 O ATOM 5 CB LYS A 148 -4.667 18.852 110.213 1.00 63.45 C ANISOU 5 CB LYS A 148 9091 7974 7043 1333 203 -236 C ATOM 6 N ARG A 149 -5.166 21.955 108.991 1.00 53.34 N ANISOU 6 N ARG A 149 7367 7103 5794 757 396 -207 N ATOM 7 CA ARG A 149 -5.950 22.707 108.002 1.00 50.89 C ANISOU 7 CA ARG A 149 7130 6764 5442 565 444 -237 C ATOM 8 C ARG A 149 -6.287 21.841 106.778 1.00 50.09 C ANISOU 8 C ARG A 149 7317 6506 5209 724 473 -348 C ATOM 9 O ARG A 149 -5.446 21.584 105.938 1.00 52.83 O ANISOU 9 O ARG A 149 7645 6983 5445 961 604 -392 O ATOM 10 CB ARG A 149 -5.226 23.980 107.553 1.00 52.85 C ANISOU 10 CB ARG A 149 7101 7288 5690 460 566 -174 C ATOM 11 CG ARG A 149 -5.004 24.978 108.682 1.00 51.23 C ANISOU 11 CG ARG A 149 6674 7188 5602 251 491 -88 C ATOM 12 CD ARG A 149 -4.753 26.364 108.137 1.00 53.76 C ANISOU 12 CD ARG A 149 6839 7656 5930 38 561 -23 C ATOM 13 NE ARG A 149 -4.509 27.283 109.233 1.00 53.68 N ANISOU 13 NE ARG A 149 6677 7698 6019 -158 452 35 N ATOM 14 CZ ARG A 149 -4.220 28.576 109.110 1.00 56.08 C ANISOU 14 CZ ARG A 149 6864 8084 6358 -391 451 104 C ATOM 15 NH1 ARG A 149 -4.147 29.175 107.934 1.00 56.10 N ANISOU 15 NH1 ARG A 149 6862 8144 6308 -474 572 152 N ATOM 16 NH2 ARG A 149 -4.018 29.294 110.215 1.00 60.90 N ANISOU 16 NH2 ARG A 149 7399 8695 7043 -553 308 127 N ATOM 17 N MET A 150 -7.547 21.457 106.656 1.00 46.96 N ANISOU 17 N MET A 150 7178 5850 4812 583 348 -390 N ATOM 18 CA MET A 150 -7.970 20.495 105.626 1.00 47.80 C ANISOU 18 CA MET A 150 7625 5742 4793 703 302 -512 C ATOM 19 C MET A 150 -8.689 21.270 104.556 1.00 44.59 C ANISOU 19 C MET A 150 7263 5369 4308 539 316 -539 C ATOM 20 O MET A 150 -9.534 22.112 104.849 1.00 42.60 O ANISOU 20 O MET A 150 6910 5136 4140 277 260 -469 O ATOM 21 CB MET A 150 -8.946 19.490 106.212 1.00 48.72 C ANISOU 21 CB MET A 150 8001 5536 4972 597 106 -516 C ATOM 22 CG MET A 150 -8.407 18.718 107.430 1.00 49.02 C ANISOU 22 CG MET A 150 8034 5501 5088 728 61 -454 C ATOM 23 SD MET A 150 -6.941 17.764 107.009 1.00 56.51 S ANISOU 23 SD MET A 150 9084 6468 5917 1218 152 -550 S ATOM 24 CE MET A 150 -7.497 16.746 105.630 1.00 56.81 C ANISOU 24 CE MET A 150 9623 6176 5783 1336 65 -735 C ATOM 25 N ASP A 151 -8.408 20.940 103.317 1.00 45.18 N ANISOU 25 N ASP A 151 7521 5444 4202 722 380 -644 N ATOM 26 CA ASP A 151 -9.255 21.441 102.241 1.00 44.82 C ANISOU 26 CA ASP A 151 7608 5373 4048 579 340 -682 C ATOM 27 C ASP A 151 -10.724 21.126 102.490 1.00 42.60 C ANISOU 27 C ASP A 151 7489 4844 3851 319 101 -688 C ATOM 28 O ASP A 151 -11.048 20.050 102.990 1.00 44.25 O ANISOU 28 O ASP A 151 7881 4816 4115 317 -39 -722 O ATOM 29 CB ASP A 151 -8.780 20.894 100.923 1.00 47.12 C ANISOU 29 CB ASP A 151 8149 5664 4088 851 419 -817 C ATOM 30 CG ASP A 151 -7.441 21.485 100.531 1.00 49.88 C ANISOU 30 CG ASP A 151 8251 6358 4342 1059 696 -759 C ATOM 31 OD1 ASP A 151 -7.334 22.726 100.572 1.00 52.33 O ANISOU 31 OD1 ASP A 151 8289 6881 4712 867 789 -624 O ATOM 32 OD2 ASP A 151 -6.510 20.758 100.180 1.00 50.17 O ANISOU 32 OD2 ASP A 151 8356 6462 4243 1406 820 -834 O ATOM 33 N CYS A 152 -11.601 22.088 102.203 1.00 39.67 N ANISOU 33 N CYS A 152 7029 4541 3501 96 55 -630 N ATOM 34 CA CYS A 152 -13.030 21.865 102.335 1.00 41.68 C ANISOU 34 CA CYS A 152 7370 4636 3830 -147 -163 -614 C ATOM 35 C CYS A 152 -13.573 21.824 100.894 1.00 43.47 C ANISOU 35 C CYS A 152 7834 4811 3869 -151 -262 -713 C ATOM 36 O CYS A 152 -13.795 22.890 100.298 1.00 43.18 O ANISOU 36 O CYS A 152 7701 4934 3771 -200 -214 -667 O ATOM 37 CB CYS A 152 -13.701 22.968 103.135 1.00 39.96 C ANISOU 37 CB CYS A 152 6867 4552 3762 -348 -159 -474 C ATOM 38 SG CYS A 152 -15.471 22.680 103.338 1.00 44.61 S ANISOU 38 SG CYS A 152 7470 5032 4447 -626 -401 -417 S ATOM 39 N PRO A 153 -13.752 20.618 100.341 1.00 47.67 N ANISOU 39 N PRO A 153 8710 5106 4296 -91 -414 -849 N ATOM 40 CA PRO A 153 -14.078 20.545 98.897 1.00 48.80 C ANISOU 40 CA PRO A 153 9130 5207 4203 -45 -510 -973 C ATOM 41 C PRO A 153 -15.353 21.240 98.481 1.00 49.64 C ANISOU 41 C PRO A 153 9164 5368 4327 -303 -685 -910 C ATOM 42 O PRO A 153 -15.443 21.678 97.344 1.00 49.88 O ANISOU 42 O PRO A 153 9319 5476 4155 -242 -696 -962 O ATOM 43 CB PRO A 153 -14.187 19.050 98.632 1.00 52.02 C ANISOU 43 CB PRO A 153 9953 5282 4528 18 -707 -1135 C ATOM 44 CG PRO A 153 -13.344 18.420 99.689 1.00 51.95 C ANISOU 44 CG PRO A 153 9894 5200 4642 166 -596 -1109 C ATOM 45 CD PRO A 153 -13.487 19.273 100.899 1.00 48.48 C ANISOU 45 CD PRO A 153 9024 4951 4442 -12 -500 -911 C ATOM 46 N ALA A 154 -16.359 21.310 99.348 1.00 48.36 N ANISOU 46 N ALA A 154 8807 5184 4384 -568 -824 -793 N ATOM 47 CA ALA A 154 -17.605 22.009 98.978 1.00 50.61 C ANISOU 47 CA ALA A 154 8966 5569 4692 -776 -989 -716 C ATOM 48 C ALA A 154 -17.539 23.546 98.952 1.00 48.34 C ANISOU 48 C ALA A 154 8416 5540 4411 -729 -822 -601 C ATOM 49 O ALA A 154 -18.469 24.176 98.443 1.00 49.20 O ANISOU 49 O ALA A 154 8463 5737 4491 -824 -953 -550 O ATOM 50 CB ALA A 154 -18.758 21.560 99.852 1.00 52.51 C ANISOU 50 CB ALA A 154 9054 5749 5148 -1061 -1181 -608 C ATOM 51 N LEU A 155 -16.471 24.154 99.459 1.00 44.33 N ANISOU 51 N LEU A 155 7768 5141 3933 -589 -564 -557 N ATOM 52 CA LEU A 155 -16.292 25.600 99.370 1.00 42.98 C ANISOU 52 CA LEU A 155 7422 5154 3753 -559 -423 -453 C ATOM 53 C LEU A 155 -15.394 25.853 98.134 1.00 45.84 C ANISOU 53 C LEU A 155 7966 5582 3870 -390 -291 -507 C ATOM 54 O LEU A 155 -14.872 24.896 97.574 1.00 43.79 O ANISOU 54 O LEU A 155 7929 5242 3464 -260 -281 -633 O ATOM 55 CB LEU A 155 -15.676 26.153 100.663 1.00 40.65 C ANISOU 55 CB LEU A 155 6879 4934 3632 -554 -255 -363 C ATOM 56 CG LEU A 155 -16.560 26.078 101.911 1.00 40.43 C ANISOU 56 CG LEU A 155 6665 4892 3803 -689 -342 -287 C ATOM 57 CD1 LEU A 155 -15.831 26.642 103.115 1.00 37.99 C ANISOU 57 CD1 LEU A 155 6173 4651 3609 -652 -185 -225 C ATOM 58 CD2 LEU A 155 -17.868 26.834 101.709 1.00 41.80 C ANISOU 58 CD2 LEU A 155 6739 5142 3999 -781 -471 -211 C ATOM 59 N PRO A 156 -15.252 27.124 97.683 1.00 47.00 N ANISOU 59 N PRO A 156 8044 5864 3949 -380 -190 -404 N ATOM 60 CA PRO A 156 -14.427 27.397 96.485 1.00 48.19 C ANISOU 60 CA PRO A 156 8355 6109 3843 -239 -40 -413 C ATOM 61 C PRO A 156 -12.959 27.019 96.720 1.00 48.07 C ANISOU 61 C PRO A 156 8279 6177 3807 -92 208 -433 C ATOM 62 O PRO A 156 -12.588 26.713 97.872 1.00 45.15 O ANISOU 62 O PRO A 156 7734 5781 3638 -113 246 -427 O ATOM 63 CB PRO A 156 -14.574 28.909 96.305 1.00 49.01 C ANISOU 63 CB PRO A 156 8359 6311 3949 -310 14 -249 C ATOM 64 CG PRO A 156 -15.871 29.250 96.973 1.00 47.68 C ANISOU 64 CG PRO A 156 8075 6079 3960 -437 -191 -210 C ATOM 65 CD PRO A 156 -15.876 28.363 98.184 1.00 46.82 C ANISOU 65 CD PRO A 156 7834 5900 4055 -483 -214 -269 C ATOM 66 N PRO A 157 -12.129 27.017 95.672 1.00 48.63 N ANISOU 66 N PRO A 157 8476 6372 3627 73 380 -445 N ATOM 67 CA PRO A 157 -10.773 26.482 95.795 1.00 50.00 C ANISOU 67 CA PRO A 157 8576 6666 3755 267 614 -471 C ATOM 68 C PRO A 157 -9.987 27.226 96.808 1.00 49.80 C ANISOU 68 C PRO A 157 8203 6769 3947 167 762 -323 C ATOM 69 O PRO A 157 -10.104 28.457 96.875 1.00 50.16 O ANISOU 69 O PRO A 157 8128 6873 4056 -8 785 -172 O ATOM 70 CB PRO A 157 -10.173 26.699 94.401 1.00 53.96 C ANISOU 70 CB PRO A 157 9232 7347 3923 437 798 -454 C ATOM 71 CG PRO A 157 -11.342 26.623 93.489 1.00 55.56 C ANISOU 71 CG PRO A 157 9745 7415 3949 401 569 -534 C ATOM 72 CD PRO A 157 -12.483 27.262 94.254 1.00 52.36 C ANISOU 72 CD PRO A 157 9204 6884 3803 134 345 -458 C ATOM 73 N GLY A 158 -9.217 26.511 97.629 1.00 47.77 N ANISOU 73 N GLY A 158 7810 6534 3805 274 830 -365 N ATOM 74 CA GLY A 158 -8.315 27.138 98.554 1.00 45.74 C ANISOU 74 CA GLY A 158 7220 6429 3729 192 956 -234 C ATOM 75 C GLY A 158 -8.874 27.297 99.956 1.00 43.98 C ANISOU 75 C GLY A 158 6873 6064 3773 17 792 -220 C ATOM 76 O GLY A 158 -8.096 27.602 100.833 1.00 43.13 O ANISOU 76 O GLY A 158 6524 6059 3805 -25 856 -147 O ATOM 77 N TRP A 159 -10.193 27.135 100.148 1.00 40.58 N ANISOU 77 N TRP A 159 6589 5433 3396 -82 585 -277 N ATOM 78 CA TRP A 159 -10.818 27.270 101.461 1.00 39.13 C ANISOU 78 CA TRP A 159 6291 5148 3429 -222 455 -253 C ATOM 79 C TRP A 159 -10.470 26.070 102.278 1.00 38.52 C ANISOU 79 C TRP A 159 6205 5002 3428 -116 429 -323 C ATOM 80 O TRP A 159 -10.469 24.944 101.738 1.00 39.47 O ANISOU 80 O TRP A 159 6526 5025 3444 29 397 -431 O ATOM 81 CB TRP A 159 -12.333 27.387 101.314 1.00 38.25 C ANISOU 81 CB TRP A 159 6296 4903 3331 -338 266 -268 C ATOM 82 CG TRP A 159 -12.733 28.836 101.044 1.00 37.89 C ANISOU 82 CG TRP A 159 6205 4909 3281 -446 267 -163 C ATOM 83 CD1 TRP A 159 -12.874 29.431 99.826 1.00 39.62 C ANISOU 83 CD1 TRP A 159 6551 5168 3336 -438 285 -127 C ATOM 84 CD2 TRP A 159 -13.017 29.827 102.007 1.00 36.48 C ANISOU 84 CD2 TRP A 159 5892 4724 3246 -548 241 -84 C ATOM 85 NE1 TRP A 159 -13.217 30.764 99.972 1.00 39.77 N ANISOU 85 NE1 TRP A 159 6522 5185 3403 -535 267 -16 N ATOM 86 CE2 TRP A 159 -13.334 31.025 101.311 1.00 38.98 C ANISOU 86 CE2 TRP A 159 6272 5046 3490 -594 235 -2 C ATOM 87 CE3 TRP A 159 -13.101 29.823 103.415 1.00 35.06 C ANISOU 87 CE3 TRP A 159 5577 4519 3225 -586 210 -78 C ATOM 88 CZ2 TRP A 159 -13.657 32.238 101.980 1.00 37.14 C ANISOU 88 CZ2 TRP A 159 5992 4769 3350 -662 197 71 C ATOM 89 CZ3 TRP A 159 -13.443 31.012 104.053 1.00 34.08 C ANISOU 89 CZ3 TRP A 159 5400 4378 3170 -648 181 -16 C ATOM 90 CH2 TRP A 159 -13.704 32.207 103.339 1.00 35.04 C ANISOU 90 CH2 TRP A 159 5606 4479 3227 -679 171 50 C ATOM 91 N LYS A 160 -10.168 26.265 103.574 1.00 36.97 N ANISOU 91 N LYS A 160 5822 4830 3394 -172 425 -267 N ATOM 92 CA LYS A 160 -9.793 25.160 104.460 1.00 38.04 C ANISOU 92 CA LYS A 160 5952 4900 3599 -62 392 -306 C ATOM 93 C LYS A 160 -10.587 25.242 105.762 1.00 36.77 C ANISOU 93 C LYS A 160 5731 4655 3584 -205 274 -258 C ATOM 94 O LYS A 160 -11.152 26.282 106.035 1.00 34.60 O ANISOU 94 O LYS A 160 5375 4414 3354 -345 251 -202 O ATOM 95 CB LYS A 160 -8.320 25.176 104.759 1.00 40.88 C ANISOU 95 CB LYS A 160 6118 5443 3968 74 528 -273 C ATOM 96 CG LYS A 160 -7.472 25.213 103.510 1.00 44.35 C ANISOU 96 CG LYS A 160 6557 6044 4248 228 696 -286 C ATOM 97 CD LYS A 160 -6.134 24.643 103.752 1.00 47.35 C ANISOU 97 CD LYS A 160 6774 6594 4619 458 814 -278 C ATOM 98 CE LYS A 160 -5.287 24.956 102.545 1.00 51.19 C ANISOU 98 CE LYS A 160 7184 7323 4939 584 1026 -246 C ATOM 99 NZ LYS A 160 -4.194 23.998 102.523 1.00 55.04 N ANISOU 99 NZ LYS A 160 7596 7952 5363 925 1141 -284 N ATOM 100 N LYS A 161 -10.702 24.095 106.447 1.00 39.24 N ANISOU 100 N LYS A 161 6126 4842 3940 -147 200 -278 N ATOM 101 CA LYS A 161 -11.422 23.916 107.739 1.00 38.51 C ANISOU 101 CA LYS A 161 5995 4682 3955 -258 109 -211 C ATOM 102 C LYS A 161 -10.434 23.274 108.737 1.00 41.45 C ANISOU 102 C LYS A 161 6315 5068 4363 -121 126 -190 C ATOM 103 O LYS A 161 -9.572 22.471 108.376 1.00 40.21 O ANISOU 103 O LYS A 161 6231 4887 4160 72 158 -241 O ATOM 104 CB LYS A 161 -12.670 23.026 107.535 1.00 42.11 C ANISOU 104 CB LYS A 161 6630 4950 4417 -366 -24 -215 C ATOM 105 CG LYS A 161 -13.426 22.494 108.778 1.00 44.45 C ANISOU 105 CG LYS A 161 6909 5177 4804 -481 -102 -115 C ATOM 106 CD LYS A 161 -14.435 21.387 108.471 1.00 47.03 C ANISOU 106 CD LYS A 161 7422 5301 5144 -618 -250 -100 C ATOM 107 CE LYS A 161 -14.274 20.124 109.330 1.00 50.68 C ANISOU 107 CE LYS A 161 8027 5581 5645 -608 -312 -39 C ATOM 108 N GLU A 162 -10.528 23.689 110.007 1.00 38.93 N ANISOU 108 N GLU A 162 5874 4808 4109 -190 103 -116 N ATOM 109 CA GLU A 162 -9.755 23.095 111.058 1.00 40.76 C ANISOU 109 CA GLU A 162 6070 5053 4362 -73 83 -79 C ATOM 110 C GLU A 162 -10.645 22.969 112.270 1.00 39.04 C ANISOU 110 C GLU A 162 5875 4786 4173 -183 18 8 C ATOM 111 O GLU A 162 -11.372 23.930 112.619 1.00 37.27 O ANISOU 111 O GLU A 162 5569 4636 3953 -310 28 37 O ATOM 112 CB GLU A 162 -8.603 24.028 111.475 1.00 43.71 C ANISOU 112 CB GLU A 162 6219 5638 4749 -37 128 -68 C ATOM 113 CG GLU A 162 -7.844 23.529 112.678 1.00 44.58 C ANISOU 113 CG GLU A 162 6269 5795 4873 77 72 -22 C ATOM 114 CD GLU A 162 -6.463 24.116 112.870 1.00 49.76 C ANISOU 114 CD GLU A 162 6687 6674 5546 139 86 -14 C ATOM 115 OE1 GLU A 162 -6.188 25.214 112.325 1.00 54.02 O ANISOU 115 OE1 GLU A 162 7094 7332 6099 16 135 -23 O ATOM 116 OE2 GLU A 162 -5.648 23.449 113.603 1.00 54.41 O ANISOU 116 OE2 GLU A 162 7218 7320 6135 303 31 17 O ATOM 117 N GLU A 163 -10.526 21.827 112.919 1.00 40.06 N ANISOU 117 N GLU A 163 6120 4798 4303 -106 -35 59 N ATOM 118 CA GLU A 163 -11.252 21.540 114.135 1.00 43.16 C ANISOU 118 CA GLU A 163 6543 5159 4696 -195 -77 178 C ATOM 119 C GLU A 163 -10.224 21.498 115.277 1.00 41.93 C ANISOU 119 C GLU A 163 6323 5097 4508 -50 -98 216 C ATOM 120 O GLU A 163 -9.215 20.835 115.121 1.00 44.96 O ANISOU 120 O GLU A 163 6741 5448 4890 133 -121 189 O ATOM 121 CB GLU A 163 -11.948 20.191 114.020 1.00 47.54 C ANISOU 121 CB GLU A 163 7320 5475 5267 -257 -150 244 C ATOM 122 CG GLU A 163 -12.872 19.995 115.191 1.00 51.24 C ANISOU 122 CG GLU A 163 7784 5954 5730 -401 -162 410 C ATOM 123 CD GLU A 163 -13.592 18.673 115.193 1.00 57.62 C ANISOU 123 CD GLU A 163 8807 6517 6567 -533 -250 522 C ATOM 124 OE1 GLU A 163 -13.823 18.121 116.291 1.00 61.60 O ANISOU 124 OE1 GLU A 163 9368 6990 7047 -576 -262 686 O ATOM 125 OE2 GLU A 163 -13.949 18.209 114.099 1.00 60.91 O ANISOU 125 OE2 GLU A 163 9353 6767 7020 -610 -318 454 O ATOM 126 N VAL A 164 -10.511 22.171 116.400 1.00 40.19 N ANISOU 126 N VAL A 164 6024 4999 4246 -108 -98 276 N ATOM 127 CA VAL A 164 -9.572 22.310 117.548 1.00 38.21 C ANISOU 127 CA VAL A 164 5714 4863 3938 10 -153 302 C ATOM 128 C VAL A 164 -10.314 21.855 118.770 1.00 38.20 C ANISOU 128 C VAL A 164 5818 4838 3857 -23 -167 438 C ATOM 129 O VAL A 164 -11.349 22.407 119.141 1.00 36.50 O ANISOU 129 O VAL A 164 5586 4683 3597 -138 -110 479 O ATOM 130 CB VAL A 164 -9.072 23.784 117.758 1.00 37.90 C ANISOU 130 CB VAL A 164 5510 5007 3882 -28 -161 220 C ATOM 131 CG1 VAL A 164 -8.069 23.899 118.914 1.00 38.28 C ANISOU 131 CG1 VAL A 164 5502 5176 3866 69 -267 237 C ATOM 132 CG2 VAL A 164 -8.432 24.310 116.482 1.00 40.00 C ANISOU 132 CG2 VAL A 164 5660 5314 4223 -43 -121 127 C ATOM 133 N ILE A 165 -9.710 20.922 119.457 1.00 40.30 N ANISOU 133 N ILE A 165 6178 5048 4083 107 -236 518 N ATOM 134 CA ILE A 165 -10.203 20.401 120.713 1.00 41.82 C ANISOU 134 CA ILE A 165 6489 5229 4169 99 -252 679 C ATOM 135 C ILE A 165 -9.830 21.373 121.846 1.00 42.10 C ANISOU 135 C ILE A 165 6443 5479 4074 154 -285 657 C ATOM 136 O ILE A 165 -8.674 21.726 121.975 1.00 41.31 O ANISOU 136 O ILE A 165 6252 5472 3971 267 -379 574 O ATOM 137 CB ILE A 165 -9.555 19.027 121.036 1.00 45.02 C ANISOU 137 CB ILE A 165 7071 5468 4563 256 -344 779 C ATOM 138 CG1 ILE A 165 -9.702 18.032 119.872 1.00 47.34 C ANISOU 138 CG1 ILE A 165 7515 5503 4969 251 -353 756 C ATOM 139 CG2 ILE A 165 -10.159 18.442 122.307 1.00 47.75 C ANISOU 139 CG2 ILE A 165 7570 5788 4784 217 -349 987 C ATOM 140 CD1 ILE A 165 -11.120 17.886 119.362 1.00 47.35 C ANISOU 140 CD1 ILE A 165 7580 5389 5021 -15 -296 813 C ATOM 141 N ARG A 166 -10.814 21.738 122.671 1.00 42.24 N ANISOU 141 N ARG A 166 6497 5580 3970 79 -214 739 N ATOM 142 CA ARG A 166 -10.573 22.534 123.888 1.00 43.76 C ANISOU 142 CA ARG A 166 6698 5948 3981 159 -255 718 C ATOM 143 C ARG A 166 -9.827 21.699 124.934 1.00 46.40 C ANISOU 143 C ARG A 166 7149 6284 4196 303 -368 831 C ATOM 144 O ARG A 166 -10.225 20.564 125.233 1.00 47.95 O ANISOU 144 O ARG A 166 7481 6368 4367 301 -339 1015 O ATOM 145 CB ARG A 166 -11.897 23.034 124.453 1.00 43.60 C ANISOU 145 CB ARG A 166 6701 6034 3831 98 -115 785 C ATOM 146 CG ARG A 166 -12.532 24.094 123.562 1.00 43.18 C ANISOU 146 CG ARG A 166 6533 6009 3864 15 -36 656 C ATOM 147 CD ARG A 166 -13.716 24.729 124.247 1.00 42.85 C ANISOU 147 CD ARG A 166 6495 6123 3661 39 99 705 C ATOM 148 NE ARG A 166 -14.351 25.681 123.361 1.00 40.82 N ANISOU 148 NE ARG A 166 6138 5879 3490 -3 160 595 N ATOM 149 CZ ARG A 166 -15.014 26.755 123.748 1.00 38.69 C ANISOU 149 CZ ARG A 166 5876 5733 3091 93 233 531 C ATOM 150 NH1 ARG A 166 -15.181 27.018 125.037 1.00 39.92 N ANISOU 150 NH1 ARG A 166 6139 6026 3002 241 272 557 N ATOM 151 NH2 ARG A 166 -15.534 27.535 122.821 1.00 38.09 N ANISOU 151 NH2 ARG A 166 5722 5638 3112 67 268 443 N ATOM 152 N LYS A 167 -8.761 22.261 125.494 1.00 46.56 N ANISOU 152 N LYS A 167 7125 6422 4141 412 -517 735 N ATOM 153 CA LYS A 167 -7.833 21.490 126.340 1.00 50.36 C ANISOU 153 CA LYS A 167 7682 6922 4527 581 -670 826 C ATOM 154 C LYS A 167 -8.173 21.590 127.818 1.00 52.11 C ANISOU 154 C LYS A 167 8070 7258 4472 644 -696 925 C ATOM 155 O LYS A 167 -7.744 20.739 128.614 1.00 54.85 O ANISOU 155 O LYS A 167 8543 7594 4702 778 -792 1067 O ATOM 156 CB LYS A 167 -6.387 21.927 126.037 1.00 50.59 C ANISOU 156 CB LYS A 167 7524 7051 4646 660 -846 689 C ATOM 157 CG LYS A 167 -6.020 21.864 124.540 1.00 50.12 C ANISOU 157 CG LYS A 167 7294 6924 4825 623 -784 602 C ATOM 158 N SER A 168 -8.951 22.608 128.203 1.00 52.85 N ANISOU 158 N SER A 168 8187 7460 4434 580 -607 855 N ATOM 159 CA SER A 168 -9.289 22.839 129.641 1.00 55.91 C ANISOU 159 CA SER A 168 8753 7990 4498 679 -612 922 C ATOM 160 C SER A 168 -10.600 23.625 129.835 1.00 57.04 C ANISOU 160 C SER A 168 8930 8228 4512 638 -404 904 C ATOM 161 O SER A 168 -11.221 24.094 128.863 1.00 55.05 O ANISOU 161 O SER A 168 8553 7931 4431 526 -284 829 O ATOM 162 CB SER A 168 -8.159 23.591 130.322 1.00 55.85 C ANISOU 162 CB SER A 168 8765 8091 4361 775 -867 765 C ATOM 163 OG SER A 168 -8.083 24.891 129.750 1.00 54.52 O ANISOU 163 OG SER A 168 8502 7932 4281 677 -899 538 O ATOM 164 N GLY A 169 -11.036 23.672 131.095 1.00 59.13 N ANISOU 164 N GLY A 169 9368 8639 4457 756 -353 997 N ATOM 165 CA GLY A 169 -12.227 24.395 131.547 1.00 61.15 C ANISOU 165 CA GLY A 169 9673 9051 4509 807 -143 996 C ATOM 166 C GLY A 169 -13.571 23.710 131.411 1.00 63.54 C ANISOU 166 C GLY A 169 9897 9415 4830 717 140 1248 C ATOM 167 O GLY A 169 -13.660 22.533 131.161 1.00 64.78 O ANISOU 167 O GLY A 169 10029 9467 5116 595 168 1461 O ATOM 168 N LEU A 170 -14.621 24.503 131.583 1.00 69.65 N ANISOU 168 N LEU A 170 10633 10362 5467 784 337 1219 N ATOM 169 CA LEU A 170 -16.035 24.124 131.352 1.00 70.99 C ANISOU 169 CA LEU A 170 10638 10663 5671 687 621 1444 C ATOM 170 C LEU A 170 -16.354 23.242 130.163 1.00 68.14 C ANISOU 170 C LEU A 170 10093 10132 5663 417 640 1573 C ATOM 171 O LEU A 170 -17.202 22.330 130.263 1.00 67.13 O ANISOU 171 O LEU A 170 9891 10062 5552 265 793 1864 O ATOM 172 CB LEU A 170 -16.903 25.386 131.172 1.00 71.76 C ANISOU 172 CB LEU A 170 10646 10923 5693 818 770 1289 C ATOM 173 CG LEU A 170 -17.110 26.271 132.426 1.00 76.88 C ANISOU 173 CG LEU A 170 11494 11795 5918 1130 846 1197 C ATOM 174 CD1 LEU A 170 -18.457 26.998 132.302 1.00 79.19 C ANISOU 174 CD1 LEU A 170 11635 12324 6129 1268 1116 1209 C ATOM 175 CD2 LEU A 170 -17.014 25.554 133.775 1.00 77.54 C ANISOU 175 CD2 LEU A 170 11759 12036 5667 1229 899 1409 C ATOM 176 N SER A 171 -15.755 23.534 129.015 1.00 59.40 N ANISOU 176 N SER A 171 8914 8826 4827 339 492 1368 N ATOM 177 CA SER A 171 -16.004 22.680 127.885 1.00 55.52 C ANISOU 177 CA SER A 171 8303 8157 4633 109 487 1462 C ATOM 178 C SER A 171 -14.727 21.971 127.436 1.00 53.82 C ANISOU 178 C SER A 171 8186 7686 4576 87 273 1399 C ATOM 179 O SER A 171 -14.580 21.722 126.248 1.00 53.04 O ANISOU 179 O SER A 171 8013 7416 4722 -28 218 1327 O ATOM 180 CB SER A 171 -16.755 23.421 126.717 1.00 56.14 C ANISOU 180 CB SER A 171 8180 8253 4897 26 558 1343 C ATOM 181 N ALA A 172 -13.825 21.598 128.360 1.00 53.20 N ANISOU 181 N ALA A 172 8272 7596 4343 220 153 1434 N ATOM 182 CA ALA A 172 -12.696 20.719 128.013 1.00 51.76 C ANISOU 182 CA ALA A 172 8167 7200 4298 242 -31 1429 C ATOM 183 C ALA A 172 -13.215 19.518 127.222 1.00 52.12 C ANISOU 183 C ALA A 172 8234 7026 4541 60 7 1596 C ATOM 184 O ALA A 172 -14.178 18.892 127.613 1.00 51.86 O ANISOU 184 O ALA A 172 8246 7006 4451 -72 126 1839 O ATOM 185 CB ALA A 172 -11.948 20.236 129.241 1.00 55.28 C ANISOU 185 CB ALA A 172 8795 7682 4525 407 -148 1535 C ATOM 186 N GLY A 173 -12.601 19.224 126.079 1.00 49.00 N ANISOU 186 N GLY A 173 7811 6434 4370 44 -94 1466 N ATOM 187 CA GLY A 173 -12.967 18.035 125.305 1.00 50.75 C ANISOU 187 CA GLY A 173 8130 6390 4761 -104 -108 1586 C ATOM 188 C GLY A 173 -13.934 18.298 124.156 1.00 48.07 C ANISOU 188 C GLY A 173 7654 6021 4589 -317 -26 1531 C ATOM 189 O GLY A 173 -13.948 17.550 123.182 1.00 49.35 O ANISOU 189 O GLY A 173 7896 5942 4913 -410 -93 1516 O ATOM 190 N LYS A 174 -14.737 19.334 124.268 1.00 47.23 N ANISOU 190 N LYS A 174 7366 6152 4427 -368 103 1497 N ATOM 191 CA LYS A 174 -15.510 19.842 123.117 1.00 47.77 C ANISOU 191 CA LYS A 174 7270 6235 4646 -513 154 1403 C ATOM 192 C LYS A 174 -14.586 20.476 122.064 1.00 46.08 C ANISOU 192 C LYS A 174 7012 5947 4546 -412 67 1133 C ATOM 193 O LYS A 174 -13.406 20.757 122.347 1.00 44.55 O ANISOU 193 O LYS A 174 6853 5764 4309 -237 -11 1017 O ATOM 194 CB LYS A 174 -16.589 20.813 123.628 1.00 47.72 C ANISOU 194 CB LYS A 174 7084 6523 4522 -525 321 1450 C ATOM 195 CG LYS A 174 -17.612 20.096 124.564 1.00 51.16 C ANISOU 195 CG LYS A 174 7512 7080 4845 -655 448 1768 C ATOM 196 N SER A 175 -15.096 20.711 120.865 1.00 44.15 N ANISOU 196 N SER A 175 6681 5655 4438 -530 76 1049 N ATOM 197 CA SER A 175 -14.280 21.328 119.834 1.00 44.01 C ANISOU 197 CA SER A 175 6622 5591 4505 -448 21 826 C ATOM 198 C SER A 175 -14.875 22.600 119.258 1.00 40.97 C ANISOU 198 C SER A 175 6082 5345 4138 -481 86 718 C ATOM 199 O SER A 175 -16.060 22.879 119.385 1.00 41.43 O ANISOU 199 O SER A 175 6044 5519 4175 -568 166 806 O ATOM 200 CB SER A 175 -14.047 20.342 118.678 1.00 47.16 C ANISOU 200 CB SER A 175 7138 5745 5033 -501 -60 790 C ATOM 201 OG SER A 175 -15.298 19.887 118.268 1.00 48.14 O ANISOU 201 OG SER A 175 7262 5811 5216 -721 -51 900 O ATOM 202 N ASP A 176 -14.027 23.359 118.587 1.00 37.32 N ANISOU 202 N ASP A 176 5587 4877 3714 -404 50 543 N ATOM 203 CA ASP A 176 -14.446 24.540 117.887 1.00 35.43 C ANISOU 203 CA ASP A 176 5252 4711 3498 -427 86 441 C ATOM 204 C ASP A 176 -14.003 24.314 116.416 1.00 34.33 C ANISOU 204 C ASP A 176 5129 4445 3469 -465 45 346 C ATOM 205 O ASP A 176 -12.909 23.777 116.146 1.00 33.26 O ANISOU 205 O ASP A 176 5044 4231 3359 -392 0 298 O ATOM 206 CB ASP A 176 -13.740 25.782 118.395 1.00 34.89 C ANISOU 206 CB ASP A 176 5166 4734 3356 -324 70 328 C ATOM 207 CG ASP A 176 -14.129 26.138 119.827 1.00 37.82 C ANISOU 207 CG ASP A 176 5569 5233 3567 -240 105 381 C ATOM 208 OD1 ASP A 176 -15.083 26.941 119.999 1.00 39.43 O ANISOU 208 OD1 ASP A 176 5741 5534 3705 -208 180 378 O ATOM 209 OD2 ASP A 176 -13.515 25.591 120.765 1.00 38.46 O ANISOU 209 OD2 ASP A 176 5715 5327 3571 -179 61 431 O ATOM 210 N VAL A 177 -14.808 24.826 115.518 1.00 33.92 N ANISOU 210 N VAL A 177 5027 4407 3454 -542 64 318 N ATOM 211 CA VAL A 177 -14.508 24.705 114.056 1.00 34.81 C ANISOU 211 CA VAL A 177 5178 4419 3627 -570 32 228 C ATOM 212 C VAL A 177 -14.217 26.066 113.461 1.00 32.24 C ANISOU 212 C VAL A 177 4796 4162 3291 -540 57 133 C ATOM 213 O VAL A 177 -14.935 27.025 113.714 1.00 33.89 O ANISOU 213 O VAL A 177 4952 4451 3471 -541 80 141 O ATOM 214 CB VAL A 177 -15.631 23.921 113.336 1.00 37.17 C ANISOU 214 CB VAL A 177 5515 4635 3972 -710 -15 286 C ATOM 215 CG1 VAL A 177 -15.420 23.917 111.806 1.00 37.60 C ANISOU 215 CG1 VAL A 177 5644 4601 4040 -718 -57 175 C ATOM 216 CG2 VAL A 177 -15.610 22.472 113.798 1.00 39.81 C ANISOU 216 CG2 VAL A 177 5974 4824 4326 -760 -69 376 C ATOM 217 N TYR A 178 -13.133 26.140 112.671 1.00 33.66 N ANISOU 217 N TYR A 178 4994 4311 3483 -499 59 55 N ATOM 218 CA TYR A 178 -12.707 27.351 112.040 1.00 31.80 C ANISOU 218 CA TYR A 178 4720 4121 3238 -509 83 -2 C ATOM 219 C TYR A 178 -12.511 27.081 110.529 1.00 32.47 C ANISOU 219 C TYR A 178 4855 4162 3317 -514 103 -43 C ATOM 220 O TYR A 178 -12.105 25.963 110.150 1.00 32.01 O ANISOU 220 O TYR A 178 4861 4046 3256 -455 101 -64 O ATOM 221 CB TYR A 178 -11.408 27.897 112.583 1.00 33.46 C ANISOU 221 CB TYR A 178 4865 4398 3448 -479 79 -26 C ATOM 222 CG TYR A 178 -11.401 28.021 114.087 1.00 33.77 C ANISOU 222 CG TYR A 178 4896 4477 3456 -449 34 -5 C ATOM 223 CD1 TYR A 178 -12.360 28.799 114.725 1.00 34.83 C ANISOU 223 CD1 TYR A 178 5070 4622 3539 -452 31 0 C ATOM 224 CD2 TYR A 178 -10.450 27.369 114.865 1.00 35.24 C ANISOU 224 CD2 TYR A 178 5047 4702 3638 -382 -4 10 C ATOM 225 CE1 TYR A 178 -12.365 28.914 116.141 1.00 35.40 C ANISOU 225 CE1 TYR A 178 5170 4745 3533 -392 0 10 C ATOM 226 CE2 TYR A 178 -10.437 27.514 116.267 1.00 34.37 C ANISOU 226 CE2 TYR A 178 4959 4638 3462 -346 -61 29 C ATOM 227 CZ TYR A 178 -11.406 28.282 116.891 1.00 34.97 C ANISOU 227 CZ TYR A 178 5098 4722 3464 -354 -51 24 C ATOM 228 OH TYR A 178 -11.464 28.450 118.305 1.00 34.49 O ANISOU 228 OH TYR A 178 5096 4719 3287 -286 -94 34 O ATOM 229 N TYR A 179 -12.800 28.130 109.762 1.00 32.16 N ANISOU 229 N TYR A 179 4819 4142 3256 -559 117 -55 N ATOM 230 CA TYR A 179 -12.517 28.160 108.333 1.00 35.08 C ANISOU 230 CA TYR A 179 5246 4503 3579 -557 150 -85 C ATOM 231 C TYR A 179 -11.483 29.243 108.005 1.00 35.13 C ANISOU 231 C TYR A 179 5194 4582 3570 -585 214 -71 C ATOM 232 O TYR A 179 -11.379 30.303 108.670 1.00 34.78 O ANISOU 232 O TYR A 179 5114 4545 3555 -646 190 -48 O ATOM 233 CB TYR A 179 -13.847 28.364 107.586 1.00 35.20 C ANISOU 233 CB TYR A 179 5329 4478 3564 -604 92 -77 C ATOM 234 CG TYR A 179 -14.709 27.124 107.556 1.00 36.08 C ANISOU 234 CG TYR A 179 5495 4521 3691 -634 12 -77 C ATOM 235 CD1 TYR A 179 -15.578 26.846 108.613 1.00 34.45 C ANISOU 235 CD1 TYR A 179 5214 4330 3545 -683 -27 -12 C ATOM 236 CD2 TYR A 179 -14.719 26.245 106.444 1.00 37.95 C ANISOU 236 CD2 TYR A 179 5875 4676 3868 -626 -33 -135 C ATOM 237 CE1 TYR A 179 -16.367 25.741 108.648 1.00 34.67 C ANISOU 237 CE1 TYR A 179 5276 4294 3603 -769 -110 24 C ATOM 238 CE2 TYR A 179 -15.510 25.102 106.481 1.00 39.02 C ANISOU 238 CE2 TYR A 179 6091 4705 4030 -702 -149 -132 C ATOM 239 CZ TYR A 179 -16.349 24.857 107.575 1.00 36.65 C ANISOU 239 CZ TYR A 179 5685 4421 3819 -800 -191 -36 C ATOM 240 OH TYR A 179 -17.174 23.769 107.631 1.00 36.28 O ANISOU 240 OH TYR A 179 5699 4272 3812 -935 -313 6 O ATOM 241 N PHE A 180 -10.693 28.986 106.942 1.00 35.95 N ANISOU 241 N PHE A 180 5304 4739 3616 -545 295 -79 N ATOM 242 CA PHE A 180 -9.711 29.946 106.465 1.00 35.76 C ANISOU 242 CA PHE A 180 5199 4814 3572 -609 375 -23 C ATOM 243 C PHE A 180 -9.908 30.210 104.981 1.00 37.49 C ANISOU 243 C PHE A 180 5524 5044 3675 -608 439 -4 C ATOM 244 O PHE A 180 -9.967 29.241 104.248 1.00 36.33 O ANISOU 244 O PHE A 180 5461 4899 3443 -491 471 -61 O ATOM 245 CB PHE A 180 -8.327 29.365 106.682 1.00 37.95 C ANISOU 245 CB PHE A 180 5316 5235 3867 -534 452 -13 C ATOM 246 CG PHE A 180 -8.018 29.139 108.145 1.00 38.75 C ANISOU 246 CG PHE A 180 5318 5343 4062 -529 370 -20 C ATOM 247 CD1 PHE A 180 -7.508 30.154 108.893 1.00 39.84 C ANISOU 247 CD1 PHE A 180 5353 5525 4259 -667 314 23 C ATOM 248 CD2 PHE A 180 -8.347 27.944 108.759 1.00 40.08 C ANISOU 248 CD2 PHE A 180 5542 5444 4242 -403 323 -66 C ATOM 249 CE1 PHE A 180 -7.218 29.974 110.275 1.00 41.79 C ANISOU 249 CE1 PHE A 180 5534 5785 4558 -654 215 8 C ATOM 250 CE2 PHE A 180 -8.092 27.748 110.131 1.00 41.47 C ANISOU 250 CE2 PHE A 180 5651 5632 4473 -388 245 -56 C ATOM 251 CZ PHE A 180 -7.546 28.781 110.882 1.00 41.03 C ANISOU 251 CZ PHE A 180 5482 5649 4456 -504 190 -26 C ATOM 252 N SER A 181 -9.996 31.480 104.583 1.00 36.86 N ANISOU 252 N SER A 181 5478 4950 3577 -728 442 70 N ATOM 253 CA SER A 181 -10.024 31.866 103.168 1.00 39.22 C ANISOU 253 CA SER A 181 5882 5279 3740 -734 514 123 C ATOM 254 C SER A 181 -8.706 31.459 102.486 1.00 40.53 C ANISOU 254 C SER A 181 5939 5636 3824 -681 690 165 C ATOM 255 O SER A 181 -7.684 31.179 103.123 1.00 39.41 O ANISOU 255 O SER A 181 5601 5615 3757 -673 746 180 O ATOM 256 CB SER A 181 -10.168 33.401 103.003 1.00 38.49 C ANISOU 256 CB SER A 181 5856 5114 3652 -887 483 232 C ATOM 257 OG SER A 181 -8.975 34.109 103.394 1.00 41.30 O ANISOU 257 OG SER A 181 6076 5538 4075 -1042 537 328 O ATOM 258 N PRO A 182 -8.681 31.557 101.177 1.00 42.61 N ANISOU 258 N PRO A 182 6312 5960 3918 -641 783 204 N ATOM 259 CA PRO A 182 -7.399 31.301 100.493 1.00 45.28 C ANISOU 259 CA PRO A 182 6520 6534 4148 -570 994 271 C ATOM 260 C PRO A 182 -6.225 32.163 100.954 1.00 47.95 C ANISOU 260 C PRO A 182 6596 7029 4593 -756 1079 430 C ATOM 261 O PRO A 182 -5.090 31.663 101.009 1.00 50.20 O ANISOU 261 O PRO A 182 6650 7547 4877 -673 1217 464 O ATOM 262 CB PRO A 182 -7.729 31.578 99.030 1.00 46.57 C ANISOU 262 CB PRO A 182 6883 6724 4084 -532 1069 317 C ATOM 263 CG PRO A 182 -9.169 31.201 98.917 1.00 44.73 C ANISOU 263 CG PRO A 182 6889 6278 3826 -477 874 188 C ATOM 264 CD PRO A 182 -9.820 31.591 100.248 1.00 42.17 C ANISOU 264 CD PRO A 182 6495 5797 3730 -599 705 170 C ATOM 265 N SER A 183 -6.481 33.426 101.306 1.00 47.89 N ANISOU 265 N SER A 183 6623 6894 4677 -999 980 528 N ATOM 266 CA SER A 183 -5.423 34.301 101.847 1.00 51.07 C ANISOU 266 CA SER A 183 6807 7394 5202 -1244 996 676 C ATOM 267 C SER A 183 -5.086 34.012 103.298 1.00 49.78 C ANISOU 267 C SER A 183 6477 7218 5216 -1264 869 597 C ATOM 268 O SER A 183 -4.100 34.546 103.807 1.00 50.66 O ANISOU 268 O SER A 183 6373 7444 5431 -1459 855 702 O ATOM 269 CB SER A 183 -5.812 35.767 101.753 1.00 53.09 C ANISOU 269 CB SER A 183 7234 7451 5486 -1499 895 795 C ATOM 270 OG SER A 183 -6.103 36.089 100.389 1.00 59.75 O ANISOU 270 OG SER A 183 8247 8309 6145 -1483 1005 897 O ATOM 271 N GLY A 184 -5.905 33.221 103.979 1.00 45.94 N ANISOU 271 N GLY A 184 6092 6599 4762 -1091 762 430 N ATOM 272 CA GLY A 184 -5.623 32.910 105.382 1.00 45.31 C ANISOU 272 CA GLY A 184 5886 6512 4817 -1089 643 364 C ATOM 273 C GLY A 184 -6.457 33.632 106.411 1.00 45.54 C ANISOU 273 C GLY A 184 6068 6310 4923 -1186 454 307 C ATOM 274 O GLY A 184 -6.176 33.494 107.627 1.00 43.15 O ANISOU 274 O GLY A 184 5683 6008 4702 -1196 347 259 O ATOM 275 N LYS A 185 -7.505 34.345 105.984 1.00 44.00 N ANISOU 275 N LYS A 185 6104 5932 4681 -1215 408 304 N ATOM 276 CA LYS A 185 -8.436 35.009 106.936 1.00 42.25 C ANISOU 276 CA LYS A 185 6049 5503 4501 -1227 248 236 C ATOM 277 C LYS A 185 -9.234 33.941 107.667 1.00 40.21 C ANISOU 277 C LYS A 185 5790 5239 4249 -1037 216 121 C ATOM 278 O LYS A 185 -9.722 32.985 107.024 1.00 39.26 O ANISOU 278 O LYS A 185 5680 5155 4078 -911 278 91 O ATOM 279 CB LYS A 185 -9.394 35.976 106.229 1.00 42.73 C ANISOU 279 CB LYS A 185 6343 5391 4499 -1243 213 271 C ATOM 280 CG LYS A 185 -8.727 37.101 105.430 1.00 46.86 C ANISOU 280 CG LYS A 185 6929 5874 5002 -1453 238 420 C ATOM 281 CD LYS A 185 -9.758 37.875 104.616 1.00 46.83 C ANISOU 281 CD LYS A 185 7181 5699 4910 -1406 203 461 C ATOM 282 CE LYS A 185 -9.098 38.974 103.779 1.00 50.43 C ANISOU 282 CE LYS A 185 7736 6092 5331 -1632 232 644 C ATOM 283 NZ LYS A 185 -10.109 39.789 103.078 1.00 50.38 N ANISOU 283 NZ LYS A 185 8016 5890 5234 -1561 168 692 N ATOM 284 N LYS A 186 -9.426 34.098 108.991 1.00 37.27 N ANISOU 284 N LYS A 186 5433 4808 3920 -1024 111 62 N ATOM 285 CA LYS A 186 -10.059 33.099 109.825 1.00 35.76 C ANISOU 285 CA LYS A 186 5223 4634 3730 -875 93 -5 C ATOM 286 C LYS A 186 -11.529 33.417 110.084 1.00 35.19 C ANISOU 286 C LYS A 186 5286 4463 3621 -785 52 -37 C ATOM 287 O LYS A 186 -11.854 34.588 110.359 1.00 38.61 O ANISOU 287 O LYS A 186 5846 4790 4034 -802 -11 -47 O ATOM 288 CB LYS A 186 -9.299 33.029 111.154 1.00 38.53 C ANISOU 288 CB LYS A 186 5494 5030 4115 -896 15 -31 C ATOM 289 CG LYS A 186 -9.768 31.961 112.123 1.00 38.11 C ANISOU 289 CG LYS A 186 5424 5006 4047 -755 3 -68 C ATOM 290 CD LYS A 186 -8.907 32.041 113.408 1.00 40.37 C ANISOU 290 CD LYS A 186 5654 5345 4338 -776 -97 -88 C ATOM 291 CE LYS A 186 -9.526 31.249 114.564 1.00 39.87 C ANISOU 291 CE LYS A 186 5633 5292 4222 -640 -118 -105 C ATOM 292 NZ LYS A 186 -8.526 30.935 115.589 1.00 40.26 N ANISOU 292 NZ LYS A 186 5606 5427 4263 -627 -211 -107 N ATOM 293 N PHE A 187 -12.427 32.428 109.972 1.00 32.60 N ANISOU 293 N PHE A 187 4936 4168 3281 -688 80 -45 N ATOM 294 CA PHE A 187 -13.852 32.640 110.229 1.00 33.09 C ANISOU 294 CA PHE A 187 5048 4208 3316 -601 53 -46 C ATOM 295 C PHE A 187 -14.307 31.644 111.328 1.00 34.53 C ANISOU 295 C PHE A 187 5154 4457 3505 -541 60 -42 C ATOM 296 O PHE A 187 -13.903 30.494 111.347 1.00 35.59 O ANISOU 296 O PHE A 187 5237 4617 3668 -560 78 -32 O ATOM 297 CB PHE A 187 -14.717 32.473 108.971 1.00 34.72 C ANISOU 297 CB PHE A 187 5277 4414 3501 -591 55 -18 C ATOM 298 CG PHE A 187 -14.309 33.407 107.883 1.00 34.03 C ANISOU 298 CG PHE A 187 5285 4265 3376 -643 58 5 C ATOM 299 CD1 PHE A 187 -13.179 33.167 107.155 1.00 36.59 C ANISOU 299 CD1 PHE A 187 5594 4616 3691 -724 119 21 C ATOM 300 CD2 PHE A 187 -14.957 34.599 107.715 1.00 36.61 C ANISOU 300 CD2 PHE A 187 5725 4514 3670 -596 9 26 C ATOM 301 CE1 PHE A 187 -12.739 34.095 106.206 1.00 37.94 C ANISOU 301 CE1 PHE A 187 5850 4748 3814 -798 142 81 C ATOM 302 CE2 PHE A 187 -14.529 35.527 106.806 1.00 39.82 C ANISOU 302 CE2 PHE A 187 6255 4836 4038 -662 5 76 C ATOM 303 CZ PHE A 187 -13.410 35.262 106.032 1.00 38.12 C ANISOU 303 CZ PHE A 187 6012 4661 3809 -785 78 115 C ATOM 304 N ARG A 188 -15.201 32.088 112.185 1.00 34.80 N ANISOU 304 N ARG A 188 5200 4521 3499 -449 54 -38 N ATOM 305 CA ARG A 188 -15.597 31.310 113.385 1.00 33.93 C ANISOU 305 CA ARG A 188 5027 4498 3365 -396 82 -5 C ATOM 306 C ARG A 188 -17.076 31.007 113.441 1.00 34.25 C ANISOU 306 C ARG A 188 4976 4643 3393 -344 118 71 C ATOM 307 O ARG A 188 -17.516 30.362 114.405 1.00 34.37 O ANISOU 307 O ARG A 188 4923 4755 3378 -319 163 137 O ATOM 308 CB ARG A 188 -15.207 32.063 114.706 1.00 34.14 C ANISOU 308 CB ARG A 188 5135 4525 3308 -311 60 -58 C ATOM 309 CG ARG A 188 -13.751 32.488 114.775 1.00 35.80 C ANISOU 309 CG ARG A 188 5402 4658 3540 -400 -13 -120 C ATOM 310 CD ARG A 188 -13.356 32.771 116.236 1.00 37.11 C ANISOU 310 CD ARG A 188 5644 4842 3612 -336 -71 -169 C ATOM 311 NE ARG A 188 -12.099 33.500 116.329 1.00 38.02 N ANISOU 311 NE ARG A 188 5817 4880 3746 -449 -189 -230 N ATOM 312 CZ ARG A 188 -11.485 33.741 117.503 1.00 40.47 C ANISOU 312 CZ ARG A 188 6199 5196 3978 -437 -295 -286 C ATOM 313 NH1 ARG A 188 -12.017 33.306 118.635 1.00 38.41 N ANISOU 313 NH1 ARG A 188 5982 5016 3594 -289 -271 -286 N ATOM 314 NH2 ARG A 188 -10.323 34.371 117.520 1.00 42.50 N ANISOU 314 NH2 ARG A 188 6474 5399 4275 -591 -432 -324 N ATOM 315 N SER A 189 -17.880 31.432 112.445 1.00 32.31 N ANISOU 315 N SER A 189 4706 4405 3162 -333 98 87 N ATOM 316 CA SER A 189 -19.287 31.011 112.451 1.00 33.27 C ANISOU 316 CA SER A 189 4672 4675 3291 -314 114 185 C ATOM 317 C SER A 189 -19.880 31.026 111.018 1.00 35.47 C ANISOU 317 C SER A 189 4921 4944 3610 -374 36 202 C ATOM 318 O SER A 189 -19.283 31.662 110.083 1.00 32.93 O ANISOU 318 O SER A 189 4732 4503 3276 -376 -2 138 O ATOM 319 CB SER A 189 -20.122 31.955 113.307 1.00 34.74 C ANISOU 319 CB SER A 189 4819 4989 3391 -104 174 200 C ATOM 320 OG SER A 189 -20.225 33.243 112.637 1.00 35.82 O ANISOU 320 OG SER A 189 5070 5042 3497 18 128 136 O ATOM 321 N LYS A 190 -21.023 30.350 110.893 1.00 36.46 N ANISOU 321 N LYS A 190 4873 5206 3771 -435 9 305 N ATOM 322 CA LYS A 190 -21.710 30.268 109.619 1.00 40.27 C ANISOU 322 CA LYS A 190 5313 5707 4279 -503 -102 327 C ATOM 323 C LYS A 190 -22.136 31.655 109.116 1.00 40.02 C ANISOU 323 C LYS A 190 5309 5703 4191 -314 -123 307 C ATOM 324 O LYS A 190 -21.849 31.976 107.969 1.00 39.04 O ANISOU 324 O LYS A 190 5314 5474 4043 -337 -200 263 O ATOM 325 CB LYS A 190 -22.870 29.302 109.674 1.00 42.90 C ANISOU 325 CB LYS A 190 5427 6196 4674 -646 -160 458 C ATOM 326 CG LYS A 190 -23.473 29.028 108.310 1.00 44.91 C ANISOU 326 CG LYS A 190 5665 6446 4951 -764 -332 466 C ATOM 327 CD LYS A 190 -24.530 27.901 108.393 1.00 47.76 C ANISOU 327 CD LYS A 190 5814 6936 5397 -996 -431 606 C ATOM 328 CE LYS A 190 -24.962 27.516 107.006 1.00 50.45 C ANISOU 328 CE LYS A 190 6200 7225 5743 -1145 -652 581 C ATOM 329 NZ LYS A 190 -26.060 26.514 107.020 1.00 52.41 N ANISOU 329 NZ LYS A 190 6232 7595 6085 -1418 -799 728 N ATOM 330 N PRO A 191 -22.813 32.458 109.943 1.00 39.99 N ANISOU 330 N PRO A 191 5214 5835 4146 -106 -54 342 N ATOM 331 CA PRO A 191 -23.198 33.804 109.467 1.00 42.56 C ANISOU 331 CA PRO A 191 5620 6140 4408 116 -90 318 C ATOM 332 C PRO A 191 -22.010 34.710 109.118 1.00 40.80 C ANISOU 332 C PRO A 191 5705 5652 4143 133 -103 212 C ATOM 333 O PRO A 191 -22.108 35.531 108.191 1.00 42.00 O ANISOU 333 O PRO A 191 5984 5714 4259 203 -177 211 O ATOM 334 CB PRO A 191 -23.979 34.416 110.645 1.00 45.21 C ANISOU 334 CB PRO A 191 5843 6652 4679 385 14 350 C ATOM 335 CG PRO A 191 -24.072 33.368 111.692 1.00 44.94 C ANISOU 335 CG PRO A 191 5637 6768 4668 276 114 417 C ATOM 336 CD PRO A 191 -23.303 32.159 111.307 1.00 42.72 C ANISOU 336 CD PRO A 191 5396 6361 4474 -35 62 413 C ATOM 337 N GLN A 192 -20.887 34.559 109.802 1.00 38.59 N ANISOU 337 N GLN A 192 5538 5255 3868 49 -45 144 N ATOM 338 CA GLN A 192 -19.693 35.323 109.439 1.00 40.29 C ANISOU 338 CA GLN A 192 5992 5249 4065 -6 -68 75 C ATOM 339 C GLN A 192 -19.154 34.863 108.071 1.00 38.13 C ANISOU 339 C GLN A 192 5755 4917 3813 -182 -107 92 C ATOM 340 O GLN A 192 -18.793 35.706 107.200 1.00 39.39 O ANISOU 340 O GLN A 192 6079 4954 3932 -190 -143 101 O ATOM 341 CB GLN A 192 -18.615 35.154 110.491 1.00 41.85 C ANISOU 341 CB GLN A 192 6245 5386 4270 -76 -22 13 C ATOM 342 CG GLN A 192 -17.342 35.929 110.290 1.00 43.68 C ANISOU 342 CG GLN A 192 6668 5426 4500 -179 -57 -35 C ATOM 343 CD GLN A 192 -16.316 35.662 111.409 1.00 48.04 C ANISOU 343 CD GLN A 192 7225 5964 5063 -253 -46 -90 C ATOM 344 OE1 GLN A 192 -16.430 34.668 112.166 1.00 42.09 O ANISOU 344 OE1 GLN A 192 6339 5335 4317 -243 0 -83 O ATOM 345 NE2 GLN A 192 -15.321 36.572 111.536 1.00 47.10 N ANISOU 345 NE2 GLN A 192 7267 5689 4940 -342 -108 -130 N ATOM 346 N LEU A 193 -19.093 33.543 107.882 1.00 35.50 N ANISOU 346 N LEU A 193 5304 4659 3524 -312 -99 102 N ATOM 347 CA LEU A 193 -18.653 33.022 106.600 1.00 38.23 C ANISOU 347 CA LEU A 193 5714 4960 3850 -429 -132 96 C ATOM 348 C LEU A 193 -19.634 33.423 105.450 1.00 38.03 C ANISOU 348 C LEU A 193 5711 4968 3767 -377 -234 141 C ATOM 349 O LEU A 193 -19.181 33.768 104.340 1.00 37.65 O ANISOU 349 O LEU A 193 5810 4848 3644 -405 -253 144 O ATOM 350 CB LEU A 193 -18.529 31.530 106.707 1.00 38.48 C ANISOU 350 CB LEU A 193 5669 5026 3925 -539 -132 81 C ATOM 351 CG LEU A 193 -18.040 30.698 105.555 1.00 40.75 C ANISOU 351 CG LEU A 193 6052 5260 4169 -623 -162 42 C ATOM 352 CD1 LEU A 193 -16.595 31.019 105.236 1.00 41.17 C ANISOU 352 CD1 LEU A 193 6206 5254 4182 -624 -63 6 C ATOM 353 CD2 LEU A 193 -18.190 29.214 105.948 1.00 42.10 C ANISOU 353 CD2 LEU A 193 6178 5422 4394 -708 -195 31 C ATOM 354 N ALA A 194 -20.948 33.370 105.719 1.00 37.85 N ANISOU 354 N ALA A 194 5528 5083 3768 -298 -297 194 N ATOM 355 CA ALA A 194 -21.954 33.686 104.671 1.00 41.48 C ANISOU 355 CA ALA A 194 5967 5615 4178 -238 -428 247 C ATOM 356 C ALA A 194 -21.931 35.164 104.284 1.00 42.66 C ANISOU 356 C ALA A 194 6287 5670 4252 -64 -441 268 C ATOM 357 O ALA A 194 -22.045 35.483 103.093 1.00 41.85 O ANISOU 357 O ALA A 194 6304 5532 4065 -57 -531 298 O ATOM 358 CB ALA A 194 -23.351 33.259 105.071 1.00 43.03 C ANISOU 358 CB ALA A 194 5886 6032 4431 -205 -497 325 C ATOM 359 N ARG A 195 -21.662 36.037 105.271 1.00 42.60 N ANISOU 359 N ARG A 195 6343 5587 4255 62 -361 247 N ATOM 360 CA ARG A 195 -21.529 37.478 105.055 1.00 45.01 C ANISOU 360 CA ARG A 195 6880 5725 4493 214 -385 260 C ATOM 361 C ARG A 195 -20.325 37.755 104.174 1.00 45.88 C ANISOU 361 C ARG A 195 7216 5655 4559 41 -371 267 C ATOM 362 O ARG A 195 -20.398 38.626 103.267 1.00 45.58 O ANISOU 362 O ARG A 195 7369 5507 4438 96 -435 332 O ATOM 363 CB ARG A 195 -21.394 38.287 106.340 1.00 46.57 C ANISOU 363 CB ARG A 195 7162 5834 4696 367 -327 207 C ATOM 364 CG ARG A 195 -22.692 38.316 107.169 1.00 51.75 C ANISOU 364 CG ARG A 195 7616 6698 5347 630 -312 222 C ATOM 365 N TYR A 196 -19.239 37.016 104.403 1.00 41.44 N ANISOU 365 N TYR A 196 6623 5082 4040 -153 -282 222 N ATOM 366 CA TYR A 196 -18.013 37.255 103.625 1.00 40.27 C ANISOU 366 CA TYR A 196 6629 4825 3847 -315 -231 251 C ATOM 367 C TYR A 196 -18.204 36.830 102.144 1.00 39.67 C ANISOU 367 C TYR A 196 6598 4811 3662 -348 -267 297 C ATOM 368 O TYR A 196 -17.859 37.576 101.217 1.00 40.17 O ANISOU 368 O TYR A 196 6846 4789 3626 -372 -268 379 O ATOM 369 CB TYR A 196 -16.842 36.523 104.258 1.00 38.39 C ANISOU 369 CB TYR A 196 6298 4611 3676 -466 -129 198 C ATOM 370 CG TYR A 196 -15.556 36.868 103.617 1.00 39.08 C ANISOU 370 CG TYR A 196 6479 4641 3727 -621 -55 251 C ATOM 371 CD1 TYR A 196 -14.926 38.081 103.908 1.00 40.71 C ANISOU 371 CD1 TYR A 196 6826 4690 3949 -701 -65 303 C ATOM 372 CD2 TYR A 196 -14.942 35.991 102.708 1.00 39.56 C ANISOU 372 CD2 TYR A 196 6496 4808 3726 -692 25 259 C ATOM 373 CE1 TYR A 196 -13.726 38.448 103.292 1.00 42.61 C ANISOU 373 CE1 TYR A 196 7114 4909 4164 -892 8 397 C ATOM 374 CE2 TYR A 196 -13.731 36.340 102.093 1.00 40.80 C ANISOU 374 CE2 TYR A 196 6695 4972 3833 -822 130 339 C ATOM 375 CZ TYR A 196 -13.147 37.567 102.385 1.00 43.27 C ANISOU 375 CZ TYR A 196 7098 5159 4182 -942 124 425 C ATOM 376 OH TYR A 196 -11.953 37.882 101.851 1.00 46.08 O ANISOU 376 OH TYR A 196 7442 5558 4507 -1114 231 536 O ATOM 377 N LEU A 197 -18.709 35.629 101.949 1.00 37.52 N ANISOU 377 N LEU A 197 6187 4672 3396 -363 -303 250 N ATOM 378 CA LEU A 197 -18.890 35.041 100.588 1.00 38.85 C ANISOU 378 CA LEU A 197 6428 4895 3437 -395 -366 256 C ATOM 379 C LEU A 197 -20.035 35.664 99.767 1.00 40.12 C ANISOU 379 C LEU A 197 6652 5084 3506 -275 -526 325 C ATOM 380 O LEU A 197 -20.018 35.657 98.505 1.00 40.97 O ANISOU 380 O LEU A 197 6913 5199 3454 -281 -582 356 O ATOM 381 CB LEU A 197 -19.089 33.507 100.704 1.00 36.84 C ANISOU 381 CB LEU A 197 6051 4723 3222 -470 -400 168 C ATOM 382 CG LEU A 197 -17.793 32.823 101.087 1.00 36.93 C ANISOU 382 CG LEU A 197 6062 4704 3264 -548 -251 108 C ATOM 383 CD1 LEU A 197 -18.021 31.404 101.581 1.00 39.45 C ANISOU 383 CD1 LEU A 197 6284 5046 3657 -601 -291 31 C ATOM 384 CD2 LEU A 197 -16.703 32.905 100.045 1.00 41.12 C ANISOU 384 CD2 LEU A 197 6747 5225 3649 -566 -145 117 C ATOM 385 N GLY A 198 -21.077 36.108 100.452 1.00 39.17 N ANISOU 385 N GLY A 198 6403 5012 3466 -141 -605 350 N ATOM 386 CA GLY A 198 -22.181 36.733 99.797 1.00 42.95 C ANISOU 386 CA GLY A 198 6900 5546 3872 16 -763 426 C ATOM 387 C GLY A 198 -22.816 35.799 98.794 1.00 43.50 C ANISOU 387 C GLY A 198 6916 5749 3863 -53 -923 415 C ATOM 388 O GLY A 198 -22.949 34.569 99.038 1.00 42.63 O ANISOU 388 O GLY A 198 6657 5721 3819 -195 -949 346 O ATOM 389 N ASN A 199 -23.203 36.335 97.641 1.00 44.49 N ANISOU 389 N ASN A 199 7195 5875 3831 31 -1056 483 N ATOM 390 CA ASN A 199 -23.911 35.510 96.680 1.00 45.34 C ANISOU 390 CA ASN A 199 7270 6112 3843 -29 -1261 464 C ATOM 391 C ASN A 199 -23.001 34.608 95.848 1.00 46.40 C ANISOU 391 C ASN A 199 7607 6184 3837 -188 -1220 374 C ATOM 392 O ASN A 199 -23.463 34.094 94.847 1.00 46.98 O ANISOU 392 O ASN A 199 7766 6318 3765 -218 -1408 347 O ATOM 393 CB ASN A 199 -24.794 36.388 95.766 1.00 47.72 C ANISOU 393 CB ASN A 199 7651 6470 4008 154 -1459 573 C ATOM 394 CG ASN A 199 -23.990 37.321 94.852 1.00 48.63 C ANISOU 394 CG ASN A 199 8130 6421 3925 213 -1388 648 C ATOM 395 OD1 ASN A 199 -22.764 37.273 94.762 1.00 46.87 O ANISOU 395 OD1 ASN A 199 8078 6076 3654 96 -1191 625 O ATOM 396 ND2 ASN A 199 -24.708 38.165 94.150 1.00 51.62 N ANISOU 396 ND2 ASN A 199 8611 6818 4183 397 -1553 761 N ATOM 397 N THR A 200 -21.711 34.486 96.176 1.00 44.81 N ANISOU 397 N THR A 200 7500 5875 3649 -259 -989 330 N ATOM 398 CA THR A 200 -20.820 33.648 95.375 1.00 46.83 C ANISOU 398 CA THR A 200 7941 6103 3746 -341 -921 244 C ATOM 399 C THR A 200 -21.023 32.169 95.738 1.00 48.21 C ANISOU 399 C THR A 200 8014 6294 4006 -456 -998 110 C ATOM 400 O THR A 200 -20.577 31.314 95.021 1.00 48.99 O ANISOU 400 O THR A 200 8290 6362 3958 -487 -1010 10 O ATOM 401 CB THR A 200 -19.319 34.027 95.505 1.00 45.39 C ANISOU 401 CB THR A 200 7857 5850 3538 -364 -642 269 C ATOM 402 OG1 THR A 200 -18.831 33.837 96.865 1.00 42.74 O ANISOU 402 OG1 THR A 200 7331 5482 3425 -421 -512 232 O ATOM 403 CG2 THR A 200 -19.120 35.466 95.069 1.00 46.01 C ANISOU 403 CG2 THR A 200 8081 5872 3526 -305 -591 427 C ATOM 404 N VAL A 201 -21.691 31.877 96.849 1.00 49.47 N ANISOU 404 N VAL A 201 7917 6494 4386 -510 -1046 114 N ATOM 405 CA VAL A 201 -21.990 30.496 97.257 1.00 50.79 C ANISOU 405 CA VAL A 201 7994 6651 4650 -657 -1141 26 C ATOM 406 C VAL A 201 -23.348 30.533 97.952 1.00 52.83 C ANISOU 406 C VAL A 201 7949 7047 5077 -703 -1293 112 C ATOM 407 O VAL A 201 -23.641 31.520 98.630 1.00 56.23 O ANISOU 407 O VAL A 201 8220 7552 5592 -580 -1210 204 O ATOM 408 CB VAL A 201 -20.972 29.966 98.315 1.00 50.64 C ANISOU 408 CB VAL A 201 7932 6550 4758 -694 -927 -24 C ATOM 409 CG1 VAL A 201 -19.512 30.067 97.870 1.00 50.34 C ANISOU 409 CG1 VAL A 201 8093 6441 4591 -623 -720 -74 C ATOM 410 CG2 VAL A 201 -21.136 30.712 99.594 1.00 51.69 C ANISOU 410 CG2 VAL A 201 7838 6735 5066 -652 -815 60 C ATOM 411 N ASP A 202 -24.118 29.444 97.892 1.00 52.07 N ANISOU 411 N ASP A 202 7768 6983 5034 -879 -1500 87 N ATOM 412 CA ASP A 202 -25.342 29.281 98.689 1.00 52.50 C ANISOU 412 CA ASP A 202 7465 7213 5270 -971 -1611 198 C ATOM 413 C ASP A 202 -25.044 28.325 99.857 1.00 51.02 C ANISOU 413 C ASP A 202 7177 6962 5245 -1121 -1498 190 C ATOM 414 O ASP A 202 -24.802 27.142 99.654 1.00 50.56 O ANISOU 414 O ASP A 202 7271 6757 5181 -1300 -1593 109 O ATOM 415 CB ASP A 202 -26.476 28.719 97.820 1.00 56.31 C ANISOU 415 CB ASP A 202 7888 7793 5713 -1129 -1955 217 C ATOM 416 CG ASP A 202 -27.835 28.732 98.529 1.00 59.41 C ANISOU 416 CG ASP A 202 7831 8453 6286 -1211 -2068 380 C ATOM 417 OD1 ASP A 202 -27.874 28.781 99.765 1.00 58.17 O ANISOU 417 OD1 ASP A 202 7444 8374 6283 -1195 -1877 458 O ATOM 418 OD2 ASP A 202 -28.881 28.681 97.854 1.00 65.18 O ANISOU 418 OD2 ASP A 202 8420 9349 6996 -1287 -2351 442 O ATOM 419 N LEU A 203 -25.034 28.844 101.065 1.00 50.10 N ANISOU 419 N LEU A 203 6853 6934 5249 -1029 -1306 269 N ATOM 420 CA LEU A 203 -24.688 28.059 102.235 1.00 49.00 C ANISOU 420 CA LEU A 203 6638 6744 5236 -1138 -1180 281 C ATOM 421 C LEU A 203 -25.900 27.569 103.017 1.00 51.33 C ANISOU 421 C LEU A 203 6588 7238 5675 -1293 -1256 432 C ATOM 422 O LEU A 203 -25.711 27.029 104.089 1.00 49.03 O ANISOU 422 O LEU A 203 6216 6935 5476 -1368 -1135 479 O ATOM 423 CB LEU A 203 -23.814 28.903 103.157 1.00 48.10 C ANISOU 423 CB LEU A 203 6536 6604 5134 -945 -917 270 C ATOM 424 CG LEU A 203 -22.414 29.295 102.709 1.00 45.87 C ANISOU 424 CG LEU A 203 6532 6146 4747 -844 -790 159 C ATOM 425 CD1 LEU A 203 -21.708 29.958 103.871 1.00 46.97 C ANISOU 425 CD1 LEU A 203 6629 6277 4940 -731 -584 168 C ATOM 426 CD2 LEU A 203 -21.591 28.155 102.147 1.00 46.35 C ANISOU 426 CD2 LEU A 203 6818 6039 4752 -948 -817 50 C ATOM 427 N SER A 204 -27.122 27.698 102.490 1.00 54.22 N ANISOU 427 N SER A 204 6737 7806 6057 -1353 -1459 526 N ATOM 428 CA SER A 204 -28.341 27.265 103.217 1.00 58.68 C ANISOU 428 CA SER A 204 6895 8633 6766 -1520 -1522 713 C ATOM 429 C SER A 204 -28.254 25.881 103.795 1.00 58.96 C ANISOU 429 C SER A 204 6946 8547 6905 -1840 -1553 754 C ATOM 430 O SER A 204 -28.594 25.657 104.969 1.00 62.03 O ANISOU 430 O SER A 204 7085 9085 7396 -1897 -1410 902 O ATOM 431 CB SER A 204 -29.547 27.253 102.292 1.00 64.37 C ANISOU 431 CB SER A 204 7413 9554 7488 -1632 -1821 794 C ATOM 432 OG SER A 204 -29.718 28.525 101.754 1.00 67.89 O ANISOU 432 OG SER A 204 7849 10112 7833 -1318 -1813 781 O ATOM 433 N SER A 205 -27.799 24.949 102.970 1.00 57.78 N ANISOU 433 N SER A 205 7124 8118 6709 -2032 -1740 627 N ATOM 434 CA SER A 205 -27.718 23.541 103.363 1.00 59.44 C ANISOU 434 CA SER A 205 7441 8133 7009 -2348 -1828 653 C ATOM 435 C SER A 205 -26.294 23.124 103.868 1.00 55.08 C ANISOU 435 C SER A 205 7224 7285 6416 -2233 -1625 524 C ATOM 436 O SER A 205 -26.050 21.932 104.070 1.00 56.86 O ANISOU 436 O SER A 205 7642 7274 6687 -2441 -1710 516 O ATOM 437 CB SER A 205 -28.147 22.694 102.168 1.00 62.59 C ANISOU 437 CB SER A 205 8039 8374 7369 -2619 -2200 579 C ATOM 438 OG SER A 205 -27.052 22.597 101.275 1.00 61.96 O ANISOU 438 OG SER A 205 8425 8001 7113 -2457 -2207 339 O ATOM 439 N PHE A 206 -25.395 24.094 104.095 1.00 50.21 N ANISOU 439 N PHE A 206 6668 6683 5724 -1913 -1380 441 N ATOM 440 CA PHE A 206 -23.974 23.827 104.468 1.00 47.10 C ANISOU 440 CA PHE A 206 6548 6062 5285 -1776 -1201 320 C ATOM 441 C PHE A 206 -23.898 23.583 105.949 1.00 45.78 C ANISOU 441 C PHE A 206 6223 5951 5219 -1798 -1031 446 C ATOM 442 O PHE A 206 -24.328 24.432 106.714 1.00 45.55 O ANISOU 442 O PHE A 206 5926 6162 5218 -1688 -890 550 O ATOM 443 CB PHE A 206 -23.085 25.009 104.120 1.00 45.76 C ANISOU 443 CB PHE A 206 6467 5914 5004 -1483 -1033 213 C ATOM 444 CG PHE A 206 -21.605 24.795 104.387 1.00 44.58 C ANISOU 444 CG PHE A 206 6540 5589 4809 -1348 -866 102 C ATOM 445 CD1 PHE A 206 -20.851 23.949 103.578 1.00 45.87 C ANISOU 445 CD1 PHE A 206 7011 5535 4882 -1344 -932 -36 C ATOM 446 CD2 PHE A 206 -20.969 25.456 105.414 1.00 42.52 C ANISOU 446 CD2 PHE A 206 6179 5396 4579 -1204 -656 130 C ATOM 447 CE1 PHE A 206 -19.498 23.759 103.799 1.00 44.89 C ANISOU 447 CE1 PHE A 206 7038 5304 4714 -1185 -772 -122 C ATOM 448 CE2 PHE A 206 -19.593 25.304 105.632 1.00 43.21 C ANISOU 448 CE2 PHE A 206 6420 5366 4630 -1086 -525 43 C ATOM 449 CZ PHE A 206 -18.859 24.452 104.831 1.00 43.73 C ANISOU 449 CZ PHE A 206 6736 5256 4622 -1069 -572 -72 C ATOM 450 N ASP A 207 -23.380 22.430 106.338 1.00 45.83 N ANISOU 450 N ASP A 207 6422 5732 5257 -1916 -1052 436 N ATOM 451 CA ASP A 207 -23.222 22.078 107.749 1.00 46.41 C ANISOU 451 CA ASP A 207 6398 5834 5400 -1937 -902 566 C ATOM 452 C ASP A 207 -21.859 22.587 108.228 1.00 42.89 C ANISOU 452 C ASP A 207 6076 5332 4886 -1654 -696 453 C ATOM 453 O ASP A 207 -20.810 21.991 107.928 1.00 41.31 O ANISOU 453 O ASP A 207 6150 4902 4643 -1581 -705 329 O ATOM 454 CB ASP A 207 -23.370 20.559 107.976 1.00 50.23 C ANISOU 454 CB ASP A 207 7052 6079 5954 -2215 -1051 642 C ATOM 455 CG ASP A 207 -23.274 20.171 109.477 1.00 52.77 C ANISOU 455 CG ASP A 207 7279 6443 6328 -2247 -894 818 C ATOM 456 OD1 ASP A 207 -22.214 20.278 110.098 1.00 54.12 O ANISOU 456 OD1 ASP A 207 7569 6544 6447 -2029 -741 754 O ATOM 457 OD2 ASP A 207 -24.279 19.763 110.027 1.00 60.09 O ANISOU 457 OD2 ASP A 207 7997 7496 7336 -2498 -931 1037 O ATOM 458 N PHE A 208 -21.864 23.730 108.921 1.00 42.90 N ANISOU 458 N PHE A 208 5880 5550 4869 -1480 -525 489 N ATOM 459 CA PHE A 208 -20.621 24.410 109.338 1.00 39.97 C ANISOU 459 CA PHE A 208 5598 5149 4437 -1246 -366 385 C ATOM 460 C PHE A 208 -19.698 23.445 110.087 1.00 39.86 C ANISOU 460 C PHE A 208 5735 4975 4433 -1243 -328 385 C ATOM 461 O PHE A 208 -18.513 23.365 109.815 1.00 39.94 O ANISOU 461 O PHE A 208 5907 4863 4402 -1115 -297 265 O ATOM 462 CB PHE A 208 -20.954 25.660 110.180 1.00 40.74 C ANISOU 462 CB PHE A 208 5495 5471 4510 -1094 -228 438 C ATOM 463 CG PHE A 208 -19.758 26.492 110.555 1.00 37.56 C ANISOU 463 CG PHE A 208 5189 5031 4050 -904 -116 331 C ATOM 464 CD1 PHE A 208 -19.294 27.486 109.692 1.00 37.59 C ANISOU 464 CD1 PHE A 208 5266 5006 4010 -805 -116 228 C ATOM 465 CD2 PHE A 208 -19.113 26.314 111.773 1.00 37.22 C ANISOU 465 CD2 PHE A 208 5162 4988 3991 -844 -28 352 C ATOM 466 CE1 PHE A 208 -18.218 28.294 110.036 1.00 36.64 C ANISOU 466 CE1 PHE A 208 5215 4852 3852 -688 -36 155 C ATOM 467 CE2 PHE A 208 -18.013 27.117 112.107 1.00 37.76 C ANISOU 467 CE2 PHE A 208 5301 5031 4012 -705 32 256 C ATOM 468 CZ PHE A 208 -17.552 28.088 111.234 1.00 37.18 C ANISOU 468 CZ PHE A 208 5285 4923 3918 -648 25 161 C ATOM 469 N ARG A 209 -20.244 22.693 111.019 1.00 40.93 N ANISOU 469 N ARG A 209 5806 5127 4616 -1377 -330 539 N ATOM 470 CA ARG A 209 -19.430 21.786 111.749 1.00 44.56 C ANISOU 470 CA ARG A 209 6428 5427 5075 -1356 -310 560 C ATOM 471 C ARG A 209 -18.716 20.694 110.931 1.00 45.06 C ANISOU 471 C ARG A 209 6794 5188 5139 -1367 -437 450 C ATOM 472 O ARG A 209 -17.571 20.378 111.241 1.00 45.20 O ANISOU 472 O ARG A 209 6952 5099 5123 -1198 -390 385 O ATOM 473 CB ARG A 209 -20.214 21.156 112.900 1.00 48.14 C ANISOU 473 CB ARG A 209 6777 5951 5562 -1518 -285 785 C ATOM 474 CG ARG A 209 -19.336 20.266 113.746 1.00 49.92 C ANISOU 474 CG ARG A 209 7195 6004 5766 -1467 -268 825 C ATOM 475 CD ARG A 209 -19.991 19.950 115.058 1.00 52.13 C ANISOU 475 CD ARG A 209 7355 6419 6032 -1574 -186 1064 C ATOM 476 NE ARG A 209 -19.794 21.039 115.992 1.00 51.55 N ANISOU 476 NE ARG A 209 7126 6601 5860 -1363 -16 1057 N ATOM 477 CZ ARG A 209 -18.671 21.253 116.669 1.00 49.84 C ANISOU 477 CZ ARG A 209 7016 6357 5563 -1153 34 979 C ATOM 478 NH1 ARG A 209 -17.597 20.487 116.488 1.00 50.88 N ANISOU 478 NH1 ARG A 209 7370 6251 5710 -1088 -48 906 N ATOM 479 NH2 ARG A 209 -18.605 22.271 117.486 1.00 46.97 N ANISOU 479 NH2 ARG A 209 6540 6208 5097 -988 152 962 N ATOM 480 N THR A 210 -19.398 20.078 109.969 1.00 44.83 N ANISOU 480 N THR A 210 6870 5025 5137 -1551 -608 433 N ATOM 481 CA THR A 210 -18.787 18.979 109.206 1.00 48.05 C ANISOU 481 CA THR A 210 7630 5111 5513 -1533 -743 310 C ATOM 482 C THR A 210 -18.155 19.441 107.887 1.00 47.42 C ANISOU 482 C THR A 210 7673 5010 5332 -1352 -746 98 C ATOM 483 O THR A 210 -17.400 18.694 107.276 1.00 49.15 O ANISOU 483 O THR A 210 8184 5007 5481 -1225 -799 -35 O ATOM 484 CB THR A 210 -19.808 17.906 108.817 1.00 50.04 C ANISOU 484 CB THR A 210 8024 5162 5826 -1853 -978 385 C ATOM 485 OG1 THR A 210 -20.852 18.509 108.071 1.00 49.50 O ANISOU 485 OG1 THR A 210 7770 5264 5773 -2011 -1070 397 O ATOM 486 CG2 THR A 210 -20.431 17.273 110.067 1.00 53.10 C ANISOU 486 CG2 THR A 210 8317 5551 6308 -2079 -977 637 C ATOM 487 N GLY A 211 -18.522 20.632 107.423 1.00 44.11 N ANISOU 487 N GLY A 211 7052 4817 4890 -1329 -691 80 N ATOM 488 CA GLY A 211 -18.026 21.129 106.168 1.00 43.95 C ANISOU 488 CA GLY A 211 7142 4801 4756 -1186 -685 -78 C ATOM 489 C GLY A 211 -18.636 20.456 104.958 1.00 47.48 C ANISOU 489 C GLY A 211 7816 5085 5140 -1311 -905 -163 C ATOM 490 O GLY A 211 -18.009 20.435 103.910 1.00 49.14 O ANISOU 490 O GLY A 211 8236 5225 5210 -1155 -906 -317 O ATOM 491 N LYS A 212 -19.862 19.970 105.090 1.00 48.72 N ANISOU 491 N LYS A 212 7914 5209 5384 -1596 -1090 -55 N ATOM 492 CA LYS A 212 -20.556 19.242 104.044 1.00 53.50 C ANISOU 492 CA LYS A 212 8740 5640 5944 -1782 -1364 -124 C ATOM 493 C LYS A 212 -21.913 19.918 103.815 1.00 55.91 C ANISOU 493 C LYS A 212 8744 6189 6310 -1991 -1480 -4 C ATOM 494 O LYS A 212 -22.514 20.490 104.745 1.00 52.61 O ANISOU 494 O LYS A 212 7970 6012 6007 -2054 -1375 173 O ATOM 495 CB LYS A 212 -20.744 17.768 104.438 1.00 55.60 C ANISOU 495 CB LYS A 212 9253 5590 6281 -1991 -1542 -85 C ATOM 496 CG LYS A 212 -19.439 17.005 104.602 1.00 56.28 C ANISOU 496 CG LYS A 212 9672 5416 6295 -1736 -1458 -209 C ATOM 497 N MET A 213 -22.370 19.864 102.563 1.00 57.64 N ANISOU 497 N MET A 213 9111 6360 6429 -2060 -1697 -106 N ATOM 498 CA MET A 213 -23.741 20.211 102.215 1.00 62.72 C ANISOU 498 CA MET A 213 9500 7200 7127 -2291 -1896 6 C ATOM 499 C MET A 213 -24.578 19.023 102.652 1.00 66.34 C ANISOU 499 C MET A 213 9957 7518 7728 -2679 -2127 133 C ATOM 500 O MET A 213 -24.099 17.882 102.677 1.00 69.53 O ANISOU 500 O MET A 213 10720 7577 8121 -2755 -2224 56 O ATOM 501 CB MET A 213 -23.880 20.489 100.710 1.00 64.72 C ANISOU 501 CB MET A 213 9954 7437 7200 -2233 -2081 -149 C ATOM 502 CG MET A 213 -22.986 21.614 100.203 1.00 61.66 C ANISOU 502 CG MET A 213 9608 7163 6655 -1878 -1849 -248 C ATOM 503 SD MET A 213 -23.546 23.267 100.680 1.00 64.00 S ANISOU 503 SD MET A 213 9448 7840 7027 -1762 -1678 -79 S ATOM 504 CE MET A 213 -22.290 24.372 100.018 1.00 60.50 C ANISOU 504 CE MET A 213 9176 7417 6395 -1416 -1437 -192 C ATOM 505 N MET A 214 -25.803 19.284 103.074 1.00 69.41 N ANISOU 505 N MET A 214 9937 8178 8256 -2917 -2200 349 N ATOM 506 CA MET A 214 -26.704 18.202 103.515 1.00 72.87 C ANISOU 506 CA MET A 214 10303 8533 8848 -3358 -2421 530 C ATOM 507 C MET A 214 -27.950 18.115 102.617 1.00 77.15 C ANISOU 507 C MET A 214 10701 9194 9417 -3669 -2780 582 C ATOM 508 O MET A 214 -28.360 19.105 102.046 1.00 76.68 O ANISOU 508 O MET A 214 10419 9415 9298 -3522 -2787 566 O ATOM 509 CB MET A 214 -27.015 18.399 105.006 1.00 72.13 C ANISOU 509 CB MET A 214 9816 8688 8900 -3403 -2169 793 C ATOM 510 CG MET A 214 -25.781 18.246 105.907 1.00 66.98 C ANISOU 510 CG MET A 214 9367 7867 8216 -3152 -1893 742 C ATOM 511 N PRO A 215 -28.534 16.914 102.463 1.00 83.59 N ANISOU 511 N PRO A 215 11669 9775 10316 -4108 -3109 644 N TER 512 PRO A 215 ATOM 513 O5' DG B 1 -32.007 17.911 130.431 1.00 65.07 O ANISOU 513 O5' DG B 1 6544 9474 8704 -2366 -163 2575 O ATOM 514 C5' DG B 1 -30.690 18.405 130.584 1.00 62.74 C ANISOU 514 C5' DG B 1 6363 9109 8365 -2210 -148 2503 C ATOM 515 C4' DG B 1 -29.998 18.332 129.244 1.00 62.45 C ANISOU 515 C4' DG B 1 6508 8601 8618 -1997 -175 2216 C ATOM 516 O4' DG B 1 -30.596 19.259 128.307 1.00 59.10 O ANISOU 516 O4' DG B 1 6155 8237 8060 -1857 -70 1854 O ATOM 517 C3' DG B 1 -28.518 18.673 129.262 1.00 60.53 C ANISOU 517 C3' DG B 1 6371 8206 8421 -1833 -172 2148 C ATOM 518 O3' DG B 1 -28.016 17.907 128.179 1.00 64.84 O ANISOU 518 O3' DG B 1 7004 8260 9371 -1766 -228 2003 O ATOM 519 C2' DG B 1 -28.511 20.164 128.996 1.00 56.89 C ANISOU 519 C2' DG B 1 5993 7983 7637 -1650 -16 1814 C ATOM 520 C1' DG B 1 -29.702 20.326 128.046 1.00 55.12 C ANISOU 520 C1' DG B 1 5774 7747 7423 -1647 12 1612 C ATOM 521 N9 DG B 1 -30.445 21.576 128.169 1.00 52.51 N ANISOU 521 N9 DG B 1 5378 7738 6834 -1572 128 1437 N ATOM 522 C8 DG B 1 -30.746 22.276 129.315 1.00 52.55 C ANISOU 522 C8 DG B 1 5244 8136 6585 -1605 244 1466 C ATOM 523 N7 DG B 1 -31.395 23.383 129.082 1.00 51.37 N ANISOU 523 N7 DG B 1 5025 8132 6358 -1492 343 1225 N ATOM 524 C5 DG B 1 -31.513 23.428 127.699 1.00 49.68 C ANISOU 524 C5 DG B 1 4925 7629 6320 -1400 248 1096 C ATOM 525 C6 DG B 1 -32.122 24.399 126.857 1.00 45.99 C ANISOU 525 C6 DG B 1 4426 7144 5904 -1288 237 902 C ATOM 526 O6 DG B 1 -32.721 25.427 127.183 1.00 43.89 O ANISOU 526 O6 DG B 1 3996 7058 5621 -1204 322 779 O ATOM 527 N1 DG B 1 -32.035 24.039 125.511 1.00 44.49 N ANISOU 527 N1 DG B 1 4386 6689 5829 -1311 101 862 N ATOM 528 C2 DG B 1 -31.410 22.905 125.035 1.00 46.11 C ANISOU 528 C2 DG B 1 4745 6653 6121 -1404 38 908 C ATOM 529 N2 DG B 1 -31.407 22.729 123.704 1.00 45.30 N ANISOU 529 N2 DG B 1 4771 6366 6075 -1462 -52 784 N ATOM 530 N3 DG B 1 -30.838 21.998 125.812 1.00 48.76 N ANISOU 530 N3 DG B 1 5083 6931 6511 -1462 54 1064 N ATOM 531 C4 DG B 1 -30.938 22.315 127.122 1.00 50.21 C ANISOU 531 C4 DG B 1 5131 7394 6550 -1466 137 1192 C ATOM 532 P DC B 2 -26.450 17.752 127.931 1.00 69.77 P ANISOU 532 P DC B 2 7691 8550 10267 -1617 -244 1930 P ATOM 533 OP1 DC B 2 -26.214 16.303 127.765 1.00 69.71 O ANISOU 533 OP1 DC B 2 7592 8083 10812 -1709 -377 2087 O ATOM 534 OP2 DC B 2 -25.704 18.560 128.946 1.00 69.56 O ANISOU 534 OP2 DC B 2 7644 8816 9967 -1569 -232 2080 O ATOM 535 O5' DC B 2 -26.238 18.449 126.514 1.00 60.54 O ANISOU 535 O5' DC B 2 6699 7271 9029 -1454 -107 1435 O ATOM 536 C5' DC B 2 -26.941 17.917 125.376 1.00 61.73 C ANISOU 536 C5' DC B 2 6905 7228 9320 -1532 -98 1204 C ATOM 537 C4' DC B 2 -26.858 18.886 124.224 1.00 60.58 C ANISOU 537 C4' DC B 2 6920 7164 8932 -1446 6 821 C ATOM 538 O4' DC B 2 -27.603 20.078 124.561 1.00 57.21 O ANISOU 538 O4' DC B 2 6485 7127 8123 -1405 23 866 O ATOM 539 C3' DC B 2 -25.434 19.347 123.900 1.00 60.56 C ANISOU 539 C3' DC B 2 7000 7049 8958 -1292 95 625 C ATOM 540 O3' DC B 2 -25.172 19.144 122.514 1.00 66.04 O ANISOU 540 O3' DC B 2 7805 7560 9726 -1341 176 246 O ATOM 541 C2' DC B 2 -25.408 20.805 124.319 1.00 55.63 C ANISOU 541 C2' DC B 2 6417 6779 7940 -1175 128 649 C ATOM 542 C1' DC B 2 -26.859 21.203 124.161 1.00 54.64 C ANISOU 542 C1' DC B 2 6267 6884 7608 -1260 93 670 C ATOM 543 N1 DC B 2 -27.316 22.344 124.966 1.00 51.47 N ANISOU 543 N1 DC B 2 5798 6817 6938 -1184 115 760 N ATOM 544 C2 DC B 2 -27.979 23.403 124.321 1.00 47.48 C ANISOU 544 C2 DC B 2 5313 6456 6269 -1149 112 618 C ATOM 545 O2 DC B 2 -28.197 23.322 123.094 1.00 45.70 O ANISOU 545 O2 DC B 2 5176 6126 6061 -1224 64 474 O ATOM 546 N3 DC B 2 -28.430 24.442 125.057 1.00 43.27 N ANISOU 546 N3 DC B 2 4675 6174 5592 -1066 152 644 N ATOM 547 C4 DC B 2 -28.238 24.458 126.378 1.00 45.96 C ANISOU 547 C4 DC B 2 4920 6688 5854 -1056 217 770 C ATOM 548 N4 DC B 2 -28.698 25.503 127.062 1.00 45.77 N ANISOU 548 N4 DC B 2 4779 6918 5693 -996 298 705 N ATOM 549 C5 DC B 2 -27.536 23.413 127.054 1.00 48.90 C ANISOU 549 C5 DC B 2 5293 6978 6307 -1133 194 968 C ATOM 550 C6 DC B 2 -27.120 22.373 126.320 1.00 50.45 C ANISOU 550 C6 DC B 2 5567 6859 6743 -1178 131 974 C ATOM 551 P DC B 3 -23.690 19.422 121.903 1.00 66.08 P ANISOU 551 P DC B 3 7877 7420 9807 -1232 309 -41 P ATOM 552 OP1 DC B 3 -23.272 18.193 121.225 1.00 71.02 O ANISOU 552 OP1 DC B 3 8459 7656 10869 -1313 383 -299 O ATOM 553 OP2 DC B 3 -22.817 20.047 122.946 1.00 60.95 O ANISOU 553 OP2 DC B 3 7177 6865 9114 -1059 293 180 O ATOM 554 O5' DC B 3 -23.995 20.563 120.829 1.00 61.19 O ANISOU 554 O5' DC B 3 7418 7080 8750 -1289 353 -278 O ATOM 555 C5' DC B 3 -25.209 20.633 120.035 1.00 57.53 C ANISOU 555 C5' DC B 3 7014 6759 8084 -1476 289 -347 C ATOM 556 C4' DC B 3 -25.396 22.070 119.605 1.00 56.07 C ANISOU 556 C4' DC B 3 6912 6877 7511 -1462 247 -344 C ATOM 557 O4' DC B 3 -25.786 22.826 120.772 1.00 52.40 O ANISOU 557 O4' DC B 3 6358 6576 6975 -1297 182 -60 O ATOM 558 C3' DC B 3 -24.102 22.727 119.107 1.00 54.69 C ANISOU 558 C3' DC B 3 6828 6721 7230 -1402 353 -537 C ATOM 559 O3' DC B 3 -24.070 22.941 117.695 1.00 61.29 O ANISOU 559 O3' DC B 3 7781 7664 7839 -1627 379 -793 O ATOM 560 C2' DC B 3 -23.995 24.029 119.887 1.00 50.59 C ANISOU 560 C2' DC B 3 6288 6389 6544 -1216 293 -324 C ATOM 561 C1' DC B 3 -25.277 24.148 120.679 1.00 49.22 C ANISOU 561 C1' DC B 3 6008 6329 6365 -1190 185 -81 C ATOM 562 N1 DC B 3 -25.143 24.663 122.056 1.00 46.45 N ANISOU 562 N1 DC B 3 5561 6070 6016 -1009 194 109 N ATOM 563 C2 DC B 3 -25.746 25.877 122.416 1.00 43.43 C ANISOU 563 C2 DC B 3 5120 5888 5493 -931 146 181 C ATOM 564 O2 DC B 3 -26.284 26.564 121.543 1.00 44.44 O ANISOU 564 O2 DC B 3 5270 6076 5537 -991 61 139 O ATOM 565 N3 DC B 3 -25.664 26.301 123.699 1.00 43.80 N ANISOU 565 N3 DC B 3 5071 6054 5515 -813 190 284 N ATOM 566 C4 DC B 3 -25.060 25.540 124.614 1.00 44.67 C ANISOU 566 C4 DC B 3 5150 6127 5694 -804 234 394 C ATOM 567 N4 DC B 3 -25.042 25.972 125.871 1.00 47.04 N ANISOU 567 N4 DC B 3 5357 6620 5894 -758 271 497 N ATOM 568 C5 DC B 3 -24.450 24.299 124.278 1.00 45.92 C ANISOU 568 C5 DC B 3 5347 6044 6055 -866 237 400 C ATOM 569 C6 DC B 3 -24.514 23.902 122.999 1.00 46.13 C ANISOU 569 C6 DC B 3 5461 5919 6145 -952 237 219 C ATOM 570 P DT B 4 -22.737 23.609 116.999 1.00 63.43 P ANISOU 570 P DT B 4 8139 8010 7948 -1641 506 -1014 P ATOM 571 OP1 DT B 4 -22.546 22.952 115.692 1.00 68.66 O ANISOU 571 OP1 DT B 4 8875 8681 8530 -1936 632 -1396 O ATOM 572 OP2 DT B 4 -21.594 23.571 117.969 1.00 54.68 O ANISOU 572 OP2 DT B 4 6957 6735 7084 -1378 603 -966 O ATOM 573 O5' DT B 4 -23.240 25.112 116.740 1.00 59.95 O ANISOU 573 O5' DT B 4 7749 7859 7167 -1672 328 -796 O ATOM 574 C5' DT B 4 -24.616 25.380 116.352 1.00 55.94 C ANISOU 574 C5' DT B 4 7231 7499 6522 -1829 131 -632 C ATOM 575 C4' DT B 4 -24.927 26.859 116.458 1.00 53.14 C ANISOU 575 C4' DT B 4 6847 7305 6037 -1754 -46 -376 C ATOM 576 O4' DT B 4 -24.984 27.327 117.840 1.00 48.24 O ANISOU 576 O4' DT B 4 6114 6614 5600 -1440 -42 -207 O ATOM 577 C3' DT B 4 -23.952 27.792 115.739 1.00 51.75 C ANISOU 577 C3' DT B 4 6762 7253 5646 -1837 -46 -425 C ATOM 578 O3' DT B 4 -24.769 28.712 115.017 1.00 55.77 O ANISOU 578 O3' DT B 4 7256 7937 5997 -2022 -301 -203 O ATOM 579 C2' DT B 4 -23.166 28.447 116.862 1.00 48.00 C ANISOU 579 C2' DT B 4 6239 6684 5314 -1513 17 -351 C ATOM 580 C1' DT B 4 -24.127 28.434 118.059 1.00 45.65 C ANISOU 580 C1' DT B 4 5805 6319 5220 -1304 -39 -174 C ATOM 581 N1 DT B 4 -23.557 28.263 119.425 1.00 42.33 N ANISOU 581 N1 DT B 4 5325 5802 4957 -1049 83 -160 N ATOM 582 C2 DT B 4 -23.956 29.108 120.440 1.00 39.60 C ANISOU 582 C2 DT B 4 4870 5502 4672 -871 38 -28 C ATOM 583 O2 DT B 4 -24.653 30.081 120.259 1.00 38.15 O ANISOU 583 O2 DT B 4 4619 5379 4495 -865 -89 58 O ATOM 584 N3 DT B 4 -23.472 28.783 121.682 1.00 38.66 N ANISOU 584 N3 DT B 4 4701 5356 4630 -721 146 -9 N ATOM 585 C4 DT B 4 -22.668 27.712 122.007 1.00 40.96 C ANISOU 585 C4 DT B 4 5017 5538 5008 -715 248 -41 C ATOM 586 O4 DT B 4 -22.310 27.548 123.164 1.00 41.01 O ANISOU 586 O4 DT B 4 4957 5556 5067 -618 288 52 O ATOM 587 C5 DT B 4 -22.281 26.872 120.900 1.00 42.94 C ANISOU 587 C5 DT B 4 5351 5668 5295 -854 296 -196 C ATOM 588 C7 DT B 4 -21.370 25.713 121.159 1.00 44.72 C ANISOU 588 C7 DT B 4 5552 5692 5745 -829 406 -262 C ATOM 589 C6 DT B 4 -22.761 27.168 119.684 1.00 44.21 C ANISOU 589 C6 DT B 4 5584 5903 5311 -1025 232 -277 C ATOM 590 P DA B 5 -24.108 29.696 113.910 1.00 57.24 P ANISOU 590 P DA B 5 7531 8329 5887 -2272 -406 -152 P ATOM 591 OP1 DA B 5 -25.185 30.090 113.021 1.00 53.54 O ANISOU 591 OP1 DA B 5 7031 8032 5277 -2573 -697 87 O ATOM 592 OP2 DA B 5 -22.710 29.213 113.476 1.00 54.23 O ANISOU 592 OP2 DA B 5 7266 7986 5351 -2364 -139 -483 O ATOM 593 O5' DA B 5 -23.594 30.957 114.744 1.00 48.32 O ANISOU 593 O5' DA B 5 6333 7104 4920 -1969 -461 24 O ATOM 594 C5' DA B 5 -24.524 31.833 115.433 1.00 46.49 C ANISOU 594 C5' DA B 5 5941 6781 4941 -1770 -657 285 C ATOM 595 C4' DA B 5 -23.770 32.724 116.392 1.00 42.42 C ANISOU 595 C4' DA B 5 5382 6146 4589 -1471 -596 292 C ATOM 596 O4' DA B 5 -23.306 31.944 117.526 1.00 38.22 O ANISOU 596 O4' DA B 5 4854 5514 4153 -1232 -349 107 O ATOM 597 C3' DA B 5 -22.537 33.414 115.791 1.00 42.08 C ANISOU 597 C3' DA B 5 5445 6174 4369 -1579 -598 285 C ATOM 598 O3' DA B 5 -22.836 34.801 115.556 1.00 43.13 O ANISOU 598 O3' DA B 5 5485 6280 4621 -1600 -870 558 O ATOM 599 C2' DA B 5 -21.429 33.190 116.809 1.00 39.59 C ANISOU 599 C2' DA B 5 5158 5756 4126 -1317 -354 94 C ATOM 600 C1' DA B 5 -22.120 32.565 118.024 1.00 37.38 C ANISOU 600 C1' DA B 5 4781 5366 4054 -1081 -262 53 C ATOM 601 N9 DA B 5 -21.335 31.536 118.719 1.00 36.97 N ANISOU 601 N9 DA B 5 4766 5253 4028 -966 -33 -116 N ATOM 602 C8 DA B 5 -20.671 30.473 118.171 1.00 37.19 C ANISOU 602 C8 DA B 5 4874 5268 3989 -1085 117 -294 C ATOM 603 N7 DA B 5 -20.107 29.687 119.054 1.00 37.13 N ANISOU 603 N7 DA B 5 4830 5141 4136 -930 263 -364 N ATOM 604 C5 DA B 5 -20.460 30.245 120.270 1.00 36.15 C ANISOU 604 C5 DA B 5 4620 5014 4099 -736 209 -221 C ATOM 605 C6 DA B 5 -20.125 29.906 121.596 1.00 37.85 C ANISOU 605 C6 DA B 5 4764 5186 4428 -574 280 -171 C ATOM 606 N6 DA B 5 -19.369 28.855 121.918 1.00 37.14 N ANISOU 606 N6 DA B 5 4658 4986 4466 -552 380 -201 N ATOM 607 N1 DA B 5 -20.609 30.688 122.587 1.00 35.83 N ANISOU 607 N1 DA B 5 4430 5011 4173 -462 234 -87 N ATOM 608 C2 DA B 5 -21.349 31.759 122.252 1.00 36.25 C ANISOU 608 C2 DA B 5 4451 5107 4213 -462 127 -68 C ATOM 609 N3 DA B 5 -21.703 32.194 121.034 1.00 36.40 N ANISOU 609 N3 DA B 5 4513 5123 4194 -587 7 -44 N ATOM 610 C4 DA B 5 -21.197 31.398 120.082 1.00 35.56 C ANISOU 610 C4 DA B 5 4514 5009 3988 -741 55 -115 C HETATM 611 N1 5CM B 6 -18.876 34.599 119.680 1.00 38.63 N ANISOU 611 N1 5CM B 6 4982 5415 4278 -681 -100 -41 N HETATM 612 C2 5CM B 6 -18.727 34.061 120.975 1.00 36.29 C ANISOU 612 C2 5CM B 6 4637 5085 4066 -500 32 -111 C HETATM 613 N3 5CM B 6 -18.168 32.882 121.170 1.00 33.63 N ANISOU 613 N3 5CM B 6 4325 4733 3717 -498 177 -183 N HETATM 614 C4 5CM B 6 -17.670 32.156 120.153 1.00 34.06 C ANISOU 614 C4 5CM B 6 4447 4787 3707 -642 253 -277 C HETATM 615 C5 5CM B 6 -17.853 32.685 118.749 1.00 35.85 C ANISOU 615 C5 5CM B 6 4746 5112 3762 -868 160 -271 C HETATM 616 C5A 5CM B 6 -17.337 31.936 117.530 1.00 37.43 C ANISOU 616 C5A 5CM B 6 5018 5389 3814 -1105 282 -448 C HETATM 617 C6 5CM B 6 -18.427 33.915 118.599 1.00 36.45 C ANISOU 617 C6 5CM B 6 4799 5215 3832 -884 -38 -108 C HETATM 618 O2 5CM B 6 -19.169 34.704 121.965 1.00 36.12 O ANISOU 618 O2 5CM B 6 4523 5050 4150 -363 7 -103 O HETATM 619 N4 5CM B 6 -17.114 30.966 120.397 1.00 33.01 N ANISOU 619 N4 5CM B 6 4291 4568 3680 -614 397 -369 N HETATM 620 C1' 5CM B 6 -19.480 35.931 119.573 1.00 39.81 C ANISOU 620 C1' 5CM B 6 5054 5515 4554 -668 -306 96 C HETATM 621 C2' 5CM B 6 -18.779 36.881 118.586 1.00 42.23 C ANISOU 621 C2' 5CM B 6 5418 5848 4779 -836 -451 217 C HETATM 622 C3' 5CM B 6 -19.856 37.893 118.401 1.00 43.91 C ANISOU 622 C3' 5CM B 6 5499 5958 5226 -840 -707 407 C HETATM 623 C4' 5CM B 6 -21.118 37.104 118.594 1.00 42.89 C ANISOU 623 C4' 5CM B 6 5294 5837 5164 -807 -686 389 C HETATM 624 O4' 5CM B 6 -20.805 35.798 119.102 1.00 42.52 O ANISOU 624 O4' 5CM B 6 5327 5863 4966 -752 -437 200 O HETATM 625 O3' 5CM B 6 -19.887 38.798 119.489 1.00 47.18 O ANISOU 625 O3' 5CM B 6 5795 6208 5922 -603 -710 343 O HETATM 626 C5' 5CM B 6 -21.970 36.935 117.331 1.00 46.31 C ANISOU 626 C5' 5CM B 6 5722 6357 5515 -1081 -894 590 C HETATM 627 O5' 5CM B 6 -21.144 36.495 116.262 1.00 44.99 O ANISOU 627 O5' 5CM B 6 5724 6375 4995 -1361 -859 579 O HETATM 628 P 5CM B 6 -21.781 35.826 114.968 1.00 46.10 P ANISOU 628 P 5CM B 6 5924 6716 4875 -1731 -966 667 P HETATM 629 OP1 5CM B 6 -22.527 36.939 114.350 1.00 49.22 O ANISOU 629 OP1 5CM B 6 6198 7090 5412 -1884 -1340 1036 O HETATM 630 OP2 5CM B 6 -20.703 35.108 114.194 1.00 42.98 O ANISOU 630 OP2 5CM B 6 5699 6524 4105 -1971 -766 462 O ATOM 631 P DA B 7 -19.099 40.181 119.504 1.00 47.91 P ANISOU 631 P DA B 7 5863 6170 6168 -584 -843 411 P ATOM 632 OP1 DA B 7 -20.049 41.218 119.126 1.00 51.61 O ANISOU 632 OP1 DA B 7 6156 6451 6999 -602 -1123 609 O ATOM 633 OP2 DA B 7 -17.811 40.105 118.765 1.00 47.65 O ANISOU 633 OP2 DA B 7 5988 6268 5847 -765 -820 465 O ATOM 634 O5' DA B 7 -18.724 40.296 121.042 1.00 48.72 O ANISOU 634 O5' DA B 7 5924 6221 6364 -334 -640 145 O ATOM 635 C5' DA B 7 -19.791 40.137 121.984 1.00 48.68 C ANISOU 635 C5' DA B 7 5774 6182 6539 -177 -550 -3 C ATOM 636 C4' DA B 7 -19.211 39.971 123.365 1.00 48.90 C ANISOU 636 C4' DA B 7 5812 6291 6475 -50 -330 -244 C ATOM 637 O4' DA B 7 -18.699 38.622 123.471 1.00 46.59 O ANISOU 637 O4' DA B 7 5650 6176 5875 -99 -181 -235 O ATOM 638 C3' DA B 7 -18.053 40.918 123.697 1.00 47.44 C ANISOU 638 C3' DA B 7 5669 6039 6317 -29 -352 -310 C ATOM 639 O3' DA B 7 -18.218 41.396 125.038 1.00 53.28 O ANISOU 639 O3' DA B 7 6297 6781 7164 84 -225 -577 O ATOM 640 C2' DA B 7 -16.820 40.060 123.472 1.00 45.78 C ANISOU 640 C2' DA B 7 5632 5980 5781 -112 -264 -245 C ATOM 641 C1' DA B 7 -17.298 38.633 123.727 1.00 44.19 C ANISOU 641 C1' DA B 7 5450 5919 5421 -110 -122 -258 C ATOM 642 N9 DA B 7 -16.684 37.598 122.879 1.00 39.60 N ANISOU 642 N9 DA B 7 4986 5404 4657 -218 -78 -167 N ATOM 643 C8 DA B 7 -16.618 37.572 121.508 1.00 39.52 C ANISOU 643 C8 DA B 7 5042 5392 4582 -371 -165 -63 C ATOM 644 N7 DA B 7 -16.074 36.482 121.026 1.00 37.45 N ANISOU 644 N7 DA B 7 4853 5203 4173 -454 -45 -94 N ATOM 645 C5 DA B 7 -15.716 35.762 122.157 1.00 34.42 C ANISOU 645 C5 DA B 7 4438 4828 3811 -328 89 -164 C ATOM 646 C6 DA B 7 -15.091 34.519 122.320 1.00 33.40 C ANISOU 646 C6 DA B 7 4313 4703 3673 -324 227 -202 C ATOM 647 N6 DA B 7 -14.673 33.763 121.300 1.00 33.50 N ANISOU 647 N6 DA B 7 4365 4707 3654 -438 310 -266 N ATOM 648 N1 DA B 7 -14.916 34.061 123.582 1.00 34.77 N ANISOU 648 N1 DA B 7 4424 4890 3896 -226 275 -176 N ATOM 649 C2 DA B 7 -15.354 34.820 124.607 1.00 32.81 C ANISOU 649 C2 DA B 7 4130 4703 3632 -161 230 -177 C ATOM 650 N3 DA B 7 -15.937 36.014 124.575 1.00 33.98 N ANISOU 650 N3 DA B 7 4262 4839 3810 -138 150 -228 N ATOM 651 C4 DA B 7 -16.129 36.415 123.304 1.00 35.29 C ANISOU 651 C4 DA B 7 4474 4935 4000 -209 64 -192 C ATOM 652 P DC B 8 -17.187 42.443 125.710 1.00 51.30 P ANISOU 652 P DC B 8 6055 6466 6968 104 -223 -735 P ATOM 653 OP1 DC B 8 -17.973 43.271 126.641 1.00 58.42 O ANISOU 653 OP1 DC B 8 6762 7275 8159 198 -148 -1044 O ATOM 654 OP2 DC B 8 -16.285 43.094 124.687 1.00 49.91 O ANISOU 654 OP2 DC B 8 5968 6152 6842 23 -415 -525 O ATOM 655 O5' DC B 8 -16.127 41.498 126.460 1.00 48.32 O ANISOU 655 O5' DC B 8 5813 6352 6193 51 -68 -751 O ATOM 656 C5' DC B 8 -16.544 40.478 127.413 1.00 43.28 C ANISOU 656 C5' DC B 8 5151 5945 5348 43 100 -826 C ATOM 657 C4' DC B 8 -15.357 39.608 127.762 1.00 41.63 C ANISOU 657 C4' DC B 8 5053 5902 4860 -28 143 -700 C ATOM 658 O4' DC B 8 -15.077 38.782 126.613 1.00 39.75 O ANISOU 658 O4' DC B 8 4901 5602 4597 -46 98 -489 O ATOM 659 C3' DC B 8 -14.036 40.344 128.070 1.00 41.24 C ANISOU 659 C3' DC B 8 5056 5849 4766 -66 96 -728 C ATOM 660 O3' DC B 8 -13.786 40.391 129.488 1.00 42.99 O ANISOU 660 O3' DC B 8 5237 6286 4810 -139 181 -873 O ATOM 661 C2' DC B 8 -12.976 39.570 127.307 1.00 39.31 C ANISOU 661 C2' DC B 8 4904 5597 4434 -99 62 -500 C ATOM 662 C1' DC B 8 -13.716 38.402 126.658 1.00 37.75 C ANISOU 662 C1' DC B 8 4714 5397 4231 -87 105 -393 C ATOM 663 N1 DC B 8 -13.312 38.057 125.287 1.00 34.89 N ANISOU 663 N1 DC B 8 4420 4943 3893 -123 74 -279 N ATOM 664 C2 DC B 8 -12.698 36.825 125.048 1.00 34.43 C ANISOU 664 C2 DC B 8 4376 4913 3792 -147 154 -200 C ATOM 665 O2 DC B 8 -12.421 36.096 126.008 1.00 33.25 O ANISOU 665 O2 DC B 8 4177 4836 3618 -132 199 -153 O ATOM 666 N3 DC B 8 -12.380 36.476 123.776 1.00 32.22 N ANISOU 666 N3 DC B 8 4141 4583 3515 -215 176 -180 N ATOM 667 C4 DC B 8 -12.673 37.299 122.768 1.00 33.75 C ANISOU 667 C4 DC B 8 4382 4748 3693 -293 88 -169 C ATOM 668 N4 DC B 8 -12.366 36.901 121.530 1.00 33.93 N ANISOU 668 N4 DC B 8 4450 4799 3642 -426 128 -165 N ATOM 669 C5 DC B 8 -13.289 38.570 122.984 1.00 36.05 C ANISOU 669 C5 DC B 8 4652 4976 4067 -265 -48 -164 C ATOM 670 C6 DC B 8 -13.575 38.912 124.249 1.00 35.52 C ANISOU 670 C6 DC B 8 4524 4914 4057 -161 -34 -254 C ATOM 671 P DT B 9 -12.399 40.876 130.133 1.00 41.68 P ANISOU 671 P DT B 9 5112 6208 4514 -232 136 -884 P ATOM 672 OP1 DT B 9 -12.701 41.303 131.516 1.00 43.05 O ANISOU 672 OP1 DT B 9 5216 6605 4534 -342 231 -1151 O ATOM 673 OP2 DT B 9 -11.641 41.819 129.217 1.00 42.42 O ANISOU 673 OP2 DT B 9 5257 6067 4792 -194 14 -848 O ATOM 674 O5' DT B 9 -11.486 39.578 130.133 1.00 40.68 O ANISOU 674 O5' DT B 9 5025 6199 4231 -284 113 -581 O ATOM 675 C5' DT B 9 -12.005 38.346 130.676 1.00 40.68 C ANISOU 675 C5' DT B 9 4983 6367 4105 -332 169 -455 C ATOM 676 C4' DT B 9 -10.967 37.249 130.565 1.00 40.93 C ANISOU 676 C4' DT B 9 5007 6399 4142 -359 109 -158 C ATOM 677 O4' DT B 9 -10.662 36.921 129.189 1.00 38.64 O ANISOU 677 O4' DT B 9 4756 5874 4049 -250 110 -89 O ATOM 678 C3' DT B 9 -9.612 37.498 131.252 1.00 40.76 C ANISOU 678 C3' DT B 9 4965 6487 4034 -464 18 -54 C ATOM 679 O3' DT B 9 -9.279 36.256 131.877 1.00 42.55 O ANISOU 679 O3' DT B 9 5106 6829 4230 -554 -39 237 O ATOM 680 C2' DT B 9 -8.654 37.778 130.094 1.00 38.82 C ANISOU 680 C2' DT B 9 4752 6016 3982 -368 -12 -14 C ATOM 681 C1' DT B 9 -9.233 36.959 128.956 1.00 37.56 C ANISOU 681 C1' DT B 9 4606 5686 3977 -262 59 19 C ATOM 682 N1 DT B 9 -9.067 37.404 127.561 1.00 33.77 N ANISOU 682 N1 DT B 9 4186 5034 3610 -205 81 -50 N ATOM 683 C2 DT B 9 -8.666 36.488 126.613 1.00 34.73 C ANISOU 683 C2 DT B 9 4283 5054 3858 -181 147 13 C ATOM 684 O2 DT B 9 -8.253 35.376 126.900 1.00 34.69 O ANISOU 684 O2 DT B 9 4187 5030 3964 -170 174 131 O ATOM 685 N3 DT B 9 -8.774 36.925 125.306 1.00 31.62 N ANISOU 685 N3 DT B 9 3955 4581 3475 -198 176 -67 N ATOM 686 C4 DT B 9 -9.304 38.132 124.873 1.00 34.32 C ANISOU 686 C4 DT B 9 4370 4899 3768 -225 97 -131 C ATOM 687 O4 DT B 9 -9.352 38.391 123.657 1.00 34.24 O ANISOU 687 O4 DT B 9 4405 4852 3750 -296 91 -130 O ATOM 688 C5 DT B 9 -9.673 39.054 125.933 1.00 35.76 C ANISOU 688 C5 DT B 9 4548 5110 3929 -200 21 -197 C ATOM 689 C7 DT B 9 -10.157 40.423 125.573 1.00 37.68 C ANISOU 689 C7 DT B 9 4816 5246 4253 -209 -83 -271 C ATOM 690 C6 DT B 9 -9.554 38.640 127.203 1.00 34.13 C ANISOU 690 C6 DT B 9 4292 5023 3651 -198 41 -190 C ATOM 691 P DC B 10 -8.186 36.135 133.129 1.00 46.18 P ANISOU 691 P DC B 10 5483 7535 4525 -767 -187 467 P ATOM 692 OP1 DC B 10 -8.590 34.940 133.899 1.00 44.71 O ANISOU 692 OP1 DC B 10 5203 7512 4271 -902 -247 748 O ATOM 693 OP2 DC B 10 -7.914 37.467 133.798 1.00 45.12 O ANISOU 693 OP2 DC B 10 5402 7581 4161 -891 -196 228 O ATOM 694 O5' DC B 10 -6.836 35.783 132.382 1.00 42.60 O ANISOU 694 O5' DC B 10 4965 6850 4368 -667 -263 663 O ATOM 695 C5' DC B 10 -6.763 34.589 131.592 1.00 43.10 C ANISOU 695 C5' DC B 10 4950 6675 4751 -538 -234 820 C ATOM 696 C4' DC B 10 -5.542 34.639 130.707 1.00 42.21 C ANISOU 696 C4' DC B 10 4775 6353 4909 -435 -223 835 C ATOM 697 O4' DC B 10 -5.799 35.549 129.618 1.00 39.27 O ANISOU 697 O4' DC B 10 4538 5882 4500 -343 -102 550 O ATOM 698 C3' DC B 10 -4.260 35.131 131.376 1.00 44.63 C ANISOU 698 C3' DC B 10 4998 6768 5188 -543 -367 987 C ATOM 699 O3' DC B 10 -3.381 34.007 131.400 1.00 49.94 O ANISOU 699 O3' DC B 10 5452 7298 6224 -519 -448 1284 O ATOM 700 C2' DC B 10 -3.758 36.284 130.494 1.00 42.38 C ANISOU 700 C2' DC B 10 4804 6402 4895 -479 -293 753 C ATOM 701 C1' DC B 10 -4.592 36.174 129.221 1.00 38.23 C ANISOU 701 C1' DC B 10 4374 5705 4446 -343 -124 543 C ATOM 702 N1 DC B 10 -4.988 37.394 128.496 1.00 36.96 N ANISOU 702 N1 DC B 10 4363 5518 4161 -327 -76 310 N ATOM 703 C2 DC B 10 -5.046 37.323 127.099 1.00 35.98 C ANISOU 703 C2 DC B 10 4271 5257 4141 -270 34 212 C ATOM 704 O2 DC B 10 -4.530 36.349 126.530 1.00 36.77 O ANISOU 704 O2 DC B 10 4265 5267 4437 -232 125 255 O ATOM 705 N3 DC B 10 -5.514 38.387 126.403 1.00 34.17 N ANISOU 705 N3 DC B 10 4161 5001 3820 -290 28 79 N ATOM 706 C4 DC B 10 -5.993 39.447 127.052 1.00 33.83 C ANISOU 706 C4 DC B 10 4185 4996 3671 -316 -62 -2 C ATOM 707 N4 DC B 10 -6.460 40.461 126.326 1.00 34.21 N ANISOU 707 N4 DC B 10 4310 4954 3733 -329 -102 -91 N ATOM 708 C5 DC B 10 -6.027 39.507 128.486 1.00 34.86 C ANISOU 708 C5 DC B 10 4287 5266 3691 -361 -120 0 C ATOM 709 C6 DC B 10 -5.516 38.473 129.155 1.00 34.43 C ANISOU 709 C6 DC B 10 4135 5303 3644 -387 -133 177 C ATOM 710 P DC B 11 -1.987 34.061 132.169 1.00 52.74 P ANISOU 710 P DC B 11 5626 7735 6677 -642 -655 1584 P ATOM 711 OP1 DC B 11 -1.755 32.732 132.732 1.00 55.40 O ANISOU 711 OP1 DC B 11 5732 7991 7326 -685 -814 1982 O ATOM 712 OP2 DC B 11 -1.942 35.269 133.037 1.00 50.74 O ANISOU 712 OP2 DC B 11 5503 7790 5985 -833 -748 1508 O ATOM 713 O5' DC B 11 -0.947 34.250 130.982 1.00 51.27 O ANISOU 713 O5' DC B 11 5352 7312 6817 -484 -532 1451 O ATOM 714 C5' DC B 11 -0.954 33.365 129.827 1.00 49.84 C ANISOU 714 C5' DC B 11 5070 6839 7026 -305 -343 1331 C ATOM 715 C4' DC B 11 -0.217 34.024 128.680 1.00 49.08 C ANISOU 715 C4' DC B 11 4980 6671 6997 -240 -174 1084 C ATOM 716 O4' DC B 11 -1.042 35.132 128.200 1.00 43.82 O ANISOU 716 O4' DC B 11 4594 6123 5930 -268 -94 822 O ATOM 717 C3' DC B 11 1.149 34.631 129.035 1.00 50.86 C ANISOU 717 C3' DC B 11 5067 6967 7290 -311 -293 1230 C ATOM 718 O3' DC B 11 2.187 34.621 128.032 1.00 56.41 O ANISOU 718 O3' DC B 11 5602 7541 8287 -244 -133 1107 O ATOM 719 C2' DC B 11 0.859 36.119 129.058 1.00 48.28 C ANISOU 719 C2' DC B 11 4997 6833 6513 -406 -315 1060 C ATOM 720 C1' DC B 11 -0.174 36.199 127.935 1.00 43.18 C ANISOU 720 C1' DC B 11 4530 6111 5765 -325 -109 769 C ATOM 721 N1 DC B 11 -0.963 37.431 127.835 1.00 39.86 N ANISOU 721 N1 DC B 11 4357 5792 4996 -380 -126 596 N ATOM 722 C2 DC B 11 -1.361 37.871 126.563 1.00 38.09 C ANISOU 722 C2 DC B 11 4245 5510 4715 -363 9 397 C ATOM 723 O2 DC B 11 -1.038 37.203 125.567 1.00 38.15 O ANISOU 723 O2 DC B 11 4163 5438 4895 -329 172 326 O ATOM 724 N3 DC B 11 -2.044 39.033 126.450 1.00 35.34 N ANISOU 724 N3 DC B 11 4075 5197 4152 -411 -48 287 N ATOM 725 C4 DC B 11 -2.335 39.742 127.540 1.00 35.64 C ANISOU 725 C4 DC B 11 4179 5315 4046 -456 -183 285 C ATOM 726 N4 DC B 11 -2.990 40.886 127.382 1.00 34.30 N ANISOU 726 N4 DC B 11 4140 5113 3777 -484 -230 143 N ATOM 727 C5 DC B 11 -1.945 39.315 128.849 1.00 37.33 C ANISOU 727 C5 DC B 11 4303 5649 4229 -507 -284 428 C ATOM 728 C6 DC B 11 -1.254 38.176 128.945 1.00 39.34 C ANISOU 728 C6 DC B 11 4383 5876 4686 -476 -278 622 C ATOM 729 P DG B 12 3.312 33.479 127.970 1.00 59.36 P ANISOU 729 P DG B 12 5569 7682 9301 -153 -116 1266 P ATOM 730 OP1 DG B 12 2.605 32.207 127.761 1.00 63.38 O ANISOU 730 OP1 DG B 12 6000 7968 10113 -43 -27 1229 O ATOM 731 OP2 DG B 12 4.222 33.637 129.101 1.00 61.61 O ANISOU 731 OP2 DG B 12 5679 8050 9677 -251 -405 1646 O ATOM 732 O5' DG B 12 4.120 33.914 126.660 1.00 60.14 O ANISOU 732 O5' DG B 12 5592 7759 9498 -129 154 958 O ATOM 733 C5' DG B 12 3.547 33.663 125.362 1.00 58.03 C ANISOU 733 C5' DG B 12 5417 7437 9192 -90 462 579 C ATOM 734 C4' DG B 12 3.744 34.814 124.397 1.00 56.12 C ANISOU 734 C4' DG B 12 5339 7392 8591 -210 601 358 C ATOM 735 O4' DG B 12 2.708 35.798 124.587 1.00 52.59 O ANISOU 735 O4' DG B 12 5245 7099 7638 -289 468 370 O ATOM 736 C3' DG B 12 5.058 35.578 124.468 1.00 57.50 C ANISOU 736 C3' DG B 12 5363 7666 8817 -289 550 459 C ATOM 737 O3' DG B 12 5.928 35.162 123.420 1.00 64.00 O ANISOU 737 O3' DG B 12 5928 8451 9938 -291 847 223 O ATOM 738 C2' DG B 12 4.676 37.021 124.188 1.00 53.16 C ANISOU 738 C2' DG B 12 5124 7325 7747 -440 477 420 C ATOM 739 C1' DG B 12 3.158 37.041 124.111 1.00 49.47 C ANISOU 739 C1' DG B 12 4949 6860 6987 -423 459 329 C ATOM 740 N9 DG B 12 2.541 38.062 124.939 1.00 45.55 N ANISOU 740 N9 DG B 12 4687 6447 6172 -473 218 449 N ATOM 741 C8 DG B 12 2.562 38.142 126.311 1.00 43.40 C ANISOU 741 C8 DG B 12 4409 6200 5878 -468 -6 650 C ATOM 742 N7 DG B 12 1.886 39.155 126.773 1.00 41.43 N ANISOU 742 N7 DG B 12 4381 6032 5326 -535 -139 621 N ATOM 743 C5 DG B 12 1.398 39.788 125.637 1.00 40.88 C ANISOU 743 C5 DG B 12 4457 5950 5123 -569 -36 451 C ATOM 744 C6 DG B 12 0.609 40.957 125.503 1.00 39.57 C ANISOU 744 C6 DG B 12 4501 5790 4741 -631 -127 370 C ATOM 745 O6 DG B 12 0.187 41.704 126.389 1.00 39.43 O ANISOU 745 O6 DG B 12 4583 5783 4613 -655 -275 355 O ATOM 746 N1 DG B 12 0.355 41.256 124.166 1.00 40.24 N ANISOU 746 N1 DG B 12 4650 5868 4768 -697 -29 293 N ATOM 747 C2 DG B 12 0.800 40.523 123.097 1.00 40.61 C ANISOU 747 C2 DG B 12 4592 5955 4883 -728 174 233 C ATOM 748 N2 DG B 12 0.437 40.961 121.882 1.00 40.69 N ANISOU 748 N2 DG B 12 4693 6027 4738 -868 229 178 N ATOM 749 N3 DG B 12 1.533 39.426 123.209 1.00 41.19 N ANISOU 749 N3 DG B 12 4461 6008 5181 -651 312 221 N ATOM 750 C4 DG B 12 1.785 39.117 124.498 1.00 41.63 C ANISOU 750 C4 DG B 12 4436 6018 5363 -559 177 360 C TER 751 DG B 12 ATOM 752 O5' DC C 1 -3.582 48.825 121.692 1.00 44.74 O ANISOU 752 O5' DC C 1 5664 5032 6301 -752 -1065 373 O ATOM 753 C5' DC C 1 -2.841 48.925 120.453 1.00 44.76 C ANISOU 753 C5' DC C 1 5680 5121 6205 -918 -1137 639 C ATOM 754 C4' DC C 1 -2.688 47.577 119.780 1.00 42.68 C ANISOU 754 C4' DC C 1 5518 5106 5591 -996 -975 667 C ATOM 755 O4' DC C 1 -1.852 46.715 120.591 1.00 41.37 O ANISOU 755 O4' DC C 1 5412 5020 5285 -908 -809 489 O ATOM 756 C3' DC C 1 -3.983 46.812 119.517 1.00 43.45 C ANISOU 756 C3' DC C 1 5641 5267 5599 -982 -931 653 C ATOM 757 O3' DC C 1 -3.941 46.305 118.166 1.00 42.06 O ANISOU 757 O3' DC C 1 5503 5281 5194 -1191 -911 821 O ATOM 758 C2' DC C 1 -4.020 45.790 120.638 1.00 39.74 C ANISOU 758 C2' DC C 1 5233 4848 5017 -826 -755 410 C ATOM 759 C1' DC C 1 -2.547 45.519 120.903 1.00 39.85 C ANISOU 759 C1' DC C 1 5273 4917 4948 -837 -677 372 C ATOM 760 N1 DC C 1 -2.229 45.148 122.305 1.00 37.26 N ANISOU 760 N1 DC C 1 4964 4573 4618 -717 -619 200 N ATOM 761 C2 DC C 1 -1.506 43.975 122.548 1.00 35.38 C ANISOU 761 C2 DC C 1 4751 4429 4262 -710 -503 168 C ATOM 762 O2 DC C 1 -1.152 43.280 121.589 1.00 39.09 O ANISOU 762 O2 DC C 1 5216 4975 4659 -782 -410 218 O ATOM 763 N3 DC C 1 -1.229 43.618 123.824 1.00 35.46 N ANISOU 763 N3 DC C 1 4769 4445 4260 -654 -501 82 N ATOM 764 C4 DC C 1 -1.633 44.396 124.836 1.00 36.60 C ANISOU 764 C4 DC C 1 4915 4546 4443 -626 -568 -25 C ATOM 765 N4 DC C 1 -1.372 43.989 126.081 1.00 38.09 N ANISOU 765 N4 DC C 1 5121 4802 4547 -639 -570 -96 N ATOM 766 C5 DC C 1 -2.344 45.614 124.614 1.00 37.39 C ANISOU 766 C5 DC C 1 4978 4531 4697 -612 -639 -69 C ATOM 767 C6 DC C 1 -2.604 45.956 123.344 1.00 38.31 C ANISOU 767 C6 DC C 1 5069 4601 4886 -648 -684 74 C ATOM 768 P DG C 2 -4.975 45.306 117.603 1.00 45.54 P ANISOU 768 P DG C 2 5994 5856 5451 -1250 -842 821 P ATOM 769 OP1 DG C 2 -5.073 45.572 116.155 1.00 45.89 O ANISOU 769 OP1 DG C 2 6032 6047 5354 -1545 -952 1077 O ATOM 770 OP2 DG C 2 -6.278 45.315 118.388 1.00 42.07 O ANISOU 770 OP2 DG C 2 5517 5277 5190 -1076 -885 738 O ATOM 771 O5' DG C 2 -4.263 43.882 117.711 1.00 42.04 O ANISOU 771 O5' DG C 2 5629 5572 4773 -1228 -580 619 O ATOM 772 C5' DG C 2 -2.916 43.712 117.223 1.00 42.81 C ANISOU 772 C5' DG C 2 5723 5775 4765 -1346 -468 599 C ATOM 773 C4' DG C 2 -2.560 42.251 117.091 1.00 42.31 C ANISOU 773 C4' DG C 2 5681 5824 4567 -1350 -223 402 C ATOM 774 O4' DG C 2 -2.262 41.670 118.394 1.00 39.73 O ANISOU 774 O4' DG C 2 5342 5374 4381 -1119 -164 261 O ATOM 775 C3' DG C 2 -3.643 41.372 116.472 1.00 41.80 C ANISOU 775 C3' DG C 2 5664 5873 4343 -1434 -160 366 C ATOM 776 O3' DG C 2 -2.978 40.406 115.672 1.00 45.62 O ANISOU 776 O3' DG C 2 6135 6510 4686 -1592 68 208 O ATOM 777 C2' DG C 2 -4.343 40.753 117.666 1.00 39.59 C ANISOU 777 C2' DG C 2 5396 5465 4178 -1188 -151 263 C ATOM 778 C1' DG C 2 -3.276 40.717 118.762 1.00 38.96 C ANISOU 778 C1' DG C 2 5277 5275 4250 -1030 -116 180 C ATOM 779 N9 DG C 2 -3.689 41.045 120.129 1.00 38.22 N ANISOU 779 N9 DG C 2 5187 5063 4271 -849 -214 164 N ATOM 780 C8 DG C 2 -4.400 42.155 120.518 1.00 39.39 C ANISOU 780 C8 DG C 2 5331 5129 4506 -801 -360 216 C ATOM 781 N7 DG C 2 -4.474 42.292 121.815 1.00 35.98 N ANISOU 781 N7 DG C 2 4893 4632 4144 -680 -380 123 N ATOM 782 C5 DG C 2 -3.739 41.228 122.314 1.00 36.66 C ANISOU 782 C5 DG C 2 4985 4763 4181 -655 -287 73 C ATOM 783 C6 DG C 2 -3.461 40.860 123.654 1.00 34.72 C ANISOU 783 C6 DG C 2 4735 4516 3941 -596 -298 20 C ATOM 784 O6 DG C 2 -3.833 41.422 124.696 1.00 35.02 O ANISOU 784 O6 DG C 2 4781 4551 3973 -570 -353 -48 O ATOM 785 N1 DG C 2 -2.682 39.708 123.720 1.00 32.64 N ANISOU 785 N1 DG C 2 4435 4262 3702 -605 -237 47 N ATOM 786 C2 DG C 2 -2.201 39.016 122.629 1.00 35.36 C ANISOU 786 C2 DG C 2 4739 4604 4090 -649 -128 46 C ATOM 787 N2 DG C 2 -1.480 37.913 122.896 1.00 34.53 N ANISOU 787 N2 DG C 2 4550 4450 4119 -638 -77 46 N ATOM 788 N3 DG C 2 -2.465 39.346 121.365 1.00 35.43 N ANISOU 788 N3 DG C 2 4770 4661 4029 -731 -74 40 N ATOM 789 C4 DG C 2 -3.239 40.450 121.285 1.00 36.99 C ANISOU 789 C4 DG C 2 5015 4860 4178 -735 -181 89 C ATOM 790 P DG C 3 -3.819 39.449 114.687 1.00 47.77 P ANISOU 790 P DG C 3 6452 6962 4736 -1785 181 122 P ATOM 791 OP1 DG C 3 -2.922 39.036 113.640 1.00 49.99 O ANISOU 791 OP1 DG C 3 6698 7438 4858 -2048 400 -31 O ATOM 792 OP2 DG C 3 -5.140 40.068 114.379 1.00 46.49 O ANISOU 792 OP2 DG C 3 6343 6827 4494 -1858 -44 350 O ATOM 793 O5' DG C 3 -4.196 38.208 115.627 1.00 44.78 O ANISOU 793 O5' DG C 3 6061 6441 4509 -1541 287 -59 O ATOM 794 C5' DG C 3 -3.174 37.291 116.095 1.00 43.96 C ANISOU 794 C5' DG C 3 5866 6241 4593 -1432 473 -261 C ATOM 795 C4' DG C 3 -3.763 36.345 117.121 1.00 42.85 C ANISOU 795 C4' DG C 3 5715 5953 4611 -1218 462 -309 C ATOM 796 O4' DG C 3 -4.116 37.060 118.335 1.00 38.50 O ANISOU 796 O4' DG C 3 5198 5296 4131 -1031 267 -155 O ATOM 797 C3' DG C 3 -5.050 35.654 116.650 1.00 41.64 C ANISOU 797 C3' DG C 3 5622 5876 4321 -1286 481 -344 C ATOM 798 O3' DG C 3 -5.067 34.299 117.068 1.00 42.91 O ANISOU 798 O3' DG C 3 5715 5928 4658 -1191 596 -494 O ATOM 799 C2' DG C 3 -6.155 36.359 117.417 1.00 40.36 C ANISOU 799 C2' DG C 3 5527 5667 4139 -1155 267 -157 C ATOM 800 C1' DG C 3 -5.419 36.641 118.726 1.00 38.08 C ANISOU 800 C1' DG C 3 5194 5237 4036 -961 210 -130 C ATOM 801 N9 DG C 3 -5.948 37.638 119.636 1.00 37.26 N ANISOU 801 N9 DG C 3 5120 5080 3956 -848 43 -18 N ATOM 802 C8 DG C 3 -6.679 38.772 119.366 1.00 38.10 C ANISOU 802 C8 DG C 3 5251 5194 4029 -879 -90 89 C ATOM 803 N7 DG C 3 -6.981 39.449 120.445 1.00 36.37 N ANISOU 803 N7 DG C 3 5017 4889 3912 -752 -181 95 N ATOM 804 C5 DG C 3 -6.327 38.776 121.470 1.00 33.75 C ANISOU 804 C5 DG C 3 4673 4535 3613 -666 -123 21 C ATOM 805 C6 DG C 3 -6.280 39.041 122.873 1.00 33.94 C ANISOU 805 C6 DG C 3 4687 4529 3678 -579 -171 -15 C ATOM 806 O6 DG C 3 -6.749 39.995 123.493 1.00 34.62 O ANISOU 806 O6 DG C 3 4765 4586 3803 -543 -236 -54 O ATOM 807 N1 DG C 3 -5.608 38.041 123.558 1.00 34.14 N ANISOU 807 N1 DG C 3 4692 4562 3717 -566 -137 -14 N ATOM 808 C2 DG C 3 -4.979 36.974 122.974 1.00 34.94 C ANISOU 808 C2 DG C 3 4751 4639 3884 -593 -54 -9 C ATOM 809 N2 DG C 3 -4.362 36.132 123.803 1.00 34.28 N ANISOU 809 N2 DG C 3 4605 4514 3904 -577 -75 33 N ATOM 810 N3 DG C 3 -5.040 36.696 121.679 1.00 34.86 N ANISOU 810 N3 DG C 3 4742 4649 3853 -661 39 -50 N ATOM 811 C4 DG C 3 -5.735 37.628 120.997 1.00 34.35 C ANISOU 811 C4 DG C 3 4731 4634 3685 -710 -5 -21 C ATOM 812 P DA C 4 -5.403 33.145 116.012 1.00 47.39 P ANISOU 812 P DA C 4 6259 6576 5168 -1367 797 -722 P ATOM 813 OP1 DA C 4 -4.449 33.260 114.939 1.00 46.05 O ANISOU 813 OP1 DA C 4 6039 6532 4923 -1587 987 -898 O ATOM 814 OP2 DA C 4 -6.855 33.196 115.672 1.00 48.60 O ANISOU 814 OP2 DA C 4 6527 6841 5098 -1439 691 -624 O ATOM 815 O5' DA C 4 -5.125 31.827 116.875 1.00 46.91 O ANISOU 815 O5' DA C 4 6066 6284 5471 -1188 862 -829 O ATOM 816 C5' DA C 4 -3.809 31.589 117.422 1.00 44.81 C ANISOU 816 C5' DA C 4 5644 5845 5536 -1087 914 -875 C ATOM 817 C4' DA C 4 -3.920 31.023 118.820 1.00 44.15 C ANISOU 817 C4' DA C 4 5498 5567 5709 -886 755 -712 C ATOM 818 O4' DA C 4 -4.481 32.001 119.734 1.00 41.01 O ANISOU 818 O4' DA C 4 5232 5240 5109 -798 538 -470 O ATOM 819 C3' DA C 4 -4.806 29.780 118.947 1.00 45.93 C ANISOU 819 C3' DA C 4 5689 5708 6054 -864 768 -757 C ATOM 820 O3' DA C 4 -4.184 29.013 119.969 1.00 47.42 O ANISOU 820 O3' DA C 4 5709 5666 6642 -745 681 -657 O ATOM 821 C2' DA C 4 -6.149 30.349 119.387 1.00 43.95 C ANISOU 821 C2' DA C 4 5615 5596 5485 -831 602 -570 C ATOM 822 C1' DA C 4 -5.725 31.526 120.277 1.00 41.01 C ANISOU 822 C1' DA C 4 5292 5253 5035 -748 447 -385 C ATOM 823 N9 DA C 4 -6.645 32.666 120.323 1.00 36.25 N ANISOU 823 N9 DA C 4 4835 4795 4143 -751 342 -283 N ATOM 824 C8 DA C 4 -7.284 33.262 119.275 1.00 36.33 C ANISOU 824 C8 DA C 4 4931 4933 3937 -864 363 -308 C ATOM 825 N7 DA C 4 -7.980 34.318 119.612 1.00 35.34 N ANISOU 825 N7 DA C 4 4875 4858 3694 -827 228 -184 N ATOM 826 C5 DA C 4 -7.756 34.446 120.970 1.00 35.83 C ANISOU 826 C5 DA C 4 4911 4852 3848 -697 150 -123 C ATOM 827 C6 DA C 4 -8.198 35.387 121.918 1.00 35.36 C ANISOU 827 C6 DA C 4 4879 4806 3751 -625 39 -58 C ATOM 828 N6 DA C 4 -8.997 36.415 121.625 1.00 34.73 N ANISOU 828 N6 DA C 4 4828 4752 3616 -634 -25 -30 N ATOM 829 N1 DA C 4 -7.806 35.218 123.195 1.00 34.37 N ANISOU 829 N1 DA C 4 4725 4662 3672 -571 -6 -29 N ATOM 830 C2 DA C 4 -7.008 34.188 123.490 1.00 34.90 C ANISOU 830 C2 DA C 4 4725 4667 3867 -574 11 -1 C ATOM 831 N3 DA C 4 -6.511 33.253 122.685 1.00 36.08 N ANISOU 831 N3 DA C 4 4811 4739 4157 -601 107 -56 N ATOM 832 C4 DA C 4 -6.919 33.447 121.420 1.00 35.96 C ANISOU 832 C4 DA C 4 4843 4777 4043 -666 196 -149 C ATOM 833 P DG C 5 -4.721 27.541 120.349 1.00 54.97 P ANISOU 833 P DG C 5 6541 6435 7908 -708 653 -649 P ATOM 834 OP1 DG C 5 -3.538 26.814 120.871 1.00 54.42 O ANISOU 834 OP1 DG C 5 6211 6083 8383 -648 622 -613 O ATOM 835 OP2 DG C 5 -5.603 27.036 119.262 1.00 49.02 O ANISOU 835 OP2 DG C 5 5847 5762 7014 -815 819 -883 O ATOM 836 O5' DG C 5 -5.721 27.810 121.571 1.00 47.97 O ANISOU 836 O5' DG C 5 5786 5647 6791 -646 406 -339 O ATOM 837 C5' DG C 5 -5.136 28.304 122.802 1.00 45.36 C ANISOU 837 C5' DG C 5 5436 5308 6489 -597 212 -90 C ATOM 838 C4' DG C 5 -6.211 28.586 123.825 1.00 41.52 C ANISOU 838 C4' DG C 5 5080 4982 5712 -599 47 112 C ATOM 839 O4' DG C 5 -6.916 29.791 123.440 1.00 39.71 O ANISOU 839 O4' DG C 5 5036 4956 5095 -600 95 34 O ATOM 840 C3' DG C 5 -7.273 27.488 123.969 1.00 42.00 C ANISOU 840 C3' DG C 5 5116 5012 5827 -619 19 160 C ATOM 841 O3' DG C 5 -7.371 27.125 125.366 1.00 40.96 O ANISOU 841 O3' DG C 5 4936 4897 5727 -659 -193 447 O ATOM 842 C2' DG C 5 -8.503 28.101 123.318 1.00 38.97 C ANISOU 842 C2' DG C 5 4910 4817 5077 -629 108 41 C ATOM 843 C1' DG C 5 -8.306 29.569 123.611 1.00 38.39 C ANISOU 843 C1' DG C 5 4948 4891 4746 -611 72 65 C ATOM 844 N9 DG C 5 -9.019 30.502 122.742 1.00 37.09 N ANISOU 844 N9 DG C 5 4908 4851 4331 -623 144 -45 N ATOM 845 C8 DG C 5 -9.088 30.465 121.368 1.00 36.09 C ANISOU 845 C8 DG C 5 4806 4735 4170 -686 267 -196 C ATOM 846 N7 DG C 5 -9.739 31.478 120.862 1.00 34.76 N ANISOU 846 N7 DG C 5 4737 4688 3781 -719 248 -192 N ATOM 847 C5 DG C 5 -10.085 32.251 121.963 1.00 34.00 C ANISOU 847 C5 DG C 5 4666 4630 3619 -643 137 -84 C ATOM 848 C6 DG C 5 -10.872 33.436 122.046 1.00 33.41 C ANISOU 848 C6 DG C 5 4644 4628 3422 -626 74 -54 C ATOM 849 O6 DG C 5 -11.318 34.135 121.118 1.00 33.69 O ANISOU 849 O6 DG C 5 4711 4695 3393 -679 56 -50 O ATOM 850 N1 DG C 5 -10.945 33.903 123.354 1.00 32.90 N ANISOU 850 N1 DG C 5 4566 4588 3346 -569 17 -25 N ATOM 851 C2 DG C 5 -10.492 33.223 124.463 1.00 33.57 C ANISOU 851 C2 DG C 5 4615 4679 3458 -570 -9 27 C ATOM 852 N2 DG C 5 -10.736 33.801 125.647 1.00 34.31 N ANISOU 852 N2 DG C 5 4711 4864 3461 -579 -51 28 N ATOM 853 N3 DG C 5 -9.805 32.091 124.407 1.00 33.05 N ANISOU 853 N3 DG C 5 4494 4533 3530 -587 -3 75 N ATOM 854 C4 DG C 5 -9.643 31.664 123.132 1.00 34.86 C ANISOU 854 C4 DG C 5 4715 4693 3835 -604 85 -8 C ATOM 855 P DT C 6 -8.369 26.035 125.919 1.00 45.06 P ANISOU 855 P DT C 6 5412 5410 6297 -715 -295 607 P ATOM 856 OP1 DT C 6 -7.685 25.308 127.074 1.00 49.34 O ANISOU 856 OP1 DT C 6 5784 5841 7119 -799 -535 933 O ATOM 857 OP2 DT C 6 -8.929 25.180 124.853 1.00 45.88 O ANISOU 857 OP2 DT C 6 5478 5386 6568 -688 -154 418 O ATOM 858 O5' DT C 6 -9.585 26.905 126.489 1.00 42.99 O ANISOU 858 O5' DT C 6 5337 5453 5541 -753 -305 632 O ATOM 859 C5' DT C 6 -9.277 27.885 127.504 1.00 42.93 C ANISOU 859 C5' DT C 6 5394 5626 5290 -810 -393 728 C ATOM 860 C4' DT C 6 -10.489 28.652 127.973 1.00 41.79 C ANISOU 860 C4' DT C 6 5379 5737 4762 -847 -349 665 C ATOM 861 O4' DT C 6 -10.851 29.576 126.931 1.00 38.65 O ANISOU 861 O4' DT C 6 5073 5340 4272 -738 -200 433 O ATOM 862 C3' DT C 6 -11.767 27.890 128.349 1.00 42.21 C ANISOU 862 C3' DT C 6 5425 5890 4722 -918 -364 745 C ATOM 863 O3' DT C 6 -12.184 28.427 129.618 1.00 42.73 O ANISOU 863 O3' DT C 6 5530 6223 4482 -1062 -409 807 O ATOM 864 C2' DT C 6 -12.740 28.267 127.253 1.00 38.54 C ANISOU 864 C2' DT C 6 5035 5419 4187 -812 -209 530 C ATOM 865 C1' DT C 6 -12.252 29.646 126.866 1.00 37.40 C ANISOU 865 C1' DT C 6 4963 5294 3952 -741 -142 373 C ATOM 866 N1 DT C 6 -12.600 30.072 125.494 1.00 36.04 N ANISOU 866 N1 DT C 6 4840 5054 3799 -660 -40 216 N ATOM 867 C2 DT C 6 -13.240 31.268 125.281 1.00 35.60 C ANISOU 867 C2 DT C 6 4837 5074 3613 -626 -2 116 C ATOM 868 O2 DT C 6 -13.522 32.047 126.177 1.00 34.15 O ANISOU 868 O2 DT C 6 4655 4997 3322 -639 -8 85 O ATOM 869 N3 DT C 6 -13.477 31.560 123.960 1.00 34.02 N ANISOU 869 N3 DT C 6 4670 4818 3437 -605 39 47 N ATOM 870 C4 DT C 6 -13.152 30.789 122.864 1.00 35.59 C ANISOU 870 C4 DT C 6 4869 4937 3714 -639 85 13 C ATOM 871 O4 DT C 6 -13.451 31.177 121.733 1.00 34.43 O ANISOU 871 O4 DT C 6 4763 4804 3513 -682 111 -37 O ATOM 872 C5 DT C 6 -12.503 29.539 123.164 1.00 35.06 C ANISOU 872 C5 DT C 6 4733 4773 3813 -651 90 45 C ATOM 873 C7 DT C 6 -12.115 28.629 122.049 1.00 36.95 C ANISOU 873 C7 DT C 6 4934 4901 4202 -696 183 -70 C ATOM 874 C6 DT C 6 -12.253 29.252 124.446 1.00 38.16 C ANISOU 874 C6 DT C 6 5078 5180 4239 -651 6 172 C ATOM 875 P DG C 7 -13.594 28.075 130.314 1.00 42.90 P ANISOU 875 P DG C 7 5556 6467 4278 -1187 -388 848 P ATOM 876 OP1 DG C 7 -13.303 27.968 131.768 1.00 44.39 O ANISOU 876 OP1 DG C 7 5717 6890 4259 -1439 -523 1048 O ATOM 877 OP2 DG C 7 -14.247 26.902 129.721 1.00 41.02 O ANISOU 877 OP2 DG C 7 5264 6095 4225 -1151 -401 928 O ATOM 878 O5' DG C 7 -14.473 29.393 130.116 1.00 41.66 O ANISOU 878 O5' DG C 7 5475 6436 3918 -1112 -205 552 O ATOM 879 C5' DG C 7 -13.929 30.691 130.475 1.00 44.42 C ANISOU 879 C5' DG C 7 5865 6858 4151 -1111 -160 394 C ATOM 880 C4' DG C 7 -15.019 31.735 130.583 1.00 44.36 C ANISOU 880 C4' DG C 7 5862 6967 4025 -1085 0 132 C ATOM 881 O4' DG C 7 -15.429 32.203 129.275 1.00 43.46 O ANISOU 881 O4' DG C 7 5756 6657 4099 -889 61 17 O ATOM 882 C3' DG C 7 -16.307 31.281 131.254 1.00 44.71 C ANISOU 882 C3' DG C 7 5858 7215 3915 -1212 71 117 C ATOM 883 O3' DG C 7 -16.894 32.427 131.877 1.00 45.76 O ANISOU 883 O3' DG C 7 5955 7502 3928 -1263 229 -168 O ATOM 884 C2' DG C 7 -17.147 30.784 130.082 1.00 43.46 C ANISOU 884 C2' DG C 7 5685 6881 3946 -1056 94 134 C ATOM 885 C1' DG C 7 -16.745 31.707 128.951 1.00 40.86 C ANISOU 885 C1' DG C 7 5388 6343 3792 -872 114 11 C ATOM 886 N9 DG C 7 -16.658 31.060 127.639 1.00 37.34 N ANISOU 886 N9 DG C 7 4969 5706 3511 -771 67 100 N ATOM 887 C8 DG C 7 -16.019 29.877 127.358 1.00 36.94 C ANISOU 887 C8 DG C 7 4924 5562 3546 -791 -8 254 C ATOM 888 N7 DG C 7 -16.015 29.586 126.083 1.00 35.67 N ANISOU 888 N7 DG C 7 4784 5253 3515 -720 4 227 N ATOM 889 C5 DG C 7 -16.668 30.655 125.487 1.00 34.31 C ANISOU 889 C5 DG C 7 4629 5086 3318 -663 50 112 C ATOM 890 C6 DG C 7 -17.008 30.872 124.136 1.00 35.28 C ANISOU 890 C6 DG C 7 4779 5127 3499 -637 52 79 C ATOM 891 O6 DG C 7 -16.695 30.192 123.152 1.00 32.63 O ANISOU 891 O6 DG C 7 4472 4717 3206 -667 55 85 O ATOM 892 N1 DG C 7 -17.688 32.076 123.965 1.00 33.18 N ANISOU 892 N1 DG C 7 4483 4867 3256 -601 48 25 N ATOM 893 C2 DG C 7 -18.020 32.943 124.973 1.00 33.81 C ANISOU 893 C2 DG C 7 4500 5004 3341 -574 84 -61 C ATOM 894 N2 DG C 7 -18.669 34.054 124.611 1.00 33.10 N ANISOU 894 N2 DG C 7 4338 4848 3390 -529 69 -118 N ATOM 895 N3 DG C 7 -17.711 32.745 126.248 1.00 34.49 N ANISOU 895 N3 DG C 7 4578 5207 3320 -618 126 -93 N ATOM 896 C4 DG C 7 -17.059 31.580 126.432 1.00 35.68 C ANISOU 896 C4 DG C 7 4769 5372 3412 -671 87 29 C ATOM 897 P DT C 8 -18.225 32.274 132.775 1.00 52.14 P ANISOU 897 P DT C 8 6681 8582 4547 -1438 375 -292 P ATOM 898 OP1 DT C 8 -18.318 33.423 133.653 1.00 51.93 O ANISOU 898 OP1 DT C 8 6609 8734 4388 -1556 539 -617 O ATOM 899 OP2 DT C 8 -18.319 30.895 133.304 1.00 50.48 O ANISOU 899 OP2 DT C 8 6475 8525 4178 -1626 258 9 O ATOM 900 O5' DT C 8 -19.439 32.380 131.715 1.00 50.11 O ANISOU 900 O5' DT C 8 6354 8135 4548 -1230 458 -386 O ATOM 901 C5' DT C 8 -19.741 33.596 130.976 1.00 49.61 C ANISOU 901 C5' DT C 8 6233 7869 4746 -1040 533 -611 C ATOM 902 C4' DT C 8 -20.834 33.371 129.941 1.00 49.98 C ANISOU 902 C4' DT C 8 6216 7752 5021 -901 527 -565 C ATOM 903 O4' DT C 8 -20.344 32.711 128.729 1.00 46.22 O ANISOU 903 O4' DT C 8 5839 7090 4631 -797 370 -331 O ATOM 904 C3' DT C 8 -22.042 32.543 130.398 1.00 51.25 C ANISOU 904 C3' DT C 8 6299 8078 5096 -1006 602 -539 C ATOM 905 O3' DT C 8 -23.274 33.150 130.001 1.00 55.37 O ANISOU 905 O3' DT C 8 6665 8499 5873 -912 698 -699 O ATOM 906 C2' DT C 8 -21.917 31.248 129.620 1.00 49.77 C ANISOU 906 C2' DT C 8 6202 7799 4908 -977 446 -240 C ATOM 907 C1' DT C 8 -21.346 31.803 128.314 1.00 45.41 C ANISOU 907 C1' DT C 8 5706 6985 4561 -803 355 -220 C ATOM 908 N1 DT C 8 -20.738 30.837 127.388 1.00 43.44 N ANISOU 908 N1 DT C 8 5558 6613 4333 -772 229 -20 N ATOM 909 C2 DT C 8 -20.838 31.101 126.033 1.00 39.75 C ANISOU 909 C2 DT C 8 5114 5974 4015 -681 171 0 C ATOM 910 O2 DT C 8 -21.407 32.085 125.577 1.00 39.10 O ANISOU 910 O2 DT C 8 4964 5818 4071 -622 175 -74 O ATOM 911 N3 DT C 8 -20.253 30.163 125.228 1.00 37.91 N ANISOU 911 N3 DT C 8 4963 5657 3784 -693 103 112 N ATOM 912 C4 DT C 8 -19.580 29.026 125.619 1.00 38.92 C ANISOU 912 C4 DT C 8 5120 5791 3877 -748 73 210 C ATOM 913 O4 DT C 8 -19.102 28.277 124.766 1.00 38.76 O ANISOU 913 O4 DT C 8 5135 5652 3937 -749 41 246 O ATOM 914 C5 DT C 8 -19.486 28.823 127.056 1.00 41.37 C ANISOU 914 C5 DT C 8 5393 6256 4069 -835 81 258 C ATOM 915 C7 DT C 8 -18.791 27.605 127.575 1.00 41.15 C ANISOU 915 C7 DT C 8 5356 6216 4060 -924 -10 441 C ATOM 916 C6 DT C 8 -20.077 29.718 127.855 1.00 38.75 C ANISOU 916 C6 DT C 8 5011 6070 3639 -862 165 136 C ATOM 917 P DA C 9 -24.257 33.752 131.117 1.00 61.74 P ANISOU 917 P DA C 9 7281 9495 6682 -1027 946 -1030 P ATOM 918 OP1 DA C 9 -23.445 34.649 131.952 1.00 58.36 O ANISOU 918 OP1 DA C 9 6862 9165 6147 -1110 1043 -1272 O ATOM 919 OP2 DA C 9 -24.991 32.605 131.683 1.00 60.34 O ANISOU 919 OP2 DA C 9 7088 9555 6280 -1193 990 -917 O ATOM 920 O5' DA C 9 -25.183 34.719 130.257 1.00 59.24 O ANISOU 920 O5' DA C 9 6772 8889 6847 -834 969 -1166 O ATOM 921 C5' DA C 9 -24.589 35.747 129.435 1.00 56.66 C ANISOU 921 C5' DA C 9 6442 8281 6802 -674 855 -1171 C ATOM 922 C4' DA C 9 -25.462 36.017 128.225 1.00 56.88 C ANISOU 922 C4' DA C 9 6345 8038 7228 -535 726 -1036 C ATOM 923 O4' DA C 9 -25.136 35.104 127.156 1.00 54.06 O ANISOU 923 O4' DA C 9 6172 7640 6728 -520 519 -693 O ATOM 924 C3' DA C 9 -26.969 35.871 128.431 1.00 58.86 C ANISOU 924 C3' DA C 9 6369 8299 7694 -546 841 -1134 C ATOM 925 O3' DA C 9 -27.566 36.840 127.573 1.00 59.70 O ANISOU 925 O3' DA C 9 6268 8083 8329 -414 732 -1116 O ATOM 926 C2' DA C 9 -27.241 34.437 128.008 1.00 55.25 C ANISOU 926 C2' DA C 9 6058 7959 6972 -604 734 -837 C ATOM 927 C1' DA C 9 -26.232 34.221 126.891 1.00 51.76 C ANISOU 927 C1' DA C 9 5829 7391 6444 -551 504 -570 C ATOM 928 N9 DA C 9 -25.677 32.876 126.793 1.00 47.62 N ANISOU 928 N9 DA C 9 5514 7001 5576 -628 438 -370 N ATOM 929 C8 DA C 9 -25.355 32.065 127.856 1.00 47.06 C ANISOU 929 C8 DA C 9 5514 7161 5205 -748 528 -384 C ATOM 930 N7 DA C 9 -24.785 30.942 127.507 1.00 45.68 N ANISOU 930 N7 DA C 9 5492 7001 4863 -787 415 -172 N ATOM 931 C5 DA C 9 -24.712 31.020 126.121 1.00 42.41 C ANISOU 931 C5 DA C 9 5127 6388 4596 -701 281 -60 C ATOM 932 C6 DA C 9 -24.211 30.136 125.160 1.00 39.75 C ANISOU 932 C6 DA C 9 4921 5976 4204 -715 163 100 C ATOM 933 N6 DA C 9 -23.658 28.961 125.469 1.00 39.28 N ANISOU 933 N6 DA C 9 4943 5969 4010 -780 147 192 N ATOM 934 N1 DA C 9 -24.302 30.498 123.857 1.00 38.51 N ANISOU 934 N1 DA C 9 4786 5685 4158 -690 59 161 N ATOM 935 C2 DA C 9 -24.843 31.689 123.561 1.00 39.79 C ANISOU 935 C2 DA C 9 4832 5759 4524 -639 28 125 C ATOM 936 N3 DA C 9 -25.332 32.620 124.386 1.00 42.78 N ANISOU 936 N3 DA C 9 5053 6134 5068 -583 121 -24 N ATOM 937 C4 DA C 9 -25.246 32.211 125.667 1.00 42.49 C ANISOU 937 C4 DA C 9 5012 6265 4866 -621 271 -145 C ATOM 938 P DG C 10 -29.137 37.057 127.527 1.00 63.81 P ANISOU 938 P DG C 10 6467 8479 9296 -378 800 -1203 P ATOM 939 OP1 DG C 10 -29.377 38.452 127.101 1.00 68.20 O ANISOU 939 OP1 DG C 10 6757 8680 10475 -257 727 -1295 O ATOM 940 OP2 DG C 10 -29.770 36.493 128.727 1.00 61.91 O ANISOU 940 OP2 DG C 10 6150 8523 8848 -499 1085 -1457 O ATOM 941 O5' DG C 10 -29.617 36.116 126.336 1.00 61.30 O ANISOU 941 O5' DG C 10 6250 8118 8920 -383 549 -786 O ATOM 942 C5' DG C 10 -29.174 36.376 125.010 1.00 58.44 C ANISOU 942 C5' DG C 10 5985 7564 8656 -349 254 -476 C ATOM 943 C4' DG C 10 -29.673 35.265 124.119 1.00 55.70 C ANISOU 943 C4' DG C 10 5752 7275 8133 -423 88 -165 C ATOM 944 O4' DG C 10 -28.914 34.061 124.378 1.00 51.33 O ANISOU 944 O4' DG C 10 5483 6962 7057 -496 145 -127 O ATOM 945 C3' DG C 10 -31.150 34.899 124.310 1.00 56.92 C ANISOU 945 C3' DG C 10 5683 7428 8516 -435 144 -176 C ATOM 946 O3' DG C 10 -31.659 34.814 122.982 1.00 59.41 O ANISOU 946 O3' DG C 10 5977 7597 8997 -477 -146 161 O ATOM 947 C2' DG C 10 -31.098 33.565 125.026 1.00 54.48 C ANISOU 947 C2' DG C 10 5547 7412 7741 -521 297 -214 C ATOM 948 C1' DG C 10 -29.816 32.983 124.463 1.00 52.13 C ANISOU 948 C1' DG C 10 5570 7178 7057 -561 172 -49 C ATOM 949 N9 DG C 10 -29.180 31.937 125.251 1.00 50.37 N ANISOU 949 N9 DG C 10 5532 7185 6419 -632 289 -88 N ATOM 950 C8 DG C 10 -29.164 31.791 126.617 1.00 51.54 C ANISOU 950 C8 DG C 10 5640 7534 6406 -687 503 -285 C ATOM 951 N7 DG C 10 -28.497 30.738 127.009 1.00 50.21 N ANISOU 951 N7 DG C 10 5653 7529 5894 -777 499 -188 N ATOM 952 C5 DG C 10 -28.083 30.136 125.829 1.00 46.86 C ANISOU 952 C5 DG C 10 5381 6981 5439 -756 309 28 C ATOM 953 C6 DG C 10 -27.369 28.935 125.615 1.00 45.29 C ANISOU 953 C6 DG C 10 5360 6820 5026 -817 231 179 C ATOM 954 O6 DG C 10 -26.906 28.157 126.455 1.00 46.25 O ANISOU 954 O6 DG C 10 5538 7074 4959 -898 269 215 O ATOM 955 N1 DG C 10 -27.163 28.696 124.260 1.00 40.11 N ANISOU 955 N1 DG C 10 4798 6021 4419 -805 86 296 N ATOM 956 C2 DG C 10 -27.619 29.489 123.241 1.00 41.51 C ANISOU 956 C2 DG C 10 4922 6074 4776 -776 -13 333 C ATOM 957 N2 DG C 10 -27.361 29.067 121.997 1.00 41.99 N ANISOU 957 N2 DG C 10 5097 6073 4782 -843 -143 446 N ATOM 958 N3 DG C 10 -28.312 30.597 123.426 1.00 44.59 N ANISOU 958 N3 DG C 10 5133 6402 5408 -714 6 265 N ATOM 959 C4 DG C 10 -28.497 30.863 124.737 1.00 46.88 C ANISOU 959 C4 DG C 10 5315 6795 5700 -690 187 85 C ATOM 960 P DG C 11 -33.228 34.715 122.615 1.00 62.36 P ANISOU 960 P DG C 11 6076 7851 9765 -495 -243 296 P ATOM 961 OP1 DG C 11 -33.633 36.023 122.062 1.00 66.08 O ANISOU 961 OP1 DG C 11 6256 7999 10850 -441 -432 395 O ATOM 962 OP2 DG C 11 -34.009 34.139 123.733 1.00 61.00 O ANISOU 962 OP2 DG C 11 5781 7834 9559 -487 33 59 O ATOM 963 O5' DG C 11 -33.176 33.593 121.474 1.00 59.13 O ANISOU 963 O5' DG C 11 5924 7554 8988 -645 -471 632 O ATOM 964 C5' DG C 11 -32.073 33.558 120.522 1.00 53.50 C ANISOU 964 C5' DG C 11 5474 6870 7980 -733 -645 802 C ATOM 965 C4' DG C 11 -31.997 32.230 119.800 1.00 50.05 C ANISOU 965 C4' DG C 11 5283 6602 7131 -887 -724 955 C ATOM 966 O4' DG C 11 -31.267 31.253 120.575 1.00 47.47 O ANISOU 966 O4' DG C 11 5155 6450 6428 -859 -508 771 O ATOM 967 C3' DG C 11 -33.335 31.581 119.479 1.00 52.16 C ANISOU 967 C3' DG C 11 5428 6871 7517 -968 -819 1106 C ATOM 968 O3' DG C 11 -33.214 31.011 118.182 1.00 52.10 O ANISOU 968 O3' DG C 11 5600 6930 7265 -1177 -1038 1335 O ATOM 969 C2' DG C 11 -33.493 30.544 120.576 1.00 49.75 C ANISOU 969 C2' DG C 11 5170 6722 7008 -915 -565 911 C ATOM 970 C1' DG C 11 -32.071 30.110 120.833 1.00 46.70 C ANISOU 970 C1' DG C 11 5052 6451 6238 -908 -454 790 C ATOM 971 N9 DG C 11 -31.804 29.685 122.209 1.00 46.92 N ANISOU 971 N9 DG C 11 5092 6609 6126 -838 -209 585 N ATOM 972 C8 DG C 11 -32.146 30.359 123.357 1.00 47.06 C ANISOU 972 C8 DG C 11 4921 6648 6312 -753 -21 384 C ATOM 973 N7 DG C 11 -31.742 29.758 124.442 1.00 45.00 N ANISOU 973 N7 DG C 11 4733 6569 5794 -778 156 258 N ATOM 974 C5 DG C 11 -31.063 28.639 123.983 1.00 43.33 C ANISOU 974 C5 DG C 11 4753 6406 5304 -847 64 399 C ATOM 975 C6 DG C 11 -30.424 27.594 124.700 1.00 42.02 C ANISOU 975 C6 DG C 11 4719 6381 4863 -911 131 406 C ATOM 976 O6 DG C 11 -30.323 27.450 125.915 1.00 42.83 O ANISOU 976 O6 DG C 11 4786 6647 4839 -954 272 321 O ATOM 977 N1 DG C 11 -29.873 26.649 123.845 1.00 40.53 N ANISOU 977 N1 DG C 11 4700 6132 4567 -959 6 533 N ATOM 978 C2 DG C 11 -29.965 26.678 122.478 1.00 41.76 C ANISOU 978 C2 DG C 11 4914 6171 4781 -986 -138 615 C ATOM 979 N2 DG C 11 -29.373 25.668 121.824 1.00 41.91 N ANISOU 979 N2 DG C 11 5082 6159 4680 -1062 -196 654 N ATOM 980 N3 DG C 11 -30.559 27.643 121.798 1.00 41.13 N ANISOU 980 N3 DG C 11 4736 6009 4881 -969 -227 654 N ATOM 981 C4 DG C 11 -31.081 28.585 122.608 1.00 42.63 C ANISOU 981 C4 DG C 11 4739 6196 5263 -881 -131 558 C ATOM 982 P DC C 12 -34.482 30.605 117.384 1.00 56.34 P ANISOU 982 P DC C 12 6027 7449 7930 -1337 -1260 1589 P ATOM 983 OP1 DC C 12 -34.112 30.561 115.964 1.00 64.46 O ANISOU 983 OP1 DC C 12 7220 8547 8722 -1601 -1514 1818 O ATOM 984 OP2 DC C 12 -35.641 31.399 117.828 1.00 60.36 O ANISOU 984 OP2 DC C 12 6175 7771 8988 -1226 -1300 1642 O ATOM 985 O5' DC C 12 -34.643 29.065 117.706 1.00 58.84 O ANISOU 985 O5' DC C 12 6499 7926 7930 -1375 -1109 1479 O ATOM 986 C5' DC C 12 -33.616 28.215 117.162 1.00 55.30 C ANISOU 986 C5' DC C 12 6347 7608 7055 -1498 -1079 1413 C ATOM 987 C4' DC C 12 -33.598 26.924 117.927 1.00 52.90 C ANISOU 987 C4' DC C 12 6126 7384 6587 -1448 -887 1258 C ATOM 988 O4' DC C 12 -33.342 27.230 119.296 1.00 49.54 O ANISOU 988 O4' DC C 12 5618 6956 6247 -1247 -675 1093 O ATOM 989 C3' DC C 12 -34.925 26.201 117.966 1.00 54.67 C ANISOU 989 C3' DC C 12 6229 7617 6925 -1508 -942 1363 C ATOM 990 O3' DC C 12 -35.085 25.363 116.832 1.00 57.89 O ANISOU 990 O3' DC C 12 6772 8078 7143 -1738 -1091 1457 O ATOM 991 C2' DC C 12 -34.845 25.428 119.276 1.00 51.84 C ANISOU 991 C2' DC C 12 5863 7318 6513 -1385 -712 1208 C ATOM 992 C1' DC C 12 -33.666 26.058 119.992 1.00 48.45 C ANISOU 992 C1' DC C 12 5496 6897 6014 -1250 -561 1044 C ATOM 993 N1 DC C 12 -33.880 26.417 121.392 1.00 45.71 N ANISOU 993 N1 DC C 12 5001 6598 5767 -1119 -368 919 N ATOM 994 C2 DC C 12 -33.215 25.663 122.356 1.00 43.44 C ANISOU 994 C2 DC C 12 4808 6420 5274 -1108 -221 828 C ATOM 995 O2 DC C 12 -32.525 24.705 121.987 1.00 42.19 O ANISOU 995 O2 DC C 12 4824 6259 4948 -1172 -264 858 O ATOM 996 N3 DC C 12 -33.329 25.999 123.658 1.00 41.84 N ANISOU 996 N3 DC C 12 4489 6325 5081 -1057 -40 705 N ATOM 997 C4 DC C 12 -34.102 27.024 124.017 1.00 45.06 C ANISOU 997 C4 DC C 12 4675 6712 5734 -994 39 609 C ATOM 998 N4 DC C 12 -34.215 27.297 125.327 1.00 44.01 N ANISOU 998 N4 DC C 12 4424 6727 5568 -992 260 428 N ATOM 999 C5 DC C 12 -34.796 27.819 123.050 1.00 45.20 C ANISOU 999 C5 DC C 12 4556 6554 6063 -961 -110 694 C ATOM 1000 C6 DC C 12 -34.651 27.485 121.759 1.00 45.36 C ANISOU 1000 C6 DC C 12 4714 6494 6027 -1037 -333 881 C TER 1001 DC C 12 ATOM 1002 N ARG D 149 -3.280 54.987 138.831 1.00 90.13 N ANISOU 1002 N ARG D 149 13277 11724 9245 -2075 -769 -2204 N ATOM 1003 CA ARG D 149 -3.086 54.080 140.010 1.00 89.49 C ANISOU 1003 CA ARG D 149 13159 11982 8858 -2140 -945 -2183 C ATOM 1004 C ARG D 149 -3.951 54.457 141.217 1.00 89.96 C ANISOU 1004 C ARG D 149 13739 11904 8537 -2023 -739 -2409 C ATOM 1005 O ARG D 149 -3.474 55.088 142.157 1.00 93.94 O ANISOU 1005 O ARG D 149 14675 12320 8696 -2330 -880 -2633 O ATOM 1006 CB ARG D 149 -1.606 54.017 140.408 1.00 93.42 C ANISOU 1006 CB ARG D 149 13535 12716 9244 -2607 -1376 -2156 C ATOM 1007 CG ARG D 149 -0.719 53.479 139.296 1.00 92.91 C ANISOU 1007 CG ARG D 149 12910 12845 9544 -2660 -1532 -1873 C ATOM 1008 CD ARG D 149 0.621 52.980 139.830 1.00 96.57 C ANISOU 1008 CD ARG D 149 13087 13705 9899 -2995 -1940 -1721 C ATOM 1009 NE ARG D 149 1.460 52.435 138.753 1.00 95.83 N ANISOU 1009 NE ARG D 149 12451 13796 10162 -2974 -2016 -1410 N ATOM 1010 CZ ARG D 149 2.664 51.881 138.920 1.00 97.08 C ANISOU 1010 CZ ARG D 149 12207 14341 10336 -3164 -2315 -1163 C ATOM 1011 NH1 ARG D 149 3.215 51.773 140.128 1.00 99.01 N ANISOU 1011 NH1 ARG D 149 12498 14870 10251 -3429 -2633 -1180 N ATOM 1012 NH2 ARG D 149 3.327 51.426 137.857 1.00 96.14 N ANISOU 1012 NH2 ARG D 149 11635 14339 10555 -3067 -2287 -871 N ATOM 1013 N MET D 150 -5.222 54.067 141.175 1.00 85.35 N ANISOU 1013 N MET D 150 13117 11306 8005 -1592 -401 -2336 N ATOM 1014 CA MET D 150 -6.160 54.304 142.277 1.00 87.46 C ANISOU 1014 CA MET D 150 13822 11471 7938 -1390 -119 -2490 C ATOM 1015 C MET D 150 -5.966 53.226 143.364 1.00 86.67 C ANISOU 1015 C MET D 150 13663 11732 7536 -1448 -281 -2423 C ATOM 1016 O MET D 150 -5.860 52.055 143.029 1.00 82.81 O ANISOU 1016 O MET D 150 12701 11549 7214 -1377 -394 -2172 O ATOM 1017 CB MET D 150 -7.594 54.263 141.729 1.00 85.16 C ANISOU 1017 CB MET D 150 13395 11088 7871 -903 305 -2361 C ATOM 1018 N ASP D 151 -5.902 53.598 144.653 1.00 89.89 N ANISOU 1018 N ASP D 151 14593 12086 7474 -1576 -286 -2639 N ATOM 1019 CA ASP D 151 -5.964 52.602 145.751 1.00 90.13 C ANISOU 1019 CA ASP D 151 14633 12435 7177 -1544 -354 -2561 C ATOM 1020 C ASP D 151 -7.077 51.586 145.430 1.00 88.03 C ANISOU 1020 C ASP D 151 13978 12328 7139 -1122 -48 -2302 C ATOM 1021 O ASP D 151 -8.081 51.945 144.803 1.00 88.05 O ANISOU 1021 O ASP D 151 13918 12148 7388 -822 300 -2268 O ATOM 1022 CB ASP D 151 -6.212 53.274 147.121 1.00 95.20 C ANISOU 1022 CB ASP D 151 16006 12902 7263 -1600 -224 -2844 C ATOM 1023 N CYS D 152 -6.882 50.315 145.770 1.00 85.74 N ANISOU 1023 N CYS D 152 13399 12384 6794 -1114 -193 -2090 N ATOM 1024 CA CYS D 152 -7.916 49.297 145.532 1.00 81.59 C ANISOU 1024 CA CYS D 152 12546 12000 6453 -795 77 -1845 C ATOM 1025 C CYS D 152 -8.494 48.804 146.881 1.00 82.68 C ANISOU 1025 C CYS D 152 12964 12264 6183 -667 269 -1841 C ATOM 1026 O CYS D 152 -7.968 47.847 147.452 1.00 81.14 O ANISOU 1026 O CYS D 152 12693 12331 5804 -761 61 -1710 O ATOM 1027 CB CYS D 152 -7.334 48.132 144.735 1.00 77.16 C ANISOU 1027 CB CYS D 152 11468 11673 6174 -856 -167 -1575 C ATOM 1028 SG CYS D 152 -8.521 46.784 144.508 1.00 76.69 S ANISOU 1028 SG CYS D 152 11081 11768 6287 -580 113 -1283 S ATOM 1029 N PRO D 153 -9.585 49.434 147.380 1.00 85.43 N ANISOU 1029 N PRO D 153 13637 12430 6392 -415 699 -1950 N ATOM 1030 CA PRO D 153 -9.954 49.151 148.790 1.00 90.49 C ANISOU 1030 CA PRO D 153 14667 13157 6557 -328 880 -1989 C ATOM 1031 C PRO D 153 -10.437 47.736 149.131 1.00 88.08 C ANISOU 1031 C PRO D 153 14063 13150 6250 -197 978 -1697 C ATOM 1032 O PRO D 153 -10.449 47.367 150.322 1.00 91.94 O ANISOU 1032 O PRO D 153 14871 13753 6309 -186 1032 -1707 O ATOM 1033 CB PRO D 153 -11.056 50.200 149.111 1.00 93.79 C ANISOU 1033 CB PRO D 153 15484 13280 6872 -22 1400 -2140 C ATOM 1034 CG PRO D 153 -11.012 51.186 147.987 1.00 92.44 C ANISOU 1034 CG PRO D 153 15227 12842 7054 -16 1401 -2231 C ATOM 1035 CD PRO D 153 -10.470 50.454 146.790 1.00 86.64 C ANISOU 1035 CD PRO D 153 13865 12293 6760 -173 1056 -2027 C ATOM 1036 N ALA D 154 -10.847 46.974 148.127 1.00 81.24 N ANISOU 1036 N ALA D 154 12654 12388 5825 -116 1009 -1446 N ATOM 1037 CA ALA D 154 -11.250 45.580 148.322 1.00 80.75 C ANISOU 1037 CA ALA D 154 12320 12565 5793 -55 1081 -1160 C ATOM 1038 C ALA D 154 -10.105 44.642 148.702 1.00 80.41 C ANISOU 1038 C ALA D 154 12262 12725 5564 -254 696 -1064 C ATOM 1039 O ALA D 154 -10.349 43.591 149.294 1.00 79.60 O ANISOU 1039 O ALA D 154 12140 12788 5314 -196 782 -869 O ATOM 1040 CB ALA D 154 -11.934 45.037 147.067 1.00 77.63 C ANISOU 1040 CB ALA D 154 11403 12196 5896 11 1170 -934 C ATOM 1041 N LEU D 155 -8.878 44.994 148.306 1.00 80.58 N ANISOU 1041 N LEU D 155 12254 12741 5620 -472 291 -1160 N ATOM 1042 CA LEU D 155 -7.705 44.125 148.479 1.00 80.44 C ANISOU 1042 CA LEU D 155 12112 12949 5500 -623 -88 -1004 C ATOM 1043 C LEU D 155 -7.054 44.412 149.838 1.00 83.03 C ANISOU 1043 C LEU D 155 12865 13398 5281 -756 -287 -1132 C ATOM 1044 O LEU D 155 -7.532 45.304 150.574 1.00 84.54 O ANISOU 1044 O LEU D 155 13500 13446 5175 -742 -107 -1374 O ATOM 1045 CB LEU D 155 -6.704 44.337 147.331 1.00 79.10 C ANISOU 1045 CB LEU D 155 11629 12758 5665 -782 -405 -985 C ATOM 1046 CG LEU D 155 -7.025 43.704 145.969 1.00 77.49 C ANISOU 1046 CG LEU D 155 11012 12492 5938 -686 -312 -795 C ATOM 1047 CD1 LEU D 155 -5.910 44.020 144.984 1.00 75.88 C ANISOU 1047 CD1 LEU D 155 10575 12267 5986 -834 -607 -788 C ATOM 1048 CD2 LEU D 155 -7.220 42.186 146.000 1.00 77.29 C ANISOU 1048 CD2 LEU D 155 10827 12601 5937 -577 -237 -499 C ATOM 1049 N PRO D 156 -5.970 43.661 150.185 1.00 82.73 N ANISOU 1049 N PRO D 156 12722 13625 5086 -870 -651 -954 N ATOM 1050 CA PRO D 156 -5.277 44.112 151.427 1.00 88.03 C ANISOU 1050 CA PRO D 156 13804 14433 5209 -1064 -925 -1094 C ATOM 1051 C PRO D 156 -4.648 45.516 151.181 1.00 90.07 C ANISOU 1051 C PRO D 156 14228 14540 5454 -1364 -1170 -1397 C ATOM 1052 O PRO D 156 -4.642 45.988 150.003 1.00 86.30 O ANISOU 1052 O PRO D 156 13479 13886 5425 -1385 -1136 -1441 O ATOM 1053 CB PRO D 156 -4.232 43.005 151.688 1.00 87.26 C ANISOU 1053 CB PRO D 156 13453 14686 5013 -1094 -1278 -774 C ATOM 1054 CG PRO D 156 -4.700 41.806 150.884 1.00 84.24 C ANISOU 1054 CG PRO D 156 12692 14288 5025 -838 -1034 -478 C ATOM 1055 CD PRO D 156 -5.457 42.354 149.707 1.00 78.87 C ANISOU 1055 CD PRO D 156 11839 13321 4803 -794 -777 -611 C ATOM 1056 N PRO D 157 -4.182 46.192 152.253 1.00 94.26 N ANISOU 1056 N PRO D 157 15242 15107 5463 -1609 -1394 -1608 N ATOM 1057 CA PRO D 157 -3.525 47.524 152.212 1.00 97.63 C ANISOU 1057 CA PRO D 157 15942 15374 5777 -1983 -1660 -1912 C ATOM 1058 C PRO D 157 -2.301 47.620 151.275 1.00 97.29 C ANISOU 1058 C PRO D 157 15393 15478 6092 -2257 -2093 -1788 C ATOM 1059 O PRO D 157 -1.607 46.609 151.067 1.00 96.68 O ANISOU 1059 O PRO D 157 14838 15739 6156 -2212 -2327 -1452 O ATOM 1060 CB PRO D 157 -3.062 47.737 153.654 1.00103.11 C ANISOU 1060 CB PRO D 157 17183 16218 5774 -2232 -1934 -2044 C ATOM 1061 CG PRO D 157 -3.880 46.815 154.479 1.00103.51 C ANISOU 1061 CG PRO D 157 17398 16372 5559 -1892 -1619 -1900 C ATOM 1062 CD PRO D 157 -4.253 45.654 153.626 1.00 98.26 C ANISOU 1062 CD PRO D 157 16116 15812 5405 -1567 -1416 -1554 C ATOM 1063 N GLY D 158 -2.060 48.820 150.717 1.00 97.73 N ANISOU 1063 N GLY D 158 15574 15267 6292 -2510 -2152 -2036 N ATOM 1064 CA GLY D 158 -0.970 49.074 149.752 1.00 94.59 C ANISOU 1064 CA GLY D 158 14713 14961 6263 -2781 -2495 -1931 C ATOM 1065 C GLY D 158 -1.298 48.852 148.272 1.00 89.13 C ANISOU 1065 C GLY D 158 13540 14124 6202 -2524 -2240 -1787 C ATOM 1066 O GLY D 158 -0.578 49.339 147.390 1.00 88.33 O ANISOU 1066 O GLY D 158 13167 13982 6409 -2730 -2413 -1766 O ATOM 1067 N TRP D 159 -2.385 48.146 147.968 1.00 84.54 N ANISOU 1067 N TRP D 159 12861 13458 5801 -2105 -1833 -1682 N ATOM 1068 CA TRP D 159 -2.672 47.752 146.577 1.00 77.30 C ANISOU 1068 CA TRP D 159 11488 12449 5430 -1883 -1642 -1509 C ATOM 1069 C TRP D 159 -3.251 48.888 145.742 1.00 75.86 C ANISOU 1069 C TRP D 159 11440 11878 5504 -1870 -1406 -1731 C ATOM 1070 O TRP D 159 -4.089 49.652 146.229 1.00 76.56 O ANISOU 1070 O TRP D 159 11974 11714 5399 -1798 -1146 -1973 O ATOM 1071 CB TRP D 159 -3.607 46.541 146.558 1.00 74.36 C ANISOU 1071 CB TRP D 159 10968 12146 5138 -1514 -1340 -1299 C ATOM 1072 CG TRP D 159 -2.898 45.290 146.936 1.00 73.82 C ANISOU 1072 CG TRP D 159 10656 12423 4969 -1475 -1552 -994 C ATOM 1073 CD1 TRP D 159 -2.639 44.831 148.198 1.00 77.32 C ANISOU 1073 CD1 TRP D 159 11302 13106 4969 -1507 -1698 -935 C ATOM 1074 CD2 TRP D 159 -2.304 44.356 146.041 1.00 71.08 C ANISOU 1074 CD2 TRP D 159 9851 12208 4947 -1373 -1631 -687 C ATOM 1075 NE1 TRP D 159 -1.941 43.654 148.143 1.00 76.40 N ANISOU 1075 NE1 TRP D 159 10854 13270 4903 -1406 -1860 -587 N ATOM 1076 CE2 TRP D 159 -1.720 43.334 146.830 1.00 73.45 C ANISOU 1076 CE2 TRP D 159 10085 12822 4999 -1312 -1803 -432 C ATOM 1077 CE3 TRP D 159 -2.202 44.280 144.642 1.00 67.33 C ANISOU 1077 CE3 TRP D 159 9055 11600 4925 -1305 -1553 -593 C ATOM 1078 CZ2 TRP D 159 -1.038 42.241 146.270 1.00 72.06 C ANISOU 1078 CZ2 TRP D 159 9538 12810 5029 -1155 -1866 -78 C ATOM 1079 CZ3 TRP D 159 -1.542 43.191 144.082 1.00 66.53 C ANISOU 1079 CZ3 TRP D 159 8618 11652 5007 -1170 -1612 -266 C ATOM 1080 CH2 TRP D 159 -0.959 42.180 144.910 1.00 68.66 C ANISOU 1080 CH2 TRP D 159 8835 12218 5032 -1082 -1754 -8 C ATOM 1081 N LYS D 160 -2.818 48.988 144.477 1.00 72.34 N ANISOU 1081 N LYS D 160 10627 11375 5482 -1900 -1462 -1626 N ATOM 1082 CA LYS D 160 -3.452 49.910 143.525 1.00 70.16 C ANISOU 1082 CA LYS D 160 10423 10742 5492 -1815 -1210 -1767 C ATOM 1083 C LYS D 160 -3.870 49.185 142.262 1.00 65.32 C ANISOU 1083 C LYS D 160 9386 10129 5304 -1558 -1049 -1536 C ATOM 1084 O LYS D 160 -3.391 48.090 141.972 1.00 62.05 O ANISOU 1084 O LYS D 160 8630 9946 4997 -1510 -1167 -1284 O ATOM 1085 CB LYS D 160 -2.548 51.073 143.131 1.00 72.09 C ANISOU 1085 CB LYS D 160 10762 10821 5806 -2164 -1419 -1920 C ATOM 1086 N LYS D 161 -4.769 49.850 141.540 1.00 65.31 N ANISOU 1086 N LYS D 161 9457 9846 5509 -1392 -773 -1624 N ATOM 1087 CA LYS D 161 -5.349 49.381 140.292 1.00 63.21 C ANISOU 1087 CA LYS D 161 8871 9535 5611 -1175 -615 -1445 C ATOM 1088 C LYS D 161 -5.260 50.528 139.279 1.00 63.66 C ANISOU 1088 C LYS D 161 8970 9307 5910 -1220 -569 -1544 C ATOM 1089 O LYS D 161 -5.398 51.699 139.647 1.00 67.49 O ANISOU 1089 O LYS D 161 9813 9554 6274 -1284 -485 -1770 O ATOM 1090 CB LYS D 161 -6.822 49.011 140.558 1.00 63.69 C ANISOU 1090 CB LYS D 161 8971 9588 5641 -883 -292 -1406 C ATOM 1091 CG LYS D 161 -7.690 48.568 139.380 1.00 62.68 C ANISOU 1091 CG LYS D 161 8546 9430 5838 -687 -132 -1226 C ATOM 1092 CD LYS D 161 -9.135 48.439 139.877 1.00 64.90 C ANISOU 1092 CD LYS D 161 8867 9737 6053 -448 180 -1190 C ATOM 1093 CE LYS D 161 -9.951 47.368 139.171 1.00 63.09 C ANISOU 1093 CE LYS D 161 8303 9641 6027 -350 255 -941 C ATOM 1094 NZ LYS D 161 -10.889 47.937 138.174 1.00 63.64 N ANISOU 1094 NZ LYS D 161 8220 9605 6355 -196 405 -877 N ATOM 1095 N GLU D 162 -5.062 50.177 138.003 1.00 62.02 N ANISOU 1095 N GLU D 162 8451 9094 6020 -1172 -595 -1371 N ATOM 1096 CA GLU D 162 -5.026 51.134 136.907 1.00 60.71 C ANISOU 1096 CA GLU D 162 8299 8668 6098 -1178 -532 -1412 C ATOM 1097 C GLU D 162 -5.703 50.466 135.677 1.00 55.93 C ANISOU 1097 C GLU D 162 7420 8072 5757 -956 -418 -1205 C ATOM 1098 O GLU D 162 -5.539 49.274 135.440 1.00 50.92 O ANISOU 1098 O GLU D 162 6561 7625 5158 -928 -487 -1024 O ATOM 1099 CB GLU D 162 -3.553 51.484 136.611 1.00 65.02 C ANISOU 1099 CB GLU D 162 8764 9228 6712 -1488 -786 -1406 C ATOM 1100 CG GLU D 162 -3.293 52.569 135.544 1.00 68.49 C ANISOU 1100 CG GLU D 162 9258 9379 7383 -1560 -733 -1450 C ATOM 1101 CD GLU D 162 -1.843 52.628 135.074 1.00 72.20 C ANISOU 1101 CD GLU D 162 9514 9934 7983 -1846 -957 -1346 C ATOM 1102 OE1 GLU D 162 -0.931 52.261 135.849 1.00 77.09 O ANISOU 1102 OE1 GLU D 162 10027 10806 8458 -2070 -1197 -1310 O ATOM 1103 OE2 GLU D 162 -1.610 53.030 133.913 1.00 76.95 O ANISOU 1103 OE2 GLU D 162 10029 10375 8833 -1836 -890 -1267 O ATOM 1104 N GLU D 163 -6.423 51.278 134.908 1.00 55.86 N ANISOU 1104 N GLU D 163 7476 7841 5905 -812 -250 -1231 N ATOM 1105 CA GLU D 163 -7.021 50.915 133.649 1.00 54.99 C ANISOU 1105 CA GLU D 163 7158 7715 6021 -653 -186 -1053 C ATOM 1106 C GLU D 163 -6.401 51.802 132.559 1.00 53.46 C ANISOU 1106 C GLU D 163 7002 7295 6015 -719 -212 -1060 C ATOM 1107 O GLU D 163 -6.185 52.998 132.774 1.00 54.49 O ANISOU 1107 O GLU D 163 7376 7202 6125 -781 -157 -1220 O ATOM 1108 CB GLU D 163 -8.540 51.103 133.721 1.00 56.89 C ANISOU 1108 CB GLU D 163 7399 7945 6271 -391 36 -1018 C ATOM 1109 CG GLU D 163 -9.257 50.675 132.432 1.00 57.52 C ANISOU 1109 CG GLU D 163 7242 8062 6551 -271 46 -809 C ATOM 1110 CD GLU D 163 -10.793 50.750 132.502 1.00 61.96 C ANISOU 1110 CD GLU D 163 7690 8709 7142 -29 233 -700 C ATOM 1111 OE1 GLU D 163 -11.432 51.131 131.481 1.00 66.43 O ANISOU 1111 OE1 GLU D 163 8144 9229 7867 105 266 -569 O ATOM 1112 OE2 GLU D 163 -11.374 50.425 133.557 1.00 66.58 O ANISOU 1112 OE2 GLU D 163 8274 9432 7590 34 350 -713 O ATOM 1113 N VAL D 164 -6.109 51.214 131.409 1.00 48.91 N ANISOU 1113 N VAL D 164 6237 6748 5596 -713 -274 -889 N ATOM 1114 CA VAL D 164 -5.424 51.911 130.279 1.00 48.29 C ANISOU 1114 CA VAL D 164 6180 6473 5694 -774 -284 -853 C ATOM 1115 C VAL D 164 -6.168 51.564 128.979 1.00 46.37 C ANISOU 1115 C VAL D 164 5843 6199 5575 -597 -229 -682 C ATOM 1116 O VAL D 164 -6.237 50.367 128.590 1.00 43.47 O ANISOU 1116 O VAL D 164 5342 5981 5193 -584 -288 -543 O ATOM 1117 CB VAL D 164 -3.947 51.466 130.158 1.00 48.75 C ANISOU 1117 CB VAL D 164 6109 6627 5786 -982 -431 -781 C ATOM 1118 CG1 VAL D 164 -3.235 52.138 128.957 1.00 49.99 C ANISOU 1118 CG1 VAL D 164 6267 6592 6132 -1042 -400 -709 C ATOM 1119 CG2 VAL D 164 -3.185 51.685 131.462 1.00 51.24 C ANISOU 1119 CG2 VAL D 164 6469 7050 5947 -1204 -560 -911 C ATOM 1120 N ILE D 165 -6.654 52.607 128.295 1.00 46.35 N ANISOU 1120 N ILE D 165 5952 5985 5672 -478 -124 -687 N ATOM 1121 CA ILE D 165 -7.419 52.491 127.082 1.00 46.22 C ANISOU 1121 CA ILE D 165 5872 5944 5743 -316 -101 -521 C ATOM 1122 C ILE D 165 -6.504 52.111 125.900 1.00 44.98 C ANISOU 1122 C ILE D 165 5699 5728 5660 -408 -165 -405 C ATOM 1123 O ILE D 165 -5.418 52.644 125.729 1.00 45.72 O ANISOU 1123 O ILE D 165 5859 5690 5822 -531 -152 -441 O ATOM 1124 CB ILE D 165 -8.209 53.798 126.780 1.00 49.36 C ANISOU 1124 CB ILE D 165 6404 6139 6211 -110 48 -529 C ATOM 1125 CG1 ILE D 165 -9.219 54.109 127.892 1.00 52.21 C ANISOU 1125 CG1 ILE D 165 6787 6559 6491 55 181 -603 C ATOM 1126 CG2 ILE D 165 -8.936 53.716 125.426 1.00 49.81 C ANISOU 1126 CG2 ILE D 165 6376 6205 6343 46 25 -317 C ATOM 1127 CD1 ILE D 165 -10.286 53.056 128.090 1.00 50.86 C ANISOU 1127 CD1 ILE D 165 6357 6691 6275 144 145 -464 C ATOM 1128 N ARG D 166 -6.975 51.183 125.074 1.00 43.63 N ANISOU 1128 N ARG D 166 5461 5652 5463 -359 -222 -254 N ATOM 1129 CA ARG D 166 -6.279 50.812 123.836 1.00 42.87 C ANISOU 1129 CA ARG D 166 5428 5466 5394 -392 -235 -132 C ATOM 1130 C ARG D 166 -6.542 51.868 122.748 1.00 43.77 C ANISOU 1130 C ARG D 166 5661 5378 5589 -283 -176 -68 C ATOM 1131 O ARG D 166 -7.679 52.184 122.493 1.00 43.39 O ANISOU 1131 O ARG D 166 5598 5356 5531 -147 -193 -12 O ATOM 1132 CB ARG D 166 -6.748 49.447 123.404 1.00 41.93 C ANISOU 1132 CB ARG D 166 5297 5476 5159 -407 -315 -20 C ATOM 1133 CG ARG D 166 -6.325 48.343 124.409 1.00 40.12 C ANISOU 1133 CG ARG D 166 4995 5403 4845 -495 -339 -51 C ATOM 1134 CD ARG D 166 -6.775 46.966 123.874 1.00 39.89 C ANISOU 1134 CD ARG D 166 5048 5426 4683 -535 -391 59 C ATOM 1135 NE ARG D 166 -6.201 45.871 124.681 1.00 38.66 N ANISOU 1135 NE ARG D 166 4880 5363 4443 -581 -372 67 N ATOM 1136 CZ ARG D 166 -5.779 44.697 124.233 1.00 37.93 C ANISOU 1136 CZ ARG D 166 4946 5216 4247 -593 -333 166 C ATOM 1137 NH1 ARG D 166 -5.953 44.329 122.933 1.00 36.52 N ANISOU 1137 NH1 ARG D 166 4998 4883 3994 -603 -323 247 N ATOM 1138 NH2 ARG D 166 -5.223 43.840 125.123 1.00 37.25 N ANISOU 1138 NH2 ARG D 166 4832 5221 4100 -585 -294 191 N ATOM 1139 N LYS D 167 -5.486 52.390 122.111 1.00 44.29 N ANISOU 1139 N LYS D 167 5826 5264 5737 -335 -100 -43 N ATOM 1140 CA LYS D 167 -5.606 53.637 121.329 1.00 45.89 C ANISOU 1140 CA LYS D 167 6178 5230 6026 -241 -6 -6 C ATOM 1141 C LYS D 167 -5.809 53.456 119.818 1.00 46.13 C ANISOU 1141 C LYS D 167 6330 5185 6012 -144 -8 173 C ATOM 1142 O LYS D 167 -6.209 54.388 119.111 1.00 48.51 O ANISOU 1142 O LYS D 167 6756 5325 6349 -13 46 245 O ATOM 1143 CB LYS D 167 -4.382 54.514 121.576 1.00 47.58 C ANISOU 1143 CB LYS D 167 6453 5264 6359 -397 93 -83 C ATOM 1144 CG LYS D 167 -4.163 54.886 123.048 1.00 48.92 C ANISOU 1144 CG LYS D 167 6585 5474 6527 -538 68 -278 C ATOM 1145 N SER D 168 -5.551 52.263 119.333 1.00 45.57 N ANISOU 1145 N SER D 168 6270 5210 5834 -195 -62 250 N ATOM 1146 CA SER D 168 -5.597 51.965 117.917 1.00 46.72 C ANISOU 1146 CA SER D 168 6611 5265 5874 -139 -60 402 C ATOM 1147 C SER D 168 -5.819 50.499 117.703 1.00 46.12 C ANISOU 1147 C SER D 168 6591 5316 5615 -202 -157 443 C ATOM 1148 O SER D 168 -5.867 49.682 118.663 1.00 44.94 O ANISOU 1148 O SER D 168 6309 5323 5442 -281 -208 369 O ATOM 1149 CB SER D 168 -4.261 52.384 117.309 1.00 48.99 C ANISOU 1149 CB SER D 168 7008 5357 6248 -162 129 459 C ATOM 1150 OG SER D 168 -3.203 51.679 117.924 1.00 49.11 O ANISOU 1150 OG SER D 168 6897 5456 6304 -263 192 435 O ATOM 1151 N GLY D 169 -6.052 50.164 116.447 1.00 45.52 N ANISOU 1151 N GLY D 169 6760 5158 5376 -178 -189 561 N ATOM 1152 CA GLY D 169 -6.163 48.785 115.991 1.00 44.25 C ANISOU 1152 CA GLY D 169 6801 5023 4988 -266 -252 599 C ATOM 1153 C GLY D 169 -7.546 48.214 116.132 1.00 43.39 C ANISOU 1153 C GLY D 169 6637 5104 4745 -374 -506 607 C ATOM 1154 O GLY D 169 -8.502 48.908 116.427 1.00 43.80 O ANISOU 1154 O GLY D 169 6468 5295 4877 -333 -629 625 O ATOM 1155 N LEU D 170 -7.642 46.912 115.957 1.00 44.85 N ANISOU 1155 N LEU D 170 7022 5293 4724 -515 -564 609 N ATOM 1156 CA LEU D 170 -8.936 46.254 115.954 1.00 46.05 C ANISOU 1156 CA LEU D 170 7149 5622 4722 -701 -827 641 C ATOM 1157 C LEU D 170 -9.650 46.414 117.286 1.00 45.62 C ANISOU 1157 C LEU D 170 6676 5818 4839 -716 -895 592 C ATOM 1158 O LEU D 170 -10.863 46.549 117.300 1.00 45.56 O ANISOU 1158 O LEU D 170 6474 6018 4818 -783 -1093 673 O ATOM 1159 CB LEU D 170 -8.785 44.765 115.617 1.00 49.44 C ANISOU 1159 CB LEU D 170 7953 5942 4886 -889 -837 629 C ATOM 1160 CG LEU D 170 -8.036 44.434 114.325 1.00 53.62 C ANISOU 1160 CG LEU D 170 8998 6184 5189 -853 -707 672 C ATOM 1161 CD1 LEU D 170 -7.730 42.938 114.267 1.00 57.35 C ANISOU 1161 CD1 LEU D 170 9882 6490 5418 -985 -622 637 C ATOM 1162 CD2 LEU D 170 -8.853 44.876 113.134 1.00 57.80 C ANISOU 1162 CD2 LEU D 170 9701 6726 5532 -933 -936 768 C ATOM 1163 N SER D 171 -8.893 46.402 118.396 1.00 42.58 N ANISOU 1163 N SER D 171 6147 5431 4600 -649 -727 484 N ATOM 1164 CA SER D 171 -9.480 46.462 119.766 1.00 41.56 C ANISOU 1164 CA SER D 171 5687 5516 4586 -657 -752 422 C ATOM 1165 C SER D 171 -9.458 47.907 120.366 1.00 41.48 C ANISOU 1165 C SER D 171 5451 5520 4786 -469 -660 367 C ATOM 1166 O SER D 171 -9.606 48.112 121.588 1.00 39.09 O ANISOU 1166 O SER D 171 4953 5330 4569 -436 -607 280 O ATOM 1167 CB SER D 171 -8.665 45.493 120.634 1.00 39.25 C ANISOU 1167 CB SER D 171 5440 5208 4264 -710 -643 346 C ATOM 1168 OG SER D 171 -7.345 45.960 120.814 1.00 38.25 O ANISOU 1168 OG SER D 171 5324 4960 4246 -590 -473 298 O ATOM 1169 N ALA D 172 -9.310 48.924 119.489 1.00 42.64 N ANISOU 1169 N ALA D 172 5683 5526 4989 -346 -627 419 N ATOM 1170 CA ALA D 172 -9.248 50.302 119.936 1.00 41.80 C ANISOU 1170 CA ALA D 172 5473 5352 5057 -180 -510 366 C ATOM 1171 C ALA D 172 -10.526 50.612 120.743 1.00 42.90 C ANISOU 1171 C ALA D 172 5356 5698 5243 -88 -551 390 C ATOM 1172 O ALA D 172 -11.605 50.159 120.389 1.00 43.12 O ANISOU 1172 O ALA D 172 5262 5920 5200 -118 -704 531 O ATOM 1173 CB ALA D 172 -9.138 51.247 118.710 1.00 44.35 C ANISOU 1173 CB ALA D 172 5960 5488 5402 -57 -477 470 C ATOM 1174 N GLY D 173 -10.417 51.339 121.837 1.00 40.78 N ANISOU 1174 N GLY D 173 5013 5402 5078 7 -409 266 N ATOM 1175 CA GLY D 173 -11.584 51.639 122.625 1.00 43.91 C ANISOU 1175 CA GLY D 173 5198 5976 5510 146 -375 303 C ATOM 1176 C GLY D 173 -11.748 50.675 123.842 1.00 43.66 C ANISOU 1176 C GLY D 173 5032 6140 5415 20 -380 221 C ATOM 1177 O GLY D 173 -12.330 51.069 124.817 1.00 41.19 O ANISOU 1177 O GLY D 173 4607 5911 5131 146 -263 187 O ATOM 1178 N LYS D 174 -11.254 49.435 123.729 1.00 41.98 N ANISOU 1178 N LYS D 174 4872 5974 5102 -197 -487 209 N ATOM 1179 CA LYS D 174 -11.244 48.466 124.883 1.00 43.31 C ANISOU 1179 CA LYS D 174 4967 6292 5196 -316 -476 140 C ATOM 1180 C LYS D 174 -10.123 48.898 125.820 1.00 41.36 C ANISOU 1180 C LYS D 174 4818 5930 4964 -303 -364 -44 C ATOM 1181 O LYS D 174 -9.350 49.784 125.506 1.00 39.87 O ANISOU 1181 O LYS D 174 4745 5554 4847 -262 -313 -111 O ATOM 1182 CB LYS D 174 -11.029 47.013 124.390 1.00 42.16 C ANISOU 1182 CB LYS D 174 4920 6176 4922 -531 -598 203 C ATOM 1183 CG LYS D 174 -12.022 46.489 123.317 1.00 45.05 C ANISOU 1183 CG LYS D 174 5267 6632 5216 -651 -772 376 C ATOM 1184 CD LYS D 174 -13.497 46.545 123.654 1.00 48.39 C ANISOU 1184 CD LYS D 174 5380 7330 5675 -651 -835 513 C ATOM 1185 N SER D 175 -10.027 48.258 126.977 1.00 42.10 N ANISOU 1185 N SER D 175 4868 6148 4977 -368 -341 -112 N ATOM 1186 CA SER D 175 -9.034 48.580 128.001 1.00 41.98 C ANISOU 1186 CA SER D 175 4930 6088 4930 -397 -288 -271 C ATOM 1187 C SER D 175 -8.366 47.331 128.617 1.00 40.52 C ANISOU 1187 C SER D 175 4748 6017 4631 -520 -341 -260 C ATOM 1188 O SER D 175 -8.897 46.194 128.520 1.00 36.96 O ANISOU 1188 O SER D 175 4265 5668 4110 -574 -373 -154 O ATOM 1189 CB SER D 175 -9.680 49.395 129.145 1.00 45.02 C ANISOU 1189 CB SER D 175 5311 6508 5285 -282 -164 -382 C ATOM 1190 OG SER D 175 -10.793 48.696 129.680 1.00 47.12 O ANISOU 1190 OG SER D 175 5430 6982 5489 -244 -126 -294 O ATOM 1191 N ASP D 176 -7.222 47.589 129.260 1.00 40.02 N ANISOU 1191 N ASP D 176 4728 5934 4543 -574 -354 -354 N ATOM 1192 CA ASP D 176 -6.502 46.599 130.058 1.00 39.94 C ANISOU 1192 CA ASP D 176 4699 6058 4415 -642 -399 -327 C ATOM 1193 C ASP D 176 -6.468 47.102 131.496 1.00 42.91 C ANISOU 1193 C ASP D 176 5100 6528 4675 -667 -398 -472 C ATOM 1194 O ASP D 176 -6.273 48.312 131.759 1.00 43.30 O ANISOU 1194 O ASP D 176 5229 6476 4746 -691 -386 -616 O ATOM 1195 CB ASP D 176 -5.082 46.353 129.545 1.00 40.10 C ANISOU 1195 CB ASP D 176 4708 6037 4488 -684 -441 -247 C ATOM 1196 CG ASP D 176 -5.093 45.794 128.094 1.00 40.13 C ANISOU 1196 CG ASP D 176 4780 5911 4555 -638 -400 -107 C ATOM 1197 OD1 ASP D 176 -5.193 44.553 127.912 1.00 39.56 O ANISOU 1197 OD1 ASP D 176 4778 5859 4394 -623 -379 3 O ATOM 1198 OD2 ASP D 176 -5.095 46.610 127.146 1.00 40.05 O ANISOU 1198 OD2 ASP D 176 4806 5752 4655 -621 -379 -116 O ATOM 1199 N VAL D 177 -6.631 46.168 132.410 1.00 41.76 N ANISOU 1199 N VAL D 177 4941 6546 4377 -673 -402 -435 N ATOM 1200 CA VAL D 177 -6.568 46.491 133.846 1.00 44.55 C ANISOU 1200 CA VAL D 177 5367 7005 4554 -701 -406 -562 C ATOM 1201 C VAL D 177 -5.299 45.879 134.469 1.00 44.88 C ANISOU 1201 C VAL D 177 5379 7190 4481 -789 -546 -505 C ATOM 1202 O VAL D 177 -4.936 44.704 134.175 1.00 45.21 O ANISOU 1202 O VAL D 177 5353 7301 4523 -752 -560 -325 O ATOM 1203 CB VAL D 177 -7.900 46.062 134.511 1.00 45.29 C ANISOU 1203 CB VAL D 177 5465 7195 4546 -612 -270 -545 C ATOM 1204 CG1 VAL D 177 -7.817 46.080 136.046 1.00 48.65 C ANISOU 1204 CG1 VAL D 177 6014 7743 4725 -624 -251 -644 C ATOM 1205 CG2 VAL D 177 -8.982 47.025 134.061 1.00 46.89 C ANISOU 1205 CG2 VAL D 177 5655 7293 4866 -496 -137 -590 C ATOM 1206 N TYR D 178 -4.615 46.688 135.293 1.00 47.09 N ANISOU 1206 N TYR D 178 5729 7507 4653 -908 -650 -641 N ATOM 1207 CA TYR D 178 -3.408 46.286 135.986 1.00 49.50 C ANISOU 1207 CA TYR D 178 5963 8010 4835 -1016 -833 -569 C ATOM 1208 C TYR D 178 -3.558 46.459 137.495 1.00 50.60 C ANISOU 1208 C TYR D 178 6270 8278 4675 -1085 -892 -699 C ATOM 1209 O TYR D 178 -4.176 47.420 137.953 1.00 49.27 O ANISOU 1209 O TYR D 178 6320 7984 4416 -1116 -815 -913 O ATOM 1210 CB TYR D 178 -2.255 47.176 135.527 1.00 54.10 C ANISOU 1210 CB TYR D 178 6461 8548 5544 -1193 -972 -592 C ATOM 1211 CG TYR D 178 -2.055 47.128 134.027 1.00 53.45 C ANISOU 1211 CG TYR D 178 6256 8319 5733 -1117 -885 -467 C ATOM 1212 CD1 TYR D 178 -1.502 45.996 133.427 1.00 54.94 C ANISOU 1212 CD1 TYR D 178 6285 8591 5995 -996 -859 -219 C ATOM 1213 CD2 TYR D 178 -2.462 48.172 133.196 1.00 54.91 C ANISOU 1213 CD2 TYR D 178 6532 8256 6073 -1132 -796 -581 C ATOM 1214 CE1 TYR D 178 -1.306 45.910 132.048 1.00 52.76 C ANISOU 1214 CE1 TYR D 178 5964 8161 5919 -915 -753 -106 C ATOM 1215 CE2 TYR D 178 -2.262 48.098 131.806 1.00 53.55 C ANISOU 1215 CE2 TYR D 178 6281 7954 6111 -1058 -717 -453 C ATOM 1216 CZ TYR D 178 -1.663 46.966 131.238 1.00 52.88 C ANISOU 1216 CZ TYR D 178 6058 7959 6074 -960 -696 -224 C ATOM 1217 OH TYR D 178 -1.480 46.818 129.843 1.00 50.88 O ANISOU 1217 OH TYR D 178 5798 7554 5979 -868 -585 -97 O ATOM 1218 N TYR D 179 -2.984 45.529 138.243 1.00 51.11 N ANISOU 1218 N TYR D 179 6268 8579 4570 -1083 -1007 -556 N ATOM 1219 CA TYR D 179 -2.791 45.719 139.698 1.00 54.79 C ANISOU 1219 CA TYR D 179 6903 9209 4703 -1194 -1136 -659 C ATOM 1220 C TYR D 179 -1.315 45.903 140.077 1.00 58.19 C ANISOU 1220 C TYR D 179 7197 9858 5054 -1408 -1454 -584 C ATOM 1221 O TYR D 179 -0.418 45.334 139.441 1.00 56.28 O ANISOU 1221 O TYR D 179 6661 9737 4984 -1371 -1537 -341 O ATOM 1222 CB TYR D 179 -3.409 44.556 140.458 1.00 53.44 C ANISOU 1222 CB TYR D 179 6792 9173 4339 -1030 -1029 -539 C ATOM 1223 CG TYR D 179 -4.924 44.568 140.421 1.00 52.37 C ANISOU 1223 CG TYR D 179 6789 8884 4224 -891 -741 -627 C ATOM 1224 CD1 TYR D 179 -5.618 44.056 139.321 1.00 50.02 C ANISOU 1224 CD1 TYR D 179 6355 8467 4181 -779 -581 -515 C ATOM 1225 CD2 TYR D 179 -5.667 45.083 141.463 1.00 54.26 C ANISOU 1225 CD2 TYR D 179 7285 9111 4218 -876 -623 -798 C ATOM 1226 CE1 TYR D 179 -7.009 44.074 139.263 1.00 49.53 C ANISOU 1226 CE1 TYR D 179 6332 8328 4158 -680 -349 -545 C ATOM 1227 CE2 TYR D 179 -7.055 45.086 141.413 1.00 54.28 C ANISOU 1227 CE2 TYR D 179 7333 9019 4271 -720 -331 -818 C ATOM 1228 CZ TYR D 179 -7.719 44.588 140.302 1.00 50.94 C ANISOU 1228 CZ TYR D 179 6693 8528 4134 -635 -213 -677 C ATOM 1229 OH TYR D 179 -9.084 44.556 140.257 1.00 50.72 O ANISOU 1229 OH TYR D 179 6632 8472 4167 -512 40 -646 O ATOM 1230 N PHE D 180 -1.092 46.675 141.141 1.00 63.03 N ANISOU 1230 N PHE D 180 8035 10530 5383 -1631 -1622 -775 N ATOM 1231 CA PHE D 180 0.238 46.862 141.740 1.00 68.08 C ANISOU 1231 CA PHE D 180 8552 11442 5870 -1908 -1990 -701 C ATOM 1232 C PHE D 180 0.202 46.552 143.219 1.00 70.83 C ANISOU 1232 C PHE D 180 9126 12008 5777 -1962 -2134 -736 C ATOM 1233 O PHE D 180 -0.570 47.170 143.959 1.00 70.74 O ANISOU 1233 O PHE D 180 9534 11837 5507 -2012 -2034 -1009 O ATOM 1234 CB PHE D 180 0.706 48.285 141.520 1.00 71.83 C ANISOU 1234 CB PHE D 180 9141 11755 6395 -2253 -2127 -921 C ATOM 1235 CG PHE D 180 0.853 48.619 140.075 1.00 70.33 C ANISOU 1235 CG PHE D 180 8734 11367 6620 -2209 -1996 -860 C ATOM 1236 CD1 PHE D 180 2.013 48.264 139.386 1.00 71.52 C ANISOU 1236 CD1 PHE D 180 8453 11716 7002 -2261 -2139 -577 C ATOM 1237 CD2 PHE D 180 -0.193 49.220 139.376 1.00 68.63 C ANISOU 1237 CD2 PHE D 180 8729 10785 6560 -2069 -1703 -1041 C ATOM 1238 CE1 PHE D 180 2.133 48.540 138.015 1.00 69.43 C ANISOU 1238 CE1 PHE D 180 8025 11256 7099 -2196 -1980 -509 C ATOM 1239 CE2 PHE D 180 -0.080 49.504 138.011 1.00 66.53 C ANISOU 1239 CE2 PHE D 180 8290 10339 6647 -2014 -1586 -967 C ATOM 1240 CZ PHE D 180 1.088 49.170 137.333 1.00 67.11 C ANISOU 1240 CZ PHE D 180 7987 10583 6928 -2088 -1719 -716 C ATOM 1241 N SER D 181 1.026 45.580 143.623 1.00 73.24 N ANISOU 1241 N SER D 181 9169 12669 5989 -1912 -2337 -435 N ATOM 1242 CA SER D 181 1.214 45.171 145.028 1.00 76.94 C ANISOU 1242 CA SER D 181 9802 13418 6012 -1964 -2539 -391 C ATOM 1243 C SER D 181 1.791 46.309 145.882 1.00 81.45 C ANISOU 1243 C SER D 181 10616 14069 6261 -2411 -2887 -623 C ATOM 1244 O SER D 181 2.132 47.360 145.346 1.00 80.88 O ANISOU 1244 O SER D 181 10547 13836 6347 -2687 -2972 -788 O ATOM 1245 CB SER D 181 2.164 43.955 145.093 1.00 77.75 C ANISOU 1245 CB SER D 181 9501 13901 6137 -1799 -2705 47 C ATOM 1246 OG SER D 181 3.512 44.338 144.785 1.00 81.70 O ANISOU 1246 OG SER D 181 9613 14656 6770 -2038 -3041 219 O ATOM 1247 N PRO D 182 1.888 46.103 147.215 1.00 86.40 N ANISOU 1247 N PRO D 182 11495 14924 6408 -2503 -3089 -638 N ATOM 1248 CA PRO D 182 2.690 46.986 148.095 1.00 92.32 C ANISOU 1248 CA PRO D 182 12448 15843 6785 -2992 -3532 -789 C ATOM 1249 C PRO D 182 4.141 47.118 147.619 1.00 95.22 C ANISOU 1249 C PRO D 182 12275 16538 7365 -3284 -3945 -529 C ATOM 1250 O PRO D 182 4.634 48.262 147.383 1.00 97.55 O ANISOU 1250 O PRO D 182 12630 16726 7707 -3725 -4145 -721 O ATOM 1251 CB PRO D 182 2.619 46.282 149.463 1.00 95.32 C ANISOU 1251 CB PRO D 182 13063 16505 6647 -2922 -3670 -700 C ATOM 1252 CG PRO D 182 1.970 44.963 149.228 1.00 91.33 C ANISOU 1252 CG PRO D 182 12386 16011 6303 -2404 -3319 -442 C ATOM 1253 CD PRO D 182 1.086 45.172 148.034 1.00 86.29 C ANISOU 1253 CD PRO D 182 11708 14960 6118 -2198 -2885 -573 C ATOM 1254 N SER D 183 4.788 45.939 147.475 1.00 96.20 N ANISOU 1254 N SER D 183 11885 17042 7622 -3020 -4031 -73 N ATOM 1255 CA SER D 183 6.092 45.784 146.813 1.00 98.18 C ANISOU 1255 CA SER D 183 11487 17630 8185 -3118 -4290 298 C ATOM 1256 C SER D 183 6.141 46.590 145.515 1.00 96.20 C ANISOU 1256 C SER D 183 11094 17062 8393 -3232 -4115 172 C ATOM 1257 O SER D 183 7.143 47.206 145.183 1.00100.26 O ANISOU 1257 O SER D 183 11284 17749 9060 -3590 -4394 271 O ATOM 1258 CB SER D 183 6.333 44.301 146.474 1.00 95.57 C ANISOU 1258 CB SER D 183 10735 17530 8047 -2592 -4123 774 C ATOM 1259 N GLY D 184 5.046 46.578 144.782 1.00 89.69 N ANISOU 1259 N GLY D 184 10501 15792 7783 -2938 -3657 -21 N ATOM 1260 CA GLY D 184 4.934 47.353 143.567 1.00 87.93 C ANISOU 1260 CA GLY D 184 10226 15231 7952 -3006 -3460 -157 C ATOM 1261 C GLY D 184 5.062 46.528 142.298 1.00 83.33 C ANISOU 1261 C GLY D 184 9231 14620 7809 -2615 -3183 149 C ATOM 1262 O GLY D 184 5.085 47.104 141.225 1.00 81.77 O ANISOU 1262 O GLY D 184 8953 14180 7934 -2658 -3032 89 O ATOM 1263 N LYS D 185 5.142 45.195 142.404 1.00 82.55 N ANISOU 1263 N LYS D 185 8931 14734 7701 -2233 -3095 473 N ATOM 1264 CA LYS D 185 5.099 44.318 141.216 1.00 78.52 C ANISOU 1264 CA LYS D 185 8182 14105 7544 -1825 -2764 727 C ATOM 1265 C LYS D 185 3.732 44.411 140.495 1.00 72.80 C ANISOU 1265 C LYS D 185 7807 12903 6948 -1650 -2377 452 C ATOM 1266 O LYS D 185 2.695 44.529 141.161 1.00 69.94 O ANISOU 1266 O LYS D 185 7823 12392 6359 -1648 -2293 197 O ATOM 1267 CB LYS D 185 5.384 42.872 141.629 1.00 79.92 C ANISOU 1267 CB LYS D 185 8198 14551 7616 -1455 -2727 1107 C ATOM 1268 N LYS D 186 3.743 44.375 139.157 1.00 69.99 N ANISOU 1268 N LYS D 186 7316 12335 6940 -1507 -2148 526 N ATOM 1269 CA LYS D 186 2.522 44.524 138.346 1.00 66.73 C ANISOU 1269 CA LYS D 186 7176 11513 6663 -1376 -1836 306 C ATOM 1270 C LYS D 186 1.862 43.184 138.031 1.00 63.57 C ANISOU 1270 C LYS D 186 6855 11023 6274 -1017 -1572 462 C ATOM 1271 O LYS D 186 2.556 42.204 137.727 1.00 63.34 O ANISOU 1271 O LYS D 186 6629 11122 6313 -798 -1518 785 O ATOM 1272 CB LYS D 186 2.788 45.250 137.014 1.00 68.39 C ANISOU 1272 CB LYS D 186 7273 11510 7202 -1438 -1734 283 C ATOM 1273 N PHE D 187 0.522 43.161 138.077 1.00 59.00 N ANISOU 1273 N PHE D 187 6570 10214 5631 -962 -1390 251 N ATOM 1274 CA PHE D 187 -0.256 41.977 137.740 1.00 55.63 C ANISOU 1274 CA PHE D 187 6261 9662 5212 -715 -1149 364 C ATOM 1275 C PHE D 187 -1.221 42.263 136.598 1.00 51.43 C ANISOU 1275 C PHE D 187 5842 8818 4880 -695 -950 228 C ATOM 1276 O PHE D 187 -1.917 43.275 136.611 1.00 50.76 O ANISOU 1276 O PHE D 187 5857 8614 4815 -815 -943 -14 O ATOM 1277 CB PHE D 187 -0.998 41.458 138.966 1.00 55.34 C ANISOU 1277 CB PHE D 187 6423 9716 4886 -682 -1129 319 C ATOM 1278 CG PHE D 187 -0.055 41.070 140.058 1.00 59.03 C ANISOU 1278 CG PHE D 187 6797 10508 5121 -678 -1341 493 C ATOM 1279 CD1 PHE D 187 0.449 42.033 140.897 1.00 60.73 C ANISOU 1279 CD1 PHE D 187 6999 10906 5168 -920 -1610 354 C ATOM 1280 CD2 PHE D 187 0.443 39.781 140.127 1.00 59.69 C ANISOU 1280 CD2 PHE D 187 6807 10708 5165 -440 -1283 820 C ATOM 1281 CE1 PHE D 187 1.401 41.708 141.858 1.00 65.06 C ANISOU 1281 CE1 PHE D 187 7423 11807 5489 -952 -1870 545 C ATOM 1282 CE2 PHE D 187 1.388 39.439 141.075 1.00 63.82 C ANISOU 1282 CE2 PHE D 187 7191 11573 5484 -405 -1500 1038 C ATOM 1283 CZ PHE D 187 1.872 40.409 141.946 1.00 66.01 C ANISOU 1283 CZ PHE D 187 7411 12089 5581 -676 -1821 906 C ATOM 1284 N ARG D 188 -1.263 41.351 135.636 1.00 49.30 N ANISOU 1284 N ARG D 188 5586 8413 4730 -532 -786 399 N ATOM 1285 CA ARG D 188 -2.050 41.553 134.435 1.00 46.79 C ANISOU 1285 CA ARG D 188 5367 7829 4580 -532 -645 311 C ATOM 1286 C ARG D 188 -3.201 40.605 134.292 1.00 46.76 C ANISOU 1286 C ARG D 188 5556 7701 4509 -481 -493 332 C ATOM 1287 O ARG D 188 -3.934 40.725 133.308 1.00 47.08 O ANISOU 1287 O ARG D 188 5673 7555 4660 -515 -416 277 O ATOM 1288 CB ARG D 188 -1.167 41.399 133.178 1.00 47.34 C ANISOU 1288 CB ARG D 188 5357 7792 4836 -440 -575 474 C ATOM 1289 CG ARG D 188 0.066 42.248 133.202 1.00 49.10 C ANISOU 1289 CG ARG D 188 5332 8160 5164 -516 -711 517 C ATOM 1290 CD ARG D 188 0.616 42.428 131.804 1.00 48.09 C ANISOU 1290 CD ARG D 188 5152 7870 5248 -449 -589 621 C ATOM 1291 NE ARG D 188 1.176 41.197 131.273 1.00 47.14 N ANISOU 1291 NE ARG D 188 5064 7717 5129 -197 -409 899 N ATOM 1292 CZ ARG D 188 1.195 40.868 130.000 1.00 44.71 C ANISOU 1292 CZ ARG D 188 4905 7171 4909 -71 -208 979 C ATOM 1293 NH1 ARG D 188 0.593 41.648 129.068 1.00 44.33 N ANISOU 1293 NH1 ARG D 188 4972 6913 4957 -182 -186 809 N ATOM 1294 NH2 ARG D 188 1.758 39.730 129.664 1.00 45.03 N ANISOU 1294 NH2 ARG D 188 5034 7163 4910 185 -12 1235 N ATOM 1295 N SER D 189 -3.353 39.628 135.189 1.00 45.11 N ANISOU 1295 N SER D 189 5431 7591 4115 -420 -456 437 N ATOM 1296 CA SER D 189 -4.454 38.705 135.098 1.00 44.71 C ANISOU 1296 CA SER D 189 5568 7419 3999 -432 -312 470 C ATOM 1297 C SER D 189 -4.847 38.165 136.446 1.00 46.92 C ANISOU 1297 C SER D 189 5916 7849 4060 -424 -290 502 C ATOM 1298 O SER D 189 -4.030 38.170 137.395 1.00 45.88 O ANISOU 1298 O SER D 189 5726 7914 3790 -355 -389 564 O ATOM 1299 CB SER D 189 -4.124 37.517 134.222 1.00 46.37 C ANISOU 1299 CB SER D 189 5953 7439 4225 -330 -179 664 C ATOM 1300 OG SER D 189 -3.237 36.611 134.879 1.00 48.37 O ANISOU 1300 OG SER D 189 6245 7784 4349 -150 -139 881 O ATOM 1301 N LYS D 190 -6.069 37.634 136.486 1.00 47.11 N ANISOU 1301 N LYS D 190 6059 7793 4045 -507 -166 494 N ATOM 1302 CA LYS D 190 -6.580 36.993 137.705 1.00 50.55 C ANISOU 1302 CA LYS D 190 6591 8343 4271 -504 -87 554 C ATOM 1303 C LYS D 190 -5.708 35.806 138.152 1.00 52.96 C ANISOU 1303 C LYS D 190 7036 8662 4422 -352 -48 786 C ATOM 1304 O LYS D 190 -5.291 35.801 139.306 1.00 54.67 O ANISOU 1304 O LYS D 190 7240 9080 4449 -274 -108 830 O ATOM 1305 CB LYS D 190 -8.060 36.600 137.590 1.00 51.25 C ANISOU 1305 CB LYS D 190 6736 8359 4378 -654 53 549 C ATOM 1306 CG LYS D 190 -8.604 36.090 138.914 1.00 53.94 C ANISOU 1306 CG LYS D 190 7156 8832 4506 -652 167 612 C ATOM 1307 CD LYS D 190 -10.087 35.843 138.896 1.00 54.65 C ANISOU 1307 CD LYS D 190 7214 8912 4638 -820 314 632 C ATOM 1308 CE LYS D 190 -10.561 35.531 140.276 1.00 57.40 C ANISOU 1308 CE LYS D 190 7625 9409 4773 -790 457 690 C ATOM 1309 NZ LYS D 190 -12.032 35.577 140.334 1.00 60.17 N ANISOU 1309 NZ LYS D 190 7842 9819 5198 -937 617 719 N ATOM 1310 N PRO D 191 -5.423 34.815 137.253 1.00 55.30 N ANISOU 1310 N PRO D 191 7502 8737 4772 -291 59 946 N ATOM 1311 CA PRO D 191 -4.574 33.682 137.693 1.00 57.81 C ANISOU 1311 CA PRO D 191 7978 9045 4940 -74 145 1205 C ATOM 1312 C PRO D 191 -3.206 34.098 138.229 1.00 58.90 C ANISOU 1312 C PRO D 191 7890 9444 5042 122 -12 1310 C ATOM 1313 O PRO D 191 -2.769 33.566 139.247 1.00 61.29 O ANISOU 1313 O PRO D 191 8220 9914 5150 263 -27 1482 O ATOM 1314 CB PRO D 191 -4.415 32.806 136.439 1.00 58.44 C ANISOU 1314 CB PRO D 191 8314 8791 5099 -22 311 1321 C ATOM 1315 CG PRO D 191 -5.427 33.308 135.428 1.00 58.14 C ANISOU 1315 CG PRO D 191 8286 8596 5206 -287 288 1120 C ATOM 1316 CD PRO D 191 -5.837 34.701 135.830 1.00 55.80 C ANISOU 1316 CD PRO D 191 7664 8539 4997 -398 117 906 C ATOM 1317 N GLN D 192 -2.581 35.072 137.570 1.00 57.22 N ANISOU 1317 N GLN D 192 7445 9284 5009 102 -143 1221 N ATOM 1318 CA GLN D 192 -1.295 35.586 138.001 1.00 59.05 C ANISOU 1318 CA GLN D 192 7401 9798 5238 205 -333 1325 C ATOM 1319 C GLN D 192 -1.347 36.156 139.427 1.00 60.23 C ANISOU 1319 C GLN D 192 7468 10244 5173 98 -536 1229 C ATOM 1320 O GLN D 192 -0.548 35.783 140.293 1.00 61.46 O ANISOU 1320 O GLN D 192 7545 10648 5155 225 -648 1433 O ATOM 1321 CB GLN D 192 -0.819 36.660 137.060 1.00 57.78 C ANISOU 1321 CB GLN D 192 7024 9617 5312 117 -427 1208 C ATOM 1322 CG GLN D 192 0.601 37.083 137.319 1.00 61.10 C ANISOU 1322 CG GLN D 192 7120 10326 5769 187 -613 1375 C ATOM 1323 CD GLN D 192 1.035 38.193 136.398 1.00 62.56 C ANISOU 1323 CD GLN D 192 7102 10473 6193 58 -687 1260 C ATOM 1324 OE1 GLN D 192 0.243 38.736 135.617 1.00 59.71 O ANISOU 1324 OE1 GLN D 192 6859 9874 5954 -68 -614 1037 O ATOM 1325 NE2 GLN D 192 2.305 38.556 136.503 1.00 65.86 N ANISOU 1325 NE2 GLN D 192 7191 11151 6680 79 -842 1439 N ATOM 1326 N LEU D 193 -2.297 37.055 139.654 1.00 58.38 N ANISOU 1326 N LEU D 193 7274 9978 4930 -114 -571 934 N ATOM 1327 CA LEU D 193 -2.533 37.639 140.976 1.00 59.08 C ANISOU 1327 CA LEU D 193 7399 10275 4773 -219 -704 796 C ATOM 1328 C LEU D 193 -2.904 36.585 142.002 1.00 61.49 C ANISOU 1328 C LEU D 193 7900 10652 4810 -111 -599 951 C ATOM 1329 O LEU D 193 -2.414 36.645 143.175 1.00 66.40 O ANISOU 1329 O LEU D 193 8535 11532 5158 -95 -761 1005 O ATOM 1330 CB LEU D 193 -3.653 38.664 140.884 1.00 57.45 C ANISOU 1330 CB LEU D 193 7257 9945 4625 -390 -645 486 C ATOM 1331 CG LEU D 193 -4.263 39.302 142.125 1.00 58.65 C ANISOU 1331 CG LEU D 193 7556 10207 4519 -475 -660 298 C ATOM 1332 CD1 LEU D 193 -3.280 40.246 142.765 1.00 61.51 C ANISOU 1332 CD1 LEU D 193 7880 10757 4733 -594 -942 194 C ATOM 1333 CD2 LEU D 193 -5.530 40.048 141.762 1.00 57.83 C ANISOU 1333 CD2 LEU D 193 7502 9930 4539 -540 -485 80 C ATOM 1334 N ALA D 194 -3.761 35.638 141.612 1.00 59.18 N ANISOU 1334 N ALA D 194 7782 10139 4563 -67 -346 1027 N ATOM 1335 CA ALA D 194 -4.210 34.609 142.576 1.00 62.60 C ANISOU 1335 CA ALA D 194 8436 10601 4747 11 -204 1184 C ATOM 1336 C ALA D 194 -3.049 33.671 142.968 1.00 63.77 C ANISOU 1336 C ALA D 194 8602 10873 4754 260 -253 1514 C ATOM 1337 O ALA D 194 -2.987 33.183 144.108 1.00 65.05 O ANISOU 1337 O ALA D 194 8887 11195 4631 349 -260 1650 O ATOM 1338 CB ALA D 194 -5.381 33.826 142.014 1.00 61.77 C ANISOU 1338 CB ALA D 194 8513 10221 4737 -69 62 1201 C ATOM 1339 N ARG D 195 -2.129 33.427 142.027 1.00 63.70 N ANISOU 1339 N ARG D 195 8470 10798 4935 403 -265 1670 N ATOM 1340 CA ARG D 195 -0.908 32.668 142.329 1.00 66.55 C ANISOU 1340 CA ARG D 195 8766 11319 5199 700 -305 2031 C ATOM 1341 C ARG D 195 -0.028 33.418 143.336 1.00 68.67 C ANISOU 1341 C ARG D 195 8769 12026 5294 674 -653 2063 C ATOM 1342 O ARG D 195 0.371 32.863 144.366 1.00 73.91 O ANISOU 1342 O ARG D 195 9475 12916 5688 824 -728 2291 O ATOM 1343 CB ARG D 195 -0.131 32.340 141.060 1.00 66.05 C ANISOU 1343 CB ARG D 195 8615 11092 5387 885 -195 2199 C ATOM 1344 N TYR D 196 0.223 34.691 143.073 1.00 67.74 N ANISOU 1344 N TYR D 196 8416 12019 5301 451 -876 1830 N ATOM 1345 CA TYR D 196 1.035 35.499 143.966 1.00 71.07 C ANISOU 1345 CA TYR D 196 8626 12832 5546 324 -1244 1821 C ATOM 1346 C TYR D 196 0.465 35.597 145.360 1.00 72.67 C ANISOU 1346 C TYR D 196 9069 13177 5363 221 -1330 1705 C ATOM 1347 O TYR D 196 1.202 35.403 146.314 1.00 75.72 O ANISOU 1347 O TYR D 196 9393 13896 5478 277 -1563 1906 O ATOM 1348 CB TYR D 196 1.177 36.895 143.407 1.00 70.93 C ANISOU 1348 CB TYR D 196 8426 12803 5719 39 -1417 1531 C ATOM 1349 CG TYR D 196 2.026 37.838 144.235 1.00 74.73 C ANISOU 1349 CG TYR D 196 8726 13648 6018 -193 -1825 1484 C ATOM 1350 CD1 TYR D 196 3.419 37.642 144.369 1.00 78.50 C ANISOU 1350 CD1 TYR D 196 8834 14493 6497 -119 -2082 1831 C ATOM 1351 CD2 TYR D 196 1.450 38.956 144.860 1.00 74.98 C ANISOU 1351 CD2 TYR D 196 8961 13655 5871 -502 -1953 1107 C ATOM 1352 CE1 TYR D 196 4.202 38.532 145.096 1.00 81.21 C ANISOU 1352 CE1 TYR D 196 8998 15191 6665 -420 -2509 1792 C ATOM 1353 CE2 TYR D 196 2.226 39.840 145.601 1.00 78.83 C ANISOU 1353 CE2 TYR D 196 9367 14432 6152 -784 -2345 1034 C ATOM 1354 CZ TYR D 196 3.593 39.628 145.707 1.00 81.91 C ANISOU 1354 CZ TYR D 196 9371 15205 6545 -779 -2648 1371 C ATOM 1355 OH TYR D 196 4.329 40.522 146.426 1.00 87.88 O ANISOU 1355 OH TYR D 196 10046 16260 7084 -1139 -3079 1297 O ATOM 1356 N LEU D 197 -0.830 35.910 145.486 1.00 71.38 N ANISOU 1356 N LEU D 197 9169 12787 5163 82 -1143 1409 N ATOM 1357 CA LEU D 197 -1.489 35.964 146.830 1.00 73.20 C ANISOU 1357 CA LEU D 197 9683 13122 5006 21 -1139 1305 C ATOM 1358 C LEU D 197 -1.567 34.606 147.510 1.00 76.11 C ANISOU 1358 C LEU D 197 10234 13534 5150 262 -986 1620 C ATOM 1359 O LEU D 197 -1.485 34.519 148.745 1.00 79.43 O ANISOU 1359 O LEU D 197 10817 14177 5185 274 -1098 1676 O ATOM 1360 CB LEU D 197 -2.871 36.615 146.778 1.00 71.09 C ANISOU 1360 CB LEU D 197 9609 12619 4780 -131 -914 967 C ATOM 1361 CG LEU D 197 -2.791 38.136 146.620 1.00 71.02 C ANISOU 1361 CG LEU D 197 9547 12608 4830 -365 -1090 635 C ATOM 1362 CD1 LEU D 197 -4.171 38.692 146.340 1.00 68.74 C ANISOU 1362 CD1 LEU D 197 9396 12065 4657 -424 -806 374 C ATOM 1363 CD2 LEU D 197 -2.124 38.820 147.820 1.00 74.96 C ANISOU 1363 CD2 LEU D 197 10163 13381 4936 -514 -1408 547 C ATOM 1364 N GLY D 198 -1.686 33.552 146.707 1.00 75.54 N ANISOU 1364 N GLY D 198 10181 13229 5289 449 -731 1830 N ATOM 1365 CA GLY D 198 -1.510 32.190 147.194 1.00 78.13 C ANISOU 1365 CA GLY D 198 10688 13558 5438 718 -578 2191 C ATOM 1366 C GLY D 198 -2.689 31.726 148.015 1.00 79.53 C ANISOU 1366 C GLY D 198 11210 13623 5382 669 -334 2140 C ATOM 1367 O GLY D 198 -3.722 32.419 148.111 1.00 74.77 O ANISOU 1367 O GLY D 198 10678 12934 4794 449 -242 1837 O ATOM 1368 N ASN D 199 -2.506 30.561 148.637 1.00 83.12 N ANISOU 1368 N ASN D 199 11870 14092 5616 901 -209 2470 N ATOM 1369 CA ASN D 199 -3.502 29.986 149.509 1.00 86.40 C ANISOU 1369 CA ASN D 199 12624 14423 5781 878 40 2496 C ATOM 1370 C ASN D 199 -3.705 30.918 150.745 1.00 90.77 C ANISOU 1370 C ASN D 199 13237 15269 5980 746 -142 2296 C ATOM 1371 O ASN D 199 -4.614 30.691 151.560 1.00 93.74 O ANISOU 1371 O ASN D 199 13886 15608 6124 706 77 2270 O ATOM 1372 CB ASN D 199 -3.060 28.571 149.940 1.00 90.68 C ANISOU 1372 CB ASN D 199 13395 14924 6135 1190 190 2931 C ATOM 1373 N THR D 200 -2.817 31.920 150.899 1.00 90.26 N ANISOU 1373 N THR D 200 12953 15487 5851 672 -532 2178 N ATOM 1374 CA THR D 200 -3.044 33.099 151.747 1.00 91.20 C ANISOU 1374 CA THR D 200 13168 15788 5695 460 -714 1871 C ATOM 1375 C THR D 200 -4.484 33.696 151.660 1.00 87.25 C ANISOU 1375 C THR D 200 12823 15045 5282 290 -401 1538 C ATOM 1376 O THR D 200 -5.100 33.946 152.699 1.00 89.64 O ANISOU 1376 O THR D 200 13408 15408 5241 257 -293 1435 O ATOM 1377 CB THR D 200 -1.994 34.194 151.413 1.00 90.56 C ANISOU 1377 CB THR D 200 12793 15915 5699 302 -1141 1731 C ATOM 1378 N VAL D 201 -5.000 33.859 150.426 1.00 80.15 N ANISOU 1378 N VAL D 201 11738 13887 4824 213 -242 1417 N ATOM 1379 CA VAL D 201 -6.255 34.575 150.105 1.00 75.52 C ANISOU 1379 CA VAL D 201 11169 13115 4407 66 2 1134 C ATOM 1380 C VAL D 201 -7.066 33.881 148.987 1.00 72.60 C ANISOU 1380 C VAL D 201 10689 12470 4426 40 279 1213 C ATOM 1381 O VAL D 201 -6.509 33.512 147.937 1.00 67.05 O ANISOU 1381 O VAL D 201 9826 11654 3996 63 198 1307 O ATOM 1382 CB VAL D 201 -5.931 36.020 149.649 1.00 74.11 C ANISOU 1382 CB VAL D 201 10841 12953 4363 -83 -223 820 C ATOM 1383 CG1 VAL D 201 -7.202 36.795 149.303 1.00 73.16 C ANISOU 1383 CG1 VAL D 201 10727 12649 4421 -167 46 570 C ATOM 1384 CG2 VAL D 201 -5.106 36.761 150.699 1.00 78.13 C ANISOU 1384 CG2 VAL D 201 11499 13714 4471 -149 -542 715 C ATOM 1385 N ASP D 202 -8.385 33.780 149.169 1.00 71.68 N ANISOU 1385 N ASP D 202 10651 12252 4331 -28 601 1172 N ATOM 1386 CA ASP D 202 -9.274 33.140 148.183 1.00 70.43 C ANISOU 1386 CA ASP D 202 10391 11865 4503 -136 831 1251 C ATOM 1387 C ASP D 202 -10.061 34.144 147.315 1.00 67.89 C ANISOU 1387 C ASP D 202 9829 11471 4495 -272 870 1020 C ATOM 1388 O ASP D 202 -10.999 34.809 147.763 1.00 67.54 O ANISOU 1388 O ASP D 202 9764 11484 4412 -294 1051 903 O ATOM 1389 CB ASP D 202 -10.188 32.174 148.925 1.00 73.36 C ANISOU 1389 CB ASP D 202 10958 12204 4709 -152 1156 1449 C ATOM 1390 CG ASP D 202 -11.286 31.568 148.054 1.00 72.55 C ANISOU 1390 CG ASP D 202 10755 11900 4910 -356 1387 1530 C ATOM 1391 OD1 ASP D 202 -11.444 31.868 146.845 1.00 69.88 O ANISOU 1391 OD1 ASP D 202 10208 11443 4897 -483 1301 1432 O ATOM 1392 OD2 ASP D 202 -12.044 30.786 148.662 1.00 79.43 O ANISOU 1392 OD2 ASP D 202 11770 12747 5660 -414 1658 1707 O ATOM 1393 N LEU D 203 -9.692 34.220 146.039 1.00 66.05 N ANISOU 1393 N LEU D 203 9424 11104 4569 -332 729 986 N ATOM 1394 CA LEU D 203 -10.258 35.195 145.111 1.00 64.12 C ANISOU 1394 CA LEU D 203 8951 10795 4616 -433 714 793 C ATOM 1395 C LEU D 203 -11.190 34.559 144.080 1.00 62.92 C ANISOU 1395 C LEU D 203 8688 10481 4737 -604 851 895 C ATOM 1396 O LEU D 203 -11.360 35.095 142.973 1.00 60.31 O ANISOU 1396 O LEU D 203 8176 10068 4671 -684 764 797 O ATOM 1397 CB LEU D 203 -9.119 35.895 144.383 1.00 65.17 C ANISOU 1397 CB LEU D 203 8976 10908 4876 -401 429 670 C ATOM 1398 CG LEU D 203 -8.101 36.591 145.303 1.00 67.87 C ANISOU 1398 CG LEU D 203 9398 11432 4957 -320 216 570 C ATOM 1399 CD1 LEU D 203 -6.764 36.766 144.633 1.00 68.32 C ANISOU 1399 CD1 LEU D 203 9325 11501 5129 -300 -61 589 C ATOM 1400 CD2 LEU D 203 -8.648 37.935 145.772 1.00 69.83 C ANISOU 1400 CD2 LEU D 203 9679 11720 5133 -351 257 304 C ATOM 1401 N SER D 204 -11.797 33.422 144.418 1.00 63.13 N ANISOU 1401 N SER D 204 8842 10459 4685 -689 1049 1098 N ATOM 1402 CA SER D 204 -12.765 32.798 143.531 1.00 62.58 C ANISOU 1402 CA SER D 204 8689 10251 4834 -937 1156 1201 C ATOM 1403 C SER D 204 -13.729 33.830 143.004 1.00 61.09 C ANISOU 1403 C SER D 204 8176 10157 4876 -1024 1170 1080 C ATOM 1404 O SER D 204 -13.883 33.935 141.800 1.00 60.93 O ANISOU 1404 O SER D 204 8027 10035 5087 -1162 1049 1050 O ATOM 1405 CB SER D 204 -13.537 31.676 144.227 1.00 67.26 C ANISOU 1405 CB SER D 204 9436 10824 5294 -1066 1411 1424 C ATOM 1406 OG SER D 204 -12.650 30.672 144.673 1.00 70.21 O ANISOU 1406 OG SER D 204 10143 11081 5452 -950 1419 1570 O ATOM 1407 N SER D 205 -14.345 34.632 143.878 1.00 61.21 N ANISOU 1407 N SER D 205 8084 10361 4812 -911 1327 1019 N ATOM 1408 CA SER D 205 -15.407 35.558 143.466 1.00 61.05 C ANISOU 1408 CA SER D 205 7739 10446 5011 -934 1416 971 C ATOM 1409 C SER D 205 -14.911 36.971 143.149 1.00 59.20 C ANISOU 1409 C SER D 205 7437 10208 4846 -753 1275 727 C ATOM 1410 O SER D 205 -15.724 37.847 142.875 1.00 60.13 O ANISOU 1410 O SER D 205 7321 10400 5125 -697 1374 694 O ATOM 1411 CB SER D 205 -16.509 35.626 144.519 1.00 65.68 C ANISOU 1411 CB SER D 205 8242 11215 5496 -879 1756 1087 C ATOM 1412 OG SER D 205 -16.972 34.336 144.922 1.00 68.20 O ANISOU 1412 OG SER D 205 8644 11534 5735 -1066 1915 1326 O ATOM 1413 N PHE D 206 -13.597 37.201 143.208 1.00 58.04 N ANISOU 1413 N PHE D 206 7486 9984 4580 -662 1059 585 N ATOM 1414 CA PHE D 206 -13.007 38.506 142.916 1.00 57.46 C ANISOU 1414 CA PHE D 206 7392 9877 4561 -550 910 355 C ATOM 1415 C PHE D 206 -13.158 38.839 141.415 1.00 55.13 C ANISOU 1415 C PHE D 206 6877 9475 4594 -639 780 338 C ATOM 1416 O PHE D 206 -12.682 38.082 140.551 1.00 54.63 O ANISOU 1416 O PHE D 206 6826 9300 4628 -759 633 417 O ATOM 1417 CB PHE D 206 -11.523 38.509 143.302 1.00 57.48 C ANISOU 1417 CB PHE D 206 7602 9865 4370 -498 678 268 C ATOM 1418 CG PHE D 206 -10.854 39.866 143.191 1.00 58.06 C ANISOU 1418 CG PHE D 206 7697 9908 4454 -445 521 29 C ATOM 1419 CD1 PHE D 206 -11.240 40.937 144.014 1.00 62.23 C ANISOU 1419 CD1 PHE D 206 8358 10465 4820 -351 649 -146 C ATOM 1420 CD2 PHE D 206 -9.828 40.087 142.261 1.00 57.35 C ANISOU 1420 CD2 PHE D 206 7535 9732 4523 -495 272 -15 C ATOM 1421 CE1 PHE D 206 -10.616 42.188 143.909 1.00 61.79 C ANISOU 1421 CE1 PHE D 206 8395 10326 4754 -348 510 -378 C ATOM 1422 CE2 PHE D 206 -9.220 41.330 142.150 1.00 56.52 C ANISOU 1422 CE2 PHE D 206 7455 9582 4435 -497 134 -221 C ATOM 1423 CZ PHE D 206 -9.619 42.375 142.967 1.00 59.52 C ANISOU 1423 CZ PHE D 206 8000 9965 4649 -443 242 -410 C ATOM 1424 N ASP D 207 -13.820 39.949 141.108 1.00 55.49 N ANISOU 1424 N ASP D 207 6759 9539 4785 -556 855 250 N ATOM 1425 CA ASP D 207 -13.926 40.416 139.740 1.00 54.87 C ANISOU 1425 CA ASP D 207 6494 9371 4981 -608 720 232 C ATOM 1426 C ASP D 207 -12.674 41.248 139.360 1.00 54.09 C ANISOU 1426 C ASP D 207 6521 9136 4892 -547 516 33 C ATOM 1427 O ASP D 207 -12.502 42.390 139.815 1.00 57.05 O ANISOU 1427 O ASP D 207 6983 9487 5205 -419 557 -139 O ATOM 1428 CB ASP D 207 -15.205 41.211 139.538 1.00 57.78 C ANISOU 1428 CB ASP D 207 6605 9835 5512 -512 900 284 C ATOM 1429 CG ASP D 207 -15.446 41.574 138.069 1.00 57.35 C ANISOU 1429 CG ASP D 207 6341 9722 5728 -578 743 322 C ATOM 1430 OD1 ASP D 207 -16.549 41.406 137.583 1.00 63.61 O ANISOU 1430 OD1 ASP D 207 6850 10643 6675 -650 795 507 O ATOM 1431 OD2 ASP D 207 -14.538 42.030 137.400 1.00 56.92 O ANISOU 1431 OD2 ASP D 207 6391 9511 5722 -568 563 189 O ATOM 1432 N PHE D 208 -11.813 40.671 138.537 1.00 51.40 N ANISOU 1432 N PHE D 208 6215 8693 4620 -648 324 69 N ATOM 1433 CA PHE D 208 -10.516 41.289 138.204 1.00 50.96 C ANISOU 1433 CA PHE D 208 6237 8544 4581 -616 138 -62 C ATOM 1434 C PHE D 208 -10.732 42.680 137.583 1.00 50.92 C ANISOU 1434 C PHE D 208 6154 8450 4740 -557 132 -204 C ATOM 1435 O PHE D 208 -10.101 43.655 137.970 1.00 49.67 O ANISOU 1435 O PHE D 208 6103 8249 4520 -514 85 -372 O ATOM 1436 CB PHE D 208 -9.700 40.340 137.301 1.00 48.82 C ANISOU 1436 CB PHE D 208 5996 8173 4379 -689 9 57 C ATOM 1437 CG PHE D 208 -8.306 40.821 137.024 1.00 48.52 C ANISOU 1437 CG PHE D 208 5980 8088 4364 -652 -153 -9 C ATOM 1438 CD1 PHE D 208 -7.263 40.604 137.950 1.00 50.79 C ANISOU 1438 CD1 PHE D 208 6336 8491 4469 -613 -242 9 C ATOM 1439 CD2 PHE D 208 -8.033 41.561 135.865 1.00 46.10 C ANISOU 1439 CD2 PHE D 208 5602 7653 4261 -665 -224 -69 C ATOM 1440 CE1 PHE D 208 -5.979 41.076 137.699 1.00 50.55 C ANISOU 1440 CE1 PHE D 208 6251 8473 4483 -612 -408 -10 C ATOM 1441 CE2 PHE D 208 -6.748 42.037 135.628 1.00 46.87 C ANISOU 1441 CE2 PHE D 208 5683 7726 4399 -655 -353 -104 C ATOM 1442 CZ PHE D 208 -5.720 41.790 136.543 1.00 48.83 C ANISOU 1442 CZ PHE D 208 5948 8116 4488 -641 -450 -67 C ATOM 1443 N ARG D 209 -11.691 42.764 136.665 1.00 52.18 N ANISOU 1443 N ARG D 209 6145 8589 5092 -568 182 -120 N ATOM 1444 CA ARG D 209 -11.911 43.988 135.926 1.00 52.65 C ANISOU 1444 CA ARG D 209 6132 8552 5319 -481 181 -203 C ATOM 1445 C ARG D 209 -12.393 45.095 136.805 1.00 52.43 C ANISOU 1445 C ARG D 209 6169 8533 5218 -307 366 -326 C ATOM 1446 O ARG D 209 -11.905 46.178 136.677 1.00 53.56 O ANISOU 1446 O ARG D 209 6432 8531 5384 -246 346 -480 O ATOM 1447 CB ARG D 209 -12.929 43.787 134.779 1.00 52.58 C ANISOU 1447 CB ARG D 209 5904 8570 5504 -526 170 -39 C ATOM 1448 CG ARG D 209 -13.154 45.057 133.963 1.00 53.06 C ANISOU 1448 CG ARG D 209 5894 8533 5731 -395 170 -86 C ATOM 1449 CD ARG D 209 -13.667 44.777 132.554 1.00 51.62 C ANISOU 1449 CD ARG D 209 5553 8352 5705 -491 40 70 C ATOM 1450 NE ARG D 209 -12.606 44.308 131.643 1.00 49.13 N ANISOU 1450 NE ARG D 209 5397 7876 5393 -624 -136 41 N ATOM 1451 CZ ARG D 209 -11.692 45.083 131.020 1.00 48.22 C ANISOU 1451 CZ ARG D 209 5392 7584 5343 -566 -196 -59 C ATOM 1452 NH1 ARG D 209 -11.641 46.392 131.244 1.00 48.54 N ANISOU 1452 NH1 ARG D 209 5450 7551 5440 -408 -114 -173 N ATOM 1453 NH2 ARG D 209 -10.786 44.529 130.178 1.00 45.95 N ANISOU 1453 NH2 ARG D 209 5233 7170 5055 -664 -307 -39 N ATOM 1454 N THR D 210 -13.388 44.839 137.641 1.00 54.63 N ANISOU 1454 N THR D 210 6388 8957 5410 -226 576 -244 N ATOM 1455 CA THR D 210 -13.968 45.878 138.506 1.00 59.09 C ANISOU 1455 CA THR D 210 7062 9509 5880 -2 834 -342 C ATOM 1456 C THR D 210 -13.265 46.064 139.885 1.00 60.77 C ANISOU 1456 C THR D 210 7628 9693 5768 4 874 -533 C ATOM 1457 O THR D 210 -13.445 47.113 140.524 1.00 61.94 O ANISOU 1457 O THR D 210 8010 9734 5788 166 1059 -688 O ATOM 1458 CB THR D 210 -15.461 45.609 138.827 1.00 62.41 C ANISOU 1458 CB THR D 210 7235 10126 6352 128 1110 -129 C ATOM 1459 OG1 THR D 210 -15.585 44.399 139.601 1.00 63.61 O ANISOU 1459 OG1 THR D 210 7384 10433 6350 0 1147 -23 O ATOM 1460 CG2 THR D 210 -16.294 45.505 137.554 1.00 61.86 C ANISOU 1460 CG2 THR D 210 6788 10143 6572 100 1047 88 C ATOM 1461 N GLY D 211 -12.516 45.056 140.342 1.00 59.64 N ANISOU 1461 N GLY D 211 7554 9637 5469 -156 713 -509 N ATOM 1462 CA GLY D 211 -11.876 45.105 141.673 1.00 63.25 C ANISOU 1462 CA GLY D 211 8326 10125 5581 -172 704 -646 C ATOM 1463 C GLY D 211 -12.821 44.914 142.858 1.00 67.72 C ANISOU 1463 C GLY D 211 9002 10803 5925 -29 1013 -600 C ATOM 1464 O GLY D 211 -12.471 45.272 144.001 1.00 69.71 O ANISOU 1464 O GLY D 211 9597 11044 5844 -2 1058 -752 O ATOM 1465 N LYS D 212 -13.997 44.326 142.596 1.00 69.56 N ANISOU 1465 N LYS D 212 8954 11154 6321 34 1218 -376 N ATOM 1466 CA LYS D 212 -15.042 44.047 143.617 1.00 73.12 C ANISOU 1466 CA LYS D 212 9422 11745 6616 177 1570 -259 C ATOM 1467 C LYS D 212 -15.374 42.531 143.684 1.00 76.40 C ANISOU 1467 C LYS D 212 9650 12327 7050 16 1565 -5 C ATOM 1468 O LYS D 212 -15.195 41.804 142.686 1.00 76.36 O ANISOU 1468 O LYS D 212 9442 12316 7256 -169 1354 108 O ATOM 1469 CB LYS D 212 -16.312 44.813 143.240 1.00 73.43 C ANISOU 1469 CB LYS D 212 9225 11803 6871 404 1874 -158 C ATOM 1470 CG LYS D 212 -16.181 46.329 143.270 1.00 74.91 C ANISOU 1470 CG LYS D 212 9665 11776 7019 621 1986 -382 C ATOM 1471 N MET D 213 -15.894 42.055 144.823 1.00 80.93 N ANISOU 1471 N MET D 213 10334 13022 7393 84 1824 88 N ATOM 1472 CA MET D 213 -16.470 40.696 144.891 1.00 84.01 C ANISOU 1472 CA MET D 213 10541 13552 7827 -69 1902 362 C ATOM 1473 C MET D 213 -17.768 40.649 144.061 1.00 84.79 C ANISOU 1473 C MET D 213 10180 13765 8268 -106 2047 588 C ATOM 1474 O MET D 213 -18.614 41.533 144.208 1.00 86.14 O ANISOU 1474 O MET D 213 10209 14005 8513 120 2315 617 O ATOM 1475 CB MET D 213 -16.784 40.285 146.341 1.00 91.44 C ANISOU 1475 CB MET D 213 11714 14596 8430 26 2190 429 C ATOM 1476 CG MET D 213 -15.661 40.397 147.374 1.00 94.90 C ANISOU 1476 CG MET D 213 12619 14982 8455 74 2065 236 C ATOM 1477 SD MET D 213 -14.021 39.893 146.792 1.00 98.31 S ANISOU 1477 SD MET D 213 13142 15327 8881 -115 1553 155 S ATOM 1478 CE MET D 213 -14.198 38.101 146.738 1.00 97.32 C ANISOU 1478 CE MET D 213 12934 15256 8785 -275 1578 472 C ATOM 1479 N MET D 214 -17.913 39.645 143.186 1.00 83.60 N ANISOU 1479 N MET D 214 9816 13635 8311 -387 1868 760 N ATOM 1480 CA MET D 214 -19.179 39.414 142.424 1.00 86.28 C ANISOU 1480 CA MET D 214 9696 14138 8945 -523 1943 1020 C ATOM 1481 C MET D 214 -19.797 38.041 142.671 1.00 88.50 C ANISOU 1481 C MET D 214 9880 14529 9215 -812 2030 1284 C ATOM 1482 O MET D 214 -19.181 37.013 142.388 1.00 86.37 O ANISOU 1482 O MET D 214 9811 14120 8884 -1060 1833 1290 O ATOM 1483 CB MET D 214 -18.962 39.580 140.917 1.00 84.61 C ANISOU 1483 CB MET D 214 9319 13839 8987 -675 1616 992 C ATOM 1484 CG MET D 214 -18.884 41.026 140.466 1.00 85.94 C ANISOU 1484 CG MET D 214 9425 13955 9271 -405 1604 843 C ATOM 1485 SD MET D 214 -20.416 41.935 140.755 1.00 95.28 S ANISOU 1485 SD MET D 214 10206 15386 10609 -110 1990 1055 S ATOM 1486 CE MET D 214 -19.776 43.613 140.870 1.00 95.61 C ANISOU 1486 CE MET D 214 10545 15198 10583 285 2063 750 C TER 1487 MET D 214 HETATM 1488 S SO4 A 301 -9.295 36.080 100.486 1.00 51.90 S HETATM 1489 O1 SO4 A 301 -8.631 37.158 99.728 1.00 51.86 O HETATM 1490 O2 SO4 A 301 -8.792 34.754 100.113 1.00 47.45 O HETATM 1491 O3 SO4 A 301 -10.749 36.155 100.264 1.00 45.25 O HETATM 1492 O4 SO4 A 301 -9.015 36.336 101.937 1.00 54.57 O HETATM 1493 UNK UNX A 302 -8.053 17.131 114.884 1.00 55.17 X HETATM 1494 UNK UNX A 303 -6.080 21.395 121.373 1.00 46.03 X HETATM 1495 UNK UNX A 304 -14.392 25.388 127.489 1.00 40.87 X HETATM 1496 UNK UNX A 305 -13.821 32.838 97.753 1.00 46.01 X HETATM 1497 UNK UNX A 306 -6.154 29.081 114.360 1.00 51.79 X HETATM 1498 UNK UNX A 307 -24.409 24.733 110.219 1.00 37.58 X HETATM 1499 UNK UNX A 308 -25.590 31.849 101.829 1.00 45.42 X HETATM 1500 UNK UNX A 309 -17.904 26.698 119.804 1.00 41.68 X HETATM 1501 UNK UNX A 310 -8.011 36.521 110.226 1.00 48.11 X HETATM 1502 UNK UNX A 311 -13.484 30.644 119.125 1.00 41.13 X HETATM 1503 UNK UNX A 312 -6.777 20.059 118.858 1.00 37.83 X HETATM 1504 UNK UNX A 313 -9.756 30.866 118.201 1.00 35.35 X HETATM 1505 UNK UNX A 314 -9.951 37.232 118.803 1.00 35.49 X HETATM 1506 UNK UNX B 101 -19.364 27.173 117.466 1.00 48.74 X HETATM 1507 UNK UNX B 102 -13.402 38.979 119.315 1.00 45.16 X HETATM 1508 UNK UNX B 103 0.445 40.168 118.848 1.00 52.25 X HETATM 1509 UNK UNX C 101 -29.902 27.779 118.892 1.00 47.84 X HETATM 1510 UNK UNX C 102 -22.200 34.724 125.660 1.00 52.40 X HETATM 1511 UNK UNX C 103 -10.505 39.637 119.459 1.00 42.37 X HETATM 1512 UNK UNX C 104 -7.848 31.696 126.409 1.00 39.34 X HETATM 1513 UNK UNX C 105 -3.079 34.674 120.666 1.00 46.82 X HETATM 1514 C1 GOL C 106 -2.291 50.916 124.908 1.00 47.82 C HETATM 1515 O1 GOL C 106 -2.876 49.610 124.826 1.00 44.68 O HETATM 1516 C2 GOL C 106 -1.676 51.317 123.560 1.00 46.44 C HETATM 1517 O2 GOL C 106 -2.700 51.396 122.558 1.00 45.08 O HETATM 1518 C3 GOL C 106 -0.606 50.312 123.094 1.00 49.94 C HETATM 1519 O3 GOL C 106 0.471 50.156 124.055 1.00 51.66 O HETATM 1520 UNK UNX D 301 4.360 42.515 147.884 1.00 55.94 X HETATM 1521 UNK UNX D 302 -12.506 37.962 137.246 1.00 43.61 X HETATM 1522 UNK UNX D 303 -12.448 46.358 127.483 1.00 41.94 X HETATM 1523 O HOH A 401 -9.672 24.096 99.403 1.00 45.93 O HETATM 1524 O HOH A 402 -16.729 19.528 101.801 1.00 44.19 O HETATM 1525 O HOH A 403 -15.936 28.409 115.748 1.00 34.47 O HETATM 1526 O HOH A 404 -12.482 19.155 105.045 1.00 49.91 O HETATM 1527 O HOH A 405 -13.000 21.832 96.132 1.00 50.89 O HETATM 1528 O HOH A 406 -9.420 27.354 119.778 1.00 39.00 O HETATM 1529 O HOH A 407 -17.682 38.183 107.627 1.00 44.52 O HETATM 1530 O HOH A 408 -16.220 33.090 96.425 1.00 48.39 O HETATM 1531 O HOH A 409 -15.571 29.181 118.473 1.00 34.80 O HETATM 1532 O HOH A 410 -12.168 23.822 98.200 1.00 50.17 O HETATM 1533 O HOH A 411 -22.602 39.491 101.693 1.00 61.54 O HETATM 1534 O HOH A 412 -19.939 29.152 115.272 1.00 34.31 O HETATM 1535 O HOH A 413 -11.240 35.034 114.032 1.00 44.35 O HETATM 1536 O HOH A 414 -11.837 37.461 109.746 1.00 54.56 O HETATM 1537 O HOH A 415 -22.993 23.285 112.041 1.00 49.32 O HETATM 1538 O HOH A 416 -16.114 35.815 116.172 1.00 37.49 O HETATM 1539 O HOH B 201 -9.010 41.460 129.264 1.00 42.25 O HETATM 1540 O HOH B 202 -10.170 40.388 122.050 1.00 37.71 O HETATM 1541 O HOH B 203 -15.053 35.370 118.770 1.00 34.68 O HETATM 1542 O HOH B 204 -0.728 37.683 132.479 1.00 51.05 O HETATM 1543 O HOH B 205 -11.924 43.417 126.927 1.00 39.55 O HETATM 1544 O HOH B 206 -24.000 24.141 128.043 1.00 55.58 O HETATM 1545 O HOH B 207 -13.246 42.397 124.816 1.00 41.78 O HETATM 1546 O HOH B 208 -8.241 41.396 132.122 1.00 50.58 O HETATM 1547 O HOH B 209 -11.725 42.597 122.676 1.00 42.59 O HETATM 1548 O HOH C 201 -4.130 49.188 127.160 1.00 39.24 O HETATM 1549 O HOH C 202 -13.459 34.180 127.988 1.00 42.49 O HETATM 1550 O HOH C 203 -7.896 42.099 122.038 1.00 42.96 O HETATM 1551 O HOH C 204 0.145 48.195 126.041 1.00 45.49 O HETATM 1552 O HOH C 205 -7.390 42.706 118.984 1.00 45.66 O HETATM 1553 O HOH C 206 -15.135 35.800 129.360 1.00 49.30 O HETATM 1554 O HOH D 401 -1.864 48.852 128.402 1.00 47.45 O HETATM 1555 O HOH D 402 -1.748 52.243 120.115 1.00 50.37 O HETATM 1556 O HOH D 403 -4.484 43.085 131.978 1.00 44.79 O HETATM 1557 O HOH D 404 -3.586 42.897 129.503 1.00 38.55 O HETATM 1558 O HOH D 405 -7.385 42.785 127.806 1.00 42.24 O HETATM 1559 O HOH D 406 -13.240 48.356 132.533 1.00 53.32 O HETATM 1560 O HOH D 407 -9.342 44.284 126.399 1.00 40.69 O HETATM 1561 O HOH D 408 -1.303 44.027 129.009 1.00 54.01 O HETATM 1562 O HOH D 409 -6.989 43.477 131.234 1.00 47.66 O HETATM 1563 O HOH D 410 -9.211 43.941 123.644 1.00 38.70 O CONECT 598 628 CONECT 611 612 617 620 CONECT 612 611 613 618 CONECT 613 612 614 CONECT 614 613 615 619 CONECT 615 614 616 617 CONECT 616 615 CONECT 617 611 615 CONECT 618 612 CONECT 619 614 CONECT 620 611 621 624 CONECT 621 620 622 CONECT 622 621 623 625 CONECT 623 622 624 626 CONECT 624 620 623 CONECT 625 622 631 CONECT 626 623 627 CONECT 627 626 628 CONECT 628 598 627 629 630 CONECT 629 628 CONECT 630 628 CONECT 631 625 CONECT 1488 1489 1490 1491 1492 CONECT 1489 1488 CONECT 1490 1488 CONECT 1491 1488 CONECT 1492 1488 CONECT 1514 1515 1516 CONECT 1515 1514 CONECT 1516 1514 1517 1518 CONECT 1517 1516 CONECT 1518 1516 1519 CONECT 1519 1518 MASTER 417 0 27 4 12 0 4 6 1559 4 33 16 END
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Related entries of code: 6c1t
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code
Check Database
Protein Sequence Similarity
6c1v
RCSB PDB
PDBbind
12aa, >6C1V_2|Chains... at 100%
Complexes with the same small molecule ligand
PDB Code
Check Database
Ligand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID
6c1t
Complex Type
Protein-Nucleic Acid
PDBbind Subset
general set
Protein Name
Methyl-CpG-binding domain protein 2, MBD2
Ligand Name
methylated DNA (mCAC)
EC.Number
E.C.-.-.-.-
Resolution
1.84(Å)
Affinity (Kd/Ki/IC50)
Kd=3.2uM
Release Year
2018
Protein/NA Sequence
Check fasta file
Primary Reference
(2018) J. Biol. Chem. Vol. 293: pp. 7344-7354
Links to External Databases
RCSB PDB
The mother database
PDBsum
Enhanced annotations on PDB entries
Pubchem
Comprehensive collection of chemical and biological data
UniProtKB AC
UniProt accession number (AC):
Q9UBB5
Entrez Gene ID
NCBI Entrez Gene ID:
8932
ASD
Information of known allosteric effects of PDB entries
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