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Related entries of code: 6g07
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5ntwRCSB PDB    PDBbind20aa, >5NTW_2|Chains... *
5nu1RCSB PDB    PDBbind20aa, >5NU1_2|Chains... at 100%
6fzuRCSB PDB    PDBbind20aa, >6FZU_2|Chains... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!

Entry Information
PDB ID6g07
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameNuclear receptor ROR-gamma
Ligand NameEEZ
EC.Number E.C.-.-.-.-
Resolution 1.66(Å)
Affinity (Kd/Ki/IC50)IC50=27uM
Release Year2018
Protein/NA SequenceCheck fasta file
Primary Reference (2018) J. Med. Chem. Vol. 61: pp. 6724-6735
Ligand Properties
Formula C23H23ClN2O4S
Molecular Weight 458.958
Exact Mass 458.107
No. of atoms 54
No. of bonds 56
Polar Surface Area 93.74
LOGP Value 4.06      (Computed with XLOGP3)
6.00      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 1
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 9
No. of Nitrogen and Oxygen Atoms: 6
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P48552  P51449  
Entrez Gene IDNCBI Entrez Gene ID: 8204  6097  
ASDInformation of known allosteric effects of PDB entries

 
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