Browse entries in the PDBbind-CN Database

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Related entries of code: 6j5l
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4pmmRCSB PDB    PDBbind291aa, >4PMM_1|Chain... at 98%
4pmpRCSB PDB    PDBbind291aa, >4PMP_1|Chain... at 98%
4pmsRCSB PDB    PDBbind291aa, >4PMS_1|Chain... at 98%
4pmtRCSB PDB    PDBbind291aa, >4PMT_1|Chain... at 98%
4yneRCSB PDB    PDBbind303aa, >4YNE_1|Chain... at 97%
4ypsRCSB PDB    PDBbind303aa, >4YPS_1|Chain... at 97%
5h3qRCSB PDB    PDBbind324aa, >5H3Q_1|Chain... *
5wr7RCSB PDB    PDBbind304aa, >5WR7_1|Chain... at 100%
6dkbRCSB PDB    PDBbind320aa, >6DKB_1|Chain... at 99%
6dkgRCSB PDB    PDBbind320aa, >6DKG_1|Chain... at 99%
6dkiRCSB PDB    PDBbind320aa, >6DKI_1|Chain... at 99%
6pl3RCSB PDB    PDBbind311aa, >6PL3_1|Chain... at 100%
6pl2RCSB PDB    PDBbind311aa, >6PL2_1|Chain... at 100%
6pl1RCSB PDB    PDBbind311aa, >6PL1_1|Chain... at 100%
6nssRCSB PDB    PDBbind311aa, >6NSS_1|Chain... at 100%
6nspRCSB PDB    PDBbind297aa, >6NSP_1|Chain... at 100%
6nptRCSB PDB    PDBbind305aa, >6NPT_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
No complexes with the same small molecule ligand are found!
Entry Information
PDB ID6j5l
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameTrkA
Ligand NameB9C
EC.Number E.C.-.-.-.-
Resolution 2.3(Å)
Affinity (Kd/Ki/IC50)IC50=1.6nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Bioorg.Med.Chem.Lett. Vol. 29: pp. 2320-2326
Ligand Properties
Formula C24H28N7O2S
Molecular Weight 478.590
Exact Mass 478.203
No. of atoms 62
No. of bonds 66
Polar Surface Area 128
LOGP Value 2.39      (Computed with XLOGP3)
4.85      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 4
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 9
No. of Rings: 5
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P04629  
Entrez Gene IDNCBI Entrez Gene ID: 4914  
ASDInformation of known allosteric effects of PDB entries
 
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