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Browse entries in the PDBbind-CN Database

HEADER    RNA BINDING PROTEIN/RNA                 19-JAN-16   5HO4              
TITLE     CRYSTAL STRUCTURE OF HNRNPA2B1 IN COMPLEX WITH 10-MER RNA             
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS A2/B1;            
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: UNP RESIDUES 15-193;                                       
COMPND   5 SYNONYM: HNRNP A2/B1;                                                
COMPND   6 ENGINEERED: YES;                                                     
COMPND   7 MOL_ID: 2;                                                           
COMPND   8 MOLECULE: RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3');              
COMPND   9 CHAIN: B;                                                            
COMPND  10 ENGINEERED: YES                                                      
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 SYNTHETIC: YES;                                                      
SOURCE   3 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   4 ORGANISM_COMMON: HUMAN;                                              
SOURCE   5 ORGANISM_TAXID: 9606;                                                
SOURCE   6 MOL_ID: 2;                                                           
SOURCE   7 SYNTHETIC: YES;                                                      
SOURCE   8 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT;                            
SOURCE   9 ORGANISM_TAXID: 32630                                                
KEYWDS    HNRNPA2B1, RRMS, RNA BINDING PROTEIN-RNA COMPLEX                      
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    B.X.WU,S.C.SU,J.H.GAN,J.B.MA                                          
REVDAT   4   22-MAY-19 5HO4    1       TITLE  JRNL                              
REVDAT   3   07-FEB-18 5HO4    1       JRNL                                     
REVDAT   2   01-MAR-17 5HO4    1       TITLE                                    
REVDAT   1   08-FEB-17 5HO4    0                                                
JRNL        AUTH   B.X.WU,S.C.SU,D.P.PATIL,H.LIU,J.H.GAN,S.R.JAFFREY,J.B.MA     
JRNL        TITL   MOLECULAR BASIS FOR THE SPECIFIC AND MULTIVARIANT            
JRNL        TITL 2 RECOGNITIONS OF RNA SUBSTRATES BY HUMAN HNRNP A2/B1.         
JRNL        REF    NAT COMMUN                    V.   9   420 2018              
JRNL        REFN                   ESSN 2041-1723                               
JRNL        PMID   29379020                                                     
JRNL        DOI    10.1038/S41467-017-02770-Z                                   
REMARK   2                                                                      
REMARK   2 RESOLUTION.    1.85 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.8.0103                                      
REMARK   3   AUTHORS     : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,STEINER,              
REMARK   3               : NICHOLLS,WINN,LONG,VAGIN                             
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : NULL                                          
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.85                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 30.00                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : NULL                           
REMARK   3   COMPLETENESS FOR RANGE        (%) : 92.4                           
REMARK   3   NUMBER OF REFLECTIONS             : 20208                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.185                           
REMARK   3   R VALUE            (WORKING SET) : 0.183                           
REMARK   3   FREE R VALUE                     : 0.220                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 5.200                           
REMARK   3   FREE R VALUE TEST SET COUNT      : 1103                            
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 1.85                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 1.90                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 845                          
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 52.12                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.2470                       
REMARK   3   BIN FREE R VALUE SET COUNT          : 40                           
REMARK   3   BIN FREE R VALUE                    : 0.2860                       
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 1444                                    
REMARK   3   NUCLEIC ACID ATOMS       : 193                                     
REMARK   3   HETEROGEN ATOMS          : 0                                       
REMARK   3   SOLVENT ATOMS            : 132                                     
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 23.57                          
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : 0.09000                                              
REMARK   3    B22 (A**2) : -0.22000                                             
REMARK   3    B33 (A**2) : 0.13000                                              
REMARK   3    B12 (A**2) : 0.00000                                              
REMARK   3    B13 (A**2) : -0.06000                                             
REMARK   3    B23 (A**2) : 0.00000                                              
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): 0.131         
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.127         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): 0.092         
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 3.117         
REMARK   3                                                                      
REMARK   3 CORRELATION COEFFICIENTS.                                            
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.953                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.929                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):  1716 ; 0.018 ; 0.018       
REMARK   3   BOND LENGTHS OTHERS               (A):  1517 ; 0.002 ; 0.020       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  2345 ; 1.961 ; 1.847       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  3507 ; 1.491 ; 3.000       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):   183 ; 6.260 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):    78 ;37.696 ;22.821       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):   281 ;14.073 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):    16 ;15.422 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   242 ; 0.136 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):  1797 ; 0.011 ; 0.020       
REMARK   3   GENERAL PLANES OTHERS             (A):   409 ; 0.002 ; 0.020       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):   727 ; 2.189 ; 2.001       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):   726 ; 2.176 ; 1.997       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):   910 ; 3.238 ; 2.980       
REMARK   3   MAIN-CHAIN ANGLE OTHER ATOMS   (A**2):   911 ; 3.240 ; 2.985       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):   989 ; 3.151 ; 2.550       
REMARK   3   SIDE-CHAIN BOND OTHER ATOMS    (A**2):   989 ; 3.151 ; 2.550       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE OTHER ATOMS   (A**2):  1435 ; 4.902 ; 3.690       
REMARK   3   LONG RANGE B REFINED ATOMS     (A**2):  2055 ; 7.279 ;18.769       
REMARK   3   LONG RANGE B OTHER ATOMS       (A**2):  2004 ; 7.108 ;18.369       
REMARK   3                                                                      
REMARK   3 ANISOTROPIC THERMAL FACTOR RESTRAINTS.    COUNT   RMS   WEIGHT       
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : NULL                                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : NULL                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.20                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING   
REMARK   3  POSITIONS                                                           
REMARK   4                                                                      
REMARK   4 5HO4 COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBJ ON 21-JAN-16.                  
REMARK 100 THE DEPOSITION ID IS D_1000217410.                                   
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 06-DEC-15                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : NULL                               
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : SSRF                               
REMARK 200  BEAMLINE                       : BL18U1                             
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.987                              
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : RIGAKU                             
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : D*TREK                             
REMARK 200  DATA SCALING SOFTWARE          : NULL                               
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 21311                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.850                              
REMARK 200  RESOLUTION RANGE LOW       (A) : 63.170                             
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : NULL                               
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 92.4                               
REMARK 200  DATA REDUNDANCY                : 2.900                              
REMARK 200  R MERGE                    (I) : NULL                               
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 18.4000                            
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : NULL                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : NULL                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : NULL                               
REMARK 200  DATA REDUNDANCY IN SHELL       : NULL                               
REMARK 200  R MERGE FOR SHELL          (I) : NULL                               
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : NULL                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: NULL                         
REMARK 200 SOFTWARE USED: PHASER                                                
REMARK 200 STARTING MODEL: NULL                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NULL                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 56.67                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.84                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 0.2M TRI-SODIUM CITRATE, 20% (W/V)       
REMARK 280  POLYETHYLENE GLYCOL 3,350, VAPOR DIFFUSION, HANGING DROP,           
REMARK 280  TEMPERATURE 293K                                                    
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: C 1 2 1                          
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,Y,-Z                                                 
REMARK 290       3555   X+1/2,Y+1/2,Z                                           
REMARK 290       4555   -X+1/2,Y+1/2,-Z                                         
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   3  1.000000  0.000000  0.000000       54.80200            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000       19.47950            
REMARK 290   SMTRY3   3  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   4 -1.000000  0.000000  0.000000       54.80200            
REMARK 290   SMTRY2   4  0.000000  1.000000  0.000000       19.47950            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: DIMERIC                           
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B                                  
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 470                                                                      
REMARK 470 MISSING ATOM                                                         
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;           
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;          
REMARK 470 I=INSERTION CODE):                                                   
REMARK 470   M RES CSSEQI  ATOMS                                                
REMARK 470       C B   6    N1   C2   O2   N3   C4   N4   C5                    
REMARK 470       C B   6    C6                                                  
REMARK 470       C B  10    C3'  O3'  C2'  O2'  C1'  N1   C2                    
REMARK 470       C B  10    O2   N3   C4   N4   C5   C6                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT                     
REMARK 500                                                                      
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.                            
REMARK 500                                                                      
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE          
REMARK 500   O    HOH B   103     O    HOH B   116              1.80            
REMARK 500   O    HOH B   101     O    HOH B   117              2.07            
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES                                       
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)              
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3                                     
REMARK 500    ARG A  21   NE  -  CZ  -  NH1 ANGL. DEV. =   5.2 DEGREES          
REMARK 500    ARG A  21   NE  -  CZ  -  NH2 ANGL. DEV. =  -3.2 DEGREES          
REMARK 500    ARG A  54   NE  -  CZ  -  NH1 ANGL. DEV. =  -3.8 DEGREES          
REMARK 500    ARG A  95   NE  -  CZ  -  NH1 ANGL. DEV. =   3.6 DEGREES          
REMARK 500    ARG A 153   NE  -  CZ  -  NH2 ANGL. DEV. =  -3.2 DEGREES          
REMARK 500      A B   1   C5' -  C4' -  O4' ANGL. DEV. =   6.0 DEGREES          
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    LYS A 120     -146.07     52.39                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
DBREF  5HO4 A   15   193  UNP    P22626   ROA2_HUMAN      15    193             
DBREF  5HO4 B    1    10  PDB    5HO4     5HO4             1     10             
SEQRES   1 A  179  ARG GLU LYS GLU GLN PHE ARG LYS LEU PHE ILE GLY GLY          
SEQRES   2 A  179  LEU SER PHE GLU THR THR GLU GLU SER LEU ARG ASN TYR          
SEQRES   3 A  179  TYR GLU GLN TRP GLY LYS LEU THR ASP CYS VAL VAL MET          
SEQRES   4 A  179  ARG ASP PRO ALA SER LYS ARG SER ARG GLY PHE GLY PHE          
SEQRES   5 A  179  VAL THR PHE SER SER MET ALA GLU VAL ASP ALA ALA MET          
SEQRES   6 A  179  ALA ALA ARG PRO HIS SER ILE ASP GLY ARG VAL VAL GLU          
SEQRES   7 A  179  PRO LYS ARG ALA VAL ALA ARG GLU GLU SER GLY LYS PRO          
SEQRES   8 A  179  GLY ALA HIS VAL THR VAL LYS LYS LEU PHE VAL GLY GLY          
SEQRES   9 A  179  ILE LYS GLU ASP THR GLU GLU HIS HIS LEU ARG ASP TYR          
SEQRES  10 A  179  PHE GLU GLU TYR GLY LYS ILE ASP THR ILE GLU ILE ILE          
SEQRES  11 A  179  THR ASP ARG GLN SER GLY LYS LYS ARG GLY PHE GLY PHE          
SEQRES  12 A  179  VAL THR PHE ASP ASP HIS ASP PRO VAL ASP LYS ILE VAL          
SEQRES  13 A  179  LEU GLN LYS TYR HIS THR ILE ASN GLY HIS ASN ALA GLU          
SEQRES  14 A  179  VAL ARG LYS ALA LEU SER ARG GLN GLU MET                      
SEQRES   1 B   10    A   A   G   G   A   C   U   A   G   C                      
FORMUL   3  HOH   *132(H2 O)                                                    
HELIX    1 AA1 LYS A   17  PHE A   20  5                                   4    
HELIX    2 AA2 THR A   33  GLU A   42  1                                  10    
HELIX    3 AA3 GLN A   43  GLY A   45  5                                   3    
HELIX    4 AA4 SER A   71  ALA A   81  1                                  11    
HELIX    5 AA5 ALA A   98  SER A  102  5                                   5    
HELIX    6 AA6 GLU A  124  GLU A  133  1                                  10    
HELIX    7 AA7 GLU A  134  GLY A  136  5                                   3    
HELIX    8 AA8 HIS A  163  VAL A  170  1                                   8    
SHEET    1 AA1 4 LEU A  47  ARG A  54  0                                        
SHEET    2 AA1 4 SER A  61  PHE A  69 -1  O  ARG A  62   N  MET A  53           
SHEET    3 AA1 4 LYS A  22  GLY A  26 -1  N  ILE A  25   O  GLY A  65           
SHEET    4 AA1 4 GLU A  92  ARG A  95 -1  O  LYS A  94   N  PHE A  24           
SHEET    1 AA2 2 SER A  85  ILE A  86  0                                        
SHEET    2 AA2 2 ARG A  89  VAL A  90 -1  O  ARG A  89   N  ILE A  86           
SHEET    1 AA3 5 ILE A 138  THR A 145  0                                        
SHEET    2 AA3 5 LYS A 152  PHE A 160 -1  O  THR A 159   N  THR A 140           
SHEET    3 AA3 5 LYS A 113  GLY A 117 -1  N  LEU A 114   O  VAL A 158           
SHEET    4 AA3 5 HIS A 180  LYS A 186 -1  O  GLU A 183   N  GLY A 117           
SHEET    5 AA3 5 TYR A 174  ILE A 177 -1  N  ILE A 177   O  HIS A 180           
CISPEP   1 ARG A   82    PRO A   83          0         0.71                     
CRYST1  109.604   38.959   70.442  90.00 116.26  90.00 C 1 2 1       4          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.009124  0.000000  0.004502        0.00000                         
SCALE2      0.000000  0.025668  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.015830        0.00000                         
ATOM      1  N   ARG A  15     -10.377  -3.659   0.354  1.00 50.98           N  
ATOM      2  CA  ARG A  15     -10.792  -2.668   1.408  1.00 48.76           C  
ATOM      3  C   ARG A  15     -12.240  -2.176   1.206  1.00 45.83           C  
ATOM      4  O   ARG A  15     -12.738  -2.112   0.112  1.00 47.12           O  
ATOM      5  CB  ARG A  15      -9.844  -1.475   1.470  1.00 53.65           C  
ATOM      6  CG  ARG A  15     -10.094  -0.571   2.675  1.00 53.92           C  
ATOM      7  CD  ARG A  15      -8.967   0.428   2.874  1.00 55.65           C  
ATOM      8  NE  ARG A  15      -7.919  -0.039   3.783  1.00 53.14           N  
ATOM      9  CZ  ARG A  15      -6.764   0.611   4.006  1.00 51.63           C  
ATOM     10  NH1 ARG A  15      -6.482   1.766   3.393  1.00 48.42           N  
ATOM     11  NH2 ARG A  15      -5.871   0.108   4.849  1.00 48.48           N  
ATOM     12  N   GLU A  16     -12.895  -1.849   2.299  1.00 35.99           N  
ATOM     13  CA  GLU A  16     -14.298  -1.536   2.307  1.00 30.64           C  
ATOM     14  C   GLU A  16     -14.489  -0.023   2.142  1.00 23.65           C  
ATOM     15  O   GLU A  16     -13.546   0.751   2.285  1.00 22.61           O  
ATOM     16  CB  GLU A  16     -14.821  -2.064   3.610  1.00 30.83           C  
ATOM     17  CG  GLU A  16     -14.497  -3.577   3.743  1.00 34.81           C  
ATOM     18  CD  GLU A  16     -14.257  -4.061   5.171  1.00 36.67           C  
ATOM     19  OE1 GLU A  16     -13.417  -3.491   5.843  1.00 35.08           O  
ATOM     20  OE2 GLU A  16     -14.905  -5.021   5.610  1.00 34.89           O  
ATOM     21  N   LYS A  17     -15.705   0.372   1.807  1.00 20.96           N  
ATOM     22  CA  LYS A  17     -16.045   1.771   1.676  1.00 20.38           C  
ATOM     23  C   LYS A  17     -15.778   2.525   2.969  1.00 17.49           C  
ATOM     24  O   LYS A  17     -16.033   2.028   4.046  1.00 18.95           O  
ATOM     25  CB  LYS A  17     -17.494   1.909   1.285  1.00 22.47           C  
ATOM     26  CG  LYS A  17     -17.688   1.551  -0.168  1.00 28.46           C  
ATOM     27  CD  LYS A  17     -19.166   1.529  -0.505  1.00 33.51           C  
ATOM     28  CE  LYS A  17     -19.315   1.931  -1.964  1.00 41.49           C  
ATOM     29  NZ  LYS A  17     -20.641   1.554  -2.535  1.00 46.42           N  
ATOM     30  N   GLU A  18     -15.282   3.742   2.833  1.00 16.52           N  
ATOM     31  CA  GLU A  18     -14.899   4.545   3.963  1.00 18.20           C  
ATOM     32  C   GLU A  18     -16.065   4.792   4.911  1.00 16.88           C  
ATOM     33  O   GLU A  18     -15.884   4.648   6.096  1.00 14.79           O  
ATOM     34  CB  GLU A  18     -14.251   5.830   3.462  1.00 20.96           C  
ATOM     35  CG  GLU A  18     -13.699   6.706   4.526  1.00 26.07           C  
ATOM     36  CD  GLU A  18     -13.116   7.959   3.916  1.00 26.88           C  
ATOM     37  OE1 GLU A  18     -13.852   8.714   3.268  1.00 33.40           O  
ATOM     38  OE2 GLU A  18     -11.922   8.126   4.015  1.00 36.38           O  
ATOM     39  N   GLN A  19     -17.272   5.035   4.394  1.00 18.52           N  
ATOM     40  CA  GLN A  19     -18.428   5.219   5.287  1.00 20.79           C  
ATOM     41  C   GLN A  19     -18.691   4.054   6.262  1.00 20.35           C  
ATOM     42  O   GLN A  19     -19.142   4.297   7.415  1.00 24.10           O  
ATOM     43  CB  GLN A  19     -19.709   5.646   4.580  1.00 22.73           C  
ATOM     44  CG  GLN A  19     -20.605   6.579   5.473  1.00 27.16           C  
ATOM     45  CD  GLN A  19     -19.998   8.012   5.898  1.00 26.01           C  
ATOM     46  OE1 GLN A  19     -19.578   8.797   5.102  1.00 31.20           O  
ATOM     47  NE2 GLN A  19     -20.069   8.316   7.127  1.00 25.30           N  
ATOM     48  N   PHE A  20     -18.338   2.861   5.839  1.00 18.10           N  
ATOM     49  CA  PHE A  20     -18.489   1.676   6.644  1.00 15.73           C  
ATOM     50  C   PHE A  20     -17.368   1.459   7.695  1.00 13.67           C  
ATOM     51  O   PHE A  20     -17.438   0.555   8.447  1.00 14.34           O  
ATOM     52  CB  PHE A  20     -18.610   0.465   5.741  1.00 20.72           C  
ATOM     53  CG  PHE A  20     -19.888   0.435   4.916  1.00 23.63           C  
ATOM     54  CD1 PHE A  20     -20.822   1.403   5.027  1.00 29.98           C  
ATOM     55  CD2 PHE A  20     -20.131  -0.576   4.056  1.00 34.10           C  
ATOM     56  CE1 PHE A  20     -21.993   1.368   4.283  1.00 31.73           C  
ATOM     57  CE2 PHE A  20     -21.311  -0.622   3.334  1.00 36.03           C  
ATOM     58  CZ  PHE A  20     -22.232   0.353   3.459  1.00 30.25           C  
ATOM     59  N   ARG A  21     -16.363   2.309   7.674  1.00 12.27           N  
ATOM     60  CA  ARG A  21     -15.192   2.243   8.566  1.00 13.25           C  
ATOM     61  C   ARG A  21     -15.058   3.398   9.565  1.00 11.48           C  
ATOM     62  O   ARG A  21     -14.090   3.466  10.310  1.00 11.25           O  
ATOM     63  CB  ARG A  21     -13.936   2.183   7.681  1.00 15.70           C  
ATOM     64  CG  ARG A  21     -13.928   0.883   6.929  1.00 18.23           C  
ATOM     65  CD  ARG A  21     -12.655   0.602   6.246  1.00 21.56           C  
ATOM     66  NE  ARG A  21     -12.526   1.317   5.046  1.00 23.80           N  
ATOM     67  CZ  ARG A  21     -11.667   2.316   4.762  1.00 22.56           C  
ATOM     68  NH1 ARG A  21     -10.780   2.805   5.580  1.00 23.81           N  
ATOM     69  NH2 ARG A  21     -11.723   2.828   3.551  1.00 22.08           N  
ATOM     70  N   LYS A  22     -16.027   4.315   9.543  1.00 10.59           N  
ATOM     71  CA  LYS A  22     -15.917   5.595  10.151  1.00  9.87           C  
ATOM     72  C   LYS A  22     -16.826   5.707  11.367  1.00  9.37           C  
ATOM     73  O   LYS A  22     -18.015   5.398  11.283  1.00  8.01           O  
ATOM     74  CB  LYS A  22     -16.210   6.709   9.139  1.00 10.49           C  
ATOM     75  CG  LYS A  22     -15.816   8.109   9.628  1.00 11.08           C  
ATOM     76  CD  LYS A  22     -15.913   9.101   8.422  1.00 12.86           C  
ATOM     77  CE  LYS A  22     -14.953  10.259   8.480  1.00 15.18           C  
ATOM     78  NZ  LYS A  22     -15.135  11.159   7.290  1.00 14.06           N  
ATOM     79  N   LEU A  23     -16.273   6.221  12.469  1.00  8.87           N  
ATOM     80  CA  LEU A  23     -17.037   6.608  13.593  1.00  9.05           C  
ATOM     81  C   LEU A  23     -17.000   8.121  13.831  1.00  9.48           C  
ATOM     82  O   LEU A  23     -15.889   8.721  13.756  1.00  9.39           O  
ATOM     83  CB  LEU A  23     -16.496   5.951  14.819  1.00 10.04           C  
ATOM     84  CG  LEU A  23     -16.633   4.417  14.904  1.00 10.93           C  
ATOM     85  CD1 LEU A  23     -15.851   3.941  16.093  1.00 11.87           C  
ATOM     86  CD2 LEU A  23     -18.082   3.981  15.079  1.00 11.71           C  
ATOM     87  N   PHE A  24     -18.142   8.675  14.208  1.00  9.02           N  
ATOM     88  CA  PHE A  24     -18.293  10.005  14.836  1.00  9.93           C  
ATOM     89  C   PHE A  24     -18.012   9.809  16.321  1.00 10.78           C  
ATOM     90  O   PHE A  24     -18.527   8.854  16.947  1.00 10.39           O  
ATOM     91  CB  PHE A  24     -19.740  10.541  14.651  1.00 10.28           C  
ATOM     92  CG  PHE A  24     -20.047  11.773  15.412  1.00 11.70           C  
ATOM     93  CD1 PHE A  24     -19.831  13.036  14.862  1.00 12.82           C  
ATOM     94  CD2 PHE A  24     -20.648  11.687  16.671  1.00 12.30           C  
ATOM     95  CE1 PHE A  24     -20.149  14.166  15.578  1.00 12.65           C  
ATOM     96  CE2 PHE A  24     -20.935  12.804  17.387  1.00 13.14           C  
ATOM     97  CZ  PHE A  24     -20.650  14.057  16.838  1.00 13.67           C  
ATOM     98  N   ILE A  25     -17.205  10.697  16.893  1.00 11.04           N  
ATOM     99  CA  ILE A  25     -16.856  10.595  18.319  1.00 10.87           C  
ATOM    100  C   ILE A  25     -17.298  11.933  18.976  1.00 11.26           C  
ATOM    101  O   ILE A  25     -16.690  12.969  18.748  1.00 11.14           O  
ATOM    102  CB  ILE A  25     -15.359  10.327  18.563  1.00 11.05           C  
ATOM    103  CG1 ILE A  25     -14.755   9.198  17.704  1.00 10.74           C  
ATOM    104  CG2 ILE A  25     -15.086  10.034  20.004  1.00 11.33           C  
ATOM    105  CD1 ILE A  25     -15.383   7.824  17.952  1.00 10.57           C  
ATOM    106  N   GLY A  26     -18.380  11.871  19.753  1.00 11.37           N  
ATOM    107  CA  GLY A  26     -19.013  13.018  20.389  1.00 12.70           C  
ATOM    108  C   GLY A  26     -18.581  13.186  21.841  1.00 13.45           C  
ATOM    109  O   GLY A  26     -18.083  12.241  22.475  1.00 15.04           O  
ATOM    110  N   GLY A  27     -18.639  14.411  22.328  1.00 14.18           N  
ATOM    111  CA  GLY A  27     -18.338  14.671  23.764  1.00 15.48           C  
ATOM    112  C   GLY A  27     -16.893  14.551  24.194  1.00 14.99           C  
ATOM    113  O   GLY A  27     -16.593  14.165  25.309  1.00 17.52           O  
ATOM    114  N   LEU A  28     -15.994  14.893  23.282  1.00 16.15           N  
ATOM    115  CA  LEU A  28     -14.624  15.015  23.574  1.00 15.54           C  
ATOM    116  C   LEU A  28     -14.415  16.152  24.562  1.00 19.07           C  
ATOM    117  O   LEU A  28     -15.025  17.229  24.443  1.00 16.99           O  
ATOM    118  CB  LEU A  28     -13.802  15.322  22.325  1.00 15.74           C  
ATOM    119  CG  LEU A  28     -13.883  14.273  21.177  1.00 15.48           C  
ATOM    120  CD1 LEU A  28     -13.022  14.686  20.041  1.00 16.58           C  
ATOM    121  CD2 LEU A  28     -13.508  12.930  21.679  1.00 15.72           C  
ATOM    122  N   SER A  29     -13.444  15.923  25.439  1.00 18.70           N  
ATOM    123  CA  SER A  29     -12.847  17.026  26.182  1.00 20.16           C  
ATOM    124  C   SER A  29     -12.245  18.023  25.203  1.00 20.22           C  
ATOM    125  O   SER A  29     -11.662  17.649  24.189  1.00 17.48           O  
ATOM    126  CB  SER A  29     -11.749  16.523  27.087  1.00 22.53           C  
ATOM    127  OG  SER A  29     -11.100  17.637  27.588  1.00 22.01           O  
ATOM    128  N   PHE A  30     -12.297  19.301  25.552  1.00 22.73           N  
ATOM    129  CA  PHE A  30     -11.664  20.348  24.733  1.00 27.18           C  
ATOM    130  C   PHE A  30     -10.178  20.222  24.708  1.00 24.89           C  
ATOM    131  O   PHE A  30      -9.549  20.741  23.826  1.00 24.45           O  
ATOM    132  CB  PHE A  30     -12.164  21.753  25.139  1.00 34.73           C  
ATOM    133  CG  PHE A  30     -13.658  21.889  24.997  1.00 39.19           C  
ATOM    134  CD1 PHE A  30     -14.284  21.581  23.780  1.00 42.80           C  
ATOM    135  CD2 PHE A  30     -14.458  22.232  26.083  1.00 45.53           C  
ATOM    136  CE1 PHE A  30     -15.647  21.638  23.639  1.00 43.01           C  
ATOM    137  CE2 PHE A  30     -15.836  22.303  25.937  1.00 48.89           C  
ATOM    138  CZ  PHE A  30     -16.427  22.012  24.711  1.00 49.30           C  
ATOM    139  N   GLU A  31      -9.614  19.476  25.643  1.00 23.77           N  
ATOM    140  CA  GLU A  31      -8.188  19.121  25.629  1.00 25.07           C  
ATOM    141  C   GLU A  31      -7.778  18.058  24.661  1.00 19.52           C  
ATOM    142  O   GLU A  31      -6.596  17.913  24.377  1.00 20.66           O  
ATOM    143  CB  GLU A  31      -7.732  18.529  27.004  1.00 29.39           C  
ATOM    144  CG  GLU A  31      -8.158  19.268  28.266  1.00 35.93           C  
ATOM    145  CD  GLU A  31      -7.928  20.734  28.158  1.00 43.67           C  
ATOM    146  OE1 GLU A  31      -8.800  21.511  28.667  1.00 55.43           O  
ATOM    147  OE2 GLU A  31      -6.885  21.081  27.537  1.00 43.95           O  
ATOM    148  N   THR A  32      -8.688  17.195  24.265  1.00 16.62           N  
ATOM    149  CA  THR A  32      -8.317  16.041  23.395  1.00 17.09           C  
ATOM    150  C   THR A  32      -7.802  16.473  22.041  1.00 16.79           C  
ATOM    151  O   THR A  32      -8.448  17.252  21.348  1.00 18.78           O  
ATOM    152  CB  THR A  32      -9.513  15.065  23.248  1.00 18.41           C  
ATOM    153  OG1 THR A  32      -9.840  14.477  24.537  1.00 19.22           O  
ATOM    154  CG2 THR A  32      -9.279  13.995  22.194  1.00 17.45           C  
ATOM    155  N   THR A  33      -6.695  15.886  21.623  1.00 18.93           N  
ATOM    156  CA  THR A  33      -6.067  16.171  20.358  1.00 20.86           C  
ATOM    157  C   THR A  33      -6.170  14.971  19.435  1.00 19.30           C  
ATOM    158  O   THR A  33      -6.498  13.864  19.892  1.00 19.10           O  
ATOM    159  CB  THR A  33      -4.555  16.445  20.596  1.00 21.73           C  
ATOM    160  OG1 THR A  33      -4.026  15.302  21.289  1.00 21.48           O  
ATOM    161  CG2 THR A  33      -4.306  17.767  21.401  1.00 23.05           C  
ATOM    162  N   GLU A  34      -5.763  15.154  18.176  1.00 18.23           N  
ATOM    163  CA  GLU A  34      -5.741  14.039  17.186  1.00 20.04           C  
ATOM    164  C   GLU A  34      -4.808  12.955  17.614  1.00 22.22           C  
ATOM    165  O   GLU A  34      -5.112  11.778  17.535  1.00 19.18           O  
ATOM    166  CB  GLU A  34      -5.504  14.549  15.726  1.00 21.77           C  
ATOM    167  CG  GLU A  34      -6.646  15.500  15.333  1.00 24.84           C  
ATOM    168  CD  GLU A  34      -6.423  16.474  14.223  1.00 27.44           C  
ATOM    169  OE1 GLU A  34      -7.426  16.972  13.691  1.00 25.38           O  
ATOM    170  OE2 GLU A  34      -5.280  16.739  13.788  1.00 35.80           O  
ATOM    171  N   GLU A  35      -3.672  13.331  18.205  1.00 26.59           N  
ATOM    172  CA  GLU A  35      -2.732  12.294  18.784  1.00 25.98           C  
ATOM    173  C   GLU A  35      -3.336  11.426  19.888  1.00 23.11           C  
ATOM    174  O   GLU A  35      -3.158  10.157  19.908  1.00 21.53           O  
ATOM    175  CB  GLU A  35      -1.317  12.894  19.218  1.00 32.49           C  
ATOM    176  CG  GLU A  35      -1.257  14.387  19.572  1.00 40.53           C  
ATOM    177  CD  GLU A  35      -1.173  15.396  18.384  1.00 47.35           C  
ATOM    178  OE1 GLU A  35      -0.061  15.576  17.825  1.00 56.13           O  
ATOM    179  OE2 GLU A  35      -2.202  16.076  18.038  1.00 41.25           O  
ATOM    180  N   SER A  36      -4.046  12.046  20.828  1.00 20.53           N  
ATOM    181  CA  SER A  36      -4.678  11.304  21.928  1.00 21.47           C  
ATOM    182  C   SER A  36      -5.941  10.477  21.497  1.00 19.20           C  
ATOM    183  O   SER A  36      -6.154   9.368  21.970  1.00 19.13           O  
ATOM    184  CB  SER A  36      -4.970  12.207  23.139  1.00 22.72           C  
ATOM    185  OG  SER A  36      -6.158  12.966  23.046  1.00 27.12           O  
ATOM    186  N   LEU A  37      -6.749  11.042  20.633  1.00 17.93           N  
ATOM    187  CA  LEU A  37      -7.825  10.280  19.939  1.00 17.92           C  
ATOM    188  C   LEU A  37      -7.278   9.080  19.110  1.00 18.62           C  
ATOM    189  O   LEU A  37      -7.782   7.952  19.230  1.00 18.58           O  
ATOM    190  CB  LEU A  37      -8.609  11.260  19.101  1.00 17.42           C  
ATOM    191  CG  LEU A  37      -9.870  10.789  18.395  1.00 16.47           C  
ATOM    192  CD1 LEU A  37     -10.920  10.349  19.413  1.00 16.25           C  
ATOM    193  CD2 LEU A  37     -10.396  11.857  17.447  1.00 16.55           C  
ATOM    194  N   ARG A  38      -6.219   9.317  18.313  1.00 21.24           N  
ATOM    195  CA  ARG A  38      -5.551   8.262  17.515  1.00 22.79           C  
ATOM    196  C   ARG A  38      -4.967   7.172  18.392  1.00 24.38           C  
ATOM    197  O   ARG A  38      -5.257   5.966  18.208  1.00 24.22           O  
ATOM    198  CB  ARG A  38      -4.460   8.886  16.572  1.00 24.92           C  
ATOM    199  CG  ARG A  38      -3.581   7.930  15.746  1.00 25.09           C  
ATOM    200  CD  ARG A  38      -2.795   8.670  14.647  1.00 23.43           C  
ATOM    201  NE  ARG A  38      -3.538   8.903  13.400  1.00 24.42           N  
ATOM    202  CZ  ARG A  38      -3.798   7.987  12.451  1.00 24.15           C  
ATOM    203  NH1 ARG A  38      -3.384   6.701  12.562  1.00 24.28           N  
ATOM    204  NH2 ARG A  38      -4.489   8.327  11.355  1.00 22.07           N  
ATOM    205  N   ASN A  39      -4.179   7.580  19.382  1.00 25.40           N  
ATOM    206  CA  ASN A  39      -3.653   6.633  20.386  1.00 27.32           C  
ATOM    207  C   ASN A  39      -4.701   5.738  21.031  1.00 26.88           C  
ATOM    208  O   ASN A  39      -4.484   4.527  21.209  1.00 25.85           O  
ATOM    209  CB  ASN A  39      -2.903   7.404  21.483  1.00 33.70           C  
ATOM    210  CG  ASN A  39      -1.915   6.552  22.241  1.00 41.05           C  
ATOM    211  OD1 ASN A  39      -0.827   6.302  21.761  1.00 52.27           O  
ATOM    212  ND2 ASN A  39      -2.274   6.140  23.452  1.00 43.16           N  
ATOM    213  N   TYR A  40      -5.848   6.323  21.403  1.00 21.29           N  
ATOM    214  CA  TYR A  40      -6.901   5.584  22.038  1.00 19.29           C  
ATOM    215  C   TYR A  40      -7.530   4.578  21.083  1.00 18.47           C  
ATOM    216  O   TYR A  40      -7.616   3.374  21.404  1.00 18.18           O  
ATOM    217  CB  TYR A  40      -7.967   6.503  22.599  1.00 19.00           C  
ATOM    218  CG  TYR A  40      -8.990   5.773  23.383  1.00 18.38           C  
ATOM    219  CD1 TYR A  40      -8.691   5.273  24.630  1.00 18.23           C  
ATOM    220  CD2 TYR A  40     -10.268   5.555  22.868  1.00 16.81           C  
ATOM    221  CE1 TYR A  40      -9.615   4.616  25.396  1.00 17.98           C  
ATOM    222  CE2 TYR A  40     -11.208   4.871  23.592  1.00 16.75           C  
ATOM    223  CZ  TYR A  40     -10.904   4.411  24.859  1.00 17.10           C  
ATOM    224  OH  TYR A  40     -11.876   3.804  25.554  1.00 17.75           O  
ATOM    225  N   TYR A  41      -7.937   5.046  19.909  1.00 16.94           N  
ATOM    226  CA  TYR A  41      -8.716   4.162  19.017  1.00 16.79           C  
ATOM    227  C   TYR A  41      -7.852   3.149  18.288  1.00 18.48           C  
ATOM    228  O   TYR A  41      -8.350   2.073  17.892  1.00 17.44           O  
ATOM    229  CB  TYR A  41      -9.643   4.983  18.077  1.00 14.82           C  
ATOM    230  CG  TYR A  41     -10.883   5.340  18.790  1.00 14.19           C  
ATOM    231  CD1 TYR A  41     -11.899   4.378  18.969  1.00 14.57           C  
ATOM    232  CD2 TYR A  41     -11.115   6.619  19.243  1.00 13.00           C  
ATOM    233  CE1 TYR A  41     -13.054   4.672  19.636  1.00 12.79           C  
ATOM    234  CE2 TYR A  41     -12.259   6.917  19.924  1.00 12.42           C  
ATOM    235  CZ  TYR A  41     -13.224   5.938  20.120  1.00 12.40           C  
ATOM    236  OH  TYR A  41     -14.329   6.237  20.816  1.00 13.06           O  
ATOM    237  N   GLU A  42      -6.542   3.441  18.212  1.00 19.89           N  
ATOM    238  CA  GLU A  42      -5.579   2.524  17.614  1.00 21.80           C  
ATOM    239  C   GLU A  42      -5.456   1.266  18.444  1.00 20.67           C  
ATOM    240  O   GLU A  42      -4.930   0.329  17.933  1.00 22.16           O  
ATOM    241  CB  GLU A  42      -4.197   3.151  17.331  1.00 24.25           C  
ATOM    242  CG  GLU A  42      -4.073   3.672  15.902  1.00 28.36           C  
ATOM    243  CD  GLU A  42      -2.791   4.450  15.603  1.00 33.31           C  
ATOM    244  OE1 GLU A  42      -2.627   4.859  14.435  1.00 38.51           O  
ATOM    245  OE2 GLU A  42      -1.964   4.679  16.511  1.00 36.72           O  
ATOM    246  N   GLN A  43      -6.022   1.179  19.650  1.00 21.30           N  
ATOM    247  CA  GLN A  43      -6.028  -0.100  20.349  1.00 21.96           C  
ATOM    248  C   GLN A  43      -6.930  -1.168  19.694  1.00 23.61           C  
ATOM    249  O   GLN A  43      -6.779  -2.349  20.010  1.00 22.39           O  
ATOM    250  CB  GLN A  43      -6.365   0.043  21.811  1.00 25.49           C  
ATOM    251  CG  GLN A  43      -7.824   0.188  22.184  1.00 26.12           C  
ATOM    252  CD  GLN A  43      -7.977   0.681  23.611  1.00 30.13           C  
ATOM    253  OE1 GLN A  43      -7.894   1.899  23.908  1.00 31.06           O  
ATOM    254  NE2 GLN A  43      -8.231  -0.246  24.503  1.00 26.99           N  
ATOM    255  N   TRP A  44      -7.862  -0.778  18.805  1.00 17.34           N  
ATOM    256  CA  TRP A  44      -8.695  -1.757  18.084  1.00 17.55           C  
ATOM    257  C   TRP A  44      -8.348  -1.937  16.581  1.00 19.50           C  
ATOM    258  O   TRP A  44      -9.054  -2.670  15.878  1.00 23.48           O  
ATOM    259  CB  TRP A  44     -10.165  -1.388  18.272  1.00 16.10           C  
ATOM    260  CG  TRP A  44     -10.576  -1.405  19.670  1.00 16.95           C  
ATOM    261  CD1 TRP A  44     -10.761  -2.510  20.427  1.00 16.82           C  
ATOM    262  CD2 TRP A  44     -10.821  -0.293  20.524  1.00 16.85           C  
ATOM    263  NE1 TRP A  44     -11.089  -2.187  21.696  1.00 18.22           N  
ATOM    264  CE2 TRP A  44     -11.165  -0.820  21.794  1.00 18.26           C  
ATOM    265  CE3 TRP A  44     -10.819   1.095  20.348  1.00 16.45           C  
ATOM    266  CZ2 TRP A  44     -11.498  -0.003  22.888  1.00 16.60           C  
ATOM    267  CZ3 TRP A  44     -11.144   1.894  21.430  1.00 16.34           C  
ATOM    268  CH2 TRP A  44     -11.480   1.352  22.684  1.00 15.73           C  
ATOM    269  N   GLY A  45      -7.306  -1.287  16.099  1.00 18.62           N  
ATOM    270  CA  GLY A  45      -6.892  -1.373  14.711  1.00 20.96           C  
ATOM    271  C   GLY A  45      -6.136  -0.156  14.209  1.00 22.13           C  
ATOM    272  O   GLY A  45      -5.872   0.766  14.927  1.00 26.28           O  
ATOM    273  N   LYS A  46      -5.805  -0.170  12.933  1.00 22.99           N  
ATOM    274  CA  LYS A  46      -5.080   0.892  12.262  1.00 24.80           C  
ATOM    275  C   LYS A  46      -6.141   1.940  11.867  1.00 20.32           C  
ATOM    276  O   LYS A  46      -7.221   1.576  11.380  1.00 16.26           O  
ATOM    277  CB  LYS A  46      -4.444   0.270  11.015  1.00 30.17           C  
ATOM    278  CG  LYS A  46      -3.657   1.193  10.099  1.00 37.51           C  
ATOM    279  CD  LYS A  46      -3.515   0.642   8.672  1.00 45.21           C  
ATOM    280  CE  LYS A  46      -2.685  -0.641   8.629  1.00 50.37           C  
ATOM    281  NZ  LYS A  46      -2.786  -1.284   7.287  1.00 58.06           N  
ATOM    282  N   LEU A  47      -5.857   3.206  12.132  1.00 18.57           N  
ATOM    283  CA  LEU A  47      -6.671   4.327  11.641  1.00 18.22           C  
ATOM    284  C   LEU A  47      -6.101   4.901  10.365  1.00 16.88           C  
ATOM    285  O   LEU A  47      -4.910   5.241  10.317  1.00 17.52           O  
ATOM    286  CB  LEU A  47      -6.747   5.473  12.684  1.00 18.53           C  
ATOM    287  CG  LEU A  47      -7.353   5.170  14.017  1.00 19.06           C  
ATOM    288  CD1 LEU A  47      -7.468   6.443  14.846  1.00 19.61           C  
ATOM    289  CD2 LEU A  47      -8.703   4.507  13.870  1.00 18.35           C  
ATOM    290  N   THR A  48      -6.922   5.001   9.347  1.00 13.13           N  
ATOM    291  CA  THR A  48      -6.495   5.634   8.140  1.00 14.20           C  
ATOM    292  C   THR A  48      -6.748   7.178   8.221  1.00 14.60           C  
ATOM    293  O   THR A  48      -6.333   7.874   7.310  1.00 16.66           O  
ATOM    294  CB  THR A  48      -7.191   5.026   6.935  1.00 14.17           C  
ATOM    295  OG1 THR A  48      -8.605   5.187   7.102  1.00 12.98           O  
ATOM    296  CG2 THR A  48      -6.864   3.540   6.758  1.00 15.04           C  
ATOM    297  N   ASP A  49      -7.534   7.665   9.193  1.00 13.17           N  
ATOM    298  CA  ASP A  49      -7.891   9.093   9.331  1.00 12.83           C  
ATOM    299  C   ASP A  49      -8.366   9.299  10.743  1.00 12.78           C  
ATOM    300  O   ASP A  49      -9.035   8.412  11.384  1.00 10.88           O  
ATOM    301  CB  ASP A  49      -8.928   9.553   8.282  1.00 13.42           C  
ATOM    302  CG  ASP A  49      -9.261  11.082   8.348  1.00 16.46           C  
ATOM    303  OD1 ASP A  49      -8.306  11.862   8.364  1.00 14.18           O  
ATOM    304  OD2 ASP A  49     -10.452  11.528   8.353  1.00 16.49           O  
ATOM    305  N   CYS A  50      -7.994  10.432  11.289  1.00 12.82           N  
ATOM    306  CA  CYS A  50      -8.326  10.790  12.623  1.00 16.00           C  
ATOM    307  C   CYS A  50      -8.443  12.340  12.607  1.00 19.34           C  
ATOM    308  O   CYS A  50      -7.501  12.989  12.085  1.00 22.02           O  
ATOM    309  CB  CYS A  50      -7.177  10.376  13.512  1.00 18.29           C  
ATOM    310  SG  CYS A  50      -7.543  10.676  15.227  1.00 21.58           S  
ATOM    311  N   VAL A  51      -9.549  12.918  13.075  1.00 15.62           N  
ATOM    312  CA  VAL A  51      -9.712  14.366  13.090  1.00 14.52           C  
ATOM    313  C   VAL A  51     -10.468  14.833  14.313  1.00 14.20           C  
ATOM    314  O   VAL A  51     -11.417  14.212  14.740  1.00 11.93           O  
ATOM    315  CB  VAL A  51     -10.305  14.897  11.786  1.00 15.85           C  
ATOM    316  CG1 VAL A  51     -11.731  14.380  11.515  1.00 15.90           C  
ATOM    317  CG2 VAL A  51     -10.339  16.435  11.752  1.00 17.65           C  
ATOM    318  N   VAL A  52     -10.018  15.949  14.896  1.00 13.28           N  
ATOM    319  CA  VAL A  52     -10.766  16.644  15.959  1.00 13.28           C  
ATOM    320  C   VAL A  52     -11.203  17.957  15.302  1.00 13.62           C  
ATOM    321  O   VAL A  52     -10.349  18.688  14.808  1.00 14.60           O  
ATOM    322  CB  VAL A  52      -9.926  16.985  17.175  1.00 13.42           C  
ATOM    323  CG1 VAL A  52     -10.654  17.895  18.161  1.00 13.20           C  
ATOM    324  CG2 VAL A  52      -9.441  15.753  17.926  1.00 15.56           C  
ATOM    325  N   MET A  53     -12.480  18.235  15.299  1.00 12.76           N  
ATOM    326  CA  MET A  53     -12.980  19.429  14.699  1.00 13.25           C  
ATOM    327  C   MET A  53     -12.706  20.653  15.595  1.00 14.36           C  
ATOM    328  O   MET A  53     -12.948  20.634  16.748  1.00 12.65           O  
ATOM    329  CB  MET A  53     -14.449  19.336  14.418  1.00 13.38           C  
ATOM    330  CG  MET A  53     -14.789  18.871  13.031  1.00 13.06           C  
ATOM    331  SD  MET A  53     -14.126  17.278  12.654  1.00 13.38           S  
ATOM    332  CE  MET A  53     -14.348  17.289  10.895  1.00 12.85           C  
ATOM    333  N   ARG A  54     -12.224  21.701  14.980  1.00 16.27           N  
ATOM    334  CA AARG A  54     -11.742  22.899  15.679  0.50 16.74           C  
ATOM    335  CA BARG A  54     -11.837  22.920  15.694  0.50 17.34           C  
ATOM    336  C   ARG A  54     -12.372  24.154  15.020  1.00 19.39           C  
ATOM    337  O   ARG A  54     -12.748  24.130  13.845  1.00 17.20           O  
ATOM    338  CB AARG A  54     -10.190  22.965  15.675  0.50 16.49           C  
ATOM    339  CB BARG A  54     -10.348  23.071  15.754  0.50 18.14           C  
ATOM    340  CG AARG A  54      -9.419  21.957  16.552  0.50 15.68           C  
ATOM    341  CG BARG A  54      -9.707  21.994  16.539  0.50 18.45           C  
ATOM    342  CD AARG A  54      -7.911  21.880  16.235  0.50 14.80           C  
ATOM    343  CD BARG A  54      -8.254  22.277  16.773  0.50 18.39           C  
ATOM    344  NE AARG A  54      -7.130  20.878  17.019  0.50 14.26           N  
ATOM    345  NE BARG A  54      -7.760  21.121  17.455  0.50 19.06           N  
ATOM    346  CZ AARG A  54      -6.996  19.589  16.665  0.50 13.43           C  
ATOM    347  CZ BARG A  54      -7.777  20.960  18.758  0.50 19.23           C  
ATOM    348  NH1AARG A  54      -7.596  19.216  15.529  0.50 10.76           N  
ATOM    349  NH1BARG A  54      -8.188  21.959  19.551  0.50 15.61           N  
ATOM    350  NH2AARG A  54      -6.244  18.696  17.426  0.50 13.05           N  
ATOM    351  NH2BARG A  54      -7.339  19.797  19.236  0.50 19.85           N  
ATOM    352  N   ASP A  55     -12.561  25.218  15.815  1.00 20.12           N  
ATOM    353  CA  ASP A  55     -12.990  26.502  15.275  1.00 21.91           C  
ATOM    354  C   ASP A  55     -11.873  26.994  14.371  1.00 20.27           C  
ATOM    355  O   ASP A  55     -10.699  26.953  14.742  1.00 21.03           O  
ATOM    356  CB  ASP A  55     -13.248  27.533  16.384  1.00 25.45           C  
ATOM    357  CG  ASP A  55     -13.594  28.912  15.806  1.00 29.20           C  
ATOM    358  OD1 ASP A  55     -14.759  29.120  15.472  1.00 32.98           O  
ATOM    359  OD2 ASP A  55     -12.695  29.739  15.612  1.00 32.57           O  
ATOM    360  N   PRO A  56     -12.212  27.446  13.149  1.00 24.57           N  
ATOM    361  CA  PRO A  56     -11.111  27.853  12.266  1.00 28.07           C  
ATOM    362  C   PRO A  56     -10.249  29.047  12.742  1.00 31.44           C  
ATOM    363  O   PRO A  56      -9.058  29.103  12.425  1.00 35.80           O  
ATOM    364  CB  PRO A  56     -11.791  28.185  10.934  1.00 28.92           C  
ATOM    365  CG  PRO A  56     -13.248  28.269  11.213  1.00 27.96           C  
ATOM    366  CD  PRO A  56     -13.542  27.714  12.575  1.00 28.08           C  
ATOM    367  N   ALA A  57     -10.783  29.953  13.527  1.00 27.56           N  
ATOM    368  CA  ALA A  57      -9.933  31.098  13.935  1.00 29.00           C  
ATOM    369  C   ALA A  57      -9.317  30.846  15.294  1.00 27.01           C  
ATOM    370  O   ALA A  57      -8.130  31.045  15.448  1.00 25.47           O  
ATOM    371  CB  ALA A  57     -10.737  32.393  13.937  1.00 29.89           C  
ATOM    372  N   SER A  58     -10.112  30.416  16.281  1.00 22.76           N  
ATOM    373  CA  SER A  58      -9.589  30.240  17.608  1.00 25.97           C  
ATOM    374  C   SER A  58      -8.852  28.931  17.756  1.00 25.89           C  
ATOM    375  O   SER A  58      -8.093  28.801  18.689  1.00 25.63           O  
ATOM    376  CB  SER A  58     -10.663  30.305  18.671  1.00 28.31           C  
ATOM    377  OG  SER A  58     -11.579  29.209  18.608  1.00 29.26           O  
ATOM    378  N   LYS A  59      -9.119  27.943  16.888  1.00 27.63           N  
ATOM    379  CA  LYS A  59      -8.583  26.589  17.077  1.00 30.42           C  
ATOM    380  C   LYS A  59      -9.011  25.899  18.382  1.00 28.91           C  
ATOM    381  O   LYS A  59      -8.429  24.890  18.769  1.00 29.99           O  
ATOM    382  CB  LYS A  59      -7.084  26.579  16.902  1.00 32.65           C  
ATOM    383  CG  LYS A  59      -6.710  26.777  15.442  1.00 38.80           C  
ATOM    384  CD  LYS A  59      -5.607  27.784  15.150  1.00 46.45           C  
ATOM    385  CE  LYS A  59      -4.732  28.240  16.311  1.00 51.61           C  
ATOM    386  NZ  LYS A  59      -3.972  27.207  17.078  1.00 59.75           N  
ATOM    387  N   ARG A  60     -10.090  26.402  18.961  1.00 28.42           N  
ATOM    388  CA  ARG A  60     -10.775  25.801  20.067  1.00 29.97           C  
ATOM    389  C   ARG A  60     -11.513  24.550  19.551  1.00 27.73           C  
ATOM    390  O   ARG A  60     -12.247  24.634  18.546  1.00 24.40           O  
ATOM    391  CB  ARG A  60     -11.819  26.774  20.567  1.00 35.68           C  
ATOM    392  CG  ARG A  60     -12.562  26.397  21.833  1.00 47.25           C  
ATOM    393  CD  ARG A  60     -13.878  27.170  21.945  1.00 59.44           C  
ATOM    394  NE  ARG A  60     -14.533  26.909  23.230  1.00 69.93           N  
ATOM    395  CZ  ARG A  60     -15.644  26.187  23.424  1.00 72.58           C  
ATOM    396  NH1 ARG A  60     -16.315  25.621  22.412  1.00 74.88           N  
ATOM    397  NH2 ARG A  60     -16.100  26.031  24.666  1.00 70.09           N  
ATOM    398  N   SER A  61     -11.414  23.446  20.303  1.00 22.68           N  
ATOM    399  CA  SER A  61     -12.098  22.216  19.902  1.00 21.25           C  
ATOM    400  C   SER A  61     -13.598  22.445  19.915  1.00 19.51           C  
ATOM    401  O   SER A  61     -14.139  23.096  20.801  1.00 19.79           O  
ATOM    402  CB  SER A  61     -11.716  21.041  20.847  1.00 21.04           C  
ATOM    403  OG  SER A  61     -12.619  19.941  20.674  1.00 18.86           O  
ATOM    404  N   ARG A  62     -14.278  21.910  18.913  1.00 17.58           N  
ATOM    405  CA  ARG A  62     -15.704  21.842  18.889  1.00 19.70           C  
ATOM    406  C   ARG A  62     -16.271  20.661  19.679  1.00 18.57           C  
ATOM    407  O   ARG A  62     -17.511  20.484  19.755  1.00 19.79           O  
ATOM    408  CB  ARG A  62     -16.192  21.800  17.437  1.00 22.04           C  
ATOM    409  CG  ARG A  62     -15.774  23.061  16.687  1.00 23.01           C  
ATOM    410  CD  ARG A  62     -16.045  23.011  15.194  1.00 25.44           C  
ATOM    411  NE  ARG A  62     -17.405  22.650  14.844  1.00 24.60           N  
ATOM    412  CZ  ARG A  62     -17.764  22.268  13.605  1.00 26.50           C  
ATOM    413  NH1 ARG A  62     -16.875  22.140  12.605  1.00 28.44           N  
ATOM    414  NH2 ARG A  62     -19.000  21.987  13.376  1.00 24.67           N  
ATOM    415  N   GLY A  63     -15.407  19.848  20.278  1.00 17.78           N  
ATOM    416  CA  GLY A  63     -15.916  18.768  21.139  1.00 17.67           C  
ATOM    417  C   GLY A  63     -16.363  17.479  20.466  1.00 15.89           C  
ATOM    418  O   GLY A  63     -17.072  16.685  21.064  1.00 17.81           O  
ATOM    419  N   PHE A  64     -16.035  17.319  19.194  1.00 14.56           N  
ATOM    420  CA  PHE A  64     -16.254  16.076  18.473  1.00 14.70           C  
ATOM    421  C   PHE A  64     -15.158  15.874  17.426  1.00 13.44           C  
ATOM    422  O   PHE A  64     -14.390  16.797  17.068  1.00 12.73           O  
ATOM    423  CB  PHE A  64     -17.613  16.017  17.787  1.00 14.65           C  
ATOM    424  CG  PHE A  64     -17.767  16.973  16.634  1.00 16.46           C  
ATOM    425  CD1 PHE A  64     -18.073  18.332  16.875  1.00 15.69           C  
ATOM    426  CD2 PHE A  64     -17.618  16.538  15.310  1.00 16.01           C  
ATOM    427  CE1 PHE A  64     -18.227  19.220  15.814  1.00 18.41           C  
ATOM    428  CE2 PHE A  64     -17.776  17.419  14.254  1.00 16.96           C  
ATOM    429  CZ  PHE A  64     -18.068  18.768  14.503  1.00 19.78           C  
ATOM    430  N   GLY A  65     -15.096  14.658  16.945  1.00 11.17           N  
ATOM    431  CA  GLY A  65     -14.226  14.339  15.824  1.00 10.50           C  
ATOM    432  C   GLY A  65     -14.652  13.043  15.157  1.00 10.15           C  
ATOM    433  O   GLY A  65     -15.776  12.585  15.381  1.00  9.58           O  
ATOM    434  N   PHE A  66     -13.775  12.526  14.298  1.00  9.06           N  
ATOM    435  CA  PHE A  66     -14.035  11.262  13.548  1.00  9.34           C  
ATOM    436  C   PHE A  66     -12.781  10.425  13.529  1.00 10.68           C  
ATOM    437  O   PHE A  66     -11.635  10.944  13.429  1.00  9.89           O  
ATOM    438  CB  PHE A  66     -14.442  11.471  12.124  1.00  9.54           C  
ATOM    439  CG  PHE A  66     -15.743  12.194  11.940  1.00  9.38           C  
ATOM    440  CD1 PHE A  66     -15.773  13.573  11.964  1.00  9.74           C  
ATOM    441  CD2 PHE A  66     -16.951  11.513  11.773  1.00 10.36           C  
ATOM    442  CE1 PHE A  66     -16.968  14.263  11.800  1.00 10.07           C  
ATOM    443  CE2 PHE A  66     -18.185  12.212  11.612  1.00 10.33           C  
ATOM    444  CZ  PHE A  66     -18.182  13.590  11.541  1.00  9.94           C  
ATOM    445  N   VAL A  67     -12.983   9.125  13.626  1.00 10.45           N  
ATOM    446  CA  VAL A  67     -11.888   8.217  13.378  1.00 11.06           C  
ATOM    447  C   VAL A  67     -12.325   7.244  12.290  1.00 11.33           C  
ATOM    448  O   VAL A  67     -13.519   6.849  12.248  1.00 10.52           O  
ATOM    449  CB  VAL A  67     -11.420   7.452  14.627  1.00 11.40           C  
ATOM    450  CG1 VAL A  67     -10.859   8.410  15.663  1.00 12.25           C  
ATOM    451  CG2 VAL A  67     -12.535   6.700  15.294  1.00 13.11           C  
ATOM    452  N   THR A  68     -11.395   6.843  11.453  1.00 10.15           N  
ATOM    453  CA  THR A  68     -11.695   5.960  10.369  1.00 11.25           C  
ATOM    454  C   THR A  68     -10.710   4.760  10.473  1.00 11.87           C  
ATOM    455  O   THR A  68      -9.526   4.943  10.426  1.00 11.58           O  
ATOM    456  CB  THR A  68     -11.576   6.631   9.019  1.00 11.99           C  
ATOM    457  OG1 THR A  68     -12.439   7.795   8.962  1.00 13.21           O  
ATOM    458  CG2 THR A  68     -11.929   5.655   7.885  1.00 12.49           C  
ATOM    459  N   PHE A  69     -11.227   3.570  10.637  1.00 12.26           N  
ATOM    460  CA  PHE A  69     -10.426   2.371  10.746  1.00 13.58           C  
ATOM    461  C   PHE A  69     -10.084   1.798   9.377  1.00 15.55           C  
ATOM    462  O   PHE A  69     -10.688   2.196   8.360  1.00 14.30           O  
ATOM    463  CB  PHE A  69     -11.174   1.347  11.577  1.00 13.71           C  
ATOM    464  CG  PHE A  69     -11.115   1.611  13.036  1.00 13.85           C  
ATOM    465  CD1 PHE A  69     -10.001   1.168  13.765  1.00 15.15           C  
ATOM    466  CD2 PHE A  69     -12.134   2.264  13.698  1.00 13.30           C  
ATOM    467  CE1 PHE A  69      -9.916   1.402  15.139  1.00 15.78           C  
ATOM    468  CE2 PHE A  69     -12.040   2.508  15.067  1.00 13.73           C  
ATOM    469  CZ  PHE A  69     -10.945   2.069  15.779  1.00 13.78           C  
ATOM    470  N   SER A  70      -9.155   0.829   9.343  1.00 16.72           N  
ATOM    471  CA  SER A  70      -8.841   0.224   8.045  1.00 19.11           C  
ATOM    472  C   SER A  70      -9.896  -0.828   7.598  1.00 19.77           C  
ATOM    473  O   SER A  70      -9.946  -1.125   6.437  1.00 22.07           O  
ATOM    474  CB  SER A  70      -7.425  -0.365   7.998  1.00 23.77           C  
ATOM    475  OG  SER A  70      -7.346  -1.442   8.875  1.00 27.89           O  
ATOM    476  N   SER A  71     -10.741  -1.322   8.487  1.00 18.63           N  
ATOM    477  CA  SER A  71     -11.790  -2.258   8.161  1.00 19.16           C  
ATOM    478  C   SER A  71     -12.999  -2.100   9.049  1.00 16.91           C  
ATOM    479  O   SER A  71     -12.892  -1.649  10.173  1.00 14.47           O  
ATOM    480  CB  SER A  71     -11.287  -3.691   8.321  1.00 21.27           C  
ATOM    481  OG  SER A  71     -11.101  -3.933   9.707  1.00 20.57           O  
ATOM    482  N   MET A  72     -14.151  -2.569   8.575  1.00 15.61           N  
ATOM    483  CA  MET A  72     -15.359  -2.547   9.377  1.00 15.90           C  
ATOM    484  C   MET A  72     -15.260  -3.487  10.573  1.00 15.04           C  
ATOM    485  O   MET A  72     -15.799  -3.201  11.591  1.00 13.07           O  
ATOM    486  CB  MET A  72     -16.601  -2.874   8.538  1.00 19.59           C  
ATOM    487  CG  MET A  72     -17.946  -2.712   9.269  1.00 24.17           C  
ATOM    488  SD  MET A  72     -19.454  -3.165   8.270  1.00 32.29           S  
ATOM    489  CE  MET A  72     -18.791  -3.363   6.622  1.00 30.53           C  
ATOM    490  N   ALA A  73     -14.554  -4.596  10.451  1.00 16.67           N  
ATOM    491  CA  ALA A  73     -14.298  -5.466  11.610  1.00 17.52           C  
ATOM    492  C   ALA A  73     -13.598  -4.721  12.799  1.00 17.37           C  
ATOM    493  O   ALA A  73     -13.870  -5.010  13.958  1.00 15.67           O  
ATOM    494  CB  ALA A  73     -13.413  -6.641  11.181  1.00 19.16           C  
ATOM    495  N   GLU A  74     -12.669  -3.812  12.484  1.00 17.02           N  
ATOM    496  CA  GLU A  74     -12.054  -2.973  13.506  1.00 17.03           C  
ATOM    497  C   GLU A  74     -13.043  -2.063  14.183  1.00 15.09           C  
ATOM    498  O   GLU A  74     -13.040  -1.934  15.433  1.00 14.58           O  
ATOM    499  CB  GLU A  74     -10.879  -2.220  12.926  1.00 17.59           C  
ATOM    500  CG  GLU A  74      -9.712  -3.118  12.562  1.00 19.55           C  
ATOM    501  CD  GLU A  74      -8.642  -2.451  11.728  1.00 23.79           C  
ATOM    502  OE1 GLU A  74      -8.801  -1.324  11.171  1.00 24.99           O  
ATOM    503  OE2 GLU A  74      -7.555  -3.036  11.677  1.00 25.60           O  
ATOM    504  N   VAL A  75     -13.898  -1.403  13.391  1.00 14.00           N  
ATOM    505  CA  VAL A  75     -14.968  -0.648  13.957  1.00 13.60           C  
ATOM    506  C   VAL A  75     -15.834  -1.473  14.919  1.00 14.43           C  
ATOM    507  O   VAL A  75     -16.139  -1.061  16.011  1.00 12.07           O  
ATOM    508  CB  VAL A  75     -15.901  -0.021  12.892  1.00 13.41           C  
ATOM    509  CG1 VAL A  75     -16.933   0.794  13.602  1.00 13.95           C  
ATOM    510  CG2 VAL A  75     -15.112   0.848  11.925  1.00 14.63           C  
ATOM    511  N   ASP A  76     -16.218  -2.674  14.480  1.00 14.83           N  
ATOM    512  CA  ASP A  76     -17.075  -3.497  15.341  1.00 17.07           C  
ATOM    513  C   ASP A  76     -16.388  -3.858  16.643  1.00 14.58           C  
ATOM    514  O   ASP A  76     -17.019  -3.826  17.659  1.00 14.70           O  
ATOM    515  CB  ASP A  76     -17.480  -4.797  14.621  1.00 17.17           C  
ATOM    516  CG  ASP A  76     -18.389  -4.551  13.429  1.00 21.10           C  
ATOM    517  OD1 ASP A  76     -19.143  -3.553  13.366  1.00 20.59           O  
ATOM    518  OD2 ASP A  76     -18.345  -5.407  12.540  1.00 22.63           O  
ATOM    519  N   ALA A  77     -15.099  -4.164  16.552  1.00 16.15           N  
ATOM    520  CA  ALA A  77     -14.243  -4.474  17.738  1.00 16.66           C  
ATOM    521  C   ALA A  77     -14.206  -3.274  18.729  1.00 16.66           C  
ATOM    522  O   ALA A  77     -14.410  -3.426  19.925  1.00 14.43           O  
ATOM    523  CB  ALA A  77     -12.849  -4.850  17.274  1.00 16.25           C  
ATOM    524  N   ALA A  78     -14.048  -2.059  18.218  1.00 15.25           N  
ATOM    525  CA  ALA A  78     -14.129  -0.902  19.096  1.00 12.97           C  
ATOM    526  C   ALA A  78     -15.513  -0.717  19.717  1.00 14.27           C  
ATOM    527  O   ALA A  78     -15.673  -0.546  20.934  1.00 13.18           O  
ATOM    528  CB  ALA A  78     -13.702   0.327  18.310  1.00 13.49           C  
ATOM    529  N   MET A  79     -16.581  -0.810  18.897  1.00 13.46           N  
ATOM    530  CA  MET A  79     -17.896  -0.664  19.453  1.00 13.77           C  
ATOM    531  C   MET A  79     -18.328  -1.780  20.444  1.00 16.64           C  
ATOM    532  O   MET A  79     -19.171  -1.530  21.302  1.00 18.23           O  
ATOM    533  CB  MET A  79     -18.922  -0.557  18.295  1.00 14.35           C  
ATOM    534  CG  MET A  79     -18.743   0.731  17.491  1.00 13.67           C  
ATOM    535  SD  MET A  79     -18.815   2.292  18.426  1.00 13.89           S  
ATOM    536  CE  MET A  79     -20.561   2.527  18.534  1.00 14.19           C  
ATOM    537  N   ALA A  80     -17.770  -2.978  20.301  1.00 18.03           N  
ATOM    538  CA  ALA A  80     -17.990  -4.068  21.283  1.00 20.98           C  
ATOM    539  C   ALA A  80     -17.302  -3.787  22.616  1.00 22.37           C  
ATOM    540  O   ALA A  80     -17.565  -4.464  23.585  1.00 26.99           O  
ATOM    541  CB  ALA A  80     -17.438  -5.366  20.726  1.00 20.71           C  
ATOM    542  N   ALA A  81     -16.379  -2.837  22.651  1.00 23.58           N  
ATOM    543  CA  ALA A  81     -15.644  -2.457  23.848  1.00 22.70           C  
ATOM    544  C   ALA A  81     -16.063  -1.128  24.450  1.00 23.18           C  
ATOM    545  O   ALA A  81     -15.290  -0.520  25.198  1.00 23.18           O  
ATOM    546  CB  ALA A  81     -14.135  -2.469  23.502  1.00 23.80           C  
ATOM    547  N   ARG A  82     -17.283  -0.655  24.160  1.00 20.09           N  
ATOM    548  CA  ARG A  82     -17.831   0.499  24.862  1.00 18.66           C  
ATOM    549  C   ARG A  82     -18.036   0.140  26.352  1.00 21.82           C  
ATOM    550  O   ARG A  82     -18.196  -1.023  26.615  1.00 22.24           O  
ATOM    551  CB  ARG A  82     -19.152   0.937  24.229  1.00 17.96           C  
ATOM    552  CG  ARG A  82     -18.904   1.655  22.917  1.00 18.24           C  
ATOM    553  CD  ARG A  82     -20.184   1.979  22.180  1.00 15.72           C  
ATOM    554  NE  ARG A  82     -20.753   0.678  21.784  1.00 15.79           N  
ATOM    555  CZ  ARG A  82     -22.046   0.442  21.594  1.00 16.27           C  
ATOM    556  NH1 ARG A  82     -22.944   1.386  21.701  1.00 16.61           N  
ATOM    557  NH2 ARG A  82     -22.435  -0.765  21.252  1.00 17.51           N  
ATOM    558  N   PRO A  83     -18.039   1.088  27.296  1.00 21.82           N  
ATOM    559  CA  PRO A  83     -17.870   2.518  27.029  1.00 20.98           C  
ATOM    560  C   PRO A  83     -16.439   2.938  26.786  1.00 19.86           C  
ATOM    561  O   PRO A  83     -15.452   2.244  27.129  1.00 18.90           O  
ATOM    562  CB  PRO A  83     -18.581   3.228  28.242  1.00 24.26           C  
ATOM    563  CG  PRO A  83     -18.606   2.180  29.361  1.00 25.21           C  
ATOM    564  CD  PRO A  83     -18.483   0.803  28.685  1.00 26.19           C  
ATOM    565  N   HIS A  84     -16.295   4.070  26.083  1.00 18.20           N  
ATOM    566  CA  HIS A  84     -15.021   4.611  25.716  1.00 14.73           C  
ATOM    567  C   HIS A  84     -14.831   5.874  26.545  1.00 15.57           C  
ATOM    568  O   HIS A  84     -15.789   6.661  26.748  1.00 16.01           O  
ATOM    569  CB  HIS A  84     -14.962   4.969  24.216  1.00 14.14           C  
ATOM    570  CG  HIS A  84     -15.080   3.791  23.308  1.00 13.58           C  
ATOM    571  ND1 HIS A  84     -15.440   3.903  21.985  1.00 12.75           N  
ATOM    572  CD2 HIS A  84     -14.835   2.479  23.524  1.00 13.01           C  
ATOM    573  CE1 HIS A  84     -15.442   2.710  21.431  1.00 13.64           C  
ATOM    574  NE2 HIS A  84     -15.046   1.827  22.335  1.00 13.97           N  
ATOM    575  N   SER A  85     -13.618   6.084  27.025  1.00 18.76           N  
ATOM    576  CA  SER A  85     -13.303   7.349  27.699  1.00 19.70           C  
ATOM    577  C   SER A  85     -11.928   7.804  27.297  1.00 18.74           C  
ATOM    578  O   SER A  85     -10.987   7.010  27.074  1.00 20.43           O  
ATOM    579  CB  SER A  85     -13.489   7.207  29.210  1.00 21.62           C  
ATOM    580  OG  SER A  85     -12.574   6.250  29.700  1.00 24.80           O  
ATOM    581  N   ILE A  86     -11.803   9.100  27.110  1.00 17.78           N  
ATOM    582  CA  ILE A  86     -10.527   9.694  26.642  1.00 17.49           C  
ATOM    583  C   ILE A  86     -10.394  11.008  27.399  1.00 16.71           C  
ATOM    584  O   ILE A  86     -11.375  11.792  27.524  1.00 13.78           O  
ATOM    585  CB  ILE A  86     -10.578  10.022  25.120  1.00 19.64           C  
ATOM    586  CG1 ILE A  86     -10.863   8.780  24.301  1.00 22.83           C  
ATOM    587  CG2 ILE A  86      -9.278  10.638  24.638  1.00 21.47           C  
ATOM    588  CD1 ILE A  86     -11.003   9.060  22.810  1.00 25.92           C  
ATOM    589  N   ASP A  87      -9.187  11.277  27.900  1.00 18.84           N  
ATOM    590  CA  ASP A  87      -8.914  12.480  28.670  1.00 18.62           C  
ATOM    591  C   ASP A  87      -9.922  12.772  29.728  1.00 17.66           C  
ATOM    592  O   ASP A  87     -10.335  13.933  29.918  1.00 20.17           O  
ATOM    593  CB  ASP A  87      -8.691  13.664  27.709  1.00 20.81           C  
ATOM    594  CG  ASP A  87      -7.532  13.414  26.745  1.00 23.61           C  
ATOM    595  OD1 ASP A  87      -6.522  12.801  27.163  1.00 27.94           O  
ATOM    596  OD2 ASP A  87      -7.625  13.715  25.531  1.00 27.84           O  
ATOM    597  N   GLY A  88     -10.342  11.717  30.431  1.00 18.62           N  
ATOM    598  CA  GLY A  88     -11.292  11.831  31.520  1.00 18.83           C  
ATOM    599  C   GLY A  88     -12.772  12.063  31.207  1.00 20.24           C  
ATOM    600  O   GLY A  88     -13.595  12.224  32.121  1.00 17.48           O  
ATOM    601  N   ARG A  89     -13.154  12.005  29.923  1.00 20.63           N  
ATOM    602  CA  ARG A  89     -14.574  12.105  29.559  1.00 21.73           C  
ATOM    603  C   ARG A  89     -15.043  10.818  28.927  1.00 18.60           C  
ATOM    604  O   ARG A  89     -14.308  10.241  28.203  1.00 18.79           O  
ATOM    605  CB  ARG A  89     -14.792  13.190  28.515  1.00 26.70           C  
ATOM    606  CG  ARG A  89     -14.310  14.542  28.920  1.00 32.94           C  
ATOM    607  CD  ARG A  89     -15.290  15.264  29.812  1.00 37.98           C  
ATOM    608  NE  ARG A  89     -14.800  16.631  29.939  1.00 50.97           N  
ATOM    609  CZ  ARG A  89     -13.723  17.006  30.653  1.00 56.09           C  
ATOM    610  NH1 ARG A  89     -13.367  18.292  30.638  1.00 58.89           N  
ATOM    611  NH2 ARG A  89     -13.010  16.138  31.406  1.00 53.32           N  
ATOM    612  N   VAL A  90     -16.275  10.429  29.200  1.00 16.55           N  
ATOM    613  CA  VAL A  90     -16.922   9.310  28.572  1.00 18.24           C  
ATOM    614  C   VAL A  90     -17.400   9.889  27.212  1.00 16.12           C  
ATOM    615  O   VAL A  90     -18.186  10.835  27.178  1.00 15.98           O  
ATOM    616  CB  VAL A  90     -18.130   8.775  29.366  1.00 19.87           C  
ATOM    617  CG1 VAL A  90     -18.759   7.596  28.648  1.00 22.07           C  
ATOM    618  CG2 VAL A  90     -17.733   8.402  30.819  1.00 18.83           C  
ATOM    619  N   VAL A  91     -16.817   9.374  26.148  1.00 14.94           N  
ATOM    620  CA  VAL A  91     -17.077   9.868  24.794  1.00 16.33           C  
ATOM    621  C   VAL A  91     -18.283   9.082  24.223  1.00 17.09           C  
ATOM    622  O   VAL A  91     -18.724   8.092  24.824  1.00 14.09           O  
ATOM    623  CB  VAL A  91     -15.826   9.854  23.922  1.00 17.14           C  
ATOM    624  CG1 VAL A  91     -14.763  10.762  24.559  1.00 18.03           C  
ATOM    625  CG2 VAL A  91     -15.268   8.457  23.640  1.00 17.69           C  
ATOM    626  N   GLU A  92     -18.848   9.574  23.125  1.00 16.39           N  
ATOM    627  CA  GLU A  92     -20.067   9.005  22.553  1.00 17.86           C  
ATOM    628  C   GLU A  92     -19.822   8.643  21.075  1.00 14.92           C  
ATOM    629  O   GLU A  92     -20.078   9.447  20.175  1.00 13.43           O  
ATOM    630  CB  GLU A  92     -21.227   9.954  22.776  1.00 23.19           C  
ATOM    631  CG  GLU A  92     -21.590   9.997  24.262  1.00 30.76           C  
ATOM    632  CD  GLU A  92     -22.846  10.793  24.615  1.00 37.69           C  
ATOM    633  OE1 GLU A  92     -22.733  11.603  25.566  1.00 41.72           O  
ATOM    634  OE2 GLU A  92     -23.936  10.610  23.997  1.00 46.52           O  
ATOM    635  N   PRO A  93     -19.286   7.446  20.849  1.00 13.90           N  
ATOM    636  CA  PRO A  93     -19.015   6.986  19.512  1.00 13.54           C  
ATOM    637  C   PRO A  93     -20.317   6.554  18.833  1.00 14.50           C  
ATOM    638  O   PRO A  93     -21.202   5.950  19.479  1.00 12.65           O  
ATOM    639  CB  PRO A  93     -18.108   5.791  19.698  1.00 12.90           C  
ATOM    640  CG  PRO A  93     -18.460   5.267  21.084  1.00 13.47           C  
ATOM    641  CD  PRO A  93     -18.932   6.427  21.882  1.00 14.39           C  
ATOM    642  N   LYS A  94     -20.385   6.792  17.539  1.00 13.28           N  
ATOM    643  CA  LYS A  94     -21.518   6.392  16.767  1.00 14.08           C  
ATOM    644  C   LYS A  94     -21.073   6.181  15.334  1.00 11.86           C  
ATOM    645  O   LYS A  94     -20.228   6.889  14.853  1.00 12.22           O  
ATOM    646  CB  LYS A  94     -22.619   7.462  16.750  1.00 17.37           C  
ATOM    647  CG  LYS A  94     -23.104   7.879  18.076  1.00 24.80           C  
ATOM    648  CD  LYS A  94     -24.507   8.382  18.080  1.00 34.39           C  
ATOM    649  CE  LYS A  94     -25.242   7.909  19.332  1.00 39.21           C  
ATOM    650  NZ  LYS A  94     -24.658   8.416  20.611  1.00 38.47           N  
ATOM    651  N   ARG A  95     -21.673   5.220  14.668  1.00 10.37           N  
ATOM    652  CA  ARG A  95     -21.357   5.032  13.254  1.00 11.23           C  
ATOM    653  C   ARG A  95     -21.648   6.326  12.572  1.00 10.57           C  
ATOM    654  O   ARG A  95     -22.686   6.952  12.788  1.00  9.81           O  
ATOM    655  CB  ARG A  95     -22.192   3.923  12.583  1.00 13.00           C  
ATOM    656  CG  ARG A  95     -22.354   2.637  13.373  1.00 15.04           C  
ATOM    657  CD  ARG A  95     -21.253   1.680  13.133  1.00 14.69           C  
ATOM    658  NE  ARG A  95     -21.291   0.549  14.038  1.00 14.56           N  
ATOM    659  CZ  ARG A  95     -20.660  -0.602  13.842  1.00 14.29           C  
ATOM    660  NH1 ARG A  95     -19.934  -0.879  12.753  1.00 16.09           N  
ATOM    661  NH2 ARG A  95     -20.661  -1.494  14.824  1.00 16.85           N  
ATOM    662  N   ALA A  96     -20.718   6.753  11.742  1.00 10.14           N  
ATOM    663  CA  ALA A  96     -20.857   7.994  11.029  1.00 10.31           C  
ATOM    664  C   ALA A  96     -22.009   8.005  10.033  1.00 11.11           C  
ATOM    665  O   ALA A  96     -22.182   7.039   9.294  1.00 12.17           O  
ATOM    666  CB  ALA A  96     -19.525   8.393  10.365  1.00 11.09           C  
ATOM    667  N   VAL A  97     -22.837   9.028  10.140  1.00 10.93           N  
ATOM    668  CA  VAL A  97     -23.935   9.273   9.181  1.00 13.51           C  
ATOM    669  C   VAL A  97     -23.400  10.151   8.012  1.00 13.69           C  
ATOM    670  O   VAL A  97     -22.950  11.241   8.230  1.00 12.85           O  
ATOM    671  CB  VAL A  97     -25.128   9.857   9.873  1.00 15.36           C  
ATOM    672  CG1 VAL A  97     -26.313  10.002   8.878  1.00 17.48           C  
ATOM    673  CG2 VAL A  97     -25.565   8.917  11.016  1.00 17.64           C  
ATOM    674  N   ALA A  98     -23.526   9.656   6.799  1.00 12.89           N  
ATOM    675  CA  ALA A  98     -23.032  10.331   5.612  1.00 14.32           C  
ATOM    676  C   ALA A  98     -23.619  11.731   5.516  1.00 12.63           C  
ATOM    677  O   ALA A  98     -24.774  11.988   5.911  1.00 13.05           O  
ATOM    678  CB  ALA A  98     -23.322   9.497   4.369  1.00 15.07           C  
ATOM    679  N   ARG A  99     -22.797  12.663   5.122  1.00 12.99           N  
ATOM    680  CA  ARG A  99     -23.189  14.080   5.013  1.00 14.48           C  
ATOM    681  C   ARG A  99     -24.482  14.272   4.133  1.00 15.30           C  
ATOM    682  O   ARG A  99     -25.332  15.064   4.519  1.00 16.37           O  
ATOM    683  CB  ARG A  99     -22.003  14.814   4.440  1.00 15.48           C  
ATOM    684  CG  ARG A  99     -22.153  16.272   4.280  1.00 17.40           C  
ATOM    685  CD  ARG A  99     -20.786  16.957   4.208  1.00 15.87           C  
ATOM    686  NE  ARG A  99     -20.074  16.626   2.991  1.00 14.65           N  
ATOM    687  CZ  ARG A  99     -18.954  17.240   2.583  1.00 16.94           C  
ATOM    688  NH1 ARG A  99     -18.507  18.269   3.291  1.00 15.71           N  
ATOM    689  NH2 ARG A  99     -18.309  16.891   1.437  1.00 16.85           N  
ATOM    690  N   GLU A 100     -24.641  13.499   3.050  1.00 16.17           N  
ATOM    691  CA  GLU A 100     -25.841  13.493   2.227  1.00 19.05           C  
ATOM    692  C   GLU A 100     -27.087  13.198   3.081  1.00 21.35           C  
ATOM    693  O   GLU A 100     -28.181  13.746   2.803  1.00 18.89           O  
ATOM    694  CB  GLU A 100     -25.747  12.480   1.059  1.00 21.03           C  
ATOM    695  CG  GLU A 100     -27.004  12.401   0.141  1.00 23.81           C  
ATOM    696  CD  GLU A 100     -26.951  11.372  -1.002  1.00 32.48           C  
ATOM    697  OE1 GLU A 100     -25.867  10.835  -1.353  1.00 28.53           O  
ATOM    698  OE2 GLU A 100     -28.036  11.086  -1.623  1.00 33.83           O  
ATOM    699  N   GLU A 101     -26.955  12.286   4.037  1.00 22.05           N  
ATOM    700  CA  GLU A 101     -28.071  11.890   4.926  1.00 28.53           C  
ATOM    701  C   GLU A 101     -28.364  12.857   6.046  1.00 35.91           C  
ATOM    702  O   GLU A 101     -29.472  12.845   6.574  1.00 32.64           O  
ATOM    703  CB  GLU A 101     -27.856  10.520   5.548  1.00 29.63           C  
ATOM    704  CG  GLU A 101     -27.627   9.378   4.562  1.00 35.35           C  
ATOM    705  CD  GLU A 101     -28.657   9.364   3.432  1.00 43.29           C  
ATOM    706  OE1 GLU A 101     -29.856   9.510   3.734  1.00 44.65           O  
ATOM    707  OE2 GLU A 101     -28.263   9.258   2.240  1.00 47.57           O  
ATOM    708  N   SER A 102     -27.389  13.686   6.416  1.00 37.62           N  
ATOM    709  CA  SER A 102     -27.512  14.482   7.609  1.00 43.42           C  
ATOM    710  C   SER A 102     -28.501  15.546   7.194  1.00 44.61           C  
ATOM    711  O   SER A 102     -28.551  15.952   6.045  1.00 51.60           O  
ATOM    712  CB  SER A 102     -26.141  15.005   8.077  1.00 42.74           C  
ATOM    713  OG  SER A 102     -25.266  13.874   8.312  1.00 43.10           O  
ATOM    714  N   GLY A 103     -29.384  15.917   8.097  1.00 48.12           N  
ATOM    715  CA  GLY A 103     -30.460  16.827   7.710  1.00 43.45           C  
ATOM    716  C   GLY A 103     -31.745  16.166   7.230  1.00 41.10           C  
ATOM    717  O   GLY A 103     -32.767  16.824   7.256  1.00 40.65           O  
ATOM    718  N   LYS A 104     -31.721  14.899   6.792  1.00 37.06           N  
ATOM    719  CA  LYS A 104     -32.967  14.115   6.630  1.00 33.57           C  
ATOM    720  C   LYS A 104     -33.617  13.723   7.961  1.00 36.72           C  
ATOM    721  O   LYS A 104     -32.927  13.440   8.928  1.00 37.72           O  
ATOM    722  CB  LYS A 104     -32.734  12.836   5.834  1.00 29.05           C  
ATOM    723  CG  LYS A 104     -32.444  13.179   4.409  1.00 30.65           C  
ATOM    724  CD  LYS A 104     -32.102  11.968   3.623  1.00 29.14           C  
ATOM    725  CE  LYS A 104     -31.655  12.400   2.219  1.00 30.29           C  
ATOM    726  NZ  LYS A 104     -31.133  11.165   1.634  1.00 29.66           N  
ATOM    727  N   PRO A 105     -34.961  13.624   7.983  1.00 39.42           N  
ATOM    728  CA  PRO A 105     -35.648  13.382   9.242  1.00 37.34           C  
ATOM    729  C   PRO A 105     -35.214  12.062   9.905  1.00 36.31           C  
ATOM    730  O   PRO A 105     -35.223  11.003   9.269  1.00 35.71           O  
ATOM    731  CB  PRO A 105     -37.139  13.384   8.843  1.00 40.06           C  
ATOM    732  CG  PRO A 105     -37.158  13.096   7.386  1.00 43.37           C  
ATOM    733  CD  PRO A 105     -35.893  13.698   6.837  1.00 40.11           C  
ATOM    734  N   GLY A 106     -34.769  12.155  11.166  1.00 34.44           N  
ATOM    735  CA  GLY A 106     -34.272  10.993  11.906  1.00 35.65           C  
ATOM    736  C   GLY A 106     -32.829  10.552  11.634  1.00 33.81           C  
ATOM    737  O   GLY A 106     -32.371   9.560  12.204  1.00 33.97           O  
ATOM    738  N   ALA A 107     -32.119  11.259  10.764  1.00 31.39           N  
ATOM    739  CA  ALA A 107     -30.746  10.842  10.374  1.00 31.93           C  
ATOM    740  C   ALA A 107     -29.798  10.635  11.555  1.00 30.04           C  
ATOM    741  O   ALA A 107     -28.986   9.691  11.543  1.00 28.73           O  
ATOM    742  CB  ALA A 107     -30.153  11.878   9.433  1.00 31.36           C  
ATOM    743  N   HIS A 108     -29.899  11.486  12.592  1.00 28.83           N  
ATOM    744  CA  HIS A 108     -29.026  11.346  13.784  1.00 29.08           C  
ATOM    745  C   HIS A 108     -29.737  10.811  15.030  1.00 30.19           C  
ATOM    746  O   HIS A 108     -29.207  10.930  16.090  1.00 26.78           O  
ATOM    747  CB  HIS A 108     -28.260  12.658  14.087  1.00 29.78           C  
ATOM    748  CG  HIS A 108     -27.314  13.069  12.989  1.00 30.04           C  
ATOM    749  ND1 HIS A 108     -27.060  14.377  12.669  1.00 34.07           N  
ATOM    750  CD2 HIS A 108     -26.643  12.339  12.076  1.00 35.39           C  
ATOM    751  CE1 HIS A 108     -26.269  14.443  11.620  1.00 33.17           C  
ATOM    752  NE2 HIS A 108     -26.000  13.217  11.235  1.00 35.21           N  
ATOM    753  N   VAL A 109     -30.899  10.208  14.901  1.00 31.57           N  
ATOM    754  CA  VAL A 109     -31.553   9.692  16.087  1.00 29.70           C  
ATOM    755  C   VAL A 109     -30.838   8.512  16.655  1.00 26.43           C  
ATOM    756  O   VAL A 109     -30.262   7.784  15.948  1.00 28.10           O  
ATOM    757  CB  VAL A 109     -33.009   9.254  15.865  1.00 20.00           C  
ATOM    758  CG1 VAL A 109     -33.921  10.428  15.647  1.00 20.00           C  
ATOM    759  CG2 VAL A 109     -33.095   8.230  14.773  1.00 20.00           C  
ATOM    760  N   THR A 110     -30.909   8.353  17.953  1.00 25.47           N  
ATOM    761  CA  THR A 110     -30.361   7.221  18.634  1.00 25.42           C  
ATOM    762  C   THR A 110     -31.498   6.396  19.139  1.00 26.65           C  
ATOM    763  O   THR A 110     -32.196   6.862  20.017  1.00 24.88           O  
ATOM    764  CB  THR A 110     -29.413   7.656  19.747  1.00 30.61           C  
ATOM    765  OG1 THR A 110     -28.324   8.325  19.108  1.00 33.00           O  
ATOM    766  CG2 THR A 110     -28.885   6.461  20.533  1.00 31.57           C  
ATOM    767  N   VAL A 111     -31.716   5.196  18.533  1.00 21.14           N  
ATOM    768  CA  VAL A 111     -32.831   4.331  18.867  1.00 19.81           C  
ATOM    769  C   VAL A 111     -32.397   2.888  18.780  1.00 19.18           C  
ATOM    770  O   VAL A 111     -31.409   2.517  18.055  1.00 18.06           O  
ATOM    771  CB  VAL A 111     -34.007   4.531  17.930  1.00 22.84           C  
ATOM    772  CG1 VAL A 111     -34.498   5.961  17.999  1.00 27.02           C  
ATOM    773  CG2 VAL A 111     -33.610   4.197  16.478  1.00 21.36           C  
ATOM    774  N   LYS A 112     -33.094   2.063  19.547  1.00 16.18           N  
ATOM    775  CA  LYS A 112     -32.773   0.626  19.641  1.00 16.07           C  
ATOM    776  C   LYS A 112     -33.679  -0.179  18.700  1.00 13.58           C  
ATOM    777  O   LYS A 112     -33.576  -1.384  18.640  1.00 14.48           O  
ATOM    778  CB  LYS A 112     -32.961   0.104  21.078  1.00 17.53           C  
ATOM    779  CG  LYS A 112     -32.074   0.828  22.086  1.00 21.44           C  
ATOM    780  CD  LYS A 112     -32.209   0.257  23.472  1.00 26.66           C  
ATOM    781  CE  LYS A 112     -31.206   0.985  24.353  1.00 30.74           C  
ATOM    782  NZ  LYS A 112     -31.642   0.764  25.759  1.00 36.32           N  
ATOM    783  N   LYS A 113     -34.567   0.509  18.025  1.00 14.01           N  
ATOM    784  CA  LYS A 113     -35.628  -0.134  17.278  1.00 16.68           C  
ATOM    785  C   LYS A 113     -35.455   0.132  15.804  1.00 14.32           C  
ATOM    786  O   LYS A 113     -35.251   1.286  15.404  1.00 15.00           O  
ATOM    787  CB  LYS A 113     -36.974   0.414  17.709  1.00 16.97           C  
ATOM    788  CG  LYS A 113     -38.143  -0.434  17.261  1.00 19.59           C  
ATOM    789  CD  LYS A 113     -39.386   0.332  17.679  1.00 23.88           C  
ATOM    790  CE  LYS A 113     -40.570  -0.496  17.992  1.00 28.30           C  
ATOM    791  NZ  LYS A 113     -41.643   0.502  18.316  1.00 30.80           N  
ATOM    792  N   LEU A 114     -35.641  -0.935  15.020  1.00 13.57           N  
ATOM    793  CA  LEU A 114     -35.472  -0.899  13.558  1.00 13.06           C  
ATOM    794  C   LEU A 114     -36.799  -1.299  12.889  1.00 12.59           C  
ATOM    795  O   LEU A 114     -37.334  -2.332  13.234  1.00 13.24           O  
ATOM    796  CB  LEU A 114     -34.437  -1.982  13.203  1.00 13.34           C  
ATOM    797  CG  LEU A 114     -33.962  -2.142  11.750  1.00 13.82           C  
ATOM    798  CD1 LEU A 114     -32.960  -1.043  11.448  1.00 13.72           C  
ATOM    799  CD2 LEU A 114     -33.383  -3.511  11.517  1.00 15.84           C  
ATOM    800  N   PHE A 115     -37.261  -0.493  11.950  1.00 12.47           N  
ATOM    801  CA  PHE A 115     -38.307  -0.830  10.962  1.00 12.38           C  
ATOM    802  C   PHE A 115     -37.739  -1.629   9.808  1.00 12.53           C  
ATOM    803  O   PHE A 115     -36.674  -1.292   9.277  1.00 12.51           O  
ATOM    804  CB  PHE A 115     -38.847   0.489  10.420  1.00 13.71           C  
ATOM    805  CG  PHE A 115     -39.803   0.370   9.269  1.00 14.77           C  
ATOM    806  CD1 PHE A 115     -39.349   0.327   7.934  1.00 14.22           C  
ATOM    807  CD2 PHE A 115     -41.156   0.380   9.509  1.00 15.76           C  
ATOM    808  CE1 PHE A 115     -40.254   0.219   6.878  1.00 15.72           C  
ATOM    809  CE2 PHE A 115     -42.060   0.322   8.440  1.00 17.67           C  
ATOM    810  CZ  PHE A 115     -41.593   0.264   7.136  1.00 16.63           C  
ATOM    811  N   VAL A 116     -38.414  -2.726   9.469  1.00 12.67           N  
ATOM    812  CA  VAL A 116     -38.090  -3.614   8.379  1.00 12.57           C  
ATOM    813  C   VAL A 116     -39.352  -3.687   7.477  1.00 13.84           C  
ATOM    814  O   VAL A 116     -40.385  -4.171   7.933  1.00 12.36           O  
ATOM    815  CB  VAL A 116     -37.729  -4.962   8.886  1.00 12.88           C  
ATOM    816  CG1 VAL A 116     -37.307  -5.845   7.719  1.00 13.43           C  
ATOM    817  CG2 VAL A 116     -36.613  -4.901   9.945  1.00 13.00           C  
ATOM    818  N   GLY A 117     -39.261  -3.136   6.269  1.00 13.88           N  
ATOM    819  CA  GLY A 117     -40.335  -3.146   5.298  1.00 15.68           C  
ATOM    820  C   GLY A 117     -40.011  -3.948   4.080  1.00 15.29           C  
ATOM    821  O   GLY A 117     -38.883  -4.384   3.915  1.00 12.57           O  
ATOM    822  N   GLY A 118     -41.038  -4.178   3.263  1.00 14.34           N  
ATOM    823  CA  GLY A 118     -40.897  -4.966   2.047  1.00 14.14           C  
ATOM    824  C   GLY A 118     -40.885  -6.440   2.310  1.00 13.25           C  
ATOM    825  O   GLY A 118     -40.497  -7.211   1.420  1.00 13.74           O  
ATOM    826  N   ILE A 119     -41.363  -6.882   3.463  1.00 11.45           N  
ATOM    827  CA  ILE A 119     -41.303  -8.276   3.798  1.00 12.42           C  
ATOM    828  C   ILE A 119     -42.601  -9.049   3.457  1.00 12.23           C  
ATOM    829  O   ILE A 119     -42.655 -10.235   3.615  1.00 14.33           O  
ATOM    830  CB  ILE A 119     -40.892  -8.543   5.252  1.00 12.58           C  
ATOM    831  CG1 ILE A 119     -41.873  -7.922   6.244  1.00 12.50           C  
ATOM    832  CG2 ILE A 119     -39.384  -8.192   5.440  1.00 13.66           C  
ATOM    833  CD1 ILE A 119     -41.477  -8.120   7.737  1.00 13.20           C  
ATOM    834  N   LYS A 120     -43.573  -8.351   2.911  1.00 14.51           N  
ATOM    835  CA  LYS A 120     -44.864  -8.944   2.426  1.00 17.32           C  
ATOM    836  C   LYS A 120     -45.563  -9.794   3.466  1.00 17.71           C  
ATOM    837  O   LYS A 120     -45.407  -9.561   4.683  1.00 15.63           O  
ATOM    838  CB  LYS A 120     -44.627  -9.648   1.063  1.00 18.02           C  
ATOM    839  CG  LYS A 120     -44.001  -8.717   0.048  1.00 19.51           C  
ATOM    840  CD  LYS A 120     -44.197  -9.297  -1.361  1.00 23.04           C  
ATOM    841  CE  LYS A 120     -43.530  -8.419  -2.411  1.00 24.18           C  
ATOM    842  NZ  LYS A 120     -43.841  -8.823  -3.808  1.00 31.44           N  
ATOM    843  N   GLU A 121     -46.242 -10.853   3.024  1.00 21.34           N  
ATOM    844  CA  GLU A 121     -47.119 -11.639   3.900  1.00 22.48           C  
ATOM    845  C   GLU A 121     -46.618 -12.964   4.378  1.00 23.38           C  
ATOM    846  O   GLU A 121     -47.280 -13.570   5.203  1.00 29.54           O  
ATOM    847  CB  GLU A 121     -48.475 -11.868   3.207  1.00 25.68           C  
ATOM    848  CG  GLU A 121     -49.285 -10.597   3.048  1.00 26.05           C  
ATOM    849  CD  GLU A 121     -50.647 -10.885   2.377  1.00 32.80           C  
ATOM    850  OE1 GLU A 121     -51.436 -11.693   2.901  1.00 37.69           O  
ATOM    851  OE2 GLU A 121     -50.914 -10.310   1.324  1.00 42.22           O  
ATOM    852  N   ASP A 122     -45.476 -13.435   3.917  1.00 21.99           N  
ATOM    853  CA  ASP A 122     -44.986 -14.783   4.292  1.00 22.08           C  
ATOM    854  C   ASP A 122     -43.793 -14.672   5.245  1.00 22.23           C  
ATOM    855  O   ASP A 122     -43.157 -15.674   5.555  1.00 24.13           O  
ATOM    856  CB  ASP A 122     -44.588 -15.556   3.038  1.00 23.24           C  
ATOM    857  CG  ASP A 122     -43.525 -14.806   2.205  1.00 27.33           C  
ATOM    858  OD1 ASP A 122     -43.221 -13.631   2.549  1.00 23.43           O  
ATOM    859  OD2 ASP A 122     -42.967 -15.374   1.254  1.00 25.95           O  
ATOM    860  N   THR A 123     -43.441 -13.447   5.660  1.00 19.60           N  
ATOM    861  CA  THR A 123     -42.335 -13.261   6.587  1.00 18.64           C  
ATOM    862  C   THR A 123     -42.826 -13.221   8.049  1.00 19.64           C  
ATOM    863  O   THR A 123     -43.608 -12.394   8.429  1.00 20.59           O  
ATOM    864  CB  THR A 123     -41.504 -12.009   6.234  1.00 16.24           C  
ATOM    865  OG1 THR A 123     -41.075 -12.102   4.867  1.00 16.14           O  
ATOM    866  CG2 THR A 123     -40.307 -11.861   7.148  1.00 16.28           C  
ATOM    867  N   GLU A 124     -42.239 -14.104   8.860  1.00 20.43           N  
ATOM    868  CA  GLU A 124     -42.583 -14.306  10.250  1.00 22.57           C  
ATOM    869  C   GLU A 124     -41.466 -13.736  11.151  1.00 22.55           C  
ATOM    870  O   GLU A 124     -40.336 -13.449  10.738  1.00 20.99           O  
ATOM    871  CB  GLU A 124     -42.670 -15.809  10.538  1.00 26.22           C  
ATOM    872  CG  GLU A 124     -43.667 -16.587   9.677  1.00 30.62           C  
ATOM    873  CD  GLU A 124     -45.116 -16.186   9.885  1.00 34.69           C  
ATOM    874  OE1 GLU A 124     -45.510 -15.659  10.955  1.00 41.53           O  
ATOM    875  OE2 GLU A 124     -45.884 -16.368   8.929  1.00 41.80           O  
ATOM    876  N   GLU A 125     -41.796 -13.709  12.413  1.00 22.98           N  
ATOM    877  CA  GLU A 125     -40.895 -13.323  13.493  1.00 24.18           C  
ATOM    878  C   GLU A 125     -39.605 -14.079  13.437  1.00 23.01           C  
ATOM    879  O   GLU A 125     -38.533 -13.469  13.531  1.00 21.73           O  
ATOM    880  CB  GLU A 125     -41.619 -13.578  14.823  1.00 30.21           C  
ATOM    881  CG  GLU A 125     -41.415 -12.598  15.917  1.00 36.99           C  
ATOM    882  CD  GLU A 125     -42.363 -12.881  17.096  1.00 35.70           C  
ATOM    883  OE1 GLU A 125     -43.547 -12.471  17.038  1.00 39.10           O  
ATOM    884  OE2 GLU A 125     -41.887 -13.472  18.066  1.00 39.72           O  
ATOM    885  N   HIS A 126     -39.667 -15.402  13.277  1.00 21.30           N  
ATOM    886  CA  HIS A 126     -38.463 -16.204  13.201  1.00 23.06           C  
ATOM    887  C   HIS A 126     -37.516 -15.885  12.013  1.00 20.62           C  
ATOM    888  O   HIS A 126     -36.308 -16.107  12.082  1.00 22.03           O  
ATOM    889  CB  HIS A 126     -38.775 -17.712  13.224  1.00 26.05           C  
ATOM    890  CG  HIS A 126     -39.429 -18.243  11.983  1.00 27.55           C  
ATOM    891  ND1 HIS A 126     -40.802 -18.296  11.828  1.00 33.22           N  
ATOM    892  CD2 HIS A 126     -38.902 -18.841  10.888  1.00 28.53           C  
ATOM    893  CE1 HIS A 126     -41.090 -18.860  10.665  1.00 30.38           C  
ATOM    894  NE2 HIS A 126     -39.954 -19.182  10.070  1.00 29.90           N  
ATOM    895  N   HIS A 127     -38.062 -15.412  10.907  1.00 19.70           N  
ATOM    896  CA  HIS A 127     -37.197 -15.003   9.785  1.00 17.19           C  
ATOM    897  C   HIS A 127     -36.449 -13.740  10.202  1.00 15.75           C  
ATOM    898  O   HIS A 127     -35.294 -13.666   9.977  1.00 17.40           O  
ATOM    899  CB  HIS A 127     -37.976 -14.741   8.546  1.00 17.74           C  
ATOM    900  CG  HIS A 127     -38.627 -15.951   7.965  1.00 19.95           C  
ATOM    901  ND1 HIS A 127     -39.989 -16.110   7.956  1.00 21.17           N  
ATOM    902  CD2 HIS A 127     -38.122 -17.042   7.359  1.00 21.19           C  
ATOM    903  CE1 HIS A 127     -40.315 -17.230   7.348  1.00 20.43           C  
ATOM    904  NE2 HIS A 127     -39.194 -17.797   6.947  1.00 21.44           N  
ATOM    905  N   LEU A 128     -37.108 -12.787  10.833  1.00 16.80           N  
ATOM    906  CA  LEU A 128     -36.412 -11.575  11.323  1.00 17.05           C  
ATOM    907  C   LEU A 128     -35.395 -11.865  12.387  1.00 20.18           C  
ATOM    908  O   LEU A 128     -34.272 -11.345  12.334  1.00 18.27           O  
ATOM    909  CB  LEU A 128     -37.381 -10.488  11.717  1.00 15.99           C  
ATOM    910  CG  LEU A 128     -38.365  -9.991  10.697  1.00 15.79           C  
ATOM    911  CD1 LEU A 128     -39.102  -8.736  11.124  1.00 17.87           C  
ATOM    912  CD2 LEU A 128     -37.837  -9.755   9.292  1.00 17.12           C  
ATOM    913  N   ARG A 129     -35.701 -12.825  13.264  1.00 21.31           N  
ATOM    914  CA  ARG A 129     -34.716 -13.270  14.243  1.00 21.08           C  
ATOM    915  C   ARG A 129     -33.480 -13.836  13.618  1.00 20.91           C  
ATOM    916  O   ARG A 129     -32.353 -13.426  13.949  1.00 20.11           O  
ATOM    917  CB  ARG A 129     -35.360 -14.226  15.275  1.00 24.65           C  
ATOM    918  CG  ARG A 129     -34.439 -14.710  16.425  1.00 28.59           C  
ATOM    919  CD  ARG A 129     -35.237 -15.494  17.502  1.00 29.84           C  
ATOM    920  NE  ARG A 129     -36.344 -14.750  18.079  1.00 31.65           N  
ATOM    921  CZ  ARG A 129     -36.286 -13.792  19.028  1.00 37.44           C  
ATOM    922  NH1 ARG A 129     -35.131 -13.408  19.593  1.00 36.66           N  
ATOM    923  NH2 ARG A 129     -37.430 -13.196  19.430  1.00 35.60           N  
ATOM    924  N   ASP A 130     -33.661 -14.806  12.732  1.00 23.97           N  
ATOM    925  CA  ASP A 130     -32.552 -15.493  12.144  1.00 24.43           C  
ATOM    926  C   ASP A 130     -31.644 -14.521  11.355  1.00 23.20           C  
ATOM    927  O   ASP A 130     -30.419 -14.634  11.426  1.00 24.62           O  
ATOM    928  CB  ASP A 130     -33.020 -16.614  11.224  1.00 30.53           C  
ATOM    929  CG  ASP A 130     -33.764 -17.746  11.983  1.00 35.46           C  
ATOM    930  OD1 ASP A 130     -33.875 -17.728  13.247  1.00 37.62           O  
ATOM    931  OD2 ASP A 130     -34.273 -18.638  11.280  1.00 40.61           O  
ATOM    932  N   TYR A 131     -32.250 -13.614  10.580  1.00 18.00           N  
ATOM    933  CA  TYR A 131     -31.484 -12.594   9.839  1.00 17.05           C  
ATOM    934  C   TYR A 131     -30.761 -11.592  10.757  1.00 16.37           C  
ATOM    935  O   TYR A 131     -29.591 -11.269  10.525  1.00 16.10           O  
ATOM    936  CB  TYR A 131     -32.386 -11.812   8.868  1.00 16.07           C  
ATOM    937  CG  TYR A 131     -31.590 -10.953   7.942  1.00 15.91           C  
ATOM    938  CD1 TYR A 131     -30.940 -11.489   6.825  1.00 16.69           C  
ATOM    939  CD2 TYR A 131     -31.429  -9.588   8.213  1.00 14.66           C  
ATOM    940  CE1 TYR A 131     -30.153 -10.700   6.000  1.00 16.41           C  
ATOM    941  CE2 TYR A 131     -30.610  -8.787   7.409  1.00 15.07           C  
ATOM    942  CZ  TYR A 131     -30.010  -9.340   6.293  1.00 15.19           C  
ATOM    943  OH  TYR A 131     -29.259  -8.540   5.492  1.00 17.99           O  
ATOM    944  N   PHE A 132     -31.458 -11.070  11.774  1.00 16.13           N  
ATOM    945  CA  PHE A 132     -30.903  -9.931  12.537  1.00 17.44           C  
ATOM    946  C   PHE A 132     -30.073 -10.248  13.778  1.00 18.09           C  
ATOM    947  O   PHE A 132     -29.297  -9.396  14.210  1.00 18.19           O  
ATOM    948  CB  PHE A 132     -31.984  -8.914  12.892  1.00 15.50           C  
ATOM    949  CG  PHE A 132     -32.433  -8.104  11.721  1.00 16.26           C  
ATOM    950  CD1 PHE A 132     -31.532  -7.208  11.104  1.00 15.77           C  
ATOM    951  CD2 PHE A 132     -33.691  -8.288  11.150  1.00 15.03           C  
ATOM    952  CE1 PHE A 132     -31.909  -6.468  10.004  1.00 14.29           C  
ATOM    953  CE2 PHE A 132     -34.054  -7.555  10.034  1.00 14.97           C  
ATOM    954  CZ  PHE A 132     -33.167  -6.645   9.477  1.00 13.90           C  
ATOM    955  N   GLU A 133     -30.181 -11.452  14.315  1.00 20.08           N  
ATOM    956  CA  GLU A 133     -29.490 -11.727  15.569  1.00 23.02           C  
ATOM    957  C   GLU A 133     -27.975 -11.754  15.407  1.00 23.93           C  
ATOM    958  O   GLU A 133     -27.288 -11.520  16.373  1.00 24.53           O  
ATOM    959  CB  GLU A 133     -30.011 -13.006  16.243  1.00 25.67           C  
ATOM    960  CG  GLU A 133     -29.620 -14.271  15.554  1.00 28.84           C  
ATOM    961  CD  GLU A 133     -30.342 -15.471  16.165  1.00 31.21           C  
ATOM    962  OE1 GLU A 133     -30.913 -15.362  17.290  1.00 31.99           O  
ATOM    963  OE2 GLU A 133     -30.315 -16.503  15.495  1.00 31.73           O  
ATOM    964  N   GLU A 134     -27.423 -11.962  14.214  1.00 24.92           N  
ATOM    965  CA  GLU A 134     -25.997 -11.735  14.095  1.00 28.44           C  
ATOM    966  C   GLU A 134     -25.546 -10.282  14.350  1.00 31.03           C  
ATOM    967  O   GLU A 134     -24.372 -10.067  14.607  1.00 27.45           O  
ATOM    968  CB  GLU A 134     -25.465 -12.218  12.765  1.00 35.47           C  
ATOM    969  CG  GLU A 134     -25.840 -11.389  11.547  1.00 37.86           C  
ATOM    970  CD  GLU A 134     -25.234 -12.014  10.296  1.00 44.17           C  
ATOM    971  OE1 GLU A 134     -25.792 -13.043   9.806  1.00 39.42           O  
ATOM    972  OE2 GLU A 134     -24.185 -11.490   9.842  1.00 44.46           O  
ATOM    973  N   TYR A 135     -26.440  -9.289  14.246  1.00 25.74           N  
ATOM    974  CA  TYR A 135     -26.032  -7.912  14.419  1.00 25.07           C  
ATOM    975  C   TYR A 135     -26.034  -7.473  15.894  1.00 23.78           C  
ATOM    976  O   TYR A 135     -25.410  -6.490  16.251  1.00 24.01           O  
ATOM    977  CB  TYR A 135     -26.917  -6.982  13.641  1.00 22.07           C  
ATOM    978  CG  TYR A 135     -26.807  -7.100  12.148  1.00 22.14           C  
ATOM    979  CD1 TYR A 135     -27.637  -7.982  11.432  1.00 24.31           C  
ATOM    980  CD2 TYR A 135     -25.967  -6.274  11.439  1.00 23.16           C  
ATOM    981  CE1 TYR A 135     -27.560  -8.088  10.055  1.00 24.54           C  
ATOM    982  CE2 TYR A 135     -25.919  -6.307  10.059  1.00 24.46           C  
ATOM    983  CZ  TYR A 135     -26.714  -7.217   9.364  1.00 26.53           C  
ATOM    984  OH  TYR A 135     -26.663  -7.287   7.991  1.00 26.52           O  
ATOM    985  N   GLY A 136     -26.776  -8.167  16.722  1.00 23.86           N  
ATOM    986  CA  GLY A 136     -26.768  -7.911  18.140  1.00 24.87           C  
ATOM    987  C   GLY A 136     -27.874  -8.637  18.863  1.00 25.74           C  
ATOM    988  O   GLY A 136     -28.658  -9.373  18.279  1.00 25.81           O  
ATOM    989  N   LYS A 137     -27.928  -8.412  20.170  1.00 25.21           N  
ATOM    990  CA  LYS A 137     -28.905  -9.016  21.020  1.00 27.17           C  
ATOM    991  C   LYS A 137     -30.281  -8.396  20.766  1.00 22.90           C  
ATOM    992  O   LYS A 137     -30.500  -7.186  20.912  1.00 20.10           O  
ATOM    993  CB  LYS A 137     -28.495  -8.880  22.518  1.00 33.63           C  
ATOM    994  CG  LYS A 137     -29.254  -9.805  23.474  1.00 42.15           C  
ATOM    995  CD  LYS A 137     -30.656  -9.290  23.795  1.00 49.13           C  
ATOM    996  CE  LYS A 137     -31.395 -10.115  24.839  1.00 56.58           C  
ATOM    997  NZ  LYS A 137     -31.200  -9.496  26.179  1.00 60.26           N  
ATOM    998  N   ILE A 138     -31.234  -9.248  20.398  1.00 21.88           N  
ATOM    999  CA  ILE A 138     -32.601  -8.812  20.137  1.00 22.29           C  
ATOM   1000  C   ILE A 138     -33.477  -8.896  21.403  1.00 23.34           C  
ATOM   1001  O   ILE A 138     -33.515  -9.912  22.041  1.00 23.98           O  
ATOM   1002  CB  ILE A 138     -33.247  -9.646  19.016  1.00 21.27           C  
ATOM   1003  CG1 ILE A 138     -32.470  -9.410  17.695  1.00 23.02           C  
ATOM   1004  CG2 ILE A 138     -34.713  -9.283  18.889  1.00 20.98           C  
ATOM   1005  CD1 ILE A 138     -32.795 -10.418  16.611  1.00 22.56           C  
ATOM   1006  N   ASP A 139     -34.147  -7.832  21.763  1.00 24.62           N  
ATOM   1007  CA  ASP A 139     -35.074  -7.915  22.869  1.00 28.15           C  
ATOM   1008  C   ASP A 139     -36.487  -8.244  22.428  1.00 30.41           C  
ATOM   1009  O   ASP A 139     -37.119  -9.054  23.063  1.00 25.57           O  
ATOM   1010  CB  ASP A 139     -35.059  -6.632  23.690  1.00 30.03           C  
ATOM   1011  CG  ASP A 139     -33.810  -6.527  24.552  1.00 32.10           C  
ATOM   1012  OD1 ASP A 139     -33.174  -7.592  24.757  1.00 38.28           O  
ATOM   1013  OD2 ASP A 139     -33.461  -5.396  24.984  1.00 42.35           O  
ATOM   1014  N   THR A 140     -36.993  -7.613  21.373  1.00 25.60           N  
ATOM   1015  CA  THR A 140     -38.352  -7.924  20.899  1.00 27.28           C  
ATOM   1016  C   THR A 140     -38.437  -7.817  19.340  1.00 25.61           C  
ATOM   1017  O   THR A 140     -37.673  -7.018  18.707  1.00 18.94           O  
ATOM   1018  CB  THR A 140     -39.418  -7.017  21.560  1.00 30.02           C  
ATOM   1019  OG1 THR A 140     -39.382  -5.731  21.014  1.00 36.05           O  
ATOM   1020  CG2 THR A 140     -39.178  -6.782  23.032  1.00 34.84           C  
ATOM   1021  N   ILE A 141     -39.320  -8.630  18.753  1.00 21.87           N  
ATOM   1022  CA  ILE A 141     -39.658  -8.594  17.313  1.00 21.20           C  
ATOM   1023  C   ILE A 141     -41.174  -8.493  17.187  1.00 24.37           C  
ATOM   1024  O   ILE A 141     -41.882  -9.240  17.884  1.00 22.10           O  
ATOM   1025  CB  ILE A 141     -39.172  -9.855  16.592  1.00 20.82           C  
ATOM   1026  CG1 ILE A 141     -37.661 -10.029  16.767  1.00 20.21           C  
ATOM   1027  CG2 ILE A 141     -39.596  -9.834  15.104  1.00 20.98           C  
ATOM   1028  CD1 ILE A 141     -37.152 -11.377  16.359  1.00 20.58           C  
ATOM   1029  N   GLU A 142     -41.653  -7.571  16.356  1.00 21.64           N  
ATOM   1030  CA  GLU A 142     -43.088  -7.373  16.136  1.00 26.33           C  
ATOM   1031  C   GLU A 142     -43.382  -7.395  14.644  1.00 26.82           C  
ATOM   1032  O   GLU A 142     -42.934  -6.505  13.956  1.00 26.79           O  
ATOM   1033  CB  GLU A 142     -43.513  -6.031  16.713  1.00 29.27           C  
ATOM   1034  CG  GLU A 142     -45.011  -5.758  16.672  1.00 34.52           C  
ATOM   1035  CD  GLU A 142     -45.413  -4.492  17.409  1.00 37.95           C  
ATOM   1036  OE1 GLU A 142     -44.505  -3.729  17.842  1.00 35.76           O  
ATOM   1037  OE2 GLU A 142     -46.649  -4.252  17.555  1.00 36.09           O  
ATOM   1038  N   ILE A 143     -44.087  -8.417  14.133  1.00 25.06           N  
ATOM   1039  CA  ILE A 143     -44.649  -8.382  12.750  1.00 24.15           C  
ATOM   1040  C   ILE A 143     -46.042  -7.677  12.740  1.00 25.36           C  
ATOM   1041  O   ILE A 143     -46.953  -8.063  13.500  1.00 24.50           O  
ATOM   1042  CB  ILE A 143     -44.790  -9.826  12.184  1.00 26.37           C  
ATOM   1043  CG1 ILE A 143     -43.454 -10.578  12.155  1.00 27.37           C  
ATOM   1044  CG2 ILE A 143     -45.375  -9.808  10.783  1.00 28.35           C  
ATOM   1045  CD1 ILE A 143     -42.434 -10.060  11.134  1.00 26.74           C  
ATOM   1046  N   ILE A 144     -46.236  -6.639  11.935  1.00 21.33           N  
ATOM   1047  CA  ILE A 144     -47.425  -5.871  12.029  1.00 22.62           C  
ATOM   1048  C   ILE A 144     -48.504  -6.570  11.150  1.00 24.40           C  
ATOM   1049  O   ILE A 144     -48.233  -6.973   9.998  1.00 21.99           O  
ATOM   1050  CB  ILE A 144     -47.200  -4.381  11.637  1.00 21.53           C  
ATOM   1051  CG1 ILE A 144     -46.103  -3.754  12.508  1.00 21.36           C  
ATOM   1052  CG2 ILE A 144     -48.497  -3.574  11.752  1.00 21.52           C  
ATOM   1053  CD1 ILE A 144     -46.420  -3.688  13.979  1.00 23.87           C  
ATOM   1054  N   THR A 145     -49.682  -6.782  11.733  1.00 26.55           N  
ATOM   1055  CA  THR A 145     -50.856  -7.329  11.017  1.00 25.15           C  
ATOM   1056  C   THR A 145     -52.029  -6.324  11.027  1.00 25.70           C  
ATOM   1057  O   THR A 145     -52.097  -5.447  11.872  1.00 25.37           O  
ATOM   1058  CB  THR A 145     -51.375  -8.567  11.676  1.00 28.08           C  
ATOM   1059  OG1 THR A 145     -51.740  -8.199  12.992  1.00 30.97           O  
ATOM   1060  CG2 THR A 145     -50.329  -9.679  11.717  1.00 28.17           C  
ATOM   1061  N   ASP A 146     -52.900  -6.416  10.016  1.00 21.95           N  
ATOM   1062  CA  ASP A 146     -54.092  -5.584   9.895  1.00 22.72           C  
ATOM   1063  C   ASP A 146     -55.038  -6.128  11.021  1.00 21.80           C  
ATOM   1064  O   ASP A 146     -55.264  -7.303  11.115  1.00 20.84           O  
ATOM   1065  CB  ASP A 146     -54.643  -5.765   8.485  1.00 22.20           C  
ATOM   1066  CG  ASP A 146     -55.903  -5.009   8.227  1.00 22.88           C  
ATOM   1067  OD1 ASP A 146     -56.960  -5.229   8.835  1.00 18.87           O  
ATOM   1068  OD2 ASP A 146     -55.878  -4.138   7.386  1.00 28.03           O  
ATOM   1069  N   ARG A 147     -55.519  -5.262  11.879  1.00 27.14           N  
ATOM   1070  CA  ARG A 147     -56.407  -5.686  13.005  1.00 34.25           C  
ATOM   1071  C   ARG A 147     -57.706  -6.350  12.478  1.00 28.22           C  
ATOM   1072  O   ARG A 147     -58.184  -7.336  13.044  1.00 27.86           O  
ATOM   1073  CB  ARG A 147     -56.751  -4.501  13.962  1.00 42.03           C  
ATOM   1074  CG  ARG A 147     -56.647  -3.107  13.332  1.00 48.83           C  
ATOM   1075  CD  ARG A 147     -57.362  -1.957  14.025  1.00 54.27           C  
ATOM   1076  NE  ARG A 147     -57.233  -1.857  15.475  1.00 61.23           N  
ATOM   1077  CZ  ARG A 147     -57.830  -0.912  16.220  1.00 69.98           C  
ATOM   1078  NH1 ARG A 147     -58.604   0.025  15.652  1.00 72.85           N  
ATOM   1079  NH2 ARG A 147     -57.659  -0.895  17.548  1.00 64.71           N  
ATOM   1080  N   GLN A 148     -58.225  -5.836  11.353  1.00 20.36           N  
ATOM   1081  CA  GLN A 148     -59.484  -6.363  10.797  1.00 19.00           C  
ATOM   1082  C   GLN A 148     -59.337  -7.683  10.078  1.00 18.04           C  
ATOM   1083  O   GLN A 148     -60.058  -8.641  10.377  1.00 18.53           O  
ATOM   1084  CB  GLN A 148     -60.142  -5.348   9.875  1.00 17.49           C  
ATOM   1085  CG  GLN A 148     -60.613  -4.177  10.651  1.00 19.77           C  
ATOM   1086  CD  GLN A 148     -61.248  -3.122   9.772  1.00 25.06           C  
ATOM   1087  OE1 GLN A 148     -61.275  -3.196   8.503  1.00 25.00           O  
ATOM   1088  NE2 GLN A 148     -61.806  -2.130  10.437  1.00 30.79           N  
ATOM   1089  N   SER A 149     -58.422  -7.761   9.133  1.00 17.17           N  
ATOM   1090  CA  SER A 149     -58.297  -8.963   8.283  1.00 17.91           C  
ATOM   1091  C   SER A 149     -57.423 -10.042   8.863  1.00 17.39           C  
ATOM   1092  O   SER A 149     -57.407 -11.125   8.339  1.00 19.43           O  
ATOM   1093  CB  SER A 149     -57.699  -8.574   6.930  1.00 17.94           C  
ATOM   1094  OG  SER A 149     -56.299  -8.316   7.052  1.00 15.74           O  
ATOM   1095  N   GLY A 150     -56.577  -9.707   9.813  1.00 17.46           N  
ATOM   1096  CA  GLY A 150     -55.607 -10.640  10.328  1.00 21.72           C  
ATOM   1097  C   GLY A 150     -54.296 -10.732   9.537  1.00 21.84           C  
ATOM   1098  O   GLY A 150     -53.322 -11.274  10.041  1.00 26.68           O  
ATOM   1099  N   LYS A 151     -54.258 -10.143   8.355  1.00 20.53           N  
ATOM   1100  CA  LYS A 151     -53.174 -10.384   7.444  1.00 24.81           C  
ATOM   1101  C   LYS A 151     -51.982  -9.479   7.755  1.00 23.93           C  
ATOM   1102  O   LYS A 151     -52.125  -8.289   8.127  1.00 20.86           O  
ATOM   1103  CB  LYS A 151     -53.606 -10.215   5.996  1.00 27.50           C  
ATOM   1104  CG  LYS A 151     -54.598 -11.300   5.573  1.00 29.20           C  
ATOM   1105  CD  LYS A 151     -55.395 -10.889   4.349  1.00 33.26           C  
ATOM   1106  CE  LYS A 151     -54.547 -10.974   3.107  1.00 37.67           C  
ATOM   1107  NZ  LYS A 151     -55.418 -10.925   1.929  1.00 35.81           N  
ATOM   1108  N   LYS A 152     -50.804 -10.072   7.565  1.00 22.62           N  
ATOM   1109  CA  LYS A 152     -49.540  -9.347   7.738  1.00 23.38           C  
ATOM   1110  C   LYS A 152     -49.554  -8.154   6.797  1.00 19.64           C  
ATOM   1111  O   LYS A 152     -50.005  -8.279   5.663  1.00 20.53           O  
ATOM   1112  CB  LYS A 152     -48.406 -10.295   7.408  1.00 25.84           C  
ATOM   1113  CG  LYS A 152     -48.210 -11.346   8.462  1.00 29.68           C  
ATOM   1114  CD  LYS A 152     -46.957 -12.161   8.175  1.00 35.21           C  
ATOM   1115  CE  LYS A 152     -46.828 -13.354   9.094  1.00 38.27           C  
ATOM   1116  NZ  LYS A 152     -47.678 -14.453   8.550  1.00 43.47           N  
ATOM   1117  N   ARG A 153     -49.118  -6.975   7.268  1.00 18.59           N  
ATOM   1118  CA  ARG A 153     -49.077  -5.774   6.448  1.00 18.49           C  
ATOM   1119  C   ARG A 153     -47.737  -5.479   5.665  1.00 19.84           C  
ATOM   1120  O   ARG A 153     -47.611  -4.445   5.003  1.00 17.64           O  
ATOM   1121  CB  ARG A 153     -49.405  -4.557   7.315  1.00 20.40           C  
ATOM   1122  CG  ARG A 153     -50.863  -4.580   7.843  1.00 22.36           C  
ATOM   1123  CD  ARG A 153     -51.168  -3.409   8.774  1.00 22.48           C  
ATOM   1124  NE  ARG A 153     -50.919  -2.178   8.078  1.00 24.77           N  
ATOM   1125  CZ  ARG A 153     -50.669  -0.988   8.629  1.00 26.09           C  
ATOM   1126  NH1 ARG A 153     -50.737  -0.767   9.941  1.00 27.10           N  
ATOM   1127  NH2 ARG A 153     -50.398   0.011   7.807  1.00 29.44           N  
ATOM   1128  N   GLY A 154     -46.752  -6.349   5.809  1.00 18.30           N  
ATOM   1129  CA  GLY A 154     -45.492  -6.228   5.045  1.00 18.13           C  
ATOM   1130  C   GLY A 154     -44.360  -5.452   5.708  1.00 16.72           C  
ATOM   1131  O   GLY A 154     -43.499  -4.978   5.033  1.00 14.14           O  
ATOM   1132  N   PHE A 155     -44.419  -5.328   7.019  1.00 16.29           N  
ATOM   1133  CA  PHE A 155     -43.387  -4.720   7.800  1.00 16.72           C  
ATOM   1134  C   PHE A 155     -43.453  -5.135   9.246  1.00 18.75           C  
ATOM   1135  O   PHE A 155     -44.467  -5.680   9.750  1.00 16.78           O  
ATOM   1136  CB  PHE A 155     -43.416  -3.182   7.627  1.00 18.04           C  
ATOM   1137  CG  PHE A 155     -44.597  -2.513   8.224  1.00 19.50           C  
ATOM   1138  CD1 PHE A 155     -45.849  -2.507   7.546  1.00 19.73           C  
ATOM   1139  CD2 PHE A 155     -44.502  -1.862   9.463  1.00 19.23           C  
ATOM   1140  CE1 PHE A 155     -46.954  -1.881   8.102  1.00 18.83           C  
ATOM   1141  CE2 PHE A 155     -45.633  -1.267  10.044  1.00 22.18           C  
ATOM   1142  CZ  PHE A 155     -46.863  -1.274   9.355  1.00 20.71           C  
ATOM   1143  N   GLY A 156     -42.342  -4.874   9.929  1.00 17.27           N  
ATOM   1144  CA  GLY A 156     -42.112  -5.303  11.288  1.00 18.33           C  
ATOM   1145  C   GLY A 156     -41.069  -4.413  11.952  1.00 17.70           C  
ATOM   1146  O   GLY A 156     -40.470  -3.566  11.295  1.00 14.49           O  
ATOM   1147  N   PHE A 157     -40.894  -4.621  13.250  1.00 18.35           N  
ATOM   1148  CA  PHE A 157     -39.888  -3.889  14.053  1.00 17.49           C  
ATOM   1149  C   PHE A 157     -39.070  -4.844  14.847  1.00 18.71           C  
ATOM   1150  O   PHE A 157     -39.592  -5.824  15.415  1.00 19.57           O  
ATOM   1151  CB  PHE A 157     -40.561  -2.882  14.992  1.00 17.82           C  
ATOM   1152  CG  PHE A 157     -41.339  -1.806  14.283  1.00 16.86           C  
ATOM   1153  CD1 PHE A 157     -42.672  -1.979  13.999  1.00 17.14           C  
ATOM   1154  CD2 PHE A 157     -40.766  -0.619  13.947  1.00 17.73           C  
ATOM   1155  CE1 PHE A 157     -43.386  -1.020  13.338  1.00 16.79           C  
ATOM   1156  CE2 PHE A 157     -41.477   0.404  13.353  1.00 16.44           C  
ATOM   1157  CZ  PHE A 157     -42.807   0.203  13.028  1.00 19.93           C  
ATOM   1158  N   VAL A 158     -37.745  -4.593  14.891  1.00 18.52           N  
ATOM   1159  CA  VAL A 158     -36.822  -5.410  15.654  1.00 16.56           C  
ATOM   1160  C   VAL A 158     -36.198  -4.427  16.653  1.00 17.36           C  
ATOM   1161  O   VAL A 158     -35.759  -3.344  16.229  1.00 16.13           O  
ATOM   1162  CB  VAL A 158     -35.734  -6.040  14.767  1.00 17.64           C  
ATOM   1163  CG1 VAL A 158     -34.752  -6.831  15.607  1.00 16.87           C  
ATOM   1164  CG2 VAL A 158     -36.365  -6.981  13.771  1.00 19.15           C  
ATOM   1165  N   THR A 159     -36.296  -4.753  17.949  1.00 16.36           N  
ATOM   1166  CA  THR A 159     -35.756  -3.928  19.045  1.00 16.11           C  
ATOM   1167  C   THR A 159     -34.607  -4.667  19.617  1.00 15.98           C  
ATOM   1168  O   THR A 159     -34.715  -5.854  20.030  1.00 18.00           O  
ATOM   1169  CB  THR A 159     -36.810  -3.608  20.116  1.00 18.09           C  
ATOM   1170  OG1 THR A 159     -37.974  -3.068  19.480  1.00 18.16           O  
ATOM   1171  CG2 THR A 159     -36.316  -2.594  21.127  1.00 20.00           C  
ATOM   1172  N   PHE A 160     -33.445  -4.010  19.576  1.00 16.68           N  
ATOM   1173  CA  PHE A 160     -32.204  -4.557  20.104  1.00 15.46           C  
ATOM   1174  C   PHE A 160     -32.006  -3.983  21.540  1.00 17.70           C  
ATOM   1175  O   PHE A 160     -32.700  -3.026  21.936  1.00 17.13           O  
ATOM   1176  CB  PHE A 160     -31.012  -4.136  19.248  1.00 15.61           C  
ATOM   1177  CG  PHE A 160     -31.003  -4.735  17.846  1.00 14.47           C  
ATOM   1178  CD1 PHE A 160     -31.679  -4.087  16.803  1.00 14.68           C  
ATOM   1179  CD2 PHE A 160     -30.438  -5.966  17.625  1.00 14.32           C  
ATOM   1180  CE1 PHE A 160     -31.685  -4.624  15.504  1.00 13.14           C  
ATOM   1181  CE2 PHE A 160     -30.429  -6.504  16.353  1.00 14.77           C  
ATOM   1182  CZ  PHE A 160     -31.064  -5.816  15.299  1.00 14.51           C  
ATOM   1183  N   ASP A 161     -31.058  -4.551  22.268  1.00 20.49           N  
ATOM   1184  CA  ASP A 161     -30.673  -3.996  23.596  1.00 24.81           C  
ATOM   1185  C   ASP A 161     -29.745  -2.749  23.521  1.00 25.51           C  
ATOM   1186  O   ASP A 161     -29.488  -2.143  24.536  1.00 21.96           O  
ATOM   1187  CB  ASP A 161     -30.128  -5.077  24.546  1.00 27.50           C  
ATOM   1188  CG  ASP A 161     -28.702  -5.441  24.283  1.00 34.38           C  
ATOM   1189  OD1 ASP A 161     -28.178  -5.181  23.180  1.00 37.05           O  
ATOM   1190  OD2 ASP A 161     -28.065  -6.029  25.177  1.00 38.60           O  
ATOM   1191  N   ASP A 162     -29.298  -2.351  22.332  1.00 20.58           N  
ATOM   1192  CA  ASP A 162     -28.432  -1.192  22.155  1.00 22.17           C  
ATOM   1193  C   ASP A 162     -28.727  -0.518  20.807  1.00 20.91           C  
ATOM   1194  O   ASP A 162     -29.308  -1.171  19.905  1.00 18.96           O  
ATOM   1195  CB  ASP A 162     -26.974  -1.655  22.133  1.00 23.28           C  
ATOM   1196  CG  ASP A 162     -26.014  -0.479  22.165  1.00 26.19           C  
ATOM   1197  OD1 ASP A 162     -26.102   0.393  23.096  1.00 34.09           O  
ATOM   1198  OD2 ASP A 162     -25.213  -0.386  21.247  1.00 25.03           O  
ATOM   1199  N   HIS A 163     -28.368   0.761  20.681  1.00 18.34           N  
ATOM   1200  CA  HIS A 163     -28.531   1.528  19.443  1.00 18.07           C  
ATOM   1201  C   HIS A 163     -27.574   1.127  18.326  1.00 16.32           C  
ATOM   1202  O   HIS A 163     -27.913   1.308  17.153  1.00 16.14           O  
ATOM   1203  CB  HIS A 163     -28.436   3.042  19.684  1.00 19.50           C  
ATOM   1204  CG  HIS A 163     -27.065   3.491  20.030  1.00 22.85           C  
ATOM   1205  ND1 HIS A 163     -26.113   3.804  19.071  1.00 23.62           N  
ATOM   1206  CD2 HIS A 163     -26.460   3.632  21.232  1.00 25.28           C  
ATOM   1207  CE1 HIS A 163     -24.982   4.113  19.681  1.00 25.91           C  
ATOM   1208  NE2 HIS A 163     -25.173   4.028  20.984  1.00 23.10           N  
ATOM   1209  N   ASP A 164     -26.431   0.550  18.654  1.00 14.09           N  
ATOM   1210  CA  ASP A 164     -25.375   0.360  17.673  1.00 13.90           C  
ATOM   1211  C   ASP A 164     -25.754  -0.642  16.538  1.00 15.15           C  
ATOM   1212  O   ASP A 164     -25.454  -0.377  15.366  1.00 14.61           O  
ATOM   1213  CB  ASP A 164     -24.066  -0.045  18.279  1.00 15.36           C  
ATOM   1214  CG  ASP A 164     -22.936  -0.002  17.262  1.00 14.68           C  
ATOM   1215  OD1 ASP A 164     -22.791   1.049  16.562  1.00 16.12           O  
ATOM   1216  OD2 ASP A 164     -22.295  -1.048  17.051  1.00 16.55           O  
ATOM   1217  N   PRO A 165     -26.414  -1.749  16.884  1.00 15.93           N  
ATOM   1218  CA  PRO A 165     -26.917  -2.667  15.832  1.00 14.78           C  
ATOM   1219  C   PRO A 165     -27.811  -1.941  14.811  1.00 14.24           C  
ATOM   1220  O   PRO A 165     -27.625  -2.166  13.615  1.00 12.84           O  
ATOM   1221  CB  PRO A 165     -27.662  -3.741  16.635  1.00 15.77           C  
ATOM   1222  CG  PRO A 165     -26.943  -3.733  17.982  1.00 16.35           C  
ATOM   1223  CD  PRO A 165     -26.638  -2.303  18.243  1.00 16.04           C  
ATOM   1224  N   VAL A 166     -28.671  -1.038  15.262  1.00 13.40           N  
ATOM   1225  CA  VAL A 166     -29.534  -0.280  14.404  1.00 13.55           C  
ATOM   1226  C   VAL A 166     -28.681   0.621  13.517  1.00 15.14           C  
ATOM   1227  O   VAL A 166     -28.867   0.647  12.264  1.00 12.17           O  
ATOM   1228  CB  VAL A 166     -30.580   0.543  15.157  1.00 13.40           C  
ATOM   1229  CG1 VAL A 166     -31.390   1.433  14.255  1.00 13.79           C  
ATOM   1230  CG2 VAL A 166     -31.588  -0.302  15.985  1.00 14.15           C  
ATOM   1231  N   ASP A 167     -27.694   1.283  14.130  1.00 13.75           N  
ATOM   1232  CA  ASP A 167     -26.838   2.182  13.355  1.00 16.33           C  
ATOM   1233  C   ASP A 167     -26.045   1.448  12.308  1.00 14.98           C  
ATOM   1234  O   ASP A 167     -25.909   1.963  11.212  1.00 20.00           O  
ATOM   1235  CB  ASP A 167     -25.884   2.965  14.246  1.00 15.42           C  
ATOM   1236  CG  ASP A 167     -26.586   3.859  15.219  1.00 16.44           C  
ATOM   1237  OD1 ASP A 167     -27.669   4.354  14.895  1.00 20.47           O  
ATOM   1238  OD2 ASP A 167     -26.079   4.101  16.333  1.00 15.71           O  
ATOM   1239  N   LYS A 168     -25.533   0.285  12.620  1.00 13.41           N  
ATOM   1240  CA  LYS A 168     -24.781  -0.505  11.702  1.00 15.06           C  
ATOM   1241  C   LYS A 168     -25.670  -0.995  10.527  1.00 15.50           C  
ATOM   1242  O   LYS A 168     -25.358  -0.867   9.341  1.00 12.99           O  
ATOM   1243  CB  LYS A 168     -24.128  -1.654  12.417  1.00 16.26           C  
ATOM   1244  CG  LYS A 168     -23.311  -2.589  11.562  1.00 18.92           C  
ATOM   1245  CD  LYS A 168     -22.736  -3.783  12.308  1.00 21.78           C  
ATOM   1246  CE  LYS A 168     -21.913  -4.540  11.301  1.00 27.30           C  
ATOM   1247  NZ  LYS A 168     -21.220  -5.731  11.820  1.00 32.86           N  
ATOM   1248  N   ILE A 169     -26.831  -1.501  10.890  1.00 14.89           N  
ATOM   1249  CA  ILE A 169     -27.712  -2.114   9.877  1.00 14.37           C  
ATOM   1250  C   ILE A 169     -28.122  -1.095   8.809  1.00 13.03           C  
ATOM   1251  O   ILE A 169     -28.155  -1.421   7.610  1.00 13.57           O  
ATOM   1252  CB  ILE A 169     -28.935  -2.717  10.572  1.00 14.29           C  
ATOM   1253  CG1 ILE A 169     -28.531  -4.012  11.318  1.00 14.59           C  
ATOM   1254  CG2 ILE A 169     -30.069  -2.964   9.536  1.00 13.46           C  
ATOM   1255  CD1 ILE A 169     -29.536  -4.420  12.400  1.00 15.08           C  
ATOM   1256  N   VAL A 170     -28.495   0.077   9.243  1.00 13.86           N  
ATOM   1257  CA  VAL A 170     -29.024   1.114   8.340  1.00 15.25           C  
ATOM   1258  C   VAL A 170     -27.967   1.803   7.472  1.00 16.34           C  
ATOM   1259  O   VAL A 170     -28.354   2.554   6.594  1.00 16.74           O  
ATOM   1260  CB  VAL A 170     -29.953   2.128   8.977  1.00 16.92           C  
ATOM   1261  CG1 VAL A 170     -31.120   1.439   9.668  1.00 18.58           C  
ATOM   1262  CG2 VAL A 170     -29.188   3.037   9.947  1.00 20.57           C  
ATOM   1263  N   LEU A 171     -26.677   1.522   7.686  1.00 16.61           N  
ATOM   1264  CA  LEU A 171     -25.654   1.906   6.685  1.00 19.36           C  
ATOM   1265  C   LEU A 171     -25.937   1.235   5.355  1.00 18.71           C  
ATOM   1266  O   LEU A 171     -25.545   1.769   4.347  1.00 18.90           O  
ATOM   1267  CB  LEU A 171     -24.245   1.493   7.122  1.00 20.18           C  
ATOM   1268  CG  LEU A 171     -23.756   2.254   8.386  1.00 22.11           C  
ATOM   1269  CD1 LEU A 171     -22.458   1.627   8.803  1.00 22.67           C  
ATOM   1270  CD2 LEU A 171     -23.616   3.730   8.111  1.00 22.87           C  
ATOM   1271  N   GLN A 172     -26.587   0.065   5.370  1.00 18.14           N  
ATOM   1272  CA  GLN A 172     -27.024  -0.643   4.154  1.00 17.36           C  
ATOM   1273  C   GLN A 172     -28.565  -0.586   4.064  1.00 16.83           C  
ATOM   1274  O   GLN A 172     -29.264  -1.191   4.882  1.00 15.19           O  
ATOM   1275  CB  GLN A 172     -26.542  -2.029   4.244  1.00 18.00           C  
ATOM   1276  CG  GLN A 172     -26.821  -2.927   3.050  1.00 21.35           C  
ATOM   1277  CD  GLN A 172     -26.630  -4.365   3.371  1.00 24.52           C  
ATOM   1278  OE1 GLN A 172     -27.403  -5.276   2.970  1.00 26.76           O  
ATOM   1279  NE2 GLN A 172     -25.590  -4.620   4.102  1.00 27.49           N  
ATOM   1280  N   LYS A 173     -29.100   0.166   3.108  1.00 16.45           N  
ATOM   1281  CA  LYS A 173     -30.545   0.386   3.087  1.00 17.08           C  
ATOM   1282  C   LYS A 173     -31.304  -0.903   2.704  1.00 16.65           C  
ATOM   1283  O   LYS A 173     -32.347  -1.212   3.284  1.00 16.07           O  
ATOM   1284  CB  LYS A 173     -30.923   1.486   2.126  1.00 20.35           C  
ATOM   1285  CG  LYS A 173     -32.398   1.850   2.178  1.00 23.16           C  
ATOM   1286  CD  LYS A 173     -32.694   2.927   1.132  1.00 29.97           C  
ATOM   1287  CE  LYS A 173     -34.038   3.558   1.373  1.00 31.47           C  
ATOM   1288  NZ  LYS A 173     -34.336   4.561   0.326  1.00 38.08           N  
ATOM   1289  N   TYR A 174     -30.769  -1.607   1.721  1.00 16.23           N  
ATOM   1290  CA  TYR A 174     -31.395  -2.812   1.137  1.00 15.97           C  
ATOM   1291  C   TYR A 174     -30.811  -4.113   1.548  1.00 14.23           C  
ATOM   1292  O   TYR A 174     -29.582  -4.334   1.437  1.00 15.69           O  
ATOM   1293  CB  TYR A 174     -31.379  -2.645  -0.396  1.00 16.82           C  
ATOM   1294  CG  TYR A 174     -32.149  -1.442  -0.840  1.00 18.10           C  
ATOM   1295  CD1 TYR A 174     -33.469  -1.248  -0.453  1.00 19.70           C  
ATOM   1296  CD2 TYR A 174     -31.566  -0.467  -1.657  1.00 22.74           C  
ATOM   1297  CE1 TYR A 174     -34.174  -0.100  -0.847  1.00 21.11           C  
ATOM   1298  CE2 TYR A 174     -32.272   0.666  -2.084  1.00 22.29           C  
ATOM   1299  CZ  TYR A 174     -33.584   0.825  -1.697  1.00 23.83           C  
ATOM   1300  OH  TYR A 174     -34.320   1.930  -2.060  1.00 25.64           O  
ATOM   1301  N   HIS A 175     -31.679  -5.023   2.005  1.00 13.00           N  
ATOM   1302  CA  HIS A 175     -31.300  -6.326   2.541  1.00 13.60           C  
ATOM   1303  C   HIS A 175     -32.220  -7.361   1.919  1.00 15.54           C  
ATOM   1304  O   HIS A 175     -33.422  -7.147   1.860  1.00 16.79           O  
ATOM   1305  CB  HIS A 175     -31.495  -6.366   4.056  1.00 14.17           C  
ATOM   1306  CG  HIS A 175     -30.569  -5.425   4.828  1.00 12.28           C  
ATOM   1307  ND1 HIS A 175     -29.572  -5.895   5.641  1.00 12.91           N  
ATOM   1308  CD2 HIS A 175     -30.545  -4.085   4.941  1.00 12.14           C  
ATOM   1309  CE1 HIS A 175     -28.893  -4.871   6.152  1.00 12.64           C  
ATOM   1310  NE2 HIS A 175     -29.476  -3.756   5.770  1.00 12.79           N  
ATOM   1311  N   THR A 176     -31.667  -8.445   1.432  1.00 14.82           N  
ATOM   1312  CA  THR A 176     -32.515  -9.611   1.122  1.00 15.57           C  
ATOM   1313  C   THR A 176     -32.911 -10.369   2.345  1.00 14.94           C  
ATOM   1314  O   THR A 176     -32.061 -10.889   3.046  1.00 15.61           O  
ATOM   1315  CB  THR A 176     -31.779 -10.492   0.129  1.00 17.41           C  
ATOM   1316  OG1 THR A 176     -31.476  -9.707  -1.047  1.00 18.00           O  
ATOM   1317  CG2 THR A 176     -32.601 -11.757  -0.229  1.00 18.84           C  
ATOM   1318  N   ILE A 177     -34.214 -10.410   2.643  1.00 14.80           N  
ATOM   1319  CA  ILE A 177     -34.692 -11.065   3.834  1.00 14.12           C  
ATOM   1320  C   ILE A 177     -35.822 -11.961   3.423  1.00 14.34           C  
ATOM   1321  O   ILE A 177     -36.757 -11.493   2.803  1.00 13.37           O  
ATOM   1322  CB  ILE A 177     -35.170 -10.059   4.918  1.00 15.52           C  
ATOM   1323  CG1 ILE A 177     -34.000  -9.129   5.317  1.00 15.33           C  
ATOM   1324  CG2 ILE A 177     -35.709 -10.804   6.151  1.00 15.64           C  
ATOM   1325  CD1 ILE A 177     -34.322  -7.984   6.280  1.00 14.62           C  
ATOM   1326  N   ASN A 178     -35.699 -13.260   3.725  1.00 15.17           N  
ATOM   1327  CA  ASN A 178     -36.725 -14.248   3.432  1.00 16.30           C  
ATOM   1328  C   ASN A 178     -37.120 -14.197   1.967  1.00 16.13           C  
ATOM   1329  O   ASN A 178     -38.305 -14.213   1.605  1.00 16.59           O  
ATOM   1330  CB  ASN A 178     -37.948 -14.068   4.310  1.00 17.13           C  
ATOM   1331  CG  ASN A 178     -38.942 -15.234   4.188  1.00 20.86           C  
ATOM   1332  OD1 ASN A 178     -38.539 -16.381   4.020  1.00 23.41           O  
ATOM   1333  ND2 ASN A 178     -40.232 -14.929   4.219  1.00 20.38           N  
ATOM   1334  N   GLY A 179     -36.116 -14.070   1.127  1.00 16.22           N  
ATOM   1335  CA  GLY A 179     -36.362 -14.007  -0.326  1.00 16.95           C  
ATOM   1336  C   GLY A 179     -36.954 -12.742  -0.888  1.00 16.29           C  
ATOM   1337  O   GLY A 179     -37.275 -12.707  -2.061  1.00 14.73           O  
ATOM   1338  N   HIS A 180     -37.011 -11.685  -0.083  1.00 14.68           N  
ATOM   1339  CA  HIS A 180     -37.625 -10.449  -0.467  1.00 15.46           C  
ATOM   1340  C   HIS A 180     -36.586  -9.373  -0.548  1.00 15.31           C  
ATOM   1341  O   HIS A 180     -35.570  -9.443   0.135  1.00 14.77           O  
ATOM   1342  CB  HIS A 180     -38.671  -9.999   0.538  1.00 16.06           C  
ATOM   1343  CG  HIS A 180     -39.861 -10.889   0.601  1.00 17.24           C  
ATOM   1344  ND1 HIS A 180     -40.677 -11.092  -0.482  1.00 16.95           N  
ATOM   1345  CD2 HIS A 180     -40.368 -11.635   1.605  1.00 16.89           C  
ATOM   1346  CE1 HIS A 180     -41.642 -11.922  -0.158  1.00 18.93           C  
ATOM   1347  NE2 HIS A 180     -41.480 -12.262   1.111  1.00 19.61           N  
ATOM   1348  N   ASN A 181     -36.907  -8.352  -1.340  1.00 14.17           N  
ATOM   1349  CA  ASN A 181     -36.117  -7.146  -1.404  1.00 13.86           C  
ATOM   1350  C   ASN A 181     -36.562  -6.193  -0.308  1.00 14.49           C  
ATOM   1351  O   ASN A 181     -37.340  -5.264  -0.523  1.00 14.47           O  
ATOM   1352  CB  ASN A 181     -36.258  -6.505  -2.760  1.00 14.04           C  
ATOM   1353  CG  ASN A 181     -35.693  -7.379  -3.869  1.00 14.38           C  
ATOM   1354  OD1 ASN A 181     -36.414  -7.742  -4.865  1.00 18.37           O  
ATOM   1355  ND2 ASN A 181     -34.469  -7.734  -3.736  1.00 12.00           N  
ATOM   1356  N   ALA A 182     -36.039  -6.435   0.880  1.00 14.70           N  
ATOM   1357  CA  ALA A 182     -36.434  -5.681   2.049  1.00 13.07           C  
ATOM   1358  C   ALA A 182     -35.660  -4.384   2.189  1.00 14.53           C  
ATOM   1359  O   ALA A 182     -34.624  -4.160   1.544  1.00 12.51           O  
ATOM   1360  CB  ALA A 182     -36.253  -6.542   3.277  1.00 12.76           C  
ATOM   1361  N   GLU A 183     -36.157  -3.559   3.110  1.00 14.09           N  
ATOM   1362  CA  GLU A 183     -35.606  -2.260   3.372  1.00 14.39           C  
ATOM   1363  C   GLU A 183     -35.653  -1.996   4.864  1.00 13.24           C  
ATOM   1364  O   GLU A 183     -36.617  -2.327   5.531  1.00 12.40           O  
ATOM   1365  CB  GLU A 183     -36.448  -1.233   2.619  1.00 17.13           C  
ATOM   1366  CG  GLU A 183     -36.037   0.168   2.837  1.00 19.66           C  
ATOM   1367  CD  GLU A 183     -36.901   1.169   2.061  1.00 23.72           C  
ATOM   1368  OE1 GLU A 183     -37.233   0.848   0.874  1.00 21.74           O  
ATOM   1369  OE2 GLU A 183     -37.203   2.260   2.673  1.00 24.38           O  
ATOM   1370  N   VAL A 184     -34.598  -1.383   5.382  1.00 12.77           N  
ATOM   1371  CA  VAL A 184     -34.485  -1.053   6.821  1.00 11.87           C  
ATOM   1372  C   VAL A 184     -34.488   0.463   7.046  1.00 13.15           C  
ATOM   1373  O   VAL A 184     -33.995   1.214   6.213  1.00 14.36           O  
ATOM   1374  CB  VAL A 184     -33.257  -1.725   7.478  1.00 11.37           C  
ATOM   1375  CG1 VAL A 184     -33.420  -3.222   7.389  1.00 11.29           C  
ATOM   1376  CG2 VAL A 184     -31.926  -1.341   6.746  1.00 11.34           C  
ATOM   1377  N   ARG A 185     -35.074   0.904   8.165  1.00 12.58           N  
ATOM   1378  CA  ARG A 185     -35.087   2.308   8.576  1.00 14.81           C  
ATOM   1379  C   ARG A 185     -34.974   2.363  10.081  1.00 15.36           C  
ATOM   1380  O   ARG A 185     -35.450   1.483  10.759  1.00 15.19           O  
ATOM   1381  CB  ARG A 185     -36.378   3.010   8.172  1.00 16.04           C  
ATOM   1382  CG  ARG A 185     -36.859   2.772   6.729  1.00 17.28           C  
ATOM   1383  CD  ARG A 185     -38.277   3.358   6.545  1.00 20.06           C  
ATOM   1384  NE  ARG A 185     -38.763   3.064   5.195  1.00 18.34           N  
ATOM   1385  CZ  ARG A 185     -40.042   3.115   4.812  1.00 21.80           C  
ATOM   1386  NH1 ARG A 185     -41.001   3.519   5.638  1.00 19.68           N  
ATOM   1387  NH2 ARG A 185     -40.342   2.793   3.564  1.00 24.32           N  
ATOM   1388  N   LYS A 186     -34.416   3.433  10.602  1.00 15.86           N  
ATOM   1389  CA  LYS A 186     -34.395   3.604  12.041  1.00 15.96           C  
ATOM   1390  C   LYS A 186     -35.847   3.870  12.435  1.00 16.35           C  
ATOM   1391  O   LYS A 186     -36.498   4.611  11.791  1.00 16.51           O  
ATOM   1392  CB  LYS A 186     -33.548   4.809  12.455  1.00 16.03           C  
ATOM   1393  CG  LYS A 186     -32.106   4.746  12.050  1.00 16.72           C  
ATOM   1394  CD  LYS A 186     -31.208   5.819  12.687  1.00 17.73           C  
ATOM   1395  CE  LYS A 186     -29.868   5.165  12.988  1.00 18.26           C  
ATOM   1396  NZ  LYS A 186     -28.618   5.474  12.193  1.00 17.58           N  
ATOM   1397  N   ALA A 187     -36.339   3.258  13.491  1.00 17.53           N  
ATOM   1398  CA  ALA A 187     -37.750   3.500  13.916  1.00 17.11           C  
ATOM   1399  C   ALA A 187     -37.835   4.944  14.456  1.00 20.14           C  
ATOM   1400  O   ALA A 187     -37.020   5.321  15.301  1.00 20.22           O  
ATOM   1401  CB  ALA A 187     -38.191   2.509  14.974  1.00 18.76           C  
ATOM   1402  N   LEU A 188     -38.826   5.691  13.990  1.00 20.84           N  
ATOM   1403  CA  LEU A 188     -39.051   7.092  14.376  1.00 26.32           C  
ATOM   1404  C   LEU A 188     -40.446   7.166  14.976  1.00 32.26           C  
ATOM   1405  O   LEU A 188     -41.333   6.422  14.537  1.00 29.91           O  
ATOM   1406  CB  LEU A 188     -39.002   7.955  13.143  1.00 27.08           C  
ATOM   1407  CG  LEU A 188     -37.724   7.913  12.309  1.00 30.09           C  
ATOM   1408  CD1 LEU A 188     -37.760   8.869  11.113  1.00 33.46           C  
ATOM   1409  CD2 LEU A 188     -36.491   8.162  13.171  1.00 30.63           C  
ATOM   1410  N   SER A 189     -40.646   8.021  15.990  1.00 34.86           N  
ATOM   1411  CA  SER A 189     -42.010   8.483  16.379  1.00 39.41           C  
ATOM   1412  C   SER A 189     -42.554   9.308  15.216  1.00 44.07           C  
ATOM   1413  O   SER A 189     -41.767   9.734  14.356  1.00 50.58           O  
ATOM   1414  CB  SER A 189     -41.935   9.381  17.617  1.00 38.70           C  
ATOM   1415  OG  SER A 189     -41.050  10.481  17.369  1.00 42.14           O  
ATOM   1416  N   ARG A 190     -43.855   9.590  15.164  1.00 57.43           N  
ATOM   1417  CA  ARG A 190     -44.368  10.372  14.016  1.00 58.74           C  
ATOM   1418  C   ARG A 190     -43.747  11.770  13.967  1.00 53.19           C  
ATOM   1419  O   ARG A 190     -43.541  12.312  12.882  1.00 50.81           O  
ATOM   1420  CB  ARG A 190     -45.898  10.489  13.953  1.00 63.10           C  
ATOM   1421  CG  ARG A 190     -46.386  10.811  12.514  1.00 69.19           C  
ATOM   1422  CD  ARG A 190     -47.281  12.048  12.373  1.00 71.86           C  
ATOM   1423  NE  ARG A 190     -48.630  11.772  12.870  1.00 77.53           N  
ATOM   1424  CZ  ARG A 190     -49.113  12.093  14.075  1.00 83.92           C  
ATOM   1425  NH1 ARG A 190     -48.392  12.760  14.975  1.00 89.69           N  
ATOM   1426  NH2 ARG A 190     -50.358  11.745  14.391  1.00 83.28           N  
ATOM   1427  N   GLN A 191     -43.413  12.338  15.113  1.00 47.62           N  
ATOM   1428  CA  GLN A 191     -42.807  13.662  15.089  1.00 56.11           C  
ATOM   1429  C   GLN A 191     -41.388  13.690  14.509  1.00 57.97           C  
ATOM   1430  O   GLN A 191     -41.064  14.605  13.743  1.00 55.64           O  
ATOM   1431  CB  GLN A 191     -42.829  14.339  16.455  1.00 63.31           C  
ATOM   1432  CG  GLN A 191     -42.879  15.854  16.329  1.00 69.89           C  
ATOM   1433  CD  GLN A 191     -43.094  16.531  17.664  1.00 80.56           C  
ATOM   1434  OE1 GLN A 191     -44.156  17.104  17.923  1.00 80.01           O  
ATOM   1435  NE2 GLN A 191     -42.086  16.459  18.528  1.00 85.19           N  
ATOM   1436  N   GLU A 192     -40.546  12.708  14.847  1.00 51.92           N  
ATOM   1437  CA  GLU A 192     -39.198  12.662  14.245  1.00 52.27           C  
ATOM   1438  C   GLU A 192     -39.293  12.518  12.719  1.00 54.14           C  
ATOM   1439  O   GLU A 192     -38.399  12.985  11.998  1.00 59.52           O  
ATOM   1440  CB  GLU A 192     -38.341  11.543  14.839  1.00 51.67           C  
ATOM   1441  CG  GLU A 192     -37.771  11.862  16.219  1.00 51.80           C  
ATOM   1442  CD  GLU A 192     -37.578  10.635  17.108  1.00 51.63           C  
ATOM   1443  OE1 GLU A 192     -36.848  10.762  18.114  1.00 51.37           O  
ATOM   1444  OE2 GLU A 192     -38.135   9.542  16.816  1.00 49.16           O  
ATOM   1445  N   MET A 193     -40.382  11.891  12.243  1.00 54.55           N  
ATOM   1446  CA  MET A 193     -40.652  11.744  10.811  1.00 57.60           C  
ATOM   1447  C   MET A 193     -40.911  13.103  10.184  1.00 50.51           C  
ATOM   1448  O   MET A 193     -40.741  13.215   8.991  1.00 50.11           O  
ATOM   1449  CB  MET A 193     -41.839  10.766  10.514  1.00 55.91           C  
ATOM   1450  CG  MET A 193     -41.567   9.293  10.851  1.00 56.13           C  
ATOM   1451  SD  MET A 193     -42.974   8.141  10.842  1.00 52.25           S  
ATOM   1452  CE  MET A 193     -43.047   7.830   9.072  1.00 52.95           C  
TER    1453      MET A 193                                                      
ATOM   1454  O5'   A B   1     -20.000  18.634  21.530  1.00 51.38           O  
ATOM   1455  C5'   A B   1     -20.025  18.571  20.087  1.00 44.48           C  
ATOM   1456  C4'   A B   1     -20.938  17.456  19.640  1.00 42.15           C  
ATOM   1457  O4'   A B   1     -20.810  16.192  20.374  1.00 38.25           O  
ATOM   1458  C3'   A B   1     -22.420  17.682  19.336  1.00 40.30           C  
ATOM   1459  O3'   A B   1     -22.760  17.160  18.053  1.00 34.74           O  
ATOM   1460  C2'   A B   1     -23.096  16.808  20.401  1.00 40.42           C  
ATOM   1461  O2'   A B   1     -24.408  16.433  20.048  1.00 40.50           O  
ATOM   1462  C1'   A B   1     -22.117  15.626  20.505  1.00 38.68           C  
ATOM   1463  N9    A B   1     -22.179  14.902  21.775  1.00 42.52           N  
ATOM   1464  C8    A B   1     -22.448  13.569  21.997  1.00 45.21           C  
ATOM   1465  N7    A B   1     -22.367  13.218  23.260  1.00 39.56           N  
ATOM   1466  C5    A B   1     -22.023  14.397  23.913  1.00 47.07           C  
ATOM   1467  C6    A B   1     -21.779  14.698  25.269  1.00 45.07           C  
ATOM   1468  N6    A B   1     -21.861  13.803  26.251  1.00 41.71           N  
ATOM   1469  N1    A B   1     -21.424  15.966  25.581  1.00 47.75           N  
ATOM   1470  C2    A B   1     -21.322  16.865  24.593  1.00 47.61           C  
ATOM   1471  N3    A B   1     -21.519  16.703  23.284  1.00 47.98           N  
ATOM   1472  C4    A B   1     -21.891  15.438  23.009  1.00 44.29           C  
ATOM   1473  P     A B   2     -23.666  17.963  16.994  1.00 34.63           P  
ATOM   1474  OP1   A B   2     -23.604  19.408  17.319  1.00 35.79           O  
ATOM   1475  OP2   A B   2     -24.988  17.282  16.912  1.00 33.90           O  
ATOM   1476  O5'   A B   2     -22.917  17.636  15.622  1.00 27.33           O  
ATOM   1477  C5'   A B   2     -21.709  18.302  15.225  1.00 22.31           C  
ATOM   1478  C4'   A B   2     -21.533  18.080  13.759  1.00 20.67           C  
ATOM   1479  O4'   A B   2     -21.349  16.653  13.559  1.00 17.80           O  
ATOM   1480  C3'   A B   2     -22.727  18.452  12.872  1.00 20.64           C  
ATOM   1481  O3'   A B   2     -22.303  18.602  11.518  1.00 20.99           O  
ATOM   1482  C2'   A B   2     -23.554  17.161  12.863  1.00 18.83           C  
ATOM   1483  O2'   A B   2     -24.347  16.916  11.719  1.00 19.56           O  
ATOM   1484  C1'   A B   2     -22.437  16.118  12.807  1.00 16.95           C  
ATOM   1485  N9    A B   2     -22.793  14.818  13.379  1.00 15.89           N  
ATOM   1486  C8    A B   2     -23.389  14.519  14.580  1.00 15.65           C  
ATOM   1487  N7    A B   2     -23.595  13.231  14.761  1.00 14.48           N  
ATOM   1488  C5    A B   2     -23.040  12.647  13.632  1.00 14.65           C  
ATOM   1489  C6    A B   2     -22.876  11.307  13.244  1.00 15.12           C  
ATOM   1490  N6    A B   2     -23.280  10.273  13.981  1.00 14.58           N  
ATOM   1491  N1    A B   2     -22.266  11.063  12.062  1.00 13.14           N  
ATOM   1492  C2    A B   2     -21.862  12.103  11.325  1.00 13.49           C  
ATOM   1493  N3    A B   2     -21.938  13.402  11.594  1.00 13.07           N  
ATOM   1494  C4    A B   2     -22.544  13.610  12.773  1.00 13.78           C  
ATOM   1495  P     G B   3     -21.388  19.831  11.032  1.00 22.60           P  
ATOM   1496  OP1   G B   3     -21.502  20.937  11.995  1.00 21.27           O  
ATOM   1497  OP2   G B   3     -21.582  19.935   9.557  1.00 22.59           O  
ATOM   1498  O5'   G B   3     -19.900  19.317  11.207  1.00 19.69           O  
ATOM   1499  C5'   G B   3     -19.511  18.070  10.673  1.00 18.74           C  
ATOM   1500  C4'   G B   3     -18.126  18.204  10.120  1.00 18.39           C  
ATOM   1501  O4'   G B   3     -17.586  16.868   9.979  1.00 14.50           O  
ATOM   1502  C3'   G B   3     -18.039  18.809   8.717  1.00 17.65           C  
ATOM   1503  O3'   G B   3     -16.730  19.301   8.489  1.00 20.18           O  
ATOM   1504  C2'   G B   3     -18.198  17.575   7.837  1.00 17.07           C  
ATOM   1505  O2'   G B   3     -17.757  17.612   6.501  1.00 18.01           O  
ATOM   1506  C1'   G B   3     -17.323  16.592   8.609  1.00 14.16           C  
ATOM   1507  N9    G B   3     -17.536  15.168   8.359  1.00 13.64           N  
ATOM   1508  C8    G B   3     -16.549  14.229   8.162  1.00 14.65           C  
ATOM   1509  N7    G B   3     -17.013  13.022   7.990  1.00 14.57           N  
ATOM   1510  C5    G B   3     -18.393  13.177   8.029  1.00 13.70           C  
ATOM   1511  C6    G B   3     -19.423  12.222   7.876  1.00 13.03           C  
ATOM   1512  O6    G B   3     -19.316  11.005   7.700  1.00 14.51           O  
ATOM   1513  N1    G B   3     -20.680  12.792   8.042  1.00 12.68           N  
ATOM   1514  C2    G B   3     -20.918  14.122   8.286  1.00 13.83           C  
ATOM   1515  N2    G B   3     -22.198  14.475   8.414  1.00 14.33           N  
ATOM   1516  N3    G B   3     -19.963  15.028   8.441  1.00 12.67           N  
ATOM   1517  C4    G B   3     -18.734  14.494   8.270  1.00 13.16           C  
ATOM   1518  P     G B   4     -16.545  20.867   8.073  1.00 27.20           P  
ATOM   1519  OP1   G B   4     -16.877  21.621   9.264  1.00 28.32           O  
ATOM   1520  OP2   G B   4     -17.300  21.049   6.843  1.00 29.32           O  
ATOM   1521  O5'   G B   4     -14.982  20.936   7.784  1.00 25.23           O  
ATOM   1522  C5'   G B   4     -14.078  21.604   8.682  1.00 23.52           C  
ATOM   1523  C4'   G B   4     -12.695  21.145   8.334  1.00 24.97           C  
ATOM   1524  O4'   G B   4     -12.513  19.795   8.851  1.00 20.69           O  
ATOM   1525  C3'   G B   4     -12.436  20.987   6.837  1.00 24.67           C  
ATOM   1526  O3'   G B   4     -12.039  22.205   6.251  1.00 29.36           O  
ATOM   1527  C2'   G B   4     -11.312  19.978   6.801  1.00 25.32           C  
ATOM   1528  O2'   G B   4     -10.174  20.711   7.208  1.00 27.97           O  
ATOM   1529  C1'   G B   4     -11.656  19.079   7.991  1.00 19.03           C  
ATOM   1530  N9    G B   4     -12.307  17.816   7.734  1.00 18.67           N  
ATOM   1531  C8    G B   4     -13.658  17.608   7.596  1.00 19.23           C  
ATOM   1532  N7    G B   4     -13.976  16.344   7.533  1.00 18.32           N  
ATOM   1533  C5    G B   4     -12.770  15.679   7.699  1.00 18.14           C  
ATOM   1534  C6    G B   4     -12.494  14.291   7.767  1.00 17.75           C  
ATOM   1535  O6    G B   4     -13.285  13.349   7.626  1.00 19.23           O  
ATOM   1536  N1    G B   4     -11.128  14.042   7.903  1.00 15.18           N  
ATOM   1537  C2    G B   4     -10.162  15.013   8.041  1.00 15.65           C  
ATOM   1538  N2    G B   4      -8.912  14.589   8.227  1.00 14.10           N  
ATOM   1539  N3    G B   4     -10.416  16.318   8.013  1.00 15.82           N  
ATOM   1540  C4    G B   4     -11.731  16.573   7.832  1.00 17.24           C  
ATOM   1541  P     A B   5     -12.236  22.453   4.622  1.00 33.33           P  
ATOM   1542  OP1   A B   5     -11.869  23.887   4.370  1.00 35.06           O  
ATOM   1543  OP2   A B   5     -13.565  21.949   4.189  1.00 32.49           O  
ATOM   1544  O5'   A B   5     -11.129  21.502   3.988  1.00 35.22           O  
ATOM   1545  C5'   A B   5      -9.721  21.731   4.206  1.00 37.26           C  
ATOM   1546  C4'   A B   5      -8.953  20.589   3.576  1.00 41.50           C  
ATOM   1547  O4'   A B   5      -9.333  19.314   4.200  1.00 38.25           O  
ATOM   1548  C3'   A B   5      -9.215  20.426   2.068  1.00 42.98           C  
ATOM   1549  O3'   A B   5      -8.070  19.983   1.330  1.00 46.59           O  
ATOM   1550  C2'   A B   5     -10.216  19.279   2.024  1.00 41.62           C  
ATOM   1551  O2'   A B   5     -10.200  18.688   0.739  1.00 37.36           O  
ATOM   1552  C1'   A B   5      -9.701  18.403   3.178  1.00 39.25           C  
ATOM   1553  N9    A B   5     -10.667  17.400   3.663  1.00 36.69           N  
ATOM   1554  C8    A B   5     -12.039  17.478   3.633  1.00 38.71           C  
ATOM   1555  N7    A B   5     -12.641  16.370   3.995  1.00 32.87           N  
ATOM   1556  C5    A B   5     -11.599  15.495   4.259  1.00 30.50           C  
ATOM   1557  C6    A B   5     -11.577  14.158   4.684  1.00 34.60           C  
ATOM   1558  N6    A B   5     -12.685  13.444   4.935  1.00 38.42           N  
ATOM   1559  N1    A B   5     -10.367  13.572   4.860  1.00 31.48           N  
ATOM   1560  C2    A B   5      -9.264  14.296   4.619  1.00 33.84           C  
ATOM   1561  N3    A B   5      -9.159  15.564   4.215  1.00 30.30           N  
ATOM   1562  C4    A B   5     -10.376  16.113   4.054  1.00 33.51           C  
ATOM   1563  P     C B   6      -6.856  20.990   0.987  1.00 49.81           P  
ATOM   1564  OP1   C B   6      -5.953  21.070   2.155  1.00 49.32           O  
ATOM   1565  OP2   C B   6      -7.453  22.222   0.436  1.00 51.10           O  
ATOM   1566  O5'   C B   6      -6.085  20.187  -0.144  1.00 50.94           O  
ATOM   1567  C5'   C B   6      -6.662  20.074  -1.452  1.00 48.43           C  
ATOM   1568  C4'   C B   6      -5.886  19.058  -2.230  1.00 48.69           C  
ATOM   1569  O4'   C B   6      -4.467  19.416  -2.255  1.00 51.11           O  
ATOM   1570  C3'   C B   6      -5.876  17.653  -1.649  1.00 47.53           C  
ATOM   1571  O3'   C B   6      -6.927  16.803  -2.079  1.00 34.58           O  
ATOM   1572  C2'   C B   6      -4.673  17.074  -2.385  1.00 49.67           C  
ATOM   1573  O2'   C B   6      -5.054  16.770  -3.732  1.00 43.06           O  
ATOM   1574  C1'   C B   6      -3.677  18.233  -2.262  1.00 48.71           C  
ATOM   1575  P     U B   7      -8.322  16.586  -1.310  1.00 25.89           P  
ATOM   1576  OP1   U B   7      -8.211  17.129   0.038  1.00 30.07           O  
ATOM   1577  OP2   U B   7      -8.694  15.161  -1.611  1.00 21.58           O  
ATOM   1578  O5'   U B   7      -9.299  17.521  -2.154  1.00 20.60           O  
ATOM   1579  C5'   U B   7      -9.357  17.339  -3.581  1.00 18.10           C  
ATOM   1580  C4'   U B   7     -10.407  18.234  -4.184  1.00 16.89           C  
ATOM   1581  O4'   U B   7     -11.703  17.798  -3.709  1.00 17.55           O  
ATOM   1582  C3'   U B   7     -10.278  19.702  -3.789  1.00 17.47           C  
ATOM   1583  O3'   U B   7     -10.598  20.534  -4.886  1.00 20.58           O  
ATOM   1584  C2'   U B   7     -11.267  19.831  -2.643  1.00 16.66           C  
ATOM   1585  O2'   U B   7     -11.704  21.155  -2.348  1.00 18.93           O  
ATOM   1586  C1'   U B   7     -12.368  18.898  -3.141  1.00 16.58           C  
ATOM   1587  N1    U B   7     -13.228  18.461  -2.046  1.00 17.90           N  
ATOM   1588  C2    U B   7     -14.562  18.854  -2.065  1.00 18.12           C  
ATOM   1589  O2    U B   7     -15.077  19.444  -3.007  1.00 18.88           O  
ATOM   1590  N3    U B   7     -15.272  18.521  -0.942  1.00 18.33           N  
ATOM   1591  C4    U B   7     -14.820  17.829   0.160  1.00 19.31           C  
ATOM   1592  O4    U B   7     -15.606  17.565   1.067  1.00 17.70           O  
ATOM   1593  C5    U B   7     -13.449  17.418   0.086  1.00 18.47           C  
ATOM   1594  C6    U B   7     -12.707  17.774  -0.967  1.00 19.69           C  
ATOM   1595  P     A B   8     -10.036  22.010  -4.989  1.00 24.58           P  
ATOM   1596  OP1   A B   8      -8.864  22.128  -4.076  1.00 23.56           O  
ATOM   1597  OP2   A B   8     -11.123  22.961  -4.831  1.00 22.74           O  
ATOM   1598  O5'   A B   8      -9.631  22.063  -6.527  1.00 25.16           O  
ATOM   1599  C5'   A B   8      -8.751  21.100  -7.128  1.00 24.19           C  
ATOM   1600  C4'   A B   8      -8.455  21.526  -8.538  1.00 26.06           C  
ATOM   1601  O4'   A B   8      -9.717  21.565  -9.248  1.00 24.07           O  
ATOM   1602  C3'   A B   8      -7.841  22.922  -8.706  1.00 25.65           C  
ATOM   1603  O3'   A B   8      -7.144  23.155  -9.943  1.00 26.79           O  
ATOM   1604  C2'   A B   8      -9.085  23.790  -8.795  1.00 26.51           C  
ATOM   1605  O2'   A B   8      -8.943  24.973  -9.538  1.00 26.28           O  
ATOM   1606  C1'   A B   8     -10.010  22.893  -9.614  1.00 24.50           C  
ATOM   1607  N9    A B   8     -11.437  23.154  -9.405  1.00 23.94           N  
ATOM   1608  C8    A B   8     -12.098  23.395  -8.227  1.00 23.19           C  
ATOM   1609  N7    A B   8     -13.371  23.676  -8.383  1.00 20.34           N  
ATOM   1610  C5    A B   8     -13.548  23.666  -9.759  1.00 20.08           C  
ATOM   1611  C6    A B   8     -14.683  23.860 -10.563  1.00 20.07           C  
ATOM   1612  N6    A B   8     -15.898  24.127 -10.071  1.00 17.69           N  
ATOM   1613  N1    A B   8     -14.541  23.713 -11.901  1.00 21.78           N  
ATOM   1614  C2    A B   8     -13.328  23.409 -12.388  1.00 21.14           C  
ATOM   1615  N3    A B   8     -12.182  23.204 -11.728  1.00 21.04           N  
ATOM   1616  C4    A B   8     -12.366  23.348 -10.403  1.00 22.27           C  
ATOM   1617  P     G B   9      -5.771  22.401 -10.324  1.00 33.10           P  
ATOM   1618  OP1   G B   9      -5.014  22.170  -9.082  1.00 29.40           O  
ATOM   1619  OP2   G B   9      -5.166  23.101 -11.493  1.00 36.26           O  
ATOM   1620  O5'   G B   9      -6.234  21.044 -11.000  1.00 34.77           O  
ATOM   1621  C5'   G B   9      -7.257  21.012 -11.996  1.00 36.23           C  
ATOM   1622  C4'   G B   9      -6.903  19.934 -12.972  1.00 38.61           C  
ATOM   1623  O4'   G B   9      -8.108  19.499 -13.643  1.00 37.69           O  
ATOM   1624  C3'   G B   9      -5.907  20.321 -14.069  1.00 41.23           C  
ATOM   1625  O3'   G B   9      -5.159  19.176 -14.439  1.00 47.56           O  
ATOM   1626  C2'   G B   9      -6.801  20.608 -15.272  1.00 41.78           C  
ATOM   1627  O2'   G B   9      -6.197  20.440 -16.546  1.00 41.14           O  
ATOM   1628  C1'   G B   9      -7.932  19.598 -15.049  1.00 38.32           C  
ATOM   1629  N9    G B   9      -9.201  20.016 -15.635  1.00 31.51           N  
ATOM   1630  C8    G B   9     -10.004  19.291 -16.481  1.00 30.10           C  
ATOM   1631  N7    G B   9     -11.080  19.933 -16.839  1.00 29.30           N  
ATOM   1632  C5    G B   9     -10.997  21.143 -16.165  1.00 30.84           C  
ATOM   1633  C6    G B   9     -11.877  22.251 -16.162  1.00 31.17           C  
ATOM   1634  O6    G B   9     -12.948  22.384 -16.764  1.00 35.14           O  
ATOM   1635  N1    G B   9     -11.404  23.276 -15.355  1.00 32.59           N  
ATOM   1636  C2    G B   9     -10.237  23.235 -14.630  1.00 33.07           C  
ATOM   1637  N2    G B   9      -9.961  24.312 -13.892  1.00 39.67           N  
ATOM   1638  N3    G B   9      -9.410  22.208 -14.621  1.00 32.05           N  
ATOM   1639  C4    G B   9      -9.842  21.209 -15.419  1.00 30.92           C  
ATOM   1640  P     C B  10      -3.589  19.132 -14.205  1.00 54.40           P  
ATOM   1641  OP1   C B  10      -3.158  17.761 -14.541  1.00 47.37           O  
ATOM   1642  OP2   C B  10      -3.302  19.723 -12.869  1.00 44.55           O  
ATOM   1643  O5'   C B  10      -3.035  20.214 -15.251  1.00 54.84           O  
ATOM   1644  C5'   C B  10      -2.733  19.875 -16.620  1.00 53.65           C  
ATOM   1645  C4'   C B  10      -1.755  20.877 -17.173  1.00 57.37           C  
ATOM   1646  O4'   C B  10      -2.452  22.136 -17.343  1.00 56.73           O  
TER    1647        C B  10                                                      
HETATM 1648  O   HOH A 201     -42.367  -3.491  18.458  1.00 36.03           O  
HETATM 1649  O   HOH A 202     -17.386   8.270   4.553  1.00 44.36           O  
HETATM 1650  O   HOH A 203     -27.927  10.799  -3.990  1.00 33.57           O  
HETATM 1651  O   HOH A 204     -54.178  -8.399  13.267  1.00 27.11           O  
HETATM 1652  O   HOH A 205     -25.612   8.859  -2.808  1.00 29.98           O  
HETATM 1653  O   HOH A 206      -6.407  12.064   6.772  1.00 27.59           O  
HETATM 1654  O   HOH A 207     -15.310  10.022   5.073  1.00 49.62           O  
HETATM 1655  O   HOH A 208     -54.044  -3.354   5.835  1.00 41.21           O  
HETATM 1656  O   HOH A 209     -25.417  -5.308   7.032  1.00 65.99           O  
HETATM 1657  O   HOH A 210     -14.847  31.524  14.606  1.00 27.08           O  
HETATM 1658  O   HOH A 211     -17.527  17.730  24.241  1.00 34.44           O  
HETATM 1659  O   HOH A 212     -19.463  -4.602  17.694  1.00 29.66           O  
HETATM 1660  O   HOH A 213      -8.560   6.975  27.914  1.00 27.82           O  
HETATM 1661  O   HOH A 214     -28.100 -13.669  12.027  1.00 28.39           O  
HETATM 1662  O   HOH A 215     -22.192   4.627  21.464  1.00 26.36           O  
HETATM 1663  O   HOH A 216     -29.751   4.251  16.432  1.00 24.73           O  
HETATM 1664  O   HOH A 217     -27.932 -11.839   8.604  1.00 27.22           O  
HETATM 1665  O   HOH A 218     -39.758  -4.560  18.303  1.00 21.48           O  
HETATM 1666  O   HOH A 219     -14.143  -5.948   7.936  1.00 24.65           O  
HETATM 1667  O   HOH A 220     -11.180  17.904  21.469  1.00 16.71           O  
HETATM 1668  O   HOH A 221     -13.797  -5.717  21.069  1.00 24.95           O  
HETATM 1669  O   HOH A 222      -4.086   7.375   6.005  1.00 31.00           O  
HETATM 1670  O   HOH A 223     -28.870   7.682   9.818  1.00 31.45           O  
HETATM 1671  O   HOH A 224      -9.297   7.302   5.655  1.00 18.44           O  
HETATM 1672  O   HOH A 225      -2.542   2.724  21.012  1.00 30.73           O  
HETATM 1673  O   HOH A 226     -17.450  -1.614   1.476  1.00 30.55           O  
HETATM 1674  O   HOH A 227     -14.978  -2.931  -1.080  1.00 45.60           O  
HETATM 1675  O   HOH A 228     -40.689  -6.411  -1.117  1.00 29.53           O  
HETATM 1676  O   HOH A 229     -33.921  -4.819  -0.951  1.00 13.10           O  
HETATM 1677  O   HOH A 230     -10.779   1.969  27.170  1.00 43.27           O  
HETATM 1678  O   HOH A 231     -32.819   3.585   5.763  1.00 26.42           O  
HETATM 1679  O   HOH A 232     -25.703   8.545   1.841  1.00 25.47           O  
HETATM 1680  O   HOH A 233     -25.234   6.311  13.359  1.00 22.80           O  
HETATM 1681  O   HOH A 234     -29.279   8.879  -0.221  1.00 37.58           O  
HETATM 1682  O   HOH A 235     -23.382   3.674  16.457  1.00 13.41           O  
HETATM 1683  O   HOH A 236     -44.504  -9.940   7.192  1.00 21.52           O  
HETATM 1684  O   HOH A 237     -24.754   2.486  24.126  1.00 41.35           O  
HETATM 1685  O   HOH A 238      -9.135  -5.134  16.966  1.00 27.13           O  
HETATM 1686  O   HOH A 239     -40.272 -15.026  -0.050  1.00 17.73           O  
HETATM 1687  O   HOH A 240     -11.841  10.037  10.335  1.00 12.75           O  
HETATM 1688  O   HOH A 241     -30.476   3.169   5.042  1.00 24.69           O  
HETATM 1689  O   HOH A 242     -26.335   4.766  10.936  1.00 25.85           O  
HETATM 1690  O   HOH A 243     -19.562   3.545  10.056  1.00 14.06           O  
HETATM 1691  O   HOH A 244     -34.273  -2.869  24.143  1.00 24.35           O  
HETATM 1692  O   HOH A 245     -51.962  -2.736  11.754  1.00 35.31           O  
HETATM 1693  O   HOH A 246     -12.178  13.349  25.365  1.00 15.55           O  
HETATM 1694  O   HOH A 247     -31.760 -13.519   3.717  1.00 27.65           O  
HETATM 1695  O   HOH A 248     -11.024  -4.110  23.636  1.00 37.46           O  
HETATM 1696  O   HOH A 249     -12.524  10.910   6.502  1.00 31.94           O  
HETATM 1697  O   HOH A 250     -44.500 -14.320  13.124  1.00 31.17           O  
HETATM 1698  O   HOH A 251     -11.460   8.942   6.672  1.00 39.52           O  
HETATM 1699  O   HOH A 252     -18.599   5.380  25.236  1.00 22.48           O  
HETATM 1700  O   HOH A 253      -5.353   8.566  24.479  1.00 24.85           O  
HETATM 1701  O   HOH A 254      -7.550  20.067  21.971  1.00 37.48           O  
HETATM 1702  O   HOH A 255     -24.444   7.072   6.484  1.00 26.15           O  
HETATM 1703  O   HOH A 256      -9.885  23.224  22.592  1.00 27.16           O  
HETATM 1704  O   HOH A 257     -14.841  -0.230  28.200  1.00 31.00           O  
HETATM 1705  O   HOH A 258     -32.559  -7.255  -1.776  1.00 12.98           O  
HETATM 1706  O   HOH A 259     -22.425  10.779  19.514  1.00 23.56           O  
HETATM 1707  O   HOH A 260     -32.639  10.003  19.374  1.00 33.39           O  
HETATM 1708  O   HOH A 261     -27.458   1.646   1.416  1.00 39.27           O  
HETATM 1709  O   HOH A 262     -33.460 -14.607   1.780  1.00 21.04           O  
HETATM 1710  O   HOH A 263     -60.240  -4.740   6.425  1.00 33.60           O  
HETATM 1711  O   HOH A 264     -33.784 -14.125   5.561  1.00 24.86           O  
HETATM 1712  O   HOH A 265      -9.873   8.953  30.388  1.00 31.09           O  
HETATM 1713  O   HOH A 266     -27.944 -12.115  19.042  1.00 27.91           O  
HETATM 1714  O   HOH A 267     -39.540  -1.540  21.263  1.00 33.42           O  
HETATM 1715  O   HOH A 268     -38.998  -6.599  -4.876  1.00 17.78           O  
HETATM 1716  O   HOH A 269     -24.339  -3.039   7.837  1.00 38.22           O  
HETATM 1717  O   HOH A 270     -33.152   5.134   8.722  1.00 21.14           O  
HETATM 1718  O   HOH A 271     -19.311   0.810  10.563  1.00 18.32           O  
HETATM 1719  O   HOH A 272      -4.852   6.151  24.637  1.00 35.23           O  
HETATM 1720  O   HOH A 273     -15.220  11.063   2.413  1.00 16.56           O  
HETATM 1721  O   HOH A 274     -35.649   6.333   9.679  1.00 28.81           O  
HETATM 1722  O   HOH A 275     -46.304 -12.468   0.663  1.00 20.63           O  
HETATM 1723  O   HOH A 276     -12.664  -0.533  26.354  1.00 33.57           O  
HETATM 1724  O   HOH A 277     -30.473 -11.995  20.052  1.00 25.40           O  
HETATM 1725  O   HOH A 278     -39.333  -4.533  -2.472  1.00 32.31           O  
HETATM 1726  O   HOH A 279     -19.605  19.911   5.398  1.00 26.45           O  
HETATM 1727  O   HOH A 280     -34.145 -15.073   7.725  1.00 26.97           O  
HETATM 1728  O   HOH A 281     -31.703  13.675  13.165  1.00 35.32           O  
HETATM 1729  O   HOH A 282      -7.193   9.172  27.846  1.00 28.70           O  
HETATM 1730  O   HOH A 283     -45.248 -10.153  16.163  1.00 29.17           O  
HETATM 1731  O   HOH A 284     -35.784 -18.201  15.396  1.00 46.25           O  
HETATM 1732  O   HOH A 285     -36.162 -17.875   4.821  1.00 54.87           O  
HETATM 1733  O   HOH A 286      -2.980  -0.046  15.789  1.00 34.61           O  
HETATM 1734  O   HOH A 287     -27.587  -3.033  -0.262  1.00 27.46           O  
HETATM 1735  O   HOH A 288     -40.467 -10.280  20.900  1.00 34.23           O  
HETATM 1736  O   HOH A 289     -42.192 -16.992  14.068  1.00 30.81           O  
HETATM 1737  O   HOH A 290     -34.963   3.305  21.471  1.00 36.40           O  
HETATM 1738  O   HOH A 291     -26.859 -10.102   7.097  1.00 33.54           O  
HETATM 1739  O   HOH A 292     -50.842 -12.643   6.098  1.00 30.63           O  
HETATM 1740  O   HOH A 293     -45.999  -7.950   8.203  1.00 21.07           O  
HETATM 1741  O   HOH A 294     -30.244  12.972  -0.825  1.00 40.97           O  
HETATM 1742  O   HOH A 295     -17.084  -2.960   5.240  1.00 37.02           O  
HETATM 1743  O   HOH A 296      -1.060   9.563  17.815  1.00 35.11           O  
HETATM 1744  O   HOH A 297      -4.938  15.136  24.773  1.00 33.55           O  
HETATM 1745  O   HOH A 298     -20.115  -2.432  24.041  1.00 34.70           O  
HETATM 1746  O   HOH A 299     -11.560  21.351  12.010  1.00 24.02           O  
HETATM 1747  O   HOH A 300     -49.699  -6.703   3.042  1.00 39.22           O  
HETATM 1748  O   HOH A 301     -40.887 -18.265   3.347  1.00 39.28           O  
HETATM 1749  O   HOH A 302     -49.949  -5.713  14.633  1.00 33.26           O  
HETATM 1750  O   HOH A 303     -54.885  -2.335  10.897  1.00 36.33           O  
HETATM 1751  O   HOH A 304     -21.223  -3.018  19.278  1.00 38.78           O  
HETATM 1752  O   HOH A 305     -28.171  -0.669   0.075  1.00 26.34           O  
HETATM 1753  O   HOH A 306     -36.644  -4.771  24.383  1.00 45.03           O  
HETATM 1754  O   HOH A 307     -11.873  29.639  21.892  1.00 47.04           O  
HETATM 1755  O   HOH A 308     -41.985  -1.884  20.641  1.00 40.42           O  
HETATM 1756  O   HOH A 309     -23.033  -7.630   7.360  1.00 42.29           O  
HETATM 1757  O   HOH A 310     -20.772  -1.378   9.171  1.00 33.25           O  
HETATM 1758  O   HOH A 311     -11.360  25.292  24.431  1.00 42.60           O  
HETATM 1759  O   HOH A 312     -26.828   8.529  14.428  1.00 29.24           O  
HETATM 1760  O   HOH A 313     -22.585  -5.088   8.053  1.00 51.56           O  
HETATM 1761  O   HOH A 314      -9.395  -5.629  19.472  1.00 33.45           O  
HETATM 1762  O   HOH A 315     -32.785 -14.226  -2.840  1.00 28.73           O  
HETATM 1763  O   HOH B 101     -10.447  16.252   0.994  1.00 63.16           O  
HETATM 1764  O   HOH B 102     -14.966  17.162   3.536  1.00 36.02           O  
HETATM 1765  O   HOH B 103     -17.568  15.751   4.790  1.00 43.20           O  
HETATM 1766  O   HOH B 104     -26.499  15.931  15.335  1.00 40.68           O  
HETATM 1767  O   HOH B 105     -18.950  19.872  23.525  1.00 41.91           O  
HETATM 1768  O   HOH B 106     -10.908  13.931  -2.084  1.00 19.33           O  
HETATM 1769  O   HOH B 107     -21.540  18.776   7.213  1.00 34.12           O  
HETATM 1770  O   HOH B 108      -9.730  23.284   7.645  1.00 26.54           O  
HETATM 1771  O   HOH B 109     -11.630  24.316  -2.607  1.00 33.39           O  
HETATM 1772  O   HOH B 110     -13.751  20.219   2.081  1.00 42.05           O  
HETATM 1773  O   HOH B 111     -25.755  10.900  15.068  1.00 33.59           O  
HETATM 1774  O   HOH B 112     -15.586  18.821   5.142  1.00 31.99           O  
HETATM 1775  O   HOH B 113      -7.298  12.582  -1.949  1.00 29.54           O  
HETATM 1776  O   HOH B 114     -23.327  17.159   8.920  1.00 23.00           O  
HETATM 1777  O   HOH B 115     -10.324  25.704  -5.984  1.00 35.42           O  
HETATM 1778  O   HOH B 116     -15.841  15.414   5.192  1.00 31.40           O  
HETATM 1779  O   HOH B 117     -11.077  14.285   0.915  1.00 37.87           O  
MASTER      298    0    0    8   11    0    0    6 1769    2    0   15          
END

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Related entries of code: 5ho4

Entries with 90% protein sequence similarity cutoff in PDBbind
PDB Code	Check Database	Protein Sequence Similarity
5en1	RCSB PDB PDBbind	184aa, >5EN1_1\|Chain... *
5wwe	RCSB PDB PDBbind	184aa, >5WWE_1\|Chain... at 100%
5wwf	RCSB PDB PDBbind	184aa, >5WWF_1\|Chains... at 100%
5wwg	RCSB PDB PDBbind	184aa, >5WWG_1\|Chain... at 100%
Complexes with the same small molecule ligand
PDB Code	Check Database	Ligand Name
3d2w	RCSB PDB PDBbind	10-mer
3glf	RCSB PDB PDBbind	10-mer
3i5x	RCSB PDB PDBbind	10-mer
3k49	RCSB PDB PDBbind	10-mer
3k4e	RCSB PDB PDBbind	10-mer
3kde	RCSB PDB PDBbind	10-mer
3kjo	RCSB PDB PDBbind	10-mer
5zva	RCSB PDB PDBbind	10-mer
6kbs	RCSB PDB PDBbind	10-mer
6iir	RCSB PDB PDBbind	10-mer
5zc9	RCSB PDB PDBbind	10-mer

Entry Information

PDB ID	5ho4
Complex Type	Protein-Nucleic Acid
PDBbind Subset	general set
Protein Name	RRMs (aa 12-195) of hnRNP A2/B1
Ligand Name	10-mer
EC.Number	E.C.-.-.-.-
Resolution	1.85(Å)
Affinity (Kd/Ki/IC50)	Kd=114.7nM
Release Year	2017
Protein/NA Sequence	Check fasta file
Primary Reference	(2018) Nat Commun Vol. 9: pp. 420

Links to External Databases

RCSB PDB	The mother database
PDBsum	Enhanced annotations on PDB entries
Pubchem	Comprehensive collection of chemical and biological data
UniProtKB AC	UniProt accession number (AC): P22626
Entrez Gene ID	NCBI Entrez Gene ID: 3181
ASD	Information of known allosteric effects of PDB entries

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