Browse entries in the PDBbind-CN Database

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Related entries of code: 6m88
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
6m8dRCSB PDB    PDBbind261aa, >6M8D_1|Chain... at 100%
6m8cRCSB PDB    PDBbind261aa, >6M8C_1|Chain... at 100%
6m8bRCSB PDB    PDBbind261aa, >6M8B_1|Chain... at 100%
6m8aRCSB PDB    PDBbind261aa, >6M8A_1|Chain... at 100%
6m89RCSB PDB    PDBbind261aa, >6M89_1|Chain... at 100%
6m8eRCSB PDB    PDBbind261aa, >6M8E_1|Chain... at 100%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2o63RCSB PDB    PDBbindMYC
4gqrRCSB PDB    PDBbindMYC
5yunRCSB PDB    PDBbindMYC
Entry Information
PDB ID6m88
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameInositol polyphosphate multikinase
Ligand NameMYC
EC.Number E.C.2.7.1.151;2.7.1.140 ;2.7.1.153
Resolution 1.9(Å)
Affinity (Kd/Ki/IC50)IC50=1.1uM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) J. Med. Chem. Vol. 62: pp. 1443-1454
Ligand Properties
Formula C15H12O8
Molecular Weight 320.251
Exact Mass 320.053
No. of atoms 35
No. of bonds 37
Polar Surface Area 147.68
LOGP Value 1.13      (Computed with XLOGP3)
0.89      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 6
No. of Hydrogen Bond Acceptors: 7
No. of Rotatable Bonds: 7
No. of Nitrogen and Oxygen Atoms: 8
No. of Rings: 3
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q8NFU5  
Entrez Gene IDNCBI Entrez Gene ID: 253430  
ASDInformation of known allosteric effects of PDB entries
 
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