Browse entries in the PDBbind-CN Database

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Related entries of code: 1t5a
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
4b2dRCSB PDB    PDBbind548aa, >4B2D_1|Chains... at 98%
4fxfRCSB PDB    PDBbind551aa, >4FXF_1|Chains... at 98%
4fxjRCSB PDB    PDBbind551aa, >4FXJ_1|Chains... at 98%
6b6uRCSB PDB    PDBbind525aa, >6B6U_1|Chains... at 99%
6gg4RCSB PDB    PDBbind551aa, >6GG4_1|Chains... at 97%
6gg5RCSB PDB    PDBbind551aa, >6GG5_1|Chains... at 97%
6nu5RCSB PDB    PDBbind551aa, >6NU5_1|Chains... at 97%
6nu1RCSB PDB    PDBbind551aa, >6NU1_1|Chains... at 97%
6gg3RCSB PDB    PDBbind551aa, >6GG3_1|Chains... at 97%
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
2duaRCSB PDB    PDBbindOXL
2hwgRCSB PDB    PDBbindOXL
2rk7RCSB PDB    PDBbindOXL
3mofRCSB PDB    PDBbindOXL
Entry Information
PDB ID1t5a
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein Namepyruvate kinase, m2 isozyme
Ligand NameOXL
EC.Number E.C.2.7.1.40
Resolution 2.8(Å)
Affinity (Kd/Ki/IC50)Ki=24uM
Release Year2005
Protein/NA SequenceCheck fasta file
Primary Reference Biochemistry v44 pp. 9417-29, 2005
Ligand Properties
Formula C2H2O4
Molecular Weight 90.035
Exact Mass 89.995
No. of atoms 8
No. of bonds 7
Polar Surface Area 74.6
LOGP Value 1.52      (Computed with XLOGP3)
-0.84      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 0
No. of Hydrogen Bond Acceptors: 4
No. of Rotatable Bonds: 0
No. of Nitrogen and Oxygen Atoms: 4
No. of Rings: 0
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): P14618  
Entrez Gene IDNCBI Entrez Gene ID: 5315  
ASDInformation of known allosteric effects of PDB entries
 
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