Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 6iby
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
5ajvRCSB PDB    PDBbind520aa, >5AJV_1|Chain... *
5ajwRCSB PDB    PDBbind520aa, >5AJW_1|Chain... at 100%
5ajxRCSB PDB    PDBbind520aa, >5AJX_1|Chain... at 100%
5ajyRCSB PDB    PDBbind520aa, >5AJY_1|Chain... at 100%
5ajzRCSB PDB    PDBbind520aa, >5AJZ_1|Chain... at 100%
5ak0RCSB PDB    PDBbind520aa, >5AK0_1|Chain... at 100%
6etjRCSB PDB    PDBbind520aa, >6ETJ_1|Chain... at 100%
6hvhRCSB PDB    PDBbind520aa, >6HVH_1|Chain... at 100%
6hviRCSB PDB    PDBbind520aa, >6HVI_1|Chain... at 100%
6hvjRCSB PDB    PDBbind520aa, >6HVJ_1|Chain... at 100%
6ic0RCSB PDB    PDBbind428aa, >6IC0_1|Chain... at 100%
6ibzRCSB PDB    PDBbind431aa, >6IBZ_1|Chain... at 100%
6ibxRCSB PDB    PDBbind429aa, >6IBX_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6iby
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NamePFKFB3
Ligand NameHAT
EC.Number E.C.-.-.-.-
Resolution 2.51(Å)
Affinity (Kd/Ki/IC50)IC50=15nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Bioorg. Med. Chem. Lett. Vol. 29: pp. 646-653
Ligand Properties
Formula C28H28N7O
Molecular Weight 478.568
Exact Mass 478.236
No. of atoms 64
No. of bonds 69
Polar Surface Area 89.17
LOGP Value 3.45      (Computed with XLOGP3)
4.98      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 6
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q16875  
Entrez Gene IDNCBI Entrez Gene ID: 5209  
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2025    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com