Browse entries in the PDBbind-CN Database

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Related entries of code: 6g2b
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
6g2oRCSB PDB    PDBbind136aa, >6G2O_1|Chain... at 100%
6g2fRCSB PDB    PDBbind136aa, >6G2F_1|Chain... at 100%
6g2eRCSB PDB    PDBbind136aa, >6G2E_1|Chain... at 100%
6g2cRCSB PDB    PDBbind136aa, >6G2C_1|Chain... at 100%
6g29RCSB PDB    PDBbind136aa, >6G29_1|Chain... at 100%
6g27RCSB PDB    PDBbind136aa, >6G27_1|Chain... at 100%
6g25RCSB PDB    PDBbind136aa, >6G25_1|Chain... at 100%
6g24RCSB PDB    PDBbind136aa, >6G24_1|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6g2b
Complex TypeProtein-Ligand
PDBbind Subsetrefined set
Protein NameHistone-lysine N-methyltransferase NSD3
Ligand NameEH8
EC.Number E.C.2.1.1.43
Resolution 1.61(Å)
Affinity (Kd/Ki/IC50)Kd=160uM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Nat.Chem.Biol. Vol. 15: pp. 822-829
Ligand Properties
Formula C15H13N3
Molecular Weight 235.284
Exact Mass 235.111
No. of atoms 31
No. of bonds 33
Polar Surface Area 30.71
LOGP Value 2.27      (Computed with XLOGP3)
3.15      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 2
No. of Rotatable Bonds: 2
No. of Nitrogen and Oxygen Atoms: 3
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q9BZ95  
Entrez Gene IDNCBI Entrez Gene ID: 54904  
ASDInformation of known allosteric effects of PDB entries
 
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