Browse entries in the PDBbind-CN Database

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Related entries of code: 6fyz
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2vqjRCSB PDB    PDBbind413aa, >2VQJ_1|Chain... *
2vqmRCSB PDB    PDBbind413aa, >2VQM_1|Chain... at 100%
4cbtRCSB PDB    PDBbind395aa, >4CBT_1|Chains... at 97%
4cbyRCSB PDB    PDBbind395aa, >4CBY_1|Chains... at 97%
5a2sRCSB PDB    PDBbind395aa, >5A2S_1|Chains... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6fyz
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameHistone deacetylase 4
Ligand NameEBE
EC.Number E.C.-.-.-.-
Resolution 2.15(Å)
Affinity (Kd/Ki/IC50)Kd=0.039uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Bioorg. Med. Chem. Lett. Vol. 29: pp. 83-88
Ligand Properties
Formula C19H16FN3O2
Molecular Weight 337.348
Exact Mass 337.123
No. of atoms 41
No. of bonds 43
Polar Surface Area 75.11
LOGP Value 2.75      (Computed with XLOGP3)
3.62      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 2
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 5
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P56524  
Entrez Gene IDNCBI Entrez Gene ID: 9759  
ASDInformation of known allosteric effects of PDB entries
 
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