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Related entries of code: 6sdc
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
1r0pRCSB PDB    PDBbind312aa, >1R0P_1|Chain... at 100%
2rfnRCSB PDB    PDBbind310aa, >2RFN_1|Chains... at 96%
2wd1RCSB PDB    PDBbind292aa, >2WD1_1|Chain... at 98%
2wgjRCSB PDB    PDBbind306aa, >2WGJ_1|Chain... at 96%
3a4pRCSB PDB    PDBbind319aa, >3A4P_1|Chain... at 98%
3c1xRCSB PDB    PDBbind373aa, >3C1X_1|Chain... *
3ccnRCSB PDB    PDBbind310aa, >3CCN_1|Chain... at 96%
3cd8RCSB PDB    PDBbind310aa, >3CD8_1|Chain... at 96%
3ce3RCSB PDB    PDBbind314aa, >3CE3_1|Chain... at 100%
3cthRCSB PDB    PDBbind314aa, >3CTH_1|Chain... at 100%
3ctjRCSB PDB    PDBbind314aa, >3CTJ_1|Chain... at 100%
3dkfRCSB PDB    PDBbind317aa, >3DKF_1|Chain... at 98%
3dkgRCSB PDB    PDBbind317aa, >3DKG_1|Chain... at 98%
3efjRCSB PDB    PDBbind310aa, >3EFJ_1|Chains... at 96%
3efkRCSB PDB    PDBbind310aa, >3EFK_1|Chains... at 96%
3f66RCSB PDB    PDBbind298aa, >3F66_1|Chains... at 98%
3f82RCSB PDB    PDBbind314aa, >3F82_1|Chain... at 100%
3i5nRCSB PDB    PDBbind309aa, >3I5N_1|Chain... at 97%
3l8vRCSB PDB    PDBbind314aa, >3L8V_1|Chain... at 100%
3lq8RCSB PDB    PDBbind302aa, >3LQ8_1|Chain... at 97%
3q6wRCSB PDB    PDBbind307aa, >3Q6W_1|Chain... at 97%
3qtiRCSB PDB    PDBbind314aa, >3QTI_1|Chains... at 99%
3r7oRCSB PDB    PDBbind307aa, >3R7O_1|Chain... at 97%
3rhkRCSB PDB    PDBbind318aa, >3RHK_1|Chains... at 92%
3u6hRCSB PDB    PDBbind309aa, >3U6H_1|Chain... at 97%
3u6iRCSB PDB    PDBbind309aa, >3U6I_1|Chain... at 97%
3zbxRCSB PDB    PDBbind306aa, >3ZBX_1|Chain... at 96%
3zc5RCSB PDB    PDBbind306aa, >3ZC5_1|Chain... at 96%
3zclRCSB PDB    PDBbind306aa, >3ZCL_1|Chain... at 96%
3zxzRCSB PDB    PDBbind306aa, >3ZXZ_1|Chain... at 96%
3zzeRCSB PDB    PDBbind306aa, >3ZZE_1|Chain... at 96%
4aoiRCSB PDB    PDBbind306aa, >4AOI_1|Chain... at 96%
4ap7RCSB PDB    PDBbind306aa, >4AP7_1|Chain... at 96%
4degRCSB PDB    PDBbind309aa, >4DEG_1|Chain... at 97%
4dehRCSB PDB    PDBbind309aa, >4DEH_1|Chain... at 97%
4deiRCSB PDB    PDBbind309aa, >4DEI_1|Chain... at 97%
4eevRCSB PDB    PDBbind317aa, >4EEV_1|Chain... at 93%
4gg5RCSB PDB    PDBbind319aa, >4GG5_1|Chain... at 92%
4gg7RCSB PDB    PDBbind319aa, >4GG7_1|Chain... at 92%
4iwdRCSB PDB    PDBbind306aa, >4IWD_1|Chain... at 97%
4knbRCSB PDB    PDBbind287aa, >4KNB_1|Chains... at 98%
4mxcRCSB PDB    PDBbind319aa, >4MXC_1|Chain... at 92%
4r1vRCSB PDB    PDBbind291aa, >4R1V_1|Chain... at 98%
4r1yRCSB PDB    PDBbind292aa, >4R1Y_1|Chain... at 98%
4xmoRCSB PDB    PDBbind309aa, >4XMO_1|Chain... at 97%
4xyfRCSB PDB    PDBbind309aa, >4XYF_1|Chain... at 97%
5eobRCSB PDB    PDBbind319aa, >5EOB_1|Chain... at 92%
5eycRCSB PDB    PDBbind309aa, >5EYC_1|Chain... at 97%
5eydRCSB PDB    PDBbind309aa, >5EYD_1|Chain... at 97%
5hlwRCSB PDB    PDBbind299aa, >5HLW_1|Chain... at 98%
5ho6RCSB PDB    PDBbind312aa, >5HO6_1|Chain... at 100%
5hoaRCSB PDB    PDBbind312aa, >5HOA_1|Chain... at 99%
5horRCSB PDB    PDBbind312aa, >5HOR_1|Chain... at 99%
5ya5RCSB PDB    PDBbind319aa, >5YA5_1|Chain... at 92%
6sd9RCSB PDB    PDBbind309aa, >6SD9_1|Chain... at 95%
6sddRCSB PDB    PDBbind309aa, >6SDD_1|Chain... at 95%
6sdeRCSB PDB    PDBbind309aa, >6SDE_1|Chain... at 95%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
3lq8RCSB PDB    PDBbind88Z
5ia4RCSB PDB    PDBbind88Z
6sd9RCSB PDB    PDBbind88Z
Entry Information
PDB ID6sdc
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameD1228V cMET
Ligand Name88Z
EC.Number E.C.2.7.10.1
Resolution 1.67(Å)
Affinity (Kd/Ki/IC50)Kd=1.26nM
Release Year2019
Protein/NA SequenceCheck fasta file
Primary Reference (2019) Acs Med.Chem.Lett. Vol. 10: pp. 1322-1327
Ligand Properties
Formula C34H33F2N4O6
Molecular Weight 631.646
Exact Mass 631.237
No. of atoms 79
No. of bonds 84
Polar Surface Area 112.45
LOGP Value 5.59      (Computed with XLOGP3)
5.85      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 3
No. of Hydrogen Bond Acceptors: 3
No. of Rotatable Bonds: 14
No. of Nitrogen and Oxygen Atoms: 10
No. of Rings: 6
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P08581  
Entrez Gene IDNCBI Entrez Gene ID: 4233  
ASDInformation of known allosteric effects of PDB entries
 
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