Browse entries in the PDBbind-CN Database

Display Options: Structure:  




Goto PDB code:

3D presentation of molecule is powered by 3Dmol, which supports all modern browsers and mobile devices via WebGL.

           
Hold mouse button: left to rotate,middle to shift,right to zoom

Related entries of code: 2xs0
Entries with 90% protein sequence similarity cutoff in PDBbind
PDB CodeCheck DatabaseProtein Sequence Similarity
2xrwRCSB PDB    PDBbind14aa, >2XRW_2|Chain... *
Complexes with the same small molecule ligand
PDB CodeCheck DatabaseLigand Name
1azgRCSB PDB    PDBbind14-mer
1bt6RCSB PDB    PDBbind14-mer
1eojRCSB PDB    PDBbind14-mer
1f3jRCSB PDB    PDBbind14-mer
1i3zRCSB PDB    PDBbind14-mer
1ihtRCSB PDB    PDBbind14-mer
1jbdRCSB PDB    PDBbind14-mer
1mv0RCSB PDB    PDBbind14-mer
1n5zRCSB PDB    PDBbind14-mer
1ntvRCSB PDB    PDBbind14-mer
1oj5RCSB PDB    PDBbind14-mer
1oxgRCSB PDB    PDBbind14-mer
1sfiRCSB PDB    PDBbind14-mer
1t29RCSB PDB    PDBbind14-mer
1x11RCSB PDB    PDBbind14-mer
1xh3RCSB PDB    PDBbind14-mer
1xn3RCSB PDB    PDBbind14-mer
1y19RCSB PDB    PDBbind14-mer
2fciRCSB PDB    PDBbind14-mer
2fx9RCSB PDB    PDBbind14-mer
2hugRCSB PDB    PDBbind14-mer
2jnwRCSB PDB    PDBbind14-mer
2l0iRCSB PDB    PDBbind14-mer
2l6eRCSB PDB    PDBbind14-mer
2l75RCSB PDB    PDBbind14-mer
2lo6RCSB PDB    PDBbind14-mer
2lozRCSB PDB    PDBbind14-mer
2ltwRCSB PDB    PDBbind14-mer
2n8tRCSB PDB    PDBbind14-mer
2oi3RCSB PDB    PDBbind14-mer
2w2uRCSB PDB    PDBbind14-mer
2xl2RCSB PDB    PDBbind14-mer
2xl3RCSB PDB    PDBbind14-mer
2xrwRCSB PDB    PDBbind14-mer
2y8oRCSB PDB    PDBbind14-mer
3d9kRCSB PDB    PDBbind14-mer
3d9lRCSB PDB    PDBbind14-mer
3d9mRCSB PDB    PDBbind14-mer
3d9nRCSB PDB    PDBbind14-mer
3d9oRCSB PDB    PDBbind14-mer
3d9pRCSB PDB    PDBbind14-mer
3g2wRCSB PDB    PDBbind14-mer
3lrhRCSB PDB    PDBbind14-mer
3meuRCSB PDB    PDBbind14-mer
3pknRCSB PDB    PDBbind14-mer
3rqeRCSB PDB    PDBbind14-mer
3so6RCSB PDB    PDBbind14-mer
3ualRCSB PDB    PDBbind14-mer
3wdzRCSB PDB    PDBbind14-mer
3wutRCSB PDB    PDBbind14-mer
3wuuRCSB PDB    PDBbind14-mer
3wuvRCSB PDB    PDBbind14-mer
4azaRCSB PDB    PDBbind14-mer
4ch2RCSB PDB    PDBbind14-mer
4ch8RCSB PDB    PDBbind14-mer
4erqRCSB PDB    PDBbind14-mer
4eryRCSB PDB    PDBbind14-mer
4erzRCSB PDB    PDBbind14-mer
4es0RCSB PDB    PDBbind14-mer
4ewrRCSB PDB    PDBbind14-mer
4fi9RCSB PDB    PDBbind14-mer
4glyRCSB PDB    PDBbind14-mer
4gxlRCSB PDB    PDBbind14-mer
4hgcRCSB PDB    PDBbind14-mer
4i7bRCSB PDB    PDBbind14-mer
4i7cRCSB PDB    PDBbind14-mer
4i7dRCSB PDB    PDBbind14-mer
4k1eRCSB PDB    PDBbind14-mer
4ktuRCSB PDB    PDBbind14-mer
4m1dRCSB PDB    PDBbind14-mer
4mnvRCSB PDB    PDBbind14-mer
4mnwRCSB PDB    PDBbind14-mer
4mnxRCSB PDB    PDBbind14-mer
4mnyRCSB PDB    PDBbind14-mer
4o4yRCSB PDB    PDBbind14-mer
4ofbRCSB PDB    PDBbind14-mer
4os2RCSB PDB    PDBbind14-mer
4os6RCSB PDB    PDBbind14-mer
4ov5RCSB PDB    PDBbind14-mer
4wv6RCSB PDB    PDBbind14-mer
5aerRCSB PDB    PDBbind14-mer
5dpwRCSB PDB    PDBbind14-mer
5e0lRCSB PDB    PDBbind14-mer
5eocRCSB PDB    PDBbind14-mer
5h5sRCSB PDB    PDBbind14-mer
5ixfRCSB PDB    PDBbind14-mer
5ly1RCSB PDB    PDBbind14-mer
5ly2RCSB PDB    PDBbind14-mer
5n8wRCSB PDB    PDBbind14-mer
5unjRCSB PDB    PDBbind14-mer
5vlhRCSB PDB    PDBbind14-mer
5vllRCSB PDB    PDBbind14-mer
5wbkRCSB PDB    PDBbind14-mer
5zooRCSB PDB    PDBbind14-mer
6axkRCSB PDB    PDBbind14-mer
6axlRCSB PDB    PDBbind14-mer
6b27RCSB PDB    PDBbind14-mer
6co4RCSB PDB    PDBbind14-mer
6qcgRCSB PDB    PDBbind14-mer
6qc0RCSB PDB    PDBbind14-mer
6pxcRCSB PDB    PDBbind14-mer
6o3wRCSB PDB    PDBbind14-mer
6o21RCSB PDB    PDBbind14-mer
6nk1RCSB PDB    PDBbind14-mer
6fzpRCSB PDB    PDBbind14-mer
6fzjRCSB PDB    PDBbind14-mer
6fzfRCSB PDB    PDBbind14-mer
6d3xRCSB PDB    PDBbind14-mer
6bvhRCSB PDB    PDBbind14-mer
6bcrRCSB PDB    PDBbind14-mer
5zk7RCSB PDB    PDBbind14-mer
5zjyRCSB PDB    PDBbind14-mer
5y21RCSB PDB    PDBbind14-mer
5xvwRCSB PDB    PDBbind14-mer
5vk0RCSB PDB    PDBbind14-mer
5ok6RCSB PDB    PDBbind14-mer
6bd1RCSB PDB    PDBbind14-mer
Entry Information
PDB ID2xs0
Complex TypeProtein-Ligand
PDBbind Subsetgeneral set
Protein NameMITOGEN-ACTIVATED PROTEIN KINASE 8
Ligand Name14-mer
EC.Number E.C.2.7.11.24
Resolution 2.6(Å)
Affinity (Kd/Ki/IC50)Kd=7.1uM
Release Year2011
Protein/NA SequenceCheck fasta file
Primary Reference (2012) Sci. Signal Vol. 5: pp. 74
Ligand Properties
Formula C67H109N20O19
Molecular Weight 1498.700
Exact Mass 1497.820
No. of atoms 215
No. of bonds 218
Polar Surface Area 643.22
LOGP Value 2.94      (Computed with XLOGP3)
-3.13      (Computed with Open Babel)
Drug likeness No. of Hydrogen Bond Donors: 13
No. of Hydrogen Bond Acceptors: 20
No. of Rotatable Bonds: 55
No. of Nitrogen and Oxygen Atoms: 39
No. of Rings: 4
Canonical SMILES
InChI String

Links to External Databases
RCSB PDBThe mother database
PDBsumEnhanced annotations on PDB entries
PubchemComprehensive collection of chemical and biological data
UniProtKB ACUniProt accession number (AC): Q12968  P45983  
Entrez Gene IDNCBI Entrez Gene ID: 4775  5599  
ASDInformation of known allosteric effects of PDB entries
 
This site has been visited times since Nov 2007.


Copyright ©2007-2025    涓婃捣鐩堣禌鎬濅俊鎭鎶鏈夐檺鍏徃    缃戠珯澶囨鍙凤細娌狪CP澶2021015625鍙-3    娌叕缃戝畨澶囷細姝ｅ湪鐢宠涓


Technical Support锛堟妧鏈敮鎸侊級: yingsaisi@foxmail.com