Welcome to PDBbind-CN database

Browse entries in the PDBbind-CN Database

HEADER    DNA/RNA BINDING PROTEIN                 09-MAY-08   3D2W              
TITLE     CRYSTAL STRUCTURE OF MOUSE TDP-43 RRM2 DOMAIN IN COMPLEX WITH DNA     
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: TAR DNA-BINDING PROTEIN 43;                                
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: RRM2 MOTIF, UNP RESIDUES 192-265;                          
COMPND   5 SYNONYM: TDP-43, RRM2 DOMAIN OF MOUSE TDP-43;                        
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: DNA (5'-D(*DGP*DTP*DTP*DGP*DAP*DGP*DCP*DGP*DTP*DT)-3');    
COMPND   9 CHAIN: B;                                                            
COMPND  10 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: MUS MUSCULUS;                                   
SOURCE   3 ORGANISM_COMMON: MOUSE;                                              
SOURCE   4 ORGANISM_TAXID: 10090;                                               
SOURCE   5 GENE: TARDBP, TDP43;                                                 
SOURCE   6 EXPRESSION_SYSTEM: ESCHERICHIA COLI;                                 
SOURCE   7 EXPRESSION_SYSTEM_TAXID: 562;                                        
SOURCE   8 EXPRESSION_SYSTEM_STRAIN: M15;                                       
SOURCE   9 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;                              
SOURCE  10 EXPRESSION_SYSTEM_PLASMID: PQE30;                                    
SOURCE  11 MOL_ID: 2;                                                           
SOURCE  12 SYNTHETIC: YES;                                                      
SOURCE  13 OTHER_DETAILS: NUCLEOTIDE SYNTHESIS                                  
KEYWDS    DP-43 PROTEINOPATHY, TDP-43 INCLUSIONS, RNA RECOGNITION MOTIF, FTLD-  
KEYWDS   2 U, ALS, RRM, DNA-RNA BINDING PROTEIN COMPLEX                         
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    P.H.KUO,H.S.YUAN                                                      
REVDAT   4   12-MAY-10 3D2W    1       REMARK                                   
REVDAT   3   14-APR-10 3D2W    1       REMARK                                   
REVDAT   2   21-APR-09 3D2W    1       JRNL                                     
REVDAT   1   07-APR-09 3D2W    0                                                
JRNL        AUTH   P.H.KUO,L.G.DOUDEVA,Y.T.WANG,C.K.SHEN,H.S.YUAN               
JRNL        TITL   STRUCTURAL INSIGHTS INTO TDP-43 IN NUCLEIC-ACID BINDING AND  
JRNL        TITL 2 DOMAIN INTERACTIONS                                          
JRNL        REF    NUCLEIC ACIDS RES.            V.  37  1799 2009              
JRNL        REFN                   ISSN 0305-1048                               
JRNL        PMID   19174564                                                     
JRNL        DOI    10.1093/NAR/GKP013                                           
REMARK   2                                                                      
REMARK   2 RESOLUTION.    1.65 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.2.0019                                      
REMARK   3   AUTHORS     : MURSHUDOV,VAGIN,DODSON                               
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.65                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 25.46                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.000                          
REMARK   3   COMPLETENESS FOR RANGE        (%) : 98.7                           
REMARK   3   NUMBER OF REFLECTIONS             : 12633                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.210                           
REMARK   3   R VALUE            (WORKING SET) : 0.207                           
REMARK   3   FREE R VALUE                     : 0.245                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 7.600                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 1041                            
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 1.65                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 1.69                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 892                          
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 95.99                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.2470                       
REMARK   3   BIN FREE R VALUE SET COUNT          : 66                           
REMARK   3   BIN FREE R VALUE                    : 0.2970                       
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 561                                     
REMARK   3   NUCLEIC ACID ATOMS       : 186                                     
REMARK   3   HETEROGEN ATOMS          : 5                                       
REMARK   3   SOLVENT ATOMS            : 116                                     
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : 28.20                          
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 23.14                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : -0.04000                                             
REMARK   3    B22 (A**2) : -0.03000                                             
REMARK   3    B33 (A**2) : 0.07000                                              
REMARK   3    B12 (A**2) : 0.00000                                              
REMARK   3    B13 (A**2) : 0.00000                                              
REMARK   3    B23 (A**2) : 0.00000                                              
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): 0.109         
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.109         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): 0.067         
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 1.912         
REMARK   3                                                                      
REMARK   3 CORRELATION COEFFICIENTS.                                            
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.949                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.931                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):   783 ; 0.009 ; 0.022       
REMARK   3   BOND LENGTHS OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  1095 ; 1.257 ; 2.253       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):    71 ; 4.855 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):    28 ;37.762 ;25.000       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):    95 ;14.735 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):     2 ;21.406 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   122 ; 0.076 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):   528 ; 0.005 ; 0.020       
REMARK   3   GENERAL PLANES OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):   331 ; 0.187 ; 0.200       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):   517 ; 0.309 ; 0.200       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):    69 ; 0.132 ; 0.200       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):    65 ; 0.183 ; 0.200       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):    39 ; 0.152 ; 0.200       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):   363 ; 0.839 ; 1.500       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):   574 ; 1.484 ; 2.000       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):   527 ; 1.676 ; 3.000       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):   521 ; 2.567 ; 4.500       
REMARK   3                                                                      
REMARK   3 ANISOTROPIC THERMAL FACTOR RESTRAINTS.    COUNT   RMS   WEIGHT       
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : NULL                                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : MASK                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.20                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING   
REMARK   3  POSITIONS                                                           
REMARK   4                                                                      
REMARK   4 3D2W COMPLIES WITH FORMAT V. 3.20, 01-DEC-08                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 15-MAY-08.                  
REMARK 100 THE RCSB ID CODE IS RCSB047523.                                      
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 23-JAN-08                          
REMARK 200  TEMPERATURE           (KELVIN) : 123                                
REMARK 200  PH                             : 4.2                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : NSRRC                              
REMARK 200  BEAMLINE                       : BL13C1                             
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 1                                  
REMARK 200  MONOCHROMATOR                  : SI(111)                            
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : ADSC QUANTUM 210                   
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : HKL-2000                           
REMARK 200  DATA SCALING SOFTWARE          : HKL-2000                           
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 13854                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.650                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 25.460                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 0.000                              
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 98.7                               
REMARK 200  DATA REDUNDANCY                : 4.700                              
REMARK 200  R MERGE                    (I) : 0.05800                            
REMARK 200  R SYM                      (I) : 0.05800                            
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 14.0000                            
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.65                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 1.71                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 97.0                               
REMARK 200  DATA REDUNDANCY IN SHELL       : 4.50                               
REMARK 200  R MERGE FOR SHELL          (I) : 0.32000                            
REMARK 200  R SYM FOR SHELL            (I) : 0.32000                            
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 3.510                              
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: CCP4                                                  
REMARK 200 STARTING MODEL: PDB ENTRY 1WF0                                       
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 42.54                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.14                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: RESERVOIR SOLUTION CONTAINING 2M (NH4)   
REMARK 280  2SO4, 0.1M PHOSPHATE-CITRATE, THE RESERVOIR SOLUTION CONTAINED AN   
REMARK 280  ADDITION OF 10% GLYCEROL, PH4.2, VAPOR DIFFUSION, HANGING DROP,     
REMARK 280  TEMPERATURE 298K                                                    
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: F 2 2 2                          
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,-Y,Z                                                 
REMARK 290       3555   -X,Y,-Z                                                 
REMARK 290       4555   X,-Y,-Z                                                 
REMARK 290       5555   X,Y+1/2,Z+1/2                                           
REMARK 290       6555   -X,-Y+1/2,Z+1/2                                         
REMARK 290       7555   -X,Y+1/2,-Z+1/2                                         
REMARK 290       8555   X,-Y+1/2,-Z+1/2                                         
REMARK 290       9555   X+1/2,Y,Z+1/2                                           
REMARK 290      10555   -X+1/2,-Y,Z+1/2                                         
REMARK 290      11555   -X+1/2,Y,-Z+1/2                                         
REMARK 290      12555   X+1/2,-Y,-Z+1/2                                         
REMARK 290      13555   X+1/2,Y+1/2,Z                                           
REMARK 290      14555   -X+1/2,-Y+1/2,Z                                         
REMARK 290      15555   -X+1/2,Y+1/2,-Z                                         
REMARK 290      16555   X+1/2,-Y+1/2,-Z                                         
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   5  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   5  0.000000  1.000000  0.000000       43.64500            
REMARK 290   SMTRY3   5  0.000000  0.000000  1.000000       62.67250            
REMARK 290   SMTRY1   6 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   6  0.000000 -1.000000  0.000000       43.64500            
REMARK 290   SMTRY3   6  0.000000  0.000000  1.000000       62.67250            
REMARK 290   SMTRY1   7 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   7  0.000000  1.000000  0.000000       43.64500            
REMARK 290   SMTRY3   7  0.000000  0.000000 -1.000000       62.67250            
REMARK 290   SMTRY1   8  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   8  0.000000 -1.000000  0.000000       43.64500            
REMARK 290   SMTRY3   8  0.000000  0.000000 -1.000000       62.67250            
REMARK 290   SMTRY1   9  1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2   9  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   9  0.000000  0.000000  1.000000       62.67250            
REMARK 290   SMTRY1  10 -1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  10  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3  10  0.000000  0.000000  1.000000       62.67250            
REMARK 290   SMTRY1  11 -1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  11  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3  11  0.000000  0.000000 -1.000000       62.67250            
REMARK 290   SMTRY1  12  1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  12  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3  12  0.000000  0.000000 -1.000000       62.67250            
REMARK 290   SMTRY1  13  1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  13  0.000000  1.000000  0.000000       43.64500            
REMARK 290   SMTRY3  13  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1  14 -1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  14  0.000000 -1.000000  0.000000       43.64500            
REMARK 290   SMTRY3  14  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1  15 -1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  15  0.000000  1.000000  0.000000       43.64500            
REMARK 290   SMTRY3  15  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1  16  1.000000  0.000000  0.000000       20.64150            
REMARK 290   SMTRY2  16  0.000000 -1.000000  0.000000       43.64500            
REMARK 290   SMTRY3  16  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1, 2                                                    
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: TETRAMERIC                        
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B                                  
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT1   2 -1.000000  0.000000  0.000000       20.64150            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   2  0.000000  0.000000 -1.000000       62.67250            
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 2                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: OCTAMERIC                         
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B                                  
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT1   2 -1.000000  0.000000  0.000000       41.28300            
REMARK 350   BIOMT2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   2  0.000000  0.000000 -1.000000        0.00000            
REMARK 350   BIOMT1   3  1.000000  0.000000  0.000000      -20.64150            
REMARK 350   BIOMT2   3  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   3  0.000000  0.000000  1.000000       62.67250            
REMARK 350   BIOMT1   4 -1.000000  0.000000  0.000000       20.64150            
REMARK 350   BIOMT2   4  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   4  0.000000  0.000000 -1.000000       62.67250            
REMARK 375                                                                      
REMARK 375 SPECIAL POSITION                                                     
REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS            
REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL          
REMARK 375 POSITIONS.                                                           
REMARK 375                                                                      
REMARK 375 ATOM RES CSSEQI                                                      
REMARK 375      HOH A  27  LIES ON A SPECIAL POSITION.                          
REMARK 375      HOH A  72  LIES ON A SPECIAL POSITION.                          
REMARK 375      HOH A 105  LIES ON A SPECIAL POSITION.                          
REMARK 375      HOH B  94  LIES ON A SPECIAL POSITION.                          
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     MET A   180                                                      
REMARK 465     ARG A   181                                                      
REMARK 465     GLY A   182                                                      
REMARK 465     SER A   183                                                      
REMARK 465     HIS A   184                                                      
REMARK 465     HIS A   185                                                      
REMARK 465     HIS A   186                                                      
REMARK 465     HIS A   187                                                      
REMARK 465     HIS A   188                                                      
REMARK 465     HIS A   189                                                      
REMARK 465     PRO A   262                                                      
REMARK 465     LYS A   263                                                      
REMARK 465     HIS A   264                                                      
REMARK 465     ASN A   265                                                      
REMARK 465     LYS A   266                                                      
REMARK 465     LEU A   267                                                      
REMARK 465     ASN A   268                                                      
REMARK 465      DG B     1                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500     DA B   5   O4' -  C1' -  N9  ANGL. DEV. =  -4.3 DEGREES          
REMARK 500     DG B   8   O4' -  C1' -  N9  ANGL. DEV. =   4.9 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE PO4 B 11                  
DBREF  3D2W A  192   265  UNP    Q921F2   TADBP_MOUSE    192    265             
DBREF  3D2W B    1    10  PDB    3D2W     3D2W             1     10             
SEQADV 3D2W MET A  180  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W ARG A  181  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W GLY A  182  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W SER A  183  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  184  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  185  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  186  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  187  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  188  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W HIS A  189  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W GLY A  190  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W SER A  191  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W LYS A  266  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W LEU A  267  UNP  Q921F2              EXPRESSION TAG                 
SEQADV 3D2W ASN A  268  UNP  Q921F2              EXPRESSION TAG                 
SEQRES   1 A   89  MET ARG GLY SER HIS HIS HIS HIS HIS HIS GLY SER LYS          
SEQRES   2 A   89  VAL PHE VAL GLY ARG CYS THR GLU ASP MET THR ALA GLU          
SEQRES   3 A   89  GLU LEU GLN GLN PHE PHE CYS GLN TYR GLY GLU VAL VAL          
SEQRES   4 A   89  ASP VAL PHE ILE PRO LYS PRO PHE ARG ALA PHE ALA PHE          
SEQRES   5 A   89  VAL THR PHE ALA ASP ASP LYS VAL ALA GLN SER LEU CYS          
SEQRES   6 A   89  GLY GLU ASP LEU ILE ILE LYS GLY ILE SER VAL HIS ILE          
SEQRES   7 A   89  SER ASN ALA GLU PRO LYS HIS ASN LYS LEU ASN                  
SEQRES   1 B   10   DG  DT  DT  DG  DA  DG  DC  DG  DT  DT                      
HET    PO4  B  11       5                                                       
HETNAM     PO4 PHOSPHATE ION                                                    
FORMUL   3  PO4    O4 P 3-                                                      
FORMUL   4  HOH   *116(H2 O)                                                    
HELIX    1   1 THR A  203  CYS A  212  1                                  10    
HELIX    2   2 ASP A  236  CYS A  244  1                                   9    
SHEET    1   A 5 VAL A 217  PHE A 221  0                                        
SHEET    2   A 5 PHE A 229  PHE A 234 -1  O  THR A 233   N  VAL A 218           
SHEET    3   A 5 LYS A 192  GLY A 196 -1  N  VAL A 195   O  ALA A 230           
SHEET    4   A 5 ILE A 253  ASN A 259 -1  O  SER A 258   N  PHE A 194           
SHEET    5   A 5 ASP A 247  ILE A 250 -1  N  LEU A 248   O  VAL A 255           
CISPEP   1 LYS A  224    PRO A  225          0         1.60                     
SITE     1 AC1  6 GLY A 245  HIS A 256  SER A 258   DT B   2                    
SITE     2 AC1  6 HOH B  93  HOH B  94                                          
CRYST1   41.283   87.290  125.345  90.00  90.00  90.00 F 2 2 2      16          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.024223  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.011456  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.007978        0.00000                         
ATOM      1  N   GLY A 190       7.402   7.163  12.588  1.00 29.19           N  
ATOM      2  CA  GLY A 190       8.241   8.196  13.252  1.00 27.95           C  
ATOM      3  C   GLY A 190       8.778   7.692  14.578  1.00 27.05           C  
ATOM      4  O   GLY A 190       8.209   7.964  15.641  1.00 28.12           O  
ATOM      5  N   SER A 191       9.879   6.949  14.529  1.00 25.51           N  
ATOM      6  CA  SER A 191      10.414   6.351  15.748  1.00 23.73           C  
ATOM      7  C   SER A 191      11.741   6.975  16.173  1.00 22.25           C  
ATOM      8  O   SER A 191      12.466   6.402  16.977  1.00 21.41           O  
ATOM      9  CB  SER A 191      10.543   4.836  15.613  1.00 24.05           C  
ATOM     10  OG  SER A 191      11.588   4.496  14.734  1.00 26.86           O  
ATOM     11  N   LYS A 192      12.036   8.151  15.634  1.00 20.59           N  
ATOM     12  CA  LYS A 192      13.250   8.882  16.000  1.00 19.36           C  
ATOM     13  C   LYS A 192      12.895  10.160  16.734  1.00 18.53           C  
ATOM     14  O   LYS A 192      11.984  10.889  16.328  1.00 17.66           O  
ATOM     15  CB  LYS A 192      14.079   9.208  14.759  1.00 19.96           C  
ATOM     16  CG  LYS A 192      15.503   9.688  15.082  1.00 21.27           C  
ATOM     17  CD  LYS A 192      16.237  10.197  13.866  1.00 26.30           C  
ATOM     18  CE  LYS A 192      16.909   9.088  13.093  1.00 28.08           C  
ATOM     19  NZ  LYS A 192      17.912   9.650  12.145  1.00 28.55           N  
ATOM     20  N   VAL A 193      13.598  10.421  17.833  1.00 16.39           N  
ATOM     21  CA  VAL A 193      13.405  11.682  18.555  1.00 15.66           C  
ATOM     22  C   VAL A 193      14.658  12.546  18.488  1.00 14.68           C  
ATOM     23  O   VAL A 193      15.779  12.032  18.386  1.00 14.45           O  
ATOM     24  CB  VAL A 193      13.011  11.467  20.052  1.00 15.73           C  
ATOM     25  CG1 VAL A 193      11.731  10.656  20.174  1.00 16.79           C  
ATOM     26  CG2 VAL A 193      14.139  10.809  20.852  1.00 17.43           C  
ATOM     27  N   PHE A 194      14.438  13.851  18.549  1.00 13.13           N  
ATOM     28  CA  PHE A 194      15.490  14.848  18.701  1.00 13.20           C  
ATOM     29  C   PHE A 194      15.661  15.119  20.192  1.00 12.90           C  
ATOM     30  O   PHE A 194      14.689  15.246  20.926  1.00 13.25           O  
ATOM     31  CB  PHE A 194      15.080  16.105  17.946  1.00 13.03           C  
ATOM     32  CG  PHE A 194      15.927  17.313  18.224  1.00 13.30           C  
ATOM     33  CD1 PHE A 194      17.015  17.609  17.412  1.00 13.65           C  
ATOM     34  CD2 PHE A 194      15.599  18.197  19.255  1.00 12.70           C  
ATOM     35  CE1 PHE A 194      17.779  18.749  17.624  1.00 13.18           C  
ATOM     36  CE2 PHE A 194      16.373  19.350  19.487  1.00 13.67           C  
ATOM     37  CZ  PHE A 194      17.462  19.624  18.659  1.00 14.46           C  
ATOM     38  N   VAL A 195      16.912  15.191  20.631  1.00 12.42           N  
ATOM     39  CA  VAL A 195      17.217  15.402  22.047  1.00 12.02           C  
ATOM     40  C   VAL A 195      17.999  16.697  22.176  1.00 12.25           C  
ATOM     41  O   VAL A 195      19.145  16.765  21.754  1.00 13.38           O  
ATOM     42  CB  VAL A 195      18.033  14.246  22.612  1.00 11.32           C  
ATOM     43  CG1 VAL A 195      18.253  14.461  24.133  1.00 11.91           C  
ATOM     44  CG2 VAL A 195      17.317  12.904  22.364  1.00 12.60           C  
ATOM     45  N   GLY A 196      17.369  17.737  22.713  1.00 12.18           N  
ATOM     46  CA  GLY A 196      17.993  19.053  22.745  1.00 11.42           C  
ATOM     47  C   GLY A 196      18.637  19.332  24.090  1.00 11.77           C  
ATOM     48  O   GLY A 196      18.227  18.765  25.077  1.00 12.06           O  
ATOM     49  N   ARG A 197      19.651  20.207  24.109  1.00 12.06           N  
ATOM     50  CA  ARG A 197      20.392  20.572  25.324  1.00 11.98           C  
ATOM     51  C   ARG A 197      21.298  19.466  25.850  1.00 12.18           C  
ATOM     52  O   ARG A 197      21.550  19.374  27.066  1.00 12.66           O  
ATOM     53  CB  ARG A 197      19.465  21.111  26.438  1.00 11.66           C  
ATOM     54  CG  ARG A 197      18.520  22.221  25.978  1.00 10.75           C  
ATOM     55  CD  ARG A 197      17.752  22.853  27.134  1.00 12.38           C  
ATOM     56  NE  ARG A 197      16.890  21.911  27.845  1.00 10.89           N  
ATOM     57  CZ  ARG A 197      15.554  21.907  27.829  1.00 12.31           C  
ATOM     58  NH1 ARG A 197      14.857  22.781  27.099  1.00 12.10           N  
ATOM     59  NH2 ARG A 197      14.907  21.009  28.568  1.00 13.41           N  
ATOM     60  N   CYS A 198      21.796  18.621  24.942  1.00 12.13           N  
ATOM     61  CA  CYS A 198      22.833  17.658  25.314  1.00 13.06           C  
ATOM     62  C   CYS A 198      24.097  18.411  25.707  1.00 12.69           C  
ATOM     63  O   CYS A 198      24.301  19.552  25.295  1.00 14.03           O  
ATOM     64  CB  CYS A 198      23.128  16.711  24.149  1.00 13.14           C  
ATOM     65  SG  CYS A 198      21.780  15.550  23.850  1.00 14.47           S  
ATOM     66  N   THR A 199      24.908  17.783  26.543  1.00 13.85           N  
ATOM     67  CA  THR A 199      26.208  18.346  26.891  1.00 14.79           C  
ATOM     68  C   THR A 199      27.281  17.500  26.223  1.00 15.76           C  
ATOM     69  O   THR A 199      27.022  16.368  25.823  1.00 16.35           O  
ATOM     70  CB  THR A 199      26.424  18.375  28.409  1.00 14.80           C  
ATOM     71  OG1 THR A 199      26.274  17.048  28.925  1.00 15.54           O  
ATOM     72  CG2 THR A 199      25.430  19.316  29.074  1.00 15.26           C  
ATOM     73  N   GLU A 200      28.493  18.039  26.134  1.00 16.82           N  
ATOM     74  CA  GLU A 200      29.552  17.368  25.380  1.00 18.91           C  
ATOM     75  C   GLU A 200      29.986  16.019  25.938  1.00 18.94           C  
ATOM     76  O   GLU A 200      30.415  15.137  25.177  1.00 19.54           O  
ATOM     77  CB  GLU A 200      30.761  18.280  25.187  1.00 19.32           C  
ATOM     78  CG  GLU A 200      31.856  17.630  24.319  1.00 23.55           C  
ATOM     79  CD  GLU A 200      32.638  18.617  23.503  1.00 27.26           C  
ATOM     80  OE1 GLU A 200      32.428  19.832  23.693  1.00 28.70           O  
ATOM     81  OE2 GLU A 200      33.453  18.172  22.651  1.00 29.87           O  
ATOM     82  N   ASP A 201      29.882  15.854  27.255  1.00 19.40           N  
ATOM     83  CA  ASP A 201      30.268  14.603  27.900  1.00 19.88           C  
ATOM     84  C   ASP A 201      29.272  13.467  27.687  1.00 19.53           C  
ATOM     85  O   ASP A 201      29.554  12.311  28.030  1.00 19.83           O  
ATOM     86  CB  ASP A 201      30.480  14.827  29.402  1.00 20.36           C  
ATOM     87  CG  ASP A 201      29.245  15.380  30.086  1.00 22.17           C  
ATOM     88  OD1 ASP A 201      28.626  14.659  30.900  1.00 25.13           O  
ATOM     89  OD2 ASP A 201      28.882  16.545  29.810  1.00 25.18           O  
ATOM     90  N   MET A 202      28.100  13.781  27.122  1.00 18.85           N  
ATOM     91  CA  MET A 202      27.100  12.757  26.842  1.00 18.63           C  
ATOM     92  C   MET A 202      27.465  11.927  25.624  1.00 19.01           C  
ATOM     93  O   MET A 202      27.332  12.383  24.493  1.00 20.83           O  
ATOM     94  CB  MET A 202      25.738  13.403  26.628  1.00 18.39           C  
ATOM     95  CG  MET A 202      25.198  14.020  27.879  1.00 18.18           C  
ATOM     96  SD  MET A 202      23.583  14.756  27.571  1.00 17.24           S  
ATOM     97  CE  MET A 202      23.108  15.234  29.220  1.00 19.20           C  
ATOM     98  N   THR A 203      27.916  10.702  25.858  1.00 18.64           N  
ATOM     99  CA  THR A 203      28.353   9.850  24.759  1.00 18.04           C  
ATOM    100  C   THR A 203      27.179   9.076  24.170  1.00 17.91           C  
ATOM    101  O   THR A 203      26.121   8.958  24.795  1.00 16.61           O  
ATOM    102  CB  THR A 203      29.372   8.829  25.249  1.00 17.94           C  
ATOM    103  OG1 THR A 203      28.742   7.961  26.188  1.00 16.82           O  
ATOM    104  CG2 THR A 203      30.584   9.530  25.919  1.00 18.89           C  
ATOM    105  N   ALA A 204      27.382   8.527  22.976  1.00 17.66           N  
ATOM    106  CA  ALA A 204      26.361   7.677  22.360  1.00 18.06           C  
ATOM    107  C   ALA A 204      25.988   6.487  23.243  1.00 18.03           C  
ATOM    108  O   ALA A 204      24.804   6.175  23.398  1.00 18.00           O  
ATOM    109  CB  ALA A 204      26.797   7.232  20.948  1.00 18.04           C  
ATOM    110  N   GLU A 205      26.986   5.853  23.870  1.00 17.79           N  
ATOM    111  CA  GLU A 205      26.740   4.764  24.796  1.00 18.59           C  
ATOM    112  C   GLU A 205      25.877   5.224  25.966  1.00 17.57           C  
ATOM    113  O   GLU A 205      24.933   4.547  26.347  1.00 17.14           O  
ATOM    114  CB  GLU A 205      28.059   4.192  25.331  1.00 18.21           C  
ATOM    115  CG  GLU A 205      27.859   2.916  26.115  1.00 20.81           C  
ATOM    116  CD  GLU A 205      29.143   2.359  26.717  1.00 21.39           C  
ATOM    117  OE1 GLU A 205      29.043   1.425  27.537  1.00 26.58           O  
ATOM    118  OE2 GLU A 205      30.234   2.860  26.380  1.00 26.82           O  
ATOM    119  N   GLU A 206      26.212   6.381  26.534  1.00 17.09           N  
ATOM    120  CA  GLU A 206      25.450   6.914  27.672  1.00 16.85           C  
ATOM    121  C   GLU A 206      23.995   7.195  27.300  1.00 15.87           C  
ATOM    122  O   GLU A 206      23.073   6.824  28.037  1.00 15.47           O  
ATOM    123  CB  GLU A 206      26.119   8.165  28.240  1.00 17.43           C  
ATOM    124  CG  GLU A 206      27.349   7.809  29.072  1.00 20.83           C  
ATOM    125  CD  GLU A 206      28.061   9.017  29.646  1.00 24.69           C  
ATOM    126  OE1 GLU A 206      27.778  10.146  29.204  1.00 25.90           O  
ATOM    127  OE2 GLU A 206      28.912   8.820  30.547  1.00 28.12           O  
ATOM    128  N   LEU A 207      23.795   7.809  26.143  1.00 15.56           N  
ATOM    129  CA  LEU A 207      22.436   8.132  25.695  1.00 15.16           C  
ATOM    130  C   LEU A 207      21.646   6.858  25.431  1.00 15.65           C  
ATOM    131  O   LEU A 207      20.479   6.754  25.786  1.00 14.59           O  
ATOM    132  CB  LEU A 207      22.452   9.025  24.453  1.00 15.51           C  
ATOM    133  CG  LEU A 207      22.892  10.488  24.630  1.00 15.28           C  
ATOM    134  CD1 LEU A 207      22.689  11.219  23.317  1.00 17.51           C  
ATOM    135  CD2 LEU A 207      22.126  11.172  25.758  1.00 18.29           C  
ATOM    136  N   GLN A 208      22.291   5.878  24.807  1.00 16.62           N  
ATOM    137  CA  GLN A 208      21.617   4.620  24.550  1.00 17.07           C  
ATOM    138  C   GLN A 208      21.222   3.925  25.862  1.00 16.51           C  
ATOM    139  O   GLN A 208      20.090   3.465  26.024  1.00 16.58           O  
ATOM    140  CB  GLN A 208      22.500   3.753  23.665  1.00 17.56           C  
ATOM    141  CG  GLN A 208      21.810   2.552  23.175  1.00 20.09           C  
ATOM    142  CD  GLN A 208      22.219   1.368  23.944  1.00 23.75           C  
ATOM    143  OE1 GLN A 208      21.506   0.916  24.845  1.00 25.05           O  
ATOM    144  NE2 GLN A 208      23.409   0.874  23.648  1.00 20.05           N  
ATOM    145  N   GLN A 209      22.156   3.873  26.819  1.00 15.90           N  
ATOM    146  CA  GLN A 209      21.881   3.331  28.141  1.00 16.07           C  
ATOM    147  C   GLN A 209      20.716   4.036  28.816  1.00 15.78           C  
ATOM    148  O   GLN A 209      19.865   3.398  29.433  1.00 17.23           O  
ATOM    149  CB  GLN A 209      23.133   3.424  29.020  1.00 16.81           C  
ATOM    150  CG  GLN A 209      24.183   2.384  28.638  1.00 16.82           C  
ATOM    151  CD  GLN A 209      25.575   2.737  29.118  1.00 19.94           C  
ATOM    152  OE1 GLN A 209      25.864   3.896  29.446  1.00 23.36           O  
ATOM    153  NE2 GLN A 209      26.464   1.739  29.135  1.00 19.27           N  
ATOM    154  N   PHE A 210      20.687   5.360  28.703  1.00 15.32           N  
ATOM    155  CA  PHE A 210      19.614   6.127  29.322  1.00 13.80           C  
ATOM    156  C   PHE A 210      18.286   5.851  28.636  1.00 13.20           C  
ATOM    157  O   PHE A 210      17.299   5.547  29.294  1.00 14.72           O  
ATOM    158  CB  PHE A 210      19.913   7.630  29.283  1.00 13.34           C  
ATOM    159  CG  PHE A 210      18.807   8.468  29.878  1.00 13.62           C  
ATOM    160  CD1 PHE A 210      17.826   9.037  29.059  1.00 13.73           C  
ATOM    161  CD2 PHE A 210      18.744   8.681  31.256  1.00 14.59           C  
ATOM    162  CE1 PHE A 210      16.803   9.795  29.603  1.00 13.86           C  
ATOM    163  CE2 PHE A 210      17.726   9.446  31.817  1.00 14.69           C  
ATOM    164  CZ  PHE A 210      16.740   9.988  30.994  1.00 12.61           C  
ATOM    165  N   PHE A 211      18.270   5.944  27.315  1.00 13.78           N  
ATOM    166  CA  PHE A 211      17.001   5.869  26.585  1.00 13.90           C  
ATOM    167  C   PHE A 211      16.418   4.467  26.443  1.00 15.30           C  
ATOM    168  O   PHE A 211      15.219   4.324  26.256  1.00 14.93           O  
ATOM    169  CB  PHE A 211      17.118   6.555  25.229  1.00 12.98           C  
ATOM    170  CG  PHE A 211      17.017   8.053  25.334  1.00 11.98           C  
ATOM    171  CD1 PHE A 211      18.157   8.840  25.328  1.00 11.67           C  
ATOM    172  CD2 PHE A 211      15.772   8.660  25.528  1.00 11.91           C  
ATOM    173  CE1 PHE A 211      18.073  10.223  25.462  1.00 11.29           C  
ATOM    174  CE2 PHE A 211      15.666  10.040  25.645  1.00 10.67           C  
ATOM    175  CZ  PHE A 211      16.828  10.830  25.612  1.00 11.67           C  
ATOM    176  N   CYS A 212      17.243   3.437  26.576  1.00 16.53           N  
ATOM    177  CA  CYS A 212      16.698   2.084  26.448  1.00 17.51           C  
ATOM    178  C   CYS A 212      15.830   1.651  27.646  1.00 18.00           C  
ATOM    179  O   CYS A 212      15.183   0.591  27.601  1.00 18.06           O  
ATOM    180  CB  CYS A 212      17.792   1.079  26.131  1.00 18.06           C  
ATOM    181  SG  CYS A 212      18.773   0.596  27.549  1.00 20.56           S  
ATOM    182  N   GLN A 213      15.773   2.466  28.700  1.00 18.08           N  
ATOM    183  CA  GLN A 213      14.802   2.240  29.771  1.00 18.97           C  
ATOM    184  C   GLN A 213      13.356   2.286  29.269  1.00 18.60           C  
ATOM    185  O   GLN A 213      12.485   1.641  29.850  1.00 19.40           O  
ATOM    186  CB  GLN A 213      14.980   3.212  30.947  1.00 19.17           C  
ATOM    187  CG  GLN A 213      14.622   4.655  30.608  1.00 19.85           C  
ATOM    188  CD  GLN A 213      14.849   5.612  31.760  1.00 20.20           C  
ATOM    189  OE1 GLN A 213      15.757   6.454  31.724  1.00 21.61           O  
ATOM    190  NE2 GLN A 213      14.031   5.485  32.792  1.00 17.62           N  
ATOM    191  N   TYR A 214      13.123   3.036  28.190  1.00 18.62           N  
ATOM    192  CA  TYR A 214      11.781   3.244  27.618  1.00 18.29           C  
ATOM    193  C   TYR A 214      11.406   2.218  26.549  1.00 18.40           C  
ATOM    194  O   TYR A 214      10.227   2.006  26.247  1.00 19.08           O  
ATOM    195  CB  TYR A 214      11.666   4.657  27.043  1.00 17.65           C  
ATOM    196  CG  TYR A 214      12.099   5.748  28.007  1.00 16.43           C  
ATOM    197  CD1 TYR A 214      13.241   6.509  27.758  1.00 17.02           C  
ATOM    198  CD2 TYR A 214      11.377   6.002  29.170  1.00 17.30           C  
ATOM    199  CE1 TYR A 214      13.638   7.509  28.626  1.00 15.25           C  
ATOM    200  CE2 TYR A 214      11.774   7.009  30.066  1.00 17.52           C  
ATOM    201  CZ  TYR A 214      12.912   7.750  29.780  1.00 17.45           C  
ATOM    202  OH  TYR A 214      13.319   8.737  30.649  1.00 17.24           O  
ATOM    203  N   GLY A 215      12.415   1.593  25.967  1.00 18.25           N  
ATOM    204  CA  GLY A 215      12.208   0.643  24.897  1.00 17.86           C  
ATOM    205  C   GLY A 215      13.502   0.452  24.155  1.00 17.42           C  
ATOM    206  O   GLY A 215      14.459   1.207  24.334  1.00 17.37           O  
ATOM    207  N   GLU A 216      13.527  -0.557  23.302  1.00 17.10           N  
ATOM    208  CA  GLU A 216      14.700  -0.834  22.494  1.00 17.12           C  
ATOM    209  C   GLU A 216      15.158   0.372  21.669  1.00 17.46           C  
ATOM    210  O   GLU A 216      14.372   0.982  20.935  1.00 15.73           O  
ATOM    211  CB  GLU A 216      14.434  -2.043  21.594  1.00 17.07           C  
ATOM    212  CG  GLU A 216      15.687  -2.562  20.954  1.00 18.08           C  
ATOM    213  CD  GLU A 216      15.431  -3.612  19.904  1.00 20.94           C  
ATOM    214  OE1 GLU A 216      14.278  -4.064  19.776  1.00 21.68           O  
ATOM    215  OE2 GLU A 216      16.400  -3.967  19.210  1.00 20.70           O  
ATOM    216  N   VAL A 217      16.432   0.735  21.832  1.00 17.15           N  
ATOM    217  CA  VAL A 217      17.075   1.770  21.029  1.00 18.26           C  
ATOM    218  C   VAL A 217      17.923   1.113  19.948  1.00 19.33           C  
ATOM    219  O   VAL A 217      18.707   0.207  20.236  1.00 20.59           O  
ATOM    220  CB  VAL A 217      17.976   2.695  21.912  1.00 17.75           C  
ATOM    221  CG1 VAL A 217      18.771   3.686  21.052  1.00 17.71           C  
ATOM    222  CG2 VAL A 217      17.133   3.418  22.961  1.00 19.02           C  
ATOM    223  N   VAL A 218      17.758   1.570  18.716  1.00 20.54           N  
ATOM    224  CA  VAL A 218      18.457   0.965  17.576  1.00 21.92           C  
ATOM    225  C   VAL A 218      19.521   1.866  16.953  1.00 22.09           C  
ATOM    226  O   VAL A 218      20.414   1.386  16.275  1.00 23.13           O  
ATOM    227  CB  VAL A 218      17.481   0.389  16.512  1.00 22.05           C  
ATOM    228  CG1 VAL A 218      16.708  -0.792  17.106  1.00 23.64           C  
ATOM    229  CG2 VAL A 218      16.534   1.450  15.966  1.00 22.01           C  
ATOM    230  N   ASP A 219      19.446   3.172  17.200  1.00 21.32           N  
ATOM    231  CA  ASP A 219      20.526   4.058  16.781  1.00 20.84           C  
ATOM    232  C   ASP A 219      20.620   5.311  17.645  1.00 19.88           C  
ATOM    233  O   ASP A 219      19.647   5.718  18.264  1.00 18.85           O  
ATOM    234  CB  ASP A 219      20.360   4.458  15.318  1.00 21.84           C  
ATOM    235  CG  ASP A 219      21.692   4.664  14.610  1.00 25.25           C  
ATOM    236  OD1 ASP A 219      22.765   4.659  15.269  1.00 28.21           O  
ATOM    237  OD2 ASP A 219      21.656   4.834  13.375  1.00 30.56           O  
ATOM    238  N   VAL A 220      21.814   5.898  17.682  1.00 18.88           N  
ATOM    239  CA  VAL A 220      22.035   7.193  18.326  1.00 17.70           C  
ATOM    240  C   VAL A 220      22.948   7.974  17.393  1.00 17.60           C  
ATOM    241  O   VAL A 220      23.936   7.433  16.902  1.00 18.99           O  
ATOM    242  CB  VAL A 220      22.719   7.081  19.716  1.00 17.83           C  
ATOM    243  CG1 VAL A 220      23.017   8.479  20.296  1.00 17.57           C  
ATOM    244  CG2 VAL A 220      21.871   6.286  20.694  1.00 17.36           C  
ATOM    245  N   PHE A 221      22.615   9.232  17.154  1.00 16.48           N  
ATOM    246  CA  PHE A 221      23.446  10.102  16.350  1.00 16.59           C  
ATOM    247  C   PHE A 221      23.796  11.338  17.158  1.00 16.42           C  
ATOM    248  O   PHE A 221      22.904  12.048  17.641  1.00 16.16           O  
ATOM    249  CB  PHE A 221      22.725  10.500  15.062  1.00 16.85           C  
ATOM    250  CG  PHE A 221      23.590  11.249  14.096  1.00 17.64           C  
ATOM    251  CD1 PHE A 221      23.780  12.619  14.230  1.00 18.86           C  
ATOM    252  CD2 PHE A 221      24.204  10.582  13.029  1.00 19.99           C  
ATOM    253  CE1 PHE A 221      24.586  13.323  13.334  1.00 20.91           C  
ATOM    254  CE2 PHE A 221      25.004  11.280  12.129  1.00 20.04           C  
ATOM    255  CZ  PHE A 221      25.197  12.646  12.284  1.00 18.90           C  
ATOM    256  N   ILE A 222      25.097  11.588  17.288  1.00 16.68           N  
ATOM    257  CA  ILE A 222      25.611  12.779  17.938  1.00 17.39           C  
ATOM    258  C   ILE A 222      26.449  13.541  16.913  1.00 18.02           C  
ATOM    259  O   ILE A 222      27.452  13.014  16.425  1.00 17.69           O  
ATOM    260  CB  ILE A 222      26.465  12.426  19.190  1.00 17.37           C  
ATOM    261  CG1 ILE A 222      25.592  11.760  20.254  1.00 18.06           C  
ATOM    262  CG2 ILE A 222      27.177  13.683  19.743  1.00 17.10           C  
ATOM    263  CD1 ILE A 222      26.353  11.190  21.462  1.00 18.54           C  
ATOM    264  N   PRO A 223      26.039  14.775  16.577  1.00 18.68           N  
ATOM    265  CA  PRO A 223      26.817  15.559  15.619  1.00 19.27           C  
ATOM    266  C   PRO A 223      28.249  15.815  16.082  1.00 20.13           C  
ATOM    267  O   PRO A 223      28.516  15.941  17.282  1.00 19.50           O  
ATOM    268  CB  PRO A 223      26.049  16.879  15.547  1.00 19.34           C  
ATOM    269  CG  PRO A 223      24.646  16.488  15.904  1.00 19.42           C  
ATOM    270  CD  PRO A 223      24.850  15.519  17.024  1.00 18.69           C  
ATOM    271  N   LYS A 224      29.149  15.866  15.104  1.00 20.94           N  
ATOM    272  CA  LYS A 224      30.546  16.233  15.302  1.00 22.90           C  
ATOM    273  C   LYS A 224      30.894  17.259  14.245  1.00 22.77           C  
ATOM    274  O   LYS A 224      30.689  17.001  13.051  1.00 24.69           O  
ATOM    275  CB  LYS A 224      31.465  15.023  15.142  1.00 23.15           C  
ATOM    276  CG  LYS A 224      31.557  14.150  16.368  1.00 26.19           C  
ATOM    277  CD  LYS A 224      30.510  13.072  16.316  1.00 29.61           C  
ATOM    278  CE  LYS A 224      30.254  12.473  17.683  1.00 30.53           C  
ATOM    279  NZ  LYS A 224      29.457  11.246  17.529  1.00 29.82           N  
ATOM    280  N   PRO A 225      31.396  18.440  14.658  1.00 22.06           N  
ATOM    281  CA  PRO A 225      31.687  18.862  16.035  1.00 20.46           C  
ATOM    282  C   PRO A 225      30.440  19.069  16.896  1.00 18.98           C  
ATOM    283  O   PRO A 225      29.322  19.042  16.392  1.00 18.49           O  
ATOM    284  CB  PRO A 225      32.423  20.196  15.850  1.00 20.43           C  
ATOM    285  CG  PRO A 225      32.819  20.235  14.391  1.00 22.05           C  
ATOM    286  CD  PRO A 225      31.751  19.488  13.685  1.00 22.33           C  
ATOM    287  N   PHE A 226      30.660  19.271  18.190  1.00 17.76           N  
ATOM    288  CA  PHE A 226      29.579  19.354  19.178  1.00 17.19           C  
ATOM    289  C   PHE A 226      28.558  20.445  18.872  1.00 16.67           C  
ATOM    290  O   PHE A 226      28.908  21.610  18.690  1.00 16.76           O  
ATOM    291  CB  PHE A 226      30.190  19.576  20.562  1.00 16.44           C  
ATOM    292  CG  PHE A 226      29.172  19.771  21.659  1.00 16.64           C  
ATOM    293  CD1 PHE A 226      28.370  18.712  22.077  1.00 17.87           C  
ATOM    294  CD2 PHE A 226      29.025  21.009  22.268  1.00 17.27           C  
ATOM    295  CE1 PHE A 226      27.426  18.903  23.105  1.00 16.17           C  
ATOM    296  CE2 PHE A 226      28.100  21.198  23.301  1.00 15.73           C  
ATOM    297  CZ  PHE A 226      27.304  20.152  23.707  1.00 16.87           C  
ATOM    298  N   ARG A 227      27.282  20.055  18.850  1.00 16.19           N  
ATOM    299  CA  ARG A 227      26.196  20.981  18.584  1.00 16.04           C  
ATOM    300  C   ARG A 227      25.080  20.964  19.644  1.00 15.69           C  
ATOM    301  O   ARG A 227      24.044  21.623  19.467  1.00 15.76           O  
ATOM    302  CB  ARG A 227      25.612  20.726  17.187  1.00 17.11           C  
ATOM    303  CG  ARG A 227      26.504  21.183  16.051  1.00 19.62           C  
ATOM    304  CD  ARG A 227      25.653  21.826  14.956  1.00 26.65           C  
ATOM    305  NE  ARG A 227      25.162  20.822  14.029  1.00 31.37           N  
ATOM    306  CZ  ARG A 227      24.096  20.944  13.240  1.00 31.33           C  
ATOM    307  NH1 ARG A 227      23.342  22.039  13.240  1.00 31.80           N  
ATOM    308  NH2 ARG A 227      23.779  19.940  12.446  1.00 33.67           N  
ATOM    309  N   ALA A 228      25.298  20.231  20.738  1.00 15.23           N  
ATOM    310  CA  ALA A 228      24.375  20.224  21.907  1.00 14.50           C  
ATOM    311  C   ALA A 228      23.007  19.593  21.614  1.00 14.42           C  
ATOM    312  O   ALA A 228      21.986  19.970  22.194  1.00 14.12           O  
ATOM    313  CB  ALA A 228      24.221  21.619  22.509  1.00 14.58           C  
ATOM    314  N   PHE A 229      22.992  18.639  20.694  1.00 14.02           N  
ATOM    315  CA  PHE A 229      21.802  17.815  20.477  1.00 13.64           C  
ATOM    316  C   PHE A 229      22.175  16.426  19.978  1.00 13.18           C  
ATOM    317  O   PHE A 229      23.338  16.145  19.713  1.00 13.95           O  
ATOM    318  CB  PHE A 229      20.784  18.511  19.548  1.00 14.13           C  
ATOM    319  CG  PHE A 229      21.236  18.658  18.110  1.00 15.71           C  
ATOM    320  CD1 PHE A 229      21.853  19.827  17.684  1.00 18.57           C  
ATOM    321  CD2 PHE A 229      21.013  17.637  17.187  1.00 17.34           C  
ATOM    322  CE1 PHE A 229      22.244  19.975  16.359  1.00 19.17           C  
ATOM    323  CE2 PHE A 229      21.400  17.774  15.855  1.00 17.53           C  
ATOM    324  CZ  PHE A 229      22.034  18.941  15.446  1.00 16.89           C  
ATOM    325  N   ALA A 230      21.189  15.550  19.903  1.00 12.77           N  
ATOM    326  CA  ALA A 230      21.402  14.181  19.448  1.00 12.77           C  
ATOM    327  C   ALA A 230      20.101  13.661  18.851  1.00 12.88           C  
ATOM    328  O   ALA A 230      19.051  14.271  19.015  1.00 13.11           O  
ATOM    329  CB  ALA A 230      21.843  13.295  20.608  1.00 13.23           C  
ATOM    330  N   PHE A 231      20.193  12.550  18.136  1.00 13.30           N  
ATOM    331  CA  PHE A 231      18.997  11.824  17.714  1.00 13.19           C  
ATOM    332  C   PHE A 231      19.046  10.448  18.291  1.00 13.67           C  
ATOM    333  O   PHE A 231      20.107   9.811  18.325  1.00 14.26           O  
ATOM    334  CB  PHE A 231      18.925  11.737  16.188  1.00 14.41           C  
ATOM    335  CG  PHE A 231      18.689  13.055  15.527  1.00 15.44           C  
ATOM    336  CD1 PHE A 231      19.752  13.815  15.056  1.00 16.77           C  
ATOM    337  CD2 PHE A 231      17.402  13.560  15.421  1.00 16.14           C  
ATOM    338  CE1 PHE A 231      19.523  15.061  14.471  1.00 19.10           C  
ATOM    339  CE2 PHE A 231      17.168  14.793  14.837  1.00 18.04           C  
ATOM    340  CZ  PHE A 231      18.225  15.543  14.354  1.00 18.29           C  
ATOM    341  N   VAL A 232      17.894   9.972  18.748  1.00 13.05           N  
ATOM    342  CA  VAL A 232      17.811   8.618  19.287  1.00 13.43           C  
ATOM    343  C   VAL A 232      16.685   7.917  18.532  1.00 13.90           C  
ATOM    344  O   VAL A 232      15.565   8.440  18.455  1.00 12.97           O  
ATOM    345  CB  VAL A 232      17.514   8.593  20.815  1.00 13.31           C  
ATOM    346  CG1 VAL A 232      17.290   7.183  21.294  1.00 12.98           C  
ATOM    347  CG2 VAL A 232      18.647   9.252  21.629  1.00 13.88           C  
ATOM    348  N   THR A 233      16.998   6.741  17.991  1.00 14.85           N  
ATOM    349  CA  THR A 233      16.018   5.956  17.242  1.00 15.52           C  
ATOM    350  C   THR A 233      15.569   4.744  18.053  1.00 15.39           C  
ATOM    351  O   THR A 233      16.389   3.964  18.535  1.00 14.98           O  
ATOM    352  CB  THR A 233      16.577   5.497  15.867  1.00 16.32           C  
ATOM    353  OG1 THR A 233      17.135   6.621  15.184  1.00 17.21           O  
ATOM    354  CG2 THR A 233      15.444   4.931  15.004  1.00 17.09           C  
ATOM    355  N   PHE A 234      14.252   4.588  18.175  1.00 15.39           N  
ATOM    356  CA  PHE A 234      13.645   3.438  18.830  1.00 16.02           C  
ATOM    357  C   PHE A 234      13.121   2.430  17.827  1.00 16.84           C  
ATOM    358  O   PHE A 234      12.770   2.794  16.700  1.00 16.82           O  
ATOM    359  CB  PHE A 234      12.494   3.899  19.733  1.00 15.94           C  
ATOM    360  CG  PHE A 234      12.939   4.800  20.823  1.00 15.08           C  
ATOM    361  CD1 PHE A 234      12.987   6.177  20.636  1.00 15.00           C  
ATOM    362  CD2 PHE A 234      13.352   4.266  22.036  1.00 16.33           C  
ATOM    363  CE1 PHE A 234      13.438   7.003  21.665  1.00 15.25           C  
ATOM    364  CE2 PHE A 234      13.793   5.084  23.064  1.00 15.97           C  
ATOM    365  CZ  PHE A 234      13.852   6.457  22.863  1.00 15.01           C  
ATOM    366  N   ALA A 235      13.069   1.165  18.242  1.00 17.75           N  
ATOM    367  CA  ALA A 235      12.451   0.119  17.414  1.00 19.57           C  
ATOM    368  C   ALA A 235      10.939   0.346  17.312  1.00 20.46           C  
ATOM    369  O   ALA A 235      10.341   0.087  16.263  1.00 20.98           O  
ATOM    370  CB  ALA A 235      12.758  -1.259  17.973  1.00 19.41           C  
ATOM    371  N   ASP A 236      10.352   0.865  18.390  1.00 21.58           N  
ATOM    372  CA  ASP A 236       8.901   1.048  18.536  1.00 23.19           C  
ATOM    373  C   ASP A 236       8.480   2.535  18.428  1.00 23.74           C  
ATOM    374  O   ASP A 236       8.914   3.370  19.233  1.00 23.72           O  
ATOM    375  CB  ASP A 236       8.498   0.447  19.893  1.00 23.25           C  
ATOM    376  CG  ASP A 236       7.000   0.487  20.168  1.00 25.48           C  
ATOM    377  OD1 ASP A 236       6.211   0.907  19.297  1.00 28.71           O  
ATOM    378  OD2 ASP A 236       6.611   0.083  21.293  1.00 27.68           O  
ATOM    379  N   ASP A 237       7.620   2.859  17.452  1.00 25.01           N  
ATOM    380  CA  ASP A 237       7.094   4.233  17.283  1.00 25.70           C  
ATOM    381  C   ASP A 237       6.412   4.773  18.530  1.00 25.14           C  
ATOM    382  O   ASP A 237       6.573   5.944  18.870  1.00 24.86           O  
ATOM    383  CB  ASP A 237       6.080   4.312  16.133  1.00 26.67           C  
ATOM    384  CG  ASP A 237       6.732   4.312  14.771  1.00 29.53           C  
ATOM    385  OD1 ASP A 237       7.606   3.452  14.515  1.00 34.41           O  
ATOM    386  OD2 ASP A 237       6.351   5.168  13.944  1.00 33.76           O  
ATOM    387  N   LYS A 238       5.638   3.916  19.189  1.00 24.36           N  
ATOM    388  CA  LYS A 238       4.881   4.287  20.376  1.00 24.29           C  
ATOM    389  C   LYS A 238       5.796   4.845  21.463  1.00 23.37           C  
ATOM    390  O   LYS A 238       5.444   5.804  22.150  1.00 23.28           O  
ATOM    391  CB  LYS A 238       4.096   3.081  20.894  1.00 24.77           C  
ATOM    392  CG  LYS A 238       2.895   2.702  20.033  1.00 27.81           C  
ATOM    393  CD  LYS A 238       1.606   3.314  20.596  1.00 31.59           C  
ATOM    394  CE  LYS A 238       0.357   2.722  19.952  1.00 32.11           C  
ATOM    395  NZ  LYS A 238       0.228   3.080  18.503  1.00 35.17           N  
ATOM    396  N   VAL A 239       6.985   4.259  21.583  1.00 22.27           N  
ATOM    397  CA  VAL A 239       7.966   4.716  22.565  1.00 21.76           C  
ATOM    398  C   VAL A 239       8.466   6.130  22.242  1.00 21.42           C  
ATOM    399  O   VAL A 239       8.494   7.004  23.113  1.00 21.53           O  
ATOM    400  CB  VAL A 239       9.157   3.745  22.700  1.00 21.51           C  
ATOM    401  CG1 VAL A 239      10.170   4.294  23.728  1.00 21.39           C  
ATOM    402  CG2 VAL A 239       8.683   2.367  23.138  1.00 21.97           C  
ATOM    403  N   ALA A 240       8.833   6.366  20.990  1.00 21.09           N  
ATOM    404  CA  ALA A 240       9.321   7.687  20.579  1.00 20.67           C  
ATOM    405  C   ALA A 240       8.260   8.766  20.826  1.00 20.64           C  
ATOM    406  O   ALA A 240       8.542   9.833  21.382  1.00 20.51           O  
ATOM    407  CB  ALA A 240       9.743   7.660  19.116  1.00 20.97           C  
ATOM    408  N   GLN A 241       7.023   8.469  20.438  1.00 21.04           N  
ATOM    409  CA  GLN A 241       5.931   9.426  20.582  1.00 21.24           C  
ATOM    410  C   GLN A 241       5.601   9.764  22.038  1.00 20.31           C  
ATOM    411  O   GLN A 241       5.239  10.902  22.340  1.00 20.64           O  
ATOM    412  CB  GLN A 241       4.683   8.957  19.824  1.00 22.04           C  
ATOM    413  CG  GLN A 241       4.874   8.925  18.294  1.00 25.40           C  
ATOM    414  CD  GLN A 241       5.528  10.189  17.730  1.00 29.12           C  
ATOM    415  OE1 GLN A 241       6.599  10.128  17.124  1.00 31.36           O  
ATOM    416  NE2 GLN A 241       4.889  11.341  17.941  1.00 30.44           N  
ATOM    417  N   SER A 242       5.748   8.794  22.935  1.00 19.57           N  
ATOM    418  CA  SER A 242       5.447   9.002  24.351  1.00 18.84           C  
ATOM    419  C   SER A 242       6.440   9.964  25.011  1.00 17.26           C  
ATOM    420  O   SER A 242       6.123  10.614  26.002  1.00 17.66           O  
ATOM    421  CB  SER A 242       5.412   7.671  25.116  1.00 19.74           C  
ATOM    422  OG  SER A 242       6.684   7.038  25.085  1.00 23.16           O  
ATOM    423  N   LEU A 243       7.637  10.049  24.445  1.00 15.70           N  
ATOM    424  CA  LEU A 243       8.677  10.917  24.988  1.00 14.66           C  
ATOM    425  C   LEU A 243       8.611  12.345  24.475  1.00 14.23           C  
ATOM    426  O   LEU A 243       9.172  13.249  25.087  1.00 12.75           O  
ATOM    427  CB  LEU A 243      10.057  10.346  24.653  1.00 14.92           C  
ATOM    428  CG  LEU A 243      10.386   8.973  25.240  1.00 15.90           C  
ATOM    429  CD1 LEU A 243      11.734   8.531  24.689  1.00 18.12           C  
ATOM    430  CD2 LEU A 243      10.352   8.973  26.774  1.00 17.35           C  
ATOM    431  N   CYS A 244       7.962  12.552  23.334  1.00 13.65           N  
ATOM    432  CA  CYS A 244       7.979  13.871  22.702  1.00 14.65           C  
ATOM    433  C   CYS A 244       7.263  14.884  23.578  1.00 13.97           C  
ATOM    434  O   CYS A 244       6.171  14.614  24.094  1.00 15.00           O  
ATOM    435  CB  CYS A 244       7.367  13.808  21.307  1.00 15.38           C  
ATOM    436  SG  CYS A 244       8.431  12.984  20.115  1.00 19.06           S  
ATOM    437  N   GLY A 245       7.911  16.029  23.784  1.00 13.94           N  
ATOM    438  CA  GLY A 245       7.379  17.088  24.617  1.00 12.67           C  
ATOM    439  C   GLY A 245       7.838  17.027  26.065  1.00 12.24           C  
ATOM    440  O   GLY A 245       7.547  17.943  26.824  1.00 12.69           O  
ATOM    441  N   GLU A 246       8.551  15.962  26.430  1.00 10.47           N  
ATOM    442  CA  GLU A 246       9.054  15.786  27.802  1.00 10.36           C  
ATOM    443  C   GLU A 246      10.416  16.430  27.974  1.00 10.74           C  
ATOM    444  O   GLU A 246      11.143  16.643  27.006  1.00 11.31           O  
ATOM    445  CB  GLU A 246       9.147  14.304  28.154  1.00 11.41           C  
ATOM    446  CG  GLU A 246       7.766  13.660  28.099  1.00 11.60           C  
ATOM    447  CD  GLU A 246       7.701  12.263  28.666  1.00 13.35           C  
ATOM    448  OE1 GLU A 246       8.725  11.544  28.684  1.00 11.06           O  
ATOM    449  OE2 GLU A 246       6.587  11.877  29.088  1.00 13.79           O  
ATOM    450  N   ASP A 247      10.748  16.726  29.222  1.00 11.39           N  
ATOM    451  CA  ASP A 247      12.085  17.200  29.563  1.00 11.74           C  
ATOM    452  C   ASP A 247      12.615  16.202  30.570  1.00 12.00           C  
ATOM    453  O   ASP A 247      12.029  16.007  31.628  1.00 12.52           O  
ATOM    454  CB  ASP A 247      11.997  18.591  30.162  1.00 13.25           C  
ATOM    455  CG  ASP A 247      11.333  19.552  29.235  1.00 15.56           C  
ATOM    456  OD1 ASP A 247      11.983  19.875  28.221  1.00 16.61           O  
ATOM    457  OD2 ASP A 247      10.149  19.934  29.485  1.00 17.61           O  
ATOM    458  N   LEU A 248      13.700  15.530  30.195  1.00 11.73           N  
ATOM    459  CA  LEU A 248      14.192  14.391  30.954  1.00 12.10           C  
ATOM    460  C   LEU A 248      15.500  14.786  31.588  1.00 12.46           C  
ATOM    461  O   LEU A 248      16.168  15.687  31.101  1.00 13.16           O  
ATOM    462  CB  LEU A 248      14.390  13.200  30.021  1.00 11.98           C  
ATOM    463  CG  LEU A 248      13.104  12.729  29.330  1.00 11.53           C  
ATOM    464  CD1 LEU A 248      13.380  11.505  28.497  1.00 11.96           C  
ATOM    465  CD2 LEU A 248      12.005  12.424  30.341  1.00 12.13           C  
ATOM    466  N   ILE A 249      15.864  14.116  32.672  1.00 12.19           N  
ATOM    467  CA  ILE A 249      17.098  14.459  33.380  1.00 12.49           C  
ATOM    468  C   ILE A 249      18.143  13.376  33.113  1.00 12.56           C  
ATOM    469  O   ILE A 249      17.934  12.214  33.460  1.00 12.50           O  
ATOM    470  CB  ILE A 249      16.847  14.614  34.911  1.00 12.86           C  
ATOM    471  CG1 ILE A 249      15.922  15.809  35.215  1.00 13.29           C  
ATOM    472  CG2 ILE A 249      18.155  14.768  35.689  1.00 13.64           C  
ATOM    473  CD1 ILE A 249      16.505  17.178  34.916  1.00 16.11           C  
ATOM    474  N   ILE A 250      19.241  13.772  32.472  1.00 13.01           N  
ATOM    475  CA  ILE A 250      20.362  12.873  32.170  1.00 14.05           C  
ATOM    476  C   ILE A 250      21.585  13.443  32.880  1.00 15.54           C  
ATOM    477  O   ILE A 250      22.004  14.557  32.581  1.00 15.17           O  
ATOM    478  CB  ILE A 250      20.650  12.779  30.653  1.00 13.90           C  
ATOM    479  CG1 ILE A 250      19.419  12.258  29.906  1.00 13.54           C  
ATOM    480  CG2 ILE A 250      21.856  11.860  30.417  1.00 14.53           C  
ATOM    481  CD1 ILE A 250      19.566  12.152  28.407  1.00 15.30           C  
ATOM    482  N   LYS A 251      22.128  12.685  33.837  1.00 17.36           N  
ATOM    483  CA  LYS A 251      23.260  13.152  34.666  1.00 19.51           C  
ATOM    484  C   LYS A 251      23.016  14.580  35.218  1.00 18.98           C  
ATOM    485  O   LYS A 251      23.911  15.433  35.164  1.00 19.69           O  
ATOM    486  CB  LYS A 251      24.599  13.137  33.886  1.00 20.37           C  
ATOM    487  CG  LYS A 251      24.854  12.011  32.860  1.00 22.29           C  
ATOM    488  CD  LYS A 251      26.024  12.355  31.898  1.00 22.40           C  
ATOM    489  CE  LYS A 251      27.392  11.839  32.380  1.00 25.32           C  
ATOM    490  NZ  LYS A 251      28.485  12.036  31.363  1.00 24.45           N  
ATOM    491  N   GLY A 252      21.806  14.844  35.718  1.00 17.61           N  
ATOM    492  CA  GLY A 252      21.455  16.156  36.301  1.00 16.33           C  
ATOM    493  C   GLY A 252      21.094  17.287  35.344  1.00 14.83           C  
ATOM    494  O   GLY A 252      20.792  18.408  35.774  1.00 15.32           O  
ATOM    495  N   ILE A 253      21.107  16.992  34.046  1.00 13.40           N  
ATOM    496  CA  ILE A 253      20.871  17.990  32.995  1.00 13.21           C  
ATOM    497  C   ILE A 253      19.501  17.757  32.365  1.00 11.67           C  
ATOM    498  O   ILE A 253      19.138  16.629  32.077  1.00 10.99           O  
ATOM    499  CB  ILE A 253      21.932  17.877  31.914  1.00 14.06           C  
ATOM    500  CG1 ILE A 253      23.320  18.009  32.552  1.00 16.55           C  
ATOM    501  CG2 ILE A 253      21.703  18.930  30.818  1.00 13.33           C  
ATOM    502  CD1 ILE A 253      24.330  17.164  31.892  1.00 20.43           C  
ATOM    503  N   SER A 254      18.731  18.826  32.215  1.00 11.87           N  
ATOM    504  CA  SER A 254      17.414  18.726  31.589  1.00 11.81           C  
ATOM    505  C   SER A 254      17.552  18.845  30.093  1.00 11.80           C  
ATOM    506  O   SER A 254      17.968  19.888  29.595  1.00 11.91           O  
ATOM    507  CB  SER A 254      16.496  19.827  32.115  1.00 12.83           C  
ATOM    508  OG  SER A 254      15.256  19.803  31.435  1.00 13.10           O  
ATOM    509  N   VAL A 255      17.206  17.762  29.397  1.00 11.42           N  
ATOM    510  CA  VAL A 255      17.187  17.737  27.927  1.00 12.03           C  
ATOM    511  C   VAL A 255      15.739  17.737  27.440  1.00 11.88           C  
ATOM    512  O   VAL A 255      14.851  17.201  28.104  1.00 12.83           O  
ATOM    513  CB  VAL A 255      17.960  16.504  27.354  1.00 11.45           C  
ATOM    514  CG1 VAL A 255      19.438  16.525  27.820  1.00 12.58           C  
ATOM    515  CG2 VAL A 255      17.273  15.170  27.711  1.00 12.78           C  
ATOM    516  N   HIS A 256      15.495  18.324  26.278  1.00 12.17           N  
ATOM    517  CA  HIS A 256      14.135  18.399  25.775  1.00 12.92           C  
ATOM    518  C   HIS A 256      13.981  17.410  24.640  1.00 13.01           C  
ATOM    519  O   HIS A 256      14.837  17.336  23.757  1.00 13.64           O  
ATOM    520  CB  HIS A 256      13.779  19.812  25.280  1.00 13.77           C  
ATOM    521  CG  HIS A 256      12.339  19.936  24.886  1.00 14.68           C  
ATOM    522  ND1 HIS A 256      11.929  20.079  23.577  1.00 19.86           N  
ATOM    523  CD2 HIS A 256      11.211  19.878  25.630  1.00 15.55           C  
ATOM    524  CE1 HIS A 256      10.610  20.133  23.539  1.00 17.15           C  
ATOM    525  NE2 HIS A 256      10.146  20.007  24.766  1.00 18.78           N  
ATOM    526  N   ILE A 257      12.878  16.665  24.644  1.00 13.12           N  
ATOM    527  CA  ILE A 257      12.628  15.667  23.610  1.00 13.33           C  
ATOM    528  C   ILE A 257      11.611  16.189  22.596  1.00 14.19           C  
ATOM    529  O   ILE A 257      10.537  16.664  22.974  1.00 14.77           O  
ATOM    530  CB  ILE A 257      12.077  14.342  24.202  1.00 13.18           C  
ATOM    531  CG1 ILE A 257      12.873  13.892  25.443  1.00 12.52           C  
ATOM    532  CG2 ILE A 257      12.032  13.248  23.121  1.00 14.96           C  
ATOM    533  CD1 ILE A 257      14.387  13.718  25.202  1.00 15.53           C  
ATOM    534  N   SER A 258      11.940  16.079  21.314  1.00 15.04           N  
ATOM    535  CA  SER A 258      11.035  16.534  20.254  1.00 16.89           C  
ATOM    536  C   SER A 258      11.052  15.548  19.092  1.00 17.37           C  
ATOM    537  O   SER A 258      11.924  14.686  19.006  1.00 16.80           O  
ATOM    538  CB  SER A 258      11.465  17.923  19.778  1.00 17.26           C  
ATOM    539  OG  SER A 258      10.411  18.549  19.063  1.00 21.44           O  
ATOM    540  N   ASN A 259      10.079  15.651  18.194  1.00 18.81           N  
ATOM    541  CA  ASN A 259      10.119  14.809  17.014  1.00 20.86           C  
ATOM    542  C   ASN A 259      11.313  15.145  16.143  1.00 21.51           C  
ATOM    543  O   ASN A 259      11.679  16.315  16.014  1.00 21.44           O  
ATOM    544  CB  ASN A 259       8.838  14.971  16.206  1.00 21.54           C  
ATOM    545  CG  ASN A 259       7.692  14.225  16.816  1.00 24.00           C  
ATOM    546  OD1 ASN A 259       6.875  14.806  17.526  1.00 30.43           O  
ATOM    547  ND2 ASN A 259       7.633  12.916  16.567  1.00 28.48           N  
ATOM    548  N   ALA A 260      11.926  14.110  15.574  1.00 23.17           N  
ATOM    549  CA  ALA A 260      12.976  14.282  14.587  1.00 25.53           C  
ATOM    550  C   ALA A 260      12.326  14.577  13.240  1.00 27.17           C  
ATOM    551  O   ALA A 260      11.384  13.888  12.837  1.00 27.57           O  
ATOM    552  CB  ALA A 260      13.829  13.035  14.493  1.00 25.41           C  
ATOM    553  N   GLU A 261      12.809  15.613  12.568  1.00 29.04           N  
ATOM    554  CA  GLU A 261      12.295  15.962  11.241  1.00 30.85           C  
ATOM    555  C   GLU A 261      13.372  15.817  10.169  1.00 31.45           C  
ATOM    556  O   GLU A 261      14.557  15.683  10.488  1.00 32.39           O  
ATOM    557  CB  GLU A 261      11.667  17.364  11.233  1.00 31.57           C  
ATOM    558  CG  GLU A 261      12.407  18.440  12.025  1.00 34.26           C  
ATOM    559  CD  GLU A 261      13.477  19.156  11.218  1.00 36.75           C  
ATOM    560  OE1 GLU A 261      14.456  18.506  10.802  1.00 38.55           O  
ATOM    561  OE2 GLU A 261      13.350  20.386  11.016  1.00 39.45           O  
TER     562      GLU A 261                                                      
ATOM    563  P    DT B   2      20.683  26.331  18.481  0.50 35.42           P  
ATOM    564  OP1  DT B   2      21.805  27.097  19.073  0.50 34.87           O  
ATOM    565  OP2  DT B   2      20.160  26.704  17.145  0.50 34.95           O  
ATOM    566  O5'  DT B   2      21.062  24.776  18.434  0.50 32.54           O  
ATOM    567  C5'  DT B   2      20.825  23.943  19.573  0.50 32.28           C  
ATOM    568  C4'  DT B   2      19.670  22.987  19.317  0.50 30.94           C  
ATOM    569  O4'  DT B   2      19.073  22.606  20.582  0.50 30.39           O  
ATOM    570  C3'  DT B   2      18.548  23.568  18.456  0.50 31.16           C  
ATOM    571  O3'  DT B   2      18.297  22.741  17.327  0.50 33.00           O  
ATOM    572  C2'  DT B   2      17.331  23.654  19.365  0.50 30.04           C  
ATOM    573  C1'  DT B   2      17.670  22.689  20.493  0.50 28.94           C  
ATOM    574  N1   DT B   2      17.121  23.167  21.782  0.50 28.14           N  
ATOM    575  C2   DT B   2      15.975  22.581  22.281  0.50 28.19           C  
ATOM    576  O2   DT B   2      15.383  21.669  21.724  0.50 28.49           O  
ATOM    577  N3   DT B   2      15.535  23.110  23.469  0.50 26.62           N  
ATOM    578  C4   DT B   2      16.120  24.133  24.184  0.50 26.60           C  
ATOM    579  O4   DT B   2      15.641  24.519  25.238  0.50 27.77           O  
ATOM    580  C5   DT B   2      17.319  24.707  23.607  0.50 26.91           C  
ATOM    581  C7   DT B   2      18.069  25.811  24.295  0.50 25.71           C  
ATOM    582  C6   DT B   2      17.753  24.205  22.446  0.50 27.28           C  
ATOM    583  P    DT B   3      18.296  23.420  15.877  1.00 35.72           P  
ATOM    584  OP1  DT B   3      19.607  24.106  15.742  1.00 34.35           O  
ATOM    585  OP2  DT B   3      17.051  24.201  15.704  1.00 35.38           O  
ATOM    586  O5'  DT B   3      18.247  22.175  14.852  1.00 32.30           O  
ATOM    587  C5'  DT B   3      19.354  21.300  14.670  1.00 28.27           C  
ATOM    588  C4'  DT B   3      19.042  20.109  13.767  1.00 24.88           C  
ATOM    589  O4'  DT B   3      18.074  19.232  14.398  1.00 21.24           O  
ATOM    590  C3'  DT B   3      18.458  20.450  12.398  1.00 25.54           C  
ATOM    591  O3'  DT B   3      18.996  19.605  11.409  1.00 27.98           O  
ATOM    592  C2'  DT B   3      16.960  20.187  12.551  1.00 23.06           C  
ATOM    593  C1'  DT B   3      16.914  19.087  13.610  1.00 22.22           C  
ATOM    594  N1   DT B   3      15.772  19.197  14.562  1.00 21.40           N  
ATOM    595  C2   DT B   3      14.886  18.150  14.694  1.00 20.53           C  
ATOM    596  O2   DT B   3      14.970  17.110  14.066  1.00 20.40           O  
ATOM    597  N3   DT B   3      13.884  18.364  15.611  1.00 20.72           N  
ATOM    598  C4   DT B   3      13.690  19.490  16.392  1.00 22.61           C  
ATOM    599  O4   DT B   3      12.758  19.577  17.193  1.00 22.87           O  
ATOM    600  C5   DT B   3      14.660  20.541  16.217  1.00 22.53           C  
ATOM    601  C7   DT B   3      14.567  21.813  17.015  1.00 24.99           C  
ATOM    602  C6   DT B   3      15.641  20.348  15.322  1.00 22.33           C  
ATOM    603  P    DG B   4      20.481  19.844  10.840  1.00 30.33           P  
ATOM    604  OP1  DG B   4      20.897  21.263  11.003  1.00 31.22           O  
ATOM    605  OP2  DG B   4      20.455  19.186   9.519  1.00 31.46           O  
ATOM    606  O5'  DG B   4      21.403  18.997  11.829  1.00 29.59           O  
ATOM    607  C5'  DG B   4      21.163  17.635  12.037  1.00 27.87           C  
ATOM    608  C4'  DG B   4      22.444  16.828  11.944  1.00 26.03           C  
ATOM    609  O4'  DG B   4      22.171  15.484  12.404  1.00 24.22           O  
ATOM    610  C3'  DG B   4      23.008  16.594  10.549  1.00 25.92           C  
ATOM    611  O3'  DG B   4      24.282  16.016  10.713  1.00 27.27           O  
ATOM    612  C2'  DG B   4      22.053  15.528  10.045  1.00 25.09           C  
ATOM    613  C1'  DG B   4      22.006  14.628  11.284  1.00 23.68           C  
ATOM    614  N9   DG B   4      20.771  13.867  11.456  1.00 23.48           N  
ATOM    615  C8   DG B   4      20.711  12.544  11.824  1.00 23.05           C  
ATOM    616  N7   DG B   4      19.493  12.086  11.909  1.00 23.39           N  
ATOM    617  C5   DG B   4      18.694  13.174  11.582  1.00 22.60           C  
ATOM    618  C6   DG B   4      17.281  13.282  11.516  1.00 22.84           C  
ATOM    619  O6   DG B   4      16.442  12.401  11.729  1.00 23.76           O  
ATOM    620  N1   DG B   4      16.842  14.551  11.148  1.00 23.72           N  
ATOM    621  C2   DG B   4      17.678  15.606  10.878  1.00 23.34           C  
ATOM    622  N2   DG B   4      17.072  16.755  10.548  1.00 23.47           N  
ATOM    623  N3   DG B   4      19.008  15.526  10.949  1.00 23.75           N  
ATOM    624  C4   DG B   4      19.458  14.289  11.295  1.00 22.53           C  
ATOM    625  P    DA B   5      25.440  16.125   9.609  1.00 29.82           P  
ATOM    626  OP1  DA B   5      26.586  16.778  10.292  1.00 31.21           O  
ATOM    627  OP2  DA B   5      24.882  16.727   8.380  1.00 30.70           O  
ATOM    628  O5'  DA B   5      25.866  14.615   9.360  1.00 28.82           O  
ATOM    629  C5'  DA B   5      24.980  13.681   8.753  1.00 28.34           C  
ATOM    630  C4'  DA B   5      25.824  12.626   8.063  1.00 27.76           C  
ATOM    631  O4'  DA B   5      25.008  11.544   7.548  1.00 27.49           O  
ATOM    632  C3'  DA B   5      26.633  13.125   6.876  1.00 28.90           C  
ATOM    633  O3'  DA B   5      27.846  12.386   6.902  1.00 30.70           O  
ATOM    634  C2'  DA B   5      25.709  12.806   5.700  1.00 28.16           C  
ATOM    635  C1'  DA B   5      25.087  11.486   6.133  1.00 27.09           C  
ATOM    636  N9   DA B   5      23.710  11.232   5.721  1.00 25.82           N  
ATOM    637  C8   DA B   5      22.702  12.145   5.582  1.00 25.83           C  
ATOM    638  N7   DA B   5      21.556  11.606   5.235  1.00 26.24           N  
ATOM    639  C5   DA B   5      21.826  10.255   5.154  1.00 25.87           C  
ATOM    640  C6   DA B   5      21.021   9.136   4.831  1.00 26.68           C  
ATOM    641  N6   DA B   5      19.728   9.254   4.516  1.00 26.96           N  
ATOM    642  N1   DA B   5      21.603   7.909   4.832  1.00 26.59           N  
ATOM    643  C2   DA B   5      22.904   7.813   5.156  1.00 26.45           C  
ATOM    644  N3   DA B   5      23.759   8.795   5.485  1.00 26.64           N  
ATOM    645  C4   DA B   5      23.153   9.999   5.462  1.00 26.19           C  
ATOM    646  P    DG B   6      29.021  12.590   5.832  1.00 31.71           P  
ATOM    647  OP1  DG B   6      30.272  12.119   6.476  1.00 32.27           O  
ATOM    648  OP2  DG B   6      28.917  13.953   5.271  1.00 32.09           O  
ATOM    649  O5'  DG B   6      28.635  11.490   4.737  1.00 32.66           O  
ATOM    650  C5'  DG B   6      28.691  10.105   5.091  1.00 32.70           C  
ATOM    651  C4'  DG B   6      28.083   9.238   4.009  1.00 34.27           C  
ATOM    652  O4'  DG B   6      26.693   9.602   3.828  1.00 33.98           O  
ATOM    653  C3'  DG B   6      28.759   9.365   2.646  1.00 34.75           C  
ATOM    654  O3'  DG B   6      29.246   8.074   2.249  1.00 37.00           O  
ATOM    655  C2'  DG B   6      27.669   9.927   1.725  1.00 34.21           C  
ATOM    656  C1'  DG B   6      26.370   9.582   2.453  1.00 31.89           C  
ATOM    657  N9   DG B   6      25.264  10.528   2.293  1.00 31.26           N  
ATOM    658  C8   DG B   6      25.347  11.897   2.362  1.00 30.29           C  
ATOM    659  N7   DG B   6      24.207  12.499   2.203  1.00 30.72           N  
ATOM    660  C5   DG B   6      23.293  11.466   2.026  1.00 30.08           C  
ATOM    661  C6   DG B   6      21.890  11.513   1.811  1.00 30.13           C  
ATOM    662  O6   DG B   6      21.154  12.505   1.732  1.00 30.33           O  
ATOM    663  N1   DG B   6      21.341  10.238   1.676  1.00 30.76           N  
ATOM    664  C2   DG B   6      22.048   9.062   1.748  1.00 30.80           C  
ATOM    665  N2   DG B   6      21.323   7.939   1.604  1.00 30.76           N  
ATOM    666  N3   DG B   6      23.367   9.002   1.955  1.00 30.36           N  
ATOM    667  C4   DG B   6      23.925  10.238   2.085  1.00 30.26           C  
ATOM    668  P    DC B   7      30.010   7.821   0.855  1.00 38.08           P  
ATOM    669  OP1  DC B   7      30.924   6.675   1.077  1.00 38.70           O  
ATOM    670  OP2  DC B   7      30.527   9.099   0.312  1.00 36.56           O  
ATOM    671  O5'  DC B   7      28.810   7.316  -0.067  1.00 35.80           O  
ATOM    672  C5'  DC B   7      28.064   6.179   0.344  1.00 34.47           C  
ATOM    673  C4'  DC B   7      26.864   6.008  -0.559  1.00 33.36           C  
ATOM    674  O4'  DC B   7      25.951   7.108  -0.334  1.00 31.90           O  
ATOM    675  C3'  DC B   7      27.188   6.016  -2.055  1.00 33.37           C  
ATOM    676  O3'  DC B   7      26.506   4.930  -2.644  1.00 34.18           O  
ATOM    677  C2'  DC B   7      26.659   7.367  -2.539  1.00 31.39           C  
ATOM    678  C1'  DC B   7      25.466   7.507  -1.598  1.00 30.10           C  
ATOM    679  N1   DC B   7      24.863   8.868  -1.500  1.00 28.48           N  
ATOM    680  C2   DC B   7      23.465   8.983  -1.584  1.00 27.77           C  
ATOM    681  O2   DC B   7      22.779   7.958  -1.734  1.00 28.80           O  
ATOM    682  N3   DC B   7      22.914  10.222  -1.501  1.00 27.88           N  
ATOM    683  C4   DC B   7      23.696  11.297  -1.336  1.00 27.89           C  
ATOM    684  N4   DC B   7      23.120  12.499  -1.250  1.00 28.58           N  
ATOM    685  C5   DC B   7      25.118  11.196  -1.241  1.00 28.05           C  
ATOM    686  C6   DC B   7      25.652   9.974  -1.331  1.00 27.54           C  
ATOM    687  P    DG B   8      26.830   4.464  -4.144  1.00 35.13           P  
ATOM    688  OP1  DG B   8      26.333   3.077  -4.261  1.00 35.57           O  
ATOM    689  OP2  DG B   8      28.235   4.806  -4.471  1.00 35.27           O  
ATOM    690  O5'  DG B   8      25.875   5.421  -5.003  1.00 33.72           O  
ATOM    691  C5'  DG B   8      24.463   5.382  -4.835  1.00 32.73           C  
ATOM    692  C4'  DG B   8      23.830   6.541  -5.580  1.00 31.43           C  
ATOM    693  O4'  DG B   8      24.144   7.780  -4.893  1.00 29.91           O  
ATOM    694  C3'  DG B   8      24.325   6.730  -7.015  1.00 31.62           C  
ATOM    695  O3'  DG B   8      23.238   7.143  -7.816  1.00 33.61           O  
ATOM    696  C2'  DG B   8      25.322   7.869  -6.883  1.00 31.31           C  
ATOM    697  C1'  DG B   8      24.555   8.709  -5.864  1.00 28.24           C  
ATOM    698  N9   DG B   8      25.314   9.822  -5.308  1.00 27.32           N  
ATOM    699  C8   DG B   8      26.672   9.900  -5.084  1.00 27.30           C  
ATOM    700  N7   DG B   8      27.054  11.052  -4.603  1.00 26.87           N  
ATOM    701  C5   DG B   8      25.875  11.790  -4.508  1.00 27.02           C  
ATOM    702  C6   DG B   8      25.645  13.113  -4.051  1.00 27.61           C  
ATOM    703  O6   DG B   8      26.467  13.933  -3.621  1.00 27.99           O  
ATOM    704  N1   DG B   8      24.291  13.470  -4.118  1.00 27.74           N  
ATOM    705  C2   DG B   8      23.290  12.637  -4.576  1.00 27.21           C  
ATOM    706  N2   DG B   8      22.040  13.129  -4.580  1.00 27.62           N  
ATOM    707  N3   DG B   8      23.490  11.400  -5.006  1.00 26.57           N  
ATOM    708  C4   DG B   8      24.800  11.042  -4.944  1.00 26.91           C  
ATOM    709  P    DT B   9      23.122   6.741  -9.362  1.00 33.98           P  
ATOM    710  OP1  DT B   9      23.208   5.271  -9.479  1.00 33.68           O  
ATOM    711  OP2  DT B   9      24.040   7.627 -10.114  1.00 33.18           O  
ATOM    712  O5'  DT B   9      21.608   7.172  -9.663  1.00 31.18           O  
ATOM    713  C5'  DT B   9      20.566   6.712  -8.784  1.00 29.10           C  
ATOM    714  C4'  DT B   9      19.452   7.742  -8.690  1.00 27.07           C  
ATOM    715  O4'  DT B   9      19.930   8.939  -8.028  1.00 26.33           O  
ATOM    716  C3'  DT B   9      18.912   8.200 -10.045  1.00 27.13           C  
ATOM    717  O3'  DT B   9      17.520   8.420  -9.982  1.00 27.86           O  
ATOM    718  C2'  DT B   9      19.649   9.514 -10.300  1.00 26.53           C  
ATOM    719  C1'  DT B   9      19.747  10.059  -8.877  1.00 25.67           C  
ATOM    720  N1   DT B   9      20.844  11.046  -8.612  1.00 25.55           N  
ATOM    721  C2   DT B   9      20.497  12.358  -8.325  1.00 25.04           C  
ATOM    722  O2   DT B   9      19.353  12.784  -8.284  1.00 25.69           O  
ATOM    723  N3   DT B   9      21.543  13.197  -8.075  1.00 25.50           N  
ATOM    724  C4   DT B   9      22.888  12.869  -8.080  1.00 24.87           C  
ATOM    725  O4   DT B   9      23.746  13.714  -7.830  1.00 26.42           O  
ATOM    726  C5   DT B   9      23.190  11.489  -8.386  1.00 24.78           C  
ATOM    727  C7   DT B   9      24.614  11.087  -8.635  1.00 25.85           C  
ATOM    728  C6   DT B   9      22.173  10.641  -8.623  1.00 23.63           C  
ATOM    729  P    DT B  10      16.468   7.216 -10.132  1.00 30.29           P  
ATOM    730  OP1  DT B  10      16.558   6.340  -8.927  1.00 32.53           O  
ATOM    731  OP2  DT B  10      16.633   6.620 -11.483  1.00 30.67           O  
ATOM    732  O5'  DT B  10      15.083   8.013 -10.048  1.00 30.47           O  
ATOM    733  C5'  DT B  10      14.731   8.771  -8.874  1.00 30.39           C  
ATOM    734  C4'  DT B  10      13.406   9.492  -9.058  1.00 29.54           C  
ATOM    735  O4'  DT B  10      13.599  10.539 -10.047  1.00 28.56           O  
ATOM    736  C3'  DT B  10      12.253   8.627  -9.563  1.00 30.32           C  
ATOM    737  O3'  DT B  10      11.445   8.154  -8.482  1.00 33.69           O  
ATOM    738  C2'  DT B  10      11.459   9.563 -10.467  1.00 28.35           C  
ATOM    739  C1'  DT B  10      12.505  10.569 -10.942  1.00 25.31           C  
ATOM    740  N1   DT B  10      13.020  10.332 -12.343  1.00 23.32           N  
ATOM    741  C2   DT B  10      13.020  11.399 -13.223  1.00 23.63           C  
ATOM    742  O2   DT B  10      12.640  12.526 -12.937  1.00 23.22           O  
ATOM    743  N3   DT B  10      13.516  11.100 -14.474  1.00 21.66           N  
ATOM    744  C4   DT B  10      13.979   9.867 -14.913  1.00 23.02           C  
ATOM    745  O4   DT B  10      14.394   9.700 -16.054  1.00 20.18           O  
ATOM    746  C5   DT B  10      13.946   8.795 -13.944  1.00 22.61           C  
ATOM    747  C7   DT B  10      14.529   7.454 -14.283  1.00 22.80           C  
ATOM    748  C6   DT B  10      13.473   9.076 -12.719  1.00 23.28           C  
TER     749       DT B  10                                                      
HETATM  750  P   PO4 B  11      12.859  24.089  21.419  1.00 35.77           P  
HETATM  751  O1  PO4 B  11      11.397  23.986  21.072  1.00 36.40           O  
HETATM  752  O2  PO4 B  11      13.023  23.780  22.899  1.00 34.33           O  
HETATM  753  O3  PO4 B  11      13.590  23.048  20.604  1.00 36.23           O  
HETATM  754  O4  PO4 B  11      13.352  25.484  21.075  1.00 34.85           O  
HETATM  755  O   HOH A   1      29.873  21.007  29.241  1.00 39.18           O  
HETATM  756  O   HOH A   2      18.940   1.076  31.018  1.00 38.25           O  
HETATM  757  O   HOH A   3      28.482  21.180  31.481  0.50 20.88           O  
HETATM  758  O   HOH A   4      15.644  -5.590  17.289  1.00 24.95           O  
HETATM  759  O   HOH A   5      29.338  14.912  22.247  1.00 29.34           O  
HETATM  760  O   HOH A   6      30.577   6.605  27.603  1.00 33.06           O  
HETATM  761  O   HOH A   7       4.162  12.856  24.339  1.00 28.44           O  
HETATM  762  O   HOH A   8      20.437   7.927  13.394  1.00 29.76           O  
HETATM  763  O   HOH A   9      23.832  21.947  26.516  1.00 27.70           O  
HETATM  764  O   HOH A  10      28.518  24.176  19.063  1.00 25.96           O  
HETATM  765  O   HOH A  11      23.154   7.038  30.912  1.00 28.00           O  
HETATM  766  O   HOH A  12      30.292  18.531  29.525  1.00 41.65           O  
HETATM  767  O   HOH A  13      30.565  12.010  22.373  1.00 39.33           O  
HETATM  768  O   HOH A  14      26.447  22.572  27.285  1.00 32.23           O  
HETATM  769  O   HOH A  16      11.876   3.832  32.703  1.00 37.16           O  
HETATM  770  O   HOH A  17      28.012  15.289  12.449  1.00 28.92           O  
HETATM  771  O   HOH A  18       7.845  18.670  16.689  1.00 33.69           O  
HETATM  772  O   HOH A  19      23.843  24.001  18.129  1.00 37.14           O  
HETATM  773  O   HOH A  20      28.510  19.010  13.554  1.00 33.52           O  
HETATM  774  O   HOH A  21      12.055  22.480  27.660  1.00 22.05           O  
HETATM  775  O   HOH A  23      31.190   0.519  28.830  1.00 35.67           O  
HETATM  776  O   HOH A  24      28.821  20.777  26.899  1.00 23.54           O  
HETATM  777  O   HOH A  25      23.066   7.252  13.607  1.00 25.21           O  
HETATM  778  O   HOH A  26      22.017  19.797  37.617  1.00 25.69           O  
HETATM  779  O   HOH A  27      10.321  21.823  31.336  0.25 25.31           O  
HETATM  780  O   HOH A  28      29.119  11.790  35.311  1.00 49.51           O  
HETATM  781  O   HOH A  29      11.036  -1.792  22.520  1.00 22.09           O  
HETATM  782  O   HOH A  30       8.500  -1.433  23.350  1.00 33.70           O  
HETATM  783  O   HOH A  32      30.488  15.685  19.061  1.00 35.91           O  
HETATM  784  O   HOH A  33      19.831  22.110  29.975  1.00 11.86           O  
HETATM  785  O   HOH A  34       7.258  18.639  29.529  1.00 18.01           O  
HETATM  786  O   HOH A  35      26.750  17.274  19.054  1.00 17.51           O  
HETATM  787  O   HOH A  36      12.927  21.689  31.514  0.50 21.05           O  
HETATM  788  O   HOH A  37      19.398   8.103  15.778  1.00 21.15           O  
HETATM  789  O   HOH A  38      11.544   0.778  21.059  1.00 18.11           O  
HETATM  790  O   HOH A  39      25.505  16.574  21.310  1.00 14.20           O  
HETATM  791  O   HOH A  40       6.067   9.249  29.156  1.00 19.14           O  
HETATM  792  O   HOH A  41      22.256  21.467  28.829  1.00 12.49           O  
HETATM  793  O   HOH A  42       3.705  10.832  27.083  1.00 23.23           O  
HETATM  794  O   HOH A  43      23.884  21.720  31.643  0.50 14.96           O  
HETATM  795  O   HOH A  44      11.411   9.322  32.459  1.00 19.14           O  
HETATM  796  O   HOH A  45      12.715   7.401  34.227  1.00 24.52           O  
HETATM  797  O   HOH A  46      29.767   5.880  23.035  1.00 24.06           O  
HETATM  798  O   HOH A  47      29.732   9.280  21.502  1.00 25.27           O  
HETATM  799  O   HOH A  48      11.679  -3.922  20.787  1.00 25.69           O  
HETATM  800  O   HOH A  49      21.443   9.936  34.196  1.00 31.00           O  
HETATM  801  O   HOH A  50      26.745  14.863  23.490  1.00 21.34           O  
HETATM  802  O   HOH A  52      18.994  -2.467  19.763  1.00 40.80           O  
HETATM  803  O   HOH A  54      20.589  12.517  36.878  1.00 29.52           O  
HETATM  804  O   HOH A  57      27.136  16.079  33.112  1.00 48.43           O  
HETATM  805  O   HOH A  58      10.875   9.852  13.401  1.00 43.34           O  
HETATM  806  O   HOH A  59       9.680  11.858  15.498  1.00 43.19           O  
HETATM  807  O   HOH A  60      31.448  10.948  29.486  1.00 41.59           O  
HETATM  808  O   HOH A  61       8.023   3.295  26.742  1.00 42.03           O  
HETATM  809  O   HOH A  62      29.520   9.049  18.858  1.00 44.95           O  
HETATM  810  O   HOH A  63       8.468   6.065  26.181  1.00 31.19           O  
HETATM  811  O   HOH A  64      28.755   4.906  29.922  1.00 51.58           O  
HETATM  812  O   HOH A  65       2.832   6.610  22.474  1.00 40.13           O  
HETATM  813  O   HOH A  66      26.202  18.670  12.357  1.00 40.20           O  
HETATM  814  O   HOH A  67      17.482   6.991  34.301  1.00 44.58           O  
HETATM  815  O   HOH A  68       9.773   1.849  13.809  1.00 41.74           O  
HETATM  816  O   HOH A  69      28.192  14.742  35.191  1.00 44.27           O  
HETATM  817  O   HOH A  70      27.531   7.833  17.651  1.00 41.93           O  
HETATM  818  O   HOH A  71       8.861  -0.292  25.705  1.00 40.38           O  
HETATM  819  O   HOH A  72      10.321   2.267  31.336  0.50 42.53           O  
HETATM  820  O   HOH A  73      22.556   3.677   9.995  1.00 66.62           O  
HETATM  821  O   HOH A  74      12.892  -0.400  31.507  1.00 40.69           O  
HETATM  822  O   HOH A  75      24.011   4.847  31.989  1.00 40.38           O  
HETATM  823  O   HOH A  76       4.075  -0.749  19.719  1.00 53.12           O  
HETATM  824  O   HOH A  77      26.466   5.368  34.157  1.00 42.01           O  
HETATM  825  O   HOH A  78      21.580   6.132  32.642  1.00 45.18           O  
HETATM  826  O   HOH A  79       2.209   9.176  23.218  1.00 43.01           O  
HETATM  827  O   HOH A  80      18.746   8.924  35.754  1.00 35.74           O  
HETATM  828  O   HOH A  81      22.445   2.766  32.743  1.00 46.84           O  
HETATM  829  O   HOH A  82      23.322   2.027  13.662  1.00 46.71           O  
HETATM  830  O   HOH A  83       8.706  -2.643  27.845  1.00 48.18           O  
HETATM  831  O   HOH A  84      18.362  11.288  37.484  1.00 37.93           O  
HETATM  832  O   HOH A  86      30.542  22.130  25.364  0.50 23.64           O  
HETATM  833  O   HOH A  87      12.743   1.661  14.129  1.00 38.28           O  
HETATM  834  O   HOH A  88      10.907   6.870  11.986  1.00 45.58           O  
HETATM  835  O   HOH A  89      18.268   5.934  12.835  1.00 37.37           O  
HETATM  836  O   HOH A  92      23.547  17.601  38.862  1.00 59.66           O  
HETATM  837  O   HOH A  95      27.604  25.035  30.473  1.00 58.64           O  
HETATM  838  O   HOH A  96      26.308  22.643  30.379  1.00 34.18           O  
HETATM  839  O   HOH A  97      15.357  -3.752  15.115  1.00 47.82           O  
HETATM  840  O   HOH A  98      23.896  14.920  39.217  1.00 52.44           O  
HETATM  841  O   HOH A 100      32.857   9.972  22.338  1.00 52.28           O  
HETATM  842  O   HOH A 101      24.144  12.422  38.063  1.00 49.15           O  
HETATM  843  O   HOH A 102      26.178  24.952  16.102  1.00 55.00           O  
HETATM  844  O   HOH A 103      31.238  10.099  15.589  1.00 54.34           O  
HETATM  845  O   HOH A 104      31.018   8.121  13.995  1.00 49.70           O  
HETATM  846  O   HOH A 105      20.642   0.000  21.735  0.50 58.50           O  
HETATM  847  O   HOH A 107       8.812  13.842  11.557  1.00 45.13           O  
HETATM  848  O   HOH A 108       9.742   0.730  10.629  1.00 68.09           O  
HETATM  849  O   HOH A 109       9.244  -3.081  16.193  1.00 53.94           O  
HETATM  850  O   HOH A 110       7.898  -3.310  18.524  1.00 54.27           O  
HETATM  851  O   HOH A 111      35.752  11.584  21.748  1.00 48.45           O  
HETATM  852  O   HOH A 112       8.588   9.410   9.507  1.00 51.81           O  
HETATM  853  O   HOH A 113      23.846   9.930  35.700  1.00 53.31           O  
HETATM  854  O   HOH A 114      38.417  11.503  22.001  1.00 76.47           O  
HETATM  855  O   HOH A 116      14.806   0.263  32.990  1.00 41.92           O  
HETATM  856  O   HOH B  15      24.841  14.583  -0.762  1.00 44.54           O  
HETATM  857  O   HOH B  22      30.256  11.581  -4.732  1.00 44.34           O  
HETATM  858  O   HOH B  31      28.804   7.412  -5.919  1.00 46.99           O  
HETATM  859  O   HOH B  51      22.402  16.821  -3.322  1.00 49.77           O  
HETATM  860  O   HOH B  53      20.539   5.016   5.127  1.00 43.98           O  
HETATM  861  O   HOH B  55      20.600  15.603  -6.972  1.00 37.03           O  
HETATM  862  O   HOH B  56      30.339  12.991   9.119  1.00 44.07           O  
HETATM  863  O   HOH B  85      26.732   7.383 -10.381  1.00 49.65           O  
HETATM  864  O   HOH B  90      29.033  15.051   9.849  1.00 57.17           O  
HETATM  865  O   HOH B  91      19.286   4.633   0.247  1.00 60.29           O  
HETATM  866  O   HOH B  93      15.556  26.871  21.471  1.00 30.52           O  
HETATM  867  O   HOH B  94      10.321  21.822  20.667  0.50 29.97           O  
HETATM  868  O   HOH B  99      29.919   8.720  -3.576  1.00 49.17           O  
HETATM  869  O   HOH B 106      13.953  11.076  10.771  1.00 39.61           O  
HETATM  870  O   HOH B 115      27.467  14.758   3.222  1.00 43.73           O  
CONECT  750  751  752  753  754                                                 
CONECT  751  750                                                                
CONECT  752  750                                                                
CONECT  753  750                                                                
CONECT  754  750                                                                
MASTER      358    0    1    2    5    0    2    6  868    2    5    8          
END

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Related entries of code: 3d2w

Entries with 90% protein sequence similarity cutoff in PDBbind
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Complexes with the same small molecule ligand
PDB Code	Check Database	Ligand Name
3glf	RCSB PDB PDBbind	10-mer
3i5x	RCSB PDB PDBbind	10-mer
3k49	RCSB PDB PDBbind	10-mer
3k4e	RCSB PDB PDBbind	10-mer
3kde	RCSB PDB PDBbind	10-mer
3kjo	RCSB PDB PDBbind	10-mer
5ho4	RCSB PDB PDBbind	10-mer
5zva	RCSB PDB PDBbind	10-mer
6kbs	RCSB PDB PDBbind	10-mer
6iir	RCSB PDB PDBbind	10-mer
5zc9	RCSB PDB PDBbind	10-mer

Entry Information

PDB ID	3d2w
Complex Type	Protein-Nucleic Acid
PDBbind Subset	general set
Protein Name	mouse TAR DNA-binding protein 43(TDP-43) RRM2 domain
Ligand Name	10-mer
EC.Number	E.C.-.-.-.-
Resolution	1.65(Å)
Affinity (Kd/Ki/IC50)	Kd=137.5nM
Release Year	2009
Protein/NA Sequence	Check fasta file
Primary Reference	(2009) Nucleic Acids Res. Vol. 37: pp. 1799-1808

Links to External Databases

RCSB PDB	The mother database
PDBsum	Enhanced annotations on PDB entries
Pubchem	Comprehensive collection of chemical and biological data
UniProtKB AC	UniProt accession number (AC): Q921F2
Entrez Gene ID	NCBI Entrez Gene ID: 230908
ASD	Information of known allosteric effects of PDB entries

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